locus-tag	class	description
KM401_RS00010	COG0592	DNA-directed DNA polymerase activity
KM401_RS00015	COG2501	S4 domain
KM401_RS00025	COG0187	DNA topoisomerase II activity
KM401_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM401_RS00065	COG0516	GMP reductase activity
KM401_RS00065	COG0517	IMP dehydrogenase activity
KM401_RS00070	COG1686	Belongs to the peptidase S11 family
KM401_RS00100	COG1428	Deoxynucleoside kinase
KM401_RS00105	COG1428	Deoxynucleoside kinase
KM401_RS00110	COG1335	isochorismatase
KM401_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM401_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM401_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM401_RS00190	COG0470	DNA polymerase III
KM401_RS00195	COG1774	PSP1 C-terminal conserved region
KM401_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM401_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM401_RS00220	COG2002	toxin-antitoxin pair type II binding
KM401_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_RS00230	COG0084	hydrolase, TatD family'
KM401_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM401_RS00250	COG4466	Protein conserved in bacteria
KM401_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM401_RS00270	COG0251	oxidation-reduction process
KM401_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM401_RS00305	COG2002	toxin-antitoxin pair type II binding
KM401_RS00310	COG2244	polysaccharide biosynthetic process
KM401_RS00315	COG3956	TIGRFAM MazG family protein
KM401_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM401_RS00340	COG1098	S1 RNA binding domain
KM401_RS00355	COG2208	phosphoserine phosphatase activity
KM401_RS00360	COG0037	tRNA processing
KM401_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM401_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM401_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM401_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM401_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM401_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM401_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM401_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM401_RS00420	COG1396	sequence-specific DNA binding
KM401_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM401_RS00455	COG3880	PFAM UvrB UvrC protein
KM401_RS00465	COG0542	response to heat
KM401_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM401_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM401_RS00500	COG1045	serine acetyltransferase
KM401_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM401_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM401_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM401_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM401_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM401_RS00565	COG2813	Specifically methylates the guanine in position
KM401_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM401_RS00580	COG1358	cellular component organization or biogenesis
KM401_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM401_RS00710	COG0201	protein transport
KM401_RS00720	COG0024	Methionine aminopeptidase
KM401_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM401_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM401_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_RS00795	COG0489	protein tyrosine kinase activity
KM401_RS00805	COG2194	sulfuric ester hydrolase activity
KM401_RS00810	COG0726	polysaccharide deacetylase
KM401_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM401_RS00895	COG4856	YbbR-like protein
KM401_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM401_RS00915	COG0596	Alpha beta hydrolase
KM401_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM401_RS00940	COG4946	Tricorn protease homolog
KM401_RS00940	COG1506	peptidase
KM401_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM401_RS00975	COG2011	ABC-type metal ion transport system permease component
KM401_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM401_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM401_RS00990	COG0604	alcohol dehydrogenase
KM401_RS01000	COG0277	FAD linked oxidase domain protein
KM401_RS01005	COG2271	Major facilitator Superfamily
KM401_RS01015	COG2814	Major facilitator Superfamily
KM401_RS01030	COG0601	transmembrane transport
KM401_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM401_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM401_RS01050	COG4166	transmembrane transport
KM401_RS01060	COG2207	Transcriptional regulator
KM401_RS01075	COG4166	transmembrane transport
KM401_RS01080	COG4166	transmembrane transport
KM401_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM401_RS01105	COG4149	molybdate abc transporter
KM401_RS01115	COG1910	domain protein
KM401_RS01125	COG0583	DNA-binding transcription factor activity
KM401_RS01130	COG0697	spore germination
KM401_RS01145	COG0204	Acyl-transferase
KM401_RS01155	COG1609	Transcriptional regulator
KM401_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS01175	COG0084	hydrolase, TatD family'
KM401_RS01180	COG5298	Protein conserved in bacteria
KM401_RS01205	COG0488	(ABC) transporter
KM401_RS01220	COG0747	negative chemotaxis
KM401_RS01225	COG0601	transmembrane transport
KM401_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM401_RS01240	COG4608	Belongs to the ABC transporter superfamily
KM401_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM401_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM401_RS01290	COG2814	Major facilitator Superfamily
KM401_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM401_RS01310	COG4294	response to UV
KM401_RS01315	COG0457	Tetratricopeptide repeat
KM401_RS01315	COG0705	Rhomboid family
KM401_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM401_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM401_RS01335	COG0864	Transcriptional regulator
KM401_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM401_RS01345	COG2183	response to ionizing radiation
KM401_RS01440	COG0802	atpase or kinase
KM401_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
KM401_RS01450	COG0456	acetyltransferase
KM401_RS01460	COG0488	(ABC) transporter
KM401_RS01475	COG1266	CAAX protease self-immunity
KM401_RS01495	COG2252	PERMEase
KM401_RS01505	COG5002	protein histidine kinase activity
KM401_RS01535	COG2226	methyltransferase
KM401_RS01580	COG1968	undecaprenyl-diphosphatase activity
KM401_RS01595	COG2205	protein histidine kinase activity
KM401_RS01600	COG0745	RESPONSE REGULATOR receiver
KM401_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM401_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM401_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM401_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM401_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM401_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM401_RS01680	COG0151	Belongs to the GarS family
KM401_RS01705	COG0210	DNA helicase
KM401_RS01715	COG4851	CamS sex pheromone cAM373 precursor
KM401_RS01735	COG1335	isochorismatase
KM401_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM401_RS01745	COG2011	ABC-type metal ion transport system permease component
KM401_RS01750	COG1464	Belongs to the NlpA lipoprotein family
KM401_RS01775	COG1846	Transcriptional regulator
KM401_RS01800	COG1597	lipid kinase activity
KM401_RS01805	COG0546	phosphoglycolate phosphatase activity
KM401_RS01810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM401_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS01825	COG2076	Multidrug Resistance protein
KM401_RS01830	COG2309	aminopeptidase activity
KM401_RS01845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS01850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM401_RS01855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM401_RS01865	COG4807	Protein conserved in bacteria
KM401_RS01890	COG1757	Na H antiporter
KM401_RS01895	COG1473	amidohydrolase
KM401_RS01910	COG0450	alkyl hydroperoxide reductase
KM401_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS01935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS01940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_RS01955	COG0166	Belongs to the GPI family
KM401_RS01990	COG5002	protein histidine kinase activity
KM401_RS02010	COG3541	Predicted nucleotidyltransferase
KM401_RS02015	COG2814	Major facilitator Superfamily
KM401_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
KM401_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_RS02030	COG0765	amino acid transport
KM401_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_RS02045	COG0840	transmembrane signaling receptor activity
KM401_RS02050	COG0840	transmembrane signaling receptor activity
KM401_RS02055	COG0366	Alpha amylase catalytic
KM401_RS02060	COG1263	PTS System
KM401_RS02060	COG2190	(PTS) system
KM401_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_RS02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM401_RS02105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_RS02115	COG1116	anion transmembrane transporter activity
KM401_RS02120	COG0488	(ABC) transporter
KM401_RS02165	COG2270	Major facilitator Superfamily
KM401_RS02180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM401_RS02195	COG2310	stress, protein
KM401_RS02200	COG2310	stress, protein
KM401_RS02205	COG2310	stress, protein
KM401_RS02210	COG0861	Integral membrane protein TerC family
KM401_RS02220	COG3853	Toxic anion resistance protein (TelA)
KM401_RS02235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM401_RS02245	COG1295	ribonuclease BN
KM401_RS02250	COG2217	Heavy metal translocating P-type atpase
KM401_RS02255	COG0697	spore germination
KM401_RS02275	COG0586	Pfam SNARE associated Golgi protein
KM401_RS02290	COG3871	stress protein (general stress protein 26)
KM401_RS02295	COG0387	Pfam Sodium calcium exchanger
KM401_RS02305	COG0535	radical SAM domain protein
KM401_RS02330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM401_RS02335	COG0582	viral genome integration into host DNA
KM401_RS02345	COG1396	sequence-specific DNA binding
KM401_RS02360	COG1396	sequence-specific DNA binding
KM401_RS02395	COG1484	DNA-dependent DNA replication
KM401_RS02625	COG0101	tRNA pseudouridine synthase activity
KM401_RS02635	COG3829	transcription factor binding
KM401_RS02645	COG0833	amino acid
KM401_RS02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM401_RS02680	COG1263	PTS System
KM401_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_RS02700	COG0463	Glycosyl transferase, family 2
KM401_RS02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM401_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM401_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM401_RS02745	COG1228	amidohydrolase
KM401_RS02750	COG1090	epimerase
KM401_RS02780	COG1988	membrane-bound metal-dependent
KM401_RS02785	COG1194	a g-specific adenine glycosylase
KM401_RS02810	COG1132	(ABC) transporter
KM401_RS02815	COG4129	membrane
KM401_RS02820	COG0067	glutamate synthase
KM401_RS02820	COG0069	glutamate synthase activity
KM401_RS02820	COG0070	glutamate synthase
KM401_RS02830	COG4555	ABC transporter
KM401_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM401_RS02855	COG0735	belongs to the Fur family
KM401_RS02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM401_RS02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM401_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM401_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM401_RS03005	COG2766	serine protein kinase
KM401_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM401_RS03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM401_RS03040	COG2268	Band 7 protein
KM401_RS03050	COG3290	protein histidine kinase activity
KM401_RS03055	COG4565	transcriptional regulatory protein
KM401_RS03060	COG2851	Citrate transporter
KM401_RS03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM401_RS03085	COG3842	ATPase activity
KM401_RS03090	COG1175	transmembrane transport
KM401_RS03095	COG0395	ABC-type sugar transport system, permease component
KM401_RS03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM401_RS03110	COG0745	RESPONSE REGULATOR receiver
KM401_RS03115	COG5002	protein histidine kinase activity
KM401_RS03125	COG4990	cell redox homeostasis
KM401_RS03135	COG3290	protein histidine kinase activity
KM401_RS03140	COG4565	transcriptional regulatory protein
KM401_RS03145	COG3493	citrate carrier protein
KM401_RS03150	COG0281	malic enzyme
KM401_RS03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_RS03175	COG5002	protein histidine kinase activity
KM401_RS03180	COG0745	RESPONSE REGULATOR receiver
KM401_RS03185	COG0456	acetyltransferase
KM401_RS03185	COG0454	-acetyltransferase
KM401_RS03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM401_RS03195	COG3383	formate dehydrogenase (NAD+) activity
KM401_RS03215	COG0531	amino acid
KM401_RS03220	COG0640	Transcriptional regulator
KM401_RS03225	COG2217	Heavy metal translocating P-type atpase
KM401_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM401_RS03245	COG3227	Zinc metalloprotease (Elastase)
KM401_RS03265	COG2720	vancomycin resistance protein
KM401_RS03270	COG1316	TRANSCRIPTIONal
KM401_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS03280	COG0346	lactoylglutathione lyase activity
KM401_RS03290	COG1027	Aspartate ammonia-lyase
KM401_RS03295	COG1620	l-lactate permease
KM401_RS03310	COG3104	oligopeptide transport
KM401_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS03335	COG2226	methyltransferase
KM401_RS03340	COG0156	8-amino-7-oxononanoate synthase activity
KM401_RS03360	COG0714	Associated with various cellular activities
KM401_RS03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_RS03385	COG0531	amino acid
KM401_RS03390	COG2188	Transcriptional regulator
KM401_RS03395	COG1263	PTS System
KM401_RS03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_RS03400	COG0366	Alpha amylase catalytic
KM401_RS03415	COG0697	spore germination
KM401_RS03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM401_RS03430	COG1115	amino acid carrier protein
KM401_RS03435	COG1126	abc transporter atp-binding protein
KM401_RS03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_RS03445	COG0765	amino acid transport
KM401_RS03450	COG0765	amino acid transport
KM401_RS03455	COG0833	amino acid
KM401_RS03480	COG2378	regulation of single-species biofilm formation
KM401_RS03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM401_RS03490	COG5002	protein histidine kinase activity
KM401_RS03505	COG0659	secondary active sulfate transmembrane transporter activity
KM401_RS03520	COG0747	negative chemotaxis
KM401_RS03530	COG0601	transmembrane transport
KM401_RS03535	COG4608	Belongs to the ABC transporter superfamily
KM401_RS03545	COG2271	Major facilitator Superfamily
KM401_RS03550	COG1846	Transcriptional regulator
KM401_RS03560	COG1609	Transcriptional regulator
KM401_RS03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM401_RS03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM401_RS03585	COG1879	ABC-type sugar transport system periplasmic component
KM401_RS03610	COG1063	alcohol dehydrogenase
KM401_RS03625	COG3568	Endonuclease Exonuclease Phosphatase
KM401_RS03650	COG1968	undecaprenyl-diphosphatase activity
KM401_RS03655	COG0840	transmembrane signaling receptor activity
KM401_RS03660	COG1388	LysM domain
KM401_RS03660	COG3584	3D domain protein
KM401_RS03665	COG1476	TRANSCRIPTIONal
KM401_RS03680	COG3104	oligopeptide transport
KM401_RS03685	COG1114	Component of the transport system for branched-chain amino acids
KM401_RS03700	COG1113	amino acid transport
KM401_RS03705	COG2252	PERMEase
KM401_RS03730	COG0569	domain protein
KM401_RS03730	COG0475	glutathione-regulated potassium exporter activity
KM401_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM401_RS03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM401_RS03755	COG4990	cell redox homeostasis
KM401_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_RS03775	COG0697	spore germination
KM401_RS03780	COG0531	amino acid
KM401_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM401_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM401_RS03800	COG1918	ferrous iron import across plasma membrane
KM401_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM401_RS03805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM401_RS03810	COG0573	inorganic phosphate transmembrane transporter activity
KM401_RS03815	COG0581	inorganic phosphate transmembrane transporter activity
KM401_RS03945	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM401_RS03965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM401_RS03970	COG1116	anion transmembrane transporter activity
KM401_RS03975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_RS03980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM401_RS03985	COG0352	thiamine-phosphate diphosphorylase activity
KM401_RS03990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_RS03995	COG2104	thiamine diphosphate biosynthetic process
KM401_RS04005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_RS04010	COG0351	phosphomethylpyrimidine kinase
KM401_RS04050	COG2205	protein histidine kinase activity
KM401_RS04055	COG2814	Major facilitator Superfamily
KM401_RS04060	COG1846	Transcriptional regulator
KM401_RS04075	COG2252	PERMEase
KM401_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM401_RS04100	COG1621	beta-fructofuranosidase activity
KM401_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_RS04105	COG1263	PTS System
KM401_RS04110	COG1609	Transcriptional regulator
KM401_RS04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_RS04125	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM401_RS04160	COG0778	Nitroreductase
KM401_RS04165	COG2719	SpoVR family
KM401_RS04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM401_RS04195	COG1937	Protein conserved in bacteria
KM401_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
KM401_RS04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
KM401_RS04225	COG2210	Belongs to the sulfur carrier protein TusA family
KM401_RS04230	COG0730	response to heat
KM401_RS04240	COG1316	TRANSCRIPTIONal
KM401_RS04245	COG0604	alcohol dehydrogenase
KM401_RS04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM401_RS04265	COG3711	transcriptional antiterminator
KM401_RS04265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM401_RS04270	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM401_RS04275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM401_RS04295	COG3584	3D domain protein
KM401_RS04295	COG1388	LysM domain
KM401_RS04300	COG0577	efflux transmembrane transporter activity
KM401_RS04305	COG1136	(ABC) transporter
KM401_RS04315	COG5522	Integral membrane protein (intg_mem_TP0381)
KM401_RS04330	COG1114	Component of the transport system for branched-chain amino acids
KM401_RS04335	COG3546	catalase activity
KM401_RS04370	COG0586	Pfam SNARE associated Golgi protein
KM401_RS04405	COG0531	amino acid
KM401_RS04410	COG0475	glutathione-regulated potassium exporter activity
KM401_RS04420	COG1737	Transcriptional regulator
KM401_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_RS04430	COG1263	PTS System
KM401_RS04440	COG2259	Doxx family
KM401_RS04455	COG0697	spore germination
KM401_RS04460	COG1522	sequence-specific DNA binding
KM401_RS04475	COG2076	Multidrug Resistance protein
KM401_RS04480	COG1309	transcriptional regulator
KM401_RS04485	COG2814	Major facilitator Superfamily
KM401_RS04490	COG1733	regulation of RNA biosynthetic process
KM401_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM401_RS04505	COG4533	DNA binding
KM401_RS04510	COG2211	Major facilitator Superfamily
KM401_RS04520	COG0693	protein deglycase activity
KM401_RS04525	COG0753	catalase activity
KM401_RS04525	COG0693	protein deglycase activity
KM401_RS04535	COG0531	amino acid
KM401_RS04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM401_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS04555	COG1132	(ABC) transporter
KM401_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_RS04570	COG0765	amino acid transport
KM401_RS04575	COG1126	abc transporter atp-binding protein
KM401_RS04590	COG0189	ligase activity
KM401_RS04620	COG0028	Belongs to the TPP enzyme family
KM401_RS04625	COG3527	Alpha-acetolactate decarboxylase
KM401_RS04640	COG0561	phosphatase activity
KM401_RS04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM401_RS04670	COG0659	secondary active sulfate transmembrane transporter activity
KM401_RS04690	COG0653	protein targeting
KM401_RS04695	COG2244	polysaccharide biosynthetic process
KM401_RS04705	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_RS04710	COG4196	transglutaminase domain protein
KM401_RS04725	COG1696	Membrane protein involved in D-alanine export
KM401_RS04740	COG1024	Enoyl-CoA hydratase
KM401_RS04760	COG1363	Peptidase, m42
KM401_RS04780	COG3938	Belongs to the proline racemase family
KM401_RS04820	COG0601	transmembrane transport
KM401_RS04825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_RS04835	COG4608	Belongs to the ABC transporter superfamily
KM401_RS04870	COG0477	Major facilitator Superfamily
KM401_RS04875	COG3290	protein histidine kinase activity
KM401_RS04880	COG4565	transcriptional regulatory protein
KM401_RS04885	COG3181	Tripartite tricarboxylate transporter family receptor
KM401_RS04915	COG0789	Transcriptional regulator
KM401_RS04915	COG4978	Transcriptional regulator
KM401_RS04930	COG0305	Participates in initiation and elongation during chromosome replication
KM401_RS04970	COG0477	Major facilitator Superfamily
KM401_RS05015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM401_RS05015	COG3320	Male sterility
KM401_RS05020	COG1309	transcriptional regulator
KM401_RS05040	COG1183	phosphatidylcholine synthase activity
KM401_RS05060	COG2376	Dihydroxyacetone kinase
KM401_RS05070	COG2376	Dihydroxyacetone kinase
KM401_RS05075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM401_RS05080	COG1959	2 iron, 2 sulfur cluster binding
KM401_RS05110	COG2770	Histidine kinase
KM401_RS05110	COG3437	response regulator, receiver
KM401_RS05165	COG3237	CsbD-like
KM401_RS05190	COG1191	sigma factor activity
KM401_RS05200	COG2208	phosphoserine phosphatase activity
KM401_RS05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM401_RS05210	COG0784	Response regulator, receiver
KM401_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_RS05210	COG2198	Histidine kinase
KM401_RS05210	COG2205	protein histidine kinase activity
KM401_RS05265	COG0420	3'-5' exonuclease activity
KM401_RS05290	COG1309	transcriptional regulator
KM401_RS05295	COG2814	Major facilitator Superfamily
KM401_RS05300	COG0346	lactoylglutathione lyase activity
KM401_RS05310	COG0457	Tetratricopeptide repeat
KM401_RS05315	COG2267	carboxylic ester hydrolase activity
KM401_RS05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM401_RS05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM401_RS05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM401_RS05390	COG0477	Major facilitator Superfamily
KM401_RS05395	COG0477	Major facilitator Superfamily
KM401_RS05405	COG3973	AAA domain
KM401_RS05410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM401_RS05430	COG4980	gas vesicle protein
KM401_RS05435	COG0537	adenosine 5'-monophosphoramidase activity
KM401_RS05440	COG1131	(ABC) transporter
KM401_RS05445	COG4473	ABC transporter
KM401_RS05460	COG1309	transcriptional regulator
KM401_RS05470	COG3402	PFAM membrane-flanked domain
KM401_RS05515	COG3402	PFAM membrane-flanked domain
KM401_RS05520	COG3428	Bacterial PH domain
KM401_RS05525	COG2329	Antibiotic biosynthesis monooxygenase
KM401_RS05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_RS05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM401_RS05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM401_RS05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM401_RS05580	COG1309	transcriptional regulator
KM401_RS05585	COG1511	domain protein
KM401_RS05610	COG1609	Transcriptional regulator
KM401_RS05620	COG1234	tRNA 3'-trailer cleavage
KM401_RS05625	COG0095	Lipoate-protein ligase
KM401_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_RS05665	COG3209	COG3209 Rhs family protein
KM401_RS05705	COG1078	dGTPase activity
KM401_RS05715	COG1595	DNA-templated transcription, initiation
KM401_RS05720	COG2207	Transcriptional regulator
KM401_RS05720	COG3708	Transcriptional regulator
KM401_RS05735	COG2205	protein histidine kinase activity
KM401_RS05740	COG0745	RESPONSE REGULATOR receiver
KM401_RS05765	COG0501	Belongs to the peptidase M48B family
KM401_RS05770	COG0840	transmembrane signaling receptor activity
KM401_RS05775	COG0697	spore germination
KM401_RS05795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM401_RS05800	COG2224	Isocitrate lyase
KM401_RS05825	COG4903	ComK protein
KM401_RS05830	COG0398	Pfam SNARE associated Golgi protein
KM401_RS05840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM401_RS05845	COG1074	ATP-dependent DNA helicase activity
KM401_RS05890	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM401_RS05915	COG0367	asparagine synthase
KM401_RS05920	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM401_RS05925	COG0753	catalase activity
KM401_RS05930	COG0004	ammonium transporteR
KM401_RS05950	COG2996	Protein conserved in bacteria
KM401_RS05960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM401_RS05970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS05985	COG0561	phosphatase activity
KM401_RS05995	COG0542	response to heat
KM401_RS06005	COG2267	carboxylic ester hydrolase activity
KM401_RS06020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_RS06025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM401_RS06030	COG5504	Zn-dependent protease
KM401_RS06040	COG0180	Tryptophanyl-tRNA synthetase
KM401_RS06050	COG4166	transmembrane transport
KM401_RS06055	COG0601	transmembrane transport
KM401_RS06060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_RS06065	COG0444	Belongs to the ABC transporter superfamily
KM401_RS06070	COG4608	Belongs to the ABC transporter superfamily
KM401_RS06075	COG0534	Mate efflux family protein
KM401_RS06080	COG4166	transmembrane transport
KM401_RS06095	COG0861	Integral membrane protein TerC family
KM401_RS06100	COG4862	establishment of competence for transformation
KM401_RS06105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_RS06115	COG1164	Oligoendopeptidase f
KM401_RS06125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM401_RS06130	COG2346	COG2346, Truncated hemoglobins
KM401_RS06135	COG4116	CYTH
KM401_RS06145	COG2357	RelA SpoT domain protein
KM401_RS06155	COG0564	pseudouridine synthase activity
KM401_RS06175	COG1216	Glycosyl transferase, family 2
KM401_RS06175	COG0463	Glycosyl transferase, family 2
KM401_RS06195	COG0463	Glycosyl transferase, family 2
KM401_RS06195	COG0457	Tetratricopeptide repeat
KM401_RS06215	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM401_RS06230	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM401_RS06275	COG2153	protein acetylation
KM401_RS06285	COG2382	esterase
KM401_RS06300	COG5492	domain, Protein
KM401_RS06305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_RS06315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM401_RS06315	COG0512	Glutamine amidotransferase of anthranilate synthase
KM401_RS06350	COG1620	l-lactate permease
KM401_RS06355	COG5634	Uncharacterized conserved protein (DUF2278)
KM401_RS06410	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_RS06420	COG1476	TRANSCRIPTIONal
KM401_RS06480	COG2226	methyltransferase
KM401_RS06490	COG1686	Belongs to the peptidase S11 family
KM401_RS06495	COG0681	Belongs to the peptidase S26 family
KM401_RS06530	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS06535	COG3842	ATPase activity
KM401_RS06540	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM401_RS06545	COG1177	transmembrane transport
KM401_RS06550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM401_RS06560	COG2409	Drug exporters of the RND superfamily
KM401_RS06570	COG0564	pseudouridine synthase activity
KM401_RS06580	COG2340	Cysteine-rich secretory protein family
KM401_RS06585	COG0247	lactate metabolic process
KM401_RS06590	COG0277	FAD linked oxidase domain protein
KM401_RS06595	COG3835	regulator
KM401_RS06605	COG0745	RESPONSE REGULATOR receiver
KM401_RS06610	COG5002	protein histidine kinase activity
KM401_RS06615	COG2186	Transcriptional regulator
KM401_RS06635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM401_RS06645	COG2116	formate transmembrane transporter activity
KM401_RS06650	COG0861	Integral membrane protein TerC family
KM401_RS06655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM401_RS06665	COG2030	dehydratase
KM401_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS06690	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM401_RS06695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_RS06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM401_RS06715	COG1840	ABC-type Fe3 transport system, periplasmic component
KM401_RS06745	COG1349	DNA-binding transcription factor activity
KM401_RS06765	COG2861	carbohydrate metabolic process
KM401_RS06775	COG3852	Histidine kinase
KM401_RS06780	COG1846	Transcriptional regulator
KM401_RS06790	COG2318	DinB family
KM401_RS06800	COG5002	protein histidine kinase activity
KM401_RS06810	COG0720	synthase
KM401_RS06825	COG4873	Protein conserved in bacteria
KM401_RS06855	COG1780	Probably involved in ribonucleotide reductase function
KM401_RS06875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM401_RS06880	COG1725	Transcriptional regulator
KM401_RS06885	COG1131	(ABC) transporter
KM401_RS06895	COG1131	(ABC) transporter
KM401_RS06900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM401_RS06915	COG1522	sequence-specific DNA binding
KM401_RS06925	COG1335	isochorismatase
KM401_RS06935	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM401_RS06940	COG2070	2-Nitropropane dioxygenase
KM401_RS06945	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM401_RS06955	COG1696	Membrane protein involved in D-alanine export
KM401_RS06975	COG0716	FMN binding
KM401_RS06990	COG3173	Aminoglycoside phosphotransferase
KM401_RS07010	COG0534	Mate efflux family protein
KM401_RS07015	COG1968	undecaprenyl-diphosphatase activity
KM401_RS07030	COG1846	Transcriptional regulator
KM401_RS07040	COG1301	dicarboxylic acid transport
KM401_RS07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM401_RS07050	COG4709	membrane
KM401_RS07055	COG3874	Sporulation protein YtfJ
KM401_RS07080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_RS07085	COG0028	Belongs to the TPP enzyme family
KM401_RS07090	COG0440	acetolactate synthase activity
KM401_RS07095	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM401_RS07105	COG0473	3-isopropylmalate dehydrogenase activity
KM401_RS07130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM401_RS07165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM401_RS07180	COG1183	phosphatidylcholine synthase activity
KM401_RS07185	COG1368	sulfuric ester hydrolase activity
KM401_RS07195	COG0019	diaminopimelate decarboxylase activity
KM401_RS07215	COG0529	Catalyzes the synthesis of activated sulfate
KM401_RS07220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM401_RS07240	COG1648	precorrin-2 dehydrogenase activity
KM401_RS07245	COG0733	neurotransmitter:sodium symporter activity
KM401_RS07265	COG1757	Na H antiporter
KM401_RS07280	COG4758	membrane
KM401_RS07285	COG4585	Histidine kinase
KM401_RS07290	COG2197	response regulator
KM401_RS07300	COG1114	Component of the transport system for branched-chain amino acids
KM401_RS07310	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM401_RS07335	COG1017	nitric oxide dioxygenase activity
KM401_RS07335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM401_RS07350	COG0730	response to heat
KM401_RS07355	COG0306	phosphate transporter
KM401_RS07360	COG1392	Phosphate transport regulator
KM401_RS07365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_RS07380	COG3852	Histidine kinase
KM401_RS07385	COG1801	Protein of unknown function DUF72
KM401_RS07395	COG0582	viral genome integration into host DNA
KM401_RS07420	COG0392	lysyltransferase activity
KM401_RS07420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM401_RS07435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM401_RS07440	COG1686	Belongs to the peptidase S11 family
KM401_RS07445	COG2715	membrane protein required for spore maturation
KM401_RS07450	COG0700	Nucleoside recognition
KM401_RS07455	COG1187	pseudouridine synthase activity
KM401_RS07465	COG1333	cytochrome c biogenesis protein
KM401_RS07470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM401_RS07475	COG0745	RESPONSE REGULATOR receiver
KM401_RS07480	COG5002	protein histidine kinase activity
KM401_RS07485	COG2096	Adenosyltransferase
KM401_RS07500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM401_RS07505	COG1141	Ferredoxin
KM401_RS07510	COG4955	Helix-turn-helix domain
KM401_RS07515	COG0514	ATP-dependent DNA helicase (RecQ)
KM401_RS07520	COG1266	CAAX protease self-immunity
KM401_RS07540	COG4862	establishment of competence for transformation
KM401_RS07545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM401_RS07565	COG0492	ferredoxin-NADP+ reductase activity
KM401_RS07570	COG0252	asparaginase activity
KM401_RS07640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM401_RS07655	COG0142	geranyltranstransferase activity
KM401_RS07665	COG0142	geranyltranstransferase activity
KM401_RS07685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM401_RS07690	COG0457	Tetratricopeptide repeat
KM401_RS07710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM401_RS07720	COG4347	Protein of unknown function (DUF1405)
KM401_RS07735	COG2738	Putative neutral zinc metallopeptidase
KM401_RS07745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS07750	COG1694	Mazg nucleotide pyrophosphohydrolase
KM401_RS07765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM401_RS07770	COG0438	transferase activity, transferring glycosyl groups
KM401_RS07805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM401_RS07805	COG1199	ATP-dependent helicase activity
KM401_RS07825	COG3935	DnaD domain protein
KM401_RS07830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM401_RS07900	COG0116	Belongs to the methyltransferase superfamily
KM401_RS07910	COG1199	ATP-dependent helicase activity
KM401_RS07915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM401_RS07925	COG3173	Aminoglycoside phosphotransferase
KM401_RS07930	COG0024	Methionine aminopeptidase
KM401_RS07940	COG2233	PERMEase
KM401_RS07945	COG2311	Membrane
KM401_RS07950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM401_RS07960	COG0456	acetyltransferase
KM401_RS08010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM401_RS08035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM401_RS08050	COG1215	transferase activity, transferring glycosyl groups
KM401_RS08055	COG0438	transferase activity, transferring glycosyl groups
KM401_RS08070	COG0454	-acetyltransferase
KM401_RS08090	COG0328	RNA-DNA hybrid ribonuclease activity
KM401_RS08130	COG1280	lysine exporter protein (LysE YggA)
KM401_RS08145	COG3162	membrane
KM401_RS08150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_RS08155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM401_RS08165	COG0475	glutathione-regulated potassium exporter activity
KM401_RS08170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM401_RS08175	COG0789	Transcriptional regulator
KM401_RS08175	COG4978	Transcriptional regulator
KM401_RS08185	COG2323	membrane
KM401_RS08190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM401_RS08245	COG1923	regulation of RNA biosynthetic process
KM401_RS08255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM401_RS08260	COG1360	Flagellar Motor Protein
KM401_RS08265	COG2201	protein-glutamate methylesterase activity
KM401_RS08275	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM401_RS08275	COG1776	CheC inhibitor of MCP methylation
KM401_RS08290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM401_RS08310	COG1256	bacterial-type flagellum assembly
KM401_RS08335	COG1815	bacterial-type flagellum-dependent cell motility
KM401_RS08340	COG1558	bacterial-type flagellum-dependent cell motility
KM401_RS08355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM401_RS08365	COG1157	protein secretion by the type III secretion system
KM401_RS08400	COG0835	chemotaxis
KM401_RS08400	COG0784	Response regulator, receiver
KM401_RS08410	COG0463	Glycosyl transferase, family 2
KM401_RS08435	COG0457	Tetratricopeptide repeat
KM401_RS08435	COG0463	Glycosyl transferase, family 2
KM401_RS08450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM401_RS08455	COG0741	lytic transglycosylase activity
KM401_RS08470	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM401_RS08470	COG1776	CheC inhibitor of MCP methylation
KM401_RS08480	COG1338	Plays a role in the flagellum-specific transport system
KM401_RS08485	COG1987	bacterial-type flagellum assembly
KM401_RS08495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM401_RS08500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM401_RS08505	COG1419	protein localization to endoplasmic reticulum
KM401_RS08510	COG4786	Flagellar basal body rod
KM401_RS08515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM401_RS08540	COG1309	transcriptional regulator
KM401_RS08560	COG2329	Antibiotic biosynthesis monooxygenase
KM401_RS08585	COG0583	DNA-binding transcription factor activity
KM401_RS08595	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM401_RS08605	COG1234	tRNA 3'-trailer cleavage
KM401_RS08630	COG1686	Belongs to the peptidase S11 family
KM401_RS08640	COG0406	alpha-ribazole phosphatase activity
KM401_RS08670	COG0367	asparagine synthase
KM401_RS08700	COG1802	Transcriptional regulator
KM401_RS08705	COG0697	spore germination
KM401_RS08710	COG0523	cobalamin synthesis protein
KM401_RS08715	COG0701	Predicted permease
KM401_RS08725	COG1216	Glycosyl transferase, family 2
KM401_RS08725	COG0438	transferase activity, transferring glycosyl groups
KM401_RS08730	COG1757	Na H antiporter
KM401_RS08735	COG0114	fumarate hydratase activity
KM401_RS08760	COG3340	Belongs to the peptidase S51 family
KM401_RS08780	COG0785	Cytochrome C biogenesis protein
KM401_RS08810	COG2733	membrane
KM401_RS08845	COG1131	(ABC) transporter
KM401_RS08860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_RS08865	COG0528	UMP kinase activity
KM401_RS08875	COG1027	Aspartate ammonia-lyase
KM401_RS08880	COG0281	malic enzyme
KM401_RS08885	COG4191	Histidine kinase
KM401_RS08890	COG0784	Response regulator, receiver
KM401_RS08895	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM401_RS08955	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_RS08965	COG2814	Major facilitator Superfamily
KM401_RS08980	COG1966	Carbon starvation protein
KM401_RS08995	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_RS09005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM401_RS09015	COG2223	nitrite transmembrane transporter activity
KM401_RS09020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM401_RS09035	COG2244	polysaccharide biosynthetic process
KM401_RS09040	COG0733	neurotransmitter:sodium symporter activity
KM401_RS09050	COG5566	PFAM Mor transcription activator
KM401_RS09055	COG2323	membrane
KM401_RS09075	COG2084	Dehydrogenase
KM401_RS09090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM401_RS09100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_RS09105	COG0028	Belongs to the TPP enzyme family
KM401_RS09110	COG0440	acetolactate synthase activity
KM401_RS09115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM401_RS09125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM401_RS09150	COG2814	Major facilitator Superfamily
KM401_RS09155	COG3384	dioxygenase
KM401_RS09165	COG3279	Response regulator of the LytR AlgR family
KM401_RS09170	COG0427	acetyl-CoA hydrolase
KM401_RS09190	COG1073	alpha beta
KM401_RS09220	COG0535	radical SAM domain protein
KM401_RS09225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS09245	COG1914	H( )-stimulated, divalent metal cation uptake system
KM401_RS09260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM401_RS09290	COG2390	Transcriptional regulator
KM401_RS09300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS09305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM401_RS09320	COG4224	UPF0291 protein
KM401_RS09340	COG0006	proline dipeptidase activity
KM401_RS09345	COG2132	Multicopper oxidase
KM401_RS09360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM401_RS09375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM401_RS09390	COG1276	copper resistance
KM401_RS09390	COG2372	response to copper ion
KM401_RS09395	COG4549	nuclear export factor GLE1
KM401_RS09405	COG0697	spore germination
KM401_RS09410	COG0583	DNA-binding transcription factor activity
KM401_RS09415	COG1959	2 iron, 2 sulfur cluster binding
KM401_RS09420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM401_RS09425	COG0778	Nitroreductase
KM401_RS09435	COG0628	permease
KM401_RS09445	COG1231	oxidoreductase activity
KM401_RS09450	COG0523	cobalamin synthesis protein
KM401_RS09465	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_RS09470	COG2030	dehydratase
KM401_RS09475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_RS09485	COG0411	ABC transporter
KM401_RS09505	COG0583	DNA-binding transcription factor activity
KM401_RS09515	COG1942	4-Oxalocrotonate Tautomerase
KM401_RS09535	COG1271	oxidase subunit
KM401_RS09540	COG1294	oxidase, subunit
KM401_RS09545	COG4988	ABC transporter
KM401_RS09550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM401_RS09570	COG1686	Belongs to the peptidase S11 family
KM401_RS09585	COG0791	NLP P60 protein
KM401_RS09585	COG1388	LysM domain
KM401_RS09600	COG0745	RESPONSE REGULATOR receiver
KM401_RS09605	COG5002	protein histidine kinase activity
KM401_RS09615	COG0300	oxidoreductase activity
KM401_RS09650	COG0460	homoserine dehydrogenase
KM401_RS09675	COG1316	TRANSCRIPTIONal
KM401_RS09685	COG0745	RESPONSE REGULATOR receiver
KM401_RS09690	COG5002	protein histidine kinase activity
KM401_RS09705	COG1285	pathogenesis
KM401_RS09710	COG1247	-acetyltransferase
KM401_RS09730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM401_RS09740	COG1082	Xylose isomerase domain protein TIM barrel
KM401_RS09755	COG1279	arginine transmembrane transporter activity
KM401_RS09765	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM401_RS09805	COG2002	toxin-antitoxin pair type II binding
KM401_RS09810	COG1404	Belongs to the peptidase S8 family
KM401_RS09815	COG0640	Transcriptional regulator
KM401_RS09820	COG0667	Aldo Keto reductase
KM401_RS09825	COG2814	Major facilitator Superfamily
KM401_RS09850	COG0840	transmembrane signaling receptor activity
KM401_RS09865	COG3949	Membrane
KM401_RS09870	COG0783	Belongs to the Dps family
KM401_RS09885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM401_RS09895	COG1231	oxidoreductase activity
KM401_RS09905	COG4989	oxidoreductase activity
KM401_RS09910	COG0523	cobalamin synthesis protein
KM401_RS09915	COG0456	acetyltransferase
KM401_RS09975	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM401_RS09975	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM401_RS09985	COG0702	epimerase
KM401_RS09995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM401_RS10005	COG4166	transmembrane transport
KM401_RS10020	COG0406	alpha-ribazole phosphatase activity
KM401_RS10030	COG5337	Spore coat protein CotH
KM401_RS10035	COG1051	belongs to the nudix hydrolase family
KM401_RS10040	COG0586	Pfam SNARE associated Golgi protein
KM401_RS10045	COG2244	polysaccharide biosynthetic process
KM401_RS10055	COG0701	Predicted permease
KM401_RS10060	COG3689	TIGRFAM TIGR03943 family protein
KM401_RS10065	COG1607	acyl-coa hydrolase
KM401_RS10075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_RS10090	COG0702	epimerase
KM401_RS10095	COG2839	Protein conserved in bacteria
KM401_RS10100	COG1253	flavin adenine dinucleotide binding
KM401_RS10115	COG1114	Component of the transport system for branched-chain amino acids
KM401_RS10120	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_RS10140	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_RS10150	COG1876	peptidase activity
KM401_RS10160	COG0154	amidase activity
KM401_RS10165	COG2211	Major facilitator Superfamily
KM401_RS10185	COG0561	phosphatase activity
KM401_RS10195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM401_RS10200	COG4106	trans-aconitate 2-methyltransferase activity
KM401_RS10215	COG1819	glycosyl
KM401_RS10220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS10260	COG0456	acetyltransferase
KM401_RS10315	COG3874	Sporulation protein YtfJ
KM401_RS10340	COG2226	methyltransferase
KM401_RS10365	COG0346	lactoylglutathione lyase activity
KM401_RS10375	COG0604	alcohol dehydrogenase
KM401_RS10380	COG1595	DNA-templated transcription, initiation
KM401_RS10405	COG0386	Belongs to the glutathione peroxidase family
KM401_RS10410	COG1305	Transglutaminase-like
KM401_RS10415	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM401_RS10420	COG0714	Associated with various cellular activities
KM401_RS10435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM401_RS10440	COG1140	nitrate reductase beta subunit
KM401_RS10445	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM401_RS10450	COG2181	nitrate reductase activity
KM401_RS10470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM401_RS10475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM401_RS10480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_RS10485	COG0303	'Molybdopterin
KM401_RS10490	COG0314	molybdopterin synthase activity
KM401_RS10500	COG2223	nitrite transmembrane transporter activity
KM401_RS10515	COG1648	precorrin-2 dehydrogenase activity
KM401_RS10525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM401_RS10525	COG1587	Uroporphyrinogen-III synthase
KM401_RS10530	COG2146	nitrite reductase [NAD(P)H] activity
KM401_RS10535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM401_RS10540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM401_RS10575	COG2359	stage V sporulation protein S
KM401_RS10600	COG1418	mRNA catabolic process
KM401_RS10605	COG0488	(ABC) transporter
KM401_RS10620	COG0629	single-stranded DNA binding
KM401_RS10635	COG1413	lyase activity
KM401_RS10650	COG2136	Putative SAM-dependent methyltransferase
KM401_RS10650	COG2521	methyltransferase
KM401_RS10655	COG0018	arginyl-trna synthetase
KM401_RS10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM401_RS10700	COG0017	Asparaginyl-tRNA synthetase
KM401_RS10720	COG1674	ftsk spoiiie
KM401_RS10790	COG1929	Belongs to the glycerate kinase type-1 family
KM401_RS10795	COG0471	metal ion transport
KM401_RS10800	COG0745	RESPONSE REGULATOR receiver
KM401_RS10805	COG3850	Histidine kinase
KM401_RS10805	COG5002	protein histidine kinase activity
KM401_RS10820	COG0733	neurotransmitter:sodium symporter activity
KM401_RS10845	COG2610	gluconate transmembrane transporter activity
KM401_RS10850	COG1454	alcohol dehydrogenase
KM401_RS10855	COG1794	racemase activity, acting on amino acids and derivatives
KM401_RS10865	COG0456	acetyltransferase
KM401_RS10880	COG1131	(ABC) transporter
KM401_RS10895	COG0546	phosphoglycolate phosphatase activity
KM401_RS10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_RS10930	COG0768	penicillin binding
KM401_RS10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM401_RS10940	COG0204	Acyl-transferase
KM401_RS10945	COG1272	protein, Hemolysin III
KM401_RS10955	COG0805	protein transport
KM401_RS10965	COG1307	EDD domain protein, DegV family
KM401_RS10970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM401_RS10975	COG1999	signal sequence binding
KM401_RS10980	COG0071	Belongs to the small heat shock protein (HSP20) family
KM401_RS10985	COG0367	asparagine synthase
KM401_RS11000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_RS11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM401_RS11040	COG0668	transmembrane transport
KM401_RS11045	COG2203	Gaf domain
KM401_RS11045	COG4585	Histidine kinase
KM401_RS11050	COG2197	response regulator
KM401_RS11060	COG1064	alcohol dehydrogenase
KM401_RS11115	COG0517	IMP dehydrogenase activity
KM401_RS11115	COG1125	glycine betaine transport
KM401_RS11120	COG1174	glycine betaine transport
KM401_RS11155	COG1253	flavin adenine dinucleotide binding
KM401_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS11165	COG5506	Protein of unknown function (DUF1694)
KM401_RS11180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM401_RS11185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM401_RS11190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM401_RS11195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM401_RS11200	COG0456	acetyltransferase
KM401_RS11205	COG3829	transcription factor binding
KM401_RS11210	COG1509	lysine 2,3-aminomutase activity
KM401_RS11250	COG4326	sporulation control protein
KM401_RS11255	COG0671	phosphoesterase, PA-phosphatase related
KM401_RS11260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM401_RS11265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_RS11295	COG1715	Restriction endonuclease
KM401_RS11295	COG1787	Restriction endonuclease
KM401_RS11385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM401_RS11425	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM401_RS11425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_RS11435	COG2814	Major facilitator Superfamily
KM401_RS11440	COG4841	protein insertion into membrane
KM401_RS11445	COG0372	Belongs to the citrate synthase family
KM401_RS11450	COG2079	MmgE PrpD family protein
KM401_RS11455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM401_RS11460	COG1960	acyl-CoA dehydrogenase activity
KM401_RS11465	COG2084	Dehydrogenase
KM401_RS11475	COG1280	lysine exporter protein (LysE YggA)
KM401_RS11480	COG1024	Enoyl-CoA hydratase
KM401_RS11495	COG0420	3'-5' exonuclease activity
KM401_RS11500	COG0419	ATPase involved in DNA repair
KM401_RS11525	COG2223	nitrite transmembrane transporter activity
KM401_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS11535	COG1169	isochorismate synthase
KM401_RS11540	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM401_RS11545	COG1535	isochorismatase
KM401_RS11545	COG3433	isochorismatase activity
KM401_RS11550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM401_RS11555	COG3251	PFAM MbtH domain protein
KM401_RS11560	COG2814	Major facilitator Superfamily
KM401_RS11575	COG0776	regulation of translation
KM401_RS11585	COG2318	DinB family
KM401_RS11595	COG1115	amino acid carrier protein
KM401_RS11610	COG2329	Antibiotic biosynthesis monooxygenase
KM401_RS11615	COG1187	pseudouridine synthase activity
KM401_RS11620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM401_RS11635	COG0596	Alpha beta hydrolase
KM401_RS11640	COG2814	Major facilitator Superfamily
KM401_RS11660	COG2226	methyltransferase
KM401_RS11705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS11740	COG1247	-acetyltransferase
KM401_RS11770	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM401_RS11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS11790	COG1278	Cold shock
KM401_RS11805	COG0010	Belongs to the arginase family
KM401_RS11810	COG0561	phosphatase activity
KM401_RS11855	COG0583	DNA-binding transcription factor activity
KM401_RS11860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM401_RS11875	COG0583	DNA-binding transcription factor activity
KM401_RS11880	COG2258	MOSC domain
KM401_RS11895	COG1132	(ABC) transporter
KM401_RS11900	COG1132	(ABC) transporter
KM401_RS11920	COG1396	sequence-specific DNA binding
KM401_RS11945	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM401_RS11950	COG1595	DNA-templated transcription, initiation
KM401_RS11975	COG1649	PFAM Uncharacterised BCR, COG1649
KM401_RS12000	COG2971	BadF BadG BcrA BcrD
KM401_RS12005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM401_RS12010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM401_RS12030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS12060	COG1309	transcriptional regulator
KM401_RS12075	COG1136	(ABC) transporter
KM401_RS12075	COG0577	efflux transmembrane transporter activity
KM401_RS12080	COG0500	methyltransferase
KM401_RS12080	COG3615	Tellurite resistance protein tehB
KM401_RS12090	COG2226	methyltransferase
KM401_RS12095	COG3961	Belongs to the TPP enzyme family
KM401_RS12100	COG1846	Transcriptional regulator
KM401_RS12140	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM401_RS12155	COG1595	DNA-templated transcription, initiation
KM401_RS12165	COG0768	penicillin binding
KM401_RS12175	COG2367	Beta-lactamase
KM401_RS12180	COG0671	phosphoesterase, PA-phosphatase related
KM401_RS12185	COG1609	Transcriptional regulator
KM401_RS12190	COG2814	Major facilitator Superfamily
KM401_RS12195	COG0673	inositol 2-dehydrogenase activity
KM401_RS12205	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS12220	COG0191	fructose-bisphosphate aldolase activity
KM401_RS12225	COG3718	enzyme involved in inositol metabolism
KM401_RS12250	COG0457	Tetratricopeptide repeat
KM401_RS12255	COG1476	TRANSCRIPTIONal
KM401_RS12270	COG1876	peptidase activity
KM401_RS12290	COG1309	transcriptional regulator
KM401_RS12295	COG0488	(ABC) transporter
KM401_RS12310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS12325	COG1252	NADH dehydrogenase
KM401_RS12330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_RS12345	COG1131	(ABC) transporter
KM401_RS12355	COG1309	transcriptional regulator
KM401_RS12370	COG1960	acyl-CoA dehydrogenase activity
KM401_RS12375	COG0439	Biotin carboxylase
KM401_RS12380	COG0511	ligase activity, forming carbon-carbon bonds
KM401_RS12385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM401_RS12390	COG1024	Enoyl-CoA hydratase
KM401_RS12395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM401_RS12400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM401_RS12410	COG1247	-acetyltransferase
KM401_RS12415	COG0572	uridine kinase
KM401_RS12425	COG2318	DinB family
KM401_RS12430	COG1686	Belongs to the peptidase S11 family
KM401_RS12455	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM401_RS12495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM401_RS12495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM401_RS12520	COG2814	Major facilitator Superfamily
KM401_RS12540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM401_RS12560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_RS12575	COG1063	alcohol dehydrogenase
KM401_RS12590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM401_RS12595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM401_RS12610	COG3773	Cell wall hydrolase
KM401_RS12620	COG0745	RESPONSE REGULATOR receiver
KM401_RS12635	COG0488	(ABC) transporter
KM401_RS12650	COG1136	(ABC) transporter
KM401_RS12675	COG0460	homoserine dehydrogenase
KM401_RS12680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_RS12690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM401_RS12755	COG2124	cytochrome p450
KM401_RS12790	COG0561	phosphatase activity
KM401_RS12800	COG0768	penicillin binding
KM401_RS12805	COG1819	glycosyl
KM401_RS12810	COG1794	racemase activity, acting on amino acids and derivatives
KM401_RS12820	COG1122	ATPase activity
KM401_RS12835	COG2205	protein histidine kinase activity
KM401_RS12845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_RS12850	COG0604	alcohol dehydrogenase
KM401_RS12855	COG0768	penicillin binding
KM401_RS12865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_RS12900	COG0693	protein deglycase activity
KM401_RS12930	COG2814	Major facilitator Superfamily
KM401_RS12945	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_RS12965	COG0697	spore germination
KM401_RS12995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_RS13005	COG2223	nitrite transmembrane transporter activity
KM401_RS13020	COG2816	NAD+ diphosphatase activity
KM401_RS13025	COG0592	DNA-directed DNA polymerase activity
KM401_RS13030	COG1051	belongs to the nudix hydrolase family
KM401_RS13065	COG3878	Protein conserved in bacteria
KM401_RS13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM401_RS13130	COG0322	excinuclease ABC activity
KM401_RS13170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_RS13195	COG1011	Hydrolase
KM401_RS13215	COG0076	glutamate decarboxylase activity
KM401_RS13230	COG1523	belongs to the glycosyl hydrolase 13 family
KM401_RS13235	COG3227	Zinc metalloprotease (Elastase)
KM401_RS13255	COG0201	protein transport
KM401_RS13265	COG0697	spore germination
KM401_RS13270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_RS13300	COG4129	membrane
KM401_RS13305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS13320	COG2959	enzyme of heme biosynthesis
KM401_RS13340	COG3483	tryptophan 2,3-dioxygenase activity
KM401_RS13345	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM401_RS13350	COG3844	kynureninase activity
KM401_RS13355	COG1309	transcriptional regulator
KM401_RS13385	COG3284	Transcriptional regulator
KM401_RS13405	COG1349	DNA-binding transcription factor activity
KM401_RS13425	COG1959	2 iron, 2 sulfur cluster binding
KM401_RS13440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM401_RS13445	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_RS13450	COG0022	dehydrogenase e1 component
KM401_RS13455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM401_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS13470	COG0456	acetyltransferase
KM401_RS13470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_RS13500	COG4176	ABC-type proline glycine betaine transport system permease component
KM401_RS13505	COG4175	Glycine betaine
KM401_RS13505	COG0517	IMP dehydrogenase activity
KM401_RS13530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM401_RS13535	COG2153	protein acetylation
KM401_RS13540	COG3397	chitin binding
KM401_RS13555	COG2205	protein histidine kinase activity
KM401_RS13580	COG2333	competence protein COMEC
KM401_RS13580	COG0658	competence protein
KM401_RS13630	COG3973	AAA domain
KM401_RS13645	COG2105	PFAM AIG2 family protein
KM401_RS13650	COG0514	ATP-dependent DNA helicase (RecQ)
KM401_RS13670	COG4637	Psort location Cytoplasmic, score
KM401_RS13695	COG3397	chitin binding
KM401_RS13710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM401_RS13715	COG1115	amino acid carrier protein
KM401_RS13720	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS13725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM401_RS13735	COG3938	Belongs to the proline racemase family
KM401_RS13740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM401_RS13780	COG0586	Pfam SNARE associated Golgi protein
KM401_RS13795	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM401_RS13800	COG0519	Catalyzes the synthesis of GMP from XMP
KM401_RS13805	COG4166	transmembrane transport
KM401_RS13815	COG4948	Mandelate Racemase Muconate Lactonizing
KM401_RS13860	COG2936	dipeptidyl-peptidase activity
KM401_RS13865	COG5002	protein histidine kinase activity
KM401_RS13915	COG1307	EDD domain protein, DegV family
KM401_RS13935	COG2814	Major facilitator Superfamily
KM401_RS13945	COG1664	Polymer-forming cytoskeletal
KM401_RS13950	COG0789	Transcriptional regulator
KM401_RS13955	COG4533	DNA binding
KM401_RS13960	COG2814	Major facilitator Superfamily
KM401_RS13960	COG0477	Major facilitator Superfamily
KM401_RS13980	COG2261	transglycosylase associated protein
KM401_RS13995	COG2226	methyltransferase
KM401_RS14030	COG0436	Aminotransferase
KM401_RS14035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM401_RS14040	COG5146	pantothenate kinase activity
KM401_RS14060	COG1131	(ABC) transporter
KM401_RS14105	COG0628	permease
KM401_RS14120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM401_RS14125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_RS14130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM401_RS14135	COG1116	anion transmembrane transporter activity
KM401_RS14155	COG2816	NAD+ diphosphatase activity
KM401_RS14175	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM401_RS14200	COG0697	spore germination
KM401_RS14205	COG2318	DinB family
KM401_RS14225	COG4912	Dna alkylation repair
KM401_RS14245	COG0861	Integral membrane protein TerC family
KM401_RS14250	COG1368	sulfuric ester hydrolase activity
KM401_RS14255	COG0488	(ABC) transporter
KM401_RS14270	COG1309	transcriptional regulator
KM401_RS14285	COG0287	Prephenate dehydrogenase
KM401_RS14290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM401_RS14295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM401_RS14300	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM401_RS14300	COG1605	Chorismate mutase
KM401_RS14335	COG3584	3D domain protein
KM401_RS14335	COG1388	LysM domain
KM401_RS14345	COG1595	DNA-templated transcription, initiation
KM401_RS14370	COG1879	ABC-type sugar transport system periplasmic component
KM401_RS14380	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM401_RS14390	COG2390	Transcriptional regulator
KM401_RS14425	COG2329	Antibiotic biosynthesis monooxygenase
KM401_RS14445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS14455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM401_RS14460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_RS14465	COG4187	Peptidase family M20/M25/M40
KM401_RS14470	COG1414	Transcriptional regulator
KM401_RS14475	COG0833	amino acid
KM401_RS14480	COG1690	Belongs to the RtcB family
KM401_RS14490	COG1785	Belongs to the alkaline phosphatase family
KM401_RS14500	COG3655	Transcriptional regulator
KM401_RS14515	COG4377	Putative membrane peptidase family (DUF2324)
KM401_RS14525	COG3279	Response regulator of the LytR AlgR family
KM401_RS14535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS14540	COG0346	lactoylglutathione lyase activity
KM401_RS14560	COG0714	Associated with various cellular activities
KM401_RS14585	COG0463	Glycosyl transferase, family 2
KM401_RS14605	COG0463	Glycosyl transferase, family 2
KM401_RS14615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM401_RS14620	COG0753	catalase activity
KM401_RS14630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM401_RS14655	COG0714	Associated with various cellular activities
KM401_RS14665	COG0778	Nitroreductase
KM401_RS14670	COG1846	Transcriptional regulator
KM401_RS14705	COG1725	Transcriptional regulator
KM401_RS14715	COG1136	(ABC) transporter
KM401_RS14715	COG0577	efflux transmembrane transporter activity
KM401_RS14740	COG2207	Transcriptional regulator
KM401_RS14745	COG0456	acetyltransferase
KM401_RS14765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_RS14785	COG0642	Histidine kinase
KM401_RS14790	COG0745	RESPONSE REGULATOR receiver
KM401_RS14795	COG0596	Alpha beta hydrolase
KM401_RS14825	COG0730	response to heat
KM401_RS14835	COG0833	amino acid
KM401_RS14845	COG4335	DNA alkylation repair
KM401_RS14885	COG0768	penicillin binding
KM401_RS14895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM401_RS14930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM401_RS14935	COG1414	Transcriptional regulator
KM401_RS14950	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM401_RS14955	COG0640	Transcriptional regulator
KM401_RS14965	COG1960	acyl-CoA dehydrogenase activity
KM401_RS14980	COG3314	Sporulation integral membrane protein YlbJ
KM401_RS14995	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM401_RS15010	COG3848	Pyruvate phosphate dikinase
KM401_RS15010	COG0574	Belongs to the PEP-utilizing enzyme family
KM401_RS15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS15030	COG5577	PFAM Coat F domain
KM401_RS15035	COG3403	YqcI/YcgG family
KM401_RS15040	COG1280	lysine exporter protein (LysE YggA)
KM401_RS15075	COG1063	alcohol dehydrogenase
KM401_RS15090	COG1027	Aspartate ammonia-lyase
KM401_RS15095	COG0252	asparaginase activity
KM401_RS15100	COG1396	sequence-specific DNA binding
KM401_RS15110	COG0322	excinuclease ABC activity
KM401_RS15115	COG0531	amino acid
KM401_RS15120	COG1114	Component of the transport system for branched-chain amino acids
KM401_RS15125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_RS15135	COG0281	malic enzyme
KM401_RS15150	COG0531	amino acid
KM401_RS15160	COG0784	Response regulator, receiver
KM401_RS15170	COG2066	Belongs to the glutaminase family
KM401_RS15175	COG1115	amino acid carrier protein
KM401_RS15205	COG0737	Belongs to the 5'-nucleotidase family
KM401_RS15210	COG0753	catalase activity
KM401_RS15215	COG2267	carboxylic ester hydrolase activity
KM401_RS15220	COG1335	isochorismatase
KM401_RS15240	COG0583	DNA-binding transcription factor activity
KM401_RS15290	COG0415	Belongs to the DNA photolyase family
KM401_RS15295	COG0288	reversible hydration of carbon dioxide
KM401_RS15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM401_RS15310	COG5609	conserved protein (DUF2294)
KM401_RS15325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM401_RS15330	COG2267	carboxylic ester hydrolase activity
KM401_RS15335	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM401_RS15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM401_RS15345	COG1121	(ABC) transporter
KM401_RS15375	COG0798	PFAM Bile acid sodium symporter
KM401_RS15380	COG0346	lactoylglutathione lyase activity
KM401_RS15385	COG0640	Transcriptional regulator
KM401_RS15400	COG0443	Heat shock 70 kDa protein
KM401_RS15415	COG1522	sequence-specific DNA binding
KM401_RS15430	COG0346	lactoylglutathione lyase activity
KM401_RS15450	COG2169	Transcriptional regulator
KM401_RS15455	COG2169	Transcriptional regulator
KM401_RS15500	COG2814	Major facilitator Superfamily
KM401_RS15525	COG0745	RESPONSE REGULATOR receiver
KM401_RS15530	COG3850	Histidine kinase
KM401_RS15530	COG5002	protein histidine kinase activity
KM401_RS15555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM401_RS15575	COG1476	TRANSCRIPTIONal
KM401_RS15590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS15595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM401_RS15605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_RS15610	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM401_RS15625	COG1136	(ABC) transporter
KM401_RS15630	COG0577	efflux transmembrane transporter activity
KM401_RS15645	COG5002	protein histidine kinase activity
KM401_RS15645	COG3850	Histidine kinase
KM401_RS15655	COG2364	Membrane
KM401_RS15660	COG1846	Transcriptional regulator
KM401_RS15670	COG2808	Putative FMN-binding domain
KM401_RS15675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS15680	COG2271	Major facilitator Superfamily
KM401_RS15685	COG1556	Lactate utilization protein
KM401_RS15690	COG1139	Iron-sulfur cluster binding protein
KM401_RS15700	COG0583	DNA-binding transcription factor activity
KM401_RS15710	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM401_RS15735	COG0738	Major facilitator superfamily
KM401_RS15740	COG0673	inositol 2-dehydrogenase activity
KM401_RS15745	COG0561	phosphatase activity
KM401_RS15755	COG1609	Transcriptional regulator
KM401_RS15760	COG0457	Tetratricopeptide repeat
KM401_RS15780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM401_RS15810	COG0534	Mate efflux family protein
KM401_RS15830	COG2814	Major facilitator Superfamily
KM401_RS15835	COG1309	transcriptional regulator
KM401_RS15850	COG0814	amino acid
KM401_RS15855	COG1760	l-serine dehydratase
KM401_RS15860	COG1760	l-serine dehydratase
KM401_RS15870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM401_RS15875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM401_RS15885	COG1335	isochorismatase
KM401_RS15890	COG1522	sequence-specific DNA binding
KM401_RS15895	COG0531	amino acid
KM401_RS15915	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM401_RS15935	COG1595	DNA-templated transcription, initiation
KM401_RS15950	COG0662	Cupin 2, conserved barrel domain protein
KM401_RS15955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_RS15955	COG2207	Transcriptional regulator
KM401_RS16005	COG0477	Major facilitator Superfamily
KM401_RS16015	COG1846	Transcriptional regulator
KM401_RS16020	COG2814	Major facilitator Superfamily
KM401_RS16030	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM401_RS16035	COG1131	(ABC) transporter
KM401_RS16055	COG2076	Multidrug Resistance protein
KM401_RS16060	COG1309	transcriptional regulator
KM401_RS16070	COG2031	fatty acid transporter
KM401_RS16080	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM401_RS16110	COG1122	ATPase activity
KM401_RS16115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM401_RS16130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM401_RS16135	COG1288	antiporter activity
KM401_RS16140	COG2356	endonuclease I
KM401_RS16155	COG3620	sequence-specific DNA binding
KM401_RS16160	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM401_RS16165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM401_RS16170	COG0124	histidyl-tRNA synthetase
KM401_RS16185	COG1733	regulation of RNA biosynthetic process
KM401_RS16190	COG0778	Nitroreductase
KM401_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS16220	COG1131	(ABC) transporter
KM401_RS16245	COG1011	Hydrolase
KM401_RS16255	COG2365	Tyrosine phosphatase family
KM401_RS16280	COG0346	lactoylglutathione lyase activity
KM401_RS16285	COG1940	carbohydrate kinase activity
KM401_RS16290	COG0738	Major facilitator superfamily
KM401_RS16295	COG0110	maltose O-acetyltransferase activity
KM401_RS16305	COG0577	efflux transmembrane transporter activity
KM401_RS16305	COG1136	(ABC) transporter
KM401_RS16320	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM401_RS16325	COG0628	permease
KM401_RS16345	COG2226	methyltransferase
KM401_RS16355	COG0477	Major facilitator Superfamily
KM401_RS16385	COG1253	flavin adenine dinucleotide binding
KM401_RS16390	COG0789	Transcriptional regulator
KM401_RS16395	COG0697	spore germination
KM401_RS16400	COG1357	PFAM Pentapeptide repeats (8 copies)
KM401_RS16405	COG3813	Protein conserved in bacteria
KM401_RS16410	COG2706	6-phosphogluconolactonase activity
KM401_RS16415	COG1070	Carbohydrate kinase
KM401_RS16425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM401_RS16430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM401_RS16440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM401_RS16445	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM401_RS16450	COG0604	alcohol dehydrogenase
KM401_RS16455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM401_RS16465	COG0604	alcohol dehydrogenase
KM401_RS16465	COG3321	synthase
KM401_RS16470	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS16495	COG0656	L-ascorbic acid biosynthetic process
KM401_RS16500	COG2814	Major facilitator Superfamily
KM401_RS16515	COG0346	lactoylglutathione lyase activity
KM401_RS16520	COG0814	amino acid
KM401_RS16545	COG1393	Belongs to the ArsC family
KM401_RS16550	COG1733	regulation of RNA biosynthetic process
KM401_RS16555	COG2188	Transcriptional regulator
KM401_RS16565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM401_RS16570	COG1733	regulation of RNA biosynthetic process
KM401_RS16575	COG1733	regulation of RNA biosynthetic process
KM401_RS16590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS16610	COG0384	phenazine biosynthesis protein PhzF
KM401_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS16630	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_RS16640	COG1733	regulation of RNA biosynthetic process
KM401_RS16670	COG1191	sigma factor activity
KM401_RS16685	COG1309	transcriptional regulator
KM401_RS16705	COG3152	Membrane
KM401_RS16730	COG1151	hydroxylamine reductase activity
KM401_RS16740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS16745	COG3757	hydrolase, family 25
KM401_RS16745	COG3409	Peptidoglycan-binding domain 1 protein
KM401_RS16780	COG2072	flavoprotein involved in K transport
KM401_RS16815	COG0604	alcohol dehydrogenase
KM401_RS16820	COG1113	amino acid transport
KM401_RS16825	COG2814	Major facilitator Superfamily
KM401_RS16855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM401_RS16860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM401_RS16885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS16890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS16895	COG3739	integral membrane protein
KM401_RS16900	COG0384	phenazine biosynthesis protein PhzF
KM401_RS16930	COG0583	DNA-binding transcription factor activity
KM401_RS16950	COG1193	negative regulation of DNA recombination
KM401_RS16975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM401_RS17005	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_RS17030	COG0640	Transcriptional regulator
KM401_RS17035	COG0604	alcohol dehydrogenase
KM401_RS17055	COG2808	Putative FMN-binding domain
KM401_RS17060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_RS17070	COG0385	Bile acid
KM401_RS17075	COG0277	FAD linked oxidase domain protein
KM401_RS17105	COG1216	Glycosyl transferase, family 2
KM401_RS17110	COG1024	Enoyl-CoA hydratase
KM401_RS17120	COG1285	pathogenesis
KM401_RS17135	COG2514	catechol 2,3-dioxygenase activity
KM401_RS17140	COG2720	vancomycin resistance protein
KM401_RS17180	COG0716	FMN binding
KM401_RS17210	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS17220	COG0165	Argininosuccinate lyase
KM401_RS17235	COG4145	pantothenate transmembrane transporter activity
KM401_RS17245	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS17260	COG1657	PFAM Prenyltransferase squalene oxidase
KM401_RS17265	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM401_RS17270	COG2962	Rard protein
KM401_RS17275	COG3326	Membrane
KM401_RS17290	COG0489	protein tyrosine kinase activity
KM401_RS17300	COG0314	molybdopterin synthase activity
KM401_RS17305	COG0303	'Molybdopterin
KM401_RS17310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_RS17315	COG2116	formate transmembrane transporter activity
KM401_RS17325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM401_RS17330	COG5609	conserved protein (DUF2294)
KM401_RS17335	COG2427	Protein of unknown function (DUF1641)
KM401_RS17340	COG3383	formate dehydrogenase (NAD+) activity
KM401_RS17350	COG0697	spore germination
KM401_RS17390	COG2226	methyltransferase
KM401_RS17395	COG4166	transmembrane transport
KM401_RS17400	COG4166	transmembrane transport
KM401_RS17405	COG4166	transmembrane transport
KM401_RS17410	COG1301	dicarboxylic acid transport
KM401_RS17415	COG1316	TRANSCRIPTIONal
KM401_RS17425	COG1595	DNA-templated transcription, initiation
KM401_RS17445	COG1131	(ABC) transporter
KM401_RS17455	COG0673	inositol 2-dehydrogenase activity
KM401_RS17460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM401_RS17465	COG0187	DNA topoisomerase II activity
KM401_RS17470	COG1832	CoA-binding protein
KM401_RS17475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM401_RS17480	COG0745	RESPONSE REGULATOR receiver
KM401_RS17495	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM401_RS17500	COG4841	protein insertion into membrane
KM401_RS17505	COG0824	Thioesterase
KM401_RS17535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_RS17545	COG2274	protein secretion by the type I secretion system
KM401_RS17550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM401_RS17590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM401_RS17605	COG0183	Belongs to the thiolase family
KM401_RS17610	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_RS17615	COG1268	BioY protein
KM401_RS17620	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_RS17670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS17680	COG5002	protein histidine kinase activity
KM401_RS17685	COG0400	carboxylic ester hydrolase activity
KM401_RS17690	COG0346	lactoylglutathione lyase activity
KM401_RS17695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM401_RS17700	COG0069	glutamate synthase activity
KM401_RS17705	COG1902	pentaerythritol trinitrate reductase activity
KM401_RS17710	COG1329	Transcriptional regulator
KM401_RS17715	COG0010	Belongs to the arginase family
KM401_RS17740	COG2226	methyltransferase
KM401_RS17775	COG4846	Membrane protein involved in cytochrome C biogenesis
KM401_RS17780	COG0785	Cytochrome C biogenesis protein
KM401_RS17790	COG0583	DNA-binding transcription factor activity
KM401_RS17795	COG1380	Effector of murein hydrolase LrgA
KM401_RS17800	COG1346	cytolysis
KM401_RS17825	COG3409	Peptidoglycan-binding domain 1 protein
KM401_RS17825	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM401_RS17840	COG1132	(ABC) transporter
KM401_RS17845	COG1132	(ABC) transporter
KM401_RS17875	COG3639	organic phosphonate transmembrane transporter activity
KM401_RS17880	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM401_RS17900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM401_RS17920	COG1695	Transcriptional regulator
KM401_RS17960	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM401_RS17960	COG1388	LysM domain
KM401_RS17960	COG3409	Peptidoglycan-binding domain 1 protein
KM401_RS17965	COG4824	toxin secretion phage lysis holin
KM401_RS18120	COG1595	DNA-templated transcription, initiation
KM401_RS18165	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM401_RS18250	COG1396	sequence-specific DNA binding
KM401_RS18275	COG0174	glutamine synthetase
KM401_RS18280	COG0789	Transcriptional regulator
KM401_RS18285	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM401_RS18295	COG2860	membrane
KM401_RS18300	COG0464	growth
KM401_RS18330	COG3584	3D domain protein
KM401_RS18330	COG1388	LysM domain
KM401_RS18335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM401_RS18335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM401_RS18335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM401_RS18340	COG1105	Belongs to the carbohydrate kinase PfkB family
KM401_RS18345	COG1349	DNA-binding transcription factor activity
KM401_RS18355	COG2322	membrane
KM401_RS18365	COG1113	amino acid transport
KM401_RS18380	COG1408	metallophosphoesterase
KM401_RS18385	COG2116	formate transmembrane transporter activity
KM401_RS18395	COG2217	Heavy metal translocating P-type atpase
KM401_RS18400	COG2608	mercury ion transmembrane transporter activity
KM401_RS18405	COG1937	Protein conserved in bacteria
KM401_RS18415	COG2819	hydrolase of the alpha beta superfamily
KM401_RS18420	COG1120	ATPase activity
KM401_RS18425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS18430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS18440	COG0708	Exodeoxyribonuclease III
KM401_RS18445	COG2169	Transcriptional regulator
KM401_RS18450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM401_RS18455	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM401_RS18465	COG2364	Membrane
KM401_RS18480	COG2267	carboxylic ester hydrolase activity
KM401_RS18485	COG0346	lactoylglutathione lyase activity
KM401_RS18490	COG3300	MHYT domain
KM401_RS18490	COG5001	Diguanylate cyclase
KM401_RS18510	COG1346	cytolysis
KM401_RS18515	COG1380	Effector of murein hydrolase LrgA
KM401_RS18520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM401_RS18525	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_RS18525	COG0596	Alpha beta hydrolase
KM401_RS18530	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM401_RS18550	COG1404	Belongs to the peptidase S8 family
KM401_RS18555	COG3773	Cell wall hydrolase
KM401_RS18560	COG0562	UDP-galactopyranose mutase
KM401_RS18565	COG1368	sulfuric ester hydrolase activity
KM401_RS18570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM401_RS18580	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM401_RS18605	COG1131	(ABC) transporter
KM401_RS18625	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM401_RS18630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM401_RS18635	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM401_RS18640	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM401_RS18640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM401_RS18650	COG2359	stage V sporulation protein S
KM401_RS18655	COG1692	metallophosphoesterase
KM401_RS18680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM401_RS18685	COG1426	Protein conserved in bacteria
KM401_RS18700	COG0300	oxidoreductase activity
KM401_RS18705	COG0612	Peptidase, M16
KM401_RS18710	COG0612	Peptidase, M16
KM401_RS18715	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM401_RS18725	COG3845	ABC transporter
KM401_RS18730	COG1744	ABC transporter substrate-binding protein PnrA-like
KM401_RS18735	COG2188	Transcriptional regulator
KM401_RS18740	COG1674	ftsk spoiiie
KM401_RS18750	COG0740	serine-type endopeptidase activity
KM401_RS18755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM401_RS18765	COG0527	aspartate kinase activity
KM401_RS18770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM401_RS18775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM401_RS18780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM401_RS18785	COG1873	PFAM PRC-barrel domain
KM401_RS18790	COG0612	Peptidase, M16
KM401_RS18795	COG0726	polysaccharide deacetylase
KM401_RS18810	COG0196	riboflavin kinase activity
KM401_RS18815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM401_RS18825	COG1550	Protein conserved in bacteria
KM401_RS18835	COG1358	cellular component organization or biogenesis
KM401_RS18840	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM401_RS18845	COG0195	Participates in both transcription termination and antitermination
KM401_RS18865	COG0750	zinc metalloprotease
KM401_RS18875	COG4589	Belongs to the CDS family
KM401_RS18880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM401_RS18890	COG0528	UMP kinase activity
KM401_RS18920	COG4974	Belongs to the 'phage' integrase family
KM401_RS18930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM401_RS18940	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM401_RS18980	COG1837	Belongs to the UPF0109 family
KM401_RS18990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM401_RS19000	COG0552	protein localization to endoplasmic reticulum
KM401_RS19005	COG1196	nuclear chromosome segregation
KM401_RS19015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM401_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS19025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM401_RS19040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM401_RS19045	COG1461	Dihydroxyacetone kinase
KM401_RS19050	COG1302	Protein conserved in bacteria
KM401_RS19065	COG1564	THIamine pyrophosphokinase
KM401_RS19070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM401_RS19075	COG1162	GTPase activity
KM401_RS19080	COG0515	serine threonine protein kinase
KM401_RS19080	COG2815	serine threonine protein kinase
KM401_RS19085	COG0631	protein serine/threonine phosphatase activity
KM401_RS19095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM401_RS19095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM401_RS19105	COG0242	peptide deformylase activity
KM401_RS19110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM401_RS19115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM401_RS19135	COG1561	YicC-like family, N-terminal region
KM401_RS19140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM401_RS19150	COG0006	proline dipeptidase activity
KM401_RS19165	COG3069	C4-dicarboxylate transmembrane transporter activity
KM401_RS19230	COG0564	pseudouridine synthase activity
KM401_RS19250	COG3599	regulation of cell shape
KM401_RS19255	COG2302	S4 RNA-binding domain
KM401_RS19260	COG0762	integral membrane protein
KM401_RS19270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM401_RS19275	COG1496	oxidoreductase activity
KM401_RS19280	COG1873	PFAM PRC-barrel domain
KM401_RS19285	COG1191	sigma factor activity
KM401_RS19290	COG1191	sigma factor activity
KM401_RS19300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM401_RS19305	COG0849	cell division
KM401_RS19310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM401_RS19315	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM401_RS19325	COG0772	Belongs to the SEDS family
KM401_RS19340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM401_RS19345	COG0768	penicillin binding
KM401_RS19350	COG0768	penicillin binding
KM401_RS19355	COG4839	cell division protein FtsL
KM401_RS19370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM401_RS19385	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM401_RS19390	COG1399	metal-binding, possibly nucleic acid-binding protein
KM401_RS19440	COG4824	toxin secretion phage lysis holin
KM401_RS19535	COG4626	Terminase
KM401_RS19535	COG1802	Transcriptional regulator
KM401_RS19560	COG0582	viral genome integration into host DNA
KM401_RS19625	COG0756	dUTP diphosphatase activity
KM401_RS19640	COG1191	sigma factor activity
KM401_RS19665	COG1484	DNA-dependent DNA replication
KM401_RS19695	COG1396	sequence-specific DNA binding
KM401_RS19710	COG1396	sequence-specific DNA binding
KM401_RS19725	COG0582	viral genome integration into host DNA
KM401_RS19735	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM401_RS19740	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM401_RS19745	COG3314	Sporulation integral membrane protein YlbJ
KM401_RS19755	COG0742	ribosomal rna small subunit methyltransferase
KM401_RS19770	COG3679	Belongs to the UPF0342 family
KM401_RS19775	COG0406	alpha-ribazole phosphatase activity
KM401_RS19790	COG2340	Cysteine-rich secretory protein family
KM401_RS19805	COG3336	cytochrome c oxidase
KM401_RS19840	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM401_RS19845	COG0772	Belongs to the SEDS family
KM401_RS19855	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM401_RS19860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM401_RS19870	COG4896	Protein conserved in bacteria
KM401_RS19885	COG1217	gtp-binding protein TYPA
KM401_RS19895	COG0483	inositol monophosphate 1-phosphatase activity
KM401_RS19915	COG1982	Orn Lys Arg decarboxylase major
KM401_RS19960	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_RS19965	COG0022	dehydrogenase e1 component
KM401_RS19970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM401_RS19980	COG0242	peptide deformylase activity
KM401_RS19985	COG0561	phosphatase activity
KM401_RS19995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM401_RS20000	COG0569	domain protein
KM401_RS20020	COG0583	DNA-binding transcription factor activity
KM401_RS20025	COG0517	IMP dehydrogenase activity
KM401_RS20035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM401_RS20045	COG4703	Protein of unknown function (DUF1797)
KM401_RS20060	COG2200	EAL domain
KM401_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS20070	COG1408	metallophosphoesterase
KM401_RS20080	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM401_RS20115	COG2814	Major facilitator Superfamily
KM401_RS20135	COG3209	COG3209 Rhs family protein
KM401_RS20145	COG2205	protein histidine kinase activity
KM401_RS20155	COG0436	Aminotransferase
KM401_RS20160	COG1609	Transcriptional regulator
KM401_RS20165	COG3833	ABC-type maltose transport systems, permease component
KM401_RS20170	COG1175	transmembrane transport
KM401_RS20175	COG2182	Extracellular solute-binding protein
KM401_RS20185	COG0366	Alpha amylase catalytic
KM401_RS20190	COG3842	ATPase activity
KM401_RS20230	COG0183	Belongs to the thiolase family
KM401_RS20265	COG1695	Transcriptional regulator
KM401_RS20270	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS20280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM401_RS20290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM401_RS20295	COG0436	Aminotransferase
KM401_RS20315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM401_RS20335	COG2199	diguanylate cyclase activity
KM401_RS20340	COG0778	Nitroreductase
KM401_RS20365	COG1263	PTS System
KM401_RS20365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM401_RS20365	COG2190	(PTS) system
KM401_RS20370	COG3711	transcriptional antiterminator
KM401_RS20380	COG2188	Transcriptional regulator
KM401_RS20390	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM401_RS20415	COG1547	Domain of unknown function (DUF309)
KM401_RS20420	COG0456	acetyltransferase
KM401_RS20430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM401_RS20435	COG4086	secreted protein
KM401_RS20440	COG0561	phosphatase activity
KM401_RS20445	COG0697	spore germination
KM401_RS20460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_RS20485	COG0733	neurotransmitter:sodium symporter activity
KM401_RS20505	COG1686	Belongs to the peptidase S11 family
KM401_RS20510	COG1725	Transcriptional regulator
KM401_RS20515	COG1131	(ABC) transporter
KM401_RS20530	COG1846	Transcriptional regulator
KM401_RS20545	COG0598	Magnesium transport protein CorA
KM401_RS20570	COG4974	Belongs to the 'phage' integrase family
KM401_RS20580	COG0735	belongs to the Fur family
KM401_RS20585	COG1300	Membrane
KM401_RS20605	COG0667	Aldo Keto reductase
KM401_RS20610	COG0656	L-ascorbic acid biosynthetic process
KM401_RS20615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM401_RS20615	COG0456	acetyltransferase
KM401_RS20625	COG0737	Belongs to the 5'-nucleotidase family
KM401_RS20625	COG1525	nuclease
KM401_RS20625	COG4085	toxin activity
KM401_RS20635	COG0596	Alpha beta hydrolase
KM401_RS20640	COG2056	Na+-H+ antiporter family
KM401_RS20645	COG1609	Transcriptional regulator
KM401_RS20650	COG0456	acetyltransferase
KM401_RS20655	COG1073	alpha beta
KM401_RS20670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM401_RS20670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM401_RS20675	COG0307	riboflavin synthase, alpha
KM401_RS20700	COG4106	trans-aconitate 2-methyltransferase activity
KM401_RS20705	COG2226	methyltransferase
KM401_RS20705	COG1073	alpha beta
KM401_RS20720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM401_RS20730	COG1757	Na H antiporter
KM401_RS20735	COG0737	Belongs to the 5'-nucleotidase family
KM401_RS20745	COG1522	sequence-specific DNA binding
KM401_RS20765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM401_RS20775	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM401_RS20790	COG0300	oxidoreductase activity
KM401_RS20800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_RS20805	COG1760	l-serine dehydratase
KM401_RS20810	COG1760	l-serine dehydratase
KM401_RS20830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM401_RS20840	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM401_RS20845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS20860	COG1376	ErfK ybiS ycfS ynhG family protein
KM401_RS20865	COG4129	membrane
KM401_RS20870	COG1126	abc transporter atp-binding protein
KM401_RS20875	COG0765	amino acid transport
KM401_RS20880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM401_RS20895	COG2816	NAD+ diphosphatase activity
KM401_RS20900	COG0772	Belongs to the SEDS family
KM401_RS20905	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM401_RS20910	COG0022	dehydrogenase e1 component
KM401_RS20915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM401_RS20920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM401_RS20935	COG0280	phosphate acetyltransferase
KM401_RS20940	COG3290	protein histidine kinase activity
KM401_RS20940	COG3829	transcription factor binding
KM401_RS20950	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_RS20955	COG3093	addiction module antidote protein HigA
KM401_RS20965	COG0745	RESPONSE REGULATOR receiver
KM401_RS20970	COG0750	zinc metalloprotease
KM401_RS20975	COG0497	DNA recombination
KM401_RS20985	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM401_RS20995	COG0142	geranyltranstransferase activity
KM401_RS21020	COG1302	Protein conserved in bacteria
KM401_RS21025	COG0439	Biotin carboxylase
KM401_RS21030	COG0511	ligase activity, forming carbon-carbon bonds
KM401_RS21075	COG3854	ATPases associated with a variety of cellular activities
KM401_RS21100	COG0006	proline dipeptidase activity
KM401_RS21115	COG3872	metal-dependent enzyme
KM401_RS21125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM401_RS21145	COG0095	Lipoate-protein ligase
KM401_RS21150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_RS21155	COG1609	Transcriptional regulator
KM401_RS21165	COG2076	Multidrug Resistance protein
KM401_RS21170	COG2076	Multidrug Resistance protein
KM401_RS21210	COG1725	Transcriptional regulator
KM401_RS21240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM401_RS21295	COG4970	Tfp pilus assembly protein FimT
KM401_RS21305	COG1459	type II secretion system
KM401_RS21310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM401_RS21360	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM401_RS21365	COG0646	methionine synthase
KM401_RS21365	COG1410	methionine synthase
KM401_RS21370	COG0646	methionine synthase
KM401_RS21370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM401_RS21375	COG0626	cystathionine gamma-synthase activity
KM401_RS21380	COG0626	cystathionine gamma-synthase activity
KM401_RS21400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS21410	COG1940	carbohydrate kinase activity
KM401_RS21415	COG4483	Protein conserved in bacteria
KM401_RS21420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM401_RS21425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM401_RS21430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM401_RS21435	COG0704	Plays a role in the regulation of phosphate uptake
KM401_RS21445	COG0581	inorganic phosphate transmembrane transporter activity
KM401_RS21450	COG0573	inorganic phosphate transmembrane transporter activity
KM401_RS21455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM401_RS21460	COG0768	penicillin binding
KM401_RS21465	COG0477	Major facilitator Superfamily
KM401_RS21470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM401_RS21495	COG0735	belongs to the Fur family
KM401_RS21500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM401_RS21505	COG1121	(ABC) transporter
KM401_RS21510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS21540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM401_RS21545	COG2384	SAM-dependent methyltransferase
KM401_RS21550	COG2010	Cytochrome c
KM401_RS21555	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM401_RS21560	COG0358	DNA primase activity
KM401_RS21575	COG0517	IMP dehydrogenase activity
KM401_RS21590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM401_RS21595	COG0295	cytidine deaminase activity
KM401_RS21600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM401_RS21610	COG1480	7TM receptor with intracellular HD hydrolase
KM401_RS21615	COG1702	phosphate starvation-inducible protein PhoH
KM401_RS21630	COG1610	YqeY-like protein
KM401_RS21635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM401_RS21640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM401_RS21645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM401_RS21675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM401_RS21680	COG1733	regulation of RNA biosynthetic process
KM401_RS21705	COG1466	dna polymerase III delta subunit
KM401_RS21715	COG0658	competence protein
KM401_RS21715	COG2333	competence protein COMEC
KM401_RS21720	COG2131	deaminase
KM401_RS21725	COG1555	photosystem II stabilization
KM401_RS21725	COG1596	polysaccharide export
KM401_RS21730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM401_RS21735	COG2226	methyltransferase
KM401_RS21740	COG0799	negative regulation of ribosome biogenesis
KM401_RS21745	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM401_RS21755	COG1534	Rna-binding protein
KM401_RS21765	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM401_RS21770	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM401_RS21795	COG1595	DNA-templated transcription, initiation
KM401_RS21805	COG0778	Nitroreductase
KM401_RS21810	COG2357	RelA SpoT domain protein
KM401_RS21820	COG1785	Belongs to the alkaline phosphatase family
KM401_RS21830	COG2267	carboxylic ester hydrolase activity
KM401_RS21865	COG1404	Belongs to the peptidase S8 family
KM401_RS21870	COG3186	Phenylalanine-4-hydroxylase
KM401_RS21885	COG2259	Doxx family
KM401_RS21925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_RS21935	COG1012	belongs to the aldehyde dehydrogenase family
KM401_RS21935	COG1454	alcohol dehydrogenase
KM401_RS21940	COG0626	cystathionine gamma-synthase activity
KM401_RS21945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM401_RS21970	COG0768	penicillin binding
KM401_RS21985	COG0826	peptidase U32
KM401_RS21990	COG0826	peptidase U32
KM401_RS21995	COG4122	O-methyltransferase activity
KM401_RS22000	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM401_RS22020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM401_RS22030	COG0628	permease
KM401_RS22050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM401_RS22060	COG0482	sulfurtransferase activity
KM401_RS22065	COG1104	cysteine desulfurase activity
KM401_RS22070	COG1959	2 iron, 2 sulfur cluster binding
KM401_RS22075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM401_RS22085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM401_RS22110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM401_RS22120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM401_RS22120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM401_RS22125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM401_RS22130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM401_RS22130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM401_RS22140	COG2244	polysaccharide biosynthetic process
KM401_RS22145	COG2323	membrane
KM401_RS22155	COG1862	Preprotein translocase
KM401_RS22185	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM401_RS22195	COG0697	spore germination
KM401_RS22200	COG0697	spore germination
KM401_RS22205	COG0640	Transcriptional regulator
KM401_RS22230	COG0157	Belongs to the NadC ModD family
KM401_RS22235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM401_RS22240	COG1104	cysteine desulfurase activity
KM401_RS22245	COG1827	regulation of RNA biosynthetic process
KM401_RS22250	COG2258	MOSC domain
KM401_RS22255	COG0077	Prephenate dehydratase
KM401_RS22260	COG0577	efflux transmembrane transporter activity
KM401_RS22265	COG0577	efflux transmembrane transporter activity
KM401_RS22270	COG1136	(ABC) transporter
KM401_RS22280	COG0745	RESPONSE REGULATOR receiver
KM401_RS22285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM401_RS22290	COG3290	protein histidine kinase activity
KM401_RS22300	COG2868	ribosomal protein
KM401_RS22310	COG1530	ribonuclease E activity
KM401_RS22315	COG1994	Peptidase M50
KM401_RS22320	COG0739	heme binding
KM401_RS22325	COG2894	cell division
KM401_RS22345	COG1077	Cell shape determining protein MreB Mrl
KM401_RS22365	COG0285	dihydrofolate synthase activity
KM401_RS22370	COG0525	valine-tRNA ligase activity
KM401_RS22380	COG1388	LysM domain
KM401_RS22390	COG0113	porphobilinogen synthase activity
KM401_RS22395	COG1587	Uroporphyrinogen-III synthase
KM401_RS22405	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM401_RS22415	COG1846	Transcriptional regulator
KM401_RS22420	COG1764	response to oxidative stress
KM401_RS22435	COG1067	ATP-dependent peptidase activity
KM401_RS22435	COG0470	DNA polymerase III
KM401_RS22480	COG0622	Phosphoesterase
KM401_RS22495	COG5401	PFAM Sporulation and spore germination
KM401_RS22515	COG1309	transcriptional regulator
KM401_RS22530	COG2197	response regulator
KM401_RS22535	COG2233	PERMEase
KM401_RS22545	COG0402	S-adenosylhomocysteine deaminase activity
KM401_RS22550	COG0402	S-adenosylhomocysteine deaminase activity
KM401_RS22560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM401_RS22570	COG0444	Belongs to the ABC transporter superfamily
KM401_RS22575	COG4608	Belongs to the ABC transporter superfamily
KM401_RS22580	COG3275	phosphorelay sensor kinase activity
KM401_RS22585	COG3279	Response regulator of the LytR AlgR family
KM401_RS22600	COG1983	PspC domain protein
KM401_RS22605	COG1396	sequence-specific DNA binding
KM401_RS22610	COG0697	spore germination
KM401_RS22620	COG1959	2 iron, 2 sulfur cluster binding
KM401_RS22625	COG1668	transmembrane transport
KM401_RS22630	COG4152	abc transporter atp-binding protein
KM401_RS22635	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM401_RS22645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM401_RS22650	COG1876	peptidase activity
KM401_RS22655	COG0824	Thioesterase
KM401_RS22660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM401_RS22665	COG1053	succinate dehydrogenase
KM401_RS22670	COG2009	succinate dehydrogenase
KM401_RS22675	COG1719	4-vinyl reductase, 4VR
KM401_RS22685	COG3118	belongs to the thioredoxin family
KM401_RS22690	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM401_RS22695	COG2086	electron transfer activity
KM401_RS22700	COG1024	Enoyl-CoA hydratase
KM401_RS22710	COG0318	PFAM AMP-dependent synthetase and ligase
KM401_RS22730	COG2318	DinB family
KM401_RS22760	COG1131	(ABC) transporter
KM401_RS22765	COG2205	protein histidine kinase activity
KM401_RS22770	COG0745	RESPONSE REGULATOR receiver
KM401_RS22780	COG4895	conserved protein (DUF2196)
KM401_RS22785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM401_RS22800	COG4509	Sortase family
KM401_RS22805	COG1120	ATPase activity
KM401_RS22820	COG5386	Cell surface protein
KM401_RS22830	COG5386	Cell surface protein
KM401_RS22835	COG1114	Component of the transport system for branched-chain amino acids
KM401_RS22840	COG1187	pseudouridine synthase activity
KM401_RS22850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM401_RS22850	COG1796	DNA polymerase
KM401_RS22855	COG1286	toxin biosynthetic process
KM401_RS22900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM401_RS22910	COG1418	mRNA catabolic process
KM401_RS22935	COG2814	Major facilitator Superfamily
KM401_RS22940	COG1566	PFAM secretion protein HlyD family protein
KM401_RS22945	COG1309	transcriptional regulator
KM401_RS22950	COG1363	Peptidase, m42
KM401_RS22975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM401_RS22985	COG1484	DNA-dependent DNA replication
KM401_RS22990	COG3611	Membrane attachment protein
KM401_RS23000	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM401_RS23005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM401_RS23010	COG0237	dephospho-CoA kinase activity
KM401_RS23015	COG1971	Probably functions as a manganese efflux pump
KM401_RS23025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM401_RS23025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM401_RS23030	COG5002	protein histidine kinase activity
KM401_RS23035	COG0745	RESPONSE REGULATOR receiver
KM401_RS23055	COG0538	isocitrate dehydrogenase activity
KM401_RS23060	COG0372	Belongs to the citrate synthase family
KM401_RS23070	COG0628	permease
KM401_RS23075	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM401_RS23100	COG1725	Transcriptional regulator
KM401_RS23105	COG0281	malic enzyme
KM401_RS23110	COG0587	DNA-directed DNA polymerase activity
KM401_RS23125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM401_RS23145	COG4109	DRTGG domain
KM401_RS23160	COG0006	proline dipeptidase activity
KM401_RS23200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS23205	COG0662	Cupin 2, conserved barrel domain protein
KM401_RS23215	COG1476	TRANSCRIPTIONal
KM401_RS23230	COG1028	Short-chain dehydrogenase reductase Sdr
KM401_RS23235	COG0589	response to stress
KM401_RS23275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS23295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM401_RS23300	COG0827	DNA restriction-modification system
KM401_RS23305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM401_RS23310	COG3874	Sporulation protein YtfJ
KM401_RS23325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM401_RS23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM401_RS23350	COG1104	cysteine desulfurase activity
KM401_RS23360	COG0583	DNA-binding transcription factor activity
KM401_RS23365	COG0697	spore germination
KM401_RS23375	COG1956	GAF domain-containing protein
KM401_RS23380	COG0626	cystathionine gamma-synthase activity
KM401_RS23410	COG1595	DNA-templated transcription, initiation
KM401_RS23420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM401_RS23425	COG0454	-acetyltransferase
KM401_RS23430	COG0517	IMP dehydrogenase activity
KM401_RS23435	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM401_RS23445	COG0745	RESPONSE REGULATOR receiver
KM401_RS23455	COG0666	response to abiotic stimulus
KM401_RS23490	COG1609	Transcriptional regulator
KM401_RS23495	COG4851	CamS sex pheromone cAM373 precursor
KM401_RS23500	COG3118	belongs to the thioredoxin family
KM401_RS23510	COG2309	aminopeptidase activity
KM401_RS23530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS23545	COG1674	ftsk spoiiie
KM401_RS23555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM401_RS23560	COG4848	Belongs to the UPF0354 family
KM401_RS23565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_RS23570	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM401_RS23575	COG1363	Peptidase, m42
KM401_RS23585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS23600	COG0510	thiamine kinase activity
KM401_RS23605	COG1523	belongs to the glycosyl hydrolase 13 family
KM401_RS23620	COG1349	DNA-binding transcription factor activity
KM401_RS23625	COG1187	pseudouridine synthase activity
KM401_RS23630	COG2244	polysaccharide biosynthetic process
KM401_RS23635	COG2081	HI0933 family
KM401_RS23640	COG2814	Major facilitator Superfamily
KM401_RS23650	COG3832	glyoxalase III activity
KM401_RS23670	COG1329	Transcriptional regulator
KM401_RS23680	COG4975	Glucose uptake
KM401_RS23695	COG0314	molybdopterin synthase activity
KM401_RS23700	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM401_RS23705	COG0303	'Molybdopterin
KM401_RS23715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM401_RS23740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM401_RS23750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM401_RS23795	COG2814	Major facilitator Superfamily
KM401_RS23800	COG0475	glutathione-regulated potassium exporter activity
KM401_RS23805	COG0490	domain, Protein
KM401_RS23810	COG0582	viral genome integration into host DNA
KM401_RS23820	COG1136	(ABC) transporter
KM401_RS23840	COG1242	4 iron, 4 sulfur cluster binding
KM401_RS23845	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM401_RS23850	COG1131	(ABC) transporter
KM401_RS23860	COG1794	racemase activity, acting on amino acids and derivatives
KM401_RS23880	COG2267	carboxylic ester hydrolase activity
KM401_RS23885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM401_RS23890	COG0671	phosphoesterase, PA-phosphatase related
KM401_RS23895	COG0438	transferase activity, transferring glycosyl groups
KM401_RS23905	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM401_RS23960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM401_RS23965	COG5002	protein histidine kinase activity
KM401_RS23970	COG4191	Histidine kinase
KM401_RS23975	COG2267	carboxylic ester hydrolase activity
KM401_RS23995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM401_RS24000	COG1116	anion transmembrane transporter activity
KM401_RS24005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM401_RS24030	COG0494	nUDIX hydrolase
KM401_RS24065	COG0288	reversible hydration of carbon dioxide
KM401_RS24070	COG1271	oxidase subunit
KM401_RS24075	COG1294	oxidase, subunit
KM401_RS24095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS24120	COG1842	Phage shock protein A
KM401_RS24150	COG5002	protein histidine kinase activity
KM401_RS24155	COG0745	RESPONSE REGULATOR receiver
KM401_RS24185	COG1597	lipid kinase activity
KM401_RS24220	COG0586	Pfam SNARE associated Golgi protein
KM401_RS24230	COG0577	efflux transmembrane transporter activity
KM401_RS24235	COG1136	(ABC) transporter
KM401_RS24240	COG3708	Transcriptional regulator
KM401_RS24240	COG2207	Transcriptional regulator
KM401_RS24245	COG0745	RESPONSE REGULATOR receiver
KM401_RS24250	COG2205	protein histidine kinase activity
KM401_RS24260	COG0577	efflux transmembrane transporter activity
KM401_RS24265	COG1136	(ABC) transporter
KM401_RS24285	COG2188	Transcriptional regulator
KM401_RS24305	COG3964	amidohydrolase
KM401_RS24335	COG4948	Mandelate Racemase Muconate Lactonizing
KM401_RS24345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM401_RS24350	COG0596	Alpha beta hydrolase
KM401_RS24355	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM401_RS24360	COG1169	isochorismate synthase
KM401_RS24365	COG1575	Belongs to the MenA family. Type 1 subfamily
KM401_RS24370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM401_RS24390	COG0058	SHG alpha-glucan phosphorylase activity
KM401_RS24395	COG0297	glycogen (starch) synthase activity
KM401_RS24400	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM401_RS24515	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM401_RS24550	COG1285	pathogenesis
KM401_RS24555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM401_RS24565	COG0166	Belongs to the GPI family
KM401_RS24570	COG2155	Conserved Protein
KM401_RS24575	COG1098	S1 RNA binding domain
KM401_RS24580	COG0436	Aminotransferase
KM401_RS24585	COG1522	sequence-specific DNA binding
KM401_RS24590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM401_RS24595	COG2267	carboxylic ester hydrolase activity
KM401_RS24605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM401_RS24625	COG5018	Exonuclease
KM401_RS24630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM401_RS24650	COG2050	protein possibly involved in aromatic compounds catabolism
KM401_RS24660	COG1268	BioY protein
KM401_RS24670	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM401_RS24675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM401_RS24690	COG3584	3D domain protein
KM401_RS24705	COG1252	NADH dehydrogenase
KM401_RS24720	COG3708	Transcriptional regulator
KM401_RS24735	COG1683	Conserved Protein
KM401_RS24755	COG0316	Belongs to the HesB IscA family
KM401_RS24770	COG1252	NADH dehydrogenase
KM401_RS24785	COG0390	transport system, permease component
KM401_RS24790	COG2824	Alkylphosphonate utilization operon protein PhnA
KM401_RS24830	COG4837	Protein of unknown function (DUF1462)
KM401_RS24835	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM401_RS24845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM401_RS24850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM401_RS24860	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM401_RS24865	COG0647	UMP catabolic process
KM401_RS24875	COG2445	Protein of unknown function DUF86
KM401_RS24880	COG1494	fructose-1,6-bisphosphatase
KM401_RS24895	COG4470	Protein conserved in bacteria
KM401_RS24905	COG0789	Transcriptional regulator
KM401_RS24910	COG4377	Putative membrane peptidase family (DUF2324)
KM401_RS24935	COG0739	heme binding
KM401_RS24945	COG3377	Domain of unknown function (DUF1805)
KM401_RS24950	COG0737	Belongs to the 5'-nucleotidase family
KM401_RS24955	COG1695	Transcriptional regulator
KM401_RS24965	COG0719	Fe-S assembly protein
KM401_RS24970	COG0822	iron-sulfur transferase activity
KM401_RS24975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM401_RS24980	COG0719	Fe-S assembly protein
KM401_RS24985	COG0396	ATPase activity
KM401_RS24990	COG1464	Belongs to the NlpA lipoprotein family
KM401_RS24995	COG1464	Belongs to the NlpA lipoprotein family
KM401_RS25000	COG2011	ABC-type metal ion transport system permease component
KM401_RS25005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM401_RS25015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM401_RS25020	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM401_RS25030	COG1393	Belongs to the ArsC family
KM401_RS25075	COG0039	L-malate dehydrogenase activity
KM401_RS25100	COG1309	transcriptional regulator
KM401_RS25105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM401_RS25110	COG1960	acyl-CoA dehydrogenase activity
KM401_RS25115	COG0183	Belongs to the thiolase family
KM401_RS25120	COG1024	Enoyl-CoA hydratase
KM401_RS25120	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM401_RS25130	COG1686	Belongs to the peptidase S11 family
KM401_RS25145	COG0011	TIGRFAM Protein of
KM401_RS25150	COG0840	transmembrane signaling receptor activity
KM401_RS25170	COG2814	Major facilitator Superfamily
KM401_RS25175	COG0531	amino acid
KM401_RS25185	COG0706	membrane insertase activity
KM401_RS25195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM401_RS25230	COG0586	Pfam SNARE associated Golgi protein
KM401_RS25240	COG1376	ErfK ybiS ycfS ynhG family protein
KM401_RS25245	COG0745	RESPONSE REGULATOR receiver
KM401_RS25250	COG5002	protein histidine kinase activity
KM401_RS25275	COG2151	metal-sulfur cluster biosynthetic enzyme
KM401_RS25280	COG3227	Zinc metalloprotease (Elastase)
KM401_RS25285	COG1741	Belongs to the pirin family
KM401_RS25300	COG0475	glutathione-regulated potassium exporter activity
KM401_RS25305	COG0490	domain, Protein
KM401_RS25310	COG1115	amino acid carrier protein
KM401_RS25315	COG0783	Belongs to the Dps family
KM401_RS25330	COG1611	Belongs to the LOG family
KM401_RS25350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS25355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS25360	COG1115	amino acid carrier protein
KM401_RS25365	COG1115	amino acid carrier protein
KM401_RS25370	COG2910	NAD(P)H-binding
KM401_RS25385	COG0656	L-ascorbic acid biosynthetic process
KM401_RS25390	COG2814	Major facilitator Superfamily
KM401_RS25395	COG1733	regulation of RNA biosynthetic process
KM401_RS25405	COG1252	NADH dehydrogenase
KM401_RS25410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM401_RS25415	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM401_RS25425	COG3290	protein histidine kinase activity
KM401_RS25425	COG0840	transmembrane signaling receptor activity
KM401_RS25435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM401_RS25440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM401_RS25455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM401_RS25510	COG0557	exoribonuclease II activity
KM401_RS25515	COG1647	Serine aminopeptidase, S33
KM401_RS25520	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM401_RS25525	COG1346	cytolysis
KM401_RS25630	COG4695	Portal protein
KM401_RS25655	COG4974	Belongs to the 'phage' integrase family
KM401_RS25665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM401_RS25670	COG0149	triose-phosphate isomerase activity
KM401_RS25680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM401_RS25695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM401_RS25720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM401_RS25735	COG2323	membrane
KM401_RS25740	COG0740	serine-type endopeptidase activity
KM401_RS25745	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM401_RS25755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM401_RS25765	COG1051	belongs to the nudix hydrolase family
KM401_RS25775	COG0492	ferredoxin-NADP+ reductase activity
KM401_RS25780	COG0457	Tetratricopeptide repeat
KM401_RS25785	COG0110	maltose O-acetyltransferase activity
KM401_RS25805	COG1950	PFAM Membrane protein of
KM401_RS25815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM401_RS25820	COG0556	nucleotide-excision repair
KM401_RS25840	COG0789	Transcriptional regulator
KM401_RS25865	COG2855	membrane
KM401_RS25870	COG0583	DNA-binding transcription factor activity
KM401_RS25880	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM401_RS25885	COG0488	(ABC) transporter
KM401_RS25895	COG1132	(ABC) transporter
KM401_RS25900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM401_RS25905	COG0793	Belongs to the peptidase S41A family
KM401_RS25905	COG3409	Peptidoglycan-binding domain 1 protein
KM401_RS25910	COG2177	Part of the ABC transporter FtsEX involved in
KM401_RS25915	COG2884	Cell division ATP-binding protein ftsE
KM401_RS25930	COG0653	protein targeting
KM401_RS25935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM401_RS25940	COG1278	Cold shock
KM401_RS25945	COG1040	competence protein
KM401_RS25950	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM401_RS25955	COG0791	NLP P60 protein
KM401_RS25955	COG1388	LysM domain
KM401_RS25960	COG1733	regulation of RNA biosynthetic process
KM401_RS25965	COG1307	EDD domain protein, DegV family
KM401_RS25970	COG1739	Uncharacterized protein family UPF0029
KM401_RS25975	COG1316	TRANSCRIPTIONal
KM401_RS25980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM401_RS25985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM401_RS25990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM401_RS26000	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM401_RS26000	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM401_RS26015	COG3394	polysaccharide catabolic process
KM401_RS26020	COG1486	melibiose metabolic process
KM401_RS26025	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM401_RS26030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM401_RS26040	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM401_RS26045	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM401_RS26050	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM401_RS26060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM401_RS26065	COG1301	dicarboxylic acid transport
KM401_RS26075	COG0346	lactoylglutathione lyase activity
KM401_RS26080	COG1511	domain protein
KM401_RS26085	COG0583	DNA-binding transcription factor activity
KM401_RS26090	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM401_RS26105	COG1271	oxidase subunit
KM401_RS26110	COG1294	oxidase, subunit
KM401_RS26115	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM401_RS26135	COG2389	metal-binding protein
KM401_RS26145	COG1368	sulfuric ester hydrolase activity
KM401_RS26160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM401_RS26170	COG1215	transferase activity, transferring glycosyl groups
KM401_RS26175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM401_RS26180	COG1388	LysM domain
KM401_RS26180	COG3584	3D domain protein
KM401_RS26205	COG4715	Zinc finger, swim domain protein
KM401_RS26210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM401_RS26250	COG0577	efflux transmembrane transporter activity
KM401_RS26255	COG1136	(ABC) transporter
KM401_RS26290	COG5002	protein histidine kinase activity
KM401_RS26295	COG0745	RESPONSE REGULATOR receiver
KM401_RS26300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM401_RS26320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM401_RS26325	COG1134	teichoic acid transport
KM401_RS26330	COG1682	transport, permease protein
KM401_RS26335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM401_RS26380	COG1609	Transcriptional regulator
KM401_RS26395	COG0739	heme binding
KM401_RS26415	COG2385	sporulation resulting in formation of a cellular spore
KM401_RS26430	COG4836	Membrane
KM401_RS26435	COG1007	ATP synthesis coupled electron transport
KM401_RS26440	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM401_RS26445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM401_RS26455	COG0839	Belongs to the complex I subunit 6 family
KM401_RS26470	COG0649	NAD binding
KM401_RS26475	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM401_RS26490	COG3300	MHYT domain
KM401_RS26490	COG5001	Diguanylate cyclase
KM401_RS26540	COG0356	it plays a direct role in the translocation of protons across the membrane
KM401_RS26575	COG0698	ribose 5-phosphate isomerase
KM401_RS26585	COG2190	(PTS) system
KM401_RS26590	COG2259	Doxx family
KM401_RS26595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM401_RS26610	COG0009	L-threonylcarbamoyladenylate synthase
KM401_RS26625	COG2890	protein-(glutamine-N5) methyltransferase activity
KM401_RS26645	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM401_RS26650	COG1494	fructose-1,6-bisphosphatase
KM401_RS26670	COG4821	SIS domain
KM401_RS26680	COG3343	RNA polymerase activity
KM401_RS26690	COG1960	acyl-CoA dehydrogenase activity
KM401_RS26695	COG1960	acyl-CoA dehydrogenase activity
KM401_RS26700	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM401_RS26705	COG0183	Belongs to the thiolase family
KM401_RS26710	COG2181	nitrate reductase activity
KM401_RS26710	COG0247	lactate metabolic process
KM401_RS26715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM401_RS26725	COG3300	MHYT domain
KM401_RS26725	COG5001	Diguanylate cyclase
KM401_RS26745	COG2197	response regulator
KM401_RS26750	COG4585	Histidine kinase
KM401_RS26755	COG0842	Transport permease protein
KM401_RS26760	COG1131	(ABC) transporter
KM401_RS26765	COG0024	Methionine aminopeptidase
KM401_RS26775	COG2234	aminopeptidase activity
KM401_RS26795	COG1595	DNA-templated transcription, initiation
KM401_RS26800	COG0018	arginyl-trna synthetase
KM401_RS26805	COG4506	Protein conserved in bacteria
KM401_RS26810	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM401_RS26825	COG0010	Belongs to the arginase family
KM401_RS26835	COG2814	Major facilitator Superfamily
KM401_RS26840	COG0789	Transcriptional regulator
KM401_RS26845	COG0584	glycerophosphoryl diester phosphodiesterase
KM401_RS26850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM401_RS26860	COG1994	Peptidase M50
KM401_RS26870	COG1078	dGTPase activity
KM401_RS26875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM401_RS26880	COG1120	ATPase activity
KM401_RS26885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM401_RS26910	COG0095	Lipoate-protein ligase
KM401_RS26915	COG0280	phosphate acetyltransferase
KM401_RS26930	COG3773	Cell wall hydrolase
KM401_RS26940	COG2363	Small membrane protein
KM401_RS26950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM401_RS26955	COG2233	PERMEase
KM401_RS26960	COG0561	phosphatase activity
KM401_RS26965	COG2814	Major facilitator Superfamily
KM401_RS26975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM401_RS26980	COG1131	(ABC) transporter
KM401_RS26985	COG2755	lipolytic protein G-D-S-L family
KM401_RS26990	COG1609	Transcriptional regulator
KM401_RS27000	COG0460	homoserine dehydrogenase
KM401_RS27010	COG2873	o-acetylhomoserine
KM401_RS27020	COG1011	Hydrolase
KM401_RS27025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM401_RS27035	COG2197	response regulator
KM401_RS27045	COG0351	phosphomethylpyrimidine kinase
KM401_RS27050	COG3706	GGDEF domain
KM401_RS27055	COG2879	small protein
KM401_RS27060	COG1966	Carbon starvation protein
KM401_RS27065	COG3279	Response regulator of the LytR AlgR family
KM401_RS27070	COG0477	Major facilitator Superfamily
KM401_RS27095	COG0840	transmembrane signaling receptor activity
KM401_RS27105	COG1607	acyl-coa hydrolase
KM401_RS27120	COG0488	(ABC) transporter
KM401_RS27140	COG0463	Glycosyl transferase, family 2
KM401_RS27145	COG1309	transcriptional regulator
KM401_RS27150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM401_RS27155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM401_RS27155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM401_RS27160	COG0628	permease
KM401_RS27175	COG3279	Response regulator of the LytR AlgR family
KM401_RS27180	COG3275	phosphorelay sensor kinase activity
KM401_RS27185	COG2814	Major facilitator Superfamily
KM401_RS27190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM401_RS27195	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM401_RS27200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM401_RS27220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM401_RS27225	COG1272	protein, Hemolysin III
KM401_RS27245	COG0516	GMP reductase activity
KM401_RS27250	COG1164	Oligoendopeptidase f
KM401_RS27270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM401_RS27275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM401_RS27280	COG4853	Protein conserved in bacteria
KM401_RS27285	COG4863	YycH protein
KM401_RS27290	COG5002	protein histidine kinase activity
KM401_RS27295	COG0745	RESPONSE REGULATOR receiver
KM401_RS27325	COG0305	Participates in initiation and elongation during chromosome replication
KM401_RS27335	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM401_RS27340	COG4241	membrane
KM401_RS27350	COG0629	single-stranded DNA binding
KM401_RS27360	COG0012	GTP binding
KM401_RS27365	COG4481	Protein conserved in bacteria
KM401_RS27370	COG0668	transmembrane transport
KM401_RS27380	COG1475	DNA binding
KM401_RS27385	COG1192	Involved in chromosome partitioning
KM401_RS27410	COG1847	R3H domain protein
KM401_RS27415	COG0706	membrane insertase activity
KM401_RS27425	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM401_RS27580	COG0791	NLP P60 protein
KM401_RS27580	COG0741	lytic transglycosylase activity
KM401_RS27700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM401_RS27710	COG4166	transmembrane transport
KM401_RS27755	COG1280	lysine exporter protein (LysE YggA)
KM401_RS27780	COG0681	Belongs to the peptidase S26 family
KM401_RS27855	COG1309	transcriptional regulator
KM401_RS27860	COG1683	Conserved Protein
KM401_RS27910	COG1192	Involved in chromosome partitioning