locus-tag	class	description
BF25_RS00215	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF25_RS00245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF25_RS00505	COG1674	ftsk spoiiie
BF25_RS00780	COG0662	Cupin 2, conserved barrel domain protein
BF25_RS00820	COG4109	DRTGG domain
BF25_RS00850	COG0587	DNA-directed DNA polymerase activity
BF25_RS00855	COG0587	DNA-directed DNA polymerase activity
BF25_RS01335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF25_RS01340	COG4848	Belongs to the UPF0354 family
BF25_RS01345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF25_RS01355	COG1674	ftsk spoiiie
BF25_RS01370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS01390	COG2309	aminopeptidase activity
BF25_RS01400	COG3118	belongs to the thioredoxin family
BF25_RS01405	COG4851	CamS sex pheromone cAM373 precursor
BF25_RS01415	COG1609	Transcriptional regulator
BF25_RS01450	COG0666	response to abiotic stimulus
BF25_RS01460	COG0745	RESPONSE REGULATOR receiver
BF25_RS01470	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF25_RS01475	COG0517	IMP dehydrogenase activity
BF25_RS01480	COG0454	-acetyltransferase
BF25_RS01485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF25_RS01495	COG1595	DNA-templated transcription, initiation
BF25_RS01525	COG0626	cystathionine gamma-synthase activity
BF25_RS01530	COG1956	GAF domain-containing protein
BF25_RS01540	COG0697	spore germination
BF25_RS01545	COG0583	DNA-binding transcription factor activity
BF25_RS01555	COG1104	cysteine desulfurase activity
BF25_RS01570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF25_RS01580	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF25_RS01595	COG3874	Sporulation protein YtfJ
BF25_RS01600	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF25_RS01605	COG0827	DNA restriction-modification system
BF25_RS01610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF25_RS01630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS01670	COG0589	response to stress
BF25_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS01690	COG1476	TRANSCRIPTIONal
BF25_RS01700	COG0662	Cupin 2, conserved barrel domain protein
BF25_RS01705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS01740	COG0006	proline dipeptidase activity
BF25_RS01755	COG4109	DRTGG domain
BF25_RS01775	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF25_RS01790	COG0587	DNA-directed DNA polymerase activity
BF25_RS01795	COG0281	malic enzyme
BF25_RS01800	COG1725	Transcriptional regulator
BF25_RS01825	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF25_RS01830	COG0628	permease
BF25_RS01845	COG0372	Belongs to the citrate synthase family
BF25_RS01850	COG0538	isocitrate dehydrogenase activity
BF25_RS01870	COG0745	RESPONSE REGULATOR receiver
BF25_RS01875	COG5002	protein histidine kinase activity
BF25_RS01880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF25_RS01880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF25_RS01890	COG1971	Probably functions as a manganese efflux pump
BF25_RS01895	COG0237	dephospho-CoA kinase activity
BF25_RS01900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF25_RS01905	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF25_RS01915	COG3611	Membrane attachment protein
BF25_RS01920	COG1484	DNA-dependent DNA replication
BF25_RS01930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF25_RS01955	COG1363	Peptidase, m42
BF25_RS01960	COG1309	transcriptional regulator
BF25_RS01965	COG1566	PFAM secretion protein HlyD family protein
BF25_RS01970	COG2814	Major facilitator Superfamily
BF25_RS01995	COG1418	mRNA catabolic process
BF25_RS02005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF25_RS02050	COG1286	toxin biosynthetic process
BF25_RS02055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF25_RS02055	COG1796	DNA polymerase
BF25_RS02070	COG1187	pseudouridine synthase activity
BF25_RS02075	COG1114	Component of the transport system for branched-chain amino acids
BF25_RS02080	COG5386	Cell surface protein
BF25_RS02090	COG5386	Cell surface protein
BF25_RS02105	COG1120	ATPase activity
BF25_RS02110	COG4509	Sortase family
BF25_RS02125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF25_RS02130	COG4895	conserved protein (DUF2196)
BF25_RS02140	COG0745	RESPONSE REGULATOR receiver
BF25_RS02145	COG2205	protein histidine kinase activity
BF25_RS02150	COG1131	(ABC) transporter
BF25_RS02180	COG2318	DinB family
BF25_RS02200	COG0318	PFAM AMP-dependent synthetase and ligase
BF25_RS02205	COG1309	transcriptional regulator
BF25_RS02210	COG1024	Enoyl-CoA hydratase
BF25_RS02215	COG2086	electron transfer activity
BF25_RS02220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF25_RS02225	COG3118	belongs to the thioredoxin family
BF25_RS02235	COG1719	4-vinyl reductase, 4VR
BF25_RS02240	COG2009	succinate dehydrogenase
BF25_RS02245	COG1053	succinate dehydrogenase
BF25_RS02250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF25_RS02255	COG0824	Thioesterase
BF25_RS02260	COG1876	peptidase activity
BF25_RS02265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF25_RS02275	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF25_RS02280	COG4152	abc transporter atp-binding protein
BF25_RS02285	COG1668	transmembrane transport
BF25_RS02290	COG1959	2 iron, 2 sulfur cluster binding
BF25_RS02300	COG0697	spore germination
BF25_RS02305	COG1396	sequence-specific DNA binding
BF25_RS02310	COG1983	PspC domain protein
BF25_RS02325	COG3279	Response regulator of the LytR AlgR family
BF25_RS02335	COG4608	Belongs to the ABC transporter superfamily
BF25_RS02340	COG0444	Belongs to the ABC transporter superfamily
BF25_RS02350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF25_RS02360	COG0402	S-adenosylhomocysteine deaminase activity
BF25_RS02365	COG0402	S-adenosylhomocysteine deaminase activity
BF25_RS02375	COG2233	PERMEase
BF25_RS02380	COG2197	response regulator
BF25_RS02395	COG1309	transcriptional regulator
BF25_RS02415	COG5401	PFAM Sporulation and spore germination
BF25_RS02430	COG0622	Phosphoesterase
BF25_RS02480	COG1067	ATP-dependent peptidase activity
BF25_RS02480	COG0470	DNA polymerase III
BF25_RS02495	COG1764	response to oxidative stress
BF25_RS02500	COG1846	Transcriptional regulator
BF25_RS02510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF25_RS02520	COG1587	Uroporphyrinogen-III synthase
BF25_RS02525	COG0113	porphobilinogen synthase activity
BF25_RS02535	COG1388	LysM domain
BF25_RS02545	COG0525	valine-tRNA ligase activity
BF25_RS02550	COG0285	dihydrofolate synthase activity
BF25_RS02570	COG1077	Cell shape determining protein MreB Mrl
BF25_RS02590	COG2894	cell division
BF25_RS02595	COG0739	heme binding
BF25_RS02600	COG1994	Peptidase M50
BF25_RS02605	COG1530	ribonuclease E activity
BF25_RS02615	COG2868	ribosomal protein
BF25_RS02625	COG3290	protein histidine kinase activity
BF25_RS02630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF25_RS02635	COG0745	RESPONSE REGULATOR receiver
BF25_RS02650	COG1136	(ABC) transporter
BF25_RS02655	COG0577	efflux transmembrane transporter activity
BF25_RS02660	COG0577	efflux transmembrane transporter activity
BF25_RS02665	COG0077	Prephenate dehydratase
BF25_RS02670	COG2258	MOSC domain
BF25_RS02675	COG1827	regulation of RNA biosynthetic process
BF25_RS02680	COG1104	cysteine desulfurase activity
BF25_RS02685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF25_RS02690	COG0157	Belongs to the NadC ModD family
BF25_RS02715	COG0640	Transcriptional regulator
BF25_RS02720	COG0697	spore germination
BF25_RS02725	COG0697	spore germination
BF25_RS02735	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF25_RS02765	COG1862	Preprotein translocase
BF25_RS02775	COG2323	membrane
BF25_RS02780	COG2244	polysaccharide biosynthetic process
BF25_RS02790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF25_RS02790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF25_RS02795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF25_RS02800	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF25_RS02800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF25_RS02810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF25_RS02835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF25_RS02845	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF25_RS02850	COG1959	2 iron, 2 sulfur cluster binding
BF25_RS02855	COG1104	cysteine desulfurase activity
BF25_RS02860	COG0482	sulfurtransferase activity
BF25_RS02870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF25_RS02890	COG0628	permease
BF25_RS02900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF25_RS02920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF25_RS02925	COG4122	O-methyltransferase activity
BF25_RS02930	COG0826	peptidase U32
BF25_RS02935	COG0826	peptidase U32
BF25_RS02950	COG0768	penicillin binding
BF25_RS02975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF25_RS02980	COG0626	cystathionine gamma-synthase activity
BF25_RS02985	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS02985	COG1454	alcohol dehydrogenase
BF25_RS02995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS03035	COG2259	Doxx family
BF25_RS03055	COG3186	Phenylalanine-4-hydroxylase
BF25_RS03060	COG1404	Belongs to the peptidase S8 family
BF25_RS03095	COG2267	carboxylic ester hydrolase activity
BF25_RS03105	COG1785	Belongs to the alkaline phosphatase family
BF25_RS03115	COG2357	RelA SpoT domain protein
BF25_RS03120	COG0778	Nitroreductase
BF25_RS03130	COG1595	DNA-templated transcription, initiation
BF25_RS03155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF25_RS03160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF25_RS03170	COG1534	Rna-binding protein
BF25_RS03180	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF25_RS03185	COG0799	negative regulation of ribosome biogenesis
BF25_RS03190	COG2226	methyltransferase
BF25_RS03195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF25_RS03200	COG1555	photosystem II stabilization
BF25_RS03200	COG1596	polysaccharide export
BF25_RS03205	COG2131	deaminase
BF25_RS03210	COG2333	competence protein COMEC
BF25_RS03210	COG0658	competence protein
BF25_RS03220	COG1466	dna polymerase III delta subunit
BF25_RS03245	COG1733	regulation of RNA biosynthetic process
BF25_RS03250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF25_RS03280	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF25_RS03285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF25_RS03290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BF25_RS03295	COG1610	YqeY-like protein
BF25_RS03315	COG1702	phosphate starvation-inducible protein PhoH
BF25_RS03320	COG1480	7TM receptor with intracellular HD hydrolase
BF25_RS03330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF25_RS03335	COG0295	cytidine deaminase activity
BF25_RS03340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF25_RS03355	COG0517	IMP dehydrogenase activity
BF25_RS03375	COG0358	DNA primase activity
BF25_RS03380	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF25_RS03385	COG2010	Cytochrome c
BF25_RS03390	COG2384	SAM-dependent methyltransferase
BF25_RS03395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF25_RS03425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS03430	COG1121	(ABC) transporter
BF25_RS03435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF25_RS03440	COG0735	belongs to the Fur family
BF25_RS03465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF25_RS03470	COG0477	Major facilitator Superfamily
BF25_RS03475	COG0768	penicillin binding
BF25_RS03480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF25_RS03485	COG0573	inorganic phosphate transmembrane transporter activity
BF25_RS03490	COG0581	inorganic phosphate transmembrane transporter activity
BF25_RS03500	COG0704	Plays a role in the regulation of phosphate uptake
BF25_RS03505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF25_RS03510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF25_RS03515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF25_RS03520	COG4483	Protein conserved in bacteria
BF25_RS03525	COG1940	carbohydrate kinase activity
BF25_RS03535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS03560	COG0626	cystathionine gamma-synthase activity
BF25_RS03565	COG0626	cystathionine gamma-synthase activity
BF25_RS03575	COG0646	methionine synthase
BF25_RS03575	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF25_RS03580	COG0646	methionine synthase
BF25_RS03580	COG1410	methionine synthase
BF25_RS03585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF25_RS03635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF25_RS03640	COG1459	type II secretion system
BF25_RS03650	COG4970	Tfp pilus assembly protein FimT
BF25_RS03705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF25_RS03735	COG1725	Transcriptional regulator
BF25_RS03740	COG1131	(ABC) transporter
BF25_RS03780	COG2076	Multidrug Resistance protein
BF25_RS03785	COG2076	Multidrug Resistance protein
BF25_RS03795	COG1609	Transcriptional regulator
BF25_RS03800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF25_RS03805	COG0095	Lipoate-protein ligase
BF25_RS03825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF25_RS03835	COG3872	metal-dependent enzyme
BF25_RS03850	COG0006	proline dipeptidase activity
BF25_RS03875	COG3854	ATPases associated with a variety of cellular activities
BF25_RS03920	COG0511	ligase activity, forming carbon-carbon bonds
BF25_RS03925	COG0439	Biotin carboxylase
BF25_RS03930	COG1302	Protein conserved in bacteria
BF25_RS03955	COG0142	geranyltranstransferase activity
BF25_RS03965	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF25_RS03975	COG0497	DNA recombination
BF25_RS03980	COG0750	zinc metalloprotease
BF25_RS03985	COG0745	RESPONSE REGULATOR receiver
BF25_RS03995	COG3093	addiction module antidote protein HigA
BF25_RS04000	COG0584	glycerophosphoryl diester phosphodiesterase
BF25_RS04010	COG3290	protein histidine kinase activity
BF25_RS04010	COG3829	transcription factor binding
BF25_RS04020	COG0280	phosphate acetyltransferase
BF25_RS04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF25_RS04040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF25_RS04045	COG0022	dehydrogenase e1 component
BF25_RS04050	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF25_RS04060	COG0772	Belongs to the SEDS family
BF25_RS04065	COG2816	NAD+ diphosphatase activity
BF25_RS04085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF25_RS04090	COG0765	amino acid transport
BF25_RS04095	COG1126	abc transporter atp-binding protein
BF25_RS04100	COG4129	membrane
BF25_RS04105	COG1376	ErfK ybiS ycfS ynhG family protein
BF25_RS04120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS04125	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF25_RS04135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF25_RS04155	COG1760	l-serine dehydratase
BF25_RS04160	COG1760	l-serine dehydratase
BF25_RS04165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF25_RS04180	COG0300	oxidoreductase activity
BF25_RS04195	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF25_RS04205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF25_RS04225	COG1522	sequence-specific DNA binding
BF25_RS04235	COG0737	Belongs to the 5'-nucleotidase family
BF25_RS04240	COG1757	Na H antiporter
BF25_RS04250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF25_RS04265	COG2226	methyltransferase
BF25_RS04265	COG1073	alpha beta
BF25_RS04270	COG4106	trans-aconitate 2-methyltransferase activity
BF25_RS04295	COG0307	riboflavin synthase, alpha
BF25_RS04300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF25_RS04300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF25_RS04315	COG1073	alpha beta
BF25_RS04320	COG0456	acetyltransferase
BF25_RS04325	COG1609	Transcriptional regulator
BF25_RS04330	COG2056	Na+-H+ antiporter family
BF25_RS04335	COG0596	Alpha beta hydrolase
BF25_RS04345	COG0737	Belongs to the 5'-nucleotidase family
BF25_RS04345	COG1525	nuclease
BF25_RS04345	COG4085	toxin activity
BF25_RS04355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF25_RS04355	COG0456	acetyltransferase
BF25_RS04360	COG0656	L-ascorbic acid biosynthetic process
BF25_RS04365	COG0667	Aldo Keto reductase
BF25_RS04385	COG1300	Membrane
BF25_RS04390	COG0735	belongs to the Fur family
BF25_RS04400	COG4974	Belongs to the 'phage' integrase family
BF25_RS04425	COG0598	Magnesium transport protein CorA
BF25_RS04440	COG1846	Transcriptional regulator
BF25_RS04460	COG1131	(ABC) transporter
BF25_RS04465	COG1725	Transcriptional regulator
BF25_RS04470	COG1686	Belongs to the peptidase S11 family
BF25_RS04490	COG0733	neurotransmitter:sodium symporter activity
BF25_RS04515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF25_RS04530	COG0697	spore germination
BF25_RS04535	COG0561	phosphatase activity
BF25_RS04540	COG4086	secreted protein
BF25_RS04545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF25_RS04555	COG0456	acetyltransferase
BF25_RS04560	COG1547	Domain of unknown function (DUF309)
BF25_RS04590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF25_RS04600	COG2188	Transcriptional regulator
BF25_RS04610	COG3711	transcriptional antiterminator
BF25_RS04615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF25_RS04615	COG2190	(PTS) system
BF25_RS04615	COG1263	PTS System
BF25_RS04640	COG0778	Nitroreductase
BF25_RS04645	COG2199	diguanylate cyclase activity
BF25_RS04665	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF25_RS04685	COG0436	Aminotransferase
BF25_RS04690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF25_RS04700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BF25_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS04715	COG1695	Transcriptional regulator
BF25_RS04755	COG0183	Belongs to the thiolase family
BF25_RS04795	COG3842	ATPase activity
BF25_RS04800	COG0366	Alpha amylase catalytic
BF25_RS04810	COG2182	Extracellular solute-binding protein
BF25_RS04815	COG1175	transmembrane transport
BF25_RS04820	COG3833	ABC-type maltose transport systems, permease component
BF25_RS04825	COG1609	Transcriptional regulator
BF25_RS04830	COG0436	Aminotransferase
BF25_RS04840	COG2205	protein histidine kinase activity
BF25_RS04850	COG3209	COG3209 Rhs family protein
BF25_RS04875	COG2814	Major facilitator Superfamily
BF25_RS04915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF25_RS04925	COG1408	metallophosphoesterase
BF25_RS04930	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS04935	COG2200	EAL domain
BF25_RS04950	COG4703	Protein of unknown function (DUF1797)
BF25_RS04960	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF25_RS04970	COG0517	IMP dehydrogenase activity
BF25_RS04975	COG0583	DNA-binding transcription factor activity
BF25_RS04995	COG0569	domain protein
BF25_RS05000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF25_RS05010	COG0561	phosphatase activity
BF25_RS05015	COG0242	peptide deformylase activity
BF25_RS05025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF25_RS05030	COG0022	dehydrogenase e1 component
BF25_RS05035	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF25_RS05080	COG1982	Orn Lys Arg decarboxylase major
BF25_RS05100	COG0483	inositol monophosphate 1-phosphatase activity
BF25_RS05110	COG1217	gtp-binding protein TYPA
BF25_RS05125	COG4896	Protein conserved in bacteria
BF25_RS05135	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF25_RS05140	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF25_RS05150	COG0772	Belongs to the SEDS family
BF25_RS05155	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF25_RS05190	COG3336	cytochrome c oxidase
BF25_RS05205	COG2340	Cysteine-rich secretory protein family
BF25_RS05220	COG0406	alpha-ribazole phosphatase activity
BF25_RS05225	COG3679	Belongs to the UPF0342 family
BF25_RS05240	COG0742	ribosomal rna small subunit methyltransferase
BF25_RS05250	COG3314	Sporulation integral membrane protein YlbJ
BF25_RS05255	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF25_RS05260	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF25_RS05270	COG0582	viral genome integration into host DNA
BF25_RS05285	COG1396	sequence-specific DNA binding
BF25_RS05295	COG1396	sequence-specific DNA binding
BF25_RS05325	COG1484	DNA-dependent DNA replication
BF25_RS05350	COG1191	sigma factor activity
BF25_RS05360	COG0756	dUTP diphosphatase activity
BF25_RS05430	COG0582	viral genome integration into host DNA
BF25_RS05455	COG1802	Transcriptional regulator
BF25_RS05455	COG4626	Terminase
BF25_RS05550	COG4824	toxin secretion phage lysis holin
BF25_RS05600	COG1399	metal-binding, possibly nucleic acid-binding protein
BF25_RS05605	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BF25_RS05620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF25_RS05635	COG4839	cell division protein FtsL
BF25_RS05640	COG0768	penicillin binding
BF25_RS05645	COG0768	penicillin binding
BF25_RS05650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF25_RS05665	COG0772	Belongs to the SEDS family
BF25_RS05675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF25_RS05680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF25_RS05685	COG0849	cell division
BF25_RS05690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF25_RS05700	COG1191	sigma factor activity
BF25_RS05705	COG1191	sigma factor activity
BF25_RS05710	COG1873	PFAM PRC-barrel domain
BF25_RS05715	COG1496	oxidoreductase activity
BF25_RS05720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF25_RS05730	COG0762	integral membrane protein
BF25_RS05735	COG2302	S4 RNA-binding domain
BF25_RS05740	COG3599	regulation of cell shape
BF25_RS05760	COG0564	pseudouridine synthase activity
BF25_RS05825	COG3069	C4-dicarboxylate transmembrane transporter activity
BF25_RS05840	COG0006	proline dipeptidase activity
BF25_RS05850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF25_RS05855	COG1561	YicC-like family, N-terminal region
BF25_RS05875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF25_RS05880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF25_RS05885	COG0242	peptide deformylase activity
BF25_RS05895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF25_RS05895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF25_RS05905	COG0631	protein serine/threonine phosphatase activity
BF25_RS05910	COG0515	serine threonine protein kinase
BF25_RS05910	COG2815	serine threonine protein kinase
BF25_RS05915	COG1162	GTPase activity
BF25_RS05920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF25_RS05925	COG1564	THIamine pyrophosphokinase
BF25_RS05940	COG1302	Protein conserved in bacteria
BF25_RS05945	COG1461	Dihydroxyacetone kinase
BF25_RS05950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF25_RS05965	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF25_RS05970	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS05975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF25_RS05985	COG1196	nuclear chromosome segregation
BF25_RS05990	COG0552	protein localization to endoplasmic reticulum
BF25_RS06000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF25_RS06010	COG1837	Belongs to the UPF0109 family
BF25_RS06050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF25_RS06060	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF25_RS06070	COG4974	Belongs to the 'phage' integrase family
BF25_RS06100	COG0528	UMP kinase activity
BF25_RS06110	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF25_RS06115	COG4589	Belongs to the CDS family
BF25_RS06125	COG0750	zinc metalloprotease
BF25_RS06145	COG0195	Participates in both transcription termination and antitermination
BF25_RS06150	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF25_RS06155	COG1358	cellular component organization or biogenesis
BF25_RS06165	COG1550	Protein conserved in bacteria
BF25_RS06175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF25_RS06180	COG0196	riboflavin kinase activity
BF25_RS06195	COG0726	polysaccharide deacetylase
BF25_RS06200	COG0612	Peptidase, M16
BF25_RS06205	COG1873	PFAM PRC-barrel domain
BF25_RS06210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF25_RS06215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF25_RS06220	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF25_RS06225	COG0527	aspartate kinase activity
BF25_RS06240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF25_RS06245	COG0740	serine-type endopeptidase activity
BF25_RS06255	COG1674	ftsk spoiiie
BF25_RS06260	COG2188	Transcriptional regulator
BF25_RS06265	COG1744	ABC transporter substrate-binding protein PnrA-like
BF25_RS06270	COG3845	ABC transporter
BF25_RS06275	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF25_RS06280	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF25_RS06290	COG0612	Peptidase, M16
BF25_RS06295	COG0612	Peptidase, M16
BF25_RS06300	COG0300	oxidoreductase activity
BF25_RS06315	COG1426	Protein conserved in bacteria
BF25_RS06320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF25_RS06345	COG1692	metallophosphoesterase
BF25_RS06350	COG2359	stage V sporulation protein S
BF25_RS06360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF25_RS06360	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF25_RS06365	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF25_RS06370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF25_RS06375	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF25_RS06395	COG1131	(ABC) transporter
BF25_RS06420	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF25_RS06430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF25_RS06435	COG1368	sulfuric ester hydrolase activity
BF25_RS06440	COG0562	UDP-galactopyranose mutase
BF25_RS06445	COG3773	Cell wall hydrolase
BF25_RS06450	COG1404	Belongs to the peptidase S8 family
BF25_RS06465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF25_RS06470	COG0596	Alpha beta hydrolase
BF25_RS06470	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF25_RS06475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS06480	COG1380	Effector of murein hydrolase LrgA
BF25_RS06485	COG1346	cytolysis
BF25_RS06505	COG3300	MHYT domain
BF25_RS06505	COG5001	Diguanylate cyclase
BF25_RS06510	COG0346	lactoylglutathione lyase activity
BF25_RS06515	COG2267	carboxylic ester hydrolase activity
BF25_RS06530	COG2364	Membrane
BF25_RS06540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF25_RS06545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF25_RS06550	COG2169	Transcriptional regulator
BF25_RS06555	COG0708	Exodeoxyribonuclease III
BF25_RS06565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS06570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS06575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS06580	COG1120	ATPase activity
BF25_RS06585	COG2819	hydrolase of the alpha beta superfamily
BF25_RS06595	COG1937	Protein conserved in bacteria
BF25_RS06600	COG2608	mercury ion transmembrane transporter activity
BF25_RS06605	COG2217	Heavy metal translocating P-type atpase
BF25_RS06615	COG2116	formate transmembrane transporter activity
BF25_RS06620	COG1408	metallophosphoesterase
BF25_RS06630	COG1113	amino acid transport
BF25_RS06645	COG2322	membrane
BF25_RS06655	COG1349	DNA-binding transcription factor activity
BF25_RS06660	COG1105	Belongs to the carbohydrate kinase PfkB family
BF25_RS06665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF25_RS06665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF25_RS06665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF25_RS06670	COG3584	3D domain protein
BF25_RS06670	COG1388	LysM domain
BF25_RS06700	COG0464	growth
BF25_RS06705	COG2860	membrane
BF25_RS06715	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF25_RS06720	COG0789	Transcriptional regulator
BF25_RS06725	COG0174	glutamine synthetase
BF25_RS06750	COG1396	sequence-specific DNA binding
BF25_RS06830	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF25_RS06875	COG1595	DNA-templated transcription, initiation
BF25_RS07035	COG4824	toxin secretion phage lysis holin
BF25_RS07040	COG3409	Peptidoglycan-binding domain 1 protein
BF25_RS07040	COG1388	LysM domain
BF25_RS07040	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF25_RS07075	COG1695	Transcriptional regulator
BF25_RS07095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF25_RS07120	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF25_RS07125	COG3639	organic phosphonate transmembrane transporter activity
BF25_RS07160	COG1132	(ABC) transporter
BF25_RS07165	COG1132	(ABC) transporter
BF25_RS07180	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF25_RS07180	COG3409	Peptidoglycan-binding domain 1 protein
BF25_RS07205	COG1346	cytolysis
BF25_RS07210	COG1380	Effector of murein hydrolase LrgA
BF25_RS07215	COG0583	DNA-binding transcription factor activity
BF25_RS07225	COG0785	Cytochrome C biogenesis protein
BF25_RS07230	COG4846	Membrane protein involved in cytochrome C biogenesis
BF25_RS07285	COG2226	methyltransferase
BF25_RS07310	COG0010	Belongs to the arginase family
BF25_RS07315	COG1329	Transcriptional regulator
BF25_RS07320	COG1902	pentaerythritol trinitrate reductase activity
BF25_RS07325	COG0069	glutamate synthase activity
BF25_RS07330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF25_RS07335	COG0346	lactoylglutathione lyase activity
BF25_RS07340	COG0400	carboxylic ester hydrolase activity
BF25_RS07345	COG5002	protein histidine kinase activity
BF25_RS07355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS07400	COG0318	PFAM AMP-dependent synthetase and ligase
BF25_RS07405	COG1268	BioY protein
BF25_RS07410	COG0318	PFAM AMP-dependent synthetase and ligase
BF25_RS07415	COG0183	Belongs to the thiolase family
BF25_RS07430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF25_RS07440	COG2211	Major facilitator Superfamily
BF25_RS07470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF25_RS07475	COG2274	protein secretion by the type I secretion system
BF25_RS07485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF25_RS07515	COG0824	Thioesterase
BF25_RS07520	COG4841	protein insertion into membrane
BF25_RS07525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF25_RS07540	COG0745	RESPONSE REGULATOR receiver
BF25_RS07545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF25_RS07550	COG1832	CoA-binding protein
BF25_RS07560	COG0187	DNA topoisomerase II activity
BF25_RS07565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF25_RS07570	COG0673	inositol 2-dehydrogenase activity
BF25_RS07580	COG1131	(ABC) transporter
BF25_RS07605	COG1595	DNA-templated transcription, initiation
BF25_RS07615	COG1316	TRANSCRIPTIONal
BF25_RS07625	COG4166	transmembrane transport
BF25_RS07630	COG4166	transmembrane transport
BF25_RS07635	COG4166	transmembrane transport
BF25_RS07640	COG2226	methyltransferase
BF25_RS07680	COG0697	spore germination
BF25_RS07690	COG3383	formate dehydrogenase (NAD+) activity
BF25_RS07695	COG2427	Protein of unknown function (DUF1641)
BF25_RS07700	COG5609	conserved protein (DUF2294)
BF25_RS07705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF25_RS07715	COG2116	formate transmembrane transporter activity
BF25_RS07720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF25_RS07725	COG0303	'Molybdopterin
BF25_RS07730	COG0314	molybdopterin synthase activity
BF25_RS07740	COG0489	protein tyrosine kinase activity
BF25_RS07755	COG3326	Membrane
BF25_RS07760	COG2962	Rard protein
BF25_RS07765	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF25_RS07770	COG1657	PFAM Prenyltransferase squalene oxidase
BF25_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS07785	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS07795	COG4145	pantothenate transmembrane transporter activity
BF25_RS07810	COG0165	Argininosuccinate lyase
BF25_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS07850	COG0716	FMN binding
BF25_RS07890	COG2720	vancomycin resistance protein
BF25_RS07895	COG2514	catechol 2,3-dioxygenase activity
BF25_RS07905	COG1285	pathogenesis
BF25_RS07915	COG1024	Enoyl-CoA hydratase
BF25_RS07920	COG1216	Glycosyl transferase, family 2
BF25_RS07950	COG0277	FAD linked oxidase domain protein
BF25_RS07955	COG0385	Bile acid
BF25_RS07965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF25_RS07970	COG2808	Putative FMN-binding domain
BF25_RS07990	COG0604	alcohol dehydrogenase
BF25_RS07995	COG0640	Transcriptional regulator
BF25_RS08020	COG0584	glycerophosphoryl diester phosphodiesterase
BF25_RS08050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF25_RS08055	COG1164	Oligoendopeptidase f
BF25_RS08075	COG1193	negative regulation of DNA recombination
BF25_RS08095	COG0583	DNA-binding transcription factor activity
BF25_RS08125	COG0384	phenazine biosynthesis protein PhzF
BF25_RS08130	COG3739	integral membrane protein
BF25_RS08135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS08140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS08150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS08170	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF25_RS08175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF25_RS08210	COG2814	Major facilitator Superfamily
BF25_RS08215	COG1113	amino acid transport
BF25_RS08255	COG2072	flavoprotein involved in K transport
BF25_RS08290	COG3409	Peptidoglycan-binding domain 1 protein
BF25_RS08290	COG3757	hydrolase, family 25
BF25_RS08295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS08305	COG1151	hydroxylamine reductase activity
BF25_RS08330	COG3152	Membrane
BF25_RS08350	COG1309	transcriptional regulator
BF25_RS08365	COG1191	sigma factor activity
BF25_RS08400	COG1733	regulation of RNA biosynthetic process
BF25_RS08410	COG0318	PFAM AMP-dependent synthetase and ligase
BF25_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS08430	COG0384	phenazine biosynthesis protein PhzF
BF25_RS08450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS08465	COG1733	regulation of RNA biosynthetic process
BF25_RS08470	COG1733	regulation of RNA biosynthetic process
BF25_RS08475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF25_RS08485	COG2188	Transcriptional regulator
BF25_RS08490	COG1733	regulation of RNA biosynthetic process
BF25_RS08500	COG1393	Belongs to the ArsC family
BF25_RS08525	COG0814	amino acid
BF25_RS08530	COG0346	lactoylglutathione lyase activity
BF25_RS08545	COG2814	Major facilitator Superfamily
BF25_RS08550	COG0656	L-ascorbic acid biosynthetic process
BF25_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS08585	COG0604	alcohol dehydrogenase
BF25_RS08585	COG3321	synthase
BF25_RS08595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF25_RS08600	COG0604	alcohol dehydrogenase
BF25_RS08605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF25_RS08610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF25_RS08620	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF25_RS08625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF25_RS08635	COG1070	Carbohydrate kinase
BF25_RS08640	COG2706	6-phosphogluconolactonase activity
BF25_RS08645	COG3813	Protein conserved in bacteria
BF25_RS08650	COG1357	PFAM Pentapeptide repeats (8 copies)
BF25_RS08655	COG0697	spore germination
BF25_RS08660	COG0789	Transcriptional regulator
BF25_RS08665	COG1253	flavin adenine dinucleotide binding
BF25_RS08695	COG0477	Major facilitator Superfamily
BF25_RS08705	COG2226	methyltransferase
BF25_RS08725	COG0628	permease
BF25_RS08730	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF25_RS08740	COG1136	(ABC) transporter
BF25_RS08740	COG0577	efflux transmembrane transporter activity
BF25_RS08755	COG0110	maltose O-acetyltransferase activity
BF25_RS08760	COG0738	Major facilitator superfamily
BF25_RS08765	COG1940	carbohydrate kinase activity
BF25_RS08770	COG0346	lactoylglutathione lyase activity
BF25_RS08795	COG2365	Tyrosine phosphatase family
BF25_RS08805	COG1011	Hydrolase
BF25_RS08830	COG1131	(ABC) transporter
BF25_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS08860	COG0778	Nitroreductase
BF25_RS08865	COG1733	regulation of RNA biosynthetic process
BF25_RS08880	COG0124	histidyl-tRNA synthetase
BF25_RS08885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF25_RS08890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF25_RS08895	COG3620	sequence-specific DNA binding
BF25_RS08910	COG2356	endonuclease I
BF25_RS08915	COG1288	antiporter activity
BF25_RS08920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF25_RS08935	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF25_RS08940	COG1122	ATPase activity
BF25_RS08970	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF25_RS08980	COG2031	fatty acid transporter
BF25_RS08995	COG1309	transcriptional regulator
BF25_RS09000	COG2076	Multidrug Resistance protein
BF25_RS09020	COG1131	(ABC) transporter
BF25_RS09025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF25_RS09040	COG2814	Major facilitator Superfamily
BF25_RS09045	COG1846	Transcriptional regulator
BF25_RS09055	COG0477	Major facilitator Superfamily
BF25_RS09110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS09110	COG2207	Transcriptional regulator
BF25_RS09120	COG0662	Cupin 2, conserved barrel domain protein
BF25_RS09135	COG1595	DNA-templated transcription, initiation
BF25_RS09155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF25_RS09170	COG0531	amino acid
BF25_RS09175	COG1522	sequence-specific DNA binding
BF25_RS09180	COG1335	isochorismatase
BF25_RS09190	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF25_RS09195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF25_RS09205	COG1760	l-serine dehydratase
BF25_RS09210	COG1760	l-serine dehydratase
BF25_RS09215	COG0814	amino acid
BF25_RS09230	COG1309	transcriptional regulator
BF25_RS09235	COG2814	Major facilitator Superfamily
BF25_RS09240	COG2184	nucleotidyltransferase activity
BF25_RS09250	COG0534	Mate efflux family protein
BF25_RS09280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF25_RS09300	COG0457	Tetratricopeptide repeat
BF25_RS09305	COG1609	Transcriptional regulator
BF25_RS09315	COG0561	phosphatase activity
BF25_RS09320	COG0673	inositol 2-dehydrogenase activity
BF25_RS09325	COG0738	Major facilitator superfamily
BF25_RS09350	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF25_RS09360	COG0583	DNA-binding transcription factor activity
BF25_RS09370	COG1139	Iron-sulfur cluster binding protein
BF25_RS09375	COG1556	Lactate utilization protein
BF25_RS09380	COG2271	Major facilitator Superfamily
BF25_RS09385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS09390	COG2808	Putative FMN-binding domain
BF25_RS09395	COG0456	acetyltransferase
BF25_RS09400	COG1846	Transcriptional regulator
BF25_RS09405	COG2364	Membrane
BF25_RS09415	COG5002	protein histidine kinase activity
BF25_RS09415	COG3850	Histidine kinase
BF25_RS09435	COG0577	efflux transmembrane transporter activity
BF25_RS09440	COG1136	(ABC) transporter
BF25_RS09455	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF25_RS09460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF25_RS09470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF25_RS09475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS09490	COG1476	TRANSCRIPTIONal
BF25_RS09515	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF25_RS09545	COG5002	protein histidine kinase activity
BF25_RS09545	COG3850	Histidine kinase
BF25_RS09550	COG0745	RESPONSE REGULATOR receiver
BF25_RS09575	COG2814	Major facilitator Superfamily
BF25_RS09620	COG2169	Transcriptional regulator
BF25_RS09645	COG0346	lactoylglutathione lyase activity
BF25_RS09660	COG1522	sequence-specific DNA binding
BF25_RS09675	COG0443	Heat shock 70 kDa protein
BF25_RS09690	COG0640	Transcriptional regulator
BF25_RS09695	COG0346	lactoylglutathione lyase activity
BF25_RS09700	COG0798	PFAM Bile acid sodium symporter
BF25_RS09730	COG1121	(ABC) transporter
BF25_RS09735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF25_RS09740	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF25_RS09745	COG2267	carboxylic ester hydrolase activity
BF25_RS09750	COG1575	Belongs to the MenA family. Type 1 subfamily
BF25_RS09760	COG5609	conserved protein (DUF2294)
BF25_RS09765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF25_RS09775	COG0288	reversible hydration of carbon dioxide
BF25_RS09780	COG0415	Belongs to the DNA photolyase family
BF25_RS09825	COG0583	DNA-binding transcription factor activity
BF25_RS09850	COG1335	isochorismatase
BF25_RS09855	COG2267	carboxylic ester hydrolase activity
BF25_RS09860	COG0753	catalase activity
BF25_RS09865	COG0737	Belongs to the 5'-nucleotidase family
BF25_RS09895	COG2066	Belongs to the glutaminase family
BF25_RS09905	COG0784	Response regulator, receiver
BF25_RS09910	COG0697	spore germination
BF25_RS09935	COG0281	malic enzyme
BF25_RS09945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF25_RS09950	COG1114	Component of the transport system for branched-chain amino acids
BF25_RS09955	COG0531	amino acid
BF25_RS09960	COG0322	excinuclease ABC activity
BF25_RS09970	COG1396	sequence-specific DNA binding
BF25_RS09975	COG0252	asparaginase activity
BF25_RS09980	COG1027	Aspartate ammonia-lyase
BF25_RS09995	COG1063	alcohol dehydrogenase
BF25_RS10030	COG1280	lysine exporter protein (LysE YggA)
BF25_RS10035	COG3403	YqcI/YcgG family
BF25_RS10040	COG5577	PFAM Coat F domain
BF25_RS10055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS10060	COG3848	Pyruvate phosphate dikinase
BF25_RS10060	COG0574	Belongs to the PEP-utilizing enzyme family
BF25_RS10075	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF25_RS10090	COG3314	Sporulation integral membrane protein YlbJ
BF25_RS10110	COG1960	acyl-CoA dehydrogenase activity
BF25_RS10120	COG0640	Transcriptional regulator
BF25_RS10125	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF25_RS10140	COG1414	Transcriptional regulator
BF25_RS10145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF25_RS10185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF25_RS10235	COG4335	DNA alkylation repair
BF25_RS10245	COG0833	amino acid
BF25_RS10255	COG0730	response to heat
BF25_RS10285	COG0596	Alpha beta hydrolase
BF25_RS10290	COG0745	RESPONSE REGULATOR receiver
BF25_RS10295	COG0642	Histidine kinase
BF25_RS10315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS10335	COG0456	acetyltransferase
BF25_RS10340	COG2207	Transcriptional regulator
BF25_RS10365	COG0577	efflux transmembrane transporter activity
BF25_RS10365	COG1136	(ABC) transporter
BF25_RS10375	COG1725	Transcriptional regulator
BF25_RS10410	COG1846	Transcriptional regulator
BF25_RS10415	COG0778	Nitroreductase
BF25_RS10425	COG0714	Associated with various cellular activities
BF25_RS10450	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF25_RS10460	COG0753	catalase activity
BF25_RS10465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF25_RS10475	COG0463	Glycosyl transferase, family 2
BF25_RS10500	COG0463	Glycosyl transferase, family 2
BF25_RS10525	COG0714	Associated with various cellular activities
BF25_RS10545	COG0346	lactoylglutathione lyase activity
BF25_RS10550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS10560	COG3279	Response regulator of the LytR AlgR family
BF25_RS10570	COG4377	Putative membrane peptidase family (DUF2324)
BF25_RS10585	COG3655	Transcriptional regulator
BF25_RS10595	COG1785	Belongs to the alkaline phosphatase family
BF25_RS10600	COG3239	Fatty acid desaturase
BF25_RS10605	COG1690	Belongs to the RtcB family
BF25_RS10610	COG0833	amino acid
BF25_RS10615	COG1414	Transcriptional regulator
BF25_RS10620	COG4187	Peptidase family M20/M25/M40
BF25_RS10625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF25_RS10630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF25_RS10640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS10660	COG2329	Antibiotic biosynthesis monooxygenase
BF25_RS10695	COG2390	Transcriptional regulator
BF25_RS10705	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF25_RS10715	COG1879	ABC-type sugar transport system periplasmic component
BF25_RS10740	COG1595	DNA-templated transcription, initiation
BF25_RS10750	COG1388	LysM domain
BF25_RS10750	COG3584	3D domain protein
BF25_RS10785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF25_RS10785	COG1605	Chorismate mutase
BF25_RS10790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF25_RS10795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF25_RS10800	COG0287	Prephenate dehydrogenase
BF25_RS10815	COG1309	transcriptional regulator
BF25_RS10820	COG2409	Drug exporters of the RND superfamily
BF25_RS10820	COG1033	growth of symbiont in host cell
BF25_RS10840	COG0488	(ABC) transporter
BF25_RS10845	COG1368	sulfuric ester hydrolase activity
BF25_RS10850	COG0861	Integral membrane protein TerC family
BF25_RS10870	COG4912	Dna alkylation repair
BF25_RS10890	COG2318	DinB family
BF25_RS10895	COG0697	spore germination
BF25_RS10920	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF25_RS10940	COG2816	NAD+ diphosphatase activity
BF25_RS10960	COG1116	anion transmembrane transporter activity
BF25_RS10965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF25_RS10970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF25_RS10975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF25_RS10990	COG0628	permease
BF25_RS11065	COG5146	pantothenate kinase activity
BF25_RS11070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF25_RS11075	COG0436	Aminotransferase
BF25_RS11110	COG2226	methyltransferase
BF25_RS11125	COG2261	transglycosylase associated protein
BF25_RS11145	COG2814	Major facilitator Superfamily
BF25_RS11145	COG0477	Major facilitator Superfamily
BF25_RS11150	COG4533	DNA binding
BF25_RS11155	COG0789	Transcriptional regulator
BF25_RS11160	COG1664	Polymer-forming cytoskeletal
BF25_RS11170	COG2814	Major facilitator Superfamily
BF25_RS11190	COG1307	EDD domain protein, DegV family
BF25_RS11195	COG1164	Oligoendopeptidase f
BF25_RS11235	COG5002	protein histidine kinase activity
BF25_RS11240	COG2936	dipeptidyl-peptidase activity
BF25_RS11280	COG4948	Mandelate Racemase Muconate Lactonizing
BF25_RS11290	COG4166	transmembrane transport
BF25_RS11295	COG0519	Catalyzes the synthesis of GMP from XMP
BF25_RS11300	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF25_RS11315	COG0586	Pfam SNARE associated Golgi protein
BF25_RS11355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF25_RS11360	COG3938	Belongs to the proline racemase family
BF25_RS11370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF25_RS11375	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS11380	COG1115	amino acid carrier protein
BF25_RS11385	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF25_RS11395	COG3397	chitin binding
BF25_RS11420	COG4637	Psort location Cytoplasmic, score
BF25_RS11450	COG0514	ATP-dependent DNA helicase (RecQ)
BF25_RS11455	COG2105	PFAM AIG2 family protein
BF25_RS11470	COG3973	AAA domain
BF25_RS11520	COG2333	competence protein COMEC
BF25_RS11520	COG0658	competence protein
BF25_RS11550	COG2205	protein histidine kinase activity
BF25_RS11565	COG3397	chitin binding
BF25_RS11570	COG2153	protein acetylation
BF25_RS11575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF25_RS11600	COG0517	IMP dehydrogenase activity
BF25_RS11600	COG4175	Glycine betaine
BF25_RS11605	COG4176	ABC-type proline glycine betaine transport system permease component
BF25_RS11640	COG0456	acetyltransferase
BF25_RS11640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF25_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS11655	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF25_RS11660	COG0022	dehydrogenase e1 component
BF25_RS11665	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF25_RS11670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF25_RS11685	COG1959	2 iron, 2 sulfur cluster binding
BF25_RS11705	COG1349	DNA-binding transcription factor activity
BF25_RS11725	COG3284	Transcriptional regulator
BF25_RS11755	COG1309	transcriptional regulator
BF25_RS11760	COG3844	kynureninase activity
BF25_RS11765	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF25_RS11770	COG3483	tryptophan 2,3-dioxygenase activity
BF25_RS11790	COG2959	enzyme of heme biosynthesis
BF25_RS11805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS11810	COG4129	membrane
BF25_RS11840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS11845	COG0697	spore germination
BF25_RS11855	COG0201	protein transport
BF25_RS11875	COG3227	Zinc metalloprotease (Elastase)
BF25_RS11880	COG1523	belongs to the glycosyl hydrolase 13 family
BF25_RS11895	COG0076	glutamate decarboxylase activity
BF25_RS11915	COG1011	Hydrolase
BF25_RS11940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF25_RS11980	COG0322	excinuclease ABC activity
BF25_RS11995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF25_RS12050	COG3878	Protein conserved in bacteria
BF25_RS12085	COG1051	belongs to the nudix hydrolase family
BF25_RS12090	COG0592	DNA-directed DNA polymerase activity
BF25_RS12095	COG2816	NAD+ diphosphatase activity
BF25_RS12110	COG2223	nitrite transmembrane transporter activity
BF25_RS12120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF25_RS12145	COG0697	spore germination
BF25_RS12165	COG0584	glycerophosphoryl diester phosphodiesterase
BF25_RS12180	COG2814	Major facilitator Superfamily
BF25_RS12210	COG0693	protein deglycase activity
BF25_RS12245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF25_RS12255	COG0768	penicillin binding
BF25_RS12260	COG0604	alcohol dehydrogenase
BF25_RS12265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF25_RS12275	COG2205	protein histidine kinase activity
BF25_RS12285	COG1122	ATPase activity
BF25_RS12295	COG1794	racemase activity, acting on amino acids and derivatives
BF25_RS12300	COG1819	glycosyl
BF25_RS12305	COG0768	penicillin binding
BF25_RS12310	COG5002	protein histidine kinase activity
BF25_RS12320	COG0561	phosphatase activity
BF25_RS12355	COG2124	cytochrome p450
BF25_RS12430	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF25_RS12440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS12445	COG0460	homoserine dehydrogenase
BF25_RS12470	COG1136	(ABC) transporter
BF25_RS12500	COG0745	RESPONSE REGULATOR receiver
BF25_RS12510	COG3773	Cell wall hydrolase
BF25_RS12545	COG1063	alcohol dehydrogenase
BF25_RS12560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS12580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF25_RS12600	COG2814	Major facilitator Superfamily
BF25_RS12625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF25_RS12625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF25_RS12665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF25_RS12690	COG1686	Belongs to the peptidase S11 family
BF25_RS12695	COG2318	DinB family
BF25_RS12705	COG0572	uridine kinase
BF25_RS12710	COG1247	-acetyltransferase
BF25_RS12720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF25_RS12725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF25_RS12730	COG1024	Enoyl-CoA hydratase
BF25_RS12735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF25_RS12740	COG0511	ligase activity, forming carbon-carbon bonds
BF25_RS12745	COG0439	Biotin carboxylase
BF25_RS12750	COG1960	acyl-CoA dehydrogenase activity
BF25_RS12765	COG1309	transcriptional regulator
BF25_RS12775	COG1131	(ABC) transporter
BF25_RS12790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF25_RS12795	COG1252	NADH dehydrogenase
BF25_RS12805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS12820	COG0488	(ABC) transporter
BF25_RS12825	COG1309	transcriptional regulator
BF25_RS12845	COG1876	peptidase activity
BF25_RS12860	COG1476	TRANSCRIPTIONal
BF25_RS12865	COG0457	Tetratricopeptide repeat
BF25_RS12895	COG3718	enzyme involved in inositol metabolism
BF25_RS12900	COG0191	fructose-bisphosphate aldolase activity
BF25_RS12915	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS12925	COG0673	inositol 2-dehydrogenase activity
BF25_RS12930	COG2814	Major facilitator Superfamily
BF25_RS12935	COG1609	Transcriptional regulator
BF25_RS12940	COG0671	phosphoesterase, PA-phosphatase related
BF25_RS12945	COG2367	Beta-lactamase
BF25_RS12950	COG0768	penicillin binding
BF25_RS12955	COG0768	penicillin binding
BF25_RS12965	COG1595	DNA-templated transcription, initiation
BF25_RS12980	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF25_RS13020	COG1846	Transcriptional regulator
BF25_RS13025	COG3961	Belongs to the TPP enzyme family
BF25_RS13030	COG2226	methyltransferase
BF25_RS13040	COG3615	Tellurite resistance protein tehB
BF25_RS13040	COG0500	methyltransferase
BF25_RS13045	COG1136	(ABC) transporter
BF25_RS13060	COG1309	transcriptional regulator
BF25_RS13090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS13110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF25_RS13115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF25_RS13120	COG2971	BadF BadG BcrA BcrD
BF25_RS13170	COG1595	DNA-templated transcription, initiation
BF25_RS13175	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BF25_RS13200	COG1396	sequence-specific DNA binding
BF25_RS13220	COG1132	(ABC) transporter
BF25_RS13225	COG1132	(ABC) transporter
BF25_RS13240	COG2258	MOSC domain
BF25_RS13245	COG0583	DNA-binding transcription factor activity
BF25_RS13260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF25_RS13265	COG0583	DNA-binding transcription factor activity
BF25_RS13310	COG0561	phosphatase activity
BF25_RS13315	COG0010	Belongs to the arginase family
BF25_RS13330	COG1278	Cold shock
BF25_RS13340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS13350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF25_RS13380	COG1247	-acetyltransferase
BF25_RS13415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS13460	COG2226	methyltransferase
BF25_RS13480	COG2814	Major facilitator Superfamily
BF25_RS13485	COG0596	Alpha beta hydrolase
BF25_RS13495	COG1136	(ABC) transporter
BF25_RS13500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF25_RS13505	COG1187	pseudouridine synthase activity
BF25_RS13510	COG2329	Antibiotic biosynthesis monooxygenase
BF25_RS13530	COG1115	amino acid carrier protein
BF25_RS13540	COG2318	DinB family
BF25_RS13550	COG0776	regulation of translation
BF25_RS13565	COG2814	Major facilitator Superfamily
BF25_RS13570	COG3251	PFAM MbtH domain protein
BF25_RS13575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF25_RS13580	COG1535	isochorismatase
BF25_RS13580	COG3433	isochorismatase activity
BF25_RS13585	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF25_RS13590	COG1169	isochorismate synthase
BF25_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS13600	COG2223	nitrite transmembrane transporter activity
BF25_RS13630	COG0419	ATPase involved in DNA repair
BF25_RS13635	COG0420	3'-5' exonuclease activity
BF25_RS13650	COG1024	Enoyl-CoA hydratase
BF25_RS13655	COG1280	lysine exporter protein (LysE YggA)
BF25_RS13665	COG2084	Dehydrogenase
BF25_RS13670	COG1960	acyl-CoA dehydrogenase activity
BF25_RS13675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF25_RS13680	COG2079	MmgE PrpD family protein
BF25_RS13685	COG0372	Belongs to the citrate synthase family
BF25_RS13690	COG4841	protein insertion into membrane
BF25_RS13695	COG2814	Major facilitator Superfamily
BF25_RS13700	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF25_RS13700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF25_RS13740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF25_RS13830	COG1715	Restriction endonuclease
BF25_RS13830	COG1787	Restriction endonuclease
BF25_RS13860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF25_RS13865	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF25_RS13870	COG0671	phosphoesterase, PA-phosphatase related
BF25_RS13875	COG4326	sporulation control protein
BF25_RS13915	COG1509	lysine 2,3-aminomutase activity
BF25_RS13920	COG3829	transcription factor binding
BF25_RS13925	COG0456	acetyltransferase
BF25_RS13930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF25_RS13935	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF25_RS13940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF25_RS13945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF25_RS13960	COG5506	Protein of unknown function (DUF1694)
BF25_RS13965	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS13970	COG1253	flavin adenine dinucleotide binding
BF25_RS14005	COG1174	glycine betaine transport
BF25_RS14010	COG1125	glycine betaine transport
BF25_RS14010	COG0517	IMP dehydrogenase activity
BF25_RS14040	COG1070	Carbohydrate kinase
BF25_RS14045	COG1070	Carbohydrate kinase
BF25_RS14075	COG1064	alcohol dehydrogenase
BF25_RS14080	COG1737	Transcriptional regulator
BF25_RS14090	COG2197	response regulator
BF25_RS14095	COG2203	Gaf domain
BF25_RS14095	COG4585	Histidine kinase
BF25_RS14100	COG0668	transmembrane transport
BF25_RS14110	COG1051	belongs to the nudix hydrolase family
BF25_RS14135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF25_RS14140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS14160	COG0367	asparagine synthase
BF25_RS14165	COG0071	Belongs to the small heat shock protein (HSP20) family
BF25_RS14170	COG1999	signal sequence binding
BF25_RS14175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF25_RS14180	COG1307	EDD domain protein, DegV family
BF25_RS14190	COG0805	protein transport
BF25_RS14200	COG1272	protein, Hemolysin III
BF25_RS14205	COG0204	Acyl-transferase
BF25_RS14210	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF25_RS14215	COG0768	penicillin binding
BF25_RS14230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF25_RS14250	COG0546	phosphoglycolate phosphatase activity
BF25_RS14265	COG1131	(ABC) transporter
BF25_RS14280	COG0456	acetyltransferase
BF25_RS14290	COG1794	racemase activity, acting on amino acids and derivatives
BF25_RS14295	COG1454	alcohol dehydrogenase
BF25_RS14300	COG2610	gluconate transmembrane transporter activity
BF25_RS14325	COG0733	neurotransmitter:sodium symporter activity
BF25_RS14340	COG3850	Histidine kinase
BF25_RS14340	COG5002	protein histidine kinase activity
BF25_RS14345	COG0745	RESPONSE REGULATOR receiver
BF25_RS14350	COG0471	metal ion transport
BF25_RS14355	COG1929	Belongs to the glycerate kinase type-1 family
BF25_RS14450	COG1674	ftsk spoiiie
BF25_RS14470	COG0017	Asparaginyl-tRNA synthetase
BF25_RS14475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF25_RS14490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF25_RS14515	COG0018	arginyl-trna synthetase
BF25_RS14520	COG2136	Putative SAM-dependent methyltransferase
BF25_RS14520	COG2521	methyltransferase
BF25_RS14535	COG1413	lyase activity
BF25_RS14555	COG0629	single-stranded DNA binding
BF25_RS14570	COG0488	(ABC) transporter
BF25_RS14575	COG1418	mRNA catabolic process
BF25_RS14590	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF25_RS14605	COG2359	stage V sporulation protein S
BF25_RS14640	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF25_RS14645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF25_RS14650	COG2146	nitrite reductase [NAD(P)H] activity
BF25_RS14655	COG1587	Uroporphyrinogen-III synthase
BF25_RS14655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF25_RS14665	COG1648	precorrin-2 dehydrogenase activity
BF25_RS14680	COG2223	nitrite transmembrane transporter activity
BF25_RS14690	COG0314	molybdopterin synthase activity
BF25_RS14695	COG0303	'Molybdopterin
BF25_RS14700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF25_RS14705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF25_RS14710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF25_RS14730	COG2181	nitrate reductase activity
BF25_RS14735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF25_RS14740	COG1140	nitrate reductase beta subunit
BF25_RS14745	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF25_RS14760	COG0714	Associated with various cellular activities
BF25_RS14765	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF25_RS14770	COG1305	Transglutaminase-like
BF25_RS14775	COG0386	Belongs to the glutathione peroxidase family
BF25_RS14800	COG1595	DNA-templated transcription, initiation
BF25_RS14805	COG0604	alcohol dehydrogenase
BF25_RS14815	COG0346	lactoylglutathione lyase activity
BF25_RS14820	COG1082	Xylose isomerase domain protein TIM barrel
BF25_RS14840	COG2226	methyltransferase
BF25_RS14865	COG3874	Sporulation protein YtfJ
BF25_RS14915	COG0456	acetyltransferase
BF25_RS14940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS14945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS14950	COG1819	glycosyl
BF25_RS14965	COG4106	trans-aconitate 2-methyltransferase activity
BF25_RS14970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF25_RS14980	COG0561	phosphatase activity
BF25_RS15000	COG2211	Major facilitator Superfamily
BF25_RS15005	COG0154	amidase activity
BF25_RS15015	COG1876	peptidase activity
BF25_RS15025	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF25_RS15045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF25_RS15050	COG1114	Component of the transport system for branched-chain amino acids
BF25_RS15065	COG1253	flavin adenine dinucleotide binding
BF25_RS15070	COG2839	Protein conserved in bacteria
BF25_RS15075	COG0702	epimerase
BF25_RS15090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF25_RS15095	COG1607	acyl-coa hydrolase
BF25_RS15100	COG3689	TIGRFAM TIGR03943 family protein
BF25_RS15105	COG0701	Predicted permease
BF25_RS15115	COG2244	polysaccharide biosynthetic process
BF25_RS15120	COG0586	Pfam SNARE associated Golgi protein
BF25_RS15125	COG1051	belongs to the nudix hydrolase family
BF25_RS15130	COG5337	Spore coat protein CotH
BF25_RS15140	COG0406	alpha-ribazole phosphatase activity
BF25_RS15155	COG4166	transmembrane transport
BF25_RS15165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF25_RS15175	COG0702	epimerase
BF25_RS15185	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF25_RS15185	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF25_RS15250	COG0456	acetyltransferase
BF25_RS15255	COG0523	cobalamin synthesis protein
BF25_RS15260	COG4989	oxidoreductase activity
BF25_RS15270	COG1231	oxidoreductase activity
BF25_RS15280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF25_RS15295	COG0783	Belongs to the Dps family
BF25_RS15300	COG3949	Membrane
BF25_RS15320	COG0840	transmembrane signaling receptor activity
BF25_RS15345	COG2814	Major facilitator Superfamily
BF25_RS15350	COG0667	Aldo Keto reductase
BF25_RS15355	COG0640	Transcriptional regulator
BF25_RS15360	COG1404	Belongs to the peptidase S8 family
BF25_RS15365	COG2002	toxin-antitoxin pair type II binding
BF25_RS15405	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF25_RS15415	COG1279	arginine transmembrane transporter activity
BF25_RS15430	COG1082	Xylose isomerase domain protein TIM barrel
BF25_RS15440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF25_RS15460	COG1247	-acetyltransferase
BF25_RS15465	COG1285	pathogenesis
BF25_RS15480	COG5002	protein histidine kinase activity
BF25_RS15485	COG0745	RESPONSE REGULATOR receiver
BF25_RS15495	COG1316	TRANSCRIPTIONal
BF25_RS15520	COG0460	homoserine dehydrogenase
BF25_RS15555	COG0300	oxidoreductase activity
BF25_RS15565	COG5002	protein histidine kinase activity
BF25_RS15570	COG0745	RESPONSE REGULATOR receiver
BF25_RS15590	COG1388	LysM domain
BF25_RS15590	COG0791	NLP P60 protein
BF25_RS15605	COG1686	Belongs to the peptidase S11 family
BF25_RS15625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF25_RS15630	COG4988	ABC transporter
BF25_RS15635	COG1294	oxidase, subunit
BF25_RS15640	COG1271	oxidase subunit
BF25_RS15650	COG1846	Transcriptional regulator
BF25_RS15670	COG0583	DNA-binding transcription factor activity
BF25_RS15690	COG0411	ABC transporter
BF25_RS15700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF25_RS15705	COG2030	dehydratase
BF25_RS15710	COG0318	PFAM AMP-dependent synthetase and ligase
BF25_RS15725	COG0523	cobalamin synthesis protein
BF25_RS15730	COG1231	oxidoreductase activity
BF25_RS15740	COG0628	permease
BF25_RS15755	COG0778	Nitroreductase
BF25_RS15760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF25_RS15765	COG1959	2 iron, 2 sulfur cluster binding
BF25_RS15770	COG0583	DNA-binding transcription factor activity
BF25_RS15775	COG0697	spore germination
BF25_RS15785	COG4549	nuclear export factor GLE1
BF25_RS15790	COG2372	response to copper ion
BF25_RS15790	COG1276	copper resistance
BF25_RS15805	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF25_RS15820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF25_RS15835	COG2132	Multicopper oxidase
BF25_RS15840	COG0006	proline dipeptidase activity
BF25_RS15860	COG4224	UPF0291 protein
BF25_RS15865	COG4846	Membrane protein involved in cytochrome C biogenesis
BF25_RS15875	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF25_RS15880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS15890	COG2390	Transcriptional regulator
BF25_RS15925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF25_RS15940	COG1914	H( )-stimulated, divalent metal cation uptake system
BF25_RS15960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS15965	COG0535	radical SAM domain protein
BF25_RS15995	COG1073	alpha beta
BF25_RS16015	COG0427	acetyl-CoA hydrolase
BF25_RS16020	COG3279	Response regulator of the LytR AlgR family
BF25_RS16030	COG3384	dioxygenase
BF25_RS16035	COG2814	Major facilitator Superfamily
BF25_RS16060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF25_RS16070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF25_RS16075	COG0440	acetolactate synthase activity
BF25_RS16080	COG0028	Belongs to the TPP enzyme family
BF25_RS16085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF25_RS16095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF25_RS16110	COG2084	Dehydrogenase
BF25_RS16125	COG2323	membrane
BF25_RS16130	COG5566	PFAM Mor transcription activator
BF25_RS16140	COG0733	neurotransmitter:sodium symporter activity
BF25_RS16145	COG2244	polysaccharide biosynthetic process
BF25_RS16160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF25_RS16165	COG2223	nitrite transmembrane transporter activity
BF25_RS16180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF25_RS16190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF25_RS16205	COG1966	Carbon starvation protein
BF25_RS16220	COG2814	Major facilitator Superfamily
BF25_RS16230	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF25_RS16295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF25_RS16300	COG0784	Response regulator, receiver
BF25_RS16305	COG4191	Histidine kinase
BF25_RS16310	COG0281	malic enzyme
BF25_RS16315	COG1027	Aspartate ammonia-lyase
BF25_RS16325	COG0528	UMP kinase activity
BF25_RS16330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF25_RS16345	COG1131	(ABC) transporter
BF25_RS16380	COG2733	membrane
BF25_RS16415	COG0785	Cytochrome C biogenesis protein
BF25_RS16435	COG3340	Belongs to the peptidase S51 family
BF25_RS16465	COG0114	fumarate hydratase activity
BF25_RS16470	COG1757	Na H antiporter
BF25_RS16475	COG0438	transferase activity, transferring glycosyl groups
BF25_RS16475	COG1216	Glycosyl transferase, family 2
BF25_RS16485	COG0701	Predicted permease
BF25_RS16490	COG0523	cobalamin synthesis protein
BF25_RS16495	COG0697	spore germination
BF25_RS16500	COG1802	Transcriptional regulator
BF25_RS16530	COG0367	asparagine synthase
BF25_RS16560	COG0406	alpha-ribazole phosphatase activity
BF25_RS16570	COG1686	Belongs to the peptidase S11 family
BF25_RS16595	COG1234	tRNA 3'-trailer cleavage
BF25_RS16605	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF25_RS16615	COG0583	DNA-binding transcription factor activity
BF25_RS16640	COG2329	Antibiotic biosynthesis monooxygenase
BF25_RS16660	COG1309	transcriptional regulator
BF25_RS16685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF25_RS16690	COG4786	Flagellar basal body rod
BF25_RS16700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF25_RS16705	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF25_RS16715	COG1987	bacterial-type flagellum assembly
BF25_RS16720	COG1338	Plays a role in the flagellum-specific transport system
BF25_RS16730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF25_RS16730	COG1776	CheC inhibitor of MCP methylation
BF25_RS16745	COG0741	lytic transglycosylase activity
BF25_RS16750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF25_RS16805	COG0463	Glycosyl transferase, family 2
BF25_RS16855	COG1157	protein secretion by the type III secretion system
BF25_RS16865	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF25_RS16885	COG1558	bacterial-type flagellum-dependent cell motility
BF25_RS16890	COG1815	bacterial-type flagellum-dependent cell motility
BF25_RS16920	COG1256	bacterial-type flagellum assembly
BF25_RS16940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF25_RS16955	COG1776	CheC inhibitor of MCP methylation
BF25_RS16955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF25_RS16960	COG0643	Histidine kinase
BF25_RS16960	COG2198	Histidine kinase
BF25_RS16965	COG2201	protein-glutamate methylesterase activity
BF25_RS16970	COG1360	Flagellar Motor Protein
BF25_RS16975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF25_RS16985	COG1923	regulation of RNA biosynthetic process
BF25_RS17040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF25_RS17045	COG2323	membrane
BF25_RS17055	COG4978	Transcriptional regulator
BF25_RS17055	COG0789	Transcriptional regulator
BF25_RS17065	COG0475	glutathione-regulated potassium exporter activity
BF25_RS17075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF25_RS17080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF25_RS17085	COG3162	membrane
BF25_RS17100	COG1280	lysine exporter protein (LysE YggA)
BF25_RS17140	COG0328	RNA-DNA hybrid ribonuclease activity
BF25_RS17160	COG0454	-acetyltransferase
BF25_RS17175	COG0438	transferase activity, transferring glycosyl groups
BF25_RS17180	COG1215	transferase activity, transferring glycosyl groups
BF25_RS17195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF25_RS17220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF25_RS17235	COG0754	glutathionylspermidine amidase activity
BF25_RS17260	COG0456	acetyltransferase
BF25_RS17270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF25_RS17275	COG2311	Membrane
BF25_RS17280	COG2233	PERMEase
BF25_RS17290	COG0024	Methionine aminopeptidase
BF25_RS17295	COG3173	Aminoglycoside phosphotransferase
BF25_RS17305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF25_RS17310	COG1199	ATP-dependent helicase activity
BF25_RS17320	COG0116	Belongs to the methyltransferase superfamily
BF25_RS17370	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF25_RS17370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF25_RS17380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF25_RS17385	COG3935	DnaD domain protein
BF25_RS17405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF25_RS17405	COG1199	ATP-dependent helicase activity
BF25_RS17445	COG0438	transferase activity, transferring glycosyl groups
BF25_RS17450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF25_RS17465	COG1694	Mazg nucleotide pyrophosphohydrolase
BF25_RS17470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS17480	COG2738	Putative neutral zinc metallopeptidase
BF25_RS17495	COG4347	Protein of unknown function (DUF1405)
BF25_RS17505	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF25_RS17525	COG0457	Tetratricopeptide repeat
BF25_RS17530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF25_RS17550	COG0142	geranyltranstransferase activity
BF25_RS17560	COG0142	geranyltranstransferase activity
BF25_RS17575	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF25_RS17650	COG0492	ferredoxin-NADP+ reductase activity
BF25_RS17670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF25_RS17675	COG4862	establishment of competence for transformation
BF25_RS17695	COG1266	CAAX protease self-immunity
BF25_RS17700	COG0514	ATP-dependent DNA helicase (RecQ)
BF25_RS17705	COG4955	Helix-turn-helix domain
BF25_RS17710	COG1141	Ferredoxin
BF25_RS17715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF25_RS17730	COG2096	Adenosyltransferase
BF25_RS17735	COG5002	protein histidine kinase activity
BF25_RS17740	COG0745	RESPONSE REGULATOR receiver
BF25_RS17745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF25_RS17750	COG1333	cytochrome c biogenesis protein
BF25_RS17760	COG1187	pseudouridine synthase activity
BF25_RS17765	COG0700	Nucleoside recognition
BF25_RS17770	COG2715	membrane protein required for spore maturation
BF25_RS17775	COG1686	Belongs to the peptidase S11 family
BF25_RS17780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF25_RS17795	COG0392	lysyltransferase activity
BF25_RS17795	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF25_RS17815	COG5002	protein histidine kinase activity
BF25_RS17820	COG0582	viral genome integration into host DNA
BF25_RS17830	COG1801	Protein of unknown function DUF72
BF25_RS17850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF25_RS17855	COG1392	Phosphate transport regulator
BF25_RS17860	COG0306	phosphate transporter
BF25_RS17865	COG0730	response to heat
BF25_RS17885	COG1017	nitric oxide dioxygenase activity
BF25_RS17885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF25_RS17910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF25_RS17920	COG1114	Component of the transport system for branched-chain amino acids
BF25_RS17930	COG2197	response regulator
BF25_RS17935	COG4585	Histidine kinase
BF25_RS17940	COG4758	membrane
BF25_RS17955	COG1757	Na H antiporter
BF25_RS17975	COG0733	neurotransmitter:sodium symporter activity
BF25_RS17985	COG1648	precorrin-2 dehydrogenase activity
BF25_RS18005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF25_RS18010	COG0529	Catalyzes the synthesis of activated sulfate
BF25_RS18030	COG0019	diaminopimelate decarboxylase activity
BF25_RS18040	COG1368	sulfuric ester hydrolase activity
BF25_RS18045	COG1183	phosphatidylcholine synthase activity
BF25_RS18060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF25_RS18095	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF25_RS18120	COG0473	3-isopropylmalate dehydrogenase activity
BF25_RS18130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF25_RS18135	COG0440	acetolactate synthase activity
BF25_RS18140	COG0028	Belongs to the TPP enzyme family
BF25_RS18145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF25_RS18175	COG3874	Sporulation protein YtfJ
BF25_RS18180	COG4709	membrane
BF25_RS18185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF25_RS18190	COG1301	dicarboxylic acid transport
BF25_RS18200	COG1846	Transcriptional regulator
BF25_RS18215	COG1968	undecaprenyl-diphosphatase activity
BF25_RS18220	COG0534	Mate efflux family protein
BF25_RS18240	COG3173	Aminoglycoside phosphotransferase
BF25_RS18255	COG0716	FMN binding
BF25_RS18280	COG1696	Membrane protein involved in D-alanine export
BF25_RS18290	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF25_RS18295	COG2070	2-Nitropropane dioxygenase
BF25_RS18300	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF25_RS18310	COG1335	isochorismatase
BF25_RS18320	COG1522	sequence-specific DNA binding
BF25_RS18335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF25_RS18340	COG1131	(ABC) transporter
BF25_RS18350	COG1131	(ABC) transporter
BF25_RS18355	COG1725	Transcriptional regulator
BF25_RS18360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF25_RS18365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF25_RS18375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF25_RS18380	COG1780	Probably involved in ribonucleotide reductase function
BF25_RS18415	COG4873	Protein conserved in bacteria
BF25_RS18430	COG0720	synthase
BF25_RS18440	COG5002	protein histidine kinase activity
BF25_RS18450	COG2318	DinB family
BF25_RS18460	COG1846	Transcriptional regulator
BF25_RS18465	COG3852	Histidine kinase
BF25_RS18475	COG2861	carbohydrate metabolic process
BF25_RS18485	COG0235	Class ii aldolase
BF25_RS18500	COG1349	DNA-binding transcription factor activity
BF25_RS18530	COG1840	ABC-type Fe3 transport system, periplasmic component
BF25_RS18545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF25_RS18550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF25_RS18555	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF25_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS18580	COG2030	dehydratase
BF25_RS18590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF25_RS18595	COG0861	Integral membrane protein TerC family
BF25_RS18600	COG2116	formate transmembrane transporter activity
BF25_RS18610	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF25_RS18630	COG2186	Transcriptional regulator
BF25_RS18635	COG5002	protein histidine kinase activity
BF25_RS18640	COG0745	RESPONSE REGULATOR receiver
BF25_RS18650	COG3835	regulator
BF25_RS18655	COG0277	FAD linked oxidase domain protein
BF25_RS18660	COG0247	lactate metabolic process
BF25_RS18665	COG2340	Cysteine-rich secretory protein family
BF25_RS18675	COG0564	pseudouridine synthase activity
BF25_RS18685	COG2409	Drug exporters of the RND superfamily
BF25_RS18695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF25_RS18700	COG1177	transmembrane transport
BF25_RS18705	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF25_RS18710	COG3842	ATPase activity
BF25_RS18715	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS18750	COG0681	Belongs to the peptidase S26 family
BF25_RS18755	COG1686	Belongs to the peptidase S11 family
BF25_RS18765	COG2226	methyltransferase
BF25_RS18825	COG1476	TRANSCRIPTIONal
BF25_RS18835	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF25_RS18885	COG5634	Uncharacterized conserved protein (DUF2278)
BF25_RS18890	COG1620	l-lactate permease
BF25_RS18925	COG0512	Glutamine amidotransferase of anthranilate synthase
BF25_RS18925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF25_RS18940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF25_RS18945	COG5492	domain, Protein
BF25_RS18960	COG2382	esterase
BF25_RS18970	COG2153	protein acetylation
BF25_RS19015	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF25_RS19030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF25_RS19050	COG0463	Glycosyl transferase, family 2
BF25_RS19050	COG0457	Tetratricopeptide repeat
BF25_RS19070	COG1216	Glycosyl transferase, family 2
BF25_RS19070	COG0463	Glycosyl transferase, family 2
BF25_RS19090	COG0564	pseudouridine synthase activity
BF25_RS19100	COG2357	RelA SpoT domain protein
BF25_RS19110	COG4116	CYTH
BF25_RS19115	COG2346	COG2346, Truncated hemoglobins
BF25_RS19120	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF25_RS19130	COG1164	Oligoendopeptidase f
BF25_RS19140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF25_RS19145	COG4862	establishment of competence for transformation
BF25_RS19150	COG0861	Integral membrane protein TerC family
BF25_RS19170	COG4166	transmembrane transport
BF25_RS19175	COG0534	Mate efflux family protein
BF25_RS19180	COG4608	Belongs to the ABC transporter superfamily
BF25_RS19185	COG0444	Belongs to the ABC transporter superfamily
BF25_RS19190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF25_RS19195	COG0601	transmembrane transport
BF25_RS19200	COG4166	transmembrane transport
BF25_RS19210	COG0180	Tryptophanyl-tRNA synthetase
BF25_RS19220	COG5504	Zn-dependent protease
BF25_RS19225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF25_RS19230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF25_RS19245	COG2267	carboxylic ester hydrolase activity
BF25_RS19255	COG0542	response to heat
BF25_RS19270	COG0561	phosphatase activity
BF25_RS19285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS19295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF25_RS19305	COG2996	Protein conserved in bacteria
BF25_RS19335	COG0753	catalase activity
BF25_RS19340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF25_RS19345	COG0367	asparagine synthase
BF25_RS19370	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF25_RS19415	COG1074	ATP-dependent DNA helicase activity
BF25_RS19420	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF25_RS19430	COG0398	Pfam SNARE associated Golgi protein
BF25_RS19435	COG4903	ComK protein
BF25_RS19460	COG2224	Isocitrate lyase
BF25_RS19465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF25_RS19485	COG0697	spore germination
BF25_RS19490	COG0840	transmembrane signaling receptor activity
BF25_RS19495	COG0501	Belongs to the peptidase M48B family
BF25_RS19520	COG0745	RESPONSE REGULATOR receiver
BF25_RS19525	COG2205	protein histidine kinase activity
BF25_RS19540	COG2207	Transcriptional regulator
BF25_RS19540	COG3708	Transcriptional regulator
BF25_RS19545	COG1595	DNA-templated transcription, initiation
BF25_RS19555	COG1078	dGTPase activity
BF25_RS19560	COG1408	metallophosphoesterase
BF25_RS19605	COG3209	COG3209 Rhs family protein
BF25_RS19635	COG0318	PFAM AMP-dependent synthetase and ligase
BF25_RS19645	COG0095	Lipoate-protein ligase
BF25_RS19650	COG1234	tRNA 3'-trailer cleavage
BF25_RS19660	COG1609	Transcriptional regulator
BF25_RS19685	COG1511	domain protein
BF25_RS19690	COG1309	transcriptional regulator
BF25_RS19725	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF25_RS19730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF25_RS19735	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF25_RS19740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF25_RS19745	COG2329	Antibiotic biosynthesis monooxygenase
BF25_RS19750	COG3428	Bacterial PH domain
BF25_RS19755	COG3402	PFAM membrane-flanked domain
BF25_RS19810	COG3402	PFAM membrane-flanked domain
BF25_RS19820	COG1309	transcriptional regulator
BF25_RS19830	COG4473	ABC transporter
BF25_RS19835	COG1131	(ABC) transporter
BF25_RS19840	COG0537	adenosine 5'-monophosphoramidase activity
BF25_RS19845	COG4980	gas vesicle protein
BF25_RS19870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF25_RS19875	COG3973	AAA domain
BF25_RS19885	COG0477	Major facilitator Superfamily
BF25_RS19890	COG0477	Major facilitator Superfamily
BF25_RS19930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF25_RS19940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF25_RS19945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF25_RS19965	COG2267	carboxylic ester hydrolase activity
BF25_RS19970	COG0457	Tetratricopeptide repeat
BF25_RS19975	COG0346	lactoylglutathione lyase activity
BF25_RS19980	COG0346	lactoylglutathione lyase activity
BF25_RS19985	COG2814	Major facilitator Superfamily
BF25_RS19990	COG1309	transcriptional regulator
BF25_RS20010	COG4717	serine-type aminopeptidase activity
BF25_RS20015	COG0420	3'-5' exonuclease activity
BF25_RS20075	COG2205	protein histidine kinase activity
BF25_RS20075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF25_RS20075	COG0784	Response regulator, receiver
BF25_RS20075	COG2198	Histidine kinase
BF25_RS20080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF25_RS20085	COG2208	phosphoserine phosphatase activity
BF25_RS20095	COG1191	sigma factor activity
BF25_RS20120	COG3237	CsbD-like
BF25_RS20170	COG2770	Histidine kinase
BF25_RS20170	COG3437	response regulator, receiver
BF25_RS20195	COG1959	2 iron, 2 sulfur cluster binding
BF25_RS20200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF25_RS20215	COG2376	Dihydroxyacetone kinase
BF25_RS20235	COG1183	phosphatidylcholine synthase activity
BF25_RS20255	COG1309	transcriptional regulator
BF25_RS20260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF25_RS20260	COG3320	Male sterility
BF25_RS20310	COG0477	Major facilitator Superfamily
BF25_RS20350	COG0305	Participates in initiation and elongation during chromosome replication
BF25_RS20365	COG0789	Transcriptional regulator
BF25_RS20365	COG4978	Transcriptional regulator
BF25_RS20395	COG3181	Tripartite tricarboxylate transporter family receptor
BF25_RS20400	COG4565	transcriptional regulatory protein
BF25_RS20405	COG3290	protein histidine kinase activity
BF25_RS20410	COG0477	Major facilitator Superfamily
BF25_RS20440	COG4608	Belongs to the ABC transporter superfamily
BF25_RS20450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF25_RS20455	COG0601	transmembrane transport
BF25_RS20495	COG3938	Belongs to the proline racemase family
BF25_RS20515	COG1363	Peptidase, m42
BF25_RS20535	COG1024	Enoyl-CoA hydratase
BF25_RS20550	COG1696	Membrane protein involved in D-alanine export
BF25_RS20565	COG4196	transglutaminase domain protein
BF25_RS20570	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF25_RS20580	COG2244	polysaccharide biosynthetic process
BF25_RS20585	COG0653	protein targeting
BF25_RS20605	COG0659	secondary active sulfate transmembrane transporter activity
BF25_RS20620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF25_RS20635	COG0561	phosphatase activity
BF25_RS20650	COG3527	Alpha-acetolactate decarboxylase
BF25_RS20655	COG0028	Belongs to the TPP enzyme family
BF25_RS20685	COG0189	ligase activity
BF25_RS20700	COG1126	abc transporter atp-binding protein
BF25_RS20705	COG0765	amino acid transport
BF25_RS20710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF25_RS20720	COG1132	(ABC) transporter
BF25_RS20730	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS20740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF25_RS20745	COG0531	amino acid
BF25_RS20755	COG0753	catalase activity
BF25_RS20755	COG0693	protein deglycase activity
BF25_RS20760	COG0693	protein deglycase activity
BF25_RS20770	COG2211	Major facilitator Superfamily
BF25_RS20775	COG4533	DNA binding
BF25_RS20780	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF25_RS20790	COG1733	regulation of RNA biosynthetic process
BF25_RS20795	COG2814	Major facilitator Superfamily
BF25_RS20800	COG1309	transcriptional regulator
BF25_RS20805	COG2076	Multidrug Resistance protein
BF25_RS20820	COG1522	sequence-specific DNA binding
BF25_RS20825	COG0697	spore germination
BF25_RS20840	COG2259	Doxx family
BF25_RS20850	COG1263	PTS System
BF25_RS20850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF25_RS20860	COG1737	Transcriptional regulator
BF25_RS20870	COG0475	glutathione-regulated potassium exporter activity
BF25_RS20875	COG0531	amino acid
BF25_RS20910	COG0586	Pfam SNARE associated Golgi protein
BF25_RS20945	COG3546	catalase activity
BF25_RS20950	COG1114	Component of the transport system for branched-chain amino acids
BF25_RS20965	COG5522	Integral membrane protein (intg_mem_TP0381)
BF25_RS20975	COG1136	(ABC) transporter
BF25_RS20980	COG0577	efflux transmembrane transporter activity
BF25_RS20985	COG1388	LysM domain
BF25_RS20985	COG3584	3D domain protein
BF25_RS21005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF25_RS21010	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF25_RS21015	COG3711	transcriptional antiterminator
BF25_RS21015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF25_RS21030	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF25_RS21035	COG0604	alcohol dehydrogenase
BF25_RS21040	COG1316	TRANSCRIPTIONal
BF25_RS21050	COG0730	response to heat
BF25_RS21055	COG2210	Belongs to the sulfur carrier protein TusA family
BF25_RS21070	COG0425	Belongs to the sulfur carrier protein TusA family
BF25_RS21075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS21075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF25_RS21080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF25_RS21080	COG0425	Belongs to the sulfur carrier protein TusA family
BF25_RS21085	COG1937	Protein conserved in bacteria
BF25_RS21090	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF25_RS21115	COG2719	SpoVR family
BF25_RS21120	COG0778	Nitroreductase
BF25_RS21160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF25_RS21165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF25_RS21175	COG1609	Transcriptional regulator
BF25_RS21180	COG1263	PTS System
BF25_RS21180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF25_RS21185	COG1621	beta-fructofuranosidase activity
BF25_RS21190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF25_RS21205	COG1028	Short-chain dehydrogenase reductase Sdr
BF25_RS21210	COG2252	PERMEase
BF25_RS21225	COG1846	Transcriptional regulator
BF25_RS21230	COG2814	Major facilitator Superfamily
BF25_RS21235	COG2205	protein histidine kinase activity
BF25_RS21280	COG0351	phosphomethylpyrimidine kinase
BF25_RS21285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF25_RS21295	COG2104	thiamine diphosphate biosynthetic process
BF25_RS21300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF25_RS21305	COG0352	thiamine-phosphate diphosphorylase activity
BF25_RS21310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF25_RS21315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF25_RS21320	COG1116	anion transmembrane transporter activity
BF25_RS21325	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF25_RS21350	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF25_RS21470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF25_RS21480	COG0581	inorganic phosphate transmembrane transporter activity
BF25_RS21485	COG0573	inorganic phosphate transmembrane transporter activity
BF25_RS21490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF25_RS21495	COG1918	ferrous iron import across plasma membrane
BF25_RS21495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF25_RS21500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF25_RS21505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF25_RS21520	COG0531	amino acid
BF25_RS21525	COG0697	spore germination
BF25_RS21530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF25_RS21545	COG4990	cell redox homeostasis
BF25_RS21550	COG0833	amino acid
BF25_RS21555	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF25_RS21560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF25_RS21575	COG0475	glutathione-regulated potassium exporter activity
BF25_RS21575	COG0569	domain protein
BF25_RS21600	COG2252	PERMEase
BF25_RS21605	COG1113	amino acid transport
BF25_RS21620	COG1114	Component of the transport system for branched-chain amino acids
BF25_RS21625	COG3104	oligopeptide transport
BF25_RS21640	COG1476	TRANSCRIPTIONal
BF25_RS21645	COG3584	3D domain protein
BF25_RS21645	COG1388	LysM domain
BF25_RS21650	COG0840	transmembrane signaling receptor activity
BF25_RS21655	COG1968	undecaprenyl-diphosphatase activity
BF25_RS21680	COG3568	Endonuclease Exonuclease Phosphatase
BF25_RS21695	COG1063	alcohol dehydrogenase
BF25_RS21720	COG1879	ABC-type sugar transport system periplasmic component
BF25_RS21725	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF25_RS21740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF25_RS21745	COG1609	Transcriptional regulator
BF25_RS21760	COG1846	Transcriptional regulator
BF25_RS21765	COG2271	Major facilitator Superfamily
BF25_RS21775	COG4608	Belongs to the ABC transporter superfamily
BF25_RS21780	COG0601	transmembrane transport
BF25_RS21790	COG0747	negative chemotaxis
BF25_RS21805	COG0659	secondary active sulfate transmembrane transporter activity
BF25_RS21820	COG5002	protein histidine kinase activity
BF25_RS21825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF25_RS21830	COG2378	regulation of single-species biofilm formation
BF25_RS21855	COG0833	amino acid
BF25_RS21860	COG0765	amino acid transport
BF25_RS21865	COG0765	amino acid transport
BF25_RS21870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF25_RS21875	COG1126	abc transporter atp-binding protein
BF25_RS21880	COG1115	amino acid carrier protein
BF25_RS21885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF25_RS21895	COG0697	spore germination
BF25_RS21910	COG0366	Alpha amylase catalytic
BF25_RS21915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF25_RS21915	COG1263	PTS System
BF25_RS21920	COG2188	Transcriptional regulator
BF25_RS21925	COG0531	amino acid
BF25_RS21945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF25_RS21950	COG0714	Associated with various cellular activities
BF25_RS21955	COG4548	von Willebrand factor, type A
BF25_RS21970	COG0156	8-amino-7-oxononanoate synthase activity
BF25_RS21975	COG2226	methyltransferase
BF25_RS21985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS21990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS21995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS22000	COG3104	oligopeptide transport
BF25_RS22015	COG1620	l-lactate permease
BF25_RS22020	COG1027	Aspartate ammonia-lyase
BF25_RS22025	COG1253	flavin adenine dinucleotide binding
BF25_RS22030	COG0346	lactoylglutathione lyase activity
BF25_RS22035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS22040	COG1316	TRANSCRIPTIONal
BF25_RS22045	COG2720	vancomycin resistance protein
BF25_RS22065	COG3227	Zinc metalloprotease (Elastase)
BF25_RS22075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF25_RS22080	COG2217	Heavy metal translocating P-type atpase
BF25_RS22085	COG0640	Transcriptional regulator
BF25_RS22090	COG0531	amino acid
BF25_RS22105	COG2427	Protein of unknown function (DUF1641)
BF25_RS22110	COG3383	formate dehydrogenase (NAD+) activity
BF25_RS22115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF25_RS22120	COG0456	acetyltransferase
BF25_RS22120	COG0454	-acetyltransferase
BF25_RS22130	COG0745	RESPONSE REGULATOR receiver
BF25_RS22135	COG5002	protein histidine kinase activity
BF25_RS22145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF25_RS22160	COG0281	malic enzyme
BF25_RS22165	COG3493	citrate carrier protein
BF25_RS22170	COG4565	transcriptional regulatory protein
BF25_RS22175	COG3290	protein histidine kinase activity
BF25_RS22185	COG4990	cell redox homeostasis
BF25_RS22195	COG5002	protein histidine kinase activity
BF25_RS22200	COG0745	RESPONSE REGULATOR receiver
BF25_RS22205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF25_RS22215	COG0395	ABC-type sugar transport system, permease component
BF25_RS22220	COG1175	transmembrane transport
BF25_RS22225	COG3842	ATPase activity
BF25_RS22230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF25_RS22250	COG2851	Citrate transporter
BF25_RS22260	COG3290	protein histidine kinase activity
BF25_RS22270	COG2268	Band 7 protein
BF25_RS22275	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF25_RS22285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF25_RS22310	COG2766	serine protein kinase
BF25_RS22325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF25_RS22335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF25_RS22345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF25_RS22350	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF25_RS22465	COG0735	belongs to the Fur family
BF25_RS22470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF25_RS22490	COG4555	ABC transporter
BF25_RS22500	COG0070	glutamate synthase
BF25_RS22500	COG0067	glutamate synthase
BF25_RS22500	COG0069	glutamate synthase activity
BF25_RS22505	COG4129	membrane
BF25_RS22510	COG1132	(ABC) transporter
BF25_RS22535	COG1194	a g-specific adenine glycosylase
BF25_RS22540	COG1988	membrane-bound metal-dependent
BF25_RS22570	COG1090	epimerase
BF25_RS22575	COG1228	amidohydrolase
BF25_RS22595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF25_RS22615	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF25_RS22615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF25_RS22630	COG0463	Glycosyl transferase, family 2
BF25_RS22645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF25_RS22650	COG1263	PTS System
BF25_RS22650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF25_RS22685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF25_RS22690	COG0833	amino acid
BF25_RS22700	COG3829	transcription factor binding
BF25_RS22710	COG0101	tRNA pseudouridine synthase activity
BF25_RS22935	COG1484	DNA-dependent DNA replication
BF25_RS22970	COG1396	sequence-specific DNA binding
BF25_RS22985	COG1396	sequence-specific DNA binding
BF25_RS22990	COG0582	viral genome integration into host DNA
BF25_RS22995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF25_RS23000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF25_RS23025	COG0535	radical SAM domain protein
BF25_RS23035	COG0387	Pfam Sodium calcium exchanger
BF25_RS23040	COG3871	stress protein (general stress protein 26)
BF25_RS23055	COG0586	Pfam SNARE associated Golgi protein
BF25_RS23075	COG0697	spore germination
BF25_RS23080	COG2217	Heavy metal translocating P-type atpase
BF25_RS23085	COG1295	ribonuclease BN
BF25_RS23095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF25_RS23110	COG3853	Toxic anion resistance protein (TelA)
BF25_RS23120	COG0861	Integral membrane protein TerC family
BF25_RS23125	COG2310	stress, protein
BF25_RS23130	COG2310	stress, protein
BF25_RS23135	COG2310	stress, protein
BF25_RS23150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF25_RS23165	COG2270	Major facilitator Superfamily
BF25_RS23210	COG0488	(ABC) transporter
BF25_RS23215	COG1116	anion transmembrane transporter activity
BF25_RS23225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF25_RS23240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF25_RS23270	COG2190	(PTS) system
BF25_RS23270	COG1263	PTS System
BF25_RS23270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF25_RS23275	COG0366	Alpha amylase catalytic
BF25_RS23280	COG0840	transmembrane signaling receptor activity
BF25_RS23285	COG0840	transmembrane signaling receptor activity
BF25_RS23295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF25_RS23300	COG0765	amino acid transport
BF25_RS23310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF25_RS23310	COG0723	plastoquinol--plastocyanin reductase activity
BF25_RS23315	COG2814	Major facilitator Superfamily
BF25_RS23320	COG3541	Predicted nucleotidyltransferase
BF25_RS23340	COG5002	protein histidine kinase activity
BF25_RS23375	COG0166	Belongs to the GPI family
BF25_RS23395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS23400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS23405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS23425	COG0450	alkyl hydroperoxide reductase
BF25_RS23440	COG1473	amidohydrolase
BF25_RS23445	COG1757	Na H antiporter
BF25_RS23470	COG4807	Protein conserved in bacteria
BF25_RS23480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF25_RS23485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF25_RS23490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS23505	COG2309	aminopeptidase activity
BF25_RS23510	COG2076	Multidrug Resistance protein
BF25_RS23515	COG1012	belongs to the aldehyde dehydrogenase family
BF25_RS23525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF25_RS23530	COG0546	phosphoglycolate phosphatase activity
BF25_RS23535	COG1597	lipid kinase activity
BF25_RS23560	COG1846	Transcriptional regulator
BF25_RS23580	COG1464	Belongs to the NlpA lipoprotein family
BF25_RS23585	COG2011	ABC-type metal ion transport system permease component
BF25_RS23590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF25_RS23595	COG1335	isochorismatase
BF25_RS23615	COG4851	CamS sex pheromone cAM373 precursor
BF25_RS23625	COG0210	DNA helicase
BF25_RS23650	COG0151	Belongs to the GarS family
BF25_RS23660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF25_RS23670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF25_RS23685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF25_RS23695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF25_RS23700	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF25_RS23705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF25_RS23730	COG0745	RESPONSE REGULATOR receiver
BF25_RS23735	COG2205	protein histidine kinase activity
BF25_RS23750	COG1968	undecaprenyl-diphosphatase activity
BF25_RS23770	COG1215	transferase activity, transferring glycosyl groups
BF25_RS23780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF25_RS23790	COG2226	methyltransferase
BF25_RS23830	COG5002	protein histidine kinase activity
BF25_RS23840	COG2252	PERMEase
BF25_RS23860	COG1266	CAAX protease self-immunity
BF25_RS23875	COG0488	(ABC) transporter
BF25_RS23885	COG0456	acetyltransferase
BF25_RS23890	COG1214	PFAM Peptidase M22, glycoprotease
BF25_RS23895	COG0802	atpase or kinase
BF25_RS23990	COG2183	response to ionizing radiation
BF25_RS23995	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF25_RS24000	COG0864	Transcriptional regulator
BF25_RS24005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF25_RS24010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF25_RS24020	COG0457	Tetratricopeptide repeat
BF25_RS24020	COG0705	Rhomboid family
BF25_RS24025	COG4294	response to UV
BF25_RS24035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF25_RS24050	COG2814	Major facilitator Superfamily
BF25_RS24060	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF25_RS24065	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF25_RS24090	COG4608	Belongs to the ABC transporter superfamily
BF25_RS24095	COG0444	Belongs to the ABC transporter superfamily
BF25_RS24100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF25_RS24105	COG0601	transmembrane transport
BF25_RS24110	COG0747	negative chemotaxis
BF25_RS24125	COG0488	(ABC) transporter
BF25_RS24150	COG5298	Protein conserved in bacteria
BF25_RS24155	COG0084	hydrolase, TatD family'
BF25_RS24170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS24180	COG1609	Transcriptional regulator
BF25_RS24190	COG0204	Acyl-transferase
BF25_RS24200	COG0697	spore germination
BF25_RS24205	COG0583	DNA-binding transcription factor activity
BF25_RS24220	COG1910	domain protein
BF25_RS24235	COG4149	molybdate abc transporter
BF25_RS24240	COG4975	Glucose uptake
BF25_RS24255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF25_RS24260	COG0656	L-ascorbic acid biosynthetic process
BF25_RS24265	COG4166	transmembrane transport
BF25_RS24270	COG4166	transmembrane transport
BF25_RS24285	COG2207	Transcriptional regulator
BF25_RS24295	COG4166	transmembrane transport
BF25_RS24300	COG4608	Belongs to the ABC transporter superfamily
BF25_RS24305	COG0444	Belongs to the ABC transporter superfamily
BF25_RS24310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF25_RS24315	COG0601	transmembrane transport
BF25_RS24330	COG2814	Major facilitator Superfamily
BF25_RS24340	COG2271	Major facilitator Superfamily
BF25_RS24345	COG0277	FAD linked oxidase domain protein
BF25_RS24355	COG0604	alcohol dehydrogenase
BF25_RS24360	COG1464	Belongs to the NlpA lipoprotein family
BF25_RS24365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF25_RS24370	COG2011	ABC-type metal ion transport system permease component
BF25_RS24410	COG0823	Involved in the tonB-independent uptake of proteins
BF25_RS24410	COG1506	peptidase
BF25_RS24410	COG4946	Tricorn protease homolog
BF25_RS24415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF25_RS24435	COG0596	Alpha beta hydrolase
BF25_RS24440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF25_RS24455	COG4856	YbbR-like protein
BF25_RS24460	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF25_RS24545	COG0726	polysaccharide deacetylase
BF25_RS24550	COG2194	sulfuric ester hydrolase activity
BF25_RS24560	COG0489	protein tyrosine kinase activity
BF25_RS24565	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF25_RS24590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF25_RS24625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF25_RS24635	COG0024	Methionine aminopeptidase
BF25_RS24645	COG0201	protein transport
BF25_RS24705	COG0255	Belongs to the universal ribosomal protein uL29 family
BF25_RS24775	COG1358	cellular component organization or biogenesis
BF25_RS24780	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF25_RS24790	COG2813	Specifically methylates the guanine in position
BF25_RS24810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BF25_RS24815	COG0250	Participates in transcription elongation, termination and antitermination
BF25_RS24820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF25_RS24835	COG3688	RNA-binding protein containing a PIN domain
BF25_RS24840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF25_RS24855	COG1045	serine acetyltransferase
BF25_RS24875	COG4956	integral membrane protein (PIN domain superfamily)
BF25_RS24885	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF25_RS24890	COG0542	response to heat
BF25_RS24900	COG3880	PFAM UvrB UvrC protein
BF25_RS24930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF25_RS24935	COG1396	sequence-specific DNA binding
BF25_RS24940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF25_RS24945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF25_RS24950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF25_RS24955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF25_RS24960	COG0512	Glutamine amidotransferase of anthranilate synthase
BF25_RS24965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF25_RS24970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF25_RS24985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF25_RS24990	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF25_RS24995	COG0037	tRNA processing
BF25_RS25000	COG2208	phosphoserine phosphatase activity
BF25_RS25015	COG1098	S1 RNA binding domain
BF25_RS25035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF25_RS25040	COG3956	TIGRFAM MazG family protein
BF25_RS25045	COG2244	polysaccharide biosynthetic process
BF25_RS25050	COG2002	toxin-antitoxin pair type II binding
BF25_RS25055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF25_RS25085	COG0251	oxidation-reduction process
BF25_RS25090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF25_RS25105	COG4466	Protein conserved in bacteria
BF25_RS25120	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF25_RS25125	COG0084	hydrolase, TatD family'
BF25_RS25130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF25_RS25130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF25_RS25135	COG2002	toxin-antitoxin pair type II binding
BF25_RS25140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF25_RS25150	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF25_RS25160	COG1774	PSP1 C-terminal conserved region
BF25_RS25165	COG0470	DNA polymerase III
BF25_RS25175	COG1982	Orn Lys Arg decarboxylase major
BF25_RS25230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF25_RS25235	COG0590	tRNA wobble adenosine to inosine editing
BF25_RS25245	COG1335	isochorismatase
BF25_RS25250	COG1428	Deoxynucleoside kinase
BF25_RS25255	COG1428	Deoxynucleoside kinase
BF25_RS25285	COG1686	Belongs to the peptidase S11 family
BF25_RS25290	COG0516	GMP reductase activity
BF25_RS25290	COG0517	IMP dehydrogenase activity
BF25_RS25325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF25_RS25330	COG0187	DNA topoisomerase II activity
BF25_RS25340	COG2501	S4 domain
BF25_RS25345	COG0592	DNA-directed DNA polymerase activity
BF25_RS25355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BF25_RS25365	COG0706	membrane insertase activity
BF25_RS25370	COG1847	R3H domain protein
BF25_RS25395	COG1192	Involved in chromosome partitioning
BF25_RS25400	COG1475	DNA binding
BF25_RS25410	COG0668	transmembrane transport
BF25_RS25415	COG4481	Protein conserved in bacteria
BF25_RS25420	COG0012	GTP binding
BF25_RS25430	COG0629	single-stranded DNA binding
BF25_RS25440	COG4241	membrane
BF25_RS25445	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF25_RS25455	COG0305	Participates in initiation and elongation during chromosome replication
BF25_RS25485	COG0745	RESPONSE REGULATOR receiver
BF25_RS25490	COG5002	protein histidine kinase activity
BF25_RS25495	COG4863	YycH protein
BF25_RS25500	COG4853	Protein conserved in bacteria
BF25_RS25505	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF25_RS25510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF25_RS25530	COG1164	Oligoendopeptidase f
BF25_RS25535	COG0516	GMP reductase activity
BF25_RS25555	COG1272	protein, Hemolysin III
BF25_RS25560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF25_RS25580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF25_RS25585	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF25_RS25590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF25_RS25595	COG2814	Major facilitator Superfamily
BF25_RS25600	COG3275	phosphorelay sensor kinase activity
BF25_RS25605	COG3279	Response regulator of the LytR AlgR family
BF25_RS25620	COG0628	permease
BF25_RS25625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF25_RS25625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF25_RS25630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF25_RS25635	COG1309	transcriptional regulator
BF25_RS25640	COG0463	Glycosyl transferase, family 2
BF25_RS25665	COG0488	(ABC) transporter
BF25_RS25680	COG1607	acyl-coa hydrolase
BF25_RS25690	COG0840	transmembrane signaling receptor activity
BF25_RS25715	COG0477	Major facilitator Superfamily
BF25_RS25720	COG3279	Response regulator of the LytR AlgR family
BF25_RS25725	COG1966	Carbon starvation protein
BF25_RS25730	COG2879	small protein
BF25_RS25735	COG3706	GGDEF domain
BF25_RS25740	COG0351	phosphomethylpyrimidine kinase
BF25_RS25750	COG2197	response regulator
BF25_RS25760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF25_RS25765	COG1011	Hydrolase
BF25_RS25775	COG2873	o-acetylhomoserine
BF25_RS25785	COG0460	homoserine dehydrogenase
BF25_RS25795	COG1609	Transcriptional regulator
BF25_RS25800	COG2755	lipolytic protein G-D-S-L family
BF25_RS25805	COG1131	(ABC) transporter
BF25_RS25810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF25_RS25820	COG2814	Major facilitator Superfamily
BF25_RS25825	COG0561	phosphatase activity
BF25_RS25830	COG2233	PERMEase
BF25_RS25845	COG2363	Small membrane protein
BF25_RS25855	COG3773	Cell wall hydrolase
BF25_RS25870	COG0280	phosphate acetyltransferase
BF25_RS25875	COG0095	Lipoate-protein ligase
BF25_RS25895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS25900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS25905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF25_RS25910	COG1120	ATPase activity
BF25_RS25915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF25_RS25920	COG1078	dGTPase activity
BF25_RS25930	COG1994	Peptidase M50
BF25_RS25940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF25_RS25945	COG0584	glycerophosphoryl diester phosphodiesterase
BF25_RS25950	COG0789	Transcriptional regulator
BF25_RS25955	COG2814	Major facilitator Superfamily
BF25_RS25965	COG0010	Belongs to the arginase family
BF25_RS25985	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF25_RS25990	COG4506	Protein conserved in bacteria
BF25_RS25995	COG0018	arginyl-trna synthetase
BF25_RS26000	COG1595	DNA-templated transcription, initiation
BF25_RS26020	COG2234	aminopeptidase activity
BF25_RS26040	COG0024	Methionine aminopeptidase
BF25_RS26045	COG1131	(ABC) transporter
BF25_RS26050	COG0842	Transport permease protein
BF25_RS26055	COG4585	Histidine kinase
BF25_RS26060	COG2197	response regulator
BF25_RS26075	COG3300	MHYT domain
BF25_RS26075	COG5001	Diguanylate cyclase
BF25_RS26085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF25_RS26090	COG0247	lactate metabolic process
BF25_RS26090	COG2181	nitrate reductase activity
BF25_RS26095	COG0183	Belongs to the thiolase family
BF25_RS26100	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF25_RS26105	COG1960	acyl-CoA dehydrogenase activity
BF25_RS26110	COG1960	acyl-CoA dehydrogenase activity
BF25_RS26120	COG3343	RNA polymerase activity
BF25_RS26130	COG4821	SIS domain
BF25_RS26150	COG1494	fructose-1,6-bisphosphatase
BF25_RS26155	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF25_RS26175	COG2890	protein-(glutamine-N5) methyltransferase activity
BF25_RS26190	COG0009	L-threonylcarbamoyladenylate synthase
BF25_RS26205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF25_RS26210	COG2259	Doxx family
BF25_RS26215	COG2190	(PTS) system
BF25_RS26225	COG0698	ribose 5-phosphate isomerase
BF25_RS26260	COG0356	it plays a direct role in the translocation of protons across the membrane
BF25_RS26310	COG5001	Diguanylate cyclase
BF25_RS26310	COG3300	MHYT domain
BF25_RS26325	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF25_RS26330	COG0649	NAD binding
BF25_RS26345	COG0839	Belongs to the complex I subunit 6 family
BF25_RS26355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF25_RS26360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF25_RS26365	COG1007	ATP synthesis coupled electron transport
BF25_RS26370	COG4836	Membrane
BF25_RS26385	COG2385	sporulation resulting in formation of a cellular spore
BF25_RS26390	COG4555	ABC transporter
BF25_RS26395	COG3279	Response regulator of the LytR AlgR family
BF25_RS26410	COG0739	heme binding
BF25_RS26425	COG1609	Transcriptional regulator
BF25_RS26470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF25_RS26475	COG1682	transport, permease protein
BF25_RS26480	COG1134	teichoic acid transport
BF25_RS26485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF25_RS26500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF25_RS26505	COG0745	RESPONSE REGULATOR receiver
BF25_RS26510	COG5002	protein histidine kinase activity
BF25_RS26545	COG1136	(ABC) transporter
BF25_RS26550	COG0577	efflux transmembrane transporter activity
BF25_RS26590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF25_RS26595	COG4715	Zinc finger, swim domain protein
BF25_RS26620	COG1388	LysM domain
BF25_RS26620	COG3584	3D domain protein
BF25_RS26625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF25_RS26645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS26660	COG1368	sulfuric ester hydrolase activity
BF25_RS26670	COG2389	metal-binding protein
BF25_RS26680	COG1620	l-lactate permease
BF25_RS26690	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF25_RS26695	COG1294	oxidase, subunit
BF25_RS26700	COG1271	oxidase subunit
BF25_RS26720	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF25_RS26725	COG0583	DNA-binding transcription factor activity
BF25_RS26730	COG1511	domain protein
BF25_RS26735	COG0346	lactoylglutathione lyase activity
BF25_RS26745	COG1301	dicarboxylic acid transport
BF25_RS26750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF25_RS26760	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF25_RS26765	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF25_RS26770	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF25_RS26780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF25_RS26785	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF25_RS26790	COG1486	melibiose metabolic process
BF25_RS26795	COG3394	polysaccharide catabolic process
BF25_RS26810	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF25_RS26810	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF25_RS26820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF25_RS26825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF25_RS26830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF25_RS26835	COG1316	TRANSCRIPTIONal
BF25_RS26840	COG1739	Uncharacterized protein family UPF0029
BF25_RS26845	COG1307	EDD domain protein, DegV family
BF25_RS26855	COG1733	regulation of RNA biosynthetic process
BF25_RS26860	COG1388	LysM domain
BF25_RS26860	COG0791	NLP P60 protein
BF25_RS26865	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF25_RS26870	COG1040	competence protein
BF25_RS26875	COG1278	Cold shock
BF25_RS26880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF25_RS26885	COG0653	protein targeting
BF25_RS26890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF25_RS26905	COG2884	Cell division ATP-binding protein ftsE
BF25_RS26910	COG2177	Part of the ABC transporter FtsEX involved in
BF25_RS26915	COG3409	Peptidoglycan-binding domain 1 protein
BF25_RS26915	COG0793	Belongs to the peptidase S41A family
BF25_RS26920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF25_RS26925	COG1132	(ABC) transporter
BF25_RS26935	COG0488	(ABC) transporter
BF25_RS26940	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF25_RS26950	COG0583	DNA-binding transcription factor activity
BF25_RS26980	COG0789	Transcriptional regulator
BF25_RS27000	COG0556	nucleotide-excision repair
BF25_RS27005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF25_RS27015	COG1950	PFAM Membrane protein of
BF25_RS27035	COG0110	maltose O-acetyltransferase activity
BF25_RS27040	COG0457	Tetratricopeptide repeat
BF25_RS27045	COG0492	ferredoxin-NADP+ reductase activity
BF25_RS27055	COG1051	belongs to the nudix hydrolase family
BF25_RS27065	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF25_RS27075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF25_RS27080	COG0740	serine-type endopeptidase activity
BF25_RS27085	COG2323	membrane
BF25_RS27100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF25_RS27125	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF25_RS27140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF25_RS27150	COG0149	triose-phosphate isomerase activity
BF25_RS27155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF25_RS27165	COG4974	Belongs to the 'phage' integrase family
BF25_RS27190	COG4695	Portal protein
BF25_RS27290	COG1346	cytolysis
BF25_RS27295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF25_RS27300	COG1647	Serine aminopeptidase, S33
BF25_RS27305	COG0557	exoribonuclease II activity
BF25_RS27355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF25_RS27370	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF25_RS27375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF25_RS27385	COG0840	transmembrane signaling receptor activity
BF25_RS27385	COG3290	protein histidine kinase activity
BF25_RS27395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF25_RS27400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF25_RS27405	COG1252	NADH dehydrogenase
BF25_RS27415	COG1733	regulation of RNA biosynthetic process
BF25_RS27420	COG2814	Major facilitator Superfamily
BF25_RS27425	COG0656	L-ascorbic acid biosynthetic process
BF25_RS27440	COG2910	NAD(P)H-binding
BF25_RS27445	COG1115	amino acid carrier protein
BF25_RS27450	COG1115	amino acid carrier protein
BF25_RS27455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS27460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF25_RS27470	COG2311	Membrane
BF25_RS27485	COG1611	Belongs to the LOG family
BF25_RS27500	COG0783	Belongs to the Dps family
BF25_RS27505	COG1115	amino acid carrier protein
BF25_RS27515	COG0490	domain, Protein
BF25_RS27520	COG0475	glutathione-regulated potassium exporter activity
BF25_RS27535	COG1741	Belongs to the pirin family
BF25_RS27540	COG3227	Zinc metalloprotease (Elastase)
BF25_RS27545	COG2151	metal-sulfur cluster biosynthetic enzyme
BF25_RS27570	COG5002	protein histidine kinase activity
BF25_RS27575	COG0745	RESPONSE REGULATOR receiver
BF25_RS27580	COG1376	ErfK ybiS ycfS ynhG family protein
BF25_RS27590	COG0586	Pfam SNARE associated Golgi protein
BF25_RS27625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS27635	COG0706	membrane insertase activity
BF25_RS27645	COG0531	amino acid
BF25_RS27650	COG2814	Major facilitator Superfamily
BF25_RS27670	COG0840	transmembrane signaling receptor activity
BF25_RS27675	COG0011	TIGRFAM Protein of
BF25_RS27690	COG1686	Belongs to the peptidase S11 family
BF25_RS27700	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF25_RS27700	COG1024	Enoyl-CoA hydratase
BF25_RS27705	COG0183	Belongs to the thiolase family
BF25_RS27715	COG1960	acyl-CoA dehydrogenase activity
BF25_RS27720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS27725	COG1309	transcriptional regulator
BF25_RS27750	COG0039	L-malate dehydrogenase activity
BF25_RS27800	COG1393	Belongs to the ArsC family
BF25_RS27810	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF25_RS27815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF25_RS27830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF25_RS27835	COG2011	ABC-type metal ion transport system permease component
BF25_RS27840	COG1464	Belongs to the NlpA lipoprotein family
BF25_RS27845	COG1464	Belongs to the NlpA lipoprotein family
BF25_RS27850	COG0396	ATPase activity
BF25_RS27855	COG0719	Fe-S assembly protein
BF25_RS27860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF25_RS27865	COG0822	iron-sulfur transferase activity
BF25_RS27870	COG0719	Fe-S assembly protein
BF25_RS27885	COG1695	Transcriptional regulator
BF25_RS27895	COG0737	Belongs to the 5'-nucleotidase family
BF25_RS27900	COG3377	Domain of unknown function (DUF1805)
BF25_RS27910	COG0739	heme binding
BF25_RS27935	COG4377	Putative membrane peptidase family (DUF2324)
BF25_RS27940	COG0789	Transcriptional regulator
BF25_RS27950	COG4470	Protein conserved in bacteria
BF25_RS27970	COG1494	fructose-1,6-bisphosphatase
BF25_RS27975	COG2445	Protein of unknown function DUF86
BF25_RS27985	COG0647	UMP catabolic process
BF25_RS27990	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF25_RS28005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF25_RS28010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF25_RS28020	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF25_RS28025	COG4837	Protein of unknown function (DUF1462)
BF25_RS28065	COG2824	Alkylphosphonate utilization operon protein PhnA
BF25_RS28070	COG0390	transport system, permease component
BF25_RS28085	COG1252	NADH dehydrogenase
BF25_RS28100	COG0316	Belongs to the HesB IscA family
BF25_RS28120	COG1683	Conserved Protein
BF25_RS28135	COG3708	Transcriptional regulator
BF25_RS28150	COG1252	NADH dehydrogenase
BF25_RS28165	COG3584	3D domain protein
BF25_RS28180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF25_RS28185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF25_RS28195	COG1268	BioY protein
BF25_RS28205	COG2050	protein possibly involved in aromatic compounds catabolism
BF25_RS28225	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF25_RS28230	COG5018	Exonuclease
BF25_RS28250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF25_RS28260	COG2267	carboxylic ester hydrolase activity
BF25_RS28265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF25_RS28270	COG1522	sequence-specific DNA binding
BF25_RS28275	COG0436	Aminotransferase
BF25_RS28280	COG1098	S1 RNA binding domain
BF25_RS28285	COG2155	Conserved Protein
BF25_RS28295	COG0166	Belongs to the GPI family
BF25_RS28305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF25_RS28310	COG1285	pathogenesis
BF25_RS28345	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF25_RS28455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF25_RS28460	COG0297	glycogen (starch) synthase activity
BF25_RS28465	COG0058	SHG alpha-glucan phosphorylase activity
BF25_RS28490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF25_RS28495	COG1575	Belongs to the MenA family. Type 1 subfamily
BF25_RS28500	COG1169	isochorismate synthase
BF25_RS28505	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF25_RS28510	COG0596	Alpha beta hydrolase
BF25_RS28515	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF25_RS28525	COG4948	Mandelate Racemase Muconate Lactonizing
BF25_RS28555	COG3964	amidohydrolase
BF25_RS28575	COG2188	Transcriptional regulator
BF25_RS28595	COG1136	(ABC) transporter
BF25_RS28600	COG0577	efflux transmembrane transporter activity
BF25_RS28620	COG2205	protein histidine kinase activity
BF25_RS28625	COG0745	RESPONSE REGULATOR receiver
BF25_RS28630	COG2207	Transcriptional regulator
BF25_RS28630	COG3708	Transcriptional regulator
BF25_RS28635	COG1136	(ABC) transporter
BF25_RS28640	COG0577	efflux transmembrane transporter activity
BF25_RS28650	COG0586	Pfam SNARE associated Golgi protein
BF25_RS28685	COG1597	lipid kinase activity
BF25_RS28715	COG0745	RESPONSE REGULATOR receiver
BF25_RS28720	COG5002	protein histidine kinase activity
BF25_RS28755	COG1842	Phage shock protein A
BF25_RS28780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF25_RS28800	COG1294	oxidase, subunit
BF25_RS28805	COG1271	oxidase subunit
BF25_RS28810	COG0288	reversible hydration of carbon dioxide
BF25_RS28840	COG0494	nUDIX hydrolase
BF25_RS28865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF25_RS28870	COG1116	anion transmembrane transporter activity
BF25_RS28875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF25_RS28895	COG2267	carboxylic ester hydrolase activity
BF25_RS28900	COG4191	Histidine kinase
BF25_RS28905	COG5002	protein histidine kinase activity
BF25_RS28910	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF25_RS28965	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF25_RS28975	COG0438	transferase activity, transferring glycosyl groups
BF25_RS28980	COG0671	phosphoesterase, PA-phosphatase related
BF25_RS28985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF25_RS28990	COG2267	carboxylic ester hydrolase activity
BF25_RS29010	COG1794	racemase activity, acting on amino acids and derivatives
BF25_RS29020	COG1131	(ABC) transporter
BF25_RS29025	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF25_RS29030	COG1242	4 iron, 4 sulfur cluster binding
BF25_RS29050	COG1136	(ABC) transporter
BF25_RS29060	COG0582	viral genome integration into host DNA
BF25_RS29065	COG0490	domain, Protein
BF25_RS29070	COG0475	glutathione-regulated potassium exporter activity
BF25_RS29075	COG2814	Major facilitator Superfamily
BF25_RS29120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF25_RS29130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF25_RS29155	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF25_RS29165	COG0303	'Molybdopterin
BF25_RS29170	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF25_RS29175	COG0314	molybdopterin synthase activity
BF25_RS29190	COG4975	Glucose uptake
BF25_RS29200	COG1329	Transcriptional regulator
BF25_RS29220	COG3832	glyoxalase III activity
BF25_RS29230	COG2814	Major facilitator Superfamily
BF25_RS29235	COG2081	HI0933 family
BF25_RS29240	COG2244	polysaccharide biosynthetic process
BF25_RS29245	COG1187	pseudouridine synthase activity
BF25_RS29250	COG1349	DNA-binding transcription factor activity
BF25_RS29255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF25_RS29260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF25_RS29275	COG1523	belongs to the glycosyl hydrolase 13 family
BF25_RS29280	COG0510	thiamine kinase activity
BF25_RS29295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF25_RS29305	COG1363	Peptidase, m42
BF25_RS29485	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF25_RS29575	COG1719	4-vinyl reductase, 4VR
BF25_RS29640	COG1360	Flagellar Motor Protein
BF25_RS29645	COG1360	Flagellar Motor Protein
BF25_RS29780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF25_RS30000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF25_RS30005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF25_RS30015	COG0456	acetyltransferase
BF25_RS30065	COG1846	Transcriptional regulator
BF25_RS30080	COG4191	Histidine kinase
BF25_RS30085	COG4191	Histidine kinase
BF25_RS30100	COG1113	amino acid transport
BF25_RS30105	COG1113	amino acid transport
BF25_RS30305	COG0488	(ABC) transporter
BF25_RS30310	COG0488	(ABC) transporter
BF25_RS30335	COG0768	penicillin binding
BF25_RS30580	COG1131	(ABC) transporter
BF25_RS30630	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF25_RS30660	COG2198	Histidine kinase
BF25_RS30660	COG0643	Histidine kinase
BF25_RS30865	COG2376	Dihydroxyacetone kinase
BF25_RS30890	COG0322	excinuclease ABC activity
BF25_RS30920	COG3409	Peptidoglycan-binding domain 1 protein
BF25_RS30920	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF25_RS31035	COG0003	Pfam Anion-transporting ATPase
BF25_RS31040	COG0003	Pfam Anion-transporting ATPase
BF25_RS31145	COG2203	Gaf domain
BF25_RS31145	COG4585	Histidine kinase
BF25_RS31150	COG4585	Histidine kinase
BF25_RS31150	COG2203	Gaf domain
BF25_RS31335	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668