locus-tag	class	description
FOC06_RS00010	COG0693	protein deglycase activity
FOC06_RS00010	COG0753	catalase activity
FOC06_RS00020	COG0531	amino acid
FOC06_RS00025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC06_RS00035	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS00040	COG1132	(ABC) transporter
FOC06_RS00050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC06_RS00055	COG0765	amino acid transport
FOC06_RS00060	COG1126	abc transporter atp-binding protein
FOC06_RS00075	COG0189	ligase activity
FOC06_RS00105	COG0028	Belongs to the TPP enzyme family
FOC06_RS00110	COG3527	Alpha-acetolactate decarboxylase
FOC06_RS00125	COG0561	phosphatase activity
FOC06_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC06_RS00155	COG0659	secondary active sulfate transmembrane transporter activity
FOC06_RS00175	COG0653	protein targeting
FOC06_RS00180	COG2244	polysaccharide biosynthetic process
FOC06_RS00190	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS00195	COG4196	transglutaminase domain protein
FOC06_RS00210	COG1696	Membrane protein involved in D-alanine export
FOC06_RS00225	COG1024	Enoyl-CoA hydratase
FOC06_RS00245	COG1363	Peptidase, m42
FOC06_RS00265	COG3938	Belongs to the proline racemase family
FOC06_RS00300	COG0601	transmembrane transport
FOC06_RS00305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC06_RS00315	COG4608	Belongs to the ABC transporter superfamily
FOC06_RS00320	COG0322	excinuclease ABC activity
FOC06_RS00350	COG0477	Major facilitator Superfamily
FOC06_RS00355	COG3290	protein histidine kinase activity
FOC06_RS00360	COG4565	transcriptional regulatory protein
FOC06_RS00365	COG3181	Tripartite tricarboxylate transporter family receptor
FOC06_RS00395	COG0789	Transcriptional regulator
FOC06_RS00395	COG4978	Transcriptional regulator
FOC06_RS00410	COG0305	Participates in initiation and elongation during chromosome replication
FOC06_RS00440	COG0477	Major facilitator Superfamily
FOC06_RS00485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC06_RS00485	COG3320	Male sterility
FOC06_RS00510	COG1183	phosphatidylcholine synthase activity
FOC06_RS00530	COG2376	Dihydroxyacetone kinase
FOC06_RS00540	COG2376	Dihydroxyacetone kinase
FOC06_RS00545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC06_RS00550	COG1959	2 iron, 2 sulfur cluster binding
FOC06_RS00580	COG2770	Histidine kinase
FOC06_RS00580	COG3437	response regulator, receiver
FOC06_RS00630	COG3237	CsbD-like
FOC06_RS00655	COG1191	sigma factor activity
FOC06_RS00665	COG2208	phosphoserine phosphatase activity
FOC06_RS00670	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC06_RS00675	COG2198	Histidine kinase
FOC06_RS00675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC06_RS00675	COG0784	Response regulator, receiver
FOC06_RS00675	COG2205	protein histidine kinase activity
FOC06_RS00695	COG0393	Putative heavy-metal-binding
FOC06_RS00725	COG0420	3'-5' exonuclease activity
FOC06_RS00750	COG1309	transcriptional regulator
FOC06_RS00755	COG2814	Major facilitator Superfamily
FOC06_RS00760	COG0346	lactoylglutathione lyase activity
FOC06_RS00765	COG0346	lactoylglutathione lyase activity
FOC06_RS00775	COG2267	carboxylic ester hydrolase activity
FOC06_RS00795	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC06_RS00800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC06_RS00810	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC06_RS00845	COG0477	Major facilitator Superfamily
FOC06_RS00850	COG0477	Major facilitator Superfamily
FOC06_RS00860	COG3973	AAA domain
FOC06_RS00885	COG4980	gas vesicle protein
FOC06_RS00890	COG0537	adenosine 5'-monophosphoramidase activity
FOC06_RS00895	COG1131	(ABC) transporter
FOC06_RS00900	COG4473	ABC transporter
FOC06_RS00915	COG1309	transcriptional regulator
FOC06_RS00920	COG3402	PFAM membrane-flanked domain
FOC06_RS00965	COG3402	PFAM membrane-flanked domain
FOC06_RS00970	COG3428	Bacterial PH domain
FOC06_RS00975	COG2329	Antibiotic biosynthesis monooxygenase
FOC06_RS00980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC06_RS00985	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC06_RS01030	COG1309	transcriptional regulator
FOC06_RS01035	COG1511	domain protein
FOC06_RS01060	COG1609	Transcriptional regulator
FOC06_RS01070	COG1234	tRNA 3'-trailer cleavage
FOC06_RS01075	COG0095	Lipoate-protein ligase
FOC06_RS01085	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS01115	COG3209	COG3209 Rhs family protein
FOC06_RS01150	COG1078	dGTPase activity
FOC06_RS01160	COG1595	DNA-templated transcription, initiation
FOC06_RS01165	COG2207	Transcriptional regulator
FOC06_RS01165	COG3708	Transcriptional regulator
FOC06_RS01175	COG2205	protein histidine kinase activity
FOC06_RS01180	COG0745	RESPONSE REGULATOR receiver
FOC06_RS01205	COG0501	Belongs to the peptidase M48B family
FOC06_RS01210	COG0840	transmembrane signaling receptor activity
FOC06_RS01215	COG0697	spore germination
FOC06_RS01230	COG0497	DNA recombination
FOC06_RS01235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC06_RS01240	COG2224	Isocitrate lyase
FOC06_RS01250	COG1278	Cold shock
FOC06_RS01265	COG4903	ComK protein
FOC06_RS01270	COG0398	Pfam SNARE associated Golgi protein
FOC06_RS01280	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC06_RS01285	COG1074	ATP-dependent DNA helicase activity
FOC06_RS01330	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC06_RS01355	COG0367	asparagine synthase
FOC06_RS01365	COG0753	catalase activity
FOC06_RS01390	COG2996	Protein conserved in bacteria
FOC06_RS01400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC06_RS01410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS01425	COG0561	phosphatase activity
FOC06_RS01435	COG0542	response to heat
FOC06_RS01445	COG2267	carboxylic ester hydrolase activity
FOC06_RS01460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC06_RS01465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC06_RS01470	COG5504	Zn-dependent protease
FOC06_RS01480	COG0180	Tryptophanyl-tRNA synthetase
FOC06_RS01490	COG4166	transmembrane transport
FOC06_RS01495	COG0601	transmembrane transport
FOC06_RS01500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC06_RS01505	COG0444	Belongs to the ABC transporter superfamily
FOC06_RS01510	COG4608	Belongs to the ABC transporter superfamily
FOC06_RS01515	COG0534	Mate efflux family protein
FOC06_RS01520	COG4166	transmembrane transport
FOC06_RS01530	COG1393	Belongs to the ArsC family
FOC06_RS01535	COG0861	Integral membrane protein TerC family
FOC06_RS01540	COG4862	establishment of competence for transformation
FOC06_RS01545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC06_RS01555	COG1164	Oligoendopeptidase f
FOC06_RS01565	COG2346	COG2346, Truncated hemoglobins
FOC06_RS01570	COG4116	CYTH
FOC06_RS01580	COG2357	RelA SpoT domain protein
FOC06_RS01585	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC06_RS01590	COG0564	pseudouridine synthase activity
FOC06_RS01610	COG1216	Glycosyl transferase, family 2
FOC06_RS01630	COG0463	Glycosyl transferase, family 2
FOC06_RS01630	COG0457	Tetratricopeptide repeat
FOC06_RS01650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC06_RS01665	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC06_RS01710	COG2153	protein acetylation
FOC06_RS01715	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC06_RS01720	COG2382	esterase
FOC06_RS01735	COG5492	domain, Protein
FOC06_RS01740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC06_RS01750	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC06_RS01750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC06_RS01785	COG1620	l-lactate permease
FOC06_RS01790	COG5634	Uncharacterized conserved protein (DUF2278)
FOC06_RS01845	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC06_RS01855	COG1476	TRANSCRIPTIONal
FOC06_RS01915	COG2226	methyltransferase
FOC06_RS01925	COG1686	Belongs to the peptidase S11 family
FOC06_RS01930	COG0681	Belongs to the peptidase S26 family
FOC06_RS01965	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS01970	COG3842	ATPase activity
FOC06_RS01975	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC06_RS01980	COG1177	transmembrane transport
FOC06_RS01985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC06_RS01995	COG2409	Drug exporters of the RND superfamily
FOC06_RS02005	COG0564	pseudouridine synthase activity
FOC06_RS02015	COG2340	Cysteine-rich secretory protein family
FOC06_RS02020	COG0247	lactate metabolic process
FOC06_RS02025	COG0277	FAD linked oxidase domain protein
FOC06_RS02030	COG3835	regulator
FOC06_RS02040	COG0745	RESPONSE REGULATOR receiver
FOC06_RS02045	COG5002	protein histidine kinase activity
FOC06_RS02050	COG2186	Transcriptional regulator
FOC06_RS02070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC06_RS02080	COG2116	formate transmembrane transporter activity
FOC06_RS02085	COG0861	Integral membrane protein TerC family
FOC06_RS02090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC06_RS02100	COG2030	dehydratase
FOC06_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS02125	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC06_RS02135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC06_RS02145	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC06_RS02160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC06_RS02175	COG1349	DNA-binding transcription factor activity
FOC06_RS02195	COG2861	carbohydrate metabolic process
FOC06_RS02205	COG3852	Histidine kinase
FOC06_RS02210	COG1846	Transcriptional regulator
FOC06_RS02220	COG2318	DinB family
FOC06_RS02225	COG5002	protein histidine kinase activity
FOC06_RS02235	COG0720	synthase
FOC06_RS02250	COG4873	Protein conserved in bacteria
FOC06_RS02275	COG1780	Probably involved in ribonucleotide reductase function
FOC06_RS02295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC06_RS02300	COG1725	Transcriptional regulator
FOC06_RS02305	COG1131	(ABC) transporter
FOC06_RS02315	COG1131	(ABC) transporter
FOC06_RS02320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC06_RS02335	COG1522	sequence-specific DNA binding
FOC06_RS02345	COG1335	isochorismatase
FOC06_RS02355	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC06_RS02360	COG2070	2-Nitropropane dioxygenase
FOC06_RS02365	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC06_RS02375	COG1696	Membrane protein involved in D-alanine export
FOC06_RS02395	COG0716	FMN binding
FOC06_RS02405	COG3173	Aminoglycoside phosphotransferase
FOC06_RS02420	COG0534	Mate efflux family protein
FOC06_RS02425	COG1968	undecaprenyl-diphosphatase activity
FOC06_RS02440	COG1846	Transcriptional regulator
FOC06_RS02450	COG1301	dicarboxylic acid transport
FOC06_RS02455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC06_RS02460	COG4709	membrane
FOC06_RS02465	COG3874	Sporulation protein YtfJ
FOC06_RS02490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC06_RS02495	COG0028	Belongs to the TPP enzyme family
FOC06_RS02500	COG0440	acetolactate synthase activity
FOC06_RS02505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC06_RS02515	COG0473	3-isopropylmalate dehydrogenase activity
FOC06_RS02540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC06_RS02575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC06_RS02590	COG1183	phosphatidylcholine synthase activity
FOC06_RS02595	COG1368	sulfuric ester hydrolase activity
FOC06_RS02605	COG0019	diaminopimelate decarboxylase activity
FOC06_RS02625	COG0529	Catalyzes the synthesis of activated sulfate
FOC06_RS02630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC06_RS02650	COG1648	precorrin-2 dehydrogenase activity
FOC06_RS02655	COG0733	neurotransmitter:sodium symporter activity
FOC06_RS02675	COG1757	Na H antiporter
FOC06_RS02690	COG4758	membrane
FOC06_RS02695	COG4585	Histidine kinase
FOC06_RS02700	COG2197	response regulator
FOC06_RS02710	COG1114	Component of the transport system for branched-chain amino acids
FOC06_RS02720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC06_RS02745	COG1017	nitric oxide dioxygenase activity
FOC06_RS02745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC06_RS02760	COG0730	response to heat
FOC06_RS02765	COG0306	phosphate transporter
FOC06_RS02770	COG1392	Phosphate transport regulator
FOC06_RS02775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC06_RS02795	COG1801	Protein of unknown function DUF72
FOC06_RS02805	COG0582	viral genome integration into host DNA
FOC06_RS02810	COG5002	protein histidine kinase activity
FOC06_RS02830	COG0392	lysyltransferase activity
FOC06_RS02830	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC06_RS02845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC06_RS02850	COG1686	Belongs to the peptidase S11 family
FOC06_RS02855	COG2715	membrane protein required for spore maturation
FOC06_RS02860	COG0700	Nucleoside recognition
FOC06_RS02865	COG1187	pseudouridine synthase activity
FOC06_RS02875	COG1333	cytochrome c biogenesis protein
FOC06_RS02880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC06_RS02885	COG0745	RESPONSE REGULATOR receiver
FOC06_RS02890	COG5002	protein histidine kinase activity
FOC06_RS02895	COG2096	Adenosyltransferase
FOC06_RS02910	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC06_RS02915	COG1141	Ferredoxin
FOC06_RS02920	COG4955	Helix-turn-helix domain
FOC06_RS02925	COG0514	ATP-dependent DNA helicase (RecQ)
FOC06_RS02930	COG1266	CAAX protease self-immunity
FOC06_RS02950	COG4862	establishment of competence for transformation
FOC06_RS02955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC06_RS02975	COG0492	ferredoxin-NADP+ reductase activity
FOC06_RS03050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC06_RS03065	COG0142	geranyltranstransferase activity
FOC06_RS03075	COG0142	geranyltranstransferase activity
FOC06_RS03080	COG0105	UTP biosynthetic process
FOC06_RS03095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC06_RS03100	COG0457	Tetratricopeptide repeat
FOC06_RS03120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC06_RS03130	COG4347	Protein of unknown function (DUF1405)
FOC06_RS03145	COG2738	Putative neutral zinc metallopeptidase
FOC06_RS03155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS03160	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC06_RS03175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC06_RS03180	COG0438	transferase activity, transferring glycosyl groups
FOC06_RS03215	COG1199	ATP-dependent helicase activity
FOC06_RS03215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC06_RS03235	COG3935	DnaD domain protein
FOC06_RS03240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC06_RS03250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC06_RS03250	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC06_RS03290	COG4474	Belongs to the UPF0398 family
FOC06_RS03305	COG0116	Belongs to the methyltransferase superfamily
FOC06_RS03315	COG1199	ATP-dependent helicase activity
FOC06_RS03320	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC06_RS03330	COG3173	Aminoglycoside phosphotransferase
FOC06_RS03335	COG0024	Methionine aminopeptidase
FOC06_RS03350	COG2233	PERMEase
FOC06_RS03355	COG2311	Membrane
FOC06_RS03360	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC06_RS03370	COG0456	acetyltransferase
FOC06_RS03420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC06_RS03445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC06_RS03460	COG1215	transferase activity, transferring glycosyl groups
FOC06_RS03480	COG0454	-acetyltransferase
FOC06_RS03500	COG0328	RNA-DNA hybrid ribonuclease activity
FOC06_RS03540	COG1280	lysine exporter protein (LysE YggA)
FOC06_RS03555	COG3162	membrane
FOC06_RS03560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC06_RS03565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC06_RS03575	COG0475	glutathione-regulated potassium exporter activity
FOC06_RS03585	COG4978	Transcriptional regulator
FOC06_RS03585	COG0789	Transcriptional regulator
FOC06_RS03595	COG2323	membrane
FOC06_RS03600	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC06_RS03655	COG1923	regulation of RNA biosynthetic process
FOC06_RS03665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC06_RS03670	COG1360	Flagellar Motor Protein
FOC06_RS03675	COG2201	protein-glutamate methylesterase activity
FOC06_RS03685	COG1776	CheC inhibitor of MCP methylation
FOC06_RS03685	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC06_RS03700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC06_RS03720	COG1256	bacterial-type flagellum assembly
FOC06_RS03745	COG1815	bacterial-type flagellum-dependent cell motility
FOC06_RS03750	COG1558	bacterial-type flagellum-dependent cell motility
FOC06_RS03755	COG1677	Flagellar hook-basal body complex protein FliE
FOC06_RS03765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC06_RS03775	COG1157	protein secretion by the type III secretion system
FOC06_RS03825	COG0463	Glycosyl transferase, family 2
FOC06_RS03860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC06_RS03865	COG0741	lytic transglycosylase activity
FOC06_RS03880	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC06_RS03880	COG1776	CheC inhibitor of MCP methylation
FOC06_RS03890	COG1338	Plays a role in the flagellum-specific transport system
FOC06_RS03895	COG1987	bacterial-type flagellum assembly
FOC06_RS03905	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC06_RS03910	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC06_RS03920	COG4786	Flagellar basal body rod
FOC06_RS03925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC06_RS03950	COG1309	transcriptional regulator
FOC06_RS03970	COG2329	Antibiotic biosynthesis monooxygenase
FOC06_RS04000	COG3842	ATPase activity
FOC06_RS04005	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC06_RS04010	COG1177	transmembrane transport
FOC06_RS04015	COG1234	tRNA 3'-trailer cleavage
FOC06_RS04045	COG1686	Belongs to the peptidase S11 family
FOC06_RS04055	COG0406	alpha-ribazole phosphatase activity
FOC06_RS04085	COG0367	asparagine synthase
FOC06_RS04115	COG1802	Transcriptional regulator
FOC06_RS04120	COG0697	spore germination
FOC06_RS04125	COG0523	cobalamin synthesis protein
FOC06_RS04130	COG0701	Predicted permease
FOC06_RS04140	COG1216	Glycosyl transferase, family 2
FOC06_RS04140	COG0438	transferase activity, transferring glycosyl groups
FOC06_RS04145	COG1757	Na H antiporter
FOC06_RS04150	COG0114	fumarate hydratase activity
FOC06_RS04175	COG3340	Belongs to the peptidase S51 family
FOC06_RS04195	COG0785	Cytochrome C biogenesis protein
FOC06_RS04225	COG2733	membrane
FOC06_RS04260	COG1131	(ABC) transporter
FOC06_RS04275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC06_RS04280	COG0528	UMP kinase activity
FOC06_RS04290	COG1027	Aspartate ammonia-lyase
FOC06_RS04295	COG0281	malic enzyme
FOC06_RS04300	COG4191	Histidine kinase
FOC06_RS04305	COG0784	Response regulator, receiver
FOC06_RS04310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC06_RS04360	COG1051	belongs to the nudix hydrolase family
FOC06_RS04365	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS04390	COG1966	Carbon starvation protein
FOC06_RS04405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC06_RS04425	COG2223	nitrite transmembrane transporter activity
FOC06_RS04430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC06_RS04445	COG2244	polysaccharide biosynthetic process
FOC06_RS04450	COG0733	neurotransmitter:sodium symporter activity
FOC06_RS04460	COG5566	PFAM Mor transcription activator
FOC06_RS04465	COG2323	membrane
FOC06_RS04480	COG2084	Dehydrogenase
FOC06_RS04495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC06_RS04505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC06_RS04510	COG0028	Belongs to the TPP enzyme family
FOC06_RS04515	COG0440	acetolactate synthase activity
FOC06_RS04520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC06_RS04530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC06_RS04555	COG2814	Major facilitator Superfamily
FOC06_RS04560	COG3384	dioxygenase
FOC06_RS04570	COG3279	Response regulator of the LytR AlgR family
FOC06_RS04575	COG0427	acetyl-CoA hydrolase
FOC06_RS04595	COG1073	alpha beta
FOC06_RS04630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS04650	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC06_RS04665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC06_RS04695	COG2390	Transcriptional regulator
FOC06_RS04705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS04710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC06_RS04725	COG4224	UPF0291 protein
FOC06_RS04745	COG0006	proline dipeptidase activity
FOC06_RS04750	COG2132	Multicopper oxidase
FOC06_RS04780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC06_RS04795	COG2372	response to copper ion
FOC06_RS04795	COG1276	copper resistance
FOC06_RS04800	COG4549	nuclear export factor GLE1
FOC06_RS04810	COG0697	spore germination
FOC06_RS04815	COG0583	DNA-binding transcription factor activity
FOC06_RS04820	COG1959	2 iron, 2 sulfur cluster binding
FOC06_RS04825	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC06_RS04830	COG0778	Nitroreductase
FOC06_RS04840	COG0628	permease
FOC06_RS04845	COG0039	L-malate dehydrogenase activity
FOC06_RS04850	COG1231	oxidoreductase activity
FOC06_RS04855	COG0523	cobalamin synthesis protein
FOC06_RS04870	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS04875	COG2030	dehydratase
FOC06_RS04880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC06_RS04890	COG0411	ABC transporter
FOC06_RS04910	COG0583	DNA-binding transcription factor activity
FOC06_RS04930	COG1846	Transcriptional regulator
FOC06_RS04940	COG1271	oxidase subunit
FOC06_RS04945	COG1294	oxidase, subunit
FOC06_RS04950	COG4988	ABC transporter
FOC06_RS04955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC06_RS04975	COG1686	Belongs to the peptidase S11 family
FOC06_RS04990	COG0791	NLP P60 protein
FOC06_RS04990	COG1388	LysM domain
FOC06_RS05005	COG0745	RESPONSE REGULATOR receiver
FOC06_RS05010	COG5002	protein histidine kinase activity
FOC06_RS05020	COG0300	oxidoreductase activity
FOC06_RS05035	COG0726	polysaccharide deacetylase
FOC06_RS05055	COG0460	homoserine dehydrogenase
FOC06_RS05080	COG1316	TRANSCRIPTIONal
FOC06_RS05090	COG0745	RESPONSE REGULATOR receiver
FOC06_RS05095	COG5002	protein histidine kinase activity
FOC06_RS05100	COG0726	polysaccharide deacetylase
FOC06_RS05110	COG1285	pathogenesis
FOC06_RS05115	COG1247	-acetyltransferase
FOC06_RS05125	COG4264	IucA IucC family
FOC06_RS05130	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS05145	COG1082	Xylose isomerase domain protein TIM barrel
FOC06_RS05160	COG1279	arginine transmembrane transporter activity
FOC06_RS05170	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC06_RS05210	COG2002	toxin-antitoxin pair type II binding
FOC06_RS05215	COG1404	Belongs to the peptidase S8 family
FOC06_RS05220	COG0640	Transcriptional regulator
FOC06_RS05225	COG0667	Aldo Keto reductase
FOC06_RS05230	COG2814	Major facilitator Superfamily
FOC06_RS05255	COG0840	transmembrane signaling receptor activity
FOC06_RS05270	COG3949	Membrane
FOC06_RS05275	COG0783	Belongs to the Dps family
FOC06_RS05290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC06_RS05300	COG1231	oxidoreductase activity
FOC06_RS05310	COG4989	oxidoreductase activity
FOC06_RS05315	COG0523	cobalamin synthesis protein
FOC06_RS05320	COG0456	acetyltransferase
FOC06_RS05370	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC06_RS05370	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC06_RS05375	COG0702	epimerase
FOC06_RS05385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC06_RS05395	COG4166	transmembrane transport
FOC06_RS05410	COG0406	alpha-ribazole phosphatase activity
FOC06_RS05420	COG5337	Spore coat protein CotH
FOC06_RS05425	COG1051	belongs to the nudix hydrolase family
FOC06_RS05430	COG0586	Pfam SNARE associated Golgi protein
FOC06_RS05435	COG2244	polysaccharide biosynthetic process
FOC06_RS05445	COG0701	Predicted permease
FOC06_RS05450	COG3689	TIGRFAM TIGR03943 family protein
FOC06_RS05455	COG1607	acyl-coa hydrolase
FOC06_RS05465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC06_RS05480	COG0702	epimerase
FOC06_RS05485	COG2839	Protein conserved in bacteria
FOC06_RS05490	COG1253	flavin adenine dinucleotide binding
FOC06_RS05505	COG1114	Component of the transport system for branched-chain amino acids
FOC06_RS05510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC06_RS05530	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS05540	COG1876	peptidase activity
FOC06_RS05550	COG0154	amidase activity
FOC06_RS05555	COG2211	Major facilitator Superfamily
FOC06_RS05575	COG0561	phosphatase activity
FOC06_RS05585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC06_RS05605	COG1819	glycosyl
FOC06_RS05610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS05615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS05640	COG0456	acetyltransferase
FOC06_RS05690	COG3874	Sporulation protein YtfJ
FOC06_RS05715	COG2226	methyltransferase
FOC06_RS05740	COG0346	lactoylglutathione lyase activity
FOC06_RS05750	COG0604	alcohol dehydrogenase
FOC06_RS05755	COG1595	DNA-templated transcription, initiation
FOC06_RS05780	COG0386	Belongs to the glutathione peroxidase family
FOC06_RS05785	COG1305	Transglutaminase-like
FOC06_RS05790	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC06_RS05795	COG0714	Associated with various cellular activities
FOC06_RS05810	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC06_RS05815	COG1140	nitrate reductase beta subunit
FOC06_RS05820	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC06_RS05825	COG2181	nitrate reductase activity
FOC06_RS05845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC06_RS05850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC06_RS05855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC06_RS05860	COG0303	'Molybdopterin
FOC06_RS05865	COG0314	molybdopterin synthase activity
FOC06_RS05875	COG2223	nitrite transmembrane transporter activity
FOC06_RS05890	COG1648	precorrin-2 dehydrogenase activity
FOC06_RS05900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC06_RS05900	COG1587	Uroporphyrinogen-III synthase
FOC06_RS05905	COG2146	nitrite reductase [NAD(P)H] activity
FOC06_RS05910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC06_RS05915	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC06_RS05950	COG2359	stage V sporulation protein S
FOC06_RS05965	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS05980	COG1418	mRNA catabolic process
FOC06_RS05985	COG0488	(ABC) transporter
FOC06_RS06000	COG0629	single-stranded DNA binding
FOC06_RS06015	COG1413	lyase activity
FOC06_RS06030	COG2136	Putative SAM-dependent methyltransferase
FOC06_RS06030	COG2521	methyltransferase
FOC06_RS06035	COG0018	arginyl-trna synthetase
FOC06_RS06060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC06_RS06080	COG0017	Asparaginyl-tRNA synthetase
FOC06_RS06100	COG1674	ftsk spoiiie
FOC06_RS06170	COG1929	Belongs to the glycerate kinase type-1 family
FOC06_RS06175	COG0471	metal ion transport
FOC06_RS06180	COG0745	RESPONSE REGULATOR receiver
FOC06_RS06185	COG3850	Histidine kinase
FOC06_RS06185	COG5002	protein histidine kinase activity
FOC06_RS06200	COG0733	neurotransmitter:sodium symporter activity
FOC06_RS06225	COG2610	gluconate transmembrane transporter activity
FOC06_RS06230	COG1454	alcohol dehydrogenase
FOC06_RS06235	COG1794	racemase activity, acting on amino acids and derivatives
FOC06_RS06245	COG0456	acetyltransferase
FOC06_RS06260	COG1131	(ABC) transporter
FOC06_RS06275	COG0546	phosphoglycolate phosphatase activity
FOC06_RS06295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC06_RS06310	COG0768	penicillin binding
FOC06_RS06315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC06_RS06320	COG0204	Acyl-transferase
FOC06_RS06325	COG1272	protein, Hemolysin III
FOC06_RS06335	COG0805	protein transport
FOC06_RS06345	COG1307	EDD domain protein, DegV family
FOC06_RS06350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC06_RS06355	COG1999	signal sequence binding
FOC06_RS06360	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC06_RS06365	COG0367	asparagine synthase
FOC06_RS06380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS06385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC06_RS06410	COG1051	belongs to the nudix hydrolase family
FOC06_RS06420	COG0668	transmembrane transport
FOC06_RS06425	COG4585	Histidine kinase
FOC06_RS06425	COG2203	Gaf domain
FOC06_RS06430	COG2197	response regulator
FOC06_RS06440	COG1064	alcohol dehydrogenase
FOC06_RS06465	COG1070	Carbohydrate kinase
FOC06_RS06500	COG0517	IMP dehydrogenase activity
FOC06_RS06500	COG1125	glycine betaine transport
FOC06_RS06505	COG1174	glycine betaine transport
FOC06_RS06540	COG1253	flavin adenine dinucleotide binding
FOC06_RS06545	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS06550	COG5506	Protein of unknown function (DUF1694)
FOC06_RS06565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC06_RS06570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC06_RS06575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC06_RS06580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC06_RS06585	COG0456	acetyltransferase
FOC06_RS06590	COG3829	transcription factor binding
FOC06_RS06595	COG1509	lysine 2,3-aminomutase activity
FOC06_RS06635	COG4326	sporulation control protein
FOC06_RS06640	COG0671	phosphoesterase, PA-phosphatase related
FOC06_RS06645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC06_RS06650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC06_RS06680	COG1715	Restriction endonuclease
FOC06_RS06680	COG1787	Restriction endonuclease
FOC06_RS06770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC06_RS06810	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC06_RS06810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC06_RS06815	COG2814	Major facilitator Superfamily
FOC06_RS06820	COG4841	protein insertion into membrane
FOC06_RS06825	COG0372	Belongs to the citrate synthase family
FOC06_RS06830	COG2079	MmgE PrpD family protein
FOC06_RS06835	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC06_RS06840	COG1960	acyl-CoA dehydrogenase activity
FOC06_RS06845	COG2084	Dehydrogenase
FOC06_RS06850	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS06855	COG1280	lysine exporter protein (LysE YggA)
FOC06_RS06860	COG1024	Enoyl-CoA hydratase
FOC06_RS06875	COG0420	3'-5' exonuclease activity
FOC06_RS06880	COG0419	ATPase involved in DNA repair
FOC06_RS06900	COG2223	nitrite transmembrane transporter activity
FOC06_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS06910	COG1169	isochorismate synthase
FOC06_RS06915	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC06_RS06920	COG3433	isochorismatase activity
FOC06_RS06920	COG1535	isochorismatase
FOC06_RS06925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC06_RS06930	COG3251	PFAM MbtH domain protein
FOC06_RS06935	COG2814	Major facilitator Superfamily
FOC06_RS06950	COG0776	regulation of translation
FOC06_RS06960	COG2318	DinB family
FOC06_RS06970	COG1115	amino acid carrier protein
FOC06_RS06985	COG2329	Antibiotic biosynthesis monooxygenase
FOC06_RS06990	COG1187	pseudouridine synthase activity
FOC06_RS06995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC06_RS07010	COG0596	Alpha beta hydrolase
FOC06_RS07015	COG2814	Major facilitator Superfamily
FOC06_RS07035	COG2226	methyltransferase
FOC06_RS07080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS07115	COG1247	-acetyltransferase
FOC06_RS07155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS07165	COG1278	Cold shock
FOC06_RS07180	COG0010	Belongs to the arginase family
FOC06_RS07185	COG0561	phosphatase activity
FOC06_RS07220	COG0583	DNA-binding transcription factor activity
FOC06_RS07225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC06_RS07240	COG0583	DNA-binding transcription factor activity
FOC06_RS07245	COG2258	MOSC domain
FOC06_RS07260	COG1132	(ABC) transporter
FOC06_RS07265	COG1132	(ABC) transporter
FOC06_RS07285	COG1396	sequence-specific DNA binding
FOC06_RS07315	COG1595	DNA-templated transcription, initiation
FOC06_RS07365	COG2971	BadF BadG BcrA BcrD
FOC06_RS07370	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC06_RS07375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC06_RS07395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS07425	COG1309	transcriptional regulator
FOC06_RS07440	COG0577	efflux transmembrane transporter activity
FOC06_RS07440	COG1136	(ABC) transporter
FOC06_RS07445	COG0500	methyltransferase
FOC06_RS07445	COG3615	Tellurite resistance protein tehB
FOC06_RS07455	COG2226	methyltransferase
FOC06_RS07460	COG3961	Belongs to the TPP enzyme family
FOC06_RS07465	COG1846	Transcriptional regulator
FOC06_RS07495	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC06_RS07510	COG1595	DNA-templated transcription, initiation
FOC06_RS07520	COG0768	penicillin binding
FOC06_RS07530	COG2367	Beta-lactamase
FOC06_RS07535	COG0671	phosphoesterase, PA-phosphatase related
FOC06_RS07540	COG1609	Transcriptional regulator
FOC06_RS07545	COG2814	Major facilitator Superfamily
FOC06_RS07550	COG0673	inositol 2-dehydrogenase activity
FOC06_RS07560	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS07580	COG3718	enzyme involved in inositol metabolism
FOC06_RS07605	COG0457	Tetratricopeptide repeat
FOC06_RS07610	COG1476	TRANSCRIPTIONal
FOC06_RS07625	COG1876	peptidase activity
FOC06_RS07645	COG1309	transcriptional regulator
FOC06_RS07665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS07680	COG1252	NADH dehydrogenase
FOC06_RS07685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC06_RS07700	COG1131	(ABC) transporter
FOC06_RS07710	COG1309	transcriptional regulator
FOC06_RS07725	COG1960	acyl-CoA dehydrogenase activity
FOC06_RS07730	COG0439	Biotin carboxylase
FOC06_RS07735	COG0511	ligase activity, forming carbon-carbon bonds
FOC06_RS07740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC06_RS07745	COG1024	Enoyl-CoA hydratase
FOC06_RS07750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC06_RS07755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC06_RS07765	COG1247	-acetyltransferase
FOC06_RS07770	COG0572	uridine kinase
FOC06_RS07780	COG2318	DinB family
FOC06_RS07785	COG1686	Belongs to the peptidase S11 family
FOC06_RS07810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC06_RS07850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC06_RS07850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC06_RS07865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC06_RS07875	COG2814	Major facilitator Superfamily
FOC06_RS07890	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC06_RS07910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS07925	COG1063	alcohol dehydrogenase
FOC06_RS07950	COG3773	Cell wall hydrolase
FOC06_RS07960	COG0745	RESPONSE REGULATOR receiver
FOC06_RS07990	COG1136	(ABC) transporter
FOC06_RS08015	COG0460	homoserine dehydrogenase
FOC06_RS08020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS08030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC06_RS08095	COG2124	cytochrome p450
FOC06_RS08130	COG0561	phosphatase activity
FOC06_RS08140	COG5002	protein histidine kinase activity
FOC06_RS08150	COG1819	glycosyl
FOC06_RS08155	COG1794	racemase activity, acting on amino acids and derivatives
FOC06_RS08165	COG1122	ATPase activity
FOC06_RS08180	COG2205	protein histidine kinase activity
FOC06_RS08195	COG0604	alcohol dehydrogenase
FOC06_RS08210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC06_RS08245	COG0693	protein deglycase activity
FOC06_RS08275	COG2814	Major facilitator Superfamily
FOC06_RS08290	COG0584	glycerophosphoryl diester phosphodiesterase
FOC06_RS08310	COG0697	spore germination
FOC06_RS08340	COG2223	nitrite transmembrane transporter activity
FOC06_RS08355	COG2816	NAD+ diphosphatase activity
FOC06_RS08360	COG0592	DNA-directed DNA polymerase activity
FOC06_RS08365	COG1051	belongs to the nudix hydrolase family
FOC06_RS08400	COG3878	Protein conserved in bacteria
FOC06_RS08450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC06_RS08465	COG0322	excinuclease ABC activity
FOC06_RS08505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC06_RS08530	COG1011	Hydrolase
FOC06_RS08550	COG0076	glutamate decarboxylase activity
FOC06_RS08565	COG1523	belongs to the glycosyl hydrolase 13 family
FOC06_RS08570	COG3227	Zinc metalloprotease (Elastase)
FOC06_RS08590	COG0201	protein transport
FOC06_RS08600	COG0697	spore germination
FOC06_RS08605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS08635	COG4129	membrane
FOC06_RS08640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS08655	COG2959	enzyme of heme biosynthesis
FOC06_RS08660	COG3409	Peptidoglycan-binding domain 1 protein
FOC06_RS08660	COG3773	Cell wall hydrolase
FOC06_RS08675	COG3483	tryptophan 2,3-dioxygenase activity
FOC06_RS08680	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC06_RS08685	COG3844	kynureninase activity
FOC06_RS08690	COG1309	transcriptional regulator
FOC06_RS08720	COG3284	Transcriptional regulator
FOC06_RS08735	COG1349	DNA-binding transcription factor activity
FOC06_RS08755	COG1959	2 iron, 2 sulfur cluster binding
FOC06_RS08770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC06_RS08775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC06_RS08780	COG0022	dehydrogenase e1 component
FOC06_RS08785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC06_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS08800	COG0456	acetyltransferase
FOC06_RS08800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC06_RS08830	COG4176	ABC-type proline glycine betaine transport system permease component
FOC06_RS08835	COG4175	Glycine betaine
FOC06_RS08835	COG0517	IMP dehydrogenase activity
FOC06_RS08845	COG0740	serine-type endopeptidase activity
FOC06_RS08860	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC06_RS08865	COG2153	protein acetylation
FOC06_RS08870	COG3397	chitin binding
FOC06_RS08885	COG2205	protein histidine kinase activity
FOC06_RS08905	COG2333	competence protein COMEC
FOC06_RS08905	COG0658	competence protein
FOC06_RS08955	COG3973	AAA domain
FOC06_RS08970	COG2105	PFAM AIG2 family protein
FOC06_RS08975	COG0514	ATP-dependent DNA helicase (RecQ)
FOC06_RS08995	COG4637	Psort location Cytoplasmic, score
FOC06_RS09020	COG3397	chitin binding
FOC06_RS09035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC06_RS09040	COG1115	amino acid carrier protein
FOC06_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS09050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC06_RS09060	COG3938	Belongs to the proline racemase family
FOC06_RS09065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC06_RS09105	COG0586	Pfam SNARE associated Golgi protein
FOC06_RS09120	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC06_RS09125	COG0519	Catalyzes the synthesis of GMP from XMP
FOC06_RS09130	COG4166	transmembrane transport
FOC06_RS09140	COG4948	Mandelate Racemase Muconate Lactonizing
FOC06_RS09185	COG2936	dipeptidyl-peptidase activity
FOC06_RS09190	COG5002	protein histidine kinase activity
FOC06_RS09230	COG1164	Oligoendopeptidase f
FOC06_RS09245	COG1307	EDD domain protein, DegV family
FOC06_RS09265	COG2814	Major facilitator Superfamily
FOC06_RS09275	COG1664	Polymer-forming cytoskeletal
FOC06_RS09280	COG0789	Transcriptional regulator
FOC06_RS09285	COG4533	DNA binding
FOC06_RS09290	COG2814	Major facilitator Superfamily
FOC06_RS09290	COG0477	Major facilitator Superfamily
FOC06_RS09310	COG2261	transglycosylase associated protein
FOC06_RS09325	COG2226	methyltransferase
FOC06_RS09360	COG0436	Aminotransferase
FOC06_RS09365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC06_RS09370	COG5146	pantothenate kinase activity
FOC06_RS09430	COG0628	permease
FOC06_RS09440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC06_RS09445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC06_RS09450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC06_RS09455	COG1116	anion transmembrane transporter activity
FOC06_RS09495	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC06_RS09520	COG0697	spore germination
FOC06_RS09525	COG2318	DinB family
FOC06_RS09545	COG4912	Dna alkylation repair
FOC06_RS09555	COG0726	polysaccharide deacetylase
FOC06_RS09565	COG0861	Integral membrane protein TerC family
FOC06_RS09570	COG1368	sulfuric ester hydrolase activity
FOC06_RS09575	COG0488	(ABC) transporter
FOC06_RS09585	COG2409	Drug exporters of the RND superfamily
FOC06_RS09585	COG1033	growth of symbiont in host cell
FOC06_RS09590	COG2409	Drug exporters of the RND superfamily
FOC06_RS09590	COG1033	growth of symbiont in host cell
FOC06_RS09595	COG1033	growth of symbiont in host cell
FOC06_RS09595	COG2409	Drug exporters of the RND superfamily
FOC06_RS09600	COG1309	transcriptional regulator
FOC06_RS09615	COG0287	Prephenate dehydrogenase
FOC06_RS09620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC06_RS09625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC06_RS09630	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC06_RS09630	COG1605	Chorismate mutase
FOC06_RS09665	COG1388	LysM domain
FOC06_RS09665	COG3584	3D domain protein
FOC06_RS09675	COG1595	DNA-templated transcription, initiation
FOC06_RS09700	COG1879	ABC-type sugar transport system periplasmic component
FOC06_RS09710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC06_RS09720	COG2390	Transcriptional regulator
FOC06_RS09755	COG2329	Antibiotic biosynthesis monooxygenase
FOC06_RS09775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS09785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC06_RS09790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC06_RS09795	COG4187	Peptidase family M20/M25/M40
FOC06_RS09800	COG1414	Transcriptional regulator
FOC06_RS09805	COG0833	amino acid
FOC06_RS09810	COG1690	Belongs to the RtcB family
FOC06_RS09815	COG3239	Fatty acid desaturase
FOC06_RS09820	COG1785	Belongs to the alkaline phosphatase family
FOC06_RS09830	COG3655	Transcriptional regulator
FOC06_RS09845	COG4377	Putative membrane peptidase family (DUF2324)
FOC06_RS09855	COG3279	Response regulator of the LytR AlgR family
FOC06_RS09865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS09870	COG0346	lactoylglutathione lyase activity
FOC06_RS09890	COG0714	Associated with various cellular activities
FOC06_RS09915	COG0463	Glycosyl transferase, family 2
FOC06_RS09940	COG0463	Glycosyl transferase, family 2
FOC06_RS09950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC06_RS09955	COG0753	catalase activity
FOC06_RS09965	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC06_RS09990	COG0714	Associated with various cellular activities
FOC06_RS10000	COG0778	Nitroreductase
FOC06_RS10005	COG1846	Transcriptional regulator
FOC06_RS10040	COG1725	Transcriptional regulator
FOC06_RS10050	COG1136	(ABC) transporter
FOC06_RS10050	COG0577	efflux transmembrane transporter activity
FOC06_RS10075	COG2207	Transcriptional regulator
FOC06_RS10080	COG0456	acetyltransferase
FOC06_RS10100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS10120	COG0642	Histidine kinase
FOC06_RS10125	COG0745	RESPONSE REGULATOR receiver
FOC06_RS10130	COG0596	Alpha beta hydrolase
FOC06_RS10160	COG0730	response to heat
FOC06_RS10170	COG0833	amino acid
FOC06_RS10180	COG4335	DNA alkylation repair
FOC06_RS10225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC06_RS10255	COG1984	allophanate hydrolase subunit 2
FOC06_RS10260	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC06_RS10265	COG1414	Transcriptional regulator
FOC06_RS10280	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS10285	COG0640	Transcriptional regulator
FOC06_RS10295	COG1960	acyl-CoA dehydrogenase activity
FOC06_RS10325	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC06_RS10340	COG0574	Belongs to the PEP-utilizing enzyme family
FOC06_RS10340	COG3848	Pyruvate phosphate dikinase
FOC06_RS10345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS10360	COG5577	PFAM Coat F domain
FOC06_RS10365	COG3403	YqcI/YcgG family
FOC06_RS10370	COG1280	lysine exporter protein (LysE YggA)
FOC06_RS10400	COG1063	alcohol dehydrogenase
FOC06_RS10415	COG1027	Aspartate ammonia-lyase
FOC06_RS10420	COG0252	asparaginase activity
FOC06_RS10425	COG1396	sequence-specific DNA binding
FOC06_RS10435	COG0322	excinuclease ABC activity
FOC06_RS10440	COG0531	amino acid
FOC06_RS10445	COG1114	Component of the transport system for branched-chain amino acids
FOC06_RS10450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC06_RS10460	COG0281	malic enzyme
FOC06_RS10485	COG0784	Response regulator, receiver
FOC06_RS10495	COG2066	Belongs to the glutaminase family
FOC06_RS10530	COG0737	Belongs to the 5'-nucleotidase family
FOC06_RS10535	COG0753	catalase activity
FOC06_RS10540	COG2267	carboxylic ester hydrolase activity
FOC06_RS10545	COG1335	isochorismatase
FOC06_RS10565	COG0583	DNA-binding transcription factor activity
FOC06_RS10570	COG1846	Transcriptional regulator
FOC06_RS10610	COG0415	Belongs to the DNA photolyase family
FOC06_RS10615	COG0288	reversible hydration of carbon dioxide
FOC06_RS10625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC06_RS10630	COG5609	conserved protein (DUF2294)
FOC06_RS10645	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC06_RS10650	COG2267	carboxylic ester hydrolase activity
FOC06_RS10655	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC06_RS10660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC06_RS10665	COG1121	(ABC) transporter
FOC06_RS10695	COG0798	PFAM Bile acid sodium symporter
FOC06_RS10700	COG0346	lactoylglutathione lyase activity
FOC06_RS10705	COG0640	Transcriptional regulator
FOC06_RS10720	COG0443	Heat shock 70 kDa protein
FOC06_RS10735	COG1522	sequence-specific DNA binding
FOC06_RS10750	COG0346	lactoylglutathione lyase activity
FOC06_RS10775	COG2169	Transcriptional regulator
FOC06_RS10815	COG2814	Major facilitator Superfamily
FOC06_RS10840	COG0745	RESPONSE REGULATOR receiver
FOC06_RS10845	COG5002	protein histidine kinase activity
FOC06_RS10845	COG3850	Histidine kinase
FOC06_RS10870	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC06_RS10890	COG1476	TRANSCRIPTIONal
FOC06_RS10905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS10910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC06_RS10920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC06_RS10925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC06_RS10940	COG1136	(ABC) transporter
FOC06_RS10945	COG0577	efflux transmembrane transporter activity
FOC06_RS10960	COG3850	Histidine kinase
FOC06_RS10960	COG5002	protein histidine kinase activity
FOC06_RS10970	COG2364	Membrane
FOC06_RS10975	COG1846	Transcriptional regulator
FOC06_RS10985	COG2808	Putative FMN-binding domain
FOC06_RS10990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS10995	COG2271	Major facilitator Superfamily
FOC06_RS11000	COG1556	Lactate utilization protein
FOC06_RS11005	COG1139	Iron-sulfur cluster binding protein
FOC06_RS11015	COG0583	DNA-binding transcription factor activity
FOC06_RS11025	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC06_RS11045	COG0738	Major facilitator superfamily
FOC06_RS11050	COG0673	inositol 2-dehydrogenase activity
FOC06_RS11055	COG0561	phosphatase activity
FOC06_RS11065	COG1609	Transcriptional regulator
FOC06_RS11070	COG0457	Tetratricopeptide repeat
FOC06_RS11085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC06_RS11115	COG0534	Mate efflux family protein
FOC06_RS11135	COG2814	Major facilitator Superfamily
FOC06_RS11140	COG1309	transcriptional regulator
FOC06_RS11155	COG0814	amino acid
FOC06_RS11160	COG1760	l-serine dehydratase
FOC06_RS11165	COG1760	l-serine dehydratase
FOC06_RS11175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC06_RS11180	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC06_RS11190	COG1335	isochorismatase
FOC06_RS11195	COG1522	sequence-specific DNA binding
FOC06_RS11200	COG0531	amino acid
FOC06_RS11215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC06_RS11235	COG1595	DNA-templated transcription, initiation
FOC06_RS11250	COG0662	Cupin 2, conserved barrel domain protein
FOC06_RS11255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS11255	COG2207	Transcriptional regulator
FOC06_RS11305	COG0477	Major facilitator Superfamily
FOC06_RS11315	COG1846	Transcriptional regulator
FOC06_RS11320	COG2814	Major facilitator Superfamily
FOC06_RS11335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC06_RS11340	COG1131	(ABC) transporter
FOC06_RS11360	COG2076	Multidrug Resistance protein
FOC06_RS11365	COG1309	transcriptional regulator
FOC06_RS11375	COG2031	fatty acid transporter
FOC06_RS11385	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC06_RS11415	COG1122	ATPase activity
FOC06_RS11420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC06_RS11435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC06_RS11440	COG1288	antiporter activity
FOC06_RS11445	COG2356	endonuclease I
FOC06_RS11460	COG3620	sequence-specific DNA binding
FOC06_RS11465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC06_RS11470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC06_RS11475	COG0124	histidyl-tRNA synthetase
FOC06_RS11490	COG1733	regulation of RNA biosynthetic process
FOC06_RS11495	COG0778	Nitroreductase
FOC06_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS11525	COG1131	(ABC) transporter
FOC06_RS11550	COG1011	Hydrolase
FOC06_RS11585	COG0346	lactoylglutathione lyase activity
FOC06_RS11590	COG1940	carbohydrate kinase activity
FOC06_RS11595	COG0738	Major facilitator superfamily
FOC06_RS11600	COG0110	maltose O-acetyltransferase activity
FOC06_RS11610	COG1136	(ABC) transporter
FOC06_RS11615	COG0180	Tryptophanyl-tRNA synthetase
FOC06_RS11620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC06_RS11625	COG0628	permease
FOC06_RS11640	COG2226	methyltransferase
FOC06_RS11650	COG0477	Major facilitator Superfamily
FOC06_RS11680	COG1253	flavin adenine dinucleotide binding
FOC06_RS11685	COG0789	Transcriptional regulator
FOC06_RS11690	COG0697	spore germination
FOC06_RS11695	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC06_RS11700	COG3813	Protein conserved in bacteria
FOC06_RS11705	COG2706	6-phosphogluconolactonase activity
FOC06_RS11710	COG1070	Carbohydrate kinase
FOC06_RS11720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC06_RS11725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC06_RS11735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC06_RS11740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC06_RS11745	COG0604	alcohol dehydrogenase
FOC06_RS11750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC06_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS11790	COG0656	L-ascorbic acid biosynthetic process
FOC06_RS11795	COG2814	Major facilitator Superfamily
FOC06_RS11810	COG0346	lactoylglutathione lyase activity
FOC06_RS11815	COG0814	amino acid
FOC06_RS11840	COG1393	Belongs to the ArsC family
FOC06_RS11845	COG1733	regulation of RNA biosynthetic process
FOC06_RS11850	COG2188	Transcriptional regulator
FOC06_RS11860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC06_RS11865	COG1733	regulation of RNA biosynthetic process
FOC06_RS11870	COG1733	regulation of RNA biosynthetic process
FOC06_RS11885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS11905	COG0384	phenazine biosynthesis protein PhzF
FOC06_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS11925	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS11935	COG1733	regulation of RNA biosynthetic process
FOC06_RS11970	COG1191	sigma factor activity
FOC06_RS11985	COG1309	transcriptional regulator
FOC06_RS12005	COG3152	Membrane
FOC06_RS12030	COG1151	hydroxylamine reductase activity
FOC06_RS12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS12045	COG3409	Peptidoglycan-binding domain 1 protein
FOC06_RS12045	COG3757	hydrolase, family 25
FOC06_RS12080	COG2072	flavoprotein involved in K transport
FOC06_RS12120	COG1113	amino acid transport
FOC06_RS12125	COG2814	Major facilitator Superfamily
FOC06_RS12155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC06_RS12160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC06_RS12180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS12185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS12190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS12195	COG3739	integral membrane protein
FOC06_RS12200	COG0384	phenazine biosynthesis protein PhzF
FOC06_RS12230	COG0583	DNA-binding transcription factor activity
FOC06_RS12250	COG1193	negative regulation of DNA recombination
FOC06_RS12270	COG1164	Oligoendopeptidase f
FOC06_RS12275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC06_RS12305	COG0584	glycerophosphoryl diester phosphodiesterase
FOC06_RS12330	COG0640	Transcriptional regulator
FOC06_RS12335	COG0604	alcohol dehydrogenase
FOC06_RS12355	COG2808	Putative FMN-binding domain
FOC06_RS12360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC06_RS12370	COG0385	Bile acid
FOC06_RS12375	COG0277	FAD linked oxidase domain protein
FOC06_RS12405	COG1216	Glycosyl transferase, family 2
FOC06_RS12410	COG1024	Enoyl-CoA hydratase
FOC06_RS12420	COG1285	pathogenesis
FOC06_RS12435	COG2514	catechol 2,3-dioxygenase activity
FOC06_RS12440	COG2720	vancomycin resistance protein
FOC06_RS12465	COG1278	Cold shock
FOC06_RS12475	COG0716	FMN binding
FOC06_RS12505	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS12515	COG0165	Argininosuccinate lyase
FOC06_RS12530	COG4145	pantothenate transmembrane transporter activity
FOC06_RS12540	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS12555	COG1657	PFAM Prenyltransferase squalene oxidase
FOC06_RS12560	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC06_RS12565	COG2962	Rard protein
FOC06_RS12570	COG3326	Membrane
FOC06_RS12585	COG0489	protein tyrosine kinase activity
FOC06_RS12595	COG0314	molybdopterin synthase activity
FOC06_RS12600	COG0303	'Molybdopterin
FOC06_RS12605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC06_RS12610	COG2116	formate transmembrane transporter activity
FOC06_RS12620	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC06_RS12625	COG5609	conserved protein (DUF2294)
FOC06_RS12630	COG2427	Protein of unknown function (DUF1641)
FOC06_RS12635	COG3383	formate dehydrogenase (NAD+) activity
FOC06_RS12640	COG0697	spore germination
FOC06_RS12680	COG2226	methyltransferase
FOC06_RS12685	COG4166	transmembrane transport
FOC06_RS12690	COG4166	transmembrane transport
FOC06_RS12695	COG4166	transmembrane transport
FOC06_RS12705	COG1316	TRANSCRIPTIONal
FOC06_RS12715	COG1595	DNA-templated transcription, initiation
FOC06_RS12730	COG1131	(ABC) transporter
FOC06_RS12740	COG0673	inositol 2-dehydrogenase activity
FOC06_RS12745	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC06_RS12750	COG0187	DNA topoisomerase II activity
FOC06_RS12755	COG1832	CoA-binding protein
FOC06_RS12760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC06_RS12765	COG0745	RESPONSE REGULATOR receiver
FOC06_RS12780	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC06_RS12785	COG4841	protein insertion into membrane
FOC06_RS12790	COG0824	Thioesterase
FOC06_RS12820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC06_RS12830	COG2274	protein secretion by the type I secretion system
FOC06_RS12835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC06_RS12845	COG0726	polysaccharide deacetylase
FOC06_RS12875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC06_RS12890	COG0183	Belongs to the thiolase family
FOC06_RS12895	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS12900	COG1268	BioY protein
FOC06_RS12905	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS12955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS12965	COG5002	protein histidine kinase activity
FOC06_RS12970	COG0400	carboxylic ester hydrolase activity
FOC06_RS12975	COG0346	lactoylglutathione lyase activity
FOC06_RS12980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC06_RS12985	COG0069	glutamate synthase activity
FOC06_RS12990	COG1902	pentaerythritol trinitrate reductase activity
FOC06_RS12995	COG1329	Transcriptional regulator
FOC06_RS13000	COG0010	Belongs to the arginase family
FOC06_RS13025	COG2226	methyltransferase
FOC06_RS13080	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC06_RS13085	COG0785	Cytochrome C biogenesis protein
FOC06_RS13095	COG0583	DNA-binding transcription factor activity
FOC06_RS13100	COG1380	Effector of murein hydrolase LrgA
FOC06_RS13105	COG1346	cytolysis
FOC06_RS13130	COG3409	Peptidoglycan-binding domain 1 protein
FOC06_RS13130	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS13145	COG1132	(ABC) transporter
FOC06_RS13150	COG1132	(ABC) transporter
FOC06_RS13180	COG3639	organic phosphonate transmembrane transporter activity
FOC06_RS13185	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC06_RS13205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC06_RS13225	COG1695	Transcriptional regulator
FOC06_RS13255	COG1388	LysM domain
FOC06_RS13255	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS13255	COG3409	Peptidoglycan-binding domain 1 protein
FOC06_RS13260	COG4824	toxin secretion phage lysis holin
FOC06_RS13405	COG1595	DNA-templated transcription, initiation
FOC06_RS13445	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC06_RS13525	COG1396	sequence-specific DNA binding
FOC06_RS13545	COG0174	glutamine synthetase
FOC06_RS13550	COG0789	Transcriptional regulator
FOC06_RS13555	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC06_RS13565	COG2860	membrane
FOC06_RS13575	COG0464	growth
FOC06_RS13605	COG1388	LysM domain
FOC06_RS13605	COG3584	3D domain protein
FOC06_RS13610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC06_RS13610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC06_RS13610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC06_RS13615	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC06_RS13620	COG1349	DNA-binding transcription factor activity
FOC06_RS13630	COG2322	membrane
FOC06_RS13640	COG1113	amino acid transport
FOC06_RS13650	COG1408	metallophosphoesterase
FOC06_RS13655	COG2116	formate transmembrane transporter activity
FOC06_RS13665	COG2217	Heavy metal translocating P-type atpase
FOC06_RS13670	COG2608	mercury ion transmembrane transporter activity
FOC06_RS13675	COG1937	Protein conserved in bacteria
FOC06_RS13685	COG2819	hydrolase of the alpha beta superfamily
FOC06_RS13690	COG1120	ATPase activity
FOC06_RS13695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS13700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS13710	COG0708	Exodeoxyribonuclease III
FOC06_RS13715	COG2169	Transcriptional regulator
FOC06_RS13720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC06_RS13725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC06_RS13735	COG2364	Membrane
FOC06_RS13750	COG2267	carboxylic ester hydrolase activity
FOC06_RS13755	COG0346	lactoylglutathione lyase activity
FOC06_RS13760	COG5001	Diguanylate cyclase
FOC06_RS13760	COG3300	MHYT domain
FOC06_RS13775	COG1346	cytolysis
FOC06_RS13780	COG1380	Effector of murein hydrolase LrgA
FOC06_RS13785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS13790	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC06_RS13790	COG0596	Alpha beta hydrolase
FOC06_RS13795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC06_RS13815	COG1404	Belongs to the peptidase S8 family
FOC06_RS13820	COG3773	Cell wall hydrolase
FOC06_RS13825	COG0562	UDP-galactopyranose mutase
FOC06_RS13830	COG1368	sulfuric ester hydrolase activity
FOC06_RS13835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC06_RS13845	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC06_RS13890	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC06_RS13895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC06_RS13900	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC06_RS13905	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC06_RS13905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC06_RS13915	COG2359	stage V sporulation protein S
FOC06_RS13920	COG1692	metallophosphoesterase
FOC06_RS13945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC06_RS13950	COG1426	Protein conserved in bacteria
FOC06_RS13965	COG0300	oxidoreductase activity
FOC06_RS13970	COG0612	Peptidase, M16
FOC06_RS13975	COG0612	Peptidase, M16
FOC06_RS14000	COG2188	Transcriptional regulator
FOC06_RS14005	COG1674	ftsk spoiiie
FOC06_RS14015	COG0740	serine-type endopeptidase activity
FOC06_RS14020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC06_RS14030	COG0527	aspartate kinase activity
FOC06_RS14035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC06_RS14040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC06_RS14045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC06_RS14050	COG1873	PFAM PRC-barrel domain
FOC06_RS14055	COG0612	Peptidase, M16
FOC06_RS14060	COG0726	polysaccharide deacetylase
FOC06_RS14075	COG0196	riboflavin kinase activity
FOC06_RS14080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC06_RS14090	COG1550	Protein conserved in bacteria
FOC06_RS14100	COG1358	cellular component organization or biogenesis
FOC06_RS14105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC06_RS14110	COG0195	Participates in both transcription termination and antitermination
FOC06_RS14130	COG0750	zinc metalloprotease
FOC06_RS14135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC06_RS14140	COG4589	Belongs to the CDS family
FOC06_RS14145	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC06_RS14155	COG0528	UMP kinase activity
FOC06_RS14185	COG4974	Belongs to the 'phage' integrase family
FOC06_RS14195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC06_RS14205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC06_RS14245	COG1837	Belongs to the UPF0109 family
FOC06_RS14255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC06_RS14265	COG0552	protein localization to endoplasmic reticulum
FOC06_RS14270	COG1196	nuclear chromosome segregation
FOC06_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS14290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC06_RS14305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC06_RS14310	COG1461	Dihydroxyacetone kinase
FOC06_RS14315	COG1302	Protein conserved in bacteria
FOC06_RS14330	COG1564	THIamine pyrophosphokinase
FOC06_RS14335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC06_RS14340	COG1162	GTPase activity
FOC06_RS14345	COG2815	serine threonine protein kinase
FOC06_RS14345	COG0515	serine threonine protein kinase
FOC06_RS14350	COG0631	protein serine/threonine phosphatase activity
FOC06_RS14360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC06_RS14360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC06_RS14370	COG0242	peptide deformylase activity
FOC06_RS14375	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC06_RS14380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC06_RS14390	COG0194	GDP metabolic process
FOC06_RS14400	COG1561	YicC-like family, N-terminal region
FOC06_RS14405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC06_RS14415	COG0006	proline dipeptidase activity
FOC06_RS14430	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC06_RS14470	COG0505	Belongs to the CarA family
FOC06_RS14495	COG0564	pseudouridine synthase activity
FOC06_RS14515	COG3599	regulation of cell shape
FOC06_RS14520	COG2302	S4 RNA-binding domain
FOC06_RS14525	COG0762	integral membrane protein
FOC06_RS14535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC06_RS14545	COG1873	PFAM PRC-barrel domain
FOC06_RS14550	COG1191	sigma factor activity
FOC06_RS14555	COG1191	sigma factor activity
FOC06_RS14565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC06_RS14570	COG0849	cell division
FOC06_RS14575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC06_RS14580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC06_RS14585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC06_RS14590	COG0772	Belongs to the SEDS family
FOC06_RS14605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC06_RS14610	COG0768	penicillin binding
FOC06_RS14620	COG4839	cell division protein FtsL
FOC06_RS14635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC06_RS14660	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC06_RS14710	COG4824	toxin secretion phage lysis holin
FOC06_RS14800	COG4626	Terminase
FOC06_RS14800	COG1802	Transcriptional regulator
FOC06_RS14825	COG0582	viral genome integration into host DNA
FOC06_RS14900	COG1191	sigma factor activity
FOC06_RS14925	COG1484	DNA-dependent DNA replication
FOC06_RS14945	COG1396	sequence-specific DNA binding
FOC06_RS14955	COG1396	sequence-specific DNA binding
FOC06_RS14965	COG0582	viral genome integration into host DNA
FOC06_RS14975	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC06_RS14980	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC06_RS14985	COG3314	Sporulation integral membrane protein YlbJ
FOC06_RS14995	COG0742	ribosomal rna small subunit methyltransferase
FOC06_RS15010	COG3679	Belongs to the UPF0342 family
FOC06_RS15015	COG0406	alpha-ribazole phosphatase activity
FOC06_RS15030	COG2340	Cysteine-rich secretory protein family
FOC06_RS15045	COG3336	cytochrome c oxidase
FOC06_RS15080	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC06_RS15090	COG4838	Belongs to the UPF0358 family
FOC06_RS15095	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC06_RS15100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC06_RS15110	COG4896	Protein conserved in bacteria
FOC06_RS15135	COG0483	inositol monophosphate 1-phosphatase activity
FOC06_RS15155	COG1982	Orn Lys Arg decarboxylase major
FOC06_RS15200	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC06_RS15205	COG0022	dehydrogenase e1 component
FOC06_RS15210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC06_RS15220	COG0242	peptide deformylase activity
FOC06_RS15235	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC06_RS15240	COG0569	domain protein
FOC06_RS15260	COG0583	DNA-binding transcription factor activity
FOC06_RS15265	COG0517	IMP dehydrogenase activity
FOC06_RS15275	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC06_RS15280	COG4703	Protein of unknown function (DUF1797)
FOC06_RS15295	COG2200	EAL domain
FOC06_RS15300	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS15305	COG1408	metallophosphoesterase
FOC06_RS15315	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC06_RS15350	COG2814	Major facilitator Superfamily
FOC06_RS15370	COG3209	COG3209 Rhs family protein
FOC06_RS15380	COG2205	protein histidine kinase activity
FOC06_RS15390	COG0436	Aminotransferase
FOC06_RS15395	COG1609	Transcriptional regulator
FOC06_RS15400	COG3833	ABC-type maltose transport systems, permease component
FOC06_RS15405	COG1175	transmembrane transport
FOC06_RS15410	COG2182	Extracellular solute-binding protein
FOC06_RS15420	COG0366	Alpha amylase catalytic
FOC06_RS15425	COG3842	ATPase activity
FOC06_RS15465	COG0183	Belongs to the thiolase family
FOC06_RS15505	COG1695	Transcriptional regulator
FOC06_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS15530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC06_RS15535	COG0436	Aminotransferase
FOC06_RS15555	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC06_RS15575	COG3706	GGDEF domain
FOC06_RS15580	COG0778	Nitroreductase
FOC06_RS15605	COG2190	(PTS) system
FOC06_RS15605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC06_RS15605	COG1263	PTS System
FOC06_RS15610	COG3711	transcriptional antiterminator
FOC06_RS15630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC06_RS15655	COG1547	Domain of unknown function (DUF309)
FOC06_RS15660	COG0456	acetyltransferase
FOC06_RS15665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC06_RS15670	COG4086	secreted protein
FOC06_RS15675	COG0561	phosphatase activity
FOC06_RS15680	COG0697	spore germination
FOC06_RS15695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC06_RS15720	COG0733	neurotransmitter:sodium symporter activity
FOC06_RS15740	COG1686	Belongs to the peptidase S11 family
FOC06_RS15745	COG1725	Transcriptional regulator
FOC06_RS15750	COG1131	(ABC) transporter
FOC06_RS15765	COG1846	Transcriptional regulator
FOC06_RS15780	COG0598	Magnesium transport protein CorA
FOC06_RS15805	COG4974	Belongs to the 'phage' integrase family
FOC06_RS15815	COG0735	belongs to the Fur family
FOC06_RS15820	COG1300	Membrane
FOC06_RS15840	COG0667	Aldo Keto reductase
FOC06_RS15845	COG0656	L-ascorbic acid biosynthetic process
FOC06_RS15850	COG0456	acetyltransferase
FOC06_RS15850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC06_RS15860	COG0737	Belongs to the 5'-nucleotidase family
FOC06_RS15860	COG1525	nuclease
FOC06_RS15860	COG4085	toxin activity
FOC06_RS15870	COG0596	Alpha beta hydrolase
FOC06_RS15875	COG2056	Na+-H+ antiporter family
FOC06_RS15880	COG1609	Transcriptional regulator
FOC06_RS15885	COG0456	acetyltransferase
FOC06_RS15890	COG1073	alpha beta
FOC06_RS15905	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC06_RS15905	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC06_RS15910	COG0307	riboflavin synthase, alpha
FOC06_RS15930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC06_RS15935	COG4106	trans-aconitate 2-methyltransferase activity
FOC06_RS15940	COG1073	alpha beta
FOC06_RS15940	COG2226	methyltransferase
FOC06_RS15945	COG0156	8-amino-7-oxononanoate synthase activity
FOC06_RS15955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC06_RS15970	COG0737	Belongs to the 5'-nucleotidase family
FOC06_RS15980	COG1522	sequence-specific DNA binding
FOC06_RS16000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC06_RS16010	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC06_RS16025	COG0300	oxidoreductase activity
FOC06_RS16035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC06_RS16040	COG1760	l-serine dehydratase
FOC06_RS16045	COG1760	l-serine dehydratase
FOC06_RS16065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC06_RS16075	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC06_RS16080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS16095	COG1376	ErfK ybiS ycfS ynhG family protein
FOC06_RS16100	COG4129	membrane
FOC06_RS16105	COG1126	abc transporter atp-binding protein
FOC06_RS16110	COG0765	amino acid transport
FOC06_RS16115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC06_RS16135	COG0772	Belongs to the SEDS family
FOC06_RS16140	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC06_RS16145	COG0022	dehydrogenase e1 component
FOC06_RS16150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC06_RS16155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC06_RS16165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC06_RS16170	COG0280	phosphate acetyltransferase
FOC06_RS16175	COG3829	transcription factor binding
FOC06_RS16175	COG3290	protein histidine kinase activity
FOC06_RS16185	COG0584	glycerophosphoryl diester phosphodiesterase
FOC06_RS16190	COG3093	addiction module antidote protein HigA
FOC06_RS16200	COG0745	RESPONSE REGULATOR receiver
FOC06_RS16205	COG0750	zinc metalloprotease
FOC06_RS16210	COG0497	DNA recombination
FOC06_RS16220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC06_RS16230	COG0142	geranyltranstransferase activity
FOC06_RS16255	COG1302	Protein conserved in bacteria
FOC06_RS16260	COG0439	Biotin carboxylase
FOC06_RS16265	COG0511	ligase activity, forming carbon-carbon bonds
FOC06_RS16310	COG3854	ATPases associated with a variety of cellular activities
FOC06_RS16335	COG0006	proline dipeptidase activity
FOC06_RS16350	COG3872	metal-dependent enzyme
FOC06_RS16360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC06_RS16380	COG0095	Lipoate-protein ligase
FOC06_RS16385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC06_RS16390	COG1609	Transcriptional regulator
FOC06_RS16400	COG2076	Multidrug Resistance protein
FOC06_RS16405	COG2076	Multidrug Resistance protein
FOC06_RS16440	COG1131	(ABC) transporter
FOC06_RS16445	COG1725	Transcriptional regulator
FOC06_RS16475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC06_RS16530	COG4970	Tfp pilus assembly protein FimT
FOC06_RS16540	COG1459	type II secretion system
FOC06_RS16545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC06_RS16595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC06_RS16600	COG1410	methionine synthase
FOC06_RS16600	COG0646	methionine synthase
FOC06_RS16605	COG0646	methionine synthase
FOC06_RS16605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC06_RS16610	COG0626	cystathionine gamma-synthase activity
FOC06_RS16615	COG0626	cystathionine gamma-synthase activity
FOC06_RS16635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS16645	COG1940	carbohydrate kinase activity
FOC06_RS16650	COG4483	Protein conserved in bacteria
FOC06_RS16655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC06_RS16665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC06_RS16670	COG0704	Plays a role in the regulation of phosphate uptake
FOC06_RS16675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC06_RS16680	COG0581	inorganic phosphate transmembrane transporter activity
FOC06_RS16685	COG0573	inorganic phosphate transmembrane transporter activity
FOC06_RS16690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC06_RS16700	COG0477	Major facilitator Superfamily
FOC06_RS16705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC06_RS16730	COG0735	belongs to the Fur family
FOC06_RS16735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC06_RS16740	COG1121	(ABC) transporter
FOC06_RS16745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS16775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC06_RS16780	COG2384	SAM-dependent methyltransferase
FOC06_RS16785	COG2010	Cytochrome c
FOC06_RS16790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC06_RS16795	COG0358	DNA primase activity
FOC06_RS16805	COG0517	IMP dehydrogenase activity
FOC06_RS16820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC06_RS16825	COG0295	cytidine deaminase activity
FOC06_RS16830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC06_RS16840	COG1480	7TM receptor with intracellular HD hydrolase
FOC06_RS16845	COG1702	phosphate starvation-inducible protein PhoH
FOC06_RS16860	COG1610	YqeY-like protein
FOC06_RS16870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC06_RS16875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC06_RS16895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC06_RS16905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC06_RS16910	COG1733	regulation of RNA biosynthetic process
FOC06_RS16935	COG1466	dna polymerase III delta subunit
FOC06_RS16945	COG0658	competence protein
FOC06_RS16945	COG2333	competence protein COMEC
FOC06_RS16950	COG2131	deaminase
FOC06_RS16955	COG1596	polysaccharide export
FOC06_RS16955	COG1555	photosystem II stabilization
FOC06_RS16960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC06_RS16965	COG2226	methyltransferase
FOC06_RS16970	COG0799	negative regulation of ribosome biogenesis
FOC06_RS16975	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC06_RS16985	COG1534	Rna-binding protein
FOC06_RS16995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC06_RS17000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC06_RS17015	COG1191	sigma factor activity
FOC06_RS17025	COG1595	DNA-templated transcription, initiation
FOC06_RS17035	COG0778	Nitroreductase
FOC06_RS17040	COG2357	RelA SpoT domain protein
FOC06_RS17050	COG1785	Belongs to the alkaline phosphatase family
FOC06_RS17060	COG2267	carboxylic ester hydrolase activity
FOC06_RS17095	COG1404	Belongs to the peptidase S8 family
FOC06_RS17100	COG3186	Phenylalanine-4-hydroxylase
FOC06_RS17115	COG2259	Doxx family
FOC06_RS17155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS17165	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS17165	COG1454	alcohol dehydrogenase
FOC06_RS17170	COG0626	cystathionine gamma-synthase activity
FOC06_RS17175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC06_RS17200	COG0768	penicillin binding
FOC06_RS17230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC06_RS17250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC06_RS17260	COG0628	permease
FOC06_RS17280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC06_RS17290	COG0482	sulfurtransferase activity
FOC06_RS17295	COG1104	cysteine desulfurase activity
FOC06_RS17300	COG1959	2 iron, 2 sulfur cluster binding
FOC06_RS17305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC06_RS17315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC06_RS17325	COG0124	histidyl-tRNA synthetase
FOC06_RS17335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC06_RS17345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC06_RS17345	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC06_RS17350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC06_RS17355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC06_RS17355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC06_RS17365	COG2244	polysaccharide biosynthetic process
FOC06_RS17370	COG2323	membrane
FOC06_RS17380	COG1862	Preprotein translocase
FOC06_RS17410	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC06_RS17420	COG0697	spore germination
FOC06_RS17425	COG0697	spore germination
FOC06_RS17430	COG0640	Transcriptional regulator
FOC06_RS17455	COG0157	Belongs to the NadC ModD family
FOC06_RS17460	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC06_RS17465	COG1104	cysteine desulfurase activity
FOC06_RS17470	COG1827	regulation of RNA biosynthetic process
FOC06_RS17475	COG2258	MOSC domain
FOC06_RS17480	COG0077	Prephenate dehydratase
FOC06_RS17485	COG0577	efflux transmembrane transporter activity
FOC06_RS17490	COG0577	efflux transmembrane transporter activity
FOC06_RS17495	COG1136	(ABC) transporter
FOC06_RS17505	COG0745	RESPONSE REGULATOR receiver
FOC06_RS17510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC06_RS17525	COG2868	ribosomal protein
FOC06_RS17535	COG1530	ribonuclease E activity
FOC06_RS17540	COG1994	Peptidase M50
FOC06_RS17545	COG0739	heme binding
FOC06_RS17550	COG2894	cell division
FOC06_RS17565	COG1792	Involved in formation and maintenance of cell shape
FOC06_RS17570	COG1077	Cell shape determining protein MreB Mrl
FOC06_RS17590	COG0285	dihydrofolate synthase activity
FOC06_RS17595	COG0525	valine-tRNA ligase activity
FOC06_RS17605	COG1388	LysM domain
FOC06_RS17615	COG0113	porphobilinogen synthase activity
FOC06_RS17620	COG1587	Uroporphyrinogen-III synthase
FOC06_RS17630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC06_RS17640	COG1846	Transcriptional regulator
FOC06_RS17645	COG1764	response to oxidative stress
FOC06_RS17660	COG0470	DNA polymerase III
FOC06_RS17660	COG1067	ATP-dependent peptidase activity
FOC06_RS17705	COG0622	Phosphoesterase
FOC06_RS17710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC06_RS17720	COG5401	PFAM Sporulation and spore germination
FOC06_RS17740	COG1309	transcriptional regulator
FOC06_RS17755	COG2197	response regulator
FOC06_RS17760	COG2233	PERMEase
FOC06_RS17770	COG0402	S-adenosylhomocysteine deaminase activity
FOC06_RS17775	COG0402	S-adenosylhomocysteine deaminase activity
FOC06_RS17795	COG0444	Belongs to the ABC transporter superfamily
FOC06_RS17800	COG4608	Belongs to the ABC transporter superfamily
FOC06_RS17810	COG3279	Response regulator of the LytR AlgR family
FOC06_RS17825	COG1983	PspC domain protein
FOC06_RS17830	COG1396	sequence-specific DNA binding
FOC06_RS17835	COG0697	spore germination
FOC06_RS17845	COG1959	2 iron, 2 sulfur cluster binding
FOC06_RS17850	COG1668	transmembrane transport
FOC06_RS17855	COG4152	abc transporter atp-binding protein
FOC06_RS17860	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC06_RS17870	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC06_RS17875	COG1876	peptidase activity
FOC06_RS17880	COG0824	Thioesterase
FOC06_RS17885	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC06_RS17890	COG1053	succinate dehydrogenase
FOC06_RS17895	COG2009	succinate dehydrogenase
FOC06_RS17900	COG1719	4-vinyl reductase, 4VR
FOC06_RS17910	COG3118	belongs to the thioredoxin family
FOC06_RS17915	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC06_RS17920	COG2086	electron transfer activity
FOC06_RS17925	COG1024	Enoyl-CoA hydratase
FOC06_RS17930	COG1309	transcriptional regulator
FOC06_RS17935	COG0318	PFAM AMP-dependent synthetase and ligase
FOC06_RS17955	COG2318	DinB family
FOC06_RS17980	COG1131	(ABC) transporter
FOC06_RS17985	COG2205	protein histidine kinase activity
FOC06_RS17990	COG0745	RESPONSE REGULATOR receiver
FOC06_RS17995	COG4895	conserved protein (DUF2196)
FOC06_RS18000	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC06_RS18015	COG4509	Sortase family
FOC06_RS18020	COG1120	ATPase activity
FOC06_RS18035	COG5386	Cell surface protein
FOC06_RS18045	COG5386	Cell surface protein
FOC06_RS18050	COG1114	Component of the transport system for branched-chain amino acids
FOC06_RS18055	COG1187	pseudouridine synthase activity
FOC06_RS18065	COG1796	DNA polymerase
FOC06_RS18065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC06_RS18070	COG1286	toxin biosynthetic process
FOC06_RS18100	COG0017	Asparaginyl-tRNA synthetase
FOC06_RS18105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC06_RS18105	COG0072	phenylalanine-tRNA ligase activity
FOC06_RS18115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC06_RS18125	COG1418	mRNA catabolic process
FOC06_RS18150	COG2814	Major facilitator Superfamily
FOC06_RS18155	COG1566	PFAM secretion protein HlyD family protein
FOC06_RS18160	COG1309	transcriptional regulator
FOC06_RS18165	COG1363	Peptidase, m42
FOC06_RS18185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC06_RS18190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC06_RS18200	COG1484	DNA-dependent DNA replication
FOC06_RS18205	COG3611	Membrane attachment protein
FOC06_RS18215	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC06_RS18225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC06_RS18230	COG0237	dephospho-CoA kinase activity
FOC06_RS18235	COG1971	Probably functions as a manganese efflux pump
FOC06_RS18240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC06_RS18245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC06_RS18245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC06_RS18250	COG5002	protein histidine kinase activity
FOC06_RS18255	COG0745	RESPONSE REGULATOR receiver
FOC06_RS18270	COG0538	isocitrate dehydrogenase activity
FOC06_RS18275	COG0372	Belongs to the citrate synthase family
FOC06_RS18285	COG0628	permease
FOC06_RS18290	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC06_RS18315	COG1725	Transcriptional regulator
FOC06_RS18320	COG0281	malic enzyme
FOC06_RS18325	COG0587	DNA-directed DNA polymerase activity
FOC06_RS18340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC06_RS18360	COG4109	DRTGG domain
FOC06_RS18375	COG0006	proline dipeptidase activity
FOC06_RS18410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS18415	COG0662	Cupin 2, conserved barrel domain protein
FOC06_RS18425	COG1476	TRANSCRIPTIONal
FOC06_RS18440	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS18445	COG0589	response to stress
FOC06_RS18485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS18505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC06_RS18510	COG0827	DNA restriction-modification system
FOC06_RS18515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC06_RS18520	COG3874	Sporulation protein YtfJ
FOC06_RS18530	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC06_RS18535	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC06_RS18545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC06_RS18560	COG1104	cysteine desulfurase activity
FOC06_RS18570	COG0583	DNA-binding transcription factor activity
FOC06_RS18575	COG0697	spore germination
FOC06_RS18585	COG1956	GAF domain-containing protein
FOC06_RS18590	COG0626	cystathionine gamma-synthase activity
FOC06_RS18610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC06_RS18620	COG1595	DNA-templated transcription, initiation
FOC06_RS18635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC06_RS18640	COG0454	-acetyltransferase
FOC06_RS18645	COG0517	IMP dehydrogenase activity
FOC06_RS18650	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC06_RS18660	COG0745	RESPONSE REGULATOR receiver
FOC06_RS18670	COG0666	response to abiotic stimulus
FOC06_RS18705	COG1609	Transcriptional regulator
FOC06_RS18710	COG4851	CamS sex pheromone cAM373 precursor
FOC06_RS18715	COG3118	belongs to the thioredoxin family
FOC06_RS18725	COG2309	aminopeptidase activity
FOC06_RS18745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS18760	COG1674	ftsk spoiiie
FOC06_RS18770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC06_RS18775	COG4848	Belongs to the UPF0354 family
FOC06_RS18780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC06_RS18785	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC06_RS18790	COG1363	Peptidase, m42
FOC06_RS18800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS18815	COG0510	thiamine kinase activity
FOC06_RS18820	COG1523	belongs to the glycosyl hydrolase 13 family
FOC06_RS18835	COG1349	DNA-binding transcription factor activity
FOC06_RS18840	COG1187	pseudouridine synthase activity
FOC06_RS18845	COG2244	polysaccharide biosynthetic process
FOC06_RS18850	COG2081	HI0933 family
FOC06_RS18855	COG2814	Major facilitator Superfamily
FOC06_RS18865	COG3832	glyoxalase III activity
FOC06_RS18885	COG1329	Transcriptional regulator
FOC06_RS18895	COG4975	Glucose uptake
FOC06_RS18910	COG0314	molybdopterin synthase activity
FOC06_RS18915	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC06_RS18920	COG0303	'Molybdopterin
FOC06_RS18930	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC06_RS18955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC06_RS18965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC06_RS19005	COG2814	Major facilitator Superfamily
FOC06_RS19010	COG0475	glutathione-regulated potassium exporter activity
FOC06_RS19015	COG0490	domain, Protein
FOC06_RS19020	COG0582	viral genome integration into host DNA
FOC06_RS19030	COG1136	(ABC) transporter
FOC06_RS19050	COG1242	4 iron, 4 sulfur cluster binding
FOC06_RS19055	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC06_RS19060	COG1131	(ABC) transporter
FOC06_RS19070	COG1794	racemase activity, acting on amino acids and derivatives
FOC06_RS19090	COG2267	carboxylic ester hydrolase activity
FOC06_RS19095	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC06_RS19100	COG0671	phosphoesterase, PA-phosphatase related
FOC06_RS19105	COG0438	transferase activity, transferring glycosyl groups
FOC06_RS19115	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC06_RS19165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC06_RS19170	COG5002	protein histidine kinase activity
FOC06_RS19175	COG4191	Histidine kinase
FOC06_RS19180	COG2267	carboxylic ester hydrolase activity
FOC06_RS19200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC06_RS19205	COG1116	anion transmembrane transporter activity
FOC06_RS19210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC06_RS19235	COG0494	nUDIX hydrolase
FOC06_RS19265	COG0288	reversible hydration of carbon dioxide
FOC06_RS19270	COG1271	oxidase subunit
FOC06_RS19275	COG1294	oxidase, subunit
FOC06_RS19295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS19320	COG1842	Phage shock protein A
FOC06_RS19355	COG5002	protein histidine kinase activity
FOC06_RS19360	COG0745	RESPONSE REGULATOR receiver
FOC06_RS19390	COG1597	lipid kinase activity
FOC06_RS19425	COG0586	Pfam SNARE associated Golgi protein
FOC06_RS19435	COG0577	efflux transmembrane transporter activity
FOC06_RS19440	COG1136	(ABC) transporter
FOC06_RS19445	COG2207	Transcriptional regulator
FOC06_RS19445	COG3708	Transcriptional regulator
FOC06_RS19450	COG0745	RESPONSE REGULATOR receiver
FOC06_RS19455	COG2205	protein histidine kinase activity
FOC06_RS19465	COG0577	efflux transmembrane transporter activity
FOC06_RS19470	COG1136	(ABC) transporter
FOC06_RS19510	COG3964	amidohydrolase
FOC06_RS19540	COG4948	Mandelate Racemase Muconate Lactonizing
FOC06_RS19550	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC06_RS19555	COG0596	Alpha beta hydrolase
FOC06_RS19560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC06_RS19565	COG1169	isochorismate synthase
FOC06_RS19570	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC06_RS19575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC06_RS19580	COG1278	Cold shock
FOC06_RS19595	COG0058	SHG alpha-glucan phosphorylase activity
FOC06_RS19600	COG0297	glycogen (starch) synthase activity
FOC06_RS19605	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC06_RS19610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC06_RS19630	COG0039	L-malate dehydrogenase activity
FOC06_RS19725	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC06_RS19760	COG1285	pathogenesis
FOC06_RS19765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC06_RS19775	COG0166	Belongs to the GPI family
FOC06_RS19780	COG2155	Conserved Protein
FOC06_RS19785	COG1098	S1 RNA binding domain
FOC06_RS19790	COG0436	Aminotransferase
FOC06_RS19795	COG1522	sequence-specific DNA binding
FOC06_RS19800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC06_RS19805	COG2267	carboxylic ester hydrolase activity
FOC06_RS19815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC06_RS19830	COG5018	Exonuclease
FOC06_RS19835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC06_RS19850	COG0423	glycine-tRNA ligase activity
FOC06_RS19855	COG2050	protein possibly involved in aromatic compounds catabolism
FOC06_RS19865	COG1268	BioY protein
FOC06_RS19875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC06_RS19880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC06_RS19895	COG3584	3D domain protein
FOC06_RS19910	COG1252	NADH dehydrogenase
FOC06_RS19925	COG3708	Transcriptional regulator
FOC06_RS19940	COG1683	Conserved Protein
FOC06_RS19960	COG0316	Belongs to the HesB IscA family
FOC06_RS19975	COG1252	NADH dehydrogenase
FOC06_RS19990	COG0390	transport system, permease component
FOC06_RS19995	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC06_RS20035	COG4837	Protein of unknown function (DUF1462)
FOC06_RS20040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC06_RS20050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC06_RS20055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC06_RS20065	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC06_RS20070	COG0647	UMP catabolic process
FOC06_RS20080	COG2445	Protein of unknown function DUF86
FOC06_RS20085	COG1494	fructose-1,6-bisphosphatase
FOC06_RS20100	COG4470	Protein conserved in bacteria
FOC06_RS20110	COG0789	Transcriptional regulator
FOC06_RS20115	COG4377	Putative membrane peptidase family (DUF2324)
FOC06_RS20140	COG0739	heme binding
FOC06_RS20150	COG3377	Domain of unknown function (DUF1805)
FOC06_RS20155	COG0737	Belongs to the 5'-nucleotidase family
FOC06_RS20160	COG1695	Transcriptional regulator
FOC06_RS20170	COG0719	Fe-S assembly protein
FOC06_RS20175	COG0822	iron-sulfur transferase activity
FOC06_RS20180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC06_RS20185	COG0719	Fe-S assembly protein
FOC06_RS20190	COG0396	ATPase activity
FOC06_RS20195	COG1464	Belongs to the NlpA lipoprotein family
FOC06_RS20200	COG1464	Belongs to the NlpA lipoprotein family
FOC06_RS20205	COG2011	ABC-type metal ion transport system permease component
FOC06_RS20210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC06_RS20220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC06_RS20225	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC06_RS20240	COG1393	Belongs to the ArsC family
FOC06_RS20285	COG0039	L-malate dehydrogenase activity
FOC06_RS20305	COG1309	transcriptional regulator
FOC06_RS20310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS20315	COG1960	acyl-CoA dehydrogenase activity
FOC06_RS20320	COG0183	Belongs to the thiolase family
FOC06_RS20325	COG1024	Enoyl-CoA hydratase
FOC06_RS20325	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC06_RS20335	COG1686	Belongs to the peptidase S11 family
FOC06_RS20350	COG0011	TIGRFAM Protein of
FOC06_RS20355	COG0840	transmembrane signaling receptor activity
FOC06_RS20370	COG2814	Major facilitator Superfamily
FOC06_RS20375	COG0531	amino acid
FOC06_RS20385	COG0706	membrane insertase activity
FOC06_RS20395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS20430	COG0586	Pfam SNARE associated Golgi protein
FOC06_RS20440	COG1376	ErfK ybiS ycfS ynhG family protein
FOC06_RS20445	COG0745	RESPONSE REGULATOR receiver
FOC06_RS20450	COG5002	protein histidine kinase activity
FOC06_RS20460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC06_RS20475	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC06_RS20480	COG3227	Zinc metalloprotease (Elastase)
FOC06_RS20485	COG1741	Belongs to the pirin family
FOC06_RS20500	COG0475	glutathione-regulated potassium exporter activity
FOC06_RS20505	COG0490	domain, Protein
FOC06_RS20510	COG1115	amino acid carrier protein
FOC06_RS20515	COG0783	Belongs to the Dps family
FOC06_RS20530	COG1611	Belongs to the LOG family
FOC06_RS20550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS20555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS20560	COG1115	amino acid carrier protein
FOC06_RS20565	COG1115	amino acid carrier protein
FOC06_RS20570	COG2910	NAD(P)H-binding
FOC06_RS20585	COG0656	L-ascorbic acid biosynthetic process
FOC06_RS20590	COG2814	Major facilitator Superfamily
FOC06_RS20595	COG1733	regulation of RNA biosynthetic process
FOC06_RS20605	COG1252	NADH dehydrogenase
FOC06_RS20610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC06_RS20615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC06_RS20625	COG3290	protein histidine kinase activity
FOC06_RS20625	COG0840	transmembrane signaling receptor activity
FOC06_RS20635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC06_RS20640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC06_RS20655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC06_RS20660	COG3223	Belongs to the PsiE family
FOC06_RS20710	COG0557	exoribonuclease II activity
FOC06_RS20715	COG1647	Serine aminopeptidase, S33
FOC06_RS20720	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC06_RS20725	COG1346	cytolysis
FOC06_RS20820	COG4695	Portal protein
FOC06_RS20845	COG4974	Belongs to the 'phage' integrase family
FOC06_RS20855	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC06_RS20860	COG0149	triose-phosphate isomerase activity
FOC06_RS20870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC06_RS20885	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC06_RS20910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC06_RS20925	COG2323	membrane
FOC06_RS20930	COG0740	serine-type endopeptidase activity
FOC06_RS20935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC06_RS20945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC06_RS20955	COG1051	belongs to the nudix hydrolase family
FOC06_RS20965	COG0492	ferredoxin-NADP+ reductase activity
FOC06_RS20970	COG0457	Tetratricopeptide repeat
FOC06_RS20975	COG0110	maltose O-acetyltransferase activity
FOC06_RS20995	COG1950	PFAM Membrane protein of
FOC06_RS21005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC06_RS21010	COG0556	nucleotide-excision repair
FOC06_RS21030	COG0789	Transcriptional regulator
FOC06_RS21055	COG2855	membrane
FOC06_RS21060	COG0583	DNA-binding transcription factor activity
FOC06_RS21070	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC06_RS21085	COG1132	(ABC) transporter
FOC06_RS21090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC06_RS21095	COG3409	Peptidoglycan-binding domain 1 protein
FOC06_RS21095	COG0793	Belongs to the peptidase S41A family
FOC06_RS21100	COG2177	Part of the ABC transporter FtsEX involved in
FOC06_RS21105	COG2884	Cell division ATP-binding protein ftsE
FOC06_RS21125	COG0653	protein targeting
FOC06_RS21130	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC06_RS21135	COG1278	Cold shock
FOC06_RS21140	COG1040	competence protein
FOC06_RS21145	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC06_RS21150	COG1388	LysM domain
FOC06_RS21150	COG0791	NLP P60 protein
FOC06_RS21155	COG1733	regulation of RNA biosynthetic process
FOC06_RS21160	COG1307	EDD domain protein, DegV family
FOC06_RS21165	COG1739	Uncharacterized protein family UPF0029
FOC06_RS21170	COG1316	TRANSCRIPTIONal
FOC06_RS21175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC06_RS21180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC06_RS21185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC06_RS21195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC06_RS21195	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC06_RS21210	COG3394	polysaccharide catabolic process
FOC06_RS21215	COG1486	melibiose metabolic process
FOC06_RS21220	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC06_RS21225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC06_RS21235	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC06_RS21240	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC06_RS21245	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC06_RS21255	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC06_RS21260	COG1301	dicarboxylic acid transport
FOC06_RS21270	COG0346	lactoylglutathione lyase activity
FOC06_RS21275	COG1511	domain protein
FOC06_RS21280	COG0583	DNA-binding transcription factor activity
FOC06_RS21285	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC06_RS21300	COG1271	oxidase subunit
FOC06_RS21305	COG1294	oxidase, subunit
FOC06_RS21310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC06_RS21320	COG1620	l-lactate permease
FOC06_RS21330	COG2389	metal-binding protein
FOC06_RS21340	COG1368	sulfuric ester hydrolase activity
FOC06_RS21355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS21370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC06_RS21375	COG1388	LysM domain
FOC06_RS21375	COG3584	3D domain protein
FOC06_RS21400	COG4715	Zinc finger, swim domain protein
FOC06_RS21405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC06_RS21435	COG1191	sigma factor activity
FOC06_RS21445	COG0577	efflux transmembrane transporter activity
FOC06_RS21450	COG1136	(ABC) transporter
FOC06_RS21485	COG5002	protein histidine kinase activity
FOC06_RS21490	COG0745	RESPONSE REGULATOR receiver
FOC06_RS21495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC06_RS21510	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC06_RS21515	COG1134	teichoic acid transport
FOC06_RS21520	COG1682	transport, permease protein
FOC06_RS21525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC06_RS21570	COG1609	Transcriptional regulator
FOC06_RS21585	COG0739	heme binding
FOC06_RS21605	COG2385	sporulation resulting in formation of a cellular spore
FOC06_RS21610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC06_RS21620	COG4836	Membrane
FOC06_RS21625	COG1007	ATP synthesis coupled electron transport
FOC06_RS21630	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC06_RS21635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC06_RS21645	COG0839	Belongs to the complex I subunit 6 family
FOC06_RS21660	COG0649	NAD binding
FOC06_RS21665	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC06_RS21675	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC06_RS21680	COG5001	Diguanylate cyclase
FOC06_RS21680	COG3300	MHYT domain
FOC06_RS21730	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC06_RS21765	COG0698	ribose 5-phosphate isomerase
FOC06_RS21775	COG2190	(PTS) system
FOC06_RS21780	COG2259	Doxx family
FOC06_RS21785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC06_RS21800	COG0009	L-threonylcarbamoyladenylate synthase
FOC06_RS21815	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC06_RS21820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC06_RS21835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC06_RS21840	COG1494	fructose-1,6-bisphosphatase
FOC06_RS21845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC06_RS21860	COG4821	SIS domain
FOC06_RS21870	COG3343	RNA polymerase activity
FOC06_RS21880	COG1960	acyl-CoA dehydrogenase activity
FOC06_RS21885	COG1960	acyl-CoA dehydrogenase activity
FOC06_RS21890	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC06_RS21895	COG0183	Belongs to the thiolase family
FOC06_RS21900	COG0247	lactate metabolic process
FOC06_RS21900	COG2181	nitrate reductase activity
FOC06_RS21905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC06_RS21915	COG5001	Diguanylate cyclase
FOC06_RS21915	COG3300	MHYT domain
FOC06_RS21935	COG2197	response regulator
FOC06_RS21940	COG4585	Histidine kinase
FOC06_RS21945	COG0842	Transport permease protein
FOC06_RS21950	COG1131	(ABC) transporter
FOC06_RS21955	COG0024	Methionine aminopeptidase
FOC06_RS21965	COG2234	aminopeptidase activity
FOC06_RS21985	COG1595	DNA-templated transcription, initiation
FOC06_RS21990	COG0018	arginyl-trna synthetase
FOC06_RS21995	COG4506	Protein conserved in bacteria
FOC06_RS22000	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC06_RS22015	COG0010	Belongs to the arginase family
FOC06_RS22020	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC06_RS22025	COG2814	Major facilitator Superfamily
FOC06_RS22030	COG0789	Transcriptional regulator
FOC06_RS22035	COG0584	glycerophosphoryl diester phosphodiesterase
FOC06_RS22040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC06_RS22050	COG1994	Peptidase M50
FOC06_RS22060	COG1078	dGTPase activity
FOC06_RS22065	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS22070	COG1120	ATPase activity
FOC06_RS22075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS22100	COG0095	Lipoate-protein ligase
FOC06_RS22105	COG0280	phosphate acetyltransferase
FOC06_RS22120	COG3773	Cell wall hydrolase
FOC06_RS22130	COG2363	Small membrane protein
FOC06_RS22145	COG2233	PERMEase
FOC06_RS22150	COG0561	phosphatase activity
FOC06_RS22155	COG2814	Major facilitator Superfamily
FOC06_RS22165	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC06_RS22170	COG1131	(ABC) transporter
FOC06_RS22175	COG2755	lipolytic protein G-D-S-L family
FOC06_RS22180	COG1609	Transcriptional regulator
FOC06_RS22190	COG0460	homoserine dehydrogenase
FOC06_RS22210	COG1011	Hydrolase
FOC06_RS22215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC06_RS22225	COG2197	response regulator
FOC06_RS22235	COG0351	phosphomethylpyrimidine kinase
FOC06_RS22240	COG3706	GGDEF domain
FOC06_RS22245	COG2879	small protein
FOC06_RS22250	COG1966	Carbon starvation protein
FOC06_RS22255	COG3279	Response regulator of the LytR AlgR family
FOC06_RS22260	COG0477	Major facilitator Superfamily
FOC06_RS22285	COG0840	transmembrane signaling receptor activity
FOC06_RS22295	COG1607	acyl-coa hydrolase
FOC06_RS22310	COG0488	(ABC) transporter
FOC06_RS22330	COG0463	Glycosyl transferase, family 2
FOC06_RS22335	COG1309	transcriptional regulator
FOC06_RS22340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC06_RS22345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC06_RS22345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC06_RS22350	COG0628	permease
FOC06_RS22365	COG3279	Response regulator of the LytR AlgR family
FOC06_RS22370	COG3275	phosphorelay sensor kinase activity
FOC06_RS22375	COG2814	Major facilitator Superfamily
FOC06_RS22380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC06_RS22385	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC06_RS22390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC06_RS22410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC06_RS22415	COG1272	protein, Hemolysin III
FOC06_RS22435	COG0516	GMP reductase activity
FOC06_RS22440	COG1164	Oligoendopeptidase f
FOC06_RS22460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC06_RS22465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC06_RS22470	COG4853	Protein conserved in bacteria
FOC06_RS22475	COG4863	YycH protein
FOC06_RS22480	COG5002	protein histidine kinase activity
FOC06_RS22485	COG0745	RESPONSE REGULATOR receiver
FOC06_RS22515	COG0305	Participates in initiation and elongation during chromosome replication
FOC06_RS22525	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC06_RS22530	COG4241	membrane
FOC06_RS22540	COG0629	single-stranded DNA binding
FOC06_RS22550	COG0012	GTP binding
FOC06_RS22555	COG4481	Protein conserved in bacteria
FOC06_RS22560	COG0668	transmembrane transport
FOC06_RS22570	COG1475	DNA binding
FOC06_RS22575	COG1192	Involved in chromosome partitioning
FOC06_RS22595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC06_RS22600	COG1847	R3H domain protein
FOC06_RS22605	COG0706	membrane insertase activity
FOC06_RS22625	COG0592	DNA-directed DNA polymerase activity
FOC06_RS22630	COG2501	S4 domain
FOC06_RS22640	COG0187	DNA topoisomerase II activity
FOC06_RS22645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC06_RS22680	COG0516	GMP reductase activity
FOC06_RS22680	COG0517	IMP dehydrogenase activity
FOC06_RS22685	COG1686	Belongs to the peptidase S11 family
FOC06_RS22715	COG1428	Deoxynucleoside kinase
FOC06_RS22720	COG1428	Deoxynucleoside kinase
FOC06_RS22725	COG1335	isochorismatase
FOC06_RS22730	COG0590	tRNA wobble adenosine to inosine editing
FOC06_RS22740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC06_RS22795	COG1982	Orn Lys Arg decarboxylase major
FOC06_RS22805	COG0470	DNA polymerase III
FOC06_RS22810	COG1774	PSP1 C-terminal conserved region
FOC06_RS22820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC06_RS22830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC06_RS22835	COG2002	toxin-antitoxin pair type II binding
FOC06_RS22840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC06_RS22840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC06_RS22845	COG0084	hydrolase, TatD family'
FOC06_RS22850	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC06_RS22865	COG4466	Protein conserved in bacteria
FOC06_RS22880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC06_RS22885	COG0251	oxidation-reduction process
FOC06_RS22900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC06_RS22905	COG0193	aminoacyl-tRNA hydrolase activity
FOC06_RS22915	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC06_RS22920	COG2002	toxin-antitoxin pair type II binding
FOC06_RS22925	COG2244	polysaccharide biosynthetic process
FOC06_RS22930	COG3956	TIGRFAM MazG family protein
FOC06_RS22935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC06_RS22955	COG1098	S1 RNA binding domain
FOC06_RS22970	COG2208	phosphoserine phosphatase activity
FOC06_RS22975	COG0037	tRNA processing
FOC06_RS22985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC06_RS23000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC06_RS23005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC06_RS23010	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC06_RS23015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC06_RS23020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC06_RS23025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC06_RS23030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC06_RS23035	COG1396	sequence-specific DNA binding
FOC06_RS23040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC06_RS23070	COG3880	PFAM UvrB UvrC protein
FOC06_RS23080	COG0542	response to heat
FOC06_RS23085	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC06_RS23095	COG4956	integral membrane protein (PIN domain superfamily)
FOC06_RS23115	COG1045	serine acetyltransferase
FOC06_RS23130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC06_RS23135	COG3688	RNA-binding protein containing a PIN domain
FOC06_RS23145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC06_RS23150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC06_RS23155	COG0250	Participates in transcription elongation, termination and antitermination
FOC06_RS23180	COG2813	Specifically methylates the guanine in position
FOC06_RS23190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC06_RS23195	COG1358	cellular component organization or biogenesis
FOC06_RS23300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC06_RS23325	COG0201	protein transport
FOC06_RS23335	COG0024	Methionine aminopeptidase
FOC06_RS23345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC06_RS23375	COG1122	ATPase activity
FOC06_RS23380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC06_RS23385	COG0101	tRNA pseudouridine synthase activity
FOC06_RS23405	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC06_RS23410	COG0489	protein tyrosine kinase activity
FOC06_RS23420	COG2194	sulfuric ester hydrolase activity
FOC06_RS23425	COG0726	polysaccharide deacetylase
FOC06_RS23505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC06_RS23510	COG4856	YbbR-like protein
FOC06_RS23525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC06_RS23530	COG0596	Alpha beta hydrolase
FOC06_RS23550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC06_RS23555	COG4946	Tricorn protease homolog
FOC06_RS23555	COG0823	Involved in the tonB-independent uptake of proteins
FOC06_RS23555	COG1506	peptidase
FOC06_RS23590	COG2011	ABC-type metal ion transport system permease component
FOC06_RS23595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC06_RS23600	COG1464	Belongs to the NlpA lipoprotein family
FOC06_RS23615	COG0277	FAD linked oxidase domain protein
FOC06_RS23620	COG2271	Major facilitator Superfamily
FOC06_RS23630	COG2814	Major facilitator Superfamily
FOC06_RS23645	COG0601	transmembrane transport
FOC06_RS23650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC06_RS23655	COG0444	Belongs to the ABC transporter superfamily
FOC06_RS23660	COG4608	Belongs to the ABC transporter superfamily
FOC06_RS23665	COG4166	transmembrane transport
FOC06_RS23675	COG2207	Transcriptional regulator
FOC06_RS23690	COG4166	transmembrane transport
FOC06_RS23695	COG4166	transmembrane transport
FOC06_RS23700	COG0656	L-ascorbic acid biosynthetic process
FOC06_RS23705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC06_RS23715	COG4975	Glucose uptake
FOC06_RS23720	COG4149	molybdate abc transporter
FOC06_RS23730	COG1910	domain protein
FOC06_RS23740	COG0583	DNA-binding transcription factor activity
FOC06_RS23745	COG0697	spore germination
FOC06_RS23760	COG0204	Acyl-transferase
FOC06_RS23770	COG1609	Transcriptional regulator
FOC06_RS23780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC06_RS23790	COG0084	hydrolase, TatD family'
FOC06_RS23795	COG5298	Protein conserved in bacteria
FOC06_RS23815	COG0488	(ABC) transporter
FOC06_RS23830	COG0747	negative chemotaxis
FOC06_RS23835	COG0601	transmembrane transport
FOC06_RS23845	COG0444	Belongs to the ABC transporter superfamily
FOC06_RS23850	COG4608	Belongs to the ABC transporter superfamily
FOC06_RS23870	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC06_RS23875	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC06_RS23885	COG2814	Major facilitator Superfamily
FOC06_RS23895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC06_RS23905	COG4294	response to UV
FOC06_RS23910	COG0457	Tetratricopeptide repeat
FOC06_RS23910	COG0705	Rhomboid family
FOC06_RS23920	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC06_RS23925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC06_RS23930	COG0864	Transcriptional regulator
FOC06_RS23935	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC06_RS23940	COG2183	response to ionizing radiation
FOC06_RS24035	COG0802	atpase or kinase
FOC06_RS24040	COG1214	PFAM Peptidase M22, glycoprotease
FOC06_RS24045	COG0456	acetyltransferase
FOC06_RS24050	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC06_RS24055	COG0488	(ABC) transporter
FOC06_RS24070	COG1266	CAAX protease self-immunity
FOC06_RS24090	COG2252	PERMEase
FOC06_RS24100	COG5002	protein histidine kinase activity
FOC06_RS24130	COG2226	methyltransferase
FOC06_RS24170	COG1968	undecaprenyl-diphosphatase activity
FOC06_RS24185	COG2205	protein histidine kinase activity
FOC06_RS24190	COG0745	RESPONSE REGULATOR receiver
FOC06_RS24210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC06_RS24215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC06_RS24220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC06_RS24230	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC06_RS24245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC06_RS24255	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC06_RS24265	COG0151	Belongs to the GarS family
FOC06_RS24290	COG0210	DNA helicase
FOC06_RS24300	COG4851	CamS sex pheromone cAM373 precursor
FOC06_RS24315	COG1335	isochorismatase
FOC06_RS24320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC06_RS24325	COG2011	ABC-type metal ion transport system permease component
FOC06_RS24330	COG1464	Belongs to the NlpA lipoprotein family
FOC06_RS24350	COG1846	Transcriptional regulator
FOC06_RS24375	COG1597	lipid kinase activity
FOC06_RS24380	COG0546	phosphoglycolate phosphatase activity
FOC06_RS24385	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC06_RS24395	COG1012	belongs to the aldehyde dehydrogenase family
FOC06_RS24400	COG2076	Multidrug Resistance protein
FOC06_RS24405	COG2309	aminopeptidase activity
FOC06_RS24420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS24425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC06_RS24430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC06_RS24440	COG4807	Protein conserved in bacteria
FOC06_RS24470	COG1473	amidohydrolase
FOC06_RS24485	COG0450	alkyl hydroperoxide reductase
FOC06_RS24490	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC06_RS24500	COG0235	Class ii aldolase
FOC06_RS24505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS24510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS24515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS24530	COG0166	Belongs to the GPI family
FOC06_RS24565	COG5002	protein histidine kinase activity
FOC06_RS24585	COG3541	Predicted nucleotidyltransferase
FOC06_RS24590	COG2814	Major facilitator Superfamily
FOC06_RS24595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC06_RS24595	COG0723	plastoquinol--plastocyanin reductase activity
FOC06_RS24605	COG0765	amino acid transport
FOC06_RS24610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC06_RS24620	COG0840	transmembrane signaling receptor activity
FOC06_RS24625	COG0840	transmembrane signaling receptor activity
FOC06_RS24630	COG0366	Alpha amylase catalytic
FOC06_RS24635	COG2190	(PTS) system
FOC06_RS24635	COG1263	PTS System
FOC06_RS24635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC06_RS24665	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC06_RS24680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC06_RS24690	COG1116	anion transmembrane transporter activity
FOC06_RS24695	COG0488	(ABC) transporter
FOC06_RS24740	COG2270	Major facilitator Superfamily
FOC06_RS24755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC06_RS24770	COG2310	stress, protein
FOC06_RS24775	COG2310	stress, protein
FOC06_RS24780	COG2310	stress, protein
FOC06_RS24785	COG0861	Integral membrane protein TerC family
FOC06_RS24795	COG3853	Toxic anion resistance protein (TelA)
FOC06_RS24810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC06_RS24820	COG1295	ribonuclease BN
FOC06_RS24825	COG2217	Heavy metal translocating P-type atpase
FOC06_RS24830	COG0697	spore germination
FOC06_RS24850	COG0586	Pfam SNARE associated Golgi protein
FOC06_RS24865	COG3871	stress protein (general stress protein 26)
FOC06_RS24870	COG0387	Pfam Sodium calcium exchanger
FOC06_RS24880	COG0535	radical SAM domain protein
FOC06_RS24905	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC06_RS24910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC06_RS24915	COG0582	viral genome integration into host DNA
FOC06_RS24920	COG1396	sequence-specific DNA binding
FOC06_RS24935	COG1396	sequence-specific DNA binding
FOC06_RS24970	COG1484	DNA-dependent DNA replication
FOC06_RS25055	COG0582	viral genome integration into host DNA
FOC06_RS25060	COG0582	viral genome integration into host DNA
FOC06_RS25180	COG0101	tRNA pseudouridine synthase activity
FOC06_RS25190	COG3829	transcription factor binding
FOC06_RS25200	COG0833	amino acid
FOC06_RS25205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC06_RS25225	COG2066	Belongs to the glutaminase family
FOC06_RS25230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC06_RS25230	COG1263	PTS System
FOC06_RS25235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC06_RS25250	COG0463	Glycosyl transferase, family 2
FOC06_RS25265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC06_RS25265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC06_RS25285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC06_RS25305	COG1228	amidohydrolase
FOC06_RS25310	COG1090	epimerase
FOC06_RS25340	COG1988	membrane-bound metal-dependent
FOC06_RS25345	COG1194	a g-specific adenine glycosylase
FOC06_RS25370	COG1132	(ABC) transporter
FOC06_RS25375	COG4129	membrane
FOC06_RS25380	COG0069	glutamate synthase activity
FOC06_RS25380	COG0067	glutamate synthase
FOC06_RS25380	COG0070	glutamate synthase
FOC06_RS25390	COG4555	ABC transporter
FOC06_RS25410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC06_RS25415	COG0735	belongs to the Fur family
FOC06_RS25530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC06_RS25535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC06_RS25545	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC06_RS25555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC06_RS25565	COG2766	serine protein kinase
FOC06_RS25585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC06_RS25595	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC06_RS25600	COG2268	Band 7 protein
FOC06_RS25610	COG3290	protein histidine kinase activity
FOC06_RS25620	COG2851	Citrate transporter
FOC06_RS25640	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC06_RS25645	COG3842	ATPase activity
FOC06_RS25650	COG1175	transmembrane transport
FOC06_RS25655	COG0395	ABC-type sugar transport system, permease component
FOC06_RS25665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC06_RS25670	COG0745	RESPONSE REGULATOR receiver
FOC06_RS25675	COG5002	protein histidine kinase activity
FOC06_RS25685	COG4990	cell redox homeostasis
FOC06_RS25695	COG3290	protein histidine kinase activity
FOC06_RS25700	COG4565	transcriptional regulatory protein
FOC06_RS25705	COG3493	citrate carrier protein
FOC06_RS25710	COG0281	malic enzyme
FOC06_RS25725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC06_RS25735	COG5002	protein histidine kinase activity
FOC06_RS25740	COG0745	RESPONSE REGULATOR receiver
FOC06_RS25745	COG0456	acetyltransferase
FOC06_RS25745	COG0454	-acetyltransferase
FOC06_RS25750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC06_RS25755	COG3383	formate dehydrogenase (NAD+) activity
FOC06_RS25760	COG2427	Protein of unknown function (DUF1641)
FOC06_RS25775	COG0531	amino acid
FOC06_RS25780	COG0640	Transcriptional regulator
FOC06_RS25785	COG2217	Heavy metal translocating P-type atpase
FOC06_RS25790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC06_RS25825	COG2720	vancomycin resistance protein
FOC06_RS25830	COG1316	TRANSCRIPTIONal
FOC06_RS25835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC06_RS25840	COG0346	lactoylglutathione lyase activity
FOC06_RS25845	COG1253	flavin adenine dinucleotide binding
FOC06_RS25850	COG1027	Aspartate ammonia-lyase
FOC06_RS25855	COG1620	l-lactate permease
FOC06_RS25870	COG3104	oligopeptide transport
FOC06_RS25875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC06_RS25880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS25885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC06_RS25895	COG2226	methyltransferase
FOC06_RS25900	COG0156	8-amino-7-oxononanoate synthase activity
FOC06_RS25905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC06_RS25915	COG4548	von Willebrand factor, type A
FOC06_RS25920	COG0714	Associated with various cellular activities
FOC06_RS25925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC06_RS25945	COG0531	amino acid
FOC06_RS25950	COG2188	Transcriptional regulator
FOC06_RS25955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC06_RS25955	COG1263	PTS System
FOC06_RS25960	COG0366	Alpha amylase catalytic
FOC06_RS25975	COG0697	spore germination
FOC06_RS25985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC06_RS25990	COG1115	amino acid carrier protein
FOC06_RS25995	COG1126	abc transporter atp-binding protein
FOC06_RS26000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC06_RS26005	COG0765	amino acid transport
FOC06_RS26010	COG0765	amino acid transport
FOC06_RS26015	COG0833	amino acid
FOC06_RS26040	COG2378	regulation of single-species biofilm formation
FOC06_RS26045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC06_RS26050	COG5002	protein histidine kinase activity
FOC06_RS26065	COG0659	secondary active sulfate transmembrane transporter activity
FOC06_RS26080	COG0747	negative chemotaxis
FOC06_RS26090	COG0601	transmembrane transport
FOC06_RS26095	COG4608	Belongs to the ABC transporter superfamily
FOC06_RS26105	COG2271	Major facilitator Superfamily
FOC06_RS26110	COG1846	Transcriptional regulator
FOC06_RS26120	COG1609	Transcriptional regulator
FOC06_RS26125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC06_RS26140	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC06_RS26145	COG1879	ABC-type sugar transport system periplasmic component
FOC06_RS26150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC06_RS26170	COG1063	alcohol dehydrogenase
FOC06_RS26185	COG3568	Endonuclease Exonuclease Phosphatase
FOC06_RS26210	COG1968	undecaprenyl-diphosphatase activity
FOC06_RS26215	COG0840	transmembrane signaling receptor activity
FOC06_RS26220	COG1388	LysM domain
FOC06_RS26220	COG3584	3D domain protein
FOC06_RS26225	COG1476	TRANSCRIPTIONal
FOC06_RS26240	COG3104	oligopeptide transport
FOC06_RS26245	COG1114	Component of the transport system for branched-chain amino acids
FOC06_RS26260	COG1113	amino acid transport
FOC06_RS26265	COG2252	PERMEase
FOC06_RS26290	COG0569	domain protein
FOC06_RS26290	COG0475	glutathione-regulated potassium exporter activity
FOC06_RS26305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC06_RS26310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC06_RS26315	COG0833	amino acid
FOC06_RS26320	COG4990	cell redox homeostasis
FOC06_RS26335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC06_RS26340	COG0697	spore germination
FOC06_RS26345	COG0531	amino acid
FOC06_RS26355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC06_RS26360	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC06_RS26365	COG1918	ferrous iron import across plasma membrane
FOC06_RS26365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC06_RS26370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC06_RS26375	COG0573	inorganic phosphate transmembrane transporter activity
FOC06_RS26380	COG0581	inorganic phosphate transmembrane transporter activity
FOC06_RS26390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC06_RS26505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC06_RS26525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC06_RS26530	COG1116	anion transmembrane transporter activity
FOC06_RS26535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC06_RS26540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC06_RS26545	COG0352	thiamine-phosphate diphosphorylase activity
FOC06_RS26550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC06_RS26555	COG2104	thiamine diphosphate biosynthetic process
FOC06_RS26565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC06_RS26570	COG0351	phosphomethylpyrimidine kinase
FOC06_RS26610	COG2205	protein histidine kinase activity
FOC06_RS26615	COG2814	Major facilitator Superfamily
FOC06_RS26620	COG1846	Transcriptional regulator
FOC06_RS26635	COG2252	PERMEase
FOC06_RS26640	COG1028	Short-chain dehydrogenase reductase Sdr
FOC06_RS26655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC06_RS26660	COG1621	beta-fructofuranosidase activity
FOC06_RS26665	COG1263	PTS System
FOC06_RS26665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC06_RS26670	COG1609	Transcriptional regulator
FOC06_RS26680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC06_RS26685	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC06_RS26720	COG0778	Nitroreductase
FOC06_RS26725	COG2719	SpoVR family
FOC06_RS26750	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC06_RS26755	COG1937	Protein conserved in bacteria
FOC06_RS26760	COG0425	Belongs to the sulfur carrier protein TusA family
FOC06_RS26760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC06_RS26765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC06_RS26765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC06_RS26770	COG0425	Belongs to the sulfur carrier protein TusA family
FOC06_RS26775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC06_RS26785	COG2210	Belongs to the sulfur carrier protein TusA family
FOC06_RS26790	COG0730	response to heat
FOC06_RS26800	COG1316	TRANSCRIPTIONal
FOC06_RS26805	COG0604	alcohol dehydrogenase
FOC06_RS26810	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC06_RS26825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC06_RS26825	COG3711	transcriptional antiterminator
FOC06_RS26830	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC06_RS26835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC06_RS26855	COG1388	LysM domain
FOC06_RS26855	COG3584	3D domain protein
FOC06_RS26860	COG0577	efflux transmembrane transporter activity
FOC06_RS26865	COG1136	(ABC) transporter
FOC06_RS26875	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC06_RS26890	COG1114	Component of the transport system for branched-chain amino acids
FOC06_RS26895	COG3546	catalase activity
FOC06_RS26930	COG0586	Pfam SNARE associated Golgi protein
FOC06_RS26960	COG0531	amino acid
FOC06_RS26965	COG0475	glutathione-regulated potassium exporter activity
FOC06_RS26975	COG1737	Transcriptional regulator
FOC06_RS26985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC06_RS26985	COG1263	PTS System
FOC06_RS26995	COG2259	Doxx family
FOC06_RS27010	COG0697	spore germination
FOC06_RS27015	COG1522	sequence-specific DNA binding
FOC06_RS27025	COG2814	Major facilitator Superfamily
FOC06_RS27030	COG1733	regulation of RNA biosynthetic process
FOC06_RS27040	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC06_RS27045	COG4533	DNA binding
FOC06_RS27050	COG2211	Major facilitator Superfamily