locus-tag	class	description
FOC08_RS00020	COG4695	Portal protein
FOC08_RS00045	COG4974	Belongs to the 'phage' integrase family
FOC08_RS00055	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC08_RS00060	COG0149	triose-phosphate isomerase activity
FOC08_RS00070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC08_RS00085	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC08_RS00110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC08_RS00125	COG2323	membrane
FOC08_RS00130	COG0740	serine-type endopeptidase activity
FOC08_RS00135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC08_RS00145	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC08_RS00155	COG1051	belongs to the nudix hydrolase family
FOC08_RS00165	COG0492	ferredoxin-NADP+ reductase activity
FOC08_RS00170	COG0457	Tetratricopeptide repeat
FOC08_RS00175	COG0110	maltose O-acetyltransferase activity
FOC08_RS00195	COG1950	PFAM Membrane protein of
FOC08_RS00205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC08_RS00210	COG0556	nucleotide-excision repair
FOC08_RS00230	COG0789	Transcriptional regulator
FOC08_RS00255	COG2855	membrane
FOC08_RS00260	COG0583	DNA-binding transcription factor activity
FOC08_RS00270	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC08_RS00285	COG1132	(ABC) transporter
FOC08_RS00290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC08_RS00295	COG3409	Peptidoglycan-binding domain 1 protein
FOC08_RS00295	COG0793	Belongs to the peptidase S41A family
FOC08_RS00300	COG2177	Part of the ABC transporter FtsEX involved in
FOC08_RS00305	COG2884	Cell division ATP-binding protein ftsE
FOC08_RS00325	COG0653	protein targeting
FOC08_RS00330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC08_RS00335	COG1278	Cold shock
FOC08_RS00340	COG1040	competence protein
FOC08_RS00345	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC08_RS00350	COG1388	LysM domain
FOC08_RS00350	COG0791	NLP P60 protein
FOC08_RS00355	COG1733	regulation of RNA biosynthetic process
FOC08_RS00360	COG1307	EDD domain protein, DegV family
FOC08_RS00365	COG1739	Uncharacterized protein family UPF0029
FOC08_RS00370	COG1316	TRANSCRIPTIONal
FOC08_RS00375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC08_RS00380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC08_RS00385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC08_RS00395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC08_RS00395	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC08_RS00410	COG3394	polysaccharide catabolic process
FOC08_RS00415	COG1486	melibiose metabolic process
FOC08_RS00420	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC08_RS00425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC08_RS00435	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC08_RS00440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC08_RS00445	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC08_RS00455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC08_RS00460	COG1301	dicarboxylic acid transport
FOC08_RS00470	COG0346	lactoylglutathione lyase activity
FOC08_RS00475	COG1511	domain protein
FOC08_RS00480	COG0583	DNA-binding transcription factor activity
FOC08_RS00485	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC08_RS00500	COG1271	oxidase subunit
FOC08_RS00505	COG1294	oxidase, subunit
FOC08_RS00510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC08_RS00520	COG1620	l-lactate permease
FOC08_RS00530	COG2389	metal-binding protein
FOC08_RS00540	COG1368	sulfuric ester hydrolase activity
FOC08_RS00555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS00570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC08_RS00575	COG3584	3D domain protein
FOC08_RS00575	COG1388	LysM domain
FOC08_RS00600	COG4715	Zinc finger, swim domain protein
FOC08_RS00605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC08_RS00635	COG1191	sigma factor activity
FOC08_RS00645	COG0577	efflux transmembrane transporter activity
FOC08_RS00650	COG1136	(ABC) transporter
FOC08_RS00685	COG5002	protein histidine kinase activity
FOC08_RS00690	COG0745	RESPONSE REGULATOR receiver
FOC08_RS00695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC08_RS00710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC08_RS00715	COG1134	teichoic acid transport
FOC08_RS00720	COG1682	transport, permease protein
FOC08_RS00725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC08_RS00770	COG1609	Transcriptional regulator
FOC08_RS00785	COG0739	heme binding
FOC08_RS00805	COG2385	sporulation resulting in formation of a cellular spore
FOC08_RS00810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC08_RS00820	COG4836	Membrane
FOC08_RS00825	COG1007	ATP synthesis coupled electron transport
FOC08_RS00830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC08_RS00835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC08_RS00845	COG0839	Belongs to the complex I subunit 6 family
FOC08_RS00860	COG0649	NAD binding
FOC08_RS00865	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC08_RS00875	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC08_RS00880	COG3300	MHYT domain
FOC08_RS00880	COG5001	Diguanylate cyclase
FOC08_RS00930	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC08_RS00965	COG0698	ribose 5-phosphate isomerase
FOC08_RS00975	COG2190	(PTS) system
FOC08_RS00980	COG2259	Doxx family
FOC08_RS00985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC08_RS01000	COG0009	L-threonylcarbamoyladenylate synthase
FOC08_RS01015	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC08_RS01020	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC08_RS01035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC08_RS01040	COG1494	fructose-1,6-bisphosphatase
FOC08_RS01045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC08_RS01060	COG4821	SIS domain
FOC08_RS01070	COG3343	RNA polymerase activity
FOC08_RS01080	COG1960	acyl-CoA dehydrogenase activity
FOC08_RS01085	COG1960	acyl-CoA dehydrogenase activity
FOC08_RS01090	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC08_RS01095	COG0183	Belongs to the thiolase family
FOC08_RS01100	COG2181	nitrate reductase activity
FOC08_RS01100	COG0247	lactate metabolic process
FOC08_RS01105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC08_RS01115	COG5001	Diguanylate cyclase
FOC08_RS01115	COG3300	MHYT domain
FOC08_RS01135	COG2197	response regulator
FOC08_RS01140	COG4585	Histidine kinase
FOC08_RS01145	COG0842	Transport permease protein
FOC08_RS01150	COG1131	(ABC) transporter
FOC08_RS01155	COG0024	Methionine aminopeptidase
FOC08_RS01165	COG2234	aminopeptidase activity
FOC08_RS01185	COG1595	DNA-templated transcription, initiation
FOC08_RS01190	COG0018	arginyl-trna synthetase
FOC08_RS01195	COG4506	Protein conserved in bacteria
FOC08_RS01200	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC08_RS01215	COG0010	Belongs to the arginase family
FOC08_RS01220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC08_RS01225	COG2814	Major facilitator Superfamily
FOC08_RS01230	COG0789	Transcriptional regulator
FOC08_RS01235	COG0584	glycerophosphoryl diester phosphodiesterase
FOC08_RS01240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC08_RS01250	COG1994	Peptidase M50
FOC08_RS01260	COG1078	dGTPase activity
FOC08_RS01265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS01270	COG1120	ATPase activity
FOC08_RS01275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS01300	COG0095	Lipoate-protein ligase
FOC08_RS01305	COG0280	phosphate acetyltransferase
FOC08_RS01320	COG3773	Cell wall hydrolase
FOC08_RS01330	COG2363	Small membrane protein
FOC08_RS01345	COG2233	PERMEase
FOC08_RS01350	COG0561	phosphatase activity
FOC08_RS01355	COG2814	Major facilitator Superfamily
FOC08_RS01365	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC08_RS01370	COG1131	(ABC) transporter
FOC08_RS01375	COG2755	lipolytic protein G-D-S-L family
FOC08_RS01380	COG1609	Transcriptional regulator
FOC08_RS01390	COG0460	homoserine dehydrogenase
FOC08_RS01410	COG1011	Hydrolase
FOC08_RS01415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC08_RS01425	COG2197	response regulator
FOC08_RS01435	COG0351	phosphomethylpyrimidine kinase
FOC08_RS01440	COG3706	GGDEF domain
FOC08_RS01445	COG2879	small protein
FOC08_RS01450	COG1966	Carbon starvation protein
FOC08_RS01455	COG3279	Response regulator of the LytR AlgR family
FOC08_RS01460	COG0477	Major facilitator Superfamily
FOC08_RS01485	COG0840	transmembrane signaling receptor activity
FOC08_RS01495	COG1607	acyl-coa hydrolase
FOC08_RS01510	COG0488	(ABC) transporter
FOC08_RS01530	COG0463	Glycosyl transferase, family 2
FOC08_RS01535	COG1309	transcriptional regulator
FOC08_RS01540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC08_RS01545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC08_RS01545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC08_RS01550	COG0628	permease
FOC08_RS01565	COG3279	Response regulator of the LytR AlgR family
FOC08_RS01570	COG3275	phosphorelay sensor kinase activity
FOC08_RS01575	COG2814	Major facilitator Superfamily
FOC08_RS01580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC08_RS01585	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC08_RS01590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC08_RS01610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC08_RS01615	COG1272	protein, Hemolysin III
FOC08_RS01635	COG0516	GMP reductase activity
FOC08_RS01640	COG1164	Oligoendopeptidase f
FOC08_RS01660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC08_RS01665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC08_RS01670	COG4853	Protein conserved in bacteria
FOC08_RS01675	COG4863	YycH protein
FOC08_RS01680	COG5002	protein histidine kinase activity
FOC08_RS01685	COG0745	RESPONSE REGULATOR receiver
FOC08_RS01715	COG0305	Participates in initiation and elongation during chromosome replication
FOC08_RS01725	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC08_RS01730	COG4241	membrane
FOC08_RS01740	COG0629	single-stranded DNA binding
FOC08_RS01750	COG0012	GTP binding
FOC08_RS01755	COG4481	Protein conserved in bacteria
FOC08_RS01760	COG0668	transmembrane transport
FOC08_RS01770	COG1475	DNA binding
FOC08_RS01775	COG1192	Involved in chromosome partitioning
FOC08_RS01795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC08_RS01800	COG1847	R3H domain protein
FOC08_RS01805	COG0706	membrane insertase activity
FOC08_RS01825	COG0592	DNA-directed DNA polymerase activity
FOC08_RS01830	COG2501	S4 domain
FOC08_RS01840	COG0187	DNA topoisomerase II activity
FOC08_RS01845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC08_RS01880	COG0516	GMP reductase activity
FOC08_RS01880	COG0517	IMP dehydrogenase activity
FOC08_RS01885	COG1686	Belongs to the peptidase S11 family
FOC08_RS01915	COG1428	Deoxynucleoside kinase
FOC08_RS01920	COG1428	Deoxynucleoside kinase
FOC08_RS01925	COG1335	isochorismatase
FOC08_RS01930	COG0590	tRNA wobble adenosine to inosine editing
FOC08_RS01940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC08_RS01995	COG1982	Orn Lys Arg decarboxylase major
FOC08_RS02005	COG0470	DNA polymerase III
FOC08_RS02010	COG1774	PSP1 C-terminal conserved region
FOC08_RS02020	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC08_RS02030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC08_RS02035	COG2002	toxin-antitoxin pair type II binding
FOC08_RS02040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC08_RS02040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC08_RS02045	COG0084	hydrolase, TatD family'
FOC08_RS02050	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC08_RS02065	COG4466	Protein conserved in bacteria
FOC08_RS02080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC08_RS02085	COG0251	oxidation-reduction process
FOC08_RS02100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC08_RS02105	COG0193	aminoacyl-tRNA hydrolase activity
FOC08_RS02115	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC08_RS02120	COG2002	toxin-antitoxin pair type II binding
FOC08_RS02125	COG2244	polysaccharide biosynthetic process
FOC08_RS02130	COG3956	TIGRFAM MazG family protein
FOC08_RS02135	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC08_RS02155	COG1098	S1 RNA binding domain
FOC08_RS02170	COG2208	phosphoserine phosphatase activity
FOC08_RS02175	COG0037	tRNA processing
FOC08_RS02185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC08_RS02200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC08_RS02205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC08_RS02210	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC08_RS02215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC08_RS02220	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC08_RS02225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC08_RS02230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC08_RS02235	COG1396	sequence-specific DNA binding
FOC08_RS02240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC08_RS02270	COG3880	PFAM UvrB UvrC protein
FOC08_RS02280	COG0542	response to heat
FOC08_RS02285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC08_RS02295	COG4956	integral membrane protein (PIN domain superfamily)
FOC08_RS02315	COG1045	serine acetyltransferase
FOC08_RS02330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC08_RS02335	COG3688	RNA-binding protein containing a PIN domain
FOC08_RS02345	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC08_RS02350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC08_RS02355	COG0250	Participates in transcription elongation, termination and antitermination
FOC08_RS02380	COG2813	Specifically methylates the guanine in position
FOC08_RS02390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC08_RS02395	COG1358	cellular component organization or biogenesis
FOC08_RS02500	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC08_RS02525	COG0201	protein transport
FOC08_RS02535	COG0024	Methionine aminopeptidase
FOC08_RS02545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC08_RS02575	COG1122	ATPase activity
FOC08_RS02580	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC08_RS02585	COG0101	tRNA pseudouridine synthase activity
FOC08_RS02605	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS02610	COG0489	protein tyrosine kinase activity
FOC08_RS02620	COG2194	sulfuric ester hydrolase activity
FOC08_RS02625	COG0726	polysaccharide deacetylase
FOC08_RS02705	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC08_RS02710	COG4856	YbbR-like protein
FOC08_RS02725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC08_RS02730	COG0596	Alpha beta hydrolase
FOC08_RS02750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC08_RS02755	COG0823	Involved in the tonB-independent uptake of proteins
FOC08_RS02755	COG4946	Tricorn protease homolog
FOC08_RS02755	COG1506	peptidase
FOC08_RS02790	COG2011	ABC-type metal ion transport system permease component
FOC08_RS02795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC08_RS02800	COG1464	Belongs to the NlpA lipoprotein family
FOC08_RS02815	COG0277	FAD linked oxidase domain protein
FOC08_RS02820	COG2271	Major facilitator Superfamily
FOC08_RS02830	COG2814	Major facilitator Superfamily
FOC08_RS02845	COG0601	transmembrane transport
FOC08_RS02850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC08_RS02855	COG0444	Belongs to the ABC transporter superfamily
FOC08_RS02860	COG4608	Belongs to the ABC transporter superfamily
FOC08_RS02865	COG4166	transmembrane transport
FOC08_RS02875	COG2207	Transcriptional regulator
FOC08_RS02890	COG4166	transmembrane transport
FOC08_RS02895	COG4166	transmembrane transport
FOC08_RS02900	COG0656	L-ascorbic acid biosynthetic process
FOC08_RS02905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC08_RS02915	COG4975	Glucose uptake
FOC08_RS02920	COG4149	molybdate abc transporter
FOC08_RS02930	COG1910	domain protein
FOC08_RS02940	COG0583	DNA-binding transcription factor activity
FOC08_RS02945	COG0697	spore germination
FOC08_RS02960	COG0204	Acyl-transferase
FOC08_RS02970	COG1609	Transcriptional regulator
FOC08_RS02980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS02990	COG0084	hydrolase, TatD family'
FOC08_RS02995	COG5298	Protein conserved in bacteria
FOC08_RS03015	COG0488	(ABC) transporter
FOC08_RS03030	COG0747	negative chemotaxis
FOC08_RS03035	COG0601	transmembrane transport
FOC08_RS03045	COG0444	Belongs to the ABC transporter superfamily
FOC08_RS03050	COG4608	Belongs to the ABC transporter superfamily
FOC08_RS03070	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC08_RS03075	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC08_RS03085	COG2814	Major facilitator Superfamily
FOC08_RS03095	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC08_RS03105	COG4294	response to UV
FOC08_RS03110	COG0457	Tetratricopeptide repeat
FOC08_RS03110	COG0705	Rhomboid family
FOC08_RS03120	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC08_RS03125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC08_RS03130	COG0864	Transcriptional regulator
FOC08_RS03135	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC08_RS03140	COG2183	response to ionizing radiation
FOC08_RS03235	COG0802	atpase or kinase
FOC08_RS03240	COG1214	PFAM Peptidase M22, glycoprotease
FOC08_RS03245	COG0456	acetyltransferase
FOC08_RS03250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC08_RS03255	COG0488	(ABC) transporter
FOC08_RS03270	COG1266	CAAX protease self-immunity
FOC08_RS03290	COG2252	PERMEase
FOC08_RS03300	COG5002	protein histidine kinase activity
FOC08_RS03330	COG2226	methyltransferase
FOC08_RS03370	COG1968	undecaprenyl-diphosphatase activity
FOC08_RS03385	COG2205	protein histidine kinase activity
FOC08_RS03390	COG0745	RESPONSE REGULATOR receiver
FOC08_RS03410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC08_RS03415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC08_RS03420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC08_RS03430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC08_RS03445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC08_RS03455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC08_RS03465	COG0151	Belongs to the GarS family
FOC08_RS03490	COG0210	DNA helicase
FOC08_RS03500	COG4851	CamS sex pheromone cAM373 precursor
FOC08_RS03515	COG1335	isochorismatase
FOC08_RS03520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC08_RS03525	COG2011	ABC-type metal ion transport system permease component
FOC08_RS03530	COG1464	Belongs to the NlpA lipoprotein family
FOC08_RS03550	COG1846	Transcriptional regulator
FOC08_RS03575	COG1597	lipid kinase activity
FOC08_RS03580	COG0546	phosphoglycolate phosphatase activity
FOC08_RS03585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC08_RS03595	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS03600	COG2076	Multidrug Resistance protein
FOC08_RS03605	COG2309	aminopeptidase activity
FOC08_RS03620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS03625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC08_RS03630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC08_RS03640	COG4807	Protein conserved in bacteria
FOC08_RS03670	COG1473	amidohydrolase
FOC08_RS03685	COG0450	alkyl hydroperoxide reductase
FOC08_RS03690	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC08_RS03700	COG0235	Class ii aldolase
FOC08_RS03705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS03710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS03715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS03730	COG0166	Belongs to the GPI family
FOC08_RS03765	COG5002	protein histidine kinase activity
FOC08_RS03785	COG3541	Predicted nucleotidyltransferase
FOC08_RS03790	COG2814	Major facilitator Superfamily
FOC08_RS03795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC08_RS03795	COG0723	plastoquinol--plastocyanin reductase activity
FOC08_RS03805	COG0765	amino acid transport
FOC08_RS03810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC08_RS03820	COG0840	transmembrane signaling receptor activity
FOC08_RS03825	COG0840	transmembrane signaling receptor activity
FOC08_RS03830	COG0366	Alpha amylase catalytic
FOC08_RS03835	COG1263	PTS System
FOC08_RS03835	COG2190	(PTS) system
FOC08_RS03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC08_RS03865	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC08_RS03880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC08_RS03890	COG1116	anion transmembrane transporter activity
FOC08_RS03895	COG0488	(ABC) transporter
FOC08_RS03940	COG2270	Major facilitator Superfamily
FOC08_RS03955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC08_RS03970	COG2310	stress, protein
FOC08_RS03975	COG2310	stress, protein
FOC08_RS03980	COG2310	stress, protein
FOC08_RS03985	COG0861	Integral membrane protein TerC family
FOC08_RS03995	COG3853	Toxic anion resistance protein (TelA)
FOC08_RS04010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC08_RS04020	COG1295	ribonuclease BN
FOC08_RS04025	COG2217	Heavy metal translocating P-type atpase
FOC08_RS04030	COG0697	spore germination
FOC08_RS04050	COG0586	Pfam SNARE associated Golgi protein
FOC08_RS04065	COG3871	stress protein (general stress protein 26)
FOC08_RS04070	COG0387	Pfam Sodium calcium exchanger
FOC08_RS04080	COG0535	radical SAM domain protein
FOC08_RS04105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC08_RS04110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC08_RS04115	COG0582	viral genome integration into host DNA
FOC08_RS04120	COG1396	sequence-specific DNA binding
FOC08_RS04135	COG1396	sequence-specific DNA binding
FOC08_RS04170	COG1484	DNA-dependent DNA replication
FOC08_RS04255	COG0582	viral genome integration into host DNA
FOC08_RS04260	COG0582	viral genome integration into host DNA
FOC08_RS04380	COG0101	tRNA pseudouridine synthase activity
FOC08_RS04390	COG3829	transcription factor binding
FOC08_RS04400	COG0833	amino acid
FOC08_RS04405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC08_RS04425	COG2066	Belongs to the glutaminase family
FOC08_RS04430	COG1263	PTS System
FOC08_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC08_RS04435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC08_RS04450	COG0463	Glycosyl transferase, family 2
FOC08_RS04465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC08_RS04465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC08_RS04485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC08_RS04505	COG1228	amidohydrolase
FOC08_RS04510	COG1090	epimerase
FOC08_RS04540	COG1988	membrane-bound metal-dependent
FOC08_RS04545	COG1194	a g-specific adenine glycosylase
FOC08_RS04570	COG1132	(ABC) transporter
FOC08_RS04575	COG4129	membrane
FOC08_RS04580	COG0067	glutamate synthase
FOC08_RS04580	COG0070	glutamate synthase
FOC08_RS04580	COG0069	glutamate synthase activity
FOC08_RS04590	COG4555	ABC transporter
FOC08_RS04610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC08_RS04615	COG0735	belongs to the Fur family
FOC08_RS04730	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC08_RS04735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC08_RS04745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC08_RS04755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC08_RS04765	COG2766	serine protein kinase
FOC08_RS04785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC08_RS04795	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC08_RS04800	COG2268	Band 7 protein
FOC08_RS04810	COG3290	protein histidine kinase activity
FOC08_RS04820	COG2851	Citrate transporter
FOC08_RS04840	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC08_RS04845	COG3842	ATPase activity
FOC08_RS04850	COG1175	transmembrane transport
FOC08_RS04855	COG0395	ABC-type sugar transport system, permease component
FOC08_RS04865	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC08_RS04870	COG0745	RESPONSE REGULATOR receiver
FOC08_RS04875	COG5002	protein histidine kinase activity
FOC08_RS04885	COG4990	cell redox homeostasis
FOC08_RS04895	COG3290	protein histidine kinase activity
FOC08_RS04900	COG4565	transcriptional regulatory protein
FOC08_RS04905	COG3493	citrate carrier protein
FOC08_RS04910	COG0281	malic enzyme
FOC08_RS04925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS04935	COG5002	protein histidine kinase activity
FOC08_RS04940	COG0745	RESPONSE REGULATOR receiver
FOC08_RS04945	COG0456	acetyltransferase
FOC08_RS04945	COG0454	-acetyltransferase
FOC08_RS04950	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC08_RS04955	COG3383	formate dehydrogenase (NAD+) activity
FOC08_RS04960	COG2427	Protein of unknown function (DUF1641)
FOC08_RS04975	COG0531	amino acid
FOC08_RS04980	COG0640	Transcriptional regulator
FOC08_RS04985	COG2217	Heavy metal translocating P-type atpase
FOC08_RS04990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC08_RS05005	COG3227	Zinc metalloprotease (Elastase)
FOC08_RS05025	COG2720	vancomycin resistance protein
FOC08_RS05030	COG1316	TRANSCRIPTIONal
FOC08_RS05035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS05040	COG0346	lactoylglutathione lyase activity
FOC08_RS05045	COG1253	flavin adenine dinucleotide binding
FOC08_RS05050	COG1027	Aspartate ammonia-lyase
FOC08_RS05055	COG1620	l-lactate permease
FOC08_RS05070	COG3104	oligopeptide transport
FOC08_RS05075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS05080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS05085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS05095	COG2226	methyltransferase
FOC08_RS05100	COG0156	8-amino-7-oxononanoate synthase activity
FOC08_RS05105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC08_RS05115	COG4548	von Willebrand factor, type A
FOC08_RS05120	COG0714	Associated with various cellular activities
FOC08_RS05125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC08_RS05145	COG0531	amino acid
FOC08_RS05150	COG2188	Transcriptional regulator
FOC08_RS05155	COG1263	PTS System
FOC08_RS05155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC08_RS05160	COG0366	Alpha amylase catalytic
FOC08_RS05175	COG0697	spore germination
FOC08_RS05185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC08_RS05190	COG1115	amino acid carrier protein
FOC08_RS05195	COG1126	abc transporter atp-binding protein
FOC08_RS05200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC08_RS05205	COG0765	amino acid transport
FOC08_RS05210	COG0765	amino acid transport
FOC08_RS05215	COG0833	amino acid
FOC08_RS05240	COG2378	regulation of single-species biofilm formation
FOC08_RS05245	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC08_RS05250	COG5002	protein histidine kinase activity
FOC08_RS05265	COG0659	secondary active sulfate transmembrane transporter activity
FOC08_RS05280	COG0747	negative chemotaxis
FOC08_RS05290	COG0601	transmembrane transport
FOC08_RS05295	COG4608	Belongs to the ABC transporter superfamily
FOC08_RS05305	COG2271	Major facilitator Superfamily
FOC08_RS05310	COG1846	Transcriptional regulator
FOC08_RS05320	COG1609	Transcriptional regulator
FOC08_RS05325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC08_RS05335	COG1129	ABC transporter
FOC08_RS05340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC08_RS05345	COG1879	ABC-type sugar transport system periplasmic component
FOC08_RS05350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC08_RS05370	COG1063	alcohol dehydrogenase
FOC08_RS05385	COG3568	Endonuclease Exonuclease Phosphatase
FOC08_RS05410	COG1968	undecaprenyl-diphosphatase activity
FOC08_RS05415	COG0840	transmembrane signaling receptor activity
FOC08_RS05420	COG3584	3D domain protein
FOC08_RS05420	COG1388	LysM domain
FOC08_RS05425	COG1476	TRANSCRIPTIONal
FOC08_RS05440	COG3104	oligopeptide transport
FOC08_RS05445	COG1114	Component of the transport system for branched-chain amino acids
FOC08_RS05460	COG1113	amino acid transport
FOC08_RS05465	COG2252	PERMEase
FOC08_RS05490	COG0569	domain protein
FOC08_RS05490	COG0475	glutathione-regulated potassium exporter activity
FOC08_RS05505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC08_RS05510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC08_RS05515	COG0833	amino acid
FOC08_RS05520	COG4990	cell redox homeostasis
FOC08_RS05535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC08_RS05540	COG0697	spore germination
FOC08_RS05545	COG0531	amino acid
FOC08_RS05555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC08_RS05560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC08_RS05565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC08_RS05565	COG1918	ferrous iron import across plasma membrane
FOC08_RS05570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC08_RS05575	COG0573	inorganic phosphate transmembrane transporter activity
FOC08_RS05580	COG0581	inorganic phosphate transmembrane transporter activity
FOC08_RS05590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC08_RS05705	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC08_RS05725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC08_RS05730	COG1116	anion transmembrane transporter activity
FOC08_RS05735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC08_RS05740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC08_RS05745	COG0352	thiamine-phosphate diphosphorylase activity
FOC08_RS05750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC08_RS05755	COG2104	thiamine diphosphate biosynthetic process
FOC08_RS05765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC08_RS05770	COG0351	phosphomethylpyrimidine kinase
FOC08_RS05810	COG2205	protein histidine kinase activity
FOC08_RS05815	COG2814	Major facilitator Superfamily
FOC08_RS05820	COG1846	Transcriptional regulator
FOC08_RS05835	COG2252	PERMEase
FOC08_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS05855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC08_RS05860	COG1621	beta-fructofuranosidase activity
FOC08_RS05865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC08_RS05865	COG1263	PTS System
FOC08_RS05870	COG1609	Transcriptional regulator
FOC08_RS05880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC08_RS05885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC08_RS05920	COG0778	Nitroreductase
FOC08_RS05925	COG2719	SpoVR family
FOC08_RS05950	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC08_RS05955	COG1937	Protein conserved in bacteria
FOC08_RS05960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC08_RS05960	COG0425	Belongs to the sulfur carrier protein TusA family
FOC08_RS05965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS05965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC08_RS05970	COG0425	Belongs to the sulfur carrier protein TusA family
FOC08_RS05975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC08_RS05985	COG2210	Belongs to the sulfur carrier protein TusA family
FOC08_RS05990	COG0730	response to heat
FOC08_RS06000	COG1316	TRANSCRIPTIONal
FOC08_RS06005	COG0604	alcohol dehydrogenase
FOC08_RS06010	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC08_RS06025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC08_RS06025	COG3711	transcriptional antiterminator
FOC08_RS06030	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC08_RS06035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC08_RS06055	COG3584	3D domain protein
FOC08_RS06055	COG1388	LysM domain
FOC08_RS06060	COG0577	efflux transmembrane transporter activity
FOC08_RS06065	COG1136	(ABC) transporter
FOC08_RS06075	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC08_RS06090	COG1114	Component of the transport system for branched-chain amino acids
FOC08_RS06095	COG3546	catalase activity
FOC08_RS06130	COG0586	Pfam SNARE associated Golgi protein
FOC08_RS06160	COG0531	amino acid
FOC08_RS06165	COG0475	glutathione-regulated potassium exporter activity
FOC08_RS06175	COG1737	Transcriptional regulator
FOC08_RS06185	COG1263	PTS System
FOC08_RS06185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC08_RS06195	COG2259	Doxx family
FOC08_RS06210	COG0697	spore germination
FOC08_RS06215	COG1522	sequence-specific DNA binding
FOC08_RS06225	COG2076	Multidrug Resistance protein
FOC08_RS06230	COG2076	Multidrug Resistance protein
FOC08_RS06235	COG1309	transcriptional regulator
FOC08_RS06240	COG2814	Major facilitator Superfamily
FOC08_RS06245	COG1733	regulation of RNA biosynthetic process
FOC08_RS06255	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC08_RS06260	COG4533	DNA binding
FOC08_RS06265	COG2211	Major facilitator Superfamily
FOC08_RS06275	COG0693	protein deglycase activity
FOC08_RS06280	COG0753	catalase activity
FOC08_RS06280	COG0693	protein deglycase activity
FOC08_RS06290	COG0531	amino acid
FOC08_RS06295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC08_RS06305	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS06310	COG1132	(ABC) transporter
FOC08_RS06320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC08_RS06325	COG0765	amino acid transport
FOC08_RS06330	COG1126	abc transporter atp-binding protein
FOC08_RS06345	COG0189	ligase activity
FOC08_RS06375	COG0028	Belongs to the TPP enzyme family
FOC08_RS06380	COG3527	Alpha-acetolactate decarboxylase
FOC08_RS06395	COG0561	phosphatase activity
FOC08_RS06410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC08_RS06425	COG0659	secondary active sulfate transmembrane transporter activity
FOC08_RS06445	COG0653	protein targeting
FOC08_RS06450	COG2244	polysaccharide biosynthetic process
FOC08_RS06460	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS06465	COG4196	transglutaminase domain protein
FOC08_RS06480	COG1696	Membrane protein involved in D-alanine export
FOC08_RS06495	COG1024	Enoyl-CoA hydratase
FOC08_RS06515	COG1363	Peptidase, m42
FOC08_RS06535	COG3938	Belongs to the proline racemase family
FOC08_RS06570	COG0601	transmembrane transport
FOC08_RS06575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC08_RS06585	COG4608	Belongs to the ABC transporter superfamily
FOC08_RS06590	COG0322	excinuclease ABC activity
FOC08_RS06620	COG0477	Major facilitator Superfamily
FOC08_RS06625	COG3290	protein histidine kinase activity
FOC08_RS06630	COG4565	transcriptional regulatory protein
FOC08_RS06635	COG3181	Tripartite tricarboxylate transporter family receptor
FOC08_RS06665	COG4978	Transcriptional regulator
FOC08_RS06665	COG0789	Transcriptional regulator
FOC08_RS06680	COG0305	Participates in initiation and elongation during chromosome replication
FOC08_RS06710	COG0477	Major facilitator Superfamily
FOC08_RS06755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC08_RS06755	COG3320	Male sterility
FOC08_RS06780	COG1183	phosphatidylcholine synthase activity
FOC08_RS06800	COG2376	Dihydroxyacetone kinase
FOC08_RS06810	COG2376	Dihydroxyacetone kinase
FOC08_RS06815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC08_RS06820	COG1959	2 iron, 2 sulfur cluster binding
FOC08_RS06850	COG3437	response regulator, receiver
FOC08_RS06850	COG2770	Histidine kinase
FOC08_RS06900	COG3237	CsbD-like
FOC08_RS06925	COG1191	sigma factor activity
FOC08_RS06935	COG2208	phosphoserine phosphatase activity
FOC08_RS06940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC08_RS06945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC08_RS06945	COG0784	Response regulator, receiver
FOC08_RS06945	COG2198	Histidine kinase
FOC08_RS06945	COG2205	protein histidine kinase activity
FOC08_RS06965	COG0393	Putative heavy-metal-binding
FOC08_RS06995	COG0420	3'-5' exonuclease activity
FOC08_RS07020	COG1309	transcriptional regulator
FOC08_RS07025	COG2814	Major facilitator Superfamily
FOC08_RS07030	COG0346	lactoylglutathione lyase activity
FOC08_RS07035	COG0346	lactoylglutathione lyase activity
FOC08_RS07040	COG0457	Tetratricopeptide repeat
FOC08_RS07045	COG2267	carboxylic ester hydrolase activity
FOC08_RS07065	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC08_RS07070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC08_RS07080	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC08_RS07115	COG0477	Major facilitator Superfamily
FOC08_RS07120	COG0477	Major facilitator Superfamily
FOC08_RS07130	COG3973	AAA domain
FOC08_RS07135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC08_RS07155	COG4980	gas vesicle protein
FOC08_RS07160	COG0537	adenosine 5'-monophosphoramidase activity
FOC08_RS07165	COG1131	(ABC) transporter
FOC08_RS07170	COG4473	ABC transporter
FOC08_RS07185	COG1309	transcriptional regulator
FOC08_RS07190	COG3402	PFAM membrane-flanked domain
FOC08_RS07235	COG3402	PFAM membrane-flanked domain
FOC08_RS07240	COG3428	Bacterial PH domain
FOC08_RS07245	COG2329	Antibiotic biosynthesis monooxygenase
FOC08_RS07250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC08_RS07255	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC08_RS07300	COG1309	transcriptional regulator
FOC08_RS07305	COG1511	domain protein
FOC08_RS07330	COG1609	Transcriptional regulator
FOC08_RS07340	COG1234	tRNA 3'-trailer cleavage
FOC08_RS07345	COG0095	Lipoate-protein ligase
FOC08_RS07355	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS07385	COG3209	COG3209 Rhs family protein
FOC08_RS07420	COG1078	dGTPase activity
FOC08_RS07430	COG1595	DNA-templated transcription, initiation
FOC08_RS07435	COG3708	Transcriptional regulator
FOC08_RS07435	COG2207	Transcriptional regulator
FOC08_RS07445	COG2205	protein histidine kinase activity
FOC08_RS07450	COG0745	RESPONSE REGULATOR receiver
FOC08_RS07475	COG0501	Belongs to the peptidase M48B family
FOC08_RS07480	COG0840	transmembrane signaling receptor activity
FOC08_RS07485	COG0697	spore germination
FOC08_RS07500	COG0497	DNA recombination
FOC08_RS07505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC08_RS07510	COG2224	Isocitrate lyase
FOC08_RS07520	COG1278	Cold shock
FOC08_RS07535	COG4903	ComK protein
FOC08_RS07540	COG0398	Pfam SNARE associated Golgi protein
FOC08_RS07550	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC08_RS07555	COG1074	ATP-dependent DNA helicase activity
FOC08_RS07600	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC08_RS07625	COG0367	asparagine synthase
FOC08_RS07635	COG0753	catalase activity
FOC08_RS07660	COG2996	Protein conserved in bacteria
FOC08_RS07670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC08_RS07680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS07695	COG0561	phosphatase activity
FOC08_RS07705	COG0542	response to heat
FOC08_RS07715	COG2267	carboxylic ester hydrolase activity
FOC08_RS07730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC08_RS07735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC08_RS07740	COG5504	Zn-dependent protease
FOC08_RS07750	COG0180	Tryptophanyl-tRNA synthetase
FOC08_RS07760	COG4166	transmembrane transport
FOC08_RS07765	COG0601	transmembrane transport
FOC08_RS07770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC08_RS07775	COG0444	Belongs to the ABC transporter superfamily
FOC08_RS07780	COG4608	Belongs to the ABC transporter superfamily
FOC08_RS07785	COG0534	Mate efflux family protein
FOC08_RS07790	COG4166	transmembrane transport
FOC08_RS07800	COG1393	Belongs to the ArsC family
FOC08_RS07805	COG0861	Integral membrane protein TerC family
FOC08_RS07810	COG4862	establishment of competence for transformation
FOC08_RS07815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC08_RS07825	COG1164	Oligoendopeptidase f
FOC08_RS07835	COG2346	COG2346, Truncated hemoglobins
FOC08_RS07840	COG4116	CYTH
FOC08_RS07850	COG2357	RelA SpoT domain protein
FOC08_RS07855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC08_RS07860	COG0564	pseudouridine synthase activity
FOC08_RS07880	COG1216	Glycosyl transferase, family 2
FOC08_RS07900	COG0463	Glycosyl transferase, family 2
FOC08_RS07900	COG0457	Tetratricopeptide repeat
FOC08_RS07920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC08_RS07935	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC08_RS07980	COG2153	protein acetylation
FOC08_RS07985	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC08_RS07990	COG2382	esterase
FOC08_RS08005	COG5492	domain, Protein
FOC08_RS08010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC08_RS08020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC08_RS08020	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC08_RS08055	COG1620	l-lactate permease
FOC08_RS08060	COG5634	Uncharacterized conserved protein (DUF2278)
FOC08_RS08115	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC08_RS08125	COG1476	TRANSCRIPTIONal
FOC08_RS08185	COG2226	methyltransferase
FOC08_RS08195	COG1686	Belongs to the peptidase S11 family
FOC08_RS08200	COG0681	Belongs to the peptidase S26 family
FOC08_RS08235	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS08240	COG3842	ATPase activity
FOC08_RS08245	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC08_RS08250	COG1177	transmembrane transport
FOC08_RS08255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC08_RS08265	COG2409	Drug exporters of the RND superfamily
FOC08_RS08275	COG0564	pseudouridine synthase activity
FOC08_RS08285	COG2340	Cysteine-rich secretory protein family
FOC08_RS08290	COG0247	lactate metabolic process
FOC08_RS08295	COG0277	FAD linked oxidase domain protein
FOC08_RS08300	COG3835	regulator
FOC08_RS08310	COG0745	RESPONSE REGULATOR receiver
FOC08_RS08315	COG5002	protein histidine kinase activity
FOC08_RS08320	COG2186	Transcriptional regulator
FOC08_RS08340	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC08_RS08350	COG2116	formate transmembrane transporter activity
FOC08_RS08355	COG0861	Integral membrane protein TerC family
FOC08_RS08360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC08_RS08370	COG2030	dehydratase
FOC08_RS08390	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS08395	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC08_RS08405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC08_RS08415	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC08_RS08430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC08_RS08445	COG1349	DNA-binding transcription factor activity
FOC08_RS08465	COG2861	carbohydrate metabolic process
FOC08_RS08475	COG3852	Histidine kinase
FOC08_RS08480	COG1846	Transcriptional regulator
FOC08_RS08490	COG2318	DinB family
FOC08_RS08495	COG5002	protein histidine kinase activity
FOC08_RS08505	COG0720	synthase
FOC08_RS08520	COG4873	Protein conserved in bacteria
FOC08_RS08545	COG1780	Probably involved in ribonucleotide reductase function
FOC08_RS08565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC08_RS08570	COG1725	Transcriptional regulator
FOC08_RS08575	COG1131	(ABC) transporter
FOC08_RS08585	COG1131	(ABC) transporter
FOC08_RS08590	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC08_RS08605	COG1522	sequence-specific DNA binding
FOC08_RS08615	COG1335	isochorismatase
FOC08_RS08625	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC08_RS08630	COG2070	2-Nitropropane dioxygenase
FOC08_RS08635	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC08_RS08645	COG1696	Membrane protein involved in D-alanine export
FOC08_RS08665	COG0716	FMN binding
FOC08_RS08675	COG3173	Aminoglycoside phosphotransferase
FOC08_RS08690	COG0534	Mate efflux family protein
FOC08_RS08695	COG1968	undecaprenyl-diphosphatase activity
FOC08_RS08710	COG1846	Transcriptional regulator
FOC08_RS08720	COG1301	dicarboxylic acid transport
FOC08_RS08725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC08_RS08730	COG4709	membrane
FOC08_RS08735	COG3874	Sporulation protein YtfJ
FOC08_RS08760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC08_RS08765	COG0028	Belongs to the TPP enzyme family
FOC08_RS08770	COG0440	acetolactate synthase activity
FOC08_RS08775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC08_RS08785	COG0473	3-isopropylmalate dehydrogenase activity
FOC08_RS08810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC08_RS08845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC08_RS08860	COG1183	phosphatidylcholine synthase activity
FOC08_RS08865	COG1368	sulfuric ester hydrolase activity
FOC08_RS08875	COG0019	diaminopimelate decarboxylase activity
FOC08_RS08895	COG0529	Catalyzes the synthesis of activated sulfate
FOC08_RS08900	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC08_RS08920	COG1648	precorrin-2 dehydrogenase activity
FOC08_RS08925	COG0733	neurotransmitter:sodium symporter activity
FOC08_RS08945	COG1757	Na H antiporter
FOC08_RS08960	COG4758	membrane
FOC08_RS08965	COG4585	Histidine kinase
FOC08_RS08970	COG2197	response regulator
FOC08_RS08980	COG1114	Component of the transport system for branched-chain amino acids
FOC08_RS08990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC08_RS09015	COG1017	nitric oxide dioxygenase activity
FOC08_RS09015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC08_RS09030	COG0730	response to heat
FOC08_RS09035	COG0306	phosphate transporter
FOC08_RS09040	COG1392	Phosphate transport regulator
FOC08_RS09045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC08_RS09065	COG1801	Protein of unknown function DUF72
FOC08_RS09075	COG0582	viral genome integration into host DNA
FOC08_RS09080	COG5002	protein histidine kinase activity
FOC08_RS09100	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC08_RS09100	COG0392	lysyltransferase activity
FOC08_RS09115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC08_RS09120	COG1686	Belongs to the peptidase S11 family
FOC08_RS09125	COG2715	membrane protein required for spore maturation
FOC08_RS09130	COG0700	Nucleoside recognition
FOC08_RS09135	COG1187	pseudouridine synthase activity
FOC08_RS09145	COG1333	cytochrome c biogenesis protein
FOC08_RS09150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC08_RS09155	COG0745	RESPONSE REGULATOR receiver
FOC08_RS09160	COG5002	protein histidine kinase activity
FOC08_RS09165	COG2096	Adenosyltransferase
FOC08_RS09180	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC08_RS09185	COG1141	Ferredoxin
FOC08_RS09190	COG4955	Helix-turn-helix domain
FOC08_RS09195	COG0514	ATP-dependent DNA helicase (RecQ)
FOC08_RS09200	COG1266	CAAX protease self-immunity
FOC08_RS09220	COG4862	establishment of competence for transformation
FOC08_RS09225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC08_RS09245	COG0492	ferredoxin-NADP+ reductase activity
FOC08_RS09320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC08_RS09335	COG0142	geranyltranstransferase activity
FOC08_RS09345	COG0142	geranyltranstransferase activity
FOC08_RS09350	COG0105	UTP biosynthetic process
FOC08_RS09365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC08_RS09370	COG0457	Tetratricopeptide repeat
FOC08_RS09390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC08_RS09400	COG4347	Protein of unknown function (DUF1405)
FOC08_RS09415	COG2738	Putative neutral zinc metallopeptidase
FOC08_RS09425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS09430	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC08_RS09445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC08_RS09450	COG0438	transferase activity, transferring glycosyl groups
FOC08_RS09485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC08_RS09485	COG1199	ATP-dependent helicase activity
FOC08_RS09505	COG3935	DnaD domain protein
FOC08_RS09510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC08_RS09520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC08_RS09520	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC08_RS09560	COG4474	Belongs to the UPF0398 family
FOC08_RS09575	COG0116	Belongs to the methyltransferase superfamily
FOC08_RS09585	COG1199	ATP-dependent helicase activity
FOC08_RS09590	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC08_RS09600	COG3173	Aminoglycoside phosphotransferase
FOC08_RS09605	COG0024	Methionine aminopeptidase
FOC08_RS09620	COG2233	PERMEase
FOC08_RS09625	COG2311	Membrane
FOC08_RS09630	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC08_RS09640	COG0456	acetyltransferase
FOC08_RS09690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC08_RS09715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC08_RS09730	COG1215	transferase activity, transferring glycosyl groups
FOC08_RS09750	COG0454	-acetyltransferase
FOC08_RS09770	COG0328	RNA-DNA hybrid ribonuclease activity
FOC08_RS09810	COG1280	lysine exporter protein (LysE YggA)
FOC08_RS09825	COG3162	membrane
FOC08_RS09830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC08_RS09835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC08_RS09845	COG0475	glutathione-regulated potassium exporter activity
FOC08_RS09855	COG4978	Transcriptional regulator
FOC08_RS09855	COG0789	Transcriptional regulator
FOC08_RS09865	COG2323	membrane
FOC08_RS09870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC08_RS09925	COG1923	regulation of RNA biosynthetic process
FOC08_RS09935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC08_RS09940	COG1360	Flagellar Motor Protein
FOC08_RS09945	COG2201	protein-glutamate methylesterase activity
FOC08_RS09955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC08_RS09955	COG1776	CheC inhibitor of MCP methylation
FOC08_RS09970	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC08_RS09990	COG1256	bacterial-type flagellum assembly
FOC08_RS10015	COG1815	bacterial-type flagellum-dependent cell motility
FOC08_RS10020	COG1558	bacterial-type flagellum-dependent cell motility
FOC08_RS10025	COG1677	Flagellar hook-basal body complex protein FliE
FOC08_RS10035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC08_RS10045	COG1157	protein secretion by the type III secretion system
FOC08_RS10095	COG0463	Glycosyl transferase, family 2
FOC08_RS10130	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC08_RS10135	COG0741	lytic transglycosylase activity
FOC08_RS10150	COG1776	CheC inhibitor of MCP methylation
FOC08_RS10150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC08_RS10160	COG1338	Plays a role in the flagellum-specific transport system
FOC08_RS10165	COG1987	bacterial-type flagellum assembly
FOC08_RS10175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC08_RS10180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC08_RS10190	COG4786	Flagellar basal body rod
FOC08_RS10195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC08_RS10220	COG1309	transcriptional regulator
FOC08_RS10240	COG2329	Antibiotic biosynthesis monooxygenase
FOC08_RS10270	COG3842	ATPase activity
FOC08_RS10275	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC08_RS10280	COG1177	transmembrane transport
FOC08_RS10285	COG1234	tRNA 3'-trailer cleavage
FOC08_RS10315	COG1686	Belongs to the peptidase S11 family
FOC08_RS10325	COG0406	alpha-ribazole phosphatase activity
FOC08_RS10355	COG0367	asparagine synthase
FOC08_RS10385	COG1802	Transcriptional regulator
FOC08_RS10390	COG0697	spore germination
FOC08_RS10395	COG0523	cobalamin synthesis protein
FOC08_RS10400	COG0701	Predicted permease
FOC08_RS10410	COG0438	transferase activity, transferring glycosyl groups
FOC08_RS10410	COG1216	Glycosyl transferase, family 2
FOC08_RS10415	COG1757	Na H antiporter
FOC08_RS10420	COG0114	fumarate hydratase activity
FOC08_RS10445	COG3340	Belongs to the peptidase S51 family
FOC08_RS10465	COG0785	Cytochrome C biogenesis protein
FOC08_RS10495	COG2733	membrane
FOC08_RS10530	COG1131	(ABC) transporter
FOC08_RS10545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC08_RS10550	COG0528	UMP kinase activity
FOC08_RS10560	COG1027	Aspartate ammonia-lyase
FOC08_RS10565	COG0281	malic enzyme
FOC08_RS10570	COG4191	Histidine kinase
FOC08_RS10575	COG0784	Response regulator, receiver
FOC08_RS10580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC08_RS10630	COG1051	belongs to the nudix hydrolase family
FOC08_RS10635	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS10660	COG1966	Carbon starvation protein
FOC08_RS10675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC08_RS10685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC08_RS10695	COG2223	nitrite transmembrane transporter activity
FOC08_RS10700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC08_RS10715	COG2244	polysaccharide biosynthetic process
FOC08_RS10720	COG0733	neurotransmitter:sodium symporter activity
FOC08_RS10730	COG5566	PFAM Mor transcription activator
FOC08_RS10735	COG2323	membrane
FOC08_RS10750	COG2084	Dehydrogenase
FOC08_RS10765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC08_RS10775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC08_RS10780	COG0028	Belongs to the TPP enzyme family
FOC08_RS10785	COG0440	acetolactate synthase activity
FOC08_RS10790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC08_RS10800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC08_RS10825	COG2814	Major facilitator Superfamily
FOC08_RS10830	COG3384	dioxygenase
FOC08_RS10840	COG3279	Response regulator of the LytR AlgR family
FOC08_RS10845	COG0427	acetyl-CoA hydrolase
FOC08_RS10865	COG1073	alpha beta
FOC08_RS10900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS10920	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC08_RS10935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC08_RS10965	COG2390	Transcriptional regulator
FOC08_RS10975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS10980	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC08_RS10995	COG4224	UPF0291 protein
FOC08_RS11015	COG0006	proline dipeptidase activity
FOC08_RS11020	COG2132	Multicopper oxidase
FOC08_RS11050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC08_RS11065	COG1276	copper resistance
FOC08_RS11065	COG2372	response to copper ion
FOC08_RS11070	COG4549	nuclear export factor GLE1
FOC08_RS11080	COG0697	spore germination
FOC08_RS11085	COG0583	DNA-binding transcription factor activity
FOC08_RS11090	COG1959	2 iron, 2 sulfur cluster binding
FOC08_RS11095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC08_RS11100	COG0778	Nitroreductase
FOC08_RS11110	COG0628	permease
FOC08_RS11115	COG0039	L-malate dehydrogenase activity
FOC08_RS11120	COG1231	oxidoreductase activity
FOC08_RS11125	COG0523	cobalamin synthesis protein
FOC08_RS11140	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS11145	COG2030	dehydratase
FOC08_RS11150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC08_RS11160	COG0411	ABC transporter
FOC08_RS11180	COG0583	DNA-binding transcription factor activity
FOC08_RS11200	COG1846	Transcriptional regulator
FOC08_RS11210	COG1271	oxidase subunit
FOC08_RS11215	COG1294	oxidase, subunit
FOC08_RS11220	COG4988	ABC transporter
FOC08_RS11225	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC08_RS11245	COG1686	Belongs to the peptidase S11 family
FOC08_RS11260	COG1388	LysM domain
FOC08_RS11260	COG0791	NLP P60 protein
FOC08_RS11275	COG0745	RESPONSE REGULATOR receiver
FOC08_RS11280	COG5002	protein histidine kinase activity
FOC08_RS11290	COG0300	oxidoreductase activity
FOC08_RS11305	COG0726	polysaccharide deacetylase
FOC08_RS11325	COG0460	homoserine dehydrogenase
FOC08_RS11350	COG1316	TRANSCRIPTIONal
FOC08_RS11360	COG0745	RESPONSE REGULATOR receiver
FOC08_RS11365	COG5002	protein histidine kinase activity
FOC08_RS11370	COG0726	polysaccharide deacetylase
FOC08_RS11380	COG1285	pathogenesis
FOC08_RS11385	COG1247	-acetyltransferase
FOC08_RS11395	COG4264	IucA IucC family
FOC08_RS11400	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS11415	COG1082	Xylose isomerase domain protein TIM barrel
FOC08_RS11430	COG1279	arginine transmembrane transporter activity
FOC08_RS11440	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC08_RS11480	COG2002	toxin-antitoxin pair type II binding
FOC08_RS11485	COG1404	Belongs to the peptidase S8 family
FOC08_RS11490	COG0640	Transcriptional regulator
FOC08_RS11495	COG0667	Aldo Keto reductase
FOC08_RS11500	COG2814	Major facilitator Superfamily
FOC08_RS11525	COG0840	transmembrane signaling receptor activity
FOC08_RS11540	COG3949	Membrane
FOC08_RS11545	COG0783	Belongs to the Dps family
FOC08_RS11560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC08_RS11570	COG1231	oxidoreductase activity
FOC08_RS11580	COG4989	oxidoreductase activity
FOC08_RS11585	COG0523	cobalamin synthesis protein
FOC08_RS11590	COG0456	acetyltransferase
FOC08_RS11640	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC08_RS11640	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC08_RS11645	COG0702	epimerase
FOC08_RS11655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC08_RS11665	COG4166	transmembrane transport
FOC08_RS11680	COG0406	alpha-ribazole phosphatase activity
FOC08_RS11690	COG5337	Spore coat protein CotH
FOC08_RS11695	COG1051	belongs to the nudix hydrolase family
FOC08_RS11700	COG0586	Pfam SNARE associated Golgi protein
FOC08_RS11705	COG2244	polysaccharide biosynthetic process
FOC08_RS11715	COG0701	Predicted permease
FOC08_RS11720	COG3689	TIGRFAM TIGR03943 family protein
FOC08_RS11725	COG1607	acyl-coa hydrolase
FOC08_RS11735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC08_RS11750	COG0702	epimerase
FOC08_RS11755	COG2839	Protein conserved in bacteria
FOC08_RS11760	COG1253	flavin adenine dinucleotide binding
FOC08_RS11775	COG1114	Component of the transport system for branched-chain amino acids
FOC08_RS11780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC08_RS11800	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS11810	COG1876	peptidase activity
FOC08_RS11820	COG0154	amidase activity
FOC08_RS11825	COG2211	Major facilitator Superfamily
FOC08_RS11845	COG0561	phosphatase activity
FOC08_RS11855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC08_RS11875	COG1819	glycosyl
FOC08_RS11880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS11885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS11910	COG0456	acetyltransferase
FOC08_RS11960	COG3874	Sporulation protein YtfJ
FOC08_RS11985	COG2226	methyltransferase
FOC08_RS12010	COG0346	lactoylglutathione lyase activity
FOC08_RS12020	COG0604	alcohol dehydrogenase
FOC08_RS12025	COG1595	DNA-templated transcription, initiation
FOC08_RS12050	COG0386	Belongs to the glutathione peroxidase family
FOC08_RS12055	COG1305	Transglutaminase-like
FOC08_RS12060	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC08_RS12065	COG0714	Associated with various cellular activities
FOC08_RS12080	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC08_RS12085	COG1140	nitrate reductase beta subunit
FOC08_RS12090	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC08_RS12095	COG2181	nitrate reductase activity
FOC08_RS12115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC08_RS12120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC08_RS12125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC08_RS12130	COG0303	'Molybdopterin
FOC08_RS12135	COG0314	molybdopterin synthase activity
FOC08_RS12145	COG2223	nitrite transmembrane transporter activity
FOC08_RS12160	COG1648	precorrin-2 dehydrogenase activity
FOC08_RS12170	COG1587	Uroporphyrinogen-III synthase
FOC08_RS12170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC08_RS12175	COG2146	nitrite reductase [NAD(P)H] activity
FOC08_RS12180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC08_RS12185	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC08_RS12220	COG2359	stage V sporulation protein S
FOC08_RS12235	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS12250	COG1418	mRNA catabolic process
FOC08_RS12255	COG0488	(ABC) transporter
FOC08_RS12270	COG0629	single-stranded DNA binding
FOC08_RS12285	COG1413	lyase activity
FOC08_RS12300	COG2136	Putative SAM-dependent methyltransferase
FOC08_RS12300	COG2521	methyltransferase
FOC08_RS12305	COG0018	arginyl-trna synthetase
FOC08_RS12330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC08_RS12350	COG0017	Asparaginyl-tRNA synthetase
FOC08_RS12370	COG1674	ftsk spoiiie
FOC08_RS12440	COG1929	Belongs to the glycerate kinase type-1 family
FOC08_RS12445	COG0471	metal ion transport
FOC08_RS12450	COG0745	RESPONSE REGULATOR receiver
FOC08_RS12455	COG3850	Histidine kinase
FOC08_RS12455	COG5002	protein histidine kinase activity
FOC08_RS12470	COG0733	neurotransmitter:sodium symporter activity
FOC08_RS12495	COG2610	gluconate transmembrane transporter activity
FOC08_RS12500	COG1454	alcohol dehydrogenase
FOC08_RS12505	COG1794	racemase activity, acting on amino acids and derivatives
FOC08_RS12515	COG0456	acetyltransferase
FOC08_RS12530	COG1131	(ABC) transporter
FOC08_RS12545	COG0546	phosphoglycolate phosphatase activity
FOC08_RS12565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC08_RS12580	COG0768	penicillin binding
FOC08_RS12585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC08_RS12590	COG0204	Acyl-transferase
FOC08_RS12595	COG1272	protein, Hemolysin III
FOC08_RS12605	COG0805	protein transport
FOC08_RS12615	COG1307	EDD domain protein, DegV family
FOC08_RS12620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC08_RS12625	COG1999	signal sequence binding
FOC08_RS12630	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC08_RS12635	COG0367	asparagine synthase
FOC08_RS12650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS12655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC08_RS12680	COG1051	belongs to the nudix hydrolase family
FOC08_RS12690	COG0668	transmembrane transport
FOC08_RS12695	COG2203	Gaf domain
FOC08_RS12695	COG4585	Histidine kinase
FOC08_RS12700	COG2197	response regulator
FOC08_RS12710	COG1064	alcohol dehydrogenase
FOC08_RS12735	COG1070	Carbohydrate kinase
FOC08_RS12770	COG1125	glycine betaine transport
FOC08_RS12770	COG0517	IMP dehydrogenase activity
FOC08_RS12775	COG1174	glycine betaine transport
FOC08_RS12810	COG1253	flavin adenine dinucleotide binding
FOC08_RS12815	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS12820	COG5506	Protein of unknown function (DUF1694)
FOC08_RS12835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC08_RS12840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC08_RS12845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC08_RS12850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC08_RS12855	COG0456	acetyltransferase
FOC08_RS12860	COG3829	transcription factor binding
FOC08_RS12865	COG1509	lysine 2,3-aminomutase activity
FOC08_RS12905	COG4326	sporulation control protein
FOC08_RS12910	COG0671	phosphoesterase, PA-phosphatase related
FOC08_RS12915	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC08_RS12920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC08_RS12950	COG1787	Restriction endonuclease
FOC08_RS12950	COG1715	Restriction endonuclease
FOC08_RS13040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC08_RS13080	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC08_RS13080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC08_RS13085	COG2814	Major facilitator Superfamily
FOC08_RS13090	COG4841	protein insertion into membrane
FOC08_RS13095	COG0372	Belongs to the citrate synthase family
FOC08_RS13100	COG2079	MmgE PrpD family protein
FOC08_RS13105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC08_RS13110	COG1960	acyl-CoA dehydrogenase activity
FOC08_RS13115	COG2084	Dehydrogenase
FOC08_RS13120	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS13125	COG1280	lysine exporter protein (LysE YggA)
FOC08_RS13130	COG1024	Enoyl-CoA hydratase
FOC08_RS13145	COG0420	3'-5' exonuclease activity
FOC08_RS13150	COG0419	ATPase involved in DNA repair
FOC08_RS13170	COG2223	nitrite transmembrane transporter activity
FOC08_RS13175	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS13180	COG1169	isochorismate synthase
FOC08_RS13185	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC08_RS13190	COG1535	isochorismatase
FOC08_RS13190	COG3433	isochorismatase activity
FOC08_RS13195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC08_RS13200	COG3251	PFAM MbtH domain protein
FOC08_RS13205	COG2814	Major facilitator Superfamily
FOC08_RS13220	COG0776	regulation of translation
FOC08_RS13230	COG2318	DinB family
FOC08_RS13240	COG1115	amino acid carrier protein
FOC08_RS13255	COG2329	Antibiotic biosynthesis monooxygenase
FOC08_RS13260	COG1187	pseudouridine synthase activity
FOC08_RS13265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC08_RS13280	COG0596	Alpha beta hydrolase
FOC08_RS13285	COG2814	Major facilitator Superfamily
FOC08_RS13305	COG2226	methyltransferase
FOC08_RS13350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS13385	COG1247	-acetyltransferase
FOC08_RS13425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS13435	COG1278	Cold shock
FOC08_RS13450	COG0010	Belongs to the arginase family
FOC08_RS13455	COG0561	phosphatase activity
FOC08_RS13490	COG0583	DNA-binding transcription factor activity
FOC08_RS13495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC08_RS13510	COG0583	DNA-binding transcription factor activity
FOC08_RS13515	COG2258	MOSC domain
FOC08_RS13530	COG1132	(ABC) transporter
FOC08_RS13535	COG1132	(ABC) transporter
FOC08_RS13555	COG1396	sequence-specific DNA binding
FOC08_RS13585	COG1595	DNA-templated transcription, initiation
FOC08_RS13635	COG2971	BadF BadG BcrA BcrD
FOC08_RS13640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC08_RS13645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC08_RS13665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS13695	COG1309	transcriptional regulator
FOC08_RS13710	COG0577	efflux transmembrane transporter activity
FOC08_RS13710	COG1136	(ABC) transporter
FOC08_RS13715	COG3615	Tellurite resistance protein tehB
FOC08_RS13715	COG0500	methyltransferase
FOC08_RS13725	COG2226	methyltransferase
FOC08_RS13730	COG3961	Belongs to the TPP enzyme family
FOC08_RS13735	COG1846	Transcriptional regulator
FOC08_RS13765	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC08_RS13780	COG1595	DNA-templated transcription, initiation
FOC08_RS13790	COG0768	penicillin binding
FOC08_RS13800	COG2367	Beta-lactamase
FOC08_RS13805	COG0671	phosphoesterase, PA-phosphatase related
FOC08_RS13810	COG1609	Transcriptional regulator
FOC08_RS13815	COG2814	Major facilitator Superfamily
FOC08_RS13820	COG0673	inositol 2-dehydrogenase activity
FOC08_RS13830	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS13850	COG3718	enzyme involved in inositol metabolism
FOC08_RS13875	COG0457	Tetratricopeptide repeat
FOC08_RS13880	COG1476	TRANSCRIPTIONal
FOC08_RS13895	COG1876	peptidase activity
FOC08_RS13915	COG1309	transcriptional regulator
FOC08_RS13935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS13950	COG1252	NADH dehydrogenase
FOC08_RS13955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC08_RS13970	COG1131	(ABC) transporter
FOC08_RS13980	COG1309	transcriptional regulator
FOC08_RS13995	COG1960	acyl-CoA dehydrogenase activity
FOC08_RS14000	COG0439	Biotin carboxylase
FOC08_RS14005	COG0511	ligase activity, forming carbon-carbon bonds
FOC08_RS14010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC08_RS14015	COG1024	Enoyl-CoA hydratase
FOC08_RS14020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC08_RS14025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC08_RS14035	COG1247	-acetyltransferase
FOC08_RS14040	COG0572	uridine kinase
FOC08_RS14050	COG2318	DinB family
FOC08_RS14055	COG1686	Belongs to the peptidase S11 family
FOC08_RS14080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC08_RS14120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC08_RS14120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC08_RS14135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC08_RS14145	COG2814	Major facilitator Superfamily
FOC08_RS14160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC08_RS14180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS14195	COG1063	alcohol dehydrogenase
FOC08_RS14220	COG3773	Cell wall hydrolase
FOC08_RS14230	COG0745	RESPONSE REGULATOR receiver
FOC08_RS14260	COG1136	(ABC) transporter
FOC08_RS14285	COG0460	homoserine dehydrogenase
FOC08_RS14290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS14300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC08_RS14365	COG2124	cytochrome p450
FOC08_RS14400	COG0561	phosphatase activity
FOC08_RS14410	COG5002	protein histidine kinase activity
FOC08_RS14420	COG1819	glycosyl
FOC08_RS14425	COG1794	racemase activity, acting on amino acids and derivatives
FOC08_RS14435	COG1122	ATPase activity
FOC08_RS14450	COG2205	protein histidine kinase activity
FOC08_RS14465	COG0604	alcohol dehydrogenase
FOC08_RS14480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC08_RS14515	COG0693	protein deglycase activity
FOC08_RS14545	COG2814	Major facilitator Superfamily
FOC08_RS14560	COG0584	glycerophosphoryl diester phosphodiesterase
FOC08_RS14580	COG0697	spore germination
FOC08_RS14610	COG2223	nitrite transmembrane transporter activity
FOC08_RS14625	COG2816	NAD+ diphosphatase activity
FOC08_RS14630	COG0592	DNA-directed DNA polymerase activity
FOC08_RS14635	COG1051	belongs to the nudix hydrolase family
FOC08_RS14670	COG3878	Protein conserved in bacteria
FOC08_RS14720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC08_RS14735	COG0322	excinuclease ABC activity
FOC08_RS14775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC08_RS14800	COG1011	Hydrolase
FOC08_RS14820	COG0076	glutamate decarboxylase activity
FOC08_RS14835	COG1523	belongs to the glycosyl hydrolase 13 family
FOC08_RS14840	COG3227	Zinc metalloprotease (Elastase)
FOC08_RS14860	COG0201	protein transport
FOC08_RS14870	COG0697	spore germination
FOC08_RS14875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS14905	COG4129	membrane
FOC08_RS14910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS14925	COG2959	enzyme of heme biosynthesis
FOC08_RS14930	COG3773	Cell wall hydrolase
FOC08_RS14930	COG3409	Peptidoglycan-binding domain 1 protein
FOC08_RS14945	COG3483	tryptophan 2,3-dioxygenase activity
FOC08_RS14950	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC08_RS14955	COG3844	kynureninase activity
FOC08_RS14960	COG1309	transcriptional regulator
FOC08_RS14990	COG3284	Transcriptional regulator
FOC08_RS15005	COG1349	DNA-binding transcription factor activity
FOC08_RS15025	COG1959	2 iron, 2 sulfur cluster binding
FOC08_RS15040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC08_RS15045	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC08_RS15050	COG0022	dehydrogenase e1 component
FOC08_RS15055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC08_RS15065	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS15070	COG0456	acetyltransferase
FOC08_RS15070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC08_RS15100	COG4176	ABC-type proline glycine betaine transport system permease component
FOC08_RS15105	COG0517	IMP dehydrogenase activity
FOC08_RS15105	COG4175	Glycine betaine
FOC08_RS15115	COG0740	serine-type endopeptidase activity
FOC08_RS15130	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC08_RS15135	COG2153	protein acetylation
FOC08_RS15140	COG3397	chitin binding
FOC08_RS15155	COG2205	protein histidine kinase activity
FOC08_RS15175	COG2333	competence protein COMEC
FOC08_RS15175	COG0658	competence protein
FOC08_RS15225	COG3973	AAA domain
FOC08_RS15240	COG2105	PFAM AIG2 family protein
FOC08_RS15245	COG0514	ATP-dependent DNA helicase (RecQ)
FOC08_RS15265	COG4637	Psort location Cytoplasmic, score
FOC08_RS15290	COG3397	chitin binding
FOC08_RS15305	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC08_RS15310	COG1115	amino acid carrier protein
FOC08_RS15315	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS15320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC08_RS15330	COG3938	Belongs to the proline racemase family
FOC08_RS15335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC08_RS15375	COG0586	Pfam SNARE associated Golgi protein
FOC08_RS15390	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC08_RS15395	COG0519	Catalyzes the synthesis of GMP from XMP
FOC08_RS15400	COG4166	transmembrane transport
FOC08_RS15410	COG4948	Mandelate Racemase Muconate Lactonizing
FOC08_RS15455	COG2936	dipeptidyl-peptidase activity
FOC08_RS15460	COG5002	protein histidine kinase activity
FOC08_RS15500	COG1164	Oligoendopeptidase f
FOC08_RS15515	COG1307	EDD domain protein, DegV family
FOC08_RS15535	COG2814	Major facilitator Superfamily
FOC08_RS15545	COG1664	Polymer-forming cytoskeletal
FOC08_RS15550	COG0789	Transcriptional regulator
FOC08_RS15555	COG4533	DNA binding
FOC08_RS15560	COG0477	Major facilitator Superfamily
FOC08_RS15560	COG2814	Major facilitator Superfamily
FOC08_RS15580	COG2261	transglycosylase associated protein
FOC08_RS15595	COG2226	methyltransferase
FOC08_RS15630	COG0436	Aminotransferase
FOC08_RS15635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC08_RS15640	COG5146	pantothenate kinase activity
FOC08_RS15700	COG0628	permease
FOC08_RS15710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC08_RS15715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC08_RS15720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC08_RS15725	COG1116	anion transmembrane transporter activity
FOC08_RS15765	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC08_RS15790	COG0697	spore germination
FOC08_RS15795	COG2318	DinB family
FOC08_RS15815	COG4912	Dna alkylation repair
FOC08_RS15825	COG0726	polysaccharide deacetylase
FOC08_RS15835	COG0861	Integral membrane protein TerC family
FOC08_RS15840	COG1368	sulfuric ester hydrolase activity
FOC08_RS15845	COG0488	(ABC) transporter
FOC08_RS15855	COG1033	growth of symbiont in host cell
FOC08_RS15855	COG2409	Drug exporters of the RND superfamily
FOC08_RS15860	COG1033	growth of symbiont in host cell
FOC08_RS15860	COG2409	Drug exporters of the RND superfamily
FOC08_RS15865	COG2409	Drug exporters of the RND superfamily
FOC08_RS15865	COG1033	growth of symbiont in host cell
FOC08_RS15870	COG1309	transcriptional regulator
FOC08_RS15885	COG0287	Prephenate dehydrogenase
FOC08_RS15890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC08_RS15895	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC08_RS15900	COG1605	Chorismate mutase
FOC08_RS15900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC08_RS15935	COG1388	LysM domain
FOC08_RS15935	COG3584	3D domain protein
FOC08_RS15945	COG1595	DNA-templated transcription, initiation
FOC08_RS15970	COG1879	ABC-type sugar transport system periplasmic component
FOC08_RS15980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC08_RS15990	COG2390	Transcriptional regulator
FOC08_RS16025	COG2329	Antibiotic biosynthesis monooxygenase
FOC08_RS16045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS16055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC08_RS16060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC08_RS16065	COG4187	Peptidase family M20/M25/M40
FOC08_RS16070	COG1414	Transcriptional regulator
FOC08_RS16075	COG0833	amino acid
FOC08_RS16080	COG1690	Belongs to the RtcB family
FOC08_RS16085	COG3239	Fatty acid desaturase
FOC08_RS16090	COG1785	Belongs to the alkaline phosphatase family
FOC08_RS16100	COG3655	Transcriptional regulator
FOC08_RS16115	COG4377	Putative membrane peptidase family (DUF2324)
FOC08_RS16125	COG3279	Response regulator of the LytR AlgR family
FOC08_RS16135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS16140	COG0346	lactoylglutathione lyase activity
FOC08_RS16160	COG0714	Associated with various cellular activities
FOC08_RS16185	COG0463	Glycosyl transferase, family 2
FOC08_RS16210	COG0463	Glycosyl transferase, family 2
FOC08_RS16220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC08_RS16225	COG0753	catalase activity
FOC08_RS16235	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC08_RS16260	COG0714	Associated with various cellular activities
FOC08_RS16270	COG0778	Nitroreductase
FOC08_RS16275	COG1846	Transcriptional regulator
FOC08_RS16310	COG1725	Transcriptional regulator
FOC08_RS16320	COG0577	efflux transmembrane transporter activity
FOC08_RS16320	COG1136	(ABC) transporter
FOC08_RS16345	COG2207	Transcriptional regulator
FOC08_RS16350	COG0456	acetyltransferase
FOC08_RS16370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS16390	COG0642	Histidine kinase
FOC08_RS16395	COG0745	RESPONSE REGULATOR receiver
FOC08_RS16400	COG0596	Alpha beta hydrolase
FOC08_RS16430	COG0730	response to heat
FOC08_RS16440	COG0833	amino acid
FOC08_RS16450	COG4335	DNA alkylation repair
FOC08_RS16495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC08_RS16525	COG1984	allophanate hydrolase subunit 2
FOC08_RS16530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC08_RS16535	COG1414	Transcriptional regulator
FOC08_RS16550	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS16555	COG0640	Transcriptional regulator
FOC08_RS16565	COG1960	acyl-CoA dehydrogenase activity
FOC08_RS16595	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC08_RS16610	COG3848	Pyruvate phosphate dikinase
FOC08_RS16610	COG0574	Belongs to the PEP-utilizing enzyme family
FOC08_RS16615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS16630	COG5577	PFAM Coat F domain
FOC08_RS16635	COG3403	YqcI/YcgG family
FOC08_RS16640	COG1280	lysine exporter protein (LysE YggA)
FOC08_RS16670	COG1063	alcohol dehydrogenase
FOC08_RS16685	COG1027	Aspartate ammonia-lyase
FOC08_RS16690	COG0252	asparaginase activity
FOC08_RS16695	COG1396	sequence-specific DNA binding
FOC08_RS16705	COG0322	excinuclease ABC activity
FOC08_RS16710	COG0531	amino acid
FOC08_RS16715	COG1114	Component of the transport system for branched-chain amino acids
FOC08_RS16720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC08_RS16730	COG0281	malic enzyme
FOC08_RS16755	COG0784	Response regulator, receiver
FOC08_RS16765	COG2066	Belongs to the glutaminase family
FOC08_RS16800	COG0737	Belongs to the 5'-nucleotidase family
FOC08_RS16805	COG0753	catalase activity
FOC08_RS16810	COG2267	carboxylic ester hydrolase activity
FOC08_RS16815	COG1335	isochorismatase
FOC08_RS16835	COG0583	DNA-binding transcription factor activity
FOC08_RS16840	COG1846	Transcriptional regulator
FOC08_RS16880	COG0415	Belongs to the DNA photolyase family
FOC08_RS16885	COG0288	reversible hydration of carbon dioxide
FOC08_RS16895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC08_RS16900	COG5609	conserved protein (DUF2294)
FOC08_RS16915	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC08_RS16920	COG2267	carboxylic ester hydrolase activity
FOC08_RS16925	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC08_RS16930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC08_RS16935	COG1121	(ABC) transporter
FOC08_RS16965	COG0798	PFAM Bile acid sodium symporter
FOC08_RS16970	COG0346	lactoylglutathione lyase activity
FOC08_RS16975	COG0640	Transcriptional regulator
FOC08_RS16990	COG0443	Heat shock 70 kDa protein
FOC08_RS17005	COG1522	sequence-specific DNA binding
FOC08_RS17020	COG0346	lactoylglutathione lyase activity
FOC08_RS17045	COG2169	Transcriptional regulator
FOC08_RS17085	COG2814	Major facilitator Superfamily
FOC08_RS17110	COG0745	RESPONSE REGULATOR receiver
FOC08_RS17115	COG3850	Histidine kinase
FOC08_RS17115	COG5002	protein histidine kinase activity
FOC08_RS17140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC08_RS17160	COG1476	TRANSCRIPTIONal
FOC08_RS17175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS17180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC08_RS17190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC08_RS17195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC08_RS17210	COG1136	(ABC) transporter
FOC08_RS17215	COG0577	efflux transmembrane transporter activity
FOC08_RS17230	COG5002	protein histidine kinase activity
FOC08_RS17230	COG3850	Histidine kinase
FOC08_RS17240	COG2364	Membrane
FOC08_RS17245	COG1846	Transcriptional regulator
FOC08_RS17255	COG2808	Putative FMN-binding domain
FOC08_RS17260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS17265	COG2271	Major facilitator Superfamily
FOC08_RS17270	COG1556	Lactate utilization protein
FOC08_RS17275	COG1139	Iron-sulfur cluster binding protein
FOC08_RS17285	COG0583	DNA-binding transcription factor activity
FOC08_RS17295	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC08_RS17315	COG0738	Major facilitator superfamily
FOC08_RS17320	COG0673	inositol 2-dehydrogenase activity
FOC08_RS17325	COG0561	phosphatase activity
FOC08_RS17335	COG1609	Transcriptional regulator
FOC08_RS17340	COG0457	Tetratricopeptide repeat
FOC08_RS17355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC08_RS17385	COG0534	Mate efflux family protein
FOC08_RS17405	COG2814	Major facilitator Superfamily
FOC08_RS17410	COG1309	transcriptional regulator
FOC08_RS17425	COG0814	amino acid
FOC08_RS17430	COG1760	l-serine dehydratase
FOC08_RS17435	COG1760	l-serine dehydratase
FOC08_RS17445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC08_RS17450	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC08_RS17460	COG1335	isochorismatase
FOC08_RS17465	COG1522	sequence-specific DNA binding
FOC08_RS17470	COG0531	amino acid
FOC08_RS17485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC08_RS17505	COG1595	DNA-templated transcription, initiation
FOC08_RS17520	COG0662	Cupin 2, conserved barrel domain protein
FOC08_RS17525	COG2207	Transcriptional regulator
FOC08_RS17525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS17575	COG0477	Major facilitator Superfamily
FOC08_RS17585	COG1846	Transcriptional regulator
FOC08_RS17590	COG2814	Major facilitator Superfamily
FOC08_RS17605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC08_RS17610	COG1131	(ABC) transporter
FOC08_RS17630	COG2076	Multidrug Resistance protein
FOC08_RS17635	COG1309	transcriptional regulator
FOC08_RS17645	COG2031	fatty acid transporter
FOC08_RS17655	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC08_RS17685	COG1122	ATPase activity
FOC08_RS17690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC08_RS17705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC08_RS17710	COG1288	antiporter activity
FOC08_RS17715	COG2356	endonuclease I
FOC08_RS17730	COG3620	sequence-specific DNA binding
FOC08_RS17735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC08_RS17740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC08_RS17745	COG0124	histidyl-tRNA synthetase
FOC08_RS17760	COG1733	regulation of RNA biosynthetic process
FOC08_RS17765	COG0778	Nitroreductase
FOC08_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS17795	COG1131	(ABC) transporter
FOC08_RS17820	COG1011	Hydrolase
FOC08_RS17855	COG0346	lactoylglutathione lyase activity
FOC08_RS17860	COG1940	carbohydrate kinase activity
FOC08_RS17865	COG0738	Major facilitator superfamily
FOC08_RS17870	COG0110	maltose O-acetyltransferase activity
FOC08_RS17880	COG1136	(ABC) transporter
FOC08_RS17885	COG0180	Tryptophanyl-tRNA synthetase
FOC08_RS17890	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC08_RS17895	COG0628	permease
FOC08_RS17910	COG2226	methyltransferase
FOC08_RS17920	COG0477	Major facilitator Superfamily
FOC08_RS17950	COG1253	flavin adenine dinucleotide binding
FOC08_RS17955	COG0789	Transcriptional regulator
FOC08_RS17960	COG0697	spore germination
FOC08_RS17965	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC08_RS17970	COG3813	Protein conserved in bacteria
FOC08_RS17975	COG2706	6-phosphogluconolactonase activity
FOC08_RS17980	COG1070	Carbohydrate kinase
FOC08_RS17990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC08_RS17995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC08_RS18005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC08_RS18010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC08_RS18015	COG0604	alcohol dehydrogenase
FOC08_RS18020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC08_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS18060	COG0656	L-ascorbic acid biosynthetic process
FOC08_RS18065	COG2814	Major facilitator Superfamily
FOC08_RS18080	COG0346	lactoylglutathione lyase activity
FOC08_RS18085	COG0814	amino acid
FOC08_RS18110	COG1393	Belongs to the ArsC family
FOC08_RS18115	COG1733	regulation of RNA biosynthetic process
FOC08_RS18120	COG2188	Transcriptional regulator
FOC08_RS18130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC08_RS18135	COG1733	regulation of RNA biosynthetic process
FOC08_RS18140	COG1733	regulation of RNA biosynthetic process
FOC08_RS18155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS18175	COG0384	phenazine biosynthesis protein PhzF
FOC08_RS18185	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS18195	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS18205	COG1733	regulation of RNA biosynthetic process
FOC08_RS18240	COG1191	sigma factor activity
FOC08_RS18255	COG1309	transcriptional regulator
FOC08_RS18275	COG3152	Membrane
FOC08_RS18300	COG1151	hydroxylamine reductase activity
FOC08_RS18310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS18315	COG3409	Peptidoglycan-binding domain 1 protein
FOC08_RS18315	COG3757	hydrolase, family 25
FOC08_RS18350	COG2072	flavoprotein involved in K transport
FOC08_RS18390	COG1113	amino acid transport
FOC08_RS18395	COG2814	Major facilitator Superfamily
FOC08_RS18425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC08_RS18430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC08_RS18450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS18465	COG3739	integral membrane protein
FOC08_RS18470	COG0384	phenazine biosynthesis protein PhzF
FOC08_RS18500	COG0583	DNA-binding transcription factor activity
FOC08_RS18520	COG1193	negative regulation of DNA recombination
FOC08_RS18540	COG1164	Oligoendopeptidase f
FOC08_RS18545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC08_RS18575	COG0584	glycerophosphoryl diester phosphodiesterase
FOC08_RS18600	COG0640	Transcriptional regulator
FOC08_RS18605	COG0604	alcohol dehydrogenase
FOC08_RS18625	COG2808	Putative FMN-binding domain
FOC08_RS18630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC08_RS18640	COG0385	Bile acid
FOC08_RS18645	COG0277	FAD linked oxidase domain protein
FOC08_RS18675	COG1216	Glycosyl transferase, family 2
FOC08_RS18680	COG1024	Enoyl-CoA hydratase
FOC08_RS18690	COG1285	pathogenesis
FOC08_RS18705	COG2514	catechol 2,3-dioxygenase activity
FOC08_RS18710	COG2720	vancomycin resistance protein
FOC08_RS18735	COG1278	Cold shock
FOC08_RS18745	COG0716	FMN binding
FOC08_RS18775	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS18785	COG0165	Argininosuccinate lyase
FOC08_RS18800	COG4145	pantothenate transmembrane transporter activity
FOC08_RS18810	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS18815	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS18825	COG1657	PFAM Prenyltransferase squalene oxidase
FOC08_RS18830	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC08_RS18835	COG2962	Rard protein
FOC08_RS18840	COG3326	Membrane
FOC08_RS18855	COG0489	protein tyrosine kinase activity
FOC08_RS18865	COG0314	molybdopterin synthase activity
FOC08_RS18870	COG0303	'Molybdopterin
FOC08_RS18875	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC08_RS18880	COG2116	formate transmembrane transporter activity
FOC08_RS18890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC08_RS18895	COG5609	conserved protein (DUF2294)
FOC08_RS18900	COG2427	Protein of unknown function (DUF1641)
FOC08_RS18905	COG3383	formate dehydrogenase (NAD+) activity
FOC08_RS18910	COG0697	spore germination
FOC08_RS18950	COG2226	methyltransferase
FOC08_RS18955	COG4166	transmembrane transport
FOC08_RS18960	COG4166	transmembrane transport
FOC08_RS18965	COG4166	transmembrane transport
FOC08_RS18975	COG1316	TRANSCRIPTIONal
FOC08_RS18985	COG1595	DNA-templated transcription, initiation
FOC08_RS19000	COG1131	(ABC) transporter
FOC08_RS19010	COG0673	inositol 2-dehydrogenase activity
FOC08_RS19015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC08_RS19020	COG0187	DNA topoisomerase II activity
FOC08_RS19025	COG1832	CoA-binding protein
FOC08_RS19030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC08_RS19035	COG0745	RESPONSE REGULATOR receiver
FOC08_RS19050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC08_RS19055	COG4841	protein insertion into membrane
FOC08_RS19060	COG0824	Thioesterase
FOC08_RS19090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC08_RS19100	COG2274	protein secretion by the type I secretion system
FOC08_RS19105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC08_RS19115	COG0726	polysaccharide deacetylase
FOC08_RS19145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC08_RS19160	COG0183	Belongs to the thiolase family
FOC08_RS19165	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS19170	COG1268	BioY protein
FOC08_RS19175	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS19225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS19235	COG5002	protein histidine kinase activity
FOC08_RS19240	COG0400	carboxylic ester hydrolase activity
FOC08_RS19245	COG0346	lactoylglutathione lyase activity
FOC08_RS19250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC08_RS19255	COG0069	glutamate synthase activity
FOC08_RS19260	COG1902	pentaerythritol trinitrate reductase activity
FOC08_RS19265	COG1329	Transcriptional regulator
FOC08_RS19270	COG0010	Belongs to the arginase family
FOC08_RS19295	COG2226	methyltransferase
FOC08_RS19350	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC08_RS19355	COG0785	Cytochrome C biogenesis protein
FOC08_RS19365	COG0583	DNA-binding transcription factor activity
FOC08_RS19370	COG1380	Effector of murein hydrolase LrgA
FOC08_RS19375	COG1346	cytolysis
FOC08_RS19400	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS19400	COG3409	Peptidoglycan-binding domain 1 protein
FOC08_RS19415	COG1132	(ABC) transporter
FOC08_RS19420	COG1132	(ABC) transporter
FOC08_RS19450	COG3639	organic phosphonate transmembrane transporter activity
FOC08_RS19455	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC08_RS19475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC08_RS19495	COG1695	Transcriptional regulator
FOC08_RS19525	COG1388	LysM domain
FOC08_RS19525	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC08_RS19525	COG3409	Peptidoglycan-binding domain 1 protein
FOC08_RS19530	COG4824	toxin secretion phage lysis holin
FOC08_RS19675	COG1595	DNA-templated transcription, initiation
FOC08_RS19710	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC08_RS19790	COG1396	sequence-specific DNA binding
FOC08_RS19810	COG0174	glutamine synthetase
FOC08_RS19815	COG0789	Transcriptional regulator
FOC08_RS19820	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC08_RS19830	COG2860	membrane
FOC08_RS19840	COG0464	growth
FOC08_RS19870	COG3584	3D domain protein
FOC08_RS19870	COG1388	LysM domain
FOC08_RS19875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC08_RS19875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC08_RS19875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC08_RS19880	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC08_RS19885	COG1349	DNA-binding transcription factor activity
FOC08_RS19895	COG2322	membrane
FOC08_RS19905	COG1113	amino acid transport
FOC08_RS19915	COG1408	metallophosphoesterase
FOC08_RS19920	COG2116	formate transmembrane transporter activity
FOC08_RS19930	COG2217	Heavy metal translocating P-type atpase
FOC08_RS19935	COG2608	mercury ion transmembrane transporter activity
FOC08_RS19940	COG1937	Protein conserved in bacteria
FOC08_RS19950	COG2819	hydrolase of the alpha beta superfamily
FOC08_RS19955	COG1120	ATPase activity
FOC08_RS19960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS19965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC08_RS19975	COG0708	Exodeoxyribonuclease III
FOC08_RS19980	COG2169	Transcriptional regulator
FOC08_RS19985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC08_RS19990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC08_RS20000	COG2364	Membrane
FOC08_RS20015	COG2267	carboxylic ester hydrolase activity
FOC08_RS20020	COG0346	lactoylglutathione lyase activity
FOC08_RS20025	COG5001	Diguanylate cyclase
FOC08_RS20025	COG3300	MHYT domain
FOC08_RS20040	COG1346	cytolysis
FOC08_RS20045	COG1380	Effector of murein hydrolase LrgA
FOC08_RS20050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC08_RS20055	COG0596	Alpha beta hydrolase
FOC08_RS20055	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC08_RS20060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC08_RS20080	COG1404	Belongs to the peptidase S8 family
FOC08_RS20085	COG3773	Cell wall hydrolase
FOC08_RS20090	COG0562	UDP-galactopyranose mutase
FOC08_RS20095	COG1368	sulfuric ester hydrolase activity
FOC08_RS20100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC08_RS20110	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC08_RS20155	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC08_RS20160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC08_RS20165	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC08_RS20170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC08_RS20170	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC08_RS20180	COG2359	stage V sporulation protein S
FOC08_RS20185	COG1692	metallophosphoesterase
FOC08_RS20210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC08_RS20215	COG1426	Protein conserved in bacteria
FOC08_RS20230	COG0300	oxidoreductase activity
FOC08_RS20235	COG0612	Peptidase, M16
FOC08_RS20240	COG0612	Peptidase, M16
FOC08_RS20265	COG2188	Transcriptional regulator
FOC08_RS20270	COG1674	ftsk spoiiie
FOC08_RS20280	COG0740	serine-type endopeptidase activity
FOC08_RS20285	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC08_RS20295	COG0527	aspartate kinase activity
FOC08_RS20300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC08_RS20305	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC08_RS20310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC08_RS20315	COG1873	PFAM PRC-barrel domain
FOC08_RS20320	COG0612	Peptidase, M16
FOC08_RS20325	COG0726	polysaccharide deacetylase
FOC08_RS20340	COG0196	riboflavin kinase activity
FOC08_RS20345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC08_RS20355	COG1550	Protein conserved in bacteria
FOC08_RS20365	COG1358	cellular component organization or biogenesis
FOC08_RS20370	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC08_RS20375	COG0195	Participates in both transcription termination and antitermination
FOC08_RS20395	COG0750	zinc metalloprotease
FOC08_RS20400	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC08_RS20405	COG4589	Belongs to the CDS family
FOC08_RS20410	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC08_RS20420	COG0528	UMP kinase activity
FOC08_RS20450	COG4974	Belongs to the 'phage' integrase family
FOC08_RS20460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC08_RS20470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC08_RS20510	COG1837	Belongs to the UPF0109 family
FOC08_RS20520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC08_RS20530	COG0552	protein localization to endoplasmic reticulum
FOC08_RS20535	COG1196	nuclear chromosome segregation
FOC08_RS20550	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS20555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC08_RS20570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC08_RS20575	COG1461	Dihydroxyacetone kinase
FOC08_RS20580	COG1302	Protein conserved in bacteria
FOC08_RS20595	COG1564	THIamine pyrophosphokinase
FOC08_RS20600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC08_RS20605	COG1162	GTPase activity
FOC08_RS20610	COG0515	serine threonine protein kinase
FOC08_RS20610	COG2815	serine threonine protein kinase
FOC08_RS20615	COG0631	protein serine/threonine phosphatase activity
FOC08_RS20625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC08_RS20625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC08_RS20635	COG0242	peptide deformylase activity
FOC08_RS20640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC08_RS20645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC08_RS20655	COG0194	GDP metabolic process
FOC08_RS20665	COG1561	YicC-like family, N-terminal region
FOC08_RS20670	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC08_RS20680	COG0006	proline dipeptidase activity
FOC08_RS20695	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC08_RS20735	COG0505	Belongs to the CarA family
FOC08_RS20760	COG0564	pseudouridine synthase activity
FOC08_RS20775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC08_RS20780	COG3599	regulation of cell shape
FOC08_RS20785	COG2302	S4 RNA-binding domain
FOC08_RS20790	COG0762	integral membrane protein
FOC08_RS20800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC08_RS20810	COG1873	PFAM PRC-barrel domain
FOC08_RS20815	COG1191	sigma factor activity
FOC08_RS20820	COG1191	sigma factor activity
FOC08_RS20830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC08_RS20835	COG0849	cell division
FOC08_RS20840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC08_RS20845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC08_RS20850	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC08_RS20855	COG0772	Belongs to the SEDS family
FOC08_RS20870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC08_RS20875	COG0768	penicillin binding
FOC08_RS20885	COG4839	cell division protein FtsL
FOC08_RS20900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC08_RS20925	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC08_RS20975	COG4824	toxin secretion phage lysis holin
FOC08_RS21065	COG1802	Transcriptional regulator
FOC08_RS21065	COG4626	Terminase
FOC08_RS21090	COG0582	viral genome integration into host DNA
FOC08_RS21165	COG1191	sigma factor activity
FOC08_RS21190	COG1484	DNA-dependent DNA replication
FOC08_RS21210	COG1396	sequence-specific DNA binding
FOC08_RS21220	COG1396	sequence-specific DNA binding
FOC08_RS21230	COG0582	viral genome integration into host DNA
FOC08_RS21240	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC08_RS21245	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC08_RS21250	COG3314	Sporulation integral membrane protein YlbJ
FOC08_RS21260	COG0742	ribosomal rna small subunit methyltransferase
FOC08_RS21275	COG3679	Belongs to the UPF0342 family
FOC08_RS21280	COG0406	alpha-ribazole phosphatase activity
FOC08_RS21295	COG2340	Cysteine-rich secretory protein family
FOC08_RS21310	COG3336	cytochrome c oxidase
FOC08_RS21345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC08_RS21350	COG0772	Belongs to the SEDS family
FOC08_RS21355	COG4838	Belongs to the UPF0358 family
FOC08_RS21360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC08_RS21365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC08_RS21375	COG4896	Protein conserved in bacteria
FOC08_RS21400	COG0483	inositol monophosphate 1-phosphatase activity
FOC08_RS21420	COG1982	Orn Lys Arg decarboxylase major
FOC08_RS21465	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC08_RS21470	COG0022	dehydrogenase e1 component
FOC08_RS21475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC08_RS21485	COG0242	peptide deformylase activity
FOC08_RS21490	COG0561	phosphatase activity
FOC08_RS21500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC08_RS21505	COG0569	domain protein
FOC08_RS21525	COG0583	DNA-binding transcription factor activity
FOC08_RS21530	COG0517	IMP dehydrogenase activity
FOC08_RS21540	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC08_RS21545	COG4703	Protein of unknown function (DUF1797)
FOC08_RS21560	COG2200	EAL domain
FOC08_RS21565	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS21570	COG1408	metallophosphoesterase
FOC08_RS21580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC08_RS21615	COG2814	Major facilitator Superfamily
FOC08_RS21635	COG3209	COG3209 Rhs family protein
FOC08_RS21645	COG2205	protein histidine kinase activity
FOC08_RS21655	COG0436	Aminotransferase
FOC08_RS21660	COG1609	Transcriptional regulator
FOC08_RS21665	COG3833	ABC-type maltose transport systems, permease component
FOC08_RS21670	COG1175	transmembrane transport
FOC08_RS21675	COG2182	Extracellular solute-binding protein
FOC08_RS21685	COG0366	Alpha amylase catalytic
FOC08_RS21690	COG3842	ATPase activity
FOC08_RS21730	COG0183	Belongs to the thiolase family
FOC08_RS21770	COG1695	Transcriptional regulator
FOC08_RS21775	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS21795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC08_RS21800	COG0436	Aminotransferase
FOC08_RS21820	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC08_RS21840	COG3706	GGDEF domain
FOC08_RS21845	COG0778	Nitroreductase
FOC08_RS21870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC08_RS21870	COG2190	(PTS) system
FOC08_RS21870	COG1263	PTS System
FOC08_RS21875	COG3711	transcriptional antiterminator
FOC08_RS21895	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC08_RS21920	COG1547	Domain of unknown function (DUF309)
FOC08_RS21925	COG0456	acetyltransferase
FOC08_RS21930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC08_RS21935	COG4086	secreted protein
FOC08_RS21940	COG0561	phosphatase activity
FOC08_RS21945	COG0697	spore germination
FOC08_RS21960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC08_RS21985	COG0733	neurotransmitter:sodium symporter activity
FOC08_RS22005	COG1686	Belongs to the peptidase S11 family
FOC08_RS22010	COG1725	Transcriptional regulator
FOC08_RS22015	COG1131	(ABC) transporter
FOC08_RS22030	COG1846	Transcriptional regulator
FOC08_RS22045	COG0598	Magnesium transport protein CorA
FOC08_RS22070	COG4974	Belongs to the 'phage' integrase family
FOC08_RS22080	COG0735	belongs to the Fur family
FOC08_RS22085	COG1300	Membrane
FOC08_RS22105	COG0667	Aldo Keto reductase
FOC08_RS22110	COG0656	L-ascorbic acid biosynthetic process
FOC08_RS22115	COG0456	acetyltransferase
FOC08_RS22115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC08_RS22125	COG4085	toxin activity
FOC08_RS22125	COG1525	nuclease
FOC08_RS22125	COG0737	Belongs to the 5'-nucleotidase family
FOC08_RS22135	COG0596	Alpha beta hydrolase
FOC08_RS22140	COG2056	Na+-H+ antiporter family
FOC08_RS22145	COG1609	Transcriptional regulator
FOC08_RS22150	COG0456	acetyltransferase
FOC08_RS22155	COG1073	alpha beta
FOC08_RS22170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC08_RS22170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC08_RS22175	COG0307	riboflavin synthase, alpha
FOC08_RS22195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC08_RS22200	COG4106	trans-aconitate 2-methyltransferase activity
FOC08_RS22205	COG1073	alpha beta
FOC08_RS22205	COG2226	methyltransferase
FOC08_RS22210	COG0156	8-amino-7-oxononanoate synthase activity
FOC08_RS22220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC08_RS22235	COG0737	Belongs to the 5'-nucleotidase family
FOC08_RS22245	COG1522	sequence-specific DNA binding
FOC08_RS22265	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC08_RS22275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC08_RS22290	COG0300	oxidoreductase activity
FOC08_RS22300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC08_RS22305	COG1760	l-serine dehydratase
FOC08_RS22310	COG1760	l-serine dehydratase
FOC08_RS22330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC08_RS22340	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC08_RS22345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS22360	COG1376	ErfK ybiS ycfS ynhG family protein
FOC08_RS22365	COG4129	membrane
FOC08_RS22370	COG1126	abc transporter atp-binding protein
FOC08_RS22375	COG0765	amino acid transport
FOC08_RS22380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC08_RS22400	COG0772	Belongs to the SEDS family
FOC08_RS22405	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC08_RS22410	COG0022	dehydrogenase e1 component
FOC08_RS22415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC08_RS22420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC08_RS22430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC08_RS22435	COG0280	phosphate acetyltransferase
FOC08_RS22440	COG3290	protein histidine kinase activity
FOC08_RS22440	COG3829	transcription factor binding
FOC08_RS22450	COG0584	glycerophosphoryl diester phosphodiesterase
FOC08_RS22455	COG3093	addiction module antidote protein HigA
FOC08_RS22465	COG0745	RESPONSE REGULATOR receiver
FOC08_RS22470	COG0750	zinc metalloprotease
FOC08_RS22475	COG0497	DNA recombination
FOC08_RS22485	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC08_RS22495	COG0142	geranyltranstransferase activity
FOC08_RS22520	COG1302	Protein conserved in bacteria
FOC08_RS22525	COG0439	Biotin carboxylase
FOC08_RS22530	COG0511	ligase activity, forming carbon-carbon bonds
FOC08_RS22575	COG3854	ATPases associated with a variety of cellular activities
FOC08_RS22600	COG0006	proline dipeptidase activity
FOC08_RS22615	COG3872	metal-dependent enzyme
FOC08_RS22625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC08_RS22645	COG0095	Lipoate-protein ligase
FOC08_RS22650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC08_RS22655	COG1609	Transcriptional regulator
FOC08_RS22665	COG2076	Multidrug Resistance protein
FOC08_RS22670	COG2076	Multidrug Resistance protein
FOC08_RS22705	COG1131	(ABC) transporter
FOC08_RS22710	COG1725	Transcriptional regulator
FOC08_RS22740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC08_RS22795	COG4970	Tfp pilus assembly protein FimT
FOC08_RS22805	COG1459	type II secretion system
FOC08_RS22810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC08_RS22860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC08_RS22865	COG0646	methionine synthase
FOC08_RS22865	COG1410	methionine synthase
FOC08_RS22870	COG0646	methionine synthase
FOC08_RS22870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC08_RS22875	COG0626	cystathionine gamma-synthase activity
FOC08_RS22880	COG0626	cystathionine gamma-synthase activity
FOC08_RS22900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS22910	COG1940	carbohydrate kinase activity
FOC08_RS22915	COG4483	Protein conserved in bacteria
FOC08_RS22920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC08_RS22930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC08_RS22935	COG0704	Plays a role in the regulation of phosphate uptake
FOC08_RS22940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC08_RS22945	COG0581	inorganic phosphate transmembrane transporter activity
FOC08_RS22950	COG0573	inorganic phosphate transmembrane transporter activity
FOC08_RS22955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC08_RS22965	COG0477	Major facilitator Superfamily
FOC08_RS22970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC08_RS22995	COG0735	belongs to the Fur family
FOC08_RS23000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC08_RS23005	COG1121	(ABC) transporter
FOC08_RS23010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS23040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC08_RS23045	COG2384	SAM-dependent methyltransferase
FOC08_RS23050	COG2010	Cytochrome c
FOC08_RS23055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC08_RS23060	COG0358	DNA primase activity
FOC08_RS23070	COG0517	IMP dehydrogenase activity
FOC08_RS23085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC08_RS23090	COG0295	cytidine deaminase activity
FOC08_RS23095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC08_RS23105	COG1480	7TM receptor with intracellular HD hydrolase
FOC08_RS23110	COG1702	phosphate starvation-inducible protein PhoH
FOC08_RS23125	COG1610	YqeY-like protein
FOC08_RS23135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC08_RS23140	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC08_RS23160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC08_RS23170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC08_RS23175	COG1733	regulation of RNA biosynthetic process
FOC08_RS23200	COG1466	dna polymerase III delta subunit
FOC08_RS23210	COG0658	competence protein
FOC08_RS23210	COG2333	competence protein COMEC
FOC08_RS23215	COG2131	deaminase
FOC08_RS23220	COG1596	polysaccharide export
FOC08_RS23220	COG1555	photosystem II stabilization
FOC08_RS23225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC08_RS23230	COG2226	methyltransferase
FOC08_RS23235	COG0799	negative regulation of ribosome biogenesis
FOC08_RS23240	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC08_RS23250	COG1534	Rna-binding protein
FOC08_RS23260	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC08_RS23265	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC08_RS23280	COG1191	sigma factor activity
FOC08_RS23290	COG1595	DNA-templated transcription, initiation
FOC08_RS23300	COG0778	Nitroreductase
FOC08_RS23305	COG2357	RelA SpoT domain protein
FOC08_RS23315	COG1785	Belongs to the alkaline phosphatase family
FOC08_RS23325	COG2267	carboxylic ester hydrolase activity
FOC08_RS23360	COG1404	Belongs to the peptidase S8 family
FOC08_RS23365	COG3186	Phenylalanine-4-hydroxylase
FOC08_RS23380	COG2259	Doxx family
FOC08_RS23420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC08_RS23430	COG1012	belongs to the aldehyde dehydrogenase family
FOC08_RS23430	COG1454	alcohol dehydrogenase
FOC08_RS23435	COG0626	cystathionine gamma-synthase activity
FOC08_RS23440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC08_RS23465	COG0768	penicillin binding
FOC08_RS23495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC08_RS23515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC08_RS23525	COG0628	permease
FOC08_RS23545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC08_RS23555	COG0482	sulfurtransferase activity
FOC08_RS23560	COG1104	cysteine desulfurase activity
FOC08_RS23565	COG1959	2 iron, 2 sulfur cluster binding
FOC08_RS23570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC08_RS23580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC08_RS23590	COG0124	histidyl-tRNA synthetase
FOC08_RS23600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC08_RS23610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC08_RS23610	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC08_RS23615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC08_RS23620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC08_RS23620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC08_RS23630	COG2244	polysaccharide biosynthetic process
FOC08_RS23635	COG2323	membrane
FOC08_RS23645	COG1862	Preprotein translocase
FOC08_RS23675	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC08_RS23685	COG0697	spore germination
FOC08_RS23690	COG0697	spore germination
FOC08_RS23695	COG0640	Transcriptional regulator
FOC08_RS23720	COG0157	Belongs to the NadC ModD family
FOC08_RS23725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC08_RS23730	COG1104	cysteine desulfurase activity
FOC08_RS23735	COG1827	regulation of RNA biosynthetic process
FOC08_RS23740	COG2258	MOSC domain
FOC08_RS23745	COG0077	Prephenate dehydratase
FOC08_RS23750	COG0577	efflux transmembrane transporter activity
FOC08_RS23755	COG0577	efflux transmembrane transporter activity
FOC08_RS23760	COG1136	(ABC) transporter
FOC08_RS23770	COG0745	RESPONSE REGULATOR receiver
FOC08_RS23775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC08_RS23790	COG2868	ribosomal protein
FOC08_RS23800	COG1530	ribonuclease E activity
FOC08_RS23805	COG1994	Peptidase M50
FOC08_RS23810	COG0739	heme binding
FOC08_RS23815	COG2894	cell division
FOC08_RS23830	COG1792	Involved in formation and maintenance of cell shape
FOC08_RS23835	COG1077	Cell shape determining protein MreB Mrl
FOC08_RS23855	COG0285	dihydrofolate synthase activity
FOC08_RS23860	COG0525	valine-tRNA ligase activity
FOC08_RS23870	COG1388	LysM domain
FOC08_RS23880	COG0113	porphobilinogen synthase activity
FOC08_RS23885	COG1587	Uroporphyrinogen-III synthase
FOC08_RS23895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC08_RS23905	COG1846	Transcriptional regulator
FOC08_RS23910	COG1764	response to oxidative stress
FOC08_RS23925	COG0470	DNA polymerase III
FOC08_RS23925	COG1067	ATP-dependent peptidase activity
FOC08_RS23970	COG0622	Phosphoesterase
FOC08_RS23975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC08_RS23985	COG5401	PFAM Sporulation and spore germination
FOC08_RS24005	COG1309	transcriptional regulator
FOC08_RS24020	COG2197	response regulator
FOC08_RS24025	COG2233	PERMEase
FOC08_RS24035	COG0402	S-adenosylhomocysteine deaminase activity
FOC08_RS24040	COG0402	S-adenosylhomocysteine deaminase activity
FOC08_RS24060	COG0444	Belongs to the ABC transporter superfamily
FOC08_RS24065	COG4608	Belongs to the ABC transporter superfamily
FOC08_RS24075	COG3279	Response regulator of the LytR AlgR family
FOC08_RS24090	COG1983	PspC domain protein
FOC08_RS24095	COG1396	sequence-specific DNA binding
FOC08_RS24100	COG0697	spore germination
FOC08_RS24110	COG1959	2 iron, 2 sulfur cluster binding
FOC08_RS24115	COG1668	transmembrane transport
FOC08_RS24120	COG4152	abc transporter atp-binding protein
FOC08_RS24125	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC08_RS24135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC08_RS24140	COG1876	peptidase activity
FOC08_RS24145	COG0824	Thioesterase
FOC08_RS24150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC08_RS24155	COG1053	succinate dehydrogenase
FOC08_RS24160	COG2009	succinate dehydrogenase
FOC08_RS24165	COG1719	4-vinyl reductase, 4VR
FOC08_RS24175	COG3118	belongs to the thioredoxin family
FOC08_RS24180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC08_RS24185	COG2086	electron transfer activity
FOC08_RS24190	COG1024	Enoyl-CoA hydratase
FOC08_RS24195	COG1309	transcriptional regulator
FOC08_RS24200	COG0318	PFAM AMP-dependent synthetase and ligase
FOC08_RS24220	COG2318	DinB family
FOC08_RS24245	COG1131	(ABC) transporter
FOC08_RS24250	COG2205	protein histidine kinase activity
FOC08_RS24255	COG0745	RESPONSE REGULATOR receiver
FOC08_RS24260	COG4895	conserved protein (DUF2196)
FOC08_RS24265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC08_RS24280	COG4509	Sortase family
FOC08_RS24285	COG1120	ATPase activity
FOC08_RS24300	COG5386	Cell surface protein
FOC08_RS24310	COG5386	Cell surface protein
FOC08_RS24315	COG1114	Component of the transport system for branched-chain amino acids
FOC08_RS24320	COG1187	pseudouridine synthase activity
FOC08_RS24330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC08_RS24330	COG1796	DNA polymerase
FOC08_RS24335	COG1286	toxin biosynthetic process
FOC08_RS24365	COG0017	Asparaginyl-tRNA synthetase
FOC08_RS24370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC08_RS24370	COG0072	phenylalanine-tRNA ligase activity
FOC08_RS24380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC08_RS24390	COG1418	mRNA catabolic process
FOC08_RS24415	COG2814	Major facilitator Superfamily
FOC08_RS24420	COG1566	PFAM secretion protein HlyD family protein
FOC08_RS24425	COG1309	transcriptional regulator
FOC08_RS24430	COG1363	Peptidase, m42
FOC08_RS24450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC08_RS24455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC08_RS24465	COG1484	DNA-dependent DNA replication
FOC08_RS24470	COG3611	Membrane attachment protein
FOC08_RS24480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC08_RS24490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC08_RS24495	COG0237	dephospho-CoA kinase activity
FOC08_RS24500	COG1971	Probably functions as a manganese efflux pump
FOC08_RS24505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC08_RS24510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC08_RS24510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC08_RS24515	COG5002	protein histidine kinase activity
FOC08_RS24520	COG0745	RESPONSE REGULATOR receiver
FOC08_RS24535	COG0538	isocitrate dehydrogenase activity
FOC08_RS24540	COG0372	Belongs to the citrate synthase family
FOC08_RS24550	COG0628	permease
FOC08_RS24555	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC08_RS24580	COG1725	Transcriptional regulator
FOC08_RS24585	COG0281	malic enzyme
FOC08_RS24590	COG0587	DNA-directed DNA polymerase activity
FOC08_RS24605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC08_RS24625	COG4109	DRTGG domain
FOC08_RS24640	COG0006	proline dipeptidase activity
FOC08_RS24675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS24680	COG0662	Cupin 2, conserved barrel domain protein
FOC08_RS24690	COG1476	TRANSCRIPTIONal
FOC08_RS24705	COG1028	Short-chain dehydrogenase reductase Sdr
FOC08_RS24710	COG0589	response to stress
FOC08_RS24750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS24770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC08_RS24775	COG0827	DNA restriction-modification system
FOC08_RS24780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC08_RS24785	COG3874	Sporulation protein YtfJ
FOC08_RS24795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC08_RS24800	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC08_RS24810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC08_RS24825	COG1104	cysteine desulfurase activity
FOC08_RS24835	COG0583	DNA-binding transcription factor activity
FOC08_RS24840	COG0697	spore germination
FOC08_RS24850	COG1956	GAF domain-containing protein
FOC08_RS24855	COG0626	cystathionine gamma-synthase activity
FOC08_RS24875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC08_RS24885	COG1595	DNA-templated transcription, initiation
FOC08_RS24900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC08_RS24905	COG0454	-acetyltransferase
FOC08_RS24910	COG0517	IMP dehydrogenase activity
FOC08_RS24915	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC08_RS24925	COG0745	RESPONSE REGULATOR receiver
FOC08_RS24935	COG0666	response to abiotic stimulus
FOC08_RS24970	COG1609	Transcriptional regulator
FOC08_RS24975	COG4851	CamS sex pheromone cAM373 precursor
FOC08_RS24980	COG3118	belongs to the thioredoxin family
FOC08_RS24990	COG2309	aminopeptidase activity
FOC08_RS25010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS25025	COG1674	ftsk spoiiie
FOC08_RS25035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC08_RS25040	COG4848	Belongs to the UPF0354 family
FOC08_RS25045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC08_RS25050	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC08_RS25055	COG1363	Peptidase, m42
FOC08_RS25065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS25080	COG0510	thiamine kinase activity
FOC08_RS25085	COG1523	belongs to the glycosyl hydrolase 13 family
FOC08_RS25100	COG1349	DNA-binding transcription factor activity
FOC08_RS25105	COG1187	pseudouridine synthase activity
FOC08_RS25110	COG2244	polysaccharide biosynthetic process
FOC08_RS25115	COG2081	HI0933 family
FOC08_RS25120	COG2814	Major facilitator Superfamily
FOC08_RS25130	COG3832	glyoxalase III activity
FOC08_RS25150	COG1329	Transcriptional regulator
FOC08_RS25160	COG4975	Glucose uptake
FOC08_RS25175	COG0314	molybdopterin synthase activity
FOC08_RS25180	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC08_RS25185	COG0303	'Molybdopterin
FOC08_RS25195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC08_RS25220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC08_RS25230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC08_RS25270	COG2814	Major facilitator Superfamily
FOC08_RS25275	COG0475	glutathione-regulated potassium exporter activity
FOC08_RS25280	COG0490	domain, Protein
FOC08_RS25285	COG0582	viral genome integration into host DNA
FOC08_RS25295	COG1136	(ABC) transporter
FOC08_RS25315	COG1242	4 iron, 4 sulfur cluster binding
FOC08_RS25320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC08_RS25325	COG1131	(ABC) transporter
FOC08_RS25335	COG1794	racemase activity, acting on amino acids and derivatives
FOC08_RS25355	COG2267	carboxylic ester hydrolase activity
FOC08_RS25360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC08_RS25365	COG0671	phosphoesterase, PA-phosphatase related
FOC08_RS25370	COG0438	transferase activity, transferring glycosyl groups
FOC08_RS25380	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC08_RS25430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC08_RS25435	COG5002	protein histidine kinase activity
FOC08_RS25440	COG4191	Histidine kinase
FOC08_RS25445	COG2267	carboxylic ester hydrolase activity
FOC08_RS25465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC08_RS25470	COG1116	anion transmembrane transporter activity
FOC08_RS25475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC08_RS25500	COG0494	nUDIX hydrolase
FOC08_RS25530	COG0288	reversible hydration of carbon dioxide
FOC08_RS25535	COG1271	oxidase subunit
FOC08_RS25540	COG1294	oxidase, subunit
FOC08_RS25560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS25585	COG1842	Phage shock protein A
FOC08_RS25620	COG5002	protein histidine kinase activity
FOC08_RS25625	COG0745	RESPONSE REGULATOR receiver
FOC08_RS25655	COG1597	lipid kinase activity
FOC08_RS25690	COG0586	Pfam SNARE associated Golgi protein
FOC08_RS25700	COG0577	efflux transmembrane transporter activity
FOC08_RS25705	COG1136	(ABC) transporter
FOC08_RS25710	COG3708	Transcriptional regulator
FOC08_RS25710	COG2207	Transcriptional regulator
FOC08_RS25715	COG0745	RESPONSE REGULATOR receiver
FOC08_RS25720	COG2205	protein histidine kinase activity
FOC08_RS25730	COG0577	efflux transmembrane transporter activity
FOC08_RS25735	COG1136	(ABC) transporter
FOC08_RS25775	COG3964	amidohydrolase
FOC08_RS25805	COG4948	Mandelate Racemase Muconate Lactonizing
FOC08_RS25815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC08_RS25820	COG0596	Alpha beta hydrolase
FOC08_RS25825	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC08_RS25830	COG1169	isochorismate synthase
FOC08_RS25835	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC08_RS25840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC08_RS25845	COG1278	Cold shock
FOC08_RS25860	COG0058	SHG alpha-glucan phosphorylase activity
FOC08_RS25865	COG0297	glycogen (starch) synthase activity
FOC08_RS25870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC08_RS25875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC08_RS25895	COG0039	L-malate dehydrogenase activity
FOC08_RS25990	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC08_RS26025	COG1285	pathogenesis
FOC08_RS26030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC08_RS26040	COG0166	Belongs to the GPI family
FOC08_RS26045	COG2155	Conserved Protein
FOC08_RS26050	COG1098	S1 RNA binding domain
FOC08_RS26055	COG0436	Aminotransferase
FOC08_RS26060	COG1522	sequence-specific DNA binding
FOC08_RS26065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC08_RS26070	COG2267	carboxylic ester hydrolase activity
FOC08_RS26080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC08_RS26095	COG5018	Exonuclease
FOC08_RS26100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC08_RS26115	COG0423	glycine-tRNA ligase activity
FOC08_RS26120	COG2050	protein possibly involved in aromatic compounds catabolism
FOC08_RS26130	COG1268	BioY protein
FOC08_RS26140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC08_RS26145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC08_RS26160	COG3584	3D domain protein
FOC08_RS26175	COG1252	NADH dehydrogenase
FOC08_RS26190	COG3708	Transcriptional regulator
FOC08_RS26205	COG1683	Conserved Protein
FOC08_RS26225	COG0316	Belongs to the HesB IscA family
FOC08_RS26240	COG1252	NADH dehydrogenase
FOC08_RS26255	COG0390	transport system, permease component
FOC08_RS26260	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC08_RS26300	COG4837	Protein of unknown function (DUF1462)
FOC08_RS26305	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC08_RS26315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC08_RS26320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC08_RS26330	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC08_RS26335	COG0647	UMP catabolic process
FOC08_RS26345	COG2445	Protein of unknown function DUF86
FOC08_RS26350	COG1494	fructose-1,6-bisphosphatase
FOC08_RS26365	COG4470	Protein conserved in bacteria
FOC08_RS26375	COG0789	Transcriptional regulator
FOC08_RS26380	COG4377	Putative membrane peptidase family (DUF2324)
FOC08_RS26405	COG0739	heme binding
FOC08_RS26415	COG3377	Domain of unknown function (DUF1805)
FOC08_RS26420	COG0737	Belongs to the 5'-nucleotidase family
FOC08_RS26425	COG1695	Transcriptional regulator
FOC08_RS26435	COG0719	Fe-S assembly protein
FOC08_RS26440	COG0822	iron-sulfur transferase activity
FOC08_RS26445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC08_RS26450	COG0719	Fe-S assembly protein
FOC08_RS26455	COG0396	ATPase activity
FOC08_RS26460	COG1464	Belongs to the NlpA lipoprotein family
FOC08_RS26465	COG1464	Belongs to the NlpA lipoprotein family
FOC08_RS26470	COG2011	ABC-type metal ion transport system permease component
FOC08_RS26475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC08_RS26485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC08_RS26490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC08_RS26505	COG1393	Belongs to the ArsC family
FOC08_RS26550	COG0039	L-malate dehydrogenase activity
FOC08_RS26570	COG1309	transcriptional regulator
FOC08_RS26575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC08_RS26580	COG1960	acyl-CoA dehydrogenase activity
FOC08_RS26585	COG0183	Belongs to the thiolase family
FOC08_RS26590	COG1024	Enoyl-CoA hydratase
FOC08_RS26590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC08_RS26600	COG1686	Belongs to the peptidase S11 family
FOC08_RS26615	COG0011	TIGRFAM Protein of
FOC08_RS26620	COG0840	transmembrane signaling receptor activity
FOC08_RS26635	COG2814	Major facilitator Superfamily
FOC08_RS26640	COG0531	amino acid
FOC08_RS26650	COG0706	membrane insertase activity
FOC08_RS26660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC08_RS26695	COG0586	Pfam SNARE associated Golgi protein
FOC08_RS26705	COG1376	ErfK ybiS ycfS ynhG family protein
FOC08_RS26710	COG0745	RESPONSE REGULATOR receiver
FOC08_RS26715	COG5002	protein histidine kinase activity
FOC08_RS26725	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC08_RS26740	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC08_RS26745	COG3227	Zinc metalloprotease (Elastase)
FOC08_RS26750	COG1741	Belongs to the pirin family
FOC08_RS26765	COG0475	glutathione-regulated potassium exporter activity
FOC08_RS26770	COG0490	domain, Protein
FOC08_RS26775	COG1115	amino acid carrier protein
FOC08_RS26780	COG0783	Belongs to the Dps family
FOC08_RS26795	COG1611	Belongs to the LOG family
FOC08_RS26815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS26820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC08_RS26825	COG1115	amino acid carrier protein
FOC08_RS26830	COG1115	amino acid carrier protein
FOC08_RS26835	COG2910	NAD(P)H-binding
FOC08_RS26850	COG0656	L-ascorbic acid biosynthetic process
FOC08_RS26855	COG2814	Major facilitator Superfamily
FOC08_RS26860	COG1733	regulation of RNA biosynthetic process
FOC08_RS26870	COG1252	NADH dehydrogenase
FOC08_RS26875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC08_RS26880	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC08_RS26890	COG0840	transmembrane signaling receptor activity
FOC08_RS26890	COG3290	protein histidine kinase activity
FOC08_RS26900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC08_RS26905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC08_RS26920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC08_RS26925	COG3223	Belongs to the PsiE family
FOC08_RS26975	COG0557	exoribonuclease II activity
FOC08_RS26980	COG1647	Serine aminopeptidase, S33
FOC08_RS26985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC08_RS26990	COG1346	cytolysis
FOC08_RS27080	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)