locus-tag	class	description
KM387_RS00010	COG0592	DNA-directed DNA polymerase activity
KM387_RS00015	COG2501	S4 domain
KM387_RS00025	COG0187	DNA topoisomerase II activity
KM387_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM387_RS00065	COG0516	GMP reductase activity
KM387_RS00065	COG0517	IMP dehydrogenase activity
KM387_RS00070	COG1686	Belongs to the peptidase S11 family
KM387_RS00100	COG1428	Deoxynucleoside kinase
KM387_RS00105	COG1428	Deoxynucleoside kinase
KM387_RS00110	COG1335	isochorismatase
KM387_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM387_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM387_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM387_RS00190	COG0470	DNA polymerase III
KM387_RS00195	COG1774	PSP1 C-terminal conserved region
KM387_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM387_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM387_RS00220	COG2002	toxin-antitoxin pair type II binding
KM387_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_RS00230	COG0084	hydrolase, TatD family'
KM387_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM387_RS00250	COG4466	Protein conserved in bacteria
KM387_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM387_RS00270	COG0251	oxidation-reduction process
KM387_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM387_RS00305	COG2002	toxin-antitoxin pair type II binding
KM387_RS00310	COG2244	polysaccharide biosynthetic process
KM387_RS00315	COG3956	TIGRFAM MazG family protein
KM387_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM387_RS00340	COG1098	S1 RNA binding domain
KM387_RS00355	COG2208	phosphoserine phosphatase activity
KM387_RS00360	COG0037	tRNA processing
KM387_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM387_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM387_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM387_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM387_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM387_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM387_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM387_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM387_RS00420	COG1396	sequence-specific DNA binding
KM387_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM387_RS00455	COG3880	PFAM UvrB UvrC protein
KM387_RS00465	COG0542	response to heat
KM387_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM387_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM387_RS00500	COG1045	serine acetyltransferase
KM387_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM387_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM387_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM387_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM387_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM387_RS00565	COG2813	Specifically methylates the guanine in position
KM387_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM387_RS00580	COG1358	cellular component organization or biogenesis
KM387_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM387_RS00710	COG0201	protein transport
KM387_RS00720	COG0024	Methionine aminopeptidase
KM387_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM387_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM387_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_RS00795	COG0489	protein tyrosine kinase activity
KM387_RS00805	COG2194	sulfuric ester hydrolase activity
KM387_RS00810	COG0726	polysaccharide deacetylase
KM387_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM387_RS00895	COG4856	YbbR-like protein
KM387_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM387_RS00915	COG0596	Alpha beta hydrolase
KM387_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM387_RS00940	COG4946	Tricorn protease homolog
KM387_RS00940	COG1506	peptidase
KM387_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM387_RS00970	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS00975	COG2011	ABC-type metal ion transport system permease component
KM387_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM387_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM387_RS00990	COG0604	alcohol dehydrogenase
KM387_RS01000	COG0277	FAD linked oxidase domain protein
KM387_RS01005	COG2271	Major facilitator Superfamily
KM387_RS01015	COG2814	Major facilitator Superfamily
KM387_RS01030	COG0601	transmembrane transport
KM387_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM387_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM387_RS01050	COG4166	transmembrane transport
KM387_RS01060	COG2207	Transcriptional regulator
KM387_RS01075	COG4166	transmembrane transport
KM387_RS01080	COG4166	transmembrane transport
KM387_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM387_RS01105	COG4149	molybdate abc transporter
KM387_RS01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM387_RS01115	COG1910	domain protein
KM387_RS01130	COG0697	spore germination
KM387_RS01145	COG0204	Acyl-transferase
KM387_RS01155	COG1609	Transcriptional regulator
KM387_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS01175	COG0084	hydrolase, TatD family'
KM387_RS01180	COG5298	Protein conserved in bacteria
KM387_RS01205	COG0488	(ABC) transporter
KM387_RS01220	COG0747	negative chemotaxis
KM387_RS01225	COG0601	transmembrane transport
KM387_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM387_RS01240	COG4608	Belongs to the ABC transporter superfamily
KM387_RS01245	COG0561	phosphatase activity
KM387_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM387_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM387_RS01290	COG2814	Major facilitator Superfamily
KM387_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM387_RS01310	COG4294	response to UV
KM387_RS01315	COG0457	Tetratricopeptide repeat
KM387_RS01315	COG0705	Rhomboid family
KM387_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM387_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM387_RS01335	COG0864	Transcriptional regulator
KM387_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM387_RS01345	COG2183	response to ionizing radiation
KM387_RS01440	COG0802	atpase or kinase
KM387_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
KM387_RS01450	COG0456	acetyltransferase
KM387_RS01460	COG0488	(ABC) transporter
KM387_RS01475	COG1266	CAAX protease self-immunity
KM387_RS01495	COG2252	PERMEase
KM387_RS01505	COG5002	protein histidine kinase activity
KM387_RS01535	COG2226	methyltransferase
KM387_RS01545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_RS01580	COG1968	undecaprenyl-diphosphatase activity
KM387_RS01595	COG2205	protein histidine kinase activity
KM387_RS01600	COG0745	RESPONSE REGULATOR receiver
KM387_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM387_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM387_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM387_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM387_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM387_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM387_RS01680	COG0151	Belongs to the GarS family
KM387_RS01705	COG0210	DNA helicase
KM387_RS01715	COG4851	CamS sex pheromone cAM373 precursor
KM387_RS01735	COG1335	isochorismatase
KM387_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM387_RS01745	COG2011	ABC-type metal ion transport system permease component
KM387_RS01750	COG1464	Belongs to the NlpA lipoprotein family
KM387_RS01765	COG0003	Pfam Anion-transporting ATPase
KM387_RS01770	COG1846	Transcriptional regulator
KM387_RS01775	COG4682	membrane
KM387_RS01795	COG1597	lipid kinase activity
KM387_RS01800	COG0546	phosphoglycolate phosphatase activity
KM387_RS01805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM387_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS01820	COG2076	Multidrug Resistance protein
KM387_RS01825	COG2309	aminopeptidase activity
KM387_RS01840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS01845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM387_RS01850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM387_RS01860	COG4807	Protein conserved in bacteria
KM387_RS01885	COG1757	Na H antiporter
KM387_RS01890	COG1473	amidohydrolase
KM387_RS01905	COG0450	alkyl hydroperoxide reductase
KM387_RS01925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS01935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS01950	COG0166	Belongs to the GPI family
KM387_RS01985	COG5002	protein histidine kinase activity
KM387_RS02005	COG3541	Predicted nucleotidyltransferase
KM387_RS02010	COG2814	Major facilitator Superfamily
KM387_RS02015	COG0723	plastoquinol--plastocyanin reductase activity
KM387_RS02015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_RS02025	COG0765	amino acid transport
KM387_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_RS02040	COG0840	transmembrane signaling receptor activity
KM387_RS02045	COG0840	transmembrane signaling receptor activity
KM387_RS02050	COG0366	Alpha amylase catalytic
KM387_RS02055	COG1263	PTS System
KM387_RS02055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_RS02055	COG2190	(PTS) system
KM387_RS02085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM387_RS02100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_RS02110	COG1116	anion transmembrane transporter activity
KM387_RS02115	COG0488	(ABC) transporter
KM387_RS02160	COG2270	Major facilitator Superfamily
KM387_RS02190	COG2310	stress, protein
KM387_RS02195	COG2310	stress, protein
KM387_RS02200	COG2310	stress, protein
KM387_RS02205	COG0861	Integral membrane protein TerC family
KM387_RS02215	COG3853	Toxic anion resistance protein (TelA)
KM387_RS02230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM387_RS02240	COG1295	ribonuclease BN
KM387_RS02245	COG2217	Heavy metal translocating P-type atpase
KM387_RS02250	COG0697	spore germination
KM387_RS02270	COG0586	Pfam SNARE associated Golgi protein
KM387_RS02285	COG3871	stress protein (general stress protein 26)
KM387_RS02290	COG0387	Pfam Sodium calcium exchanger
KM387_RS02300	COG0535	radical SAM domain protein
KM387_RS02325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM387_RS02330	COG0582	viral genome integration into host DNA
KM387_RS02340	COG1396	sequence-specific DNA binding
KM387_RS02355	COG1396	sequence-specific DNA binding
KM387_RS02390	COG1484	DNA-dependent DNA replication
KM387_RS02490	COG0582	viral genome integration into host DNA
KM387_RS02620	COG0101	tRNA pseudouridine synthase activity
KM387_RS02630	COG3829	transcription factor binding
KM387_RS02640	COG0833	amino acid
KM387_RS02645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM387_RS02675	COG1263	PTS System
KM387_RS02675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_RS02680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_RS02695	COG0463	Glycosyl transferase, family 2
KM387_RS02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_RS02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM387_RS02720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM387_RS02740	COG1228	amidohydrolase
KM387_RS02745	COG1090	epimerase
KM387_RS02775	COG1988	membrane-bound metal-dependent
KM387_RS02780	COG1194	a g-specific adenine glycosylase
KM387_RS02805	COG1132	(ABC) transporter
KM387_RS02810	COG4129	membrane
KM387_RS02815	COG0067	glutamate synthase
KM387_RS02815	COG0069	glutamate synthase activity
KM387_RS02815	COG0070	glutamate synthase
KM387_RS02825	COG4555	ABC transporter
KM387_RS02845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM387_RS02850	COG0735	belongs to the Fur family
KM387_RS02970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM387_RS02980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM387_RS02990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM387_RS03000	COG2766	serine protein kinase
KM387_RS03020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM387_RS03030	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM387_RS03035	COG2268	Band 7 protein
KM387_RS03045	COG3290	protein histidine kinase activity
KM387_RS03050	COG4565	transcriptional regulatory protein
KM387_RS03055	COG2851	Citrate transporter
KM387_RS03075	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM387_RS03080	COG3842	ATPase activity
KM387_RS03085	COG1175	transmembrane transport
KM387_RS03090	COG0395	ABC-type sugar transport system, permease component
KM387_RS03100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM387_RS03105	COG0745	RESPONSE REGULATOR receiver
KM387_RS03110	COG5002	protein histidine kinase activity
KM387_RS03120	COG4990	cell redox homeostasis
KM387_RS03130	COG3290	protein histidine kinase activity
KM387_RS03135	COG4565	transcriptional regulatory protein
KM387_RS03140	COG3493	citrate carrier protein
KM387_RS03145	COG0281	malic enzyme
KM387_RS03160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS03170	COG5002	protein histidine kinase activity
KM387_RS03175	COG0745	RESPONSE REGULATOR receiver
KM387_RS03180	COG0454	-acetyltransferase
KM387_RS03180	COG0456	acetyltransferase
KM387_RS03185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM387_RS03190	COG3383	formate dehydrogenase (NAD+) activity
KM387_RS03195	COG2427	Protein of unknown function (DUF1641)
KM387_RS03210	COG0531	amino acid
KM387_RS03215	COG0640	Transcriptional regulator
KM387_RS03220	COG2217	Heavy metal translocating P-type atpase
KM387_RS03225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM387_RS03240	COG3227	Zinc metalloprotease (Elastase)
KM387_RS03260	COG2720	vancomycin resistance protein
KM387_RS03265	COG1316	TRANSCRIPTIONal
KM387_RS03270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS03275	COG0346	lactoylglutathione lyase activity
KM387_RS03280	COG1253	flavin adenine dinucleotide binding
KM387_RS03285	COG1027	Aspartate ammonia-lyase
KM387_RS03290	COG1620	l-lactate permease
KM387_RS03305	COG3104	oligopeptide transport
KM387_RS03310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS03330	COG2226	methyltransferase
KM387_RS03335	COG0156	8-amino-7-oxononanoate synthase activity
KM387_RS03340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_RS03350	COG4548	von Willebrand factor, type A
KM387_RS03355	COG0714	Associated with various cellular activities
KM387_RS03360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_RS03380	COG0531	amino acid
KM387_RS03385	COG2188	Transcriptional regulator
KM387_RS03390	COG1263	PTS System
KM387_RS03390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_RS03395	COG0366	Alpha amylase catalytic
KM387_RS03410	COG0697	spore germination
KM387_RS03420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM387_RS03425	COG1115	amino acid carrier protein
KM387_RS03430	COG1126	abc transporter atp-binding protein
KM387_RS03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_RS03440	COG0765	amino acid transport
KM387_RS03445	COG0765	amino acid transport
KM387_RS03450	COG0833	amino acid
KM387_RS03475	COG2378	regulation of single-species biofilm formation
KM387_RS03480	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM387_RS03485	COG5002	protein histidine kinase activity
KM387_RS03500	COG0659	secondary active sulfate transmembrane transporter activity
KM387_RS03515	COG0747	negative chemotaxis
KM387_RS03525	COG0601	transmembrane transport
KM387_RS03530	COG4608	Belongs to the ABC transporter superfamily
KM387_RS03540	COG2271	Major facilitator Superfamily
KM387_RS03545	COG1846	Transcriptional regulator
KM387_RS03555	COG1609	Transcriptional regulator
KM387_RS03560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM387_RS03575	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM387_RS03580	COG1879	ABC-type sugar transport system periplasmic component
KM387_RS03605	COG1063	alcohol dehydrogenase
KM387_RS03620	COG3568	Endonuclease Exonuclease Phosphatase
KM387_RS03645	COG1968	undecaprenyl-diphosphatase activity
KM387_RS03650	COG0840	transmembrane signaling receptor activity
KM387_RS03655	COG1388	LysM domain
KM387_RS03655	COG3584	3D domain protein
KM387_RS03660	COG1476	TRANSCRIPTIONal
KM387_RS03675	COG3104	oligopeptide transport
KM387_RS03680	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS03695	COG1113	amino acid transport
KM387_RS03700	COG2252	PERMEase
KM387_RS03725	COG0475	glutathione-regulated potassium exporter activity
KM387_RS03725	COG0569	domain protein
KM387_RS03740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM387_RS03745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM387_RS03750	COG4990	cell redox homeostasis
KM387_RS03765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_RS03770	COG0697	spore germination
KM387_RS03775	COG0531	amino acid
KM387_RS03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM387_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM387_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM387_RS03795	COG1918	ferrous iron import across plasma membrane
KM387_RS03800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM387_RS03805	COG0573	inorganic phosphate transmembrane transporter activity
KM387_RS03810	COG0581	inorganic phosphate transmembrane transporter activity
KM387_RS03820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM387_RS03940	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM387_RS03960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM387_RS03965	COG1116	anion transmembrane transporter activity
KM387_RS03970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_RS03975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM387_RS03980	COG0352	thiamine-phosphate diphosphorylase activity
KM387_RS03985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_RS03990	COG2104	thiamine diphosphate biosynthetic process
KM387_RS04000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_RS04005	COG0351	phosphomethylpyrimidine kinase
KM387_RS04045	COG2205	protein histidine kinase activity
KM387_RS04050	COG2814	Major facilitator Superfamily
KM387_RS04055	COG1846	Transcriptional regulator
KM387_RS04070	COG2252	PERMEase
KM387_RS04075	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS04080	COG1376	ErfK ybiS ycfS ynhG family protein
KM387_RS04090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM387_RS04095	COG1621	beta-fructofuranosidase activity
KM387_RS04100	COG1263	PTS System
KM387_RS04100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_RS04105	COG1609	Transcriptional regulator
KM387_RS04115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_RS04155	COG0778	Nitroreductase
KM387_RS04160	COG2719	SpoVR family
KM387_RS04185	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM387_RS04190	COG1937	Protein conserved in bacteria
KM387_RS04195	COG0425	Belongs to the sulfur carrier protein TusA family
KM387_RS04195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_RS04200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_RS04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM387_RS04220	COG2210	Belongs to the sulfur carrier protein TusA family
KM387_RS04225	COG0730	response to heat
KM387_RS04235	COG1316	TRANSCRIPTIONal
KM387_RS04240	COG0604	alcohol dehydrogenase
KM387_RS04245	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM387_RS04260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM387_RS04260	COG3711	transcriptional antiterminator
KM387_RS04265	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM387_RS04270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM387_RS04290	COG3584	3D domain protein
KM387_RS04290	COG1388	LysM domain
KM387_RS04295	COG0577	efflux transmembrane transporter activity
KM387_RS04300	COG1136	(ABC) transporter
KM387_RS04310	COG5522	Integral membrane protein (intg_mem_TP0381)
KM387_RS04325	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS04330	COG3546	catalase activity
KM387_RS04365	COG0586	Pfam SNARE associated Golgi protein
KM387_RS04405	COG0531	amino acid
KM387_RS04410	COG0475	glutathione-regulated potassium exporter activity
KM387_RS04420	COG1737	Transcriptional regulator
KM387_RS04430	COG1263	PTS System
KM387_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_RS04440	COG2259	Doxx family
KM387_RS04455	COG0697	spore germination
KM387_RS04460	COG1522	sequence-specific DNA binding
KM387_RS04475	COG2076	Multidrug Resistance protein
KM387_RS04480	COG1309	transcriptional regulator
KM387_RS04485	COG2814	Major facilitator Superfamily
KM387_RS04490	COG1733	regulation of RNA biosynthetic process
KM387_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM387_RS04505	COG4533	DNA binding
KM387_RS04510	COG2211	Major facilitator Superfamily
KM387_RS04520	COG0693	protein deglycase activity
KM387_RS04525	COG0693	protein deglycase activity
KM387_RS04525	COG0753	catalase activity
KM387_RS04535	COG0531	amino acid
KM387_RS04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM387_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS04555	COG1132	(ABC) transporter
KM387_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_RS04570	COG0765	amino acid transport
KM387_RS04575	COG1126	abc transporter atp-binding protein
KM387_RS04590	COG0189	ligase activity
KM387_RS04620	COG0028	Belongs to the TPP enzyme family
KM387_RS04625	COG3527	Alpha-acetolactate decarboxylase
KM387_RS04640	COG0561	phosphatase activity
KM387_RS04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM387_RS04670	COG0659	secondary active sulfate transmembrane transporter activity
KM387_RS04690	COG0653	protein targeting
KM387_RS04695	COG2244	polysaccharide biosynthetic process
KM387_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_RS04710	COG4196	transglutaminase domain protein
KM387_RS04725	COG1696	Membrane protein involved in D-alanine export
KM387_RS04740	COG1024	Enoyl-CoA hydratase
KM387_RS04760	COG1363	Peptidase, m42
KM387_RS04780	COG3938	Belongs to the proline racemase family
KM387_RS04820	COG0601	transmembrane transport
KM387_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_RS04835	COG4608	Belongs to the ABC transporter superfamily
KM387_RS04870	COG0477	Major facilitator Superfamily
KM387_RS04875	COG3290	protein histidine kinase activity
KM387_RS04880	COG4565	transcriptional regulatory protein
KM387_RS04885	COG3181	Tripartite tricarboxylate transporter family receptor
KM387_RS04915	COG0789	Transcriptional regulator
KM387_RS04915	COG4978	Transcriptional regulator
KM387_RS04930	COG0305	Participates in initiation and elongation during chromosome replication
KM387_RS04970	COG0477	Major facilitator Superfamily
KM387_RS05015	COG3320	Male sterility
KM387_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM387_RS05020	COG1309	transcriptional regulator
KM387_RS05040	COG1183	phosphatidylcholine synthase activity
KM387_RS05060	COG2376	Dihydroxyacetone kinase
KM387_RS05070	COG2376	Dihydroxyacetone kinase
KM387_RS05075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM387_RS05080	COG1959	2 iron, 2 sulfur cluster binding
KM387_RS05110	COG3437	response regulator, receiver
KM387_RS05110	COG2770	Histidine kinase
KM387_RS05160	COG3237	CsbD-like
KM387_RS05185	COG1191	sigma factor activity
KM387_RS05195	COG2208	phosphoserine phosphatase activity
KM387_RS05200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM387_RS05205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_RS05205	COG0784	Response regulator, receiver
KM387_RS05205	COG2198	Histidine kinase
KM387_RS05205	COG2205	protein histidine kinase activity
KM387_RS05260	COG0420	3'-5' exonuclease activity
KM387_RS05285	COG1309	transcriptional regulator
KM387_RS05290	COG2814	Major facilitator Superfamily
KM387_RS05295	COG0346	lactoylglutathione lyase activity
KM387_RS05300	COG0346	lactoylglutathione lyase activity
KM387_RS05305	COG0457	Tetratricopeptide repeat
KM387_RS05310	COG2267	carboxylic ester hydrolase activity
KM387_RS05335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM387_RS05345	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM387_RS05385	COG0477	Major facilitator Superfamily
KM387_RS05390	COG0477	Major facilitator Superfamily
KM387_RS05400	COG3973	AAA domain
KM387_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM387_RS05425	COG4980	gas vesicle protein
KM387_RS05430	COG0537	adenosine 5'-monophosphoramidase activity
KM387_RS05435	COG1131	(ABC) transporter
KM387_RS05440	COG4473	ABC transporter
KM387_RS05455	COG1309	transcriptional regulator
KM387_RS05465	COG3402	PFAM membrane-flanked domain
KM387_RS05470	COG3428	Bacterial PH domain
KM387_RS05510	COG3402	PFAM membrane-flanked domain
KM387_RS05520	COG2329	Antibiotic biosynthesis monooxygenase
KM387_RS05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_RS05530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM387_RS05535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM387_RS05540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM387_RS05575	COG1309	transcriptional regulator
KM387_RS05580	COG1511	domain protein
KM387_RS05605	COG1609	Transcriptional regulator
KM387_RS05615	COG1234	tRNA 3'-trailer cleavage
KM387_RS05620	COG0095	Lipoate-protein ligase
KM387_RS05630	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_RS05660	COG3209	COG3209 Rhs family protein
KM387_RS05695	COG1408	metallophosphoesterase
KM387_RS05700	COG1078	dGTPase activity
KM387_RS05710	COG1595	DNA-templated transcription, initiation
KM387_RS05715	COG2207	Transcriptional regulator
KM387_RS05715	COG3708	Transcriptional regulator
KM387_RS05730	COG2205	protein histidine kinase activity
KM387_RS05735	COG0745	RESPONSE REGULATOR receiver
KM387_RS05760	COG0501	Belongs to the peptidase M48B family
KM387_RS05765	COG0840	transmembrane signaling receptor activity
KM387_RS05770	COG0697	spore germination
KM387_RS05790	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM387_RS05795	COG2224	Isocitrate lyase
KM387_RS05820	COG4903	ComK protein
KM387_RS05825	COG0398	Pfam SNARE associated Golgi protein
KM387_RS05835	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM387_RS05840	COG1074	ATP-dependent DNA helicase activity
KM387_RS05885	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM387_RS05910	COG0367	asparagine synthase
KM387_RS05915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM387_RS05920	COG0753	catalase activity
KM387_RS05925	COG0004	ammonium transporteR
KM387_RS05945	COG2996	Protein conserved in bacteria
KM387_RS05955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM387_RS05965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS05980	COG0561	phosphatase activity
KM387_RS05990	COG0542	response to heat
KM387_RS06000	COG2267	carboxylic ester hydrolase activity
KM387_RS06015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_RS06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM387_RS06025	COG5504	Zn-dependent protease
KM387_RS06035	COG0180	Tryptophanyl-tRNA synthetase
KM387_RS06045	COG4166	transmembrane transport
KM387_RS06050	COG0601	transmembrane transport
KM387_RS06055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_RS06060	COG0444	Belongs to the ABC transporter superfamily
KM387_RS06065	COG4608	Belongs to the ABC transporter superfamily
KM387_RS06070	COG0534	Mate efflux family protein
KM387_RS06075	COG4166	transmembrane transport
KM387_RS06090	COG0861	Integral membrane protein TerC family
KM387_RS06095	COG4862	establishment of competence for transformation
KM387_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_RS06120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM387_RS06125	COG2346	COG2346, Truncated hemoglobins
KM387_RS06130	COG4116	CYTH
KM387_RS06140	COG2357	RelA SpoT domain protein
KM387_RS06150	COG0564	pseudouridine synthase activity
KM387_RS06165	COG0772	Belongs to the SEDS family
KM387_RS06170	COG1216	Glycosyl transferase, family 2
KM387_RS06170	COG0463	Glycosyl transferase, family 2
KM387_RS06210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM387_RS06225	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM387_RS06270	COG2153	protein acetylation
KM387_RS06280	COG2382	esterase
KM387_RS06295	COG5492	domain, Protein
KM387_RS06300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_RS06345	COG1620	l-lactate permease
KM387_RS06350	COG5634	Uncharacterized conserved protein (DUF2278)
KM387_RS06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_RS06415	COG1476	TRANSCRIPTIONal
KM387_RS06475	COG2226	methyltransferase
KM387_RS06485	COG1686	Belongs to the peptidase S11 family
KM387_RS06490	COG0681	Belongs to the peptidase S26 family
KM387_RS06525	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS06530	COG3842	ATPase activity
KM387_RS06535	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM387_RS06540	COG1177	transmembrane transport
KM387_RS06545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM387_RS06555	COG2409	Drug exporters of the RND superfamily
KM387_RS06565	COG0564	pseudouridine synthase activity
KM387_RS06575	COG2340	Cysteine-rich secretory protein family
KM387_RS06580	COG0247	lactate metabolic process
KM387_RS06585	COG0277	FAD linked oxidase domain protein
KM387_RS06590	COG3835	regulator
KM387_RS06600	COG0745	RESPONSE REGULATOR receiver
KM387_RS06605	COG5002	protein histidine kinase activity
KM387_RS06610	COG2186	Transcriptional regulator
KM387_RS06630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM387_RS06640	COG2116	formate transmembrane transporter activity
KM387_RS06645	COG0861	Integral membrane protein TerC family
KM387_RS06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM387_RS06660	COG2030	dehydratase
KM387_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS06685	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM387_RS06690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_RS06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM387_RS06710	COG1840	ABC-type Fe3 transport system, periplasmic component
KM387_RS06740	COG1349	DNA-binding transcription factor activity
KM387_RS06760	COG2861	carbohydrate metabolic process
KM387_RS06770	COG3852	Histidine kinase
KM387_RS06775	COG1846	Transcriptional regulator
KM387_RS06785	COG2318	DinB family
KM387_RS06805	COG0720	synthase
KM387_RS06820	COG4873	Protein conserved in bacteria
KM387_RS06850	COG1780	Probably involved in ribonucleotide reductase function
KM387_RS06870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM387_RS06875	COG1725	Transcriptional regulator
KM387_RS06880	COG1131	(ABC) transporter
KM387_RS06890	COG1131	(ABC) transporter
KM387_RS06895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM387_RS06910	COG1522	sequence-specific DNA binding
KM387_RS06920	COG1335	isochorismatase
KM387_RS06930	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM387_RS06935	COG2070	2-Nitropropane dioxygenase
KM387_RS06940	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM387_RS06950	COG1696	Membrane protein involved in D-alanine export
KM387_RS06975	COG0716	FMN binding
KM387_RS06990	COG3173	Aminoglycoside phosphotransferase
KM387_RS07010	COG0534	Mate efflux family protein
KM387_RS07015	COG1968	undecaprenyl-diphosphatase activity
KM387_RS07030	COG1846	Transcriptional regulator
KM387_RS07040	COG1301	dicarboxylic acid transport
KM387_RS07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM387_RS07050	COG4709	membrane
KM387_RS07055	COG3874	Sporulation protein YtfJ
KM387_RS07075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_RS07080	COG0028	Belongs to the TPP enzyme family
KM387_RS07085	COG0440	acetolactate synthase activity
KM387_RS07090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM387_RS07100	COG0473	3-isopropylmalate dehydrogenase activity
KM387_RS07125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM387_RS07160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM387_RS07175	COG1183	phosphatidylcholine synthase activity
KM387_RS07180	COG1368	sulfuric ester hydrolase activity
KM387_RS07190	COG0019	diaminopimelate decarboxylase activity
KM387_RS07210	COG0529	Catalyzes the synthesis of activated sulfate
KM387_RS07215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM387_RS07235	COG1648	precorrin-2 dehydrogenase activity
KM387_RS07240	COG0733	neurotransmitter:sodium symporter activity
KM387_RS07260	COG1757	Na H antiporter
KM387_RS07275	COG4758	membrane
KM387_RS07280	COG4585	Histidine kinase
KM387_RS07285	COG2197	response regulator
KM387_RS07295	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS07305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM387_RS07330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM387_RS07330	COG1017	nitric oxide dioxygenase activity
KM387_RS07345	COG0730	response to heat
KM387_RS07350	COG0306	phosphate transporter
KM387_RS07355	COG1392	Phosphate transport regulator
KM387_RS07360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_RS07375	COG3852	Histidine kinase
KM387_RS07380	COG1801	Protein of unknown function DUF72
KM387_RS07390	COG0582	viral genome integration into host DNA
KM387_RS07395	COG5002	protein histidine kinase activity
KM387_RS07415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM387_RS07415	COG0392	lysyltransferase activity
KM387_RS07430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM387_RS07435	COG1686	Belongs to the peptidase S11 family
KM387_RS07440	COG2715	membrane protein required for spore maturation
KM387_RS07445	COG0700	Nucleoside recognition
KM387_RS07450	COG1187	pseudouridine synthase activity
KM387_RS07460	COG1333	cytochrome c biogenesis protein
KM387_RS07465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM387_RS07470	COG0745	RESPONSE REGULATOR receiver
KM387_RS07475	COG5002	protein histidine kinase activity
KM387_RS07480	COG2096	Adenosyltransferase
KM387_RS07495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM387_RS07500	COG1141	Ferredoxin
KM387_RS07510	COG0514	ATP-dependent DNA helicase (RecQ)
KM387_RS07515	COG1266	CAAX protease self-immunity
KM387_RS07525	COG1408	metallophosphoesterase
KM387_RS07535	COG4862	establishment of competence for transformation
KM387_RS07540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM387_RS07560	COG0492	ferredoxin-NADP+ reductase activity
KM387_RS07565	COG0252	asparaginase activity
KM387_RS07635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM387_RS07650	COG0142	geranyltranstransferase activity
KM387_RS07660	COG0142	geranyltranstransferase activity
KM387_RS07680	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM387_RS07685	COG0457	Tetratricopeptide repeat
KM387_RS07705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM387_RS07715	COG4347	Protein of unknown function (DUF1405)
KM387_RS07730	COG2738	Putative neutral zinc metallopeptidase
KM387_RS07740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS07745	COG1694	Mazg nucleotide pyrophosphohydrolase
KM387_RS07760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM387_RS07765	COG0438	transferase activity, transferring glycosyl groups
KM387_RS07800	COG1199	ATP-dependent helicase activity
KM387_RS07800	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM387_RS07820	COG3935	DnaD domain protein
KM387_RS07825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM387_RS07835	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM387_RS07835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_RS07895	COG0116	Belongs to the methyltransferase superfamily
KM387_RS07905	COG1199	ATP-dependent helicase activity
KM387_RS07910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM387_RS07920	COG3173	Aminoglycoside phosphotransferase
KM387_RS07925	COG0024	Methionine aminopeptidase
KM387_RS07935	COG2233	PERMEase
KM387_RS07940	COG2311	Membrane
KM387_RS07945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM387_RS07955	COG0456	acetyltransferase
KM387_RS07990	COG0754	glutathionylspermidine amidase activity
KM387_RS08005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM387_RS08025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM387_RS08040	COG1215	transferase activity, transferring glycosyl groups
KM387_RS08045	COG0438	transferase activity, transferring glycosyl groups
KM387_RS08065	COG3800	Transcriptional regulator
KM387_RS08065	COG1396	sequence-specific DNA binding
KM387_RS08130	COG0662	Cupin 2, conserved barrel domain protein
KM387_RS08210	COG4626	Terminase
KM387_RS08210	COG1802	Transcriptional regulator
KM387_RS08275	COG4824	toxin secretion phage lysis holin
KM387_RS08340	COG0454	-acetyltransferase
KM387_RS08360	COG0328	RNA-DNA hybrid ribonuclease activity
KM387_RS08400	COG1280	lysine exporter protein (LysE YggA)
KM387_RS08415	COG3162	membrane
KM387_RS08420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_RS08425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM387_RS08435	COG0475	glutathione-regulated potassium exporter activity
KM387_RS08440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM387_RS08445	COG4978	Transcriptional regulator
KM387_RS08445	COG0789	Transcriptional regulator
KM387_RS08455	COG2323	membrane
KM387_RS08460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM387_RS08515	COG1923	regulation of RNA biosynthetic process
KM387_RS08525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM387_RS08530	COG1360	Flagellar Motor Protein
KM387_RS08535	COG2201	protein-glutamate methylesterase activity
KM387_RS08540	COG0643	Histidine kinase
KM387_RS08540	COG2198	Histidine kinase
KM387_RS08545	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_RS08545	COG1776	CheC inhibitor of MCP methylation
KM387_RS08560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM387_RS08580	COG1256	bacterial-type flagellum assembly
KM387_RS08585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM387_RS08605	COG1815	bacterial-type flagellum-dependent cell motility
KM387_RS08610	COG1558	bacterial-type flagellum-dependent cell motility
KM387_RS08620	COG1766	The M ring may be actively involved in energy transduction
KM387_RS08625	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_RS08635	COG1157	protein secretion by the type III secretion system
KM387_RS08670	COG0784	Response regulator, receiver
KM387_RS08670	COG0835	chemotaxis
KM387_RS08680	COG0463	Glycosyl transferase, family 2
KM387_RS08705	COG0457	Tetratricopeptide repeat
KM387_RS08705	COG0463	Glycosyl transferase, family 2
KM387_RS08720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM387_RS08735	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_RS08740	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM387_RS08740	COG1776	CheC inhibitor of MCP methylation
KM387_RS08750	COG1338	Plays a role in the flagellum-specific transport system
KM387_RS08755	COG1987	bacterial-type flagellum assembly
KM387_RS08765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM387_RS08770	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM387_RS08775	COG1419	protein localization to endoplasmic reticulum
KM387_RS08780	COG4786	Flagellar basal body rod
KM387_RS08785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM387_RS08810	COG1309	transcriptional regulator
KM387_RS08830	COG2329	Antibiotic biosynthesis monooxygenase
KM387_RS08855	COG0583	DNA-binding transcription factor activity
KM387_RS08860	COG3842	ATPase activity
KM387_RS08865	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM387_RS08875	COG1234	tRNA 3'-trailer cleavage
KM387_RS08900	COG1686	Belongs to the peptidase S11 family
KM387_RS08910	COG0406	alpha-ribazole phosphatase activity
KM387_RS08930	COG1846	Transcriptional regulator
KM387_RS08940	COG0367	asparagine synthase
KM387_RS08970	COG1802	Transcriptional regulator
KM387_RS08975	COG0697	spore germination
KM387_RS08980	COG0523	cobalamin synthesis protein
KM387_RS08985	COG0701	Predicted permease
KM387_RS08995	COG0438	transferase activity, transferring glycosyl groups
KM387_RS08995	COG1216	Glycosyl transferase, family 2
KM387_RS09000	COG1757	Na H antiporter
KM387_RS09005	COG0114	fumarate hydratase activity
KM387_RS09025	COG0534	Mate efflux family protein
KM387_RS09030	COG3340	Belongs to the peptidase S51 family
KM387_RS09050	COG0785	Cytochrome C biogenesis protein
KM387_RS09080	COG2733	membrane
KM387_RS09110	COG1131	(ABC) transporter
KM387_RS09125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_RS09130	COG0528	UMP kinase activity
KM387_RS09140	COG1027	Aspartate ammonia-lyase
KM387_RS09145	COG0281	malic enzyme
KM387_RS09150	COG4191	Histidine kinase
KM387_RS09155	COG0784	Response regulator, receiver
KM387_RS09160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM387_RS09220	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_RS09230	COG2814	Major facilitator Superfamily
KM387_RS09245	COG1966	Carbon starvation protein
KM387_RS09255	COG0477	Major facilitator Superfamily
KM387_RS09260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_RS09270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM387_RS09275	COG4166	transmembrane transport
KM387_RS09280	COG2223	nitrite transmembrane transporter activity
KM387_RS09285	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM387_RS09300	COG2244	polysaccharide biosynthetic process
KM387_RS09305	COG0733	neurotransmitter:sodium symporter activity
KM387_RS09315	COG5566	PFAM Mor transcription activator
KM387_RS09320	COG2323	membrane
KM387_RS09340	COG2084	Dehydrogenase
KM387_RS09355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM387_RS09365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_RS09370	COG0028	Belongs to the TPP enzyme family
KM387_RS09375	COG0440	acetolactate synthase activity
KM387_RS09380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM387_RS09390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM387_RS09415	COG2814	Major facilitator Superfamily
KM387_RS09430	COG3279	Response regulator of the LytR AlgR family
KM387_RS09435	COG0427	acetyl-CoA hydrolase
KM387_RS09455	COG1073	alpha beta
KM387_RS09460	COG4166	transmembrane transport
KM387_RS09485	COG0535	radical SAM domain protein
KM387_RS09490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS09510	COG1914	H( )-stimulated, divalent metal cation uptake system
KM387_RS09525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM387_RS09555	COG2390	Transcriptional regulator
KM387_RS09565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS09570	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM387_RS09605	COG0006	proline dipeptidase activity
KM387_RS09610	COG2132	Multicopper oxidase
KM387_RS09625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM387_RS09640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM387_RS09645	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS09655	COG2372	response to copper ion
KM387_RS09655	COG1276	copper resistance
KM387_RS09660	COG4549	nuclear export factor GLE1
KM387_RS09670	COG0697	spore germination
KM387_RS09675	COG0583	DNA-binding transcription factor activity
KM387_RS09680	COG1959	2 iron, 2 sulfur cluster binding
KM387_RS09685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM387_RS09700	COG0628	permease
KM387_RS09710	COG1231	oxidoreductase activity
KM387_RS09715	COG0523	cobalamin synthesis protein
KM387_RS09730	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_RS09735	COG2030	dehydratase
KM387_RS09740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_RS09750	COG0411	ABC transporter
KM387_RS09770	COG0583	DNA-binding transcription factor activity
KM387_RS09780	COG1942	4-Oxalocrotonate Tautomerase
KM387_RS09790	COG1846	Transcriptional regulator
KM387_RS09800	COG1271	oxidase subunit
KM387_RS09805	COG1294	oxidase, subunit
KM387_RS09810	COG4988	ABC transporter
KM387_RS09815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM387_RS09835	COG1686	Belongs to the peptidase S11 family
KM387_RS09850	COG0791	NLP P60 protein
KM387_RS09850	COG1388	LysM domain
KM387_RS09860	COG1132	(ABC) transporter
KM387_RS09865	COG0745	RESPONSE REGULATOR receiver
KM387_RS09870	COG5002	protein histidine kinase activity
KM387_RS09880	COG0300	oxidoreductase activity
KM387_RS09915	COG0460	homoserine dehydrogenase
KM387_RS09940	COG1316	TRANSCRIPTIONal
KM387_RS09950	COG0745	RESPONSE REGULATOR receiver
KM387_RS09955	COG5002	protein histidine kinase activity
KM387_RS09970	COG1285	pathogenesis
KM387_RS09975	COG1247	-acetyltransferase
KM387_RS09995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM387_RS10005	COG1082	Xylose isomerase domain protein TIM barrel
KM387_RS10015	COG2814	Major facilitator Superfamily
KM387_RS10020	COG1279	arginine transmembrane transporter activity
KM387_RS10030	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM387_RS10065	COG0577	efflux transmembrane transporter activity
KM387_RS10070	COG2002	toxin-antitoxin pair type II binding
KM387_RS10075	COG1404	Belongs to the peptidase S8 family
KM387_RS10080	COG0640	Transcriptional regulator
KM387_RS10085	COG0667	Aldo Keto reductase
KM387_RS10090	COG2814	Major facilitator Superfamily
KM387_RS10115	COG0840	transmembrane signaling receptor activity
KM387_RS10130	COG3949	Membrane
KM387_RS10135	COG0783	Belongs to the Dps family
KM387_RS10150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM387_RS10160	COG1231	oxidoreductase activity
KM387_RS10170	COG4989	oxidoreductase activity
KM387_RS10175	COG0523	cobalamin synthesis protein
KM387_RS10180	COG0456	acetyltransferase
KM387_RS10240	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM387_RS10240	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM387_RS10250	COG0702	epimerase
KM387_RS10260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM387_RS10270	COG4166	transmembrane transport
KM387_RS10285	COG0406	alpha-ribazole phosphatase activity
KM387_RS10295	COG5337	Spore coat protein CotH
KM387_RS10300	COG1051	belongs to the nudix hydrolase family
KM387_RS10305	COG0586	Pfam SNARE associated Golgi protein
KM387_RS10310	COG2244	polysaccharide biosynthetic process
KM387_RS10320	COG0701	Predicted permease
KM387_RS10325	COG3689	TIGRFAM TIGR03943 family protein
KM387_RS10330	COG1607	acyl-coa hydrolase
KM387_RS10340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_RS10355	COG0702	epimerase
KM387_RS10360	COG2839	Protein conserved in bacteria
KM387_RS10365	COG1253	flavin adenine dinucleotide binding
KM387_RS10380	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS10385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_RS10405	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_RS10415	COG1876	peptidase activity
KM387_RS10425	COG0154	amidase activity
KM387_RS10430	COG2211	Major facilitator Superfamily
KM387_RS10450	COG0561	phosphatase activity
KM387_RS10460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM387_RS10465	COG4106	trans-aconitate 2-methyltransferase activity
KM387_RS10480	COG1819	glycosyl
KM387_RS10485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS10490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS10525	COG0456	acetyltransferase
KM387_RS10580	COG3874	Sporulation protein YtfJ
KM387_RS10605	COG2226	methyltransferase
KM387_RS10630	COG0346	lactoylglutathione lyase activity
KM387_RS10640	COG0604	alcohol dehydrogenase
KM387_RS10645	COG1595	DNA-templated transcription, initiation
KM387_RS10670	COG0386	Belongs to the glutathione peroxidase family
KM387_RS10675	COG1305	Transglutaminase-like
KM387_RS10680	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM387_RS10685	COG0714	Associated with various cellular activities
KM387_RS10700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM387_RS10705	COG1140	nitrate reductase beta subunit
KM387_RS10710	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM387_RS10715	COG2181	nitrate reductase activity
KM387_RS10725	COG1131	(ABC) transporter
KM387_RS10735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM387_RS10740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM387_RS10745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_RS10750	COG0303	'Molybdopterin
KM387_RS10755	COG0314	molybdopterin synthase activity
KM387_RS10765	COG2223	nitrite transmembrane transporter activity
KM387_RS10780	COG1648	precorrin-2 dehydrogenase activity
KM387_RS10790	COG1587	Uroporphyrinogen-III synthase
KM387_RS10790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM387_RS10795	COG2146	nitrite reductase [NAD(P)H] activity
KM387_RS10800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM387_RS10805	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM387_RS10840	COG2359	stage V sporulation protein S
KM387_RS10865	COG1418	mRNA catabolic process
KM387_RS10870	COG0488	(ABC) transporter
KM387_RS10885	COG0629	single-stranded DNA binding
KM387_RS10900	COG1413	lyase activity
KM387_RS10915	COG2136	Putative SAM-dependent methyltransferase
KM387_RS10915	COG2521	methyltransferase
KM387_RS10920	COG0018	arginyl-trna synthetase
KM387_RS10945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM387_RS10965	COG0017	Asparaginyl-tRNA synthetase
KM387_RS10985	COG1674	ftsk spoiiie
KM387_RS11055	COG1929	Belongs to the glycerate kinase type-1 family
KM387_RS11060	COG0471	metal ion transport
KM387_RS11065	COG0745	RESPONSE REGULATOR receiver
KM387_RS11070	COG3850	Histidine kinase
KM387_RS11070	COG5002	protein histidine kinase activity
KM387_RS11085	COG0733	neurotransmitter:sodium symporter activity
KM387_RS11110	COG2610	gluconate transmembrane transporter activity
KM387_RS11115	COG1454	alcohol dehydrogenase
KM387_RS11120	COG1794	racemase activity, acting on amino acids and derivatives
KM387_RS11130	COG0456	acetyltransferase
KM387_RS11145	COG1131	(ABC) transporter
KM387_RS11150	COG4473	ABC transporter
KM387_RS11160	COG0546	phosphoglycolate phosphatase activity
KM387_RS11180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_RS11195	COG0768	penicillin binding
KM387_RS11200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM387_RS11205	COG0204	Acyl-transferase
KM387_RS11210	COG1272	protein, Hemolysin III
KM387_RS11220	COG0805	protein transport
KM387_RS11230	COG1307	EDD domain protein, DegV family
KM387_RS11235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM387_RS11240	COG1999	signal sequence binding
KM387_RS11245	COG0071	Belongs to the small heat shock protein (HSP20) family
KM387_RS11250	COG0367	asparagine synthase
KM387_RS11265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS11270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM387_RS11300	COG0071	Belongs to the small heat shock protein (HSP20) family
KM387_RS11305	COG0668	transmembrane transport
KM387_RS11310	COG2203	Gaf domain
KM387_RS11310	COG4585	Histidine kinase
KM387_RS11315	COG2197	response regulator
KM387_RS11325	COG1064	alcohol dehydrogenase
KM387_RS11380	COG0517	IMP dehydrogenase activity
KM387_RS11380	COG1125	glycine betaine transport
KM387_RS11385	COG1174	glycine betaine transport
KM387_RS11420	COG1253	flavin adenine dinucleotide binding
KM387_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS11430	COG5506	Protein of unknown function (DUF1694)
KM387_RS11445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM387_RS11450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM387_RS11455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM387_RS11460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM387_RS11465	COG0456	acetyltransferase
KM387_RS11470	COG3829	transcription factor binding
KM387_RS11475	COG1509	lysine 2,3-aminomutase activity
KM387_RS11515	COG4326	sporulation control protein
KM387_RS11520	COG0671	phosphoesterase, PA-phosphatase related
KM387_RS11525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM387_RS11530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_RS11560	COG1715	Restriction endonuclease
KM387_RS11560	COG1787	Restriction endonuclease
KM387_RS11650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM387_RS11690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_RS11690	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM387_RS11700	COG2814	Major facilitator Superfamily
KM387_RS11705	COG4841	protein insertion into membrane
KM387_RS11710	COG0372	Belongs to the citrate synthase family
KM387_RS11715	COG2079	MmgE PrpD family protein
KM387_RS11720	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM387_RS11725	COG1960	acyl-CoA dehydrogenase activity
KM387_RS11730	COG2084	Dehydrogenase
KM387_RS11740	COG1280	lysine exporter protein (LysE YggA)
KM387_RS11745	COG1024	Enoyl-CoA hydratase
KM387_RS11760	COG0420	3'-5' exonuclease activity
KM387_RS11765	COG0419	ATPase involved in DNA repair
KM387_RS11785	COG2223	nitrite transmembrane transporter activity
KM387_RS11790	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS11795	COG1169	isochorismate synthase
KM387_RS11800	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM387_RS11805	COG3433	isochorismatase activity
KM387_RS11805	COG1535	isochorismatase
KM387_RS11810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM387_RS11815	COG3251	PFAM MbtH domain protein
KM387_RS11820	COG2814	Major facilitator Superfamily
KM387_RS11835	COG0776	regulation of translation
KM387_RS11845	COG2318	DinB family
KM387_RS11855	COG1115	amino acid carrier protein
KM387_RS11870	COG2329	Antibiotic biosynthesis monooxygenase
KM387_RS11875	COG1187	pseudouridine synthase activity
KM387_RS11880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM387_RS11885	COG1136	(ABC) transporter
KM387_RS11895	COG0596	Alpha beta hydrolase
KM387_RS11900	COG2814	Major facilitator Superfamily
KM387_RS11920	COG2226	methyltransferase
KM387_RS11965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS12000	COG1247	-acetyltransferase
KM387_RS12030	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM387_RS12040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS12050	COG1278	Cold shock
KM387_RS12065	COG0010	Belongs to the arginase family
KM387_RS12070	COG0561	phosphatase activity
KM387_RS12115	COG0583	DNA-binding transcription factor activity
KM387_RS12120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM387_RS12135	COG0583	DNA-binding transcription factor activity
KM387_RS12140	COG2258	MOSC domain
KM387_RS12155	COG1132	(ABC) transporter
KM387_RS12160	COG1132	(ABC) transporter
KM387_RS12180	COG1396	sequence-specific DNA binding
KM387_RS12205	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM387_RS12210	COG1595	DNA-templated transcription, initiation
KM387_RS12235	COG1649	PFAM Uncharacterised BCR, COG1649
KM387_RS12260	COG2971	BadF BadG BcrA BcrD
KM387_RS12265	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM387_RS12270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM387_RS12290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS12320	COG1309	transcriptional regulator
KM387_RS12335	COG1136	(ABC) transporter
KM387_RS12335	COG0577	efflux transmembrane transporter activity
KM387_RS12340	COG3615	Tellurite resistance protein tehB
KM387_RS12340	COG0500	methyltransferase
KM387_RS12350	COG2226	methyltransferase
KM387_RS12355	COG3961	Belongs to the TPP enzyme family
KM387_RS12360	COG1846	Transcriptional regulator
KM387_RS12400	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM387_RS12415	COG1595	DNA-templated transcription, initiation
KM387_RS12425	COG0768	penicillin binding
KM387_RS12430	COG0768	penicillin binding
KM387_RS12435	COG2367	Beta-lactamase
KM387_RS12440	COG0671	phosphoesterase, PA-phosphatase related
KM387_RS12445	COG1609	Transcriptional regulator
KM387_RS12450	COG2814	Major facilitator Superfamily
KM387_RS12455	COG0673	inositol 2-dehydrogenase activity
KM387_RS12480	COG0191	fructose-bisphosphate aldolase activity
KM387_RS12485	COG3718	enzyme involved in inositol metabolism
KM387_RS12500	COG0737	Belongs to the 5'-nucleotidase family
KM387_RS12510	COG0457	Tetratricopeptide repeat
KM387_RS12515	COG1476	TRANSCRIPTIONal
KM387_RS12530	COG1876	peptidase activity
KM387_RS12550	COG1309	transcriptional regulator
KM387_RS12555	COG0488	(ABC) transporter
KM387_RS12570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS12585	COG1252	NADH dehydrogenase
KM387_RS12590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_RS12605	COG1131	(ABC) transporter
KM387_RS12615	COG1309	transcriptional regulator
KM387_RS12630	COG1960	acyl-CoA dehydrogenase activity
KM387_RS12635	COG0439	Biotin carboxylase
KM387_RS12640	COG0511	ligase activity, forming carbon-carbon bonds
KM387_RS12645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM387_RS12650	COG1024	Enoyl-CoA hydratase
KM387_RS12655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM387_RS12660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM387_RS12670	COG1247	-acetyltransferase
KM387_RS12675	COG0572	uridine kinase
KM387_RS12685	COG2318	DinB family
KM387_RS12690	COG1686	Belongs to the peptidase S11 family
KM387_RS12715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM387_RS12755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM387_RS12755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM387_RS12780	COG2814	Major facilitator Superfamily
KM387_RS12800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM387_RS12820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS12835	COG1063	alcohol dehydrogenase
KM387_RS12850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM387_RS12865	COG3773	Cell wall hydrolase
KM387_RS12875	COG0745	RESPONSE REGULATOR receiver
KM387_RS12890	COG0488	(ABC) transporter
KM387_RS12905	COG1136	(ABC) transporter
KM387_RS12910	COG0577	efflux transmembrane transporter activity
KM387_RS12930	COG0460	homoserine dehydrogenase
KM387_RS12935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS12945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM387_RS13010	COG2124	cytochrome p450
KM387_RS13045	COG0561	phosphatase activity
KM387_RS13055	COG0768	penicillin binding
KM387_RS13060	COG1819	glycosyl
KM387_RS13065	COG1794	racemase activity, acting on amino acids and derivatives
KM387_RS13075	COG1122	ATPase activity
KM387_RS13090	COG2205	protein histidine kinase activity
KM387_RS13100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_RS13105	COG0604	alcohol dehydrogenase
KM387_RS13110	COG0768	penicillin binding
KM387_RS13155	COG0693	protein deglycase activity
KM387_RS13185	COG2814	Major facilitator Superfamily
KM387_RS13200	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_RS13220	COG0697	spore germination
KM387_RS13250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_RS13260	COG2223	nitrite transmembrane transporter activity
KM387_RS13275	COG2816	NAD+ diphosphatase activity
KM387_RS13280	COG0592	DNA-directed DNA polymerase activity
KM387_RS13285	COG1051	belongs to the nudix hydrolase family
KM387_RS13320	COG3878	Protein conserved in bacteria
KM387_RS13370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM387_RS13385	COG0322	excinuclease ABC activity
KM387_RS13425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_RS13450	COG1011	Hydrolase
KM387_RS13465	COG0657	acetylesterase activity
KM387_RS13470	COG0076	glutamate decarboxylase activity
KM387_RS13485	COG1523	belongs to the glycosyl hydrolase 13 family
KM387_RS13490	COG3227	Zinc metalloprotease (Elastase)
KM387_RS13510	COG0201	protein transport
KM387_RS13520	COG0697	spore germination
KM387_RS13525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS13555	COG4129	membrane
KM387_RS13560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS13575	COG2959	enzyme of heme biosynthesis
KM387_RS13595	COG3483	tryptophan 2,3-dioxygenase activity
KM387_RS13600	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM387_RS13605	COG3844	kynureninase activity
KM387_RS13610	COG1309	transcriptional regulator
KM387_RS13640	COG3284	Transcriptional regulator
KM387_RS13660	COG1349	DNA-binding transcription factor activity
KM387_RS13680	COG1959	2 iron, 2 sulfur cluster binding
KM387_RS13695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM387_RS13700	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_RS13705	COG0022	dehydrogenase e1 component
KM387_RS13710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM387_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS13725	COG0456	acetyltransferase
KM387_RS13725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_RS13755	COG4176	ABC-type proline glycine betaine transport system permease component
KM387_RS13760	COG4175	Glycine betaine
KM387_RS13760	COG0517	IMP dehydrogenase activity
KM387_RS13785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM387_RS13790	COG2153	protein acetylation
KM387_RS13795	COG3397	chitin binding
KM387_RS13810	COG2205	protein histidine kinase activity
KM387_RS13835	COG0658	competence protein
KM387_RS13835	COG2333	competence protein COMEC
KM387_RS13885	COG3973	AAA domain
KM387_RS13900	COG2105	PFAM AIG2 family protein
KM387_RS13905	COG0514	ATP-dependent DNA helicase (RecQ)
KM387_RS13925	COG4637	Psort location Cytoplasmic, score
KM387_RS13950	COG3397	chitin binding
KM387_RS13965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM387_RS13970	COG1115	amino acid carrier protein
KM387_RS13975	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS13980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM387_RS13990	COG3938	Belongs to the proline racemase family
KM387_RS13995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM387_RS14035	COG0586	Pfam SNARE associated Golgi protein
KM387_RS14050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM387_RS14055	COG0519	Catalyzes the synthesis of GMP from XMP
KM387_RS14060	COG4166	transmembrane transport
KM387_RS14070	COG4948	Mandelate Racemase Muconate Lactonizing
KM387_RS14115	COG2936	dipeptidyl-peptidase activity
KM387_RS14120	COG5002	protein histidine kinase activity
KM387_RS14125	COG0745	RESPONSE REGULATOR receiver
KM387_RS14160	COG1164	Oligoendopeptidase f
KM387_RS14170	COG1307	EDD domain protein, DegV family
KM387_RS14190	COG2814	Major facilitator Superfamily
KM387_RS14200	COG1664	Polymer-forming cytoskeletal
KM387_RS14205	COG0789	Transcriptional regulator
KM387_RS14210	COG4533	DNA binding
KM387_RS14215	COG0477	Major facilitator Superfamily
KM387_RS14215	COG2814	Major facilitator Superfamily
KM387_RS14235	COG2261	transglycosylase associated protein
KM387_RS14250	COG2226	methyltransferase
KM387_RS14285	COG0436	Aminotransferase
KM387_RS14290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM387_RS14295	COG5146	pantothenate kinase activity
KM387_RS14315	COG1131	(ABC) transporter
KM387_RS14360	COG0628	permease
KM387_RS14375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM387_RS14380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM387_RS14385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM387_RS14390	COG1116	anion transmembrane transporter activity
KM387_RS14410	COG2816	NAD+ diphosphatase activity
KM387_RS14430	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM387_RS14455	COG0697	spore germination
KM387_RS14460	COG2318	DinB family
KM387_RS14480	COG4912	Dna alkylation repair
KM387_RS14500	COG0861	Integral membrane protein TerC family
KM387_RS14505	COG1368	sulfuric ester hydrolase activity
KM387_RS14510	COG0488	(ABC) transporter
KM387_RS14520	COG1033	growth of symbiont in host cell
KM387_RS14520	COG2409	Drug exporters of the RND superfamily
KM387_RS14525	COG1309	transcriptional regulator
KM387_RS14540	COG0287	Prephenate dehydrogenase
KM387_RS14545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM387_RS14550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM387_RS14555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM387_RS14555	COG1605	Chorismate mutase
KM387_RS14590	COG1388	LysM domain
KM387_RS14590	COG3584	3D domain protein
KM387_RS14600	COG1595	DNA-templated transcription, initiation
KM387_RS14625	COG1879	ABC-type sugar transport system periplasmic component
KM387_RS14635	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM387_RS14645	COG2390	Transcriptional regulator
KM387_RS14650	COG1070	Carbohydrate kinase
KM387_RS14680	COG2329	Antibiotic biosynthesis monooxygenase
KM387_RS14700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS14710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM387_RS14715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_RS14720	COG4187	Peptidase family M20/M25/M40
KM387_RS14725	COG1414	Transcriptional regulator
KM387_RS14730	COG0833	amino acid
KM387_RS14735	COG1690	Belongs to the RtcB family
KM387_RS14740	COG3239	Fatty acid desaturase
KM387_RS14745	COG1785	Belongs to the alkaline phosphatase family
KM387_RS14755	COG3655	Transcriptional regulator
KM387_RS14770	COG4377	Putative membrane peptidase family (DUF2324)
KM387_RS14780	COG3279	Response regulator of the LytR AlgR family
KM387_RS14790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS14795	COG0346	lactoylglutathione lyase activity
KM387_RS14815	COG0714	Associated with various cellular activities
KM387_RS14840	COG0463	Glycosyl transferase, family 2
KM387_RS14860	COG0463	Glycosyl transferase, family 2
KM387_RS14870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM387_RS14875	COG0753	catalase activity
KM387_RS14885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM387_RS14910	COG0714	Associated with various cellular activities
KM387_RS14920	COG0778	Nitroreductase
KM387_RS14925	COG1846	Transcriptional regulator
KM387_RS14960	COG1725	Transcriptional regulator
KM387_RS14970	COG0577	efflux transmembrane transporter activity
KM387_RS14970	COG1136	(ABC) transporter
KM387_RS14995	COG2207	Transcriptional regulator
KM387_RS15000	COG0456	acetyltransferase
KM387_RS15020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS15040	COG0642	Histidine kinase
KM387_RS15045	COG0745	RESPONSE REGULATOR receiver
KM387_RS15050	COG0596	Alpha beta hydrolase
KM387_RS15080	COG0730	response to heat
KM387_RS15090	COG0833	amino acid
KM387_RS15100	COG4335	DNA alkylation repair
KM387_RS15150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM387_RS15180	COG1984	allophanate hydrolase subunit 2
KM387_RS15185	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM387_RS15190	COG1414	Transcriptional regulator
KM387_RS15205	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM387_RS15210	COG0640	Transcriptional regulator
KM387_RS15220	COG1960	acyl-CoA dehydrogenase activity
KM387_RS15235	COG3314	Sporulation integral membrane protein YlbJ
KM387_RS15250	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM387_RS15265	COG0574	Belongs to the PEP-utilizing enzyme family
KM387_RS15265	COG3848	Pyruvate phosphate dikinase
KM387_RS15270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS15285	COG5577	PFAM Coat F domain
KM387_RS15290	COG3403	YqcI/YcgG family
KM387_RS15295	COG1280	lysine exporter protein (LysE YggA)
KM387_RS15330	COG1063	alcohol dehydrogenase
KM387_RS15345	COG1027	Aspartate ammonia-lyase
KM387_RS15350	COG0252	asparaginase activity
KM387_RS15355	COG1396	sequence-specific DNA binding
KM387_RS15365	COG0322	excinuclease ABC activity
KM387_RS15375	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS15380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_RS15390	COG0281	malic enzyme
KM387_RS15405	COG0531	amino acid
KM387_RS15415	COG0784	Response regulator, receiver
KM387_RS15420	COG4191	Histidine kinase
KM387_RS15425	COG2066	Belongs to the glutaminase family
KM387_RS15430	COG1115	amino acid carrier protein
KM387_RS15460	COG0737	Belongs to the 5'-nucleotidase family
KM387_RS15465	COG0753	catalase activity
KM387_RS15470	COG2267	carboxylic ester hydrolase activity
KM387_RS15475	COG1335	isochorismatase
KM387_RS15495	COG0583	DNA-binding transcription factor activity
KM387_RS15505	COG0598	Magnesium transport protein CorA
KM387_RS15545	COG0415	Belongs to the DNA photolyase family
KM387_RS15550	COG0288	reversible hydration of carbon dioxide
KM387_RS15560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM387_RS15565	COG5609	conserved protein (DUF2294)
KM387_RS15580	COG1575	Belongs to the MenA family. Type 1 subfamily
KM387_RS15585	COG2267	carboxylic ester hydrolase activity
KM387_RS15590	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM387_RS15595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM387_RS15600	COG1121	(ABC) transporter
KM387_RS15630	COG0798	PFAM Bile acid sodium symporter
KM387_RS15635	COG0346	lactoylglutathione lyase activity
KM387_RS15640	COG0640	Transcriptional regulator
KM387_RS15655	COG0443	Heat shock 70 kDa protein
KM387_RS15670	COG1522	sequence-specific DNA binding
KM387_RS15685	COG0346	lactoylglutathione lyase activity
KM387_RS15705	COG2169	Transcriptional regulator
KM387_RS15750	COG2814	Major facilitator Superfamily
KM387_RS15775	COG0745	RESPONSE REGULATOR receiver
KM387_RS15780	COG5002	protein histidine kinase activity
KM387_RS15780	COG3850	Histidine kinase
KM387_RS15805	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM387_RS15825	COG1476	TRANSCRIPTIONal
KM387_RS15840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS15845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM387_RS15855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_RS15860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM387_RS15875	COG1136	(ABC) transporter
KM387_RS15880	COG0577	efflux transmembrane transporter activity
KM387_RS15895	COG3850	Histidine kinase
KM387_RS15895	COG5002	protein histidine kinase activity
KM387_RS15905	COG2364	Membrane
KM387_RS15910	COG1846	Transcriptional regulator
KM387_RS15915	COG0456	acetyltransferase
KM387_RS15920	COG2808	Putative FMN-binding domain
KM387_RS15925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS15930	COG2271	Major facilitator Superfamily
KM387_RS15935	COG1556	Lactate utilization protein
KM387_RS15940	COG1139	Iron-sulfur cluster binding protein
KM387_RS15950	COG0583	DNA-binding transcription factor activity
KM387_RS15960	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM387_RS15980	COG0738	Major facilitator superfamily
KM387_RS15985	COG0673	inositol 2-dehydrogenase activity
KM387_RS15990	COG0561	phosphatase activity
KM387_RS15995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM387_RS16000	COG1609	Transcriptional regulator
KM387_RS16005	COG0457	Tetratricopeptide repeat
KM387_RS16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM387_RS16055	COG0534	Mate efflux family protein
KM387_RS16075	COG2814	Major facilitator Superfamily
KM387_RS16080	COG1309	transcriptional regulator
KM387_RS16095	COG0814	amino acid
KM387_RS16100	COG1760	l-serine dehydratase
KM387_RS16105	COG1760	l-serine dehydratase
KM387_RS16115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM387_RS16120	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM387_RS16130	COG1335	isochorismatase
KM387_RS16135	COG1522	sequence-specific DNA binding
KM387_RS16140	COG0531	amino acid
KM387_RS16160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM387_RS16180	COG1595	DNA-templated transcription, initiation
KM387_RS16195	COG0662	Cupin 2, conserved barrel domain protein
KM387_RS16200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS16200	COG2207	Transcriptional regulator
KM387_RS16215	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_RS16215	COG3409	Peptidoglycan-binding domain 1 protein
KM387_RS16250	COG0477	Major facilitator Superfamily
KM387_RS16260	COG1846	Transcriptional regulator
KM387_RS16265	COG2814	Major facilitator Superfamily
KM387_RS16275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM387_RS16300	COG2076	Multidrug Resistance protein
KM387_RS16305	COG1309	transcriptional regulator
KM387_RS16315	COG2031	fatty acid transporter
KM387_RS16325	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM387_RS16355	COG1122	ATPase activity
KM387_RS16360	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM387_RS16375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM387_RS16380	COG1288	antiporter activity
KM387_RS16385	COG2356	endonuclease I
KM387_RS16400	COG3620	sequence-specific DNA binding
KM387_RS16405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM387_RS16410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM387_RS16415	COG0124	histidyl-tRNA synthetase
KM387_RS16430	COG1733	regulation of RNA biosynthetic process
KM387_RS16435	COG0778	Nitroreductase
KM387_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS16465	COG1131	(ABC) transporter
KM387_RS16490	COG1011	Hydrolase
KM387_RS16500	COG2365	Tyrosine phosphatase family
KM387_RS16525	COG0346	lactoylglutathione lyase activity
KM387_RS16530	COG1940	carbohydrate kinase activity
KM387_RS16535	COG0738	Major facilitator superfamily
KM387_RS16540	COG0110	maltose O-acetyltransferase activity
KM387_RS16550	COG1136	(ABC) transporter
KM387_RS16550	COG0577	efflux transmembrane transporter activity
KM387_RS16570	COG0628	permease
KM387_RS16590	COG2226	methyltransferase
KM387_RS16600	COG0477	Major facilitator Superfamily
KM387_RS16630	COG1253	flavin adenine dinucleotide binding
KM387_RS16635	COG0789	Transcriptional regulator
KM387_RS16640	COG0697	spore germination
KM387_RS16645	COG1357	PFAM Pentapeptide repeats (8 copies)
KM387_RS16650	COG3813	Protein conserved in bacteria
KM387_RS16655	COG2706	6-phosphogluconolactonase activity
KM387_RS16660	COG1070	Carbohydrate kinase
KM387_RS16670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM387_RS16675	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM387_RS16685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM387_RS16690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM387_RS16695	COG0604	alcohol dehydrogenase
KM387_RS16700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM387_RS16715	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS16740	COG0656	L-ascorbic acid biosynthetic process
KM387_RS16745	COG2814	Major facilitator Superfamily
KM387_RS16760	COG0346	lactoylglutathione lyase activity
KM387_RS16765	COG0814	amino acid
KM387_RS16790	COG1393	Belongs to the ArsC family
KM387_RS16795	COG1733	regulation of RNA biosynthetic process
KM387_RS16800	COG2188	Transcriptional regulator
KM387_RS16805	COG0673	inositol 2-dehydrogenase activity
KM387_RS16810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM387_RS16815	COG1733	regulation of RNA biosynthetic process
KM387_RS16820	COG1733	regulation of RNA biosynthetic process
KM387_RS16835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS16855	COG0384	phenazine biosynthesis protein PhzF
KM387_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS16885	COG1733	regulation of RNA biosynthetic process
KM387_RS16915	COG1191	sigma factor activity
KM387_RS16930	COG1309	transcriptional regulator
KM387_RS16950	COG3152	Membrane
KM387_RS16975	COG1151	hydroxylamine reductase activity
KM387_RS16985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS16990	COG3409	Peptidoglycan-binding domain 1 protein
KM387_RS16990	COG3757	hydrolase, family 25
KM387_RS17025	COG2072	flavoprotein involved in K transport
KM387_RS17060	COG0604	alcohol dehydrogenase
KM387_RS17065	COG1113	amino acid transport
KM387_RS17070	COG2814	Major facilitator Superfamily
KM387_RS17100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM387_RS17105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM387_RS17125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS17130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS17135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS17140	COG3739	integral membrane protein
KM387_RS17145	COG0384	phenazine biosynthesis protein PhzF
KM387_RS17175	COG0583	DNA-binding transcription factor activity
KM387_RS17195	COG1193	negative regulation of DNA recombination
KM387_RS17210	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KM387_RS17215	COG1164	Oligoendopeptidase f
KM387_RS17220	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM387_RS17250	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_RS17275	COG0640	Transcriptional regulator
KM387_RS17280	COG0604	alcohol dehydrogenase
KM387_RS17290	COG0457	Tetratricopeptide repeat
KM387_RS17300	COG2808	Putative FMN-binding domain
KM387_RS17305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_RS17315	COG0385	Bile acid
KM387_RS17320	COG0277	FAD linked oxidase domain protein
KM387_RS17350	COG1216	Glycosyl transferase, family 2
KM387_RS17355	COG1024	Enoyl-CoA hydratase
KM387_RS17365	COG1285	pathogenesis
KM387_RS17380	COG2514	catechol 2,3-dioxygenase activity
KM387_RS17385	COG2720	vancomycin resistance protein
KM387_RS17425	COG0716	FMN binding
KM387_RS17455	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS17465	COG0165	Argininosuccinate lyase
KM387_RS17480	COG4145	pantothenate transmembrane transporter activity
KM387_RS17490	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS17505	COG1657	PFAM Prenyltransferase squalene oxidase
KM387_RS17510	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM387_RS17515	COG2962	Rard protein
KM387_RS17520	COG3326	Membrane
KM387_RS17535	COG0489	protein tyrosine kinase activity
KM387_RS17545	COG0314	molybdopterin synthase activity
KM387_RS17550	COG0303	'Molybdopterin
KM387_RS17555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_RS17560	COG2116	formate transmembrane transporter activity
KM387_RS17570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM387_RS17575	COG5609	conserved protein (DUF2294)
KM387_RS17580	COG2427	Protein of unknown function (DUF1641)
KM387_RS17585	COG3383	formate dehydrogenase (NAD+) activity
KM387_RS17595	COG0697	spore germination
KM387_RS17635	COG2226	methyltransferase
KM387_RS17640	COG4166	transmembrane transport
KM387_RS17645	COG4166	transmembrane transport
KM387_RS17650	COG4166	transmembrane transport
KM387_RS17655	COG1301	dicarboxylic acid transport
KM387_RS17660	COG1316	TRANSCRIPTIONal
KM387_RS17670	COG1595	DNA-templated transcription, initiation
KM387_RS17690	COG1131	(ABC) transporter
KM387_RS17700	COG0673	inositol 2-dehydrogenase activity
KM387_RS17705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM387_RS17710	COG0187	DNA topoisomerase II activity
KM387_RS17715	COG1832	CoA-binding protein
KM387_RS17720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM387_RS17725	COG0745	RESPONSE REGULATOR receiver
KM387_RS17740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM387_RS17745	COG4841	protein insertion into membrane
KM387_RS17750	COG0824	Thioesterase
KM387_RS17780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_RS17790	COG2274	protein secretion by the type I secretion system
KM387_RS17795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM387_RS17835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM387_RS17855	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_RS17860	COG1268	BioY protein
KM387_RS17865	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_RS17915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS17925	COG5002	protein histidine kinase activity
KM387_RS17930	COG0400	carboxylic ester hydrolase activity
KM387_RS17935	COG0346	lactoylglutathione lyase activity
KM387_RS17940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM387_RS17945	COG0069	glutamate synthase activity
KM387_RS17950	COG1902	pentaerythritol trinitrate reductase activity
KM387_RS17955	COG1329	Transcriptional regulator
KM387_RS17960	COG0010	Belongs to the arginase family
KM387_RS17985	COG2226	methyltransferase
KM387_RS18020	COG4846	Membrane protein involved in cytochrome C biogenesis
KM387_RS18025	COG0785	Cytochrome C biogenesis protein
KM387_RS18035	COG1473	amidohydrolase
KM387_RS18045	COG1131	(ABC) transporter
KM387_RS18055	COG0583	DNA-binding transcription factor activity
KM387_RS18065	COG1346	cytolysis
KM387_RS18090	COG3409	Peptidoglycan-binding domain 1 protein
KM387_RS18090	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_RS18105	COG1132	(ABC) transporter
KM387_RS18110	COG1132	(ABC) transporter
KM387_RS18140	COG3639	organic phosphonate transmembrane transporter activity
KM387_RS18145	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM387_RS18165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM387_RS18185	COG1695	Transcriptional regulator
KM387_RS18225	COG3409	Peptidoglycan-binding domain 1 protein
KM387_RS18225	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM387_RS18225	COG1388	LysM domain
KM387_RS18230	COG4824	toxin secretion phage lysis holin
KM387_RS18380	COG1595	DNA-templated transcription, initiation
KM387_RS18425	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM387_RS18505	COG1396	sequence-specific DNA binding
KM387_RS18525	COG0174	glutamine synthetase
KM387_RS18530	COG0789	Transcriptional regulator
KM387_RS18535	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM387_RS18540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM387_RS18545	COG2860	membrane
KM387_RS18550	COG0464	growth
KM387_RS18580	COG3584	3D domain protein
KM387_RS18580	COG1388	LysM domain
KM387_RS18590	COG1105	Belongs to the carbohydrate kinase PfkB family
KM387_RS18595	COG1349	DNA-binding transcription factor activity
KM387_RS18605	COG2322	membrane
KM387_RS18615	COG1113	amino acid transport
KM387_RS18630	COG1408	metallophosphoesterase
KM387_RS18635	COG2116	formate transmembrane transporter activity
KM387_RS18645	COG2217	Heavy metal translocating P-type atpase
KM387_RS18650	COG2608	mercury ion transmembrane transporter activity
KM387_RS18655	COG1937	Protein conserved in bacteria
KM387_RS18665	COG2819	hydrolase of the alpha beta superfamily
KM387_RS18670	COG1120	ATPase activity
KM387_RS18675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS18680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS18690	COG0708	Exodeoxyribonuclease III
KM387_RS18695	COG2169	Transcriptional regulator
KM387_RS18700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM387_RS18705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM387_RS18715	COG2364	Membrane
KM387_RS18730	COG2267	carboxylic ester hydrolase activity
KM387_RS18735	COG0346	lactoylglutathione lyase activity
KM387_RS18740	COG3300	MHYT domain
KM387_RS18740	COG5001	Diguanylate cyclase
KM387_RS18760	COG1346	cytolysis
KM387_RS18765	COG1380	Effector of murein hydrolase LrgA
KM387_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM387_RS18775	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_RS18775	COG0596	Alpha beta hydrolase
KM387_RS18780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM387_RS18800	COG1404	Belongs to the peptidase S8 family
KM387_RS18805	COG3773	Cell wall hydrolase
KM387_RS18810	COG0562	UDP-galactopyranose mutase
KM387_RS18815	COG1368	sulfuric ester hydrolase activity
KM387_RS18820	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM387_RS18830	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM387_RS18855	COG1131	(ABC) transporter
KM387_RS18875	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM387_RS18880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM387_RS18885	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM387_RS18890	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM387_RS18890	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM387_RS18900	COG2359	stage V sporulation protein S
KM387_RS18905	COG1692	metallophosphoesterase
KM387_RS18930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM387_RS18935	COG1426	Protein conserved in bacteria
KM387_RS18950	COG0300	oxidoreductase activity
KM387_RS18955	COG0612	Peptidase, M16
KM387_RS18960	COG0612	Peptidase, M16
KM387_RS18965	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM387_RS18975	COG3845	ABC transporter
KM387_RS18980	COG1744	ABC transporter substrate-binding protein PnrA-like
KM387_RS18985	COG2188	Transcriptional regulator
KM387_RS18990	COG1674	ftsk spoiiie
KM387_RS19000	COG0740	serine-type endopeptidase activity
KM387_RS19005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM387_RS19020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM387_RS19025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM387_RS19030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM387_RS19035	COG1873	PFAM PRC-barrel domain
KM387_RS19040	COG0612	Peptidase, M16
KM387_RS19045	COG0726	polysaccharide deacetylase
KM387_RS19060	COG0196	riboflavin kinase activity
KM387_RS19065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM387_RS19075	COG1550	Protein conserved in bacteria
KM387_RS19085	COG1358	cellular component organization or biogenesis
KM387_RS19090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM387_RS19095	COG0195	Participates in both transcription termination and antitermination
KM387_RS19115	COG0750	zinc metalloprotease
KM387_RS19125	COG4589	Belongs to the CDS family
KM387_RS19140	COG0528	UMP kinase activity
KM387_RS19170	COG4974	Belongs to the 'phage' integrase family
KM387_RS19180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM387_RS19185	COG0758	DNA mediated transformation
KM387_RS19190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM387_RS19230	COG1837	Belongs to the UPF0109 family
KM387_RS19240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM387_RS19250	COG0552	protein localization to endoplasmic reticulum
KM387_RS19255	COG1196	nuclear chromosome segregation
KM387_RS19265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM387_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS19275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM387_RS19290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM387_RS19295	COG1461	Dihydroxyacetone kinase
KM387_RS19300	COG1302	Protein conserved in bacteria
KM387_RS19315	COG1564	THIamine pyrophosphokinase
KM387_RS19320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM387_RS19325	COG1162	GTPase activity
KM387_RS19330	COG2815	serine threonine protein kinase
KM387_RS19330	COG0515	serine threonine protein kinase
KM387_RS19335	COG0631	protein serine/threonine phosphatase activity
KM387_RS19345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM387_RS19345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM387_RS19355	COG0242	peptide deformylase activity
KM387_RS19360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM387_RS19365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM387_RS19385	COG1561	YicC-like family, N-terminal region
KM387_RS19390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM387_RS19400	COG0006	proline dipeptidase activity
KM387_RS19415	COG3069	C4-dicarboxylate transmembrane transporter activity
KM387_RS19480	COG0564	pseudouridine synthase activity
KM387_RS19500	COG3599	regulation of cell shape
KM387_RS19505	COG2302	S4 RNA-binding domain
KM387_RS19510	COG0762	integral membrane protein
KM387_RS19520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM387_RS19525	COG1496	oxidoreductase activity
KM387_RS19530	COG1873	PFAM PRC-barrel domain
KM387_RS19535	COG1191	sigma factor activity
KM387_RS19540	COG1191	sigma factor activity
KM387_RS19550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM387_RS19555	COG0849	cell division
KM387_RS19560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM387_RS19565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM387_RS19575	COG0772	Belongs to the SEDS family
KM387_RS19590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM387_RS19595	COG0768	penicillin binding
KM387_RS19600	COG0768	penicillin binding
KM387_RS19605	COG4839	cell division protein FtsL
KM387_RS19620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM387_RS19635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM387_RS19640	COG1399	metal-binding, possibly nucleic acid-binding protein
KM387_RS19690	COG4824	toxin secretion phage lysis holin
KM387_RS19775	COG1802	Transcriptional regulator
KM387_RS19775	COG4626	Terminase
KM387_RS19800	COG0582	viral genome integration into host DNA
KM387_RS19865	COG0756	dUTP diphosphatase activity
KM387_RS19880	COG1191	sigma factor activity
KM387_RS19905	COG1484	DNA-dependent DNA replication
KM387_RS19935	COG1396	sequence-specific DNA binding
KM387_RS19950	COG1396	sequence-specific DNA binding
KM387_RS19965	COG0582	viral genome integration into host DNA
KM387_RS19975	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM387_RS19980	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM387_RS19985	COG3314	Sporulation integral membrane protein YlbJ
KM387_RS19995	COG0742	ribosomal rna small subunit methyltransferase
KM387_RS20015	COG0406	alpha-ribazole phosphatase activity
KM387_RS20030	COG2340	Cysteine-rich secretory protein family
KM387_RS20045	COG3336	cytochrome c oxidase
KM387_RS20080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM387_RS20085	COG0772	Belongs to the SEDS family
KM387_RS20095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM387_RS20100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM387_RS20110	COG4896	Protein conserved in bacteria
KM387_RS20125	COG1217	gtp-binding protein TYPA
KM387_RS20135	COG0483	inositol monophosphate 1-phosphatase activity
KM387_RS20155	COG1982	Orn Lys Arg decarboxylase major
KM387_RS20205	COG0022	dehydrogenase e1 component
KM387_RS20210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM387_RS20220	COG0242	peptide deformylase activity
KM387_RS20225	COG0561	phosphatase activity
KM387_RS20235	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM387_RS20240	COG0569	domain protein
KM387_RS20260	COG0583	DNA-binding transcription factor activity
KM387_RS20265	COG0517	IMP dehydrogenase activity
KM387_RS20275	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM387_RS20285	COG4703	Protein of unknown function (DUF1797)
KM387_RS20300	COG2200	EAL domain
KM387_RS20305	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS20310	COG1408	metallophosphoesterase
KM387_RS20320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM387_RS20355	COG2814	Major facilitator Superfamily
KM387_RS20375	COG3209	COG3209 Rhs family protein
KM387_RS20385	COG2205	protein histidine kinase activity
KM387_RS20395	COG0436	Aminotransferase
KM387_RS20400	COG1609	Transcriptional regulator
KM387_RS20405	COG3833	ABC-type maltose transport systems, permease component
KM387_RS20410	COG1175	transmembrane transport
KM387_RS20415	COG2182	Extracellular solute-binding protein
KM387_RS20425	COG0366	Alpha amylase catalytic
KM387_RS20430	COG3842	ATPase activity
KM387_RS20470	COG0183	Belongs to the thiolase family
KM387_RS20505	COG1695	Transcriptional regulator
KM387_RS20510	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS20520	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM387_RS20530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM387_RS20535	COG0436	Aminotransferase
KM387_RS20570	COG2084	Dehydrogenase
KM387_RS20580	COG2199	diguanylate cyclase activity
KM387_RS20585	COG0778	Nitroreductase
KM387_RS20610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM387_RS20610	COG2190	(PTS) system
KM387_RS20610	COG1263	PTS System
KM387_RS20615	COG3711	transcriptional antiterminator
KM387_RS20625	COG2188	Transcriptional regulator
KM387_RS20635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM387_RS20660	COG1547	Domain of unknown function (DUF309)
KM387_RS20665	COG0456	acetyltransferase
KM387_RS20675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM387_RS20680	COG4086	secreted protein
KM387_RS20685	COG0561	phosphatase activity
KM387_RS20690	COG0697	spore germination
KM387_RS20705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_RS20730	COG0733	neurotransmitter:sodium symporter activity
KM387_RS20750	COG1686	Belongs to the peptidase S11 family
KM387_RS20755	COG1725	Transcriptional regulator
KM387_RS20760	COG1131	(ABC) transporter
KM387_RS20775	COG1846	Transcriptional regulator
KM387_RS20790	COG0598	Magnesium transport protein CorA
KM387_RS20815	COG4974	Belongs to the 'phage' integrase family
KM387_RS20825	COG0735	belongs to the Fur family
KM387_RS20830	COG1300	Membrane
KM387_RS20850	COG0667	Aldo Keto reductase
KM387_RS20855	COG0656	L-ascorbic acid biosynthetic process
KM387_RS20860	COG0456	acetyltransferase
KM387_RS20860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM387_RS20870	COG4085	toxin activity
KM387_RS20870	COG0737	Belongs to the 5'-nucleotidase family
KM387_RS20870	COG1525	nuclease
KM387_RS20880	COG0596	Alpha beta hydrolase
KM387_RS20885	COG2056	Na+-H+ antiporter family
KM387_RS20890	COG1609	Transcriptional regulator
KM387_RS20895	COG0456	acetyltransferase
KM387_RS20900	COG1073	alpha beta
KM387_RS20915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM387_RS20915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM387_RS20920	COG0307	riboflavin synthase, alpha
KM387_RS20945	COG4106	trans-aconitate 2-methyltransferase activity
KM387_RS20950	COG1073	alpha beta
KM387_RS20950	COG2226	methyltransferase
KM387_RS20965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM387_RS20975	COG1757	Na H antiporter
KM387_RS20980	COG0737	Belongs to the 5'-nucleotidase family
KM387_RS20990	COG1522	sequence-specific DNA binding
KM387_RS21010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM387_RS21020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM387_RS21035	COG0300	oxidoreductase activity
KM387_RS21040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS21045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_RS21050	COG1760	l-serine dehydratase
KM387_RS21055	COG1760	l-serine dehydratase
KM387_RS21075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM387_RS21085	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM387_RS21090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS21105	COG1376	ErfK ybiS ycfS ynhG family protein
KM387_RS21110	COG4129	membrane
KM387_RS21115	COG1126	abc transporter atp-binding protein
KM387_RS21120	COG0765	amino acid transport
KM387_RS21125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM387_RS21140	COG2816	NAD+ diphosphatase activity
KM387_RS21145	COG0772	Belongs to the SEDS family
KM387_RS21150	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM387_RS21155	COG0022	dehydrogenase e1 component
KM387_RS21160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM387_RS21165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM387_RS21180	COG0280	phosphate acetyltransferase
KM387_RS21185	COG3829	transcription factor binding
KM387_RS21185	COG3290	protein histidine kinase activity
KM387_RS21195	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_RS21200	COG3093	addiction module antidote protein HigA
KM387_RS21210	COG0745	RESPONSE REGULATOR receiver
KM387_RS21215	COG0750	zinc metalloprotease
KM387_RS21220	COG0497	DNA recombination
KM387_RS21230	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM387_RS21240	COG0142	geranyltranstransferase activity
KM387_RS21265	COG1302	Protein conserved in bacteria
KM387_RS21270	COG0439	Biotin carboxylase
KM387_RS21275	COG0511	ligase activity, forming carbon-carbon bonds
KM387_RS21320	COG3854	ATPases associated with a variety of cellular activities
KM387_RS21345	COG0006	proline dipeptidase activity
KM387_RS21360	COG3872	metal-dependent enzyme
KM387_RS21370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM387_RS21390	COG0095	Lipoate-protein ligase
KM387_RS21395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_RS21400	COG1609	Transcriptional regulator
KM387_RS21410	COG2076	Multidrug Resistance protein
KM387_RS21415	COG2076	Multidrug Resistance protein
KM387_RS21450	COG1131	(ABC) transporter
KM387_RS21455	COG1725	Transcriptional regulator
KM387_RS21485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM387_RS21540	COG4970	Tfp pilus assembly protein FimT
KM387_RS21550	COG1459	type II secretion system
KM387_RS21555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM387_RS21605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM387_RS21610	COG0646	methionine synthase
KM387_RS21610	COG1410	methionine synthase
KM387_RS21615	COG0646	methionine synthase
KM387_RS21615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM387_RS21620	COG0626	cystathionine gamma-synthase activity
KM387_RS21625	COG0626	cystathionine gamma-synthase activity
KM387_RS21645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS21660	COG4483	Protein conserved in bacteria
KM387_RS21665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM387_RS21670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM387_RS21675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM387_RS21680	COG0704	Plays a role in the regulation of phosphate uptake
KM387_RS21690	COG0581	inorganic phosphate transmembrane transporter activity
KM387_RS21695	COG0573	inorganic phosphate transmembrane transporter activity
KM387_RS21700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM387_RS21705	COG0768	penicillin binding
KM387_RS21710	COG0477	Major facilitator Superfamily
KM387_RS21715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM387_RS21740	COG0735	belongs to the Fur family
KM387_RS21745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM387_RS21750	COG1121	(ABC) transporter
KM387_RS21755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS21785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM387_RS21790	COG2384	SAM-dependent methyltransferase
KM387_RS21795	COG2010	Cytochrome c
KM387_RS21800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM387_RS21805	COG0358	DNA primase activity
KM387_RS21820	COG0517	IMP dehydrogenase activity
KM387_RS21835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM387_RS21840	COG0295	cytidine deaminase activity
KM387_RS21845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM387_RS21855	COG1480	7TM receptor with intracellular HD hydrolase
KM387_RS21860	COG1702	phosphate starvation-inducible protein PhoH
KM387_RS21875	COG1610	YqeY-like protein
KM387_RS21880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM387_RS21885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM387_RS21890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM387_RS21920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM387_RS21925	COG1733	regulation of RNA biosynthetic process
KM387_RS21950	COG1466	dna polymerase III delta subunit
KM387_RS21960	COG2333	competence protein COMEC
KM387_RS21960	COG0658	competence protein
KM387_RS21965	COG2131	deaminase
KM387_RS21970	COG1596	polysaccharide export
KM387_RS21970	COG1555	photosystem II stabilization
KM387_RS21975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM387_RS21980	COG2226	methyltransferase
KM387_RS21985	COG0799	negative regulation of ribosome biogenesis
KM387_RS21990	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM387_RS22000	COG1534	Rna-binding protein
KM387_RS22010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM387_RS22015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM387_RS22040	COG1595	DNA-templated transcription, initiation
KM387_RS22050	COG0778	Nitroreductase
KM387_RS22065	COG1785	Belongs to the alkaline phosphatase family
KM387_RS22075	COG2267	carboxylic ester hydrolase activity
KM387_RS22110	COG1404	Belongs to the peptidase S8 family
KM387_RS22115	COG3186	Phenylalanine-4-hydroxylase
KM387_RS22125	COG2514	catechol 2,3-dioxygenase activity
KM387_RS22130	COG2259	Doxx family
KM387_RS22170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS22180	COG1454	alcohol dehydrogenase
KM387_RS22180	COG1012	belongs to the aldehyde dehydrogenase family
KM387_RS22185	COG0626	cystathionine gamma-synthase activity
KM387_RS22190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM387_RS22215	COG0768	penicillin binding
KM387_RS22230	COG0826	peptidase U32
KM387_RS22235	COG0826	peptidase U32
KM387_RS22240	COG4122	O-methyltransferase activity
KM387_RS22245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM387_RS22265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM387_RS22275	COG0628	permease
KM387_RS22295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM387_RS22310	COG1104	cysteine desulfurase activity
KM387_RS22315	COG1959	2 iron, 2 sulfur cluster binding
KM387_RS22320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM387_RS22330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM387_RS22355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM387_RS22365	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM387_RS22365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM387_RS22370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM387_RS22375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM387_RS22375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM387_RS22385	COG2244	polysaccharide biosynthetic process
KM387_RS22390	COG2323	membrane
KM387_RS22400	COG1862	Preprotein translocase
KM387_RS22430	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM387_RS22440	COG0697	spore germination
KM387_RS22445	COG0697	spore germination
KM387_RS22450	COG0640	Transcriptional regulator
KM387_RS22475	COG0157	Belongs to the NadC ModD family
KM387_RS22480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM387_RS22485	COG1104	cysteine desulfurase activity
KM387_RS22490	COG1827	regulation of RNA biosynthetic process
KM387_RS22495	COG2258	MOSC domain
KM387_RS22500	COG0077	Prephenate dehydratase
KM387_RS22505	COG0577	efflux transmembrane transporter activity
KM387_RS22510	COG0577	efflux transmembrane transporter activity
KM387_RS22515	COG1136	(ABC) transporter
KM387_RS22525	COG0745	RESPONSE REGULATOR receiver
KM387_RS22535	COG3290	protein histidine kinase activity
KM387_RS22545	COG2868	ribosomal protein
KM387_RS22555	COG1530	ribonuclease E activity
KM387_RS22560	COG1994	Peptidase M50
KM387_RS22565	COG0739	heme binding
KM387_RS22570	COG2894	cell division
KM387_RS22590	COG1077	Cell shape determining protein MreB Mrl
KM387_RS22610	COG0285	dihydrofolate synthase activity
KM387_RS22615	COG0525	valine-tRNA ligase activity
KM387_RS22625	COG1388	LysM domain
KM387_RS22635	COG0113	porphobilinogen synthase activity
KM387_RS22640	COG1587	Uroporphyrinogen-III synthase
KM387_RS22650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM387_RS22660	COG1846	Transcriptional regulator
KM387_RS22665	COG1764	response to oxidative stress
KM387_RS22680	COG0470	DNA polymerase III
KM387_RS22680	COG1067	ATP-dependent peptidase activity
KM387_RS22725	COG0622	Phosphoesterase
KM387_RS22740	COG5401	PFAM Sporulation and spore germination
KM387_RS22760	COG1309	transcriptional regulator
KM387_RS22775	COG2197	response regulator
KM387_RS22780	COG2233	PERMEase
KM387_RS22790	COG0402	S-adenosylhomocysteine deaminase activity
KM387_RS22795	COG0402	S-adenosylhomocysteine deaminase activity
KM387_RS22805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM387_RS22815	COG0444	Belongs to the ABC transporter superfamily
KM387_RS22820	COG4608	Belongs to the ABC transporter superfamily
KM387_RS22825	COG3275	phosphorelay sensor kinase activity
KM387_RS22830	COG3279	Response regulator of the LytR AlgR family
KM387_RS22840	COG1983	PspC domain protein
KM387_RS22845	COG1396	sequence-specific DNA binding
KM387_RS22850	COG0697	spore germination
KM387_RS22860	COG1959	2 iron, 2 sulfur cluster binding
KM387_RS22865	COG1668	transmembrane transport
KM387_RS22870	COG4152	abc transporter atp-binding protein
KM387_RS22875	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM387_RS22885	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM387_RS22890	COG1876	peptidase activity
KM387_RS22895	COG0824	Thioesterase
KM387_RS22900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM387_RS22905	COG1053	succinate dehydrogenase
KM387_RS22910	COG2009	succinate dehydrogenase
KM387_RS22915	COG1719	4-vinyl reductase, 4VR
KM387_RS22925	COG3118	belongs to the thioredoxin family
KM387_RS22930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM387_RS22935	COG2086	electron transfer activity
KM387_RS22940	COG1024	Enoyl-CoA hydratase
KM387_RS22945	COG1309	transcriptional regulator
KM387_RS22950	COG0318	PFAM AMP-dependent synthetase and ligase
KM387_RS22970	COG2318	DinB family
KM387_RS23000	COG1131	(ABC) transporter
KM387_RS23005	COG2205	protein histidine kinase activity
KM387_RS23010	COG0745	RESPONSE REGULATOR receiver
KM387_RS23020	COG4895	conserved protein (DUF2196)
KM387_RS23025	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM387_RS23040	COG4509	Sortase family
KM387_RS23045	COG1120	ATPase activity
KM387_RS23060	COG5386	Cell surface protein
KM387_RS23070	COG5386	Cell surface protein
KM387_RS23075	COG1114	Component of the transport system for branched-chain amino acids
KM387_RS23080	COG1187	pseudouridine synthase activity
KM387_RS23090	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM387_RS23090	COG1796	DNA polymerase
KM387_RS23095	COG1286	toxin biosynthetic process
KM387_RS23140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM387_RS23150	COG1418	mRNA catabolic process
KM387_RS23175	COG2814	Major facilitator Superfamily
KM387_RS23180	COG1566	PFAM secretion protein HlyD family protein
KM387_RS23185	COG1309	transcriptional regulator
KM387_RS23190	COG1363	Peptidase, m42
KM387_RS23215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM387_RS23225	COG1484	DNA-dependent DNA replication
KM387_RS23230	COG3611	Membrane attachment protein
KM387_RS23240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM387_RS23245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM387_RS23250	COG0237	dephospho-CoA kinase activity
KM387_RS23255	COG1971	Probably functions as a manganese efflux pump
KM387_RS23265	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM387_RS23265	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM387_RS23270	COG5002	protein histidine kinase activity
KM387_RS23275	COG0745	RESPONSE REGULATOR receiver
KM387_RS23295	COG0538	isocitrate dehydrogenase activity
KM387_RS23300	COG0372	Belongs to the citrate synthase family
KM387_RS23310	COG0628	permease
KM387_RS23315	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM387_RS23340	COG1725	Transcriptional regulator
KM387_RS23345	COG0281	malic enzyme
KM387_RS23350	COG0587	DNA-directed DNA polymerase activity
KM387_RS23365	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM387_RS23385	COG4109	DRTGG domain
KM387_RS23400	COG0006	proline dipeptidase activity
KM387_RS23440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS23445	COG0662	Cupin 2, conserved barrel domain protein
KM387_RS23455	COG1476	TRANSCRIPTIONal
KM387_RS23470	COG1028	Short-chain dehydrogenase reductase Sdr
KM387_RS23515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS23535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM387_RS23540	COG0827	DNA restriction-modification system
KM387_RS23545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM387_RS23550	COG3874	Sporulation protein YtfJ
KM387_RS23565	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM387_RS23575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM387_RS23590	COG1104	cysteine desulfurase activity
KM387_RS23600	COG0583	DNA-binding transcription factor activity
KM387_RS23605	COG0697	spore germination
KM387_RS23610	COG1309	transcriptional regulator
KM387_RS23615	COG1956	GAF domain-containing protein
KM387_RS23620	COG0626	cystathionine gamma-synthase activity
KM387_RS23650	COG1595	DNA-templated transcription, initiation
KM387_RS23660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM387_RS23665	COG0454	-acetyltransferase
KM387_RS23670	COG0517	IMP dehydrogenase activity
KM387_RS23675	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM387_RS23685	COG0745	RESPONSE REGULATOR receiver
KM387_RS23695	COG0666	response to abiotic stimulus
KM387_RS23730	COG1609	Transcriptional regulator
KM387_RS23735	COG4851	CamS sex pheromone cAM373 precursor
KM387_RS23740	COG3118	belongs to the thioredoxin family
KM387_RS23750	COG2309	aminopeptidase activity
KM387_RS23770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS23785	COG1674	ftsk spoiiie
KM387_RS23795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM387_RS23800	COG4848	Belongs to the UPF0354 family
KM387_RS23805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_RS23810	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM387_RS23815	COG1363	Peptidase, m42
KM387_RS23825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS23840	COG0510	thiamine kinase activity
KM387_RS23845	COG1523	belongs to the glycosyl hydrolase 13 family
KM387_RS23855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM387_RS23860	COG1349	DNA-binding transcription factor activity
KM387_RS23865	COG1187	pseudouridine synthase activity
KM387_RS23870	COG2244	polysaccharide biosynthetic process
KM387_RS23880	COG2814	Major facilitator Superfamily
KM387_RS23890	COG3832	glyoxalase III activity
KM387_RS23910	COG1329	Transcriptional regulator
KM387_RS23935	COG0314	molybdopterin synthase activity
KM387_RS23940	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM387_RS23945	COG0303	'Molybdopterin
KM387_RS23955	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM387_RS23960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM387_RS23980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM387_RS23990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM387_RS24030	COG2814	Major facilitator Superfamily
KM387_RS24035	COG0475	glutathione-regulated potassium exporter activity
KM387_RS24040	COG0490	domain, Protein
KM387_RS24045	COG0582	viral genome integration into host DNA
KM387_RS24055	COG1136	(ABC) transporter
KM387_RS24075	COG1242	4 iron, 4 sulfur cluster binding
KM387_RS24080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM387_RS24085	COG1131	(ABC) transporter
KM387_RS24095	COG1794	racemase activity, acting on amino acids and derivatives
KM387_RS24115	COG2267	carboxylic ester hydrolase activity
KM387_RS24120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM387_RS24125	COG0671	phosphoesterase, PA-phosphatase related
KM387_RS24130	COG0438	transferase activity, transferring glycosyl groups
KM387_RS24140	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM387_RS24195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM387_RS24200	COG5002	protein histidine kinase activity
KM387_RS24205	COG4191	Histidine kinase
KM387_RS24210	COG2267	carboxylic ester hydrolase activity
KM387_RS24215	COG1368	sulfuric ester hydrolase activity
KM387_RS24230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM387_RS24235	COG1116	anion transmembrane transporter activity
KM387_RS24265	COG0494	nUDIX hydrolase
KM387_RS24300	COG0288	reversible hydration of carbon dioxide
KM387_RS24305	COG1271	oxidase subunit
KM387_RS24310	COG1294	oxidase, subunit
KM387_RS24330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS24355	COG1842	Phage shock protein A
KM387_RS24385	COG5002	protein histidine kinase activity
KM387_RS24390	COG0745	RESPONSE REGULATOR receiver
KM387_RS24415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM387_RS24420	COG1597	lipid kinase activity
KM387_RS24455	COG0586	Pfam SNARE associated Golgi protein
KM387_RS24465	COG0577	efflux transmembrane transporter activity
KM387_RS24470	COG1136	(ABC) transporter
KM387_RS24475	COG3708	Transcriptional regulator
KM387_RS24475	COG2207	Transcriptional regulator
KM387_RS24480	COG0745	RESPONSE REGULATOR receiver
KM387_RS24485	COG2205	protein histidine kinase activity
KM387_RS24490	COG0577	efflux transmembrane transporter activity
KM387_RS24495	COG0577	efflux transmembrane transporter activity
KM387_RS24500	COG1136	(ABC) transporter
KM387_RS24505	COG0577	efflux transmembrane transporter activity
KM387_RS24520	COG2188	Transcriptional regulator
KM387_RS24540	COG3964	amidohydrolase
KM387_RS24570	COG4948	Mandelate Racemase Muconate Lactonizing
KM387_RS24580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM387_RS24585	COG0596	Alpha beta hydrolase
KM387_RS24590	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM387_RS24595	COG1169	isochorismate synthase
KM387_RS24600	COG1575	Belongs to the MenA family. Type 1 subfamily
KM387_RS24605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM387_RS24625	COG0058	SHG alpha-glucan phosphorylase activity
KM387_RS24630	COG0297	glycogen (starch) synthase activity
KM387_RS24635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM387_RS24750	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM387_RS24785	COG1285	pathogenesis
KM387_RS24790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM387_RS24800	COG0166	Belongs to the GPI family
KM387_RS24805	COG2155	Conserved Protein
KM387_RS24810	COG1098	S1 RNA binding domain
KM387_RS24815	COG0436	Aminotransferase
KM387_RS24820	COG1522	sequence-specific DNA binding
KM387_RS24825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM387_RS24830	COG2267	carboxylic ester hydrolase activity
KM387_RS24840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM387_RS24860	COG5018	Exonuclease
KM387_RS24865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM387_RS24885	COG2050	protein possibly involved in aromatic compounds catabolism
KM387_RS24895	COG1268	BioY protein
KM387_RS24905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM387_RS24910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM387_RS24925	COG3584	3D domain protein
KM387_RS24940	COG1252	NADH dehydrogenase
KM387_RS24955	COG3708	Transcriptional regulator
KM387_RS24970	COG1683	Conserved Protein
KM387_RS24990	COG0316	Belongs to the HesB IscA family
KM387_RS25005	COG1252	NADH dehydrogenase
KM387_RS25015	COG2274	protein secretion by the type I secretion system
KM387_RS25020	COG0390	transport system, permease component
KM387_RS25025	COG2824	Alkylphosphonate utilization operon protein PhnA
KM387_RS25065	COG4837	Protein of unknown function (DUF1462)
KM387_RS25070	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM387_RS25080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM387_RS25085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM387_RS25095	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM387_RS25100	COG0647	UMP catabolic process
KM387_RS25110	COG2445	Protein of unknown function DUF86
KM387_RS25115	COG1494	fructose-1,6-bisphosphatase
KM387_RS25130	COG4470	Protein conserved in bacteria
KM387_RS25140	COG0789	Transcriptional regulator
KM387_RS25145	COG4377	Putative membrane peptidase family (DUF2324)
KM387_RS25170	COG0739	heme binding
KM387_RS25180	COG3377	Domain of unknown function (DUF1805)
KM387_RS25185	COG0737	Belongs to the 5'-nucleotidase family
KM387_RS25190	COG1695	Transcriptional regulator
KM387_RS25200	COG0719	Fe-S assembly protein
KM387_RS25205	COG0822	iron-sulfur transferase activity
KM387_RS25210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM387_RS25215	COG0719	Fe-S assembly protein
KM387_RS25220	COG0396	ATPase activity
KM387_RS25225	COG1464	Belongs to the NlpA lipoprotein family
KM387_RS25230	COG1464	Belongs to the NlpA lipoprotein family
KM387_RS25235	COG2011	ABC-type metal ion transport system permease component
KM387_RS25240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM387_RS25250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM387_RS25255	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM387_RS25265	COG1393	Belongs to the ArsC family
KM387_RS25310	COG0039	L-malate dehydrogenase activity
KM387_RS25335	COG1309	transcriptional regulator
KM387_RS25340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM387_RS25345	COG1960	acyl-CoA dehydrogenase activity
KM387_RS25355	COG0183	Belongs to the thiolase family
KM387_RS25360	COG1024	Enoyl-CoA hydratase
KM387_RS25360	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM387_RS25370	COG1686	Belongs to the peptidase S11 family
KM387_RS25385	COG0011	TIGRFAM Protein of
KM387_RS25390	COG0840	transmembrane signaling receptor activity
KM387_RS25410	COG2814	Major facilitator Superfamily
KM387_RS25415	COG0531	amino acid
KM387_RS25425	COG0706	membrane insertase activity
KM387_RS25435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM387_RS25470	COG0586	Pfam SNARE associated Golgi protein
KM387_RS25480	COG1376	ErfK ybiS ycfS ynhG family protein
KM387_RS25485	COG0745	RESPONSE REGULATOR receiver
KM387_RS25490	COG5002	protein histidine kinase activity
KM387_RS25515	COG2151	metal-sulfur cluster biosynthetic enzyme
KM387_RS25520	COG3227	Zinc metalloprotease (Elastase)
KM387_RS25525	COG1741	Belongs to the pirin family
KM387_RS25540	COG0475	glutathione-regulated potassium exporter activity
KM387_RS25545	COG0490	domain, Protein
KM387_RS25550	COG1115	amino acid carrier protein
KM387_RS25555	COG0783	Belongs to the Dps family
KM387_RS25570	COG1611	Belongs to the LOG family
KM387_RS25590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS25595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS25600	COG1115	amino acid carrier protein
KM387_RS25605	COG1115	amino acid carrier protein
KM387_RS25610	COG2910	NAD(P)H-binding
KM387_RS25625	COG0656	L-ascorbic acid biosynthetic process
KM387_RS25630	COG2814	Major facilitator Superfamily
KM387_RS25635	COG1733	regulation of RNA biosynthetic process
KM387_RS25645	COG1252	NADH dehydrogenase
KM387_RS25650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM387_RS25655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM387_RS25665	COG0840	transmembrane signaling receptor activity
KM387_RS25665	COG3290	protein histidine kinase activity
KM387_RS25675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM387_RS25680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM387_RS25695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM387_RS25750	COG0557	exoribonuclease II activity
KM387_RS25755	COG1647	Serine aminopeptidase, S33
KM387_RS25760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM387_RS25765	COG1346	cytolysis
KM387_RS25865	COG4695	Portal protein
KM387_RS25885	COG4974	Belongs to the 'phage' integrase family
KM387_RS25900	COG0149	triose-phosphate isomerase activity
KM387_RS25910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM387_RS25925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM387_RS25950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM387_RS25965	COG2323	membrane
KM387_RS25975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM387_RS25985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM387_RS25995	COG1051	belongs to the nudix hydrolase family
KM387_RS26005	COG0492	ferredoxin-NADP+ reductase activity
KM387_RS26010	COG0457	Tetratricopeptide repeat
KM387_RS26015	COG0110	maltose O-acetyltransferase activity
KM387_RS26035	COG1950	PFAM Membrane protein of
KM387_RS26045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM387_RS26050	COG0556	nucleotide-excision repair
KM387_RS26070	COG0789	Transcriptional regulator
KM387_RS26095	COG2855	membrane
KM387_RS26100	COG0583	DNA-binding transcription factor activity
KM387_RS26110	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM387_RS26115	COG0488	(ABC) transporter
KM387_RS26125	COG1132	(ABC) transporter
KM387_RS26130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM387_RS26135	COG0793	Belongs to the peptidase S41A family
KM387_RS26135	COG3409	Peptidoglycan-binding domain 1 protein
KM387_RS26140	COG2177	Part of the ABC transporter FtsEX involved in
KM387_RS26145	COG2884	Cell division ATP-binding protein ftsE
KM387_RS26160	COG0653	protein targeting
KM387_RS26165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM387_RS26170	COG1278	Cold shock
KM387_RS26175	COG1040	competence protein
KM387_RS26180	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM387_RS26185	COG1388	LysM domain
KM387_RS26185	COG0791	NLP P60 protein
KM387_RS26190	COG1733	regulation of RNA biosynthetic process
KM387_RS26195	COG1307	EDD domain protein, DegV family
KM387_RS26200	COG1739	Uncharacterized protein family UPF0029
KM387_RS26205	COG1316	TRANSCRIPTIONal
KM387_RS26210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM387_RS26220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM387_RS26230	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM387_RS26230	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM387_RS26245	COG3394	polysaccharide catabolic process
KM387_RS26250	COG1486	melibiose metabolic process
KM387_RS26255	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM387_RS26260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM387_RS26270	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM387_RS26275	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM387_RS26280	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM387_RS26290	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM387_RS26295	COG1301	dicarboxylic acid transport
KM387_RS26305	COG0346	lactoylglutathione lyase activity
KM387_RS26310	COG1511	domain protein
KM387_RS26315	COG0583	DNA-binding transcription factor activity
KM387_RS26320	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM387_RS26335	COG1271	oxidase subunit
KM387_RS26340	COG1294	oxidase, subunit
KM387_RS26345	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM387_RS26365	COG2389	metal-binding protein
KM387_RS26375	COG1368	sulfuric ester hydrolase activity
KM387_RS26390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM387_RS26400	COG1215	transferase activity, transferring glycosyl groups
KM387_RS26405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM387_RS26410	COG3584	3D domain protein
KM387_RS26410	COG1388	LysM domain
KM387_RS26435	COG4715	Zinc finger, swim domain protein
KM387_RS26440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM387_RS26480	COG0577	efflux transmembrane transporter activity
KM387_RS26485	COG1136	(ABC) transporter
KM387_RS26520	COG5002	protein histidine kinase activity
KM387_RS26525	COG0745	RESPONSE REGULATOR receiver
KM387_RS26530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM387_RS26550	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM387_RS26555	COG1134	teichoic acid transport
KM387_RS26560	COG1682	transport, permease protein
KM387_RS26565	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM387_RS26605	COG1609	Transcriptional regulator
KM387_RS26620	COG0739	heme binding
KM387_RS26635	COG3279	Response regulator of the LytR AlgR family
KM387_RS26640	COG2385	sporulation resulting in formation of a cellular spore
KM387_RS26655	COG4836	Membrane
KM387_RS26660	COG1007	ATP synthesis coupled electron transport
KM387_RS26665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM387_RS26670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM387_RS26680	COG0839	Belongs to the complex I subunit 6 family
KM387_RS26695	COG0649	NAD binding
KM387_RS26700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM387_RS26715	COG5001	Diguanylate cyclase
KM387_RS26715	COG3300	MHYT domain
KM387_RS26765	COG0356	it plays a direct role in the translocation of protons across the membrane
KM387_RS26800	COG0698	ribose 5-phosphate isomerase
KM387_RS26810	COG2190	(PTS) system
KM387_RS26815	COG2259	Doxx family
KM387_RS26820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM387_RS26835	COG0009	L-threonylcarbamoyladenylate synthase
KM387_RS26850	COG2890	protein-(glutamine-N5) methyltransferase activity
KM387_RS26870	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM387_RS26875	COG1494	fructose-1,6-bisphosphatase
KM387_RS26895	COG4821	SIS domain
KM387_RS26915	COG1960	acyl-CoA dehydrogenase activity
KM387_RS26920	COG1960	acyl-CoA dehydrogenase activity
KM387_RS26925	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM387_RS26930	COG0183	Belongs to the thiolase family
KM387_RS26935	COG2181	nitrate reductase activity
KM387_RS26935	COG0247	lactate metabolic process
KM387_RS26940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM387_RS26950	COG5001	Diguanylate cyclase
KM387_RS26950	COG3300	MHYT domain
KM387_RS26970	COG2197	response regulator
KM387_RS26975	COG4585	Histidine kinase
KM387_RS26980	COG0842	Transport permease protein
KM387_RS26985	COG1131	(ABC) transporter
KM387_RS26990	COG0024	Methionine aminopeptidase
KM387_RS27000	COG2234	aminopeptidase activity
KM387_RS27020	COG1595	DNA-templated transcription, initiation
KM387_RS27030	COG4506	Protein conserved in bacteria
KM387_RS27035	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM387_RS27050	COG0010	Belongs to the arginase family
KM387_RS27060	COG2814	Major facilitator Superfamily
KM387_RS27065	COG0789	Transcriptional regulator
KM387_RS27070	COG0584	glycerophosphoryl diester phosphodiesterase
KM387_RS27075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM387_RS27085	COG1994	Peptidase M50
KM387_RS27095	COG1078	dGTPase activity
KM387_RS27100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM387_RS27105	COG1120	ATPase activity
KM387_RS27110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS27115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM387_RS27135	COG0095	Lipoate-protein ligase
KM387_RS27140	COG0280	phosphate acetyltransferase
KM387_RS27155	COG3773	Cell wall hydrolase
KM387_RS27165	COG2363	Small membrane protein
KM387_RS27175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM387_RS27180	COG2233	PERMEase
KM387_RS27185	COG0561	phosphatase activity
KM387_RS27190	COG2814	Major facilitator Superfamily
KM387_RS27200	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM387_RS27205	COG1131	(ABC) transporter
KM387_RS27210	COG2755	lipolytic protein G-D-S-L family
KM387_RS27215	COG1609	Transcriptional regulator
KM387_RS27225	COG0460	homoserine dehydrogenase
KM387_RS27235	COG2873	o-acetylhomoserine
KM387_RS27245	COG1011	Hydrolase
KM387_RS27250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM387_RS27260	COG2197	response regulator
KM387_RS27270	COG0351	phosphomethylpyrimidine kinase
KM387_RS27275	COG3706	GGDEF domain
KM387_RS27280	COG2879	small protein
KM387_RS27285	COG1966	Carbon starvation protein
KM387_RS27290	COG3279	Response regulator of the LytR AlgR family
KM387_RS27295	COG0477	Major facilitator Superfamily
KM387_RS27320	COG0840	transmembrane signaling receptor activity
KM387_RS27330	COG1607	acyl-coa hydrolase
KM387_RS27345	COG0488	(ABC) transporter
KM387_RS27365	COG0463	Glycosyl transferase, family 2
KM387_RS27370	COG1309	transcriptional regulator
KM387_RS27375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM387_RS27380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM387_RS27380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM387_RS27385	COG0628	permease
KM387_RS27400	COG3279	Response regulator of the LytR AlgR family
KM387_RS27405	COG3275	phosphorelay sensor kinase activity
KM387_RS27410	COG2814	Major facilitator Superfamily
KM387_RS27415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM387_RS27420	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM387_RS27425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM387_RS27445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM387_RS27450	COG1272	protein, Hemolysin III
KM387_RS27475	COG1164	Oligoendopeptidase f
KM387_RS27495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM387_RS27500	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM387_RS27505	COG4853	Protein conserved in bacteria
KM387_RS27510	COG4863	YycH protein
KM387_RS27515	COG5002	protein histidine kinase activity
KM387_RS27520	COG0745	RESPONSE REGULATOR receiver
KM387_RS27550	COG0305	Participates in initiation and elongation during chromosome replication
KM387_RS27560	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM387_RS27565	COG4241	membrane
KM387_RS27575	COG0629	single-stranded DNA binding
KM387_RS27585	COG0012	GTP binding
KM387_RS27590	COG4481	Protein conserved in bacteria
KM387_RS27595	COG0668	transmembrane transport
KM387_RS27605	COG1475	DNA binding
KM387_RS27610	COG1192	Involved in chromosome partitioning
KM387_RS27635	COG1847	R3H domain protein
KM387_RS27640	COG0706	membrane insertase activity
KM387_RS27650	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM387_RS27705	COG3344	reverse transcriptase
KM387_RS27785	COG3344	reverse transcriptase
KM387_RS27990	COG4962	Type ii secretion system protein e
KM387_RS28130	COG2311	Membrane
KM387_RS28155	COG4196	transglutaminase domain protein
KM387_RS28160	COG0671	phosphoesterase, PA-phosphatase related
KM387_RS28175	COG1215	transferase activity, transferring glycosyl groups
KM387_RS28180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM387_RS28185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM387_RS28350	COG2002	toxin-antitoxin pair type II binding
KM387_RS28360	COG4974	Belongs to the 'phage' integrase family
KM387_RS28420	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM387_RS28430	COG4974	Belongs to the 'phage' integrase family
KM387_RS28455	COG0457	Tetratricopeptide repeat
KM387_RS28655	COG0791	NLP P60 protein
KM387_RS28655	COG0741	lytic transglycosylase activity
KM387_RS28775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM387_RS28785	COG4166	transmembrane transport
KM387_RS28830	COG1280	lysine exporter protein (LysE YggA)
KM387_RS28865	COG0681	Belongs to the peptidase S26 family
KM387_RS28940	COG1309	transcriptional regulator
KM387_RS28945	COG1683	Conserved Protein
KM387_RS28990	COG1192	Involved in chromosome partitioning