locus-tag	class	description
M1C60_RS00010	COG0592	DNA-directed DNA polymerase activity
M1C60_RS00015	COG2501	S4 domain
M1C60_RS00025	COG0187	DNA topoisomerase II activity
M1C60_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1C60_RS00065	COG0516	GMP reductase activity
M1C60_RS00065	COG0517	IMP dehydrogenase activity
M1C60_RS00070	COG1686	Belongs to the peptidase S11 family
M1C60_RS00100	COG1428	Deoxynucleoside kinase
M1C60_RS00105	COG1428	Deoxynucleoside kinase
M1C60_RS00110	COG1335	isochorismatase
M1C60_RS00115	COG0590	tRNA wobble adenosine to inosine editing
M1C60_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1C60_RS00180	COG1982	Orn Lys Arg decarboxylase major
M1C60_RS00190	COG0470	DNA polymerase III
M1C60_RS00195	COG1774	PSP1 C-terminal conserved region
M1C60_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M1C60_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M1C60_RS00220	COG2002	toxin-antitoxin pair type II binding
M1C60_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_RS00230	COG0084	hydrolase, TatD family'
M1C60_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1C60_RS00250	COG4466	Protein conserved in bacteria
M1C60_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M1C60_RS00270	COG0251	oxidation-reduction process
M1C60_RS00305	COG2002	toxin-antitoxin pair type II binding
M1C60_RS00315	COG3956	TIGRFAM MazG family protein
M1C60_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1C60_RS00340	COG1098	S1 RNA binding domain
M1C60_RS00355	COG2208	phosphoserine phosphatase activity
M1C60_RS00360	COG0037	tRNA processing
M1C60_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M1C60_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1C60_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1C60_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1C60_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
M1C60_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1C60_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M1C60_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1C60_RS00420	COG1396	sequence-specific DNA binding
M1C60_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1C60_RS00455	COG3880	PFAM UvrB UvrC protein
M1C60_RS00465	COG0542	response to heat
M1C60_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M1C60_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
M1C60_RS00500	COG1045	serine acetyltransferase
M1C60_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1C60_RS00520	COG3688	RNA-binding protein containing a PIN domain
M1C60_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1C60_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
M1C60_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
M1C60_RS00565	COG2813	Specifically methylates the guanine in position
M1C60_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M1C60_RS00580	COG1358	cellular component organization or biogenesis
M1C60_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
M1C60_RS00710	COG0201	protein transport
M1C60_RS00720	COG0024	Methionine aminopeptidase
M1C60_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M1C60_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1C60_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS00795	COG0489	protein tyrosine kinase activity
M1C60_RS00805	COG2194	sulfuric ester hydrolase activity
M1C60_RS00810	COG0726	polysaccharide deacetylase
M1C60_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M1C60_RS00895	COG4856	YbbR-like protein
M1C60_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1C60_RS00915	COG0596	Alpha beta hydrolase
M1C60_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M1C60_RS00940	COG1506	peptidase
M1C60_RS00940	COG4946	Tricorn protease homolog
M1C60_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
M1C60_RS00975	COG2011	ABC-type metal ion transport system permease component
M1C60_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1C60_RS00985	COG1464	Belongs to the NlpA lipoprotein family
M1C60_RS00990	COG0604	alcohol dehydrogenase
M1C60_RS01000	COG0277	FAD linked oxidase domain protein
M1C60_RS01005	COG2271	Major facilitator Superfamily
M1C60_RS01015	COG2814	Major facilitator Superfamily
M1C60_RS01030	COG0601	transmembrane transport
M1C60_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_RS01040	COG0444	Belongs to the ABC transporter superfamily
M1C60_RS01045	COG4608	Belongs to the ABC transporter superfamily
M1C60_RS01050	COG4166	transmembrane transport
M1C60_RS01060	COG2207	Transcriptional regulator
M1C60_RS01075	COG4166	transmembrane transport
M1C60_RS01080	COG4166	transmembrane transport
M1C60_RS01085	COG0656	L-ascorbic acid biosynthetic process
M1C60_RS01105	COG4149	molybdate abc transporter
M1C60_RS01115	COG1910	domain protein
M1C60_RS01125	COG0583	DNA-binding transcription factor activity
M1C60_RS01130	COG0697	spore germination
M1C60_RS01145	COG0204	Acyl-transferase
M1C60_RS01155	COG1609	Transcriptional regulator
M1C60_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS01175	COG0084	hydrolase, TatD family'
M1C60_RS01180	COG5298	Protein conserved in bacteria
M1C60_RS01205	COG0488	(ABC) transporter
M1C60_RS01220	COG0747	negative chemotaxis
M1C60_RS01225	COG0601	transmembrane transport
M1C60_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_RS01235	COG0444	Belongs to the ABC transporter superfamily
M1C60_RS01240	COG4608	Belongs to the ABC transporter superfamily
M1C60_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
M1C60_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1C60_RS01290	COG2814	Major facilitator Superfamily
M1C60_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1C60_RS01310	COG4294	response to UV
M1C60_RS01315	COG0705	Rhomboid family
M1C60_RS01315	COG0457	Tetratricopeptide repeat
M1C60_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1C60_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1C60_RS01335	COG0864	Transcriptional regulator
M1C60_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
M1C60_RS01345	COG2183	response to ionizing radiation
M1C60_RS01440	COG0802	atpase or kinase
M1C60_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
M1C60_RS01450	COG0456	acetyltransferase
M1C60_RS01460	COG0488	(ABC) transporter
M1C60_RS01475	COG1266	CAAX protease self-immunity
M1C60_RS01495	COG2252	PERMEase
M1C60_RS01535	COG2226	methyltransferase
M1C60_RS01580	COG1968	undecaprenyl-diphosphatase activity
M1C60_RS01595	COG2205	protein histidine kinase activity
M1C60_RS01600	COG0745	RESPONSE REGULATOR receiver
M1C60_RS01625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M1C60_RS01630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1C60_RS01635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1C60_RS01645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1C60_RS01660	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M1C60_RS01670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1C60_RS01680	COG0151	Belongs to the GarS family
M1C60_RS01705	COG0210	DNA helicase
M1C60_RS01715	COG4851	CamS sex pheromone cAM373 precursor
M1C60_RS01735	COG1335	isochorismatase
M1C60_RS01740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1C60_RS01745	COG2011	ABC-type metal ion transport system permease component
M1C60_RS01750	COG1464	Belongs to the NlpA lipoprotein family
M1C60_RS01770	COG1846	Transcriptional regulator
M1C60_RS01795	COG1597	lipid kinase activity
M1C60_RS01800	COG0546	phosphoglycolate phosphatase activity
M1C60_RS01805	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1C60_RS01815	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS01820	COG2076	Multidrug Resistance protein
M1C60_RS01825	COG2309	aminopeptidase activity
M1C60_RS01840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS01845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1C60_RS01850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1C60_RS01860	COG4807	Protein conserved in bacteria
M1C60_RS01885	COG1757	Na H antiporter
M1C60_RS01890	COG1473	amidohydrolase
M1C60_RS01905	COG0450	alkyl hydroperoxide reductase
M1C60_RS01925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS01930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS01935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS01950	COG0166	Belongs to the GPI family
M1C60_RS01985	COG5002	protein histidine kinase activity
M1C60_RS02005	COG3541	Predicted nucleotidyltransferase
M1C60_RS02010	COG2814	Major facilitator Superfamily
M1C60_RS02015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_RS02015	COG0723	plastoquinol--plastocyanin reductase activity
M1C60_RS02025	COG0765	amino acid transport
M1C60_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_RS02040	COG0840	transmembrane signaling receptor activity
M1C60_RS02045	COG0840	transmembrane signaling receptor activity
M1C60_RS02050	COG0366	Alpha amylase catalytic
M1C60_RS02055	COG1263	PTS System
M1C60_RS02055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_RS02055	COG2190	(PTS) system
M1C60_RS02085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
M1C60_RS02100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_RS02110	COG1116	anion transmembrane transporter activity
M1C60_RS02115	COG0488	(ABC) transporter
M1C60_RS02160	COG2270	Major facilitator Superfamily
M1C60_RS02175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1C60_RS02190	COG2310	stress, protein
M1C60_RS02195	COG2310	stress, protein
M1C60_RS02200	COG2310	stress, protein
M1C60_RS02205	COG0861	Integral membrane protein TerC family
M1C60_RS02215	COG3853	Toxic anion resistance protein (TelA)
M1C60_RS02230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1C60_RS02240	COG1295	ribonuclease BN
M1C60_RS02245	COG2217	Heavy metal translocating P-type atpase
M1C60_RS02250	COG0697	spore germination
M1C60_RS02270	COG0586	Pfam SNARE associated Golgi protein
M1C60_RS02285	COG3871	stress protein (general stress protein 26)
M1C60_RS02290	COG0387	Pfam Sodium calcium exchanger
M1C60_RS02300	COG0535	radical SAM domain protein
M1C60_RS02325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M1C60_RS02330	COG0582	viral genome integration into host DNA
M1C60_RS02340	COG1396	sequence-specific DNA binding
M1C60_RS02360	COG1396	sequence-specific DNA binding
M1C60_RS02395	COG1484	DNA-dependent DNA replication
M1C60_RS02625	COG0101	tRNA pseudouridine synthase activity
M1C60_RS02635	COG3829	transcription factor binding
M1C60_RS02645	COG0833	amino acid
M1C60_RS02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1C60_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_RS02680	COG1263	PTS System
M1C60_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_RS02700	COG0463	Glycosyl transferase, family 2
M1C60_RS02715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1C60_RS02715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M1C60_RS02730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M1C60_RS02750	COG1228	amidohydrolase
M1C60_RS02755	COG1090	epimerase
M1C60_RS02785	COG1988	membrane-bound metal-dependent
M1C60_RS02790	COG1194	a g-specific adenine glycosylase
M1C60_RS02815	COG1132	(ABC) transporter
M1C60_RS02820	COG4129	membrane
M1C60_RS02825	COG0069	glutamate synthase activity
M1C60_RS02825	COG0070	glutamate synthase
M1C60_RS02825	COG0067	glutamate synthase
M1C60_RS02835	COG4555	ABC transporter
M1C60_RS02855	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1C60_RS02860	COG0735	belongs to the Fur family
M1C60_RS02975	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
M1C60_RS02980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1C60_RS02990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1C60_RS03000	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1C60_RS03010	COG2766	serine protein kinase
M1C60_RS03030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1C60_RS03040	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1C60_RS03045	COG2268	Band 7 protein
M1C60_RS03055	COG3290	protein histidine kinase activity
M1C60_RS03060	COG4565	transcriptional regulatory protein
M1C60_RS03065	COG2851	Citrate transporter
M1C60_RS03085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1C60_RS03090	COG3842	ATPase activity
M1C60_RS03095	COG1175	transmembrane transport
M1C60_RS03100	COG0395	ABC-type sugar transport system, permease component
M1C60_RS03110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1C60_RS03115	COG0745	RESPONSE REGULATOR receiver
M1C60_RS03120	COG5002	protein histidine kinase activity
M1C60_RS03130	COG4990	cell redox homeostasis
M1C60_RS03140	COG3290	protein histidine kinase activity
M1C60_RS03145	COG4565	transcriptional regulatory protein
M1C60_RS03150	COG3493	citrate carrier protein
M1C60_RS03155	COG0281	malic enzyme
M1C60_RS03170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS03180	COG5002	protein histidine kinase activity
M1C60_RS03185	COG0745	RESPONSE REGULATOR receiver
M1C60_RS03195	COG0456	acetyltransferase
M1C60_RS03195	COG0454	-acetyltransferase
M1C60_RS03200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1C60_RS03205	COG3383	formate dehydrogenase (NAD+) activity
M1C60_RS03225	COG0531	amino acid
M1C60_RS03230	COG0640	Transcriptional regulator
M1C60_RS03235	COG2217	Heavy metal translocating P-type atpase
M1C60_RS03240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M1C60_RS03255	COG3227	Zinc metalloprotease (Elastase)
M1C60_RS03275	COG2720	vancomycin resistance protein
M1C60_RS03280	COG1316	TRANSCRIPTIONal
M1C60_RS03285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS03290	COG0346	lactoylglutathione lyase activity
M1C60_RS03300	COG1027	Aspartate ammonia-lyase
M1C60_RS03305	COG1620	l-lactate permease
M1C60_RS03320	COG3104	oligopeptide transport
M1C60_RS03325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS03330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS03335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS03345	COG2226	methyltransferase
M1C60_RS03350	COG0156	8-amino-7-oxononanoate synthase activity
M1C60_RS03370	COG0714	Associated with various cellular activities
M1C60_RS03375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_RS03395	COG0531	amino acid
M1C60_RS03400	COG2188	Transcriptional regulator
M1C60_RS03405	COG1263	PTS System
M1C60_RS03405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_RS03410	COG0366	Alpha amylase catalytic
M1C60_RS03425	COG0697	spore germination
M1C60_RS03435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1C60_RS03440	COG1115	amino acid carrier protein
M1C60_RS03445	COG1126	abc transporter atp-binding protein
M1C60_RS03450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_RS03455	COG0765	amino acid transport
M1C60_RS03460	COG0765	amino acid transport
M1C60_RS03465	COG0833	amino acid
M1C60_RS03490	COG2378	regulation of single-species biofilm formation
M1C60_RS03495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1C60_RS03500	COG5002	protein histidine kinase activity
M1C60_RS03515	COG0659	secondary active sulfate transmembrane transporter activity
M1C60_RS03530	COG0747	negative chemotaxis
M1C60_RS03540	COG0601	transmembrane transport
M1C60_RS03545	COG4608	Belongs to the ABC transporter superfamily
M1C60_RS03555	COG2271	Major facilitator Superfamily
M1C60_RS03560	COG1846	Transcriptional regulator
M1C60_RS03570	COG1609	Transcriptional regulator
M1C60_RS03575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1C60_RS03590	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1C60_RS03595	COG1879	ABC-type sugar transport system periplasmic component
M1C60_RS03620	COG1063	alcohol dehydrogenase
M1C60_RS03635	COG3568	Endonuclease Exonuclease Phosphatase
M1C60_RS03660	COG1968	undecaprenyl-diphosphatase activity
M1C60_RS03665	COG0840	transmembrane signaling receptor activity
M1C60_RS03675	COG1476	TRANSCRIPTIONal
M1C60_RS03690	COG3104	oligopeptide transport
M1C60_RS03695	COG1114	Component of the transport system for branched-chain amino acids
M1C60_RS03710	COG1113	amino acid transport
M1C60_RS03715	COG2252	PERMEase
M1C60_RS03740	COG0569	domain protein
M1C60_RS03740	COG0475	glutathione-regulated potassium exporter activity
M1C60_RS03755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1C60_RS03760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1C60_RS03765	COG4990	cell redox homeostasis
M1C60_RS03780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_RS03785	COG0697	spore germination
M1C60_RS03790	COG0531	amino acid
M1C60_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1C60_RS03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1C60_RS03810	COG1918	ferrous iron import across plasma membrane
M1C60_RS03810	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M1C60_RS03815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1C60_RS03820	COG0573	inorganic phosphate transmembrane transporter activity
M1C60_RS03825	COG0581	inorganic phosphate transmembrane transporter activity
M1C60_RS03955	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M1C60_RS03975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1C60_RS03980	COG1116	anion transmembrane transporter activity
M1C60_RS03985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_RS03990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1C60_RS03995	COG0352	thiamine-phosphate diphosphorylase activity
M1C60_RS04000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_RS04005	COG2104	thiamine diphosphate biosynthetic process
M1C60_RS04015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_RS04020	COG0351	phosphomethylpyrimidine kinase
M1C60_RS04060	COG2205	protein histidine kinase activity
M1C60_RS04065	COG2814	Major facilitator Superfamily
M1C60_RS04070	COG1846	Transcriptional regulator
M1C60_RS04085	COG2252	PERMEase
M1C60_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS04105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1C60_RS04110	COG1621	beta-fructofuranosidase activity
M1C60_RS04115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_RS04115	COG1263	PTS System
M1C60_RS04120	COG1609	Transcriptional regulator
M1C60_RS04130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_RS04135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M1C60_RS04170	COG0778	Nitroreductase
M1C60_RS04175	COG2719	SpoVR family
M1C60_RS04200	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1C60_RS04205	COG1937	Protein conserved in bacteria
M1C60_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
M1C60_RS04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_RS04215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_RS04220	COG0425	Belongs to the sulfur carrier protein TusA family
M1C60_RS04235	COG2210	Belongs to the sulfur carrier protein TusA family
M1C60_RS04240	COG0730	response to heat
M1C60_RS04250	COG1316	TRANSCRIPTIONal
M1C60_RS04255	COG0604	alcohol dehydrogenase
M1C60_RS04260	COG1283	sodium-dependent phosphate transmembrane transporter activity
M1C60_RS04275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1C60_RS04275	COG3711	transcriptional antiterminator
M1C60_RS04280	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1C60_RS04285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1C60_RS04305	COG1388	LysM domain
M1C60_RS04305	COG3584	3D domain protein
M1C60_RS04310	COG0577	efflux transmembrane transporter activity
M1C60_RS04315	COG1136	(ABC) transporter
M1C60_RS04325	COG5522	Integral membrane protein (intg_mem_TP0381)
M1C60_RS04340	COG1114	Component of the transport system for branched-chain amino acids
M1C60_RS04345	COG3546	catalase activity
M1C60_RS04380	COG0586	Pfam SNARE associated Golgi protein
M1C60_RS04415	COG0531	amino acid
M1C60_RS04420	COG0475	glutathione-regulated potassium exporter activity
M1C60_RS04430	COG1737	Transcriptional regulator
M1C60_RS04440	COG1263	PTS System
M1C60_RS04440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_RS04450	COG2259	Doxx family
M1C60_RS04465	COG0697	spore germination
M1C60_RS04470	COG1522	sequence-specific DNA binding
M1C60_RS04485	COG2076	Multidrug Resistance protein
M1C60_RS04490	COG1309	transcriptional regulator
M1C60_RS04495	COG2814	Major facilitator Superfamily
M1C60_RS04500	COG1733	regulation of RNA biosynthetic process
M1C60_RS04510	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1C60_RS04515	COG4533	DNA binding
M1C60_RS04520	COG2211	Major facilitator Superfamily
M1C60_RS04530	COG0693	protein deglycase activity
M1C60_RS04535	COG0693	protein deglycase activity
M1C60_RS04535	COG0753	catalase activity
M1C60_RS04545	COG0531	amino acid
M1C60_RS04550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1C60_RS04560	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS04565	COG1132	(ABC) transporter
M1C60_RS04575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_RS04580	COG0765	amino acid transport
M1C60_RS04585	COG1126	abc transporter atp-binding protein
M1C60_RS04600	COG0189	ligase activity
M1C60_RS04630	COG0028	Belongs to the TPP enzyme family
M1C60_RS04635	COG3527	Alpha-acetolactate decarboxylase
M1C60_RS04650	COG0561	phosphatase activity
M1C60_RS04665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1C60_RS04680	COG0659	secondary active sulfate transmembrane transporter activity
M1C60_RS04700	COG0653	protein targeting
M1C60_RS04705	COG2244	polysaccharide biosynthetic process
M1C60_RS04715	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS04720	COG4196	transglutaminase domain protein
M1C60_RS04735	COG1696	Membrane protein involved in D-alanine export
M1C60_RS04750	COG1024	Enoyl-CoA hydratase
M1C60_RS04770	COG1363	Peptidase, m42
M1C60_RS04790	COG3938	Belongs to the proline racemase family
M1C60_RS04830	COG0601	transmembrane transport
M1C60_RS04835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_RS04845	COG4608	Belongs to the ABC transporter superfamily
M1C60_RS04880	COG0477	Major facilitator Superfamily
M1C60_RS04885	COG3290	protein histidine kinase activity
M1C60_RS04890	COG4565	transcriptional regulatory protein
M1C60_RS04895	COG3181	Tripartite tricarboxylate transporter family receptor
M1C60_RS04925	COG0789	Transcriptional regulator
M1C60_RS04925	COG4978	Transcriptional regulator
M1C60_RS04940	COG0305	Participates in initiation and elongation during chromosome replication
M1C60_RS04980	COG0477	Major facilitator Superfamily
M1C60_RS05025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1C60_RS05025	COG3320	Male sterility
M1C60_RS05030	COG1309	transcriptional regulator
M1C60_RS05050	COG1183	phosphatidylcholine synthase activity
M1C60_RS05070	COG2376	Dihydroxyacetone kinase
M1C60_RS05080	COG2376	Dihydroxyacetone kinase
M1C60_RS05085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1C60_RS05090	COG1959	2 iron, 2 sulfur cluster binding
M1C60_RS05120	COG3437	response regulator, receiver
M1C60_RS05120	COG2770	Histidine kinase
M1C60_RS05170	COG3237	CsbD-like
M1C60_RS05195	COG1191	sigma factor activity
M1C60_RS05205	COG2208	phosphoserine phosphatase activity
M1C60_RS05210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1C60_RS05215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_RS05215	COG2205	protein histidine kinase activity
M1C60_RS05215	COG2198	Histidine kinase
M1C60_RS05215	COG0784	Response regulator, receiver
M1C60_RS05270	COG0420	3'-5' exonuclease activity
M1C60_RS05295	COG1309	transcriptional regulator
M1C60_RS05300	COG2814	Major facilitator Superfamily
M1C60_RS05305	COG0346	lactoylglutathione lyase activity
M1C60_RS05315	COG0457	Tetratricopeptide repeat
M1C60_RS05325	COG2267	carboxylic ester hydrolase activity
M1C60_RS05345	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M1C60_RS05350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M1C60_RS05360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M1C60_RS05400	COG0477	Major facilitator Superfamily
M1C60_RS05405	COG0477	Major facilitator Superfamily
M1C60_RS05415	COG3973	AAA domain
M1C60_RS05420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1C60_RS05440	COG4980	gas vesicle protein
M1C60_RS05445	COG0537	adenosine 5'-monophosphoramidase activity
M1C60_RS05450	COG1131	(ABC) transporter
M1C60_RS05455	COG4473	ABC transporter
M1C60_RS05470	COG1309	transcriptional regulator
M1C60_RS05480	COG3402	PFAM membrane-flanked domain
M1C60_RS05525	COG3402	PFAM membrane-flanked domain
M1C60_RS05530	COG3428	Bacterial PH domain
M1C60_RS05535	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_RS05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_RS05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
M1C60_RS05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1C60_RS05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1C60_RS05590	COG1309	transcriptional regulator
M1C60_RS05595	COG1511	domain protein
M1C60_RS05620	COG1609	Transcriptional regulator
M1C60_RS05630	COG1234	tRNA 3'-trailer cleavage
M1C60_RS05635	COG0095	Lipoate-protein ligase
M1C60_RS05645	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_RS05675	COG3209	COG3209 Rhs family protein
M1C60_RS05715	COG1078	dGTPase activity
M1C60_RS05725	COG1595	DNA-templated transcription, initiation
M1C60_RS05730	COG2207	Transcriptional regulator
M1C60_RS05730	COG3708	Transcriptional regulator
M1C60_RS05745	COG2205	protein histidine kinase activity
M1C60_RS05750	COG0745	RESPONSE REGULATOR receiver
M1C60_RS05775	COG0501	Belongs to the peptidase M48B family
M1C60_RS05780	COG0840	transmembrane signaling receptor activity
M1C60_RS05785	COG0697	spore germination
M1C60_RS05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1C60_RS05810	COG2224	Isocitrate lyase
M1C60_RS05835	COG4903	ComK protein
M1C60_RS05840	COG0398	Pfam SNARE associated Golgi protein
M1C60_RS05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
M1C60_RS05855	COG1074	ATP-dependent DNA helicase activity
M1C60_RS05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1C60_RS05925	COG0367	asparagine synthase
M1C60_RS05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M1C60_RS05935	COG0753	catalase activity
M1C60_RS05940	COG0004	ammonium transporteR
M1C60_RS05960	COG2996	Protein conserved in bacteria
M1C60_RS05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1C60_RS05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS05995	COG0561	phosphatase activity
M1C60_RS06005	COG0542	response to heat
M1C60_RS06015	COG2267	carboxylic ester hydrolase activity
M1C60_RS06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_RS06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1C60_RS06040	COG5504	Zn-dependent protease
M1C60_RS06050	COG0180	Tryptophanyl-tRNA synthetase
M1C60_RS06060	COG4166	transmembrane transport
M1C60_RS06065	COG0601	transmembrane transport
M1C60_RS06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_RS06075	COG0444	Belongs to the ABC transporter superfamily
M1C60_RS06080	COG4608	Belongs to the ABC transporter superfamily
M1C60_RS06085	COG0534	Mate efflux family protein
M1C60_RS06090	COG4166	transmembrane transport
M1C60_RS06105	COG0861	Integral membrane protein TerC family
M1C60_RS06110	COG4862	establishment of competence for transformation
M1C60_RS06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_RS06125	COG1164	Oligoendopeptidase f
M1C60_RS06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1C60_RS06140	COG2346	COG2346, Truncated hemoglobins
M1C60_RS06145	COG4116	CYTH
M1C60_RS06155	COG2357	RelA SpoT domain protein
M1C60_RS06165	COG0564	pseudouridine synthase activity
M1C60_RS06185	COG1216	Glycosyl transferase, family 2
M1C60_RS06185	COG0463	Glycosyl transferase, family 2
M1C60_RS06205	COG0457	Tetratricopeptide repeat
M1C60_RS06205	COG0463	Glycosyl transferase, family 2
M1C60_RS06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M1C60_RS06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
M1C60_RS06285	COG2153	protein acetylation
M1C60_RS06295	COG2382	esterase
M1C60_RS06310	COG5492	domain, Protein
M1C60_RS06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_RS06325	COG0512	Glutamine amidotransferase of anthranilate synthase
M1C60_RS06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1C60_RS06360	COG1620	l-lactate permease
M1C60_RS06365	COG5634	Uncharacterized conserved protein (DUF2278)
M1C60_RS06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_RS06430	COG1476	TRANSCRIPTIONal
M1C60_RS06490	COG2226	methyltransferase
M1C60_RS06500	COG1686	Belongs to the peptidase S11 family
M1C60_RS06505	COG0681	Belongs to the peptidase S26 family
M1C60_RS06540	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS06545	COG3842	ATPase activity
M1C60_RS06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
M1C60_RS06555	COG1177	transmembrane transport
M1C60_RS06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
M1C60_RS06570	COG2409	Drug exporters of the RND superfamily
M1C60_RS06580	COG0564	pseudouridine synthase activity
M1C60_RS06590	COG2340	Cysteine-rich secretory protein family
M1C60_RS06595	COG0247	lactate metabolic process
M1C60_RS06600	COG0277	FAD linked oxidase domain protein
M1C60_RS06605	COG3835	regulator
M1C60_RS06615	COG0745	RESPONSE REGULATOR receiver
M1C60_RS06620	COG5002	protein histidine kinase activity
M1C60_RS06625	COG2186	Transcriptional regulator
M1C60_RS06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1C60_RS06655	COG2116	formate transmembrane transporter activity
M1C60_RS06660	COG0861	Integral membrane protein TerC family
M1C60_RS06665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1C60_RS06675	COG2030	dehydratase
M1C60_RS06695	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS06700	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1C60_RS06705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_RS06710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1C60_RS06725	COG1840	ABC-type Fe3 transport system, periplasmic component
M1C60_RS06755	COG1349	DNA-binding transcription factor activity
M1C60_RS06775	COG2861	carbohydrate metabolic process
M1C60_RS06785	COG3852	Histidine kinase
M1C60_RS06790	COG1846	Transcriptional regulator
M1C60_RS06800	COG2318	DinB family
M1C60_RS06810	COG5002	protein histidine kinase activity
M1C60_RS06820	COG0720	synthase
M1C60_RS06835	COG4873	Protein conserved in bacteria
M1C60_RS06865	COG1780	Probably involved in ribonucleotide reductase function
M1C60_RS06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1C60_RS06890	COG1725	Transcriptional regulator
M1C60_RS06895	COG1131	(ABC) transporter
M1C60_RS06905	COG1131	(ABC) transporter
M1C60_RS06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1C60_RS06925	COG1522	sequence-specific DNA binding
M1C60_RS06935	COG1335	isochorismatase
M1C60_RS06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1C60_RS06950	COG2070	2-Nitropropane dioxygenase
M1C60_RS06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1C60_RS06965	COG1696	Membrane protein involved in D-alanine export
M1C60_RS06990	COG0716	FMN binding
M1C60_RS07005	COG3173	Aminoglycoside phosphotransferase
M1C60_RS07025	COG0534	Mate efflux family protein
M1C60_RS07030	COG1968	undecaprenyl-diphosphatase activity
M1C60_RS07045	COG1846	Transcriptional regulator
M1C60_RS07055	COG1301	dicarboxylic acid transport
M1C60_RS07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1C60_RS07065	COG4709	membrane
M1C60_RS07070	COG3874	Sporulation protein YtfJ
M1C60_RS07090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_RS07095	COG0028	Belongs to the TPP enzyme family
M1C60_RS07100	COG0440	acetolactate synthase activity
M1C60_RS07105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M1C60_RS07115	COG0473	3-isopropylmalate dehydrogenase activity
M1C60_RS07140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1C60_RS07175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1C60_RS07190	COG1183	phosphatidylcholine synthase activity
M1C60_RS07195	COG1368	sulfuric ester hydrolase activity
M1C60_RS07205	COG0019	diaminopimelate decarboxylase activity
M1C60_RS07225	COG0529	Catalyzes the synthesis of activated sulfate
M1C60_RS07230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1C60_RS07250	COG1648	precorrin-2 dehydrogenase activity
M1C60_RS07255	COG0733	neurotransmitter:sodium symporter activity
M1C60_RS07275	COG1757	Na H antiporter
M1C60_RS07290	COG4758	membrane
M1C60_RS07295	COG4585	Histidine kinase
M1C60_RS07300	COG2197	response regulator
M1C60_RS07310	COG1114	Component of the transport system for branched-chain amino acids
M1C60_RS07345	COG1017	nitric oxide dioxygenase activity
M1C60_RS07345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1C60_RS07360	COG0730	response to heat
M1C60_RS07365	COG0306	phosphate transporter
M1C60_RS07370	COG1392	Phosphate transport regulator
M1C60_RS07375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_RS07390	COG3852	Histidine kinase
M1C60_RS07395	COG1801	Protein of unknown function DUF72
M1C60_RS07405	COG0582	viral genome integration into host DNA
M1C60_RS07410	COG5002	protein histidine kinase activity
M1C60_RS07430	COG0392	lysyltransferase activity
M1C60_RS07430	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M1C60_RS07445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1C60_RS07450	COG1686	Belongs to the peptidase S11 family
M1C60_RS07455	COG2715	membrane protein required for spore maturation
M1C60_RS07460	COG0700	Nucleoside recognition
M1C60_RS07465	COG1187	pseudouridine synthase activity
M1C60_RS07475	COG1333	cytochrome c biogenesis protein
M1C60_RS07480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1C60_RS07485	COG0745	RESPONSE REGULATOR receiver
M1C60_RS07490	COG5002	protein histidine kinase activity
M1C60_RS07495	COG2096	Adenosyltransferase
M1C60_RS07510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M1C60_RS07515	COG1141	Ferredoxin
M1C60_RS07520	COG4955	Helix-turn-helix domain
M1C60_RS07525	COG0514	ATP-dependent DNA helicase (RecQ)
M1C60_RS07530	COG1266	CAAX protease self-immunity
M1C60_RS07550	COG4862	establishment of competence for transformation
M1C60_RS07555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1C60_RS07575	COG0492	ferredoxin-NADP+ reductase activity
M1C60_RS07650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1C60_RS07665	COG0142	geranyltranstransferase activity
M1C60_RS07675	COG0142	geranyltranstransferase activity
M1C60_RS07695	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M1C60_RS07700	COG0457	Tetratricopeptide repeat
M1C60_RS07720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M1C60_RS07730	COG4347	Protein of unknown function (DUF1405)
M1C60_RS07745	COG2738	Putative neutral zinc metallopeptidase
M1C60_RS07755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS07760	COG1694	Mazg nucleotide pyrophosphohydrolase
M1C60_RS07775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1C60_RS07780	COG0438	transferase activity, transferring glycosyl groups
M1C60_RS07815	COG1199	ATP-dependent helicase activity
M1C60_RS07815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1C60_RS07835	COG3935	DnaD domain protein
M1C60_RS07840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1C60_RS07850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_RS07850	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1C60_RS07910	COG0116	Belongs to the methyltransferase superfamily
M1C60_RS07920	COG1199	ATP-dependent helicase activity
M1C60_RS07925	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M1C60_RS07935	COG3173	Aminoglycoside phosphotransferase
M1C60_RS07940	COG0024	Methionine aminopeptidase
M1C60_RS07950	COG2233	PERMEase
M1C60_RS07955	COG2311	Membrane
M1C60_RS07960	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1C60_RS07970	COG0456	acetyltransferase
M1C60_RS08020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1C60_RS08045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1C60_RS08060	COG1215	transferase activity, transferring glycosyl groups
M1C60_RS08065	COG0438	transferase activity, transferring glycosyl groups
M1C60_RS08080	COG0454	-acetyltransferase
M1C60_RS08100	COG0328	RNA-DNA hybrid ribonuclease activity
M1C60_RS08140	COG1280	lysine exporter protein (LysE YggA)
M1C60_RS08155	COG3162	membrane
M1C60_RS08160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_RS08165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1C60_RS08175	COG0475	glutathione-regulated potassium exporter activity
M1C60_RS08180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1C60_RS08185	COG0789	Transcriptional regulator
M1C60_RS08185	COG4978	Transcriptional regulator
M1C60_RS08195	COG2323	membrane
M1C60_RS08200	COG1434	Gram-negative-bacterium-type cell wall biogenesis
M1C60_RS08255	COG1923	regulation of RNA biosynthetic process
M1C60_RS08265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1C60_RS08270	COG1360	Flagellar Motor Protein
M1C60_RS08275	COG2201	protein-glutamate methylesterase activity
M1C60_RS08285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1C60_RS08285	COG1776	CheC inhibitor of MCP methylation
M1C60_RS08300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M1C60_RS08320	COG1256	bacterial-type flagellum assembly
M1C60_RS08345	COG1815	bacterial-type flagellum-dependent cell motility
M1C60_RS08350	COG1558	bacterial-type flagellum-dependent cell motility
M1C60_RS08365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1C60_RS08375	COG1157	protein secretion by the type III secretion system
M1C60_RS08410	COG0784	Response regulator, receiver
M1C60_RS08410	COG0835	chemotaxis
M1C60_RS08420	COG0463	Glycosyl transferase, family 2
M1C60_RS08445	COG0457	Tetratricopeptide repeat
M1C60_RS08445	COG0463	Glycosyl transferase, family 2
M1C60_RS08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M1C60_RS08465	COG0741	lytic transglycosylase activity
M1C60_RS08480	COG1776	CheC inhibitor of MCP methylation
M1C60_RS08480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M1C60_RS08490	COG1338	Plays a role in the flagellum-specific transport system
M1C60_RS08495	COG1987	bacterial-type flagellum assembly
M1C60_RS08505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1C60_RS08510	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M1C60_RS08515	COG1419	protein localization to endoplasmic reticulum
M1C60_RS08520	COG4786	Flagellar basal body rod
M1C60_RS08525	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1C60_RS08550	COG1309	transcriptional regulator
M1C60_RS08570	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_RS08595	COG0583	DNA-binding transcription factor activity
M1C60_RS08605	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1C60_RS08615	COG1234	tRNA 3'-trailer cleavage
M1C60_RS08640	COG1686	Belongs to the peptidase S11 family
M1C60_RS08650	COG0406	alpha-ribazole phosphatase activity
M1C60_RS08680	COG0367	asparagine synthase
M1C60_RS08710	COG1802	Transcriptional regulator
M1C60_RS08715	COG0697	spore germination
M1C60_RS08720	COG0523	cobalamin synthesis protein
M1C60_RS08725	COG0701	Predicted permease
M1C60_RS08735	COG0438	transferase activity, transferring glycosyl groups
M1C60_RS08735	COG1216	Glycosyl transferase, family 2
M1C60_RS08740	COG1757	Na H antiporter
M1C60_RS08745	COG0114	fumarate hydratase activity
M1C60_RS08770	COG3340	Belongs to the peptidase S51 family
M1C60_RS08790	COG0785	Cytochrome C biogenesis protein
M1C60_RS08820	COG2733	membrane
M1C60_RS08855	COG1131	(ABC) transporter
M1C60_RS08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_RS08875	COG0528	UMP kinase activity
M1C60_RS08885	COG1027	Aspartate ammonia-lyase
M1C60_RS08890	COG0281	malic enzyme
M1C60_RS08895	COG4191	Histidine kinase
M1C60_RS08900	COG0784	Response regulator, receiver
M1C60_RS08905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1C60_RS08965	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS08975	COG2814	Major facilitator Superfamily
M1C60_RS08990	COG1966	Carbon starvation protein
M1C60_RS09005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_RS09015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1C60_RS09025	COG2223	nitrite transmembrane transporter activity
M1C60_RS09030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1C60_RS09045	COG2244	polysaccharide biosynthetic process
M1C60_RS09050	COG0733	neurotransmitter:sodium symporter activity
M1C60_RS09060	COG5566	PFAM Mor transcription activator
M1C60_RS09065	COG2323	membrane
M1C60_RS09080	COG2084	Dehydrogenase
M1C60_RS09095	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1C60_RS09105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_RS09110	COG0028	Belongs to the TPP enzyme family
M1C60_RS09115	COG0440	acetolactate synthase activity
M1C60_RS09120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M1C60_RS09130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1C60_RS09155	COG2814	Major facilitator Superfamily
M1C60_RS09160	COG3384	dioxygenase
M1C60_RS09170	COG3279	Response regulator of the LytR AlgR family
M1C60_RS09175	COG0427	acetyl-CoA hydrolase
M1C60_RS09195	COG1073	alpha beta
M1C60_RS09225	COG0535	radical SAM domain protein
M1C60_RS09230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS09250	COG1914	H( )-stimulated, divalent metal cation uptake system
M1C60_RS09265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1C60_RS09300	COG2390	Transcriptional regulator
M1C60_RS09310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS09315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M1C60_RS09330	COG4224	UPF0291 protein
M1C60_RS09350	COG0006	proline dipeptidase activity
M1C60_RS09355	COG2132	Multicopper oxidase
M1C60_RS09370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1C60_RS09385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1C60_RS09400	COG1276	copper resistance
M1C60_RS09400	COG2372	response to copper ion
M1C60_RS09405	COG4549	nuclear export factor GLE1
M1C60_RS09415	COG0697	spore germination
M1C60_RS09420	COG0583	DNA-binding transcription factor activity
M1C60_RS09425	COG1959	2 iron, 2 sulfur cluster binding
M1C60_RS09430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1C60_RS09450	COG0628	permease
M1C60_RS09460	COG1231	oxidoreductase activity
M1C60_RS09465	COG0523	cobalamin synthesis protein
M1C60_RS09480	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_RS09485	COG2030	dehydratase
M1C60_RS09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_RS09500	COG0411	ABC transporter
M1C60_RS09520	COG0583	DNA-binding transcription factor activity
M1C60_RS09530	COG1942	4-Oxalocrotonate Tautomerase
M1C60_RS09540	COG1846	Transcriptional regulator
M1C60_RS09550	COG1271	oxidase subunit
M1C60_RS09555	COG1294	oxidase, subunit
M1C60_RS09560	COG4988	ABC transporter
M1C60_RS09565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M1C60_RS09585	COG1686	Belongs to the peptidase S11 family
M1C60_RS09600	COG0791	NLP P60 protein
M1C60_RS09600	COG1388	LysM domain
M1C60_RS09615	COG0745	RESPONSE REGULATOR receiver
M1C60_RS09620	COG5002	protein histidine kinase activity
M1C60_RS09630	COG0300	oxidoreductase activity
M1C60_RS09665	COG0460	homoserine dehydrogenase
M1C60_RS09690	COG1316	TRANSCRIPTIONal
M1C60_RS09700	COG0745	RESPONSE REGULATOR receiver
M1C60_RS09705	COG5002	protein histidine kinase activity
M1C60_RS09720	COG1285	pathogenesis
M1C60_RS09725	COG1247	-acetyltransferase
M1C60_RS09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1C60_RS09755	COG1082	Xylose isomerase domain protein TIM barrel
M1C60_RS09770	COG1279	arginine transmembrane transporter activity
M1C60_RS09780	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1C60_RS09820	COG2002	toxin-antitoxin pair type II binding
M1C60_RS09825	COG1404	Belongs to the peptidase S8 family
M1C60_RS09830	COG0640	Transcriptional regulator
M1C60_RS09835	COG0667	Aldo Keto reductase
M1C60_RS09840	COG2814	Major facilitator Superfamily
M1C60_RS09865	COG0840	transmembrane signaling receptor activity
M1C60_RS09880	COG3949	Membrane
M1C60_RS09885	COG0783	Belongs to the Dps family
M1C60_RS09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1C60_RS09910	COG1231	oxidoreductase activity
M1C60_RS09920	COG4989	oxidoreductase activity
M1C60_RS09925	COG0523	cobalamin synthesis protein
M1C60_RS09930	COG0456	acetyltransferase
M1C60_RS09990	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1C60_RS09990	COG3443	Belongs to the bacterial solute-binding protein 9 family
M1C60_RS10000	COG0702	epimerase
M1C60_RS10010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1C60_RS10020	COG4166	transmembrane transport
M1C60_RS10035	COG0406	alpha-ribazole phosphatase activity
M1C60_RS10045	COG5337	Spore coat protein CotH
M1C60_RS10050	COG1051	belongs to the nudix hydrolase family
M1C60_RS10055	COG0586	Pfam SNARE associated Golgi protein
M1C60_RS10060	COG2244	polysaccharide biosynthetic process
M1C60_RS10070	COG0701	Predicted permease
M1C60_RS10075	COG3689	TIGRFAM TIGR03943 family protein
M1C60_RS10080	COG1607	acyl-coa hydrolase
M1C60_RS10090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_RS10105	COG0702	epimerase
M1C60_RS10110	COG2839	Protein conserved in bacteria
M1C60_RS10115	COG1253	flavin adenine dinucleotide binding
M1C60_RS10130	COG1114	Component of the transport system for branched-chain amino acids
M1C60_RS10135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_RS10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS10165	COG1876	peptidase activity
M1C60_RS10175	COG0154	amidase activity
M1C60_RS10180	COG2211	Major facilitator Superfamily
M1C60_RS10200	COG0561	phosphatase activity
M1C60_RS10210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1C60_RS10215	COG4106	trans-aconitate 2-methyltransferase activity
M1C60_RS10230	COG1819	glycosyl
M1C60_RS10235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS10240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS10275	COG0456	acetyltransferase
M1C60_RS10330	COG3874	Sporulation protein YtfJ
M1C60_RS10355	COG2226	methyltransferase
M1C60_RS10380	COG0346	lactoylglutathione lyase activity
M1C60_RS10390	COG0604	alcohol dehydrogenase
M1C60_RS10395	COG1595	DNA-templated transcription, initiation
M1C60_RS10420	COG0386	Belongs to the glutathione peroxidase family
M1C60_RS10425	COG1305	Transglutaminase-like
M1C60_RS10430	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M1C60_RS10435	COG0714	Associated with various cellular activities
M1C60_RS10450	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M1C60_RS10455	COG1140	nitrate reductase beta subunit
M1C60_RS10460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M1C60_RS10465	COG2181	nitrate reductase activity
M1C60_RS10485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1C60_RS10490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1C60_RS10495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_RS10500	COG0303	'Molybdopterin
M1C60_RS10505	COG0314	molybdopterin synthase activity
M1C60_RS10515	COG2223	nitrite transmembrane transporter activity
M1C60_RS10530	COG1648	precorrin-2 dehydrogenase activity
M1C60_RS10540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1C60_RS10540	COG1587	Uroporphyrinogen-III synthase
M1C60_RS10545	COG2146	nitrite reductase [NAD(P)H] activity
M1C60_RS10550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1C60_RS10555	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
M1C60_RS10590	COG2359	stage V sporulation protein S
M1C60_RS10615	COG1418	mRNA catabolic process
M1C60_RS10620	COG0488	(ABC) transporter
M1C60_RS10635	COG0629	single-stranded DNA binding
M1C60_RS10650	COG1413	lyase activity
M1C60_RS10665	COG2521	methyltransferase
M1C60_RS10665	COG2136	Putative SAM-dependent methyltransferase
M1C60_RS10670	COG0018	arginyl-trna synthetase
M1C60_RS10695	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1C60_RS10715	COG0017	Asparaginyl-tRNA synthetase
M1C60_RS10735	COG1674	ftsk spoiiie
M1C60_RS10805	COG1929	Belongs to the glycerate kinase type-1 family
M1C60_RS10810	COG0471	metal ion transport
M1C60_RS10815	COG0745	RESPONSE REGULATOR receiver
M1C60_RS10820	COG3850	Histidine kinase
M1C60_RS10820	COG5002	protein histidine kinase activity
M1C60_RS10835	COG0733	neurotransmitter:sodium symporter activity
M1C60_RS10860	COG2610	gluconate transmembrane transporter activity
M1C60_RS10865	COG1454	alcohol dehydrogenase
M1C60_RS10870	COG1794	racemase activity, acting on amino acids and derivatives
M1C60_RS10880	COG0456	acetyltransferase
M1C60_RS10895	COG1131	(ABC) transporter
M1C60_RS10910	COG0546	phosphoglycolate phosphatase activity
M1C60_RS10930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_RS10945	COG0768	penicillin binding
M1C60_RS10950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1C60_RS10955	COG0204	Acyl-transferase
M1C60_RS10960	COG1272	protein, Hemolysin III
M1C60_RS10970	COG0805	protein transport
M1C60_RS10980	COG1307	EDD domain protein, DegV family
M1C60_RS10985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M1C60_RS10990	COG1999	signal sequence binding
M1C60_RS10995	COG0071	Belongs to the small heat shock protein (HSP20) family
M1C60_RS11000	COG0367	asparagine synthase
M1C60_RS11015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS11020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1C60_RS11055	COG0668	transmembrane transport
M1C60_RS11060	COG4585	Histidine kinase
M1C60_RS11060	COG2203	Gaf domain
M1C60_RS11065	COG2197	response regulator
M1C60_RS11075	COG1064	alcohol dehydrogenase
M1C60_RS11130	COG1125	glycine betaine transport
M1C60_RS11130	COG0517	IMP dehydrogenase activity
M1C60_RS11135	COG1174	glycine betaine transport
M1C60_RS11170	COG1253	flavin adenine dinucleotide binding
M1C60_RS11175	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS11180	COG5506	Protein of unknown function (DUF1694)
M1C60_RS11195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1C60_RS11200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1C60_RS11205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1C60_RS11210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M1C60_RS11215	COG0456	acetyltransferase
M1C60_RS11220	COG3829	transcription factor binding
M1C60_RS11225	COG1509	lysine 2,3-aminomutase activity
M1C60_RS11265	COG4326	sporulation control protein
M1C60_RS11270	COG0671	phosphoesterase, PA-phosphatase related
M1C60_RS11275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1C60_RS11280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_RS11310	COG1715	Restriction endonuclease
M1C60_RS11310	COG1787	Restriction endonuclease
M1C60_RS11400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1C60_RS11440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_RS11440	COG4499	WXG100 protein secretion system (Wss), protein YukC
M1C60_RS11450	COG2814	Major facilitator Superfamily
M1C60_RS11455	COG4841	protein insertion into membrane
M1C60_RS11460	COG0372	Belongs to the citrate synthase family
M1C60_RS11465	COG2079	MmgE PrpD family protein
M1C60_RS11470	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M1C60_RS11475	COG1960	acyl-CoA dehydrogenase activity
M1C60_RS11480	COG2084	Dehydrogenase
M1C60_RS11490	COG1280	lysine exporter protein (LysE YggA)
M1C60_RS11495	COG1024	Enoyl-CoA hydratase
M1C60_RS11510	COG0420	3'-5' exonuclease activity
M1C60_RS11515	COG0419	ATPase involved in DNA repair
M1C60_RS11535	COG2223	nitrite transmembrane transporter activity
M1C60_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS11545	COG1169	isochorismate synthase
M1C60_RS11550	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1C60_RS11555	COG1535	isochorismatase
M1C60_RS11555	COG3433	isochorismatase activity
M1C60_RS11560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1C60_RS11565	COG3251	PFAM MbtH domain protein
M1C60_RS11570	COG2814	Major facilitator Superfamily
M1C60_RS11585	COG0776	regulation of translation
M1C60_RS11595	COG2318	DinB family
M1C60_RS11605	COG1115	amino acid carrier protein
M1C60_RS11620	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_RS11625	COG1187	pseudouridine synthase activity
M1C60_RS11630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1C60_RS11645	COG0596	Alpha beta hydrolase
M1C60_RS11650	COG2814	Major facilitator Superfamily
M1C60_RS11670	COG2226	methyltransferase
M1C60_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS11750	COG1247	-acetyltransferase
M1C60_RS11780	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M1C60_RS11790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS11800	COG1278	Cold shock
M1C60_RS11815	COG0010	Belongs to the arginase family
M1C60_RS11820	COG0561	phosphatase activity
M1C60_RS11865	COG0583	DNA-binding transcription factor activity
M1C60_RS11870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1C60_RS11885	COG0583	DNA-binding transcription factor activity
M1C60_RS11890	COG2258	MOSC domain
M1C60_RS11905	COG1132	(ABC) transporter
M1C60_RS11930	COG1396	sequence-specific DNA binding
M1C60_RS11955	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
M1C60_RS11960	COG1595	DNA-templated transcription, initiation
M1C60_RS11985	COG1649	PFAM Uncharacterised BCR, COG1649
M1C60_RS12010	COG2971	BadF BadG BcrA BcrD
M1C60_RS12015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1C60_RS12020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1C60_RS12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS12070	COG1309	transcriptional regulator
M1C60_RS12085	COG1136	(ABC) transporter
M1C60_RS12085	COG0577	efflux transmembrane transporter activity
M1C60_RS12090	COG3615	Tellurite resistance protein tehB
M1C60_RS12090	COG0500	methyltransferase
M1C60_RS12100	COG2226	methyltransferase
M1C60_RS12105	COG3961	Belongs to the TPP enzyme family
M1C60_RS12110	COG1846	Transcriptional regulator
M1C60_RS12155	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1C60_RS12170	COG1595	DNA-templated transcription, initiation
M1C60_RS12180	COG0768	penicillin binding
M1C60_RS12190	COG2367	Beta-lactamase
M1C60_RS12195	COG0671	phosphoesterase, PA-phosphatase related
M1C60_RS12200	COG1609	Transcriptional regulator
M1C60_RS12205	COG2814	Major facilitator Superfamily
M1C60_RS12210	COG0673	inositol 2-dehydrogenase activity
M1C60_RS12220	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS12235	COG0191	fructose-bisphosphate aldolase activity
M1C60_RS12240	COG3718	enzyme involved in inositol metabolism
M1C60_RS12265	COG0457	Tetratricopeptide repeat
M1C60_RS12270	COG1476	TRANSCRIPTIONal
M1C60_RS12285	COG1876	peptidase activity
M1C60_RS12305	COG1309	transcriptional regulator
M1C60_RS12310	COG0488	(ABC) transporter
M1C60_RS12325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS12340	COG1252	NADH dehydrogenase
M1C60_RS12345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_RS12360	COG1131	(ABC) transporter
M1C60_RS12370	COG1309	transcriptional regulator
M1C60_RS12385	COG1960	acyl-CoA dehydrogenase activity
M1C60_RS12390	COG0439	Biotin carboxylase
M1C60_RS12395	COG0511	ligase activity, forming carbon-carbon bonds
M1C60_RS12400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1C60_RS12405	COG1024	Enoyl-CoA hydratase
M1C60_RS12410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1C60_RS12415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1C60_RS12425	COG1247	-acetyltransferase
M1C60_RS12430	COG0572	uridine kinase
M1C60_RS12440	COG2318	DinB family
M1C60_RS12445	COG1686	Belongs to the peptidase S11 family
M1C60_RS12470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1C60_RS12510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1C60_RS12510	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1C60_RS12535	COG2814	Major facilitator Superfamily
M1C60_RS12555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1C60_RS12575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS12590	COG1063	alcohol dehydrogenase
M1C60_RS12620	COG3773	Cell wall hydrolase
M1C60_RS12630	COG0745	RESPONSE REGULATOR receiver
M1C60_RS12645	COG0488	(ABC) transporter
M1C60_RS12660	COG1136	(ABC) transporter
M1C60_RS12685	COG0460	homoserine dehydrogenase
M1C60_RS12690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS12700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1C60_RS12770	COG2124	cytochrome p450
M1C60_RS12805	COG0561	phosphatase activity
M1C60_RS12815	COG0768	penicillin binding
M1C60_RS12820	COG1819	glycosyl
M1C60_RS12825	COG1794	racemase activity, acting on amino acids and derivatives
M1C60_RS12835	COG1122	ATPase activity
M1C60_RS12850	COG2205	protein histidine kinase activity
M1C60_RS12860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_RS12865	COG0604	alcohol dehydrogenase
M1C60_RS12870	COG0768	penicillin binding
M1C60_RS12880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_RS12915	COG0693	protein deglycase activity
M1C60_RS12945	COG2814	Major facilitator Superfamily
M1C60_RS12960	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_RS12980	COG0697	spore germination
M1C60_RS13010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_RS13020	COG2223	nitrite transmembrane transporter activity
M1C60_RS13035	COG2816	NAD+ diphosphatase activity
M1C60_RS13040	COG0592	DNA-directed DNA polymerase activity
M1C60_RS13045	COG1051	belongs to the nudix hydrolase family
M1C60_RS13080	COG3878	Protein conserved in bacteria
M1C60_RS13130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1C60_RS13145	COG0322	excinuclease ABC activity
M1C60_RS13185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_RS13210	COG1011	Hydrolase
M1C60_RS13230	COG0076	glutamate decarboxylase activity
M1C60_RS13245	COG1523	belongs to the glycosyl hydrolase 13 family
M1C60_RS13250	COG3227	Zinc metalloprotease (Elastase)
M1C60_RS13280	COG0697	spore germination
M1C60_RS13285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS13315	COG4129	membrane
M1C60_RS13320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS13335	COG2959	enzyme of heme biosynthesis
M1C60_RS13355	COG3483	tryptophan 2,3-dioxygenase activity
M1C60_RS13360	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
M1C60_RS13365	COG3844	kynureninase activity
M1C60_RS13370	COG1309	transcriptional regulator
M1C60_RS13400	COG3284	Transcriptional regulator
M1C60_RS13420	COG1349	DNA-binding transcription factor activity
M1C60_RS13440	COG1959	2 iron, 2 sulfur cluster binding
M1C60_RS13455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1C60_RS13460	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_RS13465	COG0022	dehydrogenase e1 component
M1C60_RS13470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1C60_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS13485	COG0456	acetyltransferase
M1C60_RS13485	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_RS13520	COG4175	Glycine betaine
M1C60_RS13520	COG0517	IMP dehydrogenase activity
M1C60_RS13545	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M1C60_RS13550	COG2153	protein acetylation
M1C60_RS13555	COG3397	chitin binding
M1C60_RS13570	COG2205	protein histidine kinase activity
M1C60_RS13600	COG0658	competence protein
M1C60_RS13600	COG2333	competence protein COMEC
M1C60_RS13650	COG3973	AAA domain
M1C60_RS13665	COG2105	PFAM AIG2 family protein
M1C60_RS13670	COG0514	ATP-dependent DNA helicase (RecQ)
M1C60_RS13690	COG4637	Psort location Cytoplasmic, score
M1C60_RS13715	COG3397	chitin binding
M1C60_RS13730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1C60_RS13735	COG1115	amino acid carrier protein
M1C60_RS13740	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS13745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1C60_RS13755	COG3938	Belongs to the proline racemase family
M1C60_RS13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1C60_RS13800	COG0586	Pfam SNARE associated Golgi protein
M1C60_RS13815	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M1C60_RS13820	COG0519	Catalyzes the synthesis of GMP from XMP
M1C60_RS13825	COG4166	transmembrane transport
M1C60_RS13835	COG4948	Mandelate Racemase Muconate Lactonizing
M1C60_RS13880	COG2936	dipeptidyl-peptidase activity
M1C60_RS13885	COG5002	protein histidine kinase activity
M1C60_RS13935	COG1307	EDD domain protein, DegV family
M1C60_RS13955	COG2814	Major facilitator Superfamily
M1C60_RS13965	COG1664	Polymer-forming cytoskeletal
M1C60_RS13970	COG0789	Transcriptional regulator
M1C60_RS13975	COG4533	DNA binding
M1C60_RS13980	COG0477	Major facilitator Superfamily
M1C60_RS13980	COG2814	Major facilitator Superfamily
M1C60_RS14000	COG2261	transglycosylase associated protein
M1C60_RS14015	COG2226	methyltransferase
M1C60_RS14050	COG0436	Aminotransferase
M1C60_RS14055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M1C60_RS14060	COG5146	pantothenate kinase activity
M1C60_RS14080	COG1131	(ABC) transporter
M1C60_RS14125	COG0628	permease
M1C60_RS14140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1C60_RS14145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_RS14150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1C60_RS14155	COG1116	anion transmembrane transporter activity
M1C60_RS14175	COG2816	NAD+ diphosphatase activity
M1C60_RS14195	COG2746	aminoglycoside 3-N-acetyltransferase activity
M1C60_RS14220	COG0697	spore germination
M1C60_RS14225	COG2318	DinB family
M1C60_RS14245	COG4912	Dna alkylation repair
M1C60_RS14265	COG0861	Integral membrane protein TerC family
M1C60_RS14270	COG1368	sulfuric ester hydrolase activity
M1C60_RS14275	COG0488	(ABC) transporter
M1C60_RS14290	COG1309	transcriptional regulator
M1C60_RS14305	COG0287	Prephenate dehydrogenase
M1C60_RS14310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M1C60_RS14315	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M1C60_RS14320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M1C60_RS14320	COG1605	Chorismate mutase
M1C60_RS14365	COG1595	DNA-templated transcription, initiation
M1C60_RS14390	COG1879	ABC-type sugar transport system periplasmic component
M1C60_RS14400	COG1172	Belongs to the binding-protein-dependent transport system permease family
M1C60_RS14410	COG2390	Transcriptional regulator
M1C60_RS14445	COG2329	Antibiotic biosynthesis monooxygenase
M1C60_RS14465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS14475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M1C60_RS14480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_RS14485	COG4187	Peptidase family M20/M25/M40
M1C60_RS14490	COG1414	Transcriptional regulator
M1C60_RS14495	COG0833	amino acid
M1C60_RS14500	COG1690	Belongs to the RtcB family
M1C60_RS14510	COG1785	Belongs to the alkaline phosphatase family
M1C60_RS14520	COG3655	Transcriptional regulator
M1C60_RS14535	COG4377	Putative membrane peptidase family (DUF2324)
M1C60_RS14545	COG3279	Response regulator of the LytR AlgR family
M1C60_RS14555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS14560	COG0346	lactoylglutathione lyase activity
M1C60_RS14580	COG0714	Associated with various cellular activities
M1C60_RS14605	COG0463	Glycosyl transferase, family 2
M1C60_RS14625	COG0463	Glycosyl transferase, family 2
M1C60_RS14635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1C60_RS14640	COG0753	catalase activity
M1C60_RS14650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1C60_RS14675	COG0714	Associated with various cellular activities
M1C60_RS14685	COG0778	Nitroreductase
M1C60_RS14690	COG1846	Transcriptional regulator
M1C60_RS14725	COG1725	Transcriptional regulator
M1C60_RS14735	COG0577	efflux transmembrane transporter activity
M1C60_RS14735	COG1136	(ABC) transporter
M1C60_RS14760	COG2207	Transcriptional regulator
M1C60_RS14765	COG0456	acetyltransferase
M1C60_RS14785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS14805	COG0642	Histidine kinase
M1C60_RS14810	COG0745	RESPONSE REGULATOR receiver
M1C60_RS14815	COG0596	Alpha beta hydrolase
M1C60_RS14845	COG0730	response to heat
M1C60_RS14855	COG0833	amino acid
M1C60_RS14865	COG4335	DNA alkylation repair
M1C60_RS14905	COG0768	penicillin binding
M1C60_RS14915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1C60_RS14950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M1C60_RS14955	COG1414	Transcriptional regulator
M1C60_RS14970	COG0860	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS14975	COG0640	Transcriptional regulator
M1C60_RS14985	COG1960	acyl-CoA dehydrogenase activity
M1C60_RS15000	COG3314	Sporulation integral membrane protein YlbJ
M1C60_RS15015	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M1C60_RS15030	COG3848	Pyruvate phosphate dikinase
M1C60_RS15030	COG0574	Belongs to the PEP-utilizing enzyme family
M1C60_RS15035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS15050	COG5577	PFAM Coat F domain
M1C60_RS15055	COG3403	YqcI/YcgG family
M1C60_RS15060	COG1280	lysine exporter protein (LysE YggA)
M1C60_RS15095	COG1063	alcohol dehydrogenase
M1C60_RS15110	COG1027	Aspartate ammonia-lyase
M1C60_RS15115	COG0252	asparaginase activity
M1C60_RS15120	COG1396	sequence-specific DNA binding
M1C60_RS15130	COG0322	excinuclease ABC activity
M1C60_RS15135	COG0531	amino acid
M1C60_RS15140	COG1114	Component of the transport system for branched-chain amino acids
M1C60_RS15145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_RS15155	COG0281	malic enzyme
M1C60_RS15170	COG0531	amino acid
M1C60_RS15180	COG0784	Response regulator, receiver
M1C60_RS15190	COG2066	Belongs to the glutaminase family
M1C60_RS15195	COG1115	amino acid carrier protein
M1C60_RS15225	COG0737	Belongs to the 5'-nucleotidase family
M1C60_RS15230	COG0753	catalase activity
M1C60_RS15235	COG2267	carboxylic ester hydrolase activity
M1C60_RS15240	COG1335	isochorismatase
M1C60_RS15260	COG0583	DNA-binding transcription factor activity
M1C60_RS15310	COG0415	Belongs to the DNA photolyase family
M1C60_RS15315	COG0288	reversible hydration of carbon dioxide
M1C60_RS15325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1C60_RS15330	COG5609	conserved protein (DUF2294)
M1C60_RS15345	COG1575	Belongs to the MenA family. Type 1 subfamily
M1C60_RS15350	COG2267	carboxylic ester hydrolase activity
M1C60_RS15355	COG0803	Belongs to the bacterial solute-binding protein 9 family
M1C60_RS15360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1C60_RS15365	COG1121	(ABC) transporter
M1C60_RS15395	COG0798	PFAM Bile acid sodium symporter
M1C60_RS15400	COG0346	lactoylglutathione lyase activity
M1C60_RS15405	COG0640	Transcriptional regulator
M1C60_RS15420	COG0443	Heat shock 70 kDa protein
M1C60_RS15435	COG1522	sequence-specific DNA binding
M1C60_RS15450	COG0346	lactoylglutathione lyase activity
M1C60_RS15470	COG2169	Transcriptional regulator
M1C60_RS15475	COG2169	Transcriptional regulator
M1C60_RS15520	COG2814	Major facilitator Superfamily
M1C60_RS15545	COG0745	RESPONSE REGULATOR receiver
M1C60_RS15550	COG3850	Histidine kinase
M1C60_RS15550	COG5002	protein histidine kinase activity
M1C60_RS15575	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1C60_RS15595	COG1476	TRANSCRIPTIONal
M1C60_RS15610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS15615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1C60_RS15625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_RS15630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M1C60_RS15645	COG1136	(ABC) transporter
M1C60_RS15650	COG0577	efflux transmembrane transporter activity
M1C60_RS15665	COG5002	protein histidine kinase activity
M1C60_RS15665	COG3850	Histidine kinase
M1C60_RS15675	COG2364	Membrane
M1C60_RS15680	COG1846	Transcriptional regulator
M1C60_RS15690	COG2808	Putative FMN-binding domain
M1C60_RS15695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS15700	COG2271	Major facilitator Superfamily
M1C60_RS15705	COG1556	Lactate utilization protein
M1C60_RS15710	COG1139	Iron-sulfur cluster binding protein
M1C60_RS15720	COG0583	DNA-binding transcription factor activity
M1C60_RS15730	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1C60_RS15755	COG0673	inositol 2-dehydrogenase activity
M1C60_RS15760	COG0561	phosphatase activity
M1C60_RS15770	COG1609	Transcriptional regulator
M1C60_RS15775	COG0457	Tetratricopeptide repeat
M1C60_RS15795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1C60_RS15825	COG0534	Mate efflux family protein
M1C60_RS15845	COG2814	Major facilitator Superfamily
M1C60_RS15850	COG1309	transcriptional regulator
M1C60_RS15865	COG0814	amino acid
M1C60_RS15870	COG1760	l-serine dehydratase
M1C60_RS15875	COG1760	l-serine dehydratase
M1C60_RS15885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1C60_RS15890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
M1C60_RS15900	COG1335	isochorismatase
M1C60_RS15905	COG1522	sequence-specific DNA binding
M1C60_RS15910	COG0531	amino acid
M1C60_RS15930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1C60_RS15950	COG1595	DNA-templated transcription, initiation
M1C60_RS15965	COG0662	Cupin 2, conserved barrel domain protein
M1C60_RS15970	COG2207	Transcriptional regulator
M1C60_RS15970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS16020	COG0477	Major facilitator Superfamily
M1C60_RS16030	COG1846	Transcriptional regulator
M1C60_RS16035	COG2814	Major facilitator Superfamily
M1C60_RS16045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1C60_RS16050	COG1131	(ABC) transporter
M1C60_RS16070	COG2076	Multidrug Resistance protein
M1C60_RS16075	COG1309	transcriptional regulator
M1C60_RS16085	COG2031	fatty acid transporter
M1C60_RS16095	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1C60_RS16125	COG1122	ATPase activity
M1C60_RS16130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M1C60_RS16145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1C60_RS16150	COG1288	antiporter activity
M1C60_RS16155	COG2356	endonuclease I
M1C60_RS16170	COG3620	sequence-specific DNA binding
M1C60_RS16175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1C60_RS16180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1C60_RS16185	COG0124	histidyl-tRNA synthetase
M1C60_RS16200	COG1733	regulation of RNA biosynthetic process
M1C60_RS16205	COG0778	Nitroreductase
M1C60_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS16235	COG1131	(ABC) transporter
M1C60_RS16260	COG1011	Hydrolase
M1C60_RS16270	COG2365	Tyrosine phosphatase family
M1C60_RS16295	COG0346	lactoylglutathione lyase activity
M1C60_RS16300	COG1940	carbohydrate kinase activity
M1C60_RS16305	COG0738	Major facilitator superfamily
M1C60_RS16310	COG0110	maltose O-acetyltransferase activity
M1C60_RS16320	COG0577	efflux transmembrane transporter activity
M1C60_RS16320	COG1136	(ABC) transporter
M1C60_RS16335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M1C60_RS16340	COG0628	permease
M1C60_RS16360	COG2226	methyltransferase
M1C60_RS16370	COG0477	Major facilitator Superfamily
M1C60_RS16400	COG1253	flavin adenine dinucleotide binding
M1C60_RS16405	COG0789	Transcriptional regulator
M1C60_RS16410	COG0697	spore germination
M1C60_RS16415	COG1357	PFAM Pentapeptide repeats (8 copies)
M1C60_RS16420	COG3813	Protein conserved in bacteria
M1C60_RS16425	COG2706	6-phosphogluconolactonase activity
M1C60_RS16430	COG1070	Carbohydrate kinase
M1C60_RS16440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1C60_RS16445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M1C60_RS16455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1C60_RS16460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M1C60_RS16465	COG0604	alcohol dehydrogenase
M1C60_RS16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1C60_RS16480	COG0604	alcohol dehydrogenase
M1C60_RS16480	COG3321	synthase
M1C60_RS16485	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS16510	COG0656	L-ascorbic acid biosynthetic process
M1C60_RS16515	COG2814	Major facilitator Superfamily
M1C60_RS16530	COG0346	lactoylglutathione lyase activity
M1C60_RS16535	COG0814	amino acid
M1C60_RS16560	COG1393	Belongs to the ArsC family
M1C60_RS16565	COG1733	regulation of RNA biosynthetic process
M1C60_RS16570	COG2188	Transcriptional regulator
M1C60_RS16580	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M1C60_RS16585	COG1733	regulation of RNA biosynthetic process
M1C60_RS16590	COG1733	regulation of RNA biosynthetic process
M1C60_RS16605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS16625	COG0384	phenazine biosynthesis protein PhzF
M1C60_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS16645	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_RS16655	COG1733	regulation of RNA biosynthetic process
M1C60_RS16685	COG1191	sigma factor activity
M1C60_RS16700	COG1309	transcriptional regulator
M1C60_RS16720	COG3152	Membrane
M1C60_RS16745	COG1151	hydroxylamine reductase activity
M1C60_RS16755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS16760	COG3757	hydrolase, family 25
M1C60_RS16760	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_RS16795	COG2072	flavoprotein involved in K transport
M1C60_RS16830	COG0604	alcohol dehydrogenase
M1C60_RS16835	COG1113	amino acid transport
M1C60_RS16840	COG2814	Major facilitator Superfamily
M1C60_RS16870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1C60_RS16875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1C60_RS16900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS16905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS16910	COG3739	integral membrane protein
M1C60_RS16915	COG0384	phenazine biosynthesis protein PhzF
M1C60_RS16945	COG0583	DNA-binding transcription factor activity
M1C60_RS16965	COG1193	negative regulation of DNA recombination
M1C60_RS16995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1C60_RS17025	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_RS17050	COG0640	Transcriptional regulator
M1C60_RS17055	COG0604	alcohol dehydrogenase
M1C60_RS17075	COG2808	Putative FMN-binding domain
M1C60_RS17080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_RS17090	COG0385	Bile acid
M1C60_RS17095	COG0277	FAD linked oxidase domain protein
M1C60_RS17125	COG1216	Glycosyl transferase, family 2
M1C60_RS17130	COG1024	Enoyl-CoA hydratase
M1C60_RS17140	COG1285	pathogenesis
M1C60_RS17155	COG2514	catechol 2,3-dioxygenase activity
M1C60_RS17160	COG2720	vancomycin resistance protein
M1C60_RS17200	COG0716	FMN binding
M1C60_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS17240	COG0165	Argininosuccinate lyase
M1C60_RS17255	COG4145	pantothenate transmembrane transporter activity
M1C60_RS17265	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS17270	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS17280	COG1657	PFAM Prenyltransferase squalene oxidase
M1C60_RS17285	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M1C60_RS17290	COG2962	Rard protein
M1C60_RS17295	COG3326	Membrane
M1C60_RS17310	COG0489	protein tyrosine kinase activity
M1C60_RS17320	COG0314	molybdopterin synthase activity
M1C60_RS17325	COG0303	'Molybdopterin
M1C60_RS17330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_RS17335	COG2116	formate transmembrane transporter activity
M1C60_RS17345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1C60_RS17350	COG5609	conserved protein (DUF2294)
M1C60_RS17355	COG2427	Protein of unknown function (DUF1641)
M1C60_RS17360	COG3383	formate dehydrogenase (NAD+) activity
M1C60_RS17370	COG0697	spore germination
M1C60_RS17410	COG2226	methyltransferase
M1C60_RS17415	COG4166	transmembrane transport
M1C60_RS17425	COG4166	transmembrane transport
M1C60_RS17430	COG1301	dicarboxylic acid transport
M1C60_RS17435	COG1316	TRANSCRIPTIONal
M1C60_RS17445	COG1595	DNA-templated transcription, initiation
M1C60_RS17460	COG1131	(ABC) transporter
M1C60_RS17470	COG0673	inositol 2-dehydrogenase activity
M1C60_RS17475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M1C60_RS17480	COG0187	DNA topoisomerase II activity
M1C60_RS17485	COG1832	CoA-binding protein
M1C60_RS17490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1C60_RS17495	COG0745	RESPONSE REGULATOR receiver
M1C60_RS17510	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M1C60_RS17515	COG4841	protein insertion into membrane
M1C60_RS17520	COG0824	Thioesterase
M1C60_RS17550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_RS17560	COG2274	protein secretion by the type I secretion system
M1C60_RS17565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1C60_RS17605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1C60_RS17620	COG0183	Belongs to the thiolase family
M1C60_RS17625	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_RS17630	COG1268	BioY protein
M1C60_RS17635	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_RS17685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS17695	COG5002	protein histidine kinase activity
M1C60_RS17700	COG0400	carboxylic ester hydrolase activity
M1C60_RS17705	COG0346	lactoylglutathione lyase activity
M1C60_RS17710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1C60_RS17715	COG0069	glutamate synthase activity
M1C60_RS17720	COG1902	pentaerythritol trinitrate reductase activity
M1C60_RS17725	COG1329	Transcriptional regulator
M1C60_RS17730	COG0010	Belongs to the arginase family
M1C60_RS17755	COG2226	methyltransferase
M1C60_RS17790	COG4846	Membrane protein involved in cytochrome C biogenesis
M1C60_RS17795	COG0785	Cytochrome C biogenesis protein
M1C60_RS17805	COG0583	DNA-binding transcription factor activity
M1C60_RS17810	COG1380	Effector of murein hydrolase LrgA
M1C60_RS17815	COG1346	cytolysis
M1C60_RS17840	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS17840	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_RS17855	COG1132	(ABC) transporter
M1C60_RS17860	COG1132	(ABC) transporter
M1C60_RS17890	COG3639	organic phosphonate transmembrane transporter activity
M1C60_RS17895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
M1C60_RS17915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1C60_RS17935	COG1695	Transcriptional regulator
M1C60_RS17980	COG1388	LysM domain
M1C60_RS17980	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_RS17980	COG5632	N-Acetylmuramoyl-L-alanine amidase
M1C60_RS17985	COG4824	toxin secretion phage lysis holin
M1C60_RS18145	COG1595	DNA-templated transcription, initiation
M1C60_RS18190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
M1C60_RS18270	COG1396	sequence-specific DNA binding
M1C60_RS18295	COG0174	glutamine synthetase
M1C60_RS18300	COG0789	Transcriptional regulator
M1C60_RS18305	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M1C60_RS18315	COG2860	membrane
M1C60_RS18320	COG0464	growth
M1C60_RS18350	COG1388	LysM domain
M1C60_RS18350	COG3584	3D domain protein
M1C60_RS18355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1C60_RS18355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1C60_RS18355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1C60_RS18360	COG1105	Belongs to the carbohydrate kinase PfkB family
M1C60_RS18365	COG1349	DNA-binding transcription factor activity
M1C60_RS18375	COG2322	membrane
M1C60_RS18385	COG1113	amino acid transport
M1C60_RS18400	COG1408	metallophosphoesterase
M1C60_RS18405	COG2116	formate transmembrane transporter activity
M1C60_RS18415	COG2217	Heavy metal translocating P-type atpase
M1C60_RS18420	COG2608	mercury ion transmembrane transporter activity
M1C60_RS18425	COG1937	Protein conserved in bacteria
M1C60_RS18435	COG2819	hydrolase of the alpha beta superfamily
M1C60_RS18440	COG1120	ATPase activity
M1C60_RS18445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS18450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS18455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS18460	COG0708	Exodeoxyribonuclease III
M1C60_RS18465	COG2169	Transcriptional regulator
M1C60_RS18470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1C60_RS18475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M1C60_RS18485	COG2364	Membrane
M1C60_RS18500	COG2267	carboxylic ester hydrolase activity
M1C60_RS18505	COG0346	lactoylglutathione lyase activity
M1C60_RS18510	COG5001	Diguanylate cyclase
M1C60_RS18510	COG3300	MHYT domain
M1C60_RS18525	COG1346	cytolysis
M1C60_RS18530	COG1380	Effector of murein hydrolase LrgA
M1C60_RS18535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1C60_RS18540	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_RS18540	COG0596	Alpha beta hydrolase
M1C60_RS18545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M1C60_RS18565	COG1404	Belongs to the peptidase S8 family
M1C60_RS18570	COG3773	Cell wall hydrolase
M1C60_RS18575	COG0562	UDP-galactopyranose mutase
M1C60_RS18580	COG1368	sulfuric ester hydrolase activity
M1C60_RS18585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M1C60_RS18595	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M1C60_RS18620	COG1131	(ABC) transporter
M1C60_RS18640	COG4550	Control of competence regulator ComK, YlbF/YmcA
M1C60_RS18645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1C60_RS18650	COG1013	pyruvate-flavodoxin oxidoreductase activity
M1C60_RS18655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
M1C60_RS18655	COG0674	pyruvate-flavodoxin oxidoreductase activity
M1C60_RS18665	COG2359	stage V sporulation protein S
M1C60_RS18670	COG1692	metallophosphoesterase
M1C60_RS18695	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1C60_RS18700	COG1426	Protein conserved in bacteria
M1C60_RS18715	COG0300	oxidoreductase activity
M1C60_RS18720	COG0612	Peptidase, M16
M1C60_RS18725	COG0612	Peptidase, M16
M1C60_RS18730	COG1079	Belongs to the binding-protein-dependent transport system permease family
M1C60_RS18740	COG3845	ABC transporter
M1C60_RS18745	COG1744	ABC transporter substrate-binding protein PnrA-like
M1C60_RS18750	COG2188	Transcriptional regulator
M1C60_RS18755	COG1674	ftsk spoiiie
M1C60_RS18765	COG0740	serine-type endopeptidase activity
M1C60_RS18770	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1C60_RS18780	COG0527	aspartate kinase activity
M1C60_RS18785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M1C60_RS18790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1C60_RS18795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1C60_RS18800	COG1873	PFAM PRC-barrel domain
M1C60_RS18805	COG0612	Peptidase, M16
M1C60_RS18810	COG0726	polysaccharide deacetylase
M1C60_RS18825	COG0196	riboflavin kinase activity
M1C60_RS18830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1C60_RS18840	COG1550	Protein conserved in bacteria
M1C60_RS18850	COG1358	cellular component organization or biogenesis
M1C60_RS18855	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M1C60_RS18860	COG0195	Participates in both transcription termination and antitermination
M1C60_RS18880	COG0750	zinc metalloprotease
M1C60_RS18890	COG4589	Belongs to the CDS family
M1C60_RS18895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1C60_RS18905	COG0528	UMP kinase activity
M1C60_RS18935	COG4974	Belongs to the 'phage' integrase family
M1C60_RS18945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M1C60_RS18955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M1C60_RS18995	COG1837	Belongs to the UPF0109 family
M1C60_RS19005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1C60_RS19015	COG0552	protein localization to endoplasmic reticulum
M1C60_RS19020	COG1196	nuclear chromosome segregation
M1C60_RS19030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1C60_RS19035	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS19040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1C60_RS19055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1C60_RS19060	COG1461	Dihydroxyacetone kinase
M1C60_RS19065	COG1302	Protein conserved in bacteria
M1C60_RS19080	COG1564	THIamine pyrophosphokinase
M1C60_RS19085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1C60_RS19090	COG1162	GTPase activity
M1C60_RS19095	COG0515	serine threonine protein kinase
M1C60_RS19095	COG2815	serine threonine protein kinase
M1C60_RS19100	COG0631	protein serine/threonine phosphatase activity
M1C60_RS19110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M1C60_RS19110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M1C60_RS19120	COG0242	peptide deformylase activity
M1C60_RS19125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1C60_RS19130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1C60_RS19150	COG1561	YicC-like family, N-terminal region
M1C60_RS19155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1C60_RS19165	COG0006	proline dipeptidase activity
M1C60_RS19180	COG3069	C4-dicarboxylate transmembrane transporter activity
M1C60_RS19245	COG0564	pseudouridine synthase activity
M1C60_RS19265	COG3599	regulation of cell shape
M1C60_RS19270	COG2302	S4 RNA-binding domain
M1C60_RS19275	COG0762	integral membrane protein
M1C60_RS19285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M1C60_RS19290	COG1496	oxidoreductase activity
M1C60_RS19295	COG1873	PFAM PRC-barrel domain
M1C60_RS19300	COG1191	sigma factor activity
M1C60_RS19305	COG1191	sigma factor activity
M1C60_RS19315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1C60_RS19320	COG0849	cell division
M1C60_RS19325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1C60_RS19330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M1C60_RS19340	COG0772	Belongs to the SEDS family
M1C60_RS19355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1C60_RS19360	COG0768	penicillin binding
M1C60_RS19365	COG0768	penicillin binding
M1C60_RS19370	COG4839	cell division protein FtsL
M1C60_RS19385	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M1C60_RS19400	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M1C60_RS19405	COG1399	metal-binding, possibly nucleic acid-binding protein
M1C60_RS19455	COG4824	toxin secretion phage lysis holin
M1C60_RS19550	COG1802	Transcriptional regulator
M1C60_RS19550	COG4626	Terminase
M1C60_RS19575	COG0582	viral genome integration into host DNA
M1C60_RS19640	COG0756	dUTP diphosphatase activity
M1C60_RS19655	COG1191	sigma factor activity
M1C60_RS19680	COG1484	DNA-dependent DNA replication
M1C60_RS19710	COG1396	sequence-specific DNA binding
M1C60_RS19725	COG1396	sequence-specific DNA binding
M1C60_RS19745	COG0582	viral genome integration into host DNA
M1C60_RS19755	COG3480	Lon protease (S16) C-terminal proteolytic domain
M1C60_RS19760	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1C60_RS19765	COG3314	Sporulation integral membrane protein YlbJ
M1C60_RS19775	COG0742	ribosomal rna small subunit methyltransferase
M1C60_RS19790	COG3679	Belongs to the UPF0342 family
M1C60_RS19795	COG0406	alpha-ribazole phosphatase activity
M1C60_RS19810	COG2340	Cysteine-rich secretory protein family
M1C60_RS19825	COG3336	cytochrome c oxidase
M1C60_RS19860	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M1C60_RS19865	COG0772	Belongs to the SEDS family
M1C60_RS19875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M1C60_RS19880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M1C60_RS19890	COG4896	Protein conserved in bacteria
M1C60_RS19905	COG1217	gtp-binding protein TYPA
M1C60_RS19915	COG0483	inositol monophosphate 1-phosphatase activity
M1C60_RS19935	COG1982	Orn Lys Arg decarboxylase major
M1C60_RS19980	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_RS19985	COG0022	dehydrogenase e1 component
M1C60_RS19990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1C60_RS20000	COG0242	peptide deformylase activity
M1C60_RS20005	COG0561	phosphatase activity
M1C60_RS20015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M1C60_RS20020	COG0569	domain protein
M1C60_RS20040	COG0583	DNA-binding transcription factor activity
M1C60_RS20045	COG0517	IMP dehydrogenase activity
M1C60_RS20055	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M1C60_RS20065	COG4703	Protein of unknown function (DUF1797)
M1C60_RS20080	COG2200	EAL domain
M1C60_RS20085	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS20090	COG1408	metallophosphoesterase
M1C60_RS20100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
M1C60_RS20135	COG2814	Major facilitator Superfamily
M1C60_RS20155	COG3209	COG3209 Rhs family protein
M1C60_RS20165	COG2205	protein histidine kinase activity
M1C60_RS20175	COG0436	Aminotransferase
M1C60_RS20180	COG1609	Transcriptional regulator
M1C60_RS20185	COG3833	ABC-type maltose transport systems, permease component
M1C60_RS20190	COG1175	transmembrane transport
M1C60_RS20195	COG2182	Extracellular solute-binding protein
M1C60_RS20205	COG0366	Alpha amylase catalytic
M1C60_RS20210	COG3842	ATPase activity
M1C60_RS20250	COG0183	Belongs to the thiolase family
M1C60_RS20285	COG1695	Transcriptional regulator
M1C60_RS20290	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS20300	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M1C60_RS20310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1C60_RS20315	COG0436	Aminotransferase
M1C60_RS20335	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
M1C60_RS20355	COG2199	diguanylate cyclase activity
M1C60_RS20360	COG0778	Nitroreductase
M1C60_RS20385	COG2190	(PTS) system
M1C60_RS20385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M1C60_RS20385	COG1263	PTS System
M1C60_RS20390	COG3711	transcriptional antiterminator
M1C60_RS20400	COG2188	Transcriptional regulator
M1C60_RS20410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M1C60_RS20435	COG1547	Domain of unknown function (DUF309)
M1C60_RS20440	COG0456	acetyltransferase
M1C60_RS20450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1C60_RS20455	COG4086	secreted protein
M1C60_RS20460	COG0561	phosphatase activity
M1C60_RS20465	COG0697	spore germination
M1C60_RS20480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_RS20505	COG0733	neurotransmitter:sodium symporter activity
M1C60_RS20525	COG1686	Belongs to the peptidase S11 family
M1C60_RS20530	COG1725	Transcriptional regulator
M1C60_RS20535	COG1131	(ABC) transporter
M1C60_RS20550	COG1846	Transcriptional regulator
M1C60_RS20565	COG0598	Magnesium transport protein CorA
M1C60_RS20590	COG4974	Belongs to the 'phage' integrase family
M1C60_RS20600	COG0735	belongs to the Fur family
M1C60_RS20605	COG1300	Membrane
M1C60_RS20625	COG0667	Aldo Keto reductase
M1C60_RS20630	COG0656	L-ascorbic acid biosynthetic process
M1C60_RS20635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1C60_RS20635	COG0456	acetyltransferase
M1C60_RS20645	COG1525	nuclease
M1C60_RS20645	COG4085	toxin activity
M1C60_RS20645	COG0737	Belongs to the 5'-nucleotidase family
M1C60_RS20655	COG0596	Alpha beta hydrolase
M1C60_RS20660	COG2056	Na+-H+ antiporter family
M1C60_RS20665	COG1609	Transcriptional regulator
M1C60_RS20670	COG0456	acetyltransferase
M1C60_RS20675	COG1073	alpha beta
M1C60_RS20690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1C60_RS20690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1C60_RS20695	COG0307	riboflavin synthase, alpha
M1C60_RS20720	COG4106	trans-aconitate 2-methyltransferase activity
M1C60_RS20725	COG1073	alpha beta
M1C60_RS20725	COG2226	methyltransferase
M1C60_RS20740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M1C60_RS20750	COG1757	Na H antiporter
M1C60_RS20755	COG0737	Belongs to the 5'-nucleotidase family
M1C60_RS20765	COG1522	sequence-specific DNA binding
M1C60_RS20785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1C60_RS20795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1C60_RS20810	COG0300	oxidoreductase activity
M1C60_RS20820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_RS20825	COG1760	l-serine dehydratase
M1C60_RS20830	COG1760	l-serine dehydratase
M1C60_RS20850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1C60_RS20860	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1C60_RS20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS20880	COG1376	ErfK ybiS ycfS ynhG family protein
M1C60_RS20885	COG4129	membrane
M1C60_RS20890	COG1126	abc transporter atp-binding protein
M1C60_RS20895	COG0765	amino acid transport
M1C60_RS20900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1C60_RS20915	COG2816	NAD+ diphosphatase activity
M1C60_RS20920	COG0772	Belongs to the SEDS family
M1C60_RS20925	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1C60_RS20930	COG0022	dehydrogenase e1 component
M1C60_RS20935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1C60_RS20940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1C60_RS20955	COG0280	phosphate acetyltransferase
M1C60_RS20960	COG3290	protein histidine kinase activity
M1C60_RS20960	COG3829	transcription factor binding
M1C60_RS20970	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_RS20975	COG3093	addiction module antidote protein HigA
M1C60_RS20985	COG0745	RESPONSE REGULATOR receiver
M1C60_RS20990	COG0750	zinc metalloprotease
M1C60_RS20995	COG0497	DNA recombination
M1C60_RS21005	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M1C60_RS21015	COG0142	geranyltranstransferase activity
M1C60_RS21040	COG1302	Protein conserved in bacteria
M1C60_RS21045	COG0439	Biotin carboxylase
M1C60_RS21050	COG0511	ligase activity, forming carbon-carbon bonds
M1C60_RS21095	COG3854	ATPases associated with a variety of cellular activities
M1C60_RS21120	COG0006	proline dipeptidase activity
M1C60_RS21135	COG3872	metal-dependent enzyme
M1C60_RS21145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1C60_RS21165	COG0095	Lipoate-protein ligase
M1C60_RS21170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_RS21175	COG1609	Transcriptional regulator
M1C60_RS21185	COG2076	Multidrug Resistance protein
M1C60_RS21190	COG2076	Multidrug Resistance protein
M1C60_RS21230	COG1725	Transcriptional regulator
M1C60_RS21260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M1C60_RS21320	COG4970	Tfp pilus assembly protein FimT
M1C60_RS21330	COG1459	type II secretion system
M1C60_RS21335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1C60_RS21385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M1C60_RS21390	COG0646	methionine synthase
M1C60_RS21390	COG1410	methionine synthase
M1C60_RS21395	COG0646	methionine synthase
M1C60_RS21395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1C60_RS21400	COG0626	cystathionine gamma-synthase activity
M1C60_RS21405	COG0626	cystathionine gamma-synthase activity
M1C60_RS21425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS21435	COG1940	carbohydrate kinase activity
M1C60_RS21440	COG4483	Protein conserved in bacteria
M1C60_RS21445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1C60_RS21450	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M1C60_RS21455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1C60_RS21460	COG0704	Plays a role in the regulation of phosphate uptake
M1C60_RS21470	COG0581	inorganic phosphate transmembrane transporter activity
M1C60_RS21475	COG0573	inorganic phosphate transmembrane transporter activity
M1C60_RS21480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1C60_RS21485	COG0768	penicillin binding
M1C60_RS21490	COG0477	Major facilitator Superfamily
M1C60_RS21495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1C60_RS21520	COG0735	belongs to the Fur family
M1C60_RS21525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1C60_RS21530	COG1121	(ABC) transporter
M1C60_RS21535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS21565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1C60_RS21570	COG2384	SAM-dependent methyltransferase
M1C60_RS21575	COG2010	Cytochrome c
M1C60_RS21580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M1C60_RS21585	COG0358	DNA primase activity
M1C60_RS21595	COG0517	IMP dehydrogenase activity
M1C60_RS21610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1C60_RS21615	COG0295	cytidine deaminase activity
M1C60_RS21620	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M1C60_RS21630	COG1480	7TM receptor with intracellular HD hydrolase
M1C60_RS21635	COG1702	phosphate starvation-inducible protein PhoH
M1C60_RS21650	COG1610	YqeY-like protein
M1C60_RS21655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M1C60_RS21660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M1C60_RS21665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1C60_RS21695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1C60_RS21700	COG1733	regulation of RNA biosynthetic process
M1C60_RS21725	COG1466	dna polymerase III delta subunit
M1C60_RS21735	COG2333	competence protein COMEC
M1C60_RS21735	COG0658	competence protein
M1C60_RS21740	COG2131	deaminase
M1C60_RS21745	COG1555	photosystem II stabilization
M1C60_RS21745	COG1596	polysaccharide export
M1C60_RS21750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M1C60_RS21755	COG2226	methyltransferase
M1C60_RS21760	COG0799	negative regulation of ribosome biogenesis
M1C60_RS21765	COG1713	HD superfamily hydrolase involved in NAD metabolism
M1C60_RS21775	COG1534	Rna-binding protein
M1C60_RS21785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M1C60_RS21790	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M1C60_RS21815	COG1595	DNA-templated transcription, initiation
M1C60_RS21825	COG0778	Nitroreductase
M1C60_RS21830	COG2357	RelA SpoT domain protein
M1C60_RS21840	COG1785	Belongs to the alkaline phosphatase family
M1C60_RS21850	COG2267	carboxylic ester hydrolase activity
M1C60_RS21885	COG1404	Belongs to the peptidase S8 family
M1C60_RS21890	COG3186	Phenylalanine-4-hydroxylase
M1C60_RS21905	COG2259	Doxx family
M1C60_RS21945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS21955	COG1454	alcohol dehydrogenase
M1C60_RS21955	COG1012	belongs to the aldehyde dehydrogenase family
M1C60_RS21960	COG0626	cystathionine gamma-synthase activity
M1C60_RS21965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1C60_RS21990	COG0768	penicillin binding
M1C60_RS22005	COG0826	peptidase U32
M1C60_RS22010	COG0826	peptidase U32
M1C60_RS22015	COG4122	O-methyltransferase activity
M1C60_RS22020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1C60_RS22040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M1C60_RS22050	COG0628	permease
M1C60_RS22070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1C60_RS22080	COG0482	sulfurtransferase activity
M1C60_RS22085	COG1104	cysteine desulfurase activity
M1C60_RS22090	COG1959	2 iron, 2 sulfur cluster binding
M1C60_RS22095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1C60_RS22105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1C60_RS22130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1C60_RS22140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M1C60_RS22140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1C60_RS22145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M1C60_RS22150	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1C60_RS22150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1C60_RS22160	COG2244	polysaccharide biosynthetic process
M1C60_RS22165	COG2323	membrane
M1C60_RS22175	COG1862	Preprotein translocase
M1C60_RS22205	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M1C60_RS22215	COG0697	spore germination
M1C60_RS22220	COG0697	spore germination
M1C60_RS22225	COG0640	Transcriptional regulator
M1C60_RS22250	COG0157	Belongs to the NadC ModD family
M1C60_RS22255	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M1C60_RS22260	COG1104	cysteine desulfurase activity
M1C60_RS22265	COG1827	regulation of RNA biosynthetic process
M1C60_RS22270	COG2258	MOSC domain
M1C60_RS22275	COG0077	Prephenate dehydratase
M1C60_RS22280	COG0577	efflux transmembrane transporter activity
M1C60_RS22285	COG0577	efflux transmembrane transporter activity
M1C60_RS22290	COG1136	(ABC) transporter
M1C60_RS22300	COG0745	RESPONSE REGULATOR receiver
M1C60_RS22305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M1C60_RS22310	COG3290	protein histidine kinase activity
M1C60_RS22320	COG2868	ribosomal protein
M1C60_RS22330	COG1530	ribonuclease E activity
M1C60_RS22335	COG1994	Peptidase M50
M1C60_RS22340	COG0739	heme binding
M1C60_RS22345	COG2894	cell division
M1C60_RS22365	COG1077	Cell shape determining protein MreB Mrl
M1C60_RS22385	COG0285	dihydrofolate synthase activity
M1C60_RS22390	COG0525	valine-tRNA ligase activity
M1C60_RS22400	COG1388	LysM domain
M1C60_RS22410	COG0113	porphobilinogen synthase activity
M1C60_RS22415	COG1587	Uroporphyrinogen-III synthase
M1C60_RS22425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M1C60_RS22435	COG1846	Transcriptional regulator
M1C60_RS22440	COG1764	response to oxidative stress
M1C60_RS22455	COG0470	DNA polymerase III
M1C60_RS22455	COG1067	ATP-dependent peptidase activity
M1C60_RS22500	COG0622	Phosphoesterase
M1C60_RS22515	COG5401	PFAM Sporulation and spore germination
M1C60_RS22535	COG1309	transcriptional regulator
M1C60_RS22550	COG2197	response regulator
M1C60_RS22555	COG2233	PERMEase
M1C60_RS22565	COG0402	S-adenosylhomocysteine deaminase activity
M1C60_RS22570	COG0402	S-adenosylhomocysteine deaminase activity
M1C60_RS22580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1C60_RS22590	COG0444	Belongs to the ABC transporter superfamily
M1C60_RS22595	COG4608	Belongs to the ABC transporter superfamily
M1C60_RS22600	COG3275	phosphorelay sensor kinase activity
M1C60_RS22605	COG3279	Response regulator of the LytR AlgR family
M1C60_RS22620	COG1983	PspC domain protein
M1C60_RS22625	COG1396	sequence-specific DNA binding
M1C60_RS22630	COG0697	spore germination
M1C60_RS22640	COG1959	2 iron, 2 sulfur cluster binding
M1C60_RS22645	COG1668	transmembrane transport
M1C60_RS22650	COG4152	abc transporter atp-binding protein
M1C60_RS22655	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M1C60_RS22665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M1C60_RS22670	COG1876	peptidase activity
M1C60_RS22675	COG0824	Thioesterase
M1C60_RS22680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1C60_RS22685	COG1053	succinate dehydrogenase
M1C60_RS22690	COG2009	succinate dehydrogenase
M1C60_RS22695	COG1719	4-vinyl reductase, 4VR
M1C60_RS22705	COG3118	belongs to the thioredoxin family
M1C60_RS22710	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M1C60_RS22715	COG2086	electron transfer activity
M1C60_RS22720	COG1024	Enoyl-CoA hydratase
M1C60_RS22730	COG0318	PFAM AMP-dependent synthetase and ligase
M1C60_RS22750	COG2318	DinB family
M1C60_RS22780	COG1131	(ABC) transporter
M1C60_RS22785	COG2205	protein histidine kinase activity
M1C60_RS22790	COG0745	RESPONSE REGULATOR receiver
M1C60_RS22800	COG4895	conserved protein (DUF2196)
M1C60_RS22805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M1C60_RS22820	COG4509	Sortase family
M1C60_RS22825	COG1120	ATPase activity
M1C60_RS22840	COG5386	Cell surface protein
M1C60_RS22850	COG5386	Cell surface protein
M1C60_RS22855	COG1114	Component of the transport system for branched-chain amino acids
M1C60_RS22860	COG1187	pseudouridine synthase activity
M1C60_RS22870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M1C60_RS22870	COG1796	DNA polymerase
M1C60_RS22875	COG1286	toxin biosynthetic process
M1C60_RS22920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1C60_RS22930	COG1418	mRNA catabolic process
M1C60_RS22955	COG2814	Major facilitator Superfamily
M1C60_RS22960	COG1566	PFAM secretion protein HlyD family protein
M1C60_RS22965	COG1309	transcriptional regulator
M1C60_RS22970	COG1363	Peptidase, m42
M1C60_RS22995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M1C60_RS23005	COG1484	DNA-dependent DNA replication
M1C60_RS23010	COG3611	Membrane attachment protein
M1C60_RS23020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M1C60_RS23025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1C60_RS23030	COG0237	dephospho-CoA kinase activity
M1C60_RS23035	COG1971	Probably functions as a manganese efflux pump
M1C60_RS23045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1C60_RS23045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M1C60_RS23050	COG5002	protein histidine kinase activity
M1C60_RS23055	COG0745	RESPONSE REGULATOR receiver
M1C60_RS23080	COG0538	isocitrate dehydrogenase activity
M1C60_RS23085	COG0372	Belongs to the citrate synthase family
M1C60_RS23095	COG0628	permease
M1C60_RS23100	COG3030	protein affecting phage T7 exclusion by the F plasmid
M1C60_RS23125	COG1725	Transcriptional regulator
M1C60_RS23130	COG0281	malic enzyme
M1C60_RS23135	COG0587	DNA-directed DNA polymerase activity
M1C60_RS23150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M1C60_RS23170	COG4109	DRTGG domain
M1C60_RS23185	COG0006	proline dipeptidase activity
M1C60_RS23225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS23230	COG0662	Cupin 2, conserved barrel domain protein
M1C60_RS23240	COG1476	TRANSCRIPTIONal
M1C60_RS23255	COG1028	Short-chain dehydrogenase reductase Sdr
M1C60_RS23260	COG0589	response to stress
M1C60_RS23300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS23320	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1C60_RS23325	COG0827	DNA restriction-modification system
M1C60_RS23330	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M1C60_RS23335	COG3874	Sporulation protein YtfJ
M1C60_RS23350	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M1C60_RS23360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1C60_RS23375	COG1104	cysteine desulfurase activity
M1C60_RS23385	COG0583	DNA-binding transcription factor activity
M1C60_RS23390	COG0697	spore germination
M1C60_RS23400	COG1956	GAF domain-containing protein
M1C60_RS23405	COG0626	cystathionine gamma-synthase activity
M1C60_RS23435	COG1595	DNA-templated transcription, initiation
M1C60_RS23445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1C60_RS23450	COG0454	-acetyltransferase
M1C60_RS23455	COG0517	IMP dehydrogenase activity
M1C60_RS23460	COG0123	including yeast histone deacetylase and acetoin utilization protein
M1C60_RS23470	COG0745	RESPONSE REGULATOR receiver
M1C60_RS23480	COG0666	response to abiotic stimulus
M1C60_RS23515	COG1609	Transcriptional regulator
M1C60_RS23520	COG4851	CamS sex pheromone cAM373 precursor
M1C60_RS23525	COG3118	belongs to the thioredoxin family
M1C60_RS23535	COG2309	aminopeptidase activity
M1C60_RS23555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS23570	COG1674	ftsk spoiiie
M1C60_RS23580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1C60_RS23585	COG4848	Belongs to the UPF0354 family
M1C60_RS23590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_RS23595	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
M1C60_RS23600	COG1363	Peptidase, m42
M1C60_RS23610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS23625	COG0510	thiamine kinase activity
M1C60_RS23630	COG1523	belongs to the glycosyl hydrolase 13 family
M1C60_RS23645	COG1349	DNA-binding transcription factor activity
M1C60_RS23650	COG1187	pseudouridine synthase activity
M1C60_RS23655	COG2244	polysaccharide biosynthetic process
M1C60_RS23660	COG2081	HI0933 family
M1C60_RS23665	COG2814	Major facilitator Superfamily
M1C60_RS23675	COG3832	glyoxalase III activity
M1C60_RS23695	COG1329	Transcriptional regulator
M1C60_RS23705	COG4975	Glucose uptake
M1C60_RS23720	COG0314	molybdopterin synthase activity
M1C60_RS23725	COG1763	Mo-molybdopterin cofactor biosynthetic process
M1C60_RS23730	COG0303	'Molybdopterin
M1C60_RS23740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M1C60_RS23765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M1C60_RS23775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1C60_RS23815	COG2814	Major facilitator Superfamily
M1C60_RS23820	COG0475	glutathione-regulated potassium exporter activity
M1C60_RS23825	COG0490	domain, Protein
M1C60_RS23830	COG0582	viral genome integration into host DNA
M1C60_RS23840	COG1136	(ABC) transporter
M1C60_RS23860	COG1242	4 iron, 4 sulfur cluster binding
M1C60_RS23865	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M1C60_RS23870	COG1131	(ABC) transporter
M1C60_RS23880	COG1794	racemase activity, acting on amino acids and derivatives
M1C60_RS23900	COG2267	carboxylic ester hydrolase activity
M1C60_RS23905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1C60_RS23910	COG0671	phosphoesterase, PA-phosphatase related
M1C60_RS23915	COG0438	transferase activity, transferring glycosyl groups
M1C60_RS23925	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1C60_RS23980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1C60_RS23985	COG5002	protein histidine kinase activity
M1C60_RS23995	COG2267	carboxylic ester hydrolase activity
M1C60_RS24015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1C60_RS24020	COG1116	anion transmembrane transporter activity
M1C60_RS24025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1C60_RS24050	COG0494	nUDIX hydrolase
M1C60_RS24085	COG0288	reversible hydration of carbon dioxide
M1C60_RS24090	COG1271	oxidase subunit
M1C60_RS24095	COG1294	oxidase, subunit
M1C60_RS24115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS24140	COG1842	Phage shock protein A
M1C60_RS24170	COG5002	protein histidine kinase activity
M1C60_RS24175	COG0745	RESPONSE REGULATOR receiver
M1C60_RS24205	COG1597	lipid kinase activity
M1C60_RS24240	COG0586	Pfam SNARE associated Golgi protein
M1C60_RS24250	COG0577	efflux transmembrane transporter activity
M1C60_RS24255	COG1136	(ABC) transporter
M1C60_RS24260	COG3708	Transcriptional regulator
M1C60_RS24260	COG2207	Transcriptional regulator
M1C60_RS24265	COG0745	RESPONSE REGULATOR receiver
M1C60_RS24270	COG2205	protein histidine kinase activity
M1C60_RS24280	COG0577	efflux transmembrane transporter activity
M1C60_RS24285	COG1136	(ABC) transporter
M1C60_RS24305	COG2188	Transcriptional regulator
M1C60_RS24325	COG3964	amidohydrolase
M1C60_RS24355	COG4948	Mandelate Racemase Muconate Lactonizing
M1C60_RS24365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M1C60_RS24370	COG0596	Alpha beta hydrolase
M1C60_RS24375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M1C60_RS24380	COG1169	isochorismate synthase
M1C60_RS24385	COG1575	Belongs to the MenA family. Type 1 subfamily
M1C60_RS24390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1C60_RS24415	COG0058	SHG alpha-glucan phosphorylase activity
M1C60_RS24420	COG0297	glycogen (starch) synthase activity
M1C60_RS24425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M1C60_RS24540	COG0544	peptidyl-prolyl cis-trans isomerase activity
M1C60_RS24575	COG1285	pathogenesis
M1C60_RS24580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1C60_RS24590	COG0166	Belongs to the GPI family
M1C60_RS24595	COG2155	Conserved Protein
M1C60_RS24600	COG1098	S1 RNA binding domain
M1C60_RS24605	COG0436	Aminotransferase
M1C60_RS24610	COG1522	sequence-specific DNA binding
M1C60_RS24615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M1C60_RS24620	COG2267	carboxylic ester hydrolase activity
M1C60_RS24630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M1C60_RS24650	COG5018	Exonuclease
M1C60_RS24655	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1C60_RS24675	COG2050	protein possibly involved in aromatic compounds catabolism
M1C60_RS24685	COG1268	BioY protein
M1C60_RS24695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1C60_RS24700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1C60_RS24715	COG3584	3D domain protein
M1C60_RS24730	COG1252	NADH dehydrogenase
M1C60_RS24745	COG3708	Transcriptional regulator
M1C60_RS24760	COG1683	Conserved Protein
M1C60_RS24780	COG0316	Belongs to the HesB IscA family
M1C60_RS24795	COG1252	NADH dehydrogenase
M1C60_RS24810	COG0390	transport system, permease component
M1C60_RS24815	COG2824	Alkylphosphonate utilization operon protein PhnA
M1C60_RS24855	COG4837	Protein of unknown function (DUF1462)
M1C60_RS24860	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M1C60_RS24870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1C60_RS24875	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1C60_RS24885	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1C60_RS24890	COG0647	UMP catabolic process
M1C60_RS24900	COG2445	Protein of unknown function DUF86
M1C60_RS24905	COG1494	fructose-1,6-bisphosphatase
M1C60_RS24920	COG4470	Protein conserved in bacteria
M1C60_RS24930	COG0789	Transcriptional regulator
M1C60_RS24935	COG4377	Putative membrane peptidase family (DUF2324)
M1C60_RS24960	COG0739	heme binding
M1C60_RS24970	COG3377	Domain of unknown function (DUF1805)
M1C60_RS24975	COG0737	Belongs to the 5'-nucleotidase family
M1C60_RS24980	COG1695	Transcriptional regulator
M1C60_RS24990	COG0719	Fe-S assembly protein
M1C60_RS24995	COG0822	iron-sulfur transferase activity
M1C60_RS25000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1C60_RS25005	COG0719	Fe-S assembly protein
M1C60_RS25010	COG0396	ATPase activity
M1C60_RS25015	COG1464	Belongs to the NlpA lipoprotein family
M1C60_RS25020	COG1464	Belongs to the NlpA lipoprotein family
M1C60_RS25025	COG2011	ABC-type metal ion transport system permease component
M1C60_RS25030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1C60_RS25040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M1C60_RS25045	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M1C60_RS25055	COG1393	Belongs to the ArsC family
M1C60_RS25100	COG0039	L-malate dehydrogenase activity
M1C60_RS25125	COG1309	transcriptional regulator
M1C60_RS25130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1C60_RS25135	COG1960	acyl-CoA dehydrogenase activity
M1C60_RS25140	COG0183	Belongs to the thiolase family
M1C60_RS25145	COG1024	Enoyl-CoA hydratase
M1C60_RS25145	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1C60_RS25155	COG1686	Belongs to the peptidase S11 family
M1C60_RS25170	COG0011	TIGRFAM Protein of
M1C60_RS25175	COG0840	transmembrane signaling receptor activity
M1C60_RS25195	COG2814	Major facilitator Superfamily
M1C60_RS25200	COG0531	amino acid
M1C60_RS25210	COG0706	membrane insertase activity
M1C60_RS25220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M1C60_RS25255	COG0586	Pfam SNARE associated Golgi protein
M1C60_RS25265	COG1376	ErfK ybiS ycfS ynhG family protein
M1C60_RS25270	COG0745	RESPONSE REGULATOR receiver
M1C60_RS25275	COG5002	protein histidine kinase activity
M1C60_RS25300	COG2151	metal-sulfur cluster biosynthetic enzyme
M1C60_RS25305	COG3227	Zinc metalloprotease (Elastase)
M1C60_RS25310	COG1741	Belongs to the pirin family
M1C60_RS25325	COG0475	glutathione-regulated potassium exporter activity
M1C60_RS25330	COG0490	domain, Protein
M1C60_RS25335	COG1115	amino acid carrier protein
M1C60_RS25340	COG0783	Belongs to the Dps family
M1C60_RS25355	COG1611	Belongs to the LOG family
M1C60_RS25375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS25380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS25385	COG1115	amino acid carrier protein
M1C60_RS25390	COG1115	amino acid carrier protein
M1C60_RS25395	COG2910	NAD(P)H-binding
M1C60_RS25410	COG0656	L-ascorbic acid biosynthetic process
M1C60_RS25415	COG2814	Major facilitator Superfamily
M1C60_RS25420	COG1733	regulation of RNA biosynthetic process
M1C60_RS25430	COG1252	NADH dehydrogenase
M1C60_RS25435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1C60_RS25440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M1C60_RS25450	COG0840	transmembrane signaling receptor activity
M1C60_RS25450	COG3290	protein histidine kinase activity
M1C60_RS25460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1C60_RS25465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M1C60_RS25480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M1C60_RS25535	COG0557	exoribonuclease II activity
M1C60_RS25540	COG1647	Serine aminopeptidase, S33
M1C60_RS25545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M1C60_RS25550	COG1346	cytolysis
M1C60_RS25650	COG4695	Portal protein
M1C60_RS25675	COG4974	Belongs to the 'phage' integrase family
M1C60_RS25685	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1C60_RS25690	COG0149	triose-phosphate isomerase activity
M1C60_RS25700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1C60_RS25715	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M1C60_RS25740	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M1C60_RS25755	COG2323	membrane
M1C60_RS25760	COG0740	serine-type endopeptidase activity
M1C60_RS25765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1C60_RS25775	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M1C60_RS25785	COG1051	belongs to the nudix hydrolase family
M1C60_RS25795	COG0492	ferredoxin-NADP+ reductase activity
M1C60_RS25800	COG0457	Tetratricopeptide repeat
M1C60_RS25805	COG0110	maltose O-acetyltransferase activity
M1C60_RS25825	COG1950	PFAM Membrane protein of
M1C60_RS25835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1C60_RS25840	COG0556	nucleotide-excision repair
M1C60_RS25860	COG0789	Transcriptional regulator
M1C60_RS25885	COG2855	membrane
M1C60_RS25890	COG0583	DNA-binding transcription factor activity
M1C60_RS25900	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1C60_RS25905	COG0488	(ABC) transporter
M1C60_RS25915	COG1132	(ABC) transporter
M1C60_RS25920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1C60_RS25925	COG0793	Belongs to the peptidase S41A family
M1C60_RS25925	COG3409	Peptidoglycan-binding domain 1 protein
M1C60_RS25930	COG2177	Part of the ABC transporter FtsEX involved in
M1C60_RS25935	COG2884	Cell division ATP-binding protein ftsE
M1C60_RS25950	COG0653	protein targeting
M1C60_RS25955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M1C60_RS25960	COG1278	Cold shock
M1C60_RS25965	COG1040	competence protein
M1C60_RS25970	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M1C60_RS25975	COG0791	NLP P60 protein
M1C60_RS25975	COG1388	LysM domain
M1C60_RS25980	COG1733	regulation of RNA biosynthetic process
M1C60_RS25985	COG1307	EDD domain protein, DegV family
M1C60_RS25990	COG1739	Uncharacterized protein family UPF0029
M1C60_RS25995	COG1316	TRANSCRIPTIONal
M1C60_RS26000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1C60_RS26005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1C60_RS26010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M1C60_RS26020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M1C60_RS26020	COG3933	PFAM sigma-54 factor interaction domain-containing protein
M1C60_RS26035	COG3394	polysaccharide catabolic process
M1C60_RS26040	COG1486	melibiose metabolic process
M1C60_RS26045	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1C60_RS26050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1C60_RS26060	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M1C60_RS26065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M1C60_RS26070	COG1447	Phosphotransferase system cellobiose-specific component IIA
M1C60_RS26080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M1C60_RS26085	COG1301	dicarboxylic acid transport
M1C60_RS26095	COG0346	lactoylglutathione lyase activity
M1C60_RS26100	COG1511	domain protein
M1C60_RS26105	COG0583	DNA-binding transcription factor activity
M1C60_RS26110	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M1C60_RS26125	COG1271	oxidase subunit
M1C60_RS26130	COG1294	oxidase, subunit
M1C60_RS26135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M1C60_RS26145	COG1620	l-lactate permease
M1C60_RS26155	COG2389	metal-binding protein
M1C60_RS26165	COG1368	sulfuric ester hydrolase activity
M1C60_RS26180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M1C60_RS26190	COG1215	transferase activity, transferring glycosyl groups
M1C60_RS26200	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1C60_RS26205	COG1388	LysM domain
M1C60_RS26205	COG3584	3D domain protein
M1C60_RS26230	COG4715	Zinc finger, swim domain protein
M1C60_RS26275	COG0577	efflux transmembrane transporter activity
M1C60_RS26280	COG1136	(ABC) transporter
M1C60_RS26315	COG5002	protein histidine kinase activity
M1C60_RS26320	COG0745	RESPONSE REGULATOR receiver
M1C60_RS26325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1C60_RS26345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M1C60_RS26350	COG1134	teichoic acid transport
M1C60_RS26355	COG1682	transport, permease protein
M1C60_RS26360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1C60_RS26405	COG1609	Transcriptional regulator
M1C60_RS26420	COG0739	heme binding
M1C60_RS26440	COG2385	sporulation resulting in formation of a cellular spore
M1C60_RS26455	COG4836	Membrane
M1C60_RS26460	COG1007	ATP synthesis coupled electron transport
M1C60_RS26465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1C60_RS26470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1C60_RS26480	COG0839	Belongs to the complex I subunit 6 family
M1C60_RS26495	COG0649	NAD binding
M1C60_RS26500	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1C60_RS26515	COG3300	MHYT domain
M1C60_RS26515	COG5001	Diguanylate cyclase
M1C60_RS26565	COG0356	it plays a direct role in the translocation of protons across the membrane
M1C60_RS26600	COG0698	ribose 5-phosphate isomerase
M1C60_RS26610	COG2190	(PTS) system
M1C60_RS26615	COG2259	Doxx family
M1C60_RS26620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1C60_RS26635	COG0009	L-threonylcarbamoyladenylate synthase
M1C60_RS26650	COG2890	protein-(glutamine-N5) methyltransferase activity
M1C60_RS26670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M1C60_RS26675	COG1494	fructose-1,6-bisphosphatase
M1C60_RS26695	COG4821	SIS domain
M1C60_RS26705	COG3343	RNA polymerase activity
M1C60_RS26715	COG1960	acyl-CoA dehydrogenase activity
M1C60_RS26720	COG1960	acyl-CoA dehydrogenase activity
M1C60_RS26725	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1C60_RS26730	COG0183	Belongs to the thiolase family
M1C60_RS26735	COG0247	lactate metabolic process
M1C60_RS26735	COG2181	nitrate reductase activity
M1C60_RS26740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1C60_RS26750	COG5001	Diguanylate cyclase
M1C60_RS26750	COG3300	MHYT domain
M1C60_RS26770	COG2197	response regulator
M1C60_RS26775	COG4585	Histidine kinase
M1C60_RS26780	COG0842	Transport permease protein
M1C60_RS26785	COG1131	(ABC) transporter
M1C60_RS26790	COG0024	Methionine aminopeptidase
M1C60_RS26800	COG2234	aminopeptidase activity
M1C60_RS26820	COG1595	DNA-templated transcription, initiation
M1C60_RS26825	COG0018	arginyl-trna synthetase
M1C60_RS26830	COG4506	Protein conserved in bacteria
M1C60_RS26835	COG1619	proteins homologs of microcin C7 resistance protein MccF
M1C60_RS26850	COG0010	Belongs to the arginase family
M1C60_RS26860	COG2814	Major facilitator Superfamily
M1C60_RS26865	COG0789	Transcriptional regulator
M1C60_RS26870	COG0584	glycerophosphoryl diester phosphodiesterase
M1C60_RS26875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1C60_RS26885	COG1994	Peptidase M50
M1C60_RS26895	COG1078	dGTPase activity
M1C60_RS26900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M1C60_RS26905	COG1120	ATPase activity
M1C60_RS26910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1C60_RS26935	COG0095	Lipoate-protein ligase
M1C60_RS26940	COG0280	phosphate acetyltransferase
M1C60_RS26955	COG3773	Cell wall hydrolase
M1C60_RS26965	COG2363	Small membrane protein
M1C60_RS26975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1C60_RS26980	COG2233	PERMEase
M1C60_RS26985	COG0561	phosphatase activity
M1C60_RS26990	COG2814	Major facilitator Superfamily
M1C60_RS27000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M1C60_RS27005	COG1131	(ABC) transporter
M1C60_RS27010	COG2755	lipolytic protein G-D-S-L family
M1C60_RS27015	COG1609	Transcriptional regulator
M1C60_RS27025	COG0460	homoserine dehydrogenase
M1C60_RS27035	COG2873	o-acetylhomoserine
M1C60_RS27045	COG1011	Hydrolase
M1C60_RS27050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1C60_RS27060	COG2197	response regulator
M1C60_RS27070	COG0351	phosphomethylpyrimidine kinase
M1C60_RS27075	COG3706	GGDEF domain
M1C60_RS27080	COG2879	small protein
M1C60_RS27085	COG1966	Carbon starvation protein
M1C60_RS27090	COG3279	Response regulator of the LytR AlgR family
M1C60_RS27095	COG0477	Major facilitator Superfamily
M1C60_RS27120	COG0840	transmembrane signaling receptor activity
M1C60_RS27130	COG1607	acyl-coa hydrolase
M1C60_RS27145	COG0488	(ABC) transporter
M1C60_RS27165	COG0463	Glycosyl transferase, family 2
M1C60_RS27170	COG1309	transcriptional regulator
M1C60_RS27175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1C60_RS27180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1C60_RS27180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M1C60_RS27185	COG0628	permease
M1C60_RS27200	COG3279	Response regulator of the LytR AlgR family
M1C60_RS27205	COG3275	phosphorelay sensor kinase activity
M1C60_RS27210	COG2814	Major facilitator Superfamily
M1C60_RS27215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1C60_RS27220	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M1C60_RS27225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1C60_RS27245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1C60_RS27250	COG1272	protein, Hemolysin III
M1C60_RS27270	COG0516	GMP reductase activity
M1C60_RS27275	COG1164	Oligoendopeptidase f
M1C60_RS27295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1C60_RS27300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M1C60_RS27305	COG4853	Protein conserved in bacteria
M1C60_RS27310	COG4863	YycH protein
M1C60_RS27315	COG5002	protein histidine kinase activity
M1C60_RS27320	COG0745	RESPONSE REGULATOR receiver
M1C60_RS27350	COG0305	Participates in initiation and elongation during chromosome replication
M1C60_RS27360	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M1C60_RS27365	COG4241	membrane
M1C60_RS27375	COG0629	single-stranded DNA binding
M1C60_RS27385	COG0012	GTP binding
M1C60_RS27390	COG4481	Protein conserved in bacteria
M1C60_RS27395	COG0668	transmembrane transport
M1C60_RS27405	COG1475	DNA binding
M1C60_RS27410	COG1192	Involved in chromosome partitioning
M1C60_RS27435	COG1847	R3H domain protein
M1C60_RS27440	COG0706	membrane insertase activity
M1C60_RS27450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M1C60_RS27555	COG4962	Type ii secretion system protein e
M1C60_RS27760	COG3344	reverse transcriptase
M1C60_RS27840	COG3344	reverse transcriptase
M1C60_RS27945	COG0457	Tetratricopeptide repeat
M1C60_RS27970	COG4974	Belongs to the 'phage' integrase family
M1C60_RS27980	COG3443	Belongs to the bacterial solute-binding protein 9 family
M1C60_RS28040	COG4974	Belongs to the 'phage' integrase family
M1C60_RS28050	COG2002	toxin-antitoxin pair type II binding
M1C60_RS28220	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M1C60_RS28225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1C60_RS28245	COG0671	phosphoesterase, PA-phosphatase related
M1C60_RS28250	COG4196	transglutaminase domain protein
M1C60_RS28270	COG2311	Membrane
M1C60_RS28460	COG0741	lytic transglycosylase activity
M1C60_RS28460	COG0791	NLP P60 protein
M1C60_RS28580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1C60_RS28590	COG4166	transmembrane transport
M1C60_RS28635	COG1280	lysine exporter protein (LysE YggA)
M1C60_RS28670	COG0681	Belongs to the peptidase S26 family
M1C60_RS28745	COG1309	transcriptional regulator
M1C60_RS28750	COG1683	Conserved Protein
M1C60_RS28795	COG1192	Involved in chromosome partitioning