locus-tag	class	description
C3496_RS00010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3496_RS00015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3496_RS00015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C3496_RS00025	COG2244	polysaccharide biosynthetic process
C3496_RS00030	COG2323	membrane
C3496_RS00040	COG1862	Preprotein translocase
C3496_RS00070	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C3496_RS00080	COG0697	spore germination
C3496_RS00085	COG0640	Transcriptional regulator
C3496_RS00110	COG0157	Belongs to the NadC ModD family
C3496_RS00115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C3496_RS00120	COG1104	cysteine desulfurase activity
C3496_RS00125	COG1827	regulation of RNA biosynthetic process
C3496_RS00130	COG2258	MOSC domain
C3496_RS00135	COG0077	Prephenate dehydratase
C3496_RS00140	COG0577	efflux transmembrane transporter activity
C3496_RS00145	COG0577	efflux transmembrane transporter activity
C3496_RS00150	COG1136	(ABC) transporter
C3496_RS00155	COG5002	protein histidine kinase activity
C3496_RS00160	COG0745	RESPONSE REGULATOR receiver
C3496_RS00170	COG3290	protein histidine kinase activity
C3496_RS00180	COG2868	ribosomal protein
C3496_RS00190	COG1530	ribonuclease E activity
C3496_RS00195	COG1994	Peptidase M50
C3496_RS00200	COG0739	heme binding
C3496_RS00205	COG2894	cell division
C3496_RS00225	COG1077	Cell shape determining protein MreB Mrl
C3496_RS00245	COG0285	dihydrofolate synthase activity
C3496_RS00250	COG0525	valine-tRNA ligase activity
C3496_RS00260	COG1388	LysM domain
C3496_RS00270	COG0113	porphobilinogen synthase activity
C3496_RS00275	COG1587	Uroporphyrinogen-III synthase
C3496_RS00285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3496_RS00295	COG1846	Transcriptional regulator
C3496_RS00300	COG1764	response to oxidative stress
C3496_RS00315	COG1067	ATP-dependent peptidase activity
C3496_RS00315	COG0470	DNA polymerase III
C3496_RS00360	COG0622	Phosphoesterase
C3496_RS00375	COG5401	PFAM Sporulation and spore germination
C3496_RS00395	COG1309	transcriptional regulator
C3496_RS00410	COG2197	response regulator
C3496_RS00445	COG0640	Transcriptional regulator
C3496_RS00455	COG0798	PFAM Bile acid sodium symporter
C3496_RS00470	COG0803	Belongs to the bacterial solute-binding protein 9 family
C3496_RS00475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3496_RS00480	COG1121	(ABC) transporter
C3496_RS00495	COG1999	signal sequence binding
C3496_RS00500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3496_RS00505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C3496_RS00535	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C3496_RS00535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C3496_RS00545	COG2197	response regulator
C3496_RS00550	COG2233	PERMEase
C3496_RS00555	COG0402	S-adenosylhomocysteine deaminase activity
C3496_RS00565	COG1396	sequence-specific DNA binding
C3496_RS00570	COG0697	spore germination
C3496_RS00580	COG1959	2 iron, 2 sulfur cluster binding
C3496_RS00585	COG1668	transmembrane transport
C3496_RS00590	COG4152	abc transporter atp-binding protein
C3496_RS00595	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C3496_RS00600	COG1360	Flagellar Motor Protein
C3496_RS00605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3496_RS00610	COG1876	peptidase activity
C3496_RS00615	COG0824	Thioesterase
C3496_RS00620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C3496_RS00625	COG1053	succinate dehydrogenase
C3496_RS00630	COG2009	succinate dehydrogenase
C3496_RS00635	COG1719	4-vinyl reductase, 4VR
C3496_RS00645	COG3118	belongs to the thioredoxin family
C3496_RS00650	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C3496_RS00655	COG2086	electron transfer activity
C3496_RS00660	COG1024	Enoyl-CoA hydratase
C3496_RS00665	COG1309	transcriptional regulator
C3496_RS00670	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_RS00680	COG2318	DinB family
C3496_RS00705	COG1131	(ABC) transporter
C3496_RS00710	COG2205	protein histidine kinase activity
C3496_RS00715	COG0745	RESPONSE REGULATOR receiver
C3496_RS00725	COG4895	conserved protein (DUF2196)
C3496_RS00730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C3496_RS00745	COG4509	Sortase family
C3496_RS00750	COG1120	ATPase activity
C3496_RS00765	COG5386	Cell surface protein
C3496_RS00770	COG5386	Cell surface protein
C3496_RS00775	COG1114	Component of the transport system for branched-chain amino acids
C3496_RS00780	COG1187	pseudouridine synthase activity
C3496_RS00790	COG1796	DNA polymerase
C3496_RS00790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3496_RS00795	COG1286	toxin biosynthetic process
C3496_RS00840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3496_RS00850	COG1418	mRNA catabolic process
C3496_RS00860	COG2814	Major facilitator Superfamily
C3496_RS00865	COG1566	PFAM secretion protein HlyD family protein
C3496_RS00870	COG1309	transcriptional regulator
C3496_RS00875	COG1363	Peptidase, m42
C3496_RS00900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C3496_RS00910	COG1484	DNA-dependent DNA replication
C3496_RS00915	COG3611	Membrane attachment protein
C3496_RS00925	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C3496_RS00930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3496_RS00935	COG0237	dephospho-CoA kinase activity
C3496_RS00940	COG1971	Probably functions as a manganese efflux pump
C3496_RS00950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3496_RS00950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3496_RS00955	COG5002	protein histidine kinase activity
C3496_RS00960	COG0745	RESPONSE REGULATOR receiver
C3496_RS00980	COG0538	isocitrate dehydrogenase activity
C3496_RS00985	COG0372	Belongs to the citrate synthase family
C3496_RS00995	COG0628	permease
C3496_RS01000	COG3030	protein affecting phage T7 exclusion by the F plasmid
C3496_RS01025	COG1725	Transcriptional regulator
C3496_RS01030	COG0281	malic enzyme
C3496_RS01035	COG0587	DNA-directed DNA polymerase activity
C3496_RS01050	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C3496_RS01070	COG4109	DRTGG domain
C3496_RS01085	COG0006	proline dipeptidase activity
C3496_RS01130	COG0662	Cupin 2, conserved barrel domain protein
C3496_RS01140	COG1476	TRANSCRIPTIONal
C3496_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS01160	COG0589	response to stress
C3496_RS01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS01220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C3496_RS01225	COG0827	DNA restriction-modification system
C3496_RS01230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C3496_RS01235	COG3874	Sporulation protein YtfJ
C3496_RS01250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C3496_RS01260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3496_RS01275	COG1104	cysteine desulfurase activity
C3496_RS01285	COG0583	DNA-binding transcription factor activity
C3496_RS01290	COG0697	spore germination
C3496_RS01295	COG1309	transcriptional regulator
C3496_RS01300	COG1956	GAF domain-containing protein
C3496_RS01305	COG0626	cystathionine gamma-synthase activity
C3496_RS01335	COG1595	DNA-templated transcription, initiation
C3496_RS01350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3496_RS01355	COG0454	-acetyltransferase
C3496_RS01360	COG0517	IMP dehydrogenase activity
C3496_RS01365	COG0123	including yeast histone deacetylase and acetoin utilization protein
C3496_RS01380	COG0745	RESPONSE REGULATOR receiver
C3496_RS01390	COG0666	response to abiotic stimulus
C3496_RS01425	COG1609	Transcriptional regulator
C3496_RS01435	COG4851	CamS sex pheromone cAM373 precursor
C3496_RS01440	COG3118	belongs to the thioredoxin family
C3496_RS01450	COG2309	aminopeptidase activity
C3496_RS01470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS01490	COG1674	ftsk spoiiie
C3496_RS01505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_RS01515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_RS01520	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C3496_RS01525	COG1363	Peptidase, m42
C3496_RS01535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS01550	COG0510	thiamine kinase activity
C3496_RS01555	COG1523	belongs to the glycosyl hydrolase 13 family
C3496_RS01565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3496_RS01570	COG1349	DNA-binding transcription factor activity
C3496_RS01575	COG1187	pseudouridine synthase activity
C3496_RS01580	COG2244	polysaccharide biosynthetic process
C3496_RS01585	COG2081	HI0933 family
C3496_RS01590	COG2814	Major facilitator Superfamily
C3496_RS01600	COG3832	glyoxalase III activity
C3496_RS01620	COG1329	Transcriptional regulator
C3496_RS01645	COG0314	molybdopterin synthase activity
C3496_RS01660	COG1763	Mo-molybdopterin cofactor biosynthetic process
C3496_RS01665	COG0303	'Molybdopterin
C3496_RS01675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_RS01680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3496_RS01700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_RS01710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C3496_RS01750	COG2814	Major facilitator Superfamily
C3496_RS01755	COG0475	glutathione-regulated potassium exporter activity
C3496_RS01760	COG0490	domain, Protein
C3496_RS01765	COG0582	viral genome integration into host DNA
C3496_RS01775	COG1136	(ABC) transporter
C3496_RS01795	COG1242	4 iron, 4 sulfur cluster binding
C3496_RS01800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C3496_RS01815	COG1794	racemase activity, acting on amino acids and derivatives
C3496_RS01835	COG2267	carboxylic ester hydrolase activity
C3496_RS01840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C3496_RS01845	COG0671	phosphoesterase, PA-phosphatase related
C3496_RS01850	COG0438	transferase activity, transferring glycosyl groups
C3496_RS01860	COG0521	Mo-molybdopterin cofactor biosynthetic process
C3496_RS01875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS01920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3496_RS01925	COG5002	protein histidine kinase activity
C3496_RS01930	COG4191	Histidine kinase
C3496_RS01935	COG2267	carboxylic ester hydrolase activity
C3496_RS01955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3496_RS01960	COG1116	anion transmembrane transporter activity
C3496_RS01965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_RS01985	COG0494	nUDIX hydrolase
C3496_RS02015	COG0288	reversible hydration of carbon dioxide
C3496_RS02020	COG1271	oxidase subunit
C3496_RS02025	COG1294	oxidase, subunit
C3496_RS02045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS02070	COG1842	Phage shock protein A
C3496_RS02115	COG5002	protein histidine kinase activity
C3496_RS02120	COG0745	RESPONSE REGULATOR receiver
C3496_RS02145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3496_RS02150	COG1597	lipid kinase activity
C3496_RS02165	COG0577	efflux transmembrane transporter activity
C3496_RS02170	COG1136	(ABC) transporter
C3496_RS02195	COG0586	Pfam SNARE associated Golgi protein
C3496_RS02205	COG4977	sequence-specific DNA binding
C3496_RS02215	COG0577	efflux transmembrane transporter activity
C3496_RS02220	COG1136	(ABC) transporter
C3496_RS02225	COG3708	Transcriptional regulator
C3496_RS02225	COG2207	Transcriptional regulator
C3496_RS02235	COG1131	(ABC) transporter
C3496_RS02240	COG5658	integral membrane protein
C3496_RS02245	COG0640	Transcriptional regulator
C3496_RS02250	COG0745	RESPONSE REGULATOR receiver
C3496_RS02255	COG2205	protein histidine kinase activity
C3496_RS02260	COG0577	efflux transmembrane transporter activity
C3496_RS02265	COG0577	efflux transmembrane transporter activity
C3496_RS02270	COG1136	(ABC) transporter
C3496_RS02275	COG0577	efflux transmembrane transporter activity
C3496_RS02290	COG2188	Transcriptional regulator
C3496_RS02310	COG3964	amidohydrolase
C3496_RS02330	COG4948	Mandelate Racemase Muconate Lactonizing
C3496_RS02340	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C3496_RS02345	COG0596	Alpha beta hydrolase
C3496_RS02355	COG1169	isochorismate synthase
C3496_RS02360	COG1575	Belongs to the MenA family. Type 1 subfamily
C3496_RS02365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C3496_RS02385	COG0058	SHG alpha-glucan phosphorylase activity
C3496_RS02395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C3496_RS02520	COG0544	peptidyl-prolyl cis-trans isomerase activity
C3496_RS02555	COG1285	pathogenesis
C3496_RS02560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3496_RS02575	COG2155	Conserved Protein
C3496_RS02580	COG1098	S1 RNA binding domain
C3496_RS02585	COG0436	Aminotransferase
C3496_RS02590	COG1522	sequence-specific DNA binding
C3496_RS02595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3496_RS02600	COG2267	carboxylic ester hydrolase activity
C3496_RS02610	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C3496_RS02630	COG5018	Exonuclease
C3496_RS02635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3496_RS02655	COG2050	protein possibly involved in aromatic compounds catabolism
C3496_RS02665	COG1268	BioY protein
C3496_RS02675	COG0297	glycogen (starch) synthase activity
C3496_RS02695	COG4485	Bacterial membrane protein, YfhO
C3496_RS02700	COG2246	polysaccharide biosynthetic process
C3496_RS02705	COG0463	Glycosyl transferase, family 2
C3496_RS02710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C3496_RS02715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C3496_RS02735	COG3584	3D domain protein
C3496_RS02750	COG1252	NADH dehydrogenase
C3496_RS02765	COG3708	Transcriptional regulator
C3496_RS02780	COG1683	Conserved Protein
C3496_RS02790	COG0316	Belongs to the HesB IscA family
C3496_RS02805	COG1252	NADH dehydrogenase
C3496_RS02820	COG0390	transport system, permease component
C3496_RS02825	COG2824	Alkylphosphonate utilization operon protein PhnA
C3496_RS02845	COG4837	Protein of unknown function (DUF1462)
C3496_RS02850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C3496_RS02860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3496_RS02865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C3496_RS02880	COG1136	(ABC) transporter
C3496_RS02880	COG0577	efflux transmembrane transporter activity
C3496_RS02885	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_RS02895	COG0647	UMP catabolic process
C3496_RS02905	COG2445	Protein of unknown function DUF86
C3496_RS02910	COG1494	fructose-1,6-bisphosphatase
C3496_RS02925	COG4470	Protein conserved in bacteria
C3496_RS02935	COG0789	Transcriptional regulator
C3496_RS02940	COG4377	Putative membrane peptidase family (DUF2324)
C3496_RS02965	COG0739	heme binding
C3496_RS02975	COG3377	Domain of unknown function (DUF1805)
C3496_RS02980	COG0737	Belongs to the 5'-nucleotidase family
C3496_RS02985	COG0719	Fe-S assembly protein
C3496_RS02990	COG0822	iron-sulfur transferase activity
C3496_RS02995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C3496_RS03000	COG0719	Fe-S assembly protein
C3496_RS03005	COG0396	ATPase activity
C3496_RS03010	COG1464	Belongs to the NlpA lipoprotein family
C3496_RS03015	COG1464	Belongs to the NlpA lipoprotein family
C3496_RS03020	COG2011	ABC-type metal ion transport system permease component
C3496_RS03035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_RS03040	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C3496_RS03055	COG1393	Belongs to the ArsC family
C3496_RS03105	COG1309	transcriptional regulator
C3496_RS03110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS03115	COG1960	acyl-CoA dehydrogenase activity
C3496_RS03120	COG0183	Belongs to the thiolase family
C3496_RS03125	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3496_RS03125	COG1024	Enoyl-CoA hydratase
C3496_RS03135	COG1686	Belongs to the peptidase S11 family
C3496_RS03150	COG0011	TIGRFAM Protein of
C3496_RS03155	COG0840	transmembrane signaling receptor activity
C3496_RS03175	COG2814	Major facilitator Superfamily
C3496_RS03180	COG0531	amino acid
C3496_RS03195	COG0706	membrane insertase activity
C3496_RS03205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS03245	COG0586	Pfam SNARE associated Golgi protein
C3496_RS03255	COG1376	ErfK ybiS ycfS ynhG family protein
C3496_RS03260	COG0745	RESPONSE REGULATOR receiver
C3496_RS03265	COG5002	protein histidine kinase activity
C3496_RS03290	COG0840	transmembrane signaling receptor activity
C3496_RS03295	COG2151	metal-sulfur cluster biosynthetic enzyme
C3496_RS03300	COG3227	Zinc metalloprotease (Elastase)
C3496_RS03305	COG1741	Belongs to the pirin family
C3496_RS03320	COG0586	Pfam SNARE associated Golgi protein
C3496_RS03325	COG0475	glutathione-regulated potassium exporter activity
C3496_RS03330	COG0490	domain, Protein
C3496_RS03335	COG1115	amino acid carrier protein
C3496_RS03340	COG0783	Belongs to the Dps family
C3496_RS03355	COG1611	Belongs to the LOG family
C3496_RS03375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS03380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS03385	COG1115	amino acid carrier protein
C3496_RS03390	COG1115	amino acid carrier protein
C3496_RS03395	COG2910	NAD(P)H-binding
C3496_RS03410	COG0656	L-ascorbic acid biosynthetic process
C3496_RS03415	COG2814	Major facilitator Superfamily
C3496_RS03420	COG1733	regulation of RNA biosynthetic process
C3496_RS03430	COG1252	NADH dehydrogenase
C3496_RS03435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C3496_RS03450	COG0840	transmembrane signaling receptor activity
C3496_RS03450	COG3290	protein histidine kinase activity
C3496_RS03460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C3496_RS03480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS03535	COG0557	exoribonuclease II activity
C3496_RS03540	COG1647	Serine aminopeptidase, S33
C3496_RS03545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3496_RS03550	COG1346	cytolysis
C3496_RS03585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C3496_RS03600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C3496_RS03625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_RS03640	COG2323	membrane
C3496_RS03650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_RS03660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C3496_RS03670	COG1051	belongs to the nudix hydrolase family
C3496_RS03680	COG0492	ferredoxin-NADP+ reductase activity
C3496_RS03685	COG0457	Tetratricopeptide repeat
C3496_RS03690	COG0110	maltose O-acetyltransferase activity
C3496_RS03710	COG1950	PFAM Membrane protein of
C3496_RS03720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C3496_RS03740	COG0789	Transcriptional regulator
C3496_RS03765	COG2855	membrane
C3496_RS03770	COG0583	DNA-binding transcription factor activity
C3496_RS03780	COG0655	NAD(P)H dehydrogenase (quinone) activity
C3496_RS03785	COG0488	(ABC) transporter
C3496_RS03795	COG1132	(ABC) transporter
C3496_RS03800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3496_RS03805	COG3409	Peptidoglycan-binding domain 1 protein
C3496_RS03805	COG0793	Belongs to the peptidase S41A family
C3496_RS03810	COG2177	Part of the ABC transporter FtsEX involved in
C3496_RS03815	COG2884	Cell division ATP-binding protein ftsE
C3496_RS03835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C3496_RS03840	COG1278	Cold shock
C3496_RS03845	COG1040	competence protein
C3496_RS03850	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C3496_RS03855	COG1388	LysM domain
C3496_RS03855	COG0791	NLP P60 protein
C3496_RS03860	COG1733	regulation of RNA biosynthetic process
C3496_RS03865	COG1307	EDD domain protein, DegV family
C3496_RS03870	COG1739	Uncharacterized protein family UPF0029
C3496_RS03875	COG1316	TRANSCRIPTIONal
C3496_RS03880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3496_RS03885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C3496_RS03890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C3496_RS03900	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C3496_RS03900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C3496_RS03920	COG1486	melibiose metabolic process
C3496_RS03925	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3496_RS03930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3496_RS03940	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C3496_RS03950	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3496_RS03960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3496_RS03965	COG1301	dicarboxylic acid transport
C3496_RS03975	COG0346	lactoylglutathione lyase activity
C3496_RS03980	COG1511	domain protein
C3496_RS03985	COG0583	DNA-binding transcription factor activity
C3496_RS03990	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C3496_RS04000	COG1271	oxidase subunit
C3496_RS04005	COG1294	oxidase, subunit
C3496_RS04010	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3496_RS04020	COG1620	l-lactate permease
C3496_RS04030	COG2389	metal-binding protein
C3496_RS04040	COG1368	sulfuric ester hydrolase activity
C3496_RS04050	COG1388	LysM domain
C3496_RS04050	COG0791	NLP P60 protein
C3496_RS04055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS04065	COG1215	transferase activity, transferring glycosyl groups
C3496_RS04070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3496_RS04075	COG1388	LysM domain
C3496_RS04075	COG3584	3D domain protein
C3496_RS04085	COG4715	Zinc finger, swim domain protein
C3496_RS04090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3496_RS04130	COG0577	efflux transmembrane transporter activity
C3496_RS04135	COG1136	(ABC) transporter
C3496_RS04170	COG5002	protein histidine kinase activity
C3496_RS04175	COG0745	RESPONSE REGULATOR receiver
C3496_RS04180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3496_RS04200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C3496_RS04210	COG1134	teichoic acid transport
C3496_RS04215	COG1682	transport, permease protein
C3496_RS04220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C3496_RS04265	COG1609	Transcriptional regulator
C3496_RS04280	COG0739	heme binding
C3496_RS04295	COG3279	Response regulator of the LytR AlgR family
C3496_RS04300	COG2385	sporulation resulting in formation of a cellular spore
C3496_RS04315	COG4836	Membrane
C3496_RS04320	COG1007	ATP synthesis coupled electron transport
C3496_RS04325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3496_RS04330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3496_RS04340	COG0839	Belongs to the complex I subunit 6 family
C3496_RS04360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C3496_RS04375	COG3300	MHYT domain
C3496_RS04375	COG5001	Diguanylate cyclase
C3496_RS04425	COG0356	it plays a direct role in the translocation of protons across the membrane
C3496_RS04460	COG0698	ribose 5-phosphate isomerase
C3496_RS04470	COG2190	(PTS) system
C3496_RS04475	COG2259	Doxx family
C3496_RS04480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3496_RS04500	COG0009	L-threonylcarbamoyladenylate synthase
C3496_RS04515	COG2890	protein-(glutamine-N5) methyltransferase activity
C3496_RS04535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C3496_RS04540	COG1494	fructose-1,6-bisphosphatase
C3496_RS04560	COG4821	SIS domain
C3496_RS04580	COG1960	acyl-CoA dehydrogenase activity
C3496_RS04585	COG1960	acyl-CoA dehydrogenase activity
C3496_RS04590	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3496_RS04595	COG0183	Belongs to the thiolase family
C3496_RS04600	COG2181	nitrate reductase activity
C3496_RS04600	COG0247	lactate metabolic process
C3496_RS04605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_RS04615	COG5001	Diguanylate cyclase
C3496_RS04615	COG3300	MHYT domain
C3496_RS04635	COG2197	response regulator
C3496_RS04640	COG4585	Histidine kinase
C3496_RS04645	COG0842	Transport permease protein
C3496_RS04650	COG1131	(ABC) transporter
C3496_RS04655	COG0024	Methionine aminopeptidase
C3496_RS04665	COG2234	aminopeptidase activity
C3496_RS04685	COG1595	DNA-templated transcription, initiation
C3496_RS04695	COG4506	Protein conserved in bacteria
C3496_RS04700	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_RS04715	COG0010	Belongs to the arginase family
C3496_RS04725	COG2814	Major facilitator Superfamily
C3496_RS04730	COG0789	Transcriptional regulator
C3496_RS04735	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_RS04740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_RS04750	COG1994	Peptidase M50
C3496_RS04760	COG1078	dGTPase activity
C3496_RS04765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS04770	COG1120	ATPase activity
C3496_RS04775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS04780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS04800	COG0095	Lipoate-protein ligase
C3496_RS04805	COG0280	phosphate acetyltransferase
C3496_RS04820	COG3773	Cell wall hydrolase
C3496_RS04830	COG2363	Small membrane protein
C3496_RS04840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C3496_RS04845	COG2233	PERMEase
C3496_RS04850	COG0561	phosphatase activity
C3496_RS04855	COG2814	Major facilitator Superfamily
C3496_RS04865	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3496_RS04870	COG1131	(ABC) transporter
C3496_RS04875	COG2755	lipolytic protein G-D-S-L family
C3496_RS04880	COG1609	Transcriptional regulator
C3496_RS04890	COG0460	homoserine dehydrogenase
C3496_RS04900	COG2873	o-acetylhomoserine
C3496_RS04910	COG1011	Hydrolase
C3496_RS04915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3496_RS04925	COG2197	response regulator
C3496_RS04930	COG4585	Histidine kinase
C3496_RS04930	COG2203	Gaf domain
C3496_RS04935	COG0351	phosphomethylpyrimidine kinase
C3496_RS04940	COG3706	GGDEF domain
C3496_RS04945	COG2879	small protein
C3496_RS04950	COG1966	Carbon starvation protein
C3496_RS04955	COG3279	Response regulator of the LytR AlgR family
C3496_RS04960	COG0477	Major facilitator Superfamily
C3496_RS04985	COG0840	transmembrane signaling receptor activity
C3496_RS04995	COG1607	acyl-coa hydrolase
C3496_RS05010	COG0488	(ABC) transporter
C3496_RS05020	COG1309	transcriptional regulator
C3496_RS05025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3496_RS05030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3496_RS05030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3496_RS05035	COG0628	permease
C3496_RS05050	COG3279	Response regulator of the LytR AlgR family
C3496_RS05055	COG3275	phosphorelay sensor kinase activity
C3496_RS05060	COG2814	Major facilitator Superfamily
C3496_RS05065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3496_RS05070	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C3496_RS05075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3496_RS05095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C3496_RS05100	COG1272	protein, Hemolysin III
C3496_RS05120	COG1164	Oligoendopeptidase f
C3496_RS05140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3496_RS05145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C3496_RS05150	COG4853	Protein conserved in bacteria
C3496_RS05155	COG4863	YycH protein
C3496_RS05160	COG5002	protein histidine kinase activity
C3496_RS05165	COG0745	RESPONSE REGULATOR receiver
C3496_RS05195	COG0305	Participates in initiation and elongation during chromosome replication
C3496_RS05205	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C3496_RS05210	COG4241	membrane
C3496_RS05220	COG0629	single-stranded DNA binding
C3496_RS05230	COG0012	GTP binding
C3496_RS05235	COG4481	Protein conserved in bacteria
C3496_RS05240	COG0668	transmembrane transport
C3496_RS05250	COG1475	DNA binding
C3496_RS05255	COG1192	Involved in chromosome partitioning
C3496_RS05280	COG1847	R3H domain protein
C3496_RS05285	COG0706	membrane insertase activity
C3496_RS05295	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C3496_RS05305	COG0592	DNA-directed DNA polymerase activity
C3496_RS05310	COG2501	S4 domain
C3496_RS05320	COG0187	DNA topoisomerase II activity
C3496_RS05325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3496_RS05360	COG0516	GMP reductase activity
C3496_RS05360	COG0517	IMP dehydrogenase activity
C3496_RS05365	COG1686	Belongs to the peptidase S11 family
C3496_RS05395	COG1428	Deoxynucleoside kinase
C3496_RS05400	COG1428	Deoxynucleoside kinase
C3496_RS05405	COG1335	isochorismatase
C3496_RS05410	COG0590	tRNA wobble adenosine to inosine editing
C3496_RS05420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C3496_RS05475	COG1982	Orn Lys Arg decarboxylase major
C3496_RS05485	COG0470	DNA polymerase III
C3496_RS05490	COG1774	PSP1 C-terminal conserved region
C3496_RS05500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C3496_RS05515	COG2002	toxin-antitoxin pair type II binding
C3496_RS05520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_RS05520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_RS05525	COG0084	hydrolase, TatD family'
C3496_RS05530	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C3496_RS05545	COG4466	Protein conserved in bacteria
C3496_RS05560	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C3496_RS05565	COG0251	oxidation-reduction process
C3496_RS05595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C3496_RS05600	COG2002	toxin-antitoxin pair type II binding
C3496_RS05605	COG2244	polysaccharide biosynthetic process
C3496_RS05610	COG3956	TIGRFAM MazG family protein
C3496_RS05615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C3496_RS05635	COG1098	S1 RNA binding domain
C3496_RS05650	COG2208	phosphoserine phosphatase activity
C3496_RS05660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C3496_RS05665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C3496_RS05680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3496_RS05685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C3496_RS05690	COG0512	Glutamine amidotransferase of anthranilate synthase
C3496_RS05695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_RS05700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C3496_RS05705	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C3496_RS05710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C3496_RS05715	COG1396	sequence-specific DNA binding
C3496_RS05720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3496_RS05810	COG3880	PFAM UvrB UvrC protein
C3496_RS05820	COG0542	response to heat
C3496_RS05825	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C3496_RS05835	COG4956	integral membrane protein (PIN domain superfamily)
C3496_RS05855	COG1045	serine acetyltransferase
C3496_RS05870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C3496_RS05875	COG3688	RNA-binding protein containing a PIN domain
C3496_RS05890	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C3496_RS05895	COG0250	Participates in transcription elongation, termination and antitermination
C3496_RS05900	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C3496_RS05920	COG2813	Specifically methylates the guanine in position
C3496_RS05935	COG1358	cellular component organization or biogenesis
C3496_RS06005	COG0255	Belongs to the universal ribosomal protein uL29 family
C3496_RS06065	COG0201	protein transport
C3496_RS06075	COG0024	Methionine aminopeptidase
C3496_RS06085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C3496_RS06120	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C3496_RS06145	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_RS06150	COG0489	protein tyrosine kinase activity
C3496_RS06160	COG2194	sulfuric ester hydrolase activity
C3496_RS06165	COG0726	polysaccharide deacetylase
C3496_RS06245	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C3496_RS06250	COG4856	YbbR-like protein
C3496_RS06345	COG0596	Alpha beta hydrolase
C3496_RS06365	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C3496_RS06370	COG4946	Tricorn protease homolog
C3496_RS06370	COG1506	peptidase
C3496_RS06370	COG0823	Involved in the tonB-independent uptake of proteins
C3496_RS06400	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS06405	COG2011	ABC-type metal ion transport system permease component
C3496_RS06415	COG1464	Belongs to the NlpA lipoprotein family
C3496_RS06420	COG0604	alcohol dehydrogenase
C3496_RS06430	COG0277	FAD linked oxidase domain protein
C3496_RS06435	COG2271	Major facilitator Superfamily
C3496_RS06445	COG2814	Major facilitator Superfamily
C3496_RS06460	COG0601	transmembrane transport
C3496_RS06465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_RS06470	COG0444	Belongs to the ABC transporter superfamily
C3496_RS06475	COG4608	Belongs to the ABC transporter superfamily
C3496_RS06480	COG4166	transmembrane transport
C3496_RS06490	COG2207	Transcriptional regulator
C3496_RS06500	COG1309	transcriptional regulator
C3496_RS06510	COG4166	transmembrane transport
C3496_RS06515	COG4166	transmembrane transport
C3496_RS06520	COG0656	L-ascorbic acid biosynthetic process
C3496_RS06525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_RS06540	COG4149	molybdate abc transporter
C3496_RS06545	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3496_RS06550	COG1910	domain protein
C3496_RS06565	COG0697	spore germination
C3496_RS06580	COG0204	Acyl-transferase
C3496_RS06590	COG1609	Transcriptional regulator
C3496_RS06600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS06620	COG5298	Protein conserved in bacteria
C3496_RS06645	COG0488	(ABC) transporter
C3496_RS06650	COG4585	Histidine kinase
C3496_RS06655	COG2197	response regulator
C3496_RS06660	COG1131	(ABC) transporter
C3496_RS06665	COG1511	domain protein
C3496_RS06665	COG0842	Transport permease protein
C3496_RS06670	COG0842	Transport permease protein
C3496_RS06680	COG0747	negative chemotaxis
C3496_RS06685	COG0601	transmembrane transport
C3496_RS06690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_RS06695	COG0444	Belongs to the ABC transporter superfamily
C3496_RS06700	COG4608	Belongs to the ABC transporter superfamily
C3496_RS06705	COG0561	phosphatase activity
C3496_RS06735	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C3496_RS06740	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3496_RS06750	COG0531	amino acid
C3496_RS06765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3496_RS06775	COG4294	response to UV
C3496_RS06780	COG0705	Rhomboid family
C3496_RS06790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C3496_RS06795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3496_RS06800	COG0864	Transcriptional regulator
C3496_RS06805	COG2337	Toxic component of a toxin-antitoxin (TA) module
C3496_RS06810	COG2183	response to ionizing radiation
C3496_RS06905	COG0802	atpase or kinase
C3496_RS06910	COG1214	PFAM Peptidase M22, glycoprotease
C3496_RS06915	COG0456	acetyltransferase
C3496_RS06925	COG0488	(ABC) transporter
C3496_RS06940	COG1266	CAAX protease self-immunity
C3496_RS06960	COG2252	PERMEase
C3496_RS06970	COG5002	protein histidine kinase activity
C3496_RS06995	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3496_RS07070	COG2205	protein histidine kinase activity
C3496_RS07075	COG0745	RESPONSE REGULATOR receiver
C3496_RS07095	COG0697	spore germination
C3496_RS07120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C3496_RS07125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C3496_RS07130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C3496_RS07140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C3496_RS07155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C3496_RS07165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C3496_RS07175	COG0151	Belongs to the GarS family
C3496_RS07200	COG0210	DNA helicase
C3496_RS07210	COG4851	CamS sex pheromone cAM373 precursor
C3496_RS07225	COG1335	isochorismatase
C3496_RS07235	COG2011	ABC-type metal ion transport system permease component
C3496_RS07240	COG1464	Belongs to the NlpA lipoprotein family
C3496_RS07255	COG0003	Pfam Anion-transporting ATPase
C3496_RS07260	COG1846	Transcriptional regulator
C3496_RS07265	COG4682	membrane
C3496_RS07285	COG1597	lipid kinase activity
C3496_RS07290	COG0546	phosphoglycolate phosphatase activity
C3496_RS07295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C3496_RS07305	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS07310	COG2076	Multidrug Resistance protein
C3496_RS07315	COG2309	aminopeptidase activity
C3496_RS07330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS07335	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C3496_RS07340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C3496_RS07345	COG5002	protein histidine kinase activity
C3496_RS07350	COG4807	Protein conserved in bacteria
C3496_RS07375	COG1757	Na H antiporter
C3496_RS07380	COG1473	amidohydrolase
C3496_RS07395	COG0450	alkyl hydroperoxide reductase
C3496_RS07415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS07420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS07425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS07440	COG0166	Belongs to the GPI family
C3496_RS07470	COG5002	protein histidine kinase activity
C3496_RS07490	COG3541	Predicted nucleotidyltransferase
C3496_RS07495	COG2814	Major facilitator Superfamily
C3496_RS07500	COG0723	plastoquinol--plastocyanin reductase activity
C3496_RS07500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_RS07510	COG0765	amino acid transport
C3496_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_RS07525	COG0840	transmembrane signaling receptor activity
C3496_RS07530	COG0366	Alpha amylase catalytic
C3496_RS07535	COG2190	(PTS) system
C3496_RS07535	COG1263	PTS System
C3496_RS07535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_RS07570	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C3496_RS07585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_RS07595	COG1116	anion transmembrane transporter activity
C3496_RS07600	COG0488	(ABC) transporter
C3496_RS07645	COG2270	Major facilitator Superfamily
C3496_RS07670	COG4193	domain, Protein
C3496_RS07680	COG2310	stress, protein
C3496_RS07685	COG2310	stress, protein
C3496_RS07690	COG2310	stress, protein
C3496_RS07695	COG0861	Integral membrane protein TerC family
C3496_RS07705	COG3853	Toxic anion resistance protein (TelA)
C3496_RS07720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C3496_RS07730	COG1295	ribonuclease BN
C3496_RS07735	COG2217	Heavy metal translocating P-type atpase
C3496_RS07740	COG0697	spore germination
C3496_RS07750	COG0681	Belongs to the peptidase S26 family
C3496_RS07760	COG0586	Pfam SNARE associated Golgi protein
C3496_RS07775	COG3871	stress protein (general stress protein 26)
C3496_RS07780	COG0387	Pfam Sodium calcium exchanger
C3496_RS07790	COG0535	radical SAM domain protein
C3496_RS07810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C3496_RS07830	COG3829	transcription factor binding
C3496_RS07840	COG0833	amino acid
C3496_RS07845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3496_RS07875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_RS07875	COG1263	PTS System
C3496_RS07880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_RS07900	COG0463	Glycosyl transferase, family 2
C3496_RS07925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C3496_RS07945	COG1228	amidohydrolase
C3496_RS07950	COG1090	epimerase
C3496_RS07980	COG1988	membrane-bound metal-dependent
C3496_RS07985	COG1194	a g-specific adenine glycosylase
C3496_RS08010	COG1132	(ABC) transporter
C3496_RS08015	COG4129	membrane
C3496_RS08020	COG0067	glutamate synthase
C3496_RS08020	COG0070	glutamate synthase
C3496_RS08020	COG0069	glutamate synthase activity
C3496_RS08030	COG4555	ABC transporter
C3496_RS08050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C3496_RS08055	COG0735	belongs to the Fur family
C3496_RS08170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C3496_RS08175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C3496_RS08185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C3496_RS08195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C3496_RS08205	COG2766	serine protein kinase
C3496_RS08225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C3496_RS08235	COG1585	Membrane protein implicated in regulation of membrane protease activity
C3496_RS08240	COG2268	Band 7 protein
C3496_RS08250	COG3290	protein histidine kinase activity
C3496_RS08255	COG4565	transcriptional regulatory protein
C3496_RS08260	COG2851	Citrate transporter
C3496_RS08285	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C3496_RS08290	COG3842	ATPase activity
C3496_RS08295	COG1175	transmembrane transport
C3496_RS08300	COG0395	ABC-type sugar transport system, permease component
C3496_RS08310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C3496_RS08315	COG0745	RESPONSE REGULATOR receiver
C3496_RS08320	COG5002	protein histidine kinase activity
C3496_RS08330	COG4990	cell redox homeostasis
C3496_RS08340	COG3290	protein histidine kinase activity
C3496_RS08345	COG4565	transcriptional regulatory protein
C3496_RS08350	COG3493	citrate carrier protein
C3496_RS08355	COG0281	malic enzyme
C3496_RS08365	COG0697	spore germination
C3496_RS08370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS08380	COG5002	protein histidine kinase activity
C3496_RS08385	COG0745	RESPONSE REGULATOR receiver
C3496_RS08390	COG0454	-acetyltransferase
C3496_RS08390	COG0456	acetyltransferase
C3496_RS08395	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C3496_RS08400	COG3383	formate dehydrogenase (NAD+) activity
C3496_RS08405	COG2427	Protein of unknown function (DUF1641)
C3496_RS08420	COG0531	amino acid
C3496_RS08425	COG0640	Transcriptional regulator
C3496_RS08430	COG2217	Heavy metal translocating P-type atpase
C3496_RS08435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C3496_RS08450	COG3227	Zinc metalloprotease (Elastase)
C3496_RS08470	COG2720	vancomycin resistance protein
C3496_RS08475	COG1316	TRANSCRIPTIONal
C3496_RS08480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS08485	COG0346	lactoylglutathione lyase activity
C3496_RS08490	COG1253	flavin adenine dinucleotide binding
C3496_RS08495	COG1027	Aspartate ammonia-lyase
C3496_RS08500	COG1620	l-lactate permease
C3496_RS08515	COG3104	oligopeptide transport
C3496_RS08520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS08525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS08530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS08540	COG2226	methyltransferase
C3496_RS08545	COG0156	8-amino-7-oxononanoate synthase activity
C3496_RS08550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3496_RS08555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C3496_RS08565	COG4548	von Willebrand factor, type A
C3496_RS08570	COG0714	Associated with various cellular activities
C3496_RS08575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_RS08595	COG0531	amino acid
C3496_RS08600	COG2188	Transcriptional regulator
C3496_RS08605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_RS08605	COG1263	PTS System
C3496_RS08610	COG0366	Alpha amylase catalytic
C3496_RS08625	COG0697	spore germination
C3496_RS08635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3496_RS08640	COG1115	amino acid carrier protein
C3496_RS08645	COG1126	abc transporter atp-binding protein
C3496_RS08650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_RS08655	COG0765	amino acid transport
C3496_RS08660	COG0765	amino acid transport
C3496_RS08665	COG0833	amino acid
C3496_RS08690	COG2378	regulation of single-species biofilm formation
C3496_RS08695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C3496_RS08700	COG5002	protein histidine kinase activity
C3496_RS08715	COG0659	secondary active sulfate transmembrane transporter activity
C3496_RS08730	COG0747	negative chemotaxis
C3496_RS08740	COG0601	transmembrane transport
C3496_RS08745	COG4608	Belongs to the ABC transporter superfamily
C3496_RS08755	COG2271	Major facilitator Superfamily
C3496_RS08760	COG1846	Transcriptional regulator
C3496_RS08765	COG0477	Major facilitator Superfamily
C3496_RS08770	COG1609	Transcriptional regulator
C3496_RS08775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C3496_RS08790	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3496_RS08795	COG1879	ABC-type sugar transport system periplasmic component
C3496_RS08810	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_RS08820	COG1063	alcohol dehydrogenase
C3496_RS08835	COG3568	Endonuclease Exonuclease Phosphatase
C3496_RS08865	COG0840	transmembrane signaling receptor activity
C3496_RS08870	COG1388	LysM domain
C3496_RS08870	COG3584	3D domain protein
C3496_RS08875	COG1476	TRANSCRIPTIONal
C3496_RS08890	COG3104	oligopeptide transport
C3496_RS08895	COG1114	Component of the transport system for branched-chain amino acids
C3496_RS08910	COG1113	amino acid transport
C3496_RS08915	COG2252	PERMEase
C3496_RS08930	COG2153	protein acetylation
C3496_RS08940	COG0569	domain protein
C3496_RS08940	COG0475	glutathione-regulated potassium exporter activity
C3496_RS08955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C3496_RS08960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C3496_RS08965	COG0833	amino acid
C3496_RS08970	COG4990	cell redox homeostasis
C3496_RS08985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_RS08990	COG0697	spore germination
C3496_RS08995	COG0531	amino acid
C3496_RS09010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3496_RS09015	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3496_RS09020	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C3496_RS09020	COG1918	ferrous iron import across plasma membrane
C3496_RS09025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3496_RS09030	COG0573	inorganic phosphate transmembrane transporter activity
C3496_RS09035	COG0581	inorganic phosphate transmembrane transporter activity
C3496_RS09045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C3496_RS09165	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C3496_RS09185	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3496_RS09190	COG1116	anion transmembrane transporter activity
C3496_RS09195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_RS09200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3496_RS09205	COG0352	thiamine-phosphate diphosphorylase activity
C3496_RS09210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_RS09215	COG2104	thiamine diphosphate biosynthetic process
C3496_RS09225	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_RS09230	COG0351	phosphomethylpyrimidine kinase
C3496_RS09270	COG2205	protein histidine kinase activity
C3496_RS09275	COG2814	Major facilitator Superfamily
C3496_RS09280	COG1846	Transcriptional regulator
C3496_RS09295	COG2252	PERMEase
C3496_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS09320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_RS09360	COG0778	Nitroreductase
C3496_RS09365	COG2719	SpoVR family
C3496_RS09375	COG1414	Transcriptional regulator
C3496_RS09390	COG0446	pyridine nucleotide-disulphide oxidoreductase
C3496_RS09395	COG1937	Protein conserved in bacteria
C3496_RS09400	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_RS09400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_RS09405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_RS09405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS09410	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_RS09415	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_RS09420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_RS09420	COG0425	Belongs to the sulfur carrier protein TusA family
C3496_RS09430	COG2210	Belongs to the sulfur carrier protein TusA family
C3496_RS09435	COG0730	response to heat
C3496_RS09445	COG1316	TRANSCRIPTIONal
C3496_RS09450	COG0604	alcohol dehydrogenase
C3496_RS09470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_RS09470	COG3711	transcriptional antiterminator
C3496_RS09475	COG1447	Phosphotransferase system cellobiose-specific component IIA
C3496_RS09480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C3496_RS09500	COG1388	LysM domain
C3496_RS09500	COG3584	3D domain protein
C3496_RS09505	COG0577	efflux transmembrane transporter activity
C3496_RS09510	COG1136	(ABC) transporter
C3496_RS09520	COG5522	Integral membrane protein (intg_mem_TP0381)
C3496_RS09535	COG0577	efflux transmembrane transporter activity
C3496_RS09540	COG1114	Component of the transport system for branched-chain amino acids
C3496_RS09545	COG3546	catalase activity
C3496_RS09580	COG0586	Pfam SNARE associated Golgi protein
C3496_RS09615	COG0531	amino acid
C3496_RS09620	COG0475	glutathione-regulated potassium exporter activity
C3496_RS09630	COG1737	Transcriptional regulator
C3496_RS09640	COG1263	PTS System
C3496_RS09640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_RS09650	COG2259	Doxx family
C3496_RS09670	COG1522	sequence-specific DNA binding
C3496_RS09685	COG2076	Multidrug Resistance protein
C3496_RS09690	COG1309	transcriptional regulator
C3496_RS09695	COG2814	Major facilitator Superfamily
C3496_RS09700	COG1733	regulation of RNA biosynthetic process
C3496_RS09710	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_RS09715	COG4533	DNA binding
C3496_RS09720	COG2211	Major facilitator Superfamily
C3496_RS09730	COG0693	protein deglycase activity
C3496_RS09735	COG0753	catalase activity
C3496_RS09745	COG0531	amino acid
C3496_RS09750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C3496_RS09760	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS09765	COG1132	(ABC) transporter
C3496_RS09770	COG1132	(ABC) transporter
C3496_RS09775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_RS09780	COG0765	amino acid transport
C3496_RS09785	COG1126	abc transporter atp-binding protein
C3496_RS09800	COG0189	ligase activity
C3496_RS09830	COG0028	Belongs to the TPP enzyme family
C3496_RS09835	COG3527	Alpha-acetolactate decarboxylase
C3496_RS09845	COG0561	phosphatase activity
C3496_RS09860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3496_RS09880	COG0659	secondary active sulfate transmembrane transporter activity
C3496_RS09890	COG1024	Enoyl-CoA hydratase
C3496_RS09905	COG1363	Peptidase, m42
C3496_RS09925	COG3938	Belongs to the proline racemase family
C3496_RS09950	COG0601	transmembrane transport
C3496_RS09955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_RS09960	COG0444	Belongs to the ABC transporter superfamily
C3496_RS09965	COG4608	Belongs to the ABC transporter superfamily
C3496_RS09975	COG0477	Major facilitator Superfamily
C3496_RS09980	COG3290	protein histidine kinase activity
C3496_RS09985	COG4565	transcriptional regulatory protein
C3496_RS09990	COG3181	Tripartite tricarboxylate transporter family receptor
C3496_RS10070	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C3496_RS10080	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C3496_RS10095	COG4978	Transcriptional regulator
C3496_RS10095	COG0789	Transcriptional regulator
C3496_RS10110	COG0305	Participates in initiation and elongation during chromosome replication
C3496_RS10135	COG0477	Major facilitator Superfamily
C3496_RS10185	COG3320	Male sterility
C3496_RS10185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3496_RS10190	COG1309	transcriptional regulator
C3496_RS10200	COG3711	transcriptional antiterminator
C3496_RS10205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_RS10205	COG2190	(PTS) system
C3496_RS10205	COG1263	PTS System
C3496_RS10210	COG2723	6-phospho-beta-galactosidase activity
C3496_RS10220	COG1183	phosphatidylcholine synthase activity
C3496_RS10255	COG2376	Dihydroxyacetone kinase
C3496_RS10265	COG2376	Dihydroxyacetone kinase
C3496_RS10360	COG3237	CsbD-like
C3496_RS10385	COG1191	sigma factor activity
C3496_RS10395	COG2208	phosphoserine phosphatase activity
C3496_RS10400	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C3496_RS10405	COG0784	Response regulator, receiver
C3496_RS10405	COG2198	Histidine kinase
C3496_RS10405	COG2205	protein histidine kinase activity
C3496_RS10450	COG4585	Histidine kinase
C3496_RS10455	COG2197	response regulator
C3496_RS10485	COG0420	3'-5' exonuclease activity
C3496_RS10490	COG4717	serine-type aminopeptidase activity
C3496_RS10525	COG0346	lactoylglutathione lyase activity
C3496_RS10530	COG0346	lactoylglutathione lyase activity
C3496_RS10535	COG0457	Tetratricopeptide repeat
C3496_RS10540	COG2267	carboxylic ester hydrolase activity
C3496_RS10565	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C3496_RS10570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C3496_RS10580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C3496_RS10605	COG0772	Belongs to the SEDS family
C3496_RS10620	COG0477	Major facilitator Superfamily
C3496_RS10625	COG0477	Major facilitator Superfamily
C3496_RS10635	COG3973	AAA domain
C3496_RS10640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3496_RS10660	COG4980	gas vesicle protein
C3496_RS10665	COG0537	adenosine 5'-monophosphoramidase activity
C3496_RS10670	COG1131	(ABC) transporter
C3496_RS10675	COG4473	ABC transporter
C3496_RS10755	COG1309	transcriptional regulator
C3496_RS10760	COG3402	PFAM membrane-flanked domain
C3496_RS10765	COG3428	Bacterial PH domain
C3496_RS10785	COG3402	PFAM membrane-flanked domain
C3496_RS10790	COG3428	Bacterial PH domain
C3496_RS10795	COG2329	Antibiotic biosynthesis monooxygenase
C3496_RS10800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_RS10815	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C3496_RS10850	COG1309	transcriptional regulator
C3496_RS10855	COG1511	domain protein
C3496_RS10870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS10880	COG2378	regulation of single-species biofilm formation
C3496_RS10885	COG1609	Transcriptional regulator
C3496_RS10895	COG1234	tRNA 3'-trailer cleavage
C3496_RS10900	COG0095	Lipoate-protein ligase
C3496_RS10910	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_RS10940	COG1408	metallophosphoesterase
C3496_RS10950	COG1078	dGTPase activity
C3496_RS10960	COG0477	Major facilitator Superfamily
C3496_RS10970	COG1595	DNA-templated transcription, initiation
C3496_RS10975	COG3708	Transcriptional regulator
C3496_RS10975	COG2207	Transcriptional regulator
C3496_RS10990	COG2205	protein histidine kinase activity
C3496_RS10995	COG0745	RESPONSE REGULATOR receiver
C3496_RS11020	COG0501	Belongs to the peptidase M48B family
C3496_RS11025	COG0840	transmembrane signaling receptor activity
C3496_RS11030	COG0697	spore germination
C3496_RS11040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C3496_RS11045	COG2224	Isocitrate lyase
C3496_RS11070	COG4903	ComK protein
C3496_RS11075	COG0398	Pfam SNARE associated Golgi protein
C3496_RS11090	COG1074	ATP-dependent DNA helicase activity
C3496_RS11135	COG0179	Fumarylacetoacetate (FAA) hydrolase
C3496_RS11160	COG0367	asparagine synthase
C3496_RS11170	COG0753	catalase activity
C3496_RS11175	COG0004	ammonium transporteR
C3496_RS11195	COG2996	Protein conserved in bacteria
C3496_RS11200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3496_RS11210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS11225	COG0561	phosphatase activity
C3496_RS11235	COG0542	response to heat
C3496_RS11245	COG2267	carboxylic ester hydrolase activity
C3496_RS11260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_RS11265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C3496_RS11270	COG5504	Zn-dependent protease
C3496_RS11280	COG0180	Tryptophanyl-tRNA synthetase
C3496_RS11290	COG4166	transmembrane transport
C3496_RS11295	COG0601	transmembrane transport
C3496_RS11300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C3496_RS11305	COG0444	Belongs to the ABC transporter superfamily
C3496_RS11310	COG4608	Belongs to the ABC transporter superfamily
C3496_RS11315	COG0534	Mate efflux family protein
C3496_RS11320	COG4166	transmembrane transport
C3496_RS11335	COG0861	Integral membrane protein TerC family
C3496_RS11340	COG4862	establishment of competence for transformation
C3496_RS11345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_RS11355	COG1164	Oligoendopeptidase f
C3496_RS11370	COG2346	COG2346, Truncated hemoglobins
C3496_RS11375	COG4116	CYTH
C3496_RS11385	COG2357	RelA SpoT domain protein
C3496_RS11395	COG0564	pseudouridine synthase activity
C3496_RS11410	COG0772	Belongs to the SEDS family
C3496_RS11415	COG1216	Glycosyl transferase, family 2
C3496_RS11415	COG0463	Glycosyl transferase, family 2
C3496_RS11435	COG0457	Tetratricopeptide repeat
C3496_RS11435	COG0463	Glycosyl transferase, family 2
C3496_RS11455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C3496_RS11470	COG1091	dTDP-4-dehydrorhamnose reductase activity
C3496_RS11515	COG2153	protein acetylation
C3496_RS11525	COG2382	esterase
C3496_RS11540	COG5492	domain, Protein
C3496_RS11545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_RS11555	COG0512	Glutamine amidotransferase of anthranilate synthase
C3496_RS11555	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C3496_RS11590	COG1620	l-lactate permease
C3496_RS11595	COG5634	Uncharacterized conserved protein (DUF2278)
C3496_RS11655	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_RS11665	COG1476	TRANSCRIPTIONal
C3496_RS11810	COG4974	Belongs to the 'phage' integrase family
C3496_RS11820	COG2226	methyltransferase
C3496_RS11830	COG1686	Belongs to the peptidase S11 family
C3496_RS11835	COG0681	Belongs to the peptidase S26 family
C3496_RS11855	COG1396	sequence-specific DNA binding
C3496_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS11880	COG1176	ABC-type spermidine putrescine transport system, permease component I
C3496_RS11885	COG1177	transmembrane transport
C3496_RS11890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C3496_RS11900	COG2409	Drug exporters of the RND superfamily
C3496_RS11910	COG0564	pseudouridine synthase activity
C3496_RS11920	COG2340	Cysteine-rich secretory protein family
C3496_RS11925	COG0247	lactate metabolic process
C3496_RS11930	COG0277	FAD linked oxidase domain protein
C3496_RS11935	COG3835	regulator
C3496_RS11945	COG0745	RESPONSE REGULATOR receiver
C3496_RS11950	COG5002	protein histidine kinase activity
C3496_RS11955	COG2186	Transcriptional regulator
C3496_RS11975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C3496_RS11985	COG2116	formate transmembrane transporter activity
C3496_RS11990	COG0861	Integral membrane protein TerC family
C3496_RS11995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3496_RS12005	COG2030	dehydratase
C3496_RS12025	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS12030	COG3243	poly(R)-hydroxyalkanoic acid synthase
C3496_RS12040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3496_RS12055	COG1840	ABC-type Fe3 transport system, periplasmic component
C3496_RS12060	COG3842	ATPase activity
C3496_RS12085	COG1349	DNA-binding transcription factor activity
C3496_RS12095	COG0235	Class ii aldolase
C3496_RS12105	COG2861	carbohydrate metabolic process
C3496_RS12115	COG3852	Histidine kinase
C3496_RS12120	COG1846	Transcriptional regulator
C3496_RS12130	COG2318	DinB family
C3496_RS12135	COG5002	protein histidine kinase activity
C3496_RS12145	COG0720	synthase
C3496_RS12160	COG4873	Protein conserved in bacteria
C3496_RS12190	COG1780	Probably involved in ribonucleotide reductase function
C3496_RS12205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C3496_RS12210	COG1725	Transcriptional regulator
C3496_RS12215	COG1131	(ABC) transporter
C3496_RS12225	COG1131	(ABC) transporter
C3496_RS12230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C3496_RS12235	COG1266	CAAX protease self-immunity
C3496_RS12245	COG1522	sequence-specific DNA binding
C3496_RS12255	COG1335	isochorismatase
C3496_RS12265	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_RS12270	COG2070	2-Nitropropane dioxygenase
C3496_RS12275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C3496_RS12285	COG1696	Membrane protein involved in D-alanine export
C3496_RS12310	COG0716	FMN binding
C3496_RS12325	COG3173	Aminoglycoside phosphotransferase
C3496_RS12350	COG1968	undecaprenyl-diphosphatase activity
C3496_RS12365	COG1846	Transcriptional regulator
C3496_RS12375	COG1301	dicarboxylic acid transport
C3496_RS12380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C3496_RS12385	COG4709	membrane
C3496_RS12390	COG3874	Sporulation protein YtfJ
C3496_RS12410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_RS12415	COG0028	Belongs to the TPP enzyme family
C3496_RS12420	COG0440	acetolactate synthase activity
C3496_RS12495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C3496_RS12510	COG1183	phosphatidylcholine synthase activity
C3496_RS12515	COG1368	sulfuric ester hydrolase activity
C3496_RS12525	COG0019	diaminopimelate decarboxylase activity
C3496_RS12545	COG0529	Catalyzes the synthesis of activated sulfate
C3496_RS12550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3496_RS12570	COG1648	precorrin-2 dehydrogenase activity
C3496_RS12575	COG0733	neurotransmitter:sodium symporter activity
C3496_RS12595	COG1757	Na H antiporter
C3496_RS12610	COG4758	membrane
C3496_RS12615	COG4585	Histidine kinase
C3496_RS12620	COG2197	response regulator
C3496_RS12630	COG1114	Component of the transport system for branched-chain amino acids
C3496_RS12640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C3496_RS12655	COG1994	Peptidase M50
C3496_RS12680	COG0730	response to heat
C3496_RS12685	COG0306	phosphate transporter
C3496_RS12690	COG1392	Phosphate transport regulator
C3496_RS12695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_RS12710	COG3852	Histidine kinase
C3496_RS12715	COG1801	Protein of unknown function DUF72
C3496_RS12725	COG0582	viral genome integration into host DNA
C3496_RS12730	COG5002	protein histidine kinase activity
C3496_RS12745	COG0392	lysyltransferase activity
C3496_RS12745	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C3496_RS12760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3496_RS12765	COG1686	Belongs to the peptidase S11 family
C3496_RS12770	COG2715	membrane protein required for spore maturation
C3496_RS12775	COG0700	Nucleoside recognition
C3496_RS12780	COG1187	pseudouridine synthase activity
C3496_RS12790	COG1333	cytochrome c biogenesis protein
C3496_RS12795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C3496_RS12800	COG0745	RESPONSE REGULATOR receiver
C3496_RS12805	COG5002	protein histidine kinase activity
C3496_RS12810	COG2096	Adenosyltransferase
C3496_RS12815	COG4942	peptidase
C3496_RS12825	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C3496_RS12830	COG1141	Ferredoxin
C3496_RS12840	COG0514	ATP-dependent DNA helicase (RecQ)
C3496_RS12845	COG1266	CAAX protease self-immunity
C3496_RS12855	COG1408	metallophosphoesterase
C3496_RS12865	COG4862	establishment of competence for transformation
C3496_RS12870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C3496_RS12890	COG0492	ferredoxin-NADP+ reductase activity
C3496_RS12965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3496_RS12980	COG0142	geranyltranstransferase activity
C3496_RS12990	COG0142	geranyltranstransferase activity
C3496_RS13015	COG0457	Tetratricopeptide repeat
C3496_RS13035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C3496_RS13045	COG4347	Protein of unknown function (DUF1405)
C3496_RS13060	COG2738	Putative neutral zinc metallopeptidase
C3496_RS13070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS13075	COG1694	Mazg nucleotide pyrophosphohydrolase
C3496_RS13090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3496_RS13095	COG0438	transferase activity, transferring glycosyl groups
C3496_RS13130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C3496_RS13130	COG1199	ATP-dependent helicase activity
C3496_RS13150	COG3935	DnaD domain protein
C3496_RS13155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C3496_RS13165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_RS13165	COG4499	WXG100 protein secretion system (Wss), protein YukC
C3496_RS13225	COG0116	Belongs to the methyltransferase superfamily
C3496_RS13235	COG1199	ATP-dependent helicase activity
C3496_RS13240	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C3496_RS13250	COG3173	Aminoglycoside phosphotransferase
C3496_RS13255	COG0024	Methionine aminopeptidase
C3496_RS13265	COG2233	PERMEase
C3496_RS13270	COG2311	Membrane
C3496_RS13275	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3496_RS13285	COG0456	acetyltransferase
C3496_RS13320	COG0754	glutathionylspermidine amidase activity
C3496_RS13335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C3496_RS13360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C3496_RS13375	COG1215	transferase activity, transferring glycosyl groups
C3496_RS13380	COG0438	transferase activity, transferring glycosyl groups
C3496_RS13415	COG0328	RNA-DNA hybrid ribonuclease activity
C3496_RS13450	COG3403	YqcI/YcgG family
C3496_RS13455	COG1280	lysine exporter protein (LysE YggA)
C3496_RS13470	COG3162	membrane
C3496_RS13475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_RS13480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3496_RS13490	COG0475	glutathione-regulated potassium exporter activity
C3496_RS13495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3496_RS13500	COG4978	Transcriptional regulator
C3496_RS13500	COG0789	Transcriptional regulator
C3496_RS13510	COG2323	membrane
C3496_RS13515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C3496_RS13570	COG1923	regulation of RNA biosynthetic process
C3496_RS13580	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C3496_RS13585	COG1360	Flagellar Motor Protein
C3496_RS13590	COG2201	protein-glutamate methylesterase activity
C3496_RS13595	COG0643	Histidine kinase
C3496_RS13595	COG2198	Histidine kinase
C3496_RS13600	COG1776	CheC inhibitor of MCP methylation
C3496_RS13600	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_RS13615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C3496_RS13635	COG1256	bacterial-type flagellum assembly
C3496_RS13640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3496_RS13660	COG1815	bacterial-type flagellum-dependent cell motility
C3496_RS13665	COG1558	bacterial-type flagellum-dependent cell motility
C3496_RS13675	COG1766	The M ring may be actively involved in energy transduction
C3496_RS13680	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_RS13690	COG1157	protein secretion by the type III secretion system
C3496_RS13725	COG0835	chemotaxis
C3496_RS13725	COG0784	Response regulator, receiver
C3496_RS13735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3496_RS13740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C3496_RS13745	COG0741	lytic transglycosylase activity
C3496_RS13755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_RS13760	COG1776	CheC inhibitor of MCP methylation
C3496_RS13760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C3496_RS13770	COG1338	Plays a role in the flagellum-specific transport system
C3496_RS13775	COG1987	bacterial-type flagellum assembly
C3496_RS13785	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3496_RS13790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C3496_RS13795	COG1419	protein localization to endoplasmic reticulum
C3496_RS13800	COG4786	Flagellar basal body rod
C3496_RS13805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3496_RS13830	COG1309	transcriptional regulator
C3496_RS13850	COG2329	Antibiotic biosynthesis monooxygenase
C3496_RS13875	COG0583	DNA-binding transcription factor activity
C3496_RS13880	COG3842	ATPase activity
C3496_RS13885	COG0725	ABC transporter, periplasmic molybdate-binding protein
C3496_RS13895	COG1234	tRNA 3'-trailer cleavage
C3496_RS13925	COG1686	Belongs to the peptidase S11 family
C3496_RS13935	COG0406	alpha-ribazole phosphatase activity
C3496_RS13955	COG1846	Transcriptional regulator
C3496_RS13965	COG0367	asparagine synthase
C3496_RS13995	COG1802	Transcriptional regulator
C3496_RS14000	COG0697	spore germination
C3496_RS14005	COG0523	cobalamin synthesis protein
C3496_RS14015	COG0438	transferase activity, transferring glycosyl groups
C3496_RS14015	COG1216	Glycosyl transferase, family 2
C3496_RS14020	COG1757	Na H antiporter
C3496_RS14025	COG0789	Transcriptional regulator
C3496_RS14035	COG0114	fumarate hydratase activity
C3496_RS14050	COG0534	Mate efflux family protein
C3496_RS14055	COG3340	Belongs to the peptidase S51 family
C3496_RS14075	COG0785	Cytochrome C biogenesis protein
C3496_RS14100	COG2733	membrane
C3496_RS14135	COG1131	(ABC) transporter
C3496_RS14150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_RS14155	COG0528	UMP kinase activity
C3496_RS14165	COG1027	Aspartate ammonia-lyase
C3496_RS14170	COG0281	malic enzyme
C3496_RS14175	COG4191	Histidine kinase
C3496_RS14180	COG0784	Response regulator, receiver
C3496_RS14185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3496_RS14205	COG3620	sequence-specific DNA binding
C3496_RS14240	COG2814	Major facilitator Superfamily
C3496_RS14255	COG1966	Carbon starvation protein
C3496_RS14265	COG0477	Major facilitator Superfamily
C3496_RS14270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_RS14275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3496_RS14280	COG4166	transmembrane transport
C3496_RS14285	COG2223	nitrite transmembrane transporter activity
C3496_RS14290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3496_RS14305	COG2244	polysaccharide biosynthetic process
C3496_RS14310	COG0733	neurotransmitter:sodium symporter activity
C3496_RS14320	COG5566	PFAM Mor transcription activator
C3496_RS14325	COG2323	membrane
C3496_RS14340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C3496_RS14350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_RS14355	COG0028	Belongs to the TPP enzyme family
C3496_RS14365	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C3496_RS14375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C3496_RS14400	COG2814	Major facilitator Superfamily
C3496_RS14405	COG3384	dioxygenase
C3496_RS14415	COG3279	Response regulator of the LytR AlgR family
C3496_RS14420	COG0427	acetyl-CoA hydrolase
C3496_RS14440	COG1073	alpha beta
C3496_RS14445	COG4166	transmembrane transport
C3496_RS14465	COG0535	radical SAM domain protein
C3496_RS14470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS14495	COG1914	H( )-stimulated, divalent metal cation uptake system
C3496_RS14510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3496_RS14515	COG0531	amino acid
C3496_RS14550	COG0714	Associated with various cellular activities
C3496_RS14560	COG3552	Protein containing von Willebrand factor type A (VWA) domain
C3496_RS14585	COG2390	Transcriptional regulator
C3496_RS14595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS14600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C3496_RS14610	COG4846	Membrane protein involved in cytochrome C biogenesis
C3496_RS14640	COG2132	Multicopper oxidase
C3496_RS14655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3496_RS14705	COG1114	Component of the transport system for branched-chain amino acids
C3496_RS14715	COG2372	response to copper ion
C3496_RS14715	COG1276	copper resistance
C3496_RS14720	COG4549	nuclear export factor GLE1
C3496_RS14730	COG0697	spore germination
C3496_RS14735	COG0583	DNA-binding transcription factor activity
C3496_RS14740	COG1959	2 iron, 2 sulfur cluster binding
C3496_RS14745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C3496_RS14750	COG0778	Nitroreductase
C3496_RS14760	COG0628	permease
C3496_RS14775	COG1231	oxidoreductase activity
C3496_RS14780	COG0523	cobalamin synthesis protein
C3496_RS14790	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_RS14795	COG2030	dehydratase
C3496_RS14800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_RS14810	COG0411	ABC transporter
C3496_RS14830	COG0583	DNA-binding transcription factor activity
C3496_RS14840	COG1942	4-Oxalocrotonate Tautomerase
C3496_RS14860	COG1271	oxidase subunit
C3496_RS14865	COG1294	oxidase, subunit
C3496_RS14870	COG4988	ABC transporter
C3496_RS14875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C3496_RS14890	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_RS14895	COG1686	Belongs to the peptidase S11 family
C3496_RS14905	COG1388	LysM domain
C3496_RS14905	COG0791	NLP P60 protein
C3496_RS14915	COG1132	(ABC) transporter
C3496_RS14920	COG0745	RESPONSE REGULATOR receiver
C3496_RS14925	COG5002	protein histidine kinase activity
C3496_RS14935	COG0300	oxidoreductase activity
C3496_RS14940	COG4122	O-methyltransferase activity
C3496_RS14970	COG0460	homoserine dehydrogenase
C3496_RS14995	COG1316	TRANSCRIPTIONal
C3496_RS15005	COG0745	RESPONSE REGULATOR receiver
C3496_RS15010	COG5002	protein histidine kinase activity
C3496_RS15025	COG1285	pathogenesis
C3496_RS15030	COG1247	-acetyltransferase
C3496_RS15050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3496_RS15060	COG1082	Xylose isomerase domain protein TIM barrel
C3496_RS15070	COG2814	Major facilitator Superfamily
C3496_RS15075	COG1279	arginine transmembrane transporter activity
C3496_RS15080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS15090	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3496_RS15125	COG0577	efflux transmembrane transporter activity
C3496_RS15130	COG2002	toxin-antitoxin pair type II binding
C3496_RS15135	COG1404	Belongs to the peptidase S8 family
C3496_RS15140	COG0640	Transcriptional regulator
C3496_RS15145	COG0667	Aldo Keto reductase
C3496_RS15150	COG2814	Major facilitator Superfamily
C3496_RS15175	COG0840	transmembrane signaling receptor activity
C3496_RS15190	COG3949	Membrane
C3496_RS15195	COG0783	Belongs to the Dps family
C3496_RS15210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3496_RS15220	COG1231	oxidoreductase activity
C3496_RS15230	COG4989	oxidoreductase activity
C3496_RS15240	COG0523	cobalamin synthesis protein
C3496_RS15245	COG0456	acetyltransferase
C3496_RS15250	COG3443	Belongs to the bacterial solute-binding protein 9 family
C3496_RS15250	COG0803	Belongs to the bacterial solute-binding protein 9 family
C3496_RS15260	COG0702	epimerase
C3496_RS15270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3496_RS15280	COG4166	transmembrane transport
C3496_RS15295	COG0406	alpha-ribazole phosphatase activity
C3496_RS15305	COG5337	Spore coat protein CotH
C3496_RS15310	COG1051	belongs to the nudix hydrolase family
C3496_RS15315	COG0586	Pfam SNARE associated Golgi protein
C3496_RS15320	COG2244	polysaccharide biosynthetic process
C3496_RS15330	COG0701	Predicted permease
C3496_RS15335	COG3689	TIGRFAM TIGR03943 family protein
C3496_RS15340	COG1607	acyl-coa hydrolase
C3496_RS15350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C3496_RS15365	COG0702	epimerase
C3496_RS15370	COG2839	Protein conserved in bacteria
C3496_RS15375	COG1253	flavin adenine dinucleotide binding
C3496_RS15390	COG1114	Component of the transport system for branched-chain amino acids
C3496_RS15395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C3496_RS15415	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_RS15425	COG1876	peptidase activity
C3496_RS15435	COG0154	amidase activity
C3496_RS15440	COG2211	Major facilitator Superfamily
C3496_RS15455	COG2368	4-hydroxyphenylacetate
C3496_RS15465	COG0196	riboflavin kinase activity
C3496_RS15480	COG0251	oxidation-reduction process
C3496_RS15490	COG3971	2-oxopent-4-enoate hydratase activity
C3496_RS15510	COG1942	4-Oxalocrotonate Tautomerase
C3496_RS15520	COG0561	phosphatase activity
C3496_RS15530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C3496_RS15550	COG1819	glycosyl
C3496_RS15555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS15560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS15590	COG0456	acetyltransferase
C3496_RS15670	COG0582	viral genome integration into host DNA
C3496_RS15770	COG3874	Sporulation protein YtfJ
C3496_RS15795	COG2226	methyltransferase
C3496_RS15815	COG1082	Xylose isomerase domain protein TIM barrel
C3496_RS15820	COG0346	lactoylglutathione lyase activity
C3496_RS15830	COG0604	alcohol dehydrogenase
C3496_RS15835	COG1595	DNA-templated transcription, initiation
C3496_RS15855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C3496_RS15855	COG0426	domain, Protein
C3496_RS15875	COG0386	Belongs to the glutathione peroxidase family
C3496_RS15880	COG1305	Transglutaminase-like
C3496_RS15885	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C3496_RS15890	COG0714	Associated with various cellular activities
C3496_RS15905	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C3496_RS15910	COG1140	nitrate reductase beta subunit
C3496_RS15915	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C3496_RS15920	COG2181	nitrate reductase activity
C3496_RS15925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C3496_RS15930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C3496_RS15935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_RS15940	COG0303	'Molybdopterin
C3496_RS15945	COG0314	molybdopterin synthase activity
C3496_RS15955	COG2223	nitrite transmembrane transporter activity
C3496_RS15970	COG1648	precorrin-2 dehydrogenase activity
C3496_RS15980	COG1587	Uroporphyrinogen-III synthase
C3496_RS15980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C3496_RS15985	COG2146	nitrite reductase [NAD(P)H] activity
C3496_RS15990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C3496_RS15995	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
C3496_RS16030	COG2359	stage V sporulation protein S
C3496_RS16070	COG1418	mRNA catabolic process
C3496_RS16075	COG0488	(ABC) transporter
C3496_RS16090	COG0629	single-stranded DNA binding
C3496_RS16095	COG1413	lyase activity
C3496_RS16110	COG2136	Putative SAM-dependent methyltransferase
C3496_RS16110	COG2521	methyltransferase
C3496_RS16155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C3496_RS16160	COG0017	Asparaginyl-tRNA synthetase
C3496_RS16180	COG1674	ftsk spoiiie
C3496_RS16295	COG0733	neurotransmitter:sodium symporter activity
C3496_RS16320	COG2610	gluconate transmembrane transporter activity
C3496_RS16325	COG1454	alcohol dehydrogenase
C3496_RS16330	COG1794	racemase activity, acting on amino acids and derivatives
C3496_RS16340	COG0456	acetyltransferase
C3496_RS16345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C3496_RS16355	COG1131	(ABC) transporter
C3496_RS16360	COG4473	ABC transporter
C3496_RS16370	COG0546	phosphoglycolate phosphatase activity
C3496_RS16390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_RS16405	COG0768	penicillin binding
C3496_RS16415	COG0204	Acyl-transferase
C3496_RS16420	COG1272	protein, Hemolysin III
C3496_RS16430	COG0805	protein transport
C3496_RS16440	COG1307	EDD domain protein, DegV family
C3496_RS16450	COG1999	signal sequence binding
C3496_RS16455	COG0071	Belongs to the small heat shock protein (HSP20) family
C3496_RS16460	COG0367	asparagine synthase
C3496_RS16480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS16485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C3496_RS16500	COG1335	isochorismatase
C3496_RS16505	COG1051	belongs to the nudix hydrolase family
C3496_RS16510	COG0071	Belongs to the small heat shock protein (HSP20) family
C3496_RS16515	COG0668	transmembrane transport
C3496_RS16520	COG4585	Histidine kinase
C3496_RS16520	COG2203	Gaf domain
C3496_RS16525	COG2197	response regulator
C3496_RS16530	COG1737	Transcriptional regulator
C3496_RS16535	COG1064	alcohol dehydrogenase
C3496_RS16590	COG0517	IMP dehydrogenase activity
C3496_RS16590	COG1125	glycine betaine transport
C3496_RS16595	COG1174	glycine betaine transport
C3496_RS16630	COG1253	flavin adenine dinucleotide binding
C3496_RS16635	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS16640	COG5506	Protein of unknown function (DUF1694)
C3496_RS16655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3496_RS16660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C3496_RS16665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C3496_RS16670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C3496_RS16675	COG0456	acetyltransferase
C3496_RS16680	COG3829	transcription factor binding
C3496_RS16685	COG1509	lysine 2,3-aminomutase activity
C3496_RS16720	COG3064	Membrane
C3496_RS16720	COG4991	sh3 domain protein
C3496_RS16720	COG0515	serine threonine protein kinase
C3496_RS16725	COG4326	sporulation control protein
C3496_RS16730	COG0671	phosphoesterase, PA-phosphatase related
C3496_RS16735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C3496_RS16740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_RS16810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C3496_RS16850	COG4499	WXG100 protein secretion system (Wss), protein YukC
C3496_RS16850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C3496_RS16860	COG2814	Major facilitator Superfamily
C3496_RS16865	COG4841	protein insertion into membrane
C3496_RS16870	COG0372	Belongs to the citrate synthase family
C3496_RS16875	COG2079	MmgE PrpD family protein
C3496_RS16880	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C3496_RS16885	COG1960	acyl-CoA dehydrogenase activity
C3496_RS16890	COG2084	Dehydrogenase
C3496_RS16900	COG1280	lysine exporter protein (LysE YggA)
C3496_RS16905	COG1024	Enoyl-CoA hydratase
C3496_RS16920	COG0420	3'-5' exonuclease activity
C3496_RS16945	COG2223	nitrite transmembrane transporter activity
C3496_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS16955	COG1169	isochorismate synthase
C3496_RS16960	COG1021	2,3-dihydroxybenzoate-AMP ligase
C3496_RS16965	COG1535	isochorismatase
C3496_RS16965	COG3433	isochorismatase activity
C3496_RS16970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C3496_RS16975	COG3251	PFAM MbtH domain protein
C3496_RS16980	COG2814	Major facilitator Superfamily
C3496_RS16995	COG0776	regulation of translation
C3496_RS17005	COG2318	DinB family
C3496_RS17015	COG1115	amino acid carrier protein
C3496_RS17030	COG2329	Antibiotic biosynthesis monooxygenase
C3496_RS17035	COG1187	pseudouridine synthase activity
C3496_RS17040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C3496_RS17045	COG1136	(ABC) transporter
C3496_RS17055	COG0596	Alpha beta hydrolase
C3496_RS17060	COG2814	Major facilitator Superfamily
C3496_RS17075	COG0028	Belongs to the TPP enzyme family
C3496_RS17155	COG1247	-acetyltransferase
C3496_RS17185	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C3496_RS17200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS17210	COG1278	Cold shock
C3496_RS17225	COG0010	Belongs to the arginase family
C3496_RS17230	COG0561	phosphatase activity
C3496_RS17240	COG0583	DNA-binding transcription factor activity
C3496_RS17245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3496_RS17260	COG0583	DNA-binding transcription factor activity
C3496_RS17265	COG2258	MOSC domain
C3496_RS17280	COG1132	(ABC) transporter
C3496_RS17285	COG1132	(ABC) transporter
C3496_RS17305	COG1396	sequence-specific DNA binding
C3496_RS17335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C3496_RS17345	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C3496_RS17350	COG1595	DNA-templated transcription, initiation
C3496_RS17375	COG1649	PFAM Uncharacterised BCR, COG1649
C3496_RS17400	COG2971	BadF BadG BcrA BcrD
C3496_RS17410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C3496_RS17445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS17475	COG1309	transcriptional regulator
C3496_RS17490	COG1136	(ABC) transporter
C3496_RS17490	COG0577	efflux transmembrane transporter activity
C3496_RS17495	COG3615	Tellurite resistance protein tehB
C3496_RS17495	COG0500	methyltransferase
C3496_RS17505	COG3961	Belongs to the TPP enzyme family
C3496_RS17510	COG1846	Transcriptional regulator
C3496_RS17535	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3496_RS17545	COG0110	maltose O-acetyltransferase activity
C3496_RS17555	COG0768	penicillin binding
C3496_RS17560	COG1595	DNA-templated transcription, initiation
C3496_RS17570	COG0768	penicillin binding
C3496_RS17575	COG0768	penicillin binding
C3496_RS17580	COG2367	Beta-lactamase
C3496_RS17590	COG1609	Transcriptional regulator
C3496_RS17595	COG2814	Major facilitator Superfamily
C3496_RS17600	COG0673	inositol 2-dehydrogenase activity
C3496_RS17625	COG0191	fructose-bisphosphate aldolase activity
C3496_RS17630	COG3718	enzyme involved in inositol metabolism
C3496_RS17645	COG3773	Cell wall hydrolase
C3496_RS17650	COG2755	lipolytic protein G-D-S-L family
C3496_RS17650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C3496_RS17665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS17710	COG1131	(ABC) transporter
C3496_RS17725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS17750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C3496_RS17800	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_RS17825	COG1131	(ABC) transporter
C3496_RS17835	COG1309	transcriptional regulator
C3496_RS17850	COG1960	acyl-CoA dehydrogenase activity
C3496_RS17855	COG0439	Biotin carboxylase
C3496_RS17860	COG0511	ligase activity, forming carbon-carbon bonds
C3496_RS17865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C3496_RS17870	COG1024	Enoyl-CoA hydratase
C3496_RS17875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C3496_RS17880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C3496_RS17890	COG1247	-acetyltransferase
C3496_RS17895	COG0572	uridine kinase
C3496_RS17905	COG2318	DinB family
C3496_RS17910	COG1686	Belongs to the peptidase S11 family
C3496_RS17935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C3496_RS17940	COG2910	NAD(P)H-binding
C3496_RS17955	COG3227	Zinc metalloprotease (Elastase)
C3496_RS17960	COG2207	Transcriptional regulator
C3496_RS18005	COG0789	Transcriptional regulator
C3496_RS18020	COG2226	methyltransferase
C3496_RS18035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C3496_RS18055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS18070	COG1063	alcohol dehydrogenase
C3496_RS18075	COG2323	membrane
C3496_RS18090	COG3386	PFAM SMP-30 Gluconolaconase
C3496_RS18100	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
C3496_RS18105	COG3773	Cell wall hydrolase
C3496_RS18115	COG0745	RESPONSE REGULATOR receiver
C3496_RS18120	COG2205	protein histidine kinase activity
C3496_RS18125	COG0488	(ABC) transporter
C3496_RS18140	COG1136	(ABC) transporter
C3496_RS18145	COG0577	efflux transmembrane transporter activity
C3496_RS18165	COG0460	homoserine dehydrogenase
C3496_RS18170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS18180	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C3496_RS18255	COG2124	cytochrome p450
C3496_RS18290	COG0561	phosphatase activity
C3496_RS18295	COG5002	protein histidine kinase activity
C3496_RS18300	COG0768	penicillin binding
C3496_RS18305	COG1819	glycosyl
C3496_RS18310	COG1794	racemase activity, acting on amino acids and derivatives
C3496_RS18335	COG2205	protein histidine kinase activity
C3496_RS18345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3496_RS18350	COG0604	alcohol dehydrogenase
C3496_RS18355	COG0671	phosphoesterase, PA-phosphatase related
C3496_RS18360	COG0768	penicillin binding
C3496_RS18420	COG0693	protein deglycase activity
C3496_RS18445	COG0789	Transcriptional regulator
C3496_RS18450	COG2814	Major facilitator Superfamily
C3496_RS18465	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_RS18485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS18490	COG0697	spore germination
C3496_RS18510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_RS18520	COG2223	nitrite transmembrane transporter activity
C3496_RS18535	COG2816	NAD+ diphosphatase activity
C3496_RS18540	COG0592	DNA-directed DNA polymerase activity
C3496_RS18545	COG1051	belongs to the nudix hydrolase family
C3496_RS18580	COG3878	Protein conserved in bacteria
C3496_RS18600	COG4667	esterase of the alpha-beta hydrolase superfamily
C3496_RS18625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C3496_RS18640	COG0322	excinuclease ABC activity
C3496_RS18680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_RS18705	COG1011	Hydrolase
C3496_RS18725	COG1523	belongs to the glycosyl hydrolase 13 family
C3496_RS18730	COG3227	Zinc metalloprotease (Elastase)
C3496_RS18750	COG0346	lactoylglutathione lyase activity
C3496_RS18755	COG0201	protein transport
C3496_RS18765	COG0697	spore germination
C3496_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS18810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS18825	COG2959	enzyme of heme biosynthesis
C3496_RS18860	COG1309	transcriptional regulator
C3496_RS18890	COG3284	Transcriptional regulator
C3496_RS18900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS18905	COG1349	DNA-binding transcription factor activity
C3496_RS18925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3496_RS18930	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_RS18935	COG0022	dehydrogenase e1 component
C3496_RS18940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3496_RS18950	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS18955	COG0456	acetyltransferase
C3496_RS18955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3496_RS18990	COG4176	ABC-type proline glycine betaine transport system permease component
C3496_RS18995	COG4175	Glycine betaine
C3496_RS18995	COG0517	IMP dehydrogenase activity
C3496_RS19020	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C3496_RS19025	COG2153	protein acetylation
C3496_RS19030	COG3397	chitin binding
C3496_RS19035	COG1819	glycosyl
C3496_RS19050	COG2205	protein histidine kinase activity
C3496_RS19055	COG2226	methyltransferase
C3496_RS19090	COG3973	AAA domain
C3496_RS19110	COG0514	ATP-dependent DNA helicase (RecQ)
C3496_RS19130	COG4637	Psort location Cytoplasmic, score
C3496_RS19155	COG3397	chitin binding
C3496_RS19170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C3496_RS19175	COG1115	amino acid carrier protein
C3496_RS19180	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS19185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C3496_RS19195	COG3938	Belongs to the proline racemase family
C3496_RS19200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C3496_RS19240	COG0586	Pfam SNARE associated Golgi protein
C3496_RS19255	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C3496_RS19265	COG4166	transmembrane transport
C3496_RS19275	COG4948	Mandelate Racemase Muconate Lactonizing
C3496_RS19320	COG2936	dipeptidyl-peptidase activity
C3496_RS19325	COG5002	protein histidine kinase activity
C3496_RS19330	COG0745	RESPONSE REGULATOR receiver
C3496_RS19360	COG1164	Oligoendopeptidase f
C3496_RS19365	COG0531	amino acid
C3496_RS19370	COG1522	sequence-specific DNA binding
C3496_RS19385	COG1307	EDD domain protein, DegV family
C3496_RS19410	COG2814	Major facilitator Superfamily
C3496_RS19415	COG1664	Polymer-forming cytoskeletal
C3496_RS19420	COG1664	Polymer-forming cytoskeletal
C3496_RS19425	COG0789	Transcriptional regulator
C3496_RS19430	COG4533	DNA binding
C3496_RS19435	COG2814	Major facilitator Superfamily
C3496_RS19435	COG0477	Major facilitator Superfamily
C3496_RS19455	COG2261	transglycosylase associated protein
C3496_RS19470	COG2226	methyltransferase
C3496_RS19505	COG0436	Aminotransferase
C3496_RS19510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C3496_RS19520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C3496_RS19535	COG1131	(ABC) transporter
C3496_RS19585	COG0628	permease
C3496_RS19595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3496_RS19600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C3496_RS19605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C3496_RS19640	COG2746	aminoglycoside 3-N-acetyltransferase activity
C3496_RS19660	COG0697	spore germination
C3496_RS19665	COG2318	DinB family
C3496_RS19685	COG4912	Dna alkylation repair
C3496_RS19705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_RS19710	COG0861	Integral membrane protein TerC family
C3496_RS19715	COG1368	sulfuric ester hydrolase activity
C3496_RS19720	COG0488	(ABC) transporter
C3496_RS19730	COG1033	growth of symbiont in host cell
C3496_RS19730	COG2409	Drug exporters of the RND superfamily
C3496_RS19735	COG1309	transcriptional regulator
C3496_RS19750	COG0287	Prephenate dehydrogenase
C3496_RS19765	COG1605	Chorismate mutase
C3496_RS19765	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C3496_RS19800	COG1388	LysM domain
C3496_RS19800	COG3584	3D domain protein
C3496_RS19810	COG2610	gluconate transmembrane transporter activity
C3496_RS19815	COG1024	Enoyl-CoA hydratase
C3496_RS19825	COG3290	protein histidine kinase activity
C3496_RS19825	COG3829	transcription factor binding
C3496_RS19840	COG1879	ABC-type sugar transport system periplasmic component
C3496_RS19850	COG1172	Belongs to the binding-protein-dependent transport system permease family
C3496_RS19860	COG2390	Transcriptional regulator
C3496_RS19865	COG1070	Carbohydrate kinase
C3496_RS19900	COG2329	Antibiotic biosynthesis monooxygenase
C3496_RS19920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C3496_RS19930	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C3496_RS19935	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_RS19950	COG4187	Peptidase family M20/M25/M40
C3496_RS19955	COG1414	Transcriptional regulator
C3496_RS19960	COG0833	amino acid
C3496_RS19965	COG1690	Belongs to the RtcB family
C3496_RS19970	COG3239	Fatty acid desaturase
C3496_RS19975	COG1785	Belongs to the alkaline phosphatase family
C3496_RS19985	COG3655	Transcriptional regulator
C3496_RS20000	COG4377	Putative membrane peptidase family (DUF2324)
C3496_RS20010	COG3279	Response regulator of the LytR AlgR family
C3496_RS20020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS20025	COG0346	lactoylglutathione lyase activity
C3496_RS20045	COG0714	Associated with various cellular activities
C3496_RS20070	COG0463	Glycosyl transferase, family 2
C3496_RS20085	COG0463	Glycosyl transferase, family 2
C3496_RS20095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3496_RS20100	COG0753	catalase activity
C3496_RS20110	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C3496_RS20120	COG1280	lysine exporter protein (LysE YggA)
C3496_RS20125	COG3403	YqcI/YcgG family
C3496_RS20160	COG0778	Nitroreductase
C3496_RS20165	COG1846	Transcriptional regulator
C3496_RS20185	COG4884	unkown
C3496_RS20185	COG3831	ATPase activity
C3496_RS20195	COG1136	(ABC) transporter
C3496_RS20225	COG0456	acetyltransferase
C3496_RS20245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS20285	COG0730	response to heat
C3496_RS20295	COG0833	amino acid
C3496_RS20305	COG4335	DNA alkylation repair
C3496_RS20310	COG0789	Transcriptional regulator
C3496_RS20310	COG4978	Transcriptional regulator
C3496_RS20340	COG0768	penicillin binding
C3496_RS20375	COG1984	allophanate hydrolase subunit 2
C3496_RS20380	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C3496_RS20385	COG1414	Transcriptional regulator
C3496_RS20400	COG0860	N-Acetylmuramoyl-L-alanine amidase
C3496_RS20405	COG0640	Transcriptional regulator
C3496_RS20420	COG1960	acyl-CoA dehydrogenase activity
C3496_RS20435	COG3314	Sporulation integral membrane protein YlbJ
C3496_RS20450	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C3496_RS20465	COG3848	Pyruvate phosphate dikinase
C3496_RS20465	COG0574	Belongs to the PEP-utilizing enzyme family
C3496_RS20475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS20480	COG5577	PFAM Coat F domain
C3496_RS20485	COG3403	YqcI/YcgG family
C3496_RS20490	COG1280	lysine exporter protein (LysE YggA)
C3496_RS20495	COG1113	amino acid transport
C3496_RS20525	COG1063	alcohol dehydrogenase
C3496_RS20535	COG1027	Aspartate ammonia-lyase
C3496_RS20540	COG0252	asparaginase activity
C3496_RS20545	COG1396	sequence-specific DNA binding
C3496_RS20550	COG2801	Transposase and inactivated derivatives
C3496_RS20555	COG0322	excinuclease ABC activity
C3496_RS20560	COG0531	amino acid
C3496_RS20565	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_RS20575	COG0784	Response regulator, receiver
C3496_RS20580	COG4191	Histidine kinase
C3496_RS20590	COG1115	amino acid carrier protein
C3496_RS20620	COG0737	Belongs to the 5'-nucleotidase family
C3496_RS20625	COG0753	catalase activity
C3496_RS20630	COG2267	carboxylic ester hydrolase activity
C3496_RS20635	COG1335	isochorismatase
C3496_RS20655	COG0583	DNA-binding transcription factor activity
C3496_RS20715	COG0415	Belongs to the DNA photolyase family
C3496_RS20720	COG0288	reversible hydration of carbon dioxide
C3496_RS20730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C3496_RS20735	COG5609	conserved protein (DUF2294)
C3496_RS20750	COG1575	Belongs to the MenA family. Type 1 subfamily
C3496_RS20755	COG2267	carboxylic ester hydrolase activity
C3496_RS20760	COG4641	Protein conserved in bacteria
C3496_RS20765	COG1136	(ABC) transporter
C3496_RS20770	COG0577	efflux transmembrane transporter activity
C3496_RS20820	COG0798	PFAM Bile acid sodium symporter
C3496_RS20825	COG0346	lactoylglutathione lyase activity
C3496_RS20830	COG0640	Transcriptional regulator
C3496_RS20845	COG0443	Heat shock 70 kDa protein
C3496_RS20860	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS20880	COG0346	lactoylglutathione lyase activity
C3496_RS20900	COG2169	Transcriptional regulator
C3496_RS20945	COG2814	Major facilitator Superfamily
C3496_RS21000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C3496_RS21025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS21030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C3496_RS21040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_RS21045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C3496_RS21065	COG0577	efflux transmembrane transporter activity
C3496_RS21080	COG5002	protein histidine kinase activity
C3496_RS21080	COG3850	Histidine kinase
C3496_RS21090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS21095	COG2271	Major facilitator Superfamily
C3496_RS21100	COG1556	Lactate utilization protein
C3496_RS21105	COG1139	Iron-sulfur cluster binding protein
C3496_RS21115	COG0583	DNA-binding transcription factor activity
C3496_RS21135	COG1619	proteins homologs of microcin C7 resistance protein MccF
C3496_RS21150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C3496_RS21170	COG0662	Cupin 2, conserved barrel domain protein
C3496_RS21175	COG2207	Transcriptional regulator
C3496_RS21175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS21205	COG3409	Peptidoglycan-binding domain 1 protein
C3496_RS21205	COG5632	N-Acetylmuramoyl-L-alanine amidase
C3496_RS21245	COG0477	Major facilitator Superfamily
C3496_RS21260	COG1846	Transcriptional regulator
C3496_RS21265	COG2814	Major facilitator Superfamily
C3496_RS21280	COG2076	Multidrug Resistance protein
C3496_RS21285	COG1309	transcriptional regulator
C3496_RS21295	COG2031	fatty acid transporter
C3496_RS21305	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_RS21340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C3496_RS21355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C3496_RS21360	COG1288	antiporter activity
C3496_RS21380	COG0789	Transcriptional regulator
C3496_RS21425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C3496_RS21440	COG1733	regulation of RNA biosynthetic process
C3496_RS21445	COG0778	Nitroreductase
C3496_RS21465	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS21475	COG1131	(ABC) transporter
C3496_RS21500	COG1011	Hydrolase
C3496_RS21510	COG2365	Tyrosine phosphatase family
C3496_RS21540	COG0346	lactoylglutathione lyase activity
C3496_RS21545	COG1940	carbohydrate kinase activity
C3496_RS21550	COG0738	Major facilitator superfamily
C3496_RS21555	COG0110	maltose O-acetyltransferase activity
C3496_RS21565	COG0577	efflux transmembrane transporter activity
C3496_RS21565	COG1136	(ABC) transporter
C3496_RS21585	COG0628	permease
C3496_RS21605	COG2226	methyltransferase
C3496_RS21645	COG1253	flavin adenine dinucleotide binding
C3496_RS21650	COG0789	Transcriptional regulator
C3496_RS21660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3496_RS21690	COG0697	spore germination
C3496_RS21695	COG1357	PFAM Pentapeptide repeats (8 copies)
C3496_RS21700	COG3813	Protein conserved in bacteria
C3496_RS21705	COG2706	6-phosphogluconolactonase activity
C3496_RS21710	COG1070	Carbohydrate kinase
C3496_RS21720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C3496_RS21725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C3496_RS21735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C3496_RS21740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C3496_RS21745	COG0604	alcohol dehydrogenase
C3496_RS21750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C3496_RS21760	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS21775	COG0840	transmembrane signaling receptor activity
C3496_RS21785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_RS21785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_RS21790	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3496_RS21790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C3496_RS21795	COG1733	regulation of RNA biosynthetic process
C3496_RS21820	COG0814	amino acid
C3496_RS21855	COG1393	Belongs to the ArsC family
C3496_RS21860	COG1733	regulation of RNA biosynthetic process
C3496_RS21865	COG2188	Transcriptional regulator
C3496_RS21870	COG0673	inositol 2-dehydrogenase activity
C3496_RS21875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C3496_RS21880	COG1733	regulation of RNA biosynthetic process
C3496_RS21885	COG1733	regulation of RNA biosynthetic process
C3496_RS21905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS21925	COG0384	phenazine biosynthesis protein PhzF
C3496_RS21935	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS21950	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_RS21955	COG2249	NAD(P)H dehydrogenase (quinone) activity
C3496_RS21960	COG1733	regulation of RNA biosynthetic process
C3496_RS21980	COG1191	sigma factor activity
C3496_RS21995	COG1309	transcriptional regulator
C3496_RS22015	COG3152	Membrane
C3496_RS22040	COG1151	hydroxylamine reductase activity
C3496_RS22050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS22055	COG3757	hydrolase, family 25
C3496_RS22055	COG3409	Peptidoglycan-binding domain 1 protein
C3496_RS22090	COG2072	flavoprotein involved in K transport
C3496_RS22135	COG0714	Associated with various cellular activities
C3496_RS22175	COG0604	alcohol dehydrogenase
C3496_RS22180	COG1113	amino acid transport
C3496_RS22185	COG2814	Major facilitator Superfamily
C3496_RS22215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3496_RS22220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C3496_RS22230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS22235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS22240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS22245	COG3739	integral membrane protein
C3496_RS22250	COG0384	phenazine biosynthesis protein PhzF
C3496_RS22285	COG0583	DNA-binding transcription factor activity
C3496_RS22295	COG2890	protein-(glutamine-N5) methyltransferase activity
C3496_RS22310	COG1193	negative regulation of DNA recombination
C3496_RS22325	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C3496_RS22330	COG1164	Oligoendopeptidase f
C3496_RS22335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C3496_RS22355	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_RS22380	COG0640	Transcriptional regulator
C3496_RS22385	COG0604	alcohol dehydrogenase
C3496_RS22395	COG0457	Tetratricopeptide repeat
C3496_RS22405	COG2808	Putative FMN-binding domain
C3496_RS22420	COG0385	Bile acid
C3496_RS22425	COG0277	FAD linked oxidase domain protein
C3496_RS22460	COG1216	Glycosyl transferase, family 2
C3496_RS22465	COG1024	Enoyl-CoA hydratase
C3496_RS22475	COG1285	pathogenesis
C3496_RS22490	COG2514	catechol 2,3-dioxygenase activity
C3496_RS22495	COG2720	vancomycin resistance protein
C3496_RS22530	COG0716	FMN binding
C3496_RS22560	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS22570	COG0165	Argininosuccinate lyase
C3496_RS22585	COG4145	pantothenate transmembrane transporter activity
C3496_RS22590	COG3924	membrane
C3496_RS22595	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS22600	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS22610	COG1657	PFAM Prenyltransferase squalene oxidase
C3496_RS22615	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C3496_RS22620	COG2962	Rard protein
C3496_RS22625	COG3326	Membrane
C3496_RS22640	COG0489	protein tyrosine kinase activity
C3496_RS22650	COG0314	molybdopterin synthase activity
C3496_RS22655	COG0303	'Molybdopterin
C3496_RS22660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C3496_RS22665	COG2116	formate transmembrane transporter activity
C3496_RS22675	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C3496_RS22680	COG5609	conserved protein (DUF2294)
C3496_RS22685	COG2427	Protein of unknown function (DUF1641)
C3496_RS22690	COG3383	formate dehydrogenase (NAD+) activity
C3496_RS22695	COG0697	spore germination
C3496_RS22740	COG2226	methyltransferase
C3496_RS22750	COG4166	transmembrane transport
C3496_RS22755	COG4166	transmembrane transport
C3496_RS22760	COG1301	dicarboxylic acid transport
C3496_RS22765	COG1316	TRANSCRIPTIONal
C3496_RS22775	COG1595	DNA-templated transcription, initiation
C3496_RS22785	COG1131	(ABC) transporter
C3496_RS22795	COG0673	inositol 2-dehydrogenase activity
C3496_RS22800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C3496_RS22805	COG0187	DNA topoisomerase II activity
C3496_RS22810	COG1832	CoA-binding protein
C3496_RS22815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C3496_RS22820	COG0745	RESPONSE REGULATOR receiver
C3496_RS22840	COG4841	protein insertion into membrane
C3496_RS22845	COG0824	Thioesterase
C3496_RS22875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C3496_RS22890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C3496_RS22920	COG2211	Major facilitator Superfamily
C3496_RS22930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C3496_RS22945	COG0183	Belongs to the thiolase family
C3496_RS22950	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_RS22955	COG1268	BioY protein
C3496_RS22960	COG0318	PFAM AMP-dependent synthetase and ligase
C3496_RS22975	COG1396	sequence-specific DNA binding
C3496_RS23025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS23035	COG5002	protein histidine kinase activity
C3496_RS23040	COG0400	carboxylic ester hydrolase activity
C3496_RS23045	COG0346	lactoylglutathione lyase activity
C3496_RS23050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C3496_RS23055	COG0069	glutamate synthase activity
C3496_RS23060	COG1902	pentaerythritol trinitrate reductase activity
C3496_RS23065	COG1329	Transcriptional regulator
C3496_RS23070	COG0010	Belongs to the arginase family
C3496_RS23130	COG4846	Membrane protein involved in cytochrome C biogenesis
C3496_RS23135	COG0785	Cytochrome C biogenesis protein
C3496_RS23145	COG1473	amidohydrolase
C3496_RS23155	COG1131	(ABC) transporter
C3496_RS23165	COG0583	DNA-binding transcription factor activity
C3496_RS23175	COG1346	cytolysis
C3496_RS23190	COG0730	response to heat
C3496_RS23215	COG1132	(ABC) transporter
C3496_RS23220	COG1132	(ABC) transporter
C3496_RS23260	COG0737	Belongs to the 5'-nucleotidase family
C3496_RS23270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C3496_RS23290	COG1695	Transcriptional regulator
C3496_RS23305	COG1196	nuclear chromosome segregation
C3496_RS23305	COG0741	lytic transglycosylase activity
C3496_RS23305	COG0739	heme binding
C3496_RS23310	COG0741	lytic transglycosylase activity
C3496_RS23340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C3496_RS23345	COG0174	glutamine synthetase
C3496_RS23350	COG0789	Transcriptional regulator
C3496_RS23355	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C3496_RS23360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C3496_RS23365	COG2860	membrane
C3496_RS23370	COG0464	growth
C3496_RS23400	COG1388	LysM domain
C3496_RS23400	COG3584	3D domain protein
C3496_RS23405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C3496_RS23405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3496_RS23405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C3496_RS23410	COG1105	Belongs to the carbohydrate kinase PfkB family
C3496_RS23415	COG1349	DNA-binding transcription factor activity
C3496_RS23420	COG1979	alcohol dehydrogenase
C3496_RS23425	COG2322	membrane
C3496_RS23435	COG1113	amino acid transport
C3496_RS23450	COG1408	metallophosphoesterase
C3496_RS23455	COG2116	formate transmembrane transporter activity
C3496_RS23470	COG2217	Heavy metal translocating P-type atpase
C3496_RS23475	COG2608	mercury ion transmembrane transporter activity
C3496_RS23480	COG1937	Protein conserved in bacteria
C3496_RS23490	COG2819	hydrolase of the alpha beta superfamily
C3496_RS23495	COG1120	ATPase activity
C3496_RS23500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS23505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C3496_RS23510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS23515	COG0708	Exodeoxyribonuclease III
C3496_RS23520	COG2169	Transcriptional regulator
C3496_RS23525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C3496_RS23530	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C3496_RS23540	COG2364	Membrane
C3496_RS23555	COG2267	carboxylic ester hydrolase activity
C3496_RS23560	COG0346	lactoylglutathione lyase activity
C3496_RS23565	COG3300	MHYT domain
C3496_RS23565	COG5001	Diguanylate cyclase
C3496_RS23585	COG1380	Effector of murein hydrolase LrgA
C3496_RS23590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C3496_RS23595	COG0596	Alpha beta hydrolase
C3496_RS23595	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_RS23600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C3496_RS23620	COG1404	Belongs to the peptidase S8 family
C3496_RS23625	COG3773	Cell wall hydrolase
C3496_RS23635	COG1368	sulfuric ester hydrolase activity
C3496_RS23640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C3496_RS23665	COG3321	synthase
C3496_RS23665	COG0604	alcohol dehydrogenase
C3496_RS23680	COG2086	electron transfer activity
C3496_RS23685	COG1960	acyl-CoA dehydrogenase activity
C3496_RS23700	COG1250	3-hydroxyacyl-CoA dehydrogenase
C3496_RS23725	COG1136	(ABC) transporter
C3496_RS23755	COG4550	Control of competence regulator ComK, YlbF/YmcA
C3496_RS23765	COG1013	pyruvate-flavodoxin oxidoreductase activity
C3496_RS23770	COG0674	pyruvate-flavodoxin oxidoreductase activity
C3496_RS23770	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C3496_RS23780	COG2359	stage V sporulation protein S
C3496_RS23785	COG1692	metallophosphoesterase
C3496_RS23810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C3496_RS23815	COG1426	Protein conserved in bacteria
C3496_RS23830	COG0300	oxidoreductase activity
C3496_RS23835	COG0612	Peptidase, M16
C3496_RS23840	COG0612	Peptidase, M16
C3496_RS23845	COG1079	Belongs to the binding-protein-dependent transport system permease family
C3496_RS23850	COG4603	Belongs to the binding-protein-dependent transport system permease family
C3496_RS23855	COG3845	ABC transporter
C3496_RS23860	COG1744	ABC transporter substrate-binding protein PnrA-like
C3496_RS23865	COG2188	Transcriptional regulator
C3496_RS23870	COG1674	ftsk spoiiie
C3496_RS23880	COG0740	serine-type endopeptidase activity
C3496_RS23885	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3496_RS23895	COG0527	aspartate kinase activity
C3496_RS23900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C3496_RS23905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3496_RS23930	COG4824	toxin secretion phage lysis holin
C3496_RS23980	COG0582	viral genome integration into host DNA
C3496_RS24010	COG0305	Participates in initiation and elongation during chromosome replication
C3496_RS24045	COG1396	sequence-specific DNA binding
C3496_RS24080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C3496_RS24085	COG1873	PFAM PRC-barrel domain
C3496_RS24090	COG0612	Peptidase, M16
C3496_RS24095	COG0726	polysaccharide deacetylase
C3496_RS24110	COG0196	riboflavin kinase activity
C3496_RS24125	COG1550	Protein conserved in bacteria
C3496_RS24135	COG1358	cellular component organization or biogenesis
C3496_RS24140	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C3496_RS24145	COG0195	Participates in both transcription termination and antitermination
C3496_RS24165	COG0750	zinc metalloprotease
C3496_RS24175	COG4589	Belongs to the CDS family
C3496_RS24190	COG0528	UMP kinase activity
C3496_RS24220	COG4974	Belongs to the 'phage' integrase family
C3496_RS24230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C3496_RS24235	COG0758	DNA mediated transformation
C3496_RS24240	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C3496_RS24280	COG1837	Belongs to the UPF0109 family
C3496_RS24290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C3496_RS24300	COG0552	protein localization to endoplasmic reticulum
C3496_RS24305	COG1196	nuclear chromosome segregation
C3496_RS24315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C3496_RS24320	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS24325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C3496_RS24340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C3496_RS24345	COG1461	Dihydroxyacetone kinase
C3496_RS24350	COG1302	Protein conserved in bacteria
C3496_RS24365	COG1564	THIamine pyrophosphokinase
C3496_RS24370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C3496_RS24380	COG2815	serine threonine protein kinase
C3496_RS24380	COG0515	serine threonine protein kinase
C3496_RS24385	COG0631	protein serine/threonine phosphatase activity
C3496_RS24395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C3496_RS24395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C3496_RS24405	COG0242	peptide deformylase activity
C3496_RS24410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C3496_RS24415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C3496_RS24435	COG1561	YicC-like family, N-terminal region
C3496_RS24440	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C3496_RS24450	COG0006	proline dipeptidase activity
C3496_RS24470	COG3069	C4-dicarboxylate transmembrane transporter activity
C3496_RS24535	COG0564	pseudouridine synthase activity
C3496_RS24555	COG3599	regulation of cell shape
C3496_RS24560	COG2302	S4 RNA-binding domain
C3496_RS24565	COG0762	integral membrane protein
C3496_RS24575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C3496_RS24580	COG1496	oxidoreductase activity
C3496_RS24585	COG1873	PFAM PRC-barrel domain
C3496_RS24590	COG1191	sigma factor activity
C3496_RS24595	COG1191	sigma factor activity
C3496_RS24605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C3496_RS24610	COG0849	cell division
C3496_RS24615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C3496_RS24630	COG0772	Belongs to the SEDS family
C3496_RS24645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C3496_RS24650	COG0768	penicillin binding
C3496_RS24655	COG0768	penicillin binding
C3496_RS24660	COG4839	cell division protein FtsL
C3496_RS24675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C3496_RS24690	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C3496_RS24695	COG1399	metal-binding, possibly nucleic acid-binding protein
C3496_RS24705	COG3480	Lon protease (S16) C-terminal proteolytic domain
C3496_RS24710	COG1752	Esterase of the alpha-beta hydrolase superfamily
C3496_RS24715	COG3314	Sporulation integral membrane protein YlbJ
C3496_RS24725	COG0742	ribosomal rna small subunit methyltransferase
C3496_RS24740	COG3679	Belongs to the UPF0342 family
C3496_RS24745	COG0406	alpha-ribazole phosphatase activity
C3496_RS24760	COG2340	Cysteine-rich secretory protein family
C3496_RS24775	COG3336	cytochrome c oxidase
C3496_RS24810	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C3496_RS24815	COG0772	Belongs to the SEDS family
C3496_RS24825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C3496_RS24830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C3496_RS24840	COG4896	Protein conserved in bacteria
C3496_RS24855	COG1217	gtp-binding protein TYPA
C3496_RS24865	COG0483	inositol monophosphate 1-phosphatase activity
C3496_RS24885	COG1982	Orn Lys Arg decarboxylase major
C3496_RS24935	COG0022	dehydrogenase e1 component
C3496_RS24940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3496_RS24950	COG0242	peptide deformylase activity
C3496_RS24955	COG0561	phosphatase activity
C3496_RS24965	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C3496_RS24970	COG0569	domain protein
C3496_RS24990	COG0583	DNA-binding transcription factor activity
C3496_RS24995	COG0517	IMP dehydrogenase activity
C3496_RS25005	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C3496_RS25015	COG4703	Protein of unknown function (DUF1797)
C3496_RS25030	COG2200	EAL domain
C3496_RS25035	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS25040	COG1408	metallophosphoesterase
C3496_RS25050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C3496_RS25085	COG2814	Major facilitator Superfamily
C3496_RS25105	COG3209	COG3209 Rhs family protein
C3496_RS25115	COG2205	protein histidine kinase activity
C3496_RS25125	COG0436	Aminotransferase
C3496_RS25130	COG1609	Transcriptional regulator
C3496_RS25135	COG3833	ABC-type maltose transport systems, permease component
C3496_RS25140	COG1175	transmembrane transport
C3496_RS25145	COG2182	Extracellular solute-binding protein
C3496_RS25155	COG0366	Alpha amylase catalytic
C3496_RS25160	COG3842	ATPase activity
C3496_RS25200	COG0183	Belongs to the thiolase family
C3496_RS25235	COG1695	Transcriptional regulator
C3496_RS25240	COG1028	Short-chain dehydrogenase reductase Sdr
C3496_RS25260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C3496_RS25265	COG0436	Aminotransferase
C3496_RS25300	COG2084	Dehydrogenase
C3496_RS25305	COG2199	diguanylate cyclase activity
C3496_RS25310	COG0778	Nitroreductase
C3496_RS25335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C3496_RS25335	COG1263	PTS System
C3496_RS25335	COG2190	(PTS) system
C3496_RS25340	COG3711	transcriptional antiterminator
C3496_RS25350	COG2188	Transcriptional regulator
C3496_RS25360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C3496_RS25385	COG1547	Domain of unknown function (DUF309)
C3496_RS25390	COG0456	acetyltransferase
C3496_RS25395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C3496_RS25400	COG4086	secreted protein
C3496_RS25405	COG0561	phosphatase activity
C3496_RS25410	COG0697	spore germination
C3496_RS25425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C3496_RS25450	COG0733	neurotransmitter:sodium symporter activity
C3496_RS25470	COG1686	Belongs to the peptidase S11 family
C3496_RS25475	COG1725	Transcriptional regulator
C3496_RS25480	COG1131	(ABC) transporter
C3496_RS25495	COG1846	Transcriptional regulator
C3496_RS25510	COG0598	Magnesium transport protein CorA
C3496_RS25535	COG4974	Belongs to the 'phage' integrase family
C3496_RS25545	COG0735	belongs to the Fur family
C3496_RS25550	COG1300	Membrane
C3496_RS25570	COG0667	Aldo Keto reductase
C3496_RS25575	COG0656	L-ascorbic acid biosynthetic process
C3496_RS25580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C3496_RS25580	COG0456	acetyltransferase
C3496_RS25590	COG0737	Belongs to the 5'-nucleotidase family
C3496_RS25590	COG1525	nuclease
C3496_RS25590	COG4085	toxin activity
C3496_RS25600	COG0596	Alpha beta hydrolase
C3496_RS25605	COG2056	Na+-H+ antiporter family
C3496_RS25610	COG1609	Transcriptional regulator
C3496_RS25615	COG0456	acetyltransferase
C3496_RS25620	COG1073	alpha beta
C3496_RS25635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_RS25635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C3496_RS25640	COG0307	riboflavin synthase, alpha
C3496_RS25665	COG4106	trans-aconitate 2-methyltransferase activity
C3496_RS25670	COG2226	methyltransferase
C3496_RS25670	COG1073	alpha beta
C3496_RS25685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C3496_RS25695	COG1757	Na H antiporter
C3496_RS25700	COG0737	Belongs to the 5'-nucleotidase family
C3496_RS25710	COG1522	sequence-specific DNA binding
C3496_RS25730	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C3496_RS25755	COG0300	oxidoreductase activity
C3496_RS25760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS25765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_RS25770	COG1760	l-serine dehydratase
C3496_RS25775	COG1760	l-serine dehydratase
C3496_RS25805	COG2195	Cleaves the N-terminal amino acid of tripeptides
C3496_RS25810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C3496_RS25825	COG1376	ErfK ybiS ycfS ynhG family protein
C3496_RS25830	COG4129	membrane
C3496_RS25835	COG1126	abc transporter atp-binding protein
C3496_RS25840	COG0765	amino acid transport
C3496_RS25845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C3496_RS25865	COG2323	membrane
C3496_RS25870	COG0772	Belongs to the SEDS family
C3496_RS25875	COG0508	dehydrogenase complex catalyzes the overall conversion of
C3496_RS25880	COG0022	dehydrogenase e1 component
C3496_RS25885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C3496_RS25890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C3496_RS25905	COG0280	phosphate acetyltransferase
C3496_RS25910	COG3829	transcription factor binding
C3496_RS25910	COG3290	protein histidine kinase activity
C3496_RS25920	COG0584	glycerophosphoryl diester phosphodiesterase
C3496_RS25925	COG3093	addiction module antidote protein HigA
C3496_RS25935	COG0745	RESPONSE REGULATOR receiver
C3496_RS25940	COG0750	zinc metalloprotease
C3496_RS25945	COG0497	DNA recombination
C3496_RS25955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C3496_RS25965	COG0142	geranyltranstransferase activity
C3496_RS25990	COG1302	Protein conserved in bacteria
C3496_RS25995	COG0439	Biotin carboxylase
C3496_RS26000	COG0511	ligase activity, forming carbon-carbon bonds
C3496_RS26045	COG3854	ATPases associated with a variety of cellular activities
C3496_RS26070	COG0006	proline dipeptidase activity
C3496_RS26085	COG3872	metal-dependent enzyme
C3496_RS26095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C3496_RS26130	COG0095	Lipoate-protein ligase
C3496_RS26135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C3496_RS26140	COG1609	Transcriptional regulator
C3496_RS26150	COG2076	Multidrug Resistance protein
C3496_RS26155	COG2076	Multidrug Resistance protein
C3496_RS26190	COG1131	(ABC) transporter
C3496_RS26195	COG1725	Transcriptional regulator
C3496_RS26225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C3496_RS26280	COG4970	Tfp pilus assembly protein FimT
C3496_RS26290	COG1459	type II secretion system
C3496_RS26295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C3496_RS26345	COG0646	methionine synthase
C3496_RS26345	COG1410	methionine synthase
C3496_RS26350	COG0646	methionine synthase
C3496_RS26350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C3496_RS26355	COG0626	cystathionine gamma-synthase activity
C3496_RS26360	COG0626	cystathionine gamma-synthase activity
C3496_RS26380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C3496_RS26390	COG1940	carbohydrate kinase activity
C3496_RS26395	COG4483	Protein conserved in bacteria
C3496_RS26400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C3496_RS26405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C3496_RS26410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C3496_RS26415	COG0704	Plays a role in the regulation of phosphate uptake
C3496_RS26425	COG0581	inorganic phosphate transmembrane transporter activity
C3496_RS26430	COG0573	inorganic phosphate transmembrane transporter activity
C3496_RS26435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C3496_RS26440	COG0768	penicillin binding
C3496_RS26445	COG0477	Major facilitator Superfamily
C3496_RS26450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C3496_RS26475	COG0735	belongs to the Fur family
C3496_RS26480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C3496_RS26485	COG1121	(ABC) transporter
C3496_RS26490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C3496_RS26520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C3496_RS26525	COG2384	SAM-dependent methyltransferase
C3496_RS26530	COG2010	Cytochrome c
C3496_RS26535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C3496_RS26540	COG0358	DNA primase activity
C3496_RS26550	COG0517	IMP dehydrogenase activity
C3496_RS26565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C3496_RS26570	COG0295	cytidine deaminase activity
C3496_RS26575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C3496_RS26585	COG1480	7TM receptor with intracellular HD hydrolase
C3496_RS26590	COG1702	phosphate starvation-inducible protein PhoH
C3496_RS26605	COG1610	YqeY-like protein
C3496_RS26610	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C3496_RS26615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C3496_RS26620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C3496_RS26650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C3496_RS26655	COG1733	regulation of RNA biosynthetic process
C3496_RS26680	COG1466	dna polymerase III delta subunit
C3496_RS26690	COG2333	competence protein COMEC
C3496_RS26690	COG0658	competence protein
C3496_RS26695	COG2131	deaminase
C3496_RS26700	COG1555	photosystem II stabilization
C3496_RS26700	COG1596	polysaccharide export
C3496_RS26705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C3496_RS26710	COG2226	methyltransferase
C3496_RS26715	COG0799	negative regulation of ribosome biogenesis
C3496_RS26720	COG1713	HD superfamily hydrolase involved in NAD metabolism
C3496_RS26730	COG1534	Rna-binding protein
C3496_RS26740	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C3496_RS26745	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C3496_RS26770	COG1595	DNA-templated transcription, initiation
C3496_RS26780	COG0778	Nitroreductase
C3496_RS26785	COG2357	RelA SpoT domain protein
C3496_RS26795	COG1785	Belongs to the alkaline phosphatase family
C3496_RS26805	COG2267	carboxylic ester hydrolase activity
C3496_RS26840	COG1404	Belongs to the peptidase S8 family
C3496_RS26845	COG3186	Phenylalanine-4-hydroxylase
C3496_RS26855	COG2514	catechol 2,3-dioxygenase activity
C3496_RS26860	COG2259	Doxx family
C3496_RS26900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C3496_RS26910	COG1454	alcohol dehydrogenase
C3496_RS26910	COG1012	belongs to the aldehyde dehydrogenase family
C3496_RS26915	COG0626	cystathionine gamma-synthase activity
C3496_RS26920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C3496_RS26945	COG0768	penicillin binding
C3496_RS26965	COG0826	peptidase U32
C3496_RS26970	COG0826	peptidase U32
C3496_RS26975	COG4122	O-methyltransferase activity
C3496_RS26980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C3496_RS27010	COG0628	permease
C3496_RS27030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C3496_RS27045	COG1104	cysteine desulfurase activity
C3496_RS27050	COG1959	2 iron, 2 sulfur cluster binding
C3496_RS27055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C3496_RS27065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C3496_RS27095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance