locus-tag	class	description
AOD63_RS00010	COG0592	DNA-directed DNA polymerase activity
AOD63_RS00015	COG2501	S4 domain
AOD63_RS00025	COG0187	DNA topoisomerase II activity
AOD63_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOD63_RS00065	COG0516	GMP reductase activity
AOD63_RS00065	COG0517	IMP dehydrogenase activity
AOD63_RS00070	COG1686	Belongs to the peptidase S11 family
AOD63_RS00100	COG1428	Deoxynucleoside kinase
AOD63_RS00105	COG1428	Deoxynucleoside kinase
AOD63_RS00110	COG1335	isochorismatase
AOD63_RS00120	COG0590	tRNA wobble adenosine to inosine editing
AOD63_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOD63_RS00185	COG1982	Orn Lys Arg decarboxylase major
AOD63_RS00195	COG0470	DNA polymerase III
AOD63_RS00200	COG1774	PSP1 C-terminal conserved region
AOD63_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AOD63_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOD63_RS00225	COG2002	toxin-antitoxin pair type II binding
AOD63_RS00230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD63_RS00230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD63_RS00235	COG0084	hydrolase, TatD family'
AOD63_RS00240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AOD63_RS00255	COG4466	Protein conserved in bacteria
AOD63_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOD63_RS00275	COG0251	oxidation-reduction process
AOD63_RS00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOD63_RS00310	COG2002	toxin-antitoxin pair type II binding
AOD63_RS00315	COG2244	polysaccharide biosynthetic process
AOD63_RS00320	COG3956	TIGRFAM MazG family protein
AOD63_RS00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOD63_RS00345	COG1098	S1 RNA binding domain
AOD63_RS00360	COG2208	phosphoserine phosphatase activity
AOD63_RS00365	COG0037	tRNA processing
AOD63_RS00370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AOD63_RS00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOD63_RS00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOD63_RS00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOD63_RS00400	COG0512	Glutamine amidotransferase of anthranilate synthase
AOD63_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD63_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOD63_RS00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOD63_RS00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOD63_RS00425	COG1396	sequence-specific DNA binding
AOD63_RS00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOD63_RS00460	COG3880	PFAM UvrB UvrC protein
AOD63_RS00470	COG0542	response to heat
AOD63_RS00475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOD63_RS00485	COG4956	integral membrane protein (PIN domain superfamily)
AOD63_RS00505	COG1045	serine acetyltransferase
AOD63_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOD63_RS00525	COG3688	RNA-binding protein containing a PIN domain
AOD63_RS00540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOD63_RS00545	COG0250	Participates in transcription elongation, termination and antitermination
AOD63_RS00550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOD63_RS00570	COG2813	Specifically methylates the guanine in position
AOD63_RS00580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOD63_RS00585	COG1358	cellular component organization or biogenesis
AOD63_RS00655	COG0255	Belongs to the universal ribosomal protein uL29 family
AOD63_RS00715	COG0201	protein transport
AOD63_RS00725	COG0024	Methionine aminopeptidase
AOD63_RS00735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOD63_RS00770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOD63_RS00795	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS00800	COG0489	protein tyrosine kinase activity
AOD63_RS00810	COG2194	sulfuric ester hydrolase activity
AOD63_RS00815	COG0726	polysaccharide deacetylase
AOD63_RS00900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AOD63_RS00905	COG4856	YbbR-like protein
AOD63_RS00920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOD63_RS00925	COG0596	Alpha beta hydrolase
AOD63_RS00945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOD63_RS00950	COG0823	Involved in the tonB-independent uptake of proteins
AOD63_RS00950	COG1506	peptidase
AOD63_RS00950	COG4946	Tricorn protease homolog
AOD63_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS00990	COG2011	ABC-type metal ion transport system permease component
AOD63_RS00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOD63_RS01000	COG1464	Belongs to the NlpA lipoprotein family
AOD63_RS01005	COG0604	alcohol dehydrogenase
AOD63_RS01015	COG0277	FAD linked oxidase domain protein
AOD63_RS01020	COG2271	Major facilitator Superfamily
AOD63_RS01030	COG2814	Major facilitator Superfamily
AOD63_RS01045	COG0601	transmembrane transport
AOD63_RS01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD63_RS01055	COG0444	Belongs to the ABC transporter superfamily
AOD63_RS01060	COG4608	Belongs to the ABC transporter superfamily
AOD63_RS01065	COG4166	transmembrane transport
AOD63_RS01075	COG2207	Transcriptional regulator
AOD63_RS01090	COG4166	transmembrane transport
AOD63_RS01095	COG4166	transmembrane transport
AOD63_RS01100	COG0656	L-ascorbic acid biosynthetic process
AOD63_RS01105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD63_RS01125	COG4149	molybdate abc transporter
AOD63_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOD63_RS01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOD63_RS01140	COG1910	domain protein
AOD63_RS01155	COG0583	DNA-binding transcription factor activity
AOD63_RS01160	COG0697	spore germination
AOD63_RS01175	COG0204	Acyl-transferase
AOD63_RS01190	COG1609	Transcriptional regulator
AOD63_RS01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS01215	COG0084	hydrolase, TatD family'
AOD63_RS01220	COG5298	Protein conserved in bacteria
AOD63_RS01245	COG0488	(ABC) transporter
AOD63_RS01255	COG0747	negative chemotaxis
AOD63_RS01260	COG0601	transmembrane transport
AOD63_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD63_RS01270	COG0444	Belongs to the ABC transporter superfamily
AOD63_RS01275	COG4608	Belongs to the ABC transporter superfamily
AOD63_RS01300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AOD63_RS01305	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOD63_RS01315	COG2814	Major facilitator Superfamily
AOD63_RS01330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOD63_RS01340	COG4294	response to UV
AOD63_RS01345	COG0705	Rhomboid family
AOD63_RS01345	COG0457	Tetratricopeptide repeat
AOD63_RS01355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOD63_RS01360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOD63_RS01365	COG0864	Transcriptional regulator
AOD63_RS01370	COG2337	Toxic component of a toxin-antitoxin (TA) module
AOD63_RS01375	COG2183	response to ionizing radiation
AOD63_RS01470	COG0802	atpase or kinase
AOD63_RS01475	COG1214	PFAM Peptidase M22, glycoprotease
AOD63_RS01480	COG0456	acetyltransferase
AOD63_RS01490	COG0488	(ABC) transporter
AOD63_RS01505	COG1266	CAAX protease self-immunity
AOD63_RS01525	COG2252	PERMEase
AOD63_RS01535	COG5002	protein histidine kinase activity
AOD63_RS01565	COG2226	methyltransferase
AOD63_RS01605	COG1968	undecaprenyl-diphosphatase activity
AOD63_RS01620	COG2205	protein histidine kinase activity
AOD63_RS01625	COG0745	RESPONSE REGULATOR receiver
AOD63_RS01645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOD63_RS01650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOD63_RS01655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOD63_RS01665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOD63_RS01680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOD63_RS01690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOD63_RS01700	COG0151	Belongs to the GarS family
AOD63_RS01725	COG0210	DNA helicase
AOD63_RS01735	COG4851	CamS sex pheromone cAM373 precursor
AOD63_RS01755	COG1335	isochorismatase
AOD63_RS01760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOD63_RS01765	COG2011	ABC-type metal ion transport system permease component
AOD63_RS01770	COG1464	Belongs to the NlpA lipoprotein family
AOD63_RS01790	COG1846	Transcriptional regulator
AOD63_RS01815	COG1597	lipid kinase activity
AOD63_RS01820	COG0546	phosphoglycolate phosphatase activity
AOD63_RS01825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOD63_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS01840	COG2076	Multidrug Resistance protein
AOD63_RS01845	COG2309	aminopeptidase activity
AOD63_RS01860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS01865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOD63_RS01870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOD63_RS01880	COG4807	Protein conserved in bacteria
AOD63_RS01905	COG1757	Na H antiporter
AOD63_RS01910	COG1473	amidohydrolase
AOD63_RS01925	COG0450	alkyl hydroperoxide reductase
AOD63_RS01945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS01950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS01955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS01975	COG0166	Belongs to the GPI family
AOD63_RS02010	COG5002	protein histidine kinase activity
AOD63_RS02030	COG3541	Predicted nucleotidyltransferase
AOD63_RS02035	COG2814	Major facilitator Superfamily
AOD63_RS02040	COG0723	plastoquinol--plastocyanin reductase activity
AOD63_RS02040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD63_RS02050	COG0765	amino acid transport
AOD63_RS02055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD63_RS02070	COG0840	transmembrane signaling receptor activity
AOD63_RS02075	COG0840	transmembrane signaling receptor activity
AOD63_RS02080	COG0366	Alpha amylase catalytic
AOD63_RS02085	COG2190	(PTS) system
AOD63_RS02085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD63_RS02085	COG1263	PTS System
AOD63_RS02115	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AOD63_RS02130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD63_RS02140	COG1116	anion transmembrane transporter activity
AOD63_RS02145	COG0488	(ABC) transporter
AOD63_RS02190	COG2270	Major facilitator Superfamily
AOD63_RS02205	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOD63_RS02220	COG2310	stress, protein
AOD63_RS02225	COG2310	stress, protein
AOD63_RS02230	COG2310	stress, protein
AOD63_RS02235	COG0861	Integral membrane protein TerC family
AOD63_RS02245	COG3853	Toxic anion resistance protein (TelA)
AOD63_RS02260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOD63_RS02270	COG1295	ribonuclease BN
AOD63_RS02275	COG2217	Heavy metal translocating P-type atpase
AOD63_RS02280	COG0697	spore germination
AOD63_RS02300	COG0586	Pfam SNARE associated Golgi protein
AOD63_RS02315	COG3871	stress protein (general stress protein 26)
AOD63_RS02320	COG0387	Pfam Sodium calcium exchanger
AOD63_RS02330	COG0535	radical SAM domain protein
AOD63_RS02355	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOD63_RS02360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOD63_RS02365	COG0582	viral genome integration into host DNA
AOD63_RS02370	COG1396	sequence-specific DNA binding
AOD63_RS02385	COG1396	sequence-specific DNA binding
AOD63_RS02420	COG1484	DNA-dependent DNA replication
AOD63_RS02515	COG0582	viral genome integration into host DNA
AOD63_RS02520	COG0582	viral genome integration into host DNA
AOD63_RS02645	COG0101	tRNA pseudouridine synthase activity
AOD63_RS02655	COG3829	transcription factor binding
AOD63_RS02665	COG0833	amino acid
AOD63_RS02670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD63_RS02705	COG1263	PTS System
AOD63_RS02705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD63_RS02710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD63_RS02725	COG0463	Glycosyl transferase, family 2
AOD63_RS02740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOD63_RS02740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOD63_RS02760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AOD63_RS02780	COG1228	amidohydrolase
AOD63_RS02785	COG1090	epimerase
AOD63_RS02815	COG1988	membrane-bound metal-dependent
AOD63_RS02820	COG1194	a g-specific adenine glycosylase
AOD63_RS02845	COG1132	(ABC) transporter
AOD63_RS02850	COG4129	membrane
AOD63_RS02855	COG0070	glutamate synthase
AOD63_RS02855	COG0069	glutamate synthase activity
AOD63_RS02855	COG0067	glutamate synthase
AOD63_RS02865	COG4555	ABC transporter
AOD63_RS02885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOD63_RS02890	COG0735	belongs to the Fur family
AOD63_RS03005	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOD63_RS03010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOD63_RS03020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOD63_RS03030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOD63_RS03045	COG2766	serine protein kinase
AOD63_RS03070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOD63_RS03080	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOD63_RS03085	COG2268	Band 7 protein
AOD63_RS03095	COG3290	protein histidine kinase activity
AOD63_RS03105	COG2851	Citrate transporter
AOD63_RS03125	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AOD63_RS03130	COG3842	ATPase activity
AOD63_RS03135	COG1175	transmembrane transport
AOD63_RS03140	COG0395	ABC-type sugar transport system, permease component
AOD63_RS03150	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOD63_RS03155	COG0745	RESPONSE REGULATOR receiver
AOD63_RS03160	COG5002	protein histidine kinase activity
AOD63_RS03170	COG4990	cell redox homeostasis
AOD63_RS03180	COG3290	protein histidine kinase activity
AOD63_RS03185	COG4565	transcriptional regulatory protein
AOD63_RS03190	COG3493	citrate carrier protein
AOD63_RS03195	COG0281	malic enzyme
AOD63_RS03210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS03220	COG5002	protein histidine kinase activity
AOD63_RS03225	COG0745	RESPONSE REGULATOR receiver
AOD63_RS03235	COG0456	acetyltransferase
AOD63_RS03235	COG0454	-acetyltransferase
AOD63_RS03240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOD63_RS03245	COG3383	formate dehydrogenase (NAD+) activity
AOD63_RS03250	COG2427	Protein of unknown function (DUF1641)
AOD63_RS03265	COG0531	amino acid
AOD63_RS03270	COG0640	Transcriptional regulator
AOD63_RS03275	COG2217	Heavy metal translocating P-type atpase
AOD63_RS03280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOD63_RS03290	COG3227	Zinc metalloprotease (Elastase)
AOD63_RS03310	COG2720	vancomycin resistance protein
AOD63_RS03315	COG1316	TRANSCRIPTIONal
AOD63_RS03320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS03325	COG0346	lactoylglutathione lyase activity
AOD63_RS03330	COG1253	flavin adenine dinucleotide binding
AOD63_RS03335	COG1027	Aspartate ammonia-lyase
AOD63_RS03340	COG1620	l-lactate permease
AOD63_RS03355	COG3104	oligopeptide transport
AOD63_RS03360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS03365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS03380	COG2226	methyltransferase
AOD63_RS03385	COG0156	8-amino-7-oxononanoate synthase activity
AOD63_RS03400	COG4548	von Willebrand factor, type A
AOD63_RS03405	COG0714	Associated with various cellular activities
AOD63_RS03410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD63_RS03430	COG0531	amino acid
AOD63_RS03435	COG2188	Transcriptional regulator
AOD63_RS03440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD63_RS03440	COG1263	PTS System
AOD63_RS03445	COG0366	Alpha amylase catalytic
AOD63_RS03460	COG0697	spore germination
AOD63_RS03470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOD63_RS03475	COG1115	amino acid carrier protein
AOD63_RS03480	COG1126	abc transporter atp-binding protein
AOD63_RS03485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD63_RS03490	COG0765	amino acid transport
AOD63_RS03495	COG0765	amino acid transport
AOD63_RS03500	COG0833	amino acid
AOD63_RS03525	COG2378	regulation of single-species biofilm formation
AOD63_RS03530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOD63_RS03535	COG5002	protein histidine kinase activity
AOD63_RS03550	COG0659	secondary active sulfate transmembrane transporter activity
AOD63_RS03565	COG0747	negative chemotaxis
AOD63_RS03575	COG0601	transmembrane transport
AOD63_RS03580	COG4608	Belongs to the ABC transporter superfamily
AOD63_RS03590	COG2271	Major facilitator Superfamily
AOD63_RS03595	COG1846	Transcriptional regulator
AOD63_RS03600	COG0477	Major facilitator Superfamily
AOD63_RS03605	COG0477	Major facilitator Superfamily
AOD63_RS03610	COG1609	Transcriptional regulator
AOD63_RS03615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOD63_RS03630	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOD63_RS03635	COG1879	ABC-type sugar transport system periplasmic component
AOD63_RS03660	COG1063	alcohol dehydrogenase
AOD63_RS03675	COG3568	Endonuclease Exonuclease Phosphatase
AOD63_RS03700	COG1968	undecaprenyl-diphosphatase activity
AOD63_RS03705	COG0840	transmembrane signaling receptor activity
AOD63_RS03710	COG3584	3D domain protein
AOD63_RS03710	COG1388	LysM domain
AOD63_RS03715	COG1476	TRANSCRIPTIONal
AOD63_RS03730	COG3104	oligopeptide transport
AOD63_RS03735	COG1114	Component of the transport system for branched-chain amino acids
AOD63_RS03750	COG1113	amino acid transport
AOD63_RS03755	COG2252	PERMEase
AOD63_RS03780	COG0569	domain protein
AOD63_RS03780	COG0475	glutathione-regulated potassium exporter activity
AOD63_RS03795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOD63_RS03800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOD63_RS03805	COG0833	amino acid
AOD63_RS03810	COG4990	cell redox homeostasis
AOD63_RS03825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD63_RS03830	COG0697	spore germination
AOD63_RS03835	COG0531	amino acid
AOD63_RS03850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOD63_RS03855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOD63_RS03860	COG1918	ferrous iron import across plasma membrane
AOD63_RS03860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOD63_RS03865	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOD63_RS03870	COG0573	inorganic phosphate transmembrane transporter activity
AOD63_RS03875	COG0581	inorganic phosphate transmembrane transporter activity
AOD63_RS03885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOD63_RS04000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AOD63_RS04025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOD63_RS04030	COG1116	anion transmembrane transporter activity
AOD63_RS04035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD63_RS04040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOD63_RS04045	COG0352	thiamine-phosphate diphosphorylase activity
AOD63_RS04050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD63_RS04055	COG2104	thiamine diphosphate biosynthetic process
AOD63_RS04065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD63_RS04070	COG0351	phosphomethylpyrimidine kinase
AOD63_RS04110	COG2205	protein histidine kinase activity
AOD63_RS04115	COG2814	Major facilitator Superfamily
AOD63_RS04120	COG1846	Transcriptional regulator
AOD63_RS04135	COG2252	PERMEase
AOD63_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS04155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOD63_RS04160	COG1621	beta-fructofuranosidase activity
AOD63_RS04165	COG1263	PTS System
AOD63_RS04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD63_RS04170	COG1609	Transcriptional regulator
AOD63_RS04180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD63_RS04185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AOD63_RS04225	COG0778	Nitroreductase
AOD63_RS04230	COG2719	SpoVR family
AOD63_RS04255	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOD63_RS04260	COG1937	Protein conserved in bacteria
AOD63_RS04265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD63_RS04265	COG0425	Belongs to the sulfur carrier protein TusA family
AOD63_RS04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD63_RS04270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS04275	COG0425	Belongs to the sulfur carrier protein TusA family
AOD63_RS04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD63_RS04290	COG2210	Belongs to the sulfur carrier protein TusA family
AOD63_RS04295	COG0730	response to heat
AOD63_RS04305	COG1316	TRANSCRIPTIONal
AOD63_RS04310	COG0604	alcohol dehydrogenase
AOD63_RS04315	COG1283	sodium-dependent phosphate transmembrane transporter activity
AOD63_RS04330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOD63_RS04330	COG3711	transcriptional antiterminator
AOD63_RS04335	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOD63_RS04340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOD63_RS04360	COG3584	3D domain protein
AOD63_RS04360	COG1388	LysM domain
AOD63_RS04365	COG0577	efflux transmembrane transporter activity
AOD63_RS04370	COG1136	(ABC) transporter
AOD63_RS04380	COG5522	Integral membrane protein (intg_mem_TP0381)
AOD63_RS04395	COG1114	Component of the transport system for branched-chain amino acids
AOD63_RS04400	COG3546	catalase activity
AOD63_RS04435	COG0586	Pfam SNARE associated Golgi protein
AOD63_RS04470	COG0531	amino acid
AOD63_RS04475	COG0475	glutathione-regulated potassium exporter activity
AOD63_RS04485	COG1737	Transcriptional regulator
AOD63_RS04495	COG1263	PTS System
AOD63_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD63_RS04505	COG2259	Doxx family
AOD63_RS04520	COG0697	spore germination
AOD63_RS04525	COG1522	sequence-specific DNA binding
AOD63_RS04540	COG2076	Multidrug Resistance protein
AOD63_RS04545	COG1309	transcriptional regulator
AOD63_RS04550	COG2814	Major facilitator Superfamily
AOD63_RS04555	COG1733	regulation of RNA biosynthetic process
AOD63_RS04565	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOD63_RS04570	COG4533	DNA binding
AOD63_RS04575	COG2211	Major facilitator Superfamily
AOD63_RS04585	COG0693	protein deglycase activity
AOD63_RS04590	COG0753	catalase activity
AOD63_RS04600	COG0531	amino acid
AOD63_RS04605	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOD63_RS04615	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS04625	COG1132	(ABC) transporter
AOD63_RS04635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD63_RS04640	COG0765	amino acid transport
AOD63_RS04645	COG1126	abc transporter atp-binding protein
AOD63_RS04660	COG0189	ligase activity
AOD63_RS04690	COG0028	Belongs to the TPP enzyme family
AOD63_RS04695	COG3527	Alpha-acetolactate decarboxylase
AOD63_RS04710	COG0561	phosphatase activity
AOD63_RS04725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOD63_RS04740	COG0659	secondary active sulfate transmembrane transporter activity
AOD63_RS04760	COG0653	protein targeting
AOD63_RS04765	COG2244	polysaccharide biosynthetic process
AOD63_RS04775	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS04780	COG4196	transglutaminase domain protein
AOD63_RS04795	COG1696	Membrane protein involved in D-alanine export
AOD63_RS04810	COG1024	Enoyl-CoA hydratase
AOD63_RS04830	COG1363	Peptidase, m42
AOD63_RS04850	COG3938	Belongs to the proline racemase family
AOD63_RS04890	COG0601	transmembrane transport
AOD63_RS04895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD63_RS04905	COG4608	Belongs to the ABC transporter superfamily
AOD63_RS04935	COG0477	Major facilitator Superfamily
AOD63_RS04940	COG3290	protein histidine kinase activity
AOD63_RS04945	COG4565	transcriptional regulatory protein
AOD63_RS04950	COG3181	Tripartite tricarboxylate transporter family receptor
AOD63_RS04980	COG4978	Transcriptional regulator
AOD63_RS04980	COG0789	Transcriptional regulator
AOD63_RS04995	COG0305	Participates in initiation and elongation during chromosome replication
AOD63_RS05035	COG0477	Major facilitator Superfamily
AOD63_RS05085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOD63_RS05085	COG3320	Male sterility
AOD63_RS05090	COG1309	transcriptional regulator
AOD63_RS05110	COG1183	phosphatidylcholine synthase activity
AOD63_RS05130	COG2376	Dihydroxyacetone kinase
AOD63_RS05140	COG2376	Dihydroxyacetone kinase
AOD63_RS05145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOD63_RS05150	COG1959	2 iron, 2 sulfur cluster binding
AOD63_RS05175	COG2770	Histidine kinase
AOD63_RS05175	COG3437	response regulator, receiver
AOD63_RS05225	COG3237	CsbD-like
AOD63_RS05250	COG1191	sigma factor activity
AOD63_RS05260	COG2208	phosphoserine phosphatase activity
AOD63_RS05265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOD63_RS05270	COG2198	Histidine kinase
AOD63_RS05270	COG2205	protein histidine kinase activity
AOD63_RS05270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD63_RS05270	COG0784	Response regulator, receiver
AOD63_RS05330	COG0420	3'-5' exonuclease activity
AOD63_RS05335	COG4717	serine-type aminopeptidase activity
AOD63_RS05355	COG1309	transcriptional regulator
AOD63_RS05360	COG2814	Major facilitator Superfamily
AOD63_RS05365	COG0346	lactoylglutathione lyase activity
AOD63_RS05370	COG0346	lactoylglutathione lyase activity
AOD63_RS05375	COG0457	Tetratricopeptide repeat
AOD63_RS05380	COG2267	carboxylic ester hydrolase activity
AOD63_RS05400	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AOD63_RS05405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOD63_RS05415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOD63_RS05455	COG0477	Major facilitator Superfamily
AOD63_RS05460	COG0477	Major facilitator Superfamily
AOD63_RS05470	COG3973	AAA domain
AOD63_RS05475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOD63_RS05500	COG4980	gas vesicle protein
AOD63_RS05505	COG0537	adenosine 5'-monophosphoramidase activity
AOD63_RS05510	COG1131	(ABC) transporter
AOD63_RS05515	COG4473	ABC transporter
AOD63_RS05525	COG1309	transcriptional regulator
AOD63_RS05535	COG3402	PFAM membrane-flanked domain
AOD63_RS05545	COG3428	Bacterial PH domain
AOD63_RS05585	COG3402	PFAM membrane-flanked domain
AOD63_RS05590	COG3428	Bacterial PH domain
AOD63_RS05595	COG2329	Antibiotic biosynthesis monooxygenase
AOD63_RS05600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD63_RS05605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOD63_RS05610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOD63_RS05615	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOD63_RS05650	COG1309	transcriptional regulator
AOD63_RS05655	COG1511	domain protein
AOD63_RS05690	COG1234	tRNA 3'-trailer cleavage
AOD63_RS05695	COG0095	Lipoate-protein ligase
AOD63_RS05705	COG0318	PFAM AMP-dependent synthetase and ligase
AOD63_RS05735	COG3209	COG3209 Rhs family protein
AOD63_RS05780	COG1408	metallophosphoesterase
AOD63_RS05785	COG1078	dGTPase activity
AOD63_RS05795	COG1595	DNA-templated transcription, initiation
AOD63_RS05800	COG3708	Transcriptional regulator
AOD63_RS05800	COG2207	Transcriptional regulator
AOD63_RS05815	COG2205	protein histidine kinase activity
AOD63_RS05820	COG0745	RESPONSE REGULATOR receiver
AOD63_RS05845	COG0501	Belongs to the peptidase M48B family
AOD63_RS05850	COG0840	transmembrane signaling receptor activity
AOD63_RS05855	COG0697	spore germination
AOD63_RS05875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOD63_RS05880	COG2224	Isocitrate lyase
AOD63_RS05905	COG4903	ComK protein
AOD63_RS05910	COG0398	Pfam SNARE associated Golgi protein
AOD63_RS05920	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AOD63_RS05925	COG1074	ATP-dependent DNA helicase activity
AOD63_RS05970	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOD63_RS05995	COG0367	asparagine synthase
AOD63_RS06000	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOD63_RS06005	COG0753	catalase activity
AOD63_RS06010	COG0004	ammonium transporteR
AOD63_RS06035	COG2996	Protein conserved in bacteria
AOD63_RS06045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOD63_RS06055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS06070	COG0561	phosphatase activity
AOD63_RS06085	COG0542	response to heat
AOD63_RS06095	COG2267	carboxylic ester hydrolase activity
AOD63_RS06110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD63_RS06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOD63_RS06120	COG5504	Zn-dependent protease
AOD63_RS06130	COG0180	Tryptophanyl-tRNA synthetase
AOD63_RS06140	COG4166	transmembrane transport
AOD63_RS06145	COG0601	transmembrane transport
AOD63_RS06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD63_RS06155	COG0444	Belongs to the ABC transporter superfamily
AOD63_RS06160	COG4608	Belongs to the ABC transporter superfamily
AOD63_RS06165	COG0534	Mate efflux family protein
AOD63_RS06170	COG4166	transmembrane transport
AOD63_RS06190	COG0861	Integral membrane protein TerC family
AOD63_RS06195	COG4862	establishment of competence for transformation
AOD63_RS06200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD63_RS06210	COG1164	Oligoendopeptidase f
AOD63_RS06220	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOD63_RS06225	COG2346	COG2346, Truncated hemoglobins
AOD63_RS06230	COG4116	CYTH
AOD63_RS06240	COG2357	RelA SpoT domain protein
AOD63_RS06250	COG0564	pseudouridine synthase activity
AOD63_RS06265	COG0772	Belongs to the SEDS family
AOD63_RS06270	COG0463	Glycosyl transferase, family 2
AOD63_RS06270	COG1216	Glycosyl transferase, family 2
AOD63_RS06290	COG0457	Tetratricopeptide repeat
AOD63_RS06290	COG0463	Glycosyl transferase, family 2
AOD63_RS06310	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AOD63_RS06325	COG1091	dTDP-4-dehydrorhamnose reductase activity
AOD63_RS06370	COG2153	protein acetylation
AOD63_RS06380	COG2382	esterase
AOD63_RS06395	COG5492	domain, Protein
AOD63_RS06400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD63_RS06415	COG0512	Glutamine amidotransferase of anthranilate synthase
AOD63_RS06415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOD63_RS06450	COG1620	l-lactate permease
AOD63_RS06455	COG5634	Uncharacterized conserved protein (DUF2278)
AOD63_RS06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD63_RS06515	COG1476	TRANSCRIPTIONal
AOD63_RS06575	COG2226	methyltransferase
AOD63_RS06585	COG1686	Belongs to the peptidase S11 family
AOD63_RS06590	COG0681	Belongs to the peptidase S26 family
AOD63_RS06625	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS06630	COG3842	ATPase activity
AOD63_RS06635	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOD63_RS06640	COG1177	transmembrane transport
AOD63_RS06645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOD63_RS06655	COG2409	Drug exporters of the RND superfamily
AOD63_RS06665	COG0564	pseudouridine synthase activity
AOD63_RS06675	COG2340	Cysteine-rich secretory protein family
AOD63_RS06680	COG0247	lactate metabolic process
AOD63_RS06685	COG0277	FAD linked oxidase domain protein
AOD63_RS06690	COG3835	regulator
AOD63_RS06700	COG0745	RESPONSE REGULATOR receiver
AOD63_RS06705	COG5002	protein histidine kinase activity
AOD63_RS06710	COG2186	Transcriptional regulator
AOD63_RS06730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AOD63_RS06740	COG2116	formate transmembrane transporter activity
AOD63_RS06745	COG0861	Integral membrane protein TerC family
AOD63_RS06750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOD63_RS06760	COG2030	dehydratase
AOD63_RS06780	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS06785	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOD63_RS06790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD63_RS06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOD63_RS06810	COG1840	ABC-type Fe3 transport system, periplasmic component
AOD63_RS06840	COG1349	DNA-binding transcription factor activity
AOD63_RS06865	COG2861	carbohydrate metabolic process
AOD63_RS06875	COG3852	Histidine kinase
AOD63_RS06880	COG1846	Transcriptional regulator
AOD63_RS06890	COG2318	DinB family
AOD63_RS06900	COG5002	protein histidine kinase activity
AOD63_RS06910	COG0720	synthase
AOD63_RS06925	COG4873	Protein conserved in bacteria
AOD63_RS06960	COG1780	Probably involved in ribonucleotide reductase function
AOD63_RS06975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOD63_RS06980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOD63_RS06985	COG1725	Transcriptional regulator
AOD63_RS06990	COG1131	(ABC) transporter
AOD63_RS07000	COG1131	(ABC) transporter
AOD63_RS07005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AOD63_RS07020	COG1522	sequence-specific DNA binding
AOD63_RS07030	COG1335	isochorismatase
AOD63_RS07040	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOD63_RS07045	COG2070	2-Nitropropane dioxygenase
AOD63_RS07050	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AOD63_RS07060	COG1696	Membrane protein involved in D-alanine export
AOD63_RS07085	COG0716	FMN binding
AOD63_RS07100	COG3173	Aminoglycoside phosphotransferase
AOD63_RS07120	COG0534	Mate efflux family protein
AOD63_RS07125	COG1968	undecaprenyl-diphosphatase activity
AOD63_RS07140	COG1846	Transcriptional regulator
AOD63_RS07150	COG1301	dicarboxylic acid transport
AOD63_RS07155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOD63_RS07160	COG4709	membrane
AOD63_RS07165	COG3874	Sporulation protein YtfJ
AOD63_RS07195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD63_RS07200	COG0028	Belongs to the TPP enzyme family
AOD63_RS07205	COG0440	acetolactate synthase activity
AOD63_RS07210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOD63_RS07220	COG0473	3-isopropylmalate dehydrogenase activity
AOD63_RS07245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOD63_RS07280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOD63_RS07295	COG1183	phosphatidylcholine synthase activity
AOD63_RS07300	COG1368	sulfuric ester hydrolase activity
AOD63_RS07310	COG0019	diaminopimelate decarboxylase activity
AOD63_RS07330	COG0529	Catalyzes the synthesis of activated sulfate
AOD63_RS07335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOD63_RS07355	COG1648	precorrin-2 dehydrogenase activity
AOD63_RS07365	COG0733	neurotransmitter:sodium symporter activity
AOD63_RS07385	COG1757	Na H antiporter
AOD63_RS07400	COG4758	membrane
AOD63_RS07405	COG4585	Histidine kinase
AOD63_RS07410	COG2197	response regulator
AOD63_RS07420	COG1114	Component of the transport system for branched-chain amino acids
AOD63_RS07430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOD63_RS07455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOD63_RS07455	COG1017	nitric oxide dioxygenase activity
AOD63_RS07475	COG0730	response to heat
AOD63_RS07480	COG0306	phosphate transporter
AOD63_RS07485	COG1392	Phosphate transport regulator
AOD63_RS07490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD63_RS07505	COG3852	Histidine kinase
AOD63_RS07510	COG1801	Protein of unknown function DUF72
AOD63_RS07520	COG0582	viral genome integration into host DNA
AOD63_RS07525	COG5002	protein histidine kinase activity
AOD63_RS07545	COG0392	lysyltransferase activity
AOD63_RS07545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOD63_RS07560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOD63_RS07565	COG1686	Belongs to the peptidase S11 family
AOD63_RS07570	COG2715	membrane protein required for spore maturation
AOD63_RS07575	COG0700	Nucleoside recognition
AOD63_RS07580	COG1187	pseudouridine synthase activity
AOD63_RS07590	COG1333	cytochrome c biogenesis protein
AOD63_RS07595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOD63_RS07600	COG0745	RESPONSE REGULATOR receiver
AOD63_RS07605	COG5002	protein histidine kinase activity
AOD63_RS07610	COG2096	Adenosyltransferase
AOD63_RS07625	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AOD63_RS07630	COG1141	Ferredoxin
AOD63_RS07635	COG4955	Helix-turn-helix domain
AOD63_RS07640	COG0514	ATP-dependent DNA helicase (RecQ)
AOD63_RS07645	COG1266	CAAX protease self-immunity
AOD63_RS07665	COG4862	establishment of competence for transformation
AOD63_RS07670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOD63_RS07690	COG0492	ferredoxin-NADP+ reductase activity
AOD63_RS07695	COG0252	asparaginase activity
AOD63_RS07765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOD63_RS07780	COG0142	geranyltranstransferase activity
AOD63_RS07790	COG0142	geranyltranstransferase activity
AOD63_RS07810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOD63_RS07815	COG0457	Tetratricopeptide repeat
AOD63_RS07835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOD63_RS07845	COG4347	Protein of unknown function (DUF1405)
AOD63_RS07860	COG2738	Putative neutral zinc metallopeptidase
AOD63_RS07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS07875	COG1694	Mazg nucleotide pyrophosphohydrolase
AOD63_RS07890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOD63_RS07895	COG0438	transferase activity, transferring glycosyl groups
AOD63_RS07935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOD63_RS07935	COG1199	ATP-dependent helicase activity
AOD63_RS07955	COG3935	DnaD domain protein
AOD63_RS07960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOD63_RS07970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD63_RS07970	COG4499	WXG100 protein secretion system (Wss), protein YukC
AOD63_RS08025	COG0116	Belongs to the methyltransferase superfamily
AOD63_RS08035	COG1199	ATP-dependent helicase activity
AOD63_RS08040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AOD63_RS08050	COG3173	Aminoglycoside phosphotransferase
AOD63_RS08055	COG0024	Methionine aminopeptidase
AOD63_RS08065	COG2233	PERMEase
AOD63_RS08070	COG2311	Membrane
AOD63_RS08075	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOD63_RS08085	COG0456	acetyltransferase
AOD63_RS08120	COG0754	glutathionylspermidine amidase activity
AOD63_RS08135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOD63_RS08160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOD63_RS08175	COG1215	transferase activity, transferring glycosyl groups
AOD63_RS08180	COG0438	transferase activity, transferring glycosyl groups
AOD63_RS08195	COG0454	-acetyltransferase
AOD63_RS08215	COG0328	RNA-DNA hybrid ribonuclease activity
AOD63_RS08255	COG1280	lysine exporter protein (LysE YggA)
AOD63_RS08270	COG3162	membrane
AOD63_RS08275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD63_RS08280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOD63_RS08290	COG0475	glutathione-regulated potassium exporter activity
AOD63_RS08295	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOD63_RS08300	COG0789	Transcriptional regulator
AOD63_RS08300	COG4978	Transcriptional regulator
AOD63_RS08310	COG2323	membrane
AOD63_RS08315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AOD63_RS08370	COG1923	regulation of RNA biosynthetic process
AOD63_RS08380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOD63_RS08385	COG1360	Flagellar Motor Protein
AOD63_RS08390	COG2201	protein-glutamate methylesterase activity
AOD63_RS08400	COG1776	CheC inhibitor of MCP methylation
AOD63_RS08400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOD63_RS08415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOD63_RS08435	COG1256	bacterial-type flagellum assembly
AOD63_RS08440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOD63_RS08465	COG1815	bacterial-type flagellum-dependent cell motility
AOD63_RS08470	COG1558	bacterial-type flagellum-dependent cell motility
AOD63_RS08480	COG1766	The M ring may be actively involved in energy transduction
AOD63_RS08490	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOD63_RS08500	COG1157	protein secretion by the type III secretion system
AOD63_RS08550	COG0463	Glycosyl transferase, family 2
AOD63_RS08580	COG0457	Tetratricopeptide repeat
AOD63_RS08580	COG0463	Glycosyl transferase, family 2
AOD63_RS08605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOD63_RS08610	COG0741	lytic transglycosylase activity
AOD63_RS08625	COG1776	CheC inhibitor of MCP methylation
AOD63_RS08625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOD63_RS08635	COG1338	Plays a role in the flagellum-specific transport system
AOD63_RS08640	COG1987	bacterial-type flagellum assembly
AOD63_RS08650	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOD63_RS08655	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOD63_RS08665	COG4786	Flagellar basal body rod
AOD63_RS08670	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOD63_RS08695	COG1309	transcriptional regulator
AOD63_RS08715	COG2329	Antibiotic biosynthesis monooxygenase
AOD63_RS08740	COG0583	DNA-binding transcription factor activity
AOD63_RS08745	COG3842	ATPase activity
AOD63_RS08750	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOD63_RS08760	COG1234	tRNA 3'-trailer cleavage
AOD63_RS08785	COG1686	Belongs to the peptidase S11 family
AOD63_RS08795	COG0406	alpha-ribazole phosphatase activity
AOD63_RS08825	COG0367	asparagine synthase
AOD63_RS08855	COG1802	Transcriptional regulator
AOD63_RS08860	COG0697	spore germination
AOD63_RS08865	COG0523	cobalamin synthesis protein
AOD63_RS08870	COG0701	Predicted permease
AOD63_RS08880	COG0438	transferase activity, transferring glycosyl groups
AOD63_RS08880	COG1216	Glycosyl transferase, family 2
AOD63_RS08885	COG1757	Na H antiporter
AOD63_RS08890	COG0114	fumarate hydratase activity
AOD63_RS08920	COG3340	Belongs to the peptidase S51 family
AOD63_RS08940	COG0785	Cytochrome C biogenesis protein
AOD63_RS08975	COG2733	membrane
AOD63_RS09010	COG1131	(ABC) transporter
AOD63_RS09025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD63_RS09030	COG0528	UMP kinase activity
AOD63_RS09040	COG1027	Aspartate ammonia-lyase
AOD63_RS09045	COG0281	malic enzyme
AOD63_RS09050	COG4191	Histidine kinase
AOD63_RS09055	COG0784	Response regulator, receiver
AOD63_RS09060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOD63_RS09120	COG1051	belongs to the nudix hydrolase family
AOD63_RS09125	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS09135	COG2814	Major facilitator Superfamily
AOD63_RS09150	COG1966	Carbon starvation protein
AOD63_RS09165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD63_RS09175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOD63_RS09185	COG2223	nitrite transmembrane transporter activity
AOD63_RS09190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOD63_RS09205	COG2244	polysaccharide biosynthetic process
AOD63_RS09210	COG0733	neurotransmitter:sodium symporter activity
AOD63_RS09220	COG5566	PFAM Mor transcription activator
AOD63_RS09225	COG2323	membrane
AOD63_RS09240	COG2084	Dehydrogenase
AOD63_RS09255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOD63_RS09265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD63_RS09270	COG0028	Belongs to the TPP enzyme family
AOD63_RS09275	COG0440	acetolactate synthase activity
AOD63_RS09280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOD63_RS09290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOD63_RS09315	COG2814	Major facilitator Superfamily
AOD63_RS09320	COG3384	dioxygenase
AOD63_RS09330	COG3279	Response regulator of the LytR AlgR family
AOD63_RS09335	COG0427	acetyl-CoA hydrolase
AOD63_RS09355	COG1073	alpha beta
AOD63_RS09360	COG4166	transmembrane transport
AOD63_RS09385	COG0535	radical SAM domain protein
AOD63_RS09390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS09410	COG1914	H( )-stimulated, divalent metal cation uptake system
AOD63_RS09425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOD63_RS09460	COG2390	Transcriptional regulator
AOD63_RS09470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS09475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AOD63_RS09490	COG4224	UPF0291 protein
AOD63_RS09510	COG0006	proline dipeptidase activity
AOD63_RS09515	COG2132	Multicopper oxidase
AOD63_RS09530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOD63_RS09545	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOD63_RS09560	COG1276	copper resistance
AOD63_RS09560	COG2372	response to copper ion
AOD63_RS09565	COG4549	nuclear export factor GLE1
AOD63_RS09575	COG0697	spore germination
AOD63_RS09580	COG0583	DNA-binding transcription factor activity
AOD63_RS09585	COG1959	2 iron, 2 sulfur cluster binding
AOD63_RS09590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOD63_RS09595	COG0778	Nitroreductase
AOD63_RS09610	COG0628	permease
AOD63_RS09620	COG1231	oxidoreductase activity
AOD63_RS09625	COG0523	cobalamin synthesis protein
AOD63_RS09640	COG0318	PFAM AMP-dependent synthetase and ligase
AOD63_RS09645	COG2030	dehydratase
AOD63_RS09650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD63_RS09660	COG0411	ABC transporter
AOD63_RS09680	COG0583	DNA-binding transcription factor activity
AOD63_RS09700	COG1846	Transcriptional regulator
AOD63_RS09710	COG1271	oxidase subunit
AOD63_RS09715	COG1294	oxidase, subunit
AOD63_RS09720	COG4988	ABC transporter
AOD63_RS09725	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOD63_RS09745	COG1686	Belongs to the peptidase S11 family
AOD63_RS09760	COG0791	NLP P60 protein
AOD63_RS09760	COG1388	LysM domain
AOD63_RS09770	COG1132	(ABC) transporter
AOD63_RS09775	COG1132	(ABC) transporter
AOD63_RS09780	COG0745	RESPONSE REGULATOR receiver
AOD63_RS09785	COG5002	protein histidine kinase activity
AOD63_RS09795	COG0300	oxidoreductase activity
AOD63_RS09830	COG0460	homoserine dehydrogenase
AOD63_RS09855	COG1316	TRANSCRIPTIONal
AOD63_RS09865	COG0745	RESPONSE REGULATOR receiver
AOD63_RS09870	COG5002	protein histidine kinase activity
AOD63_RS09885	COG1285	pathogenesis
AOD63_RS09890	COG1247	-acetyltransferase
AOD63_RS09910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOD63_RS09920	COG1082	Xylose isomerase domain protein TIM barrel
AOD63_RS09935	COG1279	arginine transmembrane transporter activity
AOD63_RS09945	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOD63_RS09985	COG2002	toxin-antitoxin pair type II binding
AOD63_RS09990	COG1404	Belongs to the peptidase S8 family
AOD63_RS09995	COG0640	Transcriptional regulator
AOD63_RS10000	COG0667	Aldo Keto reductase
AOD63_RS10005	COG2814	Major facilitator Superfamily
AOD63_RS10030	COG0840	transmembrane signaling receptor activity
AOD63_RS10050	COG3949	Membrane
AOD63_RS10055	COG0783	Belongs to the Dps family
AOD63_RS10070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOD63_RS10080	COG1231	oxidoreductase activity
AOD63_RS10090	COG4989	oxidoreductase activity
AOD63_RS10095	COG0523	cobalamin synthesis protein
AOD63_RS10100	COG0456	acetyltransferase
AOD63_RS10160	COG3443	Belongs to the bacterial solute-binding protein 9 family
AOD63_RS10160	COG0803	Belongs to the bacterial solute-binding protein 9 family
AOD63_RS10170	COG0702	epimerase
AOD63_RS10180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOD63_RS10190	COG4166	transmembrane transport
AOD63_RS10205	COG0406	alpha-ribazole phosphatase activity
AOD63_RS10215	COG5337	Spore coat protein CotH
AOD63_RS10220	COG1051	belongs to the nudix hydrolase family
AOD63_RS10225	COG0586	Pfam SNARE associated Golgi protein
AOD63_RS10230	COG2244	polysaccharide biosynthetic process
AOD63_RS10240	COG0701	Predicted permease
AOD63_RS10245	COG3689	TIGRFAM TIGR03943 family protein
AOD63_RS10250	COG1607	acyl-coa hydrolase
AOD63_RS10255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD63_RS10270	COG0702	epimerase
AOD63_RS10275	COG2839	Protein conserved in bacteria
AOD63_RS10280	COG1253	flavin adenine dinucleotide binding
AOD63_RS10295	COG1114	Component of the transport system for branched-chain amino acids
AOD63_RS10300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD63_RS10320	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS10330	COG1876	peptidase activity
AOD63_RS10340	COG0154	amidase activity
AOD63_RS10345	COG2211	Major facilitator Superfamily
AOD63_RS10365	COG0561	phosphatase activity
AOD63_RS10375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOD63_RS10380	COG4106	trans-aconitate 2-methyltransferase activity
AOD63_RS10395	COG1819	glycosyl
AOD63_RS10400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS10405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS10430	COG0456	acetyltransferase
AOD63_RS10480	COG3874	Sporulation protein YtfJ
AOD63_RS10505	COG2226	methyltransferase
AOD63_RS10525	COG1082	Xylose isomerase domain protein TIM barrel
AOD63_RS10530	COG0346	lactoylglutathione lyase activity
AOD63_RS10540	COG0604	alcohol dehydrogenase
AOD63_RS10545	COG1595	DNA-templated transcription, initiation
AOD63_RS10570	COG0386	Belongs to the glutathione peroxidase family
AOD63_RS10575	COG1305	Transglutaminase-like
AOD63_RS10580	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AOD63_RS10585	COG0714	Associated with various cellular activities
AOD63_RS10600	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AOD63_RS10605	COG1140	nitrate reductase beta subunit
AOD63_RS10610	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AOD63_RS10615	COG2181	nitrate reductase activity
AOD63_RS10635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOD63_RS10640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOD63_RS10645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD63_RS10650	COG0303	'Molybdopterin
AOD63_RS10655	COG0314	molybdopterin synthase activity
AOD63_RS10665	COG2223	nitrite transmembrane transporter activity
AOD63_RS10680	COG1648	precorrin-2 dehydrogenase activity
AOD63_RS10690	COG1587	Uroporphyrinogen-III synthase
AOD63_RS10690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOD63_RS10695	COG2146	nitrite reductase [NAD(P)H] activity
AOD63_RS10700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOD63_RS10705	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AOD63_RS10740	COG2359	stage V sporulation protein S
AOD63_RS10755	COG5632	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS10770	COG1418	mRNA catabolic process
AOD63_RS10775	COG0488	(ABC) transporter
AOD63_RS10790	COG0629	single-stranded DNA binding
AOD63_RS10805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOD63_RS10810	COG1413	lyase activity
AOD63_RS10825	COG2136	Putative SAM-dependent methyltransferase
AOD63_RS10825	COG2521	methyltransferase
AOD63_RS10830	COG0018	arginyl-trna synthetase
AOD63_RS10855	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOD63_RS10870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOD63_RS10875	COG0017	Asparaginyl-tRNA synthetase
AOD63_RS10895	COG1674	ftsk spoiiie
AOD63_RS10995	COG1929	Belongs to the glycerate kinase type-1 family
AOD63_RS11000	COG0471	metal ion transport
AOD63_RS11005	COG0745	RESPONSE REGULATOR receiver
AOD63_RS11010	COG3850	Histidine kinase
AOD63_RS11010	COG5002	protein histidine kinase activity
AOD63_RS11025	COG0733	neurotransmitter:sodium symporter activity
AOD63_RS11050	COG2610	gluconate transmembrane transporter activity
AOD63_RS11055	COG1454	alcohol dehydrogenase
AOD63_RS11060	COG1794	racemase activity, acting on amino acids and derivatives
AOD63_RS11070	COG0456	acetyltransferase
AOD63_RS11085	COG1131	(ABC) transporter
AOD63_RS11090	COG4473	ABC transporter
AOD63_RS11100	COG0546	phosphoglycolate phosphatase activity
AOD63_RS11120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD63_RS11135	COG0768	penicillin binding
AOD63_RS11140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOD63_RS11145	COG0204	Acyl-transferase
AOD63_RS11150	COG1272	protein, Hemolysin III
AOD63_RS11160	COG0805	protein transport
AOD63_RS11170	COG1307	EDD domain protein, DegV family
AOD63_RS11175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOD63_RS11180	COG1999	signal sequence binding
AOD63_RS11185	COG0071	Belongs to the small heat shock protein (HSP20) family
AOD63_RS11190	COG0367	asparagine synthase
AOD63_RS11210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS11215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD63_RS11250	COG0668	transmembrane transport
AOD63_RS11255	COG4585	Histidine kinase
AOD63_RS11255	COG2203	Gaf domain
AOD63_RS11260	COG2197	response regulator
AOD63_RS11270	COG1737	Transcriptional regulator
AOD63_RS11275	COG1064	alcohol dehydrogenase
AOD63_RS11305	COG1070	Carbohydrate kinase
AOD63_RS11310	COG1070	Carbohydrate kinase
AOD63_RS11340	COG1125	glycine betaine transport
AOD63_RS11340	COG0517	IMP dehydrogenase activity
AOD63_RS11345	COG1174	glycine betaine transport
AOD63_RS11380	COG1253	flavin adenine dinucleotide binding
AOD63_RS11385	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS11390	COG5506	Protein of unknown function (DUF1694)
AOD63_RS11405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOD63_RS11410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOD63_RS11415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOD63_RS11420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD63_RS11425	COG0456	acetyltransferase
AOD63_RS11430	COG3829	transcription factor binding
AOD63_RS11435	COG1509	lysine 2,3-aminomutase activity
AOD63_RS11475	COG4326	sporulation control protein
AOD63_RS11480	COG0671	phosphoesterase, PA-phosphatase related
AOD63_RS11485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AOD63_RS11490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD63_RS11520	COG1787	Restriction endonuclease
AOD63_RS11520	COG1715	Restriction endonuclease
AOD63_RS11605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOD63_RS11645	COG4499	WXG100 protein secretion system (Wss), protein YukC
AOD63_RS11645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD63_RS11655	COG2814	Major facilitator Superfamily
AOD63_RS11660	COG4841	protein insertion into membrane
AOD63_RS11665	COG0372	Belongs to the citrate synthase family
AOD63_RS11670	COG2079	MmgE PrpD family protein
AOD63_RS11675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOD63_RS11680	COG1960	acyl-CoA dehydrogenase activity
AOD63_RS11685	COG2084	Dehydrogenase
AOD63_RS11695	COG1280	lysine exporter protein (LysE YggA)
AOD63_RS11700	COG1024	Enoyl-CoA hydratase
AOD63_RS11715	COG0420	3'-5' exonuclease activity
AOD63_RS11720	COG0419	ATPase involved in DNA repair
AOD63_RS11750	COG2223	nitrite transmembrane transporter activity
AOD63_RS11755	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS11760	COG1169	isochorismate synthase
AOD63_RS11765	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOD63_RS11770	COG3433	isochorismatase activity
AOD63_RS11770	COG1535	isochorismatase
AOD63_RS11775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOD63_RS11780	COG3251	PFAM MbtH domain protein
AOD63_RS11785	COG2814	Major facilitator Superfamily
AOD63_RS11800	COG0776	regulation of translation
AOD63_RS11810	COG2318	DinB family
AOD63_RS11820	COG1115	amino acid carrier protein
AOD63_RS11835	COG2329	Antibiotic biosynthesis monooxygenase
AOD63_RS11840	COG1187	pseudouridine synthase activity
AOD63_RS11845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOD63_RS11860	COG0596	Alpha beta hydrolase
AOD63_RS11865	COG2814	Major facilitator Superfamily
AOD63_RS11885	COG2226	methyltransferase
AOD63_RS11930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS11965	COG1247	-acetyltransferase
AOD63_RS11995	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOD63_RS12005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS12015	COG1278	Cold shock
AOD63_RS12030	COG0010	Belongs to the arginase family
AOD63_RS12035	COG0561	phosphatase activity
AOD63_RS12080	COG0583	DNA-binding transcription factor activity
AOD63_RS12085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOD63_RS12100	COG0583	DNA-binding transcription factor activity
AOD63_RS12105	COG2258	MOSC domain
AOD63_RS12120	COG1132	(ABC) transporter
AOD63_RS12125	COG1132	(ABC) transporter
AOD63_RS12145	COG1396	sequence-specific DNA binding
AOD63_RS12170	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AOD63_RS12175	COG1595	DNA-templated transcription, initiation
AOD63_RS12200	COG1649	PFAM Uncharacterised BCR, COG1649
AOD63_RS12225	COG2971	BadF BadG BcrA BcrD
AOD63_RS12230	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOD63_RS12235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOD63_RS12255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS12285	COG1309	transcriptional regulator
AOD63_RS12300	COG0577	efflux transmembrane transporter activity
AOD63_RS12300	COG1136	(ABC) transporter
AOD63_RS12305	COG3615	Tellurite resistance protein tehB
AOD63_RS12305	COG0500	methyltransferase
AOD63_RS12315	COG2226	methyltransferase
AOD63_RS12320	COG3961	Belongs to the TPP enzyme family
AOD63_RS12325	COG1846	Transcriptional regulator
AOD63_RS12365	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOD63_RS12380	COG1595	DNA-templated transcription, initiation
AOD63_RS12390	COG0768	penicillin binding
AOD63_RS12400	COG2367	Beta-lactamase
AOD63_RS12405	COG0671	phosphoesterase, PA-phosphatase related
AOD63_RS12410	COG1609	Transcriptional regulator
AOD63_RS12415	COG2814	Major facilitator Superfamily
AOD63_RS12420	COG0673	inositol 2-dehydrogenase activity
AOD63_RS12430	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS12445	COG0191	fructose-bisphosphate aldolase activity
AOD63_RS12450	COG3718	enzyme involved in inositol metabolism
AOD63_RS12465	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS12475	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS12485	COG0457	Tetratricopeptide repeat
AOD63_RS12490	COG1476	TRANSCRIPTIONal
AOD63_RS12505	COG1876	peptidase activity
AOD63_RS12525	COG1309	transcriptional regulator
AOD63_RS12530	COG0488	(ABC) transporter
AOD63_RS12545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS12555	COG1252	NADH dehydrogenase
AOD63_RS12560	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD63_RS12575	COG1131	(ABC) transporter
AOD63_RS12585	COG1309	transcriptional regulator
AOD63_RS12600	COG1960	acyl-CoA dehydrogenase activity
AOD63_RS12605	COG0439	Biotin carboxylase
AOD63_RS12610	COG0511	ligase activity, forming carbon-carbon bonds
AOD63_RS12615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOD63_RS12620	COG1024	Enoyl-CoA hydratase
AOD63_RS12625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOD63_RS12630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOD63_RS12640	COG1247	-acetyltransferase
AOD63_RS12645	COG0572	uridine kinase
AOD63_RS12655	COG2318	DinB family
AOD63_RS12690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOD63_RS12730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOD63_RS12730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOD63_RS12755	COG2814	Major facilitator Superfamily
AOD63_RS12775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOD63_RS12795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS12810	COG1063	alcohol dehydrogenase
AOD63_RS12825	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOD63_RS12830	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOD63_RS12845	COG3773	Cell wall hydrolase
AOD63_RS12855	COG0745	RESPONSE REGULATOR receiver
AOD63_RS12885	COG1136	(ABC) transporter
AOD63_RS12910	COG0460	homoserine dehydrogenase
AOD63_RS12915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS12925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOD63_RS13000	COG2124	cytochrome p450
AOD63_RS13035	COG0561	phosphatase activity
AOD63_RS13045	COG5002	protein histidine kinase activity
AOD63_RS13050	COG0768	penicillin binding
AOD63_RS13055	COG1819	glycosyl
AOD63_RS13060	COG1794	racemase activity, acting on amino acids and derivatives
AOD63_RS13070	COG1122	ATPase activity
AOD63_RS13080	COG2205	protein histidine kinase activity
AOD63_RS13090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD63_RS13095	COG0604	alcohol dehydrogenase
AOD63_RS13100	COG0768	penicillin binding
AOD63_RS13110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD63_RS13145	COG0693	protein deglycase activity
AOD63_RS13175	COG2814	Major facilitator Superfamily
AOD63_RS13190	COG0584	glycerophosphoryl diester phosphodiesterase
AOD63_RS13210	COG0697	spore germination
AOD63_RS13235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD63_RS13245	COG2223	nitrite transmembrane transporter activity
AOD63_RS13260	COG2816	NAD+ diphosphatase activity
AOD63_RS13265	COG0592	DNA-directed DNA polymerase activity
AOD63_RS13270	COG1051	belongs to the nudix hydrolase family
AOD63_RS13305	COG3878	Protein conserved in bacteria
AOD63_RS13335	COG4667	esterase of the alpha-beta hydrolase superfamily
AOD63_RS13360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOD63_RS13375	COG0322	excinuclease ABC activity
AOD63_RS13415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD63_RS13440	COG1011	Hydrolase
AOD63_RS13460	COG0076	glutamate decarboxylase activity
AOD63_RS13475	COG1523	belongs to the glycosyl hydrolase 13 family
AOD63_RS13480	COG3227	Zinc metalloprotease (Elastase)
AOD63_RS13500	COG0201	protein transport
AOD63_RS13510	COG0697	spore germination
AOD63_RS13515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS13545	COG4129	membrane
AOD63_RS13550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS13565	COG2959	enzyme of heme biosynthesis
AOD63_RS13585	COG3483	tryptophan 2,3-dioxygenase activity
AOD63_RS13590	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AOD63_RS13595	COG3844	kynureninase activity
AOD63_RS13600	COG1309	transcriptional regulator
AOD63_RS13630	COG3284	Transcriptional regulator
AOD63_RS13650	COG1349	DNA-binding transcription factor activity
AOD63_RS13670	COG1959	2 iron, 2 sulfur cluster binding
AOD63_RS13685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOD63_RS13690	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD63_RS13695	COG0022	dehydrogenase e1 component
AOD63_RS13700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOD63_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS13715	COG0456	acetyltransferase
AOD63_RS13715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD63_RS13750	COG4176	ABC-type proline glycine betaine transport system permease component
AOD63_RS13755	COG0517	IMP dehydrogenase activity
AOD63_RS13755	COG4175	Glycine betaine
AOD63_RS13780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AOD63_RS13785	COG2153	protein acetylation
AOD63_RS13790	COG3397	chitin binding
AOD63_RS13805	COG2205	protein histidine kinase activity
AOD63_RS13835	COG2333	competence protein COMEC
AOD63_RS13835	COG0658	competence protein
AOD63_RS13885	COG3973	AAA domain
AOD63_RS13900	COG2105	PFAM AIG2 family protein
AOD63_RS13905	COG0514	ATP-dependent DNA helicase (RecQ)
AOD63_RS13935	COG4637	Psort location Cytoplasmic, score
AOD63_RS13960	COG3397	chitin binding
AOD63_RS13970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOD63_RS13975	COG1115	amino acid carrier protein
AOD63_RS13980	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS13985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOD63_RS13995	COG3938	Belongs to the proline racemase family
AOD63_RS14000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD63_RS14040	COG0586	Pfam SNARE associated Golgi protein
AOD63_RS14055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AOD63_RS14060	COG0519	Catalyzes the synthesis of GMP from XMP
AOD63_RS14065	COG4166	transmembrane transport
AOD63_RS14075	COG4948	Mandelate Racemase Muconate Lactonizing
AOD63_RS14115	COG2936	dipeptidyl-peptidase activity
AOD63_RS14120	COG5002	protein histidine kinase activity
AOD63_RS14125	COG0745	RESPONSE REGULATOR receiver
AOD63_RS14165	COG1307	EDD domain protein, DegV family
AOD63_RS14185	COG2814	Major facilitator Superfamily
AOD63_RS14195	COG1664	Polymer-forming cytoskeletal
AOD63_RS14200	COG0789	Transcriptional regulator
AOD63_RS14205	COG4533	DNA binding
AOD63_RS14210	COG2814	Major facilitator Superfamily
AOD63_RS14210	COG0477	Major facilitator Superfamily
AOD63_RS14230	COG2261	transglycosylase associated protein
AOD63_RS14245	COG2226	methyltransferase
AOD63_RS14280	COG0436	Aminotransferase
AOD63_RS14285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOD63_RS14290	COG5146	pantothenate kinase activity
AOD63_RS14315	COG1131	(ABC) transporter
AOD63_RS14365	COG0628	permease
AOD63_RS14380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOD63_RS14385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD63_RS14390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOD63_RS14395	COG1116	anion transmembrane transporter activity
AOD63_RS14415	COG2816	NAD+ diphosphatase activity
AOD63_RS14435	COG2746	aminoglycoside 3-N-acetyltransferase activity
AOD63_RS14460	COG0697	spore germination
AOD63_RS14465	COG2318	DinB family
AOD63_RS14485	COG4912	Dna alkylation repair
AOD63_RS14505	COG0861	Integral membrane protein TerC family
AOD63_RS14510	COG1368	sulfuric ester hydrolase activity
AOD63_RS14515	COG0488	(ABC) transporter
AOD63_RS14525	COG1033	growth of symbiont in host cell
AOD63_RS14525	COG2409	Drug exporters of the RND superfamily
AOD63_RS14530	COG1033	growth of symbiont in host cell
AOD63_RS14530	COG2409	Drug exporters of the RND superfamily
AOD63_RS14535	COG2409	Drug exporters of the RND superfamily
AOD63_RS14535	COG1033	growth of symbiont in host cell
AOD63_RS14540	COG1309	transcriptional regulator
AOD63_RS14555	COG0287	Prephenate dehydrogenase
AOD63_RS14560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOD63_RS14565	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOD63_RS14570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AOD63_RS14570	COG1605	Chorismate mutase
AOD63_RS14605	COG1388	LysM domain
AOD63_RS14605	COG3584	3D domain protein
AOD63_RS14615	COG1595	DNA-templated transcription, initiation
AOD63_RS14640	COG1879	ABC-type sugar transport system periplasmic component
AOD63_RS14650	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOD63_RS14660	COG2390	Transcriptional regulator
AOD63_RS14695	COG2329	Antibiotic biosynthesis monooxygenase
AOD63_RS14715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS14725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOD63_RS14730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD63_RS14735	COG4187	Peptidase family M20/M25/M40
AOD63_RS14740	COG1414	Transcriptional regulator
AOD63_RS14745	COG0833	amino acid
AOD63_RS14750	COG1690	Belongs to the RtcB family
AOD63_RS14755	COG3239	Fatty acid desaturase
AOD63_RS14760	COG1785	Belongs to the alkaline phosphatase family
AOD63_RS14770	COG3655	Transcriptional regulator
AOD63_RS14785	COG4377	Putative membrane peptidase family (DUF2324)
AOD63_RS14795	COG3279	Response regulator of the LytR AlgR family
AOD63_RS14805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS14810	COG0346	lactoylglutathione lyase activity
AOD63_RS14830	COG0714	Associated with various cellular activities
AOD63_RS14855	COG0463	Glycosyl transferase, family 2
AOD63_RS14880	COG0463	Glycosyl transferase, family 2
AOD63_RS14890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOD63_RS14895	COG0753	catalase activity
AOD63_RS14905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOD63_RS14930	COG0714	Associated with various cellular activities
AOD63_RS14940	COG0778	Nitroreductase
AOD63_RS14945	COG1846	Transcriptional regulator
AOD63_RS14980	COG1725	Transcriptional regulator
AOD63_RS14990	COG0577	efflux transmembrane transporter activity
AOD63_RS14990	COG1136	(ABC) transporter
AOD63_RS15015	COG2207	Transcriptional regulator
AOD63_RS15020	COG0456	acetyltransferase
AOD63_RS15040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS15060	COG0642	Histidine kinase
AOD63_RS15065	COG0745	RESPONSE REGULATOR receiver
AOD63_RS15070	COG0596	Alpha beta hydrolase
AOD63_RS15100	COG0730	response to heat
AOD63_RS15110	COG0833	amino acid
AOD63_RS15120	COG4335	DNA alkylation repair
AOD63_RS15160	COG0768	penicillin binding
AOD63_RS15170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOD63_RS15210	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AOD63_RS15215	COG1414	Transcriptional regulator
AOD63_RS15230	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS15235	COG0640	Transcriptional regulator
AOD63_RS15245	COG1960	acyl-CoA dehydrogenase activity
AOD63_RS15265	COG3314	Sporulation integral membrane protein YlbJ
AOD63_RS15280	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AOD63_RS15295	COG0574	Belongs to the PEP-utilizing enzyme family
AOD63_RS15295	COG3848	Pyruvate phosphate dikinase
AOD63_RS15300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS15315	COG5577	PFAM Coat F domain
AOD63_RS15320	COG3403	YqcI/YcgG family
AOD63_RS15325	COG1280	lysine exporter protein (LysE YggA)
AOD63_RS15360	COG1063	alcohol dehydrogenase
AOD63_RS15375	COG1027	Aspartate ammonia-lyase
AOD63_RS15380	COG0252	asparaginase activity
AOD63_RS15385	COG1396	sequence-specific DNA binding
AOD63_RS15395	COG0322	excinuclease ABC activity
AOD63_RS15400	COG0531	amino acid
AOD63_RS15405	COG1114	Component of the transport system for branched-chain amino acids
AOD63_RS15410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD63_RS15420	COG0281	malic enzyme
AOD63_RS15440	COG0531	amino acid
AOD63_RS15445	COG0697	spore germination
AOD63_RS15450	COG0784	Response regulator, receiver
AOD63_RS15460	COG2066	Belongs to the glutaminase family
AOD63_RS15490	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS15495	COG0753	catalase activity
AOD63_RS15500	COG2267	carboxylic ester hydrolase activity
AOD63_RS15505	COG1335	isochorismatase
AOD63_RS15525	COG0583	DNA-binding transcription factor activity
AOD63_RS15570	COG0415	Belongs to the DNA photolyase family
AOD63_RS15575	COG0288	reversible hydration of carbon dioxide
AOD63_RS15585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOD63_RS15590	COG5609	conserved protein (DUF2294)
AOD63_RS15600	COG1575	Belongs to the MenA family. Type 1 subfamily
AOD63_RS15605	COG2267	carboxylic ester hydrolase activity
AOD63_RS15610	COG0803	Belongs to the bacterial solute-binding protein 9 family
AOD63_RS15615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOD63_RS15620	COG1121	(ABC) transporter
AOD63_RS15650	COG0798	PFAM Bile acid sodium symporter
AOD63_RS15655	COG0346	lactoylglutathione lyase activity
AOD63_RS15660	COG0640	Transcriptional regulator
AOD63_RS15675	COG0443	Heat shock 70 kDa protein
AOD63_RS15690	COG1522	sequence-specific DNA binding
AOD63_RS15705	COG0346	lactoylglutathione lyase activity
AOD63_RS15730	COG2169	Transcriptional regulator
AOD63_RS15775	COG2814	Major facilitator Superfamily
AOD63_RS15800	COG0745	RESPONSE REGULATOR receiver
AOD63_RS15805	COG3850	Histidine kinase
AOD63_RS15805	COG5002	protein histidine kinase activity
AOD63_RS15835	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOD63_RS15860	COG1476	TRANSCRIPTIONal
AOD63_RS15875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS15880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOD63_RS15890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD63_RS15895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOD63_RS15910	COG1136	(ABC) transporter
AOD63_RS15915	COG0577	efflux transmembrane transporter activity
AOD63_RS15935	COG3850	Histidine kinase
AOD63_RS15935	COG5002	protein histidine kinase activity
AOD63_RS15945	COG2364	Membrane
AOD63_RS15950	COG1846	Transcriptional regulator
AOD63_RS15960	COG2808	Putative FMN-binding domain
AOD63_RS15965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS15970	COG2271	Major facilitator Superfamily
AOD63_RS15975	COG1556	Lactate utilization protein
AOD63_RS15980	COG1139	Iron-sulfur cluster binding protein
AOD63_RS15990	COG0583	DNA-binding transcription factor activity
AOD63_RS16000	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOD63_RS16025	COG0738	Major facilitator superfamily
AOD63_RS16030	COG0673	inositol 2-dehydrogenase activity
AOD63_RS16035	COG0561	phosphatase activity
AOD63_RS16045	COG1609	Transcriptional regulator
AOD63_RS16050	COG0457	Tetratricopeptide repeat
AOD63_RS16070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOD63_RS16100	COG0534	Mate efflux family protein
AOD63_RS16115	COG2814	Major facilitator Superfamily
AOD63_RS16120	COG1309	transcriptional regulator
AOD63_RS16135	COG0814	amino acid
AOD63_RS16140	COG1760	l-serine dehydratase
AOD63_RS16145	COG1760	l-serine dehydratase
AOD63_RS16155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOD63_RS16160	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AOD63_RS16170	COG1335	isochorismatase
AOD63_RS16175	COG1522	sequence-specific DNA binding
AOD63_RS16180	COG0531	amino acid
AOD63_RS16195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOD63_RS16215	COG1595	DNA-templated transcription, initiation
AOD63_RS16230	COG0662	Cupin 2, conserved barrel domain protein
AOD63_RS16240	COG2207	Transcriptional regulator
AOD63_RS16240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS16295	COG0477	Major facilitator Superfamily
AOD63_RS16305	COG1846	Transcriptional regulator
AOD63_RS16310	COG2814	Major facilitator Superfamily
AOD63_RS16320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AOD63_RS16325	COG1131	(ABC) transporter
AOD63_RS16345	COG2076	Multidrug Resistance protein
AOD63_RS16350	COG1309	transcriptional regulator
AOD63_RS16365	COG2031	fatty acid transporter
AOD63_RS16375	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOD63_RS16405	COG1122	ATPase activity
AOD63_RS16410	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOD63_RS16425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOD63_RS16430	COG1288	antiporter activity
AOD63_RS16435	COG2356	endonuclease I
AOD63_RS16450	COG3620	sequence-specific DNA binding
AOD63_RS16455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOD63_RS16460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOD63_RS16465	COG0124	histidyl-tRNA synthetase
AOD63_RS16480	COG1733	regulation of RNA biosynthetic process
AOD63_RS16485	COG0778	Nitroreductase
AOD63_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS16515	COG1131	(ABC) transporter
AOD63_RS16540	COG1011	Hydrolase
AOD63_RS16550	COG2365	Tyrosine phosphatase family
AOD63_RS16575	COG0346	lactoylglutathione lyase activity
AOD63_RS16580	COG1940	carbohydrate kinase activity
AOD63_RS16585	COG0738	Major facilitator superfamily
AOD63_RS16590	COG0110	maltose O-acetyltransferase activity
AOD63_RS16605	COG1136	(ABC) transporter
AOD63_RS16605	COG0577	efflux transmembrane transporter activity
AOD63_RS16615	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOD63_RS16620	COG0628	permease
AOD63_RS16640	COG2226	methyltransferase
AOD63_RS16650	COG0477	Major facilitator Superfamily
AOD63_RS16680	COG1253	flavin adenine dinucleotide binding
AOD63_RS16685	COG0789	Transcriptional regulator
AOD63_RS16690	COG0697	spore germination
AOD63_RS16695	COG1357	PFAM Pentapeptide repeats (8 copies)
AOD63_RS16700	COG3813	Protein conserved in bacteria
AOD63_RS16705	COG2706	6-phosphogluconolactonase activity
AOD63_RS16710	COG1070	Carbohydrate kinase
AOD63_RS16720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOD63_RS16725	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AOD63_RS16735	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOD63_RS16740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOD63_RS16745	COG0604	alcohol dehydrogenase
AOD63_RS16750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOD63_RS16760	COG0604	alcohol dehydrogenase
AOD63_RS16760	COG3321	synthase
AOD63_RS16770	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS16795	COG0656	L-ascorbic acid biosynthetic process
AOD63_RS16800	COG2814	Major facilitator Superfamily
AOD63_RS16815	COG0346	lactoylglutathione lyase activity
AOD63_RS16820	COG0814	amino acid
AOD63_RS16845	COG1393	Belongs to the ArsC family
AOD63_RS16855	COG1733	regulation of RNA biosynthetic process
AOD63_RS16860	COG2188	Transcriptional regulator
AOD63_RS16870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOD63_RS16875	COG1733	regulation of RNA biosynthetic process
AOD63_RS16880	COG1733	regulation of RNA biosynthetic process
AOD63_RS16895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS16915	COG0384	phenazine biosynthesis protein PhzF
AOD63_RS16925	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS16935	COG0318	PFAM AMP-dependent synthetase and ligase
AOD63_RS16945	COG1733	regulation of RNA biosynthetic process
AOD63_RS16980	COG1191	sigma factor activity
AOD63_RS16995	COG1309	transcriptional regulator
AOD63_RS17015	COG3152	Membrane
AOD63_RS17040	COG1151	hydroxylamine reductase activity
AOD63_RS17050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS17055	COG3409	Peptidoglycan-binding domain 1 protein
AOD63_RS17055	COG3757	hydrolase, family 25
AOD63_RS17090	COG2072	flavoprotein involved in K transport
AOD63_RS17130	COG1113	amino acid transport
AOD63_RS17135	COG2814	Major facilitator Superfamily
AOD63_RS17170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOD63_RS17175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOD63_RS17195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS17210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS17215	COG3739	integral membrane protein
AOD63_RS17220	COG0384	phenazine biosynthesis protein PhzF
AOD63_RS17250	COG0583	DNA-binding transcription factor activity
AOD63_RS17270	COG1193	negative regulation of DNA recombination
AOD63_RS17285	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AOD63_RS17290	COG1164	Oligoendopeptidase f
AOD63_RS17295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD63_RS17325	COG0584	glycerophosphoryl diester phosphodiesterase
AOD63_RS17350	COG0640	Transcriptional regulator
AOD63_RS17355	COG0604	alcohol dehydrogenase
AOD63_RS17375	COG2808	Putative FMN-binding domain
AOD63_RS17380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD63_RS17390	COG0385	Bile acid
AOD63_RS17395	COG0277	FAD linked oxidase domain protein
AOD63_RS17430	COG1216	Glycosyl transferase, family 2
AOD63_RS17435	COG1024	Enoyl-CoA hydratase
AOD63_RS17445	COG1285	pathogenesis
AOD63_RS17455	COG2514	catechol 2,3-dioxygenase activity
AOD63_RS17460	COG2720	vancomycin resistance protein
AOD63_RS17500	COG0716	FMN binding
AOD63_RS17530	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS17540	COG0165	Argininosuccinate lyase
AOD63_RS17555	COG4145	pantothenate transmembrane transporter activity
AOD63_RS17565	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS17570	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS17580	COG1657	PFAM Prenyltransferase squalene oxidase
AOD63_RS17585	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AOD63_RS17590	COG2962	Rard protein
AOD63_RS17595	COG3326	Membrane
AOD63_RS17610	COG0489	protein tyrosine kinase activity
AOD63_RS17620	COG0314	molybdopterin synthase activity
AOD63_RS17625	COG0303	'Molybdopterin
AOD63_RS17630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD63_RS17635	COG2116	formate transmembrane transporter activity
AOD63_RS17645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOD63_RS17650	COG5609	conserved protein (DUF2294)
AOD63_RS17655	COG2427	Protein of unknown function (DUF1641)
AOD63_RS17660	COG3383	formate dehydrogenase (NAD+) activity
AOD63_RS17670	COG0697	spore germination
AOD63_RS17710	COG2226	methyltransferase
AOD63_RS17715	COG4166	transmembrane transport
AOD63_RS17720	COG4166	transmembrane transport
AOD63_RS17725	COG4166	transmembrane transport
AOD63_RS17730	COG1301	dicarboxylic acid transport
AOD63_RS17735	COG1316	TRANSCRIPTIONal
AOD63_RS17745	COG1595	DNA-templated transcription, initiation
AOD63_RS17770	COG1131	(ABC) transporter
AOD63_RS17780	COG0673	inositol 2-dehydrogenase activity
AOD63_RS17785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOD63_RS17790	COG0187	DNA topoisomerase II activity
AOD63_RS17800	COG1832	CoA-binding protein
AOD63_RS17805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOD63_RS17810	COG0745	RESPONSE REGULATOR receiver
AOD63_RS17825	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOD63_RS17830	COG4841	protein insertion into membrane
AOD63_RS17835	COG0824	Thioesterase
AOD63_RS17865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD63_RS17875	COG2274	protein secretion by the type I secretion system
AOD63_RS17880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOD63_RS17910	COG2211	Major facilitator Superfamily
AOD63_RS17920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOD63_RS17935	COG0183	Belongs to the thiolase family
AOD63_RS17940	COG0318	PFAM AMP-dependent synthetase and ligase
AOD63_RS17945	COG1268	BioY protein
AOD63_RS17950	COG0318	PFAM AMP-dependent synthetase and ligase
AOD63_RS17995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS18005	COG5002	protein histidine kinase activity
AOD63_RS18010	COG0400	carboxylic ester hydrolase activity
AOD63_RS18015	COG0346	lactoylglutathione lyase activity
AOD63_RS18020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD63_RS18025	COG0069	glutamate synthase activity
AOD63_RS18030	COG1902	pentaerythritol trinitrate reductase activity
AOD63_RS18035	COG1329	Transcriptional regulator
AOD63_RS18040	COG0010	Belongs to the arginase family
AOD63_RS18065	COG2226	methyltransferase
AOD63_RS18120	COG4846	Membrane protein involved in cytochrome C biogenesis
AOD63_RS18125	COG0785	Cytochrome C biogenesis protein
AOD63_RS18135	COG0583	DNA-binding transcription factor activity
AOD63_RS18140	COG1380	Effector of murein hydrolase LrgA
AOD63_RS18145	COG1346	cytolysis
AOD63_RS18160	COG0730	response to heat
AOD63_RS18170	COG3409	Peptidoglycan-binding domain 1 protein
AOD63_RS18170	COG5632	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS18185	COG1132	(ABC) transporter
AOD63_RS18190	COG1132	(ABC) transporter
AOD63_RS18225	COG3639	organic phosphonate transmembrane transporter activity
AOD63_RS18230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AOD63_RS18245	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS18255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOD63_RS18275	COG1695	Transcriptional regulator
AOD63_RS18310	COG5632	N-Acetylmuramoyl-L-alanine amidase
AOD63_RS18310	COG3409	Peptidoglycan-binding domain 1 protein
AOD63_RS18310	COG1388	LysM domain
AOD63_RS18315	COG4824	toxin secretion phage lysis holin
AOD63_RS18480	COG1595	DNA-templated transcription, initiation
AOD63_RS18525	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AOD63_RS18605	COG1396	sequence-specific DNA binding
AOD63_RS18630	COG0174	glutamine synthetase
AOD63_RS18635	COG0789	Transcriptional regulator
AOD63_RS18640	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AOD63_RS18650	COG2860	membrane
AOD63_RS18655	COG0464	growth
AOD63_RS18685	COG3584	3D domain protein
AOD63_RS18685	COG1388	LysM domain
AOD63_RS18690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOD63_RS18690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOD63_RS18690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOD63_RS18695	COG1105	Belongs to the carbohydrate kinase PfkB family
AOD63_RS18700	COG1349	DNA-binding transcription factor activity
AOD63_RS18710	COG2322	membrane
AOD63_RS18725	COG1113	amino acid transport
AOD63_RS18735	COG1408	metallophosphoesterase
AOD63_RS18740	COG2116	formate transmembrane transporter activity
AOD63_RS18750	COG2217	Heavy metal translocating P-type atpase
AOD63_RS18755	COG2608	mercury ion transmembrane transporter activity
AOD63_RS18760	COG1937	Protein conserved in bacteria
AOD63_RS18770	COG2819	hydrolase of the alpha beta superfamily
AOD63_RS18775	COG1120	ATPase activity
AOD63_RS18780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS18785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS18790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS18800	COG0708	Exodeoxyribonuclease III
AOD63_RS18805	COG2169	Transcriptional regulator
AOD63_RS18810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOD63_RS18815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOD63_RS18825	COG2364	Membrane
AOD63_RS18840	COG2267	carboxylic ester hydrolase activity
AOD63_RS18845	COG0346	lactoylglutathione lyase activity
AOD63_RS18850	COG3300	MHYT domain
AOD63_RS18850	COG5001	Diguanylate cyclase
AOD63_RS18870	COG1346	cytolysis
AOD63_RS18875	COG1380	Effector of murein hydrolase LrgA
AOD63_RS18880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD63_RS18885	COG0596	Alpha beta hydrolase
AOD63_RS18885	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD63_RS18890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOD63_RS18905	COG1404	Belongs to the peptidase S8 family
AOD63_RS18910	COG3773	Cell wall hydrolase
AOD63_RS18915	COG0562	UDP-galactopyranose mutase
AOD63_RS18920	COG1368	sulfuric ester hydrolase activity
AOD63_RS18925	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOD63_RS18935	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AOD63_RS18960	COG1131	(ABC) transporter
AOD63_RS18980	COG4550	Control of competence regulator ComK, YlbF/YmcA
AOD63_RS18985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOD63_RS18990	COG1013	pyruvate-flavodoxin oxidoreductase activity
AOD63_RS18995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AOD63_RS18995	COG0674	pyruvate-flavodoxin oxidoreductase activity
AOD63_RS19005	COG2359	stage V sporulation protein S
AOD63_RS19010	COG1692	metallophosphoesterase
AOD63_RS19035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOD63_RS19040	COG1426	Protein conserved in bacteria
AOD63_RS19055	COG0300	oxidoreductase activity
AOD63_RS19060	COG0612	Peptidase, M16
AOD63_RS19065	COG0612	Peptidase, M16
AOD63_RS19075	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOD63_RS19080	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOD63_RS19085	COG3845	ABC transporter
AOD63_RS19090	COG1744	ABC transporter substrate-binding protein PnrA-like
AOD63_RS19095	COG2188	Transcriptional regulator
AOD63_RS19100	COG1674	ftsk spoiiie
AOD63_RS19110	COG0740	serine-type endopeptidase activity
AOD63_RS19115	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOD63_RS19130	COG0527	aspartate kinase activity
AOD63_RS19135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOD63_RS19140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOD63_RS19145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOD63_RS19150	COG1873	PFAM PRC-barrel domain
AOD63_RS19155	COG0612	Peptidase, M16
AOD63_RS19160	COG0726	polysaccharide deacetylase
AOD63_RS19175	COG0196	riboflavin kinase activity
AOD63_RS19180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOD63_RS19190	COG1550	Protein conserved in bacteria
AOD63_RS19200	COG1358	cellular component organization or biogenesis
AOD63_RS19205	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AOD63_RS19210	COG0195	Participates in both transcription termination and antitermination
AOD63_RS19230	COG0750	zinc metalloprotease
AOD63_RS19240	COG4589	Belongs to the CDS family
AOD63_RS19245	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOD63_RS19255	COG0528	UMP kinase activity
AOD63_RS19285	COG4974	Belongs to the 'phage' integrase family
AOD63_RS19295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOD63_RS19305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AOD63_RS19345	COG1837	Belongs to the UPF0109 family
AOD63_RS19355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOD63_RS19365	COG0552	protein localization to endoplasmic reticulum
AOD63_RS19370	COG1196	nuclear chromosome segregation
AOD63_RS19380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOD63_RS19385	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS19390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOD63_RS19405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOD63_RS19410	COG1461	Dihydroxyacetone kinase
AOD63_RS19415	COG1302	Protein conserved in bacteria
AOD63_RS19430	COG1564	THIamine pyrophosphokinase
AOD63_RS19435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOD63_RS19440	COG1162	GTPase activity
AOD63_RS19445	COG0515	serine threonine protein kinase
AOD63_RS19445	COG2815	serine threonine protein kinase
AOD63_RS19450	COG0631	protein serine/threonine phosphatase activity
AOD63_RS19460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOD63_RS19460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOD63_RS19470	COG0242	peptide deformylase activity
AOD63_RS19475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOD63_RS19480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOD63_RS19500	COG1561	YicC-like family, N-terminal region
AOD63_RS19505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOD63_RS19515	COG0006	proline dipeptidase activity
AOD63_RS19530	COG3069	C4-dicarboxylate transmembrane transporter activity
AOD63_RS19595	COG0564	pseudouridine synthase activity
AOD63_RS19615	COG3599	regulation of cell shape
AOD63_RS19620	COG2302	S4 RNA-binding domain
AOD63_RS19625	COG0762	integral membrane protein
AOD63_RS19635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOD63_RS19640	COG1496	oxidoreductase activity
AOD63_RS19645	COG1873	PFAM PRC-barrel domain
AOD63_RS19650	COG1191	sigma factor activity
AOD63_RS19655	COG1191	sigma factor activity
AOD63_RS19665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOD63_RS19670	COG0849	cell division
AOD63_RS19675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOD63_RS19680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOD63_RS19690	COG0772	Belongs to the SEDS family
AOD63_RS19705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOD63_RS19710	COG0768	penicillin binding
AOD63_RS19715	COG0768	penicillin binding
AOD63_RS19720	COG4839	cell division protein FtsL
AOD63_RS19735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOD63_RS19750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOD63_RS19755	COG1399	metal-binding, possibly nucleic acid-binding protein
AOD63_RS19805	COG4824	toxin secretion phage lysis holin
AOD63_RS19900	COG1802	Transcriptional regulator
AOD63_RS19900	COG4626	Terminase
AOD63_RS19925	COG0582	viral genome integration into host DNA
AOD63_RS19990	COG0756	dUTP diphosphatase activity
AOD63_RS20000	COG1191	sigma factor activity
AOD63_RS20025	COG1484	DNA-dependent DNA replication
AOD63_RS20055	COG1396	sequence-specific DNA binding
AOD63_RS20065	COG1396	sequence-specific DNA binding
AOD63_RS20080	COG0582	viral genome integration into host DNA
AOD63_RS20090	COG3480	Lon protease (S16) C-terminal proteolytic domain
AOD63_RS20095	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOD63_RS20100	COG3314	Sporulation integral membrane protein YlbJ
AOD63_RS20110	COG0742	ribosomal rna small subunit methyltransferase
AOD63_RS20125	COG3679	Belongs to the UPF0342 family
AOD63_RS20130	COG0406	alpha-ribazole phosphatase activity
AOD63_RS20145	COG2340	Cysteine-rich secretory protein family
AOD63_RS20160	COG3336	cytochrome c oxidase
AOD63_RS20195	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOD63_RS20200	COG0772	Belongs to the SEDS family
AOD63_RS20210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOD63_RS20215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOD63_RS20225	COG4896	Protein conserved in bacteria
AOD63_RS20240	COG1217	gtp-binding protein TYPA
AOD63_RS20250	COG0483	inositol monophosphate 1-phosphatase activity
AOD63_RS20270	COG1982	Orn Lys Arg decarboxylase major
AOD63_RS20315	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD63_RS20320	COG0022	dehydrogenase e1 component
AOD63_RS20325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOD63_RS20335	COG0242	peptide deformylase activity
AOD63_RS20340	COG0561	phosphatase activity
AOD63_RS20350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOD63_RS20355	COG0569	domain protein
AOD63_RS20375	COG0583	DNA-binding transcription factor activity
AOD63_RS20380	COG0517	IMP dehydrogenase activity
AOD63_RS20390	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AOD63_RS20400	COG4703	Protein of unknown function (DUF1797)
AOD63_RS20415	COG2200	EAL domain
AOD63_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS20425	COG1408	metallophosphoesterase
AOD63_RS20435	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOD63_RS20475	COG2814	Major facilitator Superfamily
AOD63_RS20495	COG3209	COG3209 Rhs family protein
AOD63_RS20505	COG2205	protein histidine kinase activity
AOD63_RS20515	COG0436	Aminotransferase
AOD63_RS20520	COG1609	Transcriptional regulator
AOD63_RS20525	COG3833	ABC-type maltose transport systems, permease component
AOD63_RS20530	COG1175	transmembrane transport
AOD63_RS20535	COG2182	Extracellular solute-binding protein
AOD63_RS20545	COG0366	Alpha amylase catalytic
AOD63_RS20550	COG3842	ATPase activity
AOD63_RS20590	COG0183	Belongs to the thiolase family
AOD63_RS20630	COG1695	Transcriptional regulator
AOD63_RS20635	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS20645	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AOD63_RS20655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOD63_RS20660	COG0436	Aminotransferase
AOD63_RS20680	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AOD63_RS20700	COG2199	diguanylate cyclase activity
AOD63_RS20705	COG0778	Nitroreductase
AOD63_RS20730	COG1263	PTS System
AOD63_RS20730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD63_RS20730	COG2190	(PTS) system
AOD63_RS20735	COG3711	transcriptional antiterminator
AOD63_RS20745	COG2188	Transcriptional regulator
AOD63_RS20755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOD63_RS20785	COG1547	Domain of unknown function (DUF309)
AOD63_RS20790	COG0456	acetyltransferase
AOD63_RS20800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOD63_RS20805	COG4086	secreted protein
AOD63_RS20810	COG0561	phosphatase activity
AOD63_RS20815	COG0697	spore germination
AOD63_RS20830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD63_RS20855	COG0733	neurotransmitter:sodium symporter activity
AOD63_RS20875	COG1686	Belongs to the peptidase S11 family
AOD63_RS20880	COG1725	Transcriptional regulator
AOD63_RS20885	COG1131	(ABC) transporter
AOD63_RS20905	COG1846	Transcriptional regulator
AOD63_RS20920	COG0598	Magnesium transport protein CorA
AOD63_RS20945	COG4974	Belongs to the 'phage' integrase family
AOD63_RS20955	COG0735	belongs to the Fur family
AOD63_RS20960	COG1300	Membrane
AOD63_RS20980	COG0667	Aldo Keto reductase
AOD63_RS20985	COG0656	L-ascorbic acid biosynthetic process
AOD63_RS20990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD63_RS20990	COG0456	acetyltransferase
AOD63_RS21000	COG4085	toxin activity
AOD63_RS21000	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS21000	COG1525	nuclease
AOD63_RS21010	COG0596	Alpha beta hydrolase
AOD63_RS21015	COG2056	Na+-H+ antiporter family
AOD63_RS21020	COG1609	Transcriptional regulator
AOD63_RS21025	COG0456	acetyltransferase
AOD63_RS21030	COG1073	alpha beta
AOD63_RS21045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOD63_RS21045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOD63_RS21050	COG0307	riboflavin synthase, alpha
AOD63_RS21075	COG4106	trans-aconitate 2-methyltransferase activity
AOD63_RS21080	COG2226	methyltransferase
AOD63_RS21080	COG1073	alpha beta
AOD63_RS21095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOD63_RS21105	COG1757	Na H antiporter
AOD63_RS21110	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS21120	COG1522	sequence-specific DNA binding
AOD63_RS21140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOD63_RS21150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOD63_RS21165	COG0300	oxidoreductase activity
AOD63_RS21170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS21180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD63_RS21185	COG1760	l-serine dehydratase
AOD63_RS21190	COG1760	l-serine dehydratase
AOD63_RS21210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOD63_RS21220	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOD63_RS21225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS21240	COG1376	ErfK ybiS ycfS ynhG family protein
AOD63_RS21245	COG4129	membrane
AOD63_RS21250	COG1126	abc transporter atp-binding protein
AOD63_RS21255	COG0765	amino acid transport
AOD63_RS21260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD63_RS21275	COG2816	NAD+ diphosphatase activity
AOD63_RS21280	COG0772	Belongs to the SEDS family
AOD63_RS21290	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD63_RS21295	COG0022	dehydrogenase e1 component
AOD63_RS21300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOD63_RS21305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOD63_RS21320	COG0280	phosphate acetyltransferase
AOD63_RS21330	COG3290	protein histidine kinase activity
AOD63_RS21330	COG3829	transcription factor binding
AOD63_RS21340	COG0584	glycerophosphoryl diester phosphodiesterase
AOD63_RS21345	COG3093	addiction module antidote protein HigA
AOD63_RS21355	COG0745	RESPONSE REGULATOR receiver
AOD63_RS21365	COG0750	zinc metalloprotease
AOD63_RS21370	COG0497	DNA recombination
AOD63_RS21380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AOD63_RS21390	COG0142	geranyltranstransferase activity
AOD63_RS21415	COG1302	Protein conserved in bacteria
AOD63_RS21420	COG0439	Biotin carboxylase
AOD63_RS21425	COG0511	ligase activity, forming carbon-carbon bonds
AOD63_RS21470	COG3854	ATPases associated with a variety of cellular activities
AOD63_RS21495	COG0006	proline dipeptidase activity
AOD63_RS21510	COG3872	metal-dependent enzyme
AOD63_RS21520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOD63_RS21540	COG0095	Lipoate-protein ligase
AOD63_RS21545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD63_RS21550	COG1609	Transcriptional regulator
AOD63_RS21560	COG2076	Multidrug Resistance protein
AOD63_RS21565	COG2076	Multidrug Resistance protein
AOD63_RS21605	COG1131	(ABC) transporter
AOD63_RS21610	COG1725	Transcriptional regulator
AOD63_RS21640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOD63_RS21695	COG4970	Tfp pilus assembly protein FimT
AOD63_RS21705	COG1459	type II secretion system
AOD63_RS21710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOD63_RS21760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOD63_RS21765	COG0646	methionine synthase
AOD63_RS21765	COG1410	methionine synthase
AOD63_RS21770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOD63_RS21770	COG0646	methionine synthase
AOD63_RS21775	COG0626	cystathionine gamma-synthase activity
AOD63_RS21780	COG0626	cystathionine gamma-synthase activity
AOD63_RS21805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS21815	COG1940	carbohydrate kinase activity
AOD63_RS21820	COG4483	Protein conserved in bacteria
AOD63_RS21825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOD63_RS21830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOD63_RS21835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOD63_RS21840	COG0704	Plays a role in the regulation of phosphate uptake
AOD63_RS21850	COG0581	inorganic phosphate transmembrane transporter activity
AOD63_RS21855	COG0573	inorganic phosphate transmembrane transporter activity
AOD63_RS21860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOD63_RS21865	COG0768	penicillin binding
AOD63_RS21870	COG0477	Major facilitator Superfamily
AOD63_RS21875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOD63_RS21900	COG0735	belongs to the Fur family
AOD63_RS21905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOD63_RS21910	COG1121	(ABC) transporter
AOD63_RS21915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS21945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOD63_RS21950	COG2384	SAM-dependent methyltransferase
AOD63_RS21955	COG2010	Cytochrome c
AOD63_RS21960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOD63_RS21965	COG0358	DNA primase activity
AOD63_RS21985	COG0517	IMP dehydrogenase activity
AOD63_RS22000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOD63_RS22005	COG0295	cytidine deaminase activity
AOD63_RS22010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOD63_RS22020	COG1480	7TM receptor with intracellular HD hydrolase
AOD63_RS22025	COG1702	phosphate starvation-inducible protein PhoH
AOD63_RS22045	COG1610	YqeY-like protein
AOD63_RS22050	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOD63_RS22055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOD63_RS22060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOD63_RS22090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOD63_RS22095	COG1733	regulation of RNA biosynthetic process
AOD63_RS22120	COG1466	dna polymerase III delta subunit
AOD63_RS22130	COG0658	competence protein
AOD63_RS22130	COG2333	competence protein COMEC
AOD63_RS22135	COG2131	deaminase
AOD63_RS22140	COG1596	polysaccharide export
AOD63_RS22140	COG1555	photosystem II stabilization
AOD63_RS22145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD63_RS22150	COG2226	methyltransferase
AOD63_RS22155	COG0799	negative regulation of ribosome biogenesis
AOD63_RS22160	COG1713	HD superfamily hydrolase involved in NAD metabolism
AOD63_RS22170	COG1534	Rna-binding protein
AOD63_RS22180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AOD63_RS22185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AOD63_RS22210	COG1595	DNA-templated transcription, initiation
AOD63_RS22220	COG0778	Nitroreductase
AOD63_RS22225	COG2357	RelA SpoT domain protein
AOD63_RS22235	COG1785	Belongs to the alkaline phosphatase family
AOD63_RS22245	COG2267	carboxylic ester hydrolase activity
AOD63_RS22280	COG1404	Belongs to the peptidase S8 family
AOD63_RS22285	COG3186	Phenylalanine-4-hydroxylase
AOD63_RS22295	COG2514	catechol 2,3-dioxygenase activity
AOD63_RS22300	COG2514	catechol 2,3-dioxygenase activity
AOD63_RS22305	COG2259	Doxx family
AOD63_RS22345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS22355	COG1012	belongs to the aldehyde dehydrogenase family
AOD63_RS22355	COG1454	alcohol dehydrogenase
AOD63_RS22360	COG0626	cystathionine gamma-synthase activity
AOD63_RS22365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOD63_RS22390	COG0768	penicillin binding
AOD63_RS22405	COG0826	peptidase U32
AOD63_RS22410	COG0826	peptidase U32
AOD63_RS22415	COG4122	O-methyltransferase activity
AOD63_RS22420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOD63_RS22440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOD63_RS22450	COG0628	permease
AOD63_RS22470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOD63_RS22480	COG0482	sulfurtransferase activity
AOD63_RS22485	COG1104	cysteine desulfurase activity
AOD63_RS22490	COG1959	2 iron, 2 sulfur cluster binding
AOD63_RS22495	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOD63_RS22505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOD63_RS22530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOD63_RS22540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOD63_RS22540	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AOD63_RS22545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AOD63_RS22550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOD63_RS22550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOD63_RS22560	COG2244	polysaccharide biosynthetic process
AOD63_RS22565	COG2323	membrane
AOD63_RS22575	COG1862	Preprotein translocase
AOD63_RS22605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AOD63_RS22615	COG0697	spore germination
AOD63_RS22620	COG0697	spore germination
AOD63_RS22625	COG0640	Transcriptional regulator
AOD63_RS22650	COG0157	Belongs to the NadC ModD family
AOD63_RS22655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOD63_RS22660	COG1104	cysteine desulfurase activity
AOD63_RS22665	COG1827	regulation of RNA biosynthetic process
AOD63_RS22670	COG2258	MOSC domain
AOD63_RS22675	COG0077	Prephenate dehydratase
AOD63_RS22680	COG0577	efflux transmembrane transporter activity
AOD63_RS22685	COG0577	efflux transmembrane transporter activity
AOD63_RS22690	COG1136	(ABC) transporter
AOD63_RS22695	COG5002	protein histidine kinase activity
AOD63_RS22705	COG0745	RESPONSE REGULATOR receiver
AOD63_RS22710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOD63_RS22715	COG3290	protein histidine kinase activity
AOD63_RS22725	COG2868	ribosomal protein
AOD63_RS22735	COG1530	ribonuclease E activity
AOD63_RS22740	COG1994	Peptidase M50
AOD63_RS22745	COG0739	heme binding
AOD63_RS22750	COG2894	cell division
AOD63_RS22770	COG1077	Cell shape determining protein MreB Mrl
AOD63_RS22790	COG0285	dihydrofolate synthase activity
AOD63_RS22795	COG0525	valine-tRNA ligase activity
AOD63_RS22805	COG1388	LysM domain
AOD63_RS22815	COG0113	porphobilinogen synthase activity
AOD63_RS22820	COG1587	Uroporphyrinogen-III synthase
AOD63_RS22830	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOD63_RS22840	COG1846	Transcriptional regulator
AOD63_RS22845	COG1764	response to oxidative stress
AOD63_RS22860	COG0470	DNA polymerase III
AOD63_RS22860	COG1067	ATP-dependent peptidase activity
AOD63_RS22915	COG0622	Phosphoesterase
AOD63_RS22930	COG5401	PFAM Sporulation and spore germination
AOD63_RS22950	COG1309	transcriptional regulator
AOD63_RS22965	COG2197	response regulator
AOD63_RS22970	COG2233	PERMEase
AOD63_RS22980	COG0402	S-adenosylhomocysteine deaminase activity
AOD63_RS22985	COG0402	S-adenosylhomocysteine deaminase activity
AOD63_RS22995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD63_RS23005	COG0444	Belongs to the ABC transporter superfamily
AOD63_RS23010	COG4608	Belongs to the ABC transporter superfamily
AOD63_RS23015	COG3275	phosphorelay sensor kinase activity
AOD63_RS23020	COG3279	Response regulator of the LytR AlgR family
AOD63_RS23035	COG1983	PspC domain protein
AOD63_RS23040	COG1396	sequence-specific DNA binding
AOD63_RS23045	COG0697	spore germination
AOD63_RS23055	COG1959	2 iron, 2 sulfur cluster binding
AOD63_RS23060	COG1668	transmembrane transport
AOD63_RS23065	COG4152	abc transporter atp-binding protein
AOD63_RS23070	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AOD63_RS23080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOD63_RS23085	COG1876	peptidase activity
AOD63_RS23090	COG0824	Thioesterase
AOD63_RS23095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOD63_RS23100	COG1053	succinate dehydrogenase
AOD63_RS23105	COG2009	succinate dehydrogenase
AOD63_RS23110	COG1719	4-vinyl reductase, 4VR
AOD63_RS23120	COG3118	belongs to the thioredoxin family
AOD63_RS23125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOD63_RS23130	COG2086	electron transfer activity
AOD63_RS23135	COG1024	Enoyl-CoA hydratase
AOD63_RS23140	COG1309	transcriptional regulator
AOD63_RS23145	COG0318	PFAM AMP-dependent synthetase and ligase
AOD63_RS23165	COG2318	DinB family
AOD63_RS23195	COG1131	(ABC) transporter
AOD63_RS23200	COG2205	protein histidine kinase activity
AOD63_RS23205	COG0745	RESPONSE REGULATOR receiver
AOD63_RS23215	COG4895	conserved protein (DUF2196)
AOD63_RS23220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AOD63_RS23235	COG4509	Sortase family
AOD63_RS23240	COG1120	ATPase activity
AOD63_RS23255	COG5386	Cell surface protein
AOD63_RS23265	COG5386	Cell surface protein
AOD63_RS23270	COG1114	Component of the transport system for branched-chain amino acids
AOD63_RS23275	COG1187	pseudouridine synthase activity
AOD63_RS23290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOD63_RS23290	COG1796	DNA polymerase
AOD63_RS23295	COG1286	toxin biosynthetic process
AOD63_RS23340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOD63_RS23350	COG1418	mRNA catabolic process
AOD63_RS23375	COG2814	Major facilitator Superfamily
AOD63_RS23380	COG1566	PFAM secretion protein HlyD family protein
AOD63_RS23385	COG1309	transcriptional regulator
AOD63_RS23390	COG1363	Peptidase, m42
AOD63_RS23415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOD63_RS23425	COG1484	DNA-dependent DNA replication
AOD63_RS23430	COG3611	Membrane attachment protein
AOD63_RS23440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AOD63_RS23445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOD63_RS23450	COG0237	dephospho-CoA kinase activity
AOD63_RS23455	COG1971	Probably functions as a manganese efflux pump
AOD63_RS23465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOD63_RS23465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOD63_RS23470	COG5002	protein histidine kinase activity
AOD63_RS23475	COG0745	RESPONSE REGULATOR receiver
AOD63_RS23495	COG0538	isocitrate dehydrogenase activity
AOD63_RS23500	COG0372	Belongs to the citrate synthase family
AOD63_RS23515	COG0628	permease
AOD63_RS23520	COG3030	protein affecting phage T7 exclusion by the F plasmid
AOD63_RS23545	COG1725	Transcriptional regulator
AOD63_RS23550	COG0281	malic enzyme
AOD63_RS23555	COG0587	DNA-directed DNA polymerase activity
AOD63_RS23570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AOD63_RS23590	COG4109	DRTGG domain
AOD63_RS23605	COG0006	proline dipeptidase activity
AOD63_RS23640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS23645	COG0662	Cupin 2, conserved barrel domain protein
AOD63_RS23655	COG1476	TRANSCRIPTIONal
AOD63_RS23670	COG1028	Short-chain dehydrogenase reductase Sdr
AOD63_RS23675	COG0589	response to stress
AOD63_RS23715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS23735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOD63_RS23740	COG0827	DNA restriction-modification system
AOD63_RS23745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AOD63_RS23750	COG3874	Sporulation protein YtfJ
AOD63_RS23765	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOD63_RS23775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOD63_RS23790	COG1104	cysteine desulfurase activity
AOD63_RS23800	COG0583	DNA-binding transcription factor activity
AOD63_RS23805	COG0697	spore germination
AOD63_RS23815	COG1956	GAF domain-containing protein
AOD63_RS23820	COG0626	cystathionine gamma-synthase activity
AOD63_RS23850	COG1595	DNA-templated transcription, initiation
AOD63_RS23860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOD63_RS23865	COG0454	-acetyltransferase
AOD63_RS23870	COG0517	IMP dehydrogenase activity
AOD63_RS23875	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOD63_RS23885	COG0745	RESPONSE REGULATOR receiver
AOD63_RS23895	COG0666	response to abiotic stimulus
AOD63_RS23930	COG1609	Transcriptional regulator
AOD63_RS23940	COG4851	CamS sex pheromone cAM373 precursor
AOD63_RS23945	COG3118	belongs to the thioredoxin family
AOD63_RS23955	COG2309	aminopeptidase activity
AOD63_RS23975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS23990	COG1674	ftsk spoiiie
AOD63_RS24000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD63_RS24005	COG4848	Belongs to the UPF0354 family
AOD63_RS24010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD63_RS24015	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AOD63_RS24020	COG1363	Peptidase, m42
AOD63_RS24030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS24045	COG0510	thiamine kinase activity
AOD63_RS24050	COG1523	belongs to the glycosyl hydrolase 13 family
AOD63_RS24065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD63_RS24070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD63_RS24075	COG1349	DNA-binding transcription factor activity
AOD63_RS24080	COG1187	pseudouridine synthase activity
AOD63_RS24085	COG2244	polysaccharide biosynthetic process
AOD63_RS24090	COG2081	HI0933 family
AOD63_RS24095	COG2814	Major facilitator Superfamily
AOD63_RS24105	COG3832	glyoxalase III activity
AOD63_RS24125	COG1329	Transcriptional regulator
AOD63_RS24135	COG4975	Glucose uptake
AOD63_RS24150	COG0314	molybdopterin synthase activity
AOD63_RS24155	COG1763	Mo-molybdopterin cofactor biosynthetic process
AOD63_RS24160	COG0303	'Molybdopterin
AOD63_RS24170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD63_RS24195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD63_RS24205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOD63_RS24250	COG2814	Major facilitator Superfamily
AOD63_RS24255	COG0475	glutathione-regulated potassium exporter activity
AOD63_RS24260	COG0490	domain, Protein
AOD63_RS24265	COG0582	viral genome integration into host DNA
AOD63_RS24275	COG1136	(ABC) transporter
AOD63_RS24295	COG1242	4 iron, 4 sulfur cluster binding
AOD63_RS24300	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AOD63_RS24305	COG1131	(ABC) transporter
AOD63_RS24315	COG1794	racemase activity, acting on amino acids and derivatives
AOD63_RS24335	COG2267	carboxylic ester hydrolase activity
AOD63_RS24340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOD63_RS24345	COG0671	phosphoesterase, PA-phosphatase related
AOD63_RS24350	COG0438	transferase activity, transferring glycosyl groups
AOD63_RS24360	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOD63_RS24415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOD63_RS24420	COG5002	protein histidine kinase activity
AOD63_RS24425	COG4191	Histidine kinase
AOD63_RS24430	COG2267	carboxylic ester hydrolase activity
AOD63_RS24450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOD63_RS24455	COG1116	anion transmembrane transporter activity
AOD63_RS24460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD63_RS24485	COG0494	nUDIX hydrolase
AOD63_RS24515	COG0288	reversible hydration of carbon dioxide
AOD63_RS24520	COG1271	oxidase subunit
AOD63_RS24525	COG1294	oxidase, subunit
AOD63_RS24545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS24570	COG1842	Phage shock protein A
AOD63_RS24605	COG5002	protein histidine kinase activity
AOD63_RS24610	COG0745	RESPONSE REGULATOR receiver
AOD63_RS24640	COG1597	lipid kinase activity
AOD63_RS24675	COG0586	Pfam SNARE associated Golgi protein
AOD63_RS24685	COG0577	efflux transmembrane transporter activity
AOD63_RS24690	COG1136	(ABC) transporter
AOD63_RS24695	COG3708	Transcriptional regulator
AOD63_RS24695	COG2207	Transcriptional regulator
AOD63_RS24700	COG0745	RESPONSE REGULATOR receiver
AOD63_RS24705	COG2205	protein histidine kinase activity
AOD63_RS24710	COG0577	efflux transmembrane transporter activity
AOD63_RS24720	COG0577	efflux transmembrane transporter activity
AOD63_RS24725	COG1136	(ABC) transporter
AOD63_RS24745	COG2188	Transcriptional regulator
AOD63_RS24765	COG3964	amidohydrolase
AOD63_RS24795	COG4948	Mandelate Racemase Muconate Lactonizing
AOD63_RS24805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOD63_RS24810	COG0596	Alpha beta hydrolase
AOD63_RS24815	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOD63_RS24820	COG1169	isochorismate synthase
AOD63_RS24825	COG1575	Belongs to the MenA family. Type 1 subfamily
AOD63_RS24830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOD63_RS24855	COG0058	SHG alpha-glucan phosphorylase activity
AOD63_RS24860	COG0297	glycogen (starch) synthase activity
AOD63_RS24865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOD63_RS24975	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOD63_RS25010	COG1285	pathogenesis
AOD63_RS25015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOD63_RS25025	COG0166	Belongs to the GPI family
AOD63_RS25035	COG2155	Conserved Protein
AOD63_RS25040	COG1098	S1 RNA binding domain
AOD63_RS25045	COG0436	Aminotransferase
AOD63_RS25050	COG1522	sequence-specific DNA binding
AOD63_RS25055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOD63_RS25060	COG2267	carboxylic ester hydrolase activity
AOD63_RS25070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOD63_RS25090	COG5018	Exonuclease
AOD63_RS25095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOD63_RS25115	COG2050	protein possibly involved in aromatic compounds catabolism
AOD63_RS25125	COG1268	BioY protein
AOD63_RS25135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOD63_RS25140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOD63_RS25155	COG3584	3D domain protein
AOD63_RS25170	COG1252	NADH dehydrogenase
AOD63_RS25185	COG3708	Transcriptional regulator
AOD63_RS25200	COG1683	Conserved Protein
AOD63_RS25220	COG0316	Belongs to the HesB IscA family
AOD63_RS25235	COG1252	NADH dehydrogenase
AOD63_RS25250	COG0390	transport system, permease component
AOD63_RS25255	COG2824	Alkylphosphonate utilization operon protein PhnA
AOD63_RS25295	COG4837	Protein of unknown function (DUF1462)
AOD63_RS25300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AOD63_RS25310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOD63_RS25315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOD63_RS25330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOD63_RS25335	COG0647	UMP catabolic process
AOD63_RS25345	COG2445	Protein of unknown function DUF86
AOD63_RS25350	COG1494	fructose-1,6-bisphosphatase
AOD63_RS25370	COG4470	Protein conserved in bacteria
AOD63_RS25380	COG0789	Transcriptional regulator
AOD63_RS25385	COG4377	Putative membrane peptidase family (DUF2324)
AOD63_RS25410	COG0739	heme binding
AOD63_RS25420	COG3377	Domain of unknown function (DUF1805)
AOD63_RS25425	COG0737	Belongs to the 5'-nucleotidase family
AOD63_RS25435	COG1695	Transcriptional regulator
AOD63_RS25450	COG0719	Fe-S assembly protein
AOD63_RS25455	COG0822	iron-sulfur transferase activity
AOD63_RS25460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOD63_RS25465	COG0719	Fe-S assembly protein
AOD63_RS25470	COG0396	ATPase activity
AOD63_RS25475	COG1464	Belongs to the NlpA lipoprotein family
AOD63_RS25480	COG1464	Belongs to the NlpA lipoprotein family
AOD63_RS25485	COG2011	ABC-type metal ion transport system permease component
AOD63_RS25490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOD63_RS25505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD63_RS25510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AOD63_RS25520	COG1393	Belongs to the ArsC family
AOD63_RS25570	COG0039	L-malate dehydrogenase activity
AOD63_RS25590	COG1309	transcriptional regulator
AOD63_RS25595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD63_RS25600	COG1960	acyl-CoA dehydrogenase activity
AOD63_RS25605	COG0183	Belongs to the thiolase family
AOD63_RS25610	COG1024	Enoyl-CoA hydratase
AOD63_RS25610	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOD63_RS25620	COG1686	Belongs to the peptidase S11 family
AOD63_RS25635	COG0011	TIGRFAM Protein of
AOD63_RS25640	COG0840	transmembrane signaling receptor activity
AOD63_RS25660	COG2814	Major facilitator Superfamily
AOD63_RS25665	COG0531	amino acid
AOD63_RS25675	COG0706	membrane insertase activity
AOD63_RS25685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD63_RS25720	COG0586	Pfam SNARE associated Golgi protein
AOD63_RS25730	COG1376	ErfK ybiS ycfS ynhG family protein
AOD63_RS25735	COG0745	RESPONSE REGULATOR receiver
AOD63_RS25740	COG5002	protein histidine kinase activity
AOD63_RS25765	COG2151	metal-sulfur cluster biosynthetic enzyme
AOD63_RS25770	COG3227	Zinc metalloprotease (Elastase)
AOD63_RS25775	COG1741	Belongs to the pirin family
AOD63_RS25790	COG0475	glutathione-regulated potassium exporter activity
AOD63_RS25795	COG0490	domain, Protein
AOD63_RS25805	COG1115	amino acid carrier protein
AOD63_RS25810	COG0783	Belongs to the Dps family
AOD63_RS25825	COG1611	Belongs to the LOG family
AOD63_RS25840	COG2311	Membrane
AOD63_RS25850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS25855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS25860	COG1115	amino acid carrier protein
AOD63_RS25865	COG1115	amino acid carrier protein
AOD63_RS25870	COG2910	NAD(P)H-binding
AOD63_RS25885	COG0656	L-ascorbic acid biosynthetic process
AOD63_RS25890	COG2814	Major facilitator Superfamily
AOD63_RS25895	COG1733	regulation of RNA biosynthetic process
AOD63_RS25905	COG1252	NADH dehydrogenase
AOD63_RS25910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOD63_RS25915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOD63_RS25925	COG3290	protein histidine kinase activity
AOD63_RS25925	COG0840	transmembrane signaling receptor activity
AOD63_RS25935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOD63_RS25940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOD63_RS25955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD63_RS26010	COG0557	exoribonuclease II activity
AOD63_RS26015	COG1647	Serine aminopeptidase, S33
AOD63_RS26020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOD63_RS26025	COG1346	cytolysis
AOD63_RS26125	COG4695	Portal protein
AOD63_RS26150	COG4974	Belongs to the 'phage' integrase family
AOD63_RS26160	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOD63_RS26165	COG0149	triose-phosphate isomerase activity
AOD63_RS26175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOD63_RS26190	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AOD63_RS26215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD63_RS26230	COG2323	membrane
AOD63_RS26235	COG0740	serine-type endopeptidase activity
AOD63_RS26240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOD63_RS26250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOD63_RS26260	COG1051	belongs to the nudix hydrolase family
AOD63_RS26270	COG0492	ferredoxin-NADP+ reductase activity
AOD63_RS26275	COG0457	Tetratricopeptide repeat
AOD63_RS26280	COG0110	maltose O-acetyltransferase activity
AOD63_RS26300	COG1950	PFAM Membrane protein of
AOD63_RS26310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOD63_RS26315	COG0556	nucleotide-excision repair
AOD63_RS26335	COG0789	Transcriptional regulator
AOD63_RS26360	COG2855	membrane
AOD63_RS26365	COG0583	DNA-binding transcription factor activity
AOD63_RS26375	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOD63_RS26380	COG0488	(ABC) transporter
AOD63_RS26390	COG1132	(ABC) transporter
AOD63_RS26395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOD63_RS26400	COG3409	Peptidoglycan-binding domain 1 protein
AOD63_RS26400	COG0793	Belongs to the peptidase S41A family
AOD63_RS26405	COG2177	Part of the ABC transporter FtsEX involved in
AOD63_RS26410	COG2884	Cell division ATP-binding protein ftsE
AOD63_RS26425	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOD63_RS26430	COG0653	protein targeting
AOD63_RS26435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOD63_RS26440	COG1278	Cold shock
AOD63_RS26445	COG1040	competence protein
AOD63_RS26450	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AOD63_RS26455	COG0791	NLP P60 protein
AOD63_RS26455	COG1388	LysM domain
AOD63_RS26460	COG1733	regulation of RNA biosynthetic process
AOD63_RS26470	COG1307	EDD domain protein, DegV family
AOD63_RS26475	COG1739	Uncharacterized protein family UPF0029
AOD63_RS26480	COG1316	TRANSCRIPTIONal
AOD63_RS26485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AOD63_RS26490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOD63_RS26495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOD63_RS26505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AOD63_RS26505	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AOD63_RS26520	COG3394	polysaccharide catabolic process
AOD63_RS26525	COG1486	melibiose metabolic process
AOD63_RS26530	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOD63_RS26535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOD63_RS26545	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AOD63_RS26550	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AOD63_RS26555	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOD63_RS26565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOD63_RS26570	COG1301	dicarboxylic acid transport
AOD63_RS26580	COG0346	lactoylglutathione lyase activity
AOD63_RS26585	COG1511	domain protein
AOD63_RS26590	COG0583	DNA-binding transcription factor activity
AOD63_RS26595	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AOD63_RS26615	COG1271	oxidase subunit
AOD63_RS26620	COG1294	oxidase, subunit
AOD63_RS26625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOD63_RS26635	COG1620	l-lactate permease
AOD63_RS26645	COG2389	metal-binding protein
AOD63_RS26655	COG1368	sulfuric ester hydrolase activity
AOD63_RS26670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD63_RS26690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOD63_RS26695	COG1388	LysM domain
AOD63_RS26695	COG3584	3D domain protein
AOD63_RS26720	COG4715	Zinc finger, swim domain protein
AOD63_RS26725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOD63_RS26765	COG0577	efflux transmembrane transporter activity
AOD63_RS26770	COG1136	(ABC) transporter
AOD63_RS26805	COG5002	protein histidine kinase activity
AOD63_RS26810	COG0745	RESPONSE REGULATOR receiver
AOD63_RS26815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOD63_RS26830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AOD63_RS26835	COG1134	teichoic acid transport
AOD63_RS26840	COG1682	transport, permease protein
AOD63_RS26845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOD63_RS26890	COG1609	Transcriptional regulator
AOD63_RS26905	COG0739	heme binding
AOD63_RS26920	COG3279	Response regulator of the LytR AlgR family
AOD63_RS26925	COG4555	ABC transporter
AOD63_RS26930	COG2385	sporulation resulting in formation of a cellular spore
AOD63_RS26945	COG4836	Membrane
AOD63_RS26950	COG1007	ATP synthesis coupled electron transport
AOD63_RS26955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOD63_RS26960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOD63_RS26970	COG0839	Belongs to the complex I subunit 6 family
AOD63_RS26985	COG0649	NAD binding
AOD63_RS26990	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOD63_RS27005	COG3300	MHYT domain
AOD63_RS27005	COG5001	Diguanylate cyclase
AOD63_RS27055	COG0356	it plays a direct role in the translocation of protons across the membrane
AOD63_RS27090	COG0698	ribose 5-phosphate isomerase
AOD63_RS27100	COG2190	(PTS) system
AOD63_RS27105	COG2259	Doxx family
AOD63_RS27110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOD63_RS27125	COG0009	L-threonylcarbamoyladenylate synthase
AOD63_RS27140	COG2890	protein-(glutamine-N5) methyltransferase activity
AOD63_RS27160	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOD63_RS27165	COG1494	fructose-1,6-bisphosphatase
AOD63_RS27185	COG4821	SIS domain
AOD63_RS27195	COG3343	RNA polymerase activity
AOD63_RS27205	COG1960	acyl-CoA dehydrogenase activity
AOD63_RS27210	COG1960	acyl-CoA dehydrogenase activity
AOD63_RS27215	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOD63_RS27220	COG0183	Belongs to the thiolase family
AOD63_RS27225	COG2181	nitrate reductase activity
AOD63_RS27225	COG0247	lactate metabolic process
AOD63_RS27230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD63_RS27240	COG3300	MHYT domain
AOD63_RS27240	COG5001	Diguanylate cyclase
AOD63_RS27255	COG2197	response regulator
AOD63_RS27260	COG4585	Histidine kinase
AOD63_RS27265	COG0842	Transport permease protein
AOD63_RS27270	COG1131	(ABC) transporter
AOD63_RS27275	COG0024	Methionine aminopeptidase
AOD63_RS27295	COG2234	aminopeptidase activity
AOD63_RS27315	COG1595	DNA-templated transcription, initiation
AOD63_RS27320	COG0018	arginyl-trna synthetase
AOD63_RS27325	COG4506	Protein conserved in bacteria
AOD63_RS27330	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOD63_RS27345	COG0010	Belongs to the arginase family
AOD63_RS27355	COG2814	Major facilitator Superfamily
AOD63_RS27360	COG0789	Transcriptional regulator
AOD63_RS27365	COG0584	glycerophosphoryl diester phosphodiesterase
AOD63_RS27370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD63_RS27380	COG1994	Peptidase M50
AOD63_RS27390	COG1078	dGTPase activity
AOD63_RS27395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD63_RS27400	COG1120	ATPase activity
AOD63_RS27405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS27410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS27415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD63_RS27435	COG0095	Lipoate-protein ligase
AOD63_RS27440	COG0280	phosphate acetyltransferase
AOD63_RS27455	COG3773	Cell wall hydrolase
AOD63_RS27465	COG2363	Small membrane protein
AOD63_RS27480	COG2233	PERMEase
AOD63_RS27485	COG0561	phosphatase activity
AOD63_RS27490	COG2814	Major facilitator Superfamily
AOD63_RS27500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AOD63_RS27505	COG1131	(ABC) transporter
AOD63_RS27510	COG2755	lipolytic protein G-D-S-L family
AOD63_RS27515	COG1609	Transcriptional regulator
AOD63_RS27525	COG0460	homoserine dehydrogenase
AOD63_RS27535	COG2873	o-acetylhomoserine
AOD63_RS27545	COG1011	Hydrolase
AOD63_RS27550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOD63_RS27560	COG2197	response regulator
AOD63_RS27570	COG0351	phosphomethylpyrimidine kinase
AOD63_RS27575	COG3706	GGDEF domain
AOD63_RS27580	COG2879	small protein
AOD63_RS27585	COG1966	Carbon starvation protein
AOD63_RS27590	COG3279	Response regulator of the LytR AlgR family
AOD63_RS27595	COG0477	Major facilitator Superfamily
AOD63_RS27620	COG0840	transmembrane signaling receptor activity
AOD63_RS27630	COG1607	acyl-coa hydrolase
AOD63_RS27645	COG0488	(ABC) transporter
AOD63_RS27675	COG0463	Glycosyl transferase, family 2
AOD63_RS27680	COG1309	transcriptional regulator
AOD63_RS27685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOD63_RS27690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOD63_RS27690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOD63_RS27695	COG0628	permease
AOD63_RS27710	COG3279	Response regulator of the LytR AlgR family
AOD63_RS27715	COG3275	phosphorelay sensor kinase activity
AOD63_RS27720	COG2814	Major facilitator Superfamily
AOD63_RS27725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOD63_RS27730	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOD63_RS27740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOD63_RS27760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOD63_RS27765	COG1272	protein, Hemolysin III
AOD63_RS27785	COG0516	GMP reductase activity
AOD63_RS27790	COG1164	Oligoendopeptidase f
AOD63_RS27810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOD63_RS27815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOD63_RS27820	COG4853	Protein conserved in bacteria
AOD63_RS27825	COG4863	YycH protein
AOD63_RS27830	COG5002	protein histidine kinase activity
AOD63_RS27835	COG0745	RESPONSE REGULATOR receiver
AOD63_RS27865	COG0305	Participates in initiation and elongation during chromosome replication
AOD63_RS27875	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AOD63_RS27880	COG4241	membrane
AOD63_RS27890	COG0629	single-stranded DNA binding
AOD63_RS27900	COG0012	GTP binding
AOD63_RS27905	COG4481	Protein conserved in bacteria
AOD63_RS27910	COG0668	transmembrane transport
AOD63_RS27920	COG1475	DNA binding
AOD63_RS27925	COG1192	Involved in chromosome partitioning
AOD63_RS27950	COG1847	R3H domain protein
AOD63_RS27955	COG0706	membrane insertase activity
AOD63_RS27965	COG0230	Belongs to the bacterial ribosomal protein bL34 family