locus-tag	class	description
KM408_RS00010	COG0592	DNA-directed DNA polymerase activity
KM408_RS00015	COG2501	S4 domain
KM408_RS00025	COG0187	DNA topoisomerase II activity
KM408_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM408_RS00065	COG0516	GMP reductase activity
KM408_RS00065	COG0517	IMP dehydrogenase activity
KM408_RS00070	COG1686	Belongs to the peptidase S11 family
KM408_RS00100	COG1428	Deoxynucleoside kinase
KM408_RS00105	COG1428	Deoxynucleoside kinase
KM408_RS00110	COG1335	isochorismatase
KM408_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM408_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM408_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM408_RS00190	COG0470	DNA polymerase III
KM408_RS00195	COG1774	PSP1 C-terminal conserved region
KM408_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM408_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM408_RS00220	COG2002	toxin-antitoxin pair type II binding
KM408_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM408_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM408_RS00230	COG0084	hydrolase, TatD family'
KM408_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM408_RS00250	COG4466	Protein conserved in bacteria
KM408_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM408_RS00270	COG0251	oxidation-reduction process
KM408_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM408_RS00305	COG2002	toxin-antitoxin pair type II binding
KM408_RS00310	COG2244	polysaccharide biosynthetic process
KM408_RS00315	COG3956	TIGRFAM MazG family protein
KM408_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM408_RS00340	COG1098	S1 RNA binding domain
KM408_RS00355	COG2208	phosphoserine phosphatase activity
KM408_RS00360	COG0037	tRNA processing
KM408_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM408_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM408_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM408_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM408_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM408_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM408_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM408_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM408_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM408_RS00420	COG1396	sequence-specific DNA binding
KM408_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM408_RS00455	COG3880	PFAM UvrB UvrC protein
KM408_RS00465	COG0542	response to heat
KM408_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM408_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM408_RS00500	COG1045	serine acetyltransferase
KM408_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM408_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM408_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM408_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM408_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM408_RS00565	COG2813	Specifically methylates the guanine in position
KM408_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM408_RS00580	COG1358	cellular component organization or biogenesis
KM408_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM408_RS00710	COG0201	protein transport
KM408_RS00720	COG0024	Methionine aminopeptidase
KM408_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM408_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM408_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM408_RS00795	COG0489	protein tyrosine kinase activity
KM408_RS00805	COG2194	sulfuric ester hydrolase activity
KM408_RS00810	COG0726	polysaccharide deacetylase
KM408_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM408_RS00895	COG4856	YbbR-like protein
KM408_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM408_RS00915	COG0596	Alpha beta hydrolase
KM408_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM408_RS00940	COG1506	peptidase
KM408_RS00940	COG4946	Tricorn protease homolog
KM408_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM408_RS00975	COG2011	ABC-type metal ion transport system permease component
KM408_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM408_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM408_RS00990	COG0604	alcohol dehydrogenase
KM408_RS01000	COG0277	FAD linked oxidase domain protein
KM408_RS01005	COG2271	Major facilitator Superfamily
KM408_RS01015	COG2814	Major facilitator Superfamily
KM408_RS01030	COG0601	transmembrane transport
KM408_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM408_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM408_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM408_RS01050	COG4166	transmembrane transport
KM408_RS01060	COG2207	Transcriptional regulator
KM408_RS01075	COG4166	transmembrane transport
KM408_RS01080	COG4166	transmembrane transport
KM408_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM408_RS01105	COG4149	molybdate abc transporter
KM408_RS01115	COG1910	domain protein
KM408_RS01125	COG0583	DNA-binding transcription factor activity
KM408_RS01130	COG0697	spore germination
KM408_RS01145	COG0204	Acyl-transferase
KM408_RS01155	COG1609	Transcriptional regulator
KM408_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS01175	COG0084	hydrolase, TatD family'
KM408_RS01180	COG5298	Protein conserved in bacteria
KM408_RS01205	COG0488	(ABC) transporter
KM408_RS01220	COG0747	negative chemotaxis
KM408_RS01225	COG0601	transmembrane transport
KM408_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM408_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM408_RS01240	COG4608	Belongs to the ABC transporter superfamily
KM408_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM408_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM408_RS01290	COG2814	Major facilitator Superfamily
KM408_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM408_RS01310	COG4294	response to UV
KM408_RS01315	COG0705	Rhomboid family
KM408_RS01315	COG0457	Tetratricopeptide repeat
KM408_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM408_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM408_RS01335	COG0864	Transcriptional regulator
KM408_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM408_RS01345	COG2183	response to ionizing radiation
KM408_RS01440	COG0802	atpase or kinase
KM408_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
KM408_RS01450	COG0456	acetyltransferase
KM408_RS01460	COG0488	(ABC) transporter
KM408_RS01475	COG1266	CAAX protease self-immunity
KM408_RS01495	COG2252	PERMEase
KM408_RS01505	COG5002	protein histidine kinase activity
KM408_RS01535	COG2226	methyltransferase
KM408_RS01580	COG1968	undecaprenyl-diphosphatase activity
KM408_RS01595	COG2205	protein histidine kinase activity
KM408_RS01600	COG0745	RESPONSE REGULATOR receiver
KM408_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM408_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM408_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM408_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM408_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM408_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM408_RS01680	COG0151	Belongs to the GarS family
KM408_RS01705	COG0210	DNA helicase
KM408_RS01715	COG4851	CamS sex pheromone cAM373 precursor
KM408_RS01735	COG1335	isochorismatase
KM408_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM408_RS01745	COG2011	ABC-type metal ion transport system permease component
KM408_RS01750	COG1464	Belongs to the NlpA lipoprotein family
KM408_RS01775	COG1846	Transcriptional regulator
KM408_RS01800	COG1597	lipid kinase activity
KM408_RS01805	COG0546	phosphoglycolate phosphatase activity
KM408_RS01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM408_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS01825	COG2076	Multidrug Resistance protein
KM408_RS01830	COG2309	aminopeptidase activity
KM408_RS01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM408_RS01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM408_RS01865	COG4807	Protein conserved in bacteria
KM408_RS01890	COG1757	Na H antiporter
KM408_RS01895	COG1473	amidohydrolase
KM408_RS01910	COG0450	alkyl hydroperoxide reductase
KM408_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS01940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM408_RS01955	COG0166	Belongs to the GPI family
KM408_RS01990	COG5002	protein histidine kinase activity
KM408_RS02010	COG3541	Predicted nucleotidyltransferase
KM408_RS02015	COG2814	Major facilitator Superfamily
KM408_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM408_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
KM408_RS02030	COG0765	amino acid transport
KM408_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM408_RS02045	COG0840	transmembrane signaling receptor activity
KM408_RS02050	COG0840	transmembrane signaling receptor activity
KM408_RS02055	COG0366	Alpha amylase catalytic
KM408_RS02060	COG1263	PTS System
KM408_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM408_RS02060	COG2190	(PTS) system
KM408_RS02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM408_RS02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM408_RS02115	COG1116	anion transmembrane transporter activity
KM408_RS02120	COG0488	(ABC) transporter
KM408_RS02165	COG2270	Major facilitator Superfamily
KM408_RS02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM408_RS02195	COG2310	stress, protein
KM408_RS02200	COG2310	stress, protein
KM408_RS02205	COG2310	stress, protein
KM408_RS02210	COG0861	Integral membrane protein TerC family
KM408_RS02220	COG3853	Toxic anion resistance protein (TelA)
KM408_RS02235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM408_RS02245	COG1295	ribonuclease BN
KM408_RS02250	COG2217	Heavy metal translocating P-type atpase
KM408_RS02255	COG0697	spore germination
KM408_RS02275	COG0586	Pfam SNARE associated Golgi protein
KM408_RS02290	COG3871	stress protein (general stress protein 26)
KM408_RS02295	COG0387	Pfam Sodium calcium exchanger
KM408_RS02305	COG0535	radical SAM domain protein
KM408_RS02330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM408_RS02335	COG0582	viral genome integration into host DNA
KM408_RS02345	COG1396	sequence-specific DNA binding
KM408_RS02360	COG1396	sequence-specific DNA binding
KM408_RS02395	COG1484	DNA-dependent DNA replication
KM408_RS02625	COG0101	tRNA pseudouridine synthase activity
KM408_RS02635	COG3829	transcription factor binding
KM408_RS02645	COG0833	amino acid
KM408_RS02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM408_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM408_RS02680	COG1263	PTS System
KM408_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM408_RS02700	COG0463	Glycosyl transferase, family 2
KM408_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM408_RS02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM408_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM408_RS02745	COG1228	amidohydrolase
KM408_RS02750	COG1090	epimerase
KM408_RS02780	COG1988	membrane-bound metal-dependent
KM408_RS02785	COG1194	a g-specific adenine glycosylase
KM408_RS02810	COG1132	(ABC) transporter
KM408_RS02815	COG4129	membrane
KM408_RS02820	COG0067	glutamate synthase
KM408_RS02820	COG0069	glutamate synthase activity
KM408_RS02820	COG0070	glutamate synthase
KM408_RS02830	COG4555	ABC transporter
KM408_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM408_RS02855	COG0735	belongs to the Fur family
KM408_RS02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM408_RS02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM408_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM408_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM408_RS03005	COG2766	serine protein kinase
KM408_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM408_RS03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM408_RS03040	COG2268	Band 7 protein
KM408_RS03050	COG3290	protein histidine kinase activity
KM408_RS03055	COG4565	transcriptional regulatory protein
KM408_RS03060	COG2851	Citrate transporter
KM408_RS03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM408_RS03085	COG3842	ATPase activity
KM408_RS03090	COG1175	transmembrane transport
KM408_RS03095	COG0395	ABC-type sugar transport system, permease component
KM408_RS03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM408_RS03110	COG0745	RESPONSE REGULATOR receiver
KM408_RS03115	COG5002	protein histidine kinase activity
KM408_RS03125	COG4990	cell redox homeostasis
KM408_RS03135	COG3290	protein histidine kinase activity
KM408_RS03140	COG4565	transcriptional regulatory protein
KM408_RS03145	COG3493	citrate carrier protein
KM408_RS03150	COG0281	malic enzyme
KM408_RS03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS03175	COG5002	protein histidine kinase activity
KM408_RS03180	COG0745	RESPONSE REGULATOR receiver
KM408_RS03185	COG0454	-acetyltransferase
KM408_RS03185	COG0456	acetyltransferase
KM408_RS03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM408_RS03195	COG3383	formate dehydrogenase (NAD+) activity
KM408_RS03215	COG0531	amino acid
KM408_RS03220	COG0640	Transcriptional regulator
KM408_RS03225	COG2217	Heavy metal translocating P-type atpase
KM408_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM408_RS03245	COG3227	Zinc metalloprotease (Elastase)
KM408_RS03265	COG2720	vancomycin resistance protein
KM408_RS03270	COG1316	TRANSCRIPTIONal
KM408_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS03280	COG0346	lactoylglutathione lyase activity
KM408_RS03290	COG1027	Aspartate ammonia-lyase
KM408_RS03295	COG1620	l-lactate permease
KM408_RS03310	COG3104	oligopeptide transport
KM408_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM408_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS03335	COG2226	methyltransferase
KM408_RS03340	COG0156	8-amino-7-oxononanoate synthase activity
KM408_RS03355	COG4548	von Willebrand factor, type A
KM408_RS03360	COG0714	Associated with various cellular activities
KM408_RS03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM408_RS03385	COG0531	amino acid
KM408_RS03390	COG2188	Transcriptional regulator
KM408_RS03395	COG1263	PTS System
KM408_RS03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM408_RS03400	COG0366	Alpha amylase catalytic
KM408_RS03415	COG0697	spore germination
KM408_RS03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM408_RS03430	COG1115	amino acid carrier protein
KM408_RS03435	COG1126	abc transporter atp-binding protein
KM408_RS03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM408_RS03445	COG0765	amino acid transport
KM408_RS03450	COG0765	amino acid transport
KM408_RS03455	COG0833	amino acid
KM408_RS03480	COG2378	regulation of single-species biofilm formation
KM408_RS03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM408_RS03490	COG5002	protein histidine kinase activity
KM408_RS03505	COG0659	secondary active sulfate transmembrane transporter activity
KM408_RS03520	COG0747	negative chemotaxis
KM408_RS03530	COG0601	transmembrane transport
KM408_RS03535	COG4608	Belongs to the ABC transporter superfamily
KM408_RS03545	COG2271	Major facilitator Superfamily
KM408_RS03550	COG1846	Transcriptional regulator
KM408_RS03560	COG1609	Transcriptional regulator
KM408_RS03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM408_RS03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM408_RS03585	COG1879	ABC-type sugar transport system periplasmic component
KM408_RS03610	COG1063	alcohol dehydrogenase
KM408_RS03625	COG3568	Endonuclease Exonuclease Phosphatase
KM408_RS03650	COG1968	undecaprenyl-diphosphatase activity
KM408_RS03655	COG0840	transmembrane signaling receptor activity
KM408_RS03660	COG3584	3D domain protein
KM408_RS03660	COG1388	LysM domain
KM408_RS03665	COG1476	TRANSCRIPTIONal
KM408_RS03680	COG3104	oligopeptide transport
KM408_RS03685	COG1114	Component of the transport system for branched-chain amino acids
KM408_RS03700	COG1113	amino acid transport
KM408_RS03705	COG2252	PERMEase
KM408_RS03730	COG0475	glutathione-regulated potassium exporter activity
KM408_RS03730	COG0569	domain protein
KM408_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM408_RS03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM408_RS03755	COG4990	cell redox homeostasis
KM408_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM408_RS03775	COG0697	spore germination
KM408_RS03780	COG0531	amino acid
KM408_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM408_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM408_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM408_RS03800	COG1918	ferrous iron import across plasma membrane
KM408_RS03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM408_RS03810	COG0573	inorganic phosphate transmembrane transporter activity
KM408_RS03815	COG0581	inorganic phosphate transmembrane transporter activity
KM408_RS03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM408_RS03945	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM408_RS03965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM408_RS03970	COG1116	anion transmembrane transporter activity
KM408_RS03975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM408_RS03980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM408_RS03985	COG0352	thiamine-phosphate diphosphorylase activity
KM408_RS03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM408_RS03995	COG2104	thiamine diphosphate biosynthetic process
KM408_RS04005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM408_RS04010	COG0351	phosphomethylpyrimidine kinase
KM408_RS04050	COG2205	protein histidine kinase activity
KM408_RS04055	COG2814	Major facilitator Superfamily
KM408_RS04060	COG1846	Transcriptional regulator
KM408_RS04075	COG2252	PERMEase
KM408_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM408_RS04100	COG1621	beta-fructofuranosidase activity
KM408_RS04105	COG1263	PTS System
KM408_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM408_RS04110	COG1609	Transcriptional regulator
KM408_RS04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM408_RS04125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM408_RS04160	COG0778	Nitroreductase
KM408_RS04165	COG2719	SpoVR family
KM408_RS04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM408_RS04195	COG1937	Protein conserved in bacteria
KM408_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
KM408_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM408_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM408_RS04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
KM408_RS04225	COG2210	Belongs to the sulfur carrier protein TusA family
KM408_RS04230	COG0730	response to heat
KM408_RS04240	COG1316	TRANSCRIPTIONal
KM408_RS04245	COG0604	alcohol dehydrogenase
KM408_RS04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM408_RS04265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM408_RS04265	COG3711	transcriptional antiterminator
KM408_RS04270	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM408_RS04275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM408_RS04295	COG1388	LysM domain
KM408_RS04295	COG3584	3D domain protein
KM408_RS04300	COG0577	efflux transmembrane transporter activity
KM408_RS04305	COG1136	(ABC) transporter
KM408_RS04315	COG5522	Integral membrane protein (intg_mem_TP0381)
KM408_RS04330	COG1114	Component of the transport system for branched-chain amino acids
KM408_RS04335	COG3546	catalase activity
KM408_RS04370	COG0586	Pfam SNARE associated Golgi protein
KM408_RS04405	COG0531	amino acid
KM408_RS04410	COG0475	glutathione-regulated potassium exporter activity
KM408_RS04420	COG1737	Transcriptional regulator
KM408_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM408_RS04430	COG1263	PTS System
KM408_RS04440	COG2259	Doxx family
KM408_RS04455	COG0697	spore germination
KM408_RS04460	COG1522	sequence-specific DNA binding
KM408_RS04475	COG2076	Multidrug Resistance protein
KM408_RS04480	COG1309	transcriptional regulator
KM408_RS04485	COG2814	Major facilitator Superfamily
KM408_RS04490	COG1733	regulation of RNA biosynthetic process
KM408_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM408_RS04505	COG4533	DNA binding
KM408_RS04510	COG2211	Major facilitator Superfamily
KM408_RS04520	COG0693	protein deglycase activity
KM408_RS04525	COG0753	catalase activity
KM408_RS04525	COG0693	protein deglycase activity
KM408_RS04535	COG0531	amino acid
KM408_RS04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM408_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS04555	COG1132	(ABC) transporter
KM408_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM408_RS04570	COG0765	amino acid transport
KM408_RS04575	COG1126	abc transporter atp-binding protein
KM408_RS04590	COG0189	ligase activity
KM408_RS04620	COG0028	Belongs to the TPP enzyme family
KM408_RS04625	COG3527	Alpha-acetolactate decarboxylase
KM408_RS04640	COG0561	phosphatase activity
KM408_RS04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM408_RS04670	COG0659	secondary active sulfate transmembrane transporter activity
KM408_RS04690	COG0653	protein targeting
KM408_RS04695	COG2244	polysaccharide biosynthetic process
KM408_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM408_RS04710	COG4196	transglutaminase domain protein
KM408_RS04725	COG1696	Membrane protein involved in D-alanine export
KM408_RS04740	COG1024	Enoyl-CoA hydratase
KM408_RS04760	COG1363	Peptidase, m42
KM408_RS04780	COG3938	Belongs to the proline racemase family
KM408_RS04820	COG0601	transmembrane transport
KM408_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM408_RS04835	COG4608	Belongs to the ABC transporter superfamily
KM408_RS04870	COG0477	Major facilitator Superfamily
KM408_RS04875	COG3290	protein histidine kinase activity
KM408_RS04880	COG4565	transcriptional regulatory protein
KM408_RS04885	COG3181	Tripartite tricarboxylate transporter family receptor
KM408_RS04915	COG4978	Transcriptional regulator
KM408_RS04915	COG0789	Transcriptional regulator
KM408_RS04930	COG0305	Participates in initiation and elongation during chromosome replication
KM408_RS04970	COG0477	Major facilitator Superfamily
KM408_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM408_RS05015	COG3320	Male sterility
KM408_RS05020	COG1309	transcriptional regulator
KM408_RS05040	COG1183	phosphatidylcholine synthase activity
KM408_RS05060	COG2376	Dihydroxyacetone kinase
KM408_RS05070	COG2376	Dihydroxyacetone kinase
KM408_RS05075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM408_RS05080	COG1959	2 iron, 2 sulfur cluster binding
KM408_RS05110	COG3437	response regulator, receiver
KM408_RS05110	COG2770	Histidine kinase
KM408_RS05165	COG3237	CsbD-like
KM408_RS05190	COG1191	sigma factor activity
KM408_RS05200	COG2208	phosphoserine phosphatase activity
KM408_RS05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM408_RS05210	COG2198	Histidine kinase
KM408_RS05210	COG0784	Response regulator, receiver
KM408_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM408_RS05210	COG2205	protein histidine kinase activity
KM408_RS05265	COG0420	3'-5' exonuclease activity
KM408_RS05290	COG1309	transcriptional regulator
KM408_RS05295	COG2814	Major facilitator Superfamily
KM408_RS05300	COG0346	lactoylglutathione lyase activity
KM408_RS05310	COG0457	Tetratricopeptide repeat
KM408_RS05315	COG2267	carboxylic ester hydrolase activity
KM408_RS05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM408_RS05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM408_RS05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM408_RS05390	COG0477	Major facilitator Superfamily
KM408_RS05395	COG0477	Major facilitator Superfamily
KM408_RS05405	COG3973	AAA domain
KM408_RS05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM408_RS05430	COG4980	gas vesicle protein
KM408_RS05435	COG0537	adenosine 5'-monophosphoramidase activity
KM408_RS05440	COG1131	(ABC) transporter
KM408_RS05445	COG4473	ABC transporter
KM408_RS05460	COG1309	transcriptional regulator
KM408_RS05470	COG3402	PFAM membrane-flanked domain
KM408_RS05515	COG3402	PFAM membrane-flanked domain
KM408_RS05520	COG3428	Bacterial PH domain
KM408_RS05525	COG2329	Antibiotic biosynthesis monooxygenase
KM408_RS05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM408_RS05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM408_RS05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM408_RS05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM408_RS05580	COG1309	transcriptional regulator
KM408_RS05585	COG1511	domain protein
KM408_RS05610	COG1609	Transcriptional regulator
KM408_RS05620	COG1234	tRNA 3'-trailer cleavage
KM408_RS05625	COG0095	Lipoate-protein ligase
KM408_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
KM408_RS05665	COG3209	COG3209 Rhs family protein
KM408_RS05705	COG1078	dGTPase activity
KM408_RS05715	COG1595	DNA-templated transcription, initiation
KM408_RS05720	COG2207	Transcriptional regulator
KM408_RS05720	COG3708	Transcriptional regulator
KM408_RS05735	COG2205	protein histidine kinase activity
KM408_RS05740	COG0745	RESPONSE REGULATOR receiver
KM408_RS05765	COG0501	Belongs to the peptidase M48B family
KM408_RS05770	COG0840	transmembrane signaling receptor activity
KM408_RS05775	COG0697	spore germination
KM408_RS05795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM408_RS05800	COG2224	Isocitrate lyase
KM408_RS05825	COG4903	ComK protein
KM408_RS05830	COG0398	Pfam SNARE associated Golgi protein
KM408_RS05840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM408_RS05845	COG1074	ATP-dependent DNA helicase activity
KM408_RS05890	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM408_RS05915	COG0367	asparagine synthase
KM408_RS05920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM408_RS05925	COG0753	catalase activity
KM408_RS05930	COG0004	ammonium transporteR
KM408_RS05950	COG2996	Protein conserved in bacteria
KM408_RS05960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM408_RS05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS05985	COG0561	phosphatase activity
KM408_RS05995	COG0542	response to heat
KM408_RS06005	COG2267	carboxylic ester hydrolase activity
KM408_RS06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM408_RS06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM408_RS06030	COG5504	Zn-dependent protease
KM408_RS06040	COG0180	Tryptophanyl-tRNA synthetase
KM408_RS06050	COG4166	transmembrane transport
KM408_RS06055	COG0601	transmembrane transport
KM408_RS06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM408_RS06065	COG0444	Belongs to the ABC transporter superfamily
KM408_RS06070	COG4608	Belongs to the ABC transporter superfamily
KM408_RS06075	COG0534	Mate efflux family protein
KM408_RS06080	COG4166	transmembrane transport
KM408_RS06095	COG0861	Integral membrane protein TerC family
KM408_RS06100	COG4862	establishment of competence for transformation
KM408_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM408_RS06115	COG1164	Oligoendopeptidase f
KM408_RS06125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM408_RS06130	COG2346	COG2346, Truncated hemoglobins
KM408_RS06135	COG4116	CYTH
KM408_RS06145	COG2357	RelA SpoT domain protein
KM408_RS06155	COG0564	pseudouridine synthase activity
KM408_RS06175	COG1216	Glycosyl transferase, family 2
KM408_RS06175	COG0463	Glycosyl transferase, family 2
KM408_RS06195	COG0457	Tetratricopeptide repeat
KM408_RS06195	COG0463	Glycosyl transferase, family 2
KM408_RS06215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM408_RS06230	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM408_RS06275	COG2153	protein acetylation
KM408_RS06285	COG2382	esterase
KM408_RS06300	COG5492	domain, Protein
KM408_RS06305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM408_RS06315	COG0512	Glutamine amidotransferase of anthranilate synthase
KM408_RS06315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM408_RS06350	COG1620	l-lactate permease
KM408_RS06355	COG5634	Uncharacterized conserved protein (DUF2278)
KM408_RS06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM408_RS06420	COG1476	TRANSCRIPTIONal
KM408_RS06480	COG2226	methyltransferase
KM408_RS06490	COG1686	Belongs to the peptidase S11 family
KM408_RS06495	COG0681	Belongs to the peptidase S26 family
KM408_RS06530	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS06535	COG3842	ATPase activity
KM408_RS06540	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM408_RS06545	COG1177	transmembrane transport
KM408_RS06550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM408_RS06560	COG2409	Drug exporters of the RND superfamily
KM408_RS06570	COG0564	pseudouridine synthase activity
KM408_RS06580	COG2340	Cysteine-rich secretory protein family
KM408_RS06585	COG0247	lactate metabolic process
KM408_RS06590	COG0277	FAD linked oxidase domain protein
KM408_RS06595	COG3835	regulator
KM408_RS06605	COG0745	RESPONSE REGULATOR receiver
KM408_RS06610	COG5002	protein histidine kinase activity
KM408_RS06615	COG2186	Transcriptional regulator
KM408_RS06635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM408_RS06645	COG2116	formate transmembrane transporter activity
KM408_RS06650	COG0861	Integral membrane protein TerC family
KM408_RS06655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM408_RS06665	COG2030	dehydratase
KM408_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS06690	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM408_RS06695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM408_RS06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM408_RS06715	COG1840	ABC-type Fe3 transport system, periplasmic component
KM408_RS06745	COG1349	DNA-binding transcription factor activity
KM408_RS06765	COG2861	carbohydrate metabolic process
KM408_RS06775	COG3852	Histidine kinase
KM408_RS06780	COG1846	Transcriptional regulator
KM408_RS06790	COG2318	DinB family
KM408_RS06800	COG5002	protein histidine kinase activity
KM408_RS06810	COG0720	synthase
KM408_RS06825	COG4873	Protein conserved in bacteria
KM408_RS06855	COG1780	Probably involved in ribonucleotide reductase function
KM408_RS06875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM408_RS06880	COG1725	Transcriptional regulator
KM408_RS06885	COG1131	(ABC) transporter
KM408_RS06895	COG1131	(ABC) transporter
KM408_RS06900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM408_RS06915	COG1522	sequence-specific DNA binding
KM408_RS06925	COG1335	isochorismatase
KM408_RS06935	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM408_RS06940	COG2070	2-Nitropropane dioxygenase
KM408_RS06945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM408_RS06955	COG1696	Membrane protein involved in D-alanine export
KM408_RS06980	COG0716	FMN binding
KM408_RS06995	COG3173	Aminoglycoside phosphotransferase
KM408_RS07015	COG0534	Mate efflux family protein
KM408_RS07020	COG1968	undecaprenyl-diphosphatase activity
KM408_RS07035	COG1846	Transcriptional regulator
KM408_RS07045	COG1301	dicarboxylic acid transport
KM408_RS07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM408_RS07055	COG4709	membrane
KM408_RS07060	COG3874	Sporulation protein YtfJ
KM408_RS07085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM408_RS07090	COG0028	Belongs to the TPP enzyme family
KM408_RS07095	COG0440	acetolactate synthase activity
KM408_RS07100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM408_RS07110	COG0473	3-isopropylmalate dehydrogenase activity
KM408_RS07135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM408_RS07170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM408_RS07185	COG1183	phosphatidylcholine synthase activity
KM408_RS07190	COG1368	sulfuric ester hydrolase activity
KM408_RS07200	COG0019	diaminopimelate decarboxylase activity
KM408_RS07220	COG0529	Catalyzes the synthesis of activated sulfate
KM408_RS07225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM408_RS07245	COG1648	precorrin-2 dehydrogenase activity
KM408_RS07250	COG0733	neurotransmitter:sodium symporter activity
KM408_RS07270	COG1757	Na H antiporter
KM408_RS07285	COG4758	membrane
KM408_RS07290	COG4585	Histidine kinase
KM408_RS07295	COG2197	response regulator
KM408_RS07305	COG1114	Component of the transport system for branched-chain amino acids
KM408_RS07315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM408_RS07340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM408_RS07340	COG1017	nitric oxide dioxygenase activity
KM408_RS07355	COG0730	response to heat
KM408_RS07360	COG0306	phosphate transporter
KM408_RS07365	COG1392	Phosphate transport regulator
KM408_RS07370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM408_RS07385	COG3852	Histidine kinase
KM408_RS07390	COG1801	Protein of unknown function DUF72
KM408_RS07400	COG0582	viral genome integration into host DNA
KM408_RS07405	COG5002	protein histidine kinase activity
KM408_RS07425	COG0392	lysyltransferase activity
KM408_RS07425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM408_RS07440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM408_RS07445	COG1686	Belongs to the peptidase S11 family
KM408_RS07450	COG2715	membrane protein required for spore maturation
KM408_RS07455	COG0700	Nucleoside recognition
KM408_RS07460	COG1187	pseudouridine synthase activity
KM408_RS07470	COG1333	cytochrome c biogenesis protein
KM408_RS07475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM408_RS07480	COG0745	RESPONSE REGULATOR receiver
KM408_RS07485	COG5002	protein histidine kinase activity
KM408_RS07490	COG2096	Adenosyltransferase
KM408_RS07505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM408_RS07510	COG1141	Ferredoxin
KM408_RS07515	COG4955	Helix-turn-helix domain
KM408_RS07520	COG0514	ATP-dependent DNA helicase (RecQ)
KM408_RS07525	COG1266	CAAX protease self-immunity
KM408_RS07545	COG4862	establishment of competence for transformation
KM408_RS07550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM408_RS07570	COG0492	ferredoxin-NADP+ reductase activity
KM408_RS07575	COG0252	asparaginase activity
KM408_RS07645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM408_RS07660	COG0142	geranyltranstransferase activity
KM408_RS07670	COG0142	geranyltranstransferase activity
KM408_RS07690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM408_RS07695	COG0457	Tetratricopeptide repeat
KM408_RS07715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM408_RS07725	COG4347	Protein of unknown function (DUF1405)
KM408_RS07740	COG2738	Putative neutral zinc metallopeptidase
KM408_RS07750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS07755	COG1694	Mazg nucleotide pyrophosphohydrolase
KM408_RS07770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM408_RS07775	COG0438	transferase activity, transferring glycosyl groups
KM408_RS07810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM408_RS07810	COG1199	ATP-dependent helicase activity
KM408_RS07830	COG3935	DnaD domain protein
KM408_RS07835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM408_RS07845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM408_RS07845	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM408_RS07905	COG0116	Belongs to the methyltransferase superfamily
KM408_RS07915	COG1199	ATP-dependent helicase activity
KM408_RS07920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM408_RS07930	COG3173	Aminoglycoside phosphotransferase
KM408_RS07935	COG0024	Methionine aminopeptidase
KM408_RS07945	COG2233	PERMEase
KM408_RS07950	COG2311	Membrane
KM408_RS07955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM408_RS07965	COG0456	acetyltransferase
KM408_RS08015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM408_RS08040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM408_RS08055	COG1215	transferase activity, transferring glycosyl groups
KM408_RS08060	COG0438	transferase activity, transferring glycosyl groups
KM408_RS08075	COG0454	-acetyltransferase
KM408_RS08095	COG0328	RNA-DNA hybrid ribonuclease activity
KM408_RS08135	COG1280	lysine exporter protein (LysE YggA)
KM408_RS08150	COG3162	membrane
KM408_RS08155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM408_RS08160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM408_RS08170	COG0475	glutathione-regulated potassium exporter activity
KM408_RS08175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM408_RS08180	COG0789	Transcriptional regulator
KM408_RS08180	COG4978	Transcriptional regulator
KM408_RS08190	COG2323	membrane
KM408_RS08195	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM408_RS08250	COG1923	regulation of RNA biosynthetic process
KM408_RS08260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM408_RS08265	COG1360	Flagellar Motor Protein
KM408_RS08270	COG2201	protein-glutamate methylesterase activity
KM408_RS08280	COG1776	CheC inhibitor of MCP methylation
KM408_RS08280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM408_RS08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM408_RS08315	COG1256	bacterial-type flagellum assembly
KM408_RS08340	COG1815	bacterial-type flagellum-dependent cell motility
KM408_RS08345	COG1558	bacterial-type flagellum-dependent cell motility
KM408_RS08360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM408_RS08370	COG1157	protein secretion by the type III secretion system
KM408_RS08405	COG0835	chemotaxis
KM408_RS08405	COG0784	Response regulator, receiver
KM408_RS08415	COG0463	Glycosyl transferase, family 2
KM408_RS08445	COG0457	Tetratricopeptide repeat
KM408_RS08445	COG0463	Glycosyl transferase, family 2
KM408_RS08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM408_RS08465	COG0741	lytic transglycosylase activity
KM408_RS08480	COG1776	CheC inhibitor of MCP methylation
KM408_RS08480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM408_RS08490	COG1338	Plays a role in the flagellum-specific transport system
KM408_RS08495	COG1987	bacterial-type flagellum assembly
KM408_RS08505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM408_RS08510	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM408_RS08515	COG1419	protein localization to endoplasmic reticulum
KM408_RS08520	COG4786	Flagellar basal body rod
KM408_RS08525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM408_RS08550	COG1309	transcriptional regulator
KM408_RS08570	COG2329	Antibiotic biosynthesis monooxygenase
KM408_RS08595	COG0583	DNA-binding transcription factor activity
KM408_RS08605	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM408_RS08615	COG1234	tRNA 3'-trailer cleavage
KM408_RS08640	COG1686	Belongs to the peptidase S11 family
KM408_RS08650	COG0406	alpha-ribazole phosphatase activity
KM408_RS08680	COG0367	asparagine synthase
KM408_RS08710	COG1802	Transcriptional regulator
KM408_RS08715	COG0697	spore germination
KM408_RS08720	COG0523	cobalamin synthesis protein
KM408_RS08725	COG0701	Predicted permease
KM408_RS08735	COG1216	Glycosyl transferase, family 2
KM408_RS08735	COG0438	transferase activity, transferring glycosyl groups
KM408_RS08740	COG1757	Na H antiporter
KM408_RS08745	COG0114	fumarate hydratase activity
KM408_RS08770	COG3340	Belongs to the peptidase S51 family
KM408_RS08790	COG0785	Cytochrome C biogenesis protein
KM408_RS08820	COG2733	membrane
KM408_RS08855	COG1131	(ABC) transporter
KM408_RS08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM408_RS08875	COG0528	UMP kinase activity
KM408_RS08885	COG1027	Aspartate ammonia-lyase
KM408_RS08890	COG0281	malic enzyme
KM408_RS08895	COG4191	Histidine kinase
KM408_RS08900	COG0784	Response regulator, receiver
KM408_RS08905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM408_RS08965	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM408_RS08975	COG2814	Major facilitator Superfamily
KM408_RS08990	COG1966	Carbon starvation protein
KM408_RS09005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM408_RS09015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM408_RS09025	COG2223	nitrite transmembrane transporter activity
KM408_RS09030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM408_RS09045	COG2244	polysaccharide biosynthetic process
KM408_RS09050	COG0733	neurotransmitter:sodium symporter activity
KM408_RS09060	COG5566	PFAM Mor transcription activator
KM408_RS09065	COG2323	membrane
KM408_RS09085	COG2084	Dehydrogenase
KM408_RS09100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM408_RS09110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM408_RS09115	COG0028	Belongs to the TPP enzyme family
KM408_RS09120	COG0440	acetolactate synthase activity
KM408_RS09125	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM408_RS09135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM408_RS09160	COG2814	Major facilitator Superfamily
KM408_RS09165	COG3384	dioxygenase
KM408_RS09175	COG3279	Response regulator of the LytR AlgR family
KM408_RS09180	COG0427	acetyl-CoA hydrolase
KM408_RS09200	COG1073	alpha beta
KM408_RS09230	COG0535	radical SAM domain protein
KM408_RS09235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS09255	COG1914	H( )-stimulated, divalent metal cation uptake system
KM408_RS09270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM408_RS09300	COG2390	Transcriptional regulator
KM408_RS09310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS09315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM408_RS09330	COG4224	UPF0291 protein
KM408_RS09350	COG0006	proline dipeptidase activity
KM408_RS09355	COG2132	Multicopper oxidase
KM408_RS09370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM408_RS09385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM408_RS09400	COG2372	response to copper ion
KM408_RS09400	COG1276	copper resistance
KM408_RS09405	COG4549	nuclear export factor GLE1
KM408_RS09415	COG0697	spore germination
KM408_RS09420	COG0583	DNA-binding transcription factor activity
KM408_RS09425	COG1959	2 iron, 2 sulfur cluster binding
KM408_RS09430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM408_RS09435	COG0778	Nitroreductase
KM408_RS09445	COG0628	permease
KM408_RS09455	COG1231	oxidoreductase activity
KM408_RS09460	COG0523	cobalamin synthesis protein
KM408_RS09475	COG0318	PFAM AMP-dependent synthetase and ligase
KM408_RS09480	COG2030	dehydratase
KM408_RS09485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM408_RS09495	COG0411	ABC transporter
KM408_RS09515	COG0583	DNA-binding transcription factor activity
KM408_RS09525	COG1942	4-Oxalocrotonate Tautomerase
KM408_RS09535	COG1846	Transcriptional regulator
KM408_RS09545	COG1271	oxidase subunit
KM408_RS09550	COG1294	oxidase, subunit
KM408_RS09555	COG4988	ABC transporter
KM408_RS09560	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM408_RS09580	COG1686	Belongs to the peptidase S11 family
KM408_RS09595	COG1388	LysM domain
KM408_RS09595	COG0791	NLP P60 protein
KM408_RS09610	COG0745	RESPONSE REGULATOR receiver
KM408_RS09615	COG5002	protein histidine kinase activity
KM408_RS09625	COG0300	oxidoreductase activity
KM408_RS09660	COG0460	homoserine dehydrogenase
KM408_RS09685	COG1316	TRANSCRIPTIONal
KM408_RS09695	COG0745	RESPONSE REGULATOR receiver
KM408_RS09700	COG5002	protein histidine kinase activity
KM408_RS09715	COG1285	pathogenesis
KM408_RS09720	COG1247	-acetyltransferase
KM408_RS09740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM408_RS09750	COG1082	Xylose isomerase domain protein TIM barrel
KM408_RS09765	COG1279	arginine transmembrane transporter activity
KM408_RS09775	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM408_RS09815	COG2002	toxin-antitoxin pair type II binding
KM408_RS09820	COG1404	Belongs to the peptidase S8 family
KM408_RS09825	COG0640	Transcriptional regulator
KM408_RS09830	COG0667	Aldo Keto reductase
KM408_RS09835	COG2814	Major facilitator Superfamily
KM408_RS09860	COG0840	transmembrane signaling receptor activity
KM408_RS09875	COG3949	Membrane
KM408_RS09880	COG0783	Belongs to the Dps family
KM408_RS09895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM408_RS09905	COG1231	oxidoreductase activity
KM408_RS09915	COG4989	oxidoreductase activity
KM408_RS09920	COG0523	cobalamin synthesis protein
KM408_RS09925	COG0456	acetyltransferase
KM408_RS09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM408_RS09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM408_RS09995	COG0702	epimerase
KM408_RS10005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM408_RS10015	COG4166	transmembrane transport
KM408_RS10030	COG0406	alpha-ribazole phosphatase activity
KM408_RS10040	COG5337	Spore coat protein CotH
KM408_RS10045	COG1051	belongs to the nudix hydrolase family
KM408_RS10050	COG0586	Pfam SNARE associated Golgi protein
KM408_RS10055	COG2244	polysaccharide biosynthetic process
KM408_RS10065	COG0701	Predicted permease
KM408_RS10070	COG3689	TIGRFAM TIGR03943 family protein
KM408_RS10075	COG1607	acyl-coa hydrolase
KM408_RS10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM408_RS10100	COG0702	epimerase
KM408_RS10105	COG2839	Protein conserved in bacteria
KM408_RS10110	COG1253	flavin adenine dinucleotide binding
KM408_RS10125	COG1114	Component of the transport system for branched-chain amino acids
KM408_RS10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM408_RS10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM408_RS10160	COG1876	peptidase activity
KM408_RS10170	COG0154	amidase activity
KM408_RS10175	COG2211	Major facilitator Superfamily
KM408_RS10195	COG0561	phosphatase activity
KM408_RS10205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM408_RS10210	COG4106	trans-aconitate 2-methyltransferase activity
KM408_RS10225	COG1819	glycosyl
KM408_RS10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS10270	COG0456	acetyltransferase
KM408_RS10325	COG3874	Sporulation protein YtfJ
KM408_RS10350	COG2226	methyltransferase
KM408_RS10375	COG0346	lactoylglutathione lyase activity
KM408_RS10385	COG0604	alcohol dehydrogenase
KM408_RS10390	COG1595	DNA-templated transcription, initiation
KM408_RS10415	COG0386	Belongs to the glutathione peroxidase family
KM408_RS10420	COG1305	Transglutaminase-like
KM408_RS10425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM408_RS10430	COG0714	Associated with various cellular activities
KM408_RS10445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM408_RS10450	COG1140	nitrate reductase beta subunit
KM408_RS10455	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM408_RS10460	COG2181	nitrate reductase activity
KM408_RS10480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM408_RS10485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM408_RS10490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM408_RS10495	COG0303	'Molybdopterin
KM408_RS10500	COG0314	molybdopterin synthase activity
KM408_RS10510	COG2223	nitrite transmembrane transporter activity
KM408_RS10525	COG1648	precorrin-2 dehydrogenase activity
KM408_RS10535	COG1587	Uroporphyrinogen-III synthase
KM408_RS10535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM408_RS10540	COG2146	nitrite reductase [NAD(P)H] activity
KM408_RS10545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM408_RS10550	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM408_RS10585	COG2359	stage V sporulation protein S
KM408_RS10610	COG1418	mRNA catabolic process
KM408_RS10615	COG0488	(ABC) transporter
KM408_RS10630	COG0629	single-stranded DNA binding
KM408_RS10645	COG1413	lyase activity
KM408_RS10660	COG2521	methyltransferase
KM408_RS10660	COG2136	Putative SAM-dependent methyltransferase
KM408_RS10665	COG0018	arginyl-trna synthetase
KM408_RS10690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM408_RS10710	COG0017	Asparaginyl-tRNA synthetase
KM408_RS10730	COG1674	ftsk spoiiie
KM408_RS10800	COG1929	Belongs to the glycerate kinase type-1 family
KM408_RS10805	COG0471	metal ion transport
KM408_RS10810	COG0745	RESPONSE REGULATOR receiver
KM408_RS10815	COG3850	Histidine kinase
KM408_RS10815	COG5002	protein histidine kinase activity
KM408_RS10830	COG0733	neurotransmitter:sodium symporter activity
KM408_RS10855	COG2610	gluconate transmembrane transporter activity
KM408_RS10860	COG1454	alcohol dehydrogenase
KM408_RS10865	COG1794	racemase activity, acting on amino acids and derivatives
KM408_RS10875	COG0456	acetyltransferase
KM408_RS10890	COG1131	(ABC) transporter
KM408_RS10905	COG0546	phosphoglycolate phosphatase activity
KM408_RS10925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM408_RS10940	COG0768	penicillin binding
KM408_RS10945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM408_RS10950	COG0204	Acyl-transferase
KM408_RS10955	COG1272	protein, Hemolysin III
KM408_RS10965	COG0805	protein transport
KM408_RS10975	COG1307	EDD domain protein, DegV family
KM408_RS10980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM408_RS10985	COG1999	signal sequence binding
KM408_RS10990	COG0071	Belongs to the small heat shock protein (HSP20) family
KM408_RS10995	COG0367	asparagine synthase
KM408_RS11010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM408_RS11015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM408_RS11050	COG0668	transmembrane transport
KM408_RS11055	COG2203	Gaf domain
KM408_RS11055	COG4585	Histidine kinase
KM408_RS11060	COG2197	response regulator
KM408_RS11070	COG1064	alcohol dehydrogenase
KM408_RS11125	COG1125	glycine betaine transport
KM408_RS11125	COG0517	IMP dehydrogenase activity
KM408_RS11130	COG1174	glycine betaine transport
KM408_RS11165	COG1253	flavin adenine dinucleotide binding
KM408_RS11170	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS11175	COG5506	Protein of unknown function (DUF1694)
KM408_RS11190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM408_RS11195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM408_RS11200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM408_RS11205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM408_RS11210	COG0456	acetyltransferase
KM408_RS11215	COG3829	transcription factor binding
KM408_RS11220	COG1509	lysine 2,3-aminomutase activity
KM408_RS11260	COG4326	sporulation control protein
KM408_RS11265	COG0671	phosphoesterase, PA-phosphatase related
KM408_RS11270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM408_RS11275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM408_RS11305	COG1715	Restriction endonuclease
KM408_RS11305	COG1787	Restriction endonuclease
KM408_RS11395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM408_RS11445	COG2814	Major facilitator Superfamily
KM408_RS11450	COG4841	protein insertion into membrane
KM408_RS11455	COG0372	Belongs to the citrate synthase family
KM408_RS11460	COG2079	MmgE PrpD family protein
KM408_RS11465	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM408_RS11470	COG1960	acyl-CoA dehydrogenase activity
KM408_RS11475	COG2084	Dehydrogenase
KM408_RS11485	COG1280	lysine exporter protein (LysE YggA)
KM408_RS11490	COG1024	Enoyl-CoA hydratase
KM408_RS11505	COG0420	3'-5' exonuclease activity
KM408_RS11510	COG0419	ATPase involved in DNA repair
KM408_RS11535	COG2223	nitrite transmembrane transporter activity
KM408_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS11545	COG1169	isochorismate synthase
KM408_RS11550	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM408_RS11555	COG1535	isochorismatase
KM408_RS11555	COG3433	isochorismatase activity
KM408_RS11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM408_RS11565	COG3251	PFAM MbtH domain protein
KM408_RS11570	COG2814	Major facilitator Superfamily
KM408_RS11585	COG0776	regulation of translation
KM408_RS11595	COG2318	DinB family
KM408_RS11605	COG1115	amino acid carrier protein
KM408_RS11620	COG2329	Antibiotic biosynthesis monooxygenase
KM408_RS11625	COG1187	pseudouridine synthase activity
KM408_RS11630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM408_RS11645	COG0596	Alpha beta hydrolase
KM408_RS11650	COG2814	Major facilitator Superfamily
KM408_RS11670	COG2226	methyltransferase
KM408_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS11750	COG1247	-acetyltransferase
KM408_RS11780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM408_RS11790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS11800	COG1278	Cold shock
KM408_RS11815	COG0010	Belongs to the arginase family
KM408_RS11820	COG0561	phosphatase activity
KM408_RS11865	COG0583	DNA-binding transcription factor activity
KM408_RS11870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM408_RS11885	COG0583	DNA-binding transcription factor activity
KM408_RS11890	COG2258	MOSC domain
KM408_RS11905	COG1132	(ABC) transporter
KM408_RS11910	COG1132	(ABC) transporter
KM408_RS11930	COG1396	sequence-specific DNA binding
KM408_RS11955	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM408_RS11960	COG1595	DNA-templated transcription, initiation
KM408_RS11985	COG1649	PFAM Uncharacterised BCR, COG1649
KM408_RS12010	COG2971	BadF BadG BcrA BcrD
KM408_RS12015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM408_RS12020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM408_RS12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS12070	COG1309	transcriptional regulator
KM408_RS12085	COG0577	efflux transmembrane transporter activity
KM408_RS12085	COG1136	(ABC) transporter
KM408_RS12090	COG3615	Tellurite resistance protein tehB
KM408_RS12090	COG0500	methyltransferase
KM408_RS12100	COG2226	methyltransferase
KM408_RS12105	COG3961	Belongs to the TPP enzyme family
KM408_RS12110	COG1846	Transcriptional regulator
KM408_RS12150	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM408_RS12165	COG1595	DNA-templated transcription, initiation
KM408_RS12175	COG0768	penicillin binding
KM408_RS12185	COG2367	Beta-lactamase
KM408_RS12190	COG0671	phosphoesterase, PA-phosphatase related
KM408_RS12195	COG1609	Transcriptional regulator
KM408_RS12200	COG2814	Major facilitator Superfamily
KM408_RS12205	COG0673	inositol 2-dehydrogenase activity
KM408_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS12230	COG0191	fructose-bisphosphate aldolase activity
KM408_RS12235	COG3718	enzyme involved in inositol metabolism
KM408_RS12260	COG0457	Tetratricopeptide repeat
KM408_RS12265	COG1476	TRANSCRIPTIONal
KM408_RS12280	COG1876	peptidase activity
KM408_RS12300	COG1309	transcriptional regulator
KM408_RS12305	COG0488	(ABC) transporter
KM408_RS12320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS12335	COG1252	NADH dehydrogenase
KM408_RS12340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM408_RS12355	COG1131	(ABC) transporter
KM408_RS12365	COG1309	transcriptional regulator
KM408_RS12380	COG1960	acyl-CoA dehydrogenase activity
KM408_RS12385	COG0439	Biotin carboxylase
KM408_RS12390	COG0511	ligase activity, forming carbon-carbon bonds
KM408_RS12395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM408_RS12400	COG1024	Enoyl-CoA hydratase
KM408_RS12405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM408_RS12410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM408_RS12420	COG1247	-acetyltransferase
KM408_RS12425	COG0572	uridine kinase
KM408_RS12435	COG2318	DinB family
KM408_RS12440	COG1686	Belongs to the peptidase S11 family
KM408_RS12465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM408_RS12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM408_RS12505	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM408_RS12530	COG2814	Major facilitator Superfamily
KM408_RS12550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM408_RS12570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS12585	COG1063	alcohol dehydrogenase
KM408_RS12600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM408_RS12605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM408_RS12620	COG3773	Cell wall hydrolase
KM408_RS12630	COG0745	RESPONSE REGULATOR receiver
KM408_RS12645	COG0488	(ABC) transporter
KM408_RS12660	COG1136	(ABC) transporter
KM408_RS12685	COG0460	homoserine dehydrogenase
KM408_RS12690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS12700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM408_RS12765	COG2124	cytochrome p450
KM408_RS12800	COG0561	phosphatase activity
KM408_RS12810	COG0768	penicillin binding
KM408_RS12815	COG1819	glycosyl
KM408_RS12820	COG1794	racemase activity, acting on amino acids and derivatives
KM408_RS12830	COG1122	ATPase activity
KM408_RS12845	COG2205	protein histidine kinase activity
KM408_RS12855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM408_RS12860	COG0604	alcohol dehydrogenase
KM408_RS12865	COG0768	penicillin binding
KM408_RS12875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM408_RS12910	COG0693	protein deglycase activity
KM408_RS12940	COG2814	Major facilitator Superfamily
KM408_RS12955	COG0584	glycerophosphoryl diester phosphodiesterase
KM408_RS12975	COG0697	spore germination
KM408_RS13005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM408_RS13015	COG2223	nitrite transmembrane transporter activity
KM408_RS13030	COG2816	NAD+ diphosphatase activity
KM408_RS13035	COG0592	DNA-directed DNA polymerase activity
KM408_RS13040	COG1051	belongs to the nudix hydrolase family
KM408_RS13075	COG3878	Protein conserved in bacteria
KM408_RS13125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM408_RS13140	COG0322	excinuclease ABC activity
KM408_RS13180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM408_RS13205	COG1011	Hydrolase
KM408_RS13225	COG0076	glutamate decarboxylase activity
KM408_RS13240	COG1523	belongs to the glycosyl hydrolase 13 family
KM408_RS13245	COG3227	Zinc metalloprotease (Elastase)
KM408_RS13265	COG0201	protein transport
KM408_RS13275	COG0697	spore germination
KM408_RS13280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS13310	COG4129	membrane
KM408_RS13315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS13330	COG2959	enzyme of heme biosynthesis
KM408_RS13350	COG3483	tryptophan 2,3-dioxygenase activity
KM408_RS13355	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM408_RS13360	COG3844	kynureninase activity
KM408_RS13365	COG1309	transcriptional regulator
KM408_RS13395	COG3284	Transcriptional regulator
KM408_RS13415	COG1349	DNA-binding transcription factor activity
KM408_RS13435	COG1959	2 iron, 2 sulfur cluster binding
KM408_RS13450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM408_RS13455	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM408_RS13460	COG0022	dehydrogenase e1 component
KM408_RS13465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM408_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS13480	COG0456	acetyltransferase
KM408_RS13480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM408_RS13510	COG4176	ABC-type proline glycine betaine transport system permease component
KM408_RS13515	COG0517	IMP dehydrogenase activity
KM408_RS13515	COG4175	Glycine betaine
KM408_RS13540	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM408_RS13545	COG2153	protein acetylation
KM408_RS13550	COG3397	chitin binding
KM408_RS13565	COG2205	protein histidine kinase activity
KM408_RS13590	COG2333	competence protein COMEC
KM408_RS13590	COG0658	competence protein
KM408_RS13640	COG3973	AAA domain
KM408_RS13655	COG2105	PFAM AIG2 family protein
KM408_RS13660	COG0514	ATP-dependent DNA helicase (RecQ)
KM408_RS13680	COG4637	Psort location Cytoplasmic, score
KM408_RS13705	COG3397	chitin binding
KM408_RS13720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM408_RS13725	COG1115	amino acid carrier protein
KM408_RS13730	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS13735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM408_RS13745	COG3938	Belongs to the proline racemase family
KM408_RS13750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM408_RS13790	COG0586	Pfam SNARE associated Golgi protein
KM408_RS13805	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM408_RS13810	COG0519	Catalyzes the synthesis of GMP from XMP
KM408_RS13815	COG4166	transmembrane transport
KM408_RS13825	COG4948	Mandelate Racemase Muconate Lactonizing
KM408_RS13870	COG2936	dipeptidyl-peptidase activity
KM408_RS13875	COG5002	protein histidine kinase activity
KM408_RS13925	COG1307	EDD domain protein, DegV family
KM408_RS13945	COG2814	Major facilitator Superfamily
KM408_RS13955	COG1664	Polymer-forming cytoskeletal
KM408_RS13960	COG0789	Transcriptional regulator
KM408_RS13965	COG4533	DNA binding
KM408_RS13970	COG0477	Major facilitator Superfamily
KM408_RS13970	COG2814	Major facilitator Superfamily
KM408_RS13990	COG2261	transglycosylase associated protein
KM408_RS14005	COG2226	methyltransferase
KM408_RS14040	COG0436	Aminotransferase
KM408_RS14045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM408_RS14050	COG5146	pantothenate kinase activity
KM408_RS14070	COG1131	(ABC) transporter
KM408_RS14115	COG0628	permease
KM408_RS14130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM408_RS14135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM408_RS14140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM408_RS14145	COG1116	anion transmembrane transporter activity
KM408_RS14165	COG2816	NAD+ diphosphatase activity
KM408_RS14185	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM408_RS14210	COG0697	spore germination
KM408_RS14215	COG2318	DinB family
KM408_RS14235	COG4912	Dna alkylation repair
KM408_RS14255	COG0861	Integral membrane protein TerC family
KM408_RS14260	COG1368	sulfuric ester hydrolase activity
KM408_RS14265	COG0488	(ABC) transporter
KM408_RS14280	COG1309	transcriptional regulator
KM408_RS14295	COG0287	Prephenate dehydrogenase
KM408_RS14300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM408_RS14305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM408_RS14310	COG1605	Chorismate mutase
KM408_RS14310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM408_RS14345	COG3584	3D domain protein
KM408_RS14345	COG1388	LysM domain
KM408_RS14355	COG1595	DNA-templated transcription, initiation
KM408_RS14380	COG1879	ABC-type sugar transport system periplasmic component
KM408_RS14390	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM408_RS14400	COG2390	Transcriptional regulator
KM408_RS14435	COG2329	Antibiotic biosynthesis monooxygenase
KM408_RS14455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS14465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM408_RS14470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM408_RS14475	COG4187	Peptidase family M20/M25/M40
KM408_RS14480	COG1414	Transcriptional regulator
KM408_RS14485	COG0833	amino acid
KM408_RS14490	COG1690	Belongs to the RtcB family
KM408_RS14500	COG1785	Belongs to the alkaline phosphatase family
KM408_RS14510	COG3655	Transcriptional regulator
KM408_RS14525	COG4377	Putative membrane peptidase family (DUF2324)
KM408_RS14535	COG3279	Response regulator of the LytR AlgR family
KM408_RS14545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS14550	COG0346	lactoylglutathione lyase activity
KM408_RS14570	COG0714	Associated with various cellular activities
KM408_RS14595	COG0463	Glycosyl transferase, family 2
KM408_RS14615	COG0463	Glycosyl transferase, family 2
KM408_RS14625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM408_RS14630	COG0753	catalase activity
KM408_RS14640	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM408_RS14665	COG0714	Associated with various cellular activities
KM408_RS14675	COG0778	Nitroreductase
KM408_RS14680	COG1846	Transcriptional regulator
KM408_RS14715	COG1725	Transcriptional regulator
KM408_RS14725	COG0577	efflux transmembrane transporter activity
KM408_RS14725	COG1136	(ABC) transporter
KM408_RS14750	COG2207	Transcriptional regulator
KM408_RS14755	COG0456	acetyltransferase
KM408_RS14775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS14795	COG0642	Histidine kinase
KM408_RS14800	COG0745	RESPONSE REGULATOR receiver
KM408_RS14805	COG0596	Alpha beta hydrolase
KM408_RS14835	COG0730	response to heat
KM408_RS14845	COG0833	amino acid
KM408_RS14855	COG4335	DNA alkylation repair
KM408_RS14895	COG0768	penicillin binding
KM408_RS14905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM408_RS14940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM408_RS14945	COG1414	Transcriptional regulator
KM408_RS14960	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM408_RS14965	COG0640	Transcriptional regulator
KM408_RS14975	COG1960	acyl-CoA dehydrogenase activity
KM408_RS14990	COG3314	Sporulation integral membrane protein YlbJ
KM408_RS15005	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM408_RS15020	COG0574	Belongs to the PEP-utilizing enzyme family
KM408_RS15020	COG3848	Pyruvate phosphate dikinase
KM408_RS15025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS15040	COG5577	PFAM Coat F domain
KM408_RS15045	COG3403	YqcI/YcgG family
KM408_RS15050	COG1280	lysine exporter protein (LysE YggA)
KM408_RS15085	COG1063	alcohol dehydrogenase
KM408_RS15100	COG1027	Aspartate ammonia-lyase
KM408_RS15105	COG0252	asparaginase activity
KM408_RS15110	COG1396	sequence-specific DNA binding
KM408_RS15120	COG0322	excinuclease ABC activity
KM408_RS15125	COG0531	amino acid
KM408_RS15130	COG1114	Component of the transport system for branched-chain amino acids
KM408_RS15135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM408_RS15145	COG0281	malic enzyme
KM408_RS15160	COG0531	amino acid
KM408_RS15170	COG0784	Response regulator, receiver
KM408_RS15180	COG2066	Belongs to the glutaminase family
KM408_RS15185	COG1115	amino acid carrier protein
KM408_RS15215	COG0737	Belongs to the 5'-nucleotidase family
KM408_RS15220	COG0753	catalase activity
KM408_RS15225	COG2267	carboxylic ester hydrolase activity
KM408_RS15230	COG1335	isochorismatase
KM408_RS15250	COG0583	DNA-binding transcription factor activity
KM408_RS15300	COG0415	Belongs to the DNA photolyase family
KM408_RS15305	COG0288	reversible hydration of carbon dioxide
KM408_RS15315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM408_RS15320	COG5609	conserved protein (DUF2294)
KM408_RS15335	COG1575	Belongs to the MenA family. Type 1 subfamily
KM408_RS15340	COG2267	carboxylic ester hydrolase activity
KM408_RS15345	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM408_RS15350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM408_RS15355	COG1121	(ABC) transporter
KM408_RS15385	COG0798	PFAM Bile acid sodium symporter
KM408_RS15390	COG0346	lactoylglutathione lyase activity
KM408_RS15395	COG0640	Transcriptional regulator
KM408_RS15410	COG0443	Heat shock 70 kDa protein
KM408_RS15425	COG1522	sequence-specific DNA binding
KM408_RS15440	COG0346	lactoylglutathione lyase activity
KM408_RS15460	COG2169	Transcriptional regulator
KM408_RS15465	COG2169	Transcriptional regulator
KM408_RS15510	COG2814	Major facilitator Superfamily
KM408_RS15535	COG0745	RESPONSE REGULATOR receiver
KM408_RS15540	COG3850	Histidine kinase
KM408_RS15540	COG5002	protein histidine kinase activity
KM408_RS15565	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM408_RS15585	COG1476	TRANSCRIPTIONal
KM408_RS15600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS15605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM408_RS15615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM408_RS15620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM408_RS15635	COG1136	(ABC) transporter
KM408_RS15640	COG0577	efflux transmembrane transporter activity
KM408_RS15655	COG5002	protein histidine kinase activity
KM408_RS15655	COG3850	Histidine kinase
KM408_RS15665	COG2364	Membrane
KM408_RS15670	COG1846	Transcriptional regulator
KM408_RS15680	COG2808	Putative FMN-binding domain
KM408_RS15685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS15690	COG2271	Major facilitator Superfamily
KM408_RS15695	COG1556	Lactate utilization protein
KM408_RS15700	COG1139	Iron-sulfur cluster binding protein
KM408_RS15710	COG0583	DNA-binding transcription factor activity
KM408_RS15720	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM408_RS15745	COG0738	Major facilitator superfamily
KM408_RS15750	COG0673	inositol 2-dehydrogenase activity
KM408_RS15755	COG0561	phosphatase activity
KM408_RS15765	COG1609	Transcriptional regulator
KM408_RS15770	COG0457	Tetratricopeptide repeat
KM408_RS15790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM408_RS15820	COG0534	Mate efflux family protein
KM408_RS15840	COG2814	Major facilitator Superfamily
KM408_RS15845	COG1309	transcriptional regulator
KM408_RS15860	COG0814	amino acid
KM408_RS15865	COG1760	l-serine dehydratase
KM408_RS15870	COG1760	l-serine dehydratase
KM408_RS15880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM408_RS15885	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM408_RS15895	COG1335	isochorismatase
KM408_RS15900	COG1522	sequence-specific DNA binding
KM408_RS15905	COG0531	amino acid
KM408_RS15925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM408_RS15945	COG1595	DNA-templated transcription, initiation
KM408_RS15960	COG0662	Cupin 2, conserved barrel domain protein
KM408_RS15965	COG2207	Transcriptional regulator
KM408_RS15965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM408_RS16015	COG0477	Major facilitator Superfamily
KM408_RS16025	COG1846	Transcriptional regulator
KM408_RS16030	COG2814	Major facilitator Superfamily
KM408_RS16040	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM408_RS16045	COG1131	(ABC) transporter
KM408_RS16065	COG2076	Multidrug Resistance protein
KM408_RS16070	COG1309	transcriptional regulator
KM408_RS16080	COG2031	fatty acid transporter
KM408_RS16090	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM408_RS16120	COG1122	ATPase activity
KM408_RS16125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM408_RS16140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM408_RS16145	COG1288	antiporter activity
KM408_RS16150	COG2356	endonuclease I
KM408_RS16165	COG3620	sequence-specific DNA binding
KM408_RS16170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM408_RS16175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM408_RS16180	COG0124	histidyl-tRNA synthetase
KM408_RS16195	COG1733	regulation of RNA biosynthetic process
KM408_RS16200	COG0778	Nitroreductase
KM408_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS16230	COG1131	(ABC) transporter
KM408_RS16255	COG1011	Hydrolase
KM408_RS16265	COG2365	Tyrosine phosphatase family
KM408_RS16290	COG0346	lactoylglutathione lyase activity
KM408_RS16295	COG1940	carbohydrate kinase activity
KM408_RS16300	COG0738	Major facilitator superfamily
KM408_RS16305	COG0110	maltose O-acetyltransferase activity
KM408_RS16315	COG0577	efflux transmembrane transporter activity
KM408_RS16315	COG1136	(ABC) transporter
KM408_RS16335	COG0628	permease
KM408_RS16355	COG2226	methyltransferase
KM408_RS16365	COG0477	Major facilitator Superfamily
KM408_RS16395	COG1253	flavin adenine dinucleotide binding
KM408_RS16400	COG0789	Transcriptional regulator
KM408_RS16405	COG0697	spore germination
KM408_RS16410	COG1357	PFAM Pentapeptide repeats (8 copies)
KM408_RS16415	COG3813	Protein conserved in bacteria
KM408_RS16420	COG2706	6-phosphogluconolactonase activity
KM408_RS16425	COG1070	Carbohydrate kinase
KM408_RS16435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM408_RS16440	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM408_RS16450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM408_RS16455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM408_RS16460	COG0604	alcohol dehydrogenase
KM408_RS16465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM408_RS16475	COG3321	synthase
KM408_RS16475	COG0604	alcohol dehydrogenase
KM408_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS16505	COG0656	L-ascorbic acid biosynthetic process
KM408_RS16510	COG2814	Major facilitator Superfamily
KM408_RS16525	COG0346	lactoylglutathione lyase activity
KM408_RS16530	COG0814	amino acid
KM408_RS16555	COG1393	Belongs to the ArsC family
KM408_RS16560	COG1733	regulation of RNA biosynthetic process
KM408_RS16565	COG2188	Transcriptional regulator
KM408_RS16575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM408_RS16580	COG1733	regulation of RNA biosynthetic process
KM408_RS16585	COG1733	regulation of RNA biosynthetic process
KM408_RS16600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS16620	COG0384	phenazine biosynthesis protein PhzF
KM408_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS16640	COG0318	PFAM AMP-dependent synthetase and ligase
KM408_RS16650	COG1733	regulation of RNA biosynthetic process
KM408_RS16680	COG1191	sigma factor activity
KM408_RS16695	COG1309	transcriptional regulator
KM408_RS16715	COG3152	Membrane
KM408_RS16740	COG1151	hydroxylamine reductase activity
KM408_RS16750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS16755	COG3757	hydrolase, family 25
KM408_RS16755	COG3409	Peptidoglycan-binding domain 1 protein
KM408_RS16790	COG2072	flavoprotein involved in K transport
KM408_RS16825	COG0604	alcohol dehydrogenase
KM408_RS16830	COG1113	amino acid transport
KM408_RS16835	COG2814	Major facilitator Superfamily
KM408_RS16865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM408_RS16870	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM408_RS16895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS16905	COG3739	integral membrane protein
KM408_RS16910	COG0384	phenazine biosynthesis protein PhzF
KM408_RS16940	COG0583	DNA-binding transcription factor activity
KM408_RS16960	COG1193	negative regulation of DNA recombination
KM408_RS16985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM408_RS17015	COG0584	glycerophosphoryl diester phosphodiesterase
KM408_RS17040	COG0640	Transcriptional regulator
KM408_RS17045	COG0604	alcohol dehydrogenase
KM408_RS17065	COG2808	Putative FMN-binding domain
KM408_RS17070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM408_RS17080	COG0385	Bile acid
KM408_RS17085	COG0277	FAD linked oxidase domain protein
KM408_RS17115	COG1216	Glycosyl transferase, family 2
KM408_RS17120	COG1024	Enoyl-CoA hydratase
KM408_RS17130	COG1285	pathogenesis
KM408_RS17145	COG2514	catechol 2,3-dioxygenase activity
KM408_RS17150	COG2720	vancomycin resistance protein
KM408_RS17190	COG0716	FMN binding
KM408_RS17220	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS17230	COG0165	Argininosuccinate lyase
KM408_RS17245	COG4145	pantothenate transmembrane transporter activity
KM408_RS17255	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS17270	COG1657	PFAM Prenyltransferase squalene oxidase
KM408_RS17275	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM408_RS17280	COG2962	Rard protein
KM408_RS17285	COG3326	Membrane
KM408_RS17300	COG0489	protein tyrosine kinase activity
KM408_RS17310	COG0314	molybdopterin synthase activity
KM408_RS17315	COG0303	'Molybdopterin
KM408_RS17320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM408_RS17325	COG2116	formate transmembrane transporter activity
KM408_RS17335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM408_RS17340	COG5609	conserved protein (DUF2294)
KM408_RS17345	COG2427	Protein of unknown function (DUF1641)
KM408_RS17350	COG3383	formate dehydrogenase (NAD+) activity
KM408_RS17360	COG0697	spore germination
KM408_RS17400	COG2226	methyltransferase
KM408_RS17405	COG4166	transmembrane transport
KM408_RS17410	COG4166	transmembrane transport
KM408_RS17415	COG4166	transmembrane transport
KM408_RS17420	COG1301	dicarboxylic acid transport
KM408_RS17425	COG1316	TRANSCRIPTIONal
KM408_RS17435	COG1595	DNA-templated transcription, initiation
KM408_RS17455	COG1131	(ABC) transporter
KM408_RS17465	COG0673	inositol 2-dehydrogenase activity
KM408_RS17470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM408_RS17475	COG0187	DNA topoisomerase II activity
KM408_RS17480	COG1832	CoA-binding protein
KM408_RS17485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM408_RS17490	COG0745	RESPONSE REGULATOR receiver
KM408_RS17505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM408_RS17510	COG4841	protein insertion into membrane
KM408_RS17515	COG0824	Thioesterase
KM408_RS17545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM408_RS17555	COG2274	protein secretion by the type I secretion system
KM408_RS17560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM408_RS17600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM408_RS17615	COG0183	Belongs to the thiolase family
KM408_RS17620	COG0318	PFAM AMP-dependent synthetase and ligase
KM408_RS17625	COG1268	BioY protein
KM408_RS17630	COG0318	PFAM AMP-dependent synthetase and ligase
KM408_RS17680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS17690	COG5002	protein histidine kinase activity
KM408_RS17695	COG0400	carboxylic ester hydrolase activity
KM408_RS17700	COG0346	lactoylglutathione lyase activity
KM408_RS17705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM408_RS17710	COG0069	glutamate synthase activity
KM408_RS17715	COG1902	pentaerythritol trinitrate reductase activity
KM408_RS17720	COG1329	Transcriptional regulator
KM408_RS17725	COG0010	Belongs to the arginase family
KM408_RS17750	COG2226	methyltransferase
KM408_RS17785	COG4846	Membrane protein involved in cytochrome C biogenesis
KM408_RS17790	COG0785	Cytochrome C biogenesis protein
KM408_RS17800	COG0583	DNA-binding transcription factor activity
KM408_RS17805	COG1380	Effector of murein hydrolase LrgA
KM408_RS17810	COG1346	cytolysis
KM408_RS17835	COG3409	Peptidoglycan-binding domain 1 protein
KM408_RS17835	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM408_RS17850	COG1132	(ABC) transporter
KM408_RS17855	COG1132	(ABC) transporter
KM408_RS17885	COG3639	organic phosphonate transmembrane transporter activity
KM408_RS17890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM408_RS17910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM408_RS17930	COG1695	Transcriptional regulator
KM408_RS17970	COG3409	Peptidoglycan-binding domain 1 protein
KM408_RS17970	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM408_RS17970	COG1388	LysM domain
KM408_RS17975	COG4824	toxin secretion phage lysis holin
KM408_RS18130	COG1595	DNA-templated transcription, initiation
KM408_RS18175	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM408_RS18260	COG1396	sequence-specific DNA binding
KM408_RS18285	COG0174	glutamine synthetase
KM408_RS18290	COG0789	Transcriptional regulator
KM408_RS18295	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM408_RS18305	COG2860	membrane
KM408_RS18310	COG0464	growth
KM408_RS18340	COG3584	3D domain protein
KM408_RS18340	COG1388	LysM domain
KM408_RS18345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM408_RS18345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM408_RS18345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM408_RS18350	COG1105	Belongs to the carbohydrate kinase PfkB family
KM408_RS18355	COG1349	DNA-binding transcription factor activity
KM408_RS18365	COG2322	membrane
KM408_RS18375	COG1113	amino acid transport
KM408_RS18390	COG1408	metallophosphoesterase
KM408_RS18395	COG2116	formate transmembrane transporter activity
KM408_RS18405	COG2217	Heavy metal translocating P-type atpase
KM408_RS18410	COG2608	mercury ion transmembrane transporter activity
KM408_RS18415	COG1937	Protein conserved in bacteria
KM408_RS18425	COG2819	hydrolase of the alpha beta superfamily
KM408_RS18430	COG1120	ATPase activity
KM408_RS18435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS18440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS18450	COG0708	Exodeoxyribonuclease III
KM408_RS18455	COG2169	Transcriptional regulator
KM408_RS18460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM408_RS18465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM408_RS18475	COG2364	Membrane
KM408_RS18490	COG2267	carboxylic ester hydrolase activity
KM408_RS18495	COG0346	lactoylglutathione lyase activity
KM408_RS18500	COG5001	Diguanylate cyclase
KM408_RS18500	COG3300	MHYT domain
KM408_RS18520	COG1346	cytolysis
KM408_RS18525	COG1380	Effector of murein hydrolase LrgA
KM408_RS18530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM408_RS18535	COG0596	Alpha beta hydrolase
KM408_RS18535	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM408_RS18540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM408_RS18560	COG1404	Belongs to the peptidase S8 family
KM408_RS18565	COG3773	Cell wall hydrolase
KM408_RS18570	COG0562	UDP-galactopyranose mutase
KM408_RS18575	COG1368	sulfuric ester hydrolase activity
KM408_RS18580	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM408_RS18590	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM408_RS18615	COG1131	(ABC) transporter
KM408_RS18635	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM408_RS18640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM408_RS18645	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM408_RS18650	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM408_RS18650	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM408_RS18660	COG2359	stage V sporulation protein S
KM408_RS18665	COG1692	metallophosphoesterase
KM408_RS18690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM408_RS18695	COG1426	Protein conserved in bacteria
KM408_RS18710	COG0300	oxidoreductase activity
KM408_RS18715	COG0612	Peptidase, M16
KM408_RS18720	COG0612	Peptidase, M16
KM408_RS18725	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM408_RS18735	COG3845	ABC transporter
KM408_RS18740	COG1744	ABC transporter substrate-binding protein PnrA-like
KM408_RS18745	COG2188	Transcriptional regulator
KM408_RS18750	COG1674	ftsk spoiiie
KM408_RS18760	COG0740	serine-type endopeptidase activity
KM408_RS18765	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM408_RS18775	COG0527	aspartate kinase activity
KM408_RS18780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM408_RS18785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM408_RS18790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM408_RS18795	COG1873	PFAM PRC-barrel domain
KM408_RS18800	COG0612	Peptidase, M16
KM408_RS18805	COG0726	polysaccharide deacetylase
KM408_RS18820	COG0196	riboflavin kinase activity
KM408_RS18825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM408_RS18835	COG1550	Protein conserved in bacteria
KM408_RS18845	COG1358	cellular component organization or biogenesis
KM408_RS18850	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM408_RS18855	COG0195	Participates in both transcription termination and antitermination
KM408_RS18875	COG0750	zinc metalloprotease
KM408_RS18885	COG4589	Belongs to the CDS family
KM408_RS18890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM408_RS18900	COG0528	UMP kinase activity
KM408_RS18930	COG4974	Belongs to the 'phage' integrase family
KM408_RS18940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM408_RS18950	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM408_RS18990	COG1837	Belongs to the UPF0109 family
KM408_RS19000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM408_RS19010	COG0552	protein localization to endoplasmic reticulum
KM408_RS19015	COG1196	nuclear chromosome segregation
KM408_RS19025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM408_RS19030	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS19035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM408_RS19050	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM408_RS19055	COG1461	Dihydroxyacetone kinase
KM408_RS19060	COG1302	Protein conserved in bacteria
KM408_RS19075	COG1564	THIamine pyrophosphokinase
KM408_RS19080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM408_RS19085	COG1162	GTPase activity
KM408_RS19090	COG2815	serine threonine protein kinase
KM408_RS19090	COG0515	serine threonine protein kinase
KM408_RS19095	COG0631	protein serine/threonine phosphatase activity
KM408_RS19105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM408_RS19105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM408_RS19115	COG0242	peptide deformylase activity
KM408_RS19120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM408_RS19125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM408_RS19145	COG1561	YicC-like family, N-terminal region
KM408_RS19150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM408_RS19160	COG0006	proline dipeptidase activity
KM408_RS19175	COG3069	C4-dicarboxylate transmembrane transporter activity
KM408_RS19240	COG0564	pseudouridine synthase activity
KM408_RS19260	COG3599	regulation of cell shape
KM408_RS19265	COG2302	S4 RNA-binding domain
KM408_RS19270	COG0762	integral membrane protein
KM408_RS19280	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM408_RS19285	COG1496	oxidoreductase activity
KM408_RS19290	COG1873	PFAM PRC-barrel domain
KM408_RS19295	COG1191	sigma factor activity
KM408_RS19300	COG1191	sigma factor activity
KM408_RS19310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM408_RS19315	COG0849	cell division
KM408_RS19320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM408_RS19325	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM408_RS19335	COG0772	Belongs to the SEDS family
KM408_RS19350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM408_RS19355	COG0768	penicillin binding
KM408_RS19360	COG0768	penicillin binding
KM408_RS19365	COG4839	cell division protein FtsL
KM408_RS19380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM408_RS19395	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM408_RS19400	COG1399	metal-binding, possibly nucleic acid-binding protein
KM408_RS19450	COG4824	toxin secretion phage lysis holin
KM408_RS19545	COG1802	Transcriptional regulator
KM408_RS19545	COG4626	Terminase
KM408_RS19570	COG0582	viral genome integration into host DNA
KM408_RS19635	COG0756	dUTP diphosphatase activity
KM408_RS19650	COG1191	sigma factor activity
KM408_RS19675	COG1484	DNA-dependent DNA replication
KM408_RS19705	COG1396	sequence-specific DNA binding
KM408_RS19720	COG1396	sequence-specific DNA binding
KM408_RS19735	COG0582	viral genome integration into host DNA
KM408_RS19745	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM408_RS19750	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM408_RS19755	COG3314	Sporulation integral membrane protein YlbJ
KM408_RS19765	COG0742	ribosomal rna small subunit methyltransferase
KM408_RS19780	COG3679	Belongs to the UPF0342 family
KM408_RS19785	COG0406	alpha-ribazole phosphatase activity
KM408_RS19800	COG2340	Cysteine-rich secretory protein family
KM408_RS19815	COG3336	cytochrome c oxidase
KM408_RS19850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM408_RS19855	COG0772	Belongs to the SEDS family
KM408_RS19865	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM408_RS19870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM408_RS19880	COG4896	Protein conserved in bacteria
KM408_RS19895	COG1217	gtp-binding protein TYPA
KM408_RS19905	COG0483	inositol monophosphate 1-phosphatase activity
KM408_RS19925	COG1982	Orn Lys Arg decarboxylase major
KM408_RS19970	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM408_RS19975	COG0022	dehydrogenase e1 component
KM408_RS19980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM408_RS19990	COG0242	peptide deformylase activity
KM408_RS19995	COG0561	phosphatase activity
KM408_RS20005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM408_RS20010	COG0569	domain protein
KM408_RS20030	COG0583	DNA-binding transcription factor activity
KM408_RS20035	COG0517	IMP dehydrogenase activity
KM408_RS20045	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM408_RS20055	COG4703	Protein of unknown function (DUF1797)
KM408_RS20070	COG2200	EAL domain
KM408_RS20075	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS20080	COG1408	metallophosphoesterase
KM408_RS20090	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM408_RS20125	COG2814	Major facilitator Superfamily
KM408_RS20145	COG3209	COG3209 Rhs family protein
KM408_RS20155	COG2205	protein histidine kinase activity
KM408_RS20165	COG0436	Aminotransferase
KM408_RS20170	COG1609	Transcriptional regulator
KM408_RS20175	COG3833	ABC-type maltose transport systems, permease component
KM408_RS20180	COG1175	transmembrane transport
KM408_RS20185	COG2182	Extracellular solute-binding protein
KM408_RS20195	COG0366	Alpha amylase catalytic
KM408_RS20200	COG3842	ATPase activity
KM408_RS20240	COG0183	Belongs to the thiolase family
KM408_RS20275	COG1695	Transcriptional regulator
KM408_RS20280	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS20290	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM408_RS20300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM408_RS20305	COG0436	Aminotransferase
KM408_RS20325	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM408_RS20345	COG2199	diguanylate cyclase activity
KM408_RS20350	COG0778	Nitroreductase
KM408_RS20375	COG1263	PTS System
KM408_RS20375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM408_RS20375	COG2190	(PTS) system
KM408_RS20380	COG3711	transcriptional antiterminator
KM408_RS20390	COG2188	Transcriptional regulator
KM408_RS20400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM408_RS20425	COG1547	Domain of unknown function (DUF309)
KM408_RS20430	COG0456	acetyltransferase
KM408_RS20440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM408_RS20445	COG4086	secreted protein
KM408_RS20450	COG0561	phosphatase activity
KM408_RS20455	COG0697	spore germination
KM408_RS20470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM408_RS20495	COG0733	neurotransmitter:sodium symporter activity
KM408_RS20515	COG1686	Belongs to the peptidase S11 family
KM408_RS20520	COG1725	Transcriptional regulator
KM408_RS20525	COG1131	(ABC) transporter
KM408_RS20540	COG1846	Transcriptional regulator
KM408_RS20555	COG0598	Magnesium transport protein CorA
KM408_RS20580	COG4974	Belongs to the 'phage' integrase family
KM408_RS20590	COG0735	belongs to the Fur family
KM408_RS20595	COG1300	Membrane
KM408_RS20615	COG0667	Aldo Keto reductase
KM408_RS20620	COG0656	L-ascorbic acid biosynthetic process
KM408_RS20625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM408_RS20625	COG0456	acetyltransferase
KM408_RS20635	COG0737	Belongs to the 5'-nucleotidase family
KM408_RS20635	COG1525	nuclease
KM408_RS20635	COG4085	toxin activity
KM408_RS20645	COG0596	Alpha beta hydrolase
KM408_RS20650	COG2056	Na+-H+ antiporter family
KM408_RS20655	COG1609	Transcriptional regulator
KM408_RS20660	COG0456	acetyltransferase
KM408_RS20665	COG1073	alpha beta
KM408_RS20680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM408_RS20680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM408_RS20685	COG0307	riboflavin synthase, alpha
KM408_RS20710	COG4106	trans-aconitate 2-methyltransferase activity
KM408_RS20715	COG1073	alpha beta
KM408_RS20715	COG2226	methyltransferase
KM408_RS20730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM408_RS20740	COG1757	Na H antiporter
KM408_RS20745	COG0737	Belongs to the 5'-nucleotidase family
KM408_RS20755	COG1522	sequence-specific DNA binding
KM408_RS20775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM408_RS20785	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM408_RS20800	COG0300	oxidoreductase activity
KM408_RS20810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM408_RS20815	COG1760	l-serine dehydratase
KM408_RS20820	COG1760	l-serine dehydratase
KM408_RS20840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM408_RS20850	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM408_RS20855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS20870	COG1376	ErfK ybiS ycfS ynhG family protein
KM408_RS20875	COG4129	membrane
KM408_RS20880	COG1126	abc transporter atp-binding protein
KM408_RS20885	COG0765	amino acid transport
KM408_RS20890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM408_RS20905	COG2816	NAD+ diphosphatase activity
KM408_RS20910	COG0772	Belongs to the SEDS family
KM408_RS20915	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM408_RS20920	COG0022	dehydrogenase e1 component
KM408_RS20925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM408_RS20930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM408_RS20945	COG0280	phosphate acetyltransferase
KM408_RS20950	COG3290	protein histidine kinase activity
KM408_RS20950	COG3829	transcription factor binding
KM408_RS20960	COG0584	glycerophosphoryl diester phosphodiesterase
KM408_RS20965	COG3093	addiction module antidote protein HigA
KM408_RS20975	COG0745	RESPONSE REGULATOR receiver
KM408_RS20980	COG0750	zinc metalloprotease
KM408_RS20985	COG0497	DNA recombination
KM408_RS20995	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM408_RS21005	COG0142	geranyltranstransferase activity
KM408_RS21030	COG1302	Protein conserved in bacteria
KM408_RS21035	COG0439	Biotin carboxylase
KM408_RS21040	COG0511	ligase activity, forming carbon-carbon bonds
KM408_RS21085	COG3854	ATPases associated with a variety of cellular activities
KM408_RS21110	COG0006	proline dipeptidase activity
KM408_RS21125	COG3872	metal-dependent enzyme
KM408_RS21135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM408_RS21155	COG0095	Lipoate-protein ligase
KM408_RS21160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM408_RS21165	COG1609	Transcriptional regulator
KM408_RS21175	COG2076	Multidrug Resistance protein
KM408_RS21180	COG2076	Multidrug Resistance protein
KM408_RS21215	COG1131	(ABC) transporter
KM408_RS21220	COG1725	Transcriptional regulator
KM408_RS21250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM408_RS21305	COG4970	Tfp pilus assembly protein FimT
KM408_RS21315	COG1459	type II secretion system
KM408_RS21320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM408_RS21370	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM408_RS21375	COG0646	methionine synthase
KM408_RS21375	COG1410	methionine synthase
KM408_RS21380	COG0646	methionine synthase
KM408_RS21380	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM408_RS21385	COG0626	cystathionine gamma-synthase activity
KM408_RS21390	COG0626	cystathionine gamma-synthase activity
KM408_RS21410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS21420	COG1940	carbohydrate kinase activity
KM408_RS21425	COG4483	Protein conserved in bacteria
KM408_RS21430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM408_RS21435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM408_RS21440	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM408_RS21445	COG0704	Plays a role in the regulation of phosphate uptake
KM408_RS21455	COG0581	inorganic phosphate transmembrane transporter activity
KM408_RS21460	COG0573	inorganic phosphate transmembrane transporter activity
KM408_RS21465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM408_RS21470	COG0768	penicillin binding
KM408_RS21475	COG0477	Major facilitator Superfamily
KM408_RS21480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM408_RS21505	COG0735	belongs to the Fur family
KM408_RS21510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM408_RS21515	COG1121	(ABC) transporter
KM408_RS21520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS21550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM408_RS21555	COG2384	SAM-dependent methyltransferase
KM408_RS21560	COG2010	Cytochrome c
KM408_RS21565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM408_RS21570	COG0358	DNA primase activity
KM408_RS21585	COG0517	IMP dehydrogenase activity
KM408_RS21600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM408_RS21605	COG0295	cytidine deaminase activity
KM408_RS21610	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM408_RS21620	COG1480	7TM receptor with intracellular HD hydrolase
KM408_RS21625	COG1702	phosphate starvation-inducible protein PhoH
KM408_RS21640	COG1610	YqeY-like protein
KM408_RS21645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM408_RS21650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM408_RS21655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM408_RS21685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM408_RS21690	COG1733	regulation of RNA biosynthetic process
KM408_RS21715	COG1466	dna polymerase III delta subunit
KM408_RS21725	COG0658	competence protein
KM408_RS21725	COG2333	competence protein COMEC
KM408_RS21730	COG2131	deaminase
KM408_RS21735	COG1555	photosystem II stabilization
KM408_RS21735	COG1596	polysaccharide export
KM408_RS21740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM408_RS21745	COG2226	methyltransferase
KM408_RS21750	COG0799	negative regulation of ribosome biogenesis
KM408_RS21755	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM408_RS21765	COG1534	Rna-binding protein
KM408_RS21775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM408_RS21780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM408_RS21805	COG1595	DNA-templated transcription, initiation
KM408_RS21815	COG0778	Nitroreductase
KM408_RS21820	COG2357	RelA SpoT domain protein
KM408_RS21830	COG1785	Belongs to the alkaline phosphatase family
KM408_RS21840	COG2267	carboxylic ester hydrolase activity
KM408_RS21875	COG1404	Belongs to the peptidase S8 family
KM408_RS21880	COG3186	Phenylalanine-4-hydroxylase
KM408_RS21895	COG2259	Doxx family
KM408_RS21935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM408_RS21945	COG1012	belongs to the aldehyde dehydrogenase family
KM408_RS21945	COG1454	alcohol dehydrogenase
KM408_RS21950	COG0626	cystathionine gamma-synthase activity
KM408_RS21955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM408_RS21980	COG0768	penicillin binding
KM408_RS21995	COG0826	peptidase U32
KM408_RS22000	COG0826	peptidase U32
KM408_RS22005	COG4122	O-methyltransferase activity
KM408_RS22010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM408_RS22030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM408_RS22040	COG0628	permease
KM408_RS22060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM408_RS22070	COG0482	sulfurtransferase activity
KM408_RS22075	COG1104	cysteine desulfurase activity
KM408_RS22080	COG1959	2 iron, 2 sulfur cluster binding
KM408_RS22085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM408_RS22095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM408_RS22120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM408_RS22130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM408_RS22130	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM408_RS22135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM408_RS22140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM408_RS22140	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM408_RS22150	COG2244	polysaccharide biosynthetic process
KM408_RS22155	COG2323	membrane
KM408_RS22165	COG1862	Preprotein translocase
KM408_RS22195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM408_RS22205	COG0697	spore germination
KM408_RS22210	COG0697	spore germination
KM408_RS22215	COG0640	Transcriptional regulator
KM408_RS22240	COG0157	Belongs to the NadC ModD family
KM408_RS22245	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM408_RS22250	COG1104	cysteine desulfurase activity
KM408_RS22255	COG1827	regulation of RNA biosynthetic process
KM408_RS22260	COG2258	MOSC domain
KM408_RS22265	COG0077	Prephenate dehydratase
KM408_RS22270	COG0577	efflux transmembrane transporter activity
KM408_RS22275	COG0577	efflux transmembrane transporter activity
KM408_RS22280	COG1136	(ABC) transporter
KM408_RS22290	COG0745	RESPONSE REGULATOR receiver
KM408_RS22295	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM408_RS22300	COG3290	protein histidine kinase activity
KM408_RS22310	COG2868	ribosomal protein
KM408_RS22320	COG1530	ribonuclease E activity
KM408_RS22325	COG1994	Peptidase M50
KM408_RS22330	COG0739	heme binding
KM408_RS22335	COG2894	cell division
KM408_RS22355	COG1077	Cell shape determining protein MreB Mrl
KM408_RS22375	COG0285	dihydrofolate synthase activity
KM408_RS22380	COG0525	valine-tRNA ligase activity
KM408_RS22390	COG1388	LysM domain
KM408_RS22400	COG0113	porphobilinogen synthase activity
KM408_RS22405	COG1587	Uroporphyrinogen-III synthase
KM408_RS22415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM408_RS22425	COG1846	Transcriptional regulator
KM408_RS22430	COG1764	response to oxidative stress
KM408_RS22445	COG0470	DNA polymerase III
KM408_RS22445	COG1067	ATP-dependent peptidase activity
KM408_RS22490	COG0622	Phosphoesterase
KM408_RS22505	COG5401	PFAM Sporulation and spore germination
KM408_RS22525	COG1309	transcriptional regulator
KM408_RS22540	COG2197	response regulator
KM408_RS22545	COG2233	PERMEase
KM408_RS22555	COG0402	S-adenosylhomocysteine deaminase activity
KM408_RS22560	COG0402	S-adenosylhomocysteine deaminase activity
KM408_RS22570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM408_RS22580	COG0444	Belongs to the ABC transporter superfamily
KM408_RS22585	COG4608	Belongs to the ABC transporter superfamily
KM408_RS22590	COG3275	phosphorelay sensor kinase activity
KM408_RS22595	COG3279	Response regulator of the LytR AlgR family
KM408_RS22610	COG1983	PspC domain protein
KM408_RS22615	COG1396	sequence-specific DNA binding
KM408_RS22620	COG0697	spore germination
KM408_RS22630	COG1959	2 iron, 2 sulfur cluster binding
KM408_RS22635	COG1668	transmembrane transport
KM408_RS22640	COG4152	abc transporter atp-binding protein
KM408_RS22645	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM408_RS22655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM408_RS22660	COG1876	peptidase activity
KM408_RS22665	COG0824	Thioesterase
KM408_RS22670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM408_RS22675	COG1053	succinate dehydrogenase
KM408_RS22680	COG2009	succinate dehydrogenase
KM408_RS22685	COG1719	4-vinyl reductase, 4VR
KM408_RS22695	COG3118	belongs to the thioredoxin family
KM408_RS22700	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM408_RS22705	COG2086	electron transfer activity
KM408_RS22710	COG1024	Enoyl-CoA hydratase
KM408_RS22720	COG0318	PFAM AMP-dependent synthetase and ligase
KM408_RS22740	COG2318	DinB family
KM408_RS22770	COG1131	(ABC) transporter
KM408_RS22775	COG2205	protein histidine kinase activity
KM408_RS22780	COG0745	RESPONSE REGULATOR receiver
KM408_RS22790	COG4895	conserved protein (DUF2196)
KM408_RS22795	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM408_RS22810	COG4509	Sortase family
KM408_RS22815	COG1120	ATPase activity
KM408_RS22830	COG5386	Cell surface protein
KM408_RS22840	COG5386	Cell surface protein
KM408_RS22845	COG1114	Component of the transport system for branched-chain amino acids
KM408_RS22850	COG1187	pseudouridine synthase activity
KM408_RS22860	COG1796	DNA polymerase
KM408_RS22860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM408_RS22865	COG1286	toxin biosynthetic process
KM408_RS22910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM408_RS22920	COG1418	mRNA catabolic process
KM408_RS22945	COG2814	Major facilitator Superfamily
KM408_RS22950	COG1566	PFAM secretion protein HlyD family protein
KM408_RS22955	COG1309	transcriptional regulator
KM408_RS22960	COG1363	Peptidase, m42
KM408_RS22985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM408_RS22995	COG1484	DNA-dependent DNA replication
KM408_RS23000	COG3611	Membrane attachment protein
KM408_RS23010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM408_RS23015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM408_RS23020	COG0237	dephospho-CoA kinase activity
KM408_RS23025	COG1971	Probably functions as a manganese efflux pump
KM408_RS23035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM408_RS23035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM408_RS23040	COG5002	protein histidine kinase activity
KM408_RS23045	COG0745	RESPONSE REGULATOR receiver
KM408_RS23065	COG0538	isocitrate dehydrogenase activity
KM408_RS23070	COG0372	Belongs to the citrate synthase family
KM408_RS23080	COG0628	permease
KM408_RS23085	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM408_RS23110	COG1725	Transcriptional regulator
KM408_RS23115	COG0281	malic enzyme
KM408_RS23120	COG0587	DNA-directed DNA polymerase activity
KM408_RS23135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM408_RS23155	COG4109	DRTGG domain
KM408_RS23170	COG0006	proline dipeptidase activity
KM408_RS23210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS23215	COG0662	Cupin 2, conserved barrel domain protein
KM408_RS23225	COG1476	TRANSCRIPTIONal
KM408_RS23240	COG1028	Short-chain dehydrogenase reductase Sdr
KM408_RS23245	COG0589	response to stress
KM408_RS23285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS23305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM408_RS23310	COG0827	DNA restriction-modification system
KM408_RS23315	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM408_RS23320	COG3874	Sporulation protein YtfJ
KM408_RS23335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM408_RS23345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM408_RS23360	COG1104	cysteine desulfurase activity
KM408_RS23370	COG0583	DNA-binding transcription factor activity
KM408_RS23375	COG0697	spore germination
KM408_RS23385	COG1956	GAF domain-containing protein
KM408_RS23390	COG0626	cystathionine gamma-synthase activity
KM408_RS23420	COG1595	DNA-templated transcription, initiation
KM408_RS23430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM408_RS23435	COG0454	-acetyltransferase
KM408_RS23440	COG0517	IMP dehydrogenase activity
KM408_RS23445	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM408_RS23455	COG0745	RESPONSE REGULATOR receiver
KM408_RS23465	COG0666	response to abiotic stimulus
KM408_RS23500	COG1609	Transcriptional regulator
KM408_RS23505	COG4851	CamS sex pheromone cAM373 precursor
KM408_RS23510	COG3118	belongs to the thioredoxin family
KM408_RS23520	COG2309	aminopeptidase activity
KM408_RS23540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS23555	COG1674	ftsk spoiiie
KM408_RS23565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM408_RS23570	COG4848	Belongs to the UPF0354 family
KM408_RS23575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM408_RS23580	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM408_RS23585	COG1363	Peptidase, m42
KM408_RS23595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS23610	COG0510	thiamine kinase activity
KM408_RS23615	COG1523	belongs to the glycosyl hydrolase 13 family
KM408_RS23630	COG1349	DNA-binding transcription factor activity
KM408_RS23635	COG1187	pseudouridine synthase activity
KM408_RS23640	COG2244	polysaccharide biosynthetic process
KM408_RS23645	COG2081	HI0933 family
KM408_RS23650	COG2814	Major facilitator Superfamily
KM408_RS23660	COG3832	glyoxalase III activity
KM408_RS23680	COG1329	Transcriptional regulator
KM408_RS23690	COG4975	Glucose uptake
KM408_RS23705	COG0314	molybdopterin synthase activity
KM408_RS23710	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM408_RS23715	COG0303	'Molybdopterin
KM408_RS23725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM408_RS23750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM408_RS23760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM408_RS23805	COG2814	Major facilitator Superfamily
KM408_RS23810	COG0475	glutathione-regulated potassium exporter activity
KM408_RS23815	COG0490	domain, Protein
KM408_RS23820	COG0582	viral genome integration into host DNA
KM408_RS23830	COG1136	(ABC) transporter
KM408_RS23850	COG1242	4 iron, 4 sulfur cluster binding
KM408_RS23855	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM408_RS23860	COG1131	(ABC) transporter
KM408_RS23870	COG1794	racemase activity, acting on amino acids and derivatives
KM408_RS23890	COG2267	carboxylic ester hydrolase activity
KM408_RS23895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM408_RS23900	COG0671	phosphoesterase, PA-phosphatase related
KM408_RS23905	COG0438	transferase activity, transferring glycosyl groups
KM408_RS23915	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM408_RS23970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM408_RS23975	COG5002	protein histidine kinase activity
KM408_RS23980	COG4191	Histidine kinase
KM408_RS23985	COG2267	carboxylic ester hydrolase activity
KM408_RS24005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM408_RS24010	COG1116	anion transmembrane transporter activity
KM408_RS24015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM408_RS24040	COG0494	nUDIX hydrolase
KM408_RS24075	COG0288	reversible hydration of carbon dioxide
KM408_RS24080	COG1271	oxidase subunit
KM408_RS24085	COG1294	oxidase, subunit
KM408_RS24105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS24130	COG1842	Phage shock protein A
KM408_RS24160	COG5002	protein histidine kinase activity
KM408_RS24165	COG0745	RESPONSE REGULATOR receiver
KM408_RS24195	COG1597	lipid kinase activity
KM408_RS24230	COG0586	Pfam SNARE associated Golgi protein
KM408_RS24240	COG0577	efflux transmembrane transporter activity
KM408_RS24245	COG1136	(ABC) transporter
KM408_RS24250	COG3708	Transcriptional regulator
KM408_RS24250	COG2207	Transcriptional regulator
KM408_RS24255	COG0745	RESPONSE REGULATOR receiver
KM408_RS24260	COG2205	protein histidine kinase activity
KM408_RS24270	COG0577	efflux transmembrane transporter activity
KM408_RS24275	COG1136	(ABC) transporter
KM408_RS24295	COG2188	Transcriptional regulator
KM408_RS24315	COG3964	amidohydrolase
KM408_RS24345	COG4948	Mandelate Racemase Muconate Lactonizing
KM408_RS24355	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM408_RS24360	COG0596	Alpha beta hydrolase
KM408_RS24365	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM408_RS24370	COG1169	isochorismate synthase
KM408_RS24375	COG1575	Belongs to the MenA family. Type 1 subfamily
KM408_RS24380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM408_RS24400	COG0058	SHG alpha-glucan phosphorylase activity
KM408_RS24405	COG0297	glycogen (starch) synthase activity
KM408_RS24410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM408_RS24525	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM408_RS24560	COG1285	pathogenesis
KM408_RS24565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM408_RS24575	COG0166	Belongs to the GPI family
KM408_RS24580	COG2155	Conserved Protein
KM408_RS24585	COG1098	S1 RNA binding domain
KM408_RS24590	COG0436	Aminotransferase
KM408_RS24595	COG1522	sequence-specific DNA binding
KM408_RS24600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM408_RS24605	COG2267	carboxylic ester hydrolase activity
KM408_RS24615	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM408_RS24635	COG5018	Exonuclease
KM408_RS24640	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM408_RS24660	COG2050	protein possibly involved in aromatic compounds catabolism
KM408_RS24670	COG1268	BioY protein
KM408_RS24680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM408_RS24685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM408_RS24700	COG3584	3D domain protein
KM408_RS24715	COG1252	NADH dehydrogenase
KM408_RS24730	COG3708	Transcriptional regulator
KM408_RS24745	COG1683	Conserved Protein
KM408_RS24765	COG0316	Belongs to the HesB IscA family
KM408_RS24780	COG1252	NADH dehydrogenase
KM408_RS24795	COG0390	transport system, permease component
KM408_RS24800	COG2824	Alkylphosphonate utilization operon protein PhnA
KM408_RS24840	COG4837	Protein of unknown function (DUF1462)
KM408_RS24845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM408_RS24855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM408_RS24860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM408_RS24870	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM408_RS24875	COG0647	UMP catabolic process
KM408_RS24885	COG2445	Protein of unknown function DUF86
KM408_RS24890	COG1494	fructose-1,6-bisphosphatase
KM408_RS24905	COG4470	Protein conserved in bacteria
KM408_RS24915	COG0789	Transcriptional regulator
KM408_RS24920	COG4377	Putative membrane peptidase family (DUF2324)
KM408_RS24945	COG0739	heme binding
KM408_RS24955	COG3377	Domain of unknown function (DUF1805)
KM408_RS24960	COG0737	Belongs to the 5'-nucleotidase family
KM408_RS24965	COG1695	Transcriptional regulator
KM408_RS24975	COG0719	Fe-S assembly protein
KM408_RS24980	COG0822	iron-sulfur transferase activity
KM408_RS24985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM408_RS24990	COG0719	Fe-S assembly protein
KM408_RS24995	COG0396	ATPase activity
KM408_RS25000	COG1464	Belongs to the NlpA lipoprotein family
KM408_RS25005	COG1464	Belongs to the NlpA lipoprotein family
KM408_RS25010	COG2011	ABC-type metal ion transport system permease component
KM408_RS25015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM408_RS25025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM408_RS25030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM408_RS25040	COG1393	Belongs to the ArsC family
KM408_RS25085	COG0039	L-malate dehydrogenase activity
KM408_RS25110	COG1309	transcriptional regulator
KM408_RS25115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM408_RS25120	COG1960	acyl-CoA dehydrogenase activity
KM408_RS25125	COG0183	Belongs to the thiolase family
KM408_RS25130	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM408_RS25130	COG1024	Enoyl-CoA hydratase
KM408_RS25140	COG1686	Belongs to the peptidase S11 family
KM408_RS25155	COG0011	TIGRFAM Protein of
KM408_RS25160	COG0840	transmembrane signaling receptor activity
KM408_RS25180	COG2814	Major facilitator Superfamily
KM408_RS25185	COG0531	amino acid
KM408_RS25195	COG0706	membrane insertase activity
KM408_RS25205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM408_RS25240	COG0586	Pfam SNARE associated Golgi protein
KM408_RS25250	COG1376	ErfK ybiS ycfS ynhG family protein
KM408_RS25255	COG0745	RESPONSE REGULATOR receiver
KM408_RS25260	COG5002	protein histidine kinase activity
KM408_RS25285	COG2151	metal-sulfur cluster biosynthetic enzyme
KM408_RS25290	COG3227	Zinc metalloprotease (Elastase)
KM408_RS25295	COG1741	Belongs to the pirin family
KM408_RS25310	COG0475	glutathione-regulated potassium exporter activity
KM408_RS25315	COG0490	domain, Protein
KM408_RS25320	COG1115	amino acid carrier protein
KM408_RS25325	COG0783	Belongs to the Dps family
KM408_RS25340	COG1611	Belongs to the LOG family
KM408_RS25360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS25365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS25370	COG1115	amino acid carrier protein
KM408_RS25375	COG1115	amino acid carrier protein
KM408_RS25380	COG2910	NAD(P)H-binding
KM408_RS25395	COG0656	L-ascorbic acid biosynthetic process
KM408_RS25400	COG2814	Major facilitator Superfamily
KM408_RS25405	COG1733	regulation of RNA biosynthetic process
KM408_RS25415	COG1252	NADH dehydrogenase
KM408_RS25420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM408_RS25425	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM408_RS25435	COG3290	protein histidine kinase activity
KM408_RS25435	COG0840	transmembrane signaling receptor activity
KM408_RS25445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM408_RS25450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM408_RS25465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM408_RS25520	COG0557	exoribonuclease II activity
KM408_RS25525	COG1647	Serine aminopeptidase, S33
KM408_RS25530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM408_RS25535	COG1346	cytolysis
KM408_RS25635	COG4695	Portal protein
KM408_RS25660	COG4974	Belongs to the 'phage' integrase family
KM408_RS25670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM408_RS25675	COG0149	triose-phosphate isomerase activity
KM408_RS25685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM408_RS25700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM408_RS25725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM408_RS25740	COG2323	membrane
KM408_RS25745	COG0740	serine-type endopeptidase activity
KM408_RS25750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM408_RS25760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM408_RS25770	COG1051	belongs to the nudix hydrolase family
KM408_RS25780	COG0492	ferredoxin-NADP+ reductase activity
KM408_RS25785	COG0457	Tetratricopeptide repeat
KM408_RS25790	COG0110	maltose O-acetyltransferase activity
KM408_RS25810	COG1950	PFAM Membrane protein of
KM408_RS25820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM408_RS25825	COG0556	nucleotide-excision repair
KM408_RS25845	COG0789	Transcriptional regulator
KM408_RS25870	COG2855	membrane
KM408_RS25875	COG0583	DNA-binding transcription factor activity
KM408_RS25885	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM408_RS25890	COG0488	(ABC) transporter
KM408_RS25900	COG1132	(ABC) transporter
KM408_RS25905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM408_RS25910	COG3409	Peptidoglycan-binding domain 1 protein
KM408_RS25910	COG0793	Belongs to the peptidase S41A family
KM408_RS25915	COG2177	Part of the ABC transporter FtsEX involved in
KM408_RS25920	COG2884	Cell division ATP-binding protein ftsE
KM408_RS25935	COG0653	protein targeting
KM408_RS25940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM408_RS25945	COG1278	Cold shock
KM408_RS25950	COG1040	competence protein
KM408_RS25955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM408_RS25960	COG1388	LysM domain
KM408_RS25960	COG0791	NLP P60 protein
KM408_RS25965	COG1733	regulation of RNA biosynthetic process
KM408_RS25970	COG1307	EDD domain protein, DegV family
KM408_RS25975	COG1739	Uncharacterized protein family UPF0029
KM408_RS25980	COG1316	TRANSCRIPTIONal
KM408_RS25985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM408_RS25990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM408_RS25995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM408_RS26005	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM408_RS26005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM408_RS26020	COG3394	polysaccharide catabolic process
KM408_RS26025	COG1486	melibiose metabolic process
KM408_RS26030	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM408_RS26035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM408_RS26045	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM408_RS26050	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM408_RS26055	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM408_RS26065	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM408_RS26070	COG1301	dicarboxylic acid transport
KM408_RS26080	COG0346	lactoylglutathione lyase activity
KM408_RS26085	COG1511	domain protein
KM408_RS26090	COG0583	DNA-binding transcription factor activity
KM408_RS26095	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM408_RS26110	COG1271	oxidase subunit
KM408_RS26115	COG1294	oxidase, subunit
KM408_RS26120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM408_RS26140	COG2389	metal-binding protein
KM408_RS26150	COG1368	sulfuric ester hydrolase activity
KM408_RS26165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM408_RS26175	COG1215	transferase activity, transferring glycosyl groups
KM408_RS26180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM408_RS26185	COG1388	LysM domain
KM408_RS26185	COG3584	3D domain protein
KM408_RS26210	COG4715	Zinc finger, swim domain protein
KM408_RS26215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM408_RS26255	COG0577	efflux transmembrane transporter activity
KM408_RS26260	COG1136	(ABC) transporter
KM408_RS26295	COG5002	protein histidine kinase activity
KM408_RS26300	COG0745	RESPONSE REGULATOR receiver
KM408_RS26305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM408_RS26325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM408_RS26330	COG1134	teichoic acid transport
KM408_RS26335	COG1682	transport, permease protein
KM408_RS26340	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM408_RS26390	COG1609	Transcriptional regulator
KM408_RS26405	COG0739	heme binding
KM408_RS26425	COG2385	sporulation resulting in formation of a cellular spore
KM408_RS26440	COG4836	Membrane
KM408_RS26445	COG1007	ATP synthesis coupled electron transport
KM408_RS26450	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM408_RS26455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM408_RS26465	COG0839	Belongs to the complex I subunit 6 family
KM408_RS26480	COG0649	NAD binding
KM408_RS26485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM408_RS26500	COG5001	Diguanylate cyclase
KM408_RS26500	COG3300	MHYT domain
KM408_RS26550	COG0356	it plays a direct role in the translocation of protons across the membrane
KM408_RS26585	COG0698	ribose 5-phosphate isomerase
KM408_RS26595	COG2190	(PTS) system
KM408_RS26600	COG2259	Doxx family
KM408_RS26605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM408_RS26620	COG0009	L-threonylcarbamoyladenylate synthase
KM408_RS26635	COG2890	protein-(glutamine-N5) methyltransferase activity
KM408_RS26655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM408_RS26660	COG1494	fructose-1,6-bisphosphatase
KM408_RS26680	COG4821	SIS domain
KM408_RS26690	COG3343	RNA polymerase activity
KM408_RS26700	COG1960	acyl-CoA dehydrogenase activity
KM408_RS26705	COG1960	acyl-CoA dehydrogenase activity
KM408_RS26710	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM408_RS26715	COG0183	Belongs to the thiolase family
KM408_RS26720	COG2181	nitrate reductase activity
KM408_RS26720	COG0247	lactate metabolic process
KM408_RS26725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM408_RS26735	COG3300	MHYT domain
KM408_RS26735	COG5001	Diguanylate cyclase
KM408_RS26755	COG2197	response regulator
KM408_RS26760	COG4585	Histidine kinase
KM408_RS26765	COG0842	Transport permease protein
KM408_RS26770	COG1131	(ABC) transporter
KM408_RS26775	COG0024	Methionine aminopeptidase
KM408_RS26785	COG2234	aminopeptidase activity
KM408_RS26805	COG1595	DNA-templated transcription, initiation
KM408_RS26810	COG0018	arginyl-trna synthetase
KM408_RS26815	COG4506	Protein conserved in bacteria
KM408_RS26820	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM408_RS26835	COG0010	Belongs to the arginase family
KM408_RS26845	COG2814	Major facilitator Superfamily
KM408_RS26850	COG0789	Transcriptional regulator
KM408_RS26855	COG0584	glycerophosphoryl diester phosphodiesterase
KM408_RS26860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM408_RS26870	COG1994	Peptidase M50
KM408_RS26880	COG1078	dGTPase activity
KM408_RS26885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM408_RS26890	COG1120	ATPase activity
KM408_RS26895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM408_RS26920	COG0095	Lipoate-protein ligase
KM408_RS26925	COG0280	phosphate acetyltransferase
KM408_RS26940	COG3773	Cell wall hydrolase
KM408_RS26950	COG2363	Small membrane protein
KM408_RS26960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM408_RS26965	COG2233	PERMEase
KM408_RS26970	COG0561	phosphatase activity
KM408_RS26975	COG2814	Major facilitator Superfamily
KM408_RS26985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM408_RS26990	COG1131	(ABC) transporter
KM408_RS26995	COG2755	lipolytic protein G-D-S-L family
KM408_RS27000	COG1609	Transcriptional regulator
KM408_RS27010	COG0460	homoserine dehydrogenase
KM408_RS27020	COG2873	o-acetylhomoserine
KM408_RS27030	COG1011	Hydrolase
KM408_RS27035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM408_RS27045	COG2197	response regulator
KM408_RS27055	COG0351	phosphomethylpyrimidine kinase
KM408_RS27060	COG3706	GGDEF domain
KM408_RS27065	COG2879	small protein
KM408_RS27070	COG1966	Carbon starvation protein
KM408_RS27075	COG3279	Response regulator of the LytR AlgR family
KM408_RS27080	COG0477	Major facilitator Superfamily
KM408_RS27105	COG0840	transmembrane signaling receptor activity
KM408_RS27115	COG1607	acyl-coa hydrolase
KM408_RS27130	COG0488	(ABC) transporter
KM408_RS27150	COG0463	Glycosyl transferase, family 2
KM408_RS27155	COG1309	transcriptional regulator
KM408_RS27160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM408_RS27165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM408_RS27165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM408_RS27170	COG0628	permease
KM408_RS27185	COG3279	Response regulator of the LytR AlgR family
KM408_RS27190	COG3275	phosphorelay sensor kinase activity
KM408_RS27195	COG2814	Major facilitator Superfamily
KM408_RS27200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM408_RS27205	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM408_RS27210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM408_RS27230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM408_RS27235	COG1272	protein, Hemolysin III
KM408_RS27255	COG0516	GMP reductase activity
KM408_RS27260	COG1164	Oligoendopeptidase f
KM408_RS27280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM408_RS27285	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM408_RS27290	COG4853	Protein conserved in bacteria
KM408_RS27295	COG4863	YycH protein
KM408_RS27300	COG5002	protein histidine kinase activity
KM408_RS27305	COG0745	RESPONSE REGULATOR receiver
KM408_RS27335	COG0305	Participates in initiation and elongation during chromosome replication
KM408_RS27345	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM408_RS27350	COG4241	membrane
KM408_RS27360	COG0629	single-stranded DNA binding
KM408_RS27370	COG0012	GTP binding
KM408_RS27375	COG4481	Protein conserved in bacteria
KM408_RS27380	COG0668	transmembrane transport
KM408_RS27390	COG1475	DNA binding
KM408_RS27395	COG1192	Involved in chromosome partitioning
KM408_RS27420	COG1847	R3H domain protein
KM408_RS27425	COG0706	membrane insertase activity
KM408_RS27435	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM408_RS27490	COG3344	reverse transcriptase
KM408_RS27570	COG3344	reverse transcriptase
KM408_RS27775	COG4962	Type ii secretion system protein e
KM408_RS27910	COG2311	Membrane
KM408_RS27935	COG4196	transglutaminase domain protein
KM408_RS27940	COG0671	phosphoesterase, PA-phosphatase related
KM408_RS27960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM408_RS27965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM408_RS28140	COG2002	toxin-antitoxin pair type II binding
KM408_RS28150	COG4974	Belongs to the 'phage' integrase family
KM408_RS28210	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM408_RS28220	COG4974	Belongs to the 'phage' integrase family
KM408_RS28245	COG0457	Tetratricopeptide repeat
KM408_RS28450	COG0741	lytic transglycosylase activity
KM408_RS28450	COG0791	NLP P60 protein
KM408_RS28570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM408_RS28580	COG4166	transmembrane transport
KM408_RS28625	COG1280	lysine exporter protein (LysE YggA)
KM408_RS28650	COG0681	Belongs to the peptidase S26 family
KM408_RS28725	COG1309	transcriptional regulator
KM408_RS28730	COG1683	Conserved Protein
KM408_RS28780	COG1192	Involved in chromosome partitioning