locus-tag	class	description
KM406_RS00010	COG0592	DNA-directed DNA polymerase activity
KM406_RS00015	COG2501	S4 domain
KM406_RS00025	COG0187	DNA topoisomerase II activity
KM406_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM406_RS00065	COG0516	GMP reductase activity
KM406_RS00065	COG0517	IMP dehydrogenase activity
KM406_RS00070	COG1686	Belongs to the peptidase S11 family
KM406_RS00100	COG1428	Deoxynucleoside kinase
KM406_RS00105	COG1428	Deoxynucleoside kinase
KM406_RS00110	COG1335	isochorismatase
KM406_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM406_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM406_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM406_RS00190	COG0470	DNA polymerase III
KM406_RS00195	COG1774	PSP1 C-terminal conserved region
KM406_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM406_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM406_RS00220	COG2002	toxin-antitoxin pair type II binding
KM406_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM406_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM406_RS00230	COG0084	hydrolase, TatD family'
KM406_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM406_RS00250	COG4466	Protein conserved in bacteria
KM406_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM406_RS00270	COG0251	oxidation-reduction process
KM406_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM406_RS00305	COG2002	toxin-antitoxin pair type II binding
KM406_RS00310	COG2244	polysaccharide biosynthetic process
KM406_RS00315	COG3956	TIGRFAM MazG family protein
KM406_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM406_RS00340	COG1098	S1 RNA binding domain
KM406_RS00355	COG2208	phosphoserine phosphatase activity
KM406_RS00360	COG0037	tRNA processing
KM406_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM406_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM406_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM406_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM406_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM406_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM406_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM406_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM406_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM406_RS00420	COG1396	sequence-specific DNA binding
KM406_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM406_RS00455	COG3880	PFAM UvrB UvrC protein
KM406_RS00465	COG0542	response to heat
KM406_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM406_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM406_RS00500	COG1045	serine acetyltransferase
KM406_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM406_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM406_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM406_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM406_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM406_RS00565	COG2813	Specifically methylates the guanine in position
KM406_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM406_RS00580	COG1358	cellular component organization or biogenesis
KM406_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM406_RS00710	COG0201	protein transport
KM406_RS00720	COG0024	Methionine aminopeptidase
KM406_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM406_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM406_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM406_RS00795	COG0489	protein tyrosine kinase activity
KM406_RS00805	COG2194	sulfuric ester hydrolase activity
KM406_RS00810	COG0726	polysaccharide deacetylase
KM406_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM406_RS00895	COG4856	YbbR-like protein
KM406_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM406_RS00915	COG0596	Alpha beta hydrolase
KM406_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM406_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM406_RS00940	COG1506	peptidase
KM406_RS00940	COG4946	Tricorn protease homolog
KM406_RS00975	COG2011	ABC-type metal ion transport system permease component
KM406_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM406_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM406_RS00990	COG0604	alcohol dehydrogenase
KM406_RS01000	COG0277	FAD linked oxidase domain protein
KM406_RS01005	COG2271	Major facilitator Superfamily
KM406_RS01015	COG2814	Major facilitator Superfamily
KM406_RS01030	COG0601	transmembrane transport
KM406_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM406_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM406_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM406_RS01050	COG4166	transmembrane transport
KM406_RS01060	COG2207	Transcriptional regulator
KM406_RS01075	COG4166	transmembrane transport
KM406_RS01080	COG4166	transmembrane transport
KM406_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM406_RS01105	COG4149	molybdate abc transporter
KM406_RS01115	COG1910	domain protein
KM406_RS01125	COG0583	DNA-binding transcription factor activity
KM406_RS01130	COG0697	spore germination
KM406_RS01145	COG0204	Acyl-transferase
KM406_RS01155	COG1609	Transcriptional regulator
KM406_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS01175	COG0084	hydrolase, TatD family'
KM406_RS01180	COG5298	Protein conserved in bacteria
KM406_RS01205	COG0488	(ABC) transporter
KM406_RS01220	COG0747	negative chemotaxis
KM406_RS01225	COG0601	transmembrane transport
KM406_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM406_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM406_RS01240	COG4608	Belongs to the ABC transporter superfamily
KM406_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM406_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM406_RS01290	COG2814	Major facilitator Superfamily
KM406_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM406_RS01310	COG4294	response to UV
KM406_RS01315	COG0457	Tetratricopeptide repeat
KM406_RS01315	COG0705	Rhomboid family
KM406_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM406_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM406_RS01335	COG0864	Transcriptional regulator
KM406_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM406_RS01345	COG2183	response to ionizing radiation
KM406_RS01440	COG0802	atpase or kinase
KM406_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
KM406_RS01450	COG0456	acetyltransferase
KM406_RS01460	COG0488	(ABC) transporter
KM406_RS01475	COG1266	CAAX protease self-immunity
KM406_RS01495	COG2252	PERMEase
KM406_RS01505	COG5002	protein histidine kinase activity
KM406_RS01535	COG2226	methyltransferase
KM406_RS01580	COG1968	undecaprenyl-diphosphatase activity
KM406_RS01595	COG2205	protein histidine kinase activity
KM406_RS01600	COG0745	RESPONSE REGULATOR receiver
KM406_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM406_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM406_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM406_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM406_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM406_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM406_RS01680	COG0151	Belongs to the GarS family
KM406_RS01705	COG0210	DNA helicase
KM406_RS01715	COG4851	CamS sex pheromone cAM373 precursor
KM406_RS01735	COG1335	isochorismatase
KM406_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM406_RS01745	COG2011	ABC-type metal ion transport system permease component
KM406_RS01750	COG1464	Belongs to the NlpA lipoprotein family
KM406_RS01775	COG1846	Transcriptional regulator
KM406_RS01800	COG1597	lipid kinase activity
KM406_RS01805	COG0546	phosphoglycolate phosphatase activity
KM406_RS01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM406_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS01825	COG2076	Multidrug Resistance protein
KM406_RS01830	COG2309	aminopeptidase activity
KM406_RS01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM406_RS01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM406_RS01865	COG4807	Protein conserved in bacteria
KM406_RS01890	COG1757	Na H antiporter
KM406_RS01895	COG1473	amidohydrolase
KM406_RS01910	COG0450	alkyl hydroperoxide reductase
KM406_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS01940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM406_RS01955	COG0166	Belongs to the GPI family
KM406_RS01990	COG5002	protein histidine kinase activity
KM406_RS02010	COG3541	Predicted nucleotidyltransferase
KM406_RS02015	COG2814	Major facilitator Superfamily
KM406_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
KM406_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM406_RS02030	COG0765	amino acid transport
KM406_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM406_RS02045	COG0840	transmembrane signaling receptor activity
KM406_RS02050	COG0840	transmembrane signaling receptor activity
KM406_RS02055	COG0366	Alpha amylase catalytic
KM406_RS02060	COG1263	PTS System
KM406_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM406_RS02060	COG2190	(PTS) system
KM406_RS02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM406_RS02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM406_RS02115	COG1116	anion transmembrane transporter activity
KM406_RS02120	COG0488	(ABC) transporter
KM406_RS02165	COG2270	Major facilitator Superfamily
KM406_RS02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM406_RS02195	COG2310	stress, protein
KM406_RS02200	COG2310	stress, protein
KM406_RS02205	COG2310	stress, protein
KM406_RS02210	COG0861	Integral membrane protein TerC family
KM406_RS02220	COG3853	Toxic anion resistance protein (TelA)
KM406_RS02235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM406_RS02245	COG1295	ribonuclease BN
KM406_RS02250	COG2217	Heavy metal translocating P-type atpase
KM406_RS02255	COG0697	spore germination
KM406_RS02275	COG0586	Pfam SNARE associated Golgi protein
KM406_RS02290	COG3871	stress protein (general stress protein 26)
KM406_RS02295	COG0387	Pfam Sodium calcium exchanger
KM406_RS02305	COG0535	radical SAM domain protein
KM406_RS02330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM406_RS02335	COG0582	viral genome integration into host DNA
KM406_RS02345	COG1396	sequence-specific DNA binding
KM406_RS02360	COG1396	sequence-specific DNA binding
KM406_RS02395	COG1484	DNA-dependent DNA replication
KM406_RS02630	COG0101	tRNA pseudouridine synthase activity
KM406_RS02640	COG3829	transcription factor binding
KM406_RS02650	COG0833	amino acid
KM406_RS02655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM406_RS02685	COG1263	PTS System
KM406_RS02685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM406_RS02690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM406_RS02705	COG0463	Glycosyl transferase, family 2
KM406_RS02715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM406_RS02715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM406_RS02730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM406_RS02750	COG1228	amidohydrolase
KM406_RS02755	COG1090	epimerase
KM406_RS02785	COG1988	membrane-bound metal-dependent
KM406_RS02790	COG1194	a g-specific adenine glycosylase
KM406_RS02815	COG1132	(ABC) transporter
KM406_RS02820	COG4129	membrane
KM406_RS02825	COG0067	glutamate synthase
KM406_RS02825	COG0069	glutamate synthase activity
KM406_RS02825	COG0070	glutamate synthase
KM406_RS02835	COG4555	ABC transporter
KM406_RS02855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM406_RS02860	COG0735	belongs to the Fur family
KM406_RS02975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM406_RS02980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM406_RS02990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM406_RS03000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM406_RS03010	COG2766	serine protein kinase
KM406_RS03030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM406_RS03040	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM406_RS03045	COG2268	Band 7 protein
KM406_RS03055	COG3290	protein histidine kinase activity
KM406_RS03060	COG4565	transcriptional regulatory protein
KM406_RS03065	COG2851	Citrate transporter
KM406_RS03085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM406_RS03090	COG3842	ATPase activity
KM406_RS03095	COG1175	transmembrane transport
KM406_RS03100	COG0395	ABC-type sugar transport system, permease component
KM406_RS03110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM406_RS03115	COG0745	RESPONSE REGULATOR receiver
KM406_RS03120	COG5002	protein histidine kinase activity
KM406_RS03130	COG4990	cell redox homeostasis
KM406_RS03140	COG3290	protein histidine kinase activity
KM406_RS03145	COG4565	transcriptional regulatory protein
KM406_RS03150	COG3493	citrate carrier protein
KM406_RS03155	COG0281	malic enzyme
KM406_RS03170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS03180	COG5002	protein histidine kinase activity
KM406_RS03185	COG0745	RESPONSE REGULATOR receiver
KM406_RS03190	COG0454	-acetyltransferase
KM406_RS03190	COG0456	acetyltransferase
KM406_RS03195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM406_RS03200	COG3383	formate dehydrogenase (NAD+) activity
KM406_RS03220	COG0531	amino acid
KM406_RS03225	COG0640	Transcriptional regulator
KM406_RS03230	COG2217	Heavy metal translocating P-type atpase
KM406_RS03235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM406_RS03250	COG3227	Zinc metalloprotease (Elastase)
KM406_RS03270	COG2720	vancomycin resistance protein
KM406_RS03275	COG1316	TRANSCRIPTIONal
KM406_RS03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS03285	COG0346	lactoylglutathione lyase activity
KM406_RS03295	COG1027	Aspartate ammonia-lyase
KM406_RS03300	COG1620	l-lactate permease
KM406_RS03315	COG3104	oligopeptide transport
KM406_RS03320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM406_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS03330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS03340	COG2226	methyltransferase
KM406_RS03345	COG0156	8-amino-7-oxononanoate synthase activity
KM406_RS03360	COG4548	von Willebrand factor, type A
KM406_RS03365	COG0714	Associated with various cellular activities
KM406_RS03370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM406_RS03390	COG0531	amino acid
KM406_RS03395	COG2188	Transcriptional regulator
KM406_RS03400	COG1263	PTS System
KM406_RS03400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM406_RS03405	COG0366	Alpha amylase catalytic
KM406_RS03420	COG0697	spore germination
KM406_RS03430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM406_RS03435	COG1115	amino acid carrier protein
KM406_RS03440	COG1126	abc transporter atp-binding protein
KM406_RS03445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM406_RS03450	COG0765	amino acid transport
KM406_RS03455	COG0765	amino acid transport
KM406_RS03460	COG0833	amino acid
KM406_RS03485	COG2378	regulation of single-species biofilm formation
KM406_RS03490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM406_RS03495	COG5002	protein histidine kinase activity
KM406_RS03510	COG0659	secondary active sulfate transmembrane transporter activity
KM406_RS03525	COG0747	negative chemotaxis
KM406_RS03535	COG0601	transmembrane transport
KM406_RS03540	COG4608	Belongs to the ABC transporter superfamily
KM406_RS03550	COG2271	Major facilitator Superfamily
KM406_RS03555	COG1846	Transcriptional regulator
KM406_RS03565	COG1609	Transcriptional regulator
KM406_RS03570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM406_RS03585	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM406_RS03590	COG1879	ABC-type sugar transport system periplasmic component
KM406_RS03615	COG1063	alcohol dehydrogenase
KM406_RS03630	COG3568	Endonuclease Exonuclease Phosphatase
KM406_RS03655	COG1968	undecaprenyl-diphosphatase activity
KM406_RS03660	COG0840	transmembrane signaling receptor activity
KM406_RS03665	COG3584	3D domain protein
KM406_RS03665	COG1388	LysM domain
KM406_RS03670	COG1476	TRANSCRIPTIONal
KM406_RS03685	COG3104	oligopeptide transport
KM406_RS03690	COG1114	Component of the transport system for branched-chain amino acids
KM406_RS03705	COG1113	amino acid transport
KM406_RS03710	COG2252	PERMEase
KM406_RS03735	COG0569	domain protein
KM406_RS03735	COG0475	glutathione-regulated potassium exporter activity
KM406_RS03750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM406_RS03755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM406_RS03760	COG4990	cell redox homeostasis
KM406_RS03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM406_RS03780	COG0697	spore germination
KM406_RS03785	COG0531	amino acid
KM406_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM406_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM406_RS03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM406_RS03805	COG1918	ferrous iron import across plasma membrane
KM406_RS03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM406_RS03815	COG0573	inorganic phosphate transmembrane transporter activity
KM406_RS03820	COG0581	inorganic phosphate transmembrane transporter activity
KM406_RS03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM406_RS03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM406_RS03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM406_RS03975	COG1116	anion transmembrane transporter activity
KM406_RS03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM406_RS03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM406_RS03990	COG0352	thiamine-phosphate diphosphorylase activity
KM406_RS03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM406_RS04000	COG2104	thiamine diphosphate biosynthetic process
KM406_RS04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM406_RS04015	COG0351	phosphomethylpyrimidine kinase
KM406_RS04055	COG2205	protein histidine kinase activity
KM406_RS04060	COG2814	Major facilitator Superfamily
KM406_RS04065	COG1846	Transcriptional regulator
KM406_RS04080	COG2252	PERMEase
KM406_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM406_RS04105	COG1621	beta-fructofuranosidase activity
KM406_RS04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM406_RS04110	COG1263	PTS System
KM406_RS04115	COG1609	Transcriptional regulator
KM406_RS04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM406_RS04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM406_RS04165	COG0778	Nitroreductase
KM406_RS04170	COG2719	SpoVR family
KM406_RS04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM406_RS04200	COG1937	Protein conserved in bacteria
KM406_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM406_RS04205	COG0425	Belongs to the sulfur carrier protein TusA family
KM406_RS04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM406_RS04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS04215	COG0425	Belongs to the sulfur carrier protein TusA family
KM406_RS04230	COG2210	Belongs to the sulfur carrier protein TusA family
KM406_RS04235	COG0730	response to heat
KM406_RS04245	COG1316	TRANSCRIPTIONal
KM406_RS04250	COG0604	alcohol dehydrogenase
KM406_RS04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM406_RS04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM406_RS04270	COG3711	transcriptional antiterminator
KM406_RS04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM406_RS04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM406_RS04300	COG3584	3D domain protein
KM406_RS04300	COG1388	LysM domain
KM406_RS04305	COG0577	efflux transmembrane transporter activity
KM406_RS04310	COG1136	(ABC) transporter
KM406_RS04320	COG5522	Integral membrane protein (intg_mem_TP0381)
KM406_RS04335	COG1114	Component of the transport system for branched-chain amino acids
KM406_RS04340	COG3546	catalase activity
KM406_RS04375	COG0586	Pfam SNARE associated Golgi protein
KM406_RS04410	COG0531	amino acid
KM406_RS04415	COG0475	glutathione-regulated potassium exporter activity
KM406_RS04425	COG1737	Transcriptional regulator
KM406_RS04435	COG1263	PTS System
KM406_RS04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM406_RS04445	COG2259	Doxx family
KM406_RS04460	COG0697	spore germination
KM406_RS04465	COG1522	sequence-specific DNA binding
KM406_RS04480	COG2076	Multidrug Resistance protein
KM406_RS04485	COG1309	transcriptional regulator
KM406_RS04490	COG2814	Major facilitator Superfamily
KM406_RS04495	COG1733	regulation of RNA biosynthetic process
KM406_RS04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM406_RS04510	COG4533	DNA binding
KM406_RS04515	COG2211	Major facilitator Superfamily
KM406_RS04525	COG0693	protein deglycase activity
KM406_RS04530	COG0693	protein deglycase activity
KM406_RS04530	COG0753	catalase activity
KM406_RS04540	COG0531	amino acid
KM406_RS04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM406_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS04560	COG1132	(ABC) transporter
KM406_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM406_RS04575	COG0765	amino acid transport
KM406_RS04580	COG1126	abc transporter atp-binding protein
KM406_RS04595	COG0189	ligase activity
KM406_RS04625	COG0028	Belongs to the TPP enzyme family
KM406_RS04630	COG3527	Alpha-acetolactate decarboxylase
KM406_RS04645	COG0561	phosphatase activity
KM406_RS04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM406_RS04675	COG0659	secondary active sulfate transmembrane transporter activity
KM406_RS04695	COG0653	protein targeting
KM406_RS04700	COG2244	polysaccharide biosynthetic process
KM406_RS04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM406_RS04715	COG4196	transglutaminase domain protein
KM406_RS04730	COG1696	Membrane protein involved in D-alanine export
KM406_RS04745	COG1024	Enoyl-CoA hydratase
KM406_RS04765	COG1363	Peptidase, m42
KM406_RS04785	COG3938	Belongs to the proline racemase family
KM406_RS04825	COG0601	transmembrane transport
KM406_RS04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM406_RS04840	COG4608	Belongs to the ABC transporter superfamily
KM406_RS04875	COG0477	Major facilitator Superfamily
KM406_RS04880	COG3290	protein histidine kinase activity
KM406_RS04885	COG4565	transcriptional regulatory protein
KM406_RS04890	COG3181	Tripartite tricarboxylate transporter family receptor
KM406_RS04920	COG0789	Transcriptional regulator
KM406_RS04920	COG4978	Transcriptional regulator
KM406_RS04935	COG0305	Participates in initiation and elongation during chromosome replication
KM406_RS04975	COG0477	Major facilitator Superfamily
KM406_RS05020	COG3320	Male sterility
KM406_RS05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM406_RS05025	COG1309	transcriptional regulator
KM406_RS05045	COG1183	phosphatidylcholine synthase activity
KM406_RS05065	COG2376	Dihydroxyacetone kinase
KM406_RS05075	COG2376	Dihydroxyacetone kinase
KM406_RS05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM406_RS05085	COG1959	2 iron, 2 sulfur cluster binding
KM406_RS05115	COG2770	Histidine kinase
KM406_RS05115	COG3437	response regulator, receiver
KM406_RS05165	COG3237	CsbD-like
KM406_RS05190	COG1191	sigma factor activity
KM406_RS05200	COG2208	phosphoserine phosphatase activity
KM406_RS05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM406_RS05210	COG2205	protein histidine kinase activity
KM406_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM406_RS05210	COG2198	Histidine kinase
KM406_RS05210	COG0784	Response regulator, receiver
KM406_RS05265	COG0420	3'-5' exonuclease activity
KM406_RS05290	COG1309	transcriptional regulator
KM406_RS05295	COG2814	Major facilitator Superfamily
KM406_RS05300	COG0346	lactoylglutathione lyase activity
KM406_RS05310	COG0457	Tetratricopeptide repeat
KM406_RS05315	COG2267	carboxylic ester hydrolase activity
KM406_RS05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM406_RS05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM406_RS05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM406_RS05390	COG0477	Major facilitator Superfamily
KM406_RS05395	COG0477	Major facilitator Superfamily
KM406_RS05405	COG3973	AAA domain
KM406_RS05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM406_RS05430	COG4980	gas vesicle protein
KM406_RS05435	COG0537	adenosine 5'-monophosphoramidase activity
KM406_RS05440	COG1131	(ABC) transporter
KM406_RS05445	COG4473	ABC transporter
KM406_RS05460	COG1309	transcriptional regulator
KM406_RS05470	COG3402	PFAM membrane-flanked domain
KM406_RS05515	COG3402	PFAM membrane-flanked domain
KM406_RS05520	COG3428	Bacterial PH domain
KM406_RS05525	COG2329	Antibiotic biosynthesis monooxygenase
KM406_RS05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM406_RS05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM406_RS05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM406_RS05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM406_RS05580	COG1309	transcriptional regulator
KM406_RS05585	COG1511	domain protein
KM406_RS05610	COG1609	Transcriptional regulator
KM406_RS05620	COG1234	tRNA 3'-trailer cleavage
KM406_RS05625	COG0095	Lipoate-protein ligase
KM406_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
KM406_RS05665	COG3209	COG3209 Rhs family protein
KM406_RS05705	COG1078	dGTPase activity
KM406_RS05715	COG1595	DNA-templated transcription, initiation
KM406_RS05720	COG2207	Transcriptional regulator
KM406_RS05720	COG3708	Transcriptional regulator
KM406_RS05735	COG2205	protein histidine kinase activity
KM406_RS05740	COG0745	RESPONSE REGULATOR receiver
KM406_RS05765	COG0501	Belongs to the peptidase M48B family
KM406_RS05770	COG0840	transmembrane signaling receptor activity
KM406_RS05775	COG0697	spore germination
KM406_RS05795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM406_RS05800	COG2224	Isocitrate lyase
KM406_RS05825	COG4903	ComK protein
KM406_RS05830	COG0398	Pfam SNARE associated Golgi protein
KM406_RS05840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM406_RS05845	COG1074	ATP-dependent DNA helicase activity
KM406_RS05890	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM406_RS05915	COG0367	asparagine synthase
KM406_RS05920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM406_RS05925	COG0753	catalase activity
KM406_RS05930	COG0004	ammonium transporteR
KM406_RS05950	COG2996	Protein conserved in bacteria
KM406_RS05960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM406_RS05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS05985	COG0561	phosphatase activity
KM406_RS05995	COG0542	response to heat
KM406_RS06005	COG2267	carboxylic ester hydrolase activity
KM406_RS06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM406_RS06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM406_RS06030	COG5504	Zn-dependent protease
KM406_RS06040	COG0180	Tryptophanyl-tRNA synthetase
KM406_RS06050	COG4166	transmembrane transport
KM406_RS06055	COG0601	transmembrane transport
KM406_RS06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM406_RS06065	COG0444	Belongs to the ABC transporter superfamily
KM406_RS06070	COG4608	Belongs to the ABC transporter superfamily
KM406_RS06075	COG0534	Mate efflux family protein
KM406_RS06080	COG4166	transmembrane transport
KM406_RS06095	COG0861	Integral membrane protein TerC family
KM406_RS06100	COG4862	establishment of competence for transformation
KM406_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM406_RS06115	COG1164	Oligoendopeptidase f
KM406_RS06125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM406_RS06130	COG2346	COG2346, Truncated hemoglobins
KM406_RS06135	COG4116	CYTH
KM406_RS06145	COG2357	RelA SpoT domain protein
KM406_RS06155	COG0564	pseudouridine synthase activity
KM406_RS06175	COG0463	Glycosyl transferase, family 2
KM406_RS06175	COG1216	Glycosyl transferase, family 2
KM406_RS06195	COG0457	Tetratricopeptide repeat
KM406_RS06195	COG0463	Glycosyl transferase, family 2
KM406_RS06215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM406_RS06230	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM406_RS06275	COG2153	protein acetylation
KM406_RS06285	COG2382	esterase
KM406_RS06300	COG5492	domain, Protein
KM406_RS06305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM406_RS06315	COG0512	Glutamine amidotransferase of anthranilate synthase
KM406_RS06315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM406_RS06350	COG1620	l-lactate permease
KM406_RS06355	COG5634	Uncharacterized conserved protein (DUF2278)
KM406_RS06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM406_RS06420	COG1476	TRANSCRIPTIONal
KM406_RS06480	COG2226	methyltransferase
KM406_RS06490	COG1686	Belongs to the peptidase S11 family
KM406_RS06495	COG0681	Belongs to the peptidase S26 family
KM406_RS06530	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS06535	COG3842	ATPase activity
KM406_RS06540	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM406_RS06545	COG1177	transmembrane transport
KM406_RS06550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM406_RS06560	COG2409	Drug exporters of the RND superfamily
KM406_RS06570	COG0564	pseudouridine synthase activity
KM406_RS06580	COG2340	Cysteine-rich secretory protein family
KM406_RS06585	COG0247	lactate metabolic process
KM406_RS06590	COG0277	FAD linked oxidase domain protein
KM406_RS06595	COG3835	regulator
KM406_RS06605	COG0745	RESPONSE REGULATOR receiver
KM406_RS06610	COG5002	protein histidine kinase activity
KM406_RS06615	COG2186	Transcriptional regulator
KM406_RS06635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM406_RS06645	COG2116	formate transmembrane transporter activity
KM406_RS06650	COG0861	Integral membrane protein TerC family
KM406_RS06655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM406_RS06665	COG2030	dehydratase
KM406_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS06690	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM406_RS06695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM406_RS06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM406_RS06715	COG1840	ABC-type Fe3 transport system, periplasmic component
KM406_RS06745	COG1349	DNA-binding transcription factor activity
KM406_RS06765	COG2861	carbohydrate metabolic process
KM406_RS06775	COG3852	Histidine kinase
KM406_RS06780	COG1846	Transcriptional regulator
KM406_RS06790	COG2318	DinB family
KM406_RS06800	COG5002	protein histidine kinase activity
KM406_RS06810	COG0720	synthase
KM406_RS06825	COG4873	Protein conserved in bacteria
KM406_RS06855	COG1780	Probably involved in ribonucleotide reductase function
KM406_RS06875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM406_RS06880	COG1725	Transcriptional regulator
KM406_RS06885	COG1131	(ABC) transporter
KM406_RS06895	COG1131	(ABC) transporter
KM406_RS06900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM406_RS06915	COG1522	sequence-specific DNA binding
KM406_RS06925	COG1335	isochorismatase
KM406_RS06935	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM406_RS06940	COG2070	2-Nitropropane dioxygenase
KM406_RS06945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM406_RS06955	COG1696	Membrane protein involved in D-alanine export
KM406_RS06980	COG0716	FMN binding
KM406_RS06995	COG3173	Aminoglycoside phosphotransferase
KM406_RS07015	COG0534	Mate efflux family protein
KM406_RS07020	COG1968	undecaprenyl-diphosphatase activity
KM406_RS07035	COG1846	Transcriptional regulator
KM406_RS07045	COG1301	dicarboxylic acid transport
KM406_RS07050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM406_RS07055	COG4709	membrane
KM406_RS07060	COG3874	Sporulation protein YtfJ
KM406_RS07085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM406_RS07090	COG0028	Belongs to the TPP enzyme family
KM406_RS07095	COG0440	acetolactate synthase activity
KM406_RS07100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM406_RS07110	COG0473	3-isopropylmalate dehydrogenase activity
KM406_RS07135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM406_RS07170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM406_RS07185	COG1183	phosphatidylcholine synthase activity
KM406_RS07190	COG1368	sulfuric ester hydrolase activity
KM406_RS07200	COG0019	diaminopimelate decarboxylase activity
KM406_RS07220	COG0529	Catalyzes the synthesis of activated sulfate
KM406_RS07225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM406_RS07245	COG1648	precorrin-2 dehydrogenase activity
KM406_RS07250	COG0733	neurotransmitter:sodium symporter activity
KM406_RS07270	COG1757	Na H antiporter
KM406_RS07285	COG4758	membrane
KM406_RS07290	COG4585	Histidine kinase
KM406_RS07295	COG2197	response regulator
KM406_RS07305	COG1114	Component of the transport system for branched-chain amino acids
KM406_RS07315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM406_RS07340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM406_RS07340	COG1017	nitric oxide dioxygenase activity
KM406_RS07355	COG0730	response to heat
KM406_RS07360	COG0306	phosphate transporter
KM406_RS07365	COG1392	Phosphate transport regulator
KM406_RS07370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM406_RS07385	COG3852	Histidine kinase
KM406_RS07390	COG1801	Protein of unknown function DUF72
KM406_RS07400	COG0582	viral genome integration into host DNA
KM406_RS07405	COG5002	protein histidine kinase activity
KM406_RS07425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM406_RS07425	COG0392	lysyltransferase activity
KM406_RS07440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM406_RS07445	COG1686	Belongs to the peptidase S11 family
KM406_RS07450	COG2715	membrane protein required for spore maturation
KM406_RS07455	COG0700	Nucleoside recognition
KM406_RS07460	COG1187	pseudouridine synthase activity
KM406_RS07470	COG1333	cytochrome c biogenesis protein
KM406_RS07475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM406_RS07480	COG0745	RESPONSE REGULATOR receiver
KM406_RS07485	COG5002	protein histidine kinase activity
KM406_RS07490	COG2096	Adenosyltransferase
KM406_RS07505	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM406_RS07510	COG1141	Ferredoxin
KM406_RS07515	COG4955	Helix-turn-helix domain
KM406_RS07520	COG0514	ATP-dependent DNA helicase (RecQ)
KM406_RS07525	COG1266	CAAX protease self-immunity
KM406_RS07545	COG4862	establishment of competence for transformation
KM406_RS07550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM406_RS07570	COG0492	ferredoxin-NADP+ reductase activity
KM406_RS07575	COG0252	asparaginase activity
KM406_RS07645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM406_RS07660	COG0142	geranyltranstransferase activity
KM406_RS07670	COG0142	geranyltranstransferase activity
KM406_RS07690	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM406_RS07695	COG0457	Tetratricopeptide repeat
KM406_RS07715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM406_RS07725	COG4347	Protein of unknown function (DUF1405)
KM406_RS07740	COG2738	Putative neutral zinc metallopeptidase
KM406_RS07750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS07755	COG1694	Mazg nucleotide pyrophosphohydrolase
KM406_RS07770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM406_RS07775	COG0438	transferase activity, transferring glycosyl groups
KM406_RS07830	COG3935	DnaD domain protein
KM406_RS07835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM406_RS07905	COG0116	Belongs to the methyltransferase superfamily
KM406_RS07915	COG1199	ATP-dependent helicase activity
KM406_RS07920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM406_RS07930	COG3173	Aminoglycoside phosphotransferase
KM406_RS07935	COG0024	Methionine aminopeptidase
KM406_RS07945	COG2233	PERMEase
KM406_RS07950	COG2311	Membrane
KM406_RS07955	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM406_RS07965	COG0456	acetyltransferase
KM406_RS08015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM406_RS08040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM406_RS08055	COG1215	transferase activity, transferring glycosyl groups
KM406_RS08060	COG0438	transferase activity, transferring glycosyl groups
KM406_RS08075	COG0454	-acetyltransferase
KM406_RS08095	COG0328	RNA-DNA hybrid ribonuclease activity
KM406_RS08135	COG1280	lysine exporter protein (LysE YggA)
KM406_RS08150	COG3162	membrane
KM406_RS08155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM406_RS08160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM406_RS08170	COG0475	glutathione-regulated potassium exporter activity
KM406_RS08175	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM406_RS08180	COG0789	Transcriptional regulator
KM406_RS08180	COG4978	Transcriptional regulator
KM406_RS08190	COG2323	membrane
KM406_RS08195	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM406_RS08250	COG1923	regulation of RNA biosynthetic process
KM406_RS08260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM406_RS08265	COG1360	Flagellar Motor Protein
KM406_RS08270	COG2201	protein-glutamate methylesterase activity
KM406_RS08280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM406_RS08280	COG1776	CheC inhibitor of MCP methylation
KM406_RS08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM406_RS08315	COG1256	bacterial-type flagellum assembly
KM406_RS08340	COG1815	bacterial-type flagellum-dependent cell motility
KM406_RS08345	COG1558	bacterial-type flagellum-dependent cell motility
KM406_RS08360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM406_RS08370	COG1157	protein secretion by the type III secretion system
KM406_RS08405	COG0784	Response regulator, receiver
KM406_RS08405	COG0835	chemotaxis
KM406_RS08415	COG0463	Glycosyl transferase, family 2
KM406_RS08440	COG0463	Glycosyl transferase, family 2
KM406_RS08440	COG0457	Tetratricopeptide repeat
KM406_RS08455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM406_RS08460	COG0741	lytic transglycosylase activity
KM406_RS08475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM406_RS08475	COG1776	CheC inhibitor of MCP methylation
KM406_RS08485	COG1338	Plays a role in the flagellum-specific transport system
KM406_RS08490	COG1987	bacterial-type flagellum assembly
KM406_RS08500	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM406_RS08505	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM406_RS08510	COG1419	protein localization to endoplasmic reticulum
KM406_RS08515	COG4786	Flagellar basal body rod
KM406_RS08520	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM406_RS08545	COG1309	transcriptional regulator
KM406_RS08565	COG2329	Antibiotic biosynthesis monooxygenase
KM406_RS08590	COG0583	DNA-binding transcription factor activity
KM406_RS08600	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM406_RS08610	COG1234	tRNA 3'-trailer cleavage
KM406_RS08635	COG1686	Belongs to the peptidase S11 family
KM406_RS08645	COG0406	alpha-ribazole phosphatase activity
KM406_RS08675	COG0367	asparagine synthase
KM406_RS08705	COG1802	Transcriptional regulator
KM406_RS08710	COG0697	spore germination
KM406_RS08715	COG0523	cobalamin synthesis protein
KM406_RS08720	COG0701	Predicted permease
KM406_RS08730	COG0438	transferase activity, transferring glycosyl groups
KM406_RS08730	COG1216	Glycosyl transferase, family 2
KM406_RS08735	COG1757	Na H antiporter
KM406_RS08740	COG0114	fumarate hydratase activity
KM406_RS08765	COG3340	Belongs to the peptidase S51 family
KM406_RS08785	COG0785	Cytochrome C biogenesis protein
KM406_RS08815	COG2733	membrane
KM406_RS08850	COG1131	(ABC) transporter
KM406_RS08865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM406_RS08870	COG0528	UMP kinase activity
KM406_RS08880	COG1027	Aspartate ammonia-lyase
KM406_RS08885	COG0281	malic enzyme
KM406_RS08890	COG4191	Histidine kinase
KM406_RS08895	COG0784	Response regulator, receiver
KM406_RS08900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM406_RS08960	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM406_RS08970	COG2814	Major facilitator Superfamily
KM406_RS08985	COG1966	Carbon starvation protein
KM406_RS09000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM406_RS09010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM406_RS09020	COG2223	nitrite transmembrane transporter activity
KM406_RS09025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM406_RS09040	COG2244	polysaccharide biosynthetic process
KM406_RS09045	COG0733	neurotransmitter:sodium symporter activity
KM406_RS09055	COG5566	PFAM Mor transcription activator
KM406_RS09060	COG2323	membrane
KM406_RS09080	COG2084	Dehydrogenase
KM406_RS09095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM406_RS09105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM406_RS09110	COG0028	Belongs to the TPP enzyme family
KM406_RS09115	COG0440	acetolactate synthase activity
KM406_RS09120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM406_RS09130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM406_RS09155	COG2814	Major facilitator Superfamily
KM406_RS09160	COG3384	dioxygenase
KM406_RS09170	COG3279	Response regulator of the LytR AlgR family
KM406_RS09175	COG0427	acetyl-CoA hydrolase
KM406_RS09195	COG1073	alpha beta
KM406_RS09225	COG0535	radical SAM domain protein
KM406_RS09230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS09250	COG1914	H( )-stimulated, divalent metal cation uptake system
KM406_RS09265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM406_RS09295	COG2390	Transcriptional regulator
KM406_RS09305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS09310	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM406_RS09325	COG4224	UPF0291 protein
KM406_RS09345	COG0006	proline dipeptidase activity
KM406_RS09350	COG2132	Multicopper oxidase
KM406_RS09365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM406_RS09380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM406_RS09395	COG1276	copper resistance
KM406_RS09395	COG2372	response to copper ion
KM406_RS09400	COG4549	nuclear export factor GLE1
KM406_RS09410	COG0697	spore germination
KM406_RS09415	COG0583	DNA-binding transcription factor activity
KM406_RS09420	COG1959	2 iron, 2 sulfur cluster binding
KM406_RS09425	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM406_RS09430	COG0778	Nitroreductase
KM406_RS09440	COG0628	permease
KM406_RS09450	COG1231	oxidoreductase activity
KM406_RS09455	COG0523	cobalamin synthesis protein
KM406_RS09470	COG0318	PFAM AMP-dependent synthetase and ligase
KM406_RS09475	COG2030	dehydratase
KM406_RS09480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM406_RS09490	COG0411	ABC transporter
KM406_RS09510	COG0583	DNA-binding transcription factor activity
KM406_RS09520	COG1942	4-Oxalocrotonate Tautomerase
KM406_RS09530	COG1846	Transcriptional regulator
KM406_RS09540	COG1271	oxidase subunit
KM406_RS09545	COG1294	oxidase, subunit
KM406_RS09550	COG4988	ABC transporter
KM406_RS09555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM406_RS09575	COG1686	Belongs to the peptidase S11 family
KM406_RS09590	COG1388	LysM domain
KM406_RS09590	COG0791	NLP P60 protein
KM406_RS09605	COG0745	RESPONSE REGULATOR receiver
KM406_RS09610	COG5002	protein histidine kinase activity
KM406_RS09620	COG0300	oxidoreductase activity
KM406_RS09655	COG0460	homoserine dehydrogenase
KM406_RS09680	COG1316	TRANSCRIPTIONal
KM406_RS09690	COG0745	RESPONSE REGULATOR receiver
KM406_RS09695	COG5002	protein histidine kinase activity
KM406_RS09710	COG1285	pathogenesis
KM406_RS09715	COG1247	-acetyltransferase
KM406_RS09735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM406_RS09745	COG1082	Xylose isomerase domain protein TIM barrel
KM406_RS09760	COG1279	arginine transmembrane transporter activity
KM406_RS09770	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM406_RS09810	COG2002	toxin-antitoxin pair type II binding
KM406_RS09815	COG1404	Belongs to the peptidase S8 family
KM406_RS09820	COG0640	Transcriptional regulator
KM406_RS09825	COG0667	Aldo Keto reductase
KM406_RS09830	COG2814	Major facilitator Superfamily
KM406_RS09855	COG0840	transmembrane signaling receptor activity
KM406_RS09870	COG3949	Membrane
KM406_RS09875	COG0783	Belongs to the Dps family
KM406_RS09890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM406_RS09900	COG1231	oxidoreductase activity
KM406_RS09910	COG4989	oxidoreductase activity
KM406_RS09915	COG0523	cobalamin synthesis protein
KM406_RS09920	COG0456	acetyltransferase
KM406_RS09980	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM406_RS09980	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM406_RS09990	COG0702	epimerase
KM406_RS10000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM406_RS10010	COG4166	transmembrane transport
KM406_RS10025	COG0406	alpha-ribazole phosphatase activity
KM406_RS10035	COG5337	Spore coat protein CotH
KM406_RS10040	COG1051	belongs to the nudix hydrolase family
KM406_RS10045	COG0586	Pfam SNARE associated Golgi protein
KM406_RS10050	COG2244	polysaccharide biosynthetic process
KM406_RS10060	COG0701	Predicted permease
KM406_RS10065	COG3689	TIGRFAM TIGR03943 family protein
KM406_RS10070	COG1607	acyl-coa hydrolase
KM406_RS10080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM406_RS10095	COG0702	epimerase
KM406_RS10100	COG2839	Protein conserved in bacteria
KM406_RS10105	COG1253	flavin adenine dinucleotide binding
KM406_RS10120	COG1114	Component of the transport system for branched-chain amino acids
KM406_RS10125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM406_RS10145	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM406_RS10155	COG1876	peptidase activity
KM406_RS10165	COG0154	amidase activity
KM406_RS10170	COG2211	Major facilitator Superfamily
KM406_RS10190	COG0561	phosphatase activity
KM406_RS10200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM406_RS10205	COG4106	trans-aconitate 2-methyltransferase activity
KM406_RS10220	COG1819	glycosyl
KM406_RS10225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS10230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS10265	COG0456	acetyltransferase
KM406_RS10320	COG3874	Sporulation protein YtfJ
KM406_RS10345	COG2226	methyltransferase
KM406_RS10370	COG0346	lactoylglutathione lyase activity
KM406_RS10380	COG0604	alcohol dehydrogenase
KM406_RS10385	COG1595	DNA-templated transcription, initiation
KM406_RS10410	COG0386	Belongs to the glutathione peroxidase family
KM406_RS10415	COG1305	Transglutaminase-like
KM406_RS10420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM406_RS10425	COG0714	Associated with various cellular activities
KM406_RS10440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM406_RS10445	COG1140	nitrate reductase beta subunit
KM406_RS10450	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM406_RS10455	COG2181	nitrate reductase activity
KM406_RS10475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM406_RS10480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM406_RS10485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM406_RS10490	COG0303	'Molybdopterin
KM406_RS10495	COG0314	molybdopterin synthase activity
KM406_RS10505	COG2223	nitrite transmembrane transporter activity
KM406_RS10520	COG1648	precorrin-2 dehydrogenase activity
KM406_RS10530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM406_RS10530	COG1587	Uroporphyrinogen-III synthase
KM406_RS10535	COG2146	nitrite reductase [NAD(P)H] activity
KM406_RS10540	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM406_RS10545	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM406_RS10580	COG2359	stage V sporulation protein S
KM406_RS10605	COG1418	mRNA catabolic process
KM406_RS10610	COG0488	(ABC) transporter
KM406_RS10625	COG0629	single-stranded DNA binding
KM406_RS10640	COG1413	lyase activity
KM406_RS10655	COG2521	methyltransferase
KM406_RS10655	COG2136	Putative SAM-dependent methyltransferase
KM406_RS10660	COG0018	arginyl-trna synthetase
KM406_RS10685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM406_RS10705	COG0017	Asparaginyl-tRNA synthetase
KM406_RS10725	COG1674	ftsk spoiiie
KM406_RS10795	COG1929	Belongs to the glycerate kinase type-1 family
KM406_RS10800	COG0471	metal ion transport
KM406_RS10805	COG0745	RESPONSE REGULATOR receiver
KM406_RS10810	COG5002	protein histidine kinase activity
KM406_RS10810	COG3850	Histidine kinase
KM406_RS10825	COG0733	neurotransmitter:sodium symporter activity
KM406_RS10850	COG2610	gluconate transmembrane transporter activity
KM406_RS10855	COG1454	alcohol dehydrogenase
KM406_RS10860	COG1794	racemase activity, acting on amino acids and derivatives
KM406_RS10870	COG0456	acetyltransferase
KM406_RS10885	COG1131	(ABC) transporter
KM406_RS10900	COG0546	phosphoglycolate phosphatase activity
KM406_RS10920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM406_RS10935	COG0768	penicillin binding
KM406_RS10940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM406_RS10945	COG0204	Acyl-transferase
KM406_RS10950	COG1272	protein, Hemolysin III
KM406_RS10960	COG0805	protein transport
KM406_RS10970	COG1307	EDD domain protein, DegV family
KM406_RS10975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM406_RS10980	COG1999	signal sequence binding
KM406_RS10985	COG0071	Belongs to the small heat shock protein (HSP20) family
KM406_RS10990	COG0367	asparagine synthase
KM406_RS11005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM406_RS11010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM406_RS11045	COG0668	transmembrane transport
KM406_RS11050	COG4585	Histidine kinase
KM406_RS11050	COG2203	Gaf domain
KM406_RS11055	COG2197	response regulator
KM406_RS11065	COG1064	alcohol dehydrogenase
KM406_RS11120	COG0517	IMP dehydrogenase activity
KM406_RS11120	COG1125	glycine betaine transport
KM406_RS11125	COG1174	glycine betaine transport
KM406_RS11160	COG1253	flavin adenine dinucleotide binding
KM406_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS11170	COG5506	Protein of unknown function (DUF1694)
KM406_RS11185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM406_RS11190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM406_RS11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM406_RS11205	COG0456	acetyltransferase
KM406_RS11210	COG3829	transcription factor binding
KM406_RS11215	COG1509	lysine 2,3-aminomutase activity
KM406_RS11255	COG4326	sporulation control protein
KM406_RS11260	COG0671	phosphoesterase, PA-phosphatase related
KM406_RS11265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM406_RS11270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM406_RS11300	COG1715	Restriction endonuclease
KM406_RS11300	COG1787	Restriction endonuclease
KM406_RS11390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM406_RS11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM406_RS11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM406_RS11440	COG2814	Major facilitator Superfamily
KM406_RS11445	COG4841	protein insertion into membrane
KM406_RS11450	COG0372	Belongs to the citrate synthase family
KM406_RS11455	COG2079	MmgE PrpD family protein
KM406_RS11460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM406_RS11465	COG1960	acyl-CoA dehydrogenase activity
KM406_RS11470	COG2084	Dehydrogenase
KM406_RS11480	COG1280	lysine exporter protein (LysE YggA)
KM406_RS11485	COG1024	Enoyl-CoA hydratase
KM406_RS11500	COG0420	3'-5' exonuclease activity
KM406_RS11505	COG0419	ATPase involved in DNA repair
KM406_RS11525	COG2223	nitrite transmembrane transporter activity
KM406_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS11535	COG1169	isochorismate synthase
KM406_RS11540	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM406_RS11545	COG1535	isochorismatase
KM406_RS11545	COG3433	isochorismatase activity
KM406_RS11550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM406_RS11555	COG3251	PFAM MbtH domain protein
KM406_RS11560	COG2814	Major facilitator Superfamily
KM406_RS11575	COG0776	regulation of translation
KM406_RS11585	COG2318	DinB family
KM406_RS11595	COG1115	amino acid carrier protein
KM406_RS11610	COG2329	Antibiotic biosynthesis monooxygenase
KM406_RS11615	COG1187	pseudouridine synthase activity
KM406_RS11620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM406_RS11635	COG0596	Alpha beta hydrolase
KM406_RS11640	COG2814	Major facilitator Superfamily
KM406_RS11660	COG2226	methyltransferase
KM406_RS11705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS11740	COG1247	-acetyltransferase
KM406_RS11770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM406_RS11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS11790	COG1278	Cold shock
KM406_RS11805	COG0010	Belongs to the arginase family
KM406_RS11810	COG0561	phosphatase activity
KM406_RS11855	COG0583	DNA-binding transcription factor activity
KM406_RS11860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM406_RS11875	COG0583	DNA-binding transcription factor activity
KM406_RS11880	COG2258	MOSC domain
KM406_RS11895	COG1132	(ABC) transporter
KM406_RS11900	COG1132	(ABC) transporter
KM406_RS11920	COG1396	sequence-specific DNA binding
KM406_RS11945	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM406_RS11950	COG1595	DNA-templated transcription, initiation
KM406_RS11975	COG1649	PFAM Uncharacterised BCR, COG1649
KM406_RS12000	COG2971	BadF BadG BcrA BcrD
KM406_RS12005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM406_RS12010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM406_RS12030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS12060	COG1309	transcriptional regulator
KM406_RS12075	COG0577	efflux transmembrane transporter activity
KM406_RS12075	COG1136	(ABC) transporter
KM406_RS12080	COG3615	Tellurite resistance protein tehB
KM406_RS12080	COG0500	methyltransferase
KM406_RS12090	COG2226	methyltransferase
KM406_RS12095	COG3961	Belongs to the TPP enzyme family
KM406_RS12100	COG1846	Transcriptional regulator
KM406_RS12140	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM406_RS12155	COG1595	DNA-templated transcription, initiation
KM406_RS12165	COG0768	penicillin binding
KM406_RS12175	COG2367	Beta-lactamase
KM406_RS12180	COG0671	phosphoesterase, PA-phosphatase related
KM406_RS12185	COG1609	Transcriptional regulator
KM406_RS12190	COG2814	Major facilitator Superfamily
KM406_RS12195	COG0673	inositol 2-dehydrogenase activity
KM406_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS12220	COG0191	fructose-bisphosphate aldolase activity
KM406_RS12225	COG3718	enzyme involved in inositol metabolism
KM406_RS12250	COG0457	Tetratricopeptide repeat
KM406_RS12255	COG1476	TRANSCRIPTIONal
KM406_RS12270	COG1876	peptidase activity
KM406_RS12290	COG1309	transcriptional regulator
KM406_RS12295	COG0488	(ABC) transporter
KM406_RS12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS12325	COG1252	NADH dehydrogenase
KM406_RS12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM406_RS12345	COG1131	(ABC) transporter
KM406_RS12355	COG1309	transcriptional regulator
KM406_RS12370	COG1960	acyl-CoA dehydrogenase activity
KM406_RS12375	COG0439	Biotin carboxylase
KM406_RS12380	COG0511	ligase activity, forming carbon-carbon bonds
KM406_RS12385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM406_RS12390	COG1024	Enoyl-CoA hydratase
KM406_RS12395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM406_RS12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM406_RS12410	COG1247	-acetyltransferase
KM406_RS12415	COG0572	uridine kinase
KM406_RS12425	COG2318	DinB family
KM406_RS12430	COG1686	Belongs to the peptidase S11 family
KM406_RS12455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM406_RS12495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM406_RS12495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM406_RS12520	COG2814	Major facilitator Superfamily
KM406_RS12540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM406_RS12560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS12575	COG1063	alcohol dehydrogenase
KM406_RS12590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM406_RS12595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM406_RS12610	COG3773	Cell wall hydrolase
KM406_RS12620	COG0745	RESPONSE REGULATOR receiver
KM406_RS12635	COG0488	(ABC) transporter
KM406_RS12650	COG1136	(ABC) transporter
KM406_RS12675	COG0460	homoserine dehydrogenase
KM406_RS12680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS12690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM406_RS12755	COG2124	cytochrome p450
KM406_RS12790	COG0561	phosphatase activity
KM406_RS12800	COG0768	penicillin binding
KM406_RS12805	COG1819	glycosyl
KM406_RS12810	COG1794	racemase activity, acting on amino acids and derivatives
KM406_RS12820	COG1122	ATPase activity
KM406_RS12835	COG2205	protein histidine kinase activity
KM406_RS12845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM406_RS12850	COG0604	alcohol dehydrogenase
KM406_RS12855	COG0768	penicillin binding
KM406_RS12865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM406_RS12900	COG0693	protein deglycase activity
KM406_RS12930	COG2814	Major facilitator Superfamily
KM406_RS12945	COG0584	glycerophosphoryl diester phosphodiesterase
KM406_RS12965	COG0697	spore germination
KM406_RS12995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM406_RS13005	COG2223	nitrite transmembrane transporter activity
KM406_RS13020	COG2816	NAD+ diphosphatase activity
KM406_RS13025	COG0592	DNA-directed DNA polymerase activity
KM406_RS13030	COG1051	belongs to the nudix hydrolase family
KM406_RS13065	COG3878	Protein conserved in bacteria
KM406_RS13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM406_RS13130	COG0322	excinuclease ABC activity
KM406_RS13170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM406_RS13195	COG1011	Hydrolase
KM406_RS13215	COG0076	glutamate decarboxylase activity
KM406_RS13230	COG1523	belongs to the glycosyl hydrolase 13 family
KM406_RS13235	COG3227	Zinc metalloprotease (Elastase)
KM406_RS13255	COG0201	protein transport
KM406_RS13265	COG0697	spore germination
KM406_RS13270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS13300	COG4129	membrane
KM406_RS13305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS13320	COG2959	enzyme of heme biosynthesis
KM406_RS13340	COG3483	tryptophan 2,3-dioxygenase activity
KM406_RS13345	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM406_RS13350	COG3844	kynureninase activity
KM406_RS13355	COG1309	transcriptional regulator
KM406_RS13385	COG3284	Transcriptional regulator
KM406_RS13405	COG1349	DNA-binding transcription factor activity
KM406_RS13425	COG1959	2 iron, 2 sulfur cluster binding
KM406_RS13440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM406_RS13445	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM406_RS13450	COG0022	dehydrogenase e1 component
KM406_RS13455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM406_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS13470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM406_RS13470	COG0456	acetyltransferase
KM406_RS13500	COG4176	ABC-type proline glycine betaine transport system permease component
KM406_RS13505	COG0517	IMP dehydrogenase activity
KM406_RS13505	COG4175	Glycine betaine
KM406_RS13530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM406_RS13535	COG2153	protein acetylation
KM406_RS13540	COG3397	chitin binding
KM406_RS13555	COG2205	protein histidine kinase activity
KM406_RS13580	COG0658	competence protein
KM406_RS13580	COG2333	competence protein COMEC
KM406_RS13630	COG3973	AAA domain
KM406_RS13645	COG2105	PFAM AIG2 family protein
KM406_RS13650	COG0514	ATP-dependent DNA helicase (RecQ)
KM406_RS13670	COG4637	Psort location Cytoplasmic, score
KM406_RS13695	COG3397	chitin binding
KM406_RS13710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM406_RS13715	COG1115	amino acid carrier protein
KM406_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS13725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM406_RS13735	COG3938	Belongs to the proline racemase family
KM406_RS13740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM406_RS13780	COG0586	Pfam SNARE associated Golgi protein
KM406_RS13795	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM406_RS13800	COG0519	Catalyzes the synthesis of GMP from XMP
KM406_RS13805	COG4166	transmembrane transport
KM406_RS13815	COG4948	Mandelate Racemase Muconate Lactonizing
KM406_RS13860	COG2936	dipeptidyl-peptidase activity
KM406_RS13865	COG5002	protein histidine kinase activity
KM406_RS13915	COG1307	EDD domain protein, DegV family
KM406_RS13935	COG2814	Major facilitator Superfamily
KM406_RS13945	COG1664	Polymer-forming cytoskeletal
KM406_RS13950	COG0789	Transcriptional regulator
KM406_RS13955	COG4533	DNA binding
KM406_RS13960	COG2814	Major facilitator Superfamily
KM406_RS13960	COG0477	Major facilitator Superfamily
KM406_RS13980	COG2261	transglycosylase associated protein
KM406_RS13995	COG2226	methyltransferase
KM406_RS14030	COG0436	Aminotransferase
KM406_RS14035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM406_RS14040	COG5146	pantothenate kinase activity
KM406_RS14060	COG1131	(ABC) transporter
KM406_RS14105	COG0628	permease
KM406_RS14120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM406_RS14125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM406_RS14130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM406_RS14135	COG1116	anion transmembrane transporter activity
KM406_RS14155	COG2816	NAD+ diphosphatase activity
KM406_RS14175	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM406_RS14200	COG0697	spore germination
KM406_RS14205	COG2318	DinB family
KM406_RS14225	COG4912	Dna alkylation repair
KM406_RS14245	COG0861	Integral membrane protein TerC family
KM406_RS14250	COG1368	sulfuric ester hydrolase activity
KM406_RS14255	COG0488	(ABC) transporter
KM406_RS14270	COG1309	transcriptional regulator
KM406_RS14285	COG0287	Prephenate dehydrogenase
KM406_RS14290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM406_RS14295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM406_RS14300	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM406_RS14300	COG1605	Chorismate mutase
KM406_RS14335	COG3584	3D domain protein
KM406_RS14335	COG1388	LysM domain
KM406_RS14345	COG1595	DNA-templated transcription, initiation
KM406_RS14370	COG1879	ABC-type sugar transport system periplasmic component
KM406_RS14380	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM406_RS14390	COG2390	Transcriptional regulator
KM406_RS14395	COG1070	Carbohydrate kinase
KM406_RS14425	COG2329	Antibiotic biosynthesis monooxygenase
KM406_RS14445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS14455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM406_RS14460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM406_RS14465	COG4187	Peptidase family M20/M25/M40
KM406_RS14470	COG1414	Transcriptional regulator
KM406_RS14475	COG0833	amino acid
KM406_RS14480	COG1690	Belongs to the RtcB family
KM406_RS14490	COG1785	Belongs to the alkaline phosphatase family
KM406_RS14500	COG3655	Transcriptional regulator
KM406_RS14515	COG4377	Putative membrane peptidase family (DUF2324)
KM406_RS14525	COG3279	Response regulator of the LytR AlgR family
KM406_RS14535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS14540	COG0346	lactoylglutathione lyase activity
KM406_RS14560	COG0714	Associated with various cellular activities
KM406_RS14585	COG0463	Glycosyl transferase, family 2
KM406_RS14605	COG0463	Glycosyl transferase, family 2
KM406_RS14615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM406_RS14620	COG0753	catalase activity
KM406_RS14630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM406_RS14655	COG0714	Associated with various cellular activities
KM406_RS14665	COG0778	Nitroreductase
KM406_RS14670	COG1846	Transcriptional regulator
KM406_RS14705	COG1725	Transcriptional regulator
KM406_RS14715	COG0577	efflux transmembrane transporter activity
KM406_RS14715	COG1136	(ABC) transporter
KM406_RS14740	COG2207	Transcriptional regulator
KM406_RS14745	COG0456	acetyltransferase
KM406_RS14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS14785	COG0642	Histidine kinase
KM406_RS14790	COG0745	RESPONSE REGULATOR receiver
KM406_RS14795	COG0596	Alpha beta hydrolase
KM406_RS14825	COG0730	response to heat
KM406_RS14835	COG0833	amino acid
KM406_RS14845	COG4335	DNA alkylation repair
KM406_RS14885	COG0768	penicillin binding
KM406_RS14895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM406_RS14930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM406_RS14935	COG1414	Transcriptional regulator
KM406_RS14950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM406_RS14955	COG0640	Transcriptional regulator
KM406_RS14965	COG1960	acyl-CoA dehydrogenase activity
KM406_RS14980	COG3314	Sporulation integral membrane protein YlbJ
KM406_RS14995	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM406_RS15010	COG0574	Belongs to the PEP-utilizing enzyme family
KM406_RS15010	COG3848	Pyruvate phosphate dikinase
KM406_RS15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS15030	COG5577	PFAM Coat F domain
KM406_RS15035	COG3403	YqcI/YcgG family
KM406_RS15040	COG1280	lysine exporter protein (LysE YggA)
KM406_RS15075	COG1063	alcohol dehydrogenase
KM406_RS15090	COG1027	Aspartate ammonia-lyase
KM406_RS15095	COG0252	asparaginase activity
KM406_RS15100	COG1396	sequence-specific DNA binding
KM406_RS15110	COG0322	excinuclease ABC activity
KM406_RS15115	COG0531	amino acid
KM406_RS15120	COG1114	Component of the transport system for branched-chain amino acids
KM406_RS15125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM406_RS15135	COG0281	malic enzyme
KM406_RS15150	COG0531	amino acid
KM406_RS15160	COG0784	Response regulator, receiver
KM406_RS15170	COG2066	Belongs to the glutaminase family
KM406_RS15175	COG1115	amino acid carrier protein
KM406_RS15205	COG0737	Belongs to the 5'-nucleotidase family
KM406_RS15210	COG0753	catalase activity
KM406_RS15215	COG2267	carboxylic ester hydrolase activity
KM406_RS15220	COG1335	isochorismatase
KM406_RS15240	COG0583	DNA-binding transcription factor activity
KM406_RS15290	COG0415	Belongs to the DNA photolyase family
KM406_RS15295	COG0288	reversible hydration of carbon dioxide
KM406_RS15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM406_RS15310	COG5609	conserved protein (DUF2294)
KM406_RS15325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM406_RS15330	COG2267	carboxylic ester hydrolase activity
KM406_RS15335	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM406_RS15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM406_RS15345	COG1121	(ABC) transporter
KM406_RS15375	COG0798	PFAM Bile acid sodium symporter
KM406_RS15380	COG0346	lactoylglutathione lyase activity
KM406_RS15385	COG0640	Transcriptional regulator
KM406_RS15400	COG0443	Heat shock 70 kDa protein
KM406_RS15415	COG1522	sequence-specific DNA binding
KM406_RS15430	COG0346	lactoylglutathione lyase activity
KM406_RS15450	COG2169	Transcriptional regulator
KM406_RS15455	COG2169	Transcriptional regulator
KM406_RS15500	COG2814	Major facilitator Superfamily
KM406_RS15525	COG0745	RESPONSE REGULATOR receiver
KM406_RS15530	COG3850	Histidine kinase
KM406_RS15530	COG5002	protein histidine kinase activity
KM406_RS15555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM406_RS15575	COG1476	TRANSCRIPTIONal
KM406_RS15590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS15595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM406_RS15605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM406_RS15610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM406_RS15625	COG1136	(ABC) transporter
KM406_RS15630	COG0577	efflux transmembrane transporter activity
KM406_RS15645	COG3850	Histidine kinase
KM406_RS15645	COG5002	protein histidine kinase activity
KM406_RS15655	COG2364	Membrane
KM406_RS15660	COG1846	Transcriptional regulator
KM406_RS15670	COG2808	Putative FMN-binding domain
KM406_RS15675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS15680	COG2271	Major facilitator Superfamily
KM406_RS15685	COG1556	Lactate utilization protein
KM406_RS15690	COG1139	Iron-sulfur cluster binding protein
KM406_RS15700	COG0583	DNA-binding transcription factor activity
KM406_RS15710	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM406_RS15730	COG0738	Major facilitator superfamily
KM406_RS15735	COG0673	inositol 2-dehydrogenase activity
KM406_RS15740	COG0561	phosphatase activity
KM406_RS15750	COG1609	Transcriptional regulator
KM406_RS15755	COG0457	Tetratricopeptide repeat
KM406_RS15775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM406_RS15805	COG0534	Mate efflux family protein
KM406_RS15825	COG2814	Major facilitator Superfamily
KM406_RS15830	COG1309	transcriptional regulator
KM406_RS15845	COG0814	amino acid
KM406_RS15850	COG1760	l-serine dehydratase
KM406_RS15855	COG1760	l-serine dehydratase
KM406_RS15865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM406_RS15870	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM406_RS15880	COG1335	isochorismatase
KM406_RS15885	COG1522	sequence-specific DNA binding
KM406_RS15890	COG0531	amino acid
KM406_RS15910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM406_RS15930	COG1595	DNA-templated transcription, initiation
KM406_RS15945	COG0662	Cupin 2, conserved barrel domain protein
KM406_RS15950	COG2207	Transcriptional regulator
KM406_RS15950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM406_RS16000	COG0477	Major facilitator Superfamily
KM406_RS16010	COG1846	Transcriptional regulator
KM406_RS16015	COG2814	Major facilitator Superfamily
KM406_RS16025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM406_RS16030	COG1131	(ABC) transporter
KM406_RS16050	COG2076	Multidrug Resistance protein
KM406_RS16055	COG1309	transcriptional regulator
KM406_RS16065	COG2031	fatty acid transporter
KM406_RS16075	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM406_RS16105	COG1122	ATPase activity
KM406_RS16110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM406_RS16125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM406_RS16130	COG1288	antiporter activity
KM406_RS16135	COG2356	endonuclease I
KM406_RS16150	COG3620	sequence-specific DNA binding
KM406_RS16155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM406_RS16160	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM406_RS16165	COG0124	histidyl-tRNA synthetase
KM406_RS16180	COG1733	regulation of RNA biosynthetic process
KM406_RS16185	COG0778	Nitroreductase
KM406_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS16215	COG1131	(ABC) transporter
KM406_RS16240	COG1011	Hydrolase
KM406_RS16250	COG2365	Tyrosine phosphatase family
KM406_RS16275	COG0346	lactoylglutathione lyase activity
KM406_RS16280	COG1940	carbohydrate kinase activity
KM406_RS16285	COG0738	Major facilitator superfamily
KM406_RS16290	COG0110	maltose O-acetyltransferase activity
KM406_RS16300	COG0577	efflux transmembrane transporter activity
KM406_RS16300	COG1136	(ABC) transporter
KM406_RS16315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM406_RS16320	COG0628	permease
KM406_RS16340	COG2226	methyltransferase
KM406_RS16350	COG0477	Major facilitator Superfamily
KM406_RS16380	COG1253	flavin adenine dinucleotide binding
KM406_RS16385	COG0789	Transcriptional regulator
KM406_RS16390	COG0697	spore germination
KM406_RS16395	COG1357	PFAM Pentapeptide repeats (8 copies)
KM406_RS16400	COG3813	Protein conserved in bacteria
KM406_RS16405	COG2706	6-phosphogluconolactonase activity
KM406_RS16410	COG1070	Carbohydrate kinase
KM406_RS16420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM406_RS16425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM406_RS16435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM406_RS16440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM406_RS16445	COG0604	alcohol dehydrogenase
KM406_RS16450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM406_RS16460	COG0604	alcohol dehydrogenase
KM406_RS16460	COG3321	synthase
KM406_RS16465	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS16490	COG0656	L-ascorbic acid biosynthetic process
KM406_RS16495	COG2814	Major facilitator Superfamily
KM406_RS16510	COG0346	lactoylglutathione lyase activity
KM406_RS16515	COG0814	amino acid
KM406_RS16540	COG1393	Belongs to the ArsC family
KM406_RS16545	COG1733	regulation of RNA biosynthetic process
KM406_RS16550	COG2188	Transcriptional regulator
KM406_RS16560	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM406_RS16565	COG1733	regulation of RNA biosynthetic process
KM406_RS16570	COG1733	regulation of RNA biosynthetic process
KM406_RS16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS16605	COG0384	phenazine biosynthesis protein PhzF
KM406_RS16615	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS16625	COG0318	PFAM AMP-dependent synthetase and ligase
KM406_RS16635	COG1733	regulation of RNA biosynthetic process
KM406_RS16665	COG1191	sigma factor activity
KM406_RS16680	COG1309	transcriptional regulator
KM406_RS16700	COG3152	Membrane
KM406_RS16725	COG1151	hydroxylamine reductase activity
KM406_RS16735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS16740	COG3409	Peptidoglycan-binding domain 1 protein
KM406_RS16740	COG3757	hydrolase, family 25
KM406_RS16775	COG2072	flavoprotein involved in K transport
KM406_RS16810	COG0604	alcohol dehydrogenase
KM406_RS16815	COG1113	amino acid transport
KM406_RS16820	COG2814	Major facilitator Superfamily
KM406_RS16850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM406_RS16855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM406_RS16880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS16890	COG3739	integral membrane protein
KM406_RS16895	COG0384	phenazine biosynthesis protein PhzF
KM406_RS16925	COG0583	DNA-binding transcription factor activity
KM406_RS16945	COG1193	negative regulation of DNA recombination
KM406_RS16970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM406_RS17000	COG0584	glycerophosphoryl diester phosphodiesterase
KM406_RS17025	COG0640	Transcriptional regulator
KM406_RS17030	COG0604	alcohol dehydrogenase
KM406_RS17050	COG2808	Putative FMN-binding domain
KM406_RS17055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM406_RS17065	COG0385	Bile acid
KM406_RS17070	COG0277	FAD linked oxidase domain protein
KM406_RS17100	COG1216	Glycosyl transferase, family 2
KM406_RS17105	COG1024	Enoyl-CoA hydratase
KM406_RS17115	COG1285	pathogenesis
KM406_RS17130	COG2514	catechol 2,3-dioxygenase activity
KM406_RS17135	COG2720	vancomycin resistance protein
KM406_RS17175	COG0716	FMN binding
KM406_RS17205	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS17215	COG0165	Argininosuccinate lyase
KM406_RS17230	COG4145	pantothenate transmembrane transporter activity
KM406_RS17240	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS17245	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS17255	COG1657	PFAM Prenyltransferase squalene oxidase
KM406_RS17260	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM406_RS17265	COG2962	Rard protein
KM406_RS17270	COG3326	Membrane
KM406_RS17285	COG0489	protein tyrosine kinase activity
KM406_RS17295	COG0314	molybdopterin synthase activity
KM406_RS17300	COG0303	'Molybdopterin
KM406_RS17305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM406_RS17310	COG2116	formate transmembrane transporter activity
KM406_RS17320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM406_RS17325	COG5609	conserved protein (DUF2294)
KM406_RS17330	COG2427	Protein of unknown function (DUF1641)
KM406_RS17335	COG3383	formate dehydrogenase (NAD+) activity
KM406_RS17345	COG0697	spore germination
KM406_RS17385	COG2226	methyltransferase
KM406_RS17390	COG4166	transmembrane transport
KM406_RS17395	COG4166	transmembrane transport
KM406_RS17400	COG4166	transmembrane transport
KM406_RS17405	COG1301	dicarboxylic acid transport
KM406_RS17410	COG1316	TRANSCRIPTIONal
KM406_RS17420	COG1595	DNA-templated transcription, initiation
KM406_RS17440	COG1131	(ABC) transporter
KM406_RS17450	COG0673	inositol 2-dehydrogenase activity
KM406_RS17455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM406_RS17460	COG0187	DNA topoisomerase II activity
KM406_RS17465	COG1832	CoA-binding protein
KM406_RS17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM406_RS17475	COG0745	RESPONSE REGULATOR receiver
KM406_RS17490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM406_RS17495	COG4841	protein insertion into membrane
KM406_RS17500	COG0824	Thioesterase
KM406_RS17530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM406_RS17540	COG2274	protein secretion by the type I secretion system
KM406_RS17545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM406_RS17585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM406_RS17600	COG0183	Belongs to the thiolase family
KM406_RS17605	COG0318	PFAM AMP-dependent synthetase and ligase
KM406_RS17610	COG1268	BioY protein
KM406_RS17615	COG0318	PFAM AMP-dependent synthetase and ligase
KM406_RS17665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS17675	COG5002	protein histidine kinase activity
KM406_RS17680	COG0400	carboxylic ester hydrolase activity
KM406_RS17685	COG0346	lactoylglutathione lyase activity
KM406_RS17690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM406_RS17695	COG0069	glutamate synthase activity
KM406_RS17700	COG1902	pentaerythritol trinitrate reductase activity
KM406_RS17705	COG1329	Transcriptional regulator
KM406_RS17710	COG0010	Belongs to the arginase family
KM406_RS17735	COG2226	methyltransferase
KM406_RS17770	COG4846	Membrane protein involved in cytochrome C biogenesis
KM406_RS17775	COG0785	Cytochrome C biogenesis protein
KM406_RS17785	COG0583	DNA-binding transcription factor activity
KM406_RS17790	COG1380	Effector of murein hydrolase LrgA
KM406_RS17795	COG1346	cytolysis
KM406_RS17820	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM406_RS17820	COG3409	Peptidoglycan-binding domain 1 protein
KM406_RS17835	COG1132	(ABC) transporter
KM406_RS17840	COG1132	(ABC) transporter
KM406_RS17870	COG3639	organic phosphonate transmembrane transporter activity
KM406_RS17875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM406_RS17895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM406_RS17915	COG1695	Transcriptional regulator
KM406_RS17955	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM406_RS17955	COG1388	LysM domain
KM406_RS17955	COG3409	Peptidoglycan-binding domain 1 protein
KM406_RS17960	COG4824	toxin secretion phage lysis holin
KM406_RS18115	COG1595	DNA-templated transcription, initiation
KM406_RS18160	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM406_RS18240	COG1396	sequence-specific DNA binding
KM406_RS18265	COG0174	glutamine synthetase
KM406_RS18270	COG0789	Transcriptional regulator
KM406_RS18275	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM406_RS18285	COG2860	membrane
KM406_RS18290	COG0464	growth
KM406_RS18320	COG1388	LysM domain
KM406_RS18320	COG3584	3D domain protein
KM406_RS18325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM406_RS18325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM406_RS18325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM406_RS18330	COG1105	Belongs to the carbohydrate kinase PfkB family
KM406_RS18335	COG1349	DNA-binding transcription factor activity
KM406_RS18345	COG2322	membrane
KM406_RS18355	COG1113	amino acid transport
KM406_RS18370	COG1408	metallophosphoesterase
KM406_RS18375	COG2116	formate transmembrane transporter activity
KM406_RS18385	COG2217	Heavy metal translocating P-type atpase
KM406_RS18390	COG2608	mercury ion transmembrane transporter activity
KM406_RS18395	COG1937	Protein conserved in bacteria
KM406_RS18405	COG2819	hydrolase of the alpha beta superfamily
KM406_RS18410	COG1120	ATPase activity
KM406_RS18415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS18420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS18430	COG0708	Exodeoxyribonuclease III
KM406_RS18435	COG2169	Transcriptional regulator
KM406_RS18440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM406_RS18445	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM406_RS18455	COG2364	Membrane
KM406_RS18470	COG2267	carboxylic ester hydrolase activity
KM406_RS18475	COG0346	lactoylglutathione lyase activity
KM406_RS18480	COG3300	MHYT domain
KM406_RS18480	COG5001	Diguanylate cyclase
KM406_RS18500	COG1346	cytolysis
KM406_RS18505	COG1380	Effector of murein hydrolase LrgA
KM406_RS18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM406_RS18515	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM406_RS18515	COG0596	Alpha beta hydrolase
KM406_RS18520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM406_RS18540	COG1404	Belongs to the peptidase S8 family
KM406_RS18545	COG3773	Cell wall hydrolase
KM406_RS18550	COG0562	UDP-galactopyranose mutase
KM406_RS18555	COG1368	sulfuric ester hydrolase activity
KM406_RS18560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM406_RS18570	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM406_RS18595	COG1131	(ABC) transporter
KM406_RS18615	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM406_RS18620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM406_RS18625	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM406_RS18630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM406_RS18630	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM406_RS18640	COG2359	stage V sporulation protein S
KM406_RS18645	COG1692	metallophosphoesterase
KM406_RS18670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM406_RS18675	COG1426	Protein conserved in bacteria
KM406_RS18690	COG0300	oxidoreductase activity
KM406_RS18695	COG0612	Peptidase, M16
KM406_RS18700	COG0612	Peptidase, M16
KM406_RS18705	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM406_RS18715	COG3845	ABC transporter
KM406_RS18720	COG1744	ABC transporter substrate-binding protein PnrA-like
KM406_RS18725	COG2188	Transcriptional regulator
KM406_RS18730	COG1674	ftsk spoiiie
KM406_RS18740	COG0740	serine-type endopeptidase activity
KM406_RS18745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM406_RS18755	COG0527	aspartate kinase activity
KM406_RS18760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM406_RS18765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM406_RS18770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM406_RS18775	COG1873	PFAM PRC-barrel domain
KM406_RS18780	COG0612	Peptidase, M16
KM406_RS18785	COG0726	polysaccharide deacetylase
KM406_RS18800	COG0196	riboflavin kinase activity
KM406_RS18805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM406_RS18815	COG1550	Protein conserved in bacteria
KM406_RS18825	COG1358	cellular component organization or biogenesis
KM406_RS18830	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM406_RS18835	COG0195	Participates in both transcription termination and antitermination
KM406_RS18855	COG0750	zinc metalloprotease
KM406_RS18865	COG4589	Belongs to the CDS family
KM406_RS18870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM406_RS18880	COG0528	UMP kinase activity
KM406_RS18910	COG4974	Belongs to the 'phage' integrase family
KM406_RS18920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM406_RS18930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM406_RS18970	COG1837	Belongs to the UPF0109 family
KM406_RS18980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM406_RS18990	COG0552	protein localization to endoplasmic reticulum
KM406_RS18995	COG1196	nuclear chromosome segregation
KM406_RS19005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM406_RS19010	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS19015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM406_RS19030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM406_RS19035	COG1461	Dihydroxyacetone kinase
KM406_RS19040	COG1302	Protein conserved in bacteria
KM406_RS19055	COG1564	THIamine pyrophosphokinase
KM406_RS19060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM406_RS19065	COG1162	GTPase activity
KM406_RS19070	COG2815	serine threonine protein kinase
KM406_RS19070	COG0515	serine threonine protein kinase
KM406_RS19075	COG0631	protein serine/threonine phosphatase activity
KM406_RS19085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM406_RS19085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM406_RS19095	COG0242	peptide deformylase activity
KM406_RS19100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM406_RS19105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM406_RS19125	COG1561	YicC-like family, N-terminal region
KM406_RS19130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM406_RS19140	COG0006	proline dipeptidase activity
KM406_RS19155	COG3069	C4-dicarboxylate transmembrane transporter activity
KM406_RS19220	COG0564	pseudouridine synthase activity
KM406_RS19240	COG3599	regulation of cell shape
KM406_RS19245	COG2302	S4 RNA-binding domain
KM406_RS19250	COG0762	integral membrane protein
KM406_RS19260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM406_RS19265	COG1496	oxidoreductase activity
KM406_RS19270	COG1873	PFAM PRC-barrel domain
KM406_RS19275	COG1191	sigma factor activity
KM406_RS19280	COG1191	sigma factor activity
KM406_RS19290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM406_RS19295	COG0849	cell division
KM406_RS19300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM406_RS19305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM406_RS19315	COG0772	Belongs to the SEDS family
KM406_RS19330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM406_RS19335	COG0768	penicillin binding
KM406_RS19340	COG0768	penicillin binding
KM406_RS19345	COG4839	cell division protein FtsL
KM406_RS19360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM406_RS19375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM406_RS19380	COG1399	metal-binding, possibly nucleic acid-binding protein
KM406_RS19430	COG4824	toxin secretion phage lysis holin
KM406_RS19525	COG4626	Terminase
KM406_RS19525	COG1802	Transcriptional regulator
KM406_RS19615	COG0756	dUTP diphosphatase activity
KM406_RS19630	COG1191	sigma factor activity
KM406_RS19655	COG1484	DNA-dependent DNA replication
KM406_RS19685	COG1396	sequence-specific DNA binding
KM406_RS19700	COG1396	sequence-specific DNA binding
KM406_RS19715	COG0582	viral genome integration into host DNA
KM406_RS19725	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM406_RS19730	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM406_RS19735	COG3314	Sporulation integral membrane protein YlbJ
KM406_RS19745	COG0742	ribosomal rna small subunit methyltransferase
KM406_RS19760	COG3679	Belongs to the UPF0342 family
KM406_RS19765	COG0406	alpha-ribazole phosphatase activity
KM406_RS19780	COG2340	Cysteine-rich secretory protein family
KM406_RS19795	COG3336	cytochrome c oxidase
KM406_RS19830	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM406_RS19835	COG0772	Belongs to the SEDS family
KM406_RS19845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM406_RS19850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM406_RS19860	COG4896	Protein conserved in bacteria
KM406_RS19875	COG1217	gtp-binding protein TYPA
KM406_RS19885	COG0483	inositol monophosphate 1-phosphatase activity
KM406_RS19905	COG1982	Orn Lys Arg decarboxylase major
KM406_RS19950	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM406_RS19955	COG0022	dehydrogenase e1 component
KM406_RS19960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM406_RS19970	COG0242	peptide deformylase activity
KM406_RS19975	COG0561	phosphatase activity
KM406_RS19985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM406_RS19990	COG0569	domain protein
KM406_RS20010	COG0583	DNA-binding transcription factor activity
KM406_RS20015	COG0517	IMP dehydrogenase activity
KM406_RS20025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM406_RS20035	COG4703	Protein of unknown function (DUF1797)
KM406_RS20050	COG2200	EAL domain
KM406_RS20055	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS20060	COG1408	metallophosphoesterase
KM406_RS20070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM406_RS20105	COG2814	Major facilitator Superfamily
KM406_RS20125	COG3209	COG3209 Rhs family protein
KM406_RS20135	COG2205	protein histidine kinase activity
KM406_RS20145	COG0436	Aminotransferase
KM406_RS20150	COG1609	Transcriptional regulator
KM406_RS20155	COG3833	ABC-type maltose transport systems, permease component
KM406_RS20160	COG1175	transmembrane transport
KM406_RS20165	COG2182	Extracellular solute-binding protein
KM406_RS20175	COG0366	Alpha amylase catalytic
KM406_RS20180	COG3842	ATPase activity
KM406_RS20220	COG0183	Belongs to the thiolase family
KM406_RS20255	COG1695	Transcriptional regulator
KM406_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS20270	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM406_RS20280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM406_RS20285	COG0436	Aminotransferase
KM406_RS20305	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM406_RS20325	COG2199	diguanylate cyclase activity
KM406_RS20330	COG0778	Nitroreductase
KM406_RS20355	COG1263	PTS System
KM406_RS20355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM406_RS20355	COG2190	(PTS) system
KM406_RS20360	COG3711	transcriptional antiterminator
KM406_RS20370	COG2188	Transcriptional regulator
KM406_RS20380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM406_RS20405	COG1547	Domain of unknown function (DUF309)
KM406_RS20410	COG0456	acetyltransferase
KM406_RS20420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM406_RS20425	COG4086	secreted protein
KM406_RS20430	COG0561	phosphatase activity
KM406_RS20435	COG0697	spore germination
KM406_RS20450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM406_RS20475	COG0733	neurotransmitter:sodium symporter activity
KM406_RS20495	COG1686	Belongs to the peptidase S11 family
KM406_RS20500	COG1725	Transcriptional regulator
KM406_RS20505	COG1131	(ABC) transporter
KM406_RS20520	COG1846	Transcriptional regulator
KM406_RS20535	COG0598	Magnesium transport protein CorA
KM406_RS20560	COG4974	Belongs to the 'phage' integrase family
KM406_RS20570	COG0735	belongs to the Fur family
KM406_RS20575	COG1300	Membrane
KM406_RS20595	COG0667	Aldo Keto reductase
KM406_RS20600	COG0656	L-ascorbic acid biosynthetic process
KM406_RS20605	COG0456	acetyltransferase
KM406_RS20605	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM406_RS20615	COG4085	toxin activity
KM406_RS20615	COG1525	nuclease
KM406_RS20615	COG0737	Belongs to the 5'-nucleotidase family
KM406_RS20625	COG0596	Alpha beta hydrolase
KM406_RS20630	COG2056	Na+-H+ antiporter family
KM406_RS20635	COG1609	Transcriptional regulator
KM406_RS20640	COG0456	acetyltransferase
KM406_RS20645	COG1073	alpha beta
KM406_RS20660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM406_RS20660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM406_RS20665	COG0307	riboflavin synthase, alpha
KM406_RS20690	COG4106	trans-aconitate 2-methyltransferase activity
KM406_RS20695	COG2226	methyltransferase
KM406_RS20695	COG1073	alpha beta
KM406_RS20710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM406_RS20720	COG1757	Na H antiporter
KM406_RS20725	COG0737	Belongs to the 5'-nucleotidase family
KM406_RS20735	COG1522	sequence-specific DNA binding
KM406_RS20755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM406_RS20765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM406_RS20780	COG0300	oxidoreductase activity
KM406_RS20790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM406_RS20795	COG1760	l-serine dehydratase
KM406_RS20800	COG1760	l-serine dehydratase
KM406_RS20820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM406_RS20830	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM406_RS20835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS20850	COG1376	ErfK ybiS ycfS ynhG family protein
KM406_RS20855	COG4129	membrane
KM406_RS20860	COG1126	abc transporter atp-binding protein
KM406_RS20865	COG0765	amino acid transport
KM406_RS20870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM406_RS20885	COG2816	NAD+ diphosphatase activity
KM406_RS20890	COG0772	Belongs to the SEDS family
KM406_RS20895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM406_RS20900	COG0022	dehydrogenase e1 component
KM406_RS20905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM406_RS20910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM406_RS20925	COG0280	phosphate acetyltransferase
KM406_RS20930	COG3829	transcription factor binding
KM406_RS20930	COG3290	protein histidine kinase activity
KM406_RS20940	COG0584	glycerophosphoryl diester phosphodiesterase
KM406_RS20945	COG3093	addiction module antidote protein HigA
KM406_RS20955	COG0745	RESPONSE REGULATOR receiver
KM406_RS20960	COG0750	zinc metalloprotease
KM406_RS20965	COG0497	DNA recombination
KM406_RS20975	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM406_RS20985	COG0142	geranyltranstransferase activity
KM406_RS21010	COG1302	Protein conserved in bacteria
KM406_RS21015	COG0439	Biotin carboxylase
KM406_RS21020	COG0511	ligase activity, forming carbon-carbon bonds
KM406_RS21065	COG3854	ATPases associated with a variety of cellular activities
KM406_RS21090	COG0006	proline dipeptidase activity
KM406_RS21105	COG3872	metal-dependent enzyme
KM406_RS21115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM406_RS21135	COG0095	Lipoate-protein ligase
KM406_RS21140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM406_RS21145	COG1609	Transcriptional regulator
KM406_RS21155	COG2076	Multidrug Resistance protein
KM406_RS21160	COG2076	Multidrug Resistance protein
KM406_RS21195	COG1131	(ABC) transporter
KM406_RS21200	COG1725	Transcriptional regulator
KM406_RS21230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM406_RS21285	COG4970	Tfp pilus assembly protein FimT
KM406_RS21295	COG1459	type II secretion system
KM406_RS21300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM406_RS21350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM406_RS21355	COG1410	methionine synthase
KM406_RS21355	COG0646	methionine synthase
KM406_RS21360	COG0646	methionine synthase
KM406_RS21360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM406_RS21365	COG0626	cystathionine gamma-synthase activity
KM406_RS21370	COG0626	cystathionine gamma-synthase activity
KM406_RS21390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS21400	COG1940	carbohydrate kinase activity
KM406_RS21405	COG4483	Protein conserved in bacteria
KM406_RS21410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM406_RS21415	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM406_RS21420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM406_RS21425	COG0704	Plays a role in the regulation of phosphate uptake
KM406_RS21435	COG0581	inorganic phosphate transmembrane transporter activity
KM406_RS21440	COG0573	inorganic phosphate transmembrane transporter activity
KM406_RS21445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM406_RS21450	COG0768	penicillin binding
KM406_RS21455	COG0477	Major facilitator Superfamily
KM406_RS21460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM406_RS21485	COG0735	belongs to the Fur family
KM406_RS21490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM406_RS21495	COG1121	(ABC) transporter
KM406_RS21500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS21530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM406_RS21535	COG2384	SAM-dependent methyltransferase
KM406_RS21540	COG2010	Cytochrome c
KM406_RS21545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM406_RS21550	COG0358	DNA primase activity
KM406_RS21560	COG0517	IMP dehydrogenase activity
KM406_RS21575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM406_RS21580	COG0295	cytidine deaminase activity
KM406_RS21585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM406_RS21595	COG1480	7TM receptor with intracellular HD hydrolase
KM406_RS21600	COG1702	phosphate starvation-inducible protein PhoH
KM406_RS21615	COG1610	YqeY-like protein
KM406_RS21620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM406_RS21625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM406_RS21630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM406_RS21660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM406_RS21665	COG1733	regulation of RNA biosynthetic process
KM406_RS21690	COG1466	dna polymerase III delta subunit
KM406_RS21700	COG0658	competence protein
KM406_RS21700	COG2333	competence protein COMEC
KM406_RS21705	COG2131	deaminase
KM406_RS21710	COG1596	polysaccharide export
KM406_RS21710	COG1555	photosystem II stabilization
KM406_RS21715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM406_RS21720	COG2226	methyltransferase
KM406_RS21725	COG0799	negative regulation of ribosome biogenesis
KM406_RS21730	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM406_RS21740	COG1534	Rna-binding protein
KM406_RS21750	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM406_RS21755	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM406_RS21780	COG1595	DNA-templated transcription, initiation
KM406_RS21790	COG0778	Nitroreductase
KM406_RS21795	COG2357	RelA SpoT domain protein
KM406_RS21805	COG1785	Belongs to the alkaline phosphatase family
KM406_RS21815	COG2267	carboxylic ester hydrolase activity
KM406_RS21850	COG1404	Belongs to the peptidase S8 family
KM406_RS21855	COG3186	Phenylalanine-4-hydroxylase
KM406_RS21870	COG2259	Doxx family
KM406_RS21910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM406_RS21920	COG1012	belongs to the aldehyde dehydrogenase family
KM406_RS21920	COG1454	alcohol dehydrogenase
KM406_RS21925	COG0626	cystathionine gamma-synthase activity
KM406_RS21930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM406_RS21955	COG0768	penicillin binding
KM406_RS21970	COG0826	peptidase U32
KM406_RS21975	COG0826	peptidase U32
KM406_RS21980	COG4122	O-methyltransferase activity
KM406_RS21985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM406_RS22005	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM406_RS22015	COG0628	permease
KM406_RS22035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM406_RS22045	COG0482	sulfurtransferase activity
KM406_RS22050	COG1104	cysteine desulfurase activity
KM406_RS22055	COG1959	2 iron, 2 sulfur cluster binding
KM406_RS22060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM406_RS22070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM406_RS22095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM406_RS22105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM406_RS22105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM406_RS22110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM406_RS22115	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM406_RS22115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM406_RS22125	COG2244	polysaccharide biosynthetic process
KM406_RS22130	COG2323	membrane
KM406_RS22140	COG1862	Preprotein translocase
KM406_RS22170	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM406_RS22180	COG0697	spore germination
KM406_RS22185	COG0697	spore germination
KM406_RS22190	COG0640	Transcriptional regulator
KM406_RS22215	COG0157	Belongs to the NadC ModD family
KM406_RS22220	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM406_RS22225	COG1104	cysteine desulfurase activity
KM406_RS22230	COG1827	regulation of RNA biosynthetic process
KM406_RS22235	COG2258	MOSC domain
KM406_RS22240	COG0077	Prephenate dehydratase
KM406_RS22245	COG0577	efflux transmembrane transporter activity
KM406_RS22250	COG0577	efflux transmembrane transporter activity
KM406_RS22255	COG1136	(ABC) transporter
KM406_RS22265	COG0745	RESPONSE REGULATOR receiver
KM406_RS22270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM406_RS22275	COG3290	protein histidine kinase activity
KM406_RS22285	COG2868	ribosomal protein
KM406_RS22295	COG1530	ribonuclease E activity
KM406_RS22300	COG1994	Peptidase M50
KM406_RS22305	COG0739	heme binding
KM406_RS22310	COG2894	cell division
KM406_RS22330	COG1077	Cell shape determining protein MreB Mrl
KM406_RS22350	COG0285	dihydrofolate synthase activity
KM406_RS22355	COG0525	valine-tRNA ligase activity
KM406_RS22365	COG1388	LysM domain
KM406_RS22375	COG0113	porphobilinogen synthase activity
KM406_RS22380	COG1587	Uroporphyrinogen-III synthase
KM406_RS22390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM406_RS22400	COG1846	Transcriptional regulator
KM406_RS22405	COG1764	response to oxidative stress
KM406_RS22420	COG0470	DNA polymerase III
KM406_RS22420	COG1067	ATP-dependent peptidase activity
KM406_RS22465	COG0622	Phosphoesterase
KM406_RS22480	COG5401	PFAM Sporulation and spore germination
KM406_RS22500	COG1309	transcriptional regulator
KM406_RS22515	COG2197	response regulator
KM406_RS22520	COG2233	PERMEase
KM406_RS22530	COG0402	S-adenosylhomocysteine deaminase activity
KM406_RS22535	COG0402	S-adenosylhomocysteine deaminase activity
KM406_RS22545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM406_RS22555	COG0444	Belongs to the ABC transporter superfamily
KM406_RS22560	COG4608	Belongs to the ABC transporter superfamily
KM406_RS22565	COG3275	phosphorelay sensor kinase activity
KM406_RS22570	COG3279	Response regulator of the LytR AlgR family
KM406_RS22585	COG1983	PspC domain protein
KM406_RS22590	COG1396	sequence-specific DNA binding
KM406_RS22595	COG0697	spore germination
KM406_RS22605	COG1959	2 iron, 2 sulfur cluster binding
KM406_RS22610	COG1668	transmembrane transport
KM406_RS22615	COG4152	abc transporter atp-binding protein
KM406_RS22620	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM406_RS22630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM406_RS22635	COG1876	peptidase activity
KM406_RS22640	COG0824	Thioesterase
KM406_RS22645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM406_RS22650	COG1053	succinate dehydrogenase
KM406_RS22655	COG2009	succinate dehydrogenase
KM406_RS22660	COG1719	4-vinyl reductase, 4VR
KM406_RS22670	COG3118	belongs to the thioredoxin family
KM406_RS22675	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM406_RS22680	COG2086	electron transfer activity
KM406_RS22685	COG1024	Enoyl-CoA hydratase
KM406_RS22695	COG0318	PFAM AMP-dependent synthetase and ligase
KM406_RS22715	COG2318	DinB family
KM406_RS22745	COG1131	(ABC) transporter
KM406_RS22750	COG2205	protein histidine kinase activity
KM406_RS22755	COG0745	RESPONSE REGULATOR receiver
KM406_RS22765	COG4895	conserved protein (DUF2196)
KM406_RS22770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM406_RS22785	COG4509	Sortase family
KM406_RS22790	COG1120	ATPase activity
KM406_RS22805	COG5386	Cell surface protein
KM406_RS22815	COG5386	Cell surface protein
KM406_RS22820	COG1114	Component of the transport system for branched-chain amino acids
KM406_RS22825	COG1187	pseudouridine synthase activity
KM406_RS22835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM406_RS22835	COG1796	DNA polymerase
KM406_RS22840	COG1286	toxin biosynthetic process
KM406_RS22885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM406_RS22895	COG1418	mRNA catabolic process
KM406_RS22920	COG2814	Major facilitator Superfamily
KM406_RS22925	COG1566	PFAM secretion protein HlyD family protein
KM406_RS22930	COG1309	transcriptional regulator
KM406_RS22935	COG1363	Peptidase, m42
KM406_RS22960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM406_RS22970	COG1484	DNA-dependent DNA replication
KM406_RS22975	COG3611	Membrane attachment protein
KM406_RS22985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM406_RS22990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM406_RS22995	COG0237	dephospho-CoA kinase activity
KM406_RS23000	COG1971	Probably functions as a manganese efflux pump
KM406_RS23010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM406_RS23010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM406_RS23015	COG5002	protein histidine kinase activity
KM406_RS23020	COG0745	RESPONSE REGULATOR receiver
KM406_RS23040	COG0538	isocitrate dehydrogenase activity
KM406_RS23045	COG0372	Belongs to the citrate synthase family
KM406_RS23055	COG0628	permease
KM406_RS23060	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM406_RS23085	COG1725	Transcriptional regulator
KM406_RS23090	COG0281	malic enzyme
KM406_RS23095	COG0587	DNA-directed DNA polymerase activity
KM406_RS23110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM406_RS23130	COG4109	DRTGG domain
KM406_RS23145	COG0006	proline dipeptidase activity
KM406_RS23185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS23190	COG0662	Cupin 2, conserved barrel domain protein
KM406_RS23200	COG1476	TRANSCRIPTIONal
KM406_RS23215	COG1028	Short-chain dehydrogenase reductase Sdr
KM406_RS23220	COG0589	response to stress
KM406_RS23260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS23280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM406_RS23285	COG0827	DNA restriction-modification system
KM406_RS23290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM406_RS23295	COG3874	Sporulation protein YtfJ
KM406_RS23310	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM406_RS23320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM406_RS23335	COG1104	cysteine desulfurase activity
KM406_RS23345	COG0583	DNA-binding transcription factor activity
KM406_RS23350	COG0697	spore germination
KM406_RS23360	COG1956	GAF domain-containing protein
KM406_RS23365	COG0626	cystathionine gamma-synthase activity
KM406_RS23395	COG1595	DNA-templated transcription, initiation
KM406_RS23405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM406_RS23410	COG0454	-acetyltransferase
KM406_RS23415	COG0517	IMP dehydrogenase activity
KM406_RS23420	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM406_RS23430	COG0745	RESPONSE REGULATOR receiver
KM406_RS23440	COG0666	response to abiotic stimulus
KM406_RS23475	COG1609	Transcriptional regulator
KM406_RS23480	COG4851	CamS sex pheromone cAM373 precursor
KM406_RS23485	COG3118	belongs to the thioredoxin family
KM406_RS23495	COG2309	aminopeptidase activity
KM406_RS23515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS23530	COG1674	ftsk spoiiie
KM406_RS23540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM406_RS23545	COG4848	Belongs to the UPF0354 family
KM406_RS23550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM406_RS23555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM406_RS23560	COG1363	Peptidase, m42
KM406_RS23570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS23585	COG0510	thiamine kinase activity
KM406_RS23590	COG1523	belongs to the glycosyl hydrolase 13 family
KM406_RS23605	COG1349	DNA-binding transcription factor activity
KM406_RS23610	COG1187	pseudouridine synthase activity
KM406_RS23615	COG2244	polysaccharide biosynthetic process
KM406_RS23620	COG2081	HI0933 family
KM406_RS23625	COG2814	Major facilitator Superfamily
KM406_RS23635	COG3832	glyoxalase III activity
KM406_RS23655	COG1329	Transcriptional regulator
KM406_RS23665	COG4975	Glucose uptake
KM406_RS23680	COG0314	molybdopterin synthase activity
KM406_RS23685	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM406_RS23690	COG0303	'Molybdopterin
KM406_RS23700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM406_RS23725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM406_RS23735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM406_RS23775	COG2814	Major facilitator Superfamily
KM406_RS23780	COG0475	glutathione-regulated potassium exporter activity
KM406_RS23785	COG0490	domain, Protein
KM406_RS23790	COG0582	viral genome integration into host DNA
KM406_RS23800	COG1136	(ABC) transporter
KM406_RS23820	COG1242	4 iron, 4 sulfur cluster binding
KM406_RS23825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM406_RS23830	COG1131	(ABC) transporter
KM406_RS23840	COG1794	racemase activity, acting on amino acids and derivatives
KM406_RS23860	COG2267	carboxylic ester hydrolase activity
KM406_RS23865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM406_RS23870	COG0671	phosphoesterase, PA-phosphatase related
KM406_RS23875	COG0438	transferase activity, transferring glycosyl groups
KM406_RS23885	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM406_RS23935	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM406_RS23940	COG5002	protein histidine kinase activity
KM406_RS23945	COG4191	Histidine kinase
KM406_RS23950	COG2267	carboxylic ester hydrolase activity
KM406_RS23970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM406_RS23975	COG1116	anion transmembrane transporter activity
KM406_RS23980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM406_RS24005	COG0494	nUDIX hydrolase
KM406_RS24040	COG0288	reversible hydration of carbon dioxide
KM406_RS24045	COG1271	oxidase subunit
KM406_RS24050	COG1294	oxidase, subunit
KM406_RS24070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS24095	COG1842	Phage shock protein A
KM406_RS24125	COG5002	protein histidine kinase activity
KM406_RS24130	COG0745	RESPONSE REGULATOR receiver
KM406_RS24160	COG1597	lipid kinase activity
KM406_RS24195	COG0586	Pfam SNARE associated Golgi protein
KM406_RS24205	COG0577	efflux transmembrane transporter activity
KM406_RS24210	COG1136	(ABC) transporter
KM406_RS24215	COG3708	Transcriptional regulator
KM406_RS24215	COG2207	Transcriptional regulator
KM406_RS24220	COG0745	RESPONSE REGULATOR receiver
KM406_RS24225	COG2205	protein histidine kinase activity
KM406_RS24235	COG0577	efflux transmembrane transporter activity
KM406_RS24240	COG1136	(ABC) transporter
KM406_RS24260	COG2188	Transcriptional regulator
KM406_RS24280	COG3964	amidohydrolase
KM406_RS24310	COG4948	Mandelate Racemase Muconate Lactonizing
KM406_RS24320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM406_RS24325	COG0596	Alpha beta hydrolase
KM406_RS24330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM406_RS24335	COG1169	isochorismate synthase
KM406_RS24340	COG1575	Belongs to the MenA family. Type 1 subfamily
KM406_RS24345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM406_RS24365	COG0058	SHG alpha-glucan phosphorylase activity
KM406_RS24370	COG0297	glycogen (starch) synthase activity
KM406_RS24375	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM406_RS24490	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM406_RS24525	COG1285	pathogenesis
KM406_RS24530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM406_RS24540	COG0166	Belongs to the GPI family
KM406_RS24545	COG2155	Conserved Protein
KM406_RS24550	COG1098	S1 RNA binding domain
KM406_RS24555	COG0436	Aminotransferase
KM406_RS24560	COG1522	sequence-specific DNA binding
KM406_RS24565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM406_RS24570	COG2267	carboxylic ester hydrolase activity
KM406_RS24580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM406_RS24600	COG5018	Exonuclease
KM406_RS24605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM406_RS24625	COG2050	protein possibly involved in aromatic compounds catabolism
KM406_RS24635	COG1268	BioY protein
KM406_RS24645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM406_RS24650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM406_RS24665	COG3584	3D domain protein
KM406_RS24680	COG1252	NADH dehydrogenase
KM406_RS24695	COG3708	Transcriptional regulator
KM406_RS24710	COG1683	Conserved Protein
KM406_RS24730	COG0316	Belongs to the HesB IscA family
KM406_RS24745	COG1252	NADH dehydrogenase
KM406_RS24760	COG0390	transport system, permease component
KM406_RS24765	COG2824	Alkylphosphonate utilization operon protein PhnA
KM406_RS24805	COG4837	Protein of unknown function (DUF1462)
KM406_RS24810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM406_RS24820	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM406_RS24825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM406_RS24835	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM406_RS24840	COG0647	UMP catabolic process
KM406_RS24850	COG2445	Protein of unknown function DUF86
KM406_RS24855	COG1494	fructose-1,6-bisphosphatase
KM406_RS24870	COG4470	Protein conserved in bacteria
KM406_RS24880	COG0789	Transcriptional regulator
KM406_RS24885	COG4377	Putative membrane peptidase family (DUF2324)
KM406_RS24910	COG0739	heme binding
KM406_RS24920	COG3377	Domain of unknown function (DUF1805)
KM406_RS24925	COG0737	Belongs to the 5'-nucleotidase family
KM406_RS24930	COG1695	Transcriptional regulator
KM406_RS24940	COG0719	Fe-S assembly protein
KM406_RS24945	COG0822	iron-sulfur transferase activity
KM406_RS24950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM406_RS24955	COG0719	Fe-S assembly protein
KM406_RS24960	COG0396	ATPase activity
KM406_RS24965	COG1464	Belongs to the NlpA lipoprotein family
KM406_RS24970	COG1464	Belongs to the NlpA lipoprotein family
KM406_RS24975	COG2011	ABC-type metal ion transport system permease component
KM406_RS24980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM406_RS24990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM406_RS24995	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM406_RS25005	COG1393	Belongs to the ArsC family
KM406_RS25050	COG0039	L-malate dehydrogenase activity
KM406_RS25075	COG1309	transcriptional regulator
KM406_RS25080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM406_RS25085	COG1960	acyl-CoA dehydrogenase activity
KM406_RS25090	COG0183	Belongs to the thiolase family
KM406_RS25095	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM406_RS25095	COG1024	Enoyl-CoA hydratase
KM406_RS25105	COG1686	Belongs to the peptidase S11 family
KM406_RS25120	COG0011	TIGRFAM Protein of
KM406_RS25125	COG0840	transmembrane signaling receptor activity
KM406_RS25145	COG2814	Major facilitator Superfamily
KM406_RS25150	COG0531	amino acid
KM406_RS25160	COG0706	membrane insertase activity
KM406_RS25170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM406_RS25205	COG0586	Pfam SNARE associated Golgi protein
KM406_RS25215	COG1376	ErfK ybiS ycfS ynhG family protein
KM406_RS25220	COG0745	RESPONSE REGULATOR receiver
KM406_RS25225	COG5002	protein histidine kinase activity
KM406_RS25250	COG2151	metal-sulfur cluster biosynthetic enzyme
KM406_RS25255	COG3227	Zinc metalloprotease (Elastase)
KM406_RS25260	COG1741	Belongs to the pirin family
KM406_RS25275	COG0475	glutathione-regulated potassium exporter activity
KM406_RS25280	COG0490	domain, Protein
KM406_RS25285	COG1115	amino acid carrier protein
KM406_RS25290	COG0783	Belongs to the Dps family
KM406_RS25305	COG1611	Belongs to the LOG family
KM406_RS25325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS25330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS25335	COG1115	amino acid carrier protein
KM406_RS25340	COG1115	amino acid carrier protein
KM406_RS25345	COG2910	NAD(P)H-binding
KM406_RS25360	COG0656	L-ascorbic acid biosynthetic process
KM406_RS25365	COG2814	Major facilitator Superfamily
KM406_RS25370	COG1733	regulation of RNA biosynthetic process
KM406_RS25380	COG1252	NADH dehydrogenase
KM406_RS25385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM406_RS25390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM406_RS25400	COG3290	protein histidine kinase activity
KM406_RS25400	COG0840	transmembrane signaling receptor activity
KM406_RS25410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM406_RS25415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM406_RS25430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM406_RS25485	COG0557	exoribonuclease II activity
KM406_RS25490	COG1647	Serine aminopeptidase, S33
KM406_RS25495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM406_RS25500	COG1346	cytolysis
KM406_RS25595	COG4695	Portal protein
KM406_RS25620	COG4974	Belongs to the 'phage' integrase family
KM406_RS25630	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM406_RS25635	COG0149	triose-phosphate isomerase activity
KM406_RS25645	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM406_RS25660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM406_RS25685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM406_RS25700	COG2323	membrane
KM406_RS25705	COG0740	serine-type endopeptidase activity
KM406_RS25710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM406_RS25720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM406_RS25730	COG1051	belongs to the nudix hydrolase family
KM406_RS25740	COG0492	ferredoxin-NADP+ reductase activity
KM406_RS25745	COG0457	Tetratricopeptide repeat
KM406_RS25750	COG0110	maltose O-acetyltransferase activity
KM406_RS25770	COG1950	PFAM Membrane protein of
KM406_RS25780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM406_RS25785	COG0556	nucleotide-excision repair
KM406_RS25805	COG0789	Transcriptional regulator
KM406_RS25830	COG2855	membrane
KM406_RS25835	COG0583	DNA-binding transcription factor activity
KM406_RS25845	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM406_RS25850	COG0488	(ABC) transporter
KM406_RS25860	COG1132	(ABC) transporter
KM406_RS25865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM406_RS25870	COG3409	Peptidoglycan-binding domain 1 protein
KM406_RS25870	COG0793	Belongs to the peptidase S41A family
KM406_RS25875	COG2177	Part of the ABC transporter FtsEX involved in
KM406_RS25880	COG2884	Cell division ATP-binding protein ftsE
KM406_RS25895	COG0653	protein targeting
KM406_RS25900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM406_RS25905	COG1278	Cold shock
KM406_RS25910	COG1040	competence protein
KM406_RS25915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM406_RS25920	COG1388	LysM domain
KM406_RS25920	COG0791	NLP P60 protein
KM406_RS25925	COG1733	regulation of RNA biosynthetic process
KM406_RS25930	COG1307	EDD domain protein, DegV family
KM406_RS25935	COG1739	Uncharacterized protein family UPF0029
KM406_RS25940	COG1316	TRANSCRIPTIONal
KM406_RS25945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM406_RS25950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM406_RS25955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM406_RS25965	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM406_RS25965	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM406_RS25980	COG3394	polysaccharide catabolic process
KM406_RS25985	COG1486	melibiose metabolic process
KM406_RS25990	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM406_RS25995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM406_RS26005	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM406_RS26010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM406_RS26015	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM406_RS26025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM406_RS26030	COG1301	dicarboxylic acid transport
KM406_RS26040	COG0346	lactoylglutathione lyase activity
KM406_RS26045	COG1511	domain protein
KM406_RS26050	COG0583	DNA-binding transcription factor activity
KM406_RS26055	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM406_RS26070	COG1271	oxidase subunit
KM406_RS26075	COG1294	oxidase, subunit
KM406_RS26080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM406_RS26090	COG1620	l-lactate permease
KM406_RS26100	COG2389	metal-binding protein
KM406_RS26110	COG1368	sulfuric ester hydrolase activity
KM406_RS26125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM406_RS26135	COG1215	transferase activity, transferring glycosyl groups
KM406_RS26140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM406_RS26145	COG1388	LysM domain
KM406_RS26145	COG3584	3D domain protein
KM406_RS26170	COG4715	Zinc finger, swim domain protein
KM406_RS26175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM406_RS26215	COG0577	efflux transmembrane transporter activity
KM406_RS26220	COG1136	(ABC) transporter
KM406_RS26255	COG5002	protein histidine kinase activity
KM406_RS26260	COG0745	RESPONSE REGULATOR receiver
KM406_RS26265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM406_RS26285	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM406_RS26290	COG1134	teichoic acid transport
KM406_RS26295	COG1682	transport, permease protein
KM406_RS26300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM406_RS26345	COG1609	Transcriptional regulator
KM406_RS26360	COG0739	heme binding
KM406_RS26380	COG2385	sporulation resulting in formation of a cellular spore
KM406_RS26395	COG4836	Membrane
KM406_RS26400	COG1007	ATP synthesis coupled electron transport
KM406_RS26405	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM406_RS26410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM406_RS26420	COG0839	Belongs to the complex I subunit 6 family
KM406_RS26435	COG0649	NAD binding
KM406_RS26440	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM406_RS26455	COG3300	MHYT domain
KM406_RS26455	COG5001	Diguanylate cyclase
KM406_RS26505	COG0356	it plays a direct role in the translocation of protons across the membrane
KM406_RS26540	COG0698	ribose 5-phosphate isomerase
KM406_RS26550	COG2190	(PTS) system
KM406_RS26555	COG2259	Doxx family
KM406_RS26560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM406_RS26575	COG0009	L-threonylcarbamoyladenylate synthase
KM406_RS26590	COG2890	protein-(glutamine-N5) methyltransferase activity
KM406_RS26610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM406_RS26615	COG1494	fructose-1,6-bisphosphatase
KM406_RS26635	COG4821	SIS domain
KM406_RS26645	COG3343	RNA polymerase activity
KM406_RS26655	COG1960	acyl-CoA dehydrogenase activity
KM406_RS26660	COG1960	acyl-CoA dehydrogenase activity
KM406_RS26665	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM406_RS26670	COG0183	Belongs to the thiolase family
KM406_RS26675	COG2181	nitrate reductase activity
KM406_RS26675	COG0247	lactate metabolic process
KM406_RS26680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM406_RS26690	COG5001	Diguanylate cyclase
KM406_RS26690	COG3300	MHYT domain
KM406_RS26710	COG2197	response regulator
KM406_RS26715	COG4585	Histidine kinase
KM406_RS26720	COG0842	Transport permease protein
KM406_RS26725	COG1131	(ABC) transporter
KM406_RS26730	COG0024	Methionine aminopeptidase
KM406_RS26740	COG2234	aminopeptidase activity
KM406_RS26760	COG1595	DNA-templated transcription, initiation
KM406_RS26765	COG0018	arginyl-trna synthetase
KM406_RS26770	COG4506	Protein conserved in bacteria
KM406_RS26775	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM406_RS26790	COG0010	Belongs to the arginase family
KM406_RS26800	COG2814	Major facilitator Superfamily
KM406_RS26805	COG0789	Transcriptional regulator
KM406_RS26810	COG0584	glycerophosphoryl diester phosphodiesterase
KM406_RS26815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM406_RS26825	COG1994	Peptidase M50
KM406_RS26835	COG1078	dGTPase activity
KM406_RS26840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM406_RS26845	COG1120	ATPase activity
KM406_RS26850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM406_RS26875	COG0095	Lipoate-protein ligase
KM406_RS26880	COG0280	phosphate acetyltransferase
KM406_RS26895	COG3773	Cell wall hydrolase
KM406_RS26905	COG2363	Small membrane protein
KM406_RS26915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM406_RS26920	COG2233	PERMEase
KM406_RS26925	COG0561	phosphatase activity
KM406_RS26930	COG2814	Major facilitator Superfamily
KM406_RS26940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM406_RS26945	COG1131	(ABC) transporter
KM406_RS26950	COG2755	lipolytic protein G-D-S-L family
KM406_RS26955	COG1609	Transcriptional regulator
KM406_RS26965	COG0460	homoserine dehydrogenase
KM406_RS26975	COG2873	o-acetylhomoserine
KM406_RS26985	COG1011	Hydrolase
KM406_RS26990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM406_RS27000	COG2197	response regulator
KM406_RS27010	COG0351	phosphomethylpyrimidine kinase
KM406_RS27015	COG3706	GGDEF domain
KM406_RS27020	COG2879	small protein
KM406_RS27025	COG1966	Carbon starvation protein
KM406_RS27030	COG3279	Response regulator of the LytR AlgR family
KM406_RS27035	COG0477	Major facilitator Superfamily
KM406_RS27060	COG0840	transmembrane signaling receptor activity
KM406_RS27070	COG1607	acyl-coa hydrolase
KM406_RS27085	COG0488	(ABC) transporter
KM406_RS27105	COG0463	Glycosyl transferase, family 2
KM406_RS27110	COG1309	transcriptional regulator
KM406_RS27115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM406_RS27120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM406_RS27120	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM406_RS27125	COG0628	permease
KM406_RS27140	COG3279	Response regulator of the LytR AlgR family
KM406_RS27145	COG3275	phosphorelay sensor kinase activity
KM406_RS27150	COG2814	Major facilitator Superfamily
KM406_RS27155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM406_RS27160	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM406_RS27165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM406_RS27185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM406_RS27190	COG1272	protein, Hemolysin III
KM406_RS27210	COG0516	GMP reductase activity
KM406_RS27215	COG1164	Oligoendopeptidase f
KM406_RS27235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM406_RS27240	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM406_RS27245	COG4853	Protein conserved in bacteria
KM406_RS27250	COG4863	YycH protein
KM406_RS27255	COG5002	protein histidine kinase activity
KM406_RS27260	COG0745	RESPONSE REGULATOR receiver
KM406_RS27290	COG0305	Participates in initiation and elongation during chromosome replication
KM406_RS27300	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM406_RS27305	COG4241	membrane
KM406_RS27315	COG0629	single-stranded DNA binding
KM406_RS27325	COG0012	GTP binding
KM406_RS27330	COG4481	Protein conserved in bacteria
KM406_RS27335	COG0668	transmembrane transport
KM406_RS27345	COG1475	DNA binding
KM406_RS27350	COG1192	Involved in chromosome partitioning
KM406_RS27375	COG1847	R3H domain protein
KM406_RS27380	COG0706	membrane insertase activity
KM406_RS27390	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM406_RS27445	COG3344	reverse transcriptase
KM406_RS27525	COG3344	reverse transcriptase
KM406_RS27730	COG4962	Type ii secretion system protein e
KM406_RS27865	COG2311	Membrane
KM406_RS27885	COG4196	transglutaminase domain protein
KM406_RS27890	COG0671	phosphoesterase, PA-phosphatase related
KM406_RS27910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM406_RS27915	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM406_RS28085	COG2002	toxin-antitoxin pair type II binding
KM406_RS28095	COG4974	Belongs to the 'phage' integrase family
KM406_RS28155	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM406_RS28165	COG4974	Belongs to the 'phage' integrase family
KM406_RS28190	COG0457	Tetratricopeptide repeat
KM406_RS28395	COG0791	NLP P60 protein
KM406_RS28395	COG0741	lytic transglycosylase activity
KM406_RS28515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM406_RS28525	COG4166	transmembrane transport
KM406_RS28570	COG1280	lysine exporter protein (LysE YggA)
KM406_RS28595	COG0681	Belongs to the peptidase S26 family
KM406_RS28670	COG1309	transcriptional regulator
KM406_RS28675	COG1683	Conserved Protein
KM406_RS28720	COG1192	Involved in chromosome partitioning