locus-tag	class	description
BD64_RS00015	COG5002	protein histidine kinase activity
BD64_RS00085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BD64_RS00120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_RS00175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BD64_RS00700	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BD64_RS00780	COG0356	it plays a direct role in the translocation of protons across the membrane
BD64_RS00825	COG3300	MHYT domain
BD64_RS00825	COG5001	Diguanylate cyclase
BD64_RS00875	COG0745	RESPONSE REGULATOR receiver
BD64_RS00880	COG5002	protein histidine kinase activity
BD64_RS00885	COG4863	YycH protein
BD64_RS00890	COG4853	Protein conserved in bacteria
BD64_RS00895	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BD64_RS00900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD64_RS00920	COG1164	Oligoendopeptidase f
BD64_RS00925	COG0516	GMP reductase activity
BD64_RS00945	COG1272	protein, Hemolysin III
BD64_RS00950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BD64_RS00970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BD64_RS00975	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BD64_RS00980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_RS00985	COG2814	Major facilitator Superfamily
BD64_RS00990	COG3275	phosphorelay sensor kinase activity
BD64_RS00995	COG3279	Response regulator of the LytR AlgR family
BD64_RS01010	COG0628	permease
BD64_RS01015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BD64_RS01015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BD64_RS01020	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BD64_RS01025	COG1309	transcriptional regulator
BD64_RS01030	COG0463	Glycosyl transferase, family 2
BD64_RS01055	COG0488	(ABC) transporter
BD64_RS01070	COG1607	acyl-coa hydrolase
BD64_RS01080	COG0840	transmembrane signaling receptor activity
BD64_RS01105	COG0477	Major facilitator Superfamily
BD64_RS01110	COG3279	Response regulator of the LytR AlgR family
BD64_RS01115	COG1966	Carbon starvation protein
BD64_RS01120	COG2879	small protein
BD64_RS01125	COG3706	GGDEF domain
BD64_RS01130	COG0351	phosphomethylpyrimidine kinase
BD64_RS01140	COG2197	response regulator
BD64_RS01150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BD64_RS01155	COG1011	Hydrolase
BD64_RS01165	COG2873	o-acetylhomoserine
BD64_RS01175	COG0460	homoserine dehydrogenase
BD64_RS01185	COG1609	Transcriptional regulator
BD64_RS01190	COG2755	lipolytic protein G-D-S-L family
BD64_RS01195	COG1131	(ABC) transporter
BD64_RS01200	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BD64_RS01210	COG2814	Major facilitator Superfamily
BD64_RS01215	COG0561	phosphatase activity
BD64_RS01220	COG2233	PERMEase
BD64_RS01225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BD64_RS01235	COG2363	Small membrane protein
BD64_RS01245	COG3773	Cell wall hydrolase
BD64_RS01260	COG0280	phosphate acetyltransferase
BD64_RS01265	COG0095	Lipoate-protein ligase
BD64_RS01285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS01290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS01295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS01300	COG1120	ATPase activity
BD64_RS01305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS01310	COG1078	dGTPase activity
BD64_RS01320	COG1994	Peptidase M50
BD64_RS01330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_RS01335	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_RS01340	COG0789	Transcriptional regulator
BD64_RS01345	COG2814	Major facilitator Superfamily
BD64_RS01355	COG0010	Belongs to the arginase family
BD64_RS01375	COG1619	proteins homologs of microcin C7 resistance protein MccF
BD64_RS01380	COG4506	Protein conserved in bacteria
BD64_RS01385	COG0018	arginyl-trna synthetase
BD64_RS01390	COG1595	DNA-templated transcription, initiation
BD64_RS01410	COG2234	aminopeptidase activity
BD64_RS01430	COG0024	Methionine aminopeptidase
BD64_RS01435	COG1131	(ABC) transporter
BD64_RS01440	COG0842	Transport permease protein
BD64_RS01445	COG4585	Histidine kinase
BD64_RS01450	COG2197	response regulator
BD64_RS01465	COG3300	MHYT domain
BD64_RS01465	COG5001	Diguanylate cyclase
BD64_RS01475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_RS01480	COG2181	nitrate reductase activity
BD64_RS01480	COG0247	lactate metabolic process
BD64_RS01485	COG0183	Belongs to the thiolase family
BD64_RS01490	COG1250	3-hydroxyacyl-CoA dehydrogenase
BD64_RS01495	COG1960	acyl-CoA dehydrogenase activity
BD64_RS01500	COG1960	acyl-CoA dehydrogenase activity
BD64_RS01510	COG3343	RNA polymerase activity
BD64_RS01520	COG4821	SIS domain
BD64_RS01540	COG1494	fructose-1,6-bisphosphatase
BD64_RS01545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BD64_RS01565	COG2890	protein-(glutamine-N5) methyltransferase activity
BD64_RS01580	COG0009	L-threonylcarbamoyladenylate synthase
BD64_RS01595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BD64_RS01600	COG2259	Doxx family
BD64_RS01605	COG2190	(PTS) system
BD64_RS01615	COG0698	ribose 5-phosphate isomerase
BD64_RS01650	COG0356	it plays a direct role in the translocation of protons across the membrane
BD64_RS01700	COG5001	Diguanylate cyclase
BD64_RS01700	COG3300	MHYT domain
BD64_RS01715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD64_RS01720	COG0649	NAD binding
BD64_RS01735	COG0839	Belongs to the complex I subunit 6 family
BD64_RS01745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD64_RS01750	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD64_RS01755	COG1007	ATP synthesis coupled electron transport
BD64_RS01760	COG4836	Membrane
BD64_RS01775	COG2385	sporulation resulting in formation of a cellular spore
BD64_RS01780	COG4555	ABC transporter
BD64_RS01785	COG3279	Response regulator of the LytR AlgR family
BD64_RS01800	COG0739	heme binding
BD64_RS01815	COG1609	Transcriptional regulator
BD64_RS01860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BD64_RS01865	COG1682	transport, permease protein
BD64_RS01870	COG1134	teichoic acid transport
BD64_RS01875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BD64_RS01890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BD64_RS01895	COG0745	RESPONSE REGULATOR receiver
BD64_RS01900	COG5002	protein histidine kinase activity
BD64_RS01935	COG1136	(ABC) transporter
BD64_RS01940	COG0577	efflux transmembrane transporter activity
BD64_RS01980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BD64_RS01985	COG4715	Zinc finger, swim domain protein
BD64_RS02010	COG3584	3D domain protein
BD64_RS02010	COG1388	LysM domain
BD64_RS02015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_RS02025	COG1215	transferase activity, transferring glycosyl groups
BD64_RS02035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS02050	COG1368	sulfuric ester hydrolase activity
BD64_RS02060	COG2389	metal-binding protein
BD64_RS02080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD64_RS02085	COG1294	oxidase, subunit
BD64_RS02090	COG1271	oxidase subunit
BD64_RS02105	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BD64_RS02110	COG0583	DNA-binding transcription factor activity
BD64_RS02115	COG1511	domain protein
BD64_RS02120	COG0346	lactoylglutathione lyase activity
BD64_RS02130	COG1301	dicarboxylic acid transport
BD64_RS02135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BD64_RS02145	COG1447	Phosphotransferase system cellobiose-specific component IIA
BD64_RS02150	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BD64_RS02155	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BD64_RS02165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BD64_RS02170	COG1447	Phosphotransferase system cellobiose-specific component IIA
BD64_RS02175	COG1486	melibiose metabolic process
BD64_RS02180	COG3394	polysaccharide catabolic process
BD64_RS02195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BD64_RS02195	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BD64_RS02205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BD64_RS02210	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BD64_RS02215	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BD64_RS02220	COG1316	TRANSCRIPTIONal
BD64_RS02225	COG1739	Uncharacterized protein family UPF0029
BD64_RS02230	COG1307	EDD domain protein, DegV family
BD64_RS02240	COG1733	regulation of RNA biosynthetic process
BD64_RS02245	COG1388	LysM domain
BD64_RS02245	COG0791	NLP P60 protein
BD64_RS02250	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BD64_RS02255	COG1040	competence protein
BD64_RS02260	COG1278	Cold shock
BD64_RS02265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BD64_RS02270	COG0653	protein targeting
BD64_RS02275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BD64_RS02290	COG2884	Cell division ATP-binding protein ftsE
BD64_RS02295	COG2177	Part of the ABC transporter FtsEX involved in
BD64_RS02300	COG3409	Peptidoglycan-binding domain 1 protein
BD64_RS02300	COG0793	Belongs to the peptidase S41A family
BD64_RS02305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD64_RS02310	COG1132	(ABC) transporter
BD64_RS02320	COG0488	(ABC) transporter
BD64_RS02325	COG0655	NAD(P)H dehydrogenase (quinone) activity
BD64_RS02335	COG0583	DNA-binding transcription factor activity
BD64_RS02340	COG2855	membrane
BD64_RS02365	COG0789	Transcriptional regulator
BD64_RS02385	COG0556	nucleotide-excision repair
BD64_RS02390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BD64_RS02400	COG1950	PFAM Membrane protein of
BD64_RS02420	COG0110	maltose O-acetyltransferase activity
BD64_RS02425	COG0457	Tetratricopeptide repeat
BD64_RS02430	COG0492	ferredoxin-NADP+ reductase activity
BD64_RS02440	COG1051	belongs to the nudix hydrolase family
BD64_RS02450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BD64_RS02460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BD64_RS02465	COG0740	serine-type endopeptidase activity
BD64_RS02470	COG2323	membrane
BD64_RS02485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_RS02510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BD64_RS02525	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BD64_RS02535	COG0149	triose-phosphate isomerase activity
BD64_RS02540	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BD64_RS02550	COG4974	Belongs to the 'phage' integrase family
BD64_RS02575	COG4695	Portal protein
BD64_RS02675	COG1346	cytolysis
BD64_RS02680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BD64_RS02685	COG1647	Serine aminopeptidase, S33
BD64_RS02690	COG0557	exoribonuclease II activity
BD64_RS02740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS02755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BD64_RS02760	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BD64_RS02770	COG3290	protein histidine kinase activity
BD64_RS02770	COG0840	transmembrane signaling receptor activity
BD64_RS02780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BD64_RS02785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BD64_RS02790	COG1252	NADH dehydrogenase
BD64_RS02800	COG1733	regulation of RNA biosynthetic process
BD64_RS02805	COG2814	Major facilitator Superfamily
BD64_RS02810	COG0656	L-ascorbic acid biosynthetic process
BD64_RS02825	COG2910	NAD(P)H-binding
BD64_RS02830	COG1115	amino acid carrier protein
BD64_RS02835	COG1115	amino acid carrier protein
BD64_RS02840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS02845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS02855	COG2311	Membrane
BD64_RS02870	COG1611	Belongs to the LOG family
BD64_RS02885	COG0783	Belongs to the Dps family
BD64_RS02890	COG1115	amino acid carrier protein
BD64_RS02900	COG0490	domain, Protein
BD64_RS02905	COG0475	glutathione-regulated potassium exporter activity
BD64_RS02920	COG1741	Belongs to the pirin family
BD64_RS02925	COG3227	Zinc metalloprotease (Elastase)
BD64_RS02930	COG2151	metal-sulfur cluster biosynthetic enzyme
BD64_RS02960	COG0745	RESPONSE REGULATOR receiver
BD64_RS02965	COG1376	ErfK ybiS ycfS ynhG family protein
BD64_RS02975	COG0586	Pfam SNARE associated Golgi protein
BD64_RS03010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS03020	COG0706	membrane insertase activity
BD64_RS03030	COG0531	amino acid
BD64_RS03035	COG2814	Major facilitator Superfamily
BD64_RS03055	COG0840	transmembrane signaling receptor activity
BD64_RS03060	COG0011	TIGRFAM Protein of
BD64_RS03075	COG1686	Belongs to the peptidase S11 family
BD64_RS03085	COG1024	Enoyl-CoA hydratase
BD64_RS03085	COG1250	3-hydroxyacyl-CoA dehydrogenase
BD64_RS03090	COG0183	Belongs to the thiolase family
BD64_RS03100	COG1960	acyl-CoA dehydrogenase activity
BD64_RS03105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS03110	COG1309	transcriptional regulator
BD64_RS03135	COG0039	L-malate dehydrogenase activity
BD64_RS03185	COG1393	Belongs to the ArsC family
BD64_RS03195	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BD64_RS03200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_RS03215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD64_RS03220	COG2011	ABC-type metal ion transport system permease component
BD64_RS03225	COG1464	Belongs to the NlpA lipoprotein family
BD64_RS03230	COG1464	Belongs to the NlpA lipoprotein family
BD64_RS03235	COG0396	ATPase activity
BD64_RS03240	COG0719	Fe-S assembly protein
BD64_RS03245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BD64_RS03250	COG0822	iron-sulfur transferase activity
BD64_RS03255	COG0719	Fe-S assembly protein
BD64_RS03270	COG1695	Transcriptional regulator
BD64_RS03280	COG0737	Belongs to the 5'-nucleotidase family
BD64_RS03285	COG3377	Domain of unknown function (DUF1805)
BD64_RS03295	COG0739	heme binding
BD64_RS03320	COG4377	Putative membrane peptidase family (DUF2324)
BD64_RS03325	COG0789	Transcriptional regulator
BD64_RS03335	COG4470	Protein conserved in bacteria
BD64_RS03355	COG1494	fructose-1,6-bisphosphatase
BD64_RS03360	COG2445	Protein of unknown function DUF86
BD64_RS03370	COG0647	UMP catabolic process
BD64_RS03375	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_RS03390	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BD64_RS03395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BD64_RS03405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BD64_RS03410	COG4837	Protein of unknown function (DUF1462)
BD64_RS03450	COG2824	Alkylphosphonate utilization operon protein PhnA
BD64_RS03455	COG0390	transport system, permease component
BD64_RS03470	COG1252	NADH dehydrogenase
BD64_RS03485	COG0316	Belongs to the HesB IscA family
BD64_RS03505	COG1683	Conserved Protein
BD64_RS03520	COG3708	Transcriptional regulator
BD64_RS03535	COG1252	NADH dehydrogenase
BD64_RS03550	COG3584	3D domain protein
BD64_RS03565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BD64_RS03570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BD64_RS03580	COG1268	BioY protein
BD64_RS03590	COG2050	protein possibly involved in aromatic compounds catabolism
BD64_RS03610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD64_RS03615	COG5018	Exonuclease
BD64_RS03635	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BD64_RS03645	COG2267	carboxylic ester hydrolase activity
BD64_RS03650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD64_RS03655	COG1522	sequence-specific DNA binding
BD64_RS03660	COG0436	Aminotransferase
BD64_RS03665	COG1098	S1 RNA binding domain
BD64_RS03670	COG2155	Conserved Protein
BD64_RS03680	COG0166	Belongs to the GPI family
BD64_RS03690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BD64_RS03695	COG1285	pathogenesis
BD64_RS03730	COG0544	peptidyl-prolyl cis-trans isomerase activity
BD64_RS03840	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BD64_RS03845	COG0297	glycogen (starch) synthase activity
BD64_RS03850	COG0058	SHG alpha-glucan phosphorylase activity
BD64_RS03875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BD64_RS03880	COG1575	Belongs to the MenA family. Type 1 subfamily
BD64_RS03885	COG1169	isochorismate synthase
BD64_RS03890	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BD64_RS03895	COG0596	Alpha beta hydrolase
BD64_RS03900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BD64_RS03910	COG4948	Mandelate Racemase Muconate Lactonizing
BD64_RS03940	COG3964	amidohydrolase
BD64_RS03960	COG2188	Transcriptional regulator
BD64_RS03980	COG1136	(ABC) transporter
BD64_RS03985	COG0577	efflux transmembrane transporter activity
BD64_RS03990	COG0577	efflux transmembrane transporter activity
BD64_RS04000	COG0577	efflux transmembrane transporter activity
BD64_RS04005	COG2205	protein histidine kinase activity
BD64_RS04010	COG0745	RESPONSE REGULATOR receiver
BD64_RS04015	COG2207	Transcriptional regulator
BD64_RS04015	COG3708	Transcriptional regulator
BD64_RS04020	COG1136	(ABC) transporter
BD64_RS04025	COG0577	efflux transmembrane transporter activity
BD64_RS04035	COG0586	Pfam SNARE associated Golgi protein
BD64_RS04070	COG1597	lipid kinase activity
BD64_RS04100	COG0745	RESPONSE REGULATOR receiver
BD64_RS04105	COG5002	protein histidine kinase activity
BD64_RS04140	COG1842	Phage shock protein A
BD64_RS04165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS04185	COG1294	oxidase, subunit
BD64_RS04190	COG1271	oxidase subunit
BD64_RS04195	COG0288	reversible hydration of carbon dioxide
BD64_RS04225	COG0494	nUDIX hydrolase
BD64_RS04250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_RS04255	COG1116	anion transmembrane transporter activity
BD64_RS04260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BD64_RS04280	COG2267	carboxylic ester hydrolase activity
BD64_RS04285	COG4191	Histidine kinase
BD64_RS04290	COG5002	protein histidine kinase activity
BD64_RS04295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BD64_RS04350	COG0521	Mo-molybdopterin cofactor biosynthetic process
BD64_RS04360	COG0438	transferase activity, transferring glycosyl groups
BD64_RS04365	COG0671	phosphoesterase, PA-phosphatase related
BD64_RS04370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BD64_RS04375	COG2267	carboxylic ester hydrolase activity
BD64_RS04395	COG1794	racemase activity, acting on amino acids and derivatives
BD64_RS04405	COG1131	(ABC) transporter
BD64_RS04410	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BD64_RS04415	COG1242	4 iron, 4 sulfur cluster binding
BD64_RS04435	COG1136	(ABC) transporter
BD64_RS04445	COG0582	viral genome integration into host DNA
BD64_RS04450	COG0490	domain, Protein
BD64_RS04455	COG0475	glutathione-regulated potassium exporter activity
BD64_RS04460	COG2814	Major facilitator Superfamily
BD64_RS04505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BD64_RS04515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_RS04540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_RS04550	COG0303	'Molybdopterin
BD64_RS04555	COG1763	Mo-molybdopterin cofactor biosynthetic process
BD64_RS04560	COG0314	molybdopterin synthase activity
BD64_RS04575	COG4975	Glucose uptake
BD64_RS04585	COG1329	Transcriptional regulator
BD64_RS04605	COG3832	glyoxalase III activity
BD64_RS04615	COG2814	Major facilitator Superfamily
BD64_RS04620	COG2081	HI0933 family
BD64_RS04625	COG2244	polysaccharide biosynthetic process
BD64_RS04630	COG1187	pseudouridine synthase activity
BD64_RS04635	COG1349	DNA-binding transcription factor activity
BD64_RS04640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_RS04645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_RS04660	COG1523	belongs to the glycosyl hydrolase 13 family
BD64_RS04665	COG0510	thiamine kinase activity
BD64_RS04680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS04690	COG1363	Peptidase, m42
BD64_RS04695	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BD64_RS04700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_RS04705	COG4848	Belongs to the UPF0354 family
BD64_RS04710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_RS04720	COG1674	ftsk spoiiie
BD64_RS04735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS04755	COG2309	aminopeptidase activity
BD64_RS04765	COG3118	belongs to the thioredoxin family
BD64_RS04770	COG4851	CamS sex pheromone cAM373 precursor
BD64_RS04780	COG1609	Transcriptional regulator
BD64_RS04815	COG0666	response to abiotic stimulus
BD64_RS04825	COG0745	RESPONSE REGULATOR receiver
BD64_RS04835	COG0123	including yeast histone deacetylase and acetoin utilization protein
BD64_RS04840	COG0517	IMP dehydrogenase activity
BD64_RS04845	COG0454	-acetyltransferase
BD64_RS04850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD64_RS04860	COG1595	DNA-templated transcription, initiation
BD64_RS04890	COG0626	cystathionine gamma-synthase activity
BD64_RS04895	COG1956	GAF domain-containing protein
BD64_RS04905	COG0697	spore germination
BD64_RS04910	COG0583	DNA-binding transcription factor activity
BD64_RS04920	COG1104	cysteine desulfurase activity
BD64_RS04935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD64_RS04945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BD64_RS04960	COG3874	Sporulation protein YtfJ
BD64_RS04965	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BD64_RS04970	COG0827	DNA restriction-modification system
BD64_RS04975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BD64_RS04995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS05035	COG0589	response to stress
BD64_RS05040	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS05055	COG1476	TRANSCRIPTIONal
BD64_RS05065	COG0662	Cupin 2, conserved barrel domain protein
BD64_RS05070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS05105	COG0006	proline dipeptidase activity
BD64_RS05120	COG4109	DRTGG domain
BD64_RS05140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BD64_RS05155	COG0587	DNA-directed DNA polymerase activity
BD64_RS05160	COG0281	malic enzyme
BD64_RS05165	COG1725	Transcriptional regulator
BD64_RS05190	COG3030	protein affecting phage T7 exclusion by the F plasmid
BD64_RS05195	COG0628	permease
BD64_RS05210	COG0372	Belongs to the citrate synthase family
BD64_RS05215	COG0538	isocitrate dehydrogenase activity
BD64_RS05235	COG0745	RESPONSE REGULATOR receiver
BD64_RS05240	COG5002	protein histidine kinase activity
BD64_RS05245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BD64_RS05245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BD64_RS05255	COG1971	Probably functions as a manganese efflux pump
BD64_RS05260	COG0237	dephospho-CoA kinase activity
BD64_RS05265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BD64_RS05270	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BD64_RS05280	COG3611	Membrane attachment protein
BD64_RS05285	COG1484	DNA-dependent DNA replication
BD64_RS05295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD64_RS05320	COG1363	Peptidase, m42
BD64_RS05325	COG1309	transcriptional regulator
BD64_RS05330	COG1566	PFAM secretion protein HlyD family protein
BD64_RS05335	COG2814	Major facilitator Superfamily
BD64_RS05360	COG1418	mRNA catabolic process
BD64_RS05370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BD64_RS05415	COG1286	toxin biosynthetic process
BD64_RS05420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BD64_RS05420	COG1796	DNA polymerase
BD64_RS05435	COG1187	pseudouridine synthase activity
BD64_RS05440	COG1114	Component of the transport system for branched-chain amino acids
BD64_RS05445	COG5386	Cell surface protein
BD64_RS05455	COG5386	Cell surface protein
BD64_RS05470	COG1120	ATPase activity
BD64_RS05475	COG4509	Sortase family
BD64_RS05490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BD64_RS05495	COG4895	conserved protein (DUF2196)
BD64_RS05505	COG0745	RESPONSE REGULATOR receiver
BD64_RS05510	COG2205	protein histidine kinase activity
BD64_RS05515	COG1131	(ABC) transporter
BD64_RS05545	COG2318	DinB family
BD64_RS05565	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_RS05570	COG1309	transcriptional regulator
BD64_RS05575	COG1024	Enoyl-CoA hydratase
BD64_RS05580	COG2086	electron transfer activity
BD64_RS05585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BD64_RS05590	COG3118	belongs to the thioredoxin family
BD64_RS05600	COG1719	4-vinyl reductase, 4VR
BD64_RS05605	COG2009	succinate dehydrogenase
BD64_RS05610	COG1053	succinate dehydrogenase
BD64_RS05615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BD64_RS05620	COG0824	Thioesterase
BD64_RS05625	COG1876	peptidase activity
BD64_RS05630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BD64_RS05640	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BD64_RS05645	COG4152	abc transporter atp-binding protein
BD64_RS05650	COG1668	transmembrane transport
BD64_RS05655	COG1959	2 iron, 2 sulfur cluster binding
BD64_RS05665	COG0697	spore germination
BD64_RS05670	COG1396	sequence-specific DNA binding
BD64_RS05675	COG1983	PspC domain protein
BD64_RS05690	COG3279	Response regulator of the LytR AlgR family
BD64_RS05695	COG3275	phosphorelay sensor kinase activity
BD64_RS05700	COG4608	Belongs to the ABC transporter superfamily
BD64_RS05705	COG0444	Belongs to the ABC transporter superfamily
BD64_RS05715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_RS05725	COG0402	S-adenosylhomocysteine deaminase activity
BD64_RS05730	COG0402	S-adenosylhomocysteine deaminase activity
BD64_RS05740	COG2233	PERMEase
BD64_RS05745	COG2197	response regulator
BD64_RS05760	COG1309	transcriptional regulator
BD64_RS05780	COG5401	PFAM Sporulation and spore germination
BD64_RS05795	COG0622	Phosphoesterase
BD64_RS05845	COG0470	DNA polymerase III
BD64_RS05845	COG1067	ATP-dependent peptidase activity
BD64_RS05860	COG1764	response to oxidative stress
BD64_RS05865	COG1846	Transcriptional regulator
BD64_RS05875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BD64_RS05885	COG1587	Uroporphyrinogen-III synthase
BD64_RS05890	COG0113	porphobilinogen synthase activity
BD64_RS05900	COG1388	LysM domain
BD64_RS05910	COG0525	valine-tRNA ligase activity
BD64_RS05915	COG0285	dihydrofolate synthase activity
BD64_RS05935	COG1077	Cell shape determining protein MreB Mrl
BD64_RS05955	COG2894	cell division
BD64_RS05960	COG0739	heme binding
BD64_RS05965	COG1994	Peptidase M50
BD64_RS05970	COG1530	ribonuclease E activity
BD64_RS05980	COG2868	ribosomal protein
BD64_RS05990	COG3290	protein histidine kinase activity
BD64_RS05995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD64_RS06000	COG0745	RESPONSE REGULATOR receiver
BD64_RS06010	COG5002	protein histidine kinase activity
BD64_RS06015	COG1136	(ABC) transporter
BD64_RS06020	COG0577	efflux transmembrane transporter activity
BD64_RS06025	COG0577	efflux transmembrane transporter activity
BD64_RS06030	COG0077	Prephenate dehydratase
BD64_RS06035	COG2258	MOSC domain
BD64_RS06040	COG1827	regulation of RNA biosynthetic process
BD64_RS06045	COG1104	cysteine desulfurase activity
BD64_RS06050	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BD64_RS06055	COG0157	Belongs to the NadC ModD family
BD64_RS06080	COG0640	Transcriptional regulator
BD64_RS06085	COG0697	spore germination
BD64_RS06090	COG0697	spore germination
BD64_RS06100	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BD64_RS06130	COG1862	Preprotein translocase
BD64_RS06140	COG2323	membrane
BD64_RS06145	COG2244	polysaccharide biosynthetic process
BD64_RS06155	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BD64_RS06155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BD64_RS06160	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BD64_RS06165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BD64_RS06165	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BD64_RS06175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BD64_RS06200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BD64_RS06210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BD64_RS06215	COG1959	2 iron, 2 sulfur cluster binding
BD64_RS06220	COG1104	cysteine desulfurase activity
BD64_RS06225	COG0482	sulfurtransferase activity
BD64_RS06235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BD64_RS06255	COG0628	permease
BD64_RS06265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD64_RS06285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BD64_RS06290	COG4122	O-methyltransferase activity
BD64_RS06295	COG0826	peptidase U32
BD64_RS06300	COG0826	peptidase U32
BD64_RS06315	COG0768	penicillin binding
BD64_RS06340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD64_RS06345	COG0626	cystathionine gamma-synthase activity
BD64_RS06350	COG1454	alcohol dehydrogenase
BD64_RS06350	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS06360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS06400	COG2259	Doxx family
BD64_RS06405	COG2514	catechol 2,3-dioxygenase activity
BD64_RS06410	COG2514	catechol 2,3-dioxygenase activity
BD64_RS06420	COG3186	Phenylalanine-4-hydroxylase
BD64_RS06425	COG1404	Belongs to the peptidase S8 family
BD64_RS06460	COG2267	carboxylic ester hydrolase activity
BD64_RS06470	COG1785	Belongs to the alkaline phosphatase family
BD64_RS06480	COG2357	RelA SpoT domain protein
BD64_RS06485	COG0778	Nitroreductase
BD64_RS06495	COG1595	DNA-templated transcription, initiation
BD64_RS06520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BD64_RS06525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BD64_RS06535	COG1534	Rna-binding protein
BD64_RS06545	COG1713	HD superfamily hydrolase involved in NAD metabolism
BD64_RS06550	COG0799	negative regulation of ribosome biogenesis
BD64_RS06555	COG2226	methyltransferase
BD64_RS06560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_RS06565	COG1555	photosystem II stabilization
BD64_RS06565	COG1596	polysaccharide export
BD64_RS06570	COG2131	deaminase
BD64_RS06575	COG2333	competence protein COMEC
BD64_RS06575	COG0658	competence protein
BD64_RS06585	COG1466	dna polymerase III delta subunit
BD64_RS06610	COG1733	regulation of RNA biosynthetic process
BD64_RS06615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BD64_RS06645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BD64_RS06650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BD64_RS06655	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BD64_RS06660	COG1610	YqeY-like protein
BD64_RS06680	COG1702	phosphate starvation-inducible protein PhoH
BD64_RS06685	COG1480	7TM receptor with intracellular HD hydrolase
BD64_RS06695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BD64_RS06700	COG0295	cytidine deaminase activity
BD64_RS06705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BD64_RS06720	COG0517	IMP dehydrogenase activity
BD64_RS06740	COG0358	DNA primase activity
BD64_RS06745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BD64_RS06750	COG2010	Cytochrome c
BD64_RS06755	COG2384	SAM-dependent methyltransferase
BD64_RS06760	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BD64_RS06790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS06795	COG1121	(ABC) transporter
BD64_RS06800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BD64_RS06805	COG0735	belongs to the Fur family
BD64_RS06830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BD64_RS06835	COG0477	Major facilitator Superfamily
BD64_RS06840	COG0768	penicillin binding
BD64_RS06845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BD64_RS06850	COG0573	inorganic phosphate transmembrane transporter activity
BD64_RS06855	COG0581	inorganic phosphate transmembrane transporter activity
BD64_RS06865	COG0704	Plays a role in the regulation of phosphate uptake
BD64_RS06870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BD64_RS06875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BD64_RS06880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BD64_RS06885	COG4483	Protein conserved in bacteria
BD64_RS06890	COG1940	carbohydrate kinase activity
BD64_RS06900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS06925	COG0626	cystathionine gamma-synthase activity
BD64_RS06930	COG0626	cystathionine gamma-synthase activity
BD64_RS06940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BD64_RS06940	COG0646	methionine synthase
BD64_RS06945	COG0646	methionine synthase
BD64_RS06945	COG1410	methionine synthase
BD64_RS06950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BD64_RS06995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BD64_RS07000	COG1459	type II secretion system
BD64_RS07010	COG4970	Tfp pilus assembly protein FimT
BD64_RS07065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BD64_RS07095	COG1725	Transcriptional regulator
BD64_RS07100	COG1131	(ABC) transporter
BD64_RS07140	COG2076	Multidrug Resistance protein
BD64_RS07145	COG2076	Multidrug Resistance protein
BD64_RS07155	COG1609	Transcriptional regulator
BD64_RS07160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_RS07165	COG0095	Lipoate-protein ligase
BD64_RS07185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BD64_RS07195	COG3872	metal-dependent enzyme
BD64_RS07210	COG0006	proline dipeptidase activity
BD64_RS07235	COG3854	ATPases associated with a variety of cellular activities
BD64_RS07280	COG0511	ligase activity, forming carbon-carbon bonds
BD64_RS07285	COG0439	Biotin carboxylase
BD64_RS07290	COG1302	Protein conserved in bacteria
BD64_RS07315	COG0142	geranyltranstransferase activity
BD64_RS07325	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BD64_RS07335	COG0497	DNA recombination
BD64_RS07340	COG0750	zinc metalloprotease
BD64_RS07345	COG0745	RESPONSE REGULATOR receiver
BD64_RS07355	COG3093	addiction module antidote protein HigA
BD64_RS07360	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_RS07370	COG3829	transcription factor binding
BD64_RS07370	COG3290	protein histidine kinase activity
BD64_RS07380	COG0280	phosphate acetyltransferase
BD64_RS07395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BD64_RS07400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BD64_RS07405	COG0022	dehydrogenase e1 component
BD64_RS07410	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_RS07420	COG0772	Belongs to the SEDS family
BD64_RS07445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_RS07450	COG0765	amino acid transport
BD64_RS07455	COG1126	abc transporter atp-binding protein
BD64_RS07460	COG4129	membrane
BD64_RS07465	COG1376	ErfK ybiS ycfS ynhG family protein
BD64_RS07480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS07485	COG2195	Cleaves the N-terminal amino acid of tripeptides
BD64_RS07495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BD64_RS07515	COG1760	l-serine dehydratase
BD64_RS07520	COG1760	l-serine dehydratase
BD64_RS07525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_RS07535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS07540	COG0300	oxidoreductase activity
BD64_RS07555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BD64_RS07565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BD64_RS07585	COG1522	sequence-specific DNA binding
BD64_RS07595	COG0737	Belongs to the 5'-nucleotidase family
BD64_RS07600	COG1757	Na H antiporter
BD64_RS07610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BD64_RS07625	COG1073	alpha beta
BD64_RS07625	COG2226	methyltransferase
BD64_RS07630	COG4106	trans-aconitate 2-methyltransferase activity
BD64_RS07655	COG0307	riboflavin synthase, alpha
BD64_RS07660	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BD64_RS07660	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BD64_RS07675	COG1073	alpha beta
BD64_RS07680	COG0456	acetyltransferase
BD64_RS07690	COG2056	Na+-H+ antiporter family
BD64_RS07695	COG0596	Alpha beta hydrolase
BD64_RS07705	COG4085	toxin activity
BD64_RS07705	COG1525	nuclease
BD64_RS07705	COG0737	Belongs to the 5'-nucleotidase family
BD64_RS07715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_RS07715	COG0456	acetyltransferase
BD64_RS07720	COG0656	L-ascorbic acid biosynthetic process
BD64_RS07725	COG0667	Aldo Keto reductase
BD64_RS07745	COG1300	Membrane
BD64_RS07750	COG0735	belongs to the Fur family
BD64_RS07760	COG4974	Belongs to the 'phage' integrase family
BD64_RS07785	COG0598	Magnesium transport protein CorA
BD64_RS07800	COG1846	Transcriptional regulator
BD64_RS07820	COG1131	(ABC) transporter
BD64_RS07825	COG1725	Transcriptional regulator
BD64_RS07830	COG1686	Belongs to the peptidase S11 family
BD64_RS07850	COG0733	neurotransmitter:sodium symporter activity
BD64_RS07875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_RS07890	COG0697	spore germination
BD64_RS07895	COG0561	phosphatase activity
BD64_RS07900	COG4086	secreted protein
BD64_RS07905	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BD64_RS07915	COG0456	acetyltransferase
BD64_RS07920	COG1547	Domain of unknown function (DUF309)
BD64_RS07950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BD64_RS07960	COG2188	Transcriptional regulator
BD64_RS07970	COG3711	transcriptional antiterminator
BD64_RS07975	COG2190	(PTS) system
BD64_RS07975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_RS07975	COG1263	PTS System
BD64_RS08000	COG0778	Nitroreductase
BD64_RS08005	COG2199	diguanylate cyclase activity
BD64_RS08025	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BD64_RS08045	COG0436	Aminotransferase
BD64_RS08050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BD64_RS08060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BD64_RS08070	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS08075	COG1695	Transcriptional regulator
BD64_RS08115	COG0183	Belongs to the thiolase family
BD64_RS08155	COG3842	ATPase activity
BD64_RS08160	COG0366	Alpha amylase catalytic
BD64_RS08170	COG2182	Extracellular solute-binding protein
BD64_RS08175	COG1175	transmembrane transport
BD64_RS08180	COG3833	ABC-type maltose transport systems, permease component
BD64_RS08185	COG1609	Transcriptional regulator
BD64_RS08190	COG0436	Aminotransferase
BD64_RS08200	COG2205	protein histidine kinase activity
BD64_RS08210	COG3209	COG3209 Rhs family protein
BD64_RS08235	COG2814	Major facilitator Superfamily
BD64_RS08275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BD64_RS08285	COG1408	metallophosphoesterase
BD64_RS08290	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS08295	COG2200	EAL domain
BD64_RS08310	COG4703	Protein of unknown function (DUF1797)
BD64_RS08320	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BD64_RS08330	COG0517	IMP dehydrogenase activity
BD64_RS08335	COG0583	DNA-binding transcription factor activity
BD64_RS08355	COG0569	domain protein
BD64_RS08360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD64_RS08370	COG0561	phosphatase activity
BD64_RS08375	COG0242	peptide deformylase activity
BD64_RS08385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BD64_RS08390	COG0022	dehydrogenase e1 component
BD64_RS08395	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_RS08440	COG1982	Orn Lys Arg decarboxylase major
BD64_RS08460	COG0483	inositol monophosphate 1-phosphatase activity
BD64_RS08470	COG1217	gtp-binding protein TYPA
BD64_RS08485	COG4896	Protein conserved in bacteria
BD64_RS08495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BD64_RS08500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BD64_RS08510	COG0772	Belongs to the SEDS family
BD64_RS08515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BD64_RS08550	COG3336	cytochrome c oxidase
BD64_RS08565	COG2340	Cysteine-rich secretory protein family
BD64_RS08580	COG0406	alpha-ribazole phosphatase activity
BD64_RS08585	COG3679	Belongs to the UPF0342 family
BD64_RS08600	COG0742	ribosomal rna small subunit methyltransferase
BD64_RS08610	COG3314	Sporulation integral membrane protein YlbJ
BD64_RS08615	COG1752	Esterase of the alpha-beta hydrolase superfamily
BD64_RS08620	COG3480	Lon protease (S16) C-terminal proteolytic domain
BD64_RS08630	COG0582	viral genome integration into host DNA
BD64_RS08645	COG1396	sequence-specific DNA binding
BD64_RS08655	COG1396	sequence-specific DNA binding
BD64_RS08685	COG1484	DNA-dependent DNA replication
BD64_RS08710	COG1191	sigma factor activity
BD64_RS08720	COG0756	dUTP diphosphatase activity
BD64_RS08790	COG0582	viral genome integration into host DNA
BD64_RS08815	COG1802	Transcriptional regulator
BD64_RS08815	COG4626	Terminase
BD64_RS08910	COG4824	toxin secretion phage lysis holin
BD64_RS08960	COG1399	metal-binding, possibly nucleic acid-binding protein
BD64_RS08965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BD64_RS08980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BD64_RS08995	COG4839	cell division protein FtsL
BD64_RS09000	COG0768	penicillin binding
BD64_RS09005	COG0768	penicillin binding
BD64_RS09010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BD64_RS09025	COG0772	Belongs to the SEDS family
BD64_RS09035	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BD64_RS09040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BD64_RS09045	COG0849	cell division
BD64_RS09050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BD64_RS09060	COG1191	sigma factor activity
BD64_RS09065	COG1191	sigma factor activity
BD64_RS09070	COG1873	PFAM PRC-barrel domain
BD64_RS09075	COG1496	oxidoreductase activity
BD64_RS09080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BD64_RS09090	COG0762	integral membrane protein
BD64_RS09095	COG2302	S4 RNA-binding domain
BD64_RS09100	COG3599	regulation of cell shape
BD64_RS09120	COG0564	pseudouridine synthase activity
BD64_RS09185	COG3069	C4-dicarboxylate transmembrane transporter activity
BD64_RS09200	COG0006	proline dipeptidase activity
BD64_RS09210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BD64_RS09215	COG1561	YicC-like family, N-terminal region
BD64_RS09235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BD64_RS09240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BD64_RS09245	COG0242	peptide deformylase activity
BD64_RS09255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BD64_RS09255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BD64_RS09265	COG0631	protein serine/threonine phosphatase activity
BD64_RS09270	COG2815	serine threonine protein kinase
BD64_RS09270	COG0515	serine threonine protein kinase
BD64_RS09275	COG1162	GTPase activity
BD64_RS09280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BD64_RS09285	COG1564	THIamine pyrophosphokinase
BD64_RS09300	COG1302	Protein conserved in bacteria
BD64_RS09305	COG1461	Dihydroxyacetone kinase
BD64_RS09310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BD64_RS09325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BD64_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS09335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BD64_RS09345	COG1196	nuclear chromosome segregation
BD64_RS09350	COG0552	protein localization to endoplasmic reticulum
BD64_RS09360	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BD64_RS09370	COG1837	Belongs to the UPF0109 family
BD64_RS09410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BD64_RS09420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BD64_RS09430	COG4974	Belongs to the 'phage' integrase family
BD64_RS09460	COG0528	UMP kinase activity
BD64_RS09470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BD64_RS09475	COG4589	Belongs to the CDS family
BD64_RS09485	COG0750	zinc metalloprotease
BD64_RS09505	COG0195	Participates in both transcription termination and antitermination
BD64_RS09510	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BD64_RS09515	COG1358	cellular component organization or biogenesis
BD64_RS09525	COG1550	Protein conserved in bacteria
BD64_RS09535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BD64_RS09540	COG0196	riboflavin kinase activity
BD64_RS09555	COG0726	polysaccharide deacetylase
BD64_RS09560	COG0612	Peptidase, M16
BD64_RS09565	COG1873	PFAM PRC-barrel domain
BD64_RS09570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD64_RS09575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BD64_RS09580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BD64_RS09585	COG0527	aspartate kinase activity
BD64_RS09600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD64_RS09605	COG0740	serine-type endopeptidase activity
BD64_RS09615	COG1674	ftsk spoiiie
BD64_RS09620	COG2188	Transcriptional regulator
BD64_RS09625	COG1744	ABC transporter substrate-binding protein PnrA-like
BD64_RS09630	COG3845	ABC transporter
BD64_RS09635	COG4603	Belongs to the binding-protein-dependent transport system permease family
BD64_RS09640	COG4603	Belongs to the binding-protein-dependent transport system permease family
BD64_RS09645	COG1079	Belongs to the binding-protein-dependent transport system permease family
BD64_RS09650	COG0612	Peptidase, M16
BD64_RS09655	COG0612	Peptidase, M16
BD64_RS09660	COG0300	oxidoreductase activity
BD64_RS09675	COG1426	Protein conserved in bacteria
BD64_RS09680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BD64_RS09705	COG1692	metallophosphoesterase
BD64_RS09710	COG2359	stage V sporulation protein S
BD64_RS09720	COG0674	pyruvate-flavodoxin oxidoreductase activity
BD64_RS09720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BD64_RS09725	COG1013	pyruvate-flavodoxin oxidoreductase activity
BD64_RS09730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BD64_RS09735	COG4550	Control of competence regulator ComK, YlbF/YmcA
BD64_RS09755	COG1131	(ABC) transporter
BD64_RS09780	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BD64_RS09790	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BD64_RS09795	COG1368	sulfuric ester hydrolase activity
BD64_RS09800	COG0562	UDP-galactopyranose mutase
BD64_RS09805	COG3773	Cell wall hydrolase
BD64_RS09810	COG1404	Belongs to the peptidase S8 family
BD64_RS09825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BD64_RS09830	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_RS09830	COG0596	Alpha beta hydrolase
BD64_RS09835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS09840	COG1380	Effector of murein hydrolase LrgA
BD64_RS09845	COG1346	cytolysis
BD64_RS09865	COG5001	Diguanylate cyclase
BD64_RS09865	COG3300	MHYT domain
BD64_RS09870	COG0346	lactoylglutathione lyase activity
BD64_RS09875	COG2267	carboxylic ester hydrolase activity
BD64_RS09890	COG2364	Membrane
BD64_RS09900	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BD64_RS09905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BD64_RS09910	COG2169	Transcriptional regulator
BD64_RS09915	COG0708	Exodeoxyribonuclease III
BD64_RS09925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS09930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS09935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS09940	COG1120	ATPase activity
BD64_RS09945	COG2819	hydrolase of the alpha beta superfamily
BD64_RS09955	COG1937	Protein conserved in bacteria
BD64_RS09960	COG2608	mercury ion transmembrane transporter activity
BD64_RS09965	COG2217	Heavy metal translocating P-type atpase
BD64_RS09975	COG2116	formate transmembrane transporter activity
BD64_RS09980	COG1408	metallophosphoesterase
BD64_RS09990	COG1113	amino acid transport
BD64_RS10005	COG2322	membrane
BD64_RS10015	COG1349	DNA-binding transcription factor activity
BD64_RS10020	COG1105	Belongs to the carbohydrate kinase PfkB family
BD64_RS10025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BD64_RS10025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BD64_RS10025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BD64_RS10030	COG3584	3D domain protein
BD64_RS10030	COG1388	LysM domain
BD64_RS10060	COG0464	growth
BD64_RS10065	COG2860	membrane
BD64_RS10075	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BD64_RS10080	COG0789	Transcriptional regulator
BD64_RS10085	COG0174	glutamine synthetase
BD64_RS10110	COG1396	sequence-specific DNA binding
BD64_RS10205	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BD64_RS10250	COG1595	DNA-templated transcription, initiation
BD64_RS10410	COG4824	toxin secretion phage lysis holin
BD64_RS10415	COG1388	LysM domain
BD64_RS10415	COG5632	N-Acetylmuramoyl-L-alanine amidase
BD64_RS10415	COG3409	Peptidoglycan-binding domain 1 protein
BD64_RS10450	COG1695	Transcriptional regulator
BD64_RS10470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BD64_RS10480	COG0737	Belongs to the 5'-nucleotidase family
BD64_RS10495	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BD64_RS10500	COG3639	organic phosphonate transmembrane transporter activity
BD64_RS10535	COG1132	(ABC) transporter
BD64_RS10540	COG1132	(ABC) transporter
BD64_RS10555	COG5632	N-Acetylmuramoyl-L-alanine amidase
BD64_RS10555	COG3409	Peptidoglycan-binding domain 1 protein
BD64_RS10565	COG0730	response to heat
BD64_RS10580	COG1346	cytolysis
BD64_RS10585	COG1380	Effector of murein hydrolase LrgA
BD64_RS10590	COG0583	DNA-binding transcription factor activity
BD64_RS10600	COG0785	Cytochrome C biogenesis protein
BD64_RS10605	COG4846	Membrane protein involved in cytochrome C biogenesis
BD64_RS10660	COG2226	methyltransferase
BD64_RS10685	COG0010	Belongs to the arginase family
BD64_RS10690	COG1329	Transcriptional regulator
BD64_RS10695	COG1902	pentaerythritol trinitrate reductase activity
BD64_RS10700	COG0069	glutamate synthase activity
BD64_RS10705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_RS10710	COG0346	lactoylglutathione lyase activity
BD64_RS10715	COG0400	carboxylic ester hydrolase activity
BD64_RS10720	COG5002	protein histidine kinase activity
BD64_RS10730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS10775	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_RS10780	COG1268	BioY protein
BD64_RS10785	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_RS10790	COG0183	Belongs to the thiolase family
BD64_RS10805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD64_RS10815	COG2211	Major facilitator Superfamily
BD64_RS10845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BD64_RS10850	COG2274	protein secretion by the type I secretion system
BD64_RS10860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_RS10890	COG0824	Thioesterase
BD64_RS10895	COG4841	protein insertion into membrane
BD64_RS10900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BD64_RS10915	COG0745	RESPONSE REGULATOR receiver
BD64_RS10920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD64_RS10925	COG1832	CoA-binding protein
BD64_RS10935	COG0187	DNA topoisomerase II activity
BD64_RS10940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BD64_RS10945	COG0673	inositol 2-dehydrogenase activity
BD64_RS10955	COG1131	(ABC) transporter
BD64_RS10980	COG1595	DNA-templated transcription, initiation
BD64_RS10990	COG1316	TRANSCRIPTIONal
BD64_RS10995	COG1301	dicarboxylic acid transport
BD64_RS11000	COG4166	transmembrane transport
BD64_RS11005	COG4166	transmembrane transport
BD64_RS11010	COG4166	transmembrane transport
BD64_RS11015	COG2226	methyltransferase
BD64_RS11055	COG0697	spore germination
BD64_RS11070	COG2427	Protein of unknown function (DUF1641)
BD64_RS11075	COG5609	conserved protein (DUF2294)
BD64_RS11080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BD64_RS11090	COG2116	formate transmembrane transporter activity
BD64_RS11095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_RS11100	COG0303	'Molybdopterin
BD64_RS11105	COG0314	molybdopterin synthase activity
BD64_RS11115	COG0489	protein tyrosine kinase activity
BD64_RS11130	COG3326	Membrane
BD64_RS11135	COG2962	Rard protein
BD64_RS11140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BD64_RS11145	COG1657	PFAM Prenyltransferase squalene oxidase
BD64_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS11160	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS11170	COG4145	pantothenate transmembrane transporter activity
BD64_RS11185	COG0165	Argininosuccinate lyase
BD64_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS11225	COG0716	FMN binding
BD64_RS11265	COG2720	vancomycin resistance protein
BD64_RS11270	COG2514	catechol 2,3-dioxygenase activity
BD64_RS11280	COG1285	pathogenesis
BD64_RS11290	COG1024	Enoyl-CoA hydratase
BD64_RS11295	COG1216	Glycosyl transferase, family 2
BD64_RS11325	COG0277	FAD linked oxidase domain protein
BD64_RS11330	COG0385	Bile acid
BD64_RS11340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_RS11345	COG2808	Putative FMN-binding domain
BD64_RS11365	COG0604	alcohol dehydrogenase
BD64_RS11370	COG0640	Transcriptional regulator
BD64_RS11395	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_RS11425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_RS11435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BD64_RS11450	COG1193	negative regulation of DNA recombination
BD64_RS11470	COG0583	DNA-binding transcription factor activity
BD64_RS11500	COG0384	phenazine biosynthesis protein PhzF
BD64_RS11505	COG3739	integral membrane protein
BD64_RS11510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS11515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS11525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS11545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD64_RS11550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BD64_RS11585	COG2814	Major facilitator Superfamily
BD64_RS11590	COG1113	amino acid transport
BD64_RS11595	COG0604	alcohol dehydrogenase
BD64_RS11630	COG2072	flavoprotein involved in K transport
BD64_RS11665	COG3409	Peptidoglycan-binding domain 1 protein
BD64_RS11665	COG3757	hydrolase, family 25
BD64_RS11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS11680	COG1151	hydroxylamine reductase activity
BD64_RS11705	COG3152	Membrane
BD64_RS11725	COG1309	transcriptional regulator
BD64_RS11740	COG1191	sigma factor activity
BD64_RS11775	COG1733	regulation of RNA biosynthetic process
BD64_RS11785	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS11805	COG0384	phenazine biosynthesis protein PhzF
BD64_RS11825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS11840	COG1733	regulation of RNA biosynthetic process
BD64_RS11845	COG1733	regulation of RNA biosynthetic process
BD64_RS11850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BD64_RS11860	COG2188	Transcriptional regulator
BD64_RS11865	COG1733	regulation of RNA biosynthetic process
BD64_RS11875	COG1393	Belongs to the ArsC family
BD64_RS11900	COG0814	amino acid
BD64_RS11905	COG0346	lactoylglutathione lyase activity
BD64_RS11920	COG2814	Major facilitator Superfamily
BD64_RS11925	COG0656	L-ascorbic acid biosynthetic process
BD64_RS11950	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS11960	COG3321	synthase
BD64_RS11960	COG0604	alcohol dehydrogenase
BD64_RS11970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BD64_RS11975	COG0604	alcohol dehydrogenase
BD64_RS11980	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BD64_RS11985	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BD64_RS11995	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BD64_RS12000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BD64_RS12010	COG1070	Carbohydrate kinase
BD64_RS12015	COG2706	6-phosphogluconolactonase activity
BD64_RS12020	COG3813	Protein conserved in bacteria
BD64_RS12025	COG1357	PFAM Pentapeptide repeats (8 copies)
BD64_RS12030	COG0697	spore germination
BD64_RS12035	COG0789	Transcriptional regulator
BD64_RS12040	COG1253	flavin adenine dinucleotide binding
BD64_RS12070	COG0477	Major facilitator Superfamily
BD64_RS12080	COG2226	methyltransferase
BD64_RS12100	COG0628	permease
BD64_RS12105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BD64_RS12115	COG0577	efflux transmembrane transporter activity
BD64_RS12115	COG1136	(ABC) transporter
BD64_RS12125	COG0110	maltose O-acetyltransferase activity
BD64_RS12130	COG0738	Major facilitator superfamily
BD64_RS12135	COG1940	carbohydrate kinase activity
BD64_RS12140	COG0346	lactoylglutathione lyase activity
BD64_RS12165	COG2365	Tyrosine phosphatase family
BD64_RS12175	COG1011	Hydrolase
BD64_RS12200	COG1131	(ABC) transporter
BD64_RS12210	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS12230	COG0778	Nitroreductase
BD64_RS12235	COG1733	regulation of RNA biosynthetic process
BD64_RS12250	COG0124	histidyl-tRNA synthetase
BD64_RS12255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BD64_RS12260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BD64_RS12265	COG3620	sequence-specific DNA binding
BD64_RS12280	COG2356	endonuclease I
BD64_RS12285	COG1288	antiporter activity
BD64_RS12290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BD64_RS12305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BD64_RS12310	COG1122	ATPase activity
BD64_RS12340	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_RS12350	COG2031	fatty acid transporter
BD64_RS12365	COG1309	transcriptional regulator
BD64_RS12370	COG2076	Multidrug Resistance protein
BD64_RS12390	COG1131	(ABC) transporter
BD64_RS12395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BD64_RS12410	COG2814	Major facilitator Superfamily
BD64_RS12415	COG1846	Transcriptional regulator
BD64_RS12425	COG0477	Major facilitator Superfamily
BD64_RS12480	COG2207	Transcriptional regulator
BD64_RS12480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS12490	COG0662	Cupin 2, conserved barrel domain protein
BD64_RS12505	COG1595	DNA-templated transcription, initiation
BD64_RS12525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BD64_RS12540	COG0531	amino acid
BD64_RS12545	COG1522	sequence-specific DNA binding
BD64_RS12550	COG1335	isochorismatase
BD64_RS12560	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BD64_RS12565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BD64_RS12575	COG1760	l-serine dehydratase
BD64_RS12580	COG1760	l-serine dehydratase
BD64_RS12585	COG0814	amino acid
BD64_RS12600	COG1309	transcriptional regulator
BD64_RS12605	COG2814	Major facilitator Superfamily
BD64_RS12625	COG0534	Mate efflux family protein
BD64_RS12655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BD64_RS12675	COG0457	Tetratricopeptide repeat
BD64_RS12680	COG1609	Transcriptional regulator
BD64_RS12690	COG0561	phosphatase activity
BD64_RS12695	COG0673	inositol 2-dehydrogenase activity
BD64_RS12700	COG0738	Major facilitator superfamily
BD64_RS12725	COG1619	proteins homologs of microcin C7 resistance protein MccF
BD64_RS12735	COG0583	DNA-binding transcription factor activity
BD64_RS12745	COG1139	Iron-sulfur cluster binding protein
BD64_RS12750	COG1556	Lactate utilization protein
BD64_RS12755	COG2271	Major facilitator Superfamily
BD64_RS12760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS12765	COG2808	Putative FMN-binding domain
BD64_RS12775	COG1846	Transcriptional regulator
BD64_RS12780	COG2364	Membrane
BD64_RS12790	COG3850	Histidine kinase
BD64_RS12790	COG5002	protein histidine kinase activity
BD64_RS12810	COG0577	efflux transmembrane transporter activity
BD64_RS12815	COG1136	(ABC) transporter
BD64_RS12830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BD64_RS12835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_RS12845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD64_RS12850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS12865	COG1476	TRANSCRIPTIONal
BD64_RS12890	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BD64_RS12920	COG5002	protein histidine kinase activity
BD64_RS12920	COG3850	Histidine kinase
BD64_RS12925	COG0745	RESPONSE REGULATOR receiver
BD64_RS12950	COG2814	Major facilitator Superfamily
BD64_RS12995	COG2169	Transcriptional regulator
BD64_RS13020	COG0346	lactoylglutathione lyase activity
BD64_RS13035	COG1522	sequence-specific DNA binding
BD64_RS13050	COG0443	Heat shock 70 kDa protein
BD64_RS13065	COG0640	Transcriptional regulator
BD64_RS13070	COG0346	lactoylglutathione lyase activity
BD64_RS13075	COG0798	PFAM Bile acid sodium symporter
BD64_RS13105	COG1121	(ABC) transporter
BD64_RS13110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BD64_RS13115	COG0803	Belongs to the bacterial solute-binding protein 9 family
BD64_RS13120	COG2267	carboxylic ester hydrolase activity
BD64_RS13125	COG1575	Belongs to the MenA family. Type 1 subfamily
BD64_RS13135	COG5609	conserved protein (DUF2294)
BD64_RS13140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD64_RS13150	COG0288	reversible hydration of carbon dioxide
BD64_RS13155	COG0415	Belongs to the DNA photolyase family
BD64_RS13200	COG0583	DNA-binding transcription factor activity
BD64_RS13225	COG1335	isochorismatase
BD64_RS13230	COG2267	carboxylic ester hydrolase activity
BD64_RS13235	COG0753	catalase activity
BD64_RS13240	COG0737	Belongs to the 5'-nucleotidase family
BD64_RS13265	COG1115	amino acid carrier protein
BD64_RS13270	COG2066	Belongs to the glutaminase family
BD64_RS13280	COG0784	Response regulator, receiver
BD64_RS13285	COG0697	spore germination
BD64_RS13290	COG0531	amino acid
BD64_RS13310	COG0281	malic enzyme
BD64_RS13320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_RS13325	COG1114	Component of the transport system for branched-chain amino acids
BD64_RS13330	COG0531	amino acid
BD64_RS13335	COG0322	excinuclease ABC activity
BD64_RS13345	COG1396	sequence-specific DNA binding
BD64_RS13350	COG0252	asparaginase activity
BD64_RS13355	COG1027	Aspartate ammonia-lyase
BD64_RS13370	COG1063	alcohol dehydrogenase
BD64_RS13405	COG1280	lysine exporter protein (LysE YggA)
BD64_RS13410	COG3403	YqcI/YcgG family
BD64_RS13415	COG5577	PFAM Coat F domain
BD64_RS13430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS13435	COG3848	Pyruvate phosphate dikinase
BD64_RS13435	COG0574	Belongs to the PEP-utilizing enzyme family
BD64_RS13450	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BD64_RS13465	COG3314	Sporulation integral membrane protein YlbJ
BD64_RS13485	COG1960	acyl-CoA dehydrogenase activity
BD64_RS13495	COG0640	Transcriptional regulator
BD64_RS13500	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_RS13515	COG1414	Transcriptional regulator
BD64_RS13520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BD64_RS13555	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BD64_RS13565	COG0768	penicillin binding
BD64_RS13605	COG4335	DNA alkylation repair
BD64_RS13615	COG0833	amino acid
BD64_RS13625	COG0730	response to heat
BD64_RS13655	COG0596	Alpha beta hydrolase
BD64_RS13660	COG0745	RESPONSE REGULATOR receiver
BD64_RS13665	COG0642	Histidine kinase
BD64_RS13685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS13705	COG0456	acetyltransferase
BD64_RS13710	COG2207	Transcriptional regulator
BD64_RS13735	COG0577	efflux transmembrane transporter activity
BD64_RS13735	COG1136	(ABC) transporter
BD64_RS13745	COG1725	Transcriptional regulator
BD64_RS13780	COG1846	Transcriptional regulator
BD64_RS13785	COG0778	Nitroreductase
BD64_RS13795	COG0714	Associated with various cellular activities
BD64_RS13820	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BD64_RS13830	COG0753	catalase activity
BD64_RS13835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BD64_RS13845	COG0463	Glycosyl transferase, family 2
BD64_RS13870	COG0463	Glycosyl transferase, family 2
BD64_RS13895	COG0714	Associated with various cellular activities
BD64_RS13915	COG0346	lactoylglutathione lyase activity
BD64_RS13920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS13930	COG3279	Response regulator of the LytR AlgR family
BD64_RS13940	COG4377	Putative membrane peptidase family (DUF2324)
BD64_RS13955	COG3655	Transcriptional regulator
BD64_RS13965	COG1785	Belongs to the alkaline phosphatase family
BD64_RS13970	COG3239	Fatty acid desaturase
BD64_RS13975	COG1690	Belongs to the RtcB family
BD64_RS13980	COG0833	amino acid
BD64_RS13985	COG1414	Transcriptional regulator
BD64_RS13990	COG4187	Peptidase family M20/M25/M40
BD64_RS13995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_RS14000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BD64_RS14010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS14030	COG2329	Antibiotic biosynthesis monooxygenase
BD64_RS14065	COG2390	Transcriptional regulator
BD64_RS14075	COG1172	Belongs to the binding-protein-dependent transport system permease family
BD64_RS14085	COG1879	ABC-type sugar transport system periplasmic component
BD64_RS14110	COG1595	DNA-templated transcription, initiation
BD64_RS14120	COG1388	LysM domain
BD64_RS14120	COG3584	3D domain protein
BD64_RS14155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BD64_RS14155	COG1605	Chorismate mutase
BD64_RS14160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BD64_RS14165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BD64_RS14170	COG0287	Prephenate dehydrogenase
BD64_RS14185	COG1309	transcriptional regulator
BD64_RS14190	COG2409	Drug exporters of the RND superfamily
BD64_RS14190	COG1033	growth of symbiont in host cell
BD64_RS14195	COG1033	growth of symbiont in host cell
BD64_RS14195	COG2409	Drug exporters of the RND superfamily
BD64_RS14200	COG1033	growth of symbiont in host cell
BD64_RS14200	COG2409	Drug exporters of the RND superfamily
BD64_RS14210	COG0488	(ABC) transporter
BD64_RS14215	COG1368	sulfuric ester hydrolase activity
BD64_RS14220	COG0861	Integral membrane protein TerC family
BD64_RS14240	COG4912	Dna alkylation repair
BD64_RS14260	COG2318	DinB family
BD64_RS14265	COG0697	spore germination
BD64_RS14290	COG2746	aminoglycoside 3-N-acetyltransferase activity
BD64_RS14310	COG2816	NAD+ diphosphatase activity
BD64_RS14330	COG1116	anion transmembrane transporter activity
BD64_RS14335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BD64_RS14340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_RS14345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BD64_RS14360	COG0628	permease
BD64_RS14410	COG1131	(ABC) transporter
BD64_RS14430	COG5146	pantothenate kinase activity
BD64_RS14435	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BD64_RS14440	COG0436	Aminotransferase
BD64_RS14475	COG2226	methyltransferase
BD64_RS14490	COG2261	transglycosylase associated protein
BD64_RS14510	COG0477	Major facilitator Superfamily
BD64_RS14510	COG2814	Major facilitator Superfamily
BD64_RS14515	COG4533	DNA binding
BD64_RS14520	COG0789	Transcriptional regulator
BD64_RS14525	COG1664	Polymer-forming cytoskeletal
BD64_RS14535	COG2814	Major facilitator Superfamily
BD64_RS14555	COG1307	EDD domain protein, DegV family
BD64_RS14595	COG0745	RESPONSE REGULATOR receiver
BD64_RS14600	COG5002	protein histidine kinase activity
BD64_RS14605	COG2936	dipeptidyl-peptidase activity
BD64_RS14645	COG4948	Mandelate Racemase Muconate Lactonizing
BD64_RS14655	COG4166	transmembrane transport
BD64_RS14660	COG0519	Catalyzes the synthesis of GMP from XMP
BD64_RS14665	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BD64_RS14680	COG0586	Pfam SNARE associated Golgi protein
BD64_RS14720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_RS14725	COG3938	Belongs to the proline racemase family
BD64_RS14735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BD64_RS14740	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS14745	COG1115	amino acid carrier protein
BD64_RS14750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BD64_RS14760	COG3397	chitin binding
BD64_RS14785	COG4637	Psort location Cytoplasmic, score
BD64_RS14815	COG0514	ATP-dependent DNA helicase (RecQ)
BD64_RS14820	COG2105	PFAM AIG2 family protein
BD64_RS14835	COG3973	AAA domain
BD64_RS14885	COG0658	competence protein
BD64_RS14885	COG2333	competence protein COMEC
BD64_RS14915	COG2205	protein histidine kinase activity
BD64_RS14930	COG3397	chitin binding
BD64_RS14935	COG2153	protein acetylation
BD64_RS14940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BD64_RS14965	COG4175	Glycine betaine
BD64_RS14965	COG0517	IMP dehydrogenase activity
BD64_RS14970	COG4176	ABC-type proline glycine betaine transport system permease component
BD64_RS15005	COG0456	acetyltransferase
BD64_RS15005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_RS15010	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS15020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BD64_RS15025	COG0022	dehydrogenase e1 component
BD64_RS15030	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_RS15035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BD64_RS15050	COG1959	2 iron, 2 sulfur cluster binding
BD64_RS15070	COG1349	DNA-binding transcription factor activity
BD64_RS15090	COG3284	Transcriptional regulator
BD64_RS15120	COG1309	transcriptional regulator
BD64_RS15125	COG3844	kynureninase activity
BD64_RS15130	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BD64_RS15135	COG3483	tryptophan 2,3-dioxygenase activity
BD64_RS15155	COG2959	enzyme of heme biosynthesis
BD64_RS15170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS15175	COG4129	membrane
BD64_RS15205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS15210	COG0697	spore germination
BD64_RS15220	COG0201	protein transport
BD64_RS15240	COG3227	Zinc metalloprotease (Elastase)
BD64_RS15245	COG1523	belongs to the glycosyl hydrolase 13 family
BD64_RS15260	COG0076	glutamate decarboxylase activity
BD64_RS15280	COG1011	Hydrolase
BD64_RS15305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_RS15345	COG0322	excinuclease ABC activity
BD64_RS15360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BD64_RS15385	COG4667	esterase of the alpha-beta hydrolase superfamily
BD64_RS15415	COG3878	Protein conserved in bacteria
BD64_RS15450	COG1051	belongs to the nudix hydrolase family
BD64_RS15455	COG0592	DNA-directed DNA polymerase activity
BD64_RS15460	COG2816	NAD+ diphosphatase activity
BD64_RS15475	COG2223	nitrite transmembrane transporter activity
BD64_RS15485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_RS15510	COG0697	spore germination
BD64_RS15530	COG0584	glycerophosphoryl diester phosphodiesterase
BD64_RS15545	COG2814	Major facilitator Superfamily
BD64_RS15575	COG0693	protein deglycase activity
BD64_RS15610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_RS15620	COG0768	penicillin binding
BD64_RS15625	COG0604	alcohol dehydrogenase
BD64_RS15630	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BD64_RS15640	COG2205	protein histidine kinase activity
BD64_RS15650	COG1122	ATPase activity
BD64_RS15660	COG1794	racemase activity, acting on amino acids and derivatives
BD64_RS15665	COG1819	glycosyl
BD64_RS15670	COG0768	penicillin binding
BD64_RS15675	COG5002	protein histidine kinase activity
BD64_RS15685	COG0561	phosphatase activity
BD64_RS15720	COG2124	cytochrome p450
BD64_RS15795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BD64_RS15805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS15810	COG0460	homoserine dehydrogenase
BD64_RS15835	COG1136	(ABC) transporter
BD64_RS15850	COG0488	(ABC) transporter
BD64_RS15875	COG3773	Cell wall hydrolase
BD64_RS15890	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BD64_RS15895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BD64_RS15910	COG1063	alcohol dehydrogenase
BD64_RS15925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS15945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BD64_RS15965	COG2814	Major facilitator Superfamily
BD64_RS15990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BD64_RS15990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BD64_RS16030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BD64_RS16055	COG1686	Belongs to the peptidase S11 family
BD64_RS16060	COG2318	DinB family
BD64_RS16070	COG0572	uridine kinase
BD64_RS16075	COG1247	-acetyltransferase
BD64_RS16085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD64_RS16090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BD64_RS16095	COG1024	Enoyl-CoA hydratase
BD64_RS16100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BD64_RS16105	COG0511	ligase activity, forming carbon-carbon bonds
BD64_RS16110	COG0439	Biotin carboxylase
BD64_RS16115	COG1960	acyl-CoA dehydrogenase activity
BD64_RS16130	COG1309	transcriptional regulator
BD64_RS16140	COG1131	(ABC) transporter
BD64_RS16155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_RS16160	COG1252	NADH dehydrogenase
BD64_RS16170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS16185	COG0488	(ABC) transporter
BD64_RS16190	COG1309	transcriptional regulator
BD64_RS16210	COG1876	peptidase activity
BD64_RS16225	COG1476	TRANSCRIPTIONal
BD64_RS16230	COG0457	Tetratricopeptide repeat
BD64_RS16260	COG3718	enzyme involved in inositol metabolism
BD64_RS16265	COG0191	fructose-bisphosphate aldolase activity
BD64_RS16280	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS16290	COG0673	inositol 2-dehydrogenase activity
BD64_RS16295	COG2814	Major facilitator Superfamily
BD64_RS16300	COG1609	Transcriptional regulator
BD64_RS16305	COG0671	phosphoesterase, PA-phosphatase related
BD64_RS16310	COG2367	Beta-lactamase
BD64_RS16320	COG0768	penicillin binding
BD64_RS16330	COG1595	DNA-templated transcription, initiation
BD64_RS16345	COG2195	Cleaves the N-terminal amino acid of tripeptides
BD64_RS16385	COG1846	Transcriptional regulator
BD64_RS16390	COG3961	Belongs to the TPP enzyme family
BD64_RS16395	COG2226	methyltransferase
BD64_RS16405	COG0500	methyltransferase
BD64_RS16405	COG3615	Tellurite resistance protein tehB
BD64_RS16410	COG1136	(ABC) transporter
BD64_RS16410	COG0577	efflux transmembrane transporter activity
BD64_RS16425	COG1309	transcriptional regulator
BD64_RS16455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS16475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BD64_RS16480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BD64_RS16485	COG2971	BadF BadG BcrA BcrD
BD64_RS16510	COG1649	PFAM Uncharacterised BCR, COG1649
BD64_RS16535	COG1595	DNA-templated transcription, initiation
BD64_RS16540	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BD64_RS16565	COG1396	sequence-specific DNA binding
BD64_RS16585	COG1132	(ABC) transporter
BD64_RS16590	COG1132	(ABC) transporter
BD64_RS16605	COG2258	MOSC domain
BD64_RS16610	COG0583	DNA-binding transcription factor activity
BD64_RS16625	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BD64_RS16630	COG0583	DNA-binding transcription factor activity
BD64_RS16675	COG0561	phosphatase activity
BD64_RS16680	COG0010	Belongs to the arginase family
BD64_RS16695	COG1278	Cold shock
BD64_RS16705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS16715	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BD64_RS16745	COG1247	-acetyltransferase
BD64_RS16780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS16825	COG2226	methyltransferase
BD64_RS16845	COG2814	Major facilitator Superfamily
BD64_RS16850	COG0596	Alpha beta hydrolase
BD64_RS16865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD64_RS16870	COG1187	pseudouridine synthase activity
BD64_RS16875	COG2329	Antibiotic biosynthesis monooxygenase
BD64_RS16895	COG1115	amino acid carrier protein
BD64_RS16905	COG2318	DinB family
BD64_RS16915	COG0776	regulation of translation
BD64_RS16930	COG2814	Major facilitator Superfamily
BD64_RS16935	COG3251	PFAM MbtH domain protein
BD64_RS16940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BD64_RS16945	COG1535	isochorismatase
BD64_RS16945	COG3433	isochorismatase activity
BD64_RS16950	COG1021	2,3-dihydroxybenzoate-AMP ligase
BD64_RS16955	COG1169	isochorismate synthase
BD64_RS16960	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS16965	COG2223	nitrite transmembrane transporter activity
BD64_RS16995	COG0419	ATPase involved in DNA repair
BD64_RS17000	COG0420	3'-5' exonuclease activity
BD64_RS17015	COG1024	Enoyl-CoA hydratase
BD64_RS17020	COG1280	lysine exporter protein (LysE YggA)
BD64_RS17030	COG2084	Dehydrogenase
BD64_RS17035	COG1960	acyl-CoA dehydrogenase activity
BD64_RS17040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BD64_RS17045	COG2079	MmgE PrpD family protein
BD64_RS17050	COG0372	Belongs to the citrate synthase family
BD64_RS17055	COG4841	protein insertion into membrane
BD64_RS17065	COG4499	WXG100 protein secretion system (Wss), protein YukC
BD64_RS17065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_RS17105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BD64_RS17195	COG1715	Restriction endonuclease
BD64_RS17195	COG1787	Restriction endonuclease
BD64_RS17225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_RS17230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BD64_RS17235	COG0671	phosphoesterase, PA-phosphatase related
BD64_RS17240	COG4326	sporulation control protein
BD64_RS17280	COG1509	lysine 2,3-aminomutase activity
BD64_RS17285	COG3829	transcription factor binding
BD64_RS17290	COG0456	acetyltransferase
BD64_RS17295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_RS17300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BD64_RS17305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BD64_RS17310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BD64_RS17325	COG5506	Protein of unknown function (DUF1694)
BD64_RS17330	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS17335	COG1253	flavin adenine dinucleotide binding
BD64_RS17370	COG1174	glycine betaine transport
BD64_RS17375	COG0517	IMP dehydrogenase activity
BD64_RS17375	COG1125	glycine betaine transport
BD64_RS17405	COG1070	Carbohydrate kinase
BD64_RS17410	COG1070	Carbohydrate kinase
BD64_RS17440	COG1064	alcohol dehydrogenase
BD64_RS17445	COG1737	Transcriptional regulator
BD64_RS17455	COG2197	response regulator
BD64_RS17460	COG4585	Histidine kinase
BD64_RS17460	COG2203	Gaf domain
BD64_RS17465	COG0668	transmembrane transport
BD64_RS17500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_RS17505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS17525	COG0367	asparagine synthase
BD64_RS17530	COG0071	Belongs to the small heat shock protein (HSP20) family
BD64_RS17535	COG1999	signal sequence binding
BD64_RS17540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BD64_RS17545	COG1307	EDD domain protein, DegV family
BD64_RS17555	COG0805	protein transport
BD64_RS17565	COG1272	protein, Hemolysin III
BD64_RS17570	COG0204	Acyl-transferase
BD64_RS17575	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BD64_RS17580	COG0768	penicillin binding
BD64_RS17595	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_RS17615	COG0546	phosphoglycolate phosphatase activity
BD64_RS17625	COG4473	ABC transporter
BD64_RS17630	COG1131	(ABC) transporter
BD64_RS17645	COG0456	acetyltransferase
BD64_RS17655	COG1794	racemase activity, acting on amino acids and derivatives
BD64_RS17660	COG1454	alcohol dehydrogenase
BD64_RS17665	COG2610	gluconate transmembrane transporter activity
BD64_RS17690	COG0733	neurotransmitter:sodium symporter activity
BD64_RS17705	COG5002	protein histidine kinase activity
BD64_RS17705	COG3850	Histidine kinase
BD64_RS17710	COG0745	RESPONSE REGULATOR receiver
BD64_RS17715	COG0471	metal ion transport
BD64_RS17720	COG1929	Belongs to the glycerate kinase type-1 family
BD64_RS17815	COG1674	ftsk spoiiie
BD64_RS17835	COG0017	Asparaginyl-tRNA synthetase
BD64_RS17840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BD64_RS17855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BD64_RS17880	COG0018	arginyl-trna synthetase
BD64_RS17885	COG2521	methyltransferase
BD64_RS17885	COG2136	Putative SAM-dependent methyltransferase
BD64_RS17900	COG1413	lyase activity
BD64_RS17905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BD64_RS17920	COG0629	single-stranded DNA binding
BD64_RS17935	COG0488	(ABC) transporter
BD64_RS17940	COG1418	mRNA catabolic process
BD64_RS17955	COG5632	N-Acetylmuramoyl-L-alanine amidase
BD64_RS17970	COG2359	stage V sporulation protein S
BD64_RS18005	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BD64_RS18010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BD64_RS18015	COG2146	nitrite reductase [NAD(P)H] activity
BD64_RS18020	COG1587	Uroporphyrinogen-III synthase
BD64_RS18020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BD64_RS18030	COG1648	precorrin-2 dehydrogenase activity
BD64_RS18045	COG2223	nitrite transmembrane transporter activity
BD64_RS18055	COG0314	molybdopterin synthase activity
BD64_RS18060	COG0303	'Molybdopterin
BD64_RS18065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_RS18070	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BD64_RS18075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BD64_RS18095	COG2181	nitrate reductase activity
BD64_RS18100	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BD64_RS18105	COG1140	nitrate reductase beta subunit
BD64_RS18110	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BD64_RS18125	COG0714	Associated with various cellular activities
BD64_RS18130	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BD64_RS18135	COG1305	Transglutaminase-like
BD64_RS18140	COG0386	Belongs to the glutathione peroxidase family
BD64_RS18165	COG1595	DNA-templated transcription, initiation
BD64_RS18170	COG0604	alcohol dehydrogenase
BD64_RS18180	COG0346	lactoylglutathione lyase activity
BD64_RS18185	COG1082	Xylose isomerase domain protein TIM barrel
BD64_RS18205	COG2226	methyltransferase
BD64_RS18230	COG3874	Sporulation protein YtfJ
BD64_RS18280	COG0456	acetyltransferase
BD64_RS18305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS18310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS18315	COG1819	glycosyl
BD64_RS18330	COG4106	trans-aconitate 2-methyltransferase activity
BD64_RS18335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BD64_RS18345	COG0561	phosphatase activity
BD64_RS18365	COG2211	Major facilitator Superfamily
BD64_RS18370	COG0154	amidase activity
BD64_RS18380	COG1876	peptidase activity
BD64_RS18390	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_RS18410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_RS18415	COG1114	Component of the transport system for branched-chain amino acids
BD64_RS18430	COG1253	flavin adenine dinucleotide binding
BD64_RS18435	COG2839	Protein conserved in bacteria
BD64_RS18440	COG0702	epimerase
BD64_RS18455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_RS18460	COG1607	acyl-coa hydrolase
BD64_RS18465	COG3689	TIGRFAM TIGR03943 family protein
BD64_RS18470	COG0701	Predicted permease
BD64_RS18480	COG2244	polysaccharide biosynthetic process
BD64_RS18485	COG0586	Pfam SNARE associated Golgi protein
BD64_RS18490	COG1051	belongs to the nudix hydrolase family
BD64_RS18495	COG5337	Spore coat protein CotH
BD64_RS18505	COG0406	alpha-ribazole phosphatase activity
BD64_RS18520	COG4166	transmembrane transport
BD64_RS18530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BD64_RS18540	COG0702	epimerase
BD64_RS18550	COG3443	Belongs to the bacterial solute-binding protein 9 family
BD64_RS18550	COG0803	Belongs to the bacterial solute-binding protein 9 family
BD64_RS18615	COG0456	acetyltransferase
BD64_RS18620	COG0523	cobalamin synthesis protein
BD64_RS18625	COG4989	oxidoreductase activity
BD64_RS18635	COG1231	oxidoreductase activity
BD64_RS18645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BD64_RS18660	COG0783	Belongs to the Dps family
BD64_RS18665	COG3949	Membrane
BD64_RS18685	COG0840	transmembrane signaling receptor activity
BD64_RS18710	COG2814	Major facilitator Superfamily
BD64_RS18715	COG0667	Aldo Keto reductase
BD64_RS18720	COG0640	Transcriptional regulator
BD64_RS18725	COG1404	Belongs to the peptidase S8 family
BD64_RS18730	COG2002	toxin-antitoxin pair type II binding
BD64_RS18770	COG1752	Esterase of the alpha-beta hydrolase superfamily
BD64_RS18780	COG1279	arginine transmembrane transporter activity
BD64_RS18795	COG1082	Xylose isomerase domain protein TIM barrel
BD64_RS18805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BD64_RS18825	COG1247	-acetyltransferase
BD64_RS18830	COG1285	pathogenesis
BD64_RS18845	COG5002	protein histidine kinase activity
BD64_RS18850	COG0745	RESPONSE REGULATOR receiver
BD64_RS18860	COG1316	TRANSCRIPTIONal
BD64_RS18885	COG0460	homoserine dehydrogenase
BD64_RS18920	COG0300	oxidoreductase activity
BD64_RS18930	COG5002	protein histidine kinase activity
BD64_RS18935	COG0745	RESPONSE REGULATOR receiver
BD64_RS18940	COG1132	(ABC) transporter
BD64_RS18945	COG1132	(ABC) transporter
BD64_RS18955	COG1388	LysM domain
BD64_RS18955	COG0791	NLP P60 protein
BD64_RS18970	COG1686	Belongs to the peptidase S11 family
BD64_RS18990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BD64_RS18995	COG4988	ABC transporter
BD64_RS19000	COG1294	oxidase, subunit
BD64_RS19005	COG1271	oxidase subunit
BD64_RS19015	COG1846	Transcriptional regulator
BD64_RS19035	COG0583	DNA-binding transcription factor activity
BD64_RS19055	COG0411	ABC transporter
BD64_RS19065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_RS19070	COG2030	dehydratase
BD64_RS19075	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_RS19090	COG0523	cobalamin synthesis protein
BD64_RS19095	COG1231	oxidoreductase activity
BD64_RS19105	COG0628	permease
BD64_RS19120	COG0778	Nitroreductase
BD64_RS19125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BD64_RS19130	COG1959	2 iron, 2 sulfur cluster binding
BD64_RS19135	COG0583	DNA-binding transcription factor activity
BD64_RS19140	COG0697	spore germination
BD64_RS19150	COG4549	nuclear export factor GLE1
BD64_RS19155	COG2372	response to copper ion
BD64_RS19155	COG1276	copper resistance
BD64_RS19170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BD64_RS19185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BD64_RS19200	COG2132	Multicopper oxidase
BD64_RS19205	COG0006	proline dipeptidase activity
BD64_RS19225	COG4224	UPF0291 protein
BD64_RS19240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BD64_RS19245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS19255	COG2390	Transcriptional regulator
BD64_RS19290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BD64_RS19305	COG1914	H( )-stimulated, divalent metal cation uptake system
BD64_RS19325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD64_RS19330	COG0535	radical SAM domain protein
BD64_RS19355	COG4166	transmembrane transport
BD64_RS19360	COG1073	alpha beta
BD64_RS19380	COG0427	acetyl-CoA hydrolase
BD64_RS19385	COG3279	Response regulator of the LytR AlgR family
BD64_RS19395	COG3384	dioxygenase
BD64_RS19400	COG2814	Major facilitator Superfamily
BD64_RS19425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BD64_RS19435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BD64_RS19440	COG0440	acetolactate synthase activity
BD64_RS19445	COG0028	Belongs to the TPP enzyme family
BD64_RS19450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_RS19460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BD64_RS19475	COG2084	Dehydrogenase
BD64_RS19490	COG2323	membrane
BD64_RS19495	COG5566	PFAM Mor transcription activator
BD64_RS19505	COG0733	neurotransmitter:sodium symporter activity
BD64_RS19510	COG2244	polysaccharide biosynthetic process
BD64_RS19525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD64_RS19530	COG2223	nitrite transmembrane transporter activity
BD64_RS19535	COG4166	transmembrane transport
BD64_RS19545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BD64_RS19555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_RS19570	COG1966	Carbon starvation protein
BD64_RS19585	COG2814	Major facilitator Superfamily
BD64_RS19595	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_RS19600	COG1051	belongs to the nudix hydrolase family
BD64_RS19660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BD64_RS19665	COG0784	Response regulator, receiver
BD64_RS19670	COG4191	Histidine kinase
BD64_RS19675	COG0281	malic enzyme
BD64_RS19680	COG1027	Aspartate ammonia-lyase
BD64_RS19690	COG0528	UMP kinase activity
BD64_RS19695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_RS19710	COG1131	(ABC) transporter
BD64_RS19745	COG2733	membrane
BD64_RS19780	COG0785	Cytochrome C biogenesis protein
BD64_RS19800	COG3340	Belongs to the peptidase S51 family
BD64_RS19830	COG0114	fumarate hydratase activity
BD64_RS19835	COG1757	Na H antiporter
BD64_RS19840	COG0438	transferase activity, transferring glycosyl groups
BD64_RS19840	COG1216	Glycosyl transferase, family 2
BD64_RS19850	COG0701	Predicted permease
BD64_RS19855	COG0523	cobalamin synthesis protein
BD64_RS19860	COG0697	spore germination
BD64_RS19865	COG1802	Transcriptional regulator
BD64_RS19895	COG0367	asparagine synthase
BD64_RS19925	COG0406	alpha-ribazole phosphatase activity
BD64_RS19935	COG1686	Belongs to the peptidase S11 family
BD64_RS19960	COG1234	tRNA 3'-trailer cleavage
BD64_RS19970	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD64_RS19975	COG3842	ATPase activity
BD64_RS19980	COG0583	DNA-binding transcription factor activity
BD64_RS20005	COG2329	Antibiotic biosynthesis monooxygenase
BD64_RS20025	COG1309	transcriptional regulator
BD64_RS20050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD64_RS20055	COG4786	Flagellar basal body rod
BD64_RS20060	COG1419	protein localization to endoplasmic reticulum
BD64_RS20065	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BD64_RS20070	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BD64_RS20080	COG1987	bacterial-type flagellum assembly
BD64_RS20085	COG1338	Plays a role in the flagellum-specific transport system
BD64_RS20095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_RS20095	COG1776	CheC inhibitor of MCP methylation
BD64_RS20110	COG0741	lytic transglycosylase activity
BD64_RS20115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BD64_RS20140	COG0457	Tetratricopeptide repeat
BD64_RS20140	COG0463	Glycosyl transferase, family 2
BD64_RS20170	COG0463	Glycosyl transferase, family 2
BD64_RS20180	COG0784	Response regulator, receiver
BD64_RS20180	COG0835	chemotaxis
BD64_RS20220	COG1157	protein secretion by the type III secretion system
BD64_RS20230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_RS20240	COG1766	The M ring may be actively involved in energy transduction
BD64_RS20250	COG1558	bacterial-type flagellum-dependent cell motility
BD64_RS20255	COG1815	bacterial-type flagellum-dependent cell motility
BD64_RS20280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BD64_RS20285	COG1256	bacterial-type flagellum assembly
BD64_RS20305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BD64_RS20320	COG1776	CheC inhibitor of MCP methylation
BD64_RS20320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BD64_RS20330	COG2201	protein-glutamate methylesterase activity
BD64_RS20335	COG1360	Flagellar Motor Protein
BD64_RS20340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BD64_RS20350	COG1923	regulation of RNA biosynthetic process
BD64_RS20405	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BD64_RS20410	COG2323	membrane
BD64_RS20420	COG4978	Transcriptional regulator
BD64_RS20420	COG0789	Transcriptional regulator
BD64_RS20425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD64_RS20430	COG0475	glutathione-regulated potassium exporter activity
BD64_RS20440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BD64_RS20445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_RS20450	COG3162	membrane
BD64_RS20465	COG1280	lysine exporter protein (LysE YggA)
BD64_RS20505	COG0328	RNA-DNA hybrid ribonuclease activity
BD64_RS20525	COG0454	-acetyltransferase
BD64_RS20540	COG0438	transferase activity, transferring glycosyl groups
BD64_RS20545	COG1215	transferase activity, transferring glycosyl groups
BD64_RS20560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BD64_RS20585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BD64_RS20600	COG0754	glutathionylspermidine amidase activity
BD64_RS20625	COG0456	acetyltransferase
BD64_RS20635	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BD64_RS20640	COG2311	Membrane
BD64_RS20645	COG2233	PERMEase
BD64_RS20655	COG0024	Methionine aminopeptidase
BD64_RS20660	COG3173	Aminoglycoside phosphotransferase
BD64_RS20670	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BD64_RS20675	COG1199	ATP-dependent helicase activity
BD64_RS20685	COG0116	Belongs to the methyltransferase superfamily
BD64_RS20735	COG4499	WXG100 protein secretion system (Wss), protein YukC
BD64_RS20735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_RS20745	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BD64_RS20750	COG3935	DnaD domain protein
BD64_RS20770	COG1199	ATP-dependent helicase activity
BD64_RS20770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BD64_RS20810	COG0438	transferase activity, transferring glycosyl groups
BD64_RS20815	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BD64_RS20830	COG1694	Mazg nucleotide pyrophosphohydrolase
BD64_RS20835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS20845	COG2738	Putative neutral zinc metallopeptidase
BD64_RS20860	COG4347	Protein of unknown function (DUF1405)
BD64_RS20870	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BD64_RS20890	COG0457	Tetratricopeptide repeat
BD64_RS20895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BD64_RS20915	COG0142	geranyltranstransferase activity
BD64_RS20925	COG0142	geranyltranstransferase activity
BD64_RS20940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BD64_RS21010	COG0252	asparaginase activity
BD64_RS21015	COG0492	ferredoxin-NADP+ reductase activity
BD64_RS21035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BD64_RS21040	COG4862	establishment of competence for transformation
BD64_RS21060	COG1266	CAAX protease self-immunity
BD64_RS21065	COG0514	ATP-dependent DNA helicase (RecQ)
BD64_RS21070	COG4955	Helix-turn-helix domain
BD64_RS21075	COG1141	Ferredoxin
BD64_RS21080	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BD64_RS21095	COG2096	Adenosyltransferase
BD64_RS21100	COG5002	protein histidine kinase activity
BD64_RS21105	COG0745	RESPONSE REGULATOR receiver
BD64_RS21110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BD64_RS21115	COG1333	cytochrome c biogenesis protein
BD64_RS21125	COG1187	pseudouridine synthase activity
BD64_RS21130	COG0700	Nucleoside recognition
BD64_RS21135	COG2715	membrane protein required for spore maturation
BD64_RS21140	COG1686	Belongs to the peptidase S11 family
BD64_RS21145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BD64_RS21160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BD64_RS21160	COG0392	lysyltransferase activity
BD64_RS21180	COG5002	protein histidine kinase activity
BD64_RS21185	COG0582	viral genome integration into host DNA
BD64_RS21195	COG1801	Protein of unknown function DUF72
BD64_RS21200	COG3852	Histidine kinase
BD64_RS21215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_RS21220	COG1392	Phosphate transport regulator
BD64_RS21225	COG0306	phosphate transporter
BD64_RS21230	COG0730	response to heat
BD64_RS21250	COG1017	nitric oxide dioxygenase activity
BD64_RS21250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BD64_RS21275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BD64_RS21285	COG1114	Component of the transport system for branched-chain amino acids
BD64_RS21295	COG2197	response regulator
BD64_RS21300	COG4585	Histidine kinase
BD64_RS21305	COG4758	membrane
BD64_RS21320	COG1757	Na H antiporter
BD64_RS21340	COG0733	neurotransmitter:sodium symporter activity
BD64_RS21350	COG1648	precorrin-2 dehydrogenase activity
BD64_RS21370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BD64_RS21375	COG0529	Catalyzes the synthesis of activated sulfate
BD64_RS21395	COG0019	diaminopimelate decarboxylase activity
BD64_RS21405	COG1368	sulfuric ester hydrolase activity
BD64_RS21410	COG1183	phosphatidylcholine synthase activity
BD64_RS21425	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BD64_RS21460	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BD64_RS21485	COG0473	3-isopropylmalate dehydrogenase activity
BD64_RS21495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BD64_RS21500	COG0440	acetolactate synthase activity
BD64_RS21505	COG0028	Belongs to the TPP enzyme family
BD64_RS21510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_RS21540	COG3874	Sporulation protein YtfJ
BD64_RS21545	COG4709	membrane
BD64_RS21550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD64_RS21555	COG1301	dicarboxylic acid transport
BD64_RS21565	COG1846	Transcriptional regulator
BD64_RS21580	COG1968	undecaprenyl-diphosphatase activity
BD64_RS21585	COG0534	Mate efflux family protein
BD64_RS21605	COG3173	Aminoglycoside phosphotransferase
BD64_RS21620	COG0716	FMN binding
BD64_RS21645	COG1696	Membrane protein involved in D-alanine export
BD64_RS21655	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BD64_RS21660	COG2070	2-Nitropropane dioxygenase
BD64_RS21665	COG1619	proteins homologs of microcin C7 resistance protein MccF
BD64_RS21675	COG1335	isochorismatase
BD64_RS21685	COG1522	sequence-specific DNA binding
BD64_RS21700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BD64_RS21705	COG1131	(ABC) transporter
BD64_RS21715	COG1131	(ABC) transporter
BD64_RS21720	COG1725	Transcriptional regulator
BD64_RS21725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BD64_RS21730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BD64_RS21745	COG1780	Probably involved in ribonucleotide reductase function
BD64_RS21780	COG4873	Protein conserved in bacteria
BD64_RS21795	COG0720	synthase
BD64_RS21805	COG5002	protein histidine kinase activity
BD64_RS21815	COG2318	DinB family
BD64_RS21825	COG1846	Transcriptional regulator
BD64_RS21830	COG3852	Histidine kinase
BD64_RS21840	COG2861	carbohydrate metabolic process
BD64_RS21865	COG1349	DNA-binding transcription factor activity
BD64_RS21895	COG1840	ABC-type Fe3 transport system, periplasmic component
BD64_RS21910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD64_RS21915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_RS21920	COG3243	poly(R)-hydroxyalkanoic acid synthase
BD64_RS21925	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS21945	COG2030	dehydratase
BD64_RS21955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD64_RS21960	COG0861	Integral membrane protein TerC family
BD64_RS21965	COG2116	formate transmembrane transporter activity
BD64_RS21975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BD64_RS21995	COG2186	Transcriptional regulator
BD64_RS22000	COG5002	protein histidine kinase activity
BD64_RS22005	COG0745	RESPONSE REGULATOR receiver
BD64_RS22015	COG3835	regulator
BD64_RS22020	COG0277	FAD linked oxidase domain protein
BD64_RS22025	COG0247	lactate metabolic process
BD64_RS22030	COG2340	Cysteine-rich secretory protein family
BD64_RS22040	COG0564	pseudouridine synthase activity
BD64_RS22050	COG2409	Drug exporters of the RND superfamily
BD64_RS22060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BD64_RS22065	COG1177	transmembrane transport
BD64_RS22070	COG1176	ABC-type spermidine putrescine transport system, permease component I
BD64_RS22075	COG3842	ATPase activity
BD64_RS22080	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS22115	COG0681	Belongs to the peptidase S26 family
BD64_RS22120	COG1686	Belongs to the peptidase S11 family
BD64_RS22130	COG2226	methyltransferase
BD64_RS22190	COG1476	TRANSCRIPTIONal
BD64_RS22200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BD64_RS22250	COG5634	Uncharacterized conserved protein (DUF2278)
BD64_RS22255	COG1620	l-lactate permease
BD64_RS22290	COG0512	Glutamine amidotransferase of anthranilate synthase
BD64_RS22290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BD64_RS22305	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_RS22310	COG5492	domain, Protein
BD64_RS22325	COG2382	esterase
BD64_RS22335	COG2153	protein acetylation
BD64_RS22380	COG1091	dTDP-4-dehydrorhamnose reductase activity
BD64_RS22395	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BD64_RS22415	COG0463	Glycosyl transferase, family 2
BD64_RS22415	COG0457	Tetratricopeptide repeat
BD64_RS22435	COG0463	Glycosyl transferase, family 2
BD64_RS22435	COG1216	Glycosyl transferase, family 2
BD64_RS22440	COG0772	Belongs to the SEDS family
BD64_RS22455	COG0564	pseudouridine synthase activity
BD64_RS22465	COG2357	RelA SpoT domain protein
BD64_RS22475	COG4116	CYTH
BD64_RS22480	COG2346	COG2346, Truncated hemoglobins
BD64_RS22485	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BD64_RS22495	COG1164	Oligoendopeptidase f
BD64_RS22505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_RS22510	COG4862	establishment of competence for transformation
BD64_RS22515	COG0861	Integral membrane protein TerC family
BD64_RS22535	COG4166	transmembrane transport
BD64_RS22540	COG0534	Mate efflux family protein
BD64_RS22545	COG4608	Belongs to the ABC transporter superfamily
BD64_RS22550	COG0444	Belongs to the ABC transporter superfamily
BD64_RS22555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_RS22560	COG0601	transmembrane transport
BD64_RS22565	COG4166	transmembrane transport
BD64_RS22575	COG0180	Tryptophanyl-tRNA synthetase
BD64_RS22585	COG5504	Zn-dependent protease
BD64_RS22590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BD64_RS22595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD64_RS22610	COG2267	carboxylic ester hydrolase activity
BD64_RS22620	COG0542	response to heat
BD64_RS22635	COG0561	phosphatase activity
BD64_RS22650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS22660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BD64_RS22670	COG2996	Protein conserved in bacteria
BD64_RS22695	COG0004	ammonium transporteR
BD64_RS22700	COG0753	catalase activity
BD64_RS22705	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BD64_RS22710	COG0367	asparagine synthase
BD64_RS22735	COG0179	Fumarylacetoacetate (FAA) hydrolase
BD64_RS22780	COG1074	ATP-dependent DNA helicase activity
BD64_RS22785	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BD64_RS22795	COG0398	Pfam SNARE associated Golgi protein
BD64_RS22800	COG4903	ComK protein
BD64_RS22825	COG2224	Isocitrate lyase
BD64_RS22830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BD64_RS22850	COG0697	spore germination
BD64_RS22855	COG0840	transmembrane signaling receptor activity
BD64_RS22860	COG0501	Belongs to the peptidase M48B family
BD64_RS22885	COG0745	RESPONSE REGULATOR receiver
BD64_RS22890	COG2205	protein histidine kinase activity
BD64_RS22905	COG2207	Transcriptional regulator
BD64_RS22905	COG3708	Transcriptional regulator
BD64_RS22910	COG1595	DNA-templated transcription, initiation
BD64_RS22920	COG1078	dGTPase activity
BD64_RS22925	COG1408	metallophosphoesterase
BD64_RS22970	COG3209	COG3209 Rhs family protein
BD64_RS23000	COG0318	PFAM AMP-dependent synthetase and ligase
BD64_RS23010	COG0095	Lipoate-protein ligase
BD64_RS23015	COG1234	tRNA 3'-trailer cleavage
BD64_RS23025	COG1609	Transcriptional regulator
BD64_RS23050	COG1511	domain protein
BD64_RS23055	COG1309	transcriptional regulator
BD64_RS23090	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BD64_RS23095	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BD64_RS23100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BD64_RS23105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BD64_RS23110	COG2329	Antibiotic biosynthesis monooxygenase
BD64_RS23115	COG3428	Bacterial PH domain
BD64_RS23120	COG3402	PFAM membrane-flanked domain
BD64_RS23165	COG3428	Bacterial PH domain
BD64_RS23175	COG3402	PFAM membrane-flanked domain
BD64_RS23185	COG1309	transcriptional regulator
BD64_RS23195	COG4473	ABC transporter
BD64_RS23200	COG1131	(ABC) transporter
BD64_RS23205	COG0537	adenosine 5'-monophosphoramidase activity
BD64_RS23210	COG4980	gas vesicle protein
BD64_RS23235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BD64_RS23240	COG3973	AAA domain
BD64_RS23250	COG0477	Major facilitator Superfamily
BD64_RS23255	COG0477	Major facilitator Superfamily
BD64_RS23295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BD64_RS23305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BD64_RS23310	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BD64_RS23330	COG2267	carboxylic ester hydrolase activity
BD64_RS23335	COG0457	Tetratricopeptide repeat
BD64_RS23340	COG0346	lactoylglutathione lyase activity
BD64_RS23345	COG0346	lactoylglutathione lyase activity
BD64_RS23350	COG2814	Major facilitator Superfamily
BD64_RS23355	COG1309	transcriptional regulator
BD64_RS23375	COG4717	serine-type aminopeptidase activity
BD64_RS23380	COG0420	3'-5' exonuclease activity
BD64_RS23440	COG2198	Histidine kinase
BD64_RS23440	COG2205	protein histidine kinase activity
BD64_RS23440	COG0784	Response regulator, receiver
BD64_RS23440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_RS23445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BD64_RS23450	COG2208	phosphoserine phosphatase activity
BD64_RS23460	COG1191	sigma factor activity
BD64_RS23485	COG3237	CsbD-like
BD64_RS23535	COG3437	response regulator, receiver
BD64_RS23535	COG2770	Histidine kinase
BD64_RS23560	COG1959	2 iron, 2 sulfur cluster binding
BD64_RS23565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BD64_RS23580	COG2376	Dihydroxyacetone kinase
BD64_RS23600	COG1183	phosphatidylcholine synthase activity
BD64_RS23620	COG1309	transcriptional regulator
BD64_RS23625	COG3320	Male sterility
BD64_RS23625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BD64_RS23675	COG0477	Major facilitator Superfamily
BD64_RS23715	COG0305	Participates in initiation and elongation during chromosome replication
BD64_RS23730	COG4978	Transcriptional regulator
BD64_RS23730	COG0789	Transcriptional regulator
BD64_RS23760	COG3181	Tripartite tricarboxylate transporter family receptor
BD64_RS23765	COG4565	transcriptional regulatory protein
BD64_RS23770	COG3290	protein histidine kinase activity
BD64_RS23775	COG0477	Major facilitator Superfamily
BD64_RS23805	COG4608	Belongs to the ABC transporter superfamily
BD64_RS23815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_RS23820	COG0601	transmembrane transport
BD64_RS23860	COG3938	Belongs to the proline racemase family
BD64_RS23880	COG1363	Peptidase, m42
BD64_RS23900	COG1024	Enoyl-CoA hydratase
BD64_RS23915	COG1696	Membrane protein involved in D-alanine export
BD64_RS23930	COG4196	transglutaminase domain protein
BD64_RS23935	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_RS23945	COG2244	polysaccharide biosynthetic process
BD64_RS23950	COG0653	protein targeting
BD64_RS23970	COG0659	secondary active sulfate transmembrane transporter activity
BD64_RS23985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BD64_RS24000	COG0561	phosphatase activity
BD64_RS24015	COG3527	Alpha-acetolactate decarboxylase
BD64_RS24020	COG0028	Belongs to the TPP enzyme family
BD64_RS24050	COG0189	ligase activity
BD64_RS24065	COG1126	abc transporter atp-binding protein
BD64_RS24070	COG0765	amino acid transport
BD64_RS24075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_RS24085	COG1132	(ABC) transporter
BD64_RS24095	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS24105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BD64_RS24110	COG0531	amino acid
BD64_RS24120	COG0693	protein deglycase activity
BD64_RS24120	COG0753	catalase activity
BD64_RS24125	COG0693	protein deglycase activity
BD64_RS24135	COG2211	Major facilitator Superfamily
BD64_RS24140	COG4533	DNA binding
BD64_RS24145	COG2249	NAD(P)H dehydrogenase (quinone) activity
BD64_RS24155	COG1733	regulation of RNA biosynthetic process
BD64_RS24160	COG2814	Major facilitator Superfamily
BD64_RS24165	COG1309	transcriptional regulator
BD64_RS24170	COG2076	Multidrug Resistance protein
BD64_RS24185	COG1522	sequence-specific DNA binding
BD64_RS24190	COG0697	spore germination
BD64_RS24205	COG2259	Doxx family
BD64_RS24215	COG1263	PTS System
BD64_RS24215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_RS24225	COG1737	Transcriptional regulator
BD64_RS24235	COG0475	glutathione-regulated potassium exporter activity
BD64_RS24240	COG0531	amino acid
BD64_RS24275	COG0586	Pfam SNARE associated Golgi protein
BD64_RS24310	COG3546	catalase activity
BD64_RS24315	COG1114	Component of the transport system for branched-chain amino acids
BD64_RS24330	COG5522	Integral membrane protein (intg_mem_TP0381)
BD64_RS24340	COG1136	(ABC) transporter
BD64_RS24345	COG0577	efflux transmembrane transporter activity
BD64_RS24350	COG1388	LysM domain
BD64_RS24350	COG3584	3D domain protein
BD64_RS24370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BD64_RS24375	COG1447	Phosphotransferase system cellobiose-specific component IIA
BD64_RS24380	COG3711	transcriptional antiterminator
BD64_RS24380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BD64_RS24395	COG1283	sodium-dependent phosphate transmembrane transporter activity
BD64_RS24400	COG0604	alcohol dehydrogenase
BD64_RS24405	COG1316	TRANSCRIPTIONal
BD64_RS24415	COG0730	response to heat
BD64_RS24420	COG2210	Belongs to the sulfur carrier protein TusA family
BD64_RS24430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_RS24435	COG0425	Belongs to the sulfur carrier protein TusA family
BD64_RS24440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD64_RS24440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_RS24445	COG0425	Belongs to the sulfur carrier protein TusA family
BD64_RS24445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD64_RS24450	COG1937	Protein conserved in bacteria
BD64_RS24455	COG0446	pyridine nucleotide-disulphide oxidoreductase
BD64_RS24480	COG2719	SpoVR family
BD64_RS24485	COG0778	Nitroreductase
BD64_RS24525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BD64_RS24530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BD64_RS24540	COG1609	Transcriptional regulator
BD64_RS24545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_RS24545	COG1263	PTS System
BD64_RS24550	COG1621	beta-fructofuranosidase activity
BD64_RS24555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BD64_RS24570	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS24575	COG2252	PERMEase
BD64_RS24590	COG1846	Transcriptional regulator
BD64_RS24595	COG2814	Major facilitator Superfamily
BD64_RS24600	COG2205	protein histidine kinase activity
BD64_RS24645	COG0351	phosphomethylpyrimidine kinase
BD64_RS24650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD64_RS24660	COG2104	thiamine diphosphate biosynthetic process
BD64_RS24665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_RS24670	COG0352	thiamine-phosphate diphosphorylase activity
BD64_RS24675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BD64_RS24680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_RS24685	COG1116	anion transmembrane transporter activity
BD64_RS24690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BD64_RS24715	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BD64_RS24835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BD64_RS24845	COG0581	inorganic phosphate transmembrane transporter activity
BD64_RS24850	COG0573	inorganic phosphate transmembrane transporter activity
BD64_RS24855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BD64_RS24860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD64_RS24860	COG1918	ferrous iron import across plasma membrane
BD64_RS24865	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD64_RS24870	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD64_RS24885	COG0531	amino acid
BD64_RS24890	COG0697	spore germination
BD64_RS24895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD64_RS24910	COG4990	cell redox homeostasis
BD64_RS24915	COG0833	amino acid
BD64_RS24920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BD64_RS24925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BD64_RS24940	COG0569	domain protein
BD64_RS24940	COG0475	glutathione-regulated potassium exporter activity
BD64_RS24965	COG2252	PERMEase
BD64_RS24970	COG1113	amino acid transport
BD64_RS24985	COG1114	Component of the transport system for branched-chain amino acids
BD64_RS24990	COG3104	oligopeptide transport
BD64_RS25005	COG1476	TRANSCRIPTIONal
BD64_RS25010	COG1388	LysM domain
BD64_RS25010	COG3584	3D domain protein
BD64_RS25015	COG0840	transmembrane signaling receptor activity
BD64_RS25020	COG1968	undecaprenyl-diphosphatase activity
BD64_RS25045	COG3568	Endonuclease Exonuclease Phosphatase
BD64_RS25060	COG1063	alcohol dehydrogenase
BD64_RS25085	COG1879	ABC-type sugar transport system periplasmic component
BD64_RS25090	COG1172	Belongs to the binding-protein-dependent transport system permease family
BD64_RS25105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BD64_RS25110	COG1609	Transcriptional regulator
BD64_RS25115	COG0477	Major facilitator Superfamily
BD64_RS25120	COG0477	Major facilitator Superfamily
BD64_RS25125	COG1846	Transcriptional regulator
BD64_RS25130	COG2271	Major facilitator Superfamily
BD64_RS25140	COG4608	Belongs to the ABC transporter superfamily
BD64_RS25145	COG0601	transmembrane transport
BD64_RS25155	COG0747	negative chemotaxis
BD64_RS25170	COG0659	secondary active sulfate transmembrane transporter activity
BD64_RS25185	COG5002	protein histidine kinase activity
BD64_RS25190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BD64_RS25195	COG2378	regulation of single-species biofilm formation
BD64_RS25220	COG0833	amino acid
BD64_RS25225	COG0765	amino acid transport
BD64_RS25230	COG0765	amino acid transport
BD64_RS25235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_RS25240	COG1126	abc transporter atp-binding protein
BD64_RS25245	COG1115	amino acid carrier protein
BD64_RS25250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BD64_RS25260	COG0697	spore germination
BD64_RS25275	COG0366	Alpha amylase catalytic
BD64_RS25280	COG1263	PTS System
BD64_RS25280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_RS25285	COG2188	Transcriptional regulator
BD64_RS25290	COG0531	amino acid
BD64_RS25310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BD64_RS25315	COG0714	Associated with various cellular activities
BD64_RS25320	COG4548	von Willebrand factor, type A
BD64_RS25330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD64_RS25335	COG0156	8-amino-7-oxononanoate synthase activity
BD64_RS25340	COG2226	methyltransferase
BD64_RS25350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS25355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS25360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS25365	COG3104	oligopeptide transport
BD64_RS25380	COG1620	l-lactate permease
BD64_RS25385	COG1027	Aspartate ammonia-lyase
BD64_RS25390	COG1253	flavin adenine dinucleotide binding
BD64_RS25395	COG0346	lactoylglutathione lyase activity
BD64_RS25400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS25405	COG1316	TRANSCRIPTIONal
BD64_RS25410	COG2720	vancomycin resistance protein
BD64_RS25430	COG3227	Zinc metalloprotease (Elastase)
BD64_RS25440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BD64_RS25445	COG2217	Heavy metal translocating P-type atpase
BD64_RS25450	COG0640	Transcriptional regulator
BD64_RS25455	COG0531	amino acid
BD64_RS25470	COG2427	Protein of unknown function (DUF1641)
BD64_RS25475	COG3383	formate dehydrogenase (NAD+) activity
BD64_RS25480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BD64_RS25485	COG0454	-acetyltransferase
BD64_RS25485	COG0456	acetyltransferase
BD64_RS25495	COG0745	RESPONSE REGULATOR receiver
BD64_RS25500	COG5002	protein histidine kinase activity
BD64_RS25510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD64_RS25525	COG0281	malic enzyme
BD64_RS25530	COG3493	citrate carrier protein
BD64_RS25535	COG4565	transcriptional regulatory protein
BD64_RS25540	COG3290	protein histidine kinase activity
BD64_RS25550	COG4990	cell redox homeostasis
BD64_RS25560	COG5002	protein histidine kinase activity
BD64_RS25565	COG0745	RESPONSE REGULATOR receiver
BD64_RS25570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BD64_RS25580	COG0395	ABC-type sugar transport system, permease component
BD64_RS25585	COG1175	transmembrane transport
BD64_RS25590	COG3842	ATPase activity
BD64_RS25595	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BD64_RS25615	COG2851	Citrate transporter
BD64_RS25620	COG4565	transcriptional regulatory protein
BD64_RS25625	COG3290	protein histidine kinase activity
BD64_RS25635	COG2268	Band 7 protein
BD64_RS25640	COG1585	Membrane protein implicated in regulation of membrane protease activity
BD64_RS25650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BD64_RS25675	COG2766	serine protein kinase
BD64_RS25690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BD64_RS25700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BD64_RS25710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BD64_RS25715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BD64_RS25830	COG0735	belongs to the Fur family
BD64_RS25835	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BD64_RS25855	COG4555	ABC transporter
BD64_RS25865	COG0067	glutamate synthase
BD64_RS25865	COG0069	glutamate synthase activity
BD64_RS25865	COG0070	glutamate synthase
BD64_RS25870	COG4129	membrane
BD64_RS25875	COG1132	(ABC) transporter
BD64_RS25900	COG1194	a g-specific adenine glycosylase
BD64_RS25905	COG1988	membrane-bound metal-dependent
BD64_RS25935	COG1090	epimerase
BD64_RS25940	COG1228	amidohydrolase
BD64_RS25960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BD64_RS25980	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BD64_RS25980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD64_RS25995	COG0463	Glycosyl transferase, family 2
BD64_RS26010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BD64_RS26015	COG1263	PTS System
BD64_RS26015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_RS26050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD64_RS26055	COG0833	amino acid
BD64_RS26065	COG3829	transcription factor binding
BD64_RS26075	COG0101	tRNA pseudouridine synthase activity
BD64_RS26200	COG0582	viral genome integration into host DNA
BD64_RS26205	COG0582	viral genome integration into host DNA
BD64_RS26300	COG1484	DNA-dependent DNA replication
BD64_RS26335	COG1396	sequence-specific DNA binding
BD64_RS26350	COG1396	sequence-specific DNA binding
BD64_RS26355	COG0582	viral genome integration into host DNA
BD64_RS26360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD64_RS26365	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BD64_RS26390	COG0535	radical SAM domain protein
BD64_RS26400	COG0387	Pfam Sodium calcium exchanger
BD64_RS26405	COG3871	stress protein (general stress protein 26)
BD64_RS26420	COG0586	Pfam SNARE associated Golgi protein
BD64_RS26440	COG0697	spore germination
BD64_RS26445	COG2217	Heavy metal translocating P-type atpase
BD64_RS26450	COG1295	ribonuclease BN
BD64_RS26460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BD64_RS26475	COG3853	Toxic anion resistance protein (TelA)
BD64_RS26485	COG0861	Integral membrane protein TerC family
BD64_RS26490	COG2310	stress, protein
BD64_RS26495	COG2310	stress, protein
BD64_RS26500	COG2310	stress, protein
BD64_RS26515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD64_RS26530	COG2270	Major facilitator Superfamily
BD64_RS26575	COG0488	(ABC) transporter
BD64_RS26580	COG1116	anion transmembrane transporter activity
BD64_RS26590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BD64_RS26605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BD64_RS26635	COG2190	(PTS) system
BD64_RS26635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BD64_RS26635	COG1263	PTS System
BD64_RS26640	COG0366	Alpha amylase catalytic
BD64_RS26645	COG0840	transmembrane signaling receptor activity
BD64_RS26650	COG0840	transmembrane signaling receptor activity
BD64_RS26660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BD64_RS26665	COG0765	amino acid transport
BD64_RS26675	COG0723	plastoquinol--plastocyanin reductase activity
BD64_RS26675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD64_RS26680	COG2814	Major facilitator Superfamily
BD64_RS26685	COG3541	Predicted nucleotidyltransferase
BD64_RS26705	COG5002	protein histidine kinase activity
BD64_RS26740	COG0166	Belongs to the GPI family
BD64_RS26760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD64_RS26765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS26770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD64_RS26790	COG0450	alkyl hydroperoxide reductase
BD64_RS26805	COG1473	amidohydrolase
BD64_RS26810	COG1757	Na H antiporter
BD64_RS26835	COG4807	Protein conserved in bacteria
BD64_RS26845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BD64_RS26850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD64_RS26855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BD64_RS26870	COG2309	aminopeptidase activity
BD64_RS26875	COG2076	Multidrug Resistance protein
BD64_RS26880	COG1012	belongs to the aldehyde dehydrogenase family
BD64_RS26890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BD64_RS26895	COG0546	phosphoglycolate phosphatase activity
BD64_RS26900	COG1597	lipid kinase activity
BD64_RS26925	COG1846	Transcriptional regulator
BD64_RS26945	COG1464	Belongs to the NlpA lipoprotein family
BD64_RS26950	COG2011	ABC-type metal ion transport system permease component
BD64_RS26955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD64_RS26960	COG1335	isochorismatase
BD64_RS26980	COG4851	CamS sex pheromone cAM373 precursor
BD64_RS26990	COG0210	DNA helicase
BD64_RS27015	COG0151	Belongs to the GarS family
BD64_RS27025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BD64_RS27035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BD64_RS27050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BD64_RS27060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BD64_RS27065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BD64_RS27070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BD64_RS27125	COG2226	methyltransferase
BD64_RS27155	COG5002	protein histidine kinase activity
BD64_RS27165	COG2252	PERMEase
BD64_RS27185	COG1266	CAAX protease self-immunity
BD64_RS27200	COG0488	(ABC) transporter
BD64_RS27210	COG0456	acetyltransferase
BD64_RS27215	COG1214	PFAM Peptidase M22, glycoprotease
BD64_RS27220	COG0802	atpase or kinase
BD64_RS27315	COG2183	response to ionizing radiation
BD64_RS27320	COG2337	Toxic component of a toxin-antitoxin (TA) module
BD64_RS27325	COG0864	Transcriptional regulator
BD64_RS27330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BD64_RS27335	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BD64_RS27345	COG0705	Rhomboid family
BD64_RS27345	COG0457	Tetratricopeptide repeat
BD64_RS27350	COG4294	response to UV
BD64_RS27360	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BD64_RS27375	COG2814	Major facilitator Superfamily
BD64_RS27385	COG0179	Fumarylacetoacetate (FAA) hydrolase
BD64_RS27390	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BD64_RS27430	COG4608	Belongs to the ABC transporter superfamily
BD64_RS27435	COG0444	Belongs to the ABC transporter superfamily
BD64_RS27440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_RS27445	COG0601	transmembrane transport
BD64_RS27450	COG0747	negative chemotaxis
BD64_RS27465	COG0488	(ABC) transporter
BD64_RS27490	COG5298	Protein conserved in bacteria
BD64_RS27495	COG0084	hydrolase, TatD family'
BD64_RS27510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BD64_RS27520	COG1609	Transcriptional regulator
BD64_RS27530	COG0204	Acyl-transferase
BD64_RS27540	COG0697	spore germination
BD64_RS27545	COG0583	DNA-binding transcription factor activity
BD64_RS27560	COG1910	domain protein
BD64_RS27565	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD64_RS27570	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD64_RS27575	COG4149	molybdate abc transporter
BD64_RS27595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BD64_RS27600	COG0656	L-ascorbic acid biosynthetic process
BD64_RS27605	COG4166	transmembrane transport
BD64_RS27610	COG4166	transmembrane transport
BD64_RS27625	COG2207	Transcriptional regulator
BD64_RS27635	COG4166	transmembrane transport
BD64_RS27640	COG4608	Belongs to the ABC transporter superfamily
BD64_RS27645	COG0444	Belongs to the ABC transporter superfamily
BD64_RS27650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD64_RS27655	COG0601	transmembrane transport
BD64_RS27670	COG2814	Major facilitator Superfamily
BD64_RS27680	COG2271	Major facilitator Superfamily
BD64_RS27685	COG0277	FAD linked oxidase domain protein
BD64_RS27695	COG0604	alcohol dehydrogenase
BD64_RS27700	COG1464	Belongs to the NlpA lipoprotein family
BD64_RS27705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD64_RS27710	COG2011	ABC-type metal ion transport system permease component
BD64_RS27715	COG1028	Short-chain dehydrogenase reductase Sdr
BD64_RS27750	COG1506	peptidase
BD64_RS27750	COG4946	Tricorn protease homolog
BD64_RS27750	COG0823	Involved in the tonB-independent uptake of proteins
BD64_RS27755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BD64_RS27775	COG0596	Alpha beta hydrolase
BD64_RS27780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BD64_RS27795	COG4856	YbbR-like protein
BD64_RS27800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BD64_RS27885	COG0726	polysaccharide deacetylase
BD64_RS27890	COG2194	sulfuric ester hydrolase activity
BD64_RS27900	COG0489	protein tyrosine kinase activity
BD64_RS27905	COG0860	N-Acetylmuramoyl-L-alanine amidase
BD64_RS27930	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BD64_RS27965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BD64_RS27975	COG0024	Methionine aminopeptidase
BD64_RS27985	COG0201	protein transport
BD64_RS28045	COG0255	Belongs to the universal ribosomal protein uL29 family
BD64_RS28115	COG1358	cellular component organization or biogenesis
BD64_RS28120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BD64_RS28130	COG2813	Specifically methylates the guanine in position
BD64_RS28150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BD64_RS28155	COG0250	Participates in transcription elongation, termination and antitermination
BD64_RS28160	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BD64_RS28175	COG3688	RNA-binding protein containing a PIN domain
BD64_RS28180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BD64_RS28195	COG1045	serine acetyltransferase
BD64_RS28215	COG4956	integral membrane protein (PIN domain superfamily)
BD64_RS28225	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BD64_RS28230	COG0542	response to heat
BD64_RS28240	COG3880	PFAM UvrB UvrC protein
BD64_RS28270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BD64_RS28275	COG1396	sequence-specific DNA binding
BD64_RS28280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BD64_RS28285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BD64_RS28290	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BD64_RS28295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BD64_RS28300	COG0512	Glutamine amidotransferase of anthranilate synthase
BD64_RS28305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BD64_RS28310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD64_RS28325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD64_RS28330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BD64_RS28335	COG0037	tRNA processing
BD64_RS28340	COG2208	phosphoserine phosphatase activity
BD64_RS28355	COG1098	S1 RNA binding domain
BD64_RS28375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BD64_RS28380	COG3956	TIGRFAM MazG family protein
BD64_RS28385	COG2244	polysaccharide biosynthetic process
BD64_RS28390	COG2002	toxin-antitoxin pair type II binding
BD64_RS28395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BD64_RS28425	COG0251	oxidation-reduction process
BD64_RS28430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BD64_RS28445	COG4466	Protein conserved in bacteria
BD64_RS28460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BD64_RS28465	COG0084	hydrolase, TatD family'
BD64_RS28470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_RS28470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD64_RS28475	COG2002	toxin-antitoxin pair type II binding
BD64_RS28480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BD64_RS28490	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BD64_RS28500	COG1774	PSP1 C-terminal conserved region
BD64_RS28505	COG0470	DNA polymerase III
BD64_RS28515	COG1982	Orn Lys Arg decarboxylase major
BD64_RS28570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BD64_RS28575	COG0590	tRNA wobble adenosine to inosine editing
BD64_RS28585	COG1335	isochorismatase
BD64_RS28590	COG1428	Deoxynucleoside kinase
BD64_RS28595	COG1428	Deoxynucleoside kinase
BD64_RS28625	COG1686	Belongs to the peptidase S11 family
BD64_RS28630	COG0517	IMP dehydrogenase activity
BD64_RS28630	COG0516	GMP reductase activity
BD64_RS28665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BD64_RS28670	COG0187	DNA topoisomerase II activity
BD64_RS28680	COG2501	S4 domain
BD64_RS28685	COG0592	DNA-directed DNA polymerase activity
BD64_RS28695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BD64_RS28705	COG0706	membrane insertase activity
BD64_RS28710	COG1847	R3H domain protein
BD64_RS28735	COG1192	Involved in chromosome partitioning
BD64_RS28740	COG1475	DNA binding
BD64_RS28750	COG0668	transmembrane transport
BD64_RS28755	COG4481	Protein conserved in bacteria
BD64_RS28760	COG0012	GTP binding
BD64_RS28770	COG0629	single-stranded DNA binding
BD64_RS28780	COG4241	membrane
BD64_RS28785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BD64_RS28835	COG2376	Dihydroxyacetone kinase