locus-tag	class	description
BF89_RS00605	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS00695	COG0768	penicillin binding
BF89_RS00850	COG1649	PFAM Uncharacterised BCR, COG1649
BF89_RS01015	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF89_RS01135	COG0596	Alpha beta hydrolase
BF89_RS01180	COG1115	amino acid carrier protein
BF89_RS01305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF89_RS01310	COG1024	Enoyl-CoA hydratase
BF89_RS01315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF89_RS01320	COG0511	ligase activity, forming carbon-carbon bonds
BF89_RS01325	COG0439	Biotin carboxylase
BF89_RS01330	COG1960	acyl-CoA dehydrogenase activity
BF89_RS01345	COG1309	transcriptional regulator
BF89_RS01355	COG1131	(ABC) transporter
BF89_RS01370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_RS01385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS01400	COG0488	(ABC) transporter
BF89_RS01405	COG1309	transcriptional regulator
BF89_RS01425	COG1876	peptidase activity
BF89_RS01440	COG1476	TRANSCRIPTIONal
BF89_RS01455	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS01475	COG0191	fructose-bisphosphate aldolase activity
BF89_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS01500	COG0673	inositol 2-dehydrogenase activity
BF89_RS01505	COG2814	Major facilitator Superfamily
BF89_RS01510	COG1609	Transcriptional regulator
BF89_RS01515	COG0671	phosphoesterase, PA-phosphatase related
BF89_RS01520	COG2367	Beta-lactamase
BF89_RS01525	COG0768	penicillin binding
BF89_RS01530	COG0768	penicillin binding
BF89_RS01540	COG1595	DNA-templated transcription, initiation
BF89_RS01555	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF89_RS01595	COG1846	Transcriptional regulator
BF89_RS01600	COG3961	Belongs to the TPP enzyme family
BF89_RS01605	COG2226	methyltransferase
BF89_RS01615	COG0500	methyltransferase
BF89_RS01615	COG3615	Tellurite resistance protein tehB
BF89_RS01620	COG1136	(ABC) transporter
BF89_RS01620	COG0577	efflux transmembrane transporter activity
BF89_RS01640	COG1309	transcriptional regulator
BF89_RS01670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS01690	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF89_RS01695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF89_RS01700	COG2971	BadF BadG BcrA BcrD
BF89_RS01725	COG1649	PFAM Uncharacterised BCR, COG1649
BF89_RS01750	COG1595	DNA-templated transcription, initiation
BF89_RS01755	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BF89_RS01780	COG1396	sequence-specific DNA binding
BF89_RS01800	COG1132	(ABC) transporter
BF89_RS01805	COG1132	(ABC) transporter
BF89_RS01820	COG2258	MOSC domain
BF89_RS01825	COG0583	DNA-binding transcription factor activity
BF89_RS01840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF89_RS01845	COG0583	DNA-binding transcription factor activity
BF89_RS01890	COG0561	phosphatase activity
BF89_RS01895	COG0010	Belongs to the arginase family
BF89_RS01910	COG1278	Cold shock
BF89_RS01920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS01930	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF89_RS01960	COG1247	-acetyltransferase
BF89_RS01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS02040	COG2226	methyltransferase
BF89_RS02060	COG2814	Major facilitator Superfamily
BF89_RS02065	COG0596	Alpha beta hydrolase
BF89_RS02080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF89_RS02085	COG1187	pseudouridine synthase activity
BF89_RS02090	COG2329	Antibiotic biosynthesis monooxygenase
BF89_RS02120	COG2318	DinB family
BF89_RS02130	COG0776	regulation of translation
BF89_RS02145	COG2814	Major facilitator Superfamily
BF89_RS02150	COG3251	PFAM MbtH domain protein
BF89_RS02160	COG3433	isochorismatase activity
BF89_RS02160	COG1535	isochorismatase
BF89_RS02165	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF89_RS02170	COG1169	isochorismate synthase
BF89_RS02175	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS02180	COG2223	nitrite transmembrane transporter activity
BF89_RS02210	COG0419	ATPase involved in DNA repair
BF89_RS02215	COG0420	3'-5' exonuclease activity
BF89_RS02230	COG1024	Enoyl-CoA hydratase
BF89_RS02235	COG1280	lysine exporter protein (LysE YggA)
BF89_RS02245	COG2084	Dehydrogenase
BF89_RS02250	COG1960	acyl-CoA dehydrogenase activity
BF89_RS02255	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF89_RS02260	COG2079	MmgE PrpD family protein
BF89_RS02265	COG0372	Belongs to the citrate synthase family
BF89_RS02270	COG4841	protein insertion into membrane
BF89_RS02275	COG2814	Major facilitator Superfamily
BF89_RS02280	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF89_RS02280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_RS02320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF89_RS02410	COG1715	Restriction endonuclease
BF89_RS02410	COG1787	Restriction endonuclease
BF89_RS02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_RS02445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF89_RS02450	COG0671	phosphoesterase, PA-phosphatase related
BF89_RS02455	COG4326	sporulation control protein
BF89_RS02495	COG1509	lysine 2,3-aminomutase activity
BF89_RS02500	COG3829	transcription factor binding
BF89_RS02505	COG0456	acetyltransferase
BF89_RS02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF89_RS02515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF89_RS02520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF89_RS02525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF89_RS02540	COG5506	Protein of unknown function (DUF1694)
BF89_RS02545	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS02550	COG1253	flavin adenine dinucleotide binding
BF89_RS02585	COG1174	glycine betaine transport
BF89_RS02590	COG1125	glycine betaine transport
BF89_RS02590	COG0517	IMP dehydrogenase activity
BF89_RS02620	COG1070	Carbohydrate kinase
BF89_RS02625	COG1070	Carbohydrate kinase
BF89_RS02655	COG1064	alcohol dehydrogenase
BF89_RS02660	COG1737	Transcriptional regulator
BF89_RS02670	COG2197	response regulator
BF89_RS02675	COG2203	Gaf domain
BF89_RS02675	COG4585	Histidine kinase
BF89_RS02680	COG0668	transmembrane transport
BF89_RS02715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_RS02720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS02735	COG0367	asparagine synthase
BF89_RS02740	COG0071	Belongs to the small heat shock protein (HSP20) family
BF89_RS02745	COG1999	signal sequence binding
BF89_RS02750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF89_RS02755	COG1307	EDD domain protein, DegV family
BF89_RS02765	COG0805	protein transport
BF89_RS02775	COG1272	protein, Hemolysin III
BF89_RS02780	COG0204	Acyl-transferase
BF89_RS02785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF89_RS02790	COG0768	penicillin binding
BF89_RS02805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_RS02825	COG0546	phosphoglycolate phosphatase activity
BF89_RS02835	COG4473	ABC transporter
BF89_RS02840	COG1131	(ABC) transporter
BF89_RS02855	COG0456	acetyltransferase
BF89_RS02865	COG1794	racemase activity, acting on amino acids and derivatives
BF89_RS02870	COG1454	alcohol dehydrogenase
BF89_RS02875	COG2610	gluconate transmembrane transporter activity
BF89_RS02900	COG0733	neurotransmitter:sodium symporter activity
BF89_RS02915	COG5002	protein histidine kinase activity
BF89_RS02915	COG3850	Histidine kinase
BF89_RS02920	COG0745	RESPONSE REGULATOR receiver
BF89_RS02925	COG0471	metal ion transport
BF89_RS02930	COG1929	Belongs to the glycerate kinase type-1 family
BF89_RS03025	COG1674	ftsk spoiiie
BF89_RS03045	COG0017	Asparaginyl-tRNA synthetase
BF89_RS03050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF89_RS03065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF89_RS03090	COG0018	arginyl-trna synthetase
BF89_RS03095	COG2521	methyltransferase
BF89_RS03095	COG2136	Putative SAM-dependent methyltransferase
BF89_RS03110	COG1413	lyase activity
BF89_RS03115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF89_RS03130	COG0629	single-stranded DNA binding
BF89_RS03145	COG0488	(ABC) transporter
BF89_RS03150	COG1418	mRNA catabolic process
BF89_RS03165	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_RS03180	COG2359	stage V sporulation protein S
BF89_RS03215	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF89_RS03220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF89_RS03225	COG2146	nitrite reductase [NAD(P)H] activity
BF89_RS03230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF89_RS03230	COG1587	Uroporphyrinogen-III synthase
BF89_RS03240	COG1648	precorrin-2 dehydrogenase activity
BF89_RS03255	COG2223	nitrite transmembrane transporter activity
BF89_RS03265	COG0314	molybdopterin synthase activity
BF89_RS03270	COG0303	'Molybdopterin
BF89_RS03275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_RS03280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF89_RS03285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF89_RS03305	COG2181	nitrate reductase activity
BF89_RS03310	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF89_RS03315	COG1140	nitrate reductase beta subunit
BF89_RS03320	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF89_RS03335	COG0714	Associated with various cellular activities
BF89_RS03340	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF89_RS03345	COG1305	Transglutaminase-like
BF89_RS03350	COG0386	Belongs to the glutathione peroxidase family
BF89_RS03375	COG1595	DNA-templated transcription, initiation
BF89_RS03380	COG0604	alcohol dehydrogenase
BF89_RS03390	COG0346	lactoylglutathione lyase activity
BF89_RS03395	COG1082	Xylose isomerase domain protein TIM barrel
BF89_RS03440	COG3874	Sporulation protein YtfJ
BF89_RS03490	COG0456	acetyltransferase
BF89_RS03515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS03520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS03525	COG1819	glycosyl
BF89_RS03540	COG4106	trans-aconitate 2-methyltransferase activity
BF89_RS03545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF89_RS03555	COG0561	phosphatase activity
BF89_RS03575	COG2211	Major facilitator Superfamily
BF89_RS03580	COG0154	amidase activity
BF89_RS03590	COG1876	peptidase activity
BF89_RS03600	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_RS03620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_RS03625	COG1114	Component of the transport system for branched-chain amino acids
BF89_RS03640	COG1253	flavin adenine dinucleotide binding
BF89_RS03645	COG2839	Protein conserved in bacteria
BF89_RS03650	COG0702	epimerase
BF89_RS03665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_RS03670	COG1607	acyl-coa hydrolase
BF89_RS03675	COG3689	TIGRFAM TIGR03943 family protein
BF89_RS03680	COG0701	Predicted permease
BF89_RS03690	COG2244	polysaccharide biosynthetic process
BF89_RS03695	COG0586	Pfam SNARE associated Golgi protein
BF89_RS03700	COG1051	belongs to the nudix hydrolase family
BF89_RS03705	COG5337	Spore coat protein CotH
BF89_RS03715	COG0406	alpha-ribazole phosphatase activity
BF89_RS03730	COG4166	transmembrane transport
BF89_RS03740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF89_RS03750	COG0702	epimerase
BF89_RS03760	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF89_RS03760	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF89_RS03825	COG0456	acetyltransferase
BF89_RS03830	COG0523	cobalamin synthesis protein
BF89_RS03835	COG4989	oxidoreductase activity
BF89_RS03845	COG1231	oxidoreductase activity
BF89_RS03855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF89_RS03870	COG0783	Belongs to the Dps family
BF89_RS03875	COG3949	Membrane
BF89_RS03895	COG0840	transmembrane signaling receptor activity
BF89_RS03920	COG2814	Major facilitator Superfamily
BF89_RS03925	COG0667	Aldo Keto reductase
BF89_RS03930	COG0640	Transcriptional regulator
BF89_RS03935	COG1404	Belongs to the peptidase S8 family
BF89_RS03940	COG2002	toxin-antitoxin pair type II binding
BF89_RS03945	COG0577	efflux transmembrane transporter activity
BF89_RS03980	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF89_RS03990	COG1279	arginine transmembrane transporter activity
BF89_RS03995	COG2814	Major facilitator Superfamily
BF89_RS04005	COG1082	Xylose isomerase domain protein TIM barrel
BF89_RS04015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF89_RS04035	COG1247	-acetyltransferase
BF89_RS04040	COG1285	pathogenesis
BF89_RS04055	COG5002	protein histidine kinase activity
BF89_RS04060	COG0745	RESPONSE REGULATOR receiver
BF89_RS04070	COG1316	TRANSCRIPTIONal
BF89_RS04095	COG0460	homoserine dehydrogenase
BF89_RS04130	COG0300	oxidoreductase activity
BF89_RS04145	COG0745	RESPONSE REGULATOR receiver
BF89_RS04150	COG1132	(ABC) transporter
BF89_RS04155	COG1132	(ABC) transporter
BF89_RS04165	COG1388	LysM domain
BF89_RS04165	COG0791	NLP P60 protein
BF89_RS04180	COG1686	Belongs to the peptidase S11 family
BF89_RS04200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF89_RS04205	COG4988	ABC transporter
BF89_RS04210	COG1294	oxidase, subunit
BF89_RS04215	COG1271	oxidase subunit
BF89_RS04225	COG1846	Transcriptional regulator
BF89_RS04235	COG1942	4-Oxalocrotonate Tautomerase
BF89_RS04245	COG0583	DNA-binding transcription factor activity
BF89_RS04265	COG0411	ABC transporter
BF89_RS04275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_RS04280	COG2030	dehydratase
BF89_RS04285	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_RS04300	COG0523	cobalamin synthesis protein
BF89_RS04305	COG1231	oxidoreductase activity
BF89_RS04315	COG0628	permease
BF89_RS04330	COG0778	Nitroreductase
BF89_RS04335	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF89_RS04340	COG1959	2 iron, 2 sulfur cluster binding
BF89_RS04345	COG0583	DNA-binding transcription factor activity
BF89_RS04350	COG0697	spore germination
BF89_RS04360	COG4549	nuclear export factor GLE1
BF89_RS04365	COG1276	copper resistance
BF89_RS04365	COG2372	response to copper ion
BF89_RS04380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF89_RS04395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF89_RS04410	COG2132	Multicopper oxidase
BF89_RS04415	COG0006	proline dipeptidase activity
BF89_RS04435	COG4224	UPF0291 protein
BF89_RS04450	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF89_RS04455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS04465	COG2390	Transcriptional regulator
BF89_RS04500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF89_RS04515	COG1914	H( )-stimulated, divalent metal cation uptake system
BF89_RS04535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS04540	COG0535	radical SAM domain protein
BF89_RS04565	COG4166	transmembrane transport
BF89_RS04570	COG1073	alpha beta
BF89_RS04590	COG0427	acetyl-CoA hydrolase
BF89_RS04595	COG3279	Response regulator of the LytR AlgR family
BF89_RS04605	COG3384	dioxygenase
BF89_RS04635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF89_RS04645	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF89_RS04650	COG0440	acetolactate synthase activity
BF89_RS04655	COG0028	Belongs to the TPP enzyme family
BF89_RS04660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_RS04670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF89_RS04685	COG2084	Dehydrogenase
BF89_RS04700	COG2323	membrane
BF89_RS04705	COG5566	PFAM Mor transcription activator
BF89_RS04715	COG0733	neurotransmitter:sodium symporter activity
BF89_RS04720	COG2244	polysaccharide biosynthetic process
BF89_RS04750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF89_RS04760	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_RS04765	COG0477	Major facilitator Superfamily
BF89_RS04775	COG1966	Carbon starvation protein
BF89_RS04790	COG2814	Major facilitator Superfamily
BF89_RS04800	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_RS04865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF89_RS04870	COG0784	Response regulator, receiver
BF89_RS04875	COG4191	Histidine kinase
BF89_RS04880	COG0281	malic enzyme
BF89_RS04885	COG1027	Aspartate ammonia-lyase
BF89_RS04895	COG0528	UMP kinase activity
BF89_RS04900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_RS04915	COG1131	(ABC) transporter
BF89_RS04950	COG2733	membrane
BF89_RS04985	COG0785	Cytochrome C biogenesis protein
BF89_RS05005	COG3340	Belongs to the peptidase S51 family
BF89_RS05035	COG0114	fumarate hydratase activity
BF89_RS05040	COG1757	Na H antiporter
BF89_RS05045	COG0438	transferase activity, transferring glycosyl groups
BF89_RS05045	COG1216	Glycosyl transferase, family 2
BF89_RS05055	COG0701	Predicted permease
BF89_RS05060	COG0523	cobalamin synthesis protein
BF89_RS05065	COG0697	spore germination
BF89_RS05070	COG1802	Transcriptional regulator
BF89_RS05100	COG0367	asparagine synthase
BF89_RS05140	COG1686	Belongs to the peptidase S11 family
BF89_RS05165	COG1234	tRNA 3'-trailer cleavage
BF89_RS05175	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF89_RS05180	COG3842	ATPase activity
BF89_RS05210	COG2329	Antibiotic biosynthesis monooxygenase
BF89_RS05230	COG1309	transcriptional regulator
BF89_RS05255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF89_RS05260	COG4786	Flagellar basal body rod
BF89_RS05265	COG1419	protein localization to endoplasmic reticulum
BF89_RS05270	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF89_RS05275	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF89_RS05285	COG1987	bacterial-type flagellum assembly
BF89_RS05290	COG1338	Plays a role in the flagellum-specific transport system
BF89_RS05300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_RS05300	COG1776	CheC inhibitor of MCP methylation
BF89_RS05315	COG0741	lytic transglycosylase activity
BF89_RS05320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF89_RS05345	COG0457	Tetratricopeptide repeat
BF89_RS05345	COG0463	Glycosyl transferase, family 2
BF89_RS05375	COG0463	Glycosyl transferase, family 2
BF89_RS05385	COG0784	Response regulator, receiver
BF89_RS05385	COG0835	chemotaxis
BF89_RS05425	COG1157	protein secretion by the type III secretion system
BF89_RS05435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_RS05445	COG1766	The M ring may be actively involved in energy transduction
BF89_RS05455	COG1558	bacterial-type flagellum-dependent cell motility
BF89_RS05460	COG1815	bacterial-type flagellum-dependent cell motility
BF89_RS05485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF89_RS05490	COG1256	bacterial-type flagellum assembly
BF89_RS05510	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF89_RS05525	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF89_RS05525	COG1776	CheC inhibitor of MCP methylation
BF89_RS05535	COG2201	protein-glutamate methylesterase activity
BF89_RS05540	COG1360	Flagellar Motor Protein
BF89_RS05545	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF89_RS05555	COG1923	regulation of RNA biosynthetic process
BF89_RS05610	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF89_RS05615	COG2323	membrane
BF89_RS05625	COG4978	Transcriptional regulator
BF89_RS05625	COG0789	Transcriptional regulator
BF89_RS05630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF89_RS05635	COG0475	glutathione-regulated potassium exporter activity
BF89_RS05645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF89_RS05650	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_RS05655	COG3162	membrane
BF89_RS05670	COG1280	lysine exporter protein (LysE YggA)
BF89_RS05710	COG0328	RNA-DNA hybrid ribonuclease activity
BF89_RS05735	COG0454	-acetyltransferase
BF89_RS05755	COG1215	transferase activity, transferring glycosyl groups
BF89_RS05770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF89_RS05795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF89_RS05810	COG0754	glutathionylspermidine amidase activity
BF89_RS05835	COG0456	acetyltransferase
BF89_RS05845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF89_RS05850	COG2311	Membrane
BF89_RS05855	COG2233	PERMEase
BF89_RS05865	COG0024	Methionine aminopeptidase
BF89_RS05870	COG3173	Aminoglycoside phosphotransferase
BF89_RS05880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF89_RS05885	COG1199	ATP-dependent helicase activity
BF89_RS05895	COG0116	Belongs to the methyltransferase superfamily
BF89_RS05945	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF89_RS05945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_RS05955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF89_RS05960	COG3935	DnaD domain protein
BF89_RS06020	COG0438	transferase activity, transferring glycosyl groups
BF89_RS06025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF89_RS06040	COG1694	Mazg nucleotide pyrophosphohydrolase
BF89_RS06045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS06055	COG2738	Putative neutral zinc metallopeptidase
BF89_RS06070	COG4347	Protein of unknown function (DUF1405)
BF89_RS06080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF89_RS06100	COG0457	Tetratricopeptide repeat
BF89_RS06105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF89_RS06125	COG0142	geranyltranstransferase activity
BF89_RS06135	COG0142	geranyltranstransferase activity
BF89_RS06150	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF89_RS06220	COG0252	asparaginase activity
BF89_RS06225	COG0492	ferredoxin-NADP+ reductase activity
BF89_RS06245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF89_RS06250	COG4862	establishment of competence for transformation
BF89_RS06270	COG1266	CAAX protease self-immunity
BF89_RS06275	COG0514	ATP-dependent DNA helicase (RecQ)
BF89_RS06280	COG4955	Helix-turn-helix domain
BF89_RS06285	COG1141	Ferredoxin
BF89_RS06290	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF89_RS06305	COG2096	Adenosyltransferase
BF89_RS06310	COG5002	protein histidine kinase activity
BF89_RS06315	COG0745	RESPONSE REGULATOR receiver
BF89_RS06320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF89_RS06325	COG1333	cytochrome c biogenesis protein
BF89_RS06335	COG1187	pseudouridine synthase activity
BF89_RS06340	COG0700	Nucleoside recognition
BF89_RS06345	COG2715	membrane protein required for spore maturation
BF89_RS06350	COG1686	Belongs to the peptidase S11 family
BF89_RS06355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF89_RS06370	COG0392	lysyltransferase activity
BF89_RS06370	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF89_RS06390	COG5002	protein histidine kinase activity
BF89_RS06395	COG0582	viral genome integration into host DNA
BF89_RS06405	COG1801	Protein of unknown function DUF72
BF89_RS06410	COG3852	Histidine kinase
BF89_RS06425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_RS06430	COG1392	Phosphate transport regulator
BF89_RS06435	COG0306	phosphate transporter
BF89_RS06440	COG0730	response to heat
BF89_RS06460	COG1017	nitric oxide dioxygenase activity
BF89_RS06460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF89_RS06485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF89_RS06495	COG1114	Component of the transport system for branched-chain amino acids
BF89_RS06505	COG2197	response regulator
BF89_RS06510	COG4585	Histidine kinase
BF89_RS06515	COG4758	membrane
BF89_RS06530	COG1757	Na H antiporter
BF89_RS06550	COG0733	neurotransmitter:sodium symporter activity
BF89_RS06560	COG1648	precorrin-2 dehydrogenase activity
BF89_RS06580	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF89_RS06585	COG0529	Catalyzes the synthesis of activated sulfate
BF89_RS06605	COG0019	diaminopimelate decarboxylase activity
BF89_RS06615	COG1368	sulfuric ester hydrolase activity
BF89_RS06620	COG1183	phosphatidylcholine synthase activity
BF89_RS06635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF89_RS06670	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF89_RS06695	COG0473	3-isopropylmalate dehydrogenase activity
BF89_RS06705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF89_RS06710	COG0440	acetolactate synthase activity
BF89_RS06715	COG0028	Belongs to the TPP enzyme family
BF89_RS06720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_RS06750	COG3874	Sporulation protein YtfJ
BF89_RS06755	COG4709	membrane
BF89_RS06760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF89_RS06765	COG1301	dicarboxylic acid transport
BF89_RS06775	COG1846	Transcriptional regulator
BF89_RS06790	COG1968	undecaprenyl-diphosphatase activity
BF89_RS06795	COG0534	Mate efflux family protein
BF89_RS06815	COG3173	Aminoglycoside phosphotransferase
BF89_RS06830	COG0716	FMN binding
BF89_RS06855	COG1696	Membrane protein involved in D-alanine export
BF89_RS06865	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF89_RS06870	COG2070	2-Nitropropane dioxygenase
BF89_RS06875	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF89_RS06885	COG1335	isochorismatase
BF89_RS06895	COG1522	sequence-specific DNA binding
BF89_RS06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF89_RS06915	COG1131	(ABC) transporter
BF89_RS06925	COG1131	(ABC) transporter
BF89_RS06930	COG1725	Transcriptional regulator
BF89_RS06935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF89_RS06940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF89_RS06955	COG1780	Probably involved in ribonucleotide reductase function
BF89_RS06990	COG4873	Protein conserved in bacteria
BF89_RS07005	COG0720	synthase
BF89_RS07015	COG5002	protein histidine kinase activity
BF89_RS07025	COG2318	DinB family
BF89_RS07035	COG1846	Transcriptional regulator
BF89_RS07040	COG3852	Histidine kinase
BF89_RS07050	COG2861	carbohydrate metabolic process
BF89_RS07075	COG1349	DNA-binding transcription factor activity
BF89_RS07105	COG1840	ABC-type Fe3 transport system, periplasmic component
BF89_RS07120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF89_RS07125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_RS07130	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF89_RS07135	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS07155	COG2030	dehydratase
BF89_RS07170	COG0861	Integral membrane protein TerC family
BF89_RS07175	COG2116	formate transmembrane transporter activity
BF89_RS07185	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF89_RS07205	COG2186	Transcriptional regulator
BF89_RS07210	COG5002	protein histidine kinase activity
BF89_RS07215	COG0745	RESPONSE REGULATOR receiver
BF89_RS07225	COG3835	regulator
BF89_RS07230	COG0277	FAD linked oxidase domain protein
BF89_RS07235	COG0247	lactate metabolic process
BF89_RS07240	COG2340	Cysteine-rich secretory protein family
BF89_RS07250	COG0564	pseudouridine synthase activity
BF89_RS07260	COG2409	Drug exporters of the RND superfamily
BF89_RS07270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF89_RS07275	COG1177	transmembrane transport
BF89_RS07280	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF89_RS07285	COG3842	ATPase activity
BF89_RS07290	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS07325	COG0681	Belongs to the peptidase S26 family
BF89_RS07330	COG1686	Belongs to the peptidase S11 family
BF89_RS07340	COG2226	methyltransferase
BF89_RS07400	COG1476	TRANSCRIPTIONal
BF89_RS07410	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_RS07460	COG5634	Uncharacterized conserved protein (DUF2278)
BF89_RS07465	COG1620	l-lactate permease
BF89_RS07500	COG0512	Glutamine amidotransferase of anthranilate synthase
BF89_RS07500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF89_RS07515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_RS07520	COG5492	domain, Protein
BF89_RS07535	COG2382	esterase
BF89_RS07545	COG2153	protein acetylation
BF89_RS07590	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF89_RS07605	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF89_RS07625	COG0463	Glycosyl transferase, family 2
BF89_RS07625	COG0457	Tetratricopeptide repeat
BF89_RS07645	COG0463	Glycosyl transferase, family 2
BF89_RS07645	COG1216	Glycosyl transferase, family 2
BF89_RS07650	COG0772	Belongs to the SEDS family
BF89_RS07665	COG0564	pseudouridine synthase activity
BF89_RS07675	COG2357	RelA SpoT domain protein
BF89_RS07685	COG4116	CYTH
BF89_RS07690	COG2346	COG2346, Truncated hemoglobins
BF89_RS07695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF89_RS07705	COG1164	Oligoendopeptidase f
BF89_RS07715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_RS07720	COG4862	establishment of competence for transformation
BF89_RS07745	COG4166	transmembrane transport
BF89_RS07750	COG0534	Mate efflux family protein
BF89_RS07755	COG4608	Belongs to the ABC transporter superfamily
BF89_RS07760	COG0444	Belongs to the ABC transporter superfamily
BF89_RS07765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_RS07770	COG0601	transmembrane transport
BF89_RS07775	COG4166	transmembrane transport
BF89_RS07785	COG0180	Tryptophanyl-tRNA synthetase
BF89_RS07795	COG5504	Zn-dependent protease
BF89_RS07800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF89_RS07805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_RS07820	COG2267	carboxylic ester hydrolase activity
BF89_RS07830	COG0542	response to heat
BF89_RS07845	COG0561	phosphatase activity
BF89_RS07870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF89_RS07880	COG2996	Protein conserved in bacteria
BF89_RS07905	COG0004	ammonium transporteR
BF89_RS07910	COG0753	catalase activity
BF89_RS07915	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF89_RS07920	COG0367	asparagine synthase
BF89_RS07945	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF89_RS07990	COG1074	ATP-dependent DNA helicase activity
BF89_RS07995	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BF89_RS08005	COG0398	Pfam SNARE associated Golgi protein
BF89_RS08010	COG4903	ComK protein
BF89_RS08035	COG2224	Isocitrate lyase
BF89_RS08040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF89_RS08060	COG0697	spore germination
BF89_RS08065	COG0840	transmembrane signaling receptor activity
BF89_RS08070	COG0501	Belongs to the peptidase M48B family
BF89_RS08095	COG0745	RESPONSE REGULATOR receiver
BF89_RS08100	COG2205	protein histidine kinase activity
BF89_RS08115	COG3708	Transcriptional regulator
BF89_RS08115	COG2207	Transcriptional regulator
BF89_RS08120	COG1595	DNA-templated transcription, initiation
BF89_RS08130	COG1078	dGTPase activity
BF89_RS08135	COG1408	metallophosphoesterase
BF89_RS08180	COG3209	COG3209 Rhs family protein
BF89_RS08210	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_RS08220	COG0095	Lipoate-protein ligase
BF89_RS08225	COG1234	tRNA 3'-trailer cleavage
BF89_RS08235	COG1609	Transcriptional regulator
BF89_RS08260	COG1511	domain protein
BF89_RS08265	COG1309	transcriptional regulator
BF89_RS08300	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF89_RS08305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF89_RS08310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF89_RS08315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_RS08320	COG2329	Antibiotic biosynthesis monooxygenase
BF89_RS08325	COG3428	Bacterial PH domain
BF89_RS08330	COG3402	PFAM membrane-flanked domain
BF89_RS08375	COG3428	Bacterial PH domain
BF89_RS08385	COG3402	PFAM membrane-flanked domain
BF89_RS08395	COG1309	transcriptional regulator
BF89_RS08405	COG4473	ABC transporter
BF89_RS08410	COG1131	(ABC) transporter
BF89_RS08415	COG0537	adenosine 5'-monophosphoramidase activity
BF89_RS08420	COG4980	gas vesicle protein
BF89_RS08445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF89_RS08450	COG3973	AAA domain
BF89_RS08460	COG0477	Major facilitator Superfamily
BF89_RS08465	COG0477	Major facilitator Superfamily
BF89_RS08505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF89_RS08515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF89_RS08520	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF89_RS08540	COG2267	carboxylic ester hydrolase activity
BF89_RS08545	COG0457	Tetratricopeptide repeat
BF89_RS08550	COG0346	lactoylglutathione lyase activity
BF89_RS08555	COG0346	lactoylglutathione lyase activity
BF89_RS08560	COG2814	Major facilitator Superfamily
BF89_RS08565	COG1309	transcriptional regulator
BF89_RS08585	COG4717	serine-type aminopeptidase activity
BF89_RS08590	COG0420	3'-5' exonuclease activity
BF89_RS08650	COG2205	protein histidine kinase activity
BF89_RS08650	COG2198	Histidine kinase
BF89_RS08650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_RS08650	COG0784	Response regulator, receiver
BF89_RS08655	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF89_RS08660	COG2208	phosphoserine phosphatase activity
BF89_RS08670	COG1191	sigma factor activity
BF89_RS08695	COG3237	CsbD-like
BF89_RS08745	COG2770	Histidine kinase
BF89_RS08745	COG3437	response regulator, receiver
BF89_RS08770	COG1959	2 iron, 2 sulfur cluster binding
BF89_RS08775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF89_RS08790	COG2376	Dihydroxyacetone kinase
BF89_RS08810	COG1183	phosphatidylcholine synthase activity
BF89_RS08830	COG1309	transcriptional regulator
BF89_RS08885	COG0477	Major facilitator Superfamily
BF89_RS08925	COG0305	Participates in initiation and elongation during chromosome replication
BF89_RS08940	COG4978	Transcriptional regulator
BF89_RS08940	COG0789	Transcriptional regulator
BF89_RS08970	COG3181	Tripartite tricarboxylate transporter family receptor
BF89_RS08975	COG4565	transcriptional regulatory protein
BF89_RS08980	COG3290	protein histidine kinase activity
BF89_RS08985	COG0477	Major facilitator Superfamily
BF89_RS09015	COG4608	Belongs to the ABC transporter superfamily
BF89_RS09025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_RS09030	COG0601	transmembrane transport
BF89_RS09070	COG3938	Belongs to the proline racemase family
BF89_RS09090	COG1363	Peptidase, m42
BF89_RS09110	COG1024	Enoyl-CoA hydratase
BF89_RS09125	COG1696	Membrane protein involved in D-alanine export
BF89_RS09140	COG4196	transglutaminase domain protein
BF89_RS09145	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_RS09155	COG2244	polysaccharide biosynthetic process
BF89_RS09160	COG0653	protein targeting
BF89_RS09180	COG0659	secondary active sulfate transmembrane transporter activity
BF89_RS09195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF89_RS09210	COG0561	phosphatase activity
BF89_RS09225	COG3527	Alpha-acetolactate decarboxylase
BF89_RS09230	COG0028	Belongs to the TPP enzyme family
BF89_RS09260	COG0189	ligase activity
BF89_RS09275	COG1126	abc transporter atp-binding protein
BF89_RS09280	COG0765	amino acid transport
BF89_RS09285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_RS09300	COG1132	(ABC) transporter
BF89_RS09310	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS09320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF89_RS09325	COG0531	amino acid
BF89_RS09335	COG0753	catalase activity
BF89_RS09335	COG0693	protein deglycase activity
BF89_RS09340	COG0693	protein deglycase activity
BF89_RS09350	COG2814	Major facilitator Superfamily
BF89_RS09355	COG4533	DNA binding
BF89_RS09360	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_RS09370	COG1733	regulation of RNA biosynthetic process
BF89_RS09375	COG2814	Major facilitator Superfamily
BF89_RS09380	COG1309	transcriptional regulator
BF89_RS09385	COG2076	Multidrug Resistance protein
BF89_RS09400	COG1522	sequence-specific DNA binding
BF89_RS09405	COG0697	spore germination
BF89_RS09420	COG2259	Doxx family
BF89_RS09430	COG1263	PTS System
BF89_RS09430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_RS09440	COG1737	Transcriptional regulator
BF89_RS09450	COG0475	glutathione-regulated potassium exporter activity
BF89_RS09455	COG0531	amino acid
BF89_RS09495	COG0586	Pfam SNARE associated Golgi protein
BF89_RS09530	COG3546	catalase activity
BF89_RS09535	COG1114	Component of the transport system for branched-chain amino acids
BF89_RS09550	COG5522	Integral membrane protein (intg_mem_TP0381)
BF89_RS09560	COG1136	(ABC) transporter
BF89_RS09565	COG0577	efflux transmembrane transporter activity
BF89_RS09570	COG1388	LysM domain
BF89_RS09570	COG3584	3D domain protein
BF89_RS09590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF89_RS09595	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF89_RS09600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF89_RS09600	COG3711	transcriptional antiterminator
BF89_RS09615	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF89_RS09620	COG0604	alcohol dehydrogenase
BF89_RS09625	COG1316	TRANSCRIPTIONal
BF89_RS09635	COG0730	response to heat
BF89_RS09640	COG2210	Belongs to the sulfur carrier protein TusA family
BF89_RS09650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_RS09655	COG0425	Belongs to the sulfur carrier protein TusA family
BF89_RS09660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_RS09660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS09665	COG0425	Belongs to the sulfur carrier protein TusA family
BF89_RS09665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_RS09670	COG1937	Protein conserved in bacteria
BF89_RS09675	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF89_RS09700	COG2719	SpoVR family
BF89_RS09705	COG0778	Nitroreductase
BF89_RS09745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_RS09755	COG1609	Transcriptional regulator
BF89_RS09760	COG1263	PTS System
BF89_RS09760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_RS09765	COG1621	beta-fructofuranosidase activity
BF89_RS09770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF89_RS09780	COG1376	ErfK ybiS ycfS ynhG family protein
BF89_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS09790	COG2252	PERMEase
BF89_RS09805	COG1846	Transcriptional regulator
BF89_RS09810	COG2814	Major facilitator Superfamily
BF89_RS09815	COG2205	protein histidine kinase activity
BF89_RS09860	COG0351	phosphomethylpyrimidine kinase
BF89_RS09865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_RS09875	COG2104	thiamine diphosphate biosynthetic process
BF89_RS09880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_RS09885	COG0352	thiamine-phosphate diphosphorylase activity
BF89_RS09890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF89_RS09895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_RS09900	COG1116	anion transmembrane transporter activity
BF89_RS09905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF89_RS09930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF89_RS10050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF89_RS10060	COG0581	inorganic phosphate transmembrane transporter activity
BF89_RS10065	COG0573	inorganic phosphate transmembrane transporter activity
BF89_RS10070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF89_RS10075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF89_RS10075	COG1918	ferrous iron import across plasma membrane
BF89_RS10080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF89_RS10085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF89_RS10100	COG0531	amino acid
BF89_RS10105	COG0697	spore germination
BF89_RS10110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_RS10125	COG4990	cell redox homeostasis
BF89_RS10130	COG0833	amino acid
BF89_RS10135	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF89_RS10140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF89_RS10155	COG0475	glutathione-regulated potassium exporter activity
BF89_RS10155	COG0569	domain protein
BF89_RS10180	COG2252	PERMEase
BF89_RS10185	COG1113	amino acid transport
BF89_RS10200	COG1114	Component of the transport system for branched-chain amino acids
BF89_RS10205	COG3104	oligopeptide transport
BF89_RS10220	COG1476	TRANSCRIPTIONal
BF89_RS10225	COG3584	3D domain protein
BF89_RS10225	COG1388	LysM domain
BF89_RS10230	COG0840	transmembrane signaling receptor activity
BF89_RS10235	COG1968	undecaprenyl-diphosphatase activity
BF89_RS10260	COG3568	Endonuclease Exonuclease Phosphatase
BF89_RS10275	COG1063	alcohol dehydrogenase
BF89_RS10300	COG1879	ABC-type sugar transport system periplasmic component
BF89_RS10305	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF89_RS10320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF89_RS10325	COG1609	Transcriptional regulator
BF89_RS10330	COG0477	Major facilitator Superfamily
BF89_RS10335	COG0477	Major facilitator Superfamily
BF89_RS10340	COG1846	Transcriptional regulator
BF89_RS10345	COG2271	Major facilitator Superfamily
BF89_RS10355	COG4608	Belongs to the ABC transporter superfamily
BF89_RS10360	COG0601	transmembrane transport
BF89_RS10370	COG0747	negative chemotaxis
BF89_RS10385	COG0659	secondary active sulfate transmembrane transporter activity
BF89_RS10400	COG5002	protein histidine kinase activity
BF89_RS10405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF89_RS10410	COG2378	regulation of single-species biofilm formation
BF89_RS10435	COG0833	amino acid
BF89_RS10440	COG0765	amino acid transport
BF89_RS10445	COG0765	amino acid transport
BF89_RS10450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_RS10455	COG1126	abc transporter atp-binding protein
BF89_RS10460	COG1115	amino acid carrier protein
BF89_RS10465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF89_RS10475	COG0697	spore germination
BF89_RS10490	COG0366	Alpha amylase catalytic
BF89_RS10495	COG1263	PTS System
BF89_RS10495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_RS10500	COG2188	Transcriptional regulator
BF89_RS10505	COG0531	amino acid
BF89_RS10525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_RS10530	COG0714	Associated with various cellular activities
BF89_RS10535	COG4548	von Willebrand factor, type A
BF89_RS10545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF89_RS10550	COG0156	8-amino-7-oxononanoate synthase activity
BF89_RS10555	COG2226	methyltransferase
BF89_RS10565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS10570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS10575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS10580	COG3104	oligopeptide transport
BF89_RS10595	COG1620	l-lactate permease
BF89_RS10600	COG1027	Aspartate ammonia-lyase
BF89_RS10605	COG1253	flavin adenine dinucleotide binding
BF89_RS10610	COG0346	lactoylglutathione lyase activity
BF89_RS10615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS10620	COG1316	TRANSCRIPTIONal
BF89_RS10625	COG2720	vancomycin resistance protein
BF89_RS10645	COG3227	Zinc metalloprotease (Elastase)
BF89_RS10655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF89_RS10660	COG2217	Heavy metal translocating P-type atpase
BF89_RS10665	COG0640	Transcriptional regulator
BF89_RS10670	COG0531	amino acid
BF89_RS10685	COG2427	Protein of unknown function (DUF1641)
BF89_RS10690	COG3383	formate dehydrogenase (NAD+) activity
BF89_RS10695	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF89_RS10700	COG0456	acetyltransferase
BF89_RS10700	COG0454	-acetyltransferase
BF89_RS10710	COG0745	RESPONSE REGULATOR receiver
BF89_RS10715	COG5002	protein histidine kinase activity
BF89_RS10725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS10740	COG0281	malic enzyme
BF89_RS10745	COG3493	citrate carrier protein
BF89_RS10750	COG4565	transcriptional regulatory protein
BF89_RS10755	COG3290	protein histidine kinase activity
BF89_RS10765	COG4990	cell redox homeostasis
BF89_RS10775	COG5002	protein histidine kinase activity
BF89_RS10780	COG0745	RESPONSE REGULATOR receiver
BF89_RS10785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF89_RS10795	COG0395	ABC-type sugar transport system, permease component
BF89_RS10800	COG1175	transmembrane transport
BF89_RS10805	COG3842	ATPase activity
BF89_RS10810	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF89_RS10830	COG2851	Citrate transporter
BF89_RS10835	COG4565	transcriptional regulatory protein
BF89_RS10840	COG3290	protein histidine kinase activity
BF89_RS10850	COG2268	Band 7 protein
BF89_RS10855	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF89_RS10865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF89_RS10890	COG2766	serine protein kinase
BF89_RS10905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF89_RS10915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF89_RS10925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF89_RS10930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF89_RS11045	COG0735	belongs to the Fur family
BF89_RS11050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF89_RS11070	COG4555	ABC transporter
BF89_RS11080	COG0069	glutamate synthase activity
BF89_RS11080	COG0070	glutamate synthase
BF89_RS11080	COG0067	glutamate synthase
BF89_RS11085	COG4129	membrane
BF89_RS11090	COG1132	(ABC) transporter
BF89_RS11115	COG1194	a g-specific adenine glycosylase
BF89_RS11120	COG1988	membrane-bound metal-dependent
BF89_RS11150	COG1090	epimerase
BF89_RS11155	COG1228	amidohydrolase
BF89_RS11175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF89_RS11195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF89_RS11195	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF89_RS11210	COG0463	Glycosyl transferase, family 2
BF89_RS11225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_RS11230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_RS11230	COG1263	PTS System
BF89_RS11265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF89_RS11270	COG0833	amino acid
BF89_RS11280	COG3829	transcription factor binding
BF89_RS11290	COG0101	tRNA pseudouridine synthase activity
BF89_RS11410	COG0582	viral genome integration into host DNA
BF89_RS11415	COG0582	viral genome integration into host DNA
BF89_RS11510	COG1484	DNA-dependent DNA replication
BF89_RS11545	COG1396	sequence-specific DNA binding
BF89_RS11560	COG1396	sequence-specific DNA binding
BF89_RS11565	COG0582	viral genome integration into host DNA
BF89_RS11570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF89_RS11575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF89_RS11600	COG0535	radical SAM domain protein
BF89_RS11610	COG0387	Pfam Sodium calcium exchanger
BF89_RS11615	COG3871	stress protein (general stress protein 26)
BF89_RS11630	COG0586	Pfam SNARE associated Golgi protein
BF89_RS11650	COG0697	spore germination
BF89_RS11655	COG2217	Heavy metal translocating P-type atpase
BF89_RS11660	COG1295	ribonuclease BN
BF89_RS11670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF89_RS11685	COG3853	Toxic anion resistance protein (TelA)
BF89_RS11695	COG0861	Integral membrane protein TerC family
BF89_RS11700	COG2310	stress, protein
BF89_RS11705	COG2310	stress, protein
BF89_RS11710	COG2310	stress, protein
BF89_RS11725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF89_RS11740	COG2270	Major facilitator Superfamily
BF89_RS11785	COG0488	(ABC) transporter
BF89_RS11790	COG1116	anion transmembrane transporter activity
BF89_RS11800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_RS11815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF89_RS11845	COG1263	PTS System
BF89_RS11845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_RS11845	COG2190	(PTS) system
BF89_RS11850	COG0366	Alpha amylase catalytic
BF89_RS11855	COG0840	transmembrane signaling receptor activity
BF89_RS11860	COG0840	transmembrane signaling receptor activity
BF89_RS11870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_RS11875	COG0765	amino acid transport
BF89_RS11885	COG0723	plastoquinol--plastocyanin reductase activity
BF89_RS11885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_RS11890	COG2814	Major facilitator Superfamily
BF89_RS11895	COG3541	Predicted nucleotidyltransferase
BF89_RS11915	COG5002	protein histidine kinase activity
BF89_RS11950	COG0166	Belongs to the GPI family
BF89_RS11970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS11975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS11980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS12000	COG0450	alkyl hydroperoxide reductase
BF89_RS12015	COG1473	amidohydrolase
BF89_RS12020	COG1757	Na H antiporter
BF89_RS12045	COG4807	Protein conserved in bacteria
BF89_RS12055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF89_RS12060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF89_RS12065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS12080	COG2309	aminopeptidase activity
BF89_RS12085	COG2076	Multidrug Resistance protein
BF89_RS12090	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS12100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF89_RS12105	COG0546	phosphoglycolate phosphatase activity
BF89_RS12110	COG1597	lipid kinase activity
BF89_RS12135	COG1846	Transcriptional regulator
BF89_RS12155	COG1464	Belongs to the NlpA lipoprotein family
BF89_RS12160	COG2011	ABC-type metal ion transport system permease component
BF89_RS12165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF89_RS12170	COG1335	isochorismatase
BF89_RS12190	COG4851	CamS sex pheromone cAM373 precursor
BF89_RS12200	COG0210	DNA helicase
BF89_RS12225	COG0151	Belongs to the GarS family
BF89_RS12235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF89_RS12245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF89_RS12260	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF89_RS12270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF89_RS12275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF89_RS12280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF89_RS12305	COG0745	RESPONSE REGULATOR receiver
BF89_RS12310	COG2205	protein histidine kinase activity
BF89_RS12325	COG1968	undecaprenyl-diphosphatase activity
BF89_RS12345	COG5002	protein histidine kinase activity
BF89_RS12355	COG2252	PERMEase
BF89_RS12375	COG1266	CAAX protease self-immunity
BF89_RS12390	COG0488	(ABC) transporter
BF89_RS12400	COG0456	acetyltransferase
BF89_RS12405	COG1214	PFAM Peptidase M22, glycoprotease
BF89_RS12410	COG0802	atpase or kinase
BF89_RS12505	COG2183	response to ionizing radiation
BF89_RS12510	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF89_RS12515	COG0864	Transcriptional regulator
BF89_RS12520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF89_RS12525	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF89_RS12535	COG0705	Rhomboid family
BF89_RS12535	COG0457	Tetratricopeptide repeat
BF89_RS12540	COG4294	response to UV
BF89_RS12550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF89_RS12565	COG2814	Major facilitator Superfamily
BF89_RS12575	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF89_RS12580	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF89_RS12610	COG4608	Belongs to the ABC transporter superfamily
BF89_RS12615	COG0444	Belongs to the ABC transporter superfamily
BF89_RS12620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_RS12625	COG0601	transmembrane transport
BF89_RS12630	COG0747	negative chemotaxis
BF89_RS12645	COG0488	(ABC) transporter
BF89_RS12670	COG5298	Protein conserved in bacteria
BF89_RS12675	COG0084	hydrolase, TatD family'
BF89_RS12690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS12700	COG1609	Transcriptional regulator
BF89_RS12710	COG0204	Acyl-transferase
BF89_RS12720	COG0697	spore germination
BF89_RS12725	COG0583	DNA-binding transcription factor activity
BF89_RS12740	COG1910	domain protein
BF89_RS12745	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF89_RS12750	COG4149	molybdate abc transporter
BF89_RS12770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_RS12775	COG0656	L-ascorbic acid biosynthetic process
BF89_RS12780	COG4166	transmembrane transport
BF89_RS12785	COG4166	transmembrane transport
BF89_RS12800	COG2207	Transcriptional regulator
BF89_RS12810	COG4166	transmembrane transport
BF89_RS12815	COG4608	Belongs to the ABC transporter superfamily
BF89_RS12820	COG0444	Belongs to the ABC transporter superfamily
BF89_RS12825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_RS12830	COG0601	transmembrane transport
BF89_RS12845	COG2814	Major facilitator Superfamily
BF89_RS12855	COG2271	Major facilitator Superfamily
BF89_RS12870	COG0604	alcohol dehydrogenase
BF89_RS12875	COG1464	Belongs to the NlpA lipoprotein family
BF89_RS12880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF89_RS12885	COG2011	ABC-type metal ion transport system permease component
BF89_RS12890	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS12920	COG0823	Involved in the tonB-independent uptake of proteins
BF89_RS12920	COG1506	peptidase
BF89_RS12920	COG4946	Tricorn protease homolog
BF89_RS12925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF89_RS12945	COG0596	Alpha beta hydrolase
BF89_RS12950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF89_RS12965	COG4856	YbbR-like protein
BF89_RS12970	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF89_RS13055	COG0726	polysaccharide deacetylase
BF89_RS13060	COG2194	sulfuric ester hydrolase activity
BF89_RS13070	COG0489	protein tyrosine kinase activity
BF89_RS13075	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_RS13100	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF89_RS13135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF89_RS13145	COG0024	Methionine aminopeptidase
BF89_RS13155	COG0201	protein transport
BF89_RS13215	COG0255	Belongs to the universal ribosomal protein uL29 family
BF89_RS13285	COG1358	cellular component organization or biogenesis
BF89_RS13290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF89_RS13300	COG2813	Specifically methylates the guanine in position
BF89_RS13320	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BF89_RS13325	COG0250	Participates in transcription elongation, termination and antitermination
BF89_RS13330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF89_RS13345	COG3688	RNA-binding protein containing a PIN domain
BF89_RS13350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF89_RS13365	COG1045	serine acetyltransferase
BF89_RS13385	COG4956	integral membrane protein (PIN domain superfamily)
BF89_RS13395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF89_RS13400	COG0542	response to heat
BF89_RS13410	COG3880	PFAM UvrB UvrC protein
BF89_RS13440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF89_RS13445	COG1396	sequence-specific DNA binding
BF89_RS13450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF89_RS13455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF89_RS13460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF89_RS13465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF89_RS13470	COG0512	Glutamine amidotransferase of anthranilate synthase
BF89_RS13475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF89_RS13480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF89_RS13495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF89_RS13500	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF89_RS13505	COG0037	tRNA processing
BF89_RS13510	COG2208	phosphoserine phosphatase activity
BF89_RS13525	COG1098	S1 RNA binding domain
BF89_RS13545	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF89_RS13550	COG3956	TIGRFAM MazG family protein
BF89_RS13555	COG2244	polysaccharide biosynthetic process
BF89_RS13560	COG2002	toxin-antitoxin pair type II binding
BF89_RS13565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF89_RS13595	COG0251	oxidation-reduction process
BF89_RS13600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF89_RS13615	COG4466	Protein conserved in bacteria
BF89_RS13630	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF89_RS13635	COG0084	hydrolase, TatD family'
BF89_RS13640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_RS13640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_RS13645	COG2002	toxin-antitoxin pair type II binding
BF89_RS13650	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF89_RS13660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF89_RS13670	COG1774	PSP1 C-terminal conserved region
BF89_RS13675	COG0470	DNA polymerase III
BF89_RS13685	COG1982	Orn Lys Arg decarboxylase major
BF89_RS13740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF89_RS13745	COG0590	tRNA wobble adenosine to inosine editing
BF89_RS13755	COG1335	isochorismatase
BF89_RS13760	COG1428	Deoxynucleoside kinase
BF89_RS13765	COG1428	Deoxynucleoside kinase
BF89_RS13795	COG1686	Belongs to the peptidase S11 family
BF89_RS13800	COG0517	IMP dehydrogenase activity
BF89_RS13800	COG0516	GMP reductase activity
BF89_RS13835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF89_RS13840	COG0187	DNA topoisomerase II activity
BF89_RS13850	COG2501	S4 domain
BF89_RS13855	COG0592	DNA-directed DNA polymerase activity
BF89_RS13865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BF89_RS13875	COG0706	membrane insertase activity
BF89_RS13880	COG1847	R3H domain protein
BF89_RS13905	COG1192	Involved in chromosome partitioning
BF89_RS13910	COG1475	DNA binding
BF89_RS13920	COG0668	transmembrane transport
BF89_RS13925	COG4481	Protein conserved in bacteria
BF89_RS13930	COG0012	GTP binding
BF89_RS13940	COG0629	single-stranded DNA binding
BF89_RS13950	COG4241	membrane
BF89_RS13955	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF89_RS13965	COG0305	Participates in initiation and elongation during chromosome replication
BF89_RS13995	COG0745	RESPONSE REGULATOR receiver
BF89_RS14000	COG5002	protein histidine kinase activity
BF89_RS14005	COG4863	YycH protein
BF89_RS14010	COG4853	Protein conserved in bacteria
BF89_RS14015	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF89_RS14020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF89_RS14040	COG1164	Oligoendopeptidase f
BF89_RS14065	COG1272	protein, Hemolysin III
BF89_RS14070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF89_RS14090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF89_RS14095	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF89_RS14100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF89_RS14105	COG2814	Major facilitator Superfamily
BF89_RS14110	COG3275	phosphorelay sensor kinase activity
BF89_RS14115	COG3279	Response regulator of the LytR AlgR family
BF89_RS14130	COG0628	permease
BF89_RS14135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF89_RS14135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF89_RS14140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF89_RS14145	COG1309	transcriptional regulator
BF89_RS14150	COG0463	Glycosyl transferase, family 2
BF89_RS14175	COG0488	(ABC) transporter
BF89_RS14190	COG1607	acyl-coa hydrolase
BF89_RS14225	COG0477	Major facilitator Superfamily
BF89_RS14230	COG3279	Response regulator of the LytR AlgR family
BF89_RS14235	COG1966	Carbon starvation protein
BF89_RS14240	COG2879	small protein
BF89_RS14245	COG3706	GGDEF domain
BF89_RS14250	COG0351	phosphomethylpyrimidine kinase
BF89_RS14260	COG2197	response regulator
BF89_RS14270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF89_RS14275	COG1011	Hydrolase
BF89_RS14285	COG2873	o-acetylhomoserine
BF89_RS14295	COG0460	homoserine dehydrogenase
BF89_RS14305	COG1609	Transcriptional regulator
BF89_RS14310	COG2755	lipolytic protein G-D-S-L family
BF89_RS14315	COG1131	(ABC) transporter
BF89_RS14320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF89_RS14330	COG2814	Major facilitator Superfamily
BF89_RS14335	COG0561	phosphatase activity
BF89_RS14340	COG2233	PERMEase
BF89_RS14345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF89_RS14355	COG2363	Small membrane protein
BF89_RS14365	COG3773	Cell wall hydrolase
BF89_RS14380	COG0280	phosphate acetyltransferase
BF89_RS14385	COG0095	Lipoate-protein ligase
BF89_RS14405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS14410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS14415	COG1120	ATPase activity
BF89_RS14420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS14425	COG1078	dGTPase activity
BF89_RS14435	COG1994	Peptidase M50
BF89_RS14445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF89_RS14450	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_RS14455	COG0789	Transcriptional regulator
BF89_RS14460	COG2814	Major facilitator Superfamily
BF89_RS14470	COG0010	Belongs to the arginase family
BF89_RS14490	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF89_RS14495	COG4506	Protein conserved in bacteria
BF89_RS14500	COG0018	arginyl-trna synthetase
BF89_RS14505	COG1595	DNA-templated transcription, initiation
BF89_RS14525	COG2234	aminopeptidase activity
BF89_RS14540	COG0024	Methionine aminopeptidase
BF89_RS14545	COG1131	(ABC) transporter
BF89_RS14550	COG0842	Transport permease protein
BF89_RS14555	COG4585	Histidine kinase
BF89_RS14560	COG2197	response regulator
BF89_RS14575	COG3300	MHYT domain
BF89_RS14575	COG5001	Diguanylate cyclase
BF89_RS14585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF89_RS14590	COG0247	lactate metabolic process
BF89_RS14590	COG2181	nitrate reductase activity
BF89_RS14595	COG0183	Belongs to the thiolase family
BF89_RS14600	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF89_RS14605	COG1960	acyl-CoA dehydrogenase activity
BF89_RS14610	COG1960	acyl-CoA dehydrogenase activity
BF89_RS14620	COG3343	RNA polymerase activity
BF89_RS14630	COG4821	SIS domain
BF89_RS14650	COG1494	fructose-1,6-bisphosphatase
BF89_RS14655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF89_RS14675	COG2890	protein-(glutamine-N5) methyltransferase activity
BF89_RS14690	COG0009	L-threonylcarbamoyladenylate synthase
BF89_RS14705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF89_RS14710	COG2259	Doxx family
BF89_RS14715	COG2190	(PTS) system
BF89_RS14725	COG0698	ribose 5-phosphate isomerase
BF89_RS14760	COG0356	it plays a direct role in the translocation of protons across the membrane
BF89_RS14810	COG3300	MHYT domain
BF89_RS14810	COG5001	Diguanylate cyclase
BF89_RS14825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF89_RS14830	COG0649	NAD binding
BF89_RS14845	COG0839	Belongs to the complex I subunit 6 family
BF89_RS14855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF89_RS14860	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF89_RS14865	COG1007	ATP synthesis coupled electron transport
BF89_RS14870	COG4836	Membrane
BF89_RS14885	COG2385	sporulation resulting in formation of a cellular spore
BF89_RS14890	COG4555	ABC transporter
BF89_RS14895	COG3279	Response regulator of the LytR AlgR family
BF89_RS14910	COG0739	heme binding
BF89_RS14925	COG1609	Transcriptional regulator
BF89_RS14970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF89_RS14975	COG1682	transport, permease protein
BF89_RS14980	COG1134	teichoic acid transport
BF89_RS14985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF89_RS15000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF89_RS15005	COG0745	RESPONSE REGULATOR receiver
BF89_RS15010	COG5002	protein histidine kinase activity
BF89_RS15045	COG1136	(ABC) transporter
BF89_RS15050	COG0577	efflux transmembrane transporter activity
BF89_RS15090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF89_RS15095	COG4715	Zinc finger, swim domain protein
BF89_RS15120	COG3584	3D domain protein
BF89_RS15120	COG1388	LysM domain
BF89_RS15125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF89_RS15135	COG1215	transferase activity, transferring glycosyl groups
BF89_RS15145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS15160	COG1368	sulfuric ester hydrolase activity
BF89_RS15170	COG2389	metal-binding protein
BF89_RS15190	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF89_RS15195	COG1294	oxidase, subunit
BF89_RS15200	COG1271	oxidase subunit
BF89_RS15215	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF89_RS15220	COG0583	DNA-binding transcription factor activity
BF89_RS15225	COG1511	domain protein
BF89_RS15230	COG0346	lactoylglutathione lyase activity
BF89_RS15240	COG1301	dicarboxylic acid transport
BF89_RS15245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF89_RS15255	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF89_RS15260	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF89_RS15265	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF89_RS15275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF89_RS15280	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF89_RS15285	COG1486	melibiose metabolic process
BF89_RS15290	COG3394	polysaccharide catabolic process
BF89_RS15305	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF89_RS15305	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF89_RS15315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF89_RS15320	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF89_RS15325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF89_RS15330	COG1316	TRANSCRIPTIONal
BF89_RS15335	COG1739	Uncharacterized protein family UPF0029
BF89_RS15340	COG1307	EDD domain protein, DegV family
BF89_RS15350	COG1733	regulation of RNA biosynthetic process
BF89_RS15355	COG1388	LysM domain
BF89_RS15355	COG0791	NLP P60 protein
BF89_RS15365	COG1040	competence protein
BF89_RS15370	COG1278	Cold shock
BF89_RS15375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF89_RS15380	COG0653	protein targeting
BF89_RS15385	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF89_RS15400	COG2884	Cell division ATP-binding protein ftsE
BF89_RS15405	COG2177	Part of the ABC transporter FtsEX involved in
BF89_RS15410	COG3409	Peptidoglycan-binding domain 1 protein
BF89_RS15410	COG0793	Belongs to the peptidase S41A family
BF89_RS15415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF89_RS15420	COG1132	(ABC) transporter
BF89_RS15430	COG0488	(ABC) transporter
BF89_RS15435	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF89_RS15445	COG0583	DNA-binding transcription factor activity
BF89_RS15450	COG2855	membrane
BF89_RS15475	COG0789	Transcriptional regulator
BF89_RS15495	COG0556	nucleotide-excision repair
BF89_RS15500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF89_RS15510	COG1950	PFAM Membrane protein of
BF89_RS15530	COG0110	maltose O-acetyltransferase activity
BF89_RS15535	COG0457	Tetratricopeptide repeat
BF89_RS15540	COG0492	ferredoxin-NADP+ reductase activity
BF89_RS15550	COG1051	belongs to the nudix hydrolase family
BF89_RS15560	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF89_RS15570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF89_RS15575	COG0740	serine-type endopeptidase activity
BF89_RS15580	COG2323	membrane
BF89_RS15595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_RS15620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF89_RS15635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF89_RS15645	COG0149	triose-phosphate isomerase activity
BF89_RS15660	COG4974	Belongs to the 'phage' integrase family
BF89_RS15685	COG4695	Portal protein
BF89_RS15785	COG1346	cytolysis
BF89_RS15790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF89_RS15795	COG1647	Serine aminopeptidase, S33
BF89_RS15800	COG0557	exoribonuclease II activity
BF89_RS15850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS15865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF89_RS15870	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF89_RS15880	COG3290	protein histidine kinase activity
BF89_RS15880	COG0840	transmembrane signaling receptor activity
BF89_RS15890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF89_RS15895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF89_RS15900	COG1252	NADH dehydrogenase
BF89_RS15910	COG1733	regulation of RNA biosynthetic process
BF89_RS15915	COG2814	Major facilitator Superfamily
BF89_RS15920	COG0656	L-ascorbic acid biosynthetic process
BF89_RS15935	COG2910	NAD(P)H-binding
BF89_RS15940	COG1115	amino acid carrier protein
BF89_RS15945	COG1115	amino acid carrier protein
BF89_RS15950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS15955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS15965	COG2311	Membrane
BF89_RS15980	COG1611	Belongs to the LOG family
BF89_RS15995	COG0783	Belongs to the Dps family
BF89_RS16000	COG1115	amino acid carrier protein
BF89_RS16010	COG0490	domain, Protein
BF89_RS16015	COG0475	glutathione-regulated potassium exporter activity
BF89_RS16030	COG1741	Belongs to the pirin family
BF89_RS16035	COG3227	Zinc metalloprotease (Elastase)
BF89_RS16040	COG2151	metal-sulfur cluster biosynthetic enzyme
BF89_RS16065	COG5002	protein histidine kinase activity
BF89_RS16070	COG0745	RESPONSE REGULATOR receiver
BF89_RS16075	COG1376	ErfK ybiS ycfS ynhG family protein
BF89_RS16085	COG0586	Pfam SNARE associated Golgi protein
BF89_RS16120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS16130	COG0706	membrane insertase activity
BF89_RS16140	COG0531	amino acid
BF89_RS16145	COG2814	Major facilitator Superfamily
BF89_RS16165	COG0840	transmembrane signaling receptor activity
BF89_RS16170	COG0011	TIGRFAM Protein of
BF89_RS16185	COG1686	Belongs to the peptidase S11 family
BF89_RS16195	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF89_RS16195	COG1024	Enoyl-CoA hydratase
BF89_RS16200	COG0183	Belongs to the thiolase family
BF89_RS16210	COG1960	acyl-CoA dehydrogenase activity
BF89_RS16215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS16220	COG1309	transcriptional regulator
BF89_RS16245	COG0039	L-malate dehydrogenase activity
BF89_RS16295	COG1393	Belongs to the ArsC family
BF89_RS16305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF89_RS16310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_RS16325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF89_RS16330	COG2011	ABC-type metal ion transport system permease component
BF89_RS16335	COG1464	Belongs to the NlpA lipoprotein family
BF89_RS16340	COG1464	Belongs to the NlpA lipoprotein family
BF89_RS16345	COG0396	ATPase activity
BF89_RS16350	COG0719	Fe-S assembly protein
BF89_RS16355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF89_RS16360	COG0822	iron-sulfur transferase activity
BF89_RS16365	COG0719	Fe-S assembly protein
BF89_RS16380	COG1695	Transcriptional regulator
BF89_RS16390	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS16395	COG3377	Domain of unknown function (DUF1805)
BF89_RS16405	COG0739	heme binding
BF89_RS16430	COG4377	Putative membrane peptidase family (DUF2324)
BF89_RS16435	COG0789	Transcriptional regulator
BF89_RS16445	COG4470	Protein conserved in bacteria
BF89_RS16465	COG1494	fructose-1,6-bisphosphatase
BF89_RS16470	COG2445	Protein of unknown function DUF86
BF89_RS16480	COG0647	UMP catabolic process
BF89_RS16485	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_RS16500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF89_RS16505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF89_RS16515	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF89_RS16520	COG4837	Protein of unknown function (DUF1462)
BF89_RS16560	COG2824	Alkylphosphonate utilization operon protein PhnA
BF89_RS16565	COG0390	transport system, permease component
BF89_RS16570	COG2274	protein secretion by the type I secretion system
BF89_RS16580	COG1252	NADH dehydrogenase
BF89_RS16595	COG0316	Belongs to the HesB IscA family
BF89_RS16615	COG1683	Conserved Protein
BF89_RS16630	COG3708	Transcriptional regulator
BF89_RS16645	COG1252	NADH dehydrogenase
BF89_RS16660	COG3584	3D domain protein
BF89_RS16675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF89_RS16680	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF89_RS16690	COG1268	BioY protein
BF89_RS16700	COG2050	protein possibly involved in aromatic compounds catabolism
BF89_RS16720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF89_RS16725	COG5018	Exonuclease
BF89_RS16745	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF89_RS16755	COG2267	carboxylic ester hydrolase activity
BF89_RS16760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF89_RS16765	COG1522	sequence-specific DNA binding
BF89_RS16770	COG0436	Aminotransferase
BF89_RS16775	COG1098	S1 RNA binding domain
BF89_RS16780	COG2155	Conserved Protein
BF89_RS16790	COG0166	Belongs to the GPI family
BF89_RS16800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF89_RS16805	COG1285	pathogenesis
BF89_RS16840	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF89_RS16950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF89_RS16955	COG0297	glycogen (starch) synthase activity
BF89_RS16960	COG0058	SHG alpha-glucan phosphorylase activity
BF89_RS16985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF89_RS16990	COG1575	Belongs to the MenA family. Type 1 subfamily
BF89_RS16995	COG1169	isochorismate synthase
BF89_RS17000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF89_RS17005	COG0596	Alpha beta hydrolase
BF89_RS17010	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF89_RS17020	COG4948	Mandelate Racemase Muconate Lactonizing
BF89_RS17050	COG3964	amidohydrolase
BF89_RS17070	COG2188	Transcriptional regulator
BF89_RS17090	COG1136	(ABC) transporter
BF89_RS17095	COG0577	efflux transmembrane transporter activity
BF89_RS17100	COG0577	efflux transmembrane transporter activity
BF89_RS17105	COG2205	protein histidine kinase activity
BF89_RS17110	COG0745	RESPONSE REGULATOR receiver
BF89_RS17120	COG1136	(ABC) transporter
BF89_RS17125	COG0577	efflux transmembrane transporter activity
BF89_RS17135	COG0586	Pfam SNARE associated Golgi protein
BF89_RS17170	COG1597	lipid kinase activity
BF89_RS17175	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF89_RS17200	COG0745	RESPONSE REGULATOR receiver
BF89_RS17205	COG5002	protein histidine kinase activity
BF89_RS17240	COG1842	Phage shock protein A
BF89_RS17265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS17285	COG1294	oxidase, subunit
BF89_RS17290	COG1271	oxidase subunit
BF89_RS17295	COG0288	reversible hydration of carbon dioxide
BF89_RS17325	COG0494	nUDIX hydrolase
BF89_RS17350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_RS17355	COG1116	anion transmembrane transporter activity
BF89_RS17360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF89_RS17380	COG2267	carboxylic ester hydrolase activity
BF89_RS17385	COG4191	Histidine kinase
BF89_RS17390	COG5002	protein histidine kinase activity
BF89_RS17395	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF89_RS17450	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF89_RS17460	COG0438	transferase activity, transferring glycosyl groups
BF89_RS17465	COG0671	phosphoesterase, PA-phosphatase related
BF89_RS17470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF89_RS17475	COG2267	carboxylic ester hydrolase activity
BF89_RS17495	COG1794	racemase activity, acting on amino acids and derivatives
BF89_RS17505	COG1131	(ABC) transporter
BF89_RS17510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF89_RS17515	COG1242	4 iron, 4 sulfur cluster binding
BF89_RS17535	COG1136	(ABC) transporter
BF89_RS17545	COG0582	viral genome integration into host DNA
BF89_RS17550	COG0490	domain, Protein
BF89_RS17555	COG0475	glutathione-regulated potassium exporter activity
BF89_RS17560	COG2814	Major facilitator Superfamily
BF89_RS17605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF89_RS17615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_RS17635	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF89_RS17640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_RS17650	COG0303	'Molybdopterin
BF89_RS17655	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF89_RS17660	COG0314	molybdopterin synthase activity
BF89_RS17675	COG4975	Glucose uptake
BF89_RS17685	COG1329	Transcriptional regulator
BF89_RS17705	COG3832	glyoxalase III activity
BF89_RS17715	COG2814	Major facilitator Superfamily
BF89_RS17720	COG2081	HI0933 family
BF89_RS17725	COG2244	polysaccharide biosynthetic process
BF89_RS17730	COG1187	pseudouridine synthase activity
BF89_RS17735	COG1349	DNA-binding transcription factor activity
BF89_RS17740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF89_RS17755	COG1523	belongs to the glycosyl hydrolase 13 family
BF89_RS17760	COG0510	thiamine kinase activity
BF89_RS17775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS17785	COG1363	Peptidase, m42
BF89_RS17790	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF89_RS17795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_RS17800	COG4848	Belongs to the UPF0354 family
BF89_RS17805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF89_RS17815	COG1674	ftsk spoiiie
BF89_RS17830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS17850	COG2309	aminopeptidase activity
BF89_RS17860	COG3118	belongs to the thioredoxin family
BF89_RS17865	COG4851	CamS sex pheromone cAM373 precursor
BF89_RS17875	COG1609	Transcriptional regulator
BF89_RS17910	COG0666	response to abiotic stimulus
BF89_RS17920	COG0745	RESPONSE REGULATOR receiver
BF89_RS17930	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF89_RS17935	COG0517	IMP dehydrogenase activity
BF89_RS17940	COG0454	-acetyltransferase
BF89_RS17945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF89_RS17955	COG1595	DNA-templated transcription, initiation
BF89_RS17985	COG0626	cystathionine gamma-synthase activity
BF89_RS17990	COG1956	GAF domain-containing protein
BF89_RS18000	COG0697	spore germination
BF89_RS18005	COG0583	DNA-binding transcription factor activity
BF89_RS18015	COG1104	cysteine desulfurase activity
BF89_RS18030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF89_RS18040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF89_RS18055	COG3874	Sporulation protein YtfJ
BF89_RS18060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF89_RS18065	COG0827	DNA restriction-modification system
BF89_RS18070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF89_RS18090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS18130	COG0589	response to stress
BF89_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS18150	COG1476	TRANSCRIPTIONal
BF89_RS18160	COG0662	Cupin 2, conserved barrel domain protein
BF89_RS18165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS18200	COG0006	proline dipeptidase activity
BF89_RS18215	COG4109	DRTGG domain
BF89_RS18235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF89_RS18250	COG0587	DNA-directed DNA polymerase activity
BF89_RS18255	COG0281	malic enzyme
BF89_RS18260	COG1725	Transcriptional regulator
BF89_RS18285	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF89_RS18290	COG0628	permease
BF89_RS18305	COG0372	Belongs to the citrate synthase family
BF89_RS18310	COG0538	isocitrate dehydrogenase activity
BF89_RS18330	COG0745	RESPONSE REGULATOR receiver
BF89_RS18335	COG5002	protein histidine kinase activity
BF89_RS18340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF89_RS18340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF89_RS18350	COG1971	Probably functions as a manganese efflux pump
BF89_RS18355	COG0237	dephospho-CoA kinase activity
BF89_RS18360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF89_RS18365	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF89_RS18375	COG3611	Membrane attachment protein
BF89_RS18380	COG1484	DNA-dependent DNA replication
BF89_RS18390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF89_RS18415	COG1363	Peptidase, m42
BF89_RS18420	COG1309	transcriptional regulator
BF89_RS18425	COG1566	PFAM secretion protein HlyD family protein
BF89_RS18430	COG2814	Major facilitator Superfamily
BF89_RS18455	COG1418	mRNA catabolic process
BF89_RS18465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF89_RS18510	COG1286	toxin biosynthetic process
BF89_RS18515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF89_RS18515	COG1796	DNA polymerase
BF89_RS18530	COG1187	pseudouridine synthase activity
BF89_RS18535	COG1114	Component of the transport system for branched-chain amino acids
BF89_RS18540	COG5386	Cell surface protein
BF89_RS18550	COG5386	Cell surface protein
BF89_RS18565	COG1120	ATPase activity
BF89_RS18570	COG4509	Sortase family
BF89_RS18585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF89_RS18590	COG4895	conserved protein (DUF2196)
BF89_RS18600	COG0745	RESPONSE REGULATOR receiver
BF89_RS18605	COG2205	protein histidine kinase activity
BF89_RS18610	COG1131	(ABC) transporter
BF89_RS18640	COG2318	DinB family
BF89_RS18660	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_RS18665	COG1309	transcriptional regulator
BF89_RS18670	COG1024	Enoyl-CoA hydratase
BF89_RS18675	COG2086	electron transfer activity
BF89_RS18680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF89_RS18685	COG3118	belongs to the thioredoxin family
BF89_RS18695	COG1719	4-vinyl reductase, 4VR
BF89_RS18700	COG2009	succinate dehydrogenase
BF89_RS18705	COG1053	succinate dehydrogenase
BF89_RS18710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF89_RS18715	COG0824	Thioesterase
BF89_RS18720	COG1876	peptidase activity
BF89_RS18725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF89_RS18735	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF89_RS18745	COG1668	transmembrane transport
BF89_RS18750	COG1959	2 iron, 2 sulfur cluster binding
BF89_RS18760	COG0697	spore germination
BF89_RS18765	COG1396	sequence-specific DNA binding
BF89_RS18770	COG1983	PspC domain protein
BF89_RS18785	COG3279	Response regulator of the LytR AlgR family
BF89_RS18790	COG3275	phosphorelay sensor kinase activity
BF89_RS18795	COG4608	Belongs to the ABC transporter superfamily
BF89_RS18800	COG0444	Belongs to the ABC transporter superfamily
BF89_RS18810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF89_RS18820	COG0402	S-adenosylhomocysteine deaminase activity
BF89_RS18825	COG0402	S-adenosylhomocysteine deaminase activity
BF89_RS18835	COG2233	PERMEase
BF89_RS18840	COG2197	response regulator
BF89_RS18855	COG1309	transcriptional regulator
BF89_RS18875	COG5401	PFAM Sporulation and spore germination
BF89_RS18890	COG0622	Phosphoesterase
BF89_RS18940	COG1067	ATP-dependent peptidase activity
BF89_RS18940	COG0470	DNA polymerase III
BF89_RS18955	COG1764	response to oxidative stress
BF89_RS18960	COG1846	Transcriptional regulator
BF89_RS18970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF89_RS18980	COG1587	Uroporphyrinogen-III synthase
BF89_RS18985	COG0113	porphobilinogen synthase activity
BF89_RS18995	COG1388	LysM domain
BF89_RS19005	COG0525	valine-tRNA ligase activity
BF89_RS19010	COG0285	dihydrofolate synthase activity
BF89_RS19030	COG1077	Cell shape determining protein MreB Mrl
BF89_RS19050	COG2894	cell division
BF89_RS19055	COG0739	heme binding
BF89_RS19060	COG1994	Peptidase M50
BF89_RS19065	COG1530	ribonuclease E activity
BF89_RS19075	COG2868	ribosomal protein
BF89_RS19085	COG3290	protein histidine kinase activity
BF89_RS19090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF89_RS19095	COG0745	RESPONSE REGULATOR receiver
BF89_RS19105	COG5002	protein histidine kinase activity
BF89_RS19110	COG1136	(ABC) transporter
BF89_RS19115	COG0577	efflux transmembrane transporter activity
BF89_RS19120	COG0577	efflux transmembrane transporter activity
BF89_RS19125	COG0077	Prephenate dehydratase
BF89_RS19130	COG2258	MOSC domain
BF89_RS19135	COG1827	regulation of RNA biosynthetic process
BF89_RS19140	COG1104	cysteine desulfurase activity
BF89_RS19145	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF89_RS19150	COG0157	Belongs to the NadC ModD family
BF89_RS19175	COG0640	Transcriptional regulator
BF89_RS19180	COG0697	spore germination
BF89_RS19185	COG0697	spore germination
BF89_RS19195	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF89_RS19225	COG1862	Preprotein translocase
BF89_RS19235	COG2323	membrane
BF89_RS19240	COG2244	polysaccharide biosynthetic process
BF89_RS19250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF89_RS19250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF89_RS19255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF89_RS19260	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF89_RS19260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF89_RS19270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF89_RS19295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF89_RS19305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF89_RS19310	COG1959	2 iron, 2 sulfur cluster binding
BF89_RS19315	COG1104	cysteine desulfurase activity
BF89_RS19320	COG0482	sulfurtransferase activity
BF89_RS19330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF89_RS19350	COG0628	permease
BF89_RS19360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF89_RS19380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF89_RS19385	COG4122	O-methyltransferase activity
BF89_RS19390	COG0826	peptidase U32
BF89_RS19395	COG0826	peptidase U32
BF89_RS19410	COG0768	penicillin binding
BF89_RS19435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF89_RS19440	COG0626	cystathionine gamma-synthase activity
BF89_RS19445	COG1454	alcohol dehydrogenase
BF89_RS19445	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS19455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS19495	COG2259	Doxx family
BF89_RS19500	COG2514	catechol 2,3-dioxygenase activity
BF89_RS19510	COG3186	Phenylalanine-4-hydroxylase
BF89_RS19515	COG1404	Belongs to the peptidase S8 family
BF89_RS19550	COG2267	carboxylic ester hydrolase activity
BF89_RS19560	COG1785	Belongs to the alkaline phosphatase family
BF89_RS19570	COG2357	RelA SpoT domain protein
BF89_RS19575	COG0778	Nitroreductase
BF89_RS19585	COG1595	DNA-templated transcription, initiation
BF89_RS19610	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF89_RS19615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF89_RS19625	COG1534	Rna-binding protein
BF89_RS19635	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF89_RS19640	COG0799	negative regulation of ribosome biogenesis
BF89_RS19645	COG2226	methyltransferase
BF89_RS19650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_RS19655	COG1596	polysaccharide export
BF89_RS19655	COG1555	photosystem II stabilization
BF89_RS19660	COG2131	deaminase
BF89_RS19675	COG1466	dna polymerase III delta subunit
BF89_RS19700	COG1733	regulation of RNA biosynthetic process
BF89_RS19705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF89_RS19735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF89_RS19740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF89_RS19745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BF89_RS19750	COG1610	YqeY-like protein
BF89_RS19770	COG1702	phosphate starvation-inducible protein PhoH
BF89_RS19775	COG1480	7TM receptor with intracellular HD hydrolase
BF89_RS19785	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF89_RS19790	COG0295	cytidine deaminase activity
BF89_RS19795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF89_RS19810	COG0517	IMP dehydrogenase activity
BF89_RS19830	COG0358	DNA primase activity
BF89_RS19835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF89_RS19840	COG2010	Cytochrome c
BF89_RS19845	COG2384	SAM-dependent methyltransferase
BF89_RS19850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF89_RS19880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS19885	COG1121	(ABC) transporter
BF89_RS19890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF89_RS19895	COG0735	belongs to the Fur family
BF89_RS19920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF89_RS19925	COG0477	Major facilitator Superfamily
BF89_RS19930	COG0768	penicillin binding
BF89_RS19935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF89_RS19940	COG0573	inorganic phosphate transmembrane transporter activity
BF89_RS19945	COG0581	inorganic phosphate transmembrane transporter activity
BF89_RS19955	COG0704	Plays a role in the regulation of phosphate uptake
BF89_RS19960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF89_RS19965	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF89_RS19970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF89_RS19975	COG4483	Protein conserved in bacteria
BF89_RS19980	COG1940	carbohydrate kinase activity
BF89_RS19990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS20015	COG0626	cystathionine gamma-synthase activity
BF89_RS20020	COG0626	cystathionine gamma-synthase activity
BF89_RS20030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF89_RS20030	COG0646	methionine synthase
BF89_RS20040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF89_RS20090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF89_RS20095	COG1459	type II secretion system
BF89_RS20100	COG4537	Required for transformation and DNA binding
BF89_RS20105	COG4970	Tfp pilus assembly protein FimT
BF89_RS20160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF89_RS20190	COG1725	Transcriptional regulator
BF89_RS20195	COG1131	(ABC) transporter
BF89_RS20235	COG2076	Multidrug Resistance protein
BF89_RS20240	COG2076	Multidrug Resistance protein
BF89_RS20250	COG1609	Transcriptional regulator
BF89_RS20255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF89_RS20260	COG0095	Lipoate-protein ligase
BF89_RS20280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF89_RS20290	COG3872	metal-dependent enzyme
BF89_RS20305	COG0006	proline dipeptidase activity
BF89_RS20330	COG3854	ATPases associated with a variety of cellular activities
BF89_RS20375	COG0511	ligase activity, forming carbon-carbon bonds
BF89_RS20380	COG0439	Biotin carboxylase
BF89_RS20385	COG1302	Protein conserved in bacteria
BF89_RS20410	COG0142	geranyltranstransferase activity
BF89_RS20420	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF89_RS20430	COG0497	DNA recombination
BF89_RS20435	COG0750	zinc metalloprotease
BF89_RS20440	COG0745	RESPONSE REGULATOR receiver
BF89_RS20450	COG3093	addiction module antidote protein HigA
BF89_RS20455	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_RS20465	COG3829	transcription factor binding
BF89_RS20465	COG3290	protein histidine kinase activity
BF89_RS20475	COG0280	phosphate acetyltransferase
BF89_RS20490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF89_RS20495	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF89_RS20500	COG0022	dehydrogenase e1 component
BF89_RS20505	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_RS20515	COG0772	Belongs to the SEDS family
BF89_RS20520	COG2816	NAD+ diphosphatase activity
BF89_RS20540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF89_RS20545	COG0765	amino acid transport
BF89_RS20550	COG1126	abc transporter atp-binding protein
BF89_RS20555	COG4129	membrane
BF89_RS20560	COG1376	ErfK ybiS ycfS ynhG family protein
BF89_RS20575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS20580	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF89_RS20590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF89_RS20610	COG1760	l-serine dehydratase
BF89_RS20615	COG1760	l-serine dehydratase
BF89_RS20620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_RS20625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS20630	COG0300	oxidoreductase activity
BF89_RS20645	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF89_RS20655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF89_RS20675	COG1522	sequence-specific DNA binding
BF89_RS20685	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS20690	COG1757	Na H antiporter
BF89_RS20700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF89_RS20715	COG1073	alpha beta
BF89_RS20715	COG2226	methyltransferase
BF89_RS20720	COG4106	trans-aconitate 2-methyltransferase activity
BF89_RS20745	COG0307	riboflavin synthase, alpha
BF89_RS20750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF89_RS20750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF89_RS20765	COG1073	alpha beta
BF89_RS20770	COG0456	acetyltransferase
BF89_RS20775	COG1609	Transcriptional regulator
BF89_RS20780	COG2056	Na+-H+ antiporter family
BF89_RS20785	COG0596	Alpha beta hydrolase
BF89_RS20795	COG1525	nuclease
BF89_RS20795	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS20795	COG4085	toxin activity
BF89_RS20805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF89_RS20805	COG0456	acetyltransferase
BF89_RS20810	COG0656	L-ascorbic acid biosynthetic process
BF89_RS20815	COG0667	Aldo Keto reductase
BF89_RS20835	COG1300	Membrane
BF89_RS20840	COG0735	belongs to the Fur family
BF89_RS20850	COG4974	Belongs to the 'phage' integrase family
BF89_RS20875	COG0598	Magnesium transport protein CorA
BF89_RS20890	COG1846	Transcriptional regulator
BF89_RS20910	COG1131	(ABC) transporter
BF89_RS20915	COG1725	Transcriptional regulator
BF89_RS20920	COG1686	Belongs to the peptidase S11 family
BF89_RS20940	COG0733	neurotransmitter:sodium symporter activity
BF89_RS20965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_RS20980	COG0697	spore germination
BF89_RS20985	COG0561	phosphatase activity
BF89_RS20990	COG4086	secreted protein
BF89_RS20995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF89_RS21005	COG0456	acetyltransferase
BF89_RS21040	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF89_RS21050	COG2188	Transcriptional regulator
BF89_RS21060	COG3711	transcriptional antiterminator
BF89_RS21065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF89_RS21065	COG2190	(PTS) system
BF89_RS21065	COG1263	PTS System
BF89_RS21090	COG0778	Nitroreductase
BF89_RS21095	COG2199	diguanylate cyclase activity
BF89_RS21115	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF89_RS21135	COG0436	Aminotransferase
BF89_RS21140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF89_RS21150	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BF89_RS21160	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS21165	COG1695	Transcriptional regulator
BF89_RS21205	COG0183	Belongs to the thiolase family
BF89_RS21245	COG3842	ATPase activity
BF89_RS21250	COG0366	Alpha amylase catalytic
BF89_RS21260	COG2182	Extracellular solute-binding protein
BF89_RS21265	COG1175	transmembrane transport
BF89_RS21270	COG3833	ABC-type maltose transport systems, permease component
BF89_RS21275	COG1609	Transcriptional regulator
BF89_RS21280	COG0436	Aminotransferase
BF89_RS21290	COG2205	protein histidine kinase activity
BF89_RS21300	COG3209	COG3209 Rhs family protein
BF89_RS21325	COG2814	Major facilitator Superfamily
BF89_RS21375	COG1408	metallophosphoesterase
BF89_RS21380	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS21385	COG2200	EAL domain
BF89_RS21400	COG4703	Protein of unknown function (DUF1797)
BF89_RS21410	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF89_RS21420	COG0517	IMP dehydrogenase activity
BF89_RS21425	COG0583	DNA-binding transcription factor activity
BF89_RS21445	COG0569	domain protein
BF89_RS21450	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF89_RS21460	COG0561	phosphatase activity
BF89_RS21465	COG0242	peptide deformylase activity
BF89_RS21475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF89_RS21480	COG0022	dehydrogenase e1 component
BF89_RS21530	COG1982	Orn Lys Arg decarboxylase major
BF89_RS21550	COG0483	inositol monophosphate 1-phosphatase activity
BF89_RS21560	COG1217	gtp-binding protein TYPA
BF89_RS21575	COG4896	Protein conserved in bacteria
BF89_RS21585	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF89_RS21590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF89_RS21600	COG0772	Belongs to the SEDS family
BF89_RS21605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF89_RS21640	COG3336	cytochrome c oxidase
BF89_RS21655	COG2340	Cysteine-rich secretory protein family
BF89_RS21670	COG0406	alpha-ribazole phosphatase activity
BF89_RS21675	COG3679	Belongs to the UPF0342 family
BF89_RS21690	COG0742	ribosomal rna small subunit methyltransferase
BF89_RS21700	COG3314	Sporulation integral membrane protein YlbJ
BF89_RS21705	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF89_RS21710	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF89_RS21720	COG0582	viral genome integration into host DNA
BF89_RS21735	COG1396	sequence-specific DNA binding
BF89_RS21745	COG1396	sequence-specific DNA binding
BF89_RS21775	COG1484	DNA-dependent DNA replication
BF89_RS21810	COG0756	dUTP diphosphatase activity
BF89_RS21880	COG0582	viral genome integration into host DNA
BF89_RS21905	COG4626	Terminase
BF89_RS21905	COG1802	Transcriptional regulator
BF89_RS22000	COG4824	toxin secretion phage lysis holin
BF89_RS22050	COG1399	metal-binding, possibly nucleic acid-binding protein
BF89_RS22055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BF89_RS22070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF89_RS22085	COG4839	cell division protein FtsL
BF89_RS22090	COG0768	penicillin binding
BF89_RS22095	COG0768	penicillin binding
BF89_RS22100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF89_RS22115	COG0772	Belongs to the SEDS family
BF89_RS22125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF89_RS22130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF89_RS22135	COG0849	cell division
BF89_RS22140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF89_RS22150	COG1191	sigma factor activity
BF89_RS22155	COG1191	sigma factor activity
BF89_RS22160	COG1873	PFAM PRC-barrel domain
BF89_RS22165	COG1496	oxidoreductase activity
BF89_RS22170	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF89_RS22180	COG0762	integral membrane protein
BF89_RS22185	COG2302	S4 RNA-binding domain
BF89_RS22190	COG3599	regulation of cell shape
BF89_RS22210	COG0564	pseudouridine synthase activity
BF89_RS22275	COG3069	C4-dicarboxylate transmembrane transporter activity
BF89_RS22290	COG0006	proline dipeptidase activity
BF89_RS22300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF89_RS22305	COG1561	YicC-like family, N-terminal region
BF89_RS22325	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF89_RS22330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF89_RS22335	COG0242	peptide deformylase activity
BF89_RS22345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF89_RS22345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF89_RS22355	COG0631	protein serine/threonine phosphatase activity
BF89_RS22360	COG2815	serine threonine protein kinase
BF89_RS22360	COG0515	serine threonine protein kinase
BF89_RS22365	COG1162	GTPase activity
BF89_RS22370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF89_RS22375	COG1564	THIamine pyrophosphokinase
BF89_RS22390	COG1302	Protein conserved in bacteria
BF89_RS22395	COG1461	Dihydroxyacetone kinase
BF89_RS22400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF89_RS22415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF89_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS22425	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF89_RS22435	COG1196	nuclear chromosome segregation
BF89_RS22440	COG0552	protein localization to endoplasmic reticulum
BF89_RS22450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF89_RS22460	COG1837	Belongs to the UPF0109 family
BF89_RS22500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF89_RS22510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF89_RS22520	COG4974	Belongs to the 'phage' integrase family
BF89_RS22550	COG0528	UMP kinase activity
BF89_RS22565	COG4589	Belongs to the CDS family
BF89_RS22575	COG0750	zinc metalloprotease
BF89_RS22595	COG0195	Participates in both transcription termination and antitermination
BF89_RS22600	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF89_RS22605	COG1358	cellular component organization or biogenesis
BF89_RS22615	COG1550	Protein conserved in bacteria
BF89_RS22625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF89_RS22630	COG0196	riboflavin kinase activity
BF89_RS22645	COG0726	polysaccharide deacetylase
BF89_RS22650	COG0612	Peptidase, M16
BF89_RS22655	COG1873	PFAM PRC-barrel domain
BF89_RS22660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF89_RS22665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF89_RS22670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF89_RS22675	COG0527	aspartate kinase activity
BF89_RS22690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF89_RS22695	COG0740	serine-type endopeptidase activity
BF89_RS22705	COG1674	ftsk spoiiie
BF89_RS22710	COG2188	Transcriptional regulator
BF89_RS22715	COG1744	ABC transporter substrate-binding protein PnrA-like
BF89_RS22720	COG3845	ABC transporter
BF89_RS22725	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF89_RS22730	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF89_RS22735	COG1079	Belongs to the binding-protein-dependent transport system permease family
BF89_RS22740	COG0612	Peptidase, M16
BF89_RS22745	COG0612	Peptidase, M16
BF89_RS22750	COG0300	oxidoreductase activity
BF89_RS22765	COG1426	Protein conserved in bacteria
BF89_RS22770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF89_RS22795	COG1692	metallophosphoesterase
BF89_RS22800	COG2359	stage V sporulation protein S
BF89_RS22810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF89_RS22810	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF89_RS22815	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF89_RS22820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF89_RS22825	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF89_RS22845	COG1131	(ABC) transporter
BF89_RS22870	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF89_RS22880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF89_RS22885	COG1368	sulfuric ester hydrolase activity
BF89_RS22890	COG0562	UDP-galactopyranose mutase
BF89_RS22895	COG3773	Cell wall hydrolase
BF89_RS22900	COG1404	Belongs to the peptidase S8 family
BF89_RS22915	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF89_RS22920	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_RS22920	COG0596	Alpha beta hydrolase
BF89_RS22925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS22930	COG1380	Effector of murein hydrolase LrgA
BF89_RS22935	COG1346	cytolysis
BF89_RS22960	COG0346	lactoylglutathione lyase activity
BF89_RS22965	COG2267	carboxylic ester hydrolase activity
BF89_RS22980	COG2364	Membrane
BF89_RS22990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF89_RS22995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF89_RS23000	COG2169	Transcriptional regulator
BF89_RS23015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS23020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS23025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS23030	COG1120	ATPase activity
BF89_RS23035	COG2819	hydrolase of the alpha beta superfamily
BF89_RS23045	COG1937	Protein conserved in bacteria
BF89_RS23050	COG2608	mercury ion transmembrane transporter activity
BF89_RS23055	COG2217	Heavy metal translocating P-type atpase
BF89_RS23065	COG2116	formate transmembrane transporter activity
BF89_RS23070	COG1408	metallophosphoesterase
BF89_RS23080	COG1113	amino acid transport
BF89_RS23095	COG2322	membrane
BF89_RS23105	COG1349	DNA-binding transcription factor activity
BF89_RS23110	COG1105	Belongs to the carbohydrate kinase PfkB family
BF89_RS23115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF89_RS23115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF89_RS23115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF89_RS23120	COG3584	3D domain protein
BF89_RS23120	COG1388	LysM domain
BF89_RS23150	COG0464	growth
BF89_RS23155	COG2860	membrane
BF89_RS23160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF89_RS23165	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF89_RS23170	COG0789	Transcriptional regulator
BF89_RS23175	COG0174	glutamine synthetase
BF89_RS23200	COG1396	sequence-specific DNA binding
BF89_RS23280	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF89_RS23325	COG1595	DNA-templated transcription, initiation
BF89_RS23485	COG4824	toxin secretion phage lysis holin
BF89_RS23490	COG1388	LysM domain
BF89_RS23490	COG3409	Peptidoglycan-binding domain 1 protein
BF89_RS23490	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_RS23525	COG1695	Transcriptional regulator
BF89_RS23545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF89_RS23555	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS23570	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF89_RS23575	COG3639	organic phosphonate transmembrane transporter activity
BF89_RS23610	COG1132	(ABC) transporter
BF89_RS23615	COG1132	(ABC) transporter
BF89_RS23630	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF89_RS23630	COG3409	Peptidoglycan-binding domain 1 protein
BF89_RS23640	COG0730	response to heat
BF89_RS23655	COG1346	cytolysis
BF89_RS23660	COG1380	Effector of murein hydrolase LrgA
BF89_RS23665	COG0583	DNA-binding transcription factor activity
BF89_RS23675	COG0785	Cytochrome C biogenesis protein
BF89_RS23680	COG4846	Membrane protein involved in cytochrome C biogenesis
BF89_RS23735	COG2226	methyltransferase
BF89_RS23760	COG0010	Belongs to the arginase family
BF89_RS23765	COG1329	Transcriptional regulator
BF89_RS23770	COG1902	pentaerythritol trinitrate reductase activity
BF89_RS23775	COG0069	glutamate synthase activity
BF89_RS23780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF89_RS23785	COG0346	lactoylglutathione lyase activity
BF89_RS23790	COG0400	carboxylic ester hydrolase activity
BF89_RS23795	COG5002	protein histidine kinase activity
BF89_RS23805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS23850	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_RS23855	COG1268	BioY protein
BF89_RS23860	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_RS23865	COG0183	Belongs to the thiolase family
BF89_RS23880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF89_RS23890	COG2211	Major facilitator Superfamily
BF89_RS23920	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF89_RS23925	COG2274	protein secretion by the type I secretion system
BF89_RS23935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF89_RS23965	COG0824	Thioesterase
BF89_RS23970	COG4841	protein insertion into membrane
BF89_RS23975	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF89_RS23990	COG0745	RESPONSE REGULATOR receiver
BF89_RS23995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF89_RS24000	COG1832	CoA-binding protein
BF89_RS24010	COG0187	DNA topoisomerase II activity
BF89_RS24015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF89_RS24020	COG0673	inositol 2-dehydrogenase activity
BF89_RS24030	COG1131	(ABC) transporter
BF89_RS24055	COG1595	DNA-templated transcription, initiation
BF89_RS24065	COG1316	TRANSCRIPTIONal
BF89_RS24070	COG1301	dicarboxylic acid transport
BF89_RS24075	COG4166	transmembrane transport
BF89_RS24080	COG4166	transmembrane transport
BF89_RS24085	COG2226	methyltransferase
BF89_RS24125	COG0697	spore germination
BF89_RS24140	COG2427	Protein of unknown function (DUF1641)
BF89_RS24145	COG5609	conserved protein (DUF2294)
BF89_RS24150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF89_RS24160	COG2116	formate transmembrane transporter activity
BF89_RS24165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF89_RS24170	COG0303	'Molybdopterin
BF89_RS24175	COG0314	molybdopterin synthase activity
BF89_RS24185	COG0489	protein tyrosine kinase activity
BF89_RS24200	COG3326	Membrane
BF89_RS24205	COG2962	Rard protein
BF89_RS24210	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF89_RS24215	COG1657	PFAM Prenyltransferase squalene oxidase
BF89_RS24225	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS24230	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS24240	COG4145	pantothenate transmembrane transporter activity
BF89_RS24265	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS24295	COG0716	FMN binding
BF89_RS24335	COG2720	vancomycin resistance protein
BF89_RS24340	COG2514	catechol 2,3-dioxygenase activity
BF89_RS24350	COG1285	pathogenesis
BF89_RS24360	COG1024	Enoyl-CoA hydratase
BF89_RS24365	COG1216	Glycosyl transferase, family 2
BF89_RS24395	COG0277	FAD linked oxidase domain protein
BF89_RS24400	COG0385	Bile acid
BF89_RS24415	COG2808	Putative FMN-binding domain
BF89_RS24435	COG0604	alcohol dehydrogenase
BF89_RS24440	COG0640	Transcriptional regulator
BF89_RS24465	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_RS24495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_RS24500	COG1164	Oligoendopeptidase f
BF89_RS24505	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF89_RS24520	COG1193	negative regulation of DNA recombination
BF89_RS24540	COG0583	DNA-binding transcription factor activity
BF89_RS24570	COG0384	phenazine biosynthesis protein PhzF
BF89_RS24575	COG3739	integral membrane protein
BF89_RS24580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS24585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF89_RS24595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS24615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF89_RS24620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF89_RS24655	COG2814	Major facilitator Superfamily
BF89_RS24660	COG1113	amino acid transport
BF89_RS24665	COG0604	alcohol dehydrogenase
BF89_RS24700	COG2072	flavoprotein involved in K transport
BF89_RS24735	COG3409	Peptidoglycan-binding domain 1 protein
BF89_RS24735	COG3757	hydrolase, family 25
BF89_RS24740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS24750	COG1151	hydroxylamine reductase activity
BF89_RS24775	COG3152	Membrane
BF89_RS24795	COG1309	transcriptional regulator
BF89_RS24810	COG1191	sigma factor activity
BF89_RS24840	COG1733	regulation of RNA biosynthetic process
BF89_RS24850	COG0318	PFAM AMP-dependent synthetase and ligase
BF89_RS24860	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS24870	COG0384	phenazine biosynthesis protein PhzF
BF89_RS24890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS24905	COG1733	regulation of RNA biosynthetic process
BF89_RS24910	COG1733	regulation of RNA biosynthetic process
BF89_RS24915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF89_RS24920	COG0673	inositol 2-dehydrogenase activity
BF89_RS24925	COG2188	Transcriptional regulator
BF89_RS24930	COG1733	regulation of RNA biosynthetic process
BF89_RS24940	COG1393	Belongs to the ArsC family
BF89_RS24965	COG0814	amino acid
BF89_RS24970	COG0346	lactoylglutathione lyase activity
BF89_RS24985	COG2814	Major facilitator Superfamily
BF89_RS24990	COG0656	L-ascorbic acid biosynthetic process
BF89_RS25015	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS25025	COG3321	synthase
BF89_RS25025	COG0604	alcohol dehydrogenase
BF89_RS25035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF89_RS25040	COG0604	alcohol dehydrogenase
BF89_RS25045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF89_RS25060	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF89_RS25065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF89_RS25075	COG1070	Carbohydrate kinase
BF89_RS25080	COG2706	6-phosphogluconolactonase activity
BF89_RS25085	COG3813	Protein conserved in bacteria
BF89_RS25090	COG1357	PFAM Pentapeptide repeats (8 copies)
BF89_RS25095	COG0697	spore germination
BF89_RS25100	COG0789	Transcriptional regulator
BF89_RS25105	COG1253	flavin adenine dinucleotide binding
BF89_RS25135	COG0477	Major facilitator Superfamily
BF89_RS25145	COG2226	methyltransferase
BF89_RS25165	COG0628	permease
BF89_RS25170	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF89_RS25180	COG0577	efflux transmembrane transporter activity
BF89_RS25180	COG1136	(ABC) transporter
BF89_RS25190	COG0110	maltose O-acetyltransferase activity
BF89_RS25195	COG0738	Major facilitator superfamily
BF89_RS25200	COG1940	carbohydrate kinase activity
BF89_RS25205	COG0346	lactoylglutathione lyase activity
BF89_RS25230	COG2365	Tyrosine phosphatase family
BF89_RS25240	COG1011	Hydrolase
BF89_RS25265	COG1131	(ABC) transporter
BF89_RS25275	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS25295	COG0778	Nitroreductase
BF89_RS25300	COG1733	regulation of RNA biosynthetic process
BF89_RS25315	COG0124	histidyl-tRNA synthetase
BF89_RS25320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF89_RS25325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF89_RS25330	COG3620	sequence-specific DNA binding
BF89_RS25345	COG2356	endonuclease I
BF89_RS25350	COG1288	antiporter activity
BF89_RS25355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF89_RS25370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF89_RS25375	COG1122	ATPase activity
BF89_RS25405	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF89_RS25415	COG2031	fatty acid transporter
BF89_RS25430	COG1309	transcriptional regulator
BF89_RS25435	COG2076	Multidrug Resistance protein
BF89_RS25455	COG1131	(ABC) transporter
BF89_RS25460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF89_RS25475	COG2814	Major facilitator Superfamily
BF89_RS25480	COG1846	Transcriptional regulator
BF89_RS25490	COG0477	Major facilitator Superfamily
BF89_RS25545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF89_RS25545	COG2207	Transcriptional regulator
BF89_RS25555	COG0662	Cupin 2, conserved barrel domain protein
BF89_RS25570	COG1595	DNA-templated transcription, initiation
BF89_RS25590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF89_RS25605	COG0531	amino acid
BF89_RS25610	COG1522	sequence-specific DNA binding
BF89_RS25625	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF89_RS25630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF89_RS25640	COG1760	l-serine dehydratase
BF89_RS25645	COG1760	l-serine dehydratase
BF89_RS25650	COG0814	amino acid
BF89_RS25665	COG1309	transcriptional regulator
BF89_RS25670	COG2814	Major facilitator Superfamily
BF89_RS25685	COG0534	Mate efflux family protein
BF89_RS25715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF89_RS25735	COG0457	Tetratricopeptide repeat
BF89_RS25740	COG1609	Transcriptional regulator
BF89_RS25750	COG0561	phosphatase activity
BF89_RS25755	COG0673	inositol 2-dehydrogenase activity
BF89_RS25785	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF89_RS25795	COG0583	DNA-binding transcription factor activity
BF89_RS25805	COG1139	Iron-sulfur cluster binding protein
BF89_RS25810	COG1556	Lactate utilization protein
BF89_RS25815	COG2271	Major facilitator Superfamily
BF89_RS25820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF89_RS25825	COG2808	Putative FMN-binding domain
BF89_RS25835	COG1846	Transcriptional regulator
BF89_RS25840	COG2364	Membrane
BF89_RS25850	COG3850	Histidine kinase
BF89_RS25850	COG5002	protein histidine kinase activity
BF89_RS25870	COG0577	efflux transmembrane transporter activity
BF89_RS25875	COG1136	(ABC) transporter
BF89_RS25890	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF89_RS25895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF89_RS25905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF89_RS25910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS25925	COG1476	TRANSCRIPTIONal
BF89_RS25950	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF89_RS25980	COG3850	Histidine kinase
BF89_RS25980	COG5002	protein histidine kinase activity
BF89_RS25985	COG0745	RESPONSE REGULATOR receiver
BF89_RS26010	COG2814	Major facilitator Superfamily
BF89_RS26055	COG2169	Transcriptional regulator
BF89_RS26075	COG0346	lactoylglutathione lyase activity
BF89_RS26090	COG1522	sequence-specific DNA binding
BF89_RS26105	COG0443	Heat shock 70 kDa protein
BF89_RS26120	COG0640	Transcriptional regulator
BF89_RS26125	COG0346	lactoylglutathione lyase activity
BF89_RS26130	COG0798	PFAM Bile acid sodium symporter
BF89_RS26160	COG1121	(ABC) transporter
BF89_RS26165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF89_RS26170	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF89_RS26175	COG2267	carboxylic ester hydrolase activity
BF89_RS26180	COG1575	Belongs to the MenA family. Type 1 subfamily
BF89_RS26190	COG5609	conserved protein (DUF2294)
BF89_RS26195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF89_RS26205	COG0288	reversible hydration of carbon dioxide
BF89_RS26210	COG0415	Belongs to the DNA photolyase family
BF89_RS26245	COG0598	Magnesium transport protein CorA
BF89_RS26255	COG0583	DNA-binding transcription factor activity
BF89_RS26275	COG1335	isochorismatase
BF89_RS26280	COG2267	carboxylic ester hydrolase activity
BF89_RS26285	COG0753	catalase activity
BF89_RS26290	COG0737	Belongs to the 5'-nucleotidase family
BF89_RS26315	COG1115	amino acid carrier protein
BF89_RS26320	COG2066	Belongs to the glutaminase family
BF89_RS26330	COG0784	Response regulator, receiver
BF89_RS26335	COG0697	spore germination
BF89_RS26340	COG0531	amino acid
BF89_RS26355	COG0281	malic enzyme
BF89_RS26365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_RS26370	COG1114	Component of the transport system for branched-chain amino acids
BF89_RS26375	COG0531	amino acid
BF89_RS26380	COG0322	excinuclease ABC activity
BF89_RS26390	COG1396	sequence-specific DNA binding
BF89_RS26395	COG0252	asparaginase activity
BF89_RS26400	COG1027	Aspartate ammonia-lyase
BF89_RS26415	COG1063	alcohol dehydrogenase
BF89_RS26450	COG1280	lysine exporter protein (LysE YggA)
BF89_RS26455	COG3403	YqcI/YcgG family
BF89_RS26460	COG5577	PFAM Coat F domain
BF89_RS26475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF89_RS26480	COG0574	Belongs to the PEP-utilizing enzyme family
BF89_RS26480	COG3848	Pyruvate phosphate dikinase
BF89_RS26495	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF89_RS26510	COG3314	Sporulation integral membrane protein YlbJ
BF89_RS26530	COG1960	acyl-CoA dehydrogenase activity
BF89_RS26540	COG0640	Transcriptional regulator
BF89_RS26545	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF89_RS26560	COG1414	Transcriptional regulator
BF89_RS26565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF89_RS26600	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF89_RS26610	COG0768	penicillin binding
BF89_RS26650	COG4335	DNA alkylation repair
BF89_RS26660	COG0833	amino acid
BF89_RS26670	COG0730	response to heat
BF89_RS26700	COG0596	Alpha beta hydrolase
BF89_RS26705	COG0745	RESPONSE REGULATOR receiver
BF89_RS26710	COG0642	Histidine kinase
BF89_RS26730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS26750	COG0456	acetyltransferase
BF89_RS26755	COG2207	Transcriptional regulator
BF89_RS26780	COG1136	(ABC) transporter
BF89_RS26780	COG0577	efflux transmembrane transporter activity
BF89_RS26790	COG1725	Transcriptional regulator
BF89_RS26825	COG1846	Transcriptional regulator
BF89_RS26830	COG0778	Nitroreductase
BF89_RS26840	COG0714	Associated with various cellular activities
BF89_RS26865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF89_RS26875	COG0753	catalase activity
BF89_RS26880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF89_RS26890	COG0463	Glycosyl transferase, family 2
BF89_RS26940	COG0714	Associated with various cellular activities
BF89_RS26960	COG0346	lactoylglutathione lyase activity
BF89_RS26965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS26975	COG3279	Response regulator of the LytR AlgR family
BF89_RS26985	COG4377	Putative membrane peptidase family (DUF2324)
BF89_RS27000	COG3655	Transcriptional regulator
BF89_RS27010	COG1785	Belongs to the alkaline phosphatase family
BF89_RS27015	COG3239	Fatty acid desaturase
BF89_RS27020	COG1690	Belongs to the RtcB family
BF89_RS27025	COG0833	amino acid
BF89_RS27030	COG1414	Transcriptional regulator
BF89_RS27035	COG4187	Peptidase family M20/M25/M40
BF89_RS27040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF89_RS27045	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF89_RS27055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF89_RS27075	COG2329	Antibiotic biosynthesis monooxygenase
BF89_RS27105	COG1070	Carbohydrate kinase
BF89_RS27110	COG2390	Transcriptional regulator
BF89_RS27120	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF89_RS27130	COG1879	ABC-type sugar transport system periplasmic component
BF89_RS27155	COG1595	DNA-templated transcription, initiation
BF89_RS27165	COG3584	3D domain protein
BF89_RS27165	COG1388	LysM domain
BF89_RS27200	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF89_RS27200	COG1605	Chorismate mutase
BF89_RS27205	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF89_RS27210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF89_RS27215	COG0287	Prephenate dehydrogenase
BF89_RS27230	COG1309	transcriptional regulator
BF89_RS27235	COG2409	Drug exporters of the RND superfamily
BF89_RS27235	COG1033	growth of symbiont in host cell
BF89_RS27240	COG2409	Drug exporters of the RND superfamily
BF89_RS27240	COG1033	growth of symbiont in host cell
BF89_RS27250	COG0488	(ABC) transporter
BF89_RS27255	COG1368	sulfuric ester hydrolase activity
BF89_RS27260	COG0861	Integral membrane protein TerC family
BF89_RS27300	COG2318	DinB family
BF89_RS27305	COG0697	spore germination
BF89_RS27330	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF89_RS27350	COG2816	NAD+ diphosphatase activity
BF89_RS27370	COG1116	anion transmembrane transporter activity
BF89_RS27375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF89_RS27380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF89_RS27385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF89_RS27400	COG0628	permease
BF89_RS27450	COG1131	(ABC) transporter
BF89_RS27470	COG5146	pantothenate kinase activity
BF89_RS27475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF89_RS27480	COG0436	Aminotransferase
BF89_RS27515	COG2226	methyltransferase
BF89_RS27530	COG2261	transglycosylase associated protein
BF89_RS27550	COG0477	Major facilitator Superfamily
BF89_RS27550	COG2814	Major facilitator Superfamily
BF89_RS27555	COG4533	DNA binding
BF89_RS27560	COG0789	Transcriptional regulator
BF89_RS27565	COG1664	Polymer-forming cytoskeletal
BF89_RS27575	COG2814	Major facilitator Superfamily
BF89_RS27595	COG1307	EDD domain protein, DegV family
BF89_RS27635	COG0745	RESPONSE REGULATOR receiver
BF89_RS27640	COG5002	protein histidine kinase activity
BF89_RS27645	COG2936	dipeptidyl-peptidase activity
BF89_RS27685	COG4948	Mandelate Racemase Muconate Lactonizing
BF89_RS27695	COG4166	transmembrane transport
BF89_RS27700	COG0519	Catalyzes the synthesis of GMP from XMP
BF89_RS27705	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF89_RS27720	COG0586	Pfam SNARE associated Golgi protein
BF89_RS27760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_RS27765	COG3938	Belongs to the proline racemase family
BF89_RS27775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF89_RS27780	COG1012	belongs to the aldehyde dehydrogenase family
BF89_RS27785	COG1115	amino acid carrier protein
BF89_RS27790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF89_RS27800	COG3397	chitin binding
BF89_RS27825	COG4637	Psort location Cytoplasmic, score
BF89_RS27855	COG0514	ATP-dependent DNA helicase (RecQ)
BF89_RS27860	COG2105	PFAM AIG2 family protein
BF89_RS27875	COG3973	AAA domain
BF89_RS27925	COG2333	competence protein COMEC
BF89_RS27925	COG0658	competence protein
BF89_RS27955	COG2205	protein histidine kinase activity
BF89_RS27970	COG3397	chitin binding
BF89_RS27975	COG2153	protein acetylation
BF89_RS27980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF89_RS28005	COG0517	IMP dehydrogenase activity
BF89_RS28005	COG4175	Glycine betaine
BF89_RS28010	COG4176	ABC-type proline glycine betaine transport system permease component
BF89_RS28045	COG0456	acetyltransferase
BF89_RS28045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF89_RS28050	COG1028	Short-chain dehydrogenase reductase Sdr
BF89_RS28060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF89_RS28065	COG0022	dehydrogenase e1 component
BF89_RS28070	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF89_RS28075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF89_RS28090	COG1959	2 iron, 2 sulfur cluster binding
BF89_RS28110	COG1349	DNA-binding transcription factor activity
BF89_RS28130	COG3284	Transcriptional regulator
BF89_RS28160	COG1309	transcriptional regulator
BF89_RS28165	COG3844	kynureninase activity
BF89_RS28170	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF89_RS28175	COG3483	tryptophan 2,3-dioxygenase activity
BF89_RS28195	COG2959	enzyme of heme biosynthesis
BF89_RS28210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF89_RS28215	COG4129	membrane
BF89_RS28245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS28250	COG0697	spore germination
BF89_RS28260	COG0201	protein transport
BF89_RS28280	COG3227	Zinc metalloprotease (Elastase)
BF89_RS28285	COG1523	belongs to the glycosyl hydrolase 13 family
BF89_RS28300	COG0076	glutamate decarboxylase activity
BF89_RS28305	COG0657	acetylesterase activity
BF89_RS28320	COG1011	Hydrolase
BF89_RS28345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF89_RS28385	COG0322	excinuclease ABC activity
BF89_RS28400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF89_RS28425	COG4667	esterase of the alpha-beta hydrolase superfamily
BF89_RS28455	COG3878	Protein conserved in bacteria
BF89_RS28490	COG1051	belongs to the nudix hydrolase family
BF89_RS28495	COG0592	DNA-directed DNA polymerase activity
BF89_RS28500	COG2816	NAD+ diphosphatase activity
BF89_RS28515	COG2223	nitrite transmembrane transporter activity
BF89_RS28525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_RS28550	COG0697	spore germination
BF89_RS28570	COG0584	glycerophosphoryl diester phosphodiesterase
BF89_RS28585	COG2814	Major facilitator Superfamily
BF89_RS28615	COG0693	protein deglycase activity
BF89_RS28650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF89_RS28660	COG0768	penicillin binding
BF89_RS28665	COG0604	alcohol dehydrogenase
BF89_RS28670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF89_RS28680	COG2205	protein histidine kinase activity
BF89_RS28690	COG1122	ATPase activity
BF89_RS28700	COG1794	racemase activity, acting on amino acids and derivatives
BF89_RS28705	COG1819	glycosyl
BF89_RS28710	COG0768	penicillin binding
BF89_RS28715	COG5002	protein histidine kinase activity
BF89_RS28725	COG0561	phosphatase activity
BF89_RS28765	COG2124	cytochrome p450
BF89_RS28840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF89_RS28850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS28855	COG0460	homoserine dehydrogenase
BF89_RS28880	COG1136	(ABC) transporter
BF89_RS28895	COG0488	(ABC) transporter
BF89_RS28910	COG0745	RESPONSE REGULATOR receiver
BF89_RS28920	COG3773	Cell wall hydrolase
BF89_RS28935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF89_RS28940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF89_RS28955	COG1063	alcohol dehydrogenase
BF89_RS28970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF89_RS28990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF89_RS29010	COG2814	Major facilitator Superfamily
BF89_RS29035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF89_RS29035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF89_RS29075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF89_RS29100	COG1686	Belongs to the peptidase S11 family
BF89_RS29105	COG2318	DinB family
BF89_RS29115	COG0572	uridine kinase
BF89_RS29120	COG1247	-acetyltransferase
BF89_RS29170	COG2376	Dihydroxyacetone kinase