locus-tag	class	description
FOC14_RS00015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS00050	COG1247	-acetyltransferase
FOC14_RS00090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS00100	COG1278	Cold shock
FOC14_RS00115	COG0010	Belongs to the arginase family
FOC14_RS00120	COG0561	phosphatase activity
FOC14_RS00155	COG0583	DNA-binding transcription factor activity
FOC14_RS00160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC14_RS00175	COG0583	DNA-binding transcription factor activity
FOC14_RS00180	COG2258	MOSC domain
FOC14_RS00195	COG1132	(ABC) transporter
FOC14_RS00200	COG1132	(ABC) transporter
FOC14_RS00220	COG1396	sequence-specific DNA binding
FOC14_RS00250	COG1595	DNA-templated transcription, initiation
FOC14_RS00300	COG2971	BadF BadG BcrA BcrD
FOC14_RS00305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC14_RS00310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC14_RS00330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS00360	COG1309	transcriptional regulator
FOC14_RS00375	COG1136	(ABC) transporter
FOC14_RS00375	COG0577	efflux transmembrane transporter activity
FOC14_RS00380	COG3615	Tellurite resistance protein tehB
FOC14_RS00380	COG0500	methyltransferase
FOC14_RS00390	COG2226	methyltransferase
FOC14_RS00395	COG3961	Belongs to the TPP enzyme family
FOC14_RS00400	COG1846	Transcriptional regulator
FOC14_RS00430	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC14_RS00445	COG1595	DNA-templated transcription, initiation
FOC14_RS00455	COG0768	penicillin binding
FOC14_RS00465	COG2367	Beta-lactamase
FOC14_RS00470	COG0671	phosphoesterase, PA-phosphatase related
FOC14_RS00475	COG1609	Transcriptional regulator
FOC14_RS00480	COG2814	Major facilitator Superfamily
FOC14_RS00485	COG0673	inositol 2-dehydrogenase activity
FOC14_RS00495	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS00515	COG3718	enzyme involved in inositol metabolism
FOC14_RS00540	COG0457	Tetratricopeptide repeat
FOC14_RS00545	COG1476	TRANSCRIPTIONal
FOC14_RS00560	COG1876	peptidase activity
FOC14_RS00580	COG1309	transcriptional regulator
FOC14_RS00600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS00615	COG1252	NADH dehydrogenase
FOC14_RS00620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC14_RS00635	COG1131	(ABC) transporter
FOC14_RS00645	COG1309	transcriptional regulator
FOC14_RS00660	COG1960	acyl-CoA dehydrogenase activity
FOC14_RS00665	COG0439	Biotin carboxylase
FOC14_RS00670	COG0511	ligase activity, forming carbon-carbon bonds
FOC14_RS00675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC14_RS00680	COG1024	Enoyl-CoA hydratase
FOC14_RS00685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC14_RS00690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC14_RS00700	COG1247	-acetyltransferase
FOC14_RS00705	COG0572	uridine kinase
FOC14_RS00715	COG2318	DinB family
FOC14_RS00720	COG1686	Belongs to the peptidase S11 family
FOC14_RS00745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC14_RS00785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC14_RS00785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC14_RS00800	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC14_RS00810	COG2814	Major facilitator Superfamily
FOC14_RS00825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC14_RS00845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS00860	COG1063	alcohol dehydrogenase
FOC14_RS00885	COG3773	Cell wall hydrolase
FOC14_RS00895	COG0745	RESPONSE REGULATOR receiver
FOC14_RS00925	COG1136	(ABC) transporter
FOC14_RS00950	COG0460	homoserine dehydrogenase
FOC14_RS00955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC14_RS01030	COG2124	cytochrome p450
FOC14_RS01065	COG0561	phosphatase activity
FOC14_RS01075	COG5002	protein histidine kinase activity
FOC14_RS01085	COG1819	glycosyl
FOC14_RS01090	COG1794	racemase activity, acting on amino acids and derivatives
FOC14_RS01100	COG1122	ATPase activity
FOC14_RS01115	COG2205	protein histidine kinase activity
FOC14_RS01130	COG0604	alcohol dehydrogenase
FOC14_RS01145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC14_RS01180	COG0693	protein deglycase activity
FOC14_RS01210	COG2814	Major facilitator Superfamily
FOC14_RS01225	COG0584	glycerophosphoryl diester phosphodiesterase
FOC14_RS01245	COG0697	spore germination
FOC14_RS01275	COG2223	nitrite transmembrane transporter activity
FOC14_RS01290	COG2816	NAD+ diphosphatase activity
FOC14_RS01295	COG0592	DNA-directed DNA polymerase activity
FOC14_RS01300	COG1051	belongs to the nudix hydrolase family
FOC14_RS01335	COG3878	Protein conserved in bacteria
FOC14_RS01385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC14_RS01400	COG0322	excinuclease ABC activity
FOC14_RS01440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC14_RS01465	COG1011	Hydrolase
FOC14_RS01485	COG0076	glutamate decarboxylase activity
FOC14_RS01500	COG1523	belongs to the glycosyl hydrolase 13 family
FOC14_RS01505	COG3227	Zinc metalloprotease (Elastase)
FOC14_RS01525	COG0201	protein transport
FOC14_RS01535	COG0697	spore germination
FOC14_RS01540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS01570	COG4129	membrane
FOC14_RS01575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS01590	COG2959	enzyme of heme biosynthesis
FOC14_RS01595	COG3409	Peptidoglycan-binding domain 1 protein
FOC14_RS01595	COG3773	Cell wall hydrolase
FOC14_RS01610	COG3483	tryptophan 2,3-dioxygenase activity
FOC14_RS01615	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOC14_RS01620	COG3844	kynureninase activity
FOC14_RS01625	COG1309	transcriptional regulator
FOC14_RS01655	COG3284	Transcriptional regulator
FOC14_RS01670	COG1349	DNA-binding transcription factor activity
FOC14_RS01690	COG1959	2 iron, 2 sulfur cluster binding
FOC14_RS01705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC14_RS01710	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC14_RS01715	COG0022	dehydrogenase e1 component
FOC14_RS01720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC14_RS01730	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS01735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC14_RS01735	COG0456	acetyltransferase
FOC14_RS01765	COG4176	ABC-type proline glycine betaine transport system permease component
FOC14_RS01770	COG0517	IMP dehydrogenase activity
FOC14_RS01770	COG4175	Glycine betaine
FOC14_RS01780	COG0740	serine-type endopeptidase activity
FOC14_RS01795	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC14_RS01800	COG2153	protein acetylation
FOC14_RS01805	COG3397	chitin binding
FOC14_RS01820	COG2205	protein histidine kinase activity
FOC14_RS01840	COG0658	competence protein
FOC14_RS01840	COG2333	competence protein COMEC
FOC14_RS01890	COG3973	AAA domain
FOC14_RS01905	COG2105	PFAM AIG2 family protein
FOC14_RS01910	COG0514	ATP-dependent DNA helicase (RecQ)
FOC14_RS01930	COG4637	Psort location Cytoplasmic, score
FOC14_RS01955	COG3397	chitin binding
FOC14_RS01970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC14_RS01975	COG1115	amino acid carrier protein
FOC14_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS01985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC14_RS01995	COG3938	Belongs to the proline racemase family
FOC14_RS02000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC14_RS02040	COG0586	Pfam SNARE associated Golgi protein
FOC14_RS02055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC14_RS02060	COG0519	Catalyzes the synthesis of GMP from XMP
FOC14_RS02065	COG4166	transmembrane transport
FOC14_RS02075	COG4948	Mandelate Racemase Muconate Lactonizing
FOC14_RS02120	COG2936	dipeptidyl-peptidase activity
FOC14_RS02125	COG5002	protein histidine kinase activity
FOC14_RS02165	COG1164	Oligoendopeptidase f
FOC14_RS02180	COG1307	EDD domain protein, DegV family
FOC14_RS02200	COG2814	Major facilitator Superfamily
FOC14_RS02210	COG1664	Polymer-forming cytoskeletal
FOC14_RS02215	COG0789	Transcriptional regulator
FOC14_RS02220	COG4533	DNA binding
FOC14_RS02225	COG0477	Major facilitator Superfamily
FOC14_RS02225	COG2814	Major facilitator Superfamily
FOC14_RS02245	COG2261	transglycosylase associated protein
FOC14_RS02260	COG2226	methyltransferase
FOC14_RS02295	COG0436	Aminotransferase
FOC14_RS02300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC14_RS02305	COG5146	pantothenate kinase activity
FOC14_RS02365	COG0628	permease
FOC14_RS02375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC14_RS02380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC14_RS02385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC14_RS02390	COG1116	anion transmembrane transporter activity
FOC14_RS02430	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC14_RS02455	COG0697	spore germination
FOC14_RS02460	COG2318	DinB family
FOC14_RS02480	COG4912	Dna alkylation repair
FOC14_RS02490	COG0726	polysaccharide deacetylase
FOC14_RS02500	COG0861	Integral membrane protein TerC family
FOC14_RS02505	COG1368	sulfuric ester hydrolase activity
FOC14_RS02510	COG0488	(ABC) transporter
FOC14_RS02520	COG2409	Drug exporters of the RND superfamily
FOC14_RS02520	COG1033	growth of symbiont in host cell
FOC14_RS02525	COG2409	Drug exporters of the RND superfamily
FOC14_RS02525	COG1033	growth of symbiont in host cell
FOC14_RS02530	COG1033	growth of symbiont in host cell
FOC14_RS02530	COG2409	Drug exporters of the RND superfamily
FOC14_RS02535	COG1309	transcriptional regulator
FOC14_RS02550	COG0287	Prephenate dehydrogenase
FOC14_RS02555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC14_RS02560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC14_RS02565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC14_RS02565	COG1605	Chorismate mutase
FOC14_RS02600	COG1388	LysM domain
FOC14_RS02600	COG3584	3D domain protein
FOC14_RS02610	COG1595	DNA-templated transcription, initiation
FOC14_RS02635	COG1879	ABC-type sugar transport system periplasmic component
FOC14_RS02645	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC14_RS02655	COG2390	Transcriptional regulator
FOC14_RS02690	COG2329	Antibiotic biosynthesis monooxygenase
FOC14_RS02710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS02720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC14_RS02725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC14_RS02730	COG4187	Peptidase family M20/M25/M40
FOC14_RS02735	COG1414	Transcriptional regulator
FOC14_RS02740	COG0833	amino acid
FOC14_RS02745	COG1690	Belongs to the RtcB family
FOC14_RS02750	COG3239	Fatty acid desaturase
FOC14_RS02755	COG1785	Belongs to the alkaline phosphatase family
FOC14_RS02765	COG3655	Transcriptional regulator
FOC14_RS02780	COG4377	Putative membrane peptidase family (DUF2324)
FOC14_RS02790	COG3279	Response regulator of the LytR AlgR family
FOC14_RS02800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS02805	COG0346	lactoylglutathione lyase activity
FOC14_RS02825	COG0714	Associated with various cellular activities
FOC14_RS02850	COG0463	Glycosyl transferase, family 2
FOC14_RS02875	COG0463	Glycosyl transferase, family 2
FOC14_RS02885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC14_RS02890	COG0753	catalase activity
FOC14_RS02900	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC14_RS02925	COG0714	Associated with various cellular activities
FOC14_RS02935	COG0778	Nitroreductase
FOC14_RS02940	COG1846	Transcriptional regulator
FOC14_RS02975	COG1725	Transcriptional regulator
FOC14_RS02985	COG0577	efflux transmembrane transporter activity
FOC14_RS02985	COG1136	(ABC) transporter
FOC14_RS03010	COG2207	Transcriptional regulator
FOC14_RS03015	COG0456	acetyltransferase
FOC14_RS03035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS03055	COG0642	Histidine kinase
FOC14_RS03060	COG0745	RESPONSE REGULATOR receiver
FOC14_RS03065	COG0596	Alpha beta hydrolase
FOC14_RS03095	COG0730	response to heat
FOC14_RS03105	COG0833	amino acid
FOC14_RS03115	COG4335	DNA alkylation repair
FOC14_RS03160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC14_RS03190	COG1984	allophanate hydrolase subunit 2
FOC14_RS03195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC14_RS03200	COG1414	Transcriptional regulator
FOC14_RS03215	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS03220	COG0640	Transcriptional regulator
FOC14_RS03230	COG1960	acyl-CoA dehydrogenase activity
FOC14_RS03260	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC14_RS03275	COG0574	Belongs to the PEP-utilizing enzyme family
FOC14_RS03275	COG3848	Pyruvate phosphate dikinase
FOC14_RS03280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS03295	COG5577	PFAM Coat F domain
FOC14_RS03300	COG3403	YqcI/YcgG family
FOC14_RS03305	COG1280	lysine exporter protein (LysE YggA)
FOC14_RS03335	COG1063	alcohol dehydrogenase
FOC14_RS03350	COG1027	Aspartate ammonia-lyase
FOC14_RS03355	COG0252	asparaginase activity
FOC14_RS03360	COG1396	sequence-specific DNA binding
FOC14_RS03370	COG0322	excinuclease ABC activity
FOC14_RS03375	COG0531	amino acid
FOC14_RS03380	COG1114	Component of the transport system for branched-chain amino acids
FOC14_RS03385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC14_RS03395	COG0281	malic enzyme
FOC14_RS03420	COG0784	Response regulator, receiver
FOC14_RS03430	COG2066	Belongs to the glutaminase family
FOC14_RS03465	COG0737	Belongs to the 5'-nucleotidase family
FOC14_RS03470	COG0753	catalase activity
FOC14_RS03475	COG2267	carboxylic ester hydrolase activity
FOC14_RS03480	COG1335	isochorismatase
FOC14_RS03500	COG0583	DNA-binding transcription factor activity
FOC14_RS03505	COG1846	Transcriptional regulator
FOC14_RS03545	COG0415	Belongs to the DNA photolyase family
FOC14_RS03550	COG0288	reversible hydration of carbon dioxide
FOC14_RS03560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC14_RS03565	COG5609	conserved protein (DUF2294)
FOC14_RS03580	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC14_RS03585	COG2267	carboxylic ester hydrolase activity
FOC14_RS03590	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC14_RS03595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC14_RS03600	COG1121	(ABC) transporter
FOC14_RS03630	COG0798	PFAM Bile acid sodium symporter
FOC14_RS03635	COG0346	lactoylglutathione lyase activity
FOC14_RS03640	COG0640	Transcriptional regulator
FOC14_RS03655	COG0443	Heat shock 70 kDa protein
FOC14_RS03670	COG1522	sequence-specific DNA binding
FOC14_RS03685	COG0346	lactoylglutathione lyase activity
FOC14_RS03710	COG2169	Transcriptional regulator
FOC14_RS03750	COG2814	Major facilitator Superfamily
FOC14_RS03775	COG0745	RESPONSE REGULATOR receiver
FOC14_RS03780	COG3850	Histidine kinase
FOC14_RS03780	COG5002	protein histidine kinase activity
FOC14_RS03805	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC14_RS03825	COG1476	TRANSCRIPTIONal
FOC14_RS03840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS03845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC14_RS03855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC14_RS03860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC14_RS03875	COG1136	(ABC) transporter
FOC14_RS03880	COG0577	efflux transmembrane transporter activity
FOC14_RS03895	COG5002	protein histidine kinase activity
FOC14_RS03895	COG3850	Histidine kinase
FOC14_RS03905	COG2364	Membrane
FOC14_RS03910	COG1846	Transcriptional regulator
FOC14_RS03920	COG2808	Putative FMN-binding domain
FOC14_RS03925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS03930	COG2271	Major facilitator Superfamily
FOC14_RS03935	COG1556	Lactate utilization protein
FOC14_RS03940	COG1139	Iron-sulfur cluster binding protein
FOC14_RS03950	COG0583	DNA-binding transcription factor activity
FOC14_RS03960	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC14_RS03980	COG0738	Major facilitator superfamily
FOC14_RS03985	COG0673	inositol 2-dehydrogenase activity
FOC14_RS03990	COG0561	phosphatase activity
FOC14_RS04000	COG1609	Transcriptional regulator
FOC14_RS04005	COG0457	Tetratricopeptide repeat
FOC14_RS04020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC14_RS04050	COG0534	Mate efflux family protein
FOC14_RS04070	COG2814	Major facilitator Superfamily
FOC14_RS04075	COG1309	transcriptional regulator
FOC14_RS04090	COG0814	amino acid
FOC14_RS04095	COG1760	l-serine dehydratase
FOC14_RS04100	COG1760	l-serine dehydratase
FOC14_RS04110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC14_RS04115	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC14_RS04125	COG1335	isochorismatase
FOC14_RS04130	COG1522	sequence-specific DNA binding
FOC14_RS04135	COG0531	amino acid
FOC14_RS04150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC14_RS04170	COG1595	DNA-templated transcription, initiation
FOC14_RS04185	COG0662	Cupin 2, conserved barrel domain protein
FOC14_RS04190	COG2207	Transcriptional regulator
FOC14_RS04190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS04240	COG0477	Major facilitator Superfamily
FOC14_RS04250	COG1846	Transcriptional regulator
FOC14_RS04255	COG2814	Major facilitator Superfamily
FOC14_RS04270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC14_RS04275	COG1131	(ABC) transporter
FOC14_RS04295	COG2076	Multidrug Resistance protein
FOC14_RS04300	COG1309	transcriptional regulator
FOC14_RS04310	COG2031	fatty acid transporter
FOC14_RS04320	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC14_RS04350	COG1122	ATPase activity
FOC14_RS04355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC14_RS04370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC14_RS04375	COG1288	antiporter activity
FOC14_RS04380	COG2356	endonuclease I
FOC14_RS04395	COG3620	sequence-specific DNA binding
FOC14_RS04400	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC14_RS04405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC14_RS04410	COG0124	histidyl-tRNA synthetase
FOC14_RS04425	COG1733	regulation of RNA biosynthetic process
FOC14_RS04430	COG0778	Nitroreductase
FOC14_RS04450	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS04460	COG1131	(ABC) transporter
FOC14_RS04485	COG1011	Hydrolase
FOC14_RS04520	COG0346	lactoylglutathione lyase activity
FOC14_RS04525	COG1940	carbohydrate kinase activity
FOC14_RS04530	COG0738	Major facilitator superfamily
FOC14_RS04535	COG0110	maltose O-acetyltransferase activity
FOC14_RS04545	COG1136	(ABC) transporter
FOC14_RS04550	COG0180	Tryptophanyl-tRNA synthetase
FOC14_RS04555	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC14_RS04560	COG0628	permease
FOC14_RS04575	COG2226	methyltransferase
FOC14_RS04585	COG0477	Major facilitator Superfamily
FOC14_RS04615	COG1253	flavin adenine dinucleotide binding
FOC14_RS04620	COG0789	Transcriptional regulator
FOC14_RS04625	COG0697	spore germination
FOC14_RS04630	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC14_RS04635	COG3813	Protein conserved in bacteria
FOC14_RS04640	COG2706	6-phosphogluconolactonase activity
FOC14_RS04645	COG1070	Carbohydrate kinase
FOC14_RS04655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC14_RS04660	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC14_RS04670	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC14_RS04675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC14_RS04680	COG0604	alcohol dehydrogenase
FOC14_RS04685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC14_RS04700	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS04725	COG0656	L-ascorbic acid biosynthetic process
FOC14_RS04730	COG2814	Major facilitator Superfamily
FOC14_RS04745	COG0346	lactoylglutathione lyase activity
FOC14_RS04750	COG0814	amino acid
FOC14_RS04775	COG1393	Belongs to the ArsC family
FOC14_RS04780	COG1733	regulation of RNA biosynthetic process
FOC14_RS04785	COG2188	Transcriptional regulator
FOC14_RS04795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC14_RS04800	COG1733	regulation of RNA biosynthetic process
FOC14_RS04805	COG1733	regulation of RNA biosynthetic process
FOC14_RS04820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS04840	COG0384	phenazine biosynthesis protein PhzF
FOC14_RS04850	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS04860	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS04870	COG1733	regulation of RNA biosynthetic process
FOC14_RS04905	COG1191	sigma factor activity
FOC14_RS04920	COG1309	transcriptional regulator
FOC14_RS04940	COG3152	Membrane
FOC14_RS04965	COG1151	hydroxylamine reductase activity
FOC14_RS04975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS04980	COG3757	hydrolase, family 25
FOC14_RS04980	COG3409	Peptidoglycan-binding domain 1 protein
FOC14_RS05015	COG2072	flavoprotein involved in K transport
FOC14_RS05055	COG1113	amino acid transport
FOC14_RS05060	COG2814	Major facilitator Superfamily
FOC14_RS05090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC14_RS05095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC14_RS05115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS05120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS05125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS05130	COG3739	integral membrane protein
FOC14_RS05135	COG0384	phenazine biosynthesis protein PhzF
FOC14_RS05165	COG0583	DNA-binding transcription factor activity
FOC14_RS05185	COG1193	negative regulation of DNA recombination
FOC14_RS05205	COG1164	Oligoendopeptidase f
FOC14_RS05210	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC14_RS05240	COG0584	glycerophosphoryl diester phosphodiesterase
FOC14_RS05265	COG0640	Transcriptional regulator
FOC14_RS05270	COG0604	alcohol dehydrogenase
FOC14_RS05290	COG2808	Putative FMN-binding domain
FOC14_RS05295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC14_RS05305	COG0385	Bile acid
FOC14_RS05310	COG0277	FAD linked oxidase domain protein
FOC14_RS05340	COG1216	Glycosyl transferase, family 2
FOC14_RS05345	COG1024	Enoyl-CoA hydratase
FOC14_RS05355	COG1285	pathogenesis
FOC14_RS05370	COG2514	catechol 2,3-dioxygenase activity
FOC14_RS05375	COG2720	vancomycin resistance protein
FOC14_RS05400	COG1278	Cold shock
FOC14_RS05410	COG0716	FMN binding
FOC14_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS05450	COG0165	Argininosuccinate lyase
FOC14_RS05465	COG4145	pantothenate transmembrane transporter activity
FOC14_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS05480	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS05490	COG1657	PFAM Prenyltransferase squalene oxidase
FOC14_RS05495	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC14_RS05500	COG2962	Rard protein
FOC14_RS05505	COG3326	Membrane
FOC14_RS05520	COG0489	protein tyrosine kinase activity
FOC14_RS05530	COG0314	molybdopterin synthase activity
FOC14_RS05535	COG0303	'Molybdopterin
FOC14_RS05540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC14_RS05545	COG2116	formate transmembrane transporter activity
FOC14_RS05555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC14_RS05560	COG5609	conserved protein (DUF2294)
FOC14_RS05565	COG2427	Protein of unknown function (DUF1641)
FOC14_RS05570	COG3383	formate dehydrogenase (NAD+) activity
FOC14_RS05575	COG0697	spore germination
FOC14_RS05615	COG2226	methyltransferase
FOC14_RS05620	COG4166	transmembrane transport
FOC14_RS05625	COG4166	transmembrane transport
FOC14_RS05630	COG4166	transmembrane transport
FOC14_RS05640	COG1316	TRANSCRIPTIONal
FOC14_RS05650	COG1595	DNA-templated transcription, initiation
FOC14_RS05665	COG1131	(ABC) transporter
FOC14_RS05675	COG0673	inositol 2-dehydrogenase activity
FOC14_RS05680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC14_RS05685	COG0187	DNA topoisomerase II activity
FOC14_RS05690	COG1832	CoA-binding protein
FOC14_RS05695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC14_RS05700	COG0745	RESPONSE REGULATOR receiver
FOC14_RS05715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOC14_RS05720	COG4841	protein insertion into membrane
FOC14_RS05725	COG0824	Thioesterase
FOC14_RS05755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC14_RS05765	COG2274	protein secretion by the type I secretion system
FOC14_RS05770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC14_RS05780	COG0726	polysaccharide deacetylase
FOC14_RS05810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC14_RS05825	COG0183	Belongs to the thiolase family
FOC14_RS05830	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS05835	COG1268	BioY protein
FOC14_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS05890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS05900	COG5002	protein histidine kinase activity
FOC14_RS05905	COG0400	carboxylic ester hydrolase activity
FOC14_RS05910	COG0346	lactoylglutathione lyase activity
FOC14_RS05915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC14_RS05920	COG0069	glutamate synthase activity
FOC14_RS05925	COG1902	pentaerythritol trinitrate reductase activity
FOC14_RS05930	COG1329	Transcriptional regulator
FOC14_RS05935	COG0010	Belongs to the arginase family
FOC14_RS05960	COG2226	methyltransferase
FOC14_RS06015	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC14_RS06020	COG0785	Cytochrome C biogenesis protein
FOC14_RS06030	COG0583	DNA-binding transcription factor activity
FOC14_RS06035	COG1380	Effector of murein hydrolase LrgA
FOC14_RS06040	COG1346	cytolysis
FOC14_RS06065	COG3409	Peptidoglycan-binding domain 1 protein
FOC14_RS06065	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS06080	COG1132	(ABC) transporter
FOC14_RS06085	COG1132	(ABC) transporter
FOC14_RS06115	COG3639	organic phosphonate transmembrane transporter activity
FOC14_RS06120	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC14_RS06140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC14_RS06160	COG1695	Transcriptional regulator
FOC14_RS06190	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS06190	COG3409	Peptidoglycan-binding domain 1 protein
FOC14_RS06190	COG1388	LysM domain
FOC14_RS06195	COG4824	toxin secretion phage lysis holin
FOC14_RS06340	COG1595	DNA-templated transcription, initiation
FOC14_RS06380	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FOC14_RS06460	COG1396	sequence-specific DNA binding
FOC14_RS06480	COG0174	glutamine synthetase
FOC14_RS06485	COG0789	Transcriptional regulator
FOC14_RS06490	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC14_RS06500	COG2860	membrane
FOC14_RS06510	COG0464	growth
FOC14_RS06540	COG1388	LysM domain
FOC14_RS06540	COG3584	3D domain protein
FOC14_RS06545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC14_RS06545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC14_RS06545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC14_RS06550	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC14_RS06555	COG1349	DNA-binding transcription factor activity
FOC14_RS06565	COG2322	membrane
FOC14_RS06575	COG1113	amino acid transport
FOC14_RS06585	COG1408	metallophosphoesterase
FOC14_RS06590	COG2116	formate transmembrane transporter activity
FOC14_RS06600	COG2217	Heavy metal translocating P-type atpase
FOC14_RS06605	COG2608	mercury ion transmembrane transporter activity
FOC14_RS06610	COG1937	Protein conserved in bacteria
FOC14_RS06620	COG2819	hydrolase of the alpha beta superfamily
FOC14_RS06625	COG1120	ATPase activity
FOC14_RS06630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS06635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS06645	COG0708	Exodeoxyribonuclease III
FOC14_RS06650	COG2169	Transcriptional regulator
FOC14_RS06655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC14_RS06660	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC14_RS06670	COG2364	Membrane
FOC14_RS06685	COG2267	carboxylic ester hydrolase activity
FOC14_RS06690	COG0346	lactoylglutathione lyase activity
FOC14_RS06695	COG3300	MHYT domain
FOC14_RS06695	COG5001	Diguanylate cyclase
FOC14_RS06710	COG1346	cytolysis
FOC14_RS06715	COG1380	Effector of murein hydrolase LrgA
FOC14_RS06720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS06725	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC14_RS06725	COG0596	Alpha beta hydrolase
FOC14_RS06730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC14_RS06750	COG1404	Belongs to the peptidase S8 family
FOC14_RS06755	COG3773	Cell wall hydrolase
FOC14_RS06760	COG0562	UDP-galactopyranose mutase
FOC14_RS06765	COG1368	sulfuric ester hydrolase activity
FOC14_RS06770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC14_RS06780	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC14_RS06825	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC14_RS06830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC14_RS06835	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC14_RS06840	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC14_RS06840	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC14_RS06850	COG2359	stage V sporulation protein S
FOC14_RS06855	COG1692	metallophosphoesterase
FOC14_RS06880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC14_RS06885	COG1426	Protein conserved in bacteria
FOC14_RS06900	COG0300	oxidoreductase activity
FOC14_RS06905	COG0612	Peptidase, M16
FOC14_RS06910	COG0612	Peptidase, M16
FOC14_RS06935	COG2188	Transcriptional regulator
FOC14_RS06940	COG1674	ftsk spoiiie
FOC14_RS06950	COG0740	serine-type endopeptidase activity
FOC14_RS06955	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC14_RS06965	COG0527	aspartate kinase activity
FOC14_RS06970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC14_RS06975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC14_RS06980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC14_RS06985	COG1873	PFAM PRC-barrel domain
FOC14_RS06990	COG0612	Peptidase, M16
FOC14_RS06995	COG0726	polysaccharide deacetylase
FOC14_RS07010	COG0196	riboflavin kinase activity
FOC14_RS07015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC14_RS07025	COG1550	Protein conserved in bacteria
FOC14_RS07035	COG1358	cellular component organization or biogenesis
FOC14_RS07040	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC14_RS07045	COG0195	Participates in both transcription termination and antitermination
FOC14_RS07065	COG0750	zinc metalloprotease
FOC14_RS07070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC14_RS07075	COG4589	Belongs to the CDS family
FOC14_RS07080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC14_RS07090	COG0528	UMP kinase activity
FOC14_RS07120	COG4974	Belongs to the 'phage' integrase family
FOC14_RS07130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC14_RS07140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC14_RS07180	COG1837	Belongs to the UPF0109 family
FOC14_RS07190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC14_RS07200	COG0552	protein localization to endoplasmic reticulum
FOC14_RS07205	COG1196	nuclear chromosome segregation
FOC14_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS07225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC14_RS07240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC14_RS07245	COG1461	Dihydroxyacetone kinase
FOC14_RS07250	COG1302	Protein conserved in bacteria
FOC14_RS07265	COG1564	THIamine pyrophosphokinase
FOC14_RS07270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC14_RS07275	COG1162	GTPase activity
FOC14_RS07280	COG0515	serine threonine protein kinase
FOC14_RS07280	COG2815	serine threonine protein kinase
FOC14_RS07285	COG0631	protein serine/threonine phosphatase activity
FOC14_RS07295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC14_RS07295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC14_RS07305	COG0242	peptide deformylase activity
FOC14_RS07310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC14_RS07315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC14_RS07325	COG0194	GDP metabolic process
FOC14_RS07335	COG1561	YicC-like family, N-terminal region
FOC14_RS07340	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC14_RS07350	COG0006	proline dipeptidase activity
FOC14_RS07365	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC14_RS07405	COG0505	Belongs to the CarA family
FOC14_RS07430	COG0564	pseudouridine synthase activity
FOC14_RS07450	COG3599	regulation of cell shape
FOC14_RS07455	COG2302	S4 RNA-binding domain
FOC14_RS07460	COG0762	integral membrane protein
FOC14_RS07470	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC14_RS07480	COG1873	PFAM PRC-barrel domain
FOC14_RS07485	COG1191	sigma factor activity
FOC14_RS07490	COG1191	sigma factor activity
FOC14_RS07500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC14_RS07505	COG0849	cell division
FOC14_RS07510	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC14_RS07515	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC14_RS07520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC14_RS07525	COG0772	Belongs to the SEDS family
FOC14_RS07540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC14_RS07545	COG0768	penicillin binding
FOC14_RS07555	COG4839	cell division protein FtsL
FOC14_RS07570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC14_RS07595	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC14_RS07645	COG4824	toxin secretion phage lysis holin
FOC14_RS07735	COG4626	Terminase
FOC14_RS07735	COG1802	Transcriptional regulator
FOC14_RS07760	COG0582	viral genome integration into host DNA
FOC14_RS07835	COG1191	sigma factor activity
FOC14_RS07860	COG1484	DNA-dependent DNA replication
FOC14_RS07880	COG1396	sequence-specific DNA binding
FOC14_RS07890	COG1396	sequence-specific DNA binding
FOC14_RS07900	COG0582	viral genome integration into host DNA
FOC14_RS07910	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC14_RS07915	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC14_RS07920	COG3314	Sporulation integral membrane protein YlbJ
FOC14_RS07930	COG0742	ribosomal rna small subunit methyltransferase
FOC14_RS07945	COG3679	Belongs to the UPF0342 family
FOC14_RS07950	COG0406	alpha-ribazole phosphatase activity
FOC14_RS07965	COG2340	Cysteine-rich secretory protein family
FOC14_RS07980	COG3336	cytochrome c oxidase
FOC14_RS08015	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC14_RS08020	COG0772	Belongs to the SEDS family
FOC14_RS08025	COG4838	Belongs to the UPF0358 family
FOC14_RS08030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC14_RS08035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC14_RS08045	COG4896	Protein conserved in bacteria
FOC14_RS08070	COG0483	inositol monophosphate 1-phosphatase activity
FOC14_RS08090	COG1982	Orn Lys Arg decarboxylase major
FOC14_RS08135	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC14_RS08140	COG0022	dehydrogenase e1 component
FOC14_RS08145	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC14_RS08155	COG0242	peptide deformylase activity
FOC14_RS08170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC14_RS08175	COG0569	domain protein
FOC14_RS08195	COG0583	DNA-binding transcription factor activity
FOC14_RS08200	COG0517	IMP dehydrogenase activity
FOC14_RS08210	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC14_RS08215	COG4703	Protein of unknown function (DUF1797)
FOC14_RS08230	COG2200	EAL domain
FOC14_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS08240	COG1408	metallophosphoesterase
FOC14_RS08250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC14_RS08285	COG2814	Major facilitator Superfamily
FOC14_RS08305	COG3209	COG3209 Rhs family protein
FOC14_RS08315	COG2205	protein histidine kinase activity
FOC14_RS08325	COG0436	Aminotransferase
FOC14_RS08330	COG1609	Transcriptional regulator
FOC14_RS08335	COG3833	ABC-type maltose transport systems, permease component
FOC14_RS08340	COG1175	transmembrane transport
FOC14_RS08345	COG2182	Extracellular solute-binding protein
FOC14_RS08355	COG0366	Alpha amylase catalytic
FOC14_RS08360	COG3842	ATPase activity
FOC14_RS08400	COG0183	Belongs to the thiolase family
FOC14_RS08440	COG1695	Transcriptional regulator
FOC14_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS08465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC14_RS08470	COG0436	Aminotransferase
FOC14_RS08490	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FOC14_RS08510	COG3706	GGDEF domain
FOC14_RS08515	COG0778	Nitroreductase
FOC14_RS08540	COG1263	PTS System
FOC14_RS08540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC14_RS08540	COG2190	(PTS) system
FOC14_RS08545	COG3711	transcriptional antiterminator
FOC14_RS08565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC14_RS08590	COG1547	Domain of unknown function (DUF309)
FOC14_RS08595	COG0456	acetyltransferase
FOC14_RS08600	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC14_RS08605	COG4086	secreted protein
FOC14_RS08610	COG0561	phosphatase activity
FOC14_RS08615	COG0697	spore germination
FOC14_RS08630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC14_RS08655	COG0733	neurotransmitter:sodium symporter activity
FOC14_RS08675	COG1686	Belongs to the peptidase S11 family
FOC14_RS08680	COG1725	Transcriptional regulator
FOC14_RS08685	COG1131	(ABC) transporter
FOC14_RS08700	COG1846	Transcriptional regulator
FOC14_RS08715	COG0598	Magnesium transport protein CorA
FOC14_RS08740	COG4974	Belongs to the 'phage' integrase family
FOC14_RS08750	COG0735	belongs to the Fur family
FOC14_RS08755	COG1300	Membrane
FOC14_RS08775	COG0667	Aldo Keto reductase
FOC14_RS08780	COG0656	L-ascorbic acid biosynthetic process
FOC14_RS08785	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC14_RS08785	COG0456	acetyltransferase
FOC14_RS08795	COG1525	nuclease
FOC14_RS08795	COG4085	toxin activity
FOC14_RS08795	COG0737	Belongs to the 5'-nucleotidase family
FOC14_RS08805	COG0596	Alpha beta hydrolase
FOC14_RS08810	COG2056	Na+-H+ antiporter family
FOC14_RS08815	COG1609	Transcriptional regulator
FOC14_RS08820	COG0456	acetyltransferase
FOC14_RS08825	COG1073	alpha beta
FOC14_RS08840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC14_RS08840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC14_RS08845	COG0307	riboflavin synthase, alpha
FOC14_RS08865	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC14_RS08870	COG4106	trans-aconitate 2-methyltransferase activity
FOC14_RS08875	COG2226	methyltransferase
FOC14_RS08875	COG1073	alpha beta
FOC14_RS08880	COG0156	8-amino-7-oxononanoate synthase activity
FOC14_RS08890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC14_RS08905	COG0737	Belongs to the 5'-nucleotidase family
FOC14_RS08915	COG1522	sequence-specific DNA binding
FOC14_RS08935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC14_RS08945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC14_RS08960	COG0300	oxidoreductase activity
FOC14_RS08970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC14_RS08975	COG1760	l-serine dehydratase
FOC14_RS08980	COG1760	l-serine dehydratase
FOC14_RS09000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC14_RS09010	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC14_RS09015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS09030	COG1376	ErfK ybiS ycfS ynhG family protein
FOC14_RS09035	COG4129	membrane
FOC14_RS09040	COG1126	abc transporter atp-binding protein
FOC14_RS09045	COG0765	amino acid transport
FOC14_RS09050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC14_RS09070	COG0772	Belongs to the SEDS family
FOC14_RS09075	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC14_RS09080	COG0022	dehydrogenase e1 component
FOC14_RS09085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC14_RS09090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC14_RS09100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC14_RS09105	COG0280	phosphate acetyltransferase
FOC14_RS09110	COG3290	protein histidine kinase activity
FOC14_RS09110	COG3829	transcription factor binding
FOC14_RS09120	COG0584	glycerophosphoryl diester phosphodiesterase
FOC14_RS09125	COG3093	addiction module antidote protein HigA
FOC14_RS09135	COG0745	RESPONSE REGULATOR receiver
FOC14_RS09140	COG0750	zinc metalloprotease
FOC14_RS09145	COG0497	DNA recombination
FOC14_RS09155	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC14_RS09165	COG0142	geranyltranstransferase activity
FOC14_RS09190	COG1302	Protein conserved in bacteria
FOC14_RS09195	COG0439	Biotin carboxylase
FOC14_RS09200	COG0511	ligase activity, forming carbon-carbon bonds
FOC14_RS09245	COG3854	ATPases associated with a variety of cellular activities
FOC14_RS09270	COG0006	proline dipeptidase activity
FOC14_RS09285	COG3872	metal-dependent enzyme
FOC14_RS09295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC14_RS09315	COG0095	Lipoate-protein ligase
FOC14_RS09320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC14_RS09325	COG1609	Transcriptional regulator
FOC14_RS09335	COG2076	Multidrug Resistance protein
FOC14_RS09340	COG2076	Multidrug Resistance protein
FOC14_RS09375	COG1131	(ABC) transporter
FOC14_RS09380	COG1725	Transcriptional regulator
FOC14_RS09410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC14_RS09465	COG4970	Tfp pilus assembly protein FimT
FOC14_RS09475	COG1459	type II secretion system
FOC14_RS09480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC14_RS09530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC14_RS09535	COG1410	methionine synthase
FOC14_RS09535	COG0646	methionine synthase
FOC14_RS09540	COG0646	methionine synthase
FOC14_RS09540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC14_RS09545	COG0626	cystathionine gamma-synthase activity
FOC14_RS09550	COG0626	cystathionine gamma-synthase activity
FOC14_RS09570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS09580	COG1940	carbohydrate kinase activity
FOC14_RS09585	COG4483	Protein conserved in bacteria
FOC14_RS09590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC14_RS09600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC14_RS09605	COG0704	Plays a role in the regulation of phosphate uptake
FOC14_RS09610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC14_RS09615	COG0581	inorganic phosphate transmembrane transporter activity
FOC14_RS09620	COG0573	inorganic phosphate transmembrane transporter activity
FOC14_RS09625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC14_RS09635	COG0477	Major facilitator Superfamily
FOC14_RS09640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC14_RS09665	COG0735	belongs to the Fur family
FOC14_RS09670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC14_RS09675	COG1121	(ABC) transporter
FOC14_RS09680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS09710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC14_RS09715	COG2384	SAM-dependent methyltransferase
FOC14_RS09720	COG2010	Cytochrome c
FOC14_RS09725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC14_RS09730	COG0358	DNA primase activity
FOC14_RS09740	COG0517	IMP dehydrogenase activity
FOC14_RS09755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC14_RS09760	COG0295	cytidine deaminase activity
FOC14_RS09765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC14_RS09775	COG1480	7TM receptor with intracellular HD hydrolase
FOC14_RS09780	COG1702	phosphate starvation-inducible protein PhoH
FOC14_RS09795	COG1610	YqeY-like protein
FOC14_RS09805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC14_RS09810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC14_RS09830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC14_RS09840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC14_RS09845	COG1733	regulation of RNA biosynthetic process
FOC14_RS09870	COG1466	dna polymerase III delta subunit
FOC14_RS09880	COG2333	competence protein COMEC
FOC14_RS09880	COG0658	competence protein
FOC14_RS09885	COG2131	deaminase
FOC14_RS09890	COG1596	polysaccharide export
FOC14_RS09890	COG1555	photosystem II stabilization
FOC14_RS09895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC14_RS09900	COG2226	methyltransferase
FOC14_RS09905	COG0799	negative regulation of ribosome biogenesis
FOC14_RS09910	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC14_RS09920	COG1534	Rna-binding protein
FOC14_RS09930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC14_RS09935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC14_RS09950	COG1191	sigma factor activity
FOC14_RS09960	COG1595	DNA-templated transcription, initiation
FOC14_RS09970	COG0778	Nitroreductase
FOC14_RS09975	COG2357	RelA SpoT domain protein
FOC14_RS09985	COG1785	Belongs to the alkaline phosphatase family
FOC14_RS09995	COG2267	carboxylic ester hydrolase activity
FOC14_RS10030	COG1404	Belongs to the peptidase S8 family
FOC14_RS10035	COG3186	Phenylalanine-4-hydroxylase
FOC14_RS10050	COG2259	Doxx family
FOC14_RS10090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS10100	COG1454	alcohol dehydrogenase
FOC14_RS10100	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS10105	COG0626	cystathionine gamma-synthase activity
FOC14_RS10110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC14_RS10135	COG0768	penicillin binding
FOC14_RS10165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC14_RS10185	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC14_RS10195	COG0628	permease
FOC14_RS10215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC14_RS10225	COG0482	sulfurtransferase activity
FOC14_RS10230	COG1104	cysteine desulfurase activity
FOC14_RS10235	COG1959	2 iron, 2 sulfur cluster binding
FOC14_RS10240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC14_RS10250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC14_RS10260	COG0124	histidyl-tRNA synthetase
FOC14_RS10270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC14_RS10280	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC14_RS10280	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC14_RS10285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC14_RS10290	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC14_RS10290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC14_RS10300	COG2244	polysaccharide biosynthetic process
FOC14_RS10305	COG2323	membrane
FOC14_RS10315	COG1862	Preprotein translocase
FOC14_RS10345	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC14_RS10355	COG0697	spore germination
FOC14_RS10360	COG0697	spore germination
FOC14_RS10365	COG0640	Transcriptional regulator
FOC14_RS10390	COG0157	Belongs to the NadC ModD family
FOC14_RS10395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC14_RS10400	COG1104	cysteine desulfurase activity
FOC14_RS10405	COG1827	regulation of RNA biosynthetic process
FOC14_RS10410	COG2258	MOSC domain
FOC14_RS10415	COG0077	Prephenate dehydratase
FOC14_RS10420	COG0577	efflux transmembrane transporter activity
FOC14_RS10425	COG0577	efflux transmembrane transporter activity
FOC14_RS10430	COG1136	(ABC) transporter
FOC14_RS10440	COG0745	RESPONSE REGULATOR receiver
FOC14_RS10445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC14_RS10460	COG2868	ribosomal protein
FOC14_RS10470	COG1530	ribonuclease E activity
FOC14_RS10475	COG1994	Peptidase M50
FOC14_RS10480	COG0739	heme binding
FOC14_RS10485	COG2894	cell division
FOC14_RS10500	COG1792	Involved in formation and maintenance of cell shape
FOC14_RS10505	COG1077	Cell shape determining protein MreB Mrl
FOC14_RS10525	COG0285	dihydrofolate synthase activity
FOC14_RS10530	COG0525	valine-tRNA ligase activity
FOC14_RS10540	COG1388	LysM domain
FOC14_RS10550	COG0113	porphobilinogen synthase activity
FOC14_RS10555	COG1587	Uroporphyrinogen-III synthase
FOC14_RS10565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC14_RS10575	COG1846	Transcriptional regulator
FOC14_RS10580	COG1764	response to oxidative stress
FOC14_RS10595	COG1067	ATP-dependent peptidase activity
FOC14_RS10595	COG0470	DNA polymerase III
FOC14_RS10640	COG0622	Phosphoesterase
FOC14_RS10645	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC14_RS10655	COG5401	PFAM Sporulation and spore germination
FOC14_RS10675	COG1309	transcriptional regulator
FOC14_RS10690	COG2197	response regulator
FOC14_RS10695	COG2233	PERMEase
FOC14_RS10705	COG0402	S-adenosylhomocysteine deaminase activity
FOC14_RS10710	COG0402	S-adenosylhomocysteine deaminase activity
FOC14_RS10730	COG0444	Belongs to the ABC transporter superfamily
FOC14_RS10735	COG4608	Belongs to the ABC transporter superfamily
FOC14_RS10745	COG3279	Response regulator of the LytR AlgR family
FOC14_RS10760	COG1983	PspC domain protein
FOC14_RS10765	COG1396	sequence-specific DNA binding
FOC14_RS10770	COG0697	spore germination
FOC14_RS10780	COG1959	2 iron, 2 sulfur cluster binding
FOC14_RS10785	COG1668	transmembrane transport
FOC14_RS10790	COG4152	abc transporter atp-binding protein
FOC14_RS10795	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC14_RS10805	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC14_RS10810	COG1876	peptidase activity
FOC14_RS10815	COG0824	Thioesterase
FOC14_RS10820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC14_RS10825	COG1053	succinate dehydrogenase
FOC14_RS10830	COG2009	succinate dehydrogenase
FOC14_RS10835	COG1719	4-vinyl reductase, 4VR
FOC14_RS10845	COG3118	belongs to the thioredoxin family
FOC14_RS10850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC14_RS10855	COG2086	electron transfer activity
FOC14_RS10860	COG1024	Enoyl-CoA hydratase
FOC14_RS10865	COG1309	transcriptional regulator
FOC14_RS10870	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS10890	COG2318	DinB family
FOC14_RS10915	COG1131	(ABC) transporter
FOC14_RS10920	COG2205	protein histidine kinase activity
FOC14_RS10925	COG0745	RESPONSE REGULATOR receiver
FOC14_RS10930	COG4895	conserved protein (DUF2196)
FOC14_RS10935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC14_RS10950	COG4509	Sortase family
FOC14_RS10955	COG1120	ATPase activity
FOC14_RS10970	COG5386	Cell surface protein
FOC14_RS10980	COG5386	Cell surface protein
FOC14_RS10985	COG1114	Component of the transport system for branched-chain amino acids
FOC14_RS10990	COG1187	pseudouridine synthase activity
FOC14_RS11000	COG1796	DNA polymerase
FOC14_RS11000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC14_RS11005	COG1286	toxin biosynthetic process
FOC14_RS11035	COG0017	Asparaginyl-tRNA synthetase
FOC14_RS11040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC14_RS11040	COG0072	phenylalanine-tRNA ligase activity
FOC14_RS11050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC14_RS11060	COG1418	mRNA catabolic process
FOC14_RS11085	COG2814	Major facilitator Superfamily
FOC14_RS11090	COG1566	PFAM secretion protein HlyD family protein
FOC14_RS11095	COG1309	transcriptional regulator
FOC14_RS11100	COG1363	Peptidase, m42
FOC14_RS11120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC14_RS11125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC14_RS11135	COG1484	DNA-dependent DNA replication
FOC14_RS11140	COG3611	Membrane attachment protein
FOC14_RS11150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC14_RS11160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC14_RS11165	COG0237	dephospho-CoA kinase activity
FOC14_RS11170	COG1971	Probably functions as a manganese efflux pump
FOC14_RS11175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOC14_RS11180	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC14_RS11180	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC14_RS11185	COG5002	protein histidine kinase activity
FOC14_RS11190	COG0745	RESPONSE REGULATOR receiver
FOC14_RS11205	COG0538	isocitrate dehydrogenase activity
FOC14_RS11210	COG0372	Belongs to the citrate synthase family
FOC14_RS11220	COG0628	permease
FOC14_RS11225	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC14_RS11250	COG1725	Transcriptional regulator
FOC14_RS11255	COG0281	malic enzyme
FOC14_RS11260	COG0587	DNA-directed DNA polymerase activity
FOC14_RS11275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC14_RS11295	COG4109	DRTGG domain
FOC14_RS11310	COG0006	proline dipeptidase activity
FOC14_RS11345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS11350	COG0662	Cupin 2, conserved barrel domain protein
FOC14_RS11360	COG1476	TRANSCRIPTIONal
FOC14_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS11380	COG0589	response to stress
FOC14_RS11420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS11440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC14_RS11445	COG0827	DNA restriction-modification system
FOC14_RS11450	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC14_RS11455	COG3874	Sporulation protein YtfJ
FOC14_RS11465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC14_RS11470	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC14_RS11480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC14_RS11495	COG1104	cysteine desulfurase activity
FOC14_RS11505	COG0583	DNA-binding transcription factor activity
FOC14_RS11510	COG0697	spore germination
FOC14_RS11520	COG1956	GAF domain-containing protein
FOC14_RS11525	COG0626	cystathionine gamma-synthase activity
FOC14_RS11545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC14_RS11555	COG1595	DNA-templated transcription, initiation
FOC14_RS11570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC14_RS11575	COG0454	-acetyltransferase
FOC14_RS11580	COG0517	IMP dehydrogenase activity
FOC14_RS11585	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC14_RS11595	COG0745	RESPONSE REGULATOR receiver
FOC14_RS11605	COG0666	response to abiotic stimulus
FOC14_RS11640	COG1609	Transcriptional regulator
FOC14_RS11645	COG4851	CamS sex pheromone cAM373 precursor
FOC14_RS11650	COG3118	belongs to the thioredoxin family
FOC14_RS11660	COG2309	aminopeptidase activity
FOC14_RS11680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS11695	COG1674	ftsk spoiiie
FOC14_RS11705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC14_RS11710	COG4848	Belongs to the UPF0354 family
FOC14_RS11715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC14_RS11720	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC14_RS11725	COG1363	Peptidase, m42
FOC14_RS11735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS11750	COG0510	thiamine kinase activity
FOC14_RS11755	COG1523	belongs to the glycosyl hydrolase 13 family
FOC14_RS11770	COG1349	DNA-binding transcription factor activity
FOC14_RS11775	COG1187	pseudouridine synthase activity
FOC14_RS11780	COG2244	polysaccharide biosynthetic process
FOC14_RS11785	COG2081	HI0933 family
FOC14_RS11790	COG2814	Major facilitator Superfamily
FOC14_RS11800	COG3832	glyoxalase III activity
FOC14_RS11820	COG1329	Transcriptional regulator
FOC14_RS11830	COG4975	Glucose uptake
FOC14_RS11845	COG0314	molybdopterin synthase activity
FOC14_RS11850	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC14_RS11855	COG0303	'Molybdopterin
FOC14_RS11865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC14_RS11890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC14_RS11900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC14_RS11940	COG2814	Major facilitator Superfamily
FOC14_RS11945	COG0475	glutathione-regulated potassium exporter activity
FOC14_RS11950	COG0490	domain, Protein
FOC14_RS11955	COG0582	viral genome integration into host DNA
FOC14_RS11965	COG1136	(ABC) transporter
FOC14_RS11985	COG1242	4 iron, 4 sulfur cluster binding
FOC14_RS11990	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC14_RS11995	COG1131	(ABC) transporter
FOC14_RS12005	COG1794	racemase activity, acting on amino acids and derivatives
FOC14_RS12025	COG2267	carboxylic ester hydrolase activity
FOC14_RS12030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC14_RS12035	COG0671	phosphoesterase, PA-phosphatase related
FOC14_RS12040	COG0438	transferase activity, transferring glycosyl groups
FOC14_RS12050	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC14_RS12100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC14_RS12105	COG5002	protein histidine kinase activity
FOC14_RS12110	COG4191	Histidine kinase
FOC14_RS12115	COG2267	carboxylic ester hydrolase activity
FOC14_RS12135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC14_RS12140	COG1116	anion transmembrane transporter activity
FOC14_RS12145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC14_RS12170	COG0494	nUDIX hydrolase
FOC14_RS12200	COG0288	reversible hydration of carbon dioxide
FOC14_RS12205	COG1271	oxidase subunit
FOC14_RS12210	COG1294	oxidase, subunit
FOC14_RS12230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS12255	COG1842	Phage shock protein A
FOC14_RS12290	COG5002	protein histidine kinase activity
FOC14_RS12295	COG0745	RESPONSE REGULATOR receiver
FOC14_RS12325	COG1597	lipid kinase activity
FOC14_RS12360	COG0586	Pfam SNARE associated Golgi protein
FOC14_RS12370	COG0577	efflux transmembrane transporter activity
FOC14_RS12375	COG1136	(ABC) transporter
FOC14_RS12380	COG2207	Transcriptional regulator
FOC14_RS12380	COG3708	Transcriptional regulator
FOC14_RS12385	COG0745	RESPONSE REGULATOR receiver
FOC14_RS12390	COG2205	protein histidine kinase activity
FOC14_RS12400	COG0577	efflux transmembrane transporter activity
FOC14_RS12405	COG1136	(ABC) transporter
FOC14_RS12445	COG3964	amidohydrolase
FOC14_RS12475	COG4948	Mandelate Racemase Muconate Lactonizing
FOC14_RS12485	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC14_RS12490	COG0596	Alpha beta hydrolase
FOC14_RS12495	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC14_RS12500	COG1169	isochorismate synthase
FOC14_RS12505	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC14_RS12510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC14_RS12515	COG1278	Cold shock
FOC14_RS12530	COG0058	SHG alpha-glucan phosphorylase activity
FOC14_RS12535	COG0297	glycogen (starch) synthase activity
FOC14_RS12540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC14_RS12545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC14_RS12565	COG0039	L-malate dehydrogenase activity
FOC14_RS12660	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC14_RS12695	COG1285	pathogenesis
FOC14_RS12700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC14_RS12710	COG0166	Belongs to the GPI family
FOC14_RS12715	COG2155	Conserved Protein
FOC14_RS12720	COG1098	S1 RNA binding domain
FOC14_RS12725	COG0436	Aminotransferase
FOC14_RS12730	COG1522	sequence-specific DNA binding
FOC14_RS12735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC14_RS12740	COG2267	carboxylic ester hydrolase activity
FOC14_RS12750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC14_RS12765	COG5018	Exonuclease
FOC14_RS12770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC14_RS12785	COG0423	glycine-tRNA ligase activity
FOC14_RS12790	COG2050	protein possibly involved in aromatic compounds catabolism
FOC14_RS12800	COG1268	BioY protein
FOC14_RS12810	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC14_RS12815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC14_RS12830	COG3584	3D domain protein
FOC14_RS12845	COG1252	NADH dehydrogenase
FOC14_RS12860	COG3708	Transcriptional regulator
FOC14_RS12875	COG1683	Conserved Protein
FOC14_RS12895	COG0316	Belongs to the HesB IscA family
FOC14_RS12910	COG1252	NADH dehydrogenase
FOC14_RS12925	COG0390	transport system, permease component
FOC14_RS12930	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC14_RS12970	COG4837	Protein of unknown function (DUF1462)
FOC14_RS12975	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC14_RS12985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC14_RS12990	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC14_RS13000	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC14_RS13005	COG0647	UMP catabolic process
FOC14_RS13015	COG2445	Protein of unknown function DUF86
FOC14_RS13020	COG1494	fructose-1,6-bisphosphatase
FOC14_RS13035	COG4470	Protein conserved in bacteria
FOC14_RS13045	COG0789	Transcriptional regulator
FOC14_RS13050	COG4377	Putative membrane peptidase family (DUF2324)
FOC14_RS13075	COG0739	heme binding
FOC14_RS13085	COG3377	Domain of unknown function (DUF1805)
FOC14_RS13090	COG0737	Belongs to the 5'-nucleotidase family
FOC14_RS13095	COG1695	Transcriptional regulator
FOC14_RS13105	COG0719	Fe-S assembly protein
FOC14_RS13110	COG0822	iron-sulfur transferase activity
FOC14_RS13115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC14_RS13120	COG0719	Fe-S assembly protein
FOC14_RS13125	COG0396	ATPase activity
FOC14_RS13130	COG1464	Belongs to the NlpA lipoprotein family
FOC14_RS13135	COG1464	Belongs to the NlpA lipoprotein family
FOC14_RS13140	COG2011	ABC-type metal ion transport system permease component
FOC14_RS13145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC14_RS13155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC14_RS13160	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC14_RS13175	COG1393	Belongs to the ArsC family
FOC14_RS13220	COG0039	L-malate dehydrogenase activity
FOC14_RS13240	COG1309	transcriptional regulator
FOC14_RS13245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS13250	COG1960	acyl-CoA dehydrogenase activity
FOC14_RS13255	COG0183	Belongs to the thiolase family
FOC14_RS13260	COG1024	Enoyl-CoA hydratase
FOC14_RS13260	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC14_RS13270	COG1686	Belongs to the peptidase S11 family
FOC14_RS13285	COG0011	TIGRFAM Protein of
FOC14_RS13290	COG0840	transmembrane signaling receptor activity
FOC14_RS13305	COG2814	Major facilitator Superfamily
FOC14_RS13310	COG0531	amino acid
FOC14_RS13320	COG0706	membrane insertase activity
FOC14_RS13330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS13365	COG0586	Pfam SNARE associated Golgi protein
FOC14_RS13375	COG1376	ErfK ybiS ycfS ynhG family protein
FOC14_RS13380	COG0745	RESPONSE REGULATOR receiver
FOC14_RS13385	COG5002	protein histidine kinase activity
FOC14_RS13395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC14_RS13410	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC14_RS13415	COG3227	Zinc metalloprotease (Elastase)
FOC14_RS13420	COG1741	Belongs to the pirin family
FOC14_RS13435	COG0475	glutathione-regulated potassium exporter activity
FOC14_RS13440	COG0490	domain, Protein
FOC14_RS13445	COG1115	amino acid carrier protein
FOC14_RS13450	COG0783	Belongs to the Dps family
FOC14_RS13465	COG1611	Belongs to the LOG family
FOC14_RS13485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS13490	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS13495	COG1115	amino acid carrier protein
FOC14_RS13500	COG1115	amino acid carrier protein
FOC14_RS13505	COG2910	NAD(P)H-binding
FOC14_RS13520	COG0656	L-ascorbic acid biosynthetic process
FOC14_RS13525	COG2814	Major facilitator Superfamily
FOC14_RS13530	COG1733	regulation of RNA biosynthetic process
FOC14_RS13540	COG1252	NADH dehydrogenase
FOC14_RS13545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC14_RS13550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC14_RS13560	COG3290	protein histidine kinase activity
FOC14_RS13560	COG0840	transmembrane signaling receptor activity
FOC14_RS13570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC14_RS13575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC14_RS13590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS13595	COG3223	Belongs to the PsiE family
FOC14_RS13645	COG0557	exoribonuclease II activity
FOC14_RS13650	COG1647	Serine aminopeptidase, S33
FOC14_RS13655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC14_RS13660	COG1346	cytolysis
FOC14_RS13755	COG4695	Portal protein
FOC14_RS13780	COG4974	Belongs to the 'phage' integrase family
FOC14_RS13790	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC14_RS13795	COG0149	triose-phosphate isomerase activity
FOC14_RS13805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC14_RS13820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC14_RS13845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC14_RS13860	COG2323	membrane
FOC14_RS13865	COG0740	serine-type endopeptidase activity
FOC14_RS13870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC14_RS13880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC14_RS13890	COG1051	belongs to the nudix hydrolase family
FOC14_RS13900	COG0492	ferredoxin-NADP+ reductase activity
FOC14_RS13905	COG0457	Tetratricopeptide repeat
FOC14_RS13910	COG0110	maltose O-acetyltransferase activity
FOC14_RS13930	COG1950	PFAM Membrane protein of
FOC14_RS13940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC14_RS13945	COG0556	nucleotide-excision repair
FOC14_RS13965	COG0789	Transcriptional regulator
FOC14_RS13990	COG2855	membrane
FOC14_RS13995	COG0583	DNA-binding transcription factor activity
FOC14_RS14005	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC14_RS14020	COG1132	(ABC) transporter
FOC14_RS14025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC14_RS14030	COG3409	Peptidoglycan-binding domain 1 protein
FOC14_RS14030	COG0793	Belongs to the peptidase S41A family
FOC14_RS14035	COG2177	Part of the ABC transporter FtsEX involved in
FOC14_RS14040	COG2884	Cell division ATP-binding protein ftsE
FOC14_RS14060	COG0653	protein targeting
FOC14_RS14065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC14_RS14070	COG1278	Cold shock
FOC14_RS14075	COG1040	competence protein
FOC14_RS14080	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC14_RS14085	COG1388	LysM domain
FOC14_RS14085	COG0791	NLP P60 protein
FOC14_RS14090	COG1733	regulation of RNA biosynthetic process
FOC14_RS14095	COG1307	EDD domain protein, DegV family
FOC14_RS14100	COG1739	Uncharacterized protein family UPF0029
FOC14_RS14105	COG1316	TRANSCRIPTIONal
FOC14_RS14110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC14_RS14115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC14_RS14120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC14_RS14130	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC14_RS14130	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC14_RS14145	COG3394	polysaccharide catabolic process
FOC14_RS14150	COG1486	melibiose metabolic process
FOC14_RS14155	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC14_RS14160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC14_RS14170	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC14_RS14175	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC14_RS14180	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC14_RS14190	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC14_RS14195	COG1301	dicarboxylic acid transport
FOC14_RS14205	COG0346	lactoylglutathione lyase activity
FOC14_RS14210	COG1511	domain protein
FOC14_RS14215	COG0583	DNA-binding transcription factor activity
FOC14_RS14220	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC14_RS14235	COG1271	oxidase subunit
FOC14_RS14240	COG1294	oxidase, subunit
FOC14_RS14245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC14_RS14255	COG1620	l-lactate permease
FOC14_RS14265	COG2389	metal-binding protein
FOC14_RS14275	COG1368	sulfuric ester hydrolase activity
FOC14_RS14290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS14305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC14_RS14310	COG1388	LysM domain
FOC14_RS14310	COG3584	3D domain protein
FOC14_RS14335	COG4715	Zinc finger, swim domain protein
FOC14_RS14340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC14_RS14370	COG1191	sigma factor activity
FOC14_RS14380	COG0577	efflux transmembrane transporter activity
FOC14_RS14385	COG1136	(ABC) transporter
FOC14_RS14420	COG5002	protein histidine kinase activity
FOC14_RS14425	COG0745	RESPONSE REGULATOR receiver
FOC14_RS14430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC14_RS14445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC14_RS14450	COG1134	teichoic acid transport
FOC14_RS14455	COG1682	transport, permease protein
FOC14_RS14460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC14_RS14505	COG1609	Transcriptional regulator
FOC14_RS14520	COG0739	heme binding
FOC14_RS14540	COG2385	sporulation resulting in formation of a cellular spore
FOC14_RS14545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC14_RS14555	COG4836	Membrane
FOC14_RS14560	COG1007	ATP synthesis coupled electron transport
FOC14_RS14565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC14_RS14570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC14_RS14580	COG0839	Belongs to the complex I subunit 6 family
FOC14_RS14595	COG0649	NAD binding
FOC14_RS14600	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC14_RS14610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC14_RS14615	COG3300	MHYT domain
FOC14_RS14615	COG5001	Diguanylate cyclase
FOC14_RS14665	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC14_RS14700	COG0698	ribose 5-phosphate isomerase
FOC14_RS14710	COG2190	(PTS) system
FOC14_RS14715	COG2259	Doxx family
FOC14_RS14720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC14_RS14735	COG0009	L-threonylcarbamoyladenylate synthase
FOC14_RS14750	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC14_RS14755	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC14_RS14770	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC14_RS14775	COG1494	fructose-1,6-bisphosphatase
FOC14_RS14780	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC14_RS14795	COG4821	SIS domain
FOC14_RS14805	COG3343	RNA polymerase activity
FOC14_RS14815	COG1960	acyl-CoA dehydrogenase activity
FOC14_RS14820	COG1960	acyl-CoA dehydrogenase activity
FOC14_RS14825	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC14_RS14830	COG0183	Belongs to the thiolase family
FOC14_RS14835	COG2181	nitrate reductase activity
FOC14_RS14835	COG0247	lactate metabolic process
FOC14_RS14840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC14_RS14850	COG3300	MHYT domain
FOC14_RS14850	COG5001	Diguanylate cyclase
FOC14_RS14870	COG2197	response regulator
FOC14_RS14875	COG4585	Histidine kinase
FOC14_RS14880	COG0842	Transport permease protein
FOC14_RS14885	COG1131	(ABC) transporter
FOC14_RS14890	COG0024	Methionine aminopeptidase
FOC14_RS14900	COG2234	aminopeptidase activity
FOC14_RS14920	COG1595	DNA-templated transcription, initiation
FOC14_RS14925	COG0018	arginyl-trna synthetase
FOC14_RS14930	COG4506	Protein conserved in bacteria
FOC14_RS14935	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC14_RS14950	COG0010	Belongs to the arginase family
FOC14_RS14955	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC14_RS14960	COG2814	Major facilitator Superfamily
FOC14_RS14965	COG0789	Transcriptional regulator
FOC14_RS14970	COG0584	glycerophosphoryl diester phosphodiesterase
FOC14_RS14975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC14_RS14985	COG1994	Peptidase M50
FOC14_RS14995	COG1078	dGTPase activity
FOC14_RS15000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS15005	COG1120	ATPase activity
FOC14_RS15010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS15035	COG0095	Lipoate-protein ligase
FOC14_RS15040	COG0280	phosphate acetyltransferase
FOC14_RS15055	COG3773	Cell wall hydrolase
FOC14_RS15065	COG2363	Small membrane protein
FOC14_RS15080	COG2233	PERMEase
FOC14_RS15085	COG0561	phosphatase activity
FOC14_RS15090	COG2814	Major facilitator Superfamily
FOC14_RS15100	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC14_RS15105	COG1131	(ABC) transporter
FOC14_RS15110	COG2755	lipolytic protein G-D-S-L family
FOC14_RS15115	COG1609	Transcriptional regulator
FOC14_RS15125	COG0460	homoserine dehydrogenase
FOC14_RS15145	COG1011	Hydrolase
FOC14_RS15150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC14_RS15160	COG2197	response regulator
FOC14_RS15170	COG0351	phosphomethylpyrimidine kinase
FOC14_RS15175	COG3706	GGDEF domain
FOC14_RS15180	COG2879	small protein
FOC14_RS15185	COG1966	Carbon starvation protein
FOC14_RS15190	COG3279	Response regulator of the LytR AlgR family
FOC14_RS15195	COG0477	Major facilitator Superfamily
FOC14_RS15220	COG0840	transmembrane signaling receptor activity
FOC14_RS15230	COG1607	acyl-coa hydrolase
FOC14_RS15245	COG0488	(ABC) transporter
FOC14_RS15265	COG0463	Glycosyl transferase, family 2
FOC14_RS15270	COG1309	transcriptional regulator
FOC14_RS15275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC14_RS15280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC14_RS15280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC14_RS15285	COG0628	permease
FOC14_RS15300	COG3279	Response regulator of the LytR AlgR family
FOC14_RS15305	COG3275	phosphorelay sensor kinase activity
FOC14_RS15310	COG2814	Major facilitator Superfamily
FOC14_RS15315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC14_RS15320	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC14_RS15325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC14_RS15345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC14_RS15350	COG1272	protein, Hemolysin III
FOC14_RS15370	COG0516	GMP reductase activity
FOC14_RS15375	COG1164	Oligoendopeptidase f
FOC14_RS15395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC14_RS15400	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC14_RS15405	COG4853	Protein conserved in bacteria
FOC14_RS15410	COG4863	YycH protein
FOC14_RS15415	COG5002	protein histidine kinase activity
FOC14_RS15420	COG0745	RESPONSE REGULATOR receiver
FOC14_RS15450	COG0305	Participates in initiation and elongation during chromosome replication
FOC14_RS15460	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC14_RS15465	COG4241	membrane
FOC14_RS15475	COG0629	single-stranded DNA binding
FOC14_RS15485	COG0012	GTP binding
FOC14_RS15490	COG4481	Protein conserved in bacteria
FOC14_RS15495	COG0668	transmembrane transport
FOC14_RS15505	COG1475	DNA binding
FOC14_RS15510	COG1192	Involved in chromosome partitioning
FOC14_RS15530	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC14_RS15535	COG1847	R3H domain protein
FOC14_RS15540	COG0706	membrane insertase activity
FOC14_RS15560	COG0592	DNA-directed DNA polymerase activity
FOC14_RS15565	COG2501	S4 domain
FOC14_RS15575	COG0187	DNA topoisomerase II activity
FOC14_RS15580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC14_RS15615	COG0516	GMP reductase activity
FOC14_RS15615	COG0517	IMP dehydrogenase activity
FOC14_RS15620	COG1686	Belongs to the peptidase S11 family
FOC14_RS15650	COG1428	Deoxynucleoside kinase
FOC14_RS15655	COG1428	Deoxynucleoside kinase
FOC14_RS15660	COG1335	isochorismatase
FOC14_RS15665	COG0590	tRNA wobble adenosine to inosine editing
FOC14_RS15675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC14_RS15730	COG1982	Orn Lys Arg decarboxylase major
FOC14_RS15740	COG0470	DNA polymerase III
FOC14_RS15745	COG1774	PSP1 C-terminal conserved region
FOC14_RS15755	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC14_RS15765	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC14_RS15770	COG2002	toxin-antitoxin pair type II binding
FOC14_RS15775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC14_RS15775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC14_RS15780	COG0084	hydrolase, TatD family'
FOC14_RS15785	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC14_RS15800	COG4466	Protein conserved in bacteria
FOC14_RS15815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC14_RS15820	COG0251	oxidation-reduction process
FOC14_RS15835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC14_RS15840	COG0193	aminoacyl-tRNA hydrolase activity
FOC14_RS15850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC14_RS15855	COG2002	toxin-antitoxin pair type II binding
FOC14_RS15860	COG2244	polysaccharide biosynthetic process
FOC14_RS15865	COG3956	TIGRFAM MazG family protein
FOC14_RS15870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC14_RS15890	COG1098	S1 RNA binding domain
FOC14_RS15905	COG2208	phosphoserine phosphatase activity
FOC14_RS15910	COG0037	tRNA processing
FOC14_RS15920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC14_RS15935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC14_RS15940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC14_RS15945	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC14_RS15950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC14_RS15955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC14_RS15960	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC14_RS15965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC14_RS15970	COG1396	sequence-specific DNA binding
FOC14_RS15975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC14_RS16005	COG3880	PFAM UvrB UvrC protein
FOC14_RS16015	COG0542	response to heat
FOC14_RS16020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC14_RS16030	COG4956	integral membrane protein (PIN domain superfamily)
FOC14_RS16050	COG1045	serine acetyltransferase
FOC14_RS16065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC14_RS16070	COG3688	RNA-binding protein containing a PIN domain
FOC14_RS16080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC14_RS16085	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC14_RS16090	COG0250	Participates in transcription elongation, termination and antitermination
FOC14_RS16115	COG2813	Specifically methylates the guanine in position
FOC14_RS16125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC14_RS16130	COG1358	cellular component organization or biogenesis
FOC14_RS16235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC14_RS16260	COG0201	protein transport
FOC14_RS16270	COG0024	Methionine aminopeptidase
FOC14_RS16280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC14_RS16310	COG1122	ATPase activity
FOC14_RS16315	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC14_RS16320	COG0101	tRNA pseudouridine synthase activity
FOC14_RS16340	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS16345	COG0489	protein tyrosine kinase activity
FOC14_RS16355	COG2194	sulfuric ester hydrolase activity
FOC14_RS16360	COG0726	polysaccharide deacetylase
FOC14_RS16440	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC14_RS16445	COG4856	YbbR-like protein
FOC14_RS16460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC14_RS16465	COG0596	Alpha beta hydrolase
FOC14_RS16485	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC14_RS16490	COG0823	Involved in the tonB-independent uptake of proteins
FOC14_RS16490	COG1506	peptidase
FOC14_RS16490	COG4946	Tricorn protease homolog
FOC14_RS16525	COG2011	ABC-type metal ion transport system permease component
FOC14_RS16530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC14_RS16535	COG1464	Belongs to the NlpA lipoprotein family
FOC14_RS16550	COG0277	FAD linked oxidase domain protein
FOC14_RS16555	COG2271	Major facilitator Superfamily
FOC14_RS16565	COG2814	Major facilitator Superfamily
FOC14_RS16580	COG0601	transmembrane transport
FOC14_RS16585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC14_RS16590	COG0444	Belongs to the ABC transporter superfamily
FOC14_RS16595	COG4608	Belongs to the ABC transporter superfamily
FOC14_RS16600	COG4166	transmembrane transport
FOC14_RS16610	COG2207	Transcriptional regulator
FOC14_RS16625	COG4166	transmembrane transport
FOC14_RS16630	COG4166	transmembrane transport
FOC14_RS16635	COG0656	L-ascorbic acid biosynthetic process
FOC14_RS16640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC14_RS16650	COG4975	Glucose uptake
FOC14_RS16655	COG4149	molybdate abc transporter
FOC14_RS16665	COG1910	domain protein
FOC14_RS16675	COG0583	DNA-binding transcription factor activity
FOC14_RS16680	COG0697	spore germination
FOC14_RS16695	COG0204	Acyl-transferase
FOC14_RS16705	COG1609	Transcriptional regulator
FOC14_RS16715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS16725	COG0084	hydrolase, TatD family'
FOC14_RS16730	COG5298	Protein conserved in bacteria
FOC14_RS16750	COG0488	(ABC) transporter
FOC14_RS16765	COG0747	negative chemotaxis
FOC14_RS16770	COG0601	transmembrane transport
FOC14_RS16780	COG0444	Belongs to the ABC transporter superfamily
FOC14_RS16785	COG4608	Belongs to the ABC transporter superfamily
FOC14_RS16805	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC14_RS16810	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC14_RS16820	COG2814	Major facilitator Superfamily
FOC14_RS16830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC14_RS16840	COG4294	response to UV
FOC14_RS16845	COG0457	Tetratricopeptide repeat
FOC14_RS16845	COG0705	Rhomboid family
FOC14_RS16855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC14_RS16860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC14_RS16865	COG0864	Transcriptional regulator
FOC14_RS16870	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC14_RS16875	COG2183	response to ionizing radiation
FOC14_RS16970	COG0802	atpase or kinase
FOC14_RS16975	COG1214	PFAM Peptidase M22, glycoprotease
FOC14_RS16980	COG0456	acetyltransferase
FOC14_RS16985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC14_RS16990	COG0488	(ABC) transporter
FOC14_RS17005	COG1266	CAAX protease self-immunity
FOC14_RS17025	COG2252	PERMEase
FOC14_RS17035	COG5002	protein histidine kinase activity
FOC14_RS17065	COG2226	methyltransferase
FOC14_RS17105	COG1968	undecaprenyl-diphosphatase activity
FOC14_RS17120	COG2205	protein histidine kinase activity
FOC14_RS17125	COG0745	RESPONSE REGULATOR receiver
FOC14_RS17145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC14_RS17150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC14_RS17155	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC14_RS17165	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC14_RS17180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC14_RS17190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC14_RS17200	COG0151	Belongs to the GarS family
FOC14_RS17225	COG0210	DNA helicase
FOC14_RS17235	COG4851	CamS sex pheromone cAM373 precursor
FOC14_RS17250	COG1335	isochorismatase
FOC14_RS17255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC14_RS17260	COG2011	ABC-type metal ion transport system permease component
FOC14_RS17265	COG1464	Belongs to the NlpA lipoprotein family
FOC14_RS17285	COG1846	Transcriptional regulator
FOC14_RS17310	COG1597	lipid kinase activity
FOC14_RS17315	COG0546	phosphoglycolate phosphatase activity
FOC14_RS17320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC14_RS17330	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS17335	COG2076	Multidrug Resistance protein
FOC14_RS17340	COG2309	aminopeptidase activity
FOC14_RS17355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS17360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC14_RS17365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC14_RS17375	COG4807	Protein conserved in bacteria
FOC14_RS17405	COG1473	amidohydrolase
FOC14_RS17420	COG0450	alkyl hydroperoxide reductase
FOC14_RS17425	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FOC14_RS17435	COG0235	Class ii aldolase
FOC14_RS17440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS17445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS17450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS17465	COG0166	Belongs to the GPI family
FOC14_RS17500	COG5002	protein histidine kinase activity
FOC14_RS17520	COG3541	Predicted nucleotidyltransferase
FOC14_RS17525	COG2814	Major facilitator Superfamily
FOC14_RS17530	COG0723	plastoquinol--plastocyanin reductase activity
FOC14_RS17530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC14_RS17540	COG0765	amino acid transport
FOC14_RS17545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC14_RS17555	COG0840	transmembrane signaling receptor activity
FOC14_RS17560	COG0840	transmembrane signaling receptor activity
FOC14_RS17565	COG0366	Alpha amylase catalytic
FOC14_RS17570	COG2190	(PTS) system
FOC14_RS17570	COG1263	PTS System
FOC14_RS17570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC14_RS17600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC14_RS17615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC14_RS17625	COG1116	anion transmembrane transporter activity
FOC14_RS17630	COG0488	(ABC) transporter
FOC14_RS17675	COG2270	Major facilitator Superfamily
FOC14_RS17690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC14_RS17705	COG2310	stress, protein
FOC14_RS17710	COG2310	stress, protein
FOC14_RS17715	COG2310	stress, protein
FOC14_RS17720	COG0861	Integral membrane protein TerC family
FOC14_RS17730	COG3853	Toxic anion resistance protein (TelA)
FOC14_RS17745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC14_RS17755	COG1295	ribonuclease BN
FOC14_RS17760	COG2217	Heavy metal translocating P-type atpase
FOC14_RS17765	COG0697	spore germination
FOC14_RS17785	COG0586	Pfam SNARE associated Golgi protein
FOC14_RS17800	COG3871	stress protein (general stress protein 26)
FOC14_RS17805	COG0387	Pfam Sodium calcium exchanger
FOC14_RS17815	COG0535	radical SAM domain protein
FOC14_RS17840	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC14_RS17845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC14_RS17850	COG0582	viral genome integration into host DNA
FOC14_RS17855	COG1396	sequence-specific DNA binding
FOC14_RS17870	COG1396	sequence-specific DNA binding
FOC14_RS17905	COG1484	DNA-dependent DNA replication
FOC14_RS17990	COG0582	viral genome integration into host DNA
FOC14_RS17995	COG0582	viral genome integration into host DNA
FOC14_RS18115	COG0101	tRNA pseudouridine synthase activity
FOC14_RS18125	COG3829	transcription factor binding
FOC14_RS18135	COG0833	amino acid
FOC14_RS18140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC14_RS18160	COG2066	Belongs to the glutaminase family
FOC14_RS18165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC14_RS18165	COG1263	PTS System
FOC14_RS18170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC14_RS18185	COG0463	Glycosyl transferase, family 2
FOC14_RS18200	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC14_RS18200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC14_RS18220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC14_RS18240	COG1228	amidohydrolase
FOC14_RS18245	COG1090	epimerase
FOC14_RS18275	COG1988	membrane-bound metal-dependent
FOC14_RS18280	COG1194	a g-specific adenine glycosylase
FOC14_RS18305	COG1132	(ABC) transporter
FOC14_RS18310	COG4129	membrane
FOC14_RS18315	COG0070	glutamate synthase
FOC14_RS18315	COG0069	glutamate synthase activity
FOC14_RS18315	COG0067	glutamate synthase
FOC14_RS18325	COG4555	ABC transporter
FOC14_RS18345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC14_RS18350	COG0735	belongs to the Fur family
FOC14_RS18465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC14_RS18470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC14_RS18480	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC14_RS18490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC14_RS18500	COG2766	serine protein kinase
FOC14_RS18520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC14_RS18530	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC14_RS18535	COG2268	Band 7 protein
FOC14_RS18545	COG3290	protein histidine kinase activity
FOC14_RS18555	COG2851	Citrate transporter
FOC14_RS18575	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC14_RS18580	COG3842	ATPase activity
FOC14_RS18585	COG1175	transmembrane transport
FOC14_RS18590	COG0395	ABC-type sugar transport system, permease component
FOC14_RS18600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC14_RS18605	COG0745	RESPONSE REGULATOR receiver
FOC14_RS18610	COG5002	protein histidine kinase activity
FOC14_RS18620	COG4990	cell redox homeostasis
FOC14_RS18630	COG3290	protein histidine kinase activity
FOC14_RS18635	COG4565	transcriptional regulatory protein
FOC14_RS18640	COG3493	citrate carrier protein
FOC14_RS18645	COG0281	malic enzyme
FOC14_RS18660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS18670	COG5002	protein histidine kinase activity
FOC14_RS18675	COG0745	RESPONSE REGULATOR receiver
FOC14_RS18680	COG0456	acetyltransferase
FOC14_RS18680	COG0454	-acetyltransferase
FOC14_RS18685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC14_RS18690	COG3383	formate dehydrogenase (NAD+) activity
FOC14_RS18695	COG2427	Protein of unknown function (DUF1641)
FOC14_RS18710	COG0531	amino acid
FOC14_RS18715	COG0640	Transcriptional regulator
FOC14_RS18720	COG2217	Heavy metal translocating P-type atpase
FOC14_RS18725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC14_RS18740	COG3227	Zinc metalloprotease (Elastase)
FOC14_RS18760	COG2720	vancomycin resistance protein
FOC14_RS18765	COG1316	TRANSCRIPTIONal
FOC14_RS18770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS18775	COG0346	lactoylglutathione lyase activity
FOC14_RS18780	COG1253	flavin adenine dinucleotide binding
FOC14_RS18785	COG1027	Aspartate ammonia-lyase
FOC14_RS18790	COG1620	l-lactate permease
FOC14_RS18805	COG3104	oligopeptide transport
FOC14_RS18810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS18815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS18820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC14_RS18830	COG2226	methyltransferase
FOC14_RS18835	COG0156	8-amino-7-oxononanoate synthase activity
FOC14_RS18840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC14_RS18850	COG4548	von Willebrand factor, type A
FOC14_RS18855	COG0714	Associated with various cellular activities
FOC14_RS18860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC14_RS18880	COG0531	amino acid
FOC14_RS18885	COG2188	Transcriptional regulator
FOC14_RS18890	COG1263	PTS System
FOC14_RS18890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC14_RS18895	COG0366	Alpha amylase catalytic
FOC14_RS18910	COG0697	spore germination
FOC14_RS18920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC14_RS18925	COG1115	amino acid carrier protein
FOC14_RS18930	COG1126	abc transporter atp-binding protein
FOC14_RS18935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC14_RS18940	COG0765	amino acid transport
FOC14_RS18945	COG0765	amino acid transport
FOC14_RS18950	COG0833	amino acid
FOC14_RS18975	COG2378	regulation of single-species biofilm formation
FOC14_RS18980	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC14_RS18985	COG5002	protein histidine kinase activity
FOC14_RS19000	COG0659	secondary active sulfate transmembrane transporter activity
FOC14_RS19015	COG0747	negative chemotaxis
FOC14_RS19025	COG0601	transmembrane transport
FOC14_RS19030	COG4608	Belongs to the ABC transporter superfamily
FOC14_RS19040	COG2271	Major facilitator Superfamily
FOC14_RS19045	COG1846	Transcriptional regulator
FOC14_RS19055	COG1609	Transcriptional regulator
FOC14_RS19060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC14_RS19075	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC14_RS19080	COG1879	ABC-type sugar transport system periplasmic component
FOC14_RS19085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC14_RS19105	COG1063	alcohol dehydrogenase
FOC14_RS19120	COG3568	Endonuclease Exonuclease Phosphatase
FOC14_RS19145	COG1968	undecaprenyl-diphosphatase activity
FOC14_RS19150	COG0840	transmembrane signaling receptor activity
FOC14_RS19155	COG3584	3D domain protein
FOC14_RS19155	COG1388	LysM domain
FOC14_RS19160	COG1476	TRANSCRIPTIONal
FOC14_RS19175	COG3104	oligopeptide transport
FOC14_RS19180	COG1114	Component of the transport system for branched-chain amino acids
FOC14_RS19195	COG1113	amino acid transport
FOC14_RS19200	COG2252	PERMEase
FOC14_RS19225	COG0475	glutathione-regulated potassium exporter activity
FOC14_RS19225	COG0569	domain protein
FOC14_RS19240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC14_RS19245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC14_RS19250	COG0833	amino acid
FOC14_RS19255	COG4990	cell redox homeostasis
FOC14_RS19270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC14_RS19275	COG0697	spore germination
FOC14_RS19280	COG0531	amino acid
FOC14_RS19290	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC14_RS19295	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC14_RS19300	COG1918	ferrous iron import across plasma membrane
FOC14_RS19300	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC14_RS19305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC14_RS19310	COG0573	inorganic phosphate transmembrane transporter activity
FOC14_RS19315	COG0581	inorganic phosphate transmembrane transporter activity
FOC14_RS19325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC14_RS19440	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC14_RS19460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC14_RS19465	COG1116	anion transmembrane transporter activity
FOC14_RS19470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC14_RS19475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC14_RS19480	COG0352	thiamine-phosphate diphosphorylase activity
FOC14_RS19485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC14_RS19490	COG2104	thiamine diphosphate biosynthetic process
FOC14_RS19500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC14_RS19505	COG0351	phosphomethylpyrimidine kinase
FOC14_RS19545	COG2205	protein histidine kinase activity
FOC14_RS19550	COG2814	Major facilitator Superfamily
FOC14_RS19555	COG1846	Transcriptional regulator
FOC14_RS19570	COG2252	PERMEase
FOC14_RS19575	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS19590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC14_RS19595	COG1621	beta-fructofuranosidase activity
FOC14_RS19600	COG1263	PTS System
FOC14_RS19600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC14_RS19605	COG1609	Transcriptional regulator
FOC14_RS19615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC14_RS19620	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOC14_RS19655	COG0778	Nitroreductase
FOC14_RS19660	COG2719	SpoVR family
FOC14_RS19685	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC14_RS19690	COG1937	Protein conserved in bacteria
FOC14_RS19695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC14_RS19695	COG0425	Belongs to the sulfur carrier protein TusA family
FOC14_RS19700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC14_RS19700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC14_RS19705	COG0425	Belongs to the sulfur carrier protein TusA family
FOC14_RS19710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC14_RS19720	COG2210	Belongs to the sulfur carrier protein TusA family
FOC14_RS19725	COG0730	response to heat
FOC14_RS19735	COG1316	TRANSCRIPTIONal
FOC14_RS19740	COG0604	alcohol dehydrogenase
FOC14_RS19745	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC14_RS19760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC14_RS19760	COG3711	transcriptional antiterminator
FOC14_RS19765	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC14_RS19770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC14_RS19790	COG1388	LysM domain
FOC14_RS19790	COG3584	3D domain protein
FOC14_RS19795	COG0577	efflux transmembrane transporter activity
FOC14_RS19800	COG1136	(ABC) transporter
FOC14_RS19810	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC14_RS19825	COG1114	Component of the transport system for branched-chain amino acids
FOC14_RS19830	COG3546	catalase activity
FOC14_RS19865	COG0586	Pfam SNARE associated Golgi protein
FOC14_RS19895	COG0531	amino acid
FOC14_RS19900	COG0475	glutathione-regulated potassium exporter activity
FOC14_RS19910	COG1737	Transcriptional regulator
FOC14_RS19920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC14_RS19920	COG1263	PTS System
FOC14_RS19930	COG2259	Doxx family
FOC14_RS19945	COG0697	spore germination
FOC14_RS19950	COG1522	sequence-specific DNA binding
FOC14_RS19960	COG2076	Multidrug Resistance protein
FOC14_RS19965	COG2076	Multidrug Resistance protein
FOC14_RS19970	COG1309	transcriptional regulator
FOC14_RS19975	COG2814	Major facilitator Superfamily
FOC14_RS19980	COG1733	regulation of RNA biosynthetic process
FOC14_RS19990	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC14_RS19995	COG4533	DNA binding
FOC14_RS20000	COG2211	Major facilitator Superfamily
FOC14_RS20010	COG0693	protein deglycase activity
FOC14_RS20015	COG0693	protein deglycase activity
FOC14_RS20015	COG0753	catalase activity
FOC14_RS20025	COG0531	amino acid
FOC14_RS20030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC14_RS20040	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS20045	COG1132	(ABC) transporter
FOC14_RS20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC14_RS20060	COG0765	amino acid transport
FOC14_RS20065	COG1126	abc transporter atp-binding protein
FOC14_RS20080	COG0189	ligase activity
FOC14_RS20110	COG0028	Belongs to the TPP enzyme family
FOC14_RS20115	COG3527	Alpha-acetolactate decarboxylase
FOC14_RS20130	COG0561	phosphatase activity
FOC14_RS20145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC14_RS20160	COG0659	secondary active sulfate transmembrane transporter activity
FOC14_RS20180	COG0653	protein targeting
FOC14_RS20185	COG2244	polysaccharide biosynthetic process
FOC14_RS20195	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS20200	COG4196	transglutaminase domain protein
FOC14_RS20215	COG1696	Membrane protein involved in D-alanine export
FOC14_RS20230	COG1024	Enoyl-CoA hydratase
FOC14_RS20250	COG1363	Peptidase, m42
FOC14_RS20270	COG3938	Belongs to the proline racemase family
FOC14_RS20305	COG0601	transmembrane transport
FOC14_RS20310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC14_RS20320	COG4608	Belongs to the ABC transporter superfamily
FOC14_RS20325	COG0322	excinuclease ABC activity
FOC14_RS20355	COG0477	Major facilitator Superfamily
FOC14_RS20360	COG3290	protein histidine kinase activity
FOC14_RS20365	COG4565	transcriptional regulatory protein
FOC14_RS20370	COG3181	Tripartite tricarboxylate transporter family receptor
FOC14_RS20400	COG4978	Transcriptional regulator
FOC14_RS20400	COG0789	Transcriptional regulator
FOC14_RS20415	COG0305	Participates in initiation and elongation during chromosome replication
FOC14_RS20445	COG0477	Major facilitator Superfamily
FOC14_RS20490	COG3320	Male sterility
FOC14_RS20490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC14_RS20515	COG1183	phosphatidylcholine synthase activity
FOC14_RS20535	COG2376	Dihydroxyacetone kinase
FOC14_RS20545	COG2376	Dihydroxyacetone kinase
FOC14_RS20550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC14_RS20555	COG1959	2 iron, 2 sulfur cluster binding
FOC14_RS20585	COG3437	response regulator, receiver
FOC14_RS20585	COG2770	Histidine kinase
FOC14_RS20635	COG3237	CsbD-like
FOC14_RS20660	COG1191	sigma factor activity
FOC14_RS20670	COG2208	phosphoserine phosphatase activity
FOC14_RS20675	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC14_RS20680	COG2205	protein histidine kinase activity
FOC14_RS20680	COG0784	Response regulator, receiver
FOC14_RS20680	COG2198	Histidine kinase
FOC14_RS20680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC14_RS20700	COG0393	Putative heavy-metal-binding
FOC14_RS20730	COG0420	3'-5' exonuclease activity
FOC14_RS20755	COG1309	transcriptional regulator
FOC14_RS20760	COG2814	Major facilitator Superfamily
FOC14_RS20765	COG0346	lactoylglutathione lyase activity
FOC14_RS20770	COG0346	lactoylglutathione lyase activity
FOC14_RS20775	COG0457	Tetratricopeptide repeat
FOC14_RS20780	COG2267	carboxylic ester hydrolase activity
FOC14_RS20800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC14_RS20805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC14_RS20815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC14_RS20850	COG0477	Major facilitator Superfamily
FOC14_RS20855	COG0477	Major facilitator Superfamily
FOC14_RS20865	COG3973	AAA domain
FOC14_RS20870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC14_RS20890	COG4980	gas vesicle protein
FOC14_RS20895	COG0537	adenosine 5'-monophosphoramidase activity
FOC14_RS20900	COG1131	(ABC) transporter
FOC14_RS20905	COG4473	ABC transporter
FOC14_RS20920	COG1309	transcriptional regulator
FOC14_RS20925	COG3402	PFAM membrane-flanked domain
FOC14_RS20970	COG3402	PFAM membrane-flanked domain
FOC14_RS20975	COG3428	Bacterial PH domain
FOC14_RS20980	COG2329	Antibiotic biosynthesis monooxygenase
FOC14_RS20985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC14_RS20990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC14_RS21035	COG1309	transcriptional regulator
FOC14_RS21040	COG1511	domain protein
FOC14_RS21065	COG1609	Transcriptional regulator
FOC14_RS21075	COG1234	tRNA 3'-trailer cleavage
FOC14_RS21080	COG0095	Lipoate-protein ligase
FOC14_RS21090	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS21120	COG3209	COG3209 Rhs family protein
FOC14_RS21155	COG1078	dGTPase activity
FOC14_RS21165	COG1595	DNA-templated transcription, initiation
FOC14_RS21170	COG3708	Transcriptional regulator
FOC14_RS21170	COG2207	Transcriptional regulator
FOC14_RS21180	COG2205	protein histidine kinase activity
FOC14_RS21185	COG0745	RESPONSE REGULATOR receiver
FOC14_RS21210	COG0501	Belongs to the peptidase M48B family
FOC14_RS21215	COG0840	transmembrane signaling receptor activity
FOC14_RS21220	COG0697	spore germination
FOC14_RS21235	COG0497	DNA recombination
FOC14_RS21240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC14_RS21245	COG2224	Isocitrate lyase
FOC14_RS21255	COG1278	Cold shock
FOC14_RS21270	COG4903	ComK protein
FOC14_RS21275	COG0398	Pfam SNARE associated Golgi protein
FOC14_RS21285	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FOC14_RS21290	COG1074	ATP-dependent DNA helicase activity
FOC14_RS21335	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC14_RS21360	COG0367	asparagine synthase
FOC14_RS21370	COG0753	catalase activity
FOC14_RS21395	COG2996	Protein conserved in bacteria
FOC14_RS21405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC14_RS21415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS21430	COG0561	phosphatase activity
FOC14_RS21440	COG0542	response to heat
FOC14_RS21450	COG2267	carboxylic ester hydrolase activity
FOC14_RS21465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC14_RS21470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC14_RS21475	COG5504	Zn-dependent protease
FOC14_RS21485	COG0180	Tryptophanyl-tRNA synthetase
FOC14_RS21495	COG4166	transmembrane transport
FOC14_RS21500	COG0601	transmembrane transport
FOC14_RS21505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC14_RS21510	COG0444	Belongs to the ABC transporter superfamily
FOC14_RS21515	COG4608	Belongs to the ABC transporter superfamily
FOC14_RS21520	COG0534	Mate efflux family protein
FOC14_RS21525	COG4166	transmembrane transport
FOC14_RS21535	COG1393	Belongs to the ArsC family
FOC14_RS21540	COG0861	Integral membrane protein TerC family
FOC14_RS21545	COG4862	establishment of competence for transformation
FOC14_RS21550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC14_RS21560	COG1164	Oligoendopeptidase f
FOC14_RS21570	COG2346	COG2346, Truncated hemoglobins
FOC14_RS21575	COG4116	CYTH
FOC14_RS21585	COG2357	RelA SpoT domain protein
FOC14_RS21590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC14_RS21595	COG0564	pseudouridine synthase activity
FOC14_RS21615	COG1216	Glycosyl transferase, family 2
FOC14_RS21635	COG0463	Glycosyl transferase, family 2
FOC14_RS21635	COG0457	Tetratricopeptide repeat
FOC14_RS21655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC14_RS21670	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC14_RS21715	COG2153	protein acetylation
FOC14_RS21720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC14_RS21725	COG2382	esterase
FOC14_RS21740	COG5492	domain, Protein
FOC14_RS21745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC14_RS21755	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC14_RS21755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC14_RS21790	COG1620	l-lactate permease
FOC14_RS21795	COG5634	Uncharacterized conserved protein (DUF2278)
FOC14_RS21850	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC14_RS21860	COG1476	TRANSCRIPTIONal
FOC14_RS21920	COG2226	methyltransferase
FOC14_RS21930	COG1686	Belongs to the peptidase S11 family
FOC14_RS21935	COG0681	Belongs to the peptidase S26 family
FOC14_RS21970	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS21975	COG3842	ATPase activity
FOC14_RS21980	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC14_RS21985	COG1177	transmembrane transport
FOC14_RS21990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC14_RS22000	COG2409	Drug exporters of the RND superfamily
FOC14_RS22010	COG0564	pseudouridine synthase activity
FOC14_RS22020	COG2340	Cysteine-rich secretory protein family
FOC14_RS22025	COG0247	lactate metabolic process
FOC14_RS22030	COG0277	FAD linked oxidase domain protein
FOC14_RS22035	COG3835	regulator
FOC14_RS22045	COG0745	RESPONSE REGULATOR receiver
FOC14_RS22050	COG5002	protein histidine kinase activity
FOC14_RS22055	COG2186	Transcriptional regulator
FOC14_RS22075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC14_RS22085	COG2116	formate transmembrane transporter activity
FOC14_RS22090	COG0861	Integral membrane protein TerC family
FOC14_RS22095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC14_RS22105	COG2030	dehydratase
FOC14_RS22125	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS22130	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC14_RS22140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC14_RS22150	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC14_RS22165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC14_RS22180	COG1349	DNA-binding transcription factor activity
FOC14_RS22200	COG2861	carbohydrate metabolic process
FOC14_RS22210	COG3852	Histidine kinase
FOC14_RS22215	COG1846	Transcriptional regulator
FOC14_RS22225	COG2318	DinB family
FOC14_RS22230	COG5002	protein histidine kinase activity
FOC14_RS22240	COG0720	synthase
FOC14_RS22255	COG4873	Protein conserved in bacteria
FOC14_RS22280	COG1780	Probably involved in ribonucleotide reductase function
FOC14_RS22300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC14_RS22305	COG1725	Transcriptional regulator
FOC14_RS22310	COG1131	(ABC) transporter
FOC14_RS22320	COG1131	(ABC) transporter
FOC14_RS22325	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC14_RS22340	COG1522	sequence-specific DNA binding
FOC14_RS22350	COG1335	isochorismatase
FOC14_RS22360	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC14_RS22365	COG2070	2-Nitropropane dioxygenase
FOC14_RS22370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC14_RS22380	COG1696	Membrane protein involved in D-alanine export
FOC14_RS22400	COG0716	FMN binding
FOC14_RS22410	COG3173	Aminoglycoside phosphotransferase
FOC14_RS22425	COG0534	Mate efflux family protein
FOC14_RS22430	COG1968	undecaprenyl-diphosphatase activity
FOC14_RS22445	COG1846	Transcriptional regulator
FOC14_RS22455	COG1301	dicarboxylic acid transport
FOC14_RS22460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC14_RS22465	COG4709	membrane
FOC14_RS22470	COG3874	Sporulation protein YtfJ
FOC14_RS22495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC14_RS22500	COG0028	Belongs to the TPP enzyme family
FOC14_RS22505	COG0440	acetolactate synthase activity
FOC14_RS22510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC14_RS22520	COG0473	3-isopropylmalate dehydrogenase activity
FOC14_RS22545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC14_RS22580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC14_RS22595	COG1183	phosphatidylcholine synthase activity
FOC14_RS22600	COG1368	sulfuric ester hydrolase activity
FOC14_RS22610	COG0019	diaminopimelate decarboxylase activity
FOC14_RS22630	COG0529	Catalyzes the synthesis of activated sulfate
FOC14_RS22635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC14_RS22655	COG1648	precorrin-2 dehydrogenase activity
FOC14_RS22660	COG0733	neurotransmitter:sodium symporter activity
FOC14_RS22680	COG1757	Na H antiporter
FOC14_RS22695	COG4758	membrane
FOC14_RS22700	COG4585	Histidine kinase
FOC14_RS22705	COG2197	response regulator
FOC14_RS22715	COG1114	Component of the transport system for branched-chain amino acids
FOC14_RS22725	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC14_RS22750	COG1017	nitric oxide dioxygenase activity
FOC14_RS22750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOC14_RS22765	COG0730	response to heat
FOC14_RS22770	COG0306	phosphate transporter
FOC14_RS22775	COG1392	Phosphate transport regulator
FOC14_RS22780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC14_RS22800	COG1801	Protein of unknown function DUF72
FOC14_RS22810	COG0582	viral genome integration into host DNA
FOC14_RS22815	COG5002	protein histidine kinase activity
FOC14_RS22835	COG0392	lysyltransferase activity
FOC14_RS22835	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC14_RS22850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC14_RS22855	COG1686	Belongs to the peptidase S11 family
FOC14_RS22860	COG2715	membrane protein required for spore maturation
FOC14_RS22865	COG0700	Nucleoside recognition
FOC14_RS22870	COG1187	pseudouridine synthase activity
FOC14_RS22880	COG1333	cytochrome c biogenesis protein
FOC14_RS22885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC14_RS22890	COG0745	RESPONSE REGULATOR receiver
FOC14_RS22895	COG5002	protein histidine kinase activity
FOC14_RS22900	COG2096	Adenosyltransferase
FOC14_RS22915	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC14_RS22920	COG1141	Ferredoxin
FOC14_RS22925	COG4955	Helix-turn-helix domain
FOC14_RS22930	COG0514	ATP-dependent DNA helicase (RecQ)
FOC14_RS22935	COG1266	CAAX protease self-immunity
FOC14_RS22955	COG4862	establishment of competence for transformation
FOC14_RS22960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC14_RS22980	COG0492	ferredoxin-NADP+ reductase activity
FOC14_RS23055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC14_RS23070	COG0142	geranyltranstransferase activity
FOC14_RS23080	COG0142	geranyltranstransferase activity
FOC14_RS23085	COG0105	UTP biosynthetic process
FOC14_RS23100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC14_RS23105	COG0457	Tetratricopeptide repeat
FOC14_RS23125	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC14_RS23135	COG4347	Protein of unknown function (DUF1405)
FOC14_RS23150	COG2738	Putative neutral zinc metallopeptidase
FOC14_RS23160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS23165	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC14_RS23180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC14_RS23185	COG0438	transferase activity, transferring glycosyl groups
FOC14_RS23220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC14_RS23220	COG1199	ATP-dependent helicase activity
FOC14_RS23240	COG3935	DnaD domain protein
FOC14_RS23245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC14_RS23255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC14_RS23255	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC14_RS23295	COG4474	Belongs to the UPF0398 family
FOC14_RS23310	COG0116	Belongs to the methyltransferase superfamily
FOC14_RS23320	COG1199	ATP-dependent helicase activity
FOC14_RS23325	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC14_RS23335	COG3173	Aminoglycoside phosphotransferase
FOC14_RS23340	COG0024	Methionine aminopeptidase
FOC14_RS23355	COG2233	PERMEase
FOC14_RS23360	COG2311	Membrane
FOC14_RS23365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC14_RS23375	COG0456	acetyltransferase
FOC14_RS23425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC14_RS23450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC14_RS23465	COG1215	transferase activity, transferring glycosyl groups
FOC14_RS23485	COG0454	-acetyltransferase
FOC14_RS23505	COG0328	RNA-DNA hybrid ribonuclease activity
FOC14_RS23545	COG1280	lysine exporter protein (LysE YggA)
FOC14_RS23560	COG3162	membrane
FOC14_RS23565	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC14_RS23570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC14_RS23580	COG0475	glutathione-regulated potassium exporter activity
FOC14_RS23590	COG0789	Transcriptional regulator
FOC14_RS23590	COG4978	Transcriptional regulator
FOC14_RS23600	COG2323	membrane
FOC14_RS23605	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC14_RS23660	COG1923	regulation of RNA biosynthetic process
FOC14_RS23670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC14_RS23675	COG1360	Flagellar Motor Protein
FOC14_RS23680	COG2201	protein-glutamate methylesterase activity
FOC14_RS23690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC14_RS23690	COG1776	CheC inhibitor of MCP methylation
FOC14_RS23705	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC14_RS23725	COG1256	bacterial-type flagellum assembly
FOC14_RS23750	COG1815	bacterial-type flagellum-dependent cell motility
FOC14_RS23755	COG1558	bacterial-type flagellum-dependent cell motility
FOC14_RS23760	COG1677	Flagellar hook-basal body complex protein FliE
FOC14_RS23770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC14_RS23780	COG1157	protein secretion by the type III secretion system
FOC14_RS23830	COG0463	Glycosyl transferase, family 2
FOC14_RS23865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC14_RS23870	COG0741	lytic transglycosylase activity
FOC14_RS23885	COG1776	CheC inhibitor of MCP methylation
FOC14_RS23885	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC14_RS23895	COG1338	Plays a role in the flagellum-specific transport system
FOC14_RS23900	COG1987	bacterial-type flagellum assembly
FOC14_RS23910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC14_RS23915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC14_RS23925	COG4786	Flagellar basal body rod
FOC14_RS23930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC14_RS23955	COG1309	transcriptional regulator
FOC14_RS23975	COG2329	Antibiotic biosynthesis monooxygenase
FOC14_RS24005	COG3842	ATPase activity
FOC14_RS24010	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC14_RS24015	COG1177	transmembrane transport
FOC14_RS24020	COG1234	tRNA 3'-trailer cleavage
FOC14_RS24050	COG1686	Belongs to the peptidase S11 family
FOC14_RS24060	COG0406	alpha-ribazole phosphatase activity
FOC14_RS24090	COG0367	asparagine synthase
FOC14_RS24120	COG1802	Transcriptional regulator
FOC14_RS24125	COG0697	spore germination
FOC14_RS24130	COG0523	cobalamin synthesis protein
FOC14_RS24135	COG0701	Predicted permease
FOC14_RS24145	COG0438	transferase activity, transferring glycosyl groups
FOC14_RS24145	COG1216	Glycosyl transferase, family 2
FOC14_RS24150	COG1757	Na H antiporter
FOC14_RS24155	COG0114	fumarate hydratase activity
FOC14_RS24180	COG3340	Belongs to the peptidase S51 family
FOC14_RS24200	COG0785	Cytochrome C biogenesis protein
FOC14_RS24230	COG2733	membrane
FOC14_RS24265	COG1131	(ABC) transporter
FOC14_RS24280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC14_RS24285	COG0528	UMP kinase activity
FOC14_RS24295	COG1027	Aspartate ammonia-lyase
FOC14_RS24300	COG0281	malic enzyme
FOC14_RS24305	COG4191	Histidine kinase
FOC14_RS24310	COG0784	Response regulator, receiver
FOC14_RS24315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC14_RS24365	COG1051	belongs to the nudix hydrolase family
FOC14_RS24370	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS24395	COG1966	Carbon starvation protein
FOC14_RS24410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC14_RS24430	COG2223	nitrite transmembrane transporter activity
FOC14_RS24435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC14_RS24450	COG2244	polysaccharide biosynthetic process
FOC14_RS24455	COG0733	neurotransmitter:sodium symporter activity
FOC14_RS24465	COG5566	PFAM Mor transcription activator
FOC14_RS24470	COG2323	membrane
FOC14_RS24485	COG2084	Dehydrogenase
FOC14_RS24500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC14_RS24510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC14_RS24515	COG0028	Belongs to the TPP enzyme family
FOC14_RS24520	COG0440	acetolactate synthase activity
FOC14_RS24525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC14_RS24535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC14_RS24560	COG2814	Major facilitator Superfamily
FOC14_RS24565	COG3384	dioxygenase
FOC14_RS24575	COG3279	Response regulator of the LytR AlgR family
FOC14_RS24580	COG0427	acetyl-CoA hydrolase
FOC14_RS24600	COG1073	alpha beta
FOC14_RS24635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC14_RS24655	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC14_RS24670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC14_RS24700	COG2390	Transcriptional regulator
FOC14_RS24710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC14_RS24715	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC14_RS24730	COG4224	UPF0291 protein
FOC14_RS24750	COG0006	proline dipeptidase activity
FOC14_RS24755	COG2132	Multicopper oxidase
FOC14_RS24785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC14_RS24800	COG2372	response to copper ion
FOC14_RS24800	COG1276	copper resistance
FOC14_RS24805	COG4549	nuclear export factor GLE1
FOC14_RS24815	COG0697	spore germination
FOC14_RS24820	COG0583	DNA-binding transcription factor activity
FOC14_RS24825	COG1959	2 iron, 2 sulfur cluster binding
FOC14_RS24830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC14_RS24835	COG0778	Nitroreductase
FOC14_RS24845	COG0628	permease
FOC14_RS24850	COG0039	L-malate dehydrogenase activity
FOC14_RS24855	COG1231	oxidoreductase activity
FOC14_RS24860	COG0523	cobalamin synthesis protein
FOC14_RS24875	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS24880	COG2030	dehydratase
FOC14_RS24885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC14_RS24895	COG0411	ABC transporter
FOC14_RS24915	COG0583	DNA-binding transcription factor activity
FOC14_RS24935	COG1846	Transcriptional regulator
FOC14_RS24945	COG1271	oxidase subunit
FOC14_RS24950	COG1294	oxidase, subunit
FOC14_RS24955	COG4988	ABC transporter
FOC14_RS24960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC14_RS24980	COG1686	Belongs to the peptidase S11 family
FOC14_RS24995	COG0791	NLP P60 protein
FOC14_RS24995	COG1388	LysM domain
FOC14_RS25010	COG0745	RESPONSE REGULATOR receiver
FOC14_RS25015	COG5002	protein histidine kinase activity
FOC14_RS25025	COG0300	oxidoreductase activity
FOC14_RS25040	COG0726	polysaccharide deacetylase
FOC14_RS25060	COG0460	homoserine dehydrogenase
FOC14_RS25085	COG1316	TRANSCRIPTIONal
FOC14_RS25095	COG0745	RESPONSE REGULATOR receiver
FOC14_RS25100	COG5002	protein histidine kinase activity
FOC14_RS25105	COG0726	polysaccharide deacetylase
FOC14_RS25115	COG1285	pathogenesis
FOC14_RS25120	COG1247	-acetyltransferase
FOC14_RS25130	COG4264	IucA IucC family
FOC14_RS25135	COG0318	PFAM AMP-dependent synthetase and ligase
FOC14_RS25150	COG1082	Xylose isomerase domain protein TIM barrel
FOC14_RS25165	COG1279	arginine transmembrane transporter activity
FOC14_RS25175	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC14_RS25215	COG2002	toxin-antitoxin pair type II binding
FOC14_RS25220	COG1404	Belongs to the peptidase S8 family
FOC14_RS25225	COG0640	Transcriptional regulator
FOC14_RS25230	COG0667	Aldo Keto reductase
FOC14_RS25235	COG2814	Major facilitator Superfamily
FOC14_RS25260	COG0840	transmembrane signaling receptor activity
FOC14_RS25275	COG3949	Membrane
FOC14_RS25280	COG0783	Belongs to the Dps family
FOC14_RS25295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC14_RS25305	COG1231	oxidoreductase activity
FOC14_RS25315	COG4989	oxidoreductase activity
FOC14_RS25320	COG0523	cobalamin synthesis protein
FOC14_RS25325	COG0456	acetyltransferase
FOC14_RS25375	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC14_RS25375	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC14_RS25380	COG0702	epimerase
FOC14_RS25390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC14_RS25400	COG4166	transmembrane transport
FOC14_RS25415	COG0406	alpha-ribazole phosphatase activity
FOC14_RS25425	COG5337	Spore coat protein CotH
FOC14_RS25430	COG1051	belongs to the nudix hydrolase family
FOC14_RS25435	COG0586	Pfam SNARE associated Golgi protein
FOC14_RS25440	COG2244	polysaccharide biosynthetic process
FOC14_RS25450	COG0701	Predicted permease
FOC14_RS25455	COG3689	TIGRFAM TIGR03943 family protein
FOC14_RS25460	COG1607	acyl-coa hydrolase
FOC14_RS25470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC14_RS25485	COG0702	epimerase
FOC14_RS25490	COG2839	Protein conserved in bacteria
FOC14_RS25495	COG1253	flavin adenine dinucleotide binding
FOC14_RS25510	COG1114	Component of the transport system for branched-chain amino acids
FOC14_RS25515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC14_RS25535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS25545	COG1876	peptidase activity
FOC14_RS25555	COG0154	amidase activity
FOC14_RS25560	COG2211	Major facilitator Superfamily
FOC14_RS25580	COG0561	phosphatase activity
FOC14_RS25590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC14_RS25610	COG1819	glycosyl
FOC14_RS25615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC14_RS25620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC14_RS25645	COG0456	acetyltransferase
FOC14_RS25695	COG3874	Sporulation protein YtfJ
FOC14_RS25720	COG2226	methyltransferase
FOC14_RS25745	COG0346	lactoylglutathione lyase activity
FOC14_RS25755	COG0604	alcohol dehydrogenase
FOC14_RS25760	COG1595	DNA-templated transcription, initiation
FOC14_RS25785	COG0386	Belongs to the glutathione peroxidase family
FOC14_RS25790	COG1305	Transglutaminase-like
FOC14_RS25795	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC14_RS25800	COG0714	Associated with various cellular activities
FOC14_RS25815	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC14_RS25820	COG1140	nitrate reductase beta subunit
FOC14_RS25825	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC14_RS25830	COG2181	nitrate reductase activity
FOC14_RS25850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC14_RS25855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC14_RS25860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC14_RS25865	COG0303	'Molybdopterin
FOC14_RS25870	COG0314	molybdopterin synthase activity
FOC14_RS25880	COG2223	nitrite transmembrane transporter activity
FOC14_RS25895	COG1648	precorrin-2 dehydrogenase activity
FOC14_RS25905	COG1587	Uroporphyrinogen-III synthase
FOC14_RS25905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC14_RS25910	COG2146	nitrite reductase [NAD(P)H] activity
FOC14_RS25915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC14_RS25920	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC14_RS25955	COG2359	stage V sporulation protein S
FOC14_RS25970	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC14_RS25985	COG1418	mRNA catabolic process
FOC14_RS25990	COG0488	(ABC) transporter
FOC14_RS26005	COG0629	single-stranded DNA binding
FOC14_RS26020	COG1413	lyase activity
FOC14_RS26035	COG2136	Putative SAM-dependent methyltransferase
FOC14_RS26035	COG2521	methyltransferase
FOC14_RS26040	COG0018	arginyl-trna synthetase
FOC14_RS26065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC14_RS26085	COG0017	Asparaginyl-tRNA synthetase
FOC14_RS26105	COG1674	ftsk spoiiie
FOC14_RS26175	COG1929	Belongs to the glycerate kinase type-1 family
FOC14_RS26180	COG0471	metal ion transport
FOC14_RS26185	COG0745	RESPONSE REGULATOR receiver
FOC14_RS26190	COG3850	Histidine kinase
FOC14_RS26190	COG5002	protein histidine kinase activity
FOC14_RS26205	COG0733	neurotransmitter:sodium symporter activity
FOC14_RS26230	COG2610	gluconate transmembrane transporter activity
FOC14_RS26235	COG1454	alcohol dehydrogenase
FOC14_RS26240	COG1794	racemase activity, acting on amino acids and derivatives
FOC14_RS26250	COG0456	acetyltransferase
FOC14_RS26265	COG1131	(ABC) transporter
FOC14_RS26280	COG0546	phosphoglycolate phosphatase activity
FOC14_RS26300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC14_RS26315	COG0768	penicillin binding
FOC14_RS26320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC14_RS26325	COG0204	Acyl-transferase
FOC14_RS26330	COG1272	protein, Hemolysin III
FOC14_RS26340	COG0805	protein transport
FOC14_RS26350	COG1307	EDD domain protein, DegV family
FOC14_RS26355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC14_RS26360	COG1999	signal sequence binding
FOC14_RS26365	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC14_RS26370	COG0367	asparagine synthase
FOC14_RS26385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC14_RS26390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC14_RS26415	COG1051	belongs to the nudix hydrolase family
FOC14_RS26425	COG0668	transmembrane transport
FOC14_RS26430	COG2203	Gaf domain
FOC14_RS26430	COG4585	Histidine kinase
FOC14_RS26435	COG2197	response regulator
FOC14_RS26445	COG1064	alcohol dehydrogenase
FOC14_RS26470	COG1070	Carbohydrate kinase
FOC14_RS26505	COG1125	glycine betaine transport
FOC14_RS26505	COG0517	IMP dehydrogenase activity
FOC14_RS26510	COG1174	glycine betaine transport
FOC14_RS26545	COG1253	flavin adenine dinucleotide binding
FOC14_RS26550	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS26555	COG5506	Protein of unknown function (DUF1694)
FOC14_RS26570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC14_RS26575	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC14_RS26580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC14_RS26585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC14_RS26590	COG0456	acetyltransferase
FOC14_RS26595	COG3829	transcription factor binding
FOC14_RS26600	COG1509	lysine 2,3-aminomutase activity
FOC14_RS26640	COG4326	sporulation control protein
FOC14_RS26645	COG0671	phosphoesterase, PA-phosphatase related
FOC14_RS26650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC14_RS26655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC14_RS26685	COG1715	Restriction endonuclease
FOC14_RS26685	COG1787	Restriction endonuclease
FOC14_RS26775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC14_RS26815	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC14_RS26815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC14_RS26820	COG2814	Major facilitator Superfamily
FOC14_RS26825	COG4841	protein insertion into membrane
FOC14_RS26830	COG0372	Belongs to the citrate synthase family
FOC14_RS26835	COG2079	MmgE PrpD family protein
FOC14_RS26840	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC14_RS26845	COG1960	acyl-CoA dehydrogenase activity
FOC14_RS26850	COG2084	Dehydrogenase
FOC14_RS26855	COG1012	belongs to the aldehyde dehydrogenase family
FOC14_RS26860	COG1280	lysine exporter protein (LysE YggA)
FOC14_RS26865	COG1024	Enoyl-CoA hydratase
FOC14_RS26880	COG0420	3'-5' exonuclease activity
FOC14_RS26885	COG0419	ATPase involved in DNA repair
FOC14_RS26905	COG2223	nitrite transmembrane transporter activity
FOC14_RS26910	COG1028	Short-chain dehydrogenase reductase Sdr
FOC14_RS26915	COG1169	isochorismate synthase
FOC14_RS26920	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC14_RS26925	COG3433	isochorismatase activity
FOC14_RS26925	COG1535	isochorismatase
FOC14_RS26930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC14_RS26935	COG3251	PFAM MbtH domain protein
FOC14_RS26940	COG2814	Major facilitator Superfamily
FOC14_RS26955	COG0776	regulation of translation
FOC14_RS26965	COG2318	DinB family
FOC14_RS26975	COG1115	amino acid carrier protein
FOC14_RS26990	COG2329	Antibiotic biosynthesis monooxygenase
FOC14_RS26995	COG1187	pseudouridine synthase activity
FOC14_RS27000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC14_RS27015	COG0596	Alpha beta hydrolase
FOC14_RS27020	COG2814	Major facilitator Superfamily
FOC14_RS27040	COG2226	methyltransferase