locus-tag	class	description
KM415_RS00010	COG0592	DNA-directed DNA polymerase activity
KM415_RS00015	COG2501	S4 domain
KM415_RS00025	COG0187	DNA topoisomerase II activity
KM415_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM415_RS00065	COG0516	GMP reductase activity
KM415_RS00065	COG0517	IMP dehydrogenase activity
KM415_RS00070	COG1686	Belongs to the peptidase S11 family
KM415_RS00100	COG1428	Deoxynucleoside kinase
KM415_RS00105	COG1428	Deoxynucleoside kinase
KM415_RS00110	COG1335	isochorismatase
KM415_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM415_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM415_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM415_RS00190	COG0470	DNA polymerase III
KM415_RS00195	COG1774	PSP1 C-terminal conserved region
KM415_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM415_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM415_RS00220	COG2002	toxin-antitoxin pair type II binding
KM415_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM415_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM415_RS00230	COG0084	hydrolase, TatD family'
KM415_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM415_RS00250	COG4466	Protein conserved in bacteria
KM415_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM415_RS00270	COG0251	oxidation-reduction process
KM415_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM415_RS00305	COG2002	toxin-antitoxin pair type II binding
KM415_RS00310	COG2244	polysaccharide biosynthetic process
KM415_RS00315	COG3956	TIGRFAM MazG family protein
KM415_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM415_RS00340	COG1098	S1 RNA binding domain
KM415_RS00355	COG2208	phosphoserine phosphatase activity
KM415_RS00360	COG0037	tRNA processing
KM415_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM415_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM415_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM415_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM415_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM415_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM415_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM415_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM415_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM415_RS00420	COG1396	sequence-specific DNA binding
KM415_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM415_RS00455	COG3880	PFAM UvrB UvrC protein
KM415_RS00465	COG0542	response to heat
KM415_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM415_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM415_RS00500	COG1045	serine acetyltransferase
KM415_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM415_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM415_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM415_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM415_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM415_RS00565	COG2813	Specifically methylates the guanine in position
KM415_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM415_RS00580	COG1358	cellular component organization or biogenesis
KM415_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM415_RS00710	COG0201	protein transport
KM415_RS00720	COG0024	Methionine aminopeptidase
KM415_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM415_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM415_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM415_RS00795	COG0489	protein tyrosine kinase activity
KM415_RS00805	COG2194	sulfuric ester hydrolase activity
KM415_RS00810	COG0726	polysaccharide deacetylase
KM415_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM415_RS00895	COG4856	YbbR-like protein
KM415_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM415_RS00915	COG0596	Alpha beta hydrolase
KM415_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM415_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM415_RS00940	COG1506	peptidase
KM415_RS00940	COG4946	Tricorn protease homolog
KM415_RS00975	COG2011	ABC-type metal ion transport system permease component
KM415_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM415_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM415_RS00990	COG0604	alcohol dehydrogenase
KM415_RS01000	COG0277	FAD linked oxidase domain protein
KM415_RS01005	COG2271	Major facilitator Superfamily
KM415_RS01015	COG2814	Major facilitator Superfamily
KM415_RS01030	COG0601	transmembrane transport
KM415_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM415_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM415_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM415_RS01050	COG4166	transmembrane transport
KM415_RS01060	COG2207	Transcriptional regulator
KM415_RS01075	COG4166	transmembrane transport
KM415_RS01080	COG4166	transmembrane transport
KM415_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM415_RS01105	COG4149	molybdate abc transporter
KM415_RS01115	COG1910	domain protein
KM415_RS01125	COG0583	DNA-binding transcription factor activity
KM415_RS01130	COG0697	spore germination
KM415_RS01145	COG0204	Acyl-transferase
KM415_RS01155	COG1609	Transcriptional regulator
KM415_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS01175	COG0084	hydrolase, TatD family'
KM415_RS01180	COG5298	Protein conserved in bacteria
KM415_RS01205	COG0488	(ABC) transporter
KM415_RS01220	COG0747	negative chemotaxis
KM415_RS01225	COG0601	transmembrane transport
KM415_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM415_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM415_RS01240	COG4608	Belongs to the ABC transporter superfamily
KM415_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM415_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM415_RS01290	COG2814	Major facilitator Superfamily
KM415_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM415_RS01310	COG4294	response to UV
KM415_RS01315	COG0457	Tetratricopeptide repeat
KM415_RS01315	COG0705	Rhomboid family
KM415_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM415_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM415_RS01335	COG0864	Transcriptional regulator
KM415_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM415_RS01345	COG2183	response to ionizing radiation
KM415_RS01440	COG0802	atpase or kinase
KM415_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
KM415_RS01450	COG0456	acetyltransferase
KM415_RS01460	COG0488	(ABC) transporter
KM415_RS01475	COG1266	CAAX protease self-immunity
KM415_RS01495	COG2252	PERMEase
KM415_RS01505	COG5002	protein histidine kinase activity
KM415_RS01535	COG2226	methyltransferase
KM415_RS01580	COG1968	undecaprenyl-diphosphatase activity
KM415_RS01595	COG2205	protein histidine kinase activity
KM415_RS01600	COG0745	RESPONSE REGULATOR receiver
KM415_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM415_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM415_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM415_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM415_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM415_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM415_RS01680	COG0151	Belongs to the GarS family
KM415_RS01705	COG0210	DNA helicase
KM415_RS01715	COG4851	CamS sex pheromone cAM373 precursor
KM415_RS01735	COG1335	isochorismatase
KM415_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM415_RS01745	COG2011	ABC-type metal ion transport system permease component
KM415_RS01750	COG1464	Belongs to the NlpA lipoprotein family
KM415_RS01775	COG1846	Transcriptional regulator
KM415_RS01800	COG1597	lipid kinase activity
KM415_RS01805	COG0546	phosphoglycolate phosphatase activity
KM415_RS01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM415_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS01825	COG2076	Multidrug Resistance protein
KM415_RS01830	COG2309	aminopeptidase activity
KM415_RS01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM415_RS01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM415_RS01865	COG4807	Protein conserved in bacteria
KM415_RS01890	COG1757	Na H antiporter
KM415_RS01895	COG1473	amidohydrolase
KM415_RS01910	COG0450	alkyl hydroperoxide reductase
KM415_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS01940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM415_RS01955	COG0166	Belongs to the GPI family
KM415_RS01990	COG5002	protein histidine kinase activity
KM415_RS02010	COG3541	Predicted nucleotidyltransferase
KM415_RS02015	COG2814	Major facilitator Superfamily
KM415_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
KM415_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM415_RS02030	COG0765	amino acid transport
KM415_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM415_RS02045	COG0840	transmembrane signaling receptor activity
KM415_RS02050	COG0840	transmembrane signaling receptor activity
KM415_RS02055	COG0366	Alpha amylase catalytic
KM415_RS02060	COG1263	PTS System
KM415_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM415_RS02060	COG2190	(PTS) system
KM415_RS02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM415_RS02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM415_RS02115	COG1116	anion transmembrane transporter activity
KM415_RS02120	COG0488	(ABC) transporter
KM415_RS02165	COG2270	Major facilitator Superfamily
KM415_RS02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM415_RS02195	COG2310	stress, protein
KM415_RS02200	COG2310	stress, protein
KM415_RS02205	COG2310	stress, protein
KM415_RS02210	COG0861	Integral membrane protein TerC family
KM415_RS02220	COG3853	Toxic anion resistance protein (TelA)
KM415_RS02235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM415_RS02245	COG1295	ribonuclease BN
KM415_RS02250	COG2217	Heavy metal translocating P-type atpase
KM415_RS02255	COG0697	spore germination
KM415_RS02275	COG0586	Pfam SNARE associated Golgi protein
KM415_RS02290	COG3871	stress protein (general stress protein 26)
KM415_RS02295	COG0387	Pfam Sodium calcium exchanger
KM415_RS02305	COG0535	radical SAM domain protein
KM415_RS02330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM415_RS02335	COG0582	viral genome integration into host DNA
KM415_RS02345	COG1396	sequence-specific DNA binding
KM415_RS02360	COG1396	sequence-specific DNA binding
KM415_RS02395	COG1484	DNA-dependent DNA replication
KM415_RS02625	COG0101	tRNA pseudouridine synthase activity
KM415_RS02635	COG3829	transcription factor binding
KM415_RS02645	COG0833	amino acid
KM415_RS02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM415_RS02680	COG1263	PTS System
KM415_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM415_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM415_RS02700	COG0463	Glycosyl transferase, family 2
KM415_RS02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM415_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM415_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM415_RS02745	COG1228	amidohydrolase
KM415_RS02750	COG1090	epimerase
KM415_RS02780	COG1988	membrane-bound metal-dependent
KM415_RS02785	COG1194	a g-specific adenine glycosylase
KM415_RS02810	COG1132	(ABC) transporter
KM415_RS02815	COG4129	membrane
KM415_RS02820	COG0067	glutamate synthase
KM415_RS02820	COG0070	glutamate synthase
KM415_RS02820	COG0069	glutamate synthase activity
KM415_RS02830	COG4555	ABC transporter
KM415_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM415_RS02855	COG0735	belongs to the Fur family
KM415_RS02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM415_RS02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM415_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM415_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM415_RS03005	COG2766	serine protein kinase
KM415_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM415_RS03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM415_RS03040	COG2268	Band 7 protein
KM415_RS03050	COG3290	protein histidine kinase activity
KM415_RS03055	COG4565	transcriptional regulatory protein
KM415_RS03060	COG2851	Citrate transporter
KM415_RS03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM415_RS03085	COG3842	ATPase activity
KM415_RS03090	COG1175	transmembrane transport
KM415_RS03095	COG0395	ABC-type sugar transport system, permease component
KM415_RS03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM415_RS03110	COG0745	RESPONSE REGULATOR receiver
KM415_RS03115	COG5002	protein histidine kinase activity
KM415_RS03125	COG4990	cell redox homeostasis
KM415_RS03135	COG3290	protein histidine kinase activity
KM415_RS03140	COG4565	transcriptional regulatory protein
KM415_RS03145	COG3493	citrate carrier protein
KM415_RS03150	COG0281	malic enzyme
KM415_RS03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS03175	COG5002	protein histidine kinase activity
KM415_RS03180	COG0745	RESPONSE REGULATOR receiver
KM415_RS03185	COG0456	acetyltransferase
KM415_RS03185	COG0454	-acetyltransferase
KM415_RS03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM415_RS03195	COG3383	formate dehydrogenase (NAD+) activity
KM415_RS03215	COG0531	amino acid
KM415_RS03220	COG0640	Transcriptional regulator
KM415_RS03225	COG2217	Heavy metal translocating P-type atpase
KM415_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM415_RS03245	COG3227	Zinc metalloprotease (Elastase)
KM415_RS03265	COG2720	vancomycin resistance protein
KM415_RS03270	COG1316	TRANSCRIPTIONal
KM415_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS03280	COG0346	lactoylglutathione lyase activity
KM415_RS03290	COG1027	Aspartate ammonia-lyase
KM415_RS03295	COG1620	l-lactate permease
KM415_RS03310	COG3104	oligopeptide transport
KM415_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM415_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS03335	COG2226	methyltransferase
KM415_RS03340	COG0156	8-amino-7-oxononanoate synthase activity
KM415_RS03355	COG4548	von Willebrand factor, type A
KM415_RS03360	COG0714	Associated with various cellular activities
KM415_RS03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM415_RS03385	COG0531	amino acid
KM415_RS03390	COG2188	Transcriptional regulator
KM415_RS03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM415_RS03395	COG1263	PTS System
KM415_RS03400	COG0366	Alpha amylase catalytic
KM415_RS03415	COG0697	spore germination
KM415_RS03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM415_RS03430	COG1115	amino acid carrier protein
KM415_RS03435	COG1126	abc transporter atp-binding protein
KM415_RS03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM415_RS03445	COG0765	amino acid transport
KM415_RS03450	COG0765	amino acid transport
KM415_RS03455	COG0833	amino acid
KM415_RS03480	COG2378	regulation of single-species biofilm formation
KM415_RS03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM415_RS03490	COG5002	protein histidine kinase activity
KM415_RS03505	COG0659	secondary active sulfate transmembrane transporter activity
KM415_RS03520	COG0747	negative chemotaxis
KM415_RS03530	COG0601	transmembrane transport
KM415_RS03535	COG4608	Belongs to the ABC transporter superfamily
KM415_RS03545	COG2271	Major facilitator Superfamily
KM415_RS03550	COG1846	Transcriptional regulator
KM415_RS03560	COG1609	Transcriptional regulator
KM415_RS03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM415_RS03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM415_RS03585	COG1879	ABC-type sugar transport system periplasmic component
KM415_RS03610	COG1063	alcohol dehydrogenase
KM415_RS03625	COG3568	Endonuclease Exonuclease Phosphatase
KM415_RS03650	COG1968	undecaprenyl-diphosphatase activity
KM415_RS03655	COG0840	transmembrane signaling receptor activity
KM415_RS03660	COG3584	3D domain protein
KM415_RS03660	COG1388	LysM domain
KM415_RS03665	COG1476	TRANSCRIPTIONal
KM415_RS03680	COG3104	oligopeptide transport
KM415_RS03685	COG1114	Component of the transport system for branched-chain amino acids
KM415_RS03700	COG1113	amino acid transport
KM415_RS03705	COG2252	PERMEase
KM415_RS03730	COG0569	domain protein
KM415_RS03730	COG0475	glutathione-regulated potassium exporter activity
KM415_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM415_RS03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM415_RS03755	COG4990	cell redox homeostasis
KM415_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM415_RS03775	COG0697	spore germination
KM415_RS03780	COG0531	amino acid
KM415_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM415_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM415_RS03800	COG1918	ferrous iron import across plasma membrane
KM415_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM415_RS03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM415_RS03810	COG0573	inorganic phosphate transmembrane transporter activity
KM415_RS03815	COG0581	inorganic phosphate transmembrane transporter activity
KM415_RS03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM415_RS03945	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM415_RS03965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM415_RS03970	COG1116	anion transmembrane transporter activity
KM415_RS03975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM415_RS03980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM415_RS03985	COG0352	thiamine-phosphate diphosphorylase activity
KM415_RS03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM415_RS03995	COG2104	thiamine diphosphate biosynthetic process
KM415_RS04005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM415_RS04010	COG0351	phosphomethylpyrimidine kinase
KM415_RS04050	COG2205	protein histidine kinase activity
KM415_RS04055	COG2814	Major facilitator Superfamily
KM415_RS04060	COG1846	Transcriptional regulator
KM415_RS04075	COG2252	PERMEase
KM415_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM415_RS04100	COG1621	beta-fructofuranosidase activity
KM415_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM415_RS04105	COG1263	PTS System
KM415_RS04110	COG1609	Transcriptional regulator
KM415_RS04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM415_RS04125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM415_RS04160	COG0778	Nitroreductase
KM415_RS04165	COG2719	SpoVR family
KM415_RS04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM415_RS04195	COG1937	Protein conserved in bacteria
KM415_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM415_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
KM415_RS04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM415_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
KM415_RS04225	COG2210	Belongs to the sulfur carrier protein TusA family
KM415_RS04230	COG0730	response to heat
KM415_RS04240	COG1316	TRANSCRIPTIONal
KM415_RS04245	COG0604	alcohol dehydrogenase
KM415_RS04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM415_RS04265	COG3711	transcriptional antiterminator
KM415_RS04265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM415_RS04270	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM415_RS04275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM415_RS04295	COG3584	3D domain protein
KM415_RS04295	COG1388	LysM domain
KM415_RS04300	COG0577	efflux transmembrane transporter activity
KM415_RS04305	COG1136	(ABC) transporter
KM415_RS04315	COG5522	Integral membrane protein (intg_mem_TP0381)
KM415_RS04330	COG1114	Component of the transport system for branched-chain amino acids
KM415_RS04335	COG3546	catalase activity
KM415_RS04370	COG0586	Pfam SNARE associated Golgi protein
KM415_RS04405	COG0531	amino acid
KM415_RS04410	COG0475	glutathione-regulated potassium exporter activity
KM415_RS04420	COG1737	Transcriptional regulator
KM415_RS04430	COG1263	PTS System
KM415_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM415_RS04440	COG2259	Doxx family
KM415_RS04455	COG0697	spore germination
KM415_RS04460	COG1522	sequence-specific DNA binding
KM415_RS04475	COG2076	Multidrug Resistance protein
KM415_RS04480	COG1309	transcriptional regulator
KM415_RS04485	COG2814	Major facilitator Superfamily
KM415_RS04490	COG1733	regulation of RNA biosynthetic process
KM415_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM415_RS04505	COG4533	DNA binding
KM415_RS04510	COG2211	Major facilitator Superfamily
KM415_RS04520	COG0693	protein deglycase activity
KM415_RS04525	COG0753	catalase activity
KM415_RS04525	COG0693	protein deglycase activity
KM415_RS04535	COG0531	amino acid
KM415_RS04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM415_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS04555	COG1132	(ABC) transporter
KM415_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM415_RS04570	COG0765	amino acid transport
KM415_RS04575	COG1126	abc transporter atp-binding protein
KM415_RS04590	COG0189	ligase activity
KM415_RS04620	COG0028	Belongs to the TPP enzyme family
KM415_RS04625	COG3527	Alpha-acetolactate decarboxylase
KM415_RS04640	COG0561	phosphatase activity
KM415_RS04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM415_RS04670	COG0659	secondary active sulfate transmembrane transporter activity
KM415_RS04690	COG0653	protein targeting
KM415_RS04695	COG2244	polysaccharide biosynthetic process
KM415_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM415_RS04710	COG4196	transglutaminase domain protein
KM415_RS04725	COG1696	Membrane protein involved in D-alanine export
KM415_RS04740	COG1024	Enoyl-CoA hydratase
KM415_RS04760	COG1363	Peptidase, m42
KM415_RS04780	COG3938	Belongs to the proline racemase family
KM415_RS04820	COG0601	transmembrane transport
KM415_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM415_RS04835	COG4608	Belongs to the ABC transporter superfamily
KM415_RS04870	COG0477	Major facilitator Superfamily
KM415_RS04875	COG3290	protein histidine kinase activity
KM415_RS04880	COG4565	transcriptional regulatory protein
KM415_RS04885	COG3181	Tripartite tricarboxylate transporter family receptor
KM415_RS04915	COG0789	Transcriptional regulator
KM415_RS04915	COG4978	Transcriptional regulator
KM415_RS04930	COG0305	Participates in initiation and elongation during chromosome replication
KM415_RS04970	COG0477	Major facilitator Superfamily
KM415_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM415_RS05015	COG3320	Male sterility
KM415_RS05020	COG1309	transcriptional regulator
KM415_RS05040	COG1183	phosphatidylcholine synthase activity
KM415_RS05060	COG2376	Dihydroxyacetone kinase
KM415_RS05070	COG2376	Dihydroxyacetone kinase
KM415_RS05075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM415_RS05080	COG1959	2 iron, 2 sulfur cluster binding
KM415_RS05110	COG2770	Histidine kinase
KM415_RS05110	COG3437	response regulator, receiver
KM415_RS05160	COG3237	CsbD-like
KM415_RS05185	COG1191	sigma factor activity
KM415_RS05195	COG2208	phosphoserine phosphatase activity
KM415_RS05200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM415_RS05205	COG2198	Histidine kinase
KM415_RS05205	COG2205	protein histidine kinase activity
KM415_RS05205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM415_RS05205	COG0784	Response regulator, receiver
KM415_RS05260	COG0420	3'-5' exonuclease activity
KM415_RS05285	COG1309	transcriptional regulator
KM415_RS05290	COG2814	Major facilitator Superfamily
KM415_RS05295	COG0346	lactoylglutathione lyase activity
KM415_RS05305	COG0457	Tetratricopeptide repeat
KM415_RS05310	COG2267	carboxylic ester hydrolase activity
KM415_RS05330	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM415_RS05335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM415_RS05345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM415_RS05385	COG0477	Major facilitator Superfamily
KM415_RS05390	COG0477	Major facilitator Superfamily
KM415_RS05400	COG3973	AAA domain
KM415_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM415_RS05425	COG4980	gas vesicle protein
KM415_RS05430	COG0537	adenosine 5'-monophosphoramidase activity
KM415_RS05435	COG1131	(ABC) transporter
KM415_RS05440	COG4473	ABC transporter
KM415_RS05455	COG1309	transcriptional regulator
KM415_RS05465	COG3402	PFAM membrane-flanked domain
KM415_RS05510	COG3402	PFAM membrane-flanked domain
KM415_RS05515	COG3428	Bacterial PH domain
KM415_RS05520	COG2329	Antibiotic biosynthesis monooxygenase
KM415_RS05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM415_RS05530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM415_RS05535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM415_RS05540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM415_RS05575	COG1309	transcriptional regulator
KM415_RS05580	COG1511	domain protein
KM415_RS05605	COG1609	Transcriptional regulator
KM415_RS05615	COG1234	tRNA 3'-trailer cleavage
KM415_RS05620	COG0095	Lipoate-protein ligase
KM415_RS05630	COG0318	PFAM AMP-dependent synthetase and ligase
KM415_RS05660	COG3209	COG3209 Rhs family protein
KM415_RS05700	COG1078	dGTPase activity
KM415_RS05710	COG1595	DNA-templated transcription, initiation
KM415_RS05715	COG3708	Transcriptional regulator
KM415_RS05715	COG2207	Transcriptional regulator
KM415_RS05730	COG2205	protein histidine kinase activity
KM415_RS05735	COG0745	RESPONSE REGULATOR receiver
KM415_RS05760	COG0501	Belongs to the peptidase M48B family
KM415_RS05765	COG0840	transmembrane signaling receptor activity
KM415_RS05770	COG0697	spore germination
KM415_RS05790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM415_RS05795	COG2224	Isocitrate lyase
KM415_RS05820	COG4903	ComK protein
KM415_RS05825	COG0398	Pfam SNARE associated Golgi protein
KM415_RS05835	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM415_RS05840	COG1074	ATP-dependent DNA helicase activity
KM415_RS05885	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM415_RS05910	COG0367	asparagine synthase
KM415_RS05915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM415_RS05920	COG0753	catalase activity
KM415_RS05925	COG0004	ammonium transporteR
KM415_RS05945	COG2996	Protein conserved in bacteria
KM415_RS05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM415_RS05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS05980	COG0561	phosphatase activity
KM415_RS05990	COG0542	response to heat
KM415_RS06000	COG2267	carboxylic ester hydrolase activity
KM415_RS06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM415_RS06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM415_RS06025	COG5504	Zn-dependent protease
KM415_RS06035	COG0180	Tryptophanyl-tRNA synthetase
KM415_RS06045	COG4166	transmembrane transport
KM415_RS06050	COG0601	transmembrane transport
KM415_RS06055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM415_RS06060	COG0444	Belongs to the ABC transporter superfamily
KM415_RS06065	COG4608	Belongs to the ABC transporter superfamily
KM415_RS06070	COG0534	Mate efflux family protein
KM415_RS06075	COG4166	transmembrane transport
KM415_RS06090	COG0861	Integral membrane protein TerC family
KM415_RS06095	COG4862	establishment of competence for transformation
KM415_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM415_RS06110	COG1164	Oligoendopeptidase f
KM415_RS06120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM415_RS06125	COG2346	COG2346, Truncated hemoglobins
KM415_RS06130	COG4116	CYTH
KM415_RS06140	COG2357	RelA SpoT domain protein
KM415_RS06150	COG0564	pseudouridine synthase activity
KM415_RS06170	COG1216	Glycosyl transferase, family 2
KM415_RS06170	COG0463	Glycosyl transferase, family 2
KM415_RS06190	COG0457	Tetratricopeptide repeat
KM415_RS06190	COG0463	Glycosyl transferase, family 2
KM415_RS06210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM415_RS06225	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM415_RS06270	COG2153	protein acetylation
KM415_RS06280	COG2382	esterase
KM415_RS06295	COG5492	domain, Protein
KM415_RS06300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM415_RS06310	COG0512	Glutamine amidotransferase of anthranilate synthase
KM415_RS06310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM415_RS06345	COG1620	l-lactate permease
KM415_RS06350	COG5634	Uncharacterized conserved protein (DUF2278)
KM415_RS06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM415_RS06415	COG1476	TRANSCRIPTIONal
KM415_RS06475	COG2226	methyltransferase
KM415_RS06485	COG1686	Belongs to the peptidase S11 family
KM415_RS06490	COG0681	Belongs to the peptidase S26 family
KM415_RS06525	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS06530	COG3842	ATPase activity
KM415_RS06535	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM415_RS06540	COG1177	transmembrane transport
KM415_RS06545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM415_RS06555	COG2409	Drug exporters of the RND superfamily
KM415_RS06565	COG0564	pseudouridine synthase activity
KM415_RS06575	COG2340	Cysteine-rich secretory protein family
KM415_RS06580	COG0247	lactate metabolic process
KM415_RS06585	COG0277	FAD linked oxidase domain protein
KM415_RS06590	COG3835	regulator
KM415_RS06600	COG0745	RESPONSE REGULATOR receiver
KM415_RS06605	COG5002	protein histidine kinase activity
KM415_RS06610	COG2186	Transcriptional regulator
KM415_RS06630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM415_RS06640	COG2116	formate transmembrane transporter activity
KM415_RS06645	COG0861	Integral membrane protein TerC family
KM415_RS06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM415_RS06660	COG2030	dehydratase
KM415_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS06685	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM415_RS06690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM415_RS06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM415_RS06710	COG1840	ABC-type Fe3 transport system, periplasmic component
KM415_RS06740	COG1349	DNA-binding transcription factor activity
KM415_RS06760	COG2861	carbohydrate metabolic process
KM415_RS06770	COG3852	Histidine kinase
KM415_RS06775	COG1846	Transcriptional regulator
KM415_RS06785	COG2318	DinB family
KM415_RS06795	COG5002	protein histidine kinase activity
KM415_RS06805	COG0720	synthase
KM415_RS06820	COG4873	Protein conserved in bacteria
KM415_RS06850	COG1780	Probably involved in ribonucleotide reductase function
KM415_RS06870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM415_RS06875	COG1725	Transcriptional regulator
KM415_RS06880	COG1131	(ABC) transporter
KM415_RS06890	COG1131	(ABC) transporter
KM415_RS06895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM415_RS06910	COG1522	sequence-specific DNA binding
KM415_RS06920	COG1335	isochorismatase
KM415_RS06930	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM415_RS06935	COG2070	2-Nitropropane dioxygenase
KM415_RS06940	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM415_RS06950	COG1696	Membrane protein involved in D-alanine export
KM415_RS06975	COG0716	FMN binding
KM415_RS06990	COG3173	Aminoglycoside phosphotransferase
KM415_RS07010	COG0534	Mate efflux family protein
KM415_RS07015	COG1968	undecaprenyl-diphosphatase activity
KM415_RS07030	COG1846	Transcriptional regulator
KM415_RS07040	COG1301	dicarboxylic acid transport
KM415_RS07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM415_RS07050	COG4709	membrane
KM415_RS07055	COG3874	Sporulation protein YtfJ
KM415_RS07080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM415_RS07085	COG0028	Belongs to the TPP enzyme family
KM415_RS07090	COG0440	acetolactate synthase activity
KM415_RS07095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM415_RS07105	COG0473	3-isopropylmalate dehydrogenase activity
KM415_RS07130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM415_RS07165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM415_RS07180	COG1183	phosphatidylcholine synthase activity
KM415_RS07185	COG1368	sulfuric ester hydrolase activity
KM415_RS07195	COG0019	diaminopimelate decarboxylase activity
KM415_RS07215	COG0529	Catalyzes the synthesis of activated sulfate
KM415_RS07220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM415_RS07240	COG1648	precorrin-2 dehydrogenase activity
KM415_RS07245	COG0733	neurotransmitter:sodium symporter activity
KM415_RS07265	COG1757	Na H antiporter
KM415_RS07280	COG4758	membrane
KM415_RS07285	COG4585	Histidine kinase
KM415_RS07290	COG2197	response regulator
KM415_RS07300	COG1114	Component of the transport system for branched-chain amino acids
KM415_RS07310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM415_RS07335	COG1017	nitric oxide dioxygenase activity
KM415_RS07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM415_RS07350	COG0730	response to heat
KM415_RS07355	COG0306	phosphate transporter
KM415_RS07360	COG1392	Phosphate transport regulator
KM415_RS07365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM415_RS07380	COG3852	Histidine kinase
KM415_RS07385	COG1801	Protein of unknown function DUF72
KM415_RS07395	COG0582	viral genome integration into host DNA
KM415_RS07400	COG5002	protein histidine kinase activity
KM415_RS07420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM415_RS07420	COG0392	lysyltransferase activity
KM415_RS07435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM415_RS07440	COG1686	Belongs to the peptidase S11 family
KM415_RS07445	COG2715	membrane protein required for spore maturation
KM415_RS07450	COG0700	Nucleoside recognition
KM415_RS07455	COG1187	pseudouridine synthase activity
KM415_RS07465	COG1333	cytochrome c biogenesis protein
KM415_RS07470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM415_RS07475	COG0745	RESPONSE REGULATOR receiver
KM415_RS07480	COG5002	protein histidine kinase activity
KM415_RS07485	COG2096	Adenosyltransferase
KM415_RS07500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM415_RS07505	COG1141	Ferredoxin
KM415_RS07510	COG4955	Helix-turn-helix domain
KM415_RS07515	COG0514	ATP-dependent DNA helicase (RecQ)
KM415_RS07520	COG1266	CAAX protease self-immunity
KM415_RS07540	COG4862	establishment of competence for transformation
KM415_RS07545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM415_RS07565	COG0492	ferredoxin-NADP+ reductase activity
KM415_RS07570	COG0252	asparaginase activity
KM415_RS07640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM415_RS07655	COG0142	geranyltranstransferase activity
KM415_RS07665	COG0142	geranyltranstransferase activity
KM415_RS07685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM415_RS07690	COG0457	Tetratricopeptide repeat
KM415_RS07710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM415_RS07720	COG4347	Protein of unknown function (DUF1405)
KM415_RS07735	COG2738	Putative neutral zinc metallopeptidase
KM415_RS07745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS07750	COG1694	Mazg nucleotide pyrophosphohydrolase
KM415_RS07765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM415_RS07770	COG0438	transferase activity, transferring glycosyl groups
KM415_RS07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM415_RS07805	COG1199	ATP-dependent helicase activity
KM415_RS07825	COG3935	DnaD domain protein
KM415_RS07830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM415_RS07840	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM415_RS07840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM415_RS07900	COG0116	Belongs to the methyltransferase superfamily
KM415_RS07910	COG1199	ATP-dependent helicase activity
KM415_RS07915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM415_RS07925	COG3173	Aminoglycoside phosphotransferase
KM415_RS07930	COG0024	Methionine aminopeptidase
KM415_RS07940	COG2233	PERMEase
KM415_RS07945	COG2311	Membrane
KM415_RS07950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM415_RS07960	COG0456	acetyltransferase
KM415_RS08010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM415_RS08035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM415_RS08050	COG1215	transferase activity, transferring glycosyl groups
KM415_RS08055	COG0438	transferase activity, transferring glycosyl groups
KM415_RS08070	COG0454	-acetyltransferase
KM415_RS08090	COG0328	RNA-DNA hybrid ribonuclease activity
KM415_RS08130	COG1280	lysine exporter protein (LysE YggA)
KM415_RS08145	COG3162	membrane
KM415_RS08150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM415_RS08155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM415_RS08165	COG0475	glutathione-regulated potassium exporter activity
KM415_RS08170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM415_RS08175	COG0789	Transcriptional regulator
KM415_RS08175	COG4978	Transcriptional regulator
KM415_RS08185	COG2323	membrane
KM415_RS08190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM415_RS08245	COG1923	regulation of RNA biosynthetic process
KM415_RS08255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM415_RS08260	COG1360	Flagellar Motor Protein
KM415_RS08265	COG2201	protein-glutamate methylesterase activity
KM415_RS08275	COG1776	CheC inhibitor of MCP methylation
KM415_RS08275	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM415_RS08290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM415_RS08310	COG1256	bacterial-type flagellum assembly
KM415_RS08335	COG1815	bacterial-type flagellum-dependent cell motility
KM415_RS08340	COG1558	bacterial-type flagellum-dependent cell motility
KM415_RS08355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM415_RS08365	COG1157	protein secretion by the type III secretion system
KM415_RS08400	COG0784	Response regulator, receiver
KM415_RS08400	COG0835	chemotaxis
KM415_RS08410	COG0463	Glycosyl transferase, family 2
KM415_RS08435	COG0457	Tetratricopeptide repeat
KM415_RS08435	COG0463	Glycosyl transferase, family 2
KM415_RS08450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM415_RS08455	COG0741	lytic transglycosylase activity
KM415_RS08470	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM415_RS08470	COG1776	CheC inhibitor of MCP methylation
KM415_RS08480	COG1338	Plays a role in the flagellum-specific transport system
KM415_RS08485	COG1987	bacterial-type flagellum assembly
KM415_RS08495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM415_RS08500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM415_RS08505	COG1419	protein localization to endoplasmic reticulum
KM415_RS08510	COG4786	Flagellar basal body rod
KM415_RS08515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM415_RS08540	COG1309	transcriptional regulator
KM415_RS08560	COG2329	Antibiotic biosynthesis monooxygenase
KM415_RS08585	COG0583	DNA-binding transcription factor activity
KM415_RS08595	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM415_RS08605	COG1234	tRNA 3'-trailer cleavage
KM415_RS08630	COG1686	Belongs to the peptidase S11 family
KM415_RS08640	COG0406	alpha-ribazole phosphatase activity
KM415_RS08670	COG0367	asparagine synthase
KM415_RS08700	COG1802	Transcriptional regulator
KM415_RS08705	COG0697	spore germination
KM415_RS08710	COG0523	cobalamin synthesis protein
KM415_RS08715	COG0701	Predicted permease
KM415_RS08725	COG0438	transferase activity, transferring glycosyl groups
KM415_RS08725	COG1216	Glycosyl transferase, family 2
KM415_RS08730	COG1757	Na H antiporter
KM415_RS08735	COG0114	fumarate hydratase activity
KM415_RS08760	COG3340	Belongs to the peptidase S51 family
KM415_RS08780	COG0785	Cytochrome C biogenesis protein
KM415_RS08810	COG2733	membrane
KM415_RS08845	COG1131	(ABC) transporter
KM415_RS08860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM415_RS08865	COG0528	UMP kinase activity
KM415_RS08875	COG1027	Aspartate ammonia-lyase
KM415_RS08880	COG0281	malic enzyme
KM415_RS08885	COG4191	Histidine kinase
KM415_RS08890	COG0784	Response regulator, receiver
KM415_RS08895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM415_RS08955	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM415_RS08965	COG2814	Major facilitator Superfamily
KM415_RS08980	COG1966	Carbon starvation protein
KM415_RS08995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM415_RS09005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM415_RS09015	COG2223	nitrite transmembrane transporter activity
KM415_RS09020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM415_RS09035	COG2244	polysaccharide biosynthetic process
KM415_RS09040	COG0733	neurotransmitter:sodium symporter activity
KM415_RS09050	COG5566	PFAM Mor transcription activator
KM415_RS09055	COG2323	membrane
KM415_RS09075	COG2084	Dehydrogenase
KM415_RS09090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM415_RS09100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM415_RS09105	COG0028	Belongs to the TPP enzyme family
KM415_RS09110	COG0440	acetolactate synthase activity
KM415_RS09115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM415_RS09125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM415_RS09150	COG2814	Major facilitator Superfamily
KM415_RS09155	COG3384	dioxygenase
KM415_RS09165	COG3279	Response regulator of the LytR AlgR family
KM415_RS09170	COG0427	acetyl-CoA hydrolase
KM415_RS09190	COG1073	alpha beta
KM415_RS09220	COG0535	radical SAM domain protein
KM415_RS09225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS09245	COG1914	H( )-stimulated, divalent metal cation uptake system
KM415_RS09260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM415_RS09290	COG2390	Transcriptional regulator
KM415_RS09300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS09305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM415_RS09320	COG4224	UPF0291 protein
KM415_RS09340	COG0006	proline dipeptidase activity
KM415_RS09345	COG2132	Multicopper oxidase
KM415_RS09360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM415_RS09375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM415_RS09390	COG1276	copper resistance
KM415_RS09390	COG2372	response to copper ion
KM415_RS09395	COG4549	nuclear export factor GLE1
KM415_RS09405	COG0697	spore germination
KM415_RS09410	COG0583	DNA-binding transcription factor activity
KM415_RS09415	COG1959	2 iron, 2 sulfur cluster binding
KM415_RS09420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM415_RS09425	COG0778	Nitroreductase
KM415_RS09435	COG0628	permease
KM415_RS09445	COG1231	oxidoreductase activity
KM415_RS09450	COG0523	cobalamin synthesis protein
KM415_RS09470	COG2030	dehydratase
KM415_RS09475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM415_RS09485	COG0411	ABC transporter
KM415_RS09505	COG0583	DNA-binding transcription factor activity
KM415_RS09515	COG1942	4-Oxalocrotonate Tautomerase
KM415_RS09525	COG1846	Transcriptional regulator
KM415_RS09535	COG1271	oxidase subunit
KM415_RS09540	COG1294	oxidase, subunit
KM415_RS09545	COG4988	ABC transporter
KM415_RS09550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM415_RS09570	COG1686	Belongs to the peptidase S11 family
KM415_RS09585	COG1388	LysM domain
KM415_RS09585	COG0791	NLP P60 protein
KM415_RS09600	COG0745	RESPONSE REGULATOR receiver
KM415_RS09605	COG5002	protein histidine kinase activity
KM415_RS09615	COG0300	oxidoreductase activity
KM415_RS09650	COG0460	homoserine dehydrogenase
KM415_RS09675	COG1316	TRANSCRIPTIONal
KM415_RS09685	COG0745	RESPONSE REGULATOR receiver
KM415_RS09690	COG5002	protein histidine kinase activity
KM415_RS09705	COG1285	pathogenesis
KM415_RS09710	COG1247	-acetyltransferase
KM415_RS09730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM415_RS09740	COG1082	Xylose isomerase domain protein TIM barrel
KM415_RS09755	COG1279	arginine transmembrane transporter activity
KM415_RS09765	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM415_RS09805	COG2002	toxin-antitoxin pair type II binding
KM415_RS09810	COG1404	Belongs to the peptidase S8 family
KM415_RS09815	COG0640	Transcriptional regulator
KM415_RS09820	COG0667	Aldo Keto reductase
KM415_RS09825	COG2814	Major facilitator Superfamily
KM415_RS09850	COG0840	transmembrane signaling receptor activity
KM415_RS09865	COG3949	Membrane
KM415_RS09870	COG0783	Belongs to the Dps family
KM415_RS09885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM415_RS09895	COG1231	oxidoreductase activity
KM415_RS09905	COG4989	oxidoreductase activity
KM415_RS09910	COG0523	cobalamin synthesis protein
KM415_RS09915	COG0456	acetyltransferase
KM415_RS09975	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM415_RS09975	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM415_RS09985	COG0702	epimerase
KM415_RS09995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM415_RS10005	COG4166	transmembrane transport
KM415_RS10020	COG0406	alpha-ribazole phosphatase activity
KM415_RS10030	COG5337	Spore coat protein CotH
KM415_RS10035	COG1051	belongs to the nudix hydrolase family
KM415_RS10040	COG0586	Pfam SNARE associated Golgi protein
KM415_RS10045	COG2244	polysaccharide biosynthetic process
KM415_RS10055	COG0701	Predicted permease
KM415_RS10060	COG3689	TIGRFAM TIGR03943 family protein
KM415_RS10065	COG1607	acyl-coa hydrolase
KM415_RS10090	COG0702	epimerase
KM415_RS10095	COG2839	Protein conserved in bacteria
KM415_RS10100	COG1253	flavin adenine dinucleotide binding
KM415_RS10115	COG1114	Component of the transport system for branched-chain amino acids
KM415_RS10120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM415_RS10140	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM415_RS10150	COG1876	peptidase activity
KM415_RS10160	COG0154	amidase activity
KM415_RS10165	COG2211	Major facilitator Superfamily
KM415_RS10185	COG0561	phosphatase activity
KM415_RS10195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM415_RS10200	COG4106	trans-aconitate 2-methyltransferase activity
KM415_RS10215	COG1819	glycosyl
KM415_RS10220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS10225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS10260	COG0456	acetyltransferase
KM415_RS10315	COG3874	Sporulation protein YtfJ
KM415_RS10340	COG2226	methyltransferase
KM415_RS10365	COG0346	lactoylglutathione lyase activity
KM415_RS10375	COG0604	alcohol dehydrogenase
KM415_RS10380	COG1595	DNA-templated transcription, initiation
KM415_RS10405	COG0386	Belongs to the glutathione peroxidase family
KM415_RS10410	COG1305	Transglutaminase-like
KM415_RS10415	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM415_RS10420	COG0714	Associated with various cellular activities
KM415_RS10435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM415_RS10440	COG1140	nitrate reductase beta subunit
KM415_RS10445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM415_RS10450	COG2181	nitrate reductase activity
KM415_RS10470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM415_RS10475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM415_RS10480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM415_RS10485	COG0303	'Molybdopterin
KM415_RS10490	COG0314	molybdopterin synthase activity
KM415_RS10500	COG2223	nitrite transmembrane transporter activity
KM415_RS10515	COG1648	precorrin-2 dehydrogenase activity
KM415_RS10525	COG1587	Uroporphyrinogen-III synthase
KM415_RS10525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM415_RS10530	COG2146	nitrite reductase [NAD(P)H] activity
KM415_RS10535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM415_RS10540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM415_RS10575	COG2359	stage V sporulation protein S
KM415_RS10600	COG1418	mRNA catabolic process
KM415_RS10605	COG0488	(ABC) transporter
KM415_RS10620	COG0629	single-stranded DNA binding
KM415_RS10635	COG1413	lyase activity
KM415_RS10650	COG2136	Putative SAM-dependent methyltransferase
KM415_RS10650	COG2521	methyltransferase
KM415_RS10655	COG0018	arginyl-trna synthetase
KM415_RS10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM415_RS10700	COG0017	Asparaginyl-tRNA synthetase
KM415_RS10720	COG1674	ftsk spoiiie
KM415_RS10790	COG1929	Belongs to the glycerate kinase type-1 family
KM415_RS10795	COG0471	metal ion transport
KM415_RS10800	COG0745	RESPONSE REGULATOR receiver
KM415_RS10805	COG5002	protein histidine kinase activity
KM415_RS10805	COG3850	Histidine kinase
KM415_RS10820	COG0733	neurotransmitter:sodium symporter activity
KM415_RS10845	COG2610	gluconate transmembrane transporter activity
KM415_RS10850	COG1454	alcohol dehydrogenase
KM415_RS10855	COG1794	racemase activity, acting on amino acids and derivatives
KM415_RS10865	COG0456	acetyltransferase
KM415_RS10880	COG1131	(ABC) transporter
KM415_RS10895	COG0546	phosphoglycolate phosphatase activity
KM415_RS10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM415_RS10930	COG0768	penicillin binding
KM415_RS10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM415_RS10940	COG0204	Acyl-transferase
KM415_RS10945	COG1272	protein, Hemolysin III
KM415_RS10955	COG0805	protein transport
KM415_RS10965	COG1307	EDD domain protein, DegV family
KM415_RS10970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM415_RS10975	COG1999	signal sequence binding
KM415_RS10980	COG0071	Belongs to the small heat shock protein (HSP20) family
KM415_RS10985	COG0367	asparagine synthase
KM415_RS11000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM415_RS11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM415_RS11040	COG0668	transmembrane transport
KM415_RS11045	COG4585	Histidine kinase
KM415_RS11045	COG2203	Gaf domain
KM415_RS11050	COG2197	response regulator
KM415_RS11060	COG1064	alcohol dehydrogenase
KM415_RS11115	COG1125	glycine betaine transport
KM415_RS11115	COG0517	IMP dehydrogenase activity
KM415_RS11120	COG1174	glycine betaine transport
KM415_RS11155	COG1253	flavin adenine dinucleotide binding
KM415_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS11165	COG5506	Protein of unknown function (DUF1694)
KM415_RS11180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM415_RS11185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM415_RS11190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM415_RS11195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM415_RS11200	COG0456	acetyltransferase
KM415_RS11205	COG3829	transcription factor binding
KM415_RS11210	COG1509	lysine 2,3-aminomutase activity
KM415_RS11250	COG4326	sporulation control protein
KM415_RS11255	COG0671	phosphoesterase, PA-phosphatase related
KM415_RS11260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM415_RS11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM415_RS11295	COG1715	Restriction endonuclease
KM415_RS11295	COG1787	Restriction endonuclease
KM415_RS11385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM415_RS11425	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM415_RS11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM415_RS11435	COG2814	Major facilitator Superfamily
KM415_RS11440	COG4841	protein insertion into membrane
KM415_RS11445	COG0372	Belongs to the citrate synthase family
KM415_RS11450	COG2079	MmgE PrpD family protein
KM415_RS11455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM415_RS11460	COG1960	acyl-CoA dehydrogenase activity
KM415_RS11465	COG2084	Dehydrogenase
KM415_RS11475	COG1280	lysine exporter protein (LysE YggA)
KM415_RS11480	COG1024	Enoyl-CoA hydratase
KM415_RS11495	COG0420	3'-5' exonuclease activity
KM415_RS11500	COG0419	ATPase involved in DNA repair
KM415_RS11520	COG2223	nitrite transmembrane transporter activity
KM415_RS11525	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS11530	COG1169	isochorismate synthase
KM415_RS11535	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM415_RS11540	COG3433	isochorismatase activity
KM415_RS11540	COG1535	isochorismatase
KM415_RS11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM415_RS11550	COG3251	PFAM MbtH domain protein
KM415_RS11555	COG2814	Major facilitator Superfamily
KM415_RS11570	COG0776	regulation of translation
KM415_RS11580	COG2318	DinB family
KM415_RS11590	COG1115	amino acid carrier protein
KM415_RS11605	COG2329	Antibiotic biosynthesis monooxygenase
KM415_RS11610	COG1187	pseudouridine synthase activity
KM415_RS11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM415_RS11630	COG0596	Alpha beta hydrolase
KM415_RS11635	COG2814	Major facilitator Superfamily
KM415_RS11655	COG2226	methyltransferase
KM415_RS11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS11735	COG1247	-acetyltransferase
KM415_RS11765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM415_RS11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS11785	COG1278	Cold shock
KM415_RS11800	COG0010	Belongs to the arginase family
KM415_RS11805	COG0561	phosphatase activity
KM415_RS11845	COG0583	DNA-binding transcription factor activity
KM415_RS11850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM415_RS11865	COG0583	DNA-binding transcription factor activity
KM415_RS11870	COG2258	MOSC domain
KM415_RS11885	COG1132	(ABC) transporter
KM415_RS11890	COG1132	(ABC) transporter
KM415_RS11910	COG1396	sequence-specific DNA binding
KM415_RS11935	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM415_RS11940	COG1595	DNA-templated transcription, initiation
KM415_RS11965	COG1649	PFAM Uncharacterised BCR, COG1649
KM415_RS11990	COG2971	BadF BadG BcrA BcrD
KM415_RS11995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM415_RS12000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM415_RS12020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS12050	COG1309	transcriptional regulator
KM415_RS12065	COG1136	(ABC) transporter
KM415_RS12065	COG0577	efflux transmembrane transporter activity
KM415_RS12070	COG3615	Tellurite resistance protein tehB
KM415_RS12070	COG0500	methyltransferase
KM415_RS12080	COG2226	methyltransferase
KM415_RS12085	COG3961	Belongs to the TPP enzyme family
KM415_RS12090	COG1846	Transcriptional regulator
KM415_RS12130	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM415_RS12145	COG1595	DNA-templated transcription, initiation
KM415_RS12155	COG0768	penicillin binding
KM415_RS12165	COG2367	Beta-lactamase
KM415_RS12170	COG0671	phosphoesterase, PA-phosphatase related
KM415_RS12175	COG1609	Transcriptional regulator
KM415_RS12180	COG2814	Major facilitator Superfamily
KM415_RS12185	COG0673	inositol 2-dehydrogenase activity
KM415_RS12195	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS12210	COG0191	fructose-bisphosphate aldolase activity
KM415_RS12215	COG3718	enzyme involved in inositol metabolism
KM415_RS12240	COG0457	Tetratricopeptide repeat
KM415_RS12245	COG1476	TRANSCRIPTIONal
KM415_RS12260	COG1876	peptidase activity
KM415_RS12280	COG1309	transcriptional regulator
KM415_RS12285	COG0488	(ABC) transporter
KM415_RS12300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS12315	COG1252	NADH dehydrogenase
KM415_RS12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM415_RS12335	COG1131	(ABC) transporter
KM415_RS12345	COG1309	transcriptional regulator
KM415_RS12360	COG1960	acyl-CoA dehydrogenase activity
KM415_RS12365	COG0439	Biotin carboxylase
KM415_RS12370	COG0511	ligase activity, forming carbon-carbon bonds
KM415_RS12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM415_RS12380	COG1024	Enoyl-CoA hydratase
KM415_RS12385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM415_RS12390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM415_RS12400	COG1247	-acetyltransferase
KM415_RS12405	COG0572	uridine kinase
KM415_RS12415	COG2318	DinB family
KM415_RS12420	COG1686	Belongs to the peptidase S11 family
KM415_RS12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM415_RS12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM415_RS12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM415_RS12510	COG2814	Major facilitator Superfamily
KM415_RS12530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM415_RS12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS12565	COG1063	alcohol dehydrogenase
KM415_RS12580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM415_RS12585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM415_RS12600	COG3773	Cell wall hydrolase
KM415_RS12610	COG0745	RESPONSE REGULATOR receiver
KM415_RS12625	COG0488	(ABC) transporter
KM415_RS12640	COG1136	(ABC) transporter
KM415_RS12665	COG0460	homoserine dehydrogenase
KM415_RS12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS12680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM415_RS12745	COG2124	cytochrome p450
KM415_RS12780	COG0561	phosphatase activity
KM415_RS12790	COG0768	penicillin binding
KM415_RS12795	COG1819	glycosyl
KM415_RS12800	COG1794	racemase activity, acting on amino acids and derivatives
KM415_RS12810	COG1122	ATPase activity
KM415_RS12825	COG2205	protein histidine kinase activity
KM415_RS12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM415_RS12840	COG0604	alcohol dehydrogenase
KM415_RS12845	COG0768	penicillin binding
KM415_RS12855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM415_RS12890	COG0693	protein deglycase activity
KM415_RS12920	COG2814	Major facilitator Superfamily
KM415_RS12935	COG0584	glycerophosphoryl diester phosphodiesterase
KM415_RS12955	COG0697	spore germination
KM415_RS12985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM415_RS12995	COG2223	nitrite transmembrane transporter activity
KM415_RS13010	COG2816	NAD+ diphosphatase activity
KM415_RS13015	COG0592	DNA-directed DNA polymerase activity
KM415_RS13020	COG1051	belongs to the nudix hydrolase family
KM415_RS13055	COG3878	Protein conserved in bacteria
KM415_RS13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM415_RS13120	COG0322	excinuclease ABC activity
KM415_RS13160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM415_RS13185	COG1011	Hydrolase
KM415_RS13205	COG0076	glutamate decarboxylase activity
KM415_RS13220	COG1523	belongs to the glycosyl hydrolase 13 family
KM415_RS13225	COG3227	Zinc metalloprotease (Elastase)
KM415_RS13245	COG0201	protein transport
KM415_RS13255	COG0697	spore germination
KM415_RS13260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS13290	COG4129	membrane
KM415_RS13295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS13310	COG2959	enzyme of heme biosynthesis
KM415_RS13330	COG3483	tryptophan 2,3-dioxygenase activity
KM415_RS13335	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM415_RS13340	COG3844	kynureninase activity
KM415_RS13345	COG1309	transcriptional regulator
KM415_RS13375	COG3284	Transcriptional regulator
KM415_RS13395	COG1349	DNA-binding transcription factor activity
KM415_RS13415	COG1959	2 iron, 2 sulfur cluster binding
KM415_RS13430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM415_RS13435	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM415_RS13440	COG0022	dehydrogenase e1 component
KM415_RS13445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM415_RS13455	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS13460	COG0456	acetyltransferase
KM415_RS13460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM415_RS13490	COG4176	ABC-type proline glycine betaine transport system permease component
KM415_RS13495	COG0517	IMP dehydrogenase activity
KM415_RS13495	COG4175	Glycine betaine
KM415_RS13520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM415_RS13525	COG2153	protein acetylation
KM415_RS13530	COG3397	chitin binding
KM415_RS13545	COG2205	protein histidine kinase activity
KM415_RS13570	COG0658	competence protein
KM415_RS13570	COG2333	competence protein COMEC
KM415_RS13620	COG3973	AAA domain
KM415_RS13635	COG2105	PFAM AIG2 family protein
KM415_RS13640	COG0514	ATP-dependent DNA helicase (RecQ)
KM415_RS13660	COG4637	Psort location Cytoplasmic, score
KM415_RS13685	COG3397	chitin binding
KM415_RS13700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM415_RS13705	COG1115	amino acid carrier protein
KM415_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS13715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM415_RS13725	COG3938	Belongs to the proline racemase family
KM415_RS13730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM415_RS13770	COG0586	Pfam SNARE associated Golgi protein
KM415_RS13785	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM415_RS13790	COG0519	Catalyzes the synthesis of GMP from XMP
KM415_RS13795	COG4166	transmembrane transport
KM415_RS13805	COG4948	Mandelate Racemase Muconate Lactonizing
KM415_RS13850	COG2936	dipeptidyl-peptidase activity
KM415_RS13855	COG5002	protein histidine kinase activity
KM415_RS13905	COG1307	EDD domain protein, DegV family
KM415_RS13925	COG2814	Major facilitator Superfamily
KM415_RS13935	COG1664	Polymer-forming cytoskeletal
KM415_RS13940	COG0789	Transcriptional regulator
KM415_RS13945	COG4533	DNA binding
KM415_RS13950	COG2814	Major facilitator Superfamily
KM415_RS13950	COG0477	Major facilitator Superfamily
KM415_RS13970	COG2261	transglycosylase associated protein
KM415_RS13985	COG2226	methyltransferase
KM415_RS14020	COG0436	Aminotransferase
KM415_RS14025	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM415_RS14030	COG5146	pantothenate kinase activity
KM415_RS14050	COG1131	(ABC) transporter
KM415_RS14095	COG0628	permease
KM415_RS14110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM415_RS14115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM415_RS14120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM415_RS14125	COG1116	anion transmembrane transporter activity
KM415_RS14145	COG2816	NAD+ diphosphatase activity
KM415_RS14165	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM415_RS14190	COG0697	spore germination
KM415_RS14195	COG2318	DinB family
KM415_RS14215	COG4912	Dna alkylation repair
KM415_RS14235	COG0861	Integral membrane protein TerC family
KM415_RS14240	COG1368	sulfuric ester hydrolase activity
KM415_RS14245	COG0488	(ABC) transporter
KM415_RS14260	COG1309	transcriptional regulator
KM415_RS14275	COG0287	Prephenate dehydrogenase
KM415_RS14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM415_RS14285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM415_RS14290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM415_RS14290	COG1605	Chorismate mutase
KM415_RS14325	COG1388	LysM domain
KM415_RS14325	COG3584	3D domain protein
KM415_RS14335	COG1595	DNA-templated transcription, initiation
KM415_RS14360	COG1879	ABC-type sugar transport system periplasmic component
KM415_RS14370	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM415_RS14380	COG2390	Transcriptional regulator
KM415_RS14415	COG2329	Antibiotic biosynthesis monooxygenase
KM415_RS14435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS14445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM415_RS14450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM415_RS14455	COG4187	Peptidase family M20/M25/M40
KM415_RS14460	COG1414	Transcriptional regulator
KM415_RS14465	COG0833	amino acid
KM415_RS14470	COG1690	Belongs to the RtcB family
KM415_RS14480	COG1785	Belongs to the alkaline phosphatase family
KM415_RS14490	COG3655	Transcriptional regulator
KM415_RS14505	COG4377	Putative membrane peptidase family (DUF2324)
KM415_RS14515	COG3279	Response regulator of the LytR AlgR family
KM415_RS14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS14530	COG0346	lactoylglutathione lyase activity
KM415_RS14550	COG0714	Associated with various cellular activities
KM415_RS14575	COG0463	Glycosyl transferase, family 2
KM415_RS14595	COG0463	Glycosyl transferase, family 2
KM415_RS14605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM415_RS14610	COG0753	catalase activity
KM415_RS14620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM415_RS14645	COG0714	Associated with various cellular activities
KM415_RS14655	COG0778	Nitroreductase
KM415_RS14660	COG1846	Transcriptional regulator
KM415_RS14695	COG1725	Transcriptional regulator
KM415_RS14705	COG1136	(ABC) transporter
KM415_RS14705	COG0577	efflux transmembrane transporter activity
KM415_RS14730	COG2207	Transcriptional regulator
KM415_RS14735	COG0456	acetyltransferase
KM415_RS14755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS14775	COG0642	Histidine kinase
KM415_RS14780	COG0745	RESPONSE REGULATOR receiver
KM415_RS14785	COG0596	Alpha beta hydrolase
KM415_RS14815	COG0730	response to heat
KM415_RS14825	COG0833	amino acid
KM415_RS14835	COG4335	DNA alkylation repair
KM415_RS14875	COG0768	penicillin binding
KM415_RS14885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM415_RS14920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM415_RS14925	COG1414	Transcriptional regulator
KM415_RS14940	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM415_RS14945	COG0640	Transcriptional regulator
KM415_RS14955	COG1960	acyl-CoA dehydrogenase activity
KM415_RS14970	COG3314	Sporulation integral membrane protein YlbJ
KM415_RS14985	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM415_RS15000	COG0574	Belongs to the PEP-utilizing enzyme family
KM415_RS15000	COG3848	Pyruvate phosphate dikinase
KM415_RS15005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS15020	COG5577	PFAM Coat F domain
KM415_RS15025	COG3403	YqcI/YcgG family
KM415_RS15030	COG1280	lysine exporter protein (LysE YggA)
KM415_RS15065	COG1063	alcohol dehydrogenase
KM415_RS15080	COG1027	Aspartate ammonia-lyase
KM415_RS15085	COG0252	asparaginase activity
KM415_RS15090	COG1396	sequence-specific DNA binding
KM415_RS15100	COG0322	excinuclease ABC activity
KM415_RS15105	COG0531	amino acid
KM415_RS15110	COG1114	Component of the transport system for branched-chain amino acids
KM415_RS15115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM415_RS15125	COG0281	malic enzyme
KM415_RS15140	COG0531	amino acid
KM415_RS15150	COG0784	Response regulator, receiver
KM415_RS15160	COG2066	Belongs to the glutaminase family
KM415_RS15165	COG1115	amino acid carrier protein
KM415_RS15195	COG0737	Belongs to the 5'-nucleotidase family
KM415_RS15200	COG0753	catalase activity
KM415_RS15205	COG2267	carboxylic ester hydrolase activity
KM415_RS15210	COG1335	isochorismatase
KM415_RS15230	COG0583	DNA-binding transcription factor activity
KM415_RS15280	COG0415	Belongs to the DNA photolyase family
KM415_RS15285	COG0288	reversible hydration of carbon dioxide
KM415_RS15295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM415_RS15300	COG5609	conserved protein (DUF2294)
KM415_RS15315	COG1575	Belongs to the MenA family. Type 1 subfamily
KM415_RS15320	COG2267	carboxylic ester hydrolase activity
KM415_RS15325	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM415_RS15330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM415_RS15335	COG1121	(ABC) transporter
KM415_RS15365	COG0798	PFAM Bile acid sodium symporter
KM415_RS15370	COG0346	lactoylglutathione lyase activity
KM415_RS15375	COG0640	Transcriptional regulator
KM415_RS15390	COG0443	Heat shock 70 kDa protein
KM415_RS15405	COG1522	sequence-specific DNA binding
KM415_RS15420	COG0346	lactoylglutathione lyase activity
KM415_RS15440	COG2169	Transcriptional regulator
KM415_RS15445	COG2169	Transcriptional regulator
KM415_RS15490	COG2814	Major facilitator Superfamily
KM415_RS15515	COG0745	RESPONSE REGULATOR receiver
KM415_RS15520	COG5002	protein histidine kinase activity
KM415_RS15520	COG3850	Histidine kinase
KM415_RS15545	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM415_RS15565	COG1476	TRANSCRIPTIONal
KM415_RS15580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS15585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM415_RS15595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM415_RS15600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM415_RS15615	COG1136	(ABC) transporter
KM415_RS15620	COG0577	efflux transmembrane transporter activity
KM415_RS15635	COG5002	protein histidine kinase activity
KM415_RS15635	COG3850	Histidine kinase
KM415_RS15645	COG2364	Membrane
KM415_RS15650	COG1846	Transcriptional regulator
KM415_RS15660	COG2808	Putative FMN-binding domain
KM415_RS15665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS15670	COG2271	Major facilitator Superfamily
KM415_RS15675	COG1556	Lactate utilization protein
KM415_RS15680	COG1139	Iron-sulfur cluster binding protein
KM415_RS15690	COG0583	DNA-binding transcription factor activity
KM415_RS15700	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM415_RS15720	COG0738	Major facilitator superfamily
KM415_RS15725	COG0673	inositol 2-dehydrogenase activity
KM415_RS15730	COG0561	phosphatase activity
KM415_RS15740	COG1609	Transcriptional regulator
KM415_RS15745	COG0457	Tetratricopeptide repeat
KM415_RS15765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM415_RS15795	COG0534	Mate efflux family protein
KM415_RS15815	COG2814	Major facilitator Superfamily
KM415_RS15820	COG1309	transcriptional regulator
KM415_RS15835	COG0814	amino acid
KM415_RS15840	COG1760	l-serine dehydratase
KM415_RS15845	COG1760	l-serine dehydratase
KM415_RS15855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM415_RS15860	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM415_RS15870	COG1335	isochorismatase
KM415_RS15875	COG1522	sequence-specific DNA binding
KM415_RS15880	COG0531	amino acid
KM415_RS15900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM415_RS15920	COG1595	DNA-templated transcription, initiation
KM415_RS15935	COG0662	Cupin 2, conserved barrel domain protein
KM415_RS15940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM415_RS15940	COG2207	Transcriptional regulator
KM415_RS15990	COG0477	Major facilitator Superfamily
KM415_RS16000	COG1846	Transcriptional regulator
KM415_RS16005	COG2814	Major facilitator Superfamily
KM415_RS16015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM415_RS16020	COG1131	(ABC) transporter
KM415_RS16040	COG2076	Multidrug Resistance protein
KM415_RS16045	COG1309	transcriptional regulator
KM415_RS16055	COG2031	fatty acid transporter
KM415_RS16065	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM415_RS16095	COG1122	ATPase activity
KM415_RS16100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM415_RS16115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM415_RS16120	COG1288	antiporter activity
KM415_RS16125	COG2356	endonuclease I
KM415_RS16140	COG3620	sequence-specific DNA binding
KM415_RS16145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM415_RS16150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM415_RS16155	COG0124	histidyl-tRNA synthetase
KM415_RS16170	COG1733	regulation of RNA biosynthetic process
KM415_RS16175	COG0778	Nitroreductase
KM415_RS16195	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS16205	COG1131	(ABC) transporter
KM415_RS16230	COG1011	Hydrolase
KM415_RS16240	COG2365	Tyrosine phosphatase family
KM415_RS16265	COG0346	lactoylglutathione lyase activity
KM415_RS16270	COG1940	carbohydrate kinase activity
KM415_RS16275	COG0738	Major facilitator superfamily
KM415_RS16280	COG0110	maltose O-acetyltransferase activity
KM415_RS16290	COG0577	efflux transmembrane transporter activity
KM415_RS16290	COG1136	(ABC) transporter
KM415_RS16305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM415_RS16310	COG0628	permease
KM415_RS16330	COG2226	methyltransferase
KM415_RS16340	COG0477	Major facilitator Superfamily
KM415_RS16370	COG1253	flavin adenine dinucleotide binding
KM415_RS16375	COG0789	Transcriptional regulator
KM415_RS16380	COG0697	spore germination
KM415_RS16385	COG1357	PFAM Pentapeptide repeats (8 copies)
KM415_RS16390	COG3813	Protein conserved in bacteria
KM415_RS16395	COG2706	6-phosphogluconolactonase activity
KM415_RS16400	COG1070	Carbohydrate kinase
KM415_RS16410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM415_RS16415	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM415_RS16425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM415_RS16430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM415_RS16435	COG0604	alcohol dehydrogenase
KM415_RS16440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM415_RS16450	COG3321	synthase
KM415_RS16450	COG0604	alcohol dehydrogenase
KM415_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS16480	COG0656	L-ascorbic acid biosynthetic process
KM415_RS16485	COG2814	Major facilitator Superfamily
KM415_RS16500	COG0346	lactoylglutathione lyase activity
KM415_RS16505	COG0814	amino acid
KM415_RS16530	COG1393	Belongs to the ArsC family
KM415_RS16535	COG1733	regulation of RNA biosynthetic process
KM415_RS16540	COG2188	Transcriptional regulator
KM415_RS16550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM415_RS16555	COG1733	regulation of RNA biosynthetic process
KM415_RS16560	COG1733	regulation of RNA biosynthetic process
KM415_RS16575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS16595	COG0384	phenazine biosynthesis protein PhzF
KM415_RS16605	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS16615	COG0318	PFAM AMP-dependent synthetase and ligase
KM415_RS16625	COG1733	regulation of RNA biosynthetic process
KM415_RS16655	COG1191	sigma factor activity
KM415_RS16670	COG1309	transcriptional regulator
KM415_RS16690	COG3152	Membrane
KM415_RS16715	COG1151	hydroxylamine reductase activity
KM415_RS16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS16730	COG3757	hydrolase, family 25
KM415_RS16730	COG3409	Peptidoglycan-binding domain 1 protein
KM415_RS16765	COG2072	flavoprotein involved in K transport
KM415_RS16800	COG0604	alcohol dehydrogenase
KM415_RS16805	COG1113	amino acid transport
KM415_RS16810	COG2814	Major facilitator Superfamily
KM415_RS16840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM415_RS16845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM415_RS16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS16880	COG3739	integral membrane protein
KM415_RS16885	COG0384	phenazine biosynthesis protein PhzF
KM415_RS16915	COG0583	DNA-binding transcription factor activity
KM415_RS16935	COG1193	negative regulation of DNA recombination
KM415_RS16960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM415_RS16990	COG0584	glycerophosphoryl diester phosphodiesterase
KM415_RS17015	COG0640	Transcriptional regulator
KM415_RS17020	COG0604	alcohol dehydrogenase
KM415_RS17040	COG2808	Putative FMN-binding domain
KM415_RS17045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM415_RS17055	COG0385	Bile acid
KM415_RS17060	COG0277	FAD linked oxidase domain protein
KM415_RS17090	COG1216	Glycosyl transferase, family 2
KM415_RS17095	COG1024	Enoyl-CoA hydratase
KM415_RS17105	COG1285	pathogenesis
KM415_RS17120	COG2514	catechol 2,3-dioxygenase activity
KM415_RS17125	COG2720	vancomycin resistance protein
KM415_RS17165	COG0716	FMN binding
KM415_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS17205	COG0165	Argininosuccinate lyase
KM415_RS17220	COG4145	pantothenate transmembrane transporter activity
KM415_RS17230	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS17235	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS17245	COG1657	PFAM Prenyltransferase squalene oxidase
KM415_RS17250	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM415_RS17255	COG2962	Rard protein
KM415_RS17260	COG3326	Membrane
KM415_RS17275	COG0489	protein tyrosine kinase activity
KM415_RS17285	COG0314	molybdopterin synthase activity
KM415_RS17290	COG0303	'Molybdopterin
KM415_RS17295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM415_RS17300	COG2116	formate transmembrane transporter activity
KM415_RS17310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM415_RS17315	COG5609	conserved protein (DUF2294)
KM415_RS17320	COG2427	Protein of unknown function (DUF1641)
KM415_RS17325	COG3383	formate dehydrogenase (NAD+) activity
KM415_RS17335	COG0697	spore germination
KM415_RS17375	COG2226	methyltransferase
KM415_RS17380	COG4166	transmembrane transport
KM415_RS17385	COG4166	transmembrane transport
KM415_RS17390	COG4166	transmembrane transport
KM415_RS17395	COG1301	dicarboxylic acid transport
KM415_RS17400	COG1316	TRANSCRIPTIONal
KM415_RS17410	COG1595	DNA-templated transcription, initiation
KM415_RS17430	COG1131	(ABC) transporter
KM415_RS17440	COG0673	inositol 2-dehydrogenase activity
KM415_RS17445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM415_RS17450	COG0187	DNA topoisomerase II activity
KM415_RS17455	COG1832	CoA-binding protein
KM415_RS17460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM415_RS17465	COG0745	RESPONSE REGULATOR receiver
KM415_RS17480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM415_RS17485	COG4841	protein insertion into membrane
KM415_RS17490	COG0824	Thioesterase
KM415_RS17520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM415_RS17530	COG2274	protein secretion by the type I secretion system
KM415_RS17535	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM415_RS17575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM415_RS17590	COG0183	Belongs to the thiolase family
KM415_RS17595	COG0318	PFAM AMP-dependent synthetase and ligase
KM415_RS17600	COG1268	BioY protein
KM415_RS17605	COG0318	PFAM AMP-dependent synthetase and ligase
KM415_RS17655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS17665	COG5002	protein histidine kinase activity
KM415_RS17670	COG0400	carboxylic ester hydrolase activity
KM415_RS17675	COG0346	lactoylglutathione lyase activity
KM415_RS17680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM415_RS17685	COG0069	glutamate synthase activity
KM415_RS17690	COG1902	pentaerythritol trinitrate reductase activity
KM415_RS17695	COG1329	Transcriptional regulator
KM415_RS17700	COG0010	Belongs to the arginase family
KM415_RS17725	COG2226	methyltransferase
KM415_RS17760	COG4846	Membrane protein involved in cytochrome C biogenesis
KM415_RS17765	COG0785	Cytochrome C biogenesis protein
KM415_RS17775	COG0583	DNA-binding transcription factor activity
KM415_RS17780	COG1380	Effector of murein hydrolase LrgA
KM415_RS17785	COG1346	cytolysis
KM415_RS17810	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM415_RS17810	COG3409	Peptidoglycan-binding domain 1 protein
KM415_RS17825	COG1132	(ABC) transporter
KM415_RS17830	COG1132	(ABC) transporter
KM415_RS17860	COG3639	organic phosphonate transmembrane transporter activity
KM415_RS17865	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM415_RS17885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM415_RS17905	COG1695	Transcriptional regulator
KM415_RS17945	COG1388	LysM domain
KM415_RS17945	COG3409	Peptidoglycan-binding domain 1 protein
KM415_RS17945	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM415_RS17950	COG4824	toxin secretion phage lysis holin
KM415_RS18105	COG1595	DNA-templated transcription, initiation
KM415_RS18150	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM415_RS18230	COG1396	sequence-specific DNA binding
KM415_RS18255	COG0174	glutamine synthetase
KM415_RS18260	COG0789	Transcriptional regulator
KM415_RS18265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM415_RS18275	COG2860	membrane
KM415_RS18280	COG0464	growth
KM415_RS18310	COG3584	3D domain protein
KM415_RS18310	COG1388	LysM domain
KM415_RS18315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM415_RS18315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM415_RS18315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM415_RS18320	COG1105	Belongs to the carbohydrate kinase PfkB family
KM415_RS18325	COG1349	DNA-binding transcription factor activity
KM415_RS18335	COG2322	membrane
KM415_RS18345	COG1113	amino acid transport
KM415_RS18360	COG1408	metallophosphoesterase
KM415_RS18365	COG2116	formate transmembrane transporter activity
KM415_RS18375	COG2217	Heavy metal translocating P-type atpase
KM415_RS18380	COG2608	mercury ion transmembrane transporter activity
KM415_RS18385	COG1937	Protein conserved in bacteria
KM415_RS18395	COG2819	hydrolase of the alpha beta superfamily
KM415_RS18400	COG1120	ATPase activity
KM415_RS18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS18410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS18420	COG0708	Exodeoxyribonuclease III
KM415_RS18425	COG2169	Transcriptional regulator
KM415_RS18430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM415_RS18435	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM415_RS18445	COG2364	Membrane
KM415_RS18460	COG2267	carboxylic ester hydrolase activity
KM415_RS18465	COG0346	lactoylglutathione lyase activity
KM415_RS18470	COG3300	MHYT domain
KM415_RS18470	COG5001	Diguanylate cyclase
KM415_RS18490	COG1346	cytolysis
KM415_RS18495	COG1380	Effector of murein hydrolase LrgA
KM415_RS18500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM415_RS18505	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM415_RS18505	COG0596	Alpha beta hydrolase
KM415_RS18510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM415_RS18530	COG1404	Belongs to the peptidase S8 family
KM415_RS18535	COG3773	Cell wall hydrolase
KM415_RS18540	COG0562	UDP-galactopyranose mutase
KM415_RS18545	COG1368	sulfuric ester hydrolase activity
KM415_RS18550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM415_RS18560	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM415_RS18585	COG1131	(ABC) transporter
KM415_RS18605	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM415_RS18610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM415_RS18615	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM415_RS18620	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM415_RS18620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM415_RS18630	COG2359	stage V sporulation protein S
KM415_RS18635	COG1692	metallophosphoesterase
KM415_RS18660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM415_RS18665	COG1426	Protein conserved in bacteria
KM415_RS18680	COG0300	oxidoreductase activity
KM415_RS18685	COG0612	Peptidase, M16
KM415_RS18690	COG0612	Peptidase, M16
KM415_RS18695	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM415_RS18705	COG3845	ABC transporter
KM415_RS18710	COG1744	ABC transporter substrate-binding protein PnrA-like
KM415_RS18715	COG2188	Transcriptional regulator
KM415_RS18720	COG1674	ftsk spoiiie
KM415_RS18730	COG0740	serine-type endopeptidase activity
KM415_RS18735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM415_RS18745	COG0527	aspartate kinase activity
KM415_RS18750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM415_RS18755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM415_RS18760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM415_RS18765	COG1873	PFAM PRC-barrel domain
KM415_RS18770	COG0612	Peptidase, M16
KM415_RS18775	COG0726	polysaccharide deacetylase
KM415_RS18790	COG0196	riboflavin kinase activity
KM415_RS18795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM415_RS18805	COG1550	Protein conserved in bacteria
KM415_RS18815	COG1358	cellular component organization or biogenesis
KM415_RS18820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM415_RS18825	COG0195	Participates in both transcription termination and antitermination
KM415_RS18845	COG0750	zinc metalloprotease
KM415_RS18855	COG4589	Belongs to the CDS family
KM415_RS18860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM415_RS18870	COG0528	UMP kinase activity
KM415_RS18900	COG4974	Belongs to the 'phage' integrase family
KM415_RS18910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM415_RS18920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM415_RS18960	COG1837	Belongs to the UPF0109 family
KM415_RS18970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM415_RS18980	COG0552	protein localization to endoplasmic reticulum
KM415_RS18985	COG1196	nuclear chromosome segregation
KM415_RS18995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM415_RS19000	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS19005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM415_RS19020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM415_RS19025	COG1461	Dihydroxyacetone kinase
KM415_RS19030	COG1302	Protein conserved in bacteria
KM415_RS19045	COG1564	THIamine pyrophosphokinase
KM415_RS19050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM415_RS19055	COG1162	GTPase activity
KM415_RS19060	COG0515	serine threonine protein kinase
KM415_RS19060	COG2815	serine threonine protein kinase
KM415_RS19065	COG0631	protein serine/threonine phosphatase activity
KM415_RS19075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM415_RS19075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM415_RS19085	COG0242	peptide deformylase activity
KM415_RS19090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM415_RS19095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM415_RS19115	COG1561	YicC-like family, N-terminal region
KM415_RS19120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM415_RS19130	COG0006	proline dipeptidase activity
KM415_RS19145	COG3069	C4-dicarboxylate transmembrane transporter activity
KM415_RS19210	COG0564	pseudouridine synthase activity
KM415_RS19230	COG3599	regulation of cell shape
KM415_RS19235	COG2302	S4 RNA-binding domain
KM415_RS19240	COG0762	integral membrane protein
KM415_RS19250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM415_RS19255	COG1496	oxidoreductase activity
KM415_RS19260	COG1873	PFAM PRC-barrel domain
KM415_RS19265	COG1191	sigma factor activity
KM415_RS19270	COG1191	sigma factor activity
KM415_RS19280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM415_RS19285	COG0849	cell division
KM415_RS19290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM415_RS19295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM415_RS19305	COG0772	Belongs to the SEDS family
KM415_RS19320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM415_RS19325	COG0768	penicillin binding
KM415_RS19330	COG0768	penicillin binding
KM415_RS19335	COG4839	cell division protein FtsL
KM415_RS19350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM415_RS19365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM415_RS19370	COG1399	metal-binding, possibly nucleic acid-binding protein
KM415_RS19415	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM415_RS19415	COG3409	Peptidoglycan-binding domain 1 protein
KM415_RS19420	COG4824	toxin secretion phage lysis holin
KM415_RS19515	COG1802	Transcriptional regulator
KM415_RS19515	COG4626	Terminase
KM415_RS19540	COG0582	viral genome integration into host DNA
KM415_RS19605	COG0756	dUTP diphosphatase activity
KM415_RS19620	COG1191	sigma factor activity
KM415_RS19645	COG1484	DNA-dependent DNA replication
KM415_RS19675	COG1396	sequence-specific DNA binding
KM415_RS19690	COG1396	sequence-specific DNA binding
KM415_RS19705	COG0582	viral genome integration into host DNA
KM415_RS19715	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM415_RS19720	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM415_RS19725	COG3314	Sporulation integral membrane protein YlbJ
KM415_RS19735	COG0742	ribosomal rna small subunit methyltransferase
KM415_RS19750	COG3679	Belongs to the UPF0342 family
KM415_RS19755	COG0406	alpha-ribazole phosphatase activity
KM415_RS19770	COG2340	Cysteine-rich secretory protein family
KM415_RS19785	COG3336	cytochrome c oxidase
KM415_RS19820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM415_RS19825	COG0772	Belongs to the SEDS family
KM415_RS19835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM415_RS19840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM415_RS19850	COG4896	Protein conserved in bacteria
KM415_RS19865	COG1217	gtp-binding protein TYPA
KM415_RS19875	COG0483	inositol monophosphate 1-phosphatase activity
KM415_RS19895	COG1982	Orn Lys Arg decarboxylase major
KM415_RS19940	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM415_RS19945	COG0022	dehydrogenase e1 component
KM415_RS19950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM415_RS19960	COG0242	peptide deformylase activity
KM415_RS19965	COG0561	phosphatase activity
KM415_RS19975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM415_RS19980	COG0569	domain protein
KM415_RS20000	COG0583	DNA-binding transcription factor activity
KM415_RS20005	COG0517	IMP dehydrogenase activity
KM415_RS20015	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM415_RS20025	COG4703	Protein of unknown function (DUF1797)
KM415_RS20040	COG2200	EAL domain
KM415_RS20045	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS20050	COG1408	metallophosphoesterase
KM415_RS20060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM415_RS20095	COG2814	Major facilitator Superfamily
KM415_RS20115	COG3209	COG3209 Rhs family protein
KM415_RS20125	COG2205	protein histidine kinase activity
KM415_RS20135	COG0436	Aminotransferase
KM415_RS20140	COG1609	Transcriptional regulator
KM415_RS20145	COG3833	ABC-type maltose transport systems, permease component
KM415_RS20150	COG1175	transmembrane transport
KM415_RS20155	COG2182	Extracellular solute-binding protein
KM415_RS20165	COG0366	Alpha amylase catalytic
KM415_RS20170	COG3842	ATPase activity
KM415_RS20210	COG0183	Belongs to the thiolase family
KM415_RS20245	COG1695	Transcriptional regulator
KM415_RS20250	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS20260	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM415_RS20270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM415_RS20275	COG0436	Aminotransferase
KM415_RS20295	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM415_RS20315	COG2199	diguanylate cyclase activity
KM415_RS20320	COG0778	Nitroreductase
KM415_RS20345	COG1263	PTS System
KM415_RS20345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM415_RS20345	COG2190	(PTS) system
KM415_RS20350	COG3711	transcriptional antiterminator
KM415_RS20360	COG2188	Transcriptional regulator
KM415_RS20370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM415_RS20395	COG1547	Domain of unknown function (DUF309)
KM415_RS20400	COG0456	acetyltransferase
KM415_RS20410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM415_RS20415	COG4086	secreted protein
KM415_RS20420	COG0561	phosphatase activity
KM415_RS20425	COG0697	spore germination
KM415_RS20440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM415_RS20465	COG0733	neurotransmitter:sodium symporter activity
KM415_RS20485	COG1686	Belongs to the peptidase S11 family
KM415_RS20490	COG1725	Transcriptional regulator
KM415_RS20495	COG1131	(ABC) transporter
KM415_RS20510	COG1846	Transcriptional regulator
KM415_RS20525	COG0598	Magnesium transport protein CorA
KM415_RS20550	COG4974	Belongs to the 'phage' integrase family
KM415_RS20560	COG0735	belongs to the Fur family
KM415_RS20565	COG1300	Membrane
KM415_RS20585	COG0667	Aldo Keto reductase
KM415_RS20590	COG0656	L-ascorbic acid biosynthetic process
KM415_RS20595	COG0456	acetyltransferase
KM415_RS20595	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM415_RS20605	COG0737	Belongs to the 5'-nucleotidase family
KM415_RS20605	COG1525	nuclease
KM415_RS20605	COG4085	toxin activity
KM415_RS20615	COG0596	Alpha beta hydrolase
KM415_RS20620	COG2056	Na+-H+ antiporter family
KM415_RS20625	COG1609	Transcriptional regulator
KM415_RS20630	COG0456	acetyltransferase
KM415_RS20635	COG1073	alpha beta
KM415_RS20650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM415_RS20650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM415_RS20655	COG0307	riboflavin synthase, alpha
KM415_RS20680	COG4106	trans-aconitate 2-methyltransferase activity
KM415_RS20685	COG1073	alpha beta
KM415_RS20685	COG2226	methyltransferase
KM415_RS20700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM415_RS20710	COG1757	Na H antiporter
KM415_RS20715	COG0737	Belongs to the 5'-nucleotidase family
KM415_RS20725	COG1522	sequence-specific DNA binding
KM415_RS20745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM415_RS20755	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM415_RS20770	COG0300	oxidoreductase activity
KM415_RS20780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM415_RS20785	COG1760	l-serine dehydratase
KM415_RS20790	COG1760	l-serine dehydratase
KM415_RS20810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM415_RS20820	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM415_RS20825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS20840	COG1376	ErfK ybiS ycfS ynhG family protein
KM415_RS20845	COG4129	membrane
KM415_RS20850	COG1126	abc transporter atp-binding protein
KM415_RS20855	COG0765	amino acid transport
KM415_RS20860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM415_RS20875	COG2816	NAD+ diphosphatase activity
KM415_RS20880	COG0772	Belongs to the SEDS family
KM415_RS20885	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM415_RS20890	COG0022	dehydrogenase e1 component
KM415_RS20895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM415_RS20900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM415_RS20915	COG0280	phosphate acetyltransferase
KM415_RS20920	COG3829	transcription factor binding
KM415_RS20920	COG3290	protein histidine kinase activity
KM415_RS20930	COG0584	glycerophosphoryl diester phosphodiesterase
KM415_RS20935	COG3093	addiction module antidote protein HigA
KM415_RS20945	COG0745	RESPONSE REGULATOR receiver
KM415_RS20950	COG0750	zinc metalloprotease
KM415_RS20955	COG0497	DNA recombination
KM415_RS20965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM415_RS20975	COG0142	geranyltranstransferase activity
KM415_RS21000	COG1302	Protein conserved in bacteria
KM415_RS21005	COG0439	Biotin carboxylase
KM415_RS21010	COG0511	ligase activity, forming carbon-carbon bonds
KM415_RS21055	COG3854	ATPases associated with a variety of cellular activities
KM415_RS21080	COG0006	proline dipeptidase activity
KM415_RS21095	COG3872	metal-dependent enzyme
KM415_RS21105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM415_RS21125	COG0095	Lipoate-protein ligase
KM415_RS21130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM415_RS21135	COG1609	Transcriptional regulator
KM415_RS21145	COG2076	Multidrug Resistance protein
KM415_RS21150	COG2076	Multidrug Resistance protein
KM415_RS21185	COG1131	(ABC) transporter
KM415_RS21190	COG1725	Transcriptional regulator
KM415_RS21220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM415_RS21275	COG4970	Tfp pilus assembly protein FimT
KM415_RS21285	COG1459	type II secretion system
KM415_RS21290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM415_RS21340	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM415_RS21345	COG0646	methionine synthase
KM415_RS21345	COG1410	methionine synthase
KM415_RS21350	COG0646	methionine synthase
KM415_RS21350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM415_RS21355	COG0626	cystathionine gamma-synthase activity
KM415_RS21360	COG0626	cystathionine gamma-synthase activity
KM415_RS21380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS21390	COG1940	carbohydrate kinase activity
KM415_RS21395	COG4483	Protein conserved in bacteria
KM415_RS21400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM415_RS21405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM415_RS21410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM415_RS21415	COG0704	Plays a role in the regulation of phosphate uptake
KM415_RS21425	COG0581	inorganic phosphate transmembrane transporter activity
KM415_RS21430	COG0573	inorganic phosphate transmembrane transporter activity
KM415_RS21435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM415_RS21440	COG0768	penicillin binding
KM415_RS21445	COG0477	Major facilitator Superfamily
KM415_RS21450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM415_RS21475	COG0735	belongs to the Fur family
KM415_RS21480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM415_RS21485	COG1121	(ABC) transporter
KM415_RS21490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS21520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM415_RS21525	COG2384	SAM-dependent methyltransferase
KM415_RS21530	COG2010	Cytochrome c
KM415_RS21535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM415_RS21540	COG0358	DNA primase activity
KM415_RS21550	COG0517	IMP dehydrogenase activity
KM415_RS21565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM415_RS21570	COG0295	cytidine deaminase activity
KM415_RS21575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM415_RS21585	COG1480	7TM receptor with intracellular HD hydrolase
KM415_RS21590	COG1702	phosphate starvation-inducible protein PhoH
KM415_RS21605	COG1610	YqeY-like protein
KM415_RS21610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM415_RS21615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM415_RS21620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM415_RS21650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM415_RS21655	COG1733	regulation of RNA biosynthetic process
KM415_RS21680	COG1466	dna polymerase III delta subunit
KM415_RS21690	COG0658	competence protein
KM415_RS21690	COG2333	competence protein COMEC
KM415_RS21695	COG2131	deaminase
KM415_RS21700	COG1555	photosystem II stabilization
KM415_RS21700	COG1596	polysaccharide export
KM415_RS21705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM415_RS21710	COG2226	methyltransferase
KM415_RS21715	COG0799	negative regulation of ribosome biogenesis
KM415_RS21720	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM415_RS21730	COG1534	Rna-binding protein
KM415_RS21740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM415_RS21745	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM415_RS21770	COG1595	DNA-templated transcription, initiation
KM415_RS21780	COG0778	Nitroreductase
KM415_RS21785	COG2357	RelA SpoT domain protein
KM415_RS21795	COG1785	Belongs to the alkaline phosphatase family
KM415_RS21805	COG2267	carboxylic ester hydrolase activity
KM415_RS21840	COG1404	Belongs to the peptidase S8 family
KM415_RS21845	COG3186	Phenylalanine-4-hydroxylase
KM415_RS21860	COG2259	Doxx family
KM415_RS21900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM415_RS21910	COG1012	belongs to the aldehyde dehydrogenase family
KM415_RS21910	COG1454	alcohol dehydrogenase
KM415_RS21915	COG0626	cystathionine gamma-synthase activity
KM415_RS21920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM415_RS21945	COG0768	penicillin binding
KM415_RS21960	COG0826	peptidase U32
KM415_RS21965	COG0826	peptidase U32
KM415_RS21970	COG4122	O-methyltransferase activity
KM415_RS21975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM415_RS21995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM415_RS22005	COG0628	permease
KM415_RS22025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM415_RS22035	COG0482	sulfurtransferase activity
KM415_RS22040	COG1104	cysteine desulfurase activity
KM415_RS22045	COG1959	2 iron, 2 sulfur cluster binding
KM415_RS22050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM415_RS22060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM415_RS22085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM415_RS22095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM415_RS22095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM415_RS22100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM415_RS22105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM415_RS22105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM415_RS22115	COG2244	polysaccharide biosynthetic process
KM415_RS22120	COG2323	membrane
KM415_RS22130	COG1862	Preprotein translocase
KM415_RS22160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM415_RS22170	COG0697	spore germination
KM415_RS22175	COG0697	spore germination
KM415_RS22180	COG0640	Transcriptional regulator
KM415_RS22205	COG0157	Belongs to the NadC ModD family
KM415_RS22210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM415_RS22215	COG1104	cysteine desulfurase activity
KM415_RS22220	COG1827	regulation of RNA biosynthetic process
KM415_RS22225	COG2258	MOSC domain
KM415_RS22230	COG0077	Prephenate dehydratase
KM415_RS22235	COG0577	efflux transmembrane transporter activity
KM415_RS22240	COG0577	efflux transmembrane transporter activity
KM415_RS22245	COG1136	(ABC) transporter
KM415_RS22255	COG0745	RESPONSE REGULATOR receiver
KM415_RS22260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM415_RS22265	COG3290	protein histidine kinase activity
KM415_RS22275	COG2868	ribosomal protein
KM415_RS22285	COG1530	ribonuclease E activity
KM415_RS22290	COG1994	Peptidase M50
KM415_RS22295	COG0739	heme binding
KM415_RS22300	COG2894	cell division
KM415_RS22320	COG1077	Cell shape determining protein MreB Mrl
KM415_RS22340	COG0285	dihydrofolate synthase activity
KM415_RS22345	COG0525	valine-tRNA ligase activity
KM415_RS22355	COG1388	LysM domain
KM415_RS22365	COG0113	porphobilinogen synthase activity
KM415_RS22370	COG1587	Uroporphyrinogen-III synthase
KM415_RS22380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM415_RS22390	COG1846	Transcriptional regulator
KM415_RS22395	COG1764	response to oxidative stress
KM415_RS22410	COG0470	DNA polymerase III
KM415_RS22410	COG1067	ATP-dependent peptidase activity
KM415_RS22455	COG0622	Phosphoesterase
KM415_RS22470	COG5401	PFAM Sporulation and spore germination
KM415_RS22490	COG1309	transcriptional regulator
KM415_RS22505	COG2197	response regulator
KM415_RS22510	COG2233	PERMEase
KM415_RS22520	COG0402	S-adenosylhomocysteine deaminase activity
KM415_RS22525	COG0402	S-adenosylhomocysteine deaminase activity
KM415_RS22535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM415_RS22545	COG0444	Belongs to the ABC transporter superfamily
KM415_RS22550	COG4608	Belongs to the ABC transporter superfamily
KM415_RS22555	COG3275	phosphorelay sensor kinase activity
KM415_RS22560	COG3279	Response regulator of the LytR AlgR family
KM415_RS22575	COG1983	PspC domain protein
KM415_RS22580	COG1396	sequence-specific DNA binding
KM415_RS22585	COG0697	spore germination
KM415_RS22595	COG1959	2 iron, 2 sulfur cluster binding
KM415_RS22600	COG1668	transmembrane transport
KM415_RS22605	COG4152	abc transporter atp-binding protein
KM415_RS22610	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM415_RS22620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM415_RS22625	COG1876	peptidase activity
KM415_RS22630	COG0824	Thioesterase
KM415_RS22635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM415_RS22640	COG1053	succinate dehydrogenase
KM415_RS22645	COG2009	succinate dehydrogenase
KM415_RS22650	COG1719	4-vinyl reductase, 4VR
KM415_RS22660	COG3118	belongs to the thioredoxin family
KM415_RS22665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM415_RS22670	COG2086	electron transfer activity
KM415_RS22675	COG1024	Enoyl-CoA hydratase
KM415_RS22685	COG0318	PFAM AMP-dependent synthetase and ligase
KM415_RS22705	COG2318	DinB family
KM415_RS22735	COG1131	(ABC) transporter
KM415_RS22740	COG2205	protein histidine kinase activity
KM415_RS22745	COG0745	RESPONSE REGULATOR receiver
KM415_RS22755	COG4895	conserved protein (DUF2196)
KM415_RS22760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM415_RS22775	COG4509	Sortase family
KM415_RS22780	COG1120	ATPase activity
KM415_RS22795	COG5386	Cell surface protein
KM415_RS22805	COG5386	Cell surface protein
KM415_RS22810	COG1114	Component of the transport system for branched-chain amino acids
KM415_RS22815	COG1187	pseudouridine synthase activity
KM415_RS22825	COG1796	DNA polymerase
KM415_RS22825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM415_RS22830	COG1286	toxin biosynthetic process
KM415_RS22875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM415_RS22885	COG1418	mRNA catabolic process
KM415_RS22910	COG2814	Major facilitator Superfamily
KM415_RS22915	COG1566	PFAM secretion protein HlyD family protein
KM415_RS22920	COG1309	transcriptional regulator
KM415_RS22925	COG1363	Peptidase, m42
KM415_RS22950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM415_RS22960	COG1484	DNA-dependent DNA replication
KM415_RS22965	COG3611	Membrane attachment protein
KM415_RS22975	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM415_RS22980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM415_RS22985	COG0237	dephospho-CoA kinase activity
KM415_RS22990	COG1971	Probably functions as a manganese efflux pump
KM415_RS23000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM415_RS23000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM415_RS23005	COG5002	protein histidine kinase activity
KM415_RS23010	COG0745	RESPONSE REGULATOR receiver
KM415_RS23030	COG0538	isocitrate dehydrogenase activity
KM415_RS23035	COG0372	Belongs to the citrate synthase family
KM415_RS23045	COG0628	permease
KM415_RS23050	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM415_RS23075	COG1725	Transcriptional regulator
KM415_RS23080	COG0281	malic enzyme
KM415_RS23085	COG0587	DNA-directed DNA polymerase activity
KM415_RS23100	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM415_RS23120	COG4109	DRTGG domain
KM415_RS23135	COG0006	proline dipeptidase activity
KM415_RS23175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS23180	COG0662	Cupin 2, conserved barrel domain protein
KM415_RS23190	COG1476	TRANSCRIPTIONal
KM415_RS23205	COG1028	Short-chain dehydrogenase reductase Sdr
KM415_RS23210	COG0589	response to stress
KM415_RS23250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS23270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM415_RS23275	COG0827	DNA restriction-modification system
KM415_RS23280	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM415_RS23285	COG3874	Sporulation protein YtfJ
KM415_RS23300	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM415_RS23310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM415_RS23325	COG1104	cysteine desulfurase activity
KM415_RS23335	COG0583	DNA-binding transcription factor activity
KM415_RS23340	COG0697	spore germination
KM415_RS23350	COG1956	GAF domain-containing protein
KM415_RS23355	COG0626	cystathionine gamma-synthase activity
KM415_RS23385	COG1595	DNA-templated transcription, initiation
KM415_RS23395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM415_RS23400	COG0454	-acetyltransferase
KM415_RS23405	COG0517	IMP dehydrogenase activity
KM415_RS23410	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM415_RS23420	COG0745	RESPONSE REGULATOR receiver
KM415_RS23430	COG0666	response to abiotic stimulus
KM415_RS23465	COG1609	Transcriptional regulator
KM415_RS23470	COG4851	CamS sex pheromone cAM373 precursor
KM415_RS23475	COG3118	belongs to the thioredoxin family
KM415_RS23485	COG2309	aminopeptidase activity
KM415_RS23505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS23520	COG1674	ftsk spoiiie
KM415_RS23530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM415_RS23535	COG4848	Belongs to the UPF0354 family
KM415_RS23540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM415_RS23545	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM415_RS23550	COG1363	Peptidase, m42
KM415_RS23560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS23575	COG0510	thiamine kinase activity
KM415_RS23580	COG1523	belongs to the glycosyl hydrolase 13 family
KM415_RS23595	COG1349	DNA-binding transcription factor activity
KM415_RS23600	COG1187	pseudouridine synthase activity
KM415_RS23605	COG2244	polysaccharide biosynthetic process
KM415_RS23610	COG2081	HI0933 family
KM415_RS23615	COG2814	Major facilitator Superfamily
KM415_RS23625	COG3832	glyoxalase III activity
KM415_RS23645	COG1329	Transcriptional regulator
KM415_RS23655	COG4975	Glucose uptake
KM415_RS23670	COG0314	molybdopterin synthase activity
KM415_RS23675	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM415_RS23680	COG0303	'Molybdopterin
KM415_RS23690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM415_RS23715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM415_RS23725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM415_RS23765	COG2814	Major facilitator Superfamily
KM415_RS23770	COG0475	glutathione-regulated potassium exporter activity
KM415_RS23775	COG0490	domain, Protein
KM415_RS23780	COG0582	viral genome integration into host DNA
KM415_RS23790	COG1136	(ABC) transporter
KM415_RS23810	COG1242	4 iron, 4 sulfur cluster binding
KM415_RS23815	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM415_RS23820	COG1131	(ABC) transporter
KM415_RS23830	COG1794	racemase activity, acting on amino acids and derivatives
KM415_RS23850	COG2267	carboxylic ester hydrolase activity
KM415_RS23855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM415_RS23860	COG0671	phosphoesterase, PA-phosphatase related
KM415_RS23865	COG0438	transferase activity, transferring glycosyl groups
KM415_RS23875	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM415_RS23930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM415_RS23935	COG5002	protein histidine kinase activity
KM415_RS23940	COG4191	Histidine kinase
KM415_RS23945	COG2267	carboxylic ester hydrolase activity
KM415_RS23965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM415_RS23970	COG1116	anion transmembrane transporter activity
KM415_RS23975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM415_RS24000	COG0494	nUDIX hydrolase
KM415_RS24035	COG0288	reversible hydration of carbon dioxide
KM415_RS24040	COG1271	oxidase subunit
KM415_RS24045	COG1294	oxidase, subunit
KM415_RS24065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS24090	COG1842	Phage shock protein A
KM415_RS24120	COG5002	protein histidine kinase activity
KM415_RS24125	COG0745	RESPONSE REGULATOR receiver
KM415_RS24155	COG1597	lipid kinase activity
KM415_RS24190	COG0586	Pfam SNARE associated Golgi protein
KM415_RS24200	COG0577	efflux transmembrane transporter activity
KM415_RS24205	COG1136	(ABC) transporter
KM415_RS24210	COG3708	Transcriptional regulator
KM415_RS24210	COG2207	Transcriptional regulator
KM415_RS24215	COG0745	RESPONSE REGULATOR receiver
KM415_RS24220	COG2205	protein histidine kinase activity
KM415_RS24230	COG0577	efflux transmembrane transporter activity
KM415_RS24235	COG1136	(ABC) transporter
KM415_RS24255	COG2188	Transcriptional regulator
KM415_RS24275	COG3964	amidohydrolase
KM415_RS24305	COG4948	Mandelate Racemase Muconate Lactonizing
KM415_RS24315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM415_RS24320	COG0596	Alpha beta hydrolase
KM415_RS24325	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM415_RS24330	COG1169	isochorismate synthase
KM415_RS24335	COG1575	Belongs to the MenA family. Type 1 subfamily
KM415_RS24340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM415_RS24360	COG0058	SHG alpha-glucan phosphorylase activity
KM415_RS24365	COG0297	glycogen (starch) synthase activity
KM415_RS24370	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM415_RS24485	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM415_RS24520	COG1285	pathogenesis
KM415_RS24525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM415_RS24535	COG0166	Belongs to the GPI family
KM415_RS24540	COG2155	Conserved Protein
KM415_RS24545	COG1098	S1 RNA binding domain
KM415_RS24550	COG0436	Aminotransferase
KM415_RS24555	COG1522	sequence-specific DNA binding
KM415_RS24560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM415_RS24565	COG2267	carboxylic ester hydrolase activity
KM415_RS24575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM415_RS24595	COG5018	Exonuclease
KM415_RS24600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM415_RS24620	COG2050	protein possibly involved in aromatic compounds catabolism
KM415_RS24630	COG1268	BioY protein
KM415_RS24640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM415_RS24645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM415_RS24660	COG3584	3D domain protein
KM415_RS24675	COG1252	NADH dehydrogenase
KM415_RS24690	COG3708	Transcriptional regulator
KM415_RS24705	COG1683	Conserved Protein
KM415_RS24725	COG0316	Belongs to the HesB IscA family
KM415_RS24740	COG1252	NADH dehydrogenase
KM415_RS24755	COG0390	transport system, permease component
KM415_RS24760	COG2824	Alkylphosphonate utilization operon protein PhnA
KM415_RS24800	COG4837	Protein of unknown function (DUF1462)
KM415_RS24805	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM415_RS24815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM415_RS24820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM415_RS24830	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM415_RS24835	COG0647	UMP catabolic process
KM415_RS24845	COG2445	Protein of unknown function DUF86
KM415_RS24850	COG1494	fructose-1,6-bisphosphatase
KM415_RS24865	COG4470	Protein conserved in bacteria
KM415_RS24875	COG0789	Transcriptional regulator
KM415_RS24880	COG4377	Putative membrane peptidase family (DUF2324)
KM415_RS24905	COG0739	heme binding
KM415_RS24915	COG3377	Domain of unknown function (DUF1805)
KM415_RS24920	COG0737	Belongs to the 5'-nucleotidase family
KM415_RS24925	COG1695	Transcriptional regulator
KM415_RS24935	COG0719	Fe-S assembly protein
KM415_RS24940	COG0822	iron-sulfur transferase activity
KM415_RS24945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM415_RS24950	COG0719	Fe-S assembly protein
KM415_RS24955	COG0396	ATPase activity
KM415_RS24960	COG1464	Belongs to the NlpA lipoprotein family
KM415_RS24965	COG1464	Belongs to the NlpA lipoprotein family
KM415_RS24970	COG2011	ABC-type metal ion transport system permease component
KM415_RS24975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM415_RS24985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM415_RS24990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM415_RS25000	COG1393	Belongs to the ArsC family
KM415_RS25045	COG0039	L-malate dehydrogenase activity
KM415_RS25070	COG1309	transcriptional regulator
KM415_RS25075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM415_RS25080	COG1960	acyl-CoA dehydrogenase activity
KM415_RS25085	COG0183	Belongs to the thiolase family
KM415_RS25090	COG1024	Enoyl-CoA hydratase
KM415_RS25090	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM415_RS25100	COG1686	Belongs to the peptidase S11 family
KM415_RS25115	COG0011	TIGRFAM Protein of
KM415_RS25120	COG0840	transmembrane signaling receptor activity
KM415_RS25140	COG2814	Major facilitator Superfamily
KM415_RS25145	COG0531	amino acid
KM415_RS25155	COG0706	membrane insertase activity
KM415_RS25165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM415_RS25200	COG0586	Pfam SNARE associated Golgi protein
KM415_RS25210	COG1376	ErfK ybiS ycfS ynhG family protein
KM415_RS25215	COG0745	RESPONSE REGULATOR receiver
KM415_RS25220	COG5002	protein histidine kinase activity
KM415_RS25245	COG2151	metal-sulfur cluster biosynthetic enzyme
KM415_RS25250	COG3227	Zinc metalloprotease (Elastase)
KM415_RS25255	COG1741	Belongs to the pirin family
KM415_RS25270	COG0475	glutathione-regulated potassium exporter activity
KM415_RS25275	COG0490	domain, Protein
KM415_RS25280	COG1115	amino acid carrier protein
KM415_RS25285	COG0783	Belongs to the Dps family
KM415_RS25300	COG1611	Belongs to the LOG family
KM415_RS25320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS25325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS25330	COG1115	amino acid carrier protein
KM415_RS25335	COG1115	amino acid carrier protein
KM415_RS25340	COG2910	NAD(P)H-binding
KM415_RS25355	COG0656	L-ascorbic acid biosynthetic process
KM415_RS25360	COG2814	Major facilitator Superfamily
KM415_RS25365	COG1733	regulation of RNA biosynthetic process
KM415_RS25375	COG1252	NADH dehydrogenase
KM415_RS25380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM415_RS25385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM415_RS25395	COG3290	protein histidine kinase activity
KM415_RS25395	COG0840	transmembrane signaling receptor activity
KM415_RS25405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM415_RS25410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM415_RS25425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM415_RS25480	COG0557	exoribonuclease II activity
KM415_RS25485	COG1647	Serine aminopeptidase, S33
KM415_RS25490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM415_RS25495	COG1346	cytolysis
KM415_RS25590	COG4695	Portal protein
KM415_RS25615	COG4974	Belongs to the 'phage' integrase family
KM415_RS25625	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM415_RS25630	COG0149	triose-phosphate isomerase activity
KM415_RS25640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM415_RS25655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM415_RS25680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM415_RS25695	COG2323	membrane
KM415_RS25700	COG0740	serine-type endopeptidase activity
KM415_RS25705	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM415_RS25715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM415_RS25725	COG1051	belongs to the nudix hydrolase family
KM415_RS25735	COG0492	ferredoxin-NADP+ reductase activity
KM415_RS25740	COG0457	Tetratricopeptide repeat
KM415_RS25745	COG0110	maltose O-acetyltransferase activity
KM415_RS25765	COG1950	PFAM Membrane protein of
KM415_RS25775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM415_RS25780	COG0556	nucleotide-excision repair
KM415_RS25800	COG0789	Transcriptional regulator
KM415_RS25825	COG2855	membrane
KM415_RS25830	COG0583	DNA-binding transcription factor activity
KM415_RS25840	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM415_RS25845	COG0488	(ABC) transporter
KM415_RS25855	COG1132	(ABC) transporter
KM415_RS25860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM415_RS25865	COG3409	Peptidoglycan-binding domain 1 protein
KM415_RS25865	COG0793	Belongs to the peptidase S41A family
KM415_RS25870	COG2177	Part of the ABC transporter FtsEX involved in
KM415_RS25875	COG2884	Cell division ATP-binding protein ftsE
KM415_RS25890	COG0653	protein targeting
KM415_RS25895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM415_RS25900	COG1278	Cold shock
KM415_RS25905	COG1040	competence protein
KM415_RS25910	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM415_RS25915	COG1388	LysM domain
KM415_RS25915	COG0791	NLP P60 protein
KM415_RS25920	COG1733	regulation of RNA biosynthetic process
KM415_RS25925	COG1307	EDD domain protein, DegV family
KM415_RS25930	COG1739	Uncharacterized protein family UPF0029
KM415_RS25935	COG1316	TRANSCRIPTIONal
KM415_RS25940	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM415_RS25945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM415_RS25950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM415_RS25960	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM415_RS25960	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM415_RS25975	COG3394	polysaccharide catabolic process
KM415_RS25980	COG1486	melibiose metabolic process
KM415_RS25985	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM415_RS25990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM415_RS26000	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM415_RS26005	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM415_RS26010	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM415_RS26020	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM415_RS26025	COG1301	dicarboxylic acid transport
KM415_RS26035	COG0346	lactoylglutathione lyase activity
KM415_RS26040	COG1511	domain protein
KM415_RS26045	COG0583	DNA-binding transcription factor activity
KM415_RS26050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM415_RS26065	COG1271	oxidase subunit
KM415_RS26070	COG1294	oxidase, subunit
KM415_RS26075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM415_RS26095	COG2389	metal-binding protein
KM415_RS26105	COG1368	sulfuric ester hydrolase activity
KM415_RS26120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM415_RS26130	COG1215	transferase activity, transferring glycosyl groups
KM415_RS26135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM415_RS26140	COG1388	LysM domain
KM415_RS26140	COG3584	3D domain protein
KM415_RS26165	COG4715	Zinc finger, swim domain protein
KM415_RS26170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM415_RS26210	COG0577	efflux transmembrane transporter activity
KM415_RS26215	COG1136	(ABC) transporter
KM415_RS26250	COG5002	protein histidine kinase activity
KM415_RS26255	COG0745	RESPONSE REGULATOR receiver
KM415_RS26260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM415_RS26280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM415_RS26285	COG1134	teichoic acid transport
KM415_RS26290	COG1682	transport, permease protein
KM415_RS26295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM415_RS26340	COG1609	Transcriptional regulator
KM415_RS26355	COG0739	heme binding
KM415_RS26375	COG2385	sporulation resulting in formation of a cellular spore
KM415_RS26390	COG4836	Membrane
KM415_RS26395	COG1007	ATP synthesis coupled electron transport
KM415_RS26400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM415_RS26405	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM415_RS26415	COG0839	Belongs to the complex I subunit 6 family
KM415_RS26430	COG0649	NAD binding
KM415_RS26435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM415_RS26450	COG3300	MHYT domain
KM415_RS26450	COG5001	Diguanylate cyclase
KM415_RS26500	COG0356	it plays a direct role in the translocation of protons across the membrane
KM415_RS26535	COG0698	ribose 5-phosphate isomerase
KM415_RS26545	COG2190	(PTS) system
KM415_RS26550	COG2259	Doxx family
KM415_RS26555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM415_RS26570	COG0009	L-threonylcarbamoyladenylate synthase
KM415_RS26585	COG2890	protein-(glutamine-N5) methyltransferase activity
KM415_RS26605	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM415_RS26610	COG1494	fructose-1,6-bisphosphatase
KM415_RS26630	COG4821	SIS domain
KM415_RS26640	COG3343	RNA polymerase activity
KM415_RS26650	COG1960	acyl-CoA dehydrogenase activity
KM415_RS26655	COG1960	acyl-CoA dehydrogenase activity
KM415_RS26660	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM415_RS26665	COG0183	Belongs to the thiolase family
KM415_RS26670	COG0247	lactate metabolic process
KM415_RS26670	COG2181	nitrate reductase activity
KM415_RS26675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM415_RS26685	COG5001	Diguanylate cyclase
KM415_RS26685	COG3300	MHYT domain
KM415_RS26705	COG2197	response regulator
KM415_RS26710	COG4585	Histidine kinase
KM415_RS26715	COG0842	Transport permease protein
KM415_RS26720	COG1131	(ABC) transporter
KM415_RS26725	COG0024	Methionine aminopeptidase
KM415_RS26735	COG2234	aminopeptidase activity
KM415_RS26755	COG1595	DNA-templated transcription, initiation
KM415_RS26760	COG0018	arginyl-trna synthetase
KM415_RS26765	COG4506	Protein conserved in bacteria
KM415_RS26770	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM415_RS26785	COG0010	Belongs to the arginase family
KM415_RS26795	COG2814	Major facilitator Superfamily
KM415_RS26800	COG0789	Transcriptional regulator
KM415_RS26805	COG0584	glycerophosphoryl diester phosphodiesterase
KM415_RS26810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM415_RS26820	COG1994	Peptidase M50
KM415_RS26830	COG1078	dGTPase activity
KM415_RS26835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM415_RS26840	COG1120	ATPase activity
KM415_RS26845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM415_RS26870	COG0095	Lipoate-protein ligase
KM415_RS26875	COG0280	phosphate acetyltransferase
KM415_RS26890	COG3773	Cell wall hydrolase
KM415_RS26900	COG2363	Small membrane protein
KM415_RS26910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM415_RS26915	COG2233	PERMEase
KM415_RS26920	COG0561	phosphatase activity
KM415_RS26925	COG2814	Major facilitator Superfamily
KM415_RS26935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM415_RS26940	COG1131	(ABC) transporter
KM415_RS26945	COG2755	lipolytic protein G-D-S-L family
KM415_RS26950	COG1609	Transcriptional regulator
KM415_RS26960	COG0460	homoserine dehydrogenase
KM415_RS26970	COG2873	o-acetylhomoserine
KM415_RS26980	COG1011	Hydrolase
KM415_RS26985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM415_RS26995	COG2197	response regulator
KM415_RS27005	COG0351	phosphomethylpyrimidine kinase
KM415_RS27010	COG3706	GGDEF domain
KM415_RS27015	COG2879	small protein
KM415_RS27020	COG1966	Carbon starvation protein
KM415_RS27025	COG3279	Response regulator of the LytR AlgR family
KM415_RS27030	COG0477	Major facilitator Superfamily
KM415_RS27055	COG0840	transmembrane signaling receptor activity
KM415_RS27065	COG1607	acyl-coa hydrolase
KM415_RS27080	COG0488	(ABC) transporter
KM415_RS27100	COG0463	Glycosyl transferase, family 2
KM415_RS27105	COG1309	transcriptional regulator
KM415_RS27110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM415_RS27115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM415_RS27115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM415_RS27120	COG0628	permease
KM415_RS27135	COG3279	Response regulator of the LytR AlgR family
KM415_RS27140	COG3275	phosphorelay sensor kinase activity
KM415_RS27145	COG2814	Major facilitator Superfamily
KM415_RS27150	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM415_RS27155	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM415_RS27160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM415_RS27180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM415_RS27185	COG1272	protein, Hemolysin III
KM415_RS27205	COG0516	GMP reductase activity
KM415_RS27210	COG1164	Oligoendopeptidase f
KM415_RS27230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM415_RS27235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM415_RS27240	COG4853	Protein conserved in bacteria
KM415_RS27245	COG4863	YycH protein
KM415_RS27250	COG5002	protein histidine kinase activity
KM415_RS27255	COG0745	RESPONSE REGULATOR receiver
KM415_RS27285	COG0305	Participates in initiation and elongation during chromosome replication
KM415_RS27295	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM415_RS27300	COG4241	membrane
KM415_RS27310	COG0629	single-stranded DNA binding
KM415_RS27320	COG0012	GTP binding
KM415_RS27325	COG4481	Protein conserved in bacteria
KM415_RS27330	COG0668	transmembrane transport
KM415_RS27340	COG1475	DNA binding
KM415_RS27345	COG1192	Involved in chromosome partitioning
KM415_RS27370	COG1847	R3H domain protein
KM415_RS27375	COG0706	membrane insertase activity
KM415_RS27385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM415_RS27440	COG3344	reverse transcriptase
KM415_RS27520	COG3344	reverse transcriptase
KM415_RS27725	COG4962	Type ii secretion system protein e
KM415_RS27860	COG2311	Membrane
KM415_RS27880	COG4196	transglutaminase domain protein
KM415_RS27885	COG0671	phosphoesterase, PA-phosphatase related
KM415_RS27905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM415_RS27910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM415_RS28080	COG2002	toxin-antitoxin pair type II binding
KM415_RS28090	COG4974	Belongs to the 'phage' integrase family
KM415_RS28150	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM415_RS28160	COG4974	Belongs to the 'phage' integrase family
KM415_RS28185	COG0457	Tetratricopeptide repeat
KM415_RS28390	COG0741	lytic transglycosylase activity
KM415_RS28390	COG0791	NLP P60 protein
KM415_RS28510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM415_RS28520	COG4166	transmembrane transport
KM415_RS28565	COG1280	lysine exporter protein (LysE YggA)
KM415_RS28590	COG0681	Belongs to the peptidase S26 family
KM415_RS28665	COG1309	transcriptional regulator
KM415_RS28670	COG1683	Conserved Protein
KM415_RS28715	COG1192	Involved in chromosome partitioning