locus-tag	class	description
FOC09_RS00030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC09_RS00055	COG1686	Belongs to the peptidase S11 family
FOC09_RS00060	COG2318	DinB family
FOC09_RS00070	COG0572	uridine kinase
FOC09_RS00075	COG1247	-acetyltransferase
FOC09_RS00085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC09_RS00090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC09_RS00095	COG1024	Enoyl-CoA hydratase
FOC09_RS00100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC09_RS00105	COG0511	ligase activity, forming carbon-carbon bonds
FOC09_RS00110	COG0439	Biotin carboxylase
FOC09_RS00115	COG1960	acyl-CoA dehydrogenase activity
FOC09_RS00130	COG1309	transcriptional regulator
FOC09_RS00140	COG1131	(ABC) transporter
FOC09_RS00155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC09_RS00160	COG1252	NADH dehydrogenase
FOC09_RS00175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS00195	COG1309	transcriptional regulator
FOC09_RS00215	COG1876	peptidase activity
FOC09_RS00230	COG1476	TRANSCRIPTIONal
FOC09_RS00235	COG0457	Tetratricopeptide repeat
FOC09_RS00260	COG3718	enzyme involved in inositol metabolism
FOC09_RS00280	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS00290	COG0673	inositol 2-dehydrogenase activity
FOC09_RS00295	COG2814	Major facilitator Superfamily
FOC09_RS00300	COG1609	Transcriptional regulator
FOC09_RS00305	COG0671	phosphoesterase, PA-phosphatase related
FOC09_RS00310	COG2367	Beta-lactamase
FOC09_RS00320	COG0768	penicillin binding
FOC09_RS00330	COG1595	DNA-templated transcription, initiation
FOC09_RS00345	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC09_RS00375	COG1846	Transcriptional regulator
FOC09_RS00380	COG3961	Belongs to the TPP enzyme family
FOC09_RS00385	COG2226	methyltransferase
FOC09_RS00395	COG3615	Tellurite resistance protein tehB
FOC09_RS00395	COG0500	methyltransferase
FOC09_RS00400	COG1136	(ABC) transporter
FOC09_RS00400	COG0577	efflux transmembrane transporter activity
FOC09_RS00415	COG1309	transcriptional regulator
FOC09_RS00445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS00465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC09_RS00470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC09_RS00475	COG2971	BadF BadG BcrA BcrD
FOC09_RS00525	COG1595	DNA-templated transcription, initiation
FOC09_RS00555	COG1396	sequence-specific DNA binding
FOC09_RS00575	COG1132	(ABC) transporter
FOC09_RS00580	COG1132	(ABC) transporter
FOC09_RS00595	COG2258	MOSC domain
FOC09_RS00600	COG0583	DNA-binding transcription factor activity
FOC09_RS00615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC09_RS00620	COG0583	DNA-binding transcription factor activity
FOC09_RS00655	COG0561	phosphatase activity
FOC09_RS00660	COG0010	Belongs to the arginase family
FOC09_RS00675	COG1278	Cold shock
FOC09_RS00685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS00725	COG1247	-acetyltransferase
FOC09_RS00760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS00805	COG2226	methyltransferase
FOC09_RS00825	COG2814	Major facilitator Superfamily
FOC09_RS00830	COG0596	Alpha beta hydrolase
FOC09_RS00845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC09_RS00850	COG1187	pseudouridine synthase activity
FOC09_RS00855	COG2329	Antibiotic biosynthesis monooxygenase
FOC09_RS00870	COG1115	amino acid carrier protein
FOC09_RS00880	COG2318	DinB family
FOC09_RS00890	COG0776	regulation of translation
FOC09_RS00905	COG2814	Major facilitator Superfamily
FOC09_RS00910	COG3251	PFAM MbtH domain protein
FOC09_RS00915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC09_RS00920	COG1535	isochorismatase
FOC09_RS00920	COG3433	isochorismatase activity
FOC09_RS00925	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC09_RS00930	COG1169	isochorismate synthase
FOC09_RS00935	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS00940	COG2223	nitrite transmembrane transporter activity
FOC09_RS00960	COG0419	ATPase involved in DNA repair
FOC09_RS00965	COG0420	3'-5' exonuclease activity
FOC09_RS00980	COG1024	Enoyl-CoA hydratase
FOC09_RS00985	COG1280	lysine exporter protein (LysE YggA)
FOC09_RS00990	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS00995	COG2084	Dehydrogenase
FOC09_RS01000	COG1960	acyl-CoA dehydrogenase activity
FOC09_RS01005	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC09_RS01010	COG2079	MmgE PrpD family protein
FOC09_RS01015	COG0372	Belongs to the citrate synthase family
FOC09_RS01020	COG4841	protein insertion into membrane
FOC09_RS01025	COG2814	Major facilitator Superfamily
FOC09_RS01030	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC09_RS01030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC09_RS01070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC09_RS01160	COG1715	Restriction endonuclease
FOC09_RS01160	COG1787	Restriction endonuclease
FOC09_RS01190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC09_RS01195	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC09_RS01200	COG0671	phosphoesterase, PA-phosphatase related
FOC09_RS01205	COG4326	sporulation control protein
FOC09_RS01245	COG1509	lysine 2,3-aminomutase activity
FOC09_RS01250	COG3829	transcription factor binding
FOC09_RS01255	COG0456	acetyltransferase
FOC09_RS01260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC09_RS01265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC09_RS01270	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC09_RS01275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC09_RS01290	COG5506	Protein of unknown function (DUF1694)
FOC09_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS01300	COG1253	flavin adenine dinucleotide binding
FOC09_RS01335	COG1174	glycine betaine transport
FOC09_RS01340	COG1125	glycine betaine transport
FOC09_RS01340	COG0517	IMP dehydrogenase activity
FOC09_RS01370	COG1070	Carbohydrate kinase
FOC09_RS01395	COG1064	alcohol dehydrogenase
FOC09_RS01405	COG2197	response regulator
FOC09_RS01410	COG4585	Histidine kinase
FOC09_RS01410	COG2203	Gaf domain
FOC09_RS01415	COG0668	transmembrane transport
FOC09_RS01425	COG1051	belongs to the nudix hydrolase family
FOC09_RS01450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC09_RS01455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS01470	COG0367	asparagine synthase
FOC09_RS01475	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC09_RS01480	COG1999	signal sequence binding
FOC09_RS01485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC09_RS01490	COG1307	EDD domain protein, DegV family
FOC09_RS01500	COG0805	protein transport
FOC09_RS01510	COG1272	protein, Hemolysin III
FOC09_RS01515	COG0204	Acyl-transferase
FOC09_RS01520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC09_RS01525	COG0768	penicillin binding
FOC09_RS01540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC09_RS01560	COG0546	phosphoglycolate phosphatase activity
FOC09_RS01575	COG1131	(ABC) transporter
FOC09_RS01590	COG0456	acetyltransferase
FOC09_RS01600	COG1794	racemase activity, acting on amino acids and derivatives
FOC09_RS01605	COG1454	alcohol dehydrogenase
FOC09_RS01610	COG2610	gluconate transmembrane transporter activity
FOC09_RS01635	COG0733	neurotransmitter:sodium symporter activity
FOC09_RS01650	COG5002	protein histidine kinase activity
FOC09_RS01650	COG3850	Histidine kinase
FOC09_RS01655	COG0745	RESPONSE REGULATOR receiver
FOC09_RS01660	COG0471	metal ion transport
FOC09_RS01665	COG1929	Belongs to the glycerate kinase type-1 family
FOC09_RS01735	COG1674	ftsk spoiiie
FOC09_RS01755	COG0017	Asparaginyl-tRNA synthetase
FOC09_RS01775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC09_RS01800	COG0018	arginyl-trna synthetase
FOC09_RS01805	COG2521	methyltransferase
FOC09_RS01805	COG2136	Putative SAM-dependent methyltransferase
FOC09_RS01820	COG1413	lyase activity
FOC09_RS01835	COG0629	single-stranded DNA binding
FOC09_RS01850	COG0488	(ABC) transporter
FOC09_RS01855	COG1418	mRNA catabolic process
FOC09_RS01870	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS01885	COG2359	stage V sporulation protein S
FOC09_RS01920	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC09_RS01925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC09_RS01930	COG2146	nitrite reductase [NAD(P)H] activity
FOC09_RS01935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC09_RS01935	COG1587	Uroporphyrinogen-III synthase
FOC09_RS01945	COG1648	precorrin-2 dehydrogenase activity
FOC09_RS01960	COG2223	nitrite transmembrane transporter activity
FOC09_RS01970	COG0314	molybdopterin synthase activity
FOC09_RS01975	COG0303	'Molybdopterin
FOC09_RS01980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC09_RS01985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC09_RS01990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC09_RS02010	COG2181	nitrate reductase activity
FOC09_RS02015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC09_RS02020	COG1140	nitrate reductase beta subunit
FOC09_RS02025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC09_RS02040	COG0714	Associated with various cellular activities
FOC09_RS02045	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC09_RS02050	COG1305	Transglutaminase-like
FOC09_RS02055	COG0386	Belongs to the glutathione peroxidase family
FOC09_RS02080	COG1595	DNA-templated transcription, initiation
FOC09_RS02085	COG0604	alcohol dehydrogenase
FOC09_RS02095	COG0346	lactoylglutathione lyase activity
FOC09_RS02120	COG2226	methyltransferase
FOC09_RS02145	COG3874	Sporulation protein YtfJ
FOC09_RS02195	COG0456	acetyltransferase
FOC09_RS02220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS02225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS02230	COG1819	glycosyl
FOC09_RS02250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC09_RS02260	COG0561	phosphatase activity
FOC09_RS02280	COG2211	Major facilitator Superfamily
FOC09_RS02285	COG0154	amidase activity
FOC09_RS02295	COG1876	peptidase activity
FOC09_RS02305	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS02325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC09_RS02330	COG1114	Component of the transport system for branched-chain amino acids
FOC09_RS02345	COG1253	flavin adenine dinucleotide binding
FOC09_RS02350	COG2839	Protein conserved in bacteria
FOC09_RS02355	COG0702	epimerase
FOC09_RS02370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC09_RS02380	COG1607	acyl-coa hydrolase
FOC09_RS02385	COG3689	TIGRFAM TIGR03943 family protein
FOC09_RS02390	COG0701	Predicted permease
FOC09_RS02400	COG2244	polysaccharide biosynthetic process
FOC09_RS02405	COG0586	Pfam SNARE associated Golgi protein
FOC09_RS02410	COG1051	belongs to the nudix hydrolase family
FOC09_RS02415	COG5337	Spore coat protein CotH
FOC09_RS02425	COG0406	alpha-ribazole phosphatase activity
FOC09_RS02440	COG4166	transmembrane transport
FOC09_RS02450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC09_RS02460	COG0702	epimerase
FOC09_RS02465	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC09_RS02465	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC09_RS02515	COG0456	acetyltransferase
FOC09_RS02520	COG0523	cobalamin synthesis protein
FOC09_RS02525	COG4989	oxidoreductase activity
FOC09_RS02535	COG1231	oxidoreductase activity
FOC09_RS02545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC09_RS02560	COG0783	Belongs to the Dps family
FOC09_RS02565	COG3949	Membrane
FOC09_RS02580	COG0840	transmembrane signaling receptor activity
FOC09_RS02605	COG2814	Major facilitator Superfamily
FOC09_RS02610	COG0667	Aldo Keto reductase
FOC09_RS02615	COG0640	Transcriptional regulator
FOC09_RS02620	COG1404	Belongs to the peptidase S8 family
FOC09_RS02625	COG2002	toxin-antitoxin pair type II binding
FOC09_RS02665	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC09_RS02675	COG1279	arginine transmembrane transporter activity
FOC09_RS02690	COG1082	Xylose isomerase domain protein TIM barrel
FOC09_RS02705	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS02710	COG4264	IucA IucC family
FOC09_RS02720	COG1247	-acetyltransferase
FOC09_RS02725	COG1285	pathogenesis
FOC09_RS02735	COG0726	polysaccharide deacetylase
FOC09_RS02740	COG5002	protein histidine kinase activity
FOC09_RS02745	COG0745	RESPONSE REGULATOR receiver
FOC09_RS02755	COG1316	TRANSCRIPTIONal
FOC09_RS02780	COG0460	homoserine dehydrogenase
FOC09_RS02800	COG0726	polysaccharide deacetylase
FOC09_RS02815	COG0300	oxidoreductase activity
FOC09_RS02825	COG5002	protein histidine kinase activity
FOC09_RS02830	COG0745	RESPONSE REGULATOR receiver
FOC09_RS02845	COG0791	NLP P60 protein
FOC09_RS02845	COG1388	LysM domain
FOC09_RS02860	COG1686	Belongs to the peptidase S11 family
FOC09_RS02880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC09_RS02885	COG4988	ABC transporter
FOC09_RS02890	COG1294	oxidase, subunit
FOC09_RS02895	COG1271	oxidase subunit
FOC09_RS02905	COG1846	Transcriptional regulator
FOC09_RS02915	COG1942	4-Oxalocrotonate Tautomerase
FOC09_RS02925	COG0583	DNA-binding transcription factor activity
FOC09_RS02945	COG0411	ABC transporter
FOC09_RS02955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC09_RS02960	COG2030	dehydratase
FOC09_RS02965	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS02980	COG0523	cobalamin synthesis protein
FOC09_RS02985	COG1231	oxidoreductase activity
FOC09_RS02990	COG0039	L-malate dehydrogenase activity
FOC09_RS02995	COG0628	permease
FOC09_RS03005	COG0778	Nitroreductase
FOC09_RS03010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC09_RS03015	COG1959	2 iron, 2 sulfur cluster binding
FOC09_RS03020	COG0583	DNA-binding transcription factor activity
FOC09_RS03025	COG0697	spore germination
FOC09_RS03035	COG4549	nuclear export factor GLE1
FOC09_RS03040	COG2372	response to copper ion
FOC09_RS03040	COG1276	copper resistance
FOC09_RS03055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC09_RS03085	COG2132	Multicopper oxidase
FOC09_RS03090	COG0006	proline dipeptidase activity
FOC09_RS03110	COG4224	UPF0291 protein
FOC09_RS03125	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC09_RS03130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS03140	COG2390	Transcriptional regulator
FOC09_RS03170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC09_RS03185	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC09_RS03205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS03240	COG1073	alpha beta
FOC09_RS03260	COG0427	acetyl-CoA hydrolase
FOC09_RS03265	COG3279	Response regulator of the LytR AlgR family
FOC09_RS03275	COG3384	dioxygenase
FOC09_RS03280	COG2814	Major facilitator Superfamily
FOC09_RS03305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC09_RS03315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC09_RS03320	COG0440	acetolactate synthase activity
FOC09_RS03325	COG0028	Belongs to the TPP enzyme family
FOC09_RS03330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC09_RS03340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC09_RS03355	COG2084	Dehydrogenase
FOC09_RS03370	COG2323	membrane
FOC09_RS03375	COG5566	PFAM Mor transcription activator
FOC09_RS03385	COG0733	neurotransmitter:sodium symporter activity
FOC09_RS03390	COG2244	polysaccharide biosynthetic process
FOC09_RS03405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC09_RS03410	COG2223	nitrite transmembrane transporter activity
FOC09_RS03420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC09_RS03430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC09_RS03445	COG1966	Carbon starvation protein
FOC09_RS03470	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS03475	COG1051	belongs to the nudix hydrolase family
FOC09_RS03525	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC09_RS03530	COG0784	Response regulator, receiver
FOC09_RS03535	COG4191	Histidine kinase
FOC09_RS03540	COG0281	malic enzyme
FOC09_RS03545	COG1027	Aspartate ammonia-lyase
FOC09_RS03555	COG0528	UMP kinase activity
FOC09_RS03560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC09_RS03575	COG1131	(ABC) transporter
FOC09_RS03610	COG2733	membrane
FOC09_RS03640	COG0785	Cytochrome C biogenesis protein
FOC09_RS03660	COG3340	Belongs to the peptidase S51 family
FOC09_RS03685	COG0114	fumarate hydratase activity
FOC09_RS03690	COG1757	Na H antiporter
FOC09_RS03695	COG1216	Glycosyl transferase, family 2
FOC09_RS03695	COG0438	transferase activity, transferring glycosyl groups
FOC09_RS03705	COG0701	Predicted permease
FOC09_RS03710	COG0523	cobalamin synthesis protein
FOC09_RS03715	COG0697	spore germination
FOC09_RS03720	COG1802	Transcriptional regulator
FOC09_RS03750	COG0367	asparagine synthase
FOC09_RS03780	COG0406	alpha-ribazole phosphatase activity
FOC09_RS03790	COG1686	Belongs to the peptidase S11 family
FOC09_RS03820	COG1234	tRNA 3'-trailer cleavage
FOC09_RS03825	COG1177	transmembrane transport
FOC09_RS03830	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC09_RS03835	COG3842	ATPase activity
FOC09_RS03865	COG2329	Antibiotic biosynthesis monooxygenase
FOC09_RS03885	COG1309	transcriptional regulator
FOC09_RS03910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC09_RS03915	COG4786	Flagellar basal body rod
FOC09_RS03925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC09_RS03930	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC09_RS03940	COG1987	bacterial-type flagellum assembly
FOC09_RS03945	COG1338	Plays a role in the flagellum-specific transport system
FOC09_RS03955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC09_RS03955	COG1776	CheC inhibitor of MCP methylation
FOC09_RS03970	COG0741	lytic transglycosylase activity
FOC09_RS03975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC09_RS04010	COG0463	Glycosyl transferase, family 2
FOC09_RS04060	COG1157	protein secretion by the type III secretion system
FOC09_RS04070	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC09_RS04080	COG1677	Flagellar hook-basal body complex protein FliE
FOC09_RS04085	COG1558	bacterial-type flagellum-dependent cell motility
FOC09_RS04090	COG1815	bacterial-type flagellum-dependent cell motility
FOC09_RS04115	COG1256	bacterial-type flagellum assembly
FOC09_RS04135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC09_RS04150	COG1776	CheC inhibitor of MCP methylation
FOC09_RS04150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC09_RS04160	COG2201	protein-glutamate methylesterase activity
FOC09_RS04165	COG1360	Flagellar Motor Protein
FOC09_RS04170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC09_RS04180	COG1923	regulation of RNA biosynthetic process
FOC09_RS04235	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC09_RS04240	COG2323	membrane
FOC09_RS04250	COG0789	Transcriptional regulator
FOC09_RS04250	COG4978	Transcriptional regulator
FOC09_RS04260	COG0475	glutathione-regulated potassium exporter activity
FOC09_RS04270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC09_RS04275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC09_RS04280	COG3162	membrane
FOC09_RS04295	COG1280	lysine exporter protein (LysE YggA)
FOC09_RS04335	COG0328	RNA-DNA hybrid ribonuclease activity
FOC09_RS04355	COG0454	-acetyltransferase
FOC09_RS04375	COG1215	transferase activity, transferring glycosyl groups
FOC09_RS04390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC09_RS04415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC09_RS04465	COG0456	acetyltransferase
FOC09_RS04475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC09_RS04480	COG2311	Membrane
FOC09_RS04485	COG2233	PERMEase
FOC09_RS04500	COG0024	Methionine aminopeptidase
FOC09_RS04505	COG3173	Aminoglycoside phosphotransferase
FOC09_RS04515	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC09_RS04520	COG1199	ATP-dependent helicase activity
FOC09_RS04530	COG0116	Belongs to the methyltransferase superfamily
FOC09_RS04545	COG4474	Belongs to the UPF0398 family
FOC09_RS04585	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC09_RS04585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC09_RS04595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC09_RS04600	COG3935	DnaD domain protein
FOC09_RS04620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC09_RS04620	COG1199	ATP-dependent helicase activity
FOC09_RS04655	COG0438	transferase activity, transferring glycosyl groups
FOC09_RS04660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC09_RS04675	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC09_RS04680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS04690	COG2738	Putative neutral zinc metallopeptidase
FOC09_RS04705	COG4347	Protein of unknown function (DUF1405)
FOC09_RS04715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC09_RS04735	COG0457	Tetratricopeptide repeat
FOC09_RS04740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC09_RS04755	COG0105	UTP biosynthetic process
FOC09_RS04760	COG0142	geranyltranstransferase activity
FOC09_RS04770	COG0142	geranyltranstransferase activity
FOC09_RS04785	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC09_RS04860	COG0492	ferredoxin-NADP+ reductase activity
FOC09_RS04880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC09_RS04885	COG4862	establishment of competence for transformation
FOC09_RS04905	COG1266	CAAX protease self-immunity
FOC09_RS04910	COG0514	ATP-dependent DNA helicase (RecQ)
FOC09_RS04915	COG4955	Helix-turn-helix domain
FOC09_RS04920	COG1141	Ferredoxin
FOC09_RS04925	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC09_RS04940	COG2096	Adenosyltransferase
FOC09_RS04945	COG5002	protein histidine kinase activity
FOC09_RS04950	COG0745	RESPONSE REGULATOR receiver
FOC09_RS04955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC09_RS04960	COG1333	cytochrome c biogenesis protein
FOC09_RS04970	COG1187	pseudouridine synthase activity
FOC09_RS04975	COG0700	Nucleoside recognition
FOC09_RS04980	COG2715	membrane protein required for spore maturation
FOC09_RS04985	COG1686	Belongs to the peptidase S11 family
FOC09_RS04990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC09_RS05005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC09_RS05005	COG0392	lysyltransferase activity
FOC09_RS05025	COG5002	protein histidine kinase activity
FOC09_RS05030	COG0582	viral genome integration into host DNA
FOC09_RS05040	COG1801	Protein of unknown function DUF72
FOC09_RS05060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC09_RS05065	COG1392	Phosphate transport regulator
FOC09_RS05070	COG0306	phosphate transporter
FOC09_RS05075	COG0730	response to heat
FOC09_RS05090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC09_RS05090	COG1017	nitric oxide dioxygenase activity
FOC09_RS05115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC09_RS05125	COG1114	Component of the transport system for branched-chain amino acids
FOC09_RS05135	COG2197	response regulator
FOC09_RS05140	COG4585	Histidine kinase
FOC09_RS05145	COG4758	membrane
FOC09_RS05160	COG1757	Na H antiporter
FOC09_RS05180	COG0733	neurotransmitter:sodium symporter activity
FOC09_RS05185	COG1648	precorrin-2 dehydrogenase activity
FOC09_RS05205	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC09_RS05210	COG0529	Catalyzes the synthesis of activated sulfate
FOC09_RS05230	COG0019	diaminopimelate decarboxylase activity
FOC09_RS05240	COG1368	sulfuric ester hydrolase activity
FOC09_RS05245	COG1183	phosphatidylcholine synthase activity
FOC09_RS05260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC09_RS05295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC09_RS05320	COG0473	3-isopropylmalate dehydrogenase activity
FOC09_RS05330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC09_RS05335	COG0440	acetolactate synthase activity
FOC09_RS05340	COG0028	Belongs to the TPP enzyme family
FOC09_RS05345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC09_RS05370	COG3874	Sporulation protein YtfJ
FOC09_RS05375	COG4709	membrane
FOC09_RS05380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC09_RS05385	COG1301	dicarboxylic acid transport
FOC09_RS05395	COG1846	Transcriptional regulator
FOC09_RS05410	COG1968	undecaprenyl-diphosphatase activity
FOC09_RS05415	COG0534	Mate efflux family protein
FOC09_RS05430	COG3173	Aminoglycoside phosphotransferase
FOC09_RS05440	COG0716	FMN binding
FOC09_RS05460	COG1696	Membrane protein involved in D-alanine export
FOC09_RS05470	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC09_RS05475	COG2070	2-Nitropropane dioxygenase
FOC09_RS05480	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC09_RS05490	COG1335	isochorismatase
FOC09_RS05500	COG1522	sequence-specific DNA binding
FOC09_RS05515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC09_RS05520	COG1131	(ABC) transporter
FOC09_RS05530	COG1131	(ABC) transporter
FOC09_RS05535	COG1725	Transcriptional regulator
FOC09_RS05540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC09_RS05560	COG1780	Probably involved in ribonucleotide reductase function
FOC09_RS05585	COG4873	Protein conserved in bacteria
FOC09_RS05600	COG0720	synthase
FOC09_RS05610	COG5002	protein histidine kinase activity
FOC09_RS05615	COG2318	DinB family
FOC09_RS05625	COG1846	Transcriptional regulator
FOC09_RS05630	COG3852	Histidine kinase
FOC09_RS05640	COG2861	carbohydrate metabolic process
FOC09_RS05660	COG1349	DNA-binding transcription factor activity
FOC09_RS05675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC09_RS05690	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC09_RS05700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC09_RS05710	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC09_RS05715	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS05735	COG2030	dehydratase
FOC09_RS05745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC09_RS05750	COG0861	Integral membrane protein TerC family
FOC09_RS05755	COG2116	formate transmembrane transporter activity
FOC09_RS05765	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC09_RS05785	COG2186	Transcriptional regulator
FOC09_RS05790	COG5002	protein histidine kinase activity
FOC09_RS05795	COG0745	RESPONSE REGULATOR receiver
FOC09_RS05805	COG3835	regulator
FOC09_RS05810	COG0277	FAD linked oxidase domain protein
FOC09_RS05815	COG0247	lactate metabolic process
FOC09_RS05820	COG2340	Cysteine-rich secretory protein family
FOC09_RS05830	COG0564	pseudouridine synthase activity
FOC09_RS05840	COG2409	Drug exporters of the RND superfamily
FOC09_RS05850	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC09_RS05855	COG1177	transmembrane transport
FOC09_RS05860	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC09_RS05865	COG3842	ATPase activity
FOC09_RS05870	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS05905	COG0681	Belongs to the peptidase S26 family
FOC09_RS05910	COG1686	Belongs to the peptidase S11 family
FOC09_RS05920	COG2226	methyltransferase
FOC09_RS05980	COG1476	TRANSCRIPTIONal
FOC09_RS05990	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC09_RS06045	COG5634	Uncharacterized conserved protein (DUF2278)
FOC09_RS06050	COG1620	l-lactate permease
FOC09_RS06085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC09_RS06085	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC09_RS06095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC09_RS06100	COG5492	domain, Protein
FOC09_RS06115	COG2382	esterase
FOC09_RS06120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC09_RS06125	COG2153	protein acetylation
FOC09_RS06170	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC09_RS06185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC09_RS06205	COG0457	Tetratricopeptide repeat
FOC09_RS06205	COG0463	Glycosyl transferase, family 2
FOC09_RS06225	COG1216	Glycosyl transferase, family 2
FOC09_RS06245	COG0564	pseudouridine synthase activity
FOC09_RS06250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC09_RS06255	COG2357	RelA SpoT domain protein
FOC09_RS06265	COG4116	CYTH
FOC09_RS06270	COG2346	COG2346, Truncated hemoglobins
FOC09_RS06280	COG1164	Oligoendopeptidase f
FOC09_RS06290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC09_RS06295	COG4862	establishment of competence for transformation
FOC09_RS06300	COG0861	Integral membrane protein TerC family
FOC09_RS06305	COG1393	Belongs to the ArsC family
FOC09_RS06315	COG4166	transmembrane transport
FOC09_RS06320	COG0534	Mate efflux family protein
FOC09_RS06325	COG4608	Belongs to the ABC transporter superfamily
FOC09_RS06330	COG0444	Belongs to the ABC transporter superfamily
FOC09_RS06335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC09_RS06340	COG0601	transmembrane transport
FOC09_RS06345	COG4166	transmembrane transport
FOC09_RS06355	COG0180	Tryptophanyl-tRNA synthetase
FOC09_RS06365	COG5504	Zn-dependent protease
FOC09_RS06370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC09_RS06375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC09_RS06390	COG2267	carboxylic ester hydrolase activity
FOC09_RS06400	COG0542	response to heat
FOC09_RS06410	COG0561	phosphatase activity
FOC09_RS06425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS06435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC09_RS06445	COG2996	Protein conserved in bacteria
FOC09_RS06470	COG0753	catalase activity
FOC09_RS06480	COG0367	asparagine synthase
FOC09_RS06505	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC09_RS06550	COG1074	ATP-dependent DNA helicase activity
FOC09_RS06555	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC09_RS06565	COG0398	Pfam SNARE associated Golgi protein
FOC09_RS06570	COG4903	ComK protein
FOC09_RS06585	COG1278	Cold shock
FOC09_RS06595	COG2224	Isocitrate lyase
FOC09_RS06600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC09_RS06605	COG0497	DNA recombination
FOC09_RS06620	COG0697	spore germination
FOC09_RS06625	COG0840	transmembrane signaling receptor activity
FOC09_RS06630	COG0501	Belongs to the peptidase M48B family
FOC09_RS06655	COG0745	RESPONSE REGULATOR receiver
FOC09_RS06660	COG2205	protein histidine kinase activity
FOC09_RS06670	COG3708	Transcriptional regulator
FOC09_RS06670	COG2207	Transcriptional regulator
FOC09_RS06675	COG1595	DNA-templated transcription, initiation
FOC09_RS06685	COG1078	dGTPase activity
FOC09_RS06720	COG3209	COG3209 Rhs family protein
FOC09_RS06750	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS06760	COG0095	Lipoate-protein ligase
FOC09_RS06765	COG1234	tRNA 3'-trailer cleavage
FOC09_RS06775	COG1609	Transcriptional regulator
FOC09_RS06800	COG1511	domain protein
FOC09_RS06805	COG1309	transcriptional regulator
FOC09_RS06850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC09_RS06855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC09_RS06860	COG2329	Antibiotic biosynthesis monooxygenase
FOC09_RS06865	COG3428	Bacterial PH domain
FOC09_RS06870	COG3402	PFAM membrane-flanked domain
FOC09_RS06915	COG3402	PFAM membrane-flanked domain
FOC09_RS06920	COG1309	transcriptional regulator
FOC09_RS06935	COG4473	ABC transporter
FOC09_RS06940	COG1131	(ABC) transporter
FOC09_RS06945	COG0537	adenosine 5'-monophosphoramidase activity
FOC09_RS06950	COG4980	gas vesicle protein
FOC09_RS06970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC09_RS06975	COG3973	AAA domain
FOC09_RS06985	COG0477	Major facilitator Superfamily
FOC09_RS06990	COG0477	Major facilitator Superfamily
FOC09_RS07025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC09_RS07035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC09_RS07040	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC09_RS07060	COG2267	carboxylic ester hydrolase activity
FOC09_RS07065	COG0457	Tetratricopeptide repeat
FOC09_RS07070	COG0346	lactoylglutathione lyase activity
FOC09_RS07075	COG0346	lactoylglutathione lyase activity
FOC09_RS07080	COG2814	Major facilitator Superfamily
FOC09_RS07085	COG1309	transcriptional regulator
FOC09_RS07110	COG0420	3'-5' exonuclease activity
FOC09_RS07140	COG0393	Putative heavy-metal-binding
FOC09_RS07160	COG0784	Response regulator, receiver
FOC09_RS07160	COG2205	protein histidine kinase activity
FOC09_RS07160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC09_RS07160	COG2198	Histidine kinase
FOC09_RS07165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC09_RS07170	COG2208	phosphoserine phosphatase activity
FOC09_RS07180	COG1191	sigma factor activity
FOC09_RS07205	COG3237	CsbD-like
FOC09_RS07255	COG2770	Histidine kinase
FOC09_RS07255	COG3437	response regulator, receiver
FOC09_RS07285	COG1959	2 iron, 2 sulfur cluster binding
FOC09_RS07290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC09_RS07295	COG2376	Dihydroxyacetone kinase
FOC09_RS07305	COG2376	Dihydroxyacetone kinase
FOC09_RS07325	COG1183	phosphatidylcholine synthase activity
FOC09_RS07350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC09_RS07350	COG3320	Male sterility
FOC09_RS07395	COG0477	Major facilitator Superfamily
FOC09_RS07425	COG0305	Participates in initiation and elongation during chromosome replication
FOC09_RS07440	COG0789	Transcriptional regulator
FOC09_RS07440	COG4978	Transcriptional regulator
FOC09_RS07470	COG3181	Tripartite tricarboxylate transporter family receptor
FOC09_RS07475	COG4565	transcriptional regulatory protein
FOC09_RS07480	COG3290	protein histidine kinase activity
FOC09_RS07485	COG0477	Major facilitator Superfamily
FOC09_RS07515	COG0322	excinuclease ABC activity
FOC09_RS07520	COG4608	Belongs to the ABC transporter superfamily
FOC09_RS07530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC09_RS07535	COG0601	transmembrane transport
FOC09_RS07570	COG3938	Belongs to the proline racemase family
FOC09_RS07590	COG1363	Peptidase, m42
FOC09_RS07610	COG1024	Enoyl-CoA hydratase
FOC09_RS07625	COG1696	Membrane protein involved in D-alanine export
FOC09_RS07640	COG4196	transglutaminase domain protein
FOC09_RS07645	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS07655	COG2244	polysaccharide biosynthetic process
FOC09_RS07660	COG0653	protein targeting
FOC09_RS07680	COG0659	secondary active sulfate transmembrane transporter activity
FOC09_RS07695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC09_RS07710	COG0561	phosphatase activity
FOC09_RS07725	COG3527	Alpha-acetolactate decarboxylase
FOC09_RS07730	COG0028	Belongs to the TPP enzyme family
FOC09_RS07760	COG0189	ligase activity
FOC09_RS07775	COG1126	abc transporter atp-binding protein
FOC09_RS07780	COG0765	amino acid transport
FOC09_RS07785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC09_RS07795	COG1132	(ABC) transporter
FOC09_RS07800	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS07810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC09_RS07815	COG0531	amino acid
FOC09_RS07825	COG0693	protein deglycase activity
FOC09_RS07825	COG0753	catalase activity
FOC09_RS07830	COG0693	protein deglycase activity
FOC09_RS07840	COG2211	Major facilitator Superfamily
FOC09_RS07845	COG4533	DNA binding
FOC09_RS07850	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC09_RS07860	COG1733	regulation of RNA biosynthetic process
FOC09_RS07865	COG2814	Major facilitator Superfamily
FOC09_RS07870	COG1309	transcriptional regulator
FOC09_RS07875	COG2076	Multidrug Resistance protein
FOC09_RS07880	COG2076	Multidrug Resistance protein
FOC09_RS07890	COG1522	sequence-specific DNA binding
FOC09_RS07895	COG0697	spore germination
FOC09_RS07910	COG2259	Doxx family
FOC09_RS07920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC09_RS07920	COG1263	PTS System
FOC09_RS07930	COG1737	Transcriptional regulator
FOC09_RS07940	COG0475	glutathione-regulated potassium exporter activity
FOC09_RS07945	COG0531	amino acid
FOC09_RS07975	COG0586	Pfam SNARE associated Golgi protein
FOC09_RS08010	COG3546	catalase activity
FOC09_RS08015	COG1114	Component of the transport system for branched-chain amino acids
FOC09_RS08030	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC09_RS08040	COG1136	(ABC) transporter
FOC09_RS08045	COG0577	efflux transmembrane transporter activity
FOC09_RS08050	COG3584	3D domain protein
FOC09_RS08050	COG1388	LysM domain
FOC09_RS08070	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC09_RS08075	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC09_RS08080	COG3711	transcriptional antiterminator
FOC09_RS08080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC09_RS08095	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC09_RS08100	COG0604	alcohol dehydrogenase
FOC09_RS08105	COG1316	TRANSCRIPTIONal
FOC09_RS08115	COG0730	response to heat
FOC09_RS08120	COG2210	Belongs to the sulfur carrier protein TusA family
FOC09_RS08130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC09_RS08135	COG0425	Belongs to the sulfur carrier protein TusA family
FOC09_RS08140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC09_RS08140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS08145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC09_RS08145	COG0425	Belongs to the sulfur carrier protein TusA family
FOC09_RS08150	COG1937	Protein conserved in bacteria
FOC09_RS08155	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC09_RS08180	COG2719	SpoVR family
FOC09_RS08185	COG0778	Nitroreductase
FOC09_RS08220	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC09_RS08225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC09_RS08235	COG1609	Transcriptional regulator
FOC09_RS08240	COG1263	PTS System
FOC09_RS08240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC09_RS08245	COG1621	beta-fructofuranosidase activity
FOC09_RS08250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC09_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS08270	COG2252	PERMEase
FOC09_RS08285	COG1846	Transcriptional regulator
FOC09_RS08290	COG2814	Major facilitator Superfamily
FOC09_RS08295	COG2205	protein histidine kinase activity
FOC09_RS08335	COG0351	phosphomethylpyrimidine kinase
FOC09_RS08340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC09_RS08350	COG2104	thiamine diphosphate biosynthetic process
FOC09_RS08355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC09_RS08360	COG0352	thiamine-phosphate diphosphorylase activity
FOC09_RS08365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC09_RS08370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC09_RS08375	COG1116	anion transmembrane transporter activity
FOC09_RS08380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC09_RS08400	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC09_RS08515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC09_RS08525	COG0581	inorganic phosphate transmembrane transporter activity
FOC09_RS08530	COG0573	inorganic phosphate transmembrane transporter activity
FOC09_RS08535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC09_RS08540	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC09_RS08540	COG1918	ferrous iron import across plasma membrane
FOC09_RS08545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC09_RS08550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC09_RS08560	COG0531	amino acid
FOC09_RS08565	COG0697	spore germination
FOC09_RS08570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC09_RS08585	COG4990	cell redox homeostasis
FOC09_RS08590	COG0833	amino acid
FOC09_RS08595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC09_RS08600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC09_RS08615	COG0475	glutathione-regulated potassium exporter activity
FOC09_RS08615	COG0569	domain protein
FOC09_RS08640	COG2252	PERMEase
FOC09_RS08645	COG1113	amino acid transport
FOC09_RS08660	COG1114	Component of the transport system for branched-chain amino acids
FOC09_RS08665	COG3104	oligopeptide transport
FOC09_RS08680	COG1476	TRANSCRIPTIONal
FOC09_RS08685	COG1388	LysM domain
FOC09_RS08685	COG3584	3D domain protein
FOC09_RS08690	COG0840	transmembrane signaling receptor activity
FOC09_RS08695	COG1968	undecaprenyl-diphosphatase activity
FOC09_RS08720	COG3568	Endonuclease Exonuclease Phosphatase
FOC09_RS08735	COG1063	alcohol dehydrogenase
FOC09_RS08755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC09_RS08760	COG1879	ABC-type sugar transport system periplasmic component
FOC09_RS08765	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC09_RS08770	COG1129	ABC transporter
FOC09_RS08780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC09_RS08785	COG1609	Transcriptional regulator
FOC09_RS08795	COG1846	Transcriptional regulator
FOC09_RS08800	COG2271	Major facilitator Superfamily
FOC09_RS08810	COG4608	Belongs to the ABC transporter superfamily
FOC09_RS08815	COG0601	transmembrane transport
FOC09_RS08825	COG0747	negative chemotaxis
FOC09_RS08840	COG0659	secondary active sulfate transmembrane transporter activity
FOC09_RS08855	COG5002	protein histidine kinase activity
FOC09_RS08860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC09_RS08865	COG2378	regulation of single-species biofilm formation
FOC09_RS08890	COG0833	amino acid
FOC09_RS08895	COG0765	amino acid transport
FOC09_RS08900	COG0765	amino acid transport
FOC09_RS08905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC09_RS08910	COG1126	abc transporter atp-binding protein
FOC09_RS08915	COG1115	amino acid carrier protein
FOC09_RS08920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC09_RS08930	COG0697	spore germination
FOC09_RS08945	COG0366	Alpha amylase catalytic
FOC09_RS08950	COG1263	PTS System
FOC09_RS08950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC09_RS08955	COG2188	Transcriptional regulator
FOC09_RS08960	COG0531	amino acid
FOC09_RS08980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC09_RS08985	COG0714	Associated with various cellular activities
FOC09_RS08990	COG4548	von Willebrand factor, type A
FOC09_RS09000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC09_RS09005	COG0156	8-amino-7-oxononanoate synthase activity
FOC09_RS09010	COG2226	methyltransferase
FOC09_RS09020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS09025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS09030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS09035	COG3104	oligopeptide transport
FOC09_RS09050	COG1620	l-lactate permease
FOC09_RS09055	COG1027	Aspartate ammonia-lyase
FOC09_RS09060	COG1253	flavin adenine dinucleotide binding
FOC09_RS09065	COG0346	lactoylglutathione lyase activity
FOC09_RS09070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS09075	COG1316	TRANSCRIPTIONal
FOC09_RS09080	COG2720	vancomycin resistance protein
FOC09_RS09100	COG3227	Zinc metalloprotease (Elastase)
FOC09_RS09115	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC09_RS09120	COG2217	Heavy metal translocating P-type atpase
FOC09_RS09125	COG0640	Transcriptional regulator
FOC09_RS09130	COG0531	amino acid
FOC09_RS09145	COG2427	Protein of unknown function (DUF1641)
FOC09_RS09150	COG3383	formate dehydrogenase (NAD+) activity
FOC09_RS09155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC09_RS09160	COG0456	acetyltransferase
FOC09_RS09160	COG0454	-acetyltransferase
FOC09_RS09165	COG0745	RESPONSE REGULATOR receiver
FOC09_RS09170	COG5002	protein histidine kinase activity
FOC09_RS09180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS09195	COG0281	malic enzyme
FOC09_RS09200	COG3493	citrate carrier protein
FOC09_RS09205	COG4565	transcriptional regulatory protein
FOC09_RS09210	COG3290	protein histidine kinase activity
FOC09_RS09220	COG4990	cell redox homeostasis
FOC09_RS09230	COG5002	protein histidine kinase activity
FOC09_RS09235	COG0745	RESPONSE REGULATOR receiver
FOC09_RS09240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC09_RS09250	COG0395	ABC-type sugar transport system, permease component
FOC09_RS09255	COG1175	transmembrane transport
FOC09_RS09260	COG3842	ATPase activity
FOC09_RS09265	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC09_RS09285	COG2851	Citrate transporter
FOC09_RS09295	COG3290	protein histidine kinase activity
FOC09_RS09305	COG2268	Band 7 protein
FOC09_RS09310	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC09_RS09320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC09_RS09325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS09340	COG2766	serine protein kinase
FOC09_RS09350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC09_RS09360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC09_RS09370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC09_RS09375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC09_RS09490	COG0735	belongs to the Fur family
FOC09_RS09495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC09_RS09515	COG4555	ABC transporter
FOC09_RS09525	COG0070	glutamate synthase
FOC09_RS09525	COG0069	glutamate synthase activity
FOC09_RS09525	COG0067	glutamate synthase
FOC09_RS09530	COG4129	membrane
FOC09_RS09535	COG1132	(ABC) transporter
FOC09_RS09560	COG1194	a g-specific adenine glycosylase
FOC09_RS09565	COG1988	membrane-bound metal-dependent
FOC09_RS09595	COG1090	epimerase
FOC09_RS09600	COG1228	amidohydrolase
FOC09_RS09620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC09_RS09640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC09_RS09640	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC09_RS09655	COG0463	Glycosyl transferase, family 2
FOC09_RS09670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC09_RS09675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC09_RS09675	COG1263	PTS System
FOC09_RS09680	COG2066	Belongs to the glutaminase family
FOC09_RS09700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC09_RS09705	COG0833	amino acid
FOC09_RS09715	COG3829	transcription factor binding
FOC09_RS09725	COG0101	tRNA pseudouridine synthase activity
FOC09_RS09930	COG1484	DNA-dependent DNA replication
FOC09_RS09965	COG1396	sequence-specific DNA binding
FOC09_RS09980	COG1396	sequence-specific DNA binding
FOC09_RS09985	COG0582	viral genome integration into host DNA
FOC09_RS09990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC09_RS09995	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC09_RS10020	COG0535	radical SAM domain protein
FOC09_RS10030	COG0387	Pfam Sodium calcium exchanger
FOC09_RS10035	COG3871	stress protein (general stress protein 26)
FOC09_RS10050	COG0586	Pfam SNARE associated Golgi protein
FOC09_RS10070	COG0697	spore germination
FOC09_RS10075	COG2217	Heavy metal translocating P-type atpase
FOC09_RS10080	COG1295	ribonuclease BN
FOC09_RS10090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC09_RS10105	COG3853	Toxic anion resistance protein (TelA)
FOC09_RS10115	COG0861	Integral membrane protein TerC family
FOC09_RS10120	COG2310	stress, protein
FOC09_RS10125	COG2310	stress, protein
FOC09_RS10130	COG2310	stress, protein
FOC09_RS10145	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC09_RS10160	COG2270	Major facilitator Superfamily
FOC09_RS10205	COG0488	(ABC) transporter
FOC09_RS10210	COG1116	anion transmembrane transporter activity
FOC09_RS10220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC09_RS10235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC09_RS10265	COG2190	(PTS) system
FOC09_RS10265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC09_RS10265	COG1263	PTS System
FOC09_RS10270	COG0366	Alpha amylase catalytic
FOC09_RS10275	COG0840	transmembrane signaling receptor activity
FOC09_RS10280	COG0840	transmembrane signaling receptor activity
FOC09_RS10290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC09_RS10295	COG0765	amino acid transport
FOC09_RS10305	COG0723	plastoquinol--plastocyanin reductase activity
FOC09_RS10305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC09_RS10310	COG2814	Major facilitator Superfamily
FOC09_RS10315	COG3541	Predicted nucleotidyltransferase
FOC09_RS10335	COG5002	protein histidine kinase activity
FOC09_RS10370	COG0166	Belongs to the GPI family
FOC09_RS10385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS10390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS10395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS10400	COG0235	Class ii aldolase
FOC09_RS10410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC09_RS10415	COG0450	alkyl hydroperoxide reductase
FOC09_RS10430	COG1473	amidohydrolase
FOC09_RS10460	COG4807	Protein conserved in bacteria
FOC09_RS10470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC09_RS10475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC09_RS10480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS10495	COG2309	aminopeptidase activity
FOC09_RS10500	COG2076	Multidrug Resistance protein
FOC09_RS10505	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS10515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC09_RS10520	COG0546	phosphoglycolate phosphatase activity
FOC09_RS10525	COG1597	lipid kinase activity
FOC09_RS10550	COG1846	Transcriptional regulator
FOC09_RS10570	COG1464	Belongs to the NlpA lipoprotein family
FOC09_RS10575	COG2011	ABC-type metal ion transport system permease component
FOC09_RS10580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC09_RS10585	COG1335	isochorismatase
FOC09_RS10600	COG4851	CamS sex pheromone cAM373 precursor
FOC09_RS10610	COG0210	DNA helicase
FOC09_RS10635	COG0151	Belongs to the GarS family
FOC09_RS10645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC09_RS10655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC09_RS10670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC09_RS10680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC09_RS10685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC09_RS10690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC09_RS10710	COG0745	RESPONSE REGULATOR receiver
FOC09_RS10715	COG2205	protein histidine kinase activity
FOC09_RS10730	COG1968	undecaprenyl-diphosphatase activity
FOC09_RS10770	COG2226	methyltransferase
FOC09_RS10805	COG5002	protein histidine kinase activity
FOC09_RS10815	COG2252	PERMEase
FOC09_RS10835	COG1266	CAAX protease self-immunity
FOC09_RS10850	COG0488	(ABC) transporter
FOC09_RS10855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC09_RS10860	COG0456	acetyltransferase
FOC09_RS10865	COG1214	PFAM Peptidase M22, glycoprotease
FOC09_RS10870	COG0802	atpase or kinase
FOC09_RS10965	COG2183	response to ionizing radiation
FOC09_RS10970	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC09_RS10975	COG0864	Transcriptional regulator
FOC09_RS10980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC09_RS10985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC09_RS10995	COG0457	Tetratricopeptide repeat
FOC09_RS10995	COG0705	Rhomboid family
FOC09_RS11000	COG4294	response to UV
FOC09_RS11010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC09_RS11020	COG2814	Major facilitator Superfamily
FOC09_RS11030	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC09_RS11035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC09_RS11055	COG4608	Belongs to the ABC transporter superfamily
FOC09_RS11060	COG0444	Belongs to the ABC transporter superfamily
FOC09_RS11070	COG0601	transmembrane transport
FOC09_RS11075	COG0747	negative chemotaxis
FOC09_RS11090	COG0488	(ABC) transporter
FOC09_RS11110	COG5298	Protein conserved in bacteria
FOC09_RS11115	COG0084	hydrolase, TatD family'
FOC09_RS11125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS11135	COG1609	Transcriptional regulator
FOC09_RS11145	COG0204	Acyl-transferase
FOC09_RS11160	COG0697	spore germination
FOC09_RS11165	COG0583	DNA-binding transcription factor activity
FOC09_RS11175	COG1910	domain protein
FOC09_RS11185	COG4149	molybdate abc transporter
FOC09_RS11190	COG4975	Glucose uptake
FOC09_RS11200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC09_RS11205	COG0656	L-ascorbic acid biosynthetic process
FOC09_RS11210	COG4166	transmembrane transport
FOC09_RS11215	COG4166	transmembrane transport
FOC09_RS11230	COG2207	Transcriptional regulator
FOC09_RS11240	COG4166	transmembrane transport
FOC09_RS11245	COG4608	Belongs to the ABC transporter superfamily
FOC09_RS11250	COG0444	Belongs to the ABC transporter superfamily
FOC09_RS11255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC09_RS11260	COG0601	transmembrane transport
FOC09_RS11275	COG2814	Major facilitator Superfamily
FOC09_RS11285	COG2271	Major facilitator Superfamily
FOC09_RS11290	COG0277	FAD linked oxidase domain protein
FOC09_RS11305	COG1464	Belongs to the NlpA lipoprotein family
FOC09_RS11310	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC09_RS11315	COG2011	ABC-type metal ion transport system permease component
FOC09_RS11350	COG4946	Tricorn protease homolog
FOC09_RS11350	COG1506	peptidase
FOC09_RS11350	COG0823	Involved in the tonB-independent uptake of proteins
FOC09_RS11355	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC09_RS11375	COG0596	Alpha beta hydrolase
FOC09_RS11380	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC09_RS11395	COG4856	YbbR-like protein
FOC09_RS11400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC09_RS11480	COG0726	polysaccharide deacetylase
FOC09_RS11485	COG2194	sulfuric ester hydrolase activity
FOC09_RS11495	COG0489	protein tyrosine kinase activity
FOC09_RS11500	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS11520	COG0101	tRNA pseudouridine synthase activity
FOC09_RS11525	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC09_RS11530	COG1122	ATPase activity
FOC09_RS11560	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC09_RS11570	COG0024	Methionine aminopeptidase
FOC09_RS11580	COG0201	protein transport
FOC09_RS11605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC09_RS11710	COG1358	cellular component organization or biogenesis
FOC09_RS11715	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC09_RS11725	COG2813	Specifically methylates the guanine in position
FOC09_RS11750	COG0250	Participates in transcription elongation, termination and antitermination
FOC09_RS11755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC09_RS11760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC09_RS11770	COG3688	RNA-binding protein containing a PIN domain
FOC09_RS11775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC09_RS11790	COG1045	serine acetyltransferase
FOC09_RS11810	COG4956	integral membrane protein (PIN domain superfamily)
FOC09_RS11820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC09_RS11825	COG0542	response to heat
FOC09_RS11835	COG3880	PFAM UvrB UvrC protein
FOC09_RS11865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC09_RS11870	COG1396	sequence-specific DNA binding
FOC09_RS11875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC09_RS11880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC09_RS11885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC09_RS11890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC09_RS11895	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC09_RS11900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC09_RS11905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC09_RS11920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC09_RS11930	COG0037	tRNA processing
FOC09_RS11935	COG2208	phosphoserine phosphatase activity
FOC09_RS11950	COG1098	S1 RNA binding domain
FOC09_RS11970	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC09_RS11975	COG3956	TIGRFAM MazG family protein
FOC09_RS11980	COG2244	polysaccharide biosynthetic process
FOC09_RS11985	COG2002	toxin-antitoxin pair type II binding
FOC09_RS11990	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC09_RS12000	COG0193	aminoacyl-tRNA hydrolase activity
FOC09_RS12005	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC09_RS12020	COG0251	oxidation-reduction process
FOC09_RS12025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC09_RS12040	COG4466	Protein conserved in bacteria
FOC09_RS12055	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC09_RS12060	COG0084	hydrolase, TatD family'
FOC09_RS12065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC09_RS12065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC09_RS12070	COG2002	toxin-antitoxin pair type II binding
FOC09_RS12075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC09_RS12085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC09_RS12095	COG1774	PSP1 C-terminal conserved region
FOC09_RS12100	COG0470	DNA polymerase III
FOC09_RS12110	COG1982	Orn Lys Arg decarboxylase major
FOC09_RS12165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC09_RS12175	COG0590	tRNA wobble adenosine to inosine editing
FOC09_RS12180	COG1335	isochorismatase
FOC09_RS12185	COG1428	Deoxynucleoside kinase
FOC09_RS12190	COG1428	Deoxynucleoside kinase
FOC09_RS12220	COG1686	Belongs to the peptidase S11 family
FOC09_RS12225	COG0517	IMP dehydrogenase activity
FOC09_RS12225	COG0516	GMP reductase activity
FOC09_RS12260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC09_RS12265	COG0187	DNA topoisomerase II activity
FOC09_RS12275	COG2501	S4 domain
FOC09_RS12280	COG0592	DNA-directed DNA polymerase activity
FOC09_RS12300	COG0706	membrane insertase activity
FOC09_RS12305	COG1847	R3H domain protein
FOC09_RS12310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC09_RS12330	COG1192	Involved in chromosome partitioning
FOC09_RS12335	COG1475	DNA binding
FOC09_RS12345	COG0668	transmembrane transport
FOC09_RS12350	COG4481	Protein conserved in bacteria
FOC09_RS12355	COG0012	GTP binding
FOC09_RS12365	COG0629	single-stranded DNA binding
FOC09_RS12375	COG4241	membrane
FOC09_RS12380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC09_RS12390	COG0305	Participates in initiation and elongation during chromosome replication
FOC09_RS12420	COG0745	RESPONSE REGULATOR receiver
FOC09_RS12425	COG5002	protein histidine kinase activity
FOC09_RS12430	COG4863	YycH protein
FOC09_RS12435	COG4853	Protein conserved in bacteria
FOC09_RS12440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC09_RS12445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC09_RS12465	COG1164	Oligoendopeptidase f
FOC09_RS12470	COG0516	GMP reductase activity
FOC09_RS12490	COG1272	protein, Hemolysin III
FOC09_RS12495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC09_RS12515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC09_RS12520	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC09_RS12525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC09_RS12530	COG2814	Major facilitator Superfamily
FOC09_RS12535	COG3275	phosphorelay sensor kinase activity
FOC09_RS12540	COG3279	Response regulator of the LytR AlgR family
FOC09_RS12555	COG0628	permease
FOC09_RS12560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC09_RS12560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC09_RS12565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC09_RS12570	COG1309	transcriptional regulator
FOC09_RS12575	COG0463	Glycosyl transferase, family 2
FOC09_RS12595	COG0488	(ABC) transporter
FOC09_RS12610	COG1607	acyl-coa hydrolase
FOC09_RS12620	COG0840	transmembrane signaling receptor activity
FOC09_RS12645	COG0477	Major facilitator Superfamily
FOC09_RS12650	COG3279	Response regulator of the LytR AlgR family
FOC09_RS12655	COG1966	Carbon starvation protein
FOC09_RS12660	COG2879	small protein
FOC09_RS12665	COG3706	GGDEF domain
FOC09_RS12670	COG0351	phosphomethylpyrimidine kinase
FOC09_RS12680	COG2197	response regulator
FOC09_RS12690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC09_RS12695	COG1011	Hydrolase
FOC09_RS12715	COG0460	homoserine dehydrogenase
FOC09_RS12725	COG1609	Transcriptional regulator
FOC09_RS12730	COG2755	lipolytic protein G-D-S-L family
FOC09_RS12735	COG1131	(ABC) transporter
FOC09_RS12740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC09_RS12750	COG2814	Major facilitator Superfamily
FOC09_RS12755	COG0561	phosphatase activity
FOC09_RS12760	COG2233	PERMEase
FOC09_RS12775	COG2363	Small membrane protein
FOC09_RS12785	COG3773	Cell wall hydrolase
FOC09_RS12800	COG0280	phosphate acetyltransferase
FOC09_RS12805	COG0095	Lipoate-protein ligase
FOC09_RS12830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS12835	COG1120	ATPase activity
FOC09_RS12840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS12845	COG1078	dGTPase activity
FOC09_RS12855	COG1994	Peptidase M50
FOC09_RS12865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC09_RS12870	COG0584	glycerophosphoryl diester phosphodiesterase
FOC09_RS12875	COG0789	Transcriptional regulator
FOC09_RS12880	COG2814	Major facilitator Superfamily
FOC09_RS12885	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC09_RS12890	COG0010	Belongs to the arginase family
FOC09_RS12905	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC09_RS12910	COG4506	Protein conserved in bacteria
FOC09_RS12915	COG0018	arginyl-trna synthetase
FOC09_RS12920	COG1595	DNA-templated transcription, initiation
FOC09_RS12940	COG2234	aminopeptidase activity
FOC09_RS12950	COG0024	Methionine aminopeptidase
FOC09_RS12955	COG1131	(ABC) transporter
FOC09_RS12960	COG0842	Transport permease protein
FOC09_RS12965	COG4585	Histidine kinase
FOC09_RS12970	COG2197	response regulator
FOC09_RS12995	COG5001	Diguanylate cyclase
FOC09_RS12995	COG3300	MHYT domain
FOC09_RS13005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC09_RS13010	COG0247	lactate metabolic process
FOC09_RS13010	COG2181	nitrate reductase activity
FOC09_RS13015	COG0183	Belongs to the thiolase family
FOC09_RS13020	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC09_RS13025	COG1960	acyl-CoA dehydrogenase activity
FOC09_RS13030	COG1960	acyl-CoA dehydrogenase activity
FOC09_RS13040	COG3343	RNA polymerase activity
FOC09_RS13050	COG4821	SIS domain
FOC09_RS13065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC09_RS13070	COG1494	fructose-1,6-bisphosphatase
FOC09_RS13075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC09_RS13090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC09_RS13095	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC09_RS13110	COG0009	L-threonylcarbamoyladenylate synthase
FOC09_RS13125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC09_RS13130	COG2259	Doxx family
FOC09_RS13135	COG2190	(PTS) system
FOC09_RS13145	COG0698	ribose 5-phosphate isomerase
FOC09_RS13180	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC09_RS13230	COG3300	MHYT domain
FOC09_RS13230	COG5001	Diguanylate cyclase
FOC09_RS13235	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC09_RS13245	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC09_RS13250	COG0649	NAD binding
FOC09_RS13265	COG0839	Belongs to the complex I subunit 6 family
FOC09_RS13275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC09_RS13280	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC09_RS13285	COG1007	ATP synthesis coupled electron transport
FOC09_RS13290	COG4836	Membrane
FOC09_RS13300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC09_RS13305	COG2385	sporulation resulting in formation of a cellular spore
FOC09_RS13310	COG4555	ABC transporter
FOC09_RS13315	COG3279	Response regulator of the LytR AlgR family
FOC09_RS13330	COG0739	heme binding
FOC09_RS13345	COG1609	Transcriptional regulator
FOC09_RS13390	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC09_RS13395	COG1682	transport, permease protein
FOC09_RS13400	COG1134	teichoic acid transport
FOC09_RS13405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC09_RS13420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC09_RS13425	COG0745	RESPONSE REGULATOR receiver
FOC09_RS13430	COG5002	protein histidine kinase activity
FOC09_RS13465	COG1136	(ABC) transporter
FOC09_RS13470	COG0577	efflux transmembrane transporter activity
FOC09_RS13480	COG1191	sigma factor activity
FOC09_RS13510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC09_RS13515	COG4715	Zinc finger, swim domain protein
FOC09_RS13540	COG3584	3D domain protein
FOC09_RS13540	COG1388	LysM domain
FOC09_RS13545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC09_RS13560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS13575	COG1368	sulfuric ester hydrolase activity
FOC09_RS13585	COG2389	metal-binding protein
FOC09_RS13595	COG1620	l-lactate permease
FOC09_RS13605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC09_RS13610	COG1294	oxidase, subunit
FOC09_RS13615	COG1271	oxidase subunit
FOC09_RS13630	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC09_RS13635	COG0583	DNA-binding transcription factor activity
FOC09_RS13640	COG1511	domain protein
FOC09_RS13645	COG0346	lactoylglutathione lyase activity
FOC09_RS13655	COG1301	dicarboxylic acid transport
FOC09_RS13660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC09_RS13670	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC09_RS13675	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC09_RS13680	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC09_RS13690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC09_RS13695	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC09_RS13700	COG1486	melibiose metabolic process
FOC09_RS13705	COG3394	polysaccharide catabolic process
FOC09_RS13720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC09_RS13720	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC09_RS13730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC09_RS13735	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC09_RS13740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC09_RS13745	COG1316	TRANSCRIPTIONal
FOC09_RS13750	COG1739	Uncharacterized protein family UPF0029
FOC09_RS13755	COG1307	EDD domain protein, DegV family
FOC09_RS13760	COG1733	regulation of RNA biosynthetic process
FOC09_RS13765	COG1388	LysM domain
FOC09_RS13765	COG0791	NLP P60 protein
FOC09_RS13770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC09_RS13775	COG1040	competence protein
FOC09_RS13780	COG1278	Cold shock
FOC09_RS13785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC09_RS13790	COG0653	protein targeting
FOC09_RS13810	COG2884	Cell division ATP-binding protein ftsE
FOC09_RS13815	COG2177	Part of the ABC transporter FtsEX involved in
FOC09_RS13820	COG3409	Peptidoglycan-binding domain 1 protein
FOC09_RS13820	COG0793	Belongs to the peptidase S41A family
FOC09_RS13825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC09_RS13830	COG1132	(ABC) transporter
FOC09_RS13845	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC09_RS13855	COG0583	DNA-binding transcription factor activity
FOC09_RS13860	COG2855	membrane
FOC09_RS13885	COG0789	Transcriptional regulator
FOC09_RS13905	COG0556	nucleotide-excision repair
FOC09_RS13910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC09_RS13920	COG1950	PFAM Membrane protein of
FOC09_RS13940	COG0110	maltose O-acetyltransferase activity
FOC09_RS13945	COG0457	Tetratricopeptide repeat
FOC09_RS13950	COG0492	ferredoxin-NADP+ reductase activity
FOC09_RS13960	COG1051	belongs to the nudix hydrolase family
FOC09_RS13970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC09_RS13980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC09_RS13985	COG0740	serine-type endopeptidase activity
FOC09_RS13990	COG2323	membrane
FOC09_RS14005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC09_RS14030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC09_RS14045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC09_RS14055	COG0149	triose-phosphate isomerase activity
FOC09_RS14060	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC09_RS14070	COG4974	Belongs to the 'phage' integrase family
FOC09_RS14095	COG4695	Portal protein
FOC09_RS14190	COG1346	cytolysis
FOC09_RS14195	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC09_RS14200	COG1647	Serine aminopeptidase, S33
FOC09_RS14205	COG0557	exoribonuclease II activity
FOC09_RS14255	COG3223	Belongs to the PsiE family
FOC09_RS14260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS14275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC09_RS14280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC09_RS14290	COG3290	protein histidine kinase activity
FOC09_RS14290	COG0840	transmembrane signaling receptor activity
FOC09_RS14300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC09_RS14305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC09_RS14310	COG1252	NADH dehydrogenase
FOC09_RS14320	COG1733	regulation of RNA biosynthetic process
FOC09_RS14325	COG2814	Major facilitator Superfamily
FOC09_RS14330	COG0656	L-ascorbic acid biosynthetic process
FOC09_RS14345	COG2910	NAD(P)H-binding
FOC09_RS14350	COG1115	amino acid carrier protein
FOC09_RS14355	COG1115	amino acid carrier protein
FOC09_RS14360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS14365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS14385	COG1611	Belongs to the LOG family
FOC09_RS14400	COG0783	Belongs to the Dps family
FOC09_RS14405	COG1115	amino acid carrier protein
FOC09_RS14410	COG0490	domain, Protein
FOC09_RS14415	COG0475	glutathione-regulated potassium exporter activity
FOC09_RS14430	COG1741	Belongs to the pirin family
FOC09_RS14435	COG3227	Zinc metalloprotease (Elastase)
FOC09_RS14440	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC09_RS14455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC09_RS14465	COG5002	protein histidine kinase activity
FOC09_RS14470	COG0745	RESPONSE REGULATOR receiver
FOC09_RS14475	COG1376	ErfK ybiS ycfS ynhG family protein
FOC09_RS14485	COG0586	Pfam SNARE associated Golgi protein
FOC09_RS14520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS14530	COG0706	membrane insertase activity
FOC09_RS14540	COG0531	amino acid
FOC09_RS14545	COG2814	Major facilitator Superfamily
FOC09_RS14560	COG0840	transmembrane signaling receptor activity
FOC09_RS14565	COG0011	TIGRFAM Protein of
FOC09_RS14580	COG1686	Belongs to the peptidase S11 family
FOC09_RS14590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC09_RS14590	COG1024	Enoyl-CoA hydratase
FOC09_RS14595	COG0183	Belongs to the thiolase family
FOC09_RS14600	COG1960	acyl-CoA dehydrogenase activity
FOC09_RS14605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS14610	COG1309	transcriptional regulator
FOC09_RS14630	COG0039	L-malate dehydrogenase activity
FOC09_RS14675	COG1393	Belongs to the ArsC family
FOC09_RS14690	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC09_RS14695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC09_RS14705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC09_RS14710	COG2011	ABC-type metal ion transport system permease component
FOC09_RS14715	COG1464	Belongs to the NlpA lipoprotein family
FOC09_RS14720	COG1464	Belongs to the NlpA lipoprotein family
FOC09_RS14725	COG0396	ATPase activity
FOC09_RS14730	COG0719	Fe-S assembly protein
FOC09_RS14735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC09_RS14740	COG0822	iron-sulfur transferase activity
FOC09_RS14745	COG0719	Fe-S assembly protein
FOC09_RS14755	COG1695	Transcriptional regulator
FOC09_RS14760	COG0737	Belongs to the 5'-nucleotidase family
FOC09_RS14765	COG3377	Domain of unknown function (DUF1805)
FOC09_RS14775	COG0739	heme binding
FOC09_RS14800	COG4377	Putative membrane peptidase family (DUF2324)
FOC09_RS14805	COG0789	Transcriptional regulator
FOC09_RS14815	COG4470	Protein conserved in bacteria
FOC09_RS14830	COG1494	fructose-1,6-bisphosphatase
FOC09_RS14835	COG2445	Protein of unknown function DUF86
FOC09_RS14845	COG0647	UMP catabolic process
FOC09_RS14850	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC09_RS14860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC09_RS14865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC09_RS14875	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC09_RS14880	COG4837	Protein of unknown function (DUF1462)
FOC09_RS14920	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC09_RS14925	COG0390	transport system, permease component
FOC09_RS14940	COG1252	NADH dehydrogenase
FOC09_RS14955	COG0316	Belongs to the HesB IscA family
FOC09_RS14975	COG1683	Conserved Protein
FOC09_RS14990	COG3708	Transcriptional regulator
FOC09_RS15005	COG1252	NADH dehydrogenase
FOC09_RS15020	COG3584	3D domain protein
FOC09_RS15035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC09_RS15040	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC09_RS15050	COG1268	BioY protein
FOC09_RS15060	COG2050	protein possibly involved in aromatic compounds catabolism
FOC09_RS15065	COG0423	glycine-tRNA ligase activity
FOC09_RS15080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC09_RS15085	COG5018	Exonuclease
FOC09_RS15100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC09_RS15110	COG2267	carboxylic ester hydrolase activity
FOC09_RS15115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC09_RS15120	COG1522	sequence-specific DNA binding
FOC09_RS15125	COG0436	Aminotransferase
FOC09_RS15130	COG1098	S1 RNA binding domain
FOC09_RS15135	COG2155	Conserved Protein
FOC09_RS15140	COG0166	Belongs to the GPI family
FOC09_RS15150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC09_RS15155	COG1285	pathogenesis
FOC09_RS15190	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC09_RS15285	COG0039	L-malate dehydrogenase activity
FOC09_RS15305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC09_RS15310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC09_RS15315	COG0297	glycogen (starch) synthase activity
FOC09_RS15320	COG0058	SHG alpha-glucan phosphorylase activity
FOC09_RS15335	COG1278	Cold shock
FOC09_RS15340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC09_RS15345	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC09_RS15350	COG1169	isochorismate synthase
FOC09_RS15355	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC09_RS15360	COG0596	Alpha beta hydrolase
FOC09_RS15365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC09_RS15375	COG4948	Mandelate Racemase Muconate Lactonizing
FOC09_RS15405	COG3964	amidohydrolase
FOC09_RS15445	COG1136	(ABC) transporter
FOC09_RS15450	COG0577	efflux transmembrane transporter activity
FOC09_RS15460	COG2205	protein histidine kinase activity
FOC09_RS15465	COG0745	RESPONSE REGULATOR receiver
FOC09_RS15470	COG3708	Transcriptional regulator
FOC09_RS15470	COG2207	Transcriptional regulator
FOC09_RS15475	COG1136	(ABC) transporter
FOC09_RS15480	COG0577	efflux transmembrane transporter activity
FOC09_RS15490	COG0586	Pfam SNARE associated Golgi protein
FOC09_RS15525	COG1597	lipid kinase activity
FOC09_RS15555	COG0745	RESPONSE REGULATOR receiver
FOC09_RS15560	COG5002	protein histidine kinase activity
FOC09_RS15595	COG1842	Phage shock protein A
FOC09_RS15620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS15640	COG1294	oxidase, subunit
FOC09_RS15645	COG1271	oxidase subunit
FOC09_RS15650	COG0288	reversible hydration of carbon dioxide
FOC09_RS15680	COG0494	nUDIX hydrolase
FOC09_RS15705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC09_RS15710	COG1116	anion transmembrane transporter activity
FOC09_RS15715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC09_RS15735	COG2267	carboxylic ester hydrolase activity
FOC09_RS15740	COG4191	Histidine kinase
FOC09_RS15745	COG5002	protein histidine kinase activity
FOC09_RS15750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC09_RS15800	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC09_RS15810	COG0438	transferase activity, transferring glycosyl groups
FOC09_RS15815	COG0671	phosphoesterase, PA-phosphatase related
FOC09_RS15820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC09_RS15825	COG2267	carboxylic ester hydrolase activity
FOC09_RS15845	COG1794	racemase activity, acting on amino acids and derivatives
FOC09_RS15855	COG1131	(ABC) transporter
FOC09_RS15860	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC09_RS15865	COG1242	4 iron, 4 sulfur cluster binding
FOC09_RS15885	COG1136	(ABC) transporter
FOC09_RS15895	COG0582	viral genome integration into host DNA
FOC09_RS15900	COG0490	domain, Protein
FOC09_RS15905	COG0475	glutathione-regulated potassium exporter activity
FOC09_RS15910	COG2814	Major facilitator Superfamily
FOC09_RS15950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC09_RS15960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC09_RS15985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC09_RS15995	COG0303	'Molybdopterin
FOC09_RS16000	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC09_RS16005	COG0314	molybdopterin synthase activity
FOC09_RS16020	COG4975	Glucose uptake
FOC09_RS16030	COG1329	Transcriptional regulator
FOC09_RS16050	COG3832	glyoxalase III activity
FOC09_RS16060	COG2814	Major facilitator Superfamily
FOC09_RS16065	COG2081	HI0933 family
FOC09_RS16070	COG2244	polysaccharide biosynthetic process
FOC09_RS16075	COG1187	pseudouridine synthase activity
FOC09_RS16080	COG1349	DNA-binding transcription factor activity
FOC09_RS16095	COG1523	belongs to the glycosyl hydrolase 13 family
FOC09_RS16100	COG0510	thiamine kinase activity
FOC09_RS16115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS16125	COG1363	Peptidase, m42
FOC09_RS16130	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC09_RS16135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC09_RS16140	COG4848	Belongs to the UPF0354 family
FOC09_RS16145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC09_RS16155	COG1674	ftsk spoiiie
FOC09_RS16170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS16190	COG2309	aminopeptidase activity
FOC09_RS16200	COG3118	belongs to the thioredoxin family
FOC09_RS16205	COG4851	CamS sex pheromone cAM373 precursor
FOC09_RS16210	COG1609	Transcriptional regulator
FOC09_RS16245	COG0666	response to abiotic stimulus
FOC09_RS16255	COG0745	RESPONSE REGULATOR receiver
FOC09_RS16265	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC09_RS16270	COG0517	IMP dehydrogenase activity
FOC09_RS16275	COG0454	-acetyltransferase
FOC09_RS16280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC09_RS16295	COG1595	DNA-templated transcription, initiation
FOC09_RS16305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC09_RS16325	COG0626	cystathionine gamma-synthase activity
FOC09_RS16330	COG1956	GAF domain-containing protein
FOC09_RS16340	COG0697	spore germination
FOC09_RS16345	COG0583	DNA-binding transcription factor activity
FOC09_RS16355	COG1104	cysteine desulfurase activity
FOC09_RS16370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC09_RS16380	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC09_RS16385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC09_RS16395	COG3874	Sporulation protein YtfJ
FOC09_RS16400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC09_RS16405	COG0827	DNA restriction-modification system
FOC09_RS16410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC09_RS16430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS16470	COG0589	response to stress
FOC09_RS16475	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS16490	COG1476	TRANSCRIPTIONal
FOC09_RS16500	COG0662	Cupin 2, conserved barrel domain protein
FOC09_RS16505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS16540	COG0006	proline dipeptidase activity
FOC09_RS16555	COG4109	DRTGG domain
FOC09_RS16575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC09_RS16590	COG0587	DNA-directed DNA polymerase activity
FOC09_RS16595	COG0281	malic enzyme
FOC09_RS16600	COG1725	Transcriptional regulator
FOC09_RS16625	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC09_RS16630	COG0628	permease
FOC09_RS16640	COG0372	Belongs to the citrate synthase family
FOC09_RS16645	COG0538	isocitrate dehydrogenase activity
FOC09_RS16660	COG0745	RESPONSE REGULATOR receiver
FOC09_RS16665	COG5002	protein histidine kinase activity
FOC09_RS16670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC09_RS16670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC09_RS16675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC09_RS16680	COG1971	Probably functions as a manganese efflux pump
FOC09_RS16685	COG0237	dephospho-CoA kinase activity
FOC09_RS16690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC09_RS16700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC09_RS16710	COG3611	Membrane attachment protein
FOC09_RS16715	COG1484	DNA-dependent DNA replication
FOC09_RS16725	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC09_RS16730	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC09_RS16750	COG1363	Peptidase, m42
FOC09_RS16755	COG1309	transcriptional regulator
FOC09_RS16760	COG1566	PFAM secretion protein HlyD family protein
FOC09_RS16765	COG2814	Major facilitator Superfamily
FOC09_RS16790	COG1418	mRNA catabolic process
FOC09_RS16800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC09_RS16810	COG0072	phenylalanine-tRNA ligase activity
FOC09_RS16810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC09_RS16815	COG0017	Asparaginyl-tRNA synthetase
FOC09_RS16845	COG1286	toxin biosynthetic process
FOC09_RS16850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC09_RS16850	COG1796	DNA polymerase
FOC09_RS16860	COG1187	pseudouridine synthase activity
FOC09_RS16865	COG1114	Component of the transport system for branched-chain amino acids
FOC09_RS16870	COG5386	Cell surface protein
FOC09_RS16880	COG5386	Cell surface protein
FOC09_RS16895	COG1120	ATPase activity
FOC09_RS16900	COG4509	Sortase family
FOC09_RS16915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC09_RS16920	COG4895	conserved protein (DUF2196)
FOC09_RS16925	COG0745	RESPONSE REGULATOR receiver
FOC09_RS16930	COG2205	protein histidine kinase activity
FOC09_RS16935	COG1131	(ABC) transporter
FOC09_RS16960	COG2318	DinB family
FOC09_RS16980	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS16985	COG1309	transcriptional regulator
FOC09_RS16990	COG1024	Enoyl-CoA hydratase
FOC09_RS16995	COG2086	electron transfer activity
FOC09_RS17000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC09_RS17005	COG3118	belongs to the thioredoxin family
FOC09_RS17015	COG1719	4-vinyl reductase, 4VR
FOC09_RS17020	COG2009	succinate dehydrogenase
FOC09_RS17025	COG1053	succinate dehydrogenase
FOC09_RS17030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC09_RS17035	COG0824	Thioesterase
FOC09_RS17040	COG1876	peptidase activity
FOC09_RS17045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC09_RS17055	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC09_RS17060	COG4152	abc transporter atp-binding protein
FOC09_RS17065	COG1668	transmembrane transport
FOC09_RS17070	COG1959	2 iron, 2 sulfur cluster binding
FOC09_RS17080	COG0697	spore germination
FOC09_RS17085	COG1396	sequence-specific DNA binding
FOC09_RS17090	COG1983	PspC domain protein
FOC09_RS17105	COG3279	Response regulator of the LytR AlgR family
FOC09_RS17115	COG4608	Belongs to the ABC transporter superfamily
FOC09_RS17120	COG0444	Belongs to the ABC transporter superfamily
FOC09_RS17140	COG0402	S-adenosylhomocysteine deaminase activity
FOC09_RS17145	COG0402	S-adenosylhomocysteine deaminase activity
FOC09_RS17155	COG2233	PERMEase
FOC09_RS17160	COG2197	response regulator
FOC09_RS17175	COG1309	transcriptional regulator
FOC09_RS17195	COG5401	PFAM Sporulation and spore germination
FOC09_RS17205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC09_RS17210	COG0622	Phosphoesterase
FOC09_RS17255	COG0470	DNA polymerase III
FOC09_RS17255	COG1067	ATP-dependent peptidase activity
FOC09_RS17270	COG1764	response to oxidative stress
FOC09_RS17275	COG1846	Transcriptional regulator
FOC09_RS17285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC09_RS17295	COG1587	Uroporphyrinogen-III synthase
FOC09_RS17300	COG0113	porphobilinogen synthase activity
FOC09_RS17310	COG1388	LysM domain
FOC09_RS17320	COG0525	valine-tRNA ligase activity
FOC09_RS17325	COG0285	dihydrofolate synthase activity
FOC09_RS17345	COG1077	Cell shape determining protein MreB Mrl
FOC09_RS17350	COG1792	Involved in formation and maintenance of cell shape
FOC09_RS17365	COG2894	cell division
FOC09_RS17370	COG0739	heme binding
FOC09_RS17375	COG1994	Peptidase M50
FOC09_RS17380	COG1530	ribonuclease E activity
FOC09_RS17390	COG2868	ribosomal protein
FOC09_RS17400	COG3290	protein histidine kinase activity
FOC09_RS17405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC09_RS17410	COG0745	RESPONSE REGULATOR receiver
FOC09_RS17420	COG1136	(ABC) transporter
FOC09_RS17425	COG0577	efflux transmembrane transporter activity
FOC09_RS17430	COG0577	efflux transmembrane transporter activity
FOC09_RS17435	COG0077	Prephenate dehydratase
FOC09_RS17440	COG2258	MOSC domain
FOC09_RS17445	COG1827	regulation of RNA biosynthetic process
FOC09_RS17450	COG1104	cysteine desulfurase activity
FOC09_RS17455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC09_RS17460	COG0157	Belongs to the NadC ModD family
FOC09_RS17485	COG0640	Transcriptional regulator
FOC09_RS17490	COG0697	spore germination
FOC09_RS17495	COG0697	spore germination
FOC09_RS17505	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC09_RS17535	COG1862	Preprotein translocase
FOC09_RS17545	COG2323	membrane
FOC09_RS17550	COG2244	polysaccharide biosynthetic process
FOC09_RS17560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC09_RS17560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC09_RS17565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC09_RS17570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC09_RS17570	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC09_RS17580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC09_RS17590	COG0124	histidyl-tRNA synthetase
FOC09_RS17600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC09_RS17610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC09_RS17615	COG1959	2 iron, 2 sulfur cluster binding
FOC09_RS17620	COG1104	cysteine desulfurase activity
FOC09_RS17625	COG0482	sulfurtransferase activity
FOC09_RS17635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC09_RS17655	COG0628	permease
FOC09_RS17665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC09_RS17685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC09_RS17715	COG0768	penicillin binding
FOC09_RS17740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC09_RS17745	COG0626	cystathionine gamma-synthase activity
FOC09_RS17750	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS17750	COG1454	alcohol dehydrogenase
FOC09_RS17760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS17800	COG2259	Doxx family
FOC09_RS17815	COG3186	Phenylalanine-4-hydroxylase
FOC09_RS17820	COG1404	Belongs to the peptidase S8 family
FOC09_RS17855	COG2267	carboxylic ester hydrolase activity
FOC09_RS17865	COG1785	Belongs to the alkaline phosphatase family
FOC09_RS17875	COG2357	RelA SpoT domain protein
FOC09_RS17880	COG0778	Nitroreductase
FOC09_RS17890	COG1595	DNA-templated transcription, initiation
FOC09_RS17900	COG1191	sigma factor activity
FOC09_RS17915	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC09_RS17920	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC09_RS17930	COG1534	Rna-binding protein
FOC09_RS17940	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC09_RS17945	COG0799	negative regulation of ribosome biogenesis
FOC09_RS17950	COG2226	methyltransferase
FOC09_RS17955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC09_RS17960	COG1596	polysaccharide export
FOC09_RS17960	COG1555	photosystem II stabilization
FOC09_RS17965	COG2131	deaminase
FOC09_RS17970	COG0658	competence protein
FOC09_RS17970	COG2333	competence protein COMEC
FOC09_RS17980	COG1466	dna polymerase III delta subunit
FOC09_RS18005	COG1733	regulation of RNA biosynthetic process
FOC09_RS18010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC09_RS18020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC09_RS18040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC09_RS18045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC09_RS18055	COG1610	YqeY-like protein
FOC09_RS18070	COG1702	phosphate starvation-inducible protein PhoH
FOC09_RS18075	COG1480	7TM receptor with intracellular HD hydrolase
FOC09_RS18085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC09_RS18090	COG0295	cytidine deaminase activity
FOC09_RS18095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC09_RS18110	COG0517	IMP dehydrogenase activity
FOC09_RS18120	COG0358	DNA primase activity
FOC09_RS18125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC09_RS18130	COG2010	Cytochrome c
FOC09_RS18135	COG2384	SAM-dependent methyltransferase
FOC09_RS18140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC09_RS18170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS18175	COG1121	(ABC) transporter
FOC09_RS18180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC09_RS18185	COG0735	belongs to the Fur family
FOC09_RS18210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC09_RS18215	COG0477	Major facilitator Superfamily
FOC09_RS18225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC09_RS18230	COG0573	inorganic phosphate transmembrane transporter activity
FOC09_RS18235	COG0581	inorganic phosphate transmembrane transporter activity
FOC09_RS18240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC09_RS18245	COG0704	Plays a role in the regulation of phosphate uptake
FOC09_RS18250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC09_RS18260	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC09_RS18265	COG4483	Protein conserved in bacteria
FOC09_RS18270	COG1940	carbohydrate kinase activity
FOC09_RS18280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS18300	COG0626	cystathionine gamma-synthase activity
FOC09_RS18305	COG0626	cystathionine gamma-synthase activity
FOC09_RS18310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC09_RS18310	COG0646	methionine synthase
FOC09_RS18315	COG0646	methionine synthase
FOC09_RS18315	COG1410	methionine synthase
FOC09_RS18320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC09_RS18370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC09_RS18375	COG1459	type II secretion system
FOC09_RS18385	COG4970	Tfp pilus assembly protein FimT
FOC09_RS18440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC09_RS18470	COG1725	Transcriptional regulator
FOC09_RS18475	COG1131	(ABC) transporter
FOC09_RS18510	COG2076	Multidrug Resistance protein
FOC09_RS18515	COG2076	Multidrug Resistance protein
FOC09_RS18525	COG1609	Transcriptional regulator
FOC09_RS18530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC09_RS18535	COG0095	Lipoate-protein ligase
FOC09_RS18555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC09_RS18565	COG3872	metal-dependent enzyme
FOC09_RS18580	COG0006	proline dipeptidase activity
FOC09_RS18605	COG3854	ATPases associated with a variety of cellular activities
FOC09_RS18650	COG0511	ligase activity, forming carbon-carbon bonds
FOC09_RS18655	COG0439	Biotin carboxylase
FOC09_RS18660	COG1302	Protein conserved in bacteria
FOC09_RS18685	COG0142	geranyltranstransferase activity
FOC09_RS18695	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC09_RS18705	COG0497	DNA recombination
FOC09_RS18710	COG0750	zinc metalloprotease
FOC09_RS18715	COG0745	RESPONSE REGULATOR receiver
FOC09_RS18725	COG3093	addiction module antidote protein HigA
FOC09_RS18730	COG0584	glycerophosphoryl diester phosphodiesterase
FOC09_RS18740	COG3829	transcription factor binding
FOC09_RS18740	COG3290	protein histidine kinase activity
FOC09_RS18745	COG0280	phosphate acetyltransferase
FOC09_RS18750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC09_RS18760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC09_RS18765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC09_RS18770	COG0022	dehydrogenase e1 component
FOC09_RS18775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC09_RS18780	COG0772	Belongs to the SEDS family
FOC09_RS18800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC09_RS18805	COG0765	amino acid transport
FOC09_RS18810	COG1126	abc transporter atp-binding protein
FOC09_RS18815	COG4129	membrane
FOC09_RS18820	COG1376	ErfK ybiS ycfS ynhG family protein
FOC09_RS18835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS18840	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC09_RS18850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC09_RS18870	COG1760	l-serine dehydratase
FOC09_RS18875	COG1760	l-serine dehydratase
FOC09_RS18880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC09_RS18890	COG0300	oxidoreductase activity
FOC09_RS18905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC09_RS18915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC09_RS18935	COG1522	sequence-specific DNA binding
FOC09_RS18945	COG0737	Belongs to the 5'-nucleotidase family
FOC09_RS18960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC09_RS18970	COG0156	8-amino-7-oxononanoate synthase activity
FOC09_RS18975	COG1073	alpha beta
FOC09_RS18975	COG2226	methyltransferase
FOC09_RS18980	COG4106	trans-aconitate 2-methyltransferase activity
FOC09_RS18985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC09_RS19005	COG0307	riboflavin synthase, alpha
FOC09_RS19010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC09_RS19010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC09_RS19025	COG1073	alpha beta
FOC09_RS19030	COG0456	acetyltransferase
FOC09_RS19035	COG1609	Transcriptional regulator
FOC09_RS19040	COG2056	Na+-H+ antiporter family
FOC09_RS19045	COG0596	Alpha beta hydrolase
FOC09_RS19055	COG4085	toxin activity
FOC09_RS19055	COG1525	nuclease
FOC09_RS19055	COG0737	Belongs to the 5'-nucleotidase family
FOC09_RS19065	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC09_RS19065	COG0456	acetyltransferase
FOC09_RS19070	COG0656	L-ascorbic acid biosynthetic process
FOC09_RS19075	COG0667	Aldo Keto reductase
FOC09_RS19095	COG1300	Membrane
FOC09_RS19100	COG0735	belongs to the Fur family
FOC09_RS19110	COG4974	Belongs to the 'phage' integrase family
FOC09_RS19135	COG0598	Magnesium transport protein CorA
FOC09_RS19150	COG1846	Transcriptional regulator
FOC09_RS19165	COG1131	(ABC) transporter
FOC09_RS19170	COG1725	Transcriptional regulator
FOC09_RS19175	COG1686	Belongs to the peptidase S11 family
FOC09_RS19195	COG0733	neurotransmitter:sodium symporter activity
FOC09_RS19220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC09_RS19235	COG0697	spore germination
FOC09_RS19240	COG0561	phosphatase activity
FOC09_RS19245	COG4086	secreted protein
FOC09_RS19250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC09_RS19255	COG0456	acetyltransferase
FOC09_RS19260	COG1547	Domain of unknown function (DUF309)
FOC09_RS19285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC09_RS19305	COG3711	transcriptional antiterminator
FOC09_RS19310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC09_RS19310	COG1263	PTS System
FOC09_RS19310	COG2190	(PTS) system
FOC09_RS19335	COG0778	Nitroreductase
FOC09_RS19340	COG3706	GGDEF domain
FOC09_RS19360	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC09_RS19380	COG0436	Aminotransferase
FOC09_RS19385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC09_RS19405	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS19410	COG1695	Transcriptional regulator
FOC09_RS19450	COG0183	Belongs to the thiolase family
FOC09_RS19490	COG3842	ATPase activity
FOC09_RS19495	COG0366	Alpha amylase catalytic
FOC09_RS19505	COG2182	Extracellular solute-binding protein
FOC09_RS19510	COG1175	transmembrane transport
FOC09_RS19515	COG3833	ABC-type maltose transport systems, permease component
FOC09_RS19520	COG1609	Transcriptional regulator
FOC09_RS19525	COG0436	Aminotransferase
FOC09_RS19535	COG2205	protein histidine kinase activity
FOC09_RS19545	COG3209	COG3209 Rhs family protein
FOC09_RS19565	COG2814	Major facilitator Superfamily
FOC09_RS19600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC09_RS19610	COG1408	metallophosphoesterase
FOC09_RS19615	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS19620	COG2200	EAL domain
FOC09_RS19635	COG4703	Protein of unknown function (DUF1797)
FOC09_RS19640	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC09_RS19650	COG0517	IMP dehydrogenase activity
FOC09_RS19655	COG0583	DNA-binding transcription factor activity
FOC09_RS19675	COG0569	domain protein
FOC09_RS19680	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC09_RS19690	COG0561	phosphatase activity
FOC09_RS19695	COG0242	peptide deformylase activity
FOC09_RS19705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC09_RS19710	COG0022	dehydrogenase e1 component
FOC09_RS19715	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC09_RS19760	COG1982	Orn Lys Arg decarboxylase major
FOC09_RS19780	COG0483	inositol monophosphate 1-phosphatase activity
FOC09_RS19805	COG4896	Protein conserved in bacteria
FOC09_RS19815	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC09_RS19820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC09_RS19825	COG4838	Belongs to the UPF0358 family
FOC09_RS19830	COG0772	Belongs to the SEDS family
FOC09_RS19835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC09_RS19870	COG3336	cytochrome c oxidase
FOC09_RS19885	COG2340	Cysteine-rich secretory protein family
FOC09_RS19900	COG0406	alpha-ribazole phosphatase activity
FOC09_RS19905	COG3679	Belongs to the UPF0342 family
FOC09_RS19920	COG0742	ribosomal rna small subunit methyltransferase
FOC09_RS19930	COG3314	Sporulation integral membrane protein YlbJ
FOC09_RS19935	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC09_RS19940	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC09_RS19950	COG0582	viral genome integration into host DNA
FOC09_RS19960	COG1396	sequence-specific DNA binding
FOC09_RS19970	COG1396	sequence-specific DNA binding
FOC09_RS19990	COG1484	DNA-dependent DNA replication
FOC09_RS20015	COG1191	sigma factor activity
FOC09_RS20090	COG0582	viral genome integration into host DNA
FOC09_RS20115	COG4626	Terminase
FOC09_RS20115	COG1802	Transcriptional regulator
FOC09_RS20205	COG4824	toxin secretion phage lysis holin
FOC09_RS20255	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC09_RS20280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC09_RS20295	COG4839	cell division protein FtsL
FOC09_RS20305	COG0768	penicillin binding
FOC09_RS20310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC09_RS20325	COG0772	Belongs to the SEDS family
FOC09_RS20330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC09_RS20335	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC09_RS20340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC09_RS20345	COG0849	cell division
FOC09_RS20350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC09_RS20360	COG1191	sigma factor activity
FOC09_RS20365	COG1191	sigma factor activity
FOC09_RS20370	COG1873	PFAM PRC-barrel domain
FOC09_RS20380	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC09_RS20390	COG0762	integral membrane protein
FOC09_RS20395	COG2302	S4 RNA-binding domain
FOC09_RS20400	COG3599	regulation of cell shape
FOC09_RS20405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC09_RS20420	COG0564	pseudouridine synthase activity
FOC09_RS20445	COG0505	Belongs to the CarA family
FOC09_RS20485	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC09_RS20500	COG0006	proline dipeptidase activity
FOC09_RS20510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC09_RS20515	COG1561	YicC-like family, N-terminal region
FOC09_RS20525	COG0194	GDP metabolic process
FOC09_RS20535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC09_RS20540	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC09_RS20545	COG0242	peptide deformylase activity
FOC09_RS20555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC09_RS20555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC09_RS20565	COG0631	protein serine/threonine phosphatase activity
FOC09_RS20570	COG2815	serine threonine protein kinase
FOC09_RS20570	COG0515	serine threonine protein kinase
FOC09_RS20575	COG1162	GTPase activity
FOC09_RS20580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC09_RS20585	COG1564	THIamine pyrophosphokinase
FOC09_RS20600	COG1302	Protein conserved in bacteria
FOC09_RS20605	COG1461	Dihydroxyacetone kinase
FOC09_RS20610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC09_RS20625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC09_RS20630	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS20645	COG1196	nuclear chromosome segregation
FOC09_RS20650	COG0552	protein localization to endoplasmic reticulum
FOC09_RS20660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC09_RS20670	COG1837	Belongs to the UPF0109 family
FOC09_RS20710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC09_RS20720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC09_RS20730	COG4974	Belongs to the 'phage' integrase family
FOC09_RS20760	COG0528	UMP kinase activity
FOC09_RS20770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC09_RS20775	COG4589	Belongs to the CDS family
FOC09_RS20780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC09_RS20785	COG0750	zinc metalloprotease
FOC09_RS20805	COG0195	Participates in both transcription termination and antitermination
FOC09_RS20810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC09_RS20815	COG1358	cellular component organization or biogenesis
FOC09_RS20825	COG1550	Protein conserved in bacteria
FOC09_RS20835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC09_RS20840	COG0196	riboflavin kinase activity
FOC09_RS20855	COG0726	polysaccharide deacetylase
FOC09_RS20860	COG0612	Peptidase, M16
FOC09_RS20865	COG1873	PFAM PRC-barrel domain
FOC09_RS20870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC09_RS20875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC09_RS20880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC09_RS20885	COG0527	aspartate kinase activity
FOC09_RS20895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC09_RS20900	COG0740	serine-type endopeptidase activity
FOC09_RS20910	COG1674	ftsk spoiiie
FOC09_RS20915	COG2188	Transcriptional regulator
FOC09_RS20940	COG0612	Peptidase, M16
FOC09_RS20945	COG0612	Peptidase, M16
FOC09_RS20950	COG0300	oxidoreductase activity
FOC09_RS20965	COG1426	Protein conserved in bacteria
FOC09_RS20970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC09_RS20995	COG1692	metallophosphoesterase
FOC09_RS21000	COG2359	stage V sporulation protein S
FOC09_RS21010	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC09_RS21010	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC09_RS21015	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC09_RS21020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC09_RS21025	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC09_RS21070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC09_RS21080	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC09_RS21085	COG1368	sulfuric ester hydrolase activity
FOC09_RS21090	COG0562	UDP-galactopyranose mutase
FOC09_RS21095	COG3773	Cell wall hydrolase
FOC09_RS21100	COG1404	Belongs to the peptidase S8 family
FOC09_RS21120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC09_RS21125	COG0596	Alpha beta hydrolase
FOC09_RS21125	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC09_RS21130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS21135	COG1380	Effector of murein hydrolase LrgA
FOC09_RS21140	COG1346	cytolysis
FOC09_RS21160	COG3300	MHYT domain
FOC09_RS21160	COG5001	Diguanylate cyclase
FOC09_RS21165	COG0346	lactoylglutathione lyase activity
FOC09_RS21170	COG2267	carboxylic ester hydrolase activity
FOC09_RS21185	COG2364	Membrane
FOC09_RS21195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC09_RS21200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC09_RS21205	COG2169	Transcriptional regulator
FOC09_RS21210	COG0708	Exodeoxyribonuclease III
FOC09_RS21220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS21225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS21230	COG1120	ATPase activity
FOC09_RS21235	COG2819	hydrolase of the alpha beta superfamily
FOC09_RS21245	COG1937	Protein conserved in bacteria
FOC09_RS21250	COG2608	mercury ion transmembrane transporter activity
FOC09_RS21255	COG2217	Heavy metal translocating P-type atpase
FOC09_RS21265	COG2116	formate transmembrane transporter activity
FOC09_RS21270	COG1408	metallophosphoesterase
FOC09_RS21280	COG1113	amino acid transport
FOC09_RS21290	COG2322	membrane
FOC09_RS21300	COG1349	DNA-binding transcription factor activity
FOC09_RS21305	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC09_RS21310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC09_RS21310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC09_RS21310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC09_RS21315	COG3584	3D domain protein
FOC09_RS21315	COG1388	LysM domain
FOC09_RS21345	COG0464	growth
FOC09_RS21355	COG2860	membrane
FOC09_RS21365	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC09_RS21370	COG0789	Transcriptional regulator
FOC09_RS21375	COG0174	glutamine synthetase
FOC09_RS21395	COG1396	sequence-specific DNA binding
FOC09_RS21475	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC09_RS21510	COG1595	DNA-templated transcription, initiation
FOC09_RS21655	COG4824	toxin secretion phage lysis holin
FOC09_RS21660	COG3409	Peptidoglycan-binding domain 1 protein
FOC09_RS21660	COG1388	LysM domain
FOC09_RS21660	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS21690	COG1695	Transcriptional regulator
FOC09_RS21710	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC09_RS21730	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC09_RS21735	COG3639	organic phosphonate transmembrane transporter activity
FOC09_RS21765	COG1132	(ABC) transporter
FOC09_RS21770	COG1132	(ABC) transporter
FOC09_RS21785	COG3409	Peptidoglycan-binding domain 1 protein
FOC09_RS21785	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS21810	COG1346	cytolysis
FOC09_RS21815	COG1380	Effector of murein hydrolase LrgA
FOC09_RS21820	COG0583	DNA-binding transcription factor activity
FOC09_RS21830	COG0785	Cytochrome C biogenesis protein
FOC09_RS21835	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC09_RS21885	COG2226	methyltransferase
FOC09_RS21910	COG0010	Belongs to the arginase family
FOC09_RS21915	COG1329	Transcriptional regulator
FOC09_RS21920	COG1902	pentaerythritol trinitrate reductase activity
FOC09_RS21925	COG0069	glutamate synthase activity
FOC09_RS21930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC09_RS21935	COG0346	lactoylglutathione lyase activity
FOC09_RS21940	COG0400	carboxylic ester hydrolase activity
FOC09_RS21945	COG5002	protein histidine kinase activity
FOC09_RS21955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS22005	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS22010	COG1268	BioY protein
FOC09_RS22015	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS22020	COG0183	Belongs to the thiolase family
FOC09_RS22035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC09_RS22065	COG0726	polysaccharide deacetylase
FOC09_RS22075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC09_RS22080	COG2274	protein secretion by the type I secretion system
FOC09_RS22090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC09_RS22120	COG0824	Thioesterase
FOC09_RS22125	COG4841	protein insertion into membrane
FOC09_RS22130	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC09_RS22145	COG0745	RESPONSE REGULATOR receiver
FOC09_RS22150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC09_RS22155	COG1832	CoA-binding protein
FOC09_RS22160	COG0187	DNA topoisomerase II activity
FOC09_RS22165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC09_RS22170	COG0673	inositol 2-dehydrogenase activity
FOC09_RS22180	COG1131	(ABC) transporter
FOC09_RS22195	COG1595	DNA-templated transcription, initiation
FOC09_RS22205	COG1316	TRANSCRIPTIONal
FOC09_RS22215	COG4166	transmembrane transport
FOC09_RS22220	COG4166	transmembrane transport
FOC09_RS22225	COG4166	transmembrane transport
FOC09_RS22230	COG2226	methyltransferase
FOC09_RS22270	COG0697	spore germination
FOC09_RS22275	COG3383	formate dehydrogenase (NAD+) activity
FOC09_RS22280	COG2427	Protein of unknown function (DUF1641)
FOC09_RS22285	COG5609	conserved protein (DUF2294)
FOC09_RS22290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC09_RS22300	COG2116	formate transmembrane transporter activity
FOC09_RS22305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC09_RS22310	COG0303	'Molybdopterin
FOC09_RS22315	COG0314	molybdopterin synthase activity
FOC09_RS22325	COG0489	protein tyrosine kinase activity
FOC09_RS22340	COG3326	Membrane
FOC09_RS22345	COG2962	Rard protein
FOC09_RS22350	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC09_RS22355	COG1657	PFAM Prenyltransferase squalene oxidase
FOC09_RS22365	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS22370	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS22380	COG4145	pantothenate transmembrane transporter activity
FOC09_RS22395	COG0165	Argininosuccinate lyase
FOC09_RS22405	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS22435	COG0716	FMN binding
FOC09_RS22445	COG1278	Cold shock
FOC09_RS22470	COG2720	vancomycin resistance protein
FOC09_RS22475	COG2514	catechol 2,3-dioxygenase activity
FOC09_RS22490	COG1285	pathogenesis
FOC09_RS22500	COG1024	Enoyl-CoA hydratase
FOC09_RS22505	COG1216	Glycosyl transferase, family 2
FOC09_RS22535	COG0277	FAD linked oxidase domain protein
FOC09_RS22540	COG0385	Bile acid
FOC09_RS22550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC09_RS22555	COG2808	Putative FMN-binding domain
FOC09_RS22575	COG0604	alcohol dehydrogenase
FOC09_RS22580	COG0640	Transcriptional regulator
FOC09_RS22605	COG0584	glycerophosphoryl diester phosphodiesterase
FOC09_RS22635	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC09_RS22640	COG1164	Oligoendopeptidase f
FOC09_RS22660	COG1193	negative regulation of DNA recombination
FOC09_RS22680	COG0583	DNA-binding transcription factor activity
FOC09_RS22710	COG0384	phenazine biosynthesis protein PhzF
FOC09_RS22715	COG3739	integral membrane protein
FOC09_RS22720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS22725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC09_RS22730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS22750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC09_RS22755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC09_RS22785	COG2814	Major facilitator Superfamily
FOC09_RS22790	COG1113	amino acid transport
FOC09_RS22830	COG2072	flavoprotein involved in K transport
FOC09_RS22865	COG3409	Peptidoglycan-binding domain 1 protein
FOC09_RS22865	COG3757	hydrolase, family 25
FOC09_RS22870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS22880	COG1151	hydroxylamine reductase activity
FOC09_RS22905	COG3152	Membrane
FOC09_RS22925	COG1309	transcriptional regulator
FOC09_RS22940	COG1191	sigma factor activity
FOC09_RS22975	COG1733	regulation of RNA biosynthetic process
FOC09_RS22985	COG0318	PFAM AMP-dependent synthetase and ligase
FOC09_RS22995	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS23005	COG0384	phenazine biosynthesis protein PhzF
FOC09_RS23025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS23040	COG1733	regulation of RNA biosynthetic process
FOC09_RS23045	COG1733	regulation of RNA biosynthetic process
FOC09_RS23050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC09_RS23060	COG2188	Transcriptional regulator
FOC09_RS23065	COG1733	regulation of RNA biosynthetic process
FOC09_RS23070	COG1393	Belongs to the ArsC family
FOC09_RS23095	COG0814	amino acid
FOC09_RS23100	COG0346	lactoylglutathione lyase activity
FOC09_RS23115	COG2814	Major facilitator Superfamily
FOC09_RS23120	COG0656	L-ascorbic acid biosynthetic process
FOC09_RS23145	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS23160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC09_RS23165	COG0604	alcohol dehydrogenase
FOC09_RS23170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC09_RS23175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC09_RS23185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC09_RS23190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC09_RS23200	COG1070	Carbohydrate kinase
FOC09_RS23205	COG2706	6-phosphogluconolactonase activity
FOC09_RS23210	COG3813	Protein conserved in bacteria
FOC09_RS23215	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC09_RS23220	COG0697	spore germination
FOC09_RS23225	COG0789	Transcriptional regulator
FOC09_RS23230	COG1253	flavin adenine dinucleotide binding
FOC09_RS23260	COG0477	Major facilitator Superfamily
FOC09_RS23270	COG2226	methyltransferase
FOC09_RS23285	COG0628	permease
FOC09_RS23290	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC09_RS23295	COG0180	Tryptophanyl-tRNA synthetase
FOC09_RS23300	COG1136	(ABC) transporter
FOC09_RS23310	COG0110	maltose O-acetyltransferase activity
FOC09_RS23315	COG0738	Major facilitator superfamily
FOC09_RS23320	COG1940	carbohydrate kinase activity
FOC09_RS23325	COG0346	lactoylglutathione lyase activity
FOC09_RS23360	COG1011	Hydrolase
FOC09_RS23385	COG1131	(ABC) transporter
FOC09_RS23395	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS23415	COG0778	Nitroreductase
FOC09_RS23420	COG1733	regulation of RNA biosynthetic process
FOC09_RS23435	COG0124	histidyl-tRNA synthetase
FOC09_RS23440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC09_RS23445	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC09_RS23450	COG3620	sequence-specific DNA binding
FOC09_RS23465	COG2356	endonuclease I
FOC09_RS23470	COG1288	antiporter activity
FOC09_RS23475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC09_RS23490	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC09_RS23495	COG1122	ATPase activity
FOC09_RS23525	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC09_RS23535	COG2031	fatty acid transporter
FOC09_RS23545	COG1309	transcriptional regulator
FOC09_RS23550	COG2076	Multidrug Resistance protein
FOC09_RS23570	COG1131	(ABC) transporter
FOC09_RS23575	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC09_RS23590	COG2814	Major facilitator Superfamily
FOC09_RS23595	COG1846	Transcriptional regulator
FOC09_RS23605	COG0477	Major facilitator Superfamily
FOC09_RS23655	COG2207	Transcriptional regulator
FOC09_RS23655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC09_RS23660	COG0662	Cupin 2, conserved barrel domain protein
FOC09_RS23675	COG1595	DNA-templated transcription, initiation
FOC09_RS23695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC09_RS23710	COG0531	amino acid
FOC09_RS23715	COG1522	sequence-specific DNA binding
FOC09_RS23720	COG1335	isochorismatase
FOC09_RS23730	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC09_RS23735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC09_RS23745	COG1760	l-serine dehydratase
FOC09_RS23750	COG1760	l-serine dehydratase
FOC09_RS23755	COG0814	amino acid
FOC09_RS23770	COG1309	transcriptional regulator
FOC09_RS23775	COG2814	Major facilitator Superfamily
FOC09_RS23795	COG0534	Mate efflux family protein
FOC09_RS23825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC09_RS23840	COG0457	Tetratricopeptide repeat
FOC09_RS23845	COG1609	Transcriptional regulator
FOC09_RS23855	COG0561	phosphatase activity
FOC09_RS23860	COG0673	inositol 2-dehydrogenase activity
FOC09_RS23865	COG0738	Major facilitator superfamily
FOC09_RS23885	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC09_RS23895	COG0583	DNA-binding transcription factor activity
FOC09_RS23905	COG1139	Iron-sulfur cluster binding protein
FOC09_RS23910	COG1556	Lactate utilization protein
FOC09_RS23915	COG2271	Major facilitator Superfamily
FOC09_RS23920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC09_RS23925	COG2808	Putative FMN-binding domain
FOC09_RS23935	COG1846	Transcriptional regulator
FOC09_RS23940	COG2364	Membrane
FOC09_RS23950	COG5002	protein histidine kinase activity
FOC09_RS23950	COG3850	Histidine kinase
FOC09_RS23965	COG0577	efflux transmembrane transporter activity
FOC09_RS23970	COG1136	(ABC) transporter
FOC09_RS23985	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC09_RS23990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC09_RS24000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC09_RS24005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS24020	COG1476	TRANSCRIPTIONal
FOC09_RS24040	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC09_RS24065	COG5002	protein histidine kinase activity
FOC09_RS24065	COG3850	Histidine kinase
FOC09_RS24070	COG0745	RESPONSE REGULATOR receiver
FOC09_RS24095	COG2814	Major facilitator Superfamily
FOC09_RS24135	COG2169	Transcriptional regulator
FOC09_RS24160	COG0346	lactoylglutathione lyase activity
FOC09_RS24175	COG1522	sequence-specific DNA binding
FOC09_RS24190	COG0443	Heat shock 70 kDa protein
FOC09_RS24205	COG0640	Transcriptional regulator
FOC09_RS24210	COG0346	lactoylglutathione lyase activity
FOC09_RS24215	COG0798	PFAM Bile acid sodium symporter
FOC09_RS24245	COG1121	(ABC) transporter
FOC09_RS24250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC09_RS24255	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC09_RS24260	COG2267	carboxylic ester hydrolase activity
FOC09_RS24265	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC09_RS24280	COG5609	conserved protein (DUF2294)
FOC09_RS24285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC09_RS24295	COG0288	reversible hydration of carbon dioxide
FOC09_RS24300	COG0415	Belongs to the DNA photolyase family
FOC09_RS24340	COG1846	Transcriptional regulator
FOC09_RS24345	COG0583	DNA-binding transcription factor activity
FOC09_RS24365	COG1335	isochorismatase
FOC09_RS24370	COG2267	carboxylic ester hydrolase activity
FOC09_RS24375	COG0753	catalase activity
FOC09_RS24380	COG0737	Belongs to the 5'-nucleotidase family
FOC09_RS24415	COG2066	Belongs to the glutaminase family
FOC09_RS24425	COG0784	Response regulator, receiver
FOC09_RS24450	COG0281	malic enzyme
FOC09_RS24460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC09_RS24465	COG1114	Component of the transport system for branched-chain amino acids
FOC09_RS24470	COG0531	amino acid
FOC09_RS24475	COG0322	excinuclease ABC activity
FOC09_RS24485	COG1396	sequence-specific DNA binding
FOC09_RS24490	COG0252	asparaginase activity
FOC09_RS24495	COG1027	Aspartate ammonia-lyase
FOC09_RS24510	COG1063	alcohol dehydrogenase
FOC09_RS24540	COG1280	lysine exporter protein (LysE YggA)
FOC09_RS24545	COG3403	YqcI/YcgG family
FOC09_RS24550	COG5577	PFAM Coat F domain
FOC09_RS24565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC09_RS24570	COG3848	Pyruvate phosphate dikinase
FOC09_RS24570	COG0574	Belongs to the PEP-utilizing enzyme family
FOC09_RS24585	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC09_RS24615	COG1960	acyl-CoA dehydrogenase activity
FOC09_RS24625	COG0640	Transcriptional regulator
FOC09_RS24630	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC09_RS24645	COG1414	Transcriptional regulator
FOC09_RS24650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC09_RS24655	COG1984	allophanate hydrolase subunit 2
FOC09_RS24685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC09_RS24730	COG4335	DNA alkylation repair
FOC09_RS24740	COG0833	amino acid
FOC09_RS24750	COG0730	response to heat
FOC09_RS24780	COG0596	Alpha beta hydrolase
FOC09_RS24785	COG0745	RESPONSE REGULATOR receiver
FOC09_RS24790	COG0642	Histidine kinase
FOC09_RS24810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS24830	COG0456	acetyltransferase
FOC09_RS24835	COG2207	Transcriptional regulator
FOC09_RS24860	COG0577	efflux transmembrane transporter activity
FOC09_RS24860	COG1136	(ABC) transporter
FOC09_RS24870	COG1725	Transcriptional regulator
FOC09_RS24905	COG1846	Transcriptional regulator
FOC09_RS24910	COG0778	Nitroreductase
FOC09_RS24920	COG0714	Associated with various cellular activities
FOC09_RS24945	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC09_RS24955	COG0753	catalase activity
FOC09_RS24960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC09_RS24970	COG0463	Glycosyl transferase, family 2
FOC09_RS24995	COG0463	Glycosyl transferase, family 2
FOC09_RS25020	COG0714	Associated with various cellular activities
FOC09_RS25040	COG0346	lactoylglutathione lyase activity
FOC09_RS25045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS25055	COG3279	Response regulator of the LytR AlgR family
FOC09_RS25065	COG4377	Putative membrane peptidase family (DUF2324)
FOC09_RS25080	COG3655	Transcriptional regulator
FOC09_RS25090	COG1785	Belongs to the alkaline phosphatase family
FOC09_RS25095	COG3239	Fatty acid desaturase
FOC09_RS25100	COG1690	Belongs to the RtcB family
FOC09_RS25105	COG0833	amino acid
FOC09_RS25110	COG1414	Transcriptional regulator
FOC09_RS25115	COG4187	Peptidase family M20/M25/M40
FOC09_RS25120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC09_RS25125	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC09_RS25135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC09_RS25155	COG2329	Antibiotic biosynthesis monooxygenase
FOC09_RS25190	COG2390	Transcriptional regulator
FOC09_RS25200	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC09_RS25210	COG1879	ABC-type sugar transport system periplasmic component
FOC09_RS25235	COG1595	DNA-templated transcription, initiation
FOC09_RS25245	COG3584	3D domain protein
FOC09_RS25245	COG1388	LysM domain
FOC09_RS25280	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC09_RS25280	COG1605	Chorismate mutase
FOC09_RS25285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC09_RS25290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC09_RS25295	COG0287	Prephenate dehydrogenase
FOC09_RS25310	COG1309	transcriptional regulator
FOC09_RS25315	COG2409	Drug exporters of the RND superfamily
FOC09_RS25315	COG1033	growth of symbiont in host cell
FOC09_RS25320	COG2409	Drug exporters of the RND superfamily
FOC09_RS25320	COG1033	growth of symbiont in host cell
FOC09_RS25325	COG2409	Drug exporters of the RND superfamily
FOC09_RS25325	COG1033	growth of symbiont in host cell
FOC09_RS25335	COG0488	(ABC) transporter
FOC09_RS25340	COG1368	sulfuric ester hydrolase activity
FOC09_RS25345	COG0861	Integral membrane protein TerC family
FOC09_RS25355	COG0726	polysaccharide deacetylase
FOC09_RS25365	COG4912	Dna alkylation repair
FOC09_RS25385	COG2318	DinB family
FOC09_RS25390	COG0697	spore germination
FOC09_RS25415	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC09_RS25455	COG1116	anion transmembrane transporter activity
FOC09_RS25460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC09_RS25465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC09_RS25470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC09_RS25480	COG0628	permease
FOC09_RS25540	COG5146	pantothenate kinase activity
FOC09_RS25545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC09_RS25550	COG0436	Aminotransferase
FOC09_RS25585	COG2226	methyltransferase
FOC09_RS25600	COG2261	transglycosylase associated protein
FOC09_RS25620	COG2814	Major facilitator Superfamily
FOC09_RS25620	COG0477	Major facilitator Superfamily
FOC09_RS25625	COG4533	DNA binding
FOC09_RS25630	COG0789	Transcriptional regulator
FOC09_RS25635	COG1664	Polymer-forming cytoskeletal
FOC09_RS25645	COG2814	Major facilitator Superfamily
FOC09_RS25665	COG1307	EDD domain protein, DegV family
FOC09_RS25680	COG1164	Oligoendopeptidase f
FOC09_RS25720	COG5002	protein histidine kinase activity
FOC09_RS25725	COG2936	dipeptidyl-peptidase activity
FOC09_RS25770	COG4948	Mandelate Racemase Muconate Lactonizing
FOC09_RS25780	COG4166	transmembrane transport
FOC09_RS25785	COG0519	Catalyzes the synthesis of GMP from XMP
FOC09_RS25790	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC09_RS25805	COG0586	Pfam SNARE associated Golgi protein
FOC09_RS25845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC09_RS25850	COG3938	Belongs to the proline racemase family
FOC09_RS25860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC09_RS25865	COG1012	belongs to the aldehyde dehydrogenase family
FOC09_RS25870	COG1115	amino acid carrier protein
FOC09_RS25875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC09_RS25890	COG3397	chitin binding
FOC09_RS25915	COG4637	Psort location Cytoplasmic, score
FOC09_RS25935	COG0514	ATP-dependent DNA helicase (RecQ)
FOC09_RS25940	COG2105	PFAM AIG2 family protein
FOC09_RS25955	COG3973	AAA domain
FOC09_RS26005	COG2333	competence protein COMEC
FOC09_RS26005	COG0658	competence protein
FOC09_RS26025	COG2205	protein histidine kinase activity
FOC09_RS26040	COG3397	chitin binding
FOC09_RS26045	COG2153	protein acetylation
FOC09_RS26050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC09_RS26065	COG0740	serine-type endopeptidase activity
FOC09_RS26075	COG0517	IMP dehydrogenase activity
FOC09_RS26075	COG4175	Glycine betaine
FOC09_RS26080	COG4176	ABC-type proline glycine betaine transport system permease component
FOC09_RS26110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC09_RS26110	COG0456	acetyltransferase
FOC09_RS26115	COG1028	Short-chain dehydrogenase reductase Sdr
FOC09_RS26125	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC09_RS26130	COG0022	dehydrogenase e1 component
FOC09_RS26135	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC09_RS26140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC09_RS26155	COG1959	2 iron, 2 sulfur cluster binding
FOC09_RS26175	COG1349	DNA-binding transcription factor activity
FOC09_RS26190	COG3284	Transcriptional regulator
FOC09_RS26220	COG1309	transcriptional regulator
FOC09_RS26225	COG3844	kynureninase activity
FOC09_RS26230	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC09_RS26235	COG3483	tryptophan 2,3-dioxygenase activity
FOC09_RS26250	COG3773	Cell wall hydrolase
FOC09_RS26250	COG3409	Peptidoglycan-binding domain 1 protein
FOC09_RS26255	COG2959	enzyme of heme biosynthesis
FOC09_RS26270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC09_RS26275	COG4129	membrane
FOC09_RS26305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS26310	COG0697	spore germination
FOC09_RS26320	COG0201	protein transport
FOC09_RS26340	COG3227	Zinc metalloprotease (Elastase)
FOC09_RS26345	COG1523	belongs to the glycosyl hydrolase 13 family
FOC09_RS26360	COG0076	glutamate decarboxylase activity
FOC09_RS26380	COG1011	Hydrolase
FOC09_RS26405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC09_RS26445	COG0322	excinuclease ABC activity
FOC09_RS26460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC09_RS26510	COG3878	Protein conserved in bacteria
FOC09_RS26545	COG1051	belongs to the nudix hydrolase family
FOC09_RS26550	COG0592	DNA-directed DNA polymerase activity
FOC09_RS26555	COG2816	NAD+ diphosphatase activity
FOC09_RS26570	COG2223	nitrite transmembrane transporter activity
FOC09_RS26600	COG0697	spore germination
FOC09_RS26620	COG0584	glycerophosphoryl diester phosphodiesterase
FOC09_RS26635	COG2814	Major facilitator Superfamily
FOC09_RS26665	COG0693	protein deglycase activity
FOC09_RS26700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC09_RS26715	COG0604	alcohol dehydrogenase
FOC09_RS26730	COG2205	protein histidine kinase activity
FOC09_RS26745	COG1122	ATPase activity
FOC09_RS26755	COG1794	racemase activity, acting on amino acids and derivatives
FOC09_RS26760	COG1819	glycosyl
FOC09_RS26770	COG5002	protein histidine kinase activity
FOC09_RS26780	COG0561	phosphatase activity
FOC09_RS26815	COG2124	cytochrome p450
FOC09_RS26880	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC09_RS26890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS26895	COG0460	homoserine dehydrogenase
FOC09_RS26920	COG1136	(ABC) transporter
FOC09_RS26950	COG0745	RESPONSE REGULATOR receiver
FOC09_RS26960	COG3773	Cell wall hydrolase
FOC09_RS26985	COG1063	alcohol dehydrogenase
FOC09_RS27000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC09_RS27020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC09_RS27035	COG2814	Major facilitator Superfamily
FOC09_RS27045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC09_RS27060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC09_RS27060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate