locus-tag	class	description
FOC13_RS00010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS00045	COG1073	alpha beta
FOC13_RS00065	COG0427	acetyl-CoA hydrolase
FOC13_RS00070	COG3279	Response regulator of the LytR AlgR family
FOC13_RS00080	COG3384	dioxygenase
FOC13_RS00085	COG2814	Major facilitator Superfamily
FOC13_RS00110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC13_RS00120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC13_RS00125	COG0440	acetolactate synthase activity
FOC13_RS00130	COG0028	Belongs to the TPP enzyme family
FOC13_RS00135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC13_RS00145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC13_RS00160	COG2084	Dehydrogenase
FOC13_RS00175	COG2323	membrane
FOC13_RS00180	COG5566	PFAM Mor transcription activator
FOC13_RS00190	COG0733	neurotransmitter:sodium symporter activity
FOC13_RS00195	COG2244	polysaccharide biosynthetic process
FOC13_RS00210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC13_RS00215	COG2223	nitrite transmembrane transporter activity
FOC13_RS00235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC13_RS00250	COG1966	Carbon starvation protein
FOC13_RS00275	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS00280	COG1051	belongs to the nudix hydrolase family
FOC13_RS00330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC13_RS00335	COG0784	Response regulator, receiver
FOC13_RS00340	COG4191	Histidine kinase
FOC13_RS00345	COG0281	malic enzyme
FOC13_RS00350	COG1027	Aspartate ammonia-lyase
FOC13_RS00360	COG0528	UMP kinase activity
FOC13_RS00365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC13_RS00380	COG1131	(ABC) transporter
FOC13_RS00415	COG2733	membrane
FOC13_RS00445	COG0785	Cytochrome C biogenesis protein
FOC13_RS00465	COG3340	Belongs to the peptidase S51 family
FOC13_RS00490	COG0114	fumarate hydratase activity
FOC13_RS00495	COG1757	Na H antiporter
FOC13_RS00500	COG1216	Glycosyl transferase, family 2
FOC13_RS00500	COG0438	transferase activity, transferring glycosyl groups
FOC13_RS00510	COG0701	Predicted permease
FOC13_RS00515	COG0523	cobalamin synthesis protein
FOC13_RS00520	COG0697	spore germination
FOC13_RS00525	COG1802	Transcriptional regulator
FOC13_RS00555	COG0367	asparagine synthase
FOC13_RS00585	COG0406	alpha-ribazole phosphatase activity
FOC13_RS00595	COG1686	Belongs to the peptidase S11 family
FOC13_RS00625	COG1234	tRNA 3'-trailer cleavage
FOC13_RS00630	COG1177	transmembrane transport
FOC13_RS00635	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC13_RS00640	COG3842	ATPase activity
FOC13_RS00670	COG2329	Antibiotic biosynthesis monooxygenase
FOC13_RS00690	COG1309	transcriptional regulator
FOC13_RS00715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC13_RS00720	COG4786	Flagellar basal body rod
FOC13_RS00730	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC13_RS00735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC13_RS00745	COG1987	bacterial-type flagellum assembly
FOC13_RS00750	COG1338	Plays a role in the flagellum-specific transport system
FOC13_RS00760	COG1776	CheC inhibitor of MCP methylation
FOC13_RS00760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC13_RS00775	COG0741	lytic transglycosylase activity
FOC13_RS00780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC13_RS00815	COG0463	Glycosyl transferase, family 2
FOC13_RS00865	COG1157	protein secretion by the type III secretion system
FOC13_RS00875	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC13_RS00885	COG1677	Flagellar hook-basal body complex protein FliE
FOC13_RS00890	COG1558	bacterial-type flagellum-dependent cell motility
FOC13_RS00895	COG1815	bacterial-type flagellum-dependent cell motility
FOC13_RS00920	COG1256	bacterial-type flagellum assembly
FOC13_RS00940	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC13_RS00955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC13_RS00955	COG1776	CheC inhibitor of MCP methylation
FOC13_RS00965	COG2201	protein-glutamate methylesterase activity
FOC13_RS00970	COG1360	Flagellar Motor Protein
FOC13_RS00975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC13_RS00985	COG1923	regulation of RNA biosynthetic process
FOC13_RS01040	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC13_RS01045	COG2323	membrane
FOC13_RS01055	COG0789	Transcriptional regulator
FOC13_RS01055	COG4978	Transcriptional regulator
FOC13_RS01065	COG0475	glutathione-regulated potassium exporter activity
FOC13_RS01075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC13_RS01080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC13_RS01085	COG3162	membrane
FOC13_RS01100	COG1280	lysine exporter protein (LysE YggA)
FOC13_RS01140	COG0328	RNA-DNA hybrid ribonuclease activity
FOC13_RS01160	COG0454	-acetyltransferase
FOC13_RS01180	COG1215	transferase activity, transferring glycosyl groups
FOC13_RS01195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC13_RS01220	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC13_RS01270	COG0456	acetyltransferase
FOC13_RS01280	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC13_RS01285	COG2311	Membrane
FOC13_RS01290	COG2233	PERMEase
FOC13_RS01305	COG0024	Methionine aminopeptidase
FOC13_RS01310	COG3173	Aminoglycoside phosphotransferase
FOC13_RS01320	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC13_RS01325	COG1199	ATP-dependent helicase activity
FOC13_RS01335	COG0116	Belongs to the methyltransferase superfamily
FOC13_RS01350	COG4474	Belongs to the UPF0398 family
FOC13_RS01390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC13_RS01390	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC13_RS01400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC13_RS01405	COG3935	DnaD domain protein
FOC13_RS01425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC13_RS01425	COG1199	ATP-dependent helicase activity
FOC13_RS01460	COG0438	transferase activity, transferring glycosyl groups
FOC13_RS01465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC13_RS01480	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC13_RS01485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS01495	COG2738	Putative neutral zinc metallopeptidase
FOC13_RS01510	COG4347	Protein of unknown function (DUF1405)
FOC13_RS01520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC13_RS01540	COG0457	Tetratricopeptide repeat
FOC13_RS01545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC13_RS01560	COG0105	UTP biosynthetic process
FOC13_RS01565	COG0142	geranyltranstransferase activity
FOC13_RS01575	COG0142	geranyltranstransferase activity
FOC13_RS01590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC13_RS01665	COG0492	ferredoxin-NADP+ reductase activity
FOC13_RS01685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC13_RS01690	COG4862	establishment of competence for transformation
FOC13_RS01710	COG1266	CAAX protease self-immunity
FOC13_RS01715	COG0514	ATP-dependent DNA helicase (RecQ)
FOC13_RS01720	COG4955	Helix-turn-helix domain
FOC13_RS01725	COG1141	Ferredoxin
FOC13_RS01730	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC13_RS01745	COG2096	Adenosyltransferase
FOC13_RS01750	COG5002	protein histidine kinase activity
FOC13_RS01755	COG0745	RESPONSE REGULATOR receiver
FOC13_RS01760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC13_RS01765	COG1333	cytochrome c biogenesis protein
FOC13_RS01775	COG1187	pseudouridine synthase activity
FOC13_RS01780	COG0700	Nucleoside recognition
FOC13_RS01785	COG2715	membrane protein required for spore maturation
FOC13_RS01790	COG1686	Belongs to the peptidase S11 family
FOC13_RS01795	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC13_RS01810	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC13_RS01810	COG0392	lysyltransferase activity
FOC13_RS01830	COG5002	protein histidine kinase activity
FOC13_RS01835	COG0582	viral genome integration into host DNA
FOC13_RS01845	COG1801	Protein of unknown function DUF72
FOC13_RS01865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC13_RS01870	COG1392	Phosphate transport regulator
FOC13_RS01875	COG0306	phosphate transporter
FOC13_RS01880	COG0730	response to heat
FOC13_RS01895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC13_RS01895	COG1017	nitric oxide dioxygenase activity
FOC13_RS01920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC13_RS01930	COG1114	Component of the transport system for branched-chain amino acids
FOC13_RS01940	COG2197	response regulator
FOC13_RS01945	COG4585	Histidine kinase
FOC13_RS01950	COG4758	membrane
FOC13_RS01965	COG1757	Na H antiporter
FOC13_RS01985	COG0733	neurotransmitter:sodium symporter activity
FOC13_RS01990	COG1648	precorrin-2 dehydrogenase activity
FOC13_RS02010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC13_RS02015	COG0529	Catalyzes the synthesis of activated sulfate
FOC13_RS02035	COG0019	diaminopimelate decarboxylase activity
FOC13_RS02045	COG1368	sulfuric ester hydrolase activity
FOC13_RS02050	COG1183	phosphatidylcholine synthase activity
FOC13_RS02065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC13_RS02100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC13_RS02125	COG0473	3-isopropylmalate dehydrogenase activity
FOC13_RS02135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC13_RS02140	COG0440	acetolactate synthase activity
FOC13_RS02145	COG0028	Belongs to the TPP enzyme family
FOC13_RS02150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC13_RS02175	COG3874	Sporulation protein YtfJ
FOC13_RS02180	COG4709	membrane
FOC13_RS02185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC13_RS02190	COG1301	dicarboxylic acid transport
FOC13_RS02200	COG1846	Transcriptional regulator
FOC13_RS02215	COG1968	undecaprenyl-diphosphatase activity
FOC13_RS02220	COG0534	Mate efflux family protein
FOC13_RS02235	COG3173	Aminoglycoside phosphotransferase
FOC13_RS02245	COG0716	FMN binding
FOC13_RS02265	COG1696	Membrane protein involved in D-alanine export
FOC13_RS02275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC13_RS02280	COG2070	2-Nitropropane dioxygenase
FOC13_RS02285	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC13_RS02295	COG1335	isochorismatase
FOC13_RS02305	COG1522	sequence-specific DNA binding
FOC13_RS02320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC13_RS02325	COG1131	(ABC) transporter
FOC13_RS02335	COG1131	(ABC) transporter
FOC13_RS02340	COG1725	Transcriptional regulator
FOC13_RS02345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC13_RS02365	COG1780	Probably involved in ribonucleotide reductase function
FOC13_RS02390	COG4873	Protein conserved in bacteria
FOC13_RS02405	COG0720	synthase
FOC13_RS02415	COG5002	protein histidine kinase activity
FOC13_RS02420	COG2318	DinB family
FOC13_RS02430	COG1846	Transcriptional regulator
FOC13_RS02435	COG3852	Histidine kinase
FOC13_RS02445	COG2861	carbohydrate metabolic process
FOC13_RS02465	COG1349	DNA-binding transcription factor activity
FOC13_RS02480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC13_RS02495	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC13_RS02505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC13_RS02515	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC13_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS02540	COG2030	dehydratase
FOC13_RS02550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC13_RS02555	COG0861	Integral membrane protein TerC family
FOC13_RS02560	COG2116	formate transmembrane transporter activity
FOC13_RS02570	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC13_RS02590	COG2186	Transcriptional regulator
FOC13_RS02595	COG5002	protein histidine kinase activity
FOC13_RS02600	COG0745	RESPONSE REGULATOR receiver
FOC13_RS02610	COG3835	regulator
FOC13_RS02615	COG0277	FAD linked oxidase domain protein
FOC13_RS02620	COG0247	lactate metabolic process
FOC13_RS02625	COG2340	Cysteine-rich secretory protein family
FOC13_RS02635	COG0564	pseudouridine synthase activity
FOC13_RS02645	COG2409	Drug exporters of the RND superfamily
FOC13_RS02655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC13_RS02660	COG1177	transmembrane transport
FOC13_RS02665	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC13_RS02670	COG3842	ATPase activity
FOC13_RS02675	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS02710	COG0681	Belongs to the peptidase S26 family
FOC13_RS02715	COG1686	Belongs to the peptidase S11 family
FOC13_RS02725	COG2226	methyltransferase
FOC13_RS02785	COG1476	TRANSCRIPTIONal
FOC13_RS02795	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC13_RS02850	COG5634	Uncharacterized conserved protein (DUF2278)
FOC13_RS02855	COG1620	l-lactate permease
FOC13_RS02890	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC13_RS02890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC13_RS02900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC13_RS02905	COG5492	domain, Protein
FOC13_RS02920	COG2382	esterase
FOC13_RS02925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC13_RS02930	COG2153	protein acetylation
FOC13_RS02975	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC13_RS02990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC13_RS03010	COG0457	Tetratricopeptide repeat
FOC13_RS03010	COG0463	Glycosyl transferase, family 2
FOC13_RS03030	COG1216	Glycosyl transferase, family 2
FOC13_RS03050	COG0564	pseudouridine synthase activity
FOC13_RS03055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC13_RS03060	COG2357	RelA SpoT domain protein
FOC13_RS03070	COG4116	CYTH
FOC13_RS03075	COG2346	COG2346, Truncated hemoglobins
FOC13_RS03085	COG1164	Oligoendopeptidase f
FOC13_RS03095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC13_RS03100	COG4862	establishment of competence for transformation
FOC13_RS03105	COG0861	Integral membrane protein TerC family
FOC13_RS03110	COG1393	Belongs to the ArsC family
FOC13_RS03120	COG4166	transmembrane transport
FOC13_RS03125	COG0534	Mate efflux family protein
FOC13_RS03130	COG4608	Belongs to the ABC transporter superfamily
FOC13_RS03135	COG0444	Belongs to the ABC transporter superfamily
FOC13_RS03140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC13_RS03145	COG0601	transmembrane transport
FOC13_RS03150	COG4166	transmembrane transport
FOC13_RS03160	COG0180	Tryptophanyl-tRNA synthetase
FOC13_RS03170	COG5504	Zn-dependent protease
FOC13_RS03175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC13_RS03180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC13_RS03195	COG2267	carboxylic ester hydrolase activity
FOC13_RS03205	COG0542	response to heat
FOC13_RS03215	COG0561	phosphatase activity
FOC13_RS03230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS03240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC13_RS03250	COG2996	Protein conserved in bacteria
FOC13_RS03275	COG0753	catalase activity
FOC13_RS03285	COG0367	asparagine synthase
FOC13_RS03310	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC13_RS03355	COG1074	ATP-dependent DNA helicase activity
FOC13_RS03360	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC13_RS03370	COG0398	Pfam SNARE associated Golgi protein
FOC13_RS03375	COG4903	ComK protein
FOC13_RS03390	COG1278	Cold shock
FOC13_RS03400	COG2224	Isocitrate lyase
FOC13_RS03405	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC13_RS03410	COG0497	DNA recombination
FOC13_RS03425	COG0697	spore germination
FOC13_RS03430	COG0840	transmembrane signaling receptor activity
FOC13_RS03435	COG0501	Belongs to the peptidase M48B family
FOC13_RS03460	COG0745	RESPONSE REGULATOR receiver
FOC13_RS03465	COG2205	protein histidine kinase activity
FOC13_RS03475	COG2207	Transcriptional regulator
FOC13_RS03475	COG3708	Transcriptional regulator
FOC13_RS03480	COG1595	DNA-templated transcription, initiation
FOC13_RS03490	COG1078	dGTPase activity
FOC13_RS03525	COG3209	COG3209 Rhs family protein
FOC13_RS03555	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS03565	COG0095	Lipoate-protein ligase
FOC13_RS03570	COG1234	tRNA 3'-trailer cleavage
FOC13_RS03580	COG1609	Transcriptional regulator
FOC13_RS03605	COG1511	domain protein
FOC13_RS03610	COG1309	transcriptional regulator
FOC13_RS03655	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC13_RS03660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC13_RS03665	COG2329	Antibiotic biosynthesis monooxygenase
FOC13_RS03670	COG3428	Bacterial PH domain
FOC13_RS03675	COG3402	PFAM membrane-flanked domain
FOC13_RS03720	COG3402	PFAM membrane-flanked domain
FOC13_RS03725	COG1309	transcriptional regulator
FOC13_RS03740	COG4473	ABC transporter
FOC13_RS03745	COG1131	(ABC) transporter
FOC13_RS03750	COG0537	adenosine 5'-monophosphoramidase activity
FOC13_RS03755	COG4980	gas vesicle protein
FOC13_RS03775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC13_RS03780	COG3973	AAA domain
FOC13_RS03790	COG0477	Major facilitator Superfamily
FOC13_RS03795	COG0477	Major facilitator Superfamily
FOC13_RS03830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC13_RS03840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC13_RS03845	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC13_RS03865	COG2267	carboxylic ester hydrolase activity
FOC13_RS03870	COG0457	Tetratricopeptide repeat
FOC13_RS03875	COG0346	lactoylglutathione lyase activity
FOC13_RS03880	COG0346	lactoylglutathione lyase activity
FOC13_RS03885	COG2814	Major facilitator Superfamily
FOC13_RS03890	COG1309	transcriptional regulator
FOC13_RS03915	COG0420	3'-5' exonuclease activity
FOC13_RS03945	COG0393	Putative heavy-metal-binding
FOC13_RS03965	COG2198	Histidine kinase
FOC13_RS03965	COG0784	Response regulator, receiver
FOC13_RS03965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC13_RS03965	COG2205	protein histidine kinase activity
FOC13_RS03970	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC13_RS03975	COG2208	phosphoserine phosphatase activity
FOC13_RS03985	COG1191	sigma factor activity
FOC13_RS04010	COG3237	CsbD-like
FOC13_RS04060	COG3437	response regulator, receiver
FOC13_RS04060	COG2770	Histidine kinase
FOC13_RS04090	COG1959	2 iron, 2 sulfur cluster binding
FOC13_RS04095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC13_RS04100	COG2376	Dihydroxyacetone kinase
FOC13_RS04110	COG2376	Dihydroxyacetone kinase
FOC13_RS04130	COG1183	phosphatidylcholine synthase activity
FOC13_RS04155	COG3320	Male sterility
FOC13_RS04155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC13_RS04200	COG0477	Major facilitator Superfamily
FOC13_RS04230	COG0305	Participates in initiation and elongation during chromosome replication
FOC13_RS04245	COG4978	Transcriptional regulator
FOC13_RS04245	COG0789	Transcriptional regulator
FOC13_RS04275	COG3181	Tripartite tricarboxylate transporter family receptor
FOC13_RS04280	COG4565	transcriptional regulatory protein
FOC13_RS04285	COG3290	protein histidine kinase activity
FOC13_RS04290	COG0477	Major facilitator Superfamily
FOC13_RS04320	COG0322	excinuclease ABC activity
FOC13_RS04325	COG4608	Belongs to the ABC transporter superfamily
FOC13_RS04335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC13_RS04340	COG0601	transmembrane transport
FOC13_RS04375	COG3938	Belongs to the proline racemase family
FOC13_RS04395	COG1363	Peptidase, m42
FOC13_RS04415	COG1024	Enoyl-CoA hydratase
FOC13_RS04430	COG1696	Membrane protein involved in D-alanine export
FOC13_RS04445	COG4196	transglutaminase domain protein
FOC13_RS04450	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS04460	COG2244	polysaccharide biosynthetic process
FOC13_RS04465	COG0653	protein targeting
FOC13_RS04485	COG0659	secondary active sulfate transmembrane transporter activity
FOC13_RS04500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC13_RS04515	COG0561	phosphatase activity
FOC13_RS04530	COG3527	Alpha-acetolactate decarboxylase
FOC13_RS04535	COG0028	Belongs to the TPP enzyme family
FOC13_RS04565	COG0189	ligase activity
FOC13_RS04580	COG1126	abc transporter atp-binding protein
FOC13_RS04585	COG0765	amino acid transport
FOC13_RS04590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC13_RS04600	COG1132	(ABC) transporter
FOC13_RS04605	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS04615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC13_RS04620	COG0531	amino acid
FOC13_RS04630	COG0693	protein deglycase activity
FOC13_RS04630	COG0753	catalase activity
FOC13_RS04635	COG0693	protein deglycase activity
FOC13_RS04645	COG2211	Major facilitator Superfamily
FOC13_RS04650	COG4533	DNA binding
FOC13_RS04655	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC13_RS04665	COG1733	regulation of RNA biosynthetic process
FOC13_RS04670	COG2814	Major facilitator Superfamily
FOC13_RS04675	COG1309	transcriptional regulator
FOC13_RS04680	COG2076	Multidrug Resistance protein
FOC13_RS04685	COG2076	Multidrug Resistance protein
FOC13_RS04695	COG1522	sequence-specific DNA binding
FOC13_RS04700	COG0697	spore germination
FOC13_RS04715	COG2259	Doxx family
FOC13_RS04725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC13_RS04725	COG1263	PTS System
FOC13_RS04735	COG1737	Transcriptional regulator
FOC13_RS04745	COG0475	glutathione-regulated potassium exporter activity
FOC13_RS04750	COG0531	amino acid
FOC13_RS04780	COG0586	Pfam SNARE associated Golgi protein
FOC13_RS04815	COG3546	catalase activity
FOC13_RS04820	COG1114	Component of the transport system for branched-chain amino acids
FOC13_RS04835	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC13_RS04845	COG1136	(ABC) transporter
FOC13_RS04850	COG0577	efflux transmembrane transporter activity
FOC13_RS04855	COG3584	3D domain protein
FOC13_RS04855	COG1388	LysM domain
FOC13_RS04875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC13_RS04880	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC13_RS04885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC13_RS04885	COG3711	transcriptional antiterminator
FOC13_RS04900	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC13_RS04905	COG0604	alcohol dehydrogenase
FOC13_RS04910	COG1316	TRANSCRIPTIONal
FOC13_RS04920	COG0730	response to heat
FOC13_RS04925	COG2210	Belongs to the sulfur carrier protein TusA family
FOC13_RS04935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC13_RS04940	COG0425	Belongs to the sulfur carrier protein TusA family
FOC13_RS04945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC13_RS04945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS04950	COG0425	Belongs to the sulfur carrier protein TusA family
FOC13_RS04950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC13_RS04955	COG1937	Protein conserved in bacteria
FOC13_RS04960	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC13_RS04985	COG2719	SpoVR family
FOC13_RS04990	COG0778	Nitroreductase
FOC13_RS05025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC13_RS05030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC13_RS05040	COG1609	Transcriptional regulator
FOC13_RS05045	COG1263	PTS System
FOC13_RS05045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC13_RS05050	COG1621	beta-fructofuranosidase activity
FOC13_RS05055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC13_RS05070	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS05075	COG2252	PERMEase
FOC13_RS05090	COG1846	Transcriptional regulator
FOC13_RS05095	COG2814	Major facilitator Superfamily
FOC13_RS05100	COG2205	protein histidine kinase activity
FOC13_RS05140	COG0351	phosphomethylpyrimidine kinase
FOC13_RS05145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC13_RS05155	COG2104	thiamine diphosphate biosynthetic process
FOC13_RS05160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC13_RS05165	COG0352	thiamine-phosphate diphosphorylase activity
FOC13_RS05170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC13_RS05175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC13_RS05180	COG1116	anion transmembrane transporter activity
FOC13_RS05185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC13_RS05205	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC13_RS05320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC13_RS05330	COG0581	inorganic phosphate transmembrane transporter activity
FOC13_RS05335	COG0573	inorganic phosphate transmembrane transporter activity
FOC13_RS05340	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC13_RS05345	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC13_RS05345	COG1918	ferrous iron import across plasma membrane
FOC13_RS05350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC13_RS05355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC13_RS05365	COG0531	amino acid
FOC13_RS05370	COG0697	spore germination
FOC13_RS05375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC13_RS05390	COG4990	cell redox homeostasis
FOC13_RS05395	COG0833	amino acid
FOC13_RS05400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC13_RS05405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC13_RS05420	COG0475	glutathione-regulated potassium exporter activity
FOC13_RS05420	COG0569	domain protein
FOC13_RS05445	COG2252	PERMEase
FOC13_RS05450	COG1113	amino acid transport
FOC13_RS05465	COG1114	Component of the transport system for branched-chain amino acids
FOC13_RS05470	COG3104	oligopeptide transport
FOC13_RS05485	COG1476	TRANSCRIPTIONal
FOC13_RS05490	COG1388	LysM domain
FOC13_RS05490	COG3584	3D domain protein
FOC13_RS05495	COG0840	transmembrane signaling receptor activity
FOC13_RS05500	COG1968	undecaprenyl-diphosphatase activity
FOC13_RS05525	COG3568	Endonuclease Exonuclease Phosphatase
FOC13_RS05540	COG1063	alcohol dehydrogenase
FOC13_RS05560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC13_RS05565	COG1879	ABC-type sugar transport system periplasmic component
FOC13_RS05570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC13_RS05585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC13_RS05590	COG1609	Transcriptional regulator
FOC13_RS05600	COG1846	Transcriptional regulator
FOC13_RS05605	COG2271	Major facilitator Superfamily
FOC13_RS05615	COG4608	Belongs to the ABC transporter superfamily
FOC13_RS05620	COG0601	transmembrane transport
FOC13_RS05630	COG0747	negative chemotaxis
FOC13_RS05645	COG0659	secondary active sulfate transmembrane transporter activity
FOC13_RS05660	COG5002	protein histidine kinase activity
FOC13_RS05665	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC13_RS05670	COG2378	regulation of single-species biofilm formation
FOC13_RS05695	COG0833	amino acid
FOC13_RS05700	COG0765	amino acid transport
FOC13_RS05705	COG0765	amino acid transport
FOC13_RS05710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC13_RS05715	COG1126	abc transporter atp-binding protein
FOC13_RS05720	COG1115	amino acid carrier protein
FOC13_RS05725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC13_RS05735	COG0697	spore germination
FOC13_RS05750	COG0366	Alpha amylase catalytic
FOC13_RS05755	COG1263	PTS System
FOC13_RS05755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC13_RS05760	COG2188	Transcriptional regulator
FOC13_RS05765	COG0531	amino acid
FOC13_RS05785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC13_RS05790	COG0714	Associated with various cellular activities
FOC13_RS05795	COG4548	von Willebrand factor, type A
FOC13_RS05805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC13_RS05810	COG0156	8-amino-7-oxononanoate synthase activity
FOC13_RS05815	COG2226	methyltransferase
FOC13_RS05825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS05830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS05835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS05840	COG3104	oligopeptide transport
FOC13_RS05855	COG1620	l-lactate permease
FOC13_RS05860	COG1027	Aspartate ammonia-lyase
FOC13_RS05865	COG1253	flavin adenine dinucleotide binding
FOC13_RS05870	COG0346	lactoylglutathione lyase activity
FOC13_RS05875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS05880	COG1316	TRANSCRIPTIONal
FOC13_RS05885	COG2720	vancomycin resistance protein
FOC13_RS05905	COG3227	Zinc metalloprotease (Elastase)
FOC13_RS05920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC13_RS05925	COG2217	Heavy metal translocating P-type atpase
FOC13_RS05930	COG0640	Transcriptional regulator
FOC13_RS05935	COG0531	amino acid
FOC13_RS05950	COG2427	Protein of unknown function (DUF1641)
FOC13_RS05955	COG3383	formate dehydrogenase (NAD+) activity
FOC13_RS05960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC13_RS05965	COG0456	acetyltransferase
FOC13_RS05965	COG0454	-acetyltransferase
FOC13_RS05970	COG0745	RESPONSE REGULATOR receiver
FOC13_RS05975	COG5002	protein histidine kinase activity
FOC13_RS05985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS06000	COG0281	malic enzyme
FOC13_RS06005	COG3493	citrate carrier protein
FOC13_RS06010	COG4565	transcriptional regulatory protein
FOC13_RS06015	COG3290	protein histidine kinase activity
FOC13_RS06025	COG4990	cell redox homeostasis
FOC13_RS06035	COG5002	protein histidine kinase activity
FOC13_RS06040	COG0745	RESPONSE REGULATOR receiver
FOC13_RS06045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC13_RS06055	COG0395	ABC-type sugar transport system, permease component
FOC13_RS06060	COG1175	transmembrane transport
FOC13_RS06065	COG3842	ATPase activity
FOC13_RS06070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC13_RS06090	COG2851	Citrate transporter
FOC13_RS06100	COG3290	protein histidine kinase activity
FOC13_RS06110	COG2268	Band 7 protein
FOC13_RS06115	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC13_RS06125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC13_RS06130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS06145	COG2766	serine protein kinase
FOC13_RS06155	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC13_RS06165	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC13_RS06175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC13_RS06180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC13_RS06295	COG0735	belongs to the Fur family
FOC13_RS06300	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC13_RS06320	COG4555	ABC transporter
FOC13_RS06330	COG0070	glutamate synthase
FOC13_RS06330	COG0067	glutamate synthase
FOC13_RS06330	COG0069	glutamate synthase activity
FOC13_RS06335	COG4129	membrane
FOC13_RS06340	COG1132	(ABC) transporter
FOC13_RS06365	COG1194	a g-specific adenine glycosylase
FOC13_RS06370	COG1988	membrane-bound metal-dependent
FOC13_RS06400	COG1090	epimerase
FOC13_RS06405	COG1228	amidohydrolase
FOC13_RS06425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC13_RS06445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC13_RS06445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC13_RS06460	COG0463	Glycosyl transferase, family 2
FOC13_RS06475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC13_RS06480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC13_RS06480	COG1263	PTS System
FOC13_RS06485	COG2066	Belongs to the glutaminase family
FOC13_RS06505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC13_RS06510	COG0833	amino acid
FOC13_RS06520	COG3829	transcription factor binding
FOC13_RS06530	COG0101	tRNA pseudouridine synthase activity
FOC13_RS06735	COG1484	DNA-dependent DNA replication
FOC13_RS06770	COG1396	sequence-specific DNA binding
FOC13_RS06785	COG1396	sequence-specific DNA binding
FOC13_RS06790	COG0582	viral genome integration into host DNA
FOC13_RS06795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC13_RS06800	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC13_RS06825	COG0535	radical SAM domain protein
FOC13_RS06835	COG0387	Pfam Sodium calcium exchanger
FOC13_RS06840	COG3871	stress protein (general stress protein 26)
FOC13_RS06855	COG0586	Pfam SNARE associated Golgi protein
FOC13_RS06875	COG0697	spore germination
FOC13_RS06880	COG2217	Heavy metal translocating P-type atpase
FOC13_RS06885	COG1295	ribonuclease BN
FOC13_RS06895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC13_RS06910	COG3853	Toxic anion resistance protein (TelA)
FOC13_RS06920	COG0861	Integral membrane protein TerC family
FOC13_RS06925	COG2310	stress, protein
FOC13_RS06930	COG2310	stress, protein
FOC13_RS06935	COG2310	stress, protein
FOC13_RS06950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC13_RS06965	COG2270	Major facilitator Superfamily
FOC13_RS07010	COG0488	(ABC) transporter
FOC13_RS07015	COG1116	anion transmembrane transporter activity
FOC13_RS07025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC13_RS07040	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC13_RS07070	COG2190	(PTS) system
FOC13_RS07070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC13_RS07070	COG1263	PTS System
FOC13_RS07075	COG0366	Alpha amylase catalytic
FOC13_RS07080	COG0840	transmembrane signaling receptor activity
FOC13_RS07085	COG0840	transmembrane signaling receptor activity
FOC13_RS07095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC13_RS07100	COG0765	amino acid transport
FOC13_RS07110	COG0723	plastoquinol--plastocyanin reductase activity
FOC13_RS07110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC13_RS07115	COG2814	Major facilitator Superfamily
FOC13_RS07120	COG3541	Predicted nucleotidyltransferase
FOC13_RS07140	COG5002	protein histidine kinase activity
FOC13_RS07175	COG0166	Belongs to the GPI family
FOC13_RS07190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS07195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS07200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS07205	COG0235	Class ii aldolase
FOC13_RS07215	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC13_RS07220	COG0450	alkyl hydroperoxide reductase
FOC13_RS07235	COG1473	amidohydrolase
FOC13_RS07265	COG4807	Protein conserved in bacteria
FOC13_RS07275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC13_RS07280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC13_RS07285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS07300	COG2309	aminopeptidase activity
FOC13_RS07305	COG2076	Multidrug Resistance protein
FOC13_RS07310	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS07320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC13_RS07325	COG0546	phosphoglycolate phosphatase activity
FOC13_RS07330	COG1597	lipid kinase activity
FOC13_RS07355	COG1846	Transcriptional regulator
FOC13_RS07375	COG1464	Belongs to the NlpA lipoprotein family
FOC13_RS07380	COG2011	ABC-type metal ion transport system permease component
FOC13_RS07385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC13_RS07390	COG1335	isochorismatase
FOC13_RS07405	COG4851	CamS sex pheromone cAM373 precursor
FOC13_RS07415	COG0210	DNA helicase
FOC13_RS07440	COG0151	Belongs to the GarS family
FOC13_RS07450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC13_RS07460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC13_RS07475	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC13_RS07485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC13_RS07490	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC13_RS07495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC13_RS07515	COG0745	RESPONSE REGULATOR receiver
FOC13_RS07520	COG2205	protein histidine kinase activity
FOC13_RS07535	COG1968	undecaprenyl-diphosphatase activity
FOC13_RS07575	COG2226	methyltransferase
FOC13_RS07610	COG5002	protein histidine kinase activity
FOC13_RS07620	COG2252	PERMEase
FOC13_RS07640	COG1266	CAAX protease self-immunity
FOC13_RS07655	COG0488	(ABC) transporter
FOC13_RS07660	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC13_RS07665	COG0456	acetyltransferase
FOC13_RS07670	COG1214	PFAM Peptidase M22, glycoprotease
FOC13_RS07675	COG0802	atpase or kinase
FOC13_RS07770	COG2183	response to ionizing radiation
FOC13_RS07775	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC13_RS07780	COG0864	Transcriptional regulator
FOC13_RS07785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC13_RS07790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC13_RS07800	COG0705	Rhomboid family
FOC13_RS07800	COG0457	Tetratricopeptide repeat
FOC13_RS07805	COG4294	response to UV
FOC13_RS07815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC13_RS07825	COG2814	Major facilitator Superfamily
FOC13_RS07835	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC13_RS07840	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC13_RS07860	COG4608	Belongs to the ABC transporter superfamily
FOC13_RS07865	COG0444	Belongs to the ABC transporter superfamily
FOC13_RS07875	COG0601	transmembrane transport
FOC13_RS07880	COG0747	negative chemotaxis
FOC13_RS07895	COG0488	(ABC) transporter
FOC13_RS07915	COG5298	Protein conserved in bacteria
FOC13_RS07920	COG0084	hydrolase, TatD family'
FOC13_RS07930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS07940	COG1609	Transcriptional regulator
FOC13_RS07950	COG0204	Acyl-transferase
FOC13_RS07965	COG0697	spore germination
FOC13_RS07970	COG0583	DNA-binding transcription factor activity
FOC13_RS07980	COG1910	domain protein
FOC13_RS07990	COG4149	molybdate abc transporter
FOC13_RS07995	COG4975	Glucose uptake
FOC13_RS08005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC13_RS08010	COG0656	L-ascorbic acid biosynthetic process
FOC13_RS08015	COG4166	transmembrane transport
FOC13_RS08020	COG4166	transmembrane transport
FOC13_RS08035	COG2207	Transcriptional regulator
FOC13_RS08045	COG4166	transmembrane transport
FOC13_RS08050	COG4608	Belongs to the ABC transporter superfamily
FOC13_RS08055	COG0444	Belongs to the ABC transporter superfamily
FOC13_RS08060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC13_RS08065	COG0601	transmembrane transport
FOC13_RS08080	COG2814	Major facilitator Superfamily
FOC13_RS08090	COG2271	Major facilitator Superfamily
FOC13_RS08095	COG0277	FAD linked oxidase domain protein
FOC13_RS08110	COG1464	Belongs to the NlpA lipoprotein family
FOC13_RS08115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC13_RS08120	COG2011	ABC-type metal ion transport system permease component
FOC13_RS08155	COG0823	Involved in the tonB-independent uptake of proteins
FOC13_RS08155	COG1506	peptidase
FOC13_RS08155	COG4946	Tricorn protease homolog
FOC13_RS08160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC13_RS08180	COG0596	Alpha beta hydrolase
FOC13_RS08185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC13_RS08200	COG4856	YbbR-like protein
FOC13_RS08205	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC13_RS08285	COG0726	polysaccharide deacetylase
FOC13_RS08290	COG2194	sulfuric ester hydrolase activity
FOC13_RS08300	COG0489	protein tyrosine kinase activity
FOC13_RS08305	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS08325	COG0101	tRNA pseudouridine synthase activity
FOC13_RS08330	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC13_RS08335	COG1122	ATPase activity
FOC13_RS08365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC13_RS08375	COG0024	Methionine aminopeptidase
FOC13_RS08385	COG0201	protein transport
FOC13_RS08410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC13_RS08515	COG1358	cellular component organization or biogenesis
FOC13_RS08520	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC13_RS08530	COG2813	Specifically methylates the guanine in position
FOC13_RS08555	COG0250	Participates in transcription elongation, termination and antitermination
FOC13_RS08560	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC13_RS08565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC13_RS08575	COG3688	RNA-binding protein containing a PIN domain
FOC13_RS08580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC13_RS08595	COG1045	serine acetyltransferase
FOC13_RS08615	COG4956	integral membrane protein (PIN domain superfamily)
FOC13_RS08625	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC13_RS08630	COG0542	response to heat
FOC13_RS08640	COG3880	PFAM UvrB UvrC protein
FOC13_RS08670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC13_RS08675	COG1396	sequence-specific DNA binding
FOC13_RS08680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC13_RS08685	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC13_RS08690	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC13_RS08695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC13_RS08700	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC13_RS08705	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC13_RS08710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC13_RS08725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC13_RS08735	COG0037	tRNA processing
FOC13_RS08740	COG2208	phosphoserine phosphatase activity
FOC13_RS08755	COG1098	S1 RNA binding domain
FOC13_RS08775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC13_RS08780	COG3956	TIGRFAM MazG family protein
FOC13_RS08785	COG2244	polysaccharide biosynthetic process
FOC13_RS08790	COG2002	toxin-antitoxin pair type II binding
FOC13_RS08795	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC13_RS08805	COG0193	aminoacyl-tRNA hydrolase activity
FOC13_RS08810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC13_RS08825	COG0251	oxidation-reduction process
FOC13_RS08830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC13_RS08845	COG4466	Protein conserved in bacteria
FOC13_RS08860	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC13_RS08865	COG0084	hydrolase, TatD family'
FOC13_RS08870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC13_RS08870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC13_RS08875	COG2002	toxin-antitoxin pair type II binding
FOC13_RS08880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC13_RS08890	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC13_RS08900	COG1774	PSP1 C-terminal conserved region
FOC13_RS08905	COG0470	DNA polymerase III
FOC13_RS08915	COG1982	Orn Lys Arg decarboxylase major
FOC13_RS08970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC13_RS08980	COG0590	tRNA wobble adenosine to inosine editing
FOC13_RS08985	COG1335	isochorismatase
FOC13_RS08990	COG1428	Deoxynucleoside kinase
FOC13_RS08995	COG1428	Deoxynucleoside kinase
FOC13_RS09025	COG1686	Belongs to the peptidase S11 family
FOC13_RS09030	COG0517	IMP dehydrogenase activity
FOC13_RS09030	COG0516	GMP reductase activity
FOC13_RS09065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC13_RS09070	COG0187	DNA topoisomerase II activity
FOC13_RS09080	COG2501	S4 domain
FOC13_RS09085	COG0592	DNA-directed DNA polymerase activity
FOC13_RS09105	COG0706	membrane insertase activity
FOC13_RS09110	COG1847	R3H domain protein
FOC13_RS09115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC13_RS09135	COG1192	Involved in chromosome partitioning
FOC13_RS09140	COG1475	DNA binding
FOC13_RS09150	COG0668	transmembrane transport
FOC13_RS09155	COG4481	Protein conserved in bacteria
FOC13_RS09160	COG0012	GTP binding
FOC13_RS09170	COG0629	single-stranded DNA binding
FOC13_RS09180	COG4241	membrane
FOC13_RS09185	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC13_RS09195	COG0305	Participates in initiation and elongation during chromosome replication
FOC13_RS09225	COG0745	RESPONSE REGULATOR receiver
FOC13_RS09230	COG5002	protein histidine kinase activity
FOC13_RS09235	COG4863	YycH protein
FOC13_RS09240	COG4853	Protein conserved in bacteria
FOC13_RS09245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC13_RS09250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC13_RS09270	COG1164	Oligoendopeptidase f
FOC13_RS09275	COG0516	GMP reductase activity
FOC13_RS09295	COG1272	protein, Hemolysin III
FOC13_RS09300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC13_RS09320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC13_RS09325	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC13_RS09330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC13_RS09335	COG2814	Major facilitator Superfamily
FOC13_RS09340	COG3275	phosphorelay sensor kinase activity
FOC13_RS09345	COG3279	Response regulator of the LytR AlgR family
FOC13_RS09360	COG0628	permease
FOC13_RS09365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC13_RS09365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC13_RS09370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC13_RS09375	COG1309	transcriptional regulator
FOC13_RS09380	COG0463	Glycosyl transferase, family 2
FOC13_RS09400	COG0488	(ABC) transporter
FOC13_RS09415	COG1607	acyl-coa hydrolase
FOC13_RS09425	COG0840	transmembrane signaling receptor activity
FOC13_RS09450	COG0477	Major facilitator Superfamily
FOC13_RS09455	COG3279	Response regulator of the LytR AlgR family
FOC13_RS09460	COG1966	Carbon starvation protein
FOC13_RS09465	COG2879	small protein
FOC13_RS09470	COG3706	GGDEF domain
FOC13_RS09475	COG0351	phosphomethylpyrimidine kinase
FOC13_RS09485	COG2197	response regulator
FOC13_RS09495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC13_RS09500	COG1011	Hydrolase
FOC13_RS09520	COG0460	homoserine dehydrogenase
FOC13_RS09530	COG1609	Transcriptional regulator
FOC13_RS09535	COG2755	lipolytic protein G-D-S-L family
FOC13_RS09540	COG1131	(ABC) transporter
FOC13_RS09545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC13_RS09555	COG2814	Major facilitator Superfamily
FOC13_RS09560	COG0561	phosphatase activity
FOC13_RS09565	COG2233	PERMEase
FOC13_RS09580	COG2363	Small membrane protein
FOC13_RS09590	COG3773	Cell wall hydrolase
FOC13_RS09605	COG0280	phosphate acetyltransferase
FOC13_RS09610	COG0095	Lipoate-protein ligase
FOC13_RS09635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS09640	COG1120	ATPase activity
FOC13_RS09645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS09650	COG1078	dGTPase activity
FOC13_RS09660	COG1994	Peptidase M50
FOC13_RS09670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC13_RS09675	COG0584	glycerophosphoryl diester phosphodiesterase
FOC13_RS09680	COG0789	Transcriptional regulator
FOC13_RS09685	COG2814	Major facilitator Superfamily
FOC13_RS09690	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC13_RS09695	COG0010	Belongs to the arginase family
FOC13_RS09710	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC13_RS09715	COG4506	Protein conserved in bacteria
FOC13_RS09720	COG0018	arginyl-trna synthetase
FOC13_RS09725	COG1595	DNA-templated transcription, initiation
FOC13_RS09745	COG2234	aminopeptidase activity
FOC13_RS09755	COG0024	Methionine aminopeptidase
FOC13_RS09760	COG1131	(ABC) transporter
FOC13_RS09765	COG0842	Transport permease protein
FOC13_RS09770	COG4585	Histidine kinase
FOC13_RS09775	COG2197	response regulator
FOC13_RS09800	COG3300	MHYT domain
FOC13_RS09800	COG5001	Diguanylate cyclase
FOC13_RS09810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC13_RS09815	COG2181	nitrate reductase activity
FOC13_RS09815	COG0247	lactate metabolic process
FOC13_RS09820	COG0183	Belongs to the thiolase family
FOC13_RS09825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC13_RS09830	COG1960	acyl-CoA dehydrogenase activity
FOC13_RS09835	COG1960	acyl-CoA dehydrogenase activity
FOC13_RS09845	COG3343	RNA polymerase activity
FOC13_RS09855	COG4821	SIS domain
FOC13_RS09870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC13_RS09875	COG1494	fructose-1,6-bisphosphatase
FOC13_RS09880	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC13_RS09895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC13_RS09900	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC13_RS09915	COG0009	L-threonylcarbamoyladenylate synthase
FOC13_RS09930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC13_RS09935	COG2259	Doxx family
FOC13_RS09940	COG2190	(PTS) system
FOC13_RS09950	COG0698	ribose 5-phosphate isomerase
FOC13_RS09985	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC13_RS10035	COG5001	Diguanylate cyclase
FOC13_RS10035	COG3300	MHYT domain
FOC13_RS10040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC13_RS10050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC13_RS10055	COG0649	NAD binding
FOC13_RS10070	COG0839	Belongs to the complex I subunit 6 family
FOC13_RS10080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC13_RS10085	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC13_RS10090	COG1007	ATP synthesis coupled electron transport
FOC13_RS10095	COG4836	Membrane
FOC13_RS10105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC13_RS10110	COG2385	sporulation resulting in formation of a cellular spore
FOC13_RS10115	COG4555	ABC transporter
FOC13_RS10120	COG3279	Response regulator of the LytR AlgR family
FOC13_RS10135	COG0739	heme binding
FOC13_RS10150	COG1609	Transcriptional regulator
FOC13_RS10195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC13_RS10200	COG1682	transport, permease protein
FOC13_RS10205	COG1134	teichoic acid transport
FOC13_RS10210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC13_RS10225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC13_RS10230	COG0745	RESPONSE REGULATOR receiver
FOC13_RS10235	COG5002	protein histidine kinase activity
FOC13_RS10270	COG1136	(ABC) transporter
FOC13_RS10275	COG0577	efflux transmembrane transporter activity
FOC13_RS10285	COG1191	sigma factor activity
FOC13_RS10315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC13_RS10320	COG4715	Zinc finger, swim domain protein
FOC13_RS10345	COG1388	LysM domain
FOC13_RS10345	COG3584	3D domain protein
FOC13_RS10350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC13_RS10365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS10380	COG1368	sulfuric ester hydrolase activity
FOC13_RS10390	COG2389	metal-binding protein
FOC13_RS10400	COG1620	l-lactate permease
FOC13_RS10410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC13_RS10415	COG1294	oxidase, subunit
FOC13_RS10420	COG1271	oxidase subunit
FOC13_RS10435	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC13_RS10440	COG0583	DNA-binding transcription factor activity
FOC13_RS10445	COG1511	domain protein
FOC13_RS10450	COG0346	lactoylglutathione lyase activity
FOC13_RS10460	COG1301	dicarboxylic acid transport
FOC13_RS10465	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC13_RS10475	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC13_RS10480	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC13_RS10485	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC13_RS10495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC13_RS10500	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC13_RS10505	COG1486	melibiose metabolic process
FOC13_RS10510	COG3394	polysaccharide catabolic process
FOC13_RS10525	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC13_RS10525	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC13_RS10535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC13_RS10540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC13_RS10545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC13_RS10550	COG1316	TRANSCRIPTIONal
FOC13_RS10555	COG1739	Uncharacterized protein family UPF0029
FOC13_RS10560	COG1307	EDD domain protein, DegV family
FOC13_RS10565	COG1733	regulation of RNA biosynthetic process
FOC13_RS10570	COG1388	LysM domain
FOC13_RS10570	COG0791	NLP P60 protein
FOC13_RS10575	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC13_RS10580	COG1040	competence protein
FOC13_RS10585	COG1278	Cold shock
FOC13_RS10590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC13_RS10595	COG0653	protein targeting
FOC13_RS10615	COG2884	Cell division ATP-binding protein ftsE
FOC13_RS10620	COG2177	Part of the ABC transporter FtsEX involved in
FOC13_RS10625	COG0793	Belongs to the peptidase S41A family
FOC13_RS10625	COG3409	Peptidoglycan-binding domain 1 protein
FOC13_RS10630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC13_RS10635	COG1132	(ABC) transporter
FOC13_RS10650	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC13_RS10660	COG0583	DNA-binding transcription factor activity
FOC13_RS10665	COG2855	membrane
FOC13_RS10690	COG0789	Transcriptional regulator
FOC13_RS10710	COG0556	nucleotide-excision repair
FOC13_RS10715	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC13_RS10725	COG1950	PFAM Membrane protein of
FOC13_RS10745	COG0110	maltose O-acetyltransferase activity
FOC13_RS10750	COG0457	Tetratricopeptide repeat
FOC13_RS10755	COG0492	ferredoxin-NADP+ reductase activity
FOC13_RS10765	COG1051	belongs to the nudix hydrolase family
FOC13_RS10775	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC13_RS10785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC13_RS10790	COG0740	serine-type endopeptidase activity
FOC13_RS10795	COG2323	membrane
FOC13_RS10810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC13_RS10835	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC13_RS10850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC13_RS10860	COG0149	triose-phosphate isomerase activity
FOC13_RS10865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC13_RS10875	COG4974	Belongs to the 'phage' integrase family
FOC13_RS10900	COG4695	Portal protein
FOC13_RS10995	COG1346	cytolysis
FOC13_RS11000	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC13_RS11005	COG1647	Serine aminopeptidase, S33
FOC13_RS11010	COG0557	exoribonuclease II activity
FOC13_RS11060	COG3223	Belongs to the PsiE family
FOC13_RS11065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS11080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC13_RS11085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC13_RS11095	COG0840	transmembrane signaling receptor activity
FOC13_RS11095	COG3290	protein histidine kinase activity
FOC13_RS11105	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC13_RS11110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC13_RS11115	COG1252	NADH dehydrogenase
FOC13_RS11125	COG1733	regulation of RNA biosynthetic process
FOC13_RS11130	COG2814	Major facilitator Superfamily
FOC13_RS11135	COG0656	L-ascorbic acid biosynthetic process
FOC13_RS11150	COG2910	NAD(P)H-binding
FOC13_RS11155	COG1115	amino acid carrier protein
FOC13_RS11160	COG1115	amino acid carrier protein
FOC13_RS11165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS11170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS11190	COG1611	Belongs to the LOG family
FOC13_RS11205	COG0783	Belongs to the Dps family
FOC13_RS11210	COG1115	amino acid carrier protein
FOC13_RS11215	COG0490	domain, Protein
FOC13_RS11220	COG0475	glutathione-regulated potassium exporter activity
FOC13_RS11235	COG1741	Belongs to the pirin family
FOC13_RS11240	COG3227	Zinc metalloprotease (Elastase)
FOC13_RS11245	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC13_RS11260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC13_RS11270	COG5002	protein histidine kinase activity
FOC13_RS11275	COG0745	RESPONSE REGULATOR receiver
FOC13_RS11280	COG1376	ErfK ybiS ycfS ynhG family protein
FOC13_RS11290	COG0586	Pfam SNARE associated Golgi protein
FOC13_RS11325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS11335	COG0706	membrane insertase activity
FOC13_RS11345	COG0531	amino acid
FOC13_RS11350	COG2814	Major facilitator Superfamily
FOC13_RS11365	COG0840	transmembrane signaling receptor activity
FOC13_RS11370	COG0011	TIGRFAM Protein of
FOC13_RS11385	COG1686	Belongs to the peptidase S11 family
FOC13_RS11395	COG1024	Enoyl-CoA hydratase
FOC13_RS11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC13_RS11400	COG0183	Belongs to the thiolase family
FOC13_RS11405	COG1960	acyl-CoA dehydrogenase activity
FOC13_RS11410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS11415	COG1309	transcriptional regulator
FOC13_RS11435	COG0039	L-malate dehydrogenase activity
FOC13_RS11480	COG1393	Belongs to the ArsC family
FOC13_RS11495	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC13_RS11500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC13_RS11510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC13_RS11515	COG2011	ABC-type metal ion transport system permease component
FOC13_RS11520	COG1464	Belongs to the NlpA lipoprotein family
FOC13_RS11525	COG1464	Belongs to the NlpA lipoprotein family
FOC13_RS11530	COG0396	ATPase activity
FOC13_RS11535	COG0719	Fe-S assembly protein
FOC13_RS11540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC13_RS11545	COG0822	iron-sulfur transferase activity
FOC13_RS11550	COG0719	Fe-S assembly protein
FOC13_RS11560	COG1695	Transcriptional regulator
FOC13_RS11565	COG0737	Belongs to the 5'-nucleotidase family
FOC13_RS11570	COG3377	Domain of unknown function (DUF1805)
FOC13_RS11580	COG0739	heme binding
FOC13_RS11605	COG4377	Putative membrane peptidase family (DUF2324)
FOC13_RS11610	COG0789	Transcriptional regulator
FOC13_RS11620	COG4470	Protein conserved in bacteria
FOC13_RS11635	COG1494	fructose-1,6-bisphosphatase
FOC13_RS11640	COG2445	Protein of unknown function DUF86
FOC13_RS11650	COG0647	UMP catabolic process
FOC13_RS11655	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC13_RS11665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC13_RS11670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC13_RS11680	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC13_RS11685	COG4837	Protein of unknown function (DUF1462)
FOC13_RS11725	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC13_RS11730	COG0390	transport system, permease component
FOC13_RS11745	COG1252	NADH dehydrogenase
FOC13_RS11760	COG0316	Belongs to the HesB IscA family
FOC13_RS11780	COG1683	Conserved Protein
FOC13_RS11795	COG3708	Transcriptional regulator
FOC13_RS11810	COG1252	NADH dehydrogenase
FOC13_RS11825	COG3584	3D domain protein
FOC13_RS11840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC13_RS11845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC13_RS11855	COG1268	BioY protein
FOC13_RS11865	COG2050	protein possibly involved in aromatic compounds catabolism
FOC13_RS11870	COG0423	glycine-tRNA ligase activity
FOC13_RS11885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC13_RS11890	COG5018	Exonuclease
FOC13_RS11905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC13_RS11915	COG2267	carboxylic ester hydrolase activity
FOC13_RS11920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC13_RS11925	COG1522	sequence-specific DNA binding
FOC13_RS11930	COG0436	Aminotransferase
FOC13_RS11935	COG1098	S1 RNA binding domain
FOC13_RS11940	COG2155	Conserved Protein
FOC13_RS11945	COG0166	Belongs to the GPI family
FOC13_RS11955	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC13_RS11960	COG1285	pathogenesis
FOC13_RS11995	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC13_RS12090	COG0039	L-malate dehydrogenase activity
FOC13_RS12110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC13_RS12115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC13_RS12120	COG0297	glycogen (starch) synthase activity
FOC13_RS12125	COG0058	SHG alpha-glucan phosphorylase activity
FOC13_RS12140	COG1278	Cold shock
FOC13_RS12145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC13_RS12150	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC13_RS12155	COG1169	isochorismate synthase
FOC13_RS12160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC13_RS12165	COG0596	Alpha beta hydrolase
FOC13_RS12170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC13_RS12180	COG4948	Mandelate Racemase Muconate Lactonizing
FOC13_RS12210	COG3964	amidohydrolase
FOC13_RS12250	COG1136	(ABC) transporter
FOC13_RS12255	COG0577	efflux transmembrane transporter activity
FOC13_RS12265	COG2205	protein histidine kinase activity
FOC13_RS12270	COG0745	RESPONSE REGULATOR receiver
FOC13_RS12275	COG2207	Transcriptional regulator
FOC13_RS12275	COG3708	Transcriptional regulator
FOC13_RS12280	COG1136	(ABC) transporter
FOC13_RS12285	COG0577	efflux transmembrane transporter activity
FOC13_RS12295	COG0586	Pfam SNARE associated Golgi protein
FOC13_RS12330	COG1597	lipid kinase activity
FOC13_RS12360	COG0745	RESPONSE REGULATOR receiver
FOC13_RS12365	COG5002	protein histidine kinase activity
FOC13_RS12400	COG1842	Phage shock protein A
FOC13_RS12425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS12445	COG1294	oxidase, subunit
FOC13_RS12450	COG1271	oxidase subunit
FOC13_RS12455	COG0288	reversible hydration of carbon dioxide
FOC13_RS12485	COG0494	nUDIX hydrolase
FOC13_RS12510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC13_RS12515	COG1116	anion transmembrane transporter activity
FOC13_RS12520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC13_RS12540	COG2267	carboxylic ester hydrolase activity
FOC13_RS12545	COG4191	Histidine kinase
FOC13_RS12550	COG5002	protein histidine kinase activity
FOC13_RS12555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC13_RS12605	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC13_RS12615	COG0438	transferase activity, transferring glycosyl groups
FOC13_RS12620	COG0671	phosphoesterase, PA-phosphatase related
FOC13_RS12625	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC13_RS12630	COG2267	carboxylic ester hydrolase activity
FOC13_RS12650	COG1794	racemase activity, acting on amino acids and derivatives
FOC13_RS12660	COG1131	(ABC) transporter
FOC13_RS12665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC13_RS12670	COG1242	4 iron, 4 sulfur cluster binding
FOC13_RS12690	COG1136	(ABC) transporter
FOC13_RS12700	COG0582	viral genome integration into host DNA
FOC13_RS12705	COG0490	domain, Protein
FOC13_RS12710	COG0475	glutathione-regulated potassium exporter activity
FOC13_RS12715	COG2814	Major facilitator Superfamily
FOC13_RS12755	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC13_RS12765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC13_RS12790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC13_RS12800	COG0303	'Molybdopterin
FOC13_RS12805	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC13_RS12810	COG0314	molybdopterin synthase activity
FOC13_RS12825	COG4975	Glucose uptake
FOC13_RS12835	COG1329	Transcriptional regulator
FOC13_RS12855	COG3832	glyoxalase III activity
FOC13_RS12865	COG2814	Major facilitator Superfamily
FOC13_RS12870	COG2081	HI0933 family
FOC13_RS12875	COG2244	polysaccharide biosynthetic process
FOC13_RS12880	COG1187	pseudouridine synthase activity
FOC13_RS12885	COG1349	DNA-binding transcription factor activity
FOC13_RS12900	COG1523	belongs to the glycosyl hydrolase 13 family
FOC13_RS12905	COG0510	thiamine kinase activity
FOC13_RS12920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS12930	COG1363	Peptidase, m42
FOC13_RS12935	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC13_RS12940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC13_RS12945	COG4848	Belongs to the UPF0354 family
FOC13_RS12950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC13_RS12960	COG1674	ftsk spoiiie
FOC13_RS12975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS12995	COG2309	aminopeptidase activity
FOC13_RS13005	COG3118	belongs to the thioredoxin family
FOC13_RS13010	COG4851	CamS sex pheromone cAM373 precursor
FOC13_RS13015	COG1609	Transcriptional regulator
FOC13_RS13050	COG0666	response to abiotic stimulus
FOC13_RS13060	COG0745	RESPONSE REGULATOR receiver
FOC13_RS13070	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC13_RS13075	COG0517	IMP dehydrogenase activity
FOC13_RS13080	COG0454	-acetyltransferase
FOC13_RS13085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC13_RS13100	COG1595	DNA-templated transcription, initiation
FOC13_RS13110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC13_RS13130	COG0626	cystathionine gamma-synthase activity
FOC13_RS13135	COG1956	GAF domain-containing protein
FOC13_RS13145	COG0697	spore germination
FOC13_RS13150	COG0583	DNA-binding transcription factor activity
FOC13_RS13160	COG1104	cysteine desulfurase activity
FOC13_RS13175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC13_RS13185	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC13_RS13190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC13_RS13200	COG3874	Sporulation protein YtfJ
FOC13_RS13205	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC13_RS13210	COG0827	DNA restriction-modification system
FOC13_RS13215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC13_RS13235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS13275	COG0589	response to stress
FOC13_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS13295	COG1476	TRANSCRIPTIONal
FOC13_RS13305	COG0662	Cupin 2, conserved barrel domain protein
FOC13_RS13310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS13345	COG0006	proline dipeptidase activity
FOC13_RS13360	COG4109	DRTGG domain
FOC13_RS13380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC13_RS13395	COG0587	DNA-directed DNA polymerase activity
FOC13_RS13400	COG0281	malic enzyme
FOC13_RS13405	COG1725	Transcriptional regulator
FOC13_RS13430	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC13_RS13435	COG0628	permease
FOC13_RS13445	COG0372	Belongs to the citrate synthase family
FOC13_RS13450	COG0538	isocitrate dehydrogenase activity
FOC13_RS13465	COG0745	RESPONSE REGULATOR receiver
FOC13_RS13470	COG5002	protein histidine kinase activity
FOC13_RS13475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC13_RS13475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC13_RS13480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC13_RS13485	COG1971	Probably functions as a manganese efflux pump
FOC13_RS13490	COG0237	dephospho-CoA kinase activity
FOC13_RS13495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC13_RS13505	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC13_RS13515	COG3611	Membrane attachment protein
FOC13_RS13520	COG1484	DNA-dependent DNA replication
FOC13_RS13530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC13_RS13535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC13_RS13555	COG1363	Peptidase, m42
FOC13_RS13560	COG1309	transcriptional regulator
FOC13_RS13565	COG1566	PFAM secretion protein HlyD family protein
FOC13_RS13570	COG2814	Major facilitator Superfamily
FOC13_RS13595	COG1418	mRNA catabolic process
FOC13_RS13605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC13_RS13615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC13_RS13615	COG0072	phenylalanine-tRNA ligase activity
FOC13_RS13620	COG0017	Asparaginyl-tRNA synthetase
FOC13_RS13650	COG1286	toxin biosynthetic process
FOC13_RS13655	COG1796	DNA polymerase
FOC13_RS13655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC13_RS13665	COG1187	pseudouridine synthase activity
FOC13_RS13670	COG1114	Component of the transport system for branched-chain amino acids
FOC13_RS13675	COG5386	Cell surface protein
FOC13_RS13685	COG5386	Cell surface protein
FOC13_RS13700	COG1120	ATPase activity
FOC13_RS13705	COG4509	Sortase family
FOC13_RS13720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC13_RS13725	COG4895	conserved protein (DUF2196)
FOC13_RS13730	COG0745	RESPONSE REGULATOR receiver
FOC13_RS13735	COG2205	protein histidine kinase activity
FOC13_RS13740	COG1131	(ABC) transporter
FOC13_RS13765	COG2318	DinB family
FOC13_RS13785	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS13790	COG1309	transcriptional regulator
FOC13_RS13795	COG1024	Enoyl-CoA hydratase
FOC13_RS13800	COG2086	electron transfer activity
FOC13_RS13805	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC13_RS13810	COG3118	belongs to the thioredoxin family
FOC13_RS13820	COG1719	4-vinyl reductase, 4VR
FOC13_RS13825	COG2009	succinate dehydrogenase
FOC13_RS13830	COG1053	succinate dehydrogenase
FOC13_RS13835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC13_RS13840	COG0824	Thioesterase
FOC13_RS13845	COG1876	peptidase activity
FOC13_RS13850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC13_RS13860	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC13_RS13865	COG4152	abc transporter atp-binding protein
FOC13_RS13870	COG1668	transmembrane transport
FOC13_RS13875	COG1959	2 iron, 2 sulfur cluster binding
FOC13_RS13885	COG0697	spore germination
FOC13_RS13890	COG1396	sequence-specific DNA binding
FOC13_RS13895	COG1983	PspC domain protein
FOC13_RS13910	COG3279	Response regulator of the LytR AlgR family
FOC13_RS13920	COG4608	Belongs to the ABC transporter superfamily
FOC13_RS13925	COG0444	Belongs to the ABC transporter superfamily
FOC13_RS13945	COG0402	S-adenosylhomocysteine deaminase activity
FOC13_RS13950	COG0402	S-adenosylhomocysteine deaminase activity
FOC13_RS13960	COG2233	PERMEase
FOC13_RS13965	COG2197	response regulator
FOC13_RS13980	COG1309	transcriptional regulator
FOC13_RS14000	COG5401	PFAM Sporulation and spore germination
FOC13_RS14010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC13_RS14015	COG0622	Phosphoesterase
FOC13_RS14060	COG0470	DNA polymerase III
FOC13_RS14060	COG1067	ATP-dependent peptidase activity
FOC13_RS14075	COG1764	response to oxidative stress
FOC13_RS14080	COG1846	Transcriptional regulator
FOC13_RS14090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC13_RS14100	COG1587	Uroporphyrinogen-III synthase
FOC13_RS14105	COG0113	porphobilinogen synthase activity
FOC13_RS14115	COG1388	LysM domain
FOC13_RS14125	COG0525	valine-tRNA ligase activity
FOC13_RS14130	COG0285	dihydrofolate synthase activity
FOC13_RS14150	COG1077	Cell shape determining protein MreB Mrl
FOC13_RS14155	COG1792	Involved in formation and maintenance of cell shape
FOC13_RS14170	COG2894	cell division
FOC13_RS14175	COG0739	heme binding
FOC13_RS14180	COG1994	Peptidase M50
FOC13_RS14185	COG1530	ribonuclease E activity
FOC13_RS14195	COG2868	ribosomal protein
FOC13_RS14210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC13_RS14215	COG0745	RESPONSE REGULATOR receiver
FOC13_RS14225	COG1136	(ABC) transporter
FOC13_RS14230	COG0577	efflux transmembrane transporter activity
FOC13_RS14235	COG0577	efflux transmembrane transporter activity
FOC13_RS14240	COG0077	Prephenate dehydratase
FOC13_RS14245	COG2258	MOSC domain
FOC13_RS14250	COG1827	regulation of RNA biosynthetic process
FOC13_RS14255	COG1104	cysteine desulfurase activity
FOC13_RS14260	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC13_RS14265	COG0157	Belongs to the NadC ModD family
FOC13_RS14290	COG0640	Transcriptional regulator
FOC13_RS14295	COG0697	spore germination
FOC13_RS14300	COG0697	spore germination
FOC13_RS14310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC13_RS14340	COG1862	Preprotein translocase
FOC13_RS14350	COG2323	membrane
FOC13_RS14355	COG2244	polysaccharide biosynthetic process
FOC13_RS14365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC13_RS14365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC13_RS14370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC13_RS14375	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC13_RS14375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC13_RS14385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC13_RS14395	COG0124	histidyl-tRNA synthetase
FOC13_RS14405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC13_RS14415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC13_RS14420	COG1959	2 iron, 2 sulfur cluster binding
FOC13_RS14425	COG1104	cysteine desulfurase activity
FOC13_RS14430	COG0482	sulfurtransferase activity
FOC13_RS14440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC13_RS14460	COG0628	permease
FOC13_RS14470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC13_RS14490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC13_RS14520	COG0768	penicillin binding
FOC13_RS14545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC13_RS14550	COG0626	cystathionine gamma-synthase activity
FOC13_RS14555	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS14555	COG1454	alcohol dehydrogenase
FOC13_RS14565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS14605	COG2259	Doxx family
FOC13_RS14620	COG3186	Phenylalanine-4-hydroxylase
FOC13_RS14625	COG1404	Belongs to the peptidase S8 family
FOC13_RS14660	COG2267	carboxylic ester hydrolase activity
FOC13_RS14670	COG1785	Belongs to the alkaline phosphatase family
FOC13_RS14680	COG2357	RelA SpoT domain protein
FOC13_RS14685	COG0778	Nitroreductase
FOC13_RS14695	COG1595	DNA-templated transcription, initiation
FOC13_RS14705	COG1191	sigma factor activity
FOC13_RS14720	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC13_RS14725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC13_RS14735	COG1534	Rna-binding protein
FOC13_RS14745	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC13_RS14750	COG0799	negative regulation of ribosome biogenesis
FOC13_RS14755	COG2226	methyltransferase
FOC13_RS14760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC13_RS14765	COG1596	polysaccharide export
FOC13_RS14765	COG1555	photosystem II stabilization
FOC13_RS14770	COG2131	deaminase
FOC13_RS14775	COG2333	competence protein COMEC
FOC13_RS14775	COG0658	competence protein
FOC13_RS14785	COG1466	dna polymerase III delta subunit
FOC13_RS14810	COG1733	regulation of RNA biosynthetic process
FOC13_RS14815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC13_RS14825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC13_RS14845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC13_RS14850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC13_RS14860	COG1610	YqeY-like protein
FOC13_RS14875	COG1702	phosphate starvation-inducible protein PhoH
FOC13_RS14880	COG1480	7TM receptor with intracellular HD hydrolase
FOC13_RS14890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC13_RS14895	COG0295	cytidine deaminase activity
FOC13_RS14900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC13_RS14915	COG0517	IMP dehydrogenase activity
FOC13_RS14925	COG0358	DNA primase activity
FOC13_RS14930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC13_RS14935	COG2010	Cytochrome c
FOC13_RS14940	COG2384	SAM-dependent methyltransferase
FOC13_RS14945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC13_RS14975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS14980	COG1121	(ABC) transporter
FOC13_RS14985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC13_RS14990	COG0735	belongs to the Fur family
FOC13_RS15015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC13_RS15020	COG0477	Major facilitator Superfamily
FOC13_RS15030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC13_RS15035	COG0573	inorganic phosphate transmembrane transporter activity
FOC13_RS15040	COG0581	inorganic phosphate transmembrane transporter activity
FOC13_RS15045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC13_RS15050	COG0704	Plays a role in the regulation of phosphate uptake
FOC13_RS15055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC13_RS15065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC13_RS15070	COG4483	Protein conserved in bacteria
FOC13_RS15075	COG1940	carbohydrate kinase activity
FOC13_RS15085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS15105	COG0626	cystathionine gamma-synthase activity
FOC13_RS15110	COG0626	cystathionine gamma-synthase activity
FOC13_RS15115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC13_RS15115	COG0646	methionine synthase
FOC13_RS15120	COG0646	methionine synthase
FOC13_RS15120	COG1410	methionine synthase
FOC13_RS15125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC13_RS15175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC13_RS15180	COG1459	type II secretion system
FOC13_RS15190	COG4970	Tfp pilus assembly protein FimT
FOC13_RS15245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC13_RS15275	COG1725	Transcriptional regulator
FOC13_RS15280	COG1131	(ABC) transporter
FOC13_RS15315	COG2076	Multidrug Resistance protein
FOC13_RS15320	COG2076	Multidrug Resistance protein
FOC13_RS15330	COG1609	Transcriptional regulator
FOC13_RS15335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC13_RS15340	COG0095	Lipoate-protein ligase
FOC13_RS15360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC13_RS15370	COG3872	metal-dependent enzyme
FOC13_RS15385	COG0006	proline dipeptidase activity
FOC13_RS15410	COG3854	ATPases associated with a variety of cellular activities
FOC13_RS15455	COG0511	ligase activity, forming carbon-carbon bonds
FOC13_RS15460	COG0439	Biotin carboxylase
FOC13_RS15465	COG1302	Protein conserved in bacteria
FOC13_RS15490	COG0142	geranyltranstransferase activity
FOC13_RS15500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC13_RS15510	COG0497	DNA recombination
FOC13_RS15515	COG0750	zinc metalloprotease
FOC13_RS15520	COG0745	RESPONSE REGULATOR receiver
FOC13_RS15530	COG3093	addiction module antidote protein HigA
FOC13_RS15535	COG0584	glycerophosphoryl diester phosphodiesterase
FOC13_RS15545	COG3829	transcription factor binding
FOC13_RS15545	COG3290	protein histidine kinase activity
FOC13_RS15550	COG0280	phosphate acetyltransferase
FOC13_RS15555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC13_RS15565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC13_RS15570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC13_RS15575	COG0022	dehydrogenase e1 component
FOC13_RS15580	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC13_RS15585	COG0772	Belongs to the SEDS family
FOC13_RS15605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC13_RS15610	COG0765	amino acid transport
FOC13_RS15615	COG1126	abc transporter atp-binding protein
FOC13_RS15620	COG4129	membrane
FOC13_RS15625	COG1376	ErfK ybiS ycfS ynhG family protein
FOC13_RS15640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS15645	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC13_RS15655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC13_RS15675	COG1760	l-serine dehydratase
FOC13_RS15680	COG1760	l-serine dehydratase
FOC13_RS15685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC13_RS15695	COG0300	oxidoreductase activity
FOC13_RS15710	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC13_RS15720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC13_RS15740	COG1522	sequence-specific DNA binding
FOC13_RS15750	COG0737	Belongs to the 5'-nucleotidase family
FOC13_RS15765	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC13_RS15775	COG0156	8-amino-7-oxononanoate synthase activity
FOC13_RS15780	COG2226	methyltransferase
FOC13_RS15780	COG1073	alpha beta
FOC13_RS15785	COG4106	trans-aconitate 2-methyltransferase activity
FOC13_RS15790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC13_RS15810	COG0307	riboflavin synthase, alpha
FOC13_RS15815	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC13_RS15815	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC13_RS15830	COG1073	alpha beta
FOC13_RS15835	COG0456	acetyltransferase
FOC13_RS15840	COG1609	Transcriptional regulator
FOC13_RS15845	COG2056	Na+-H+ antiporter family
FOC13_RS15850	COG0596	Alpha beta hydrolase
FOC13_RS15860	COG0737	Belongs to the 5'-nucleotidase family
FOC13_RS15860	COG4085	toxin activity
FOC13_RS15860	COG1525	nuclease
FOC13_RS15870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC13_RS15870	COG0456	acetyltransferase
FOC13_RS15875	COG0656	L-ascorbic acid biosynthetic process
FOC13_RS15880	COG0667	Aldo Keto reductase
FOC13_RS15900	COG1300	Membrane
FOC13_RS15905	COG0735	belongs to the Fur family
FOC13_RS15915	COG4974	Belongs to the 'phage' integrase family
FOC13_RS15940	COG0598	Magnesium transport protein CorA
FOC13_RS15955	COG1846	Transcriptional regulator
FOC13_RS15970	COG1131	(ABC) transporter
FOC13_RS15975	COG1725	Transcriptional regulator
FOC13_RS15980	COG1686	Belongs to the peptidase S11 family
FOC13_RS16000	COG0733	neurotransmitter:sodium symporter activity
FOC13_RS16025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC13_RS16040	COG0697	spore germination
FOC13_RS16045	COG0561	phosphatase activity
FOC13_RS16050	COG4086	secreted protein
FOC13_RS16055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC13_RS16060	COG0456	acetyltransferase
FOC13_RS16065	COG1547	Domain of unknown function (DUF309)
FOC13_RS16090	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC13_RS16110	COG3711	transcriptional antiterminator
FOC13_RS16115	COG1263	PTS System
FOC13_RS16115	COG2190	(PTS) system
FOC13_RS16115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC13_RS16140	COG0778	Nitroreductase
FOC13_RS16145	COG3706	GGDEF domain
FOC13_RS16165	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC13_RS16185	COG0436	Aminotransferase
FOC13_RS16190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC13_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS16215	COG1695	Transcriptional regulator
FOC13_RS16255	COG0183	Belongs to the thiolase family
FOC13_RS16295	COG3842	ATPase activity
FOC13_RS16300	COG0366	Alpha amylase catalytic
FOC13_RS16310	COG2182	Extracellular solute-binding protein
FOC13_RS16315	COG1175	transmembrane transport
FOC13_RS16320	COG3833	ABC-type maltose transport systems, permease component
FOC13_RS16325	COG1609	Transcriptional regulator
FOC13_RS16330	COG0436	Aminotransferase
FOC13_RS16340	COG2205	protein histidine kinase activity
FOC13_RS16350	COG3209	COG3209 Rhs family protein
FOC13_RS16370	COG2814	Major facilitator Superfamily
FOC13_RS16405	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC13_RS16415	COG1408	metallophosphoesterase
FOC13_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS16425	COG2200	EAL domain
FOC13_RS16440	COG4703	Protein of unknown function (DUF1797)
FOC13_RS16445	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC13_RS16455	COG0517	IMP dehydrogenase activity
FOC13_RS16460	COG0583	DNA-binding transcription factor activity
FOC13_RS16480	COG0569	domain protein
FOC13_RS16485	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC13_RS16500	COG0242	peptide deformylase activity
FOC13_RS16510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC13_RS16515	COG0022	dehydrogenase e1 component
FOC13_RS16520	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC13_RS16565	COG1982	Orn Lys Arg decarboxylase major
FOC13_RS16585	COG0483	inositol monophosphate 1-phosphatase activity
FOC13_RS16610	COG4896	Protein conserved in bacteria
FOC13_RS16620	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC13_RS16625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC13_RS16630	COG4838	Belongs to the UPF0358 family
FOC13_RS16635	COG0772	Belongs to the SEDS family
FOC13_RS16640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC13_RS16675	COG3336	cytochrome c oxidase
FOC13_RS16690	COG2340	Cysteine-rich secretory protein family
FOC13_RS16705	COG0406	alpha-ribazole phosphatase activity
FOC13_RS16710	COG3679	Belongs to the UPF0342 family
FOC13_RS16725	COG0742	ribosomal rna small subunit methyltransferase
FOC13_RS16735	COG3314	Sporulation integral membrane protein YlbJ
FOC13_RS16740	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC13_RS16745	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC13_RS16755	COG0582	viral genome integration into host DNA
FOC13_RS16765	COG1396	sequence-specific DNA binding
FOC13_RS16775	COG1396	sequence-specific DNA binding
FOC13_RS16795	COG1484	DNA-dependent DNA replication
FOC13_RS16820	COG1191	sigma factor activity
FOC13_RS16895	COG0582	viral genome integration into host DNA
FOC13_RS16920	COG4626	Terminase
FOC13_RS16920	COG1802	Transcriptional regulator
FOC13_RS17010	COG4824	toxin secretion phage lysis holin
FOC13_RS17060	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC13_RS17085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC13_RS17100	COG4839	cell division protein FtsL
FOC13_RS17110	COG0768	penicillin binding
FOC13_RS17115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC13_RS17130	COG0772	Belongs to the SEDS family
FOC13_RS17135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC13_RS17140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC13_RS17145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC13_RS17150	COG0849	cell division
FOC13_RS17155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC13_RS17165	COG1191	sigma factor activity
FOC13_RS17170	COG1191	sigma factor activity
FOC13_RS17175	COG1873	PFAM PRC-barrel domain
FOC13_RS17185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC13_RS17195	COG0762	integral membrane protein
FOC13_RS17200	COG2302	S4 RNA-binding domain
FOC13_RS17205	COG3599	regulation of cell shape
FOC13_RS17225	COG0564	pseudouridine synthase activity
FOC13_RS17250	COG0505	Belongs to the CarA family
FOC13_RS17290	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC13_RS17305	COG0006	proline dipeptidase activity
FOC13_RS17315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC13_RS17320	COG1561	YicC-like family, N-terminal region
FOC13_RS17330	COG0194	GDP metabolic process
FOC13_RS17340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC13_RS17345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC13_RS17350	COG0242	peptide deformylase activity
FOC13_RS17360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC13_RS17360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC13_RS17370	COG0631	protein serine/threonine phosphatase activity
FOC13_RS17375	COG0515	serine threonine protein kinase
FOC13_RS17375	COG2815	serine threonine protein kinase
FOC13_RS17380	COG1162	GTPase activity
FOC13_RS17385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC13_RS17390	COG1564	THIamine pyrophosphokinase
FOC13_RS17405	COG1302	Protein conserved in bacteria
FOC13_RS17410	COG1461	Dihydroxyacetone kinase
FOC13_RS17415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC13_RS17430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC13_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS17450	COG1196	nuclear chromosome segregation
FOC13_RS17455	COG0552	protein localization to endoplasmic reticulum
FOC13_RS17465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC13_RS17475	COG1837	Belongs to the UPF0109 family
FOC13_RS17515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC13_RS17525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC13_RS17535	COG4974	Belongs to the 'phage' integrase family
FOC13_RS17565	COG0528	UMP kinase activity
FOC13_RS17575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC13_RS17580	COG4589	Belongs to the CDS family
FOC13_RS17585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC13_RS17590	COG0750	zinc metalloprotease
FOC13_RS17610	COG0195	Participates in both transcription termination and antitermination
FOC13_RS17615	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC13_RS17620	COG1358	cellular component organization or biogenesis
FOC13_RS17630	COG1550	Protein conserved in bacteria
FOC13_RS17640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC13_RS17645	COG0196	riboflavin kinase activity
FOC13_RS17660	COG0726	polysaccharide deacetylase
FOC13_RS17665	COG0612	Peptidase, M16
FOC13_RS17670	COG1873	PFAM PRC-barrel domain
FOC13_RS17675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC13_RS17680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC13_RS17685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC13_RS17690	COG0527	aspartate kinase activity
FOC13_RS17700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC13_RS17705	COG0740	serine-type endopeptidase activity
FOC13_RS17715	COG1674	ftsk spoiiie
FOC13_RS17720	COG2188	Transcriptional regulator
FOC13_RS17745	COG0612	Peptidase, M16
FOC13_RS17750	COG0612	Peptidase, M16
FOC13_RS17755	COG0300	oxidoreductase activity
FOC13_RS17770	COG1426	Protein conserved in bacteria
FOC13_RS17775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC13_RS17800	COG1692	metallophosphoesterase
FOC13_RS17805	COG2359	stage V sporulation protein S
FOC13_RS17815	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC13_RS17815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC13_RS17820	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC13_RS17825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC13_RS17830	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC13_RS17875	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC13_RS17885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC13_RS17890	COG1368	sulfuric ester hydrolase activity
FOC13_RS17895	COG0562	UDP-galactopyranose mutase
FOC13_RS17900	COG3773	Cell wall hydrolase
FOC13_RS17905	COG1404	Belongs to the peptidase S8 family
FOC13_RS17925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC13_RS17930	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC13_RS17930	COG0596	Alpha beta hydrolase
FOC13_RS17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS17940	COG1380	Effector of murein hydrolase LrgA
FOC13_RS17945	COG1346	cytolysis
FOC13_RS17965	COG3300	MHYT domain
FOC13_RS17965	COG5001	Diguanylate cyclase
FOC13_RS17970	COG0346	lactoylglutathione lyase activity
FOC13_RS17975	COG2267	carboxylic ester hydrolase activity
FOC13_RS17990	COG2364	Membrane
FOC13_RS18000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC13_RS18005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC13_RS18010	COG2169	Transcriptional regulator
FOC13_RS18015	COG0708	Exodeoxyribonuclease III
FOC13_RS18025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS18030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS18035	COG1120	ATPase activity
FOC13_RS18040	COG2819	hydrolase of the alpha beta superfamily
FOC13_RS18050	COG1937	Protein conserved in bacteria
FOC13_RS18055	COG2608	mercury ion transmembrane transporter activity
FOC13_RS18060	COG2217	Heavy metal translocating P-type atpase
FOC13_RS18070	COG2116	formate transmembrane transporter activity
FOC13_RS18075	COG1408	metallophosphoesterase
FOC13_RS18085	COG1113	amino acid transport
FOC13_RS18095	COG2322	membrane
FOC13_RS18105	COG1349	DNA-binding transcription factor activity
FOC13_RS18110	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC13_RS18115	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC13_RS18115	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC13_RS18115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC13_RS18120	COG1388	LysM domain
FOC13_RS18120	COG3584	3D domain protein
FOC13_RS18150	COG0464	growth
FOC13_RS18160	COG2860	membrane
FOC13_RS18170	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC13_RS18175	COG0789	Transcriptional regulator
FOC13_RS18180	COG0174	glutamine synthetase
FOC13_RS18200	COG1396	sequence-specific DNA binding
FOC13_RS18280	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC13_RS18315	COG1595	DNA-templated transcription, initiation
FOC13_RS18460	COG4824	toxin secretion phage lysis holin
FOC13_RS18465	COG3409	Peptidoglycan-binding domain 1 protein
FOC13_RS18465	COG1388	LysM domain
FOC13_RS18465	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS18495	COG1695	Transcriptional regulator
FOC13_RS18515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC13_RS18535	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC13_RS18540	COG3639	organic phosphonate transmembrane transporter activity
FOC13_RS18570	COG1132	(ABC) transporter
FOC13_RS18575	COG1132	(ABC) transporter
FOC13_RS18590	COG3409	Peptidoglycan-binding domain 1 protein
FOC13_RS18590	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS18615	COG1346	cytolysis
FOC13_RS18620	COG1380	Effector of murein hydrolase LrgA
FOC13_RS18625	COG0583	DNA-binding transcription factor activity
FOC13_RS18635	COG0785	Cytochrome C biogenesis protein
FOC13_RS18640	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC13_RS18690	COG2226	methyltransferase
FOC13_RS18715	COG0010	Belongs to the arginase family
FOC13_RS18720	COG1329	Transcriptional regulator
FOC13_RS18725	COG1902	pentaerythritol trinitrate reductase activity
FOC13_RS18730	COG0069	glutamate synthase activity
FOC13_RS18735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC13_RS18740	COG0346	lactoylglutathione lyase activity
FOC13_RS18745	COG0400	carboxylic ester hydrolase activity
FOC13_RS18750	COG5002	protein histidine kinase activity
FOC13_RS18760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS18810	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS18815	COG1268	BioY protein
FOC13_RS18820	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS18825	COG0183	Belongs to the thiolase family
FOC13_RS18840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC13_RS18870	COG0726	polysaccharide deacetylase
FOC13_RS18880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC13_RS18885	COG2274	protein secretion by the type I secretion system
FOC13_RS18895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC13_RS18925	COG0824	Thioesterase
FOC13_RS18930	COG4841	protein insertion into membrane
FOC13_RS18935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC13_RS18950	COG0745	RESPONSE REGULATOR receiver
FOC13_RS18955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC13_RS18960	COG1832	CoA-binding protein
FOC13_RS18965	COG0187	DNA topoisomerase II activity
FOC13_RS18970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC13_RS18975	COG0673	inositol 2-dehydrogenase activity
FOC13_RS18985	COG1131	(ABC) transporter
FOC13_RS19000	COG1595	DNA-templated transcription, initiation
FOC13_RS19010	COG1316	TRANSCRIPTIONal
FOC13_RS19020	COG4166	transmembrane transport
FOC13_RS19025	COG4166	transmembrane transport
FOC13_RS19030	COG4166	transmembrane transport
FOC13_RS19035	COG2226	methyltransferase
FOC13_RS19075	COG0697	spore germination
FOC13_RS19080	COG3383	formate dehydrogenase (NAD+) activity
FOC13_RS19085	COG2427	Protein of unknown function (DUF1641)
FOC13_RS19090	COG5609	conserved protein (DUF2294)
FOC13_RS19095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC13_RS19105	COG2116	formate transmembrane transporter activity
FOC13_RS19110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC13_RS19115	COG0303	'Molybdopterin
FOC13_RS19120	COG0314	molybdopterin synthase activity
FOC13_RS19130	COG0489	protein tyrosine kinase activity
FOC13_RS19145	COG3326	Membrane
FOC13_RS19150	COG2962	Rard protein
FOC13_RS19155	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC13_RS19160	COG1657	PFAM Prenyltransferase squalene oxidase
FOC13_RS19170	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS19175	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS19185	COG4145	pantothenate transmembrane transporter activity
FOC13_RS19200	COG0165	Argininosuccinate lyase
FOC13_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS19240	COG0716	FMN binding
FOC13_RS19250	COG1278	Cold shock
FOC13_RS19275	COG2720	vancomycin resistance protein
FOC13_RS19280	COG2514	catechol 2,3-dioxygenase activity
FOC13_RS19295	COG1285	pathogenesis
FOC13_RS19305	COG1024	Enoyl-CoA hydratase
FOC13_RS19310	COG1216	Glycosyl transferase, family 2
FOC13_RS19340	COG0277	FAD linked oxidase domain protein
FOC13_RS19345	COG0385	Bile acid
FOC13_RS19355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC13_RS19360	COG2808	Putative FMN-binding domain
FOC13_RS19380	COG0604	alcohol dehydrogenase
FOC13_RS19385	COG0640	Transcriptional regulator
FOC13_RS19410	COG0584	glycerophosphoryl diester phosphodiesterase
FOC13_RS19440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC13_RS19445	COG1164	Oligoendopeptidase f
FOC13_RS19465	COG1193	negative regulation of DNA recombination
FOC13_RS19485	COG0583	DNA-binding transcription factor activity
FOC13_RS19515	COG0384	phenazine biosynthesis protein PhzF
FOC13_RS19520	COG3739	integral membrane protein
FOC13_RS19525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS19530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC13_RS19535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS19555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC13_RS19560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC13_RS19590	COG2814	Major facilitator Superfamily
FOC13_RS19595	COG1113	amino acid transport
FOC13_RS19635	COG2072	flavoprotein involved in K transport
FOC13_RS19670	COG3409	Peptidoglycan-binding domain 1 protein
FOC13_RS19670	COG3757	hydrolase, family 25
FOC13_RS19675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS19685	COG1151	hydroxylamine reductase activity
FOC13_RS19710	COG3152	Membrane
FOC13_RS19730	COG1309	transcriptional regulator
FOC13_RS19745	COG1191	sigma factor activity
FOC13_RS19780	COG1733	regulation of RNA biosynthetic process
FOC13_RS19790	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS19800	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS19810	COG0384	phenazine biosynthesis protein PhzF
FOC13_RS19830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS19845	COG1733	regulation of RNA biosynthetic process
FOC13_RS19850	COG1733	regulation of RNA biosynthetic process
FOC13_RS19855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC13_RS19865	COG2188	Transcriptional regulator
FOC13_RS19870	COG1733	regulation of RNA biosynthetic process
FOC13_RS19875	COG1393	Belongs to the ArsC family
FOC13_RS19900	COG0814	amino acid
FOC13_RS19905	COG0346	lactoylglutathione lyase activity
FOC13_RS19920	COG2814	Major facilitator Superfamily
FOC13_RS19925	COG0656	L-ascorbic acid biosynthetic process
FOC13_RS19950	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS19965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC13_RS19970	COG0604	alcohol dehydrogenase
FOC13_RS19975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC13_RS19980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC13_RS19990	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC13_RS19995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC13_RS20005	COG1070	Carbohydrate kinase
FOC13_RS20010	COG2706	6-phosphogluconolactonase activity
FOC13_RS20015	COG3813	Protein conserved in bacteria
FOC13_RS20020	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC13_RS20025	COG0697	spore germination
FOC13_RS20030	COG0789	Transcriptional regulator
FOC13_RS20035	COG1253	flavin adenine dinucleotide binding
FOC13_RS20065	COG0477	Major facilitator Superfamily
FOC13_RS20075	COG2226	methyltransferase
FOC13_RS20090	COG0628	permease
FOC13_RS20095	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC13_RS20100	COG0180	Tryptophanyl-tRNA synthetase
FOC13_RS20105	COG1136	(ABC) transporter
FOC13_RS20115	COG0110	maltose O-acetyltransferase activity
FOC13_RS20120	COG0738	Major facilitator superfamily
FOC13_RS20125	COG1940	carbohydrate kinase activity
FOC13_RS20130	COG0346	lactoylglutathione lyase activity
FOC13_RS20165	COG1011	Hydrolase
FOC13_RS20190	COG1131	(ABC) transporter
FOC13_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS20220	COG0778	Nitroreductase
FOC13_RS20225	COG1733	regulation of RNA biosynthetic process
FOC13_RS20240	COG0124	histidyl-tRNA synthetase
FOC13_RS20245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC13_RS20250	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC13_RS20255	COG3620	sequence-specific DNA binding
FOC13_RS20270	COG2356	endonuclease I
FOC13_RS20275	COG1288	antiporter activity
FOC13_RS20280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC13_RS20295	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC13_RS20300	COG1122	ATPase activity
FOC13_RS20330	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC13_RS20340	COG2031	fatty acid transporter
FOC13_RS20350	COG1309	transcriptional regulator
FOC13_RS20355	COG2076	Multidrug Resistance protein
FOC13_RS20375	COG1131	(ABC) transporter
FOC13_RS20380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC13_RS20395	COG2814	Major facilitator Superfamily
FOC13_RS20400	COG1846	Transcriptional regulator
FOC13_RS20410	COG0477	Major facilitator Superfamily
FOC13_RS20460	COG2207	Transcriptional regulator
FOC13_RS20460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS20465	COG0662	Cupin 2, conserved barrel domain protein
FOC13_RS20480	COG1595	DNA-templated transcription, initiation
FOC13_RS20500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC13_RS20515	COG0531	amino acid
FOC13_RS20520	COG1522	sequence-specific DNA binding
FOC13_RS20525	COG1335	isochorismatase
FOC13_RS20535	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC13_RS20540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC13_RS20550	COG1760	l-serine dehydratase
FOC13_RS20555	COG1760	l-serine dehydratase
FOC13_RS20560	COG0814	amino acid
FOC13_RS20575	COG1309	transcriptional regulator
FOC13_RS20580	COG2814	Major facilitator Superfamily
FOC13_RS20600	COG0534	Mate efflux family protein
FOC13_RS20630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC13_RS20645	COG0457	Tetratricopeptide repeat
FOC13_RS20650	COG1609	Transcriptional regulator
FOC13_RS20660	COG0561	phosphatase activity
FOC13_RS20665	COG0673	inositol 2-dehydrogenase activity
FOC13_RS20670	COG0738	Major facilitator superfamily
FOC13_RS20690	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC13_RS20700	COG0583	DNA-binding transcription factor activity
FOC13_RS20710	COG1139	Iron-sulfur cluster binding protein
FOC13_RS20715	COG1556	Lactate utilization protein
FOC13_RS20720	COG2271	Major facilitator Superfamily
FOC13_RS20725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS20730	COG2808	Putative FMN-binding domain
FOC13_RS20740	COG1846	Transcriptional regulator
FOC13_RS20745	COG2364	Membrane
FOC13_RS20755	COG5002	protein histidine kinase activity
FOC13_RS20755	COG3850	Histidine kinase
FOC13_RS20770	COG0577	efflux transmembrane transporter activity
FOC13_RS20775	COG1136	(ABC) transporter
FOC13_RS20790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC13_RS20795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC13_RS20805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC13_RS20810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS20825	COG1476	TRANSCRIPTIONal
FOC13_RS20845	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC13_RS20870	COG3850	Histidine kinase
FOC13_RS20870	COG5002	protein histidine kinase activity
FOC13_RS20875	COG0745	RESPONSE REGULATOR receiver
FOC13_RS20900	COG2814	Major facilitator Superfamily
FOC13_RS20940	COG2169	Transcriptional regulator
FOC13_RS20965	COG0346	lactoylglutathione lyase activity
FOC13_RS20980	COG1522	sequence-specific DNA binding
FOC13_RS20995	COG0443	Heat shock 70 kDa protein
FOC13_RS21010	COG0640	Transcriptional regulator
FOC13_RS21015	COG0346	lactoylglutathione lyase activity
FOC13_RS21020	COG0798	PFAM Bile acid sodium symporter
FOC13_RS21050	COG1121	(ABC) transporter
FOC13_RS21055	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC13_RS21060	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC13_RS21065	COG2267	carboxylic ester hydrolase activity
FOC13_RS21070	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC13_RS21085	COG5609	conserved protein (DUF2294)
FOC13_RS21090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC13_RS21100	COG0288	reversible hydration of carbon dioxide
FOC13_RS21105	COG0415	Belongs to the DNA photolyase family
FOC13_RS21145	COG1846	Transcriptional regulator
FOC13_RS21150	COG0583	DNA-binding transcription factor activity
FOC13_RS21170	COG1335	isochorismatase
FOC13_RS21175	COG2267	carboxylic ester hydrolase activity
FOC13_RS21180	COG0753	catalase activity
FOC13_RS21185	COG0737	Belongs to the 5'-nucleotidase family
FOC13_RS21220	COG2066	Belongs to the glutaminase family
FOC13_RS21230	COG0784	Response regulator, receiver
FOC13_RS21255	COG0281	malic enzyme
FOC13_RS21265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC13_RS21270	COG1114	Component of the transport system for branched-chain amino acids
FOC13_RS21275	COG0531	amino acid
FOC13_RS21280	COG0322	excinuclease ABC activity
FOC13_RS21290	COG1396	sequence-specific DNA binding
FOC13_RS21295	COG0252	asparaginase activity
FOC13_RS21300	COG1027	Aspartate ammonia-lyase
FOC13_RS21315	COG1063	alcohol dehydrogenase
FOC13_RS21345	COG1280	lysine exporter protein (LysE YggA)
FOC13_RS21350	COG3403	YqcI/YcgG family
FOC13_RS21355	COG5577	PFAM Coat F domain
FOC13_RS21370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS21375	COG0574	Belongs to the PEP-utilizing enzyme family
FOC13_RS21375	COG3848	Pyruvate phosphate dikinase
FOC13_RS21390	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC13_RS21420	COG1960	acyl-CoA dehydrogenase activity
FOC13_RS21430	COG0640	Transcriptional regulator
FOC13_RS21435	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS21450	COG1414	Transcriptional regulator
FOC13_RS21455	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC13_RS21460	COG1984	allophanate hydrolase subunit 2
FOC13_RS21490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC13_RS21535	COG4335	DNA alkylation repair
FOC13_RS21545	COG0833	amino acid
FOC13_RS21555	COG0730	response to heat
FOC13_RS21585	COG0596	Alpha beta hydrolase
FOC13_RS21590	COG0745	RESPONSE REGULATOR receiver
FOC13_RS21595	COG0642	Histidine kinase
FOC13_RS21615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS21635	COG0456	acetyltransferase
FOC13_RS21640	COG2207	Transcriptional regulator
FOC13_RS21665	COG0577	efflux transmembrane transporter activity
FOC13_RS21665	COG1136	(ABC) transporter
FOC13_RS21675	COG1725	Transcriptional regulator
FOC13_RS21710	COG1846	Transcriptional regulator
FOC13_RS21715	COG0778	Nitroreductase
FOC13_RS21725	COG0714	Associated with various cellular activities
FOC13_RS21750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC13_RS21760	COG0753	catalase activity
FOC13_RS21765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC13_RS21775	COG0463	Glycosyl transferase, family 2
FOC13_RS21800	COG0463	Glycosyl transferase, family 2
FOC13_RS21825	COG0714	Associated with various cellular activities
FOC13_RS21845	COG0346	lactoylglutathione lyase activity
FOC13_RS21850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS21860	COG3279	Response regulator of the LytR AlgR family
FOC13_RS21870	COG4377	Putative membrane peptidase family (DUF2324)
FOC13_RS21885	COG3655	Transcriptional regulator
FOC13_RS21895	COG1785	Belongs to the alkaline phosphatase family
FOC13_RS21900	COG3239	Fatty acid desaturase
FOC13_RS21905	COG1690	Belongs to the RtcB family
FOC13_RS21910	COG0833	amino acid
FOC13_RS21915	COG1414	Transcriptional regulator
FOC13_RS21920	COG4187	Peptidase family M20/M25/M40
FOC13_RS21925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC13_RS21930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC13_RS21940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS21960	COG2329	Antibiotic biosynthesis monooxygenase
FOC13_RS21995	COG2390	Transcriptional regulator
FOC13_RS22005	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC13_RS22015	COG1879	ABC-type sugar transport system periplasmic component
FOC13_RS22040	COG1595	DNA-templated transcription, initiation
FOC13_RS22050	COG3584	3D domain protein
FOC13_RS22050	COG1388	LysM domain
FOC13_RS22085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC13_RS22085	COG1605	Chorismate mutase
FOC13_RS22090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC13_RS22095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC13_RS22100	COG0287	Prephenate dehydrogenase
FOC13_RS22115	COG1309	transcriptional regulator
FOC13_RS22120	COG1033	growth of symbiont in host cell
FOC13_RS22120	COG2409	Drug exporters of the RND superfamily
FOC13_RS22125	COG1033	growth of symbiont in host cell
FOC13_RS22125	COG2409	Drug exporters of the RND superfamily
FOC13_RS22130	COG1033	growth of symbiont in host cell
FOC13_RS22130	COG2409	Drug exporters of the RND superfamily
FOC13_RS22140	COG0488	(ABC) transporter
FOC13_RS22145	COG1368	sulfuric ester hydrolase activity
FOC13_RS22150	COG0861	Integral membrane protein TerC family
FOC13_RS22160	COG0726	polysaccharide deacetylase
FOC13_RS22170	COG4912	Dna alkylation repair
FOC13_RS22190	COG2318	DinB family
FOC13_RS22195	COG0697	spore germination
FOC13_RS22220	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC13_RS22260	COG1116	anion transmembrane transporter activity
FOC13_RS22265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC13_RS22270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC13_RS22275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC13_RS22285	COG0628	permease
FOC13_RS22345	COG5146	pantothenate kinase activity
FOC13_RS22350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC13_RS22355	COG0436	Aminotransferase
FOC13_RS22390	COG2226	methyltransferase
FOC13_RS22405	COG2261	transglycosylase associated protein
FOC13_RS22425	COG0477	Major facilitator Superfamily
FOC13_RS22425	COG2814	Major facilitator Superfamily
FOC13_RS22430	COG4533	DNA binding
FOC13_RS22435	COG0789	Transcriptional regulator
FOC13_RS22440	COG1664	Polymer-forming cytoskeletal
FOC13_RS22450	COG2814	Major facilitator Superfamily
FOC13_RS22470	COG1307	EDD domain protein, DegV family
FOC13_RS22485	COG1164	Oligoendopeptidase f
FOC13_RS22525	COG5002	protein histidine kinase activity
FOC13_RS22530	COG2936	dipeptidyl-peptidase activity
FOC13_RS22575	COG4948	Mandelate Racemase Muconate Lactonizing
FOC13_RS22585	COG4166	transmembrane transport
FOC13_RS22590	COG0519	Catalyzes the synthesis of GMP from XMP
FOC13_RS22595	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC13_RS22610	COG0586	Pfam SNARE associated Golgi protein
FOC13_RS22650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC13_RS22655	COG3938	Belongs to the proline racemase family
FOC13_RS22665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC13_RS22670	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS22675	COG1115	amino acid carrier protein
FOC13_RS22680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC13_RS22695	COG3397	chitin binding
FOC13_RS22720	COG4637	Psort location Cytoplasmic, score
FOC13_RS22740	COG0514	ATP-dependent DNA helicase (RecQ)
FOC13_RS22745	COG2105	PFAM AIG2 family protein
FOC13_RS22760	COG3973	AAA domain
FOC13_RS22810	COG0658	competence protein
FOC13_RS22810	COG2333	competence protein COMEC
FOC13_RS22830	COG2205	protein histidine kinase activity
FOC13_RS22845	COG3397	chitin binding
FOC13_RS22850	COG2153	protein acetylation
FOC13_RS22855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC13_RS22870	COG0740	serine-type endopeptidase activity
FOC13_RS22880	COG0517	IMP dehydrogenase activity
FOC13_RS22880	COG4175	Glycine betaine
FOC13_RS22885	COG4176	ABC-type proline glycine betaine transport system permease component
FOC13_RS22915	COG0456	acetyltransferase
FOC13_RS22915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC13_RS22920	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS22930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC13_RS22935	COG0022	dehydrogenase e1 component
FOC13_RS22940	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC13_RS22945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC13_RS22960	COG1959	2 iron, 2 sulfur cluster binding
FOC13_RS22980	COG1349	DNA-binding transcription factor activity
FOC13_RS22995	COG3284	Transcriptional regulator
FOC13_RS23025	COG1309	transcriptional regulator
FOC13_RS23030	COG3844	kynureninase activity
FOC13_RS23035	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC13_RS23040	COG3483	tryptophan 2,3-dioxygenase activity
FOC13_RS23055	COG3773	Cell wall hydrolase
FOC13_RS23055	COG3409	Peptidoglycan-binding domain 1 protein
FOC13_RS23060	COG2959	enzyme of heme biosynthesis
FOC13_RS23075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS23080	COG4129	membrane
FOC13_RS23110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS23115	COG0697	spore germination
FOC13_RS23125	COG0201	protein transport
FOC13_RS23145	COG3227	Zinc metalloprotease (Elastase)
FOC13_RS23150	COG1523	belongs to the glycosyl hydrolase 13 family
FOC13_RS23165	COG0076	glutamate decarboxylase activity
FOC13_RS23185	COG1011	Hydrolase
FOC13_RS23210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC13_RS23250	COG0322	excinuclease ABC activity
FOC13_RS23265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC13_RS23315	COG3878	Protein conserved in bacteria
FOC13_RS23350	COG1051	belongs to the nudix hydrolase family
FOC13_RS23355	COG0592	DNA-directed DNA polymerase activity
FOC13_RS23360	COG2816	NAD+ diphosphatase activity
FOC13_RS23375	COG2223	nitrite transmembrane transporter activity
FOC13_RS23405	COG0697	spore germination
FOC13_RS23425	COG0584	glycerophosphoryl diester phosphodiesterase
FOC13_RS23440	COG2814	Major facilitator Superfamily
FOC13_RS23470	COG0693	protein deglycase activity
FOC13_RS23505	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC13_RS23520	COG0604	alcohol dehydrogenase
FOC13_RS23535	COG2205	protein histidine kinase activity
FOC13_RS23550	COG1122	ATPase activity
FOC13_RS23560	COG1794	racemase activity, acting on amino acids and derivatives
FOC13_RS23565	COG1819	glycosyl
FOC13_RS23575	COG5002	protein histidine kinase activity
FOC13_RS23585	COG0561	phosphatase activity
FOC13_RS23620	COG2124	cytochrome p450
FOC13_RS23685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC13_RS23695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS23700	COG0460	homoserine dehydrogenase
FOC13_RS23725	COG1136	(ABC) transporter
FOC13_RS23755	COG0745	RESPONSE REGULATOR receiver
FOC13_RS23765	COG3773	Cell wall hydrolase
FOC13_RS23790	COG1063	alcohol dehydrogenase
FOC13_RS23805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS23825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC13_RS23840	COG2814	Major facilitator Superfamily
FOC13_RS23850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC13_RS23865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC13_RS23865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC13_RS23905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC13_RS23930	COG1686	Belongs to the peptidase S11 family
FOC13_RS23935	COG2318	DinB family
FOC13_RS23945	COG0572	uridine kinase
FOC13_RS23950	COG1247	-acetyltransferase
FOC13_RS23960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC13_RS23965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC13_RS23970	COG1024	Enoyl-CoA hydratase
FOC13_RS23975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC13_RS23980	COG0511	ligase activity, forming carbon-carbon bonds
FOC13_RS23985	COG0439	Biotin carboxylase
FOC13_RS23990	COG1960	acyl-CoA dehydrogenase activity
FOC13_RS24005	COG1309	transcriptional regulator
FOC13_RS24015	COG1131	(ABC) transporter
FOC13_RS24030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC13_RS24035	COG1252	NADH dehydrogenase
FOC13_RS24050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS24070	COG1309	transcriptional regulator
FOC13_RS24090	COG1876	peptidase activity
FOC13_RS24105	COG1476	TRANSCRIPTIONal
FOC13_RS24110	COG0457	Tetratricopeptide repeat
FOC13_RS24135	COG3718	enzyme involved in inositol metabolism
FOC13_RS24155	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS24165	COG0673	inositol 2-dehydrogenase activity
FOC13_RS24170	COG2814	Major facilitator Superfamily
FOC13_RS24175	COG1609	Transcriptional regulator
FOC13_RS24180	COG0671	phosphoesterase, PA-phosphatase related
FOC13_RS24185	COG2367	Beta-lactamase
FOC13_RS24195	COG0768	penicillin binding
FOC13_RS24205	COG1595	DNA-templated transcription, initiation
FOC13_RS24220	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC13_RS24250	COG1846	Transcriptional regulator
FOC13_RS24255	COG3961	Belongs to the TPP enzyme family
FOC13_RS24260	COG2226	methyltransferase
FOC13_RS24270	COG3615	Tellurite resistance protein tehB
FOC13_RS24270	COG0500	methyltransferase
FOC13_RS24275	COG1136	(ABC) transporter
FOC13_RS24275	COG0577	efflux transmembrane transporter activity
FOC13_RS24290	COG1309	transcriptional regulator
FOC13_RS24320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS24340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC13_RS24345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC13_RS24350	COG2971	BadF BadG BcrA BcrD
FOC13_RS24400	COG1595	DNA-templated transcription, initiation
FOC13_RS24430	COG1396	sequence-specific DNA binding
FOC13_RS24450	COG1132	(ABC) transporter
FOC13_RS24455	COG1132	(ABC) transporter
FOC13_RS24470	COG2258	MOSC domain
FOC13_RS24475	COG0583	DNA-binding transcription factor activity
FOC13_RS24490	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC13_RS24495	COG0583	DNA-binding transcription factor activity
FOC13_RS24530	COG0561	phosphatase activity
FOC13_RS24535	COG0010	Belongs to the arginase family
FOC13_RS24550	COG1278	Cold shock
FOC13_RS24560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC13_RS24600	COG1247	-acetyltransferase
FOC13_RS24635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC13_RS24680	COG2226	methyltransferase
FOC13_RS24700	COG2814	Major facilitator Superfamily
FOC13_RS24705	COG0596	Alpha beta hydrolase
FOC13_RS24720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC13_RS24725	COG1187	pseudouridine synthase activity
FOC13_RS24730	COG2329	Antibiotic biosynthesis monooxygenase
FOC13_RS24745	COG1115	amino acid carrier protein
FOC13_RS24755	COG2318	DinB family
FOC13_RS24765	COG0776	regulation of translation
FOC13_RS24780	COG2814	Major facilitator Superfamily
FOC13_RS24785	COG3251	PFAM MbtH domain protein
FOC13_RS24790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC13_RS24795	COG3433	isochorismatase activity
FOC13_RS24795	COG1535	isochorismatase
FOC13_RS24800	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC13_RS24805	COG1169	isochorismate synthase
FOC13_RS24810	COG1028	Short-chain dehydrogenase reductase Sdr
FOC13_RS24815	COG2223	nitrite transmembrane transporter activity
FOC13_RS24835	COG0419	ATPase involved in DNA repair
FOC13_RS24840	COG0420	3'-5' exonuclease activity
FOC13_RS24855	COG1024	Enoyl-CoA hydratase
FOC13_RS24860	COG1280	lysine exporter protein (LysE YggA)
FOC13_RS24865	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS24870	COG2084	Dehydrogenase
FOC13_RS24875	COG1960	acyl-CoA dehydrogenase activity
FOC13_RS24880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC13_RS24885	COG2079	MmgE PrpD family protein
FOC13_RS24890	COG0372	Belongs to the citrate synthase family
FOC13_RS24895	COG4841	protein insertion into membrane
FOC13_RS24900	COG2814	Major facilitator Superfamily
FOC13_RS24905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC13_RS24905	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC13_RS24945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC13_RS25035	COG1715	Restriction endonuclease
FOC13_RS25035	COG1787	Restriction endonuclease
FOC13_RS25065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC13_RS25070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC13_RS25075	COG0671	phosphoesterase, PA-phosphatase related
FOC13_RS25080	COG4326	sporulation control protein
FOC13_RS25120	COG1509	lysine 2,3-aminomutase activity
FOC13_RS25125	COG3829	transcription factor binding
FOC13_RS25130	COG0456	acetyltransferase
FOC13_RS25135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC13_RS25140	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC13_RS25145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC13_RS25150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC13_RS25165	COG5506	Protein of unknown function (DUF1694)
FOC13_RS25170	COG1012	belongs to the aldehyde dehydrogenase family
FOC13_RS25175	COG1253	flavin adenine dinucleotide binding
FOC13_RS25210	COG1174	glycine betaine transport
FOC13_RS25215	COG0517	IMP dehydrogenase activity
FOC13_RS25215	COG1125	glycine betaine transport
FOC13_RS25245	COG1070	Carbohydrate kinase
FOC13_RS25270	COG1064	alcohol dehydrogenase
FOC13_RS25280	COG2197	response regulator
FOC13_RS25285	COG2203	Gaf domain
FOC13_RS25285	COG4585	Histidine kinase
FOC13_RS25290	COG0668	transmembrane transport
FOC13_RS25300	COG1051	belongs to the nudix hydrolase family
FOC13_RS25325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC13_RS25330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC13_RS25345	COG0367	asparagine synthase
FOC13_RS25350	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC13_RS25355	COG1999	signal sequence binding
FOC13_RS25360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC13_RS25365	COG1307	EDD domain protein, DegV family
FOC13_RS25375	COG0805	protein transport
FOC13_RS25385	COG1272	protein, Hemolysin III
FOC13_RS25395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC13_RS25400	COG0768	penicillin binding
FOC13_RS25415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC13_RS25435	COG0546	phosphoglycolate phosphatase activity
FOC13_RS25450	COG1131	(ABC) transporter
FOC13_RS25465	COG0456	acetyltransferase
FOC13_RS25475	COG1794	racemase activity, acting on amino acids and derivatives
FOC13_RS25480	COG1454	alcohol dehydrogenase
FOC13_RS25485	COG2610	gluconate transmembrane transporter activity
FOC13_RS25510	COG0733	neurotransmitter:sodium symporter activity
FOC13_RS25525	COG5002	protein histidine kinase activity
FOC13_RS25525	COG3850	Histidine kinase
FOC13_RS25530	COG0745	RESPONSE REGULATOR receiver
FOC13_RS25535	COG0471	metal ion transport
FOC13_RS25540	COG1929	Belongs to the glycerate kinase type-1 family
FOC13_RS25610	COG1674	ftsk spoiiie
FOC13_RS25630	COG0017	Asparaginyl-tRNA synthetase
FOC13_RS25650	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC13_RS25675	COG0018	arginyl-trna synthetase
FOC13_RS25680	COG2521	methyltransferase
FOC13_RS25680	COG2136	Putative SAM-dependent methyltransferase
FOC13_RS25695	COG1413	lyase activity
FOC13_RS25710	COG0629	single-stranded DNA binding
FOC13_RS25725	COG0488	(ABC) transporter
FOC13_RS25730	COG1418	mRNA catabolic process
FOC13_RS25745	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS25760	COG2359	stage V sporulation protein S
FOC13_RS25795	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC13_RS25800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC13_RS25805	COG2146	nitrite reductase [NAD(P)H] activity
FOC13_RS25810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC13_RS25810	COG1587	Uroporphyrinogen-III synthase
FOC13_RS25820	COG1648	precorrin-2 dehydrogenase activity
FOC13_RS25835	COG2223	nitrite transmembrane transporter activity
FOC13_RS25845	COG0314	molybdopterin synthase activity
FOC13_RS25850	COG0303	'Molybdopterin
FOC13_RS25855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC13_RS25860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC13_RS25865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC13_RS25885	COG2181	nitrate reductase activity
FOC13_RS25890	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC13_RS25895	COG1140	nitrate reductase beta subunit
FOC13_RS25900	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC13_RS25915	COG0714	Associated with various cellular activities
FOC13_RS25920	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC13_RS25925	COG1305	Transglutaminase-like
FOC13_RS25930	COG0386	Belongs to the glutathione peroxidase family
FOC13_RS25955	COG1595	DNA-templated transcription, initiation
FOC13_RS25960	COG0604	alcohol dehydrogenase
FOC13_RS25970	COG0346	lactoylglutathione lyase activity
FOC13_RS25995	COG2226	methyltransferase
FOC13_RS26020	COG3874	Sporulation protein YtfJ
FOC13_RS26070	COG0456	acetyltransferase
FOC13_RS26095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC13_RS26100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC13_RS26105	COG1819	glycosyl
FOC13_RS26125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC13_RS26135	COG0561	phosphatase activity
FOC13_RS26155	COG2211	Major facilitator Superfamily
FOC13_RS26160	COG0154	amidase activity
FOC13_RS26170	COG1876	peptidase activity
FOC13_RS26180	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC13_RS26200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC13_RS26205	COG1114	Component of the transport system for branched-chain amino acids
FOC13_RS26220	COG1253	flavin adenine dinucleotide binding
FOC13_RS26225	COG2839	Protein conserved in bacteria
FOC13_RS26230	COG0702	epimerase
FOC13_RS26245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC13_RS26255	COG1607	acyl-coa hydrolase
FOC13_RS26260	COG3689	TIGRFAM TIGR03943 family protein
FOC13_RS26265	COG0701	Predicted permease
FOC13_RS26275	COG2244	polysaccharide biosynthetic process
FOC13_RS26280	COG0586	Pfam SNARE associated Golgi protein
FOC13_RS26285	COG1051	belongs to the nudix hydrolase family
FOC13_RS26290	COG5337	Spore coat protein CotH
FOC13_RS26300	COG0406	alpha-ribazole phosphatase activity
FOC13_RS26315	COG4166	transmembrane transport
FOC13_RS26325	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC13_RS26335	COG0702	epimerase
FOC13_RS26340	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC13_RS26340	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC13_RS26390	COG0456	acetyltransferase
FOC13_RS26395	COG0523	cobalamin synthesis protein
FOC13_RS26400	COG4989	oxidoreductase activity
FOC13_RS26410	COG1231	oxidoreductase activity
FOC13_RS26420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC13_RS26435	COG0783	Belongs to the Dps family
FOC13_RS26440	COG3949	Membrane
FOC13_RS26455	COG0840	transmembrane signaling receptor activity
FOC13_RS26480	COG2814	Major facilitator Superfamily
FOC13_RS26485	COG0667	Aldo Keto reductase
FOC13_RS26490	COG0640	Transcriptional regulator
FOC13_RS26495	COG1404	Belongs to the peptidase S8 family
FOC13_RS26500	COG2002	toxin-antitoxin pair type II binding
FOC13_RS26540	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC13_RS26550	COG1279	arginine transmembrane transporter activity
FOC13_RS26565	COG1082	Xylose isomerase domain protein TIM barrel
FOC13_RS26580	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS26585	COG4264	IucA IucC family
FOC13_RS26595	COG1247	-acetyltransferase
FOC13_RS26600	COG1285	pathogenesis
FOC13_RS26610	COG0726	polysaccharide deacetylase
FOC13_RS26615	COG5002	protein histidine kinase activity
FOC13_RS26620	COG0745	RESPONSE REGULATOR receiver
FOC13_RS26630	COG1316	TRANSCRIPTIONal
FOC13_RS26655	COG0460	homoserine dehydrogenase
FOC13_RS26675	COG0726	polysaccharide deacetylase
FOC13_RS26690	COG0300	oxidoreductase activity
FOC13_RS26700	COG5002	protein histidine kinase activity
FOC13_RS26705	COG0745	RESPONSE REGULATOR receiver
FOC13_RS26720	COG1388	LysM domain
FOC13_RS26720	COG0791	NLP P60 protein
FOC13_RS26735	COG1686	Belongs to the peptidase S11 family
FOC13_RS26755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC13_RS26760	COG4988	ABC transporter
FOC13_RS26765	COG1294	oxidase, subunit
FOC13_RS26770	COG1271	oxidase subunit
FOC13_RS26780	COG1846	Transcriptional regulator
FOC13_RS26790	COG1942	4-Oxalocrotonate Tautomerase
FOC13_RS26800	COG0583	DNA-binding transcription factor activity
FOC13_RS26820	COG0411	ABC transporter
FOC13_RS26830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC13_RS26835	COG2030	dehydratase
FOC13_RS26840	COG0318	PFAM AMP-dependent synthetase and ligase
FOC13_RS26855	COG0523	cobalamin synthesis protein
FOC13_RS26860	COG1231	oxidoreductase activity
FOC13_RS26865	COG0039	L-malate dehydrogenase activity
FOC13_RS26870	COG0628	permease
FOC13_RS26880	COG0778	Nitroreductase
FOC13_RS26885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC13_RS26890	COG1959	2 iron, 2 sulfur cluster binding
FOC13_RS26895	COG0583	DNA-binding transcription factor activity
FOC13_RS26900	COG0697	spore germination
FOC13_RS26910	COG4549	nuclear export factor GLE1
FOC13_RS26915	COG1276	copper resistance
FOC13_RS26915	COG2372	response to copper ion
FOC13_RS26930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC13_RS26960	COG2132	Multicopper oxidase
FOC13_RS26965	COG0006	proline dipeptidase activity
FOC13_RS26985	COG4224	UPF0291 protein
FOC13_RS27000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC13_RS27005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC13_RS27015	COG2390	Transcriptional regulator
FOC13_RS27045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC13_RS27060	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC13_RS27095	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)