locus-tag	class	description
AOD64_RS00010	COG0592	DNA-directed DNA polymerase activity
AOD64_RS00015	COG2501	S4 domain
AOD64_RS00025	COG0187	DNA topoisomerase II activity
AOD64_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOD64_RS00065	COG0517	IMP dehydrogenase activity
AOD64_RS00065	COG0516	GMP reductase activity
AOD64_RS00070	COG1686	Belongs to the peptidase S11 family
AOD64_RS00100	COG1428	Deoxynucleoside kinase
AOD64_RS00105	COG1428	Deoxynucleoside kinase
AOD64_RS00110	COG1335	isochorismatase
AOD64_RS00120	COG0590	tRNA wobble adenosine to inosine editing
AOD64_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOD64_RS00185	COG1982	Orn Lys Arg decarboxylase major
AOD64_RS00195	COG0470	DNA polymerase III
AOD64_RS00200	COG1774	PSP1 C-terminal conserved region
AOD64_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AOD64_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AOD64_RS00225	COG2002	toxin-antitoxin pair type II binding
AOD64_RS00230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD64_RS00230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD64_RS00235	COG0084	hydrolase, TatD family'
AOD64_RS00240	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AOD64_RS00255	COG4466	Protein conserved in bacteria
AOD64_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AOD64_RS00275	COG0251	oxidation-reduction process
AOD64_RS00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOD64_RS00310	COG2002	toxin-antitoxin pair type II binding
AOD64_RS00315	COG2244	polysaccharide biosynthetic process
AOD64_RS00320	COG3956	TIGRFAM MazG family protein
AOD64_RS00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOD64_RS00345	COG1098	S1 RNA binding domain
AOD64_RS00360	COG2208	phosphoserine phosphatase activity
AOD64_RS00365	COG0037	tRNA processing
AOD64_RS00370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AOD64_RS00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOD64_RS00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOD64_RS00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOD64_RS00400	COG0512	Glutamine amidotransferase of anthranilate synthase
AOD64_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD64_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOD64_RS00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AOD64_RS00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOD64_RS00425	COG1396	sequence-specific DNA binding
AOD64_RS00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOD64_RS00460	COG3880	PFAM UvrB UvrC protein
AOD64_RS00470	COG0542	response to heat
AOD64_RS00475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AOD64_RS00485	COG4956	integral membrane protein (PIN domain superfamily)
AOD64_RS00505	COG1045	serine acetyltransferase
AOD64_RS00520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOD64_RS00525	COG3688	RNA-binding protein containing a PIN domain
AOD64_RS00540	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOD64_RS00545	COG0250	Participates in transcription elongation, termination and antitermination
AOD64_RS00550	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AOD64_RS00570	COG2813	Specifically methylates the guanine in position
AOD64_RS00580	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AOD64_RS00585	COG1358	cellular component organization or biogenesis
AOD64_RS00655	COG0255	Belongs to the universal ribosomal protein uL29 family
AOD64_RS00715	COG0201	protein transport
AOD64_RS00725	COG0024	Methionine aminopeptidase
AOD64_RS00735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AOD64_RS00770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOD64_RS00795	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS00800	COG0489	protein tyrosine kinase activity
AOD64_RS00810	COG2194	sulfuric ester hydrolase activity
AOD64_RS00815	COG0726	polysaccharide deacetylase
AOD64_RS00900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AOD64_RS00905	COG4856	YbbR-like protein
AOD64_RS00920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOD64_RS00925	COG0596	Alpha beta hydrolase
AOD64_RS00945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AOD64_RS00950	COG4946	Tricorn protease homolog
AOD64_RS00950	COG1506	peptidase
AOD64_RS00950	COG0823	Involved in the tonB-independent uptake of proteins
AOD64_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS00990	COG2011	ABC-type metal ion transport system permease component
AOD64_RS00995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOD64_RS01000	COG1464	Belongs to the NlpA lipoprotein family
AOD64_RS01005	COG0604	alcohol dehydrogenase
AOD64_RS01015	COG0277	FAD linked oxidase domain protein
AOD64_RS01020	COG2271	Major facilitator Superfamily
AOD64_RS01030	COG2814	Major facilitator Superfamily
AOD64_RS01045	COG0601	transmembrane transport
AOD64_RS01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD64_RS01055	COG0444	Belongs to the ABC transporter superfamily
AOD64_RS01060	COG4608	Belongs to the ABC transporter superfamily
AOD64_RS01065	COG4166	transmembrane transport
AOD64_RS01075	COG2207	Transcriptional regulator
AOD64_RS01090	COG4166	transmembrane transport
AOD64_RS01095	COG4166	transmembrane transport
AOD64_RS01100	COG0656	L-ascorbic acid biosynthetic process
AOD64_RS01105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD64_RS01125	COG4149	molybdate abc transporter
AOD64_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOD64_RS01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOD64_RS01140	COG1910	domain protein
AOD64_RS01155	COG0583	DNA-binding transcription factor activity
AOD64_RS01160	COG0697	spore germination
AOD64_RS01175	COG0204	Acyl-transferase
AOD64_RS01190	COG1609	Transcriptional regulator
AOD64_RS01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS01215	COG0084	hydrolase, TatD family'
AOD64_RS01220	COG5298	Protein conserved in bacteria
AOD64_RS01245	COG0488	(ABC) transporter
AOD64_RS01260	COG0747	negative chemotaxis
AOD64_RS01265	COG0601	transmembrane transport
AOD64_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD64_RS01275	COG0444	Belongs to the ABC transporter superfamily
AOD64_RS01280	COG4608	Belongs to the ABC transporter superfamily
AOD64_RS01305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AOD64_RS01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOD64_RS01320	COG2814	Major facilitator Superfamily
AOD64_RS01335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOD64_RS01345	COG4294	response to UV
AOD64_RS01350	COG0457	Tetratricopeptide repeat
AOD64_RS01350	COG0705	Rhomboid family
AOD64_RS01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOD64_RS01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOD64_RS01370	COG0864	Transcriptional regulator
AOD64_RS01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
AOD64_RS01380	COG2183	response to ionizing radiation
AOD64_RS01475	COG0802	atpase or kinase
AOD64_RS01480	COG1214	PFAM Peptidase M22, glycoprotease
AOD64_RS01485	COG0456	acetyltransferase
AOD64_RS01495	COG0488	(ABC) transporter
AOD64_RS01510	COG1266	CAAX protease self-immunity
AOD64_RS01530	COG2252	PERMEase
AOD64_RS01540	COG5002	protein histidine kinase activity
AOD64_RS01570	COG2226	methyltransferase
AOD64_RS01610	COG1968	undecaprenyl-diphosphatase activity
AOD64_RS01625	COG2205	protein histidine kinase activity
AOD64_RS01630	COG0745	RESPONSE REGULATOR receiver
AOD64_RS01650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AOD64_RS01655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOD64_RS01660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOD64_RS01670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOD64_RS01685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AOD64_RS01695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOD64_RS01705	COG0151	Belongs to the GarS family
AOD64_RS01730	COG0210	DNA helicase
AOD64_RS01740	COG4851	CamS sex pheromone cAM373 precursor
AOD64_RS01760	COG1335	isochorismatase
AOD64_RS01765	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOD64_RS01770	COG2011	ABC-type metal ion transport system permease component
AOD64_RS01775	COG1464	Belongs to the NlpA lipoprotein family
AOD64_RS01795	COG1846	Transcriptional regulator
AOD64_RS01820	COG1597	lipid kinase activity
AOD64_RS01825	COG0546	phosphoglycolate phosphatase activity
AOD64_RS01830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOD64_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS01845	COG2076	Multidrug Resistance protein
AOD64_RS01850	COG2309	aminopeptidase activity
AOD64_RS01865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS01870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOD64_RS01875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOD64_RS01885	COG4807	Protein conserved in bacteria
AOD64_RS01910	COG1757	Na H antiporter
AOD64_RS01915	COG1473	amidohydrolase
AOD64_RS01930	COG0450	alkyl hydroperoxide reductase
AOD64_RS01950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS01955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS01960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS01980	COG0166	Belongs to the GPI family
AOD64_RS02015	COG5002	protein histidine kinase activity
AOD64_RS02035	COG3541	Predicted nucleotidyltransferase
AOD64_RS02040	COG2814	Major facilitator Superfamily
AOD64_RS02045	COG0723	plastoquinol--plastocyanin reductase activity
AOD64_RS02045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD64_RS02055	COG0765	amino acid transport
AOD64_RS02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD64_RS02075	COG0840	transmembrane signaling receptor activity
AOD64_RS02080	COG0840	transmembrane signaling receptor activity
AOD64_RS02085	COG0366	Alpha amylase catalytic
AOD64_RS02090	COG2190	(PTS) system
AOD64_RS02090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD64_RS02090	COG1263	PTS System
AOD64_RS02120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AOD64_RS02135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD64_RS02145	COG1116	anion transmembrane transporter activity
AOD64_RS02150	COG0488	(ABC) transporter
AOD64_RS02195	COG2270	Major facilitator Superfamily
AOD64_RS02210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOD64_RS02225	COG2310	stress, protein
AOD64_RS02230	COG2310	stress, protein
AOD64_RS02235	COG2310	stress, protein
AOD64_RS02240	COG0861	Integral membrane protein TerC family
AOD64_RS02250	COG3853	Toxic anion resistance protein (TelA)
AOD64_RS02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOD64_RS02275	COG1295	ribonuclease BN
AOD64_RS02280	COG2217	Heavy metal translocating P-type atpase
AOD64_RS02285	COG0697	spore germination
AOD64_RS02305	COG0586	Pfam SNARE associated Golgi protein
AOD64_RS02320	COG3871	stress protein (general stress protein 26)
AOD64_RS02325	COG0387	Pfam Sodium calcium exchanger
AOD64_RS02335	COG0535	radical SAM domain protein
AOD64_RS02360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOD64_RS02365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AOD64_RS02370	COG0582	viral genome integration into host DNA
AOD64_RS02375	COG1396	sequence-specific DNA binding
AOD64_RS02390	COG1396	sequence-specific DNA binding
AOD64_RS02425	COG1484	DNA-dependent DNA replication
AOD64_RS02520	COG0582	viral genome integration into host DNA
AOD64_RS02525	COG0582	viral genome integration into host DNA
AOD64_RS02650	COG0101	tRNA pseudouridine synthase activity
AOD64_RS02660	COG3829	transcription factor binding
AOD64_RS02670	COG0833	amino acid
AOD64_RS02675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD64_RS02710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD64_RS02710	COG1263	PTS System
AOD64_RS02715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD64_RS02730	COG0463	Glycosyl transferase, family 2
AOD64_RS02745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOD64_RS02745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AOD64_RS02765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AOD64_RS02785	COG1228	amidohydrolase
AOD64_RS02790	COG1090	epimerase
AOD64_RS02820	COG1988	membrane-bound metal-dependent
AOD64_RS02825	COG1194	a g-specific adenine glycosylase
AOD64_RS02850	COG1132	(ABC) transporter
AOD64_RS02855	COG4129	membrane
AOD64_RS02860	COG0070	glutamate synthase
AOD64_RS02860	COG0069	glutamate synthase activity
AOD64_RS02860	COG0067	glutamate synthase
AOD64_RS02870	COG4555	ABC transporter
AOD64_RS02890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOD64_RS02895	COG0735	belongs to the Fur family
AOD64_RS03010	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AOD64_RS03015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOD64_RS03025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOD64_RS03035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOD64_RS03050	COG2766	serine protein kinase
AOD64_RS03075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOD64_RS03085	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOD64_RS03090	COG2268	Band 7 protein
AOD64_RS03100	COG3290	protein histidine kinase activity
AOD64_RS03110	COG2851	Citrate transporter
AOD64_RS03130	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AOD64_RS03135	COG3842	ATPase activity
AOD64_RS03140	COG1175	transmembrane transport
AOD64_RS03145	COG0395	ABC-type sugar transport system, permease component
AOD64_RS03155	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOD64_RS03160	COG0745	RESPONSE REGULATOR receiver
AOD64_RS03165	COG5002	protein histidine kinase activity
AOD64_RS03175	COG4990	cell redox homeostasis
AOD64_RS03185	COG3290	protein histidine kinase activity
AOD64_RS03190	COG4565	transcriptional regulatory protein
AOD64_RS03195	COG3493	citrate carrier protein
AOD64_RS03200	COG0281	malic enzyme
AOD64_RS03215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS03225	COG5002	protein histidine kinase activity
AOD64_RS03230	COG0745	RESPONSE REGULATOR receiver
AOD64_RS03240	COG0456	acetyltransferase
AOD64_RS03240	COG0454	-acetyltransferase
AOD64_RS03245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOD64_RS03250	COG3383	formate dehydrogenase (NAD+) activity
AOD64_RS03255	COG2427	Protein of unknown function (DUF1641)
AOD64_RS03270	COG0531	amino acid
AOD64_RS03275	COG0640	Transcriptional regulator
AOD64_RS03280	COG2217	Heavy metal translocating P-type atpase
AOD64_RS03285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AOD64_RS03295	COG3227	Zinc metalloprotease (Elastase)
AOD64_RS03315	COG2720	vancomycin resistance protein
AOD64_RS03320	COG1316	TRANSCRIPTIONal
AOD64_RS03325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS03330	COG0346	lactoylglutathione lyase activity
AOD64_RS03335	COG1253	flavin adenine dinucleotide binding
AOD64_RS03340	COG1027	Aspartate ammonia-lyase
AOD64_RS03345	COG1620	l-lactate permease
AOD64_RS03360	COG3104	oligopeptide transport
AOD64_RS03365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS03375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS03385	COG2226	methyltransferase
AOD64_RS03390	COG0156	8-amino-7-oxononanoate synthase activity
AOD64_RS03405	COG4548	von Willebrand factor, type A
AOD64_RS03410	COG0714	Associated with various cellular activities
AOD64_RS03415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD64_RS03435	COG0531	amino acid
AOD64_RS03440	COG2188	Transcriptional regulator
AOD64_RS03445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD64_RS03445	COG1263	PTS System
AOD64_RS03450	COG0366	Alpha amylase catalytic
AOD64_RS03465	COG0697	spore germination
AOD64_RS03475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOD64_RS03480	COG1115	amino acid carrier protein
AOD64_RS03485	COG1126	abc transporter atp-binding protein
AOD64_RS03490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD64_RS03495	COG0765	amino acid transport
AOD64_RS03500	COG0765	amino acid transport
AOD64_RS03505	COG0833	amino acid
AOD64_RS03530	COG2378	regulation of single-species biofilm formation
AOD64_RS03535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOD64_RS03540	COG5002	protein histidine kinase activity
AOD64_RS03555	COG0659	secondary active sulfate transmembrane transporter activity
AOD64_RS03570	COG0747	negative chemotaxis
AOD64_RS03580	COG0601	transmembrane transport
AOD64_RS03585	COG4608	Belongs to the ABC transporter superfamily
AOD64_RS03595	COG2271	Major facilitator Superfamily
AOD64_RS03600	COG1846	Transcriptional regulator
AOD64_RS03605	COG0477	Major facilitator Superfamily
AOD64_RS03610	COG0477	Major facilitator Superfamily
AOD64_RS03615	COG1609	Transcriptional regulator
AOD64_RS03620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOD64_RS03635	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOD64_RS03640	COG1879	ABC-type sugar transport system periplasmic component
AOD64_RS03665	COG1063	alcohol dehydrogenase
AOD64_RS03680	COG3568	Endonuclease Exonuclease Phosphatase
AOD64_RS03705	COG1968	undecaprenyl-diphosphatase activity
AOD64_RS03710	COG0840	transmembrane signaling receptor activity
AOD64_RS03715	COG1388	LysM domain
AOD64_RS03715	COG3584	3D domain protein
AOD64_RS03720	COG1476	TRANSCRIPTIONal
AOD64_RS03735	COG3104	oligopeptide transport
AOD64_RS03740	COG1114	Component of the transport system for branched-chain amino acids
AOD64_RS03755	COG1113	amino acid transport
AOD64_RS03760	COG2252	PERMEase
AOD64_RS03785	COG0569	domain protein
AOD64_RS03785	COG0475	glutathione-regulated potassium exporter activity
AOD64_RS03800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOD64_RS03805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOD64_RS03810	COG0833	amino acid
AOD64_RS03815	COG4990	cell redox homeostasis
AOD64_RS03830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD64_RS03835	COG0697	spore germination
AOD64_RS03840	COG0531	amino acid
AOD64_RS03855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOD64_RS03860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOD64_RS03865	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AOD64_RS03865	COG1918	ferrous iron import across plasma membrane
AOD64_RS03870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOD64_RS03875	COG0573	inorganic phosphate transmembrane transporter activity
AOD64_RS03880	COG0581	inorganic phosphate transmembrane transporter activity
AOD64_RS03890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOD64_RS04005	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AOD64_RS04030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOD64_RS04035	COG1116	anion transmembrane transporter activity
AOD64_RS04040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD64_RS04045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOD64_RS04050	COG0352	thiamine-phosphate diphosphorylase activity
AOD64_RS04055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD64_RS04060	COG2104	thiamine diphosphate biosynthetic process
AOD64_RS04070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD64_RS04075	COG0351	phosphomethylpyrimidine kinase
AOD64_RS04115	COG2205	protein histidine kinase activity
AOD64_RS04120	COG2814	Major facilitator Superfamily
AOD64_RS04125	COG1846	Transcriptional regulator
AOD64_RS04140	COG2252	PERMEase
AOD64_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS04160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOD64_RS04165	COG1621	beta-fructofuranosidase activity
AOD64_RS04170	COG1263	PTS System
AOD64_RS04170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD64_RS04175	COG1609	Transcriptional regulator
AOD64_RS04185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD64_RS04190	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AOD64_RS04230	COG0778	Nitroreductase
AOD64_RS04235	COG2719	SpoVR family
AOD64_RS04260	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOD64_RS04265	COG1937	Protein conserved in bacteria
AOD64_RS04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD64_RS04270	COG0425	Belongs to the sulfur carrier protein TusA family
AOD64_RS04275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD64_RS04275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS04280	COG0425	Belongs to the sulfur carrier protein TusA family
AOD64_RS04285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD64_RS04295	COG2210	Belongs to the sulfur carrier protein TusA family
AOD64_RS04300	COG0730	response to heat
AOD64_RS04310	COG1316	TRANSCRIPTIONal
AOD64_RS04315	COG0604	alcohol dehydrogenase
AOD64_RS04320	COG1283	sodium-dependent phosphate transmembrane transporter activity
AOD64_RS04335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOD64_RS04335	COG3711	transcriptional antiterminator
AOD64_RS04340	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOD64_RS04345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOD64_RS04365	COG3584	3D domain protein
AOD64_RS04365	COG1388	LysM domain
AOD64_RS04370	COG0577	efflux transmembrane transporter activity
AOD64_RS04375	COG1136	(ABC) transporter
AOD64_RS04385	COG5522	Integral membrane protein (intg_mem_TP0381)
AOD64_RS04400	COG1114	Component of the transport system for branched-chain amino acids
AOD64_RS04405	COG3546	catalase activity
AOD64_RS04440	COG0586	Pfam SNARE associated Golgi protein
AOD64_RS04475	COG0531	amino acid
AOD64_RS04480	COG0475	glutathione-regulated potassium exporter activity
AOD64_RS04490	COG1737	Transcriptional regulator
AOD64_RS04500	COG1263	PTS System
AOD64_RS04500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD64_RS04510	COG2259	Doxx family
AOD64_RS04525	COG0697	spore germination
AOD64_RS04530	COG1522	sequence-specific DNA binding
AOD64_RS04545	COG2076	Multidrug Resistance protein
AOD64_RS04550	COG1309	transcriptional regulator
AOD64_RS04555	COG2814	Major facilitator Superfamily
AOD64_RS04560	COG1733	regulation of RNA biosynthetic process
AOD64_RS04570	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOD64_RS04575	COG4533	DNA binding
AOD64_RS04580	COG2211	Major facilitator Superfamily
AOD64_RS04590	COG0693	protein deglycase activity
AOD64_RS04595	COG0753	catalase activity
AOD64_RS04605	COG0531	amino acid
AOD64_RS04610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOD64_RS04620	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS04630	COG1132	(ABC) transporter
AOD64_RS04640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD64_RS04645	COG0765	amino acid transport
AOD64_RS04650	COG1126	abc transporter atp-binding protein
AOD64_RS04665	COG0189	ligase activity
AOD64_RS04695	COG0028	Belongs to the TPP enzyme family
AOD64_RS04700	COG3527	Alpha-acetolactate decarboxylase
AOD64_RS04715	COG0561	phosphatase activity
AOD64_RS04730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOD64_RS04745	COG0659	secondary active sulfate transmembrane transporter activity
AOD64_RS04765	COG0653	protein targeting
AOD64_RS04770	COG2244	polysaccharide biosynthetic process
AOD64_RS04780	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS04785	COG4196	transglutaminase domain protein
AOD64_RS04800	COG1696	Membrane protein involved in D-alanine export
AOD64_RS04815	COG1024	Enoyl-CoA hydratase
AOD64_RS04835	COG1363	Peptidase, m42
AOD64_RS04855	COG3938	Belongs to the proline racemase family
AOD64_RS04895	COG0601	transmembrane transport
AOD64_RS04900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD64_RS04910	COG4608	Belongs to the ABC transporter superfamily
AOD64_RS04940	COG0477	Major facilitator Superfamily
AOD64_RS04945	COG3290	protein histidine kinase activity
AOD64_RS04950	COG4565	transcriptional regulatory protein
AOD64_RS04955	COG3181	Tripartite tricarboxylate transporter family receptor
AOD64_RS04985	COG4978	Transcriptional regulator
AOD64_RS04985	COG0789	Transcriptional regulator
AOD64_RS05000	COG0305	Participates in initiation and elongation during chromosome replication
AOD64_RS05040	COG0477	Major facilitator Superfamily
AOD64_RS05090	COG3320	Male sterility
AOD64_RS05090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOD64_RS05095	COG1309	transcriptional regulator
AOD64_RS05115	COG1183	phosphatidylcholine synthase activity
AOD64_RS05135	COG2376	Dihydroxyacetone kinase
AOD64_RS05145	COG2376	Dihydroxyacetone kinase
AOD64_RS05150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOD64_RS05155	COG1959	2 iron, 2 sulfur cluster binding
AOD64_RS05180	COG3437	response regulator, receiver
AOD64_RS05180	COG2770	Histidine kinase
AOD64_RS05230	COG3237	CsbD-like
AOD64_RS05255	COG1191	sigma factor activity
AOD64_RS05265	COG2208	phosphoserine phosphatase activity
AOD64_RS05270	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOD64_RS05275	COG2205	protein histidine kinase activity
AOD64_RS05275	COG0784	Response regulator, receiver
AOD64_RS05275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD64_RS05275	COG2198	Histidine kinase
AOD64_RS05335	COG0420	3'-5' exonuclease activity
AOD64_RS05340	COG4717	serine-type aminopeptidase activity
AOD64_RS05360	COG1309	transcriptional regulator
AOD64_RS05365	COG2814	Major facilitator Superfamily
AOD64_RS05370	COG0346	lactoylglutathione lyase activity
AOD64_RS05375	COG0346	lactoylglutathione lyase activity
AOD64_RS05380	COG0457	Tetratricopeptide repeat
AOD64_RS05385	COG2267	carboxylic ester hydrolase activity
AOD64_RS05405	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AOD64_RS05410	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AOD64_RS05420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AOD64_RS05460	COG0477	Major facilitator Superfamily
AOD64_RS05465	COG0477	Major facilitator Superfamily
AOD64_RS05475	COG3973	AAA domain
AOD64_RS05480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOD64_RS05505	COG4980	gas vesicle protein
AOD64_RS05510	COG0537	adenosine 5'-monophosphoramidase activity
AOD64_RS05515	COG1131	(ABC) transporter
AOD64_RS05520	COG4473	ABC transporter
AOD64_RS05530	COG1309	transcriptional regulator
AOD64_RS05540	COG3402	PFAM membrane-flanked domain
AOD64_RS05550	COG3428	Bacterial PH domain
AOD64_RS05590	COG3402	PFAM membrane-flanked domain
AOD64_RS05595	COG3428	Bacterial PH domain
AOD64_RS05600	COG2329	Antibiotic biosynthesis monooxygenase
AOD64_RS05605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD64_RS05610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AOD64_RS05615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOD64_RS05620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOD64_RS05655	COG1309	transcriptional regulator
AOD64_RS05660	COG1511	domain protein
AOD64_RS05695	COG1234	tRNA 3'-trailer cleavage
AOD64_RS05700	COG0095	Lipoate-protein ligase
AOD64_RS05710	COG0318	PFAM AMP-dependent synthetase and ligase
AOD64_RS05740	COG3209	COG3209 Rhs family protein
AOD64_RS05785	COG1408	metallophosphoesterase
AOD64_RS05790	COG1078	dGTPase activity
AOD64_RS05800	COG1595	DNA-templated transcription, initiation
AOD64_RS05805	COG3708	Transcriptional regulator
AOD64_RS05805	COG2207	Transcriptional regulator
AOD64_RS05820	COG2205	protein histidine kinase activity
AOD64_RS05825	COG0745	RESPONSE REGULATOR receiver
AOD64_RS05850	COG0501	Belongs to the peptidase M48B family
AOD64_RS05855	COG0840	transmembrane signaling receptor activity
AOD64_RS05860	COG0697	spore germination
AOD64_RS05880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOD64_RS05885	COG2224	Isocitrate lyase
AOD64_RS05910	COG4903	ComK protein
AOD64_RS05915	COG0398	Pfam SNARE associated Golgi protein
AOD64_RS05925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AOD64_RS05930	COG1074	ATP-dependent DNA helicase activity
AOD64_RS05975	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOD64_RS06000	COG0367	asparagine synthase
AOD64_RS06005	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AOD64_RS06010	COG0753	catalase activity
AOD64_RS06015	COG0004	ammonium transporteR
AOD64_RS06040	COG2996	Protein conserved in bacteria
AOD64_RS06050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOD64_RS06060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS06075	COG0561	phosphatase activity
AOD64_RS06090	COG0542	response to heat
AOD64_RS06100	COG2267	carboxylic ester hydrolase activity
AOD64_RS06115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD64_RS06120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOD64_RS06125	COG5504	Zn-dependent protease
AOD64_RS06135	COG0180	Tryptophanyl-tRNA synthetase
AOD64_RS06145	COG4166	transmembrane transport
AOD64_RS06150	COG0601	transmembrane transport
AOD64_RS06155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD64_RS06160	COG0444	Belongs to the ABC transporter superfamily
AOD64_RS06165	COG4608	Belongs to the ABC transporter superfamily
AOD64_RS06170	COG0534	Mate efflux family protein
AOD64_RS06175	COG4166	transmembrane transport
AOD64_RS06195	COG0861	Integral membrane protein TerC family
AOD64_RS06200	COG4862	establishment of competence for transformation
AOD64_RS06205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD64_RS06215	COG1164	Oligoendopeptidase f
AOD64_RS06225	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOD64_RS06230	COG2346	COG2346, Truncated hemoglobins
AOD64_RS06235	COG4116	CYTH
AOD64_RS06245	COG2357	RelA SpoT domain protein
AOD64_RS06255	COG0564	pseudouridine synthase activity
AOD64_RS06270	COG0772	Belongs to the SEDS family
AOD64_RS06275	COG1216	Glycosyl transferase, family 2
AOD64_RS06275	COG0463	Glycosyl transferase, family 2
AOD64_RS06295	COG0463	Glycosyl transferase, family 2
AOD64_RS06295	COG0457	Tetratricopeptide repeat
AOD64_RS06315	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AOD64_RS06330	COG1091	dTDP-4-dehydrorhamnose reductase activity
AOD64_RS06375	COG2153	protein acetylation
AOD64_RS06385	COG2382	esterase
AOD64_RS06400	COG5492	domain, Protein
AOD64_RS06405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD64_RS06420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOD64_RS06420	COG0512	Glutamine amidotransferase of anthranilate synthase
AOD64_RS06455	COG1620	l-lactate permease
AOD64_RS06460	COG5634	Uncharacterized conserved protein (DUF2278)
AOD64_RS06510	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD64_RS06520	COG1476	TRANSCRIPTIONal
AOD64_RS06580	COG2226	methyltransferase
AOD64_RS06590	COG1686	Belongs to the peptidase S11 family
AOD64_RS06595	COG0681	Belongs to the peptidase S26 family
AOD64_RS06630	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS06635	COG3842	ATPase activity
AOD64_RS06640	COG1176	ABC-type spermidine putrescine transport system, permease component I
AOD64_RS06645	COG1177	transmembrane transport
AOD64_RS06650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AOD64_RS06660	COG2409	Drug exporters of the RND superfamily
AOD64_RS06670	COG0564	pseudouridine synthase activity
AOD64_RS06680	COG2340	Cysteine-rich secretory protein family
AOD64_RS06685	COG0247	lactate metabolic process
AOD64_RS06690	COG0277	FAD linked oxidase domain protein
AOD64_RS06695	COG3835	regulator
AOD64_RS06705	COG0745	RESPONSE REGULATOR receiver
AOD64_RS06710	COG5002	protein histidine kinase activity
AOD64_RS06715	COG2186	Transcriptional regulator
AOD64_RS06735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AOD64_RS06745	COG2116	formate transmembrane transporter activity
AOD64_RS06750	COG0861	Integral membrane protein TerC family
AOD64_RS06755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOD64_RS06765	COG2030	dehydratase
AOD64_RS06785	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS06790	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOD64_RS06795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD64_RS06800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOD64_RS06815	COG1840	ABC-type Fe3 transport system, periplasmic component
AOD64_RS06845	COG1349	DNA-binding transcription factor activity
AOD64_RS06870	COG2861	carbohydrate metabolic process
AOD64_RS06880	COG3852	Histidine kinase
AOD64_RS06885	COG1846	Transcriptional regulator
AOD64_RS06895	COG2318	DinB family
AOD64_RS06905	COG5002	protein histidine kinase activity
AOD64_RS06915	COG0720	synthase
AOD64_RS06930	COG4873	Protein conserved in bacteria
AOD64_RS06965	COG1780	Probably involved in ribonucleotide reductase function
AOD64_RS06980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOD64_RS06985	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOD64_RS06990	COG1725	Transcriptional regulator
AOD64_RS06995	COG1131	(ABC) transporter
AOD64_RS07005	COG1131	(ABC) transporter
AOD64_RS07010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AOD64_RS07025	COG1522	sequence-specific DNA binding
AOD64_RS07035	COG1335	isochorismatase
AOD64_RS07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOD64_RS07050	COG2070	2-Nitropropane dioxygenase
AOD64_RS07055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AOD64_RS07065	COG1696	Membrane protein involved in D-alanine export
AOD64_RS07090	COG0716	FMN binding
AOD64_RS07105	COG3173	Aminoglycoside phosphotransferase
AOD64_RS07125	COG0534	Mate efflux family protein
AOD64_RS07130	COG1968	undecaprenyl-diphosphatase activity
AOD64_RS07145	COG1846	Transcriptional regulator
AOD64_RS07155	COG1301	dicarboxylic acid transport
AOD64_RS07160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOD64_RS07165	COG4709	membrane
AOD64_RS07170	COG3874	Sporulation protein YtfJ
AOD64_RS07200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD64_RS07205	COG0028	Belongs to the TPP enzyme family
AOD64_RS07210	COG0440	acetolactate synthase activity
AOD64_RS07215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOD64_RS07225	COG0473	3-isopropylmalate dehydrogenase activity
AOD64_RS07250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOD64_RS07285	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOD64_RS07300	COG1183	phosphatidylcholine synthase activity
AOD64_RS07305	COG1368	sulfuric ester hydrolase activity
AOD64_RS07315	COG0019	diaminopimelate decarboxylase activity
AOD64_RS07335	COG0529	Catalyzes the synthesis of activated sulfate
AOD64_RS07340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOD64_RS07360	COG1648	precorrin-2 dehydrogenase activity
AOD64_RS07370	COG0733	neurotransmitter:sodium symporter activity
AOD64_RS07390	COG1757	Na H antiporter
AOD64_RS07405	COG4758	membrane
AOD64_RS07410	COG4585	Histidine kinase
AOD64_RS07415	COG2197	response regulator
AOD64_RS07425	COG1114	Component of the transport system for branched-chain amino acids
AOD64_RS07435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOD64_RS07460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOD64_RS07460	COG1017	nitric oxide dioxygenase activity
AOD64_RS07480	COG0730	response to heat
AOD64_RS07485	COG0306	phosphate transporter
AOD64_RS07490	COG1392	Phosphate transport regulator
AOD64_RS07495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD64_RS07510	COG3852	Histidine kinase
AOD64_RS07515	COG1801	Protein of unknown function DUF72
AOD64_RS07525	COG0582	viral genome integration into host DNA
AOD64_RS07530	COG5002	protein histidine kinase activity
AOD64_RS07550	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AOD64_RS07550	COG0392	lysyltransferase activity
AOD64_RS07565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOD64_RS07570	COG1686	Belongs to the peptidase S11 family
AOD64_RS07575	COG2715	membrane protein required for spore maturation
AOD64_RS07580	COG0700	Nucleoside recognition
AOD64_RS07585	COG1187	pseudouridine synthase activity
AOD64_RS07595	COG1333	cytochrome c biogenesis protein
AOD64_RS07600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOD64_RS07605	COG0745	RESPONSE REGULATOR receiver
AOD64_RS07610	COG5002	protein histidine kinase activity
AOD64_RS07615	COG2096	Adenosyltransferase
AOD64_RS07630	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AOD64_RS07635	COG1141	Ferredoxin
AOD64_RS07640	COG4955	Helix-turn-helix domain
AOD64_RS07645	COG0514	ATP-dependent DNA helicase (RecQ)
AOD64_RS07650	COG1266	CAAX protease self-immunity
AOD64_RS07670	COG4862	establishment of competence for transformation
AOD64_RS07675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOD64_RS07695	COG0492	ferredoxin-NADP+ reductase activity
AOD64_RS07700	COG0252	asparaginase activity
AOD64_RS07770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOD64_RS07785	COG0142	geranyltranstransferase activity
AOD64_RS07795	COG0142	geranyltranstransferase activity
AOD64_RS07815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOD64_RS07820	COG0457	Tetratricopeptide repeat
AOD64_RS07840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AOD64_RS07850	COG4347	Protein of unknown function (DUF1405)
AOD64_RS07865	COG2738	Putative neutral zinc metallopeptidase
AOD64_RS07875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS07885	COG1694	Mazg nucleotide pyrophosphohydrolase
AOD64_RS07900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOD64_RS07905	COG0438	transferase activity, transferring glycosyl groups
AOD64_RS07945	COG1199	ATP-dependent helicase activity
AOD64_RS07945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOD64_RS07965	COG3935	DnaD domain protein
AOD64_RS07970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOD64_RS07980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD64_RS07980	COG4499	WXG100 protein secretion system (Wss), protein YukC
AOD64_RS08035	COG0116	Belongs to the methyltransferase superfamily
AOD64_RS08045	COG1199	ATP-dependent helicase activity
AOD64_RS08050	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AOD64_RS08060	COG3173	Aminoglycoside phosphotransferase
AOD64_RS08065	COG0024	Methionine aminopeptidase
AOD64_RS08075	COG2233	PERMEase
AOD64_RS08080	COG2311	Membrane
AOD64_RS08085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOD64_RS08095	COG0456	acetyltransferase
AOD64_RS08130	COG0754	glutathionylspermidine amidase activity
AOD64_RS08145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOD64_RS08170	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOD64_RS08185	COG1215	transferase activity, transferring glycosyl groups
AOD64_RS08190	COG0438	transferase activity, transferring glycosyl groups
AOD64_RS08205	COG0454	-acetyltransferase
AOD64_RS08225	COG0328	RNA-DNA hybrid ribonuclease activity
AOD64_RS08265	COG1280	lysine exporter protein (LysE YggA)
AOD64_RS08280	COG3162	membrane
AOD64_RS08285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD64_RS08290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOD64_RS08300	COG0475	glutathione-regulated potassium exporter activity
AOD64_RS08305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOD64_RS08310	COG4978	Transcriptional regulator
AOD64_RS08310	COG0789	Transcriptional regulator
AOD64_RS08320	COG2323	membrane
AOD64_RS08325	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AOD64_RS08380	COG1923	regulation of RNA biosynthetic process
AOD64_RS08390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOD64_RS08395	COG1360	Flagellar Motor Protein
AOD64_RS08400	COG2201	protein-glutamate methylesterase activity
AOD64_RS08410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOD64_RS08410	COG1776	CheC inhibitor of MCP methylation
AOD64_RS08425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AOD64_RS08445	COG1256	bacterial-type flagellum assembly
AOD64_RS08450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOD64_RS08475	COG1815	bacterial-type flagellum-dependent cell motility
AOD64_RS08480	COG1558	bacterial-type flagellum-dependent cell motility
AOD64_RS08490	COG1766	The M ring may be actively involved in energy transduction
AOD64_RS08500	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOD64_RS08510	COG1157	protein secretion by the type III secretion system
AOD64_RS08560	COG0463	Glycosyl transferase, family 2
AOD64_RS08590	COG0463	Glycosyl transferase, family 2
AOD64_RS08590	COG0457	Tetratricopeptide repeat
AOD64_RS08615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AOD64_RS08620	COG0741	lytic transglycosylase activity
AOD64_RS08635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AOD64_RS08635	COG1776	CheC inhibitor of MCP methylation
AOD64_RS08645	COG1338	Plays a role in the flagellum-specific transport system
AOD64_RS08650	COG1987	bacterial-type flagellum assembly
AOD64_RS08660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOD64_RS08665	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AOD64_RS08675	COG4786	Flagellar basal body rod
AOD64_RS08680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOD64_RS08705	COG1309	transcriptional regulator
AOD64_RS08725	COG2329	Antibiotic biosynthesis monooxygenase
AOD64_RS08750	COG0583	DNA-binding transcription factor activity
AOD64_RS08755	COG3842	ATPase activity
AOD64_RS08760	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOD64_RS08770	COG1234	tRNA 3'-trailer cleavage
AOD64_RS08795	COG1686	Belongs to the peptidase S11 family
AOD64_RS08805	COG0406	alpha-ribazole phosphatase activity
AOD64_RS08835	COG0367	asparagine synthase
AOD64_RS08865	COG1802	Transcriptional regulator
AOD64_RS08870	COG0697	spore germination
AOD64_RS08875	COG0523	cobalamin synthesis protein
AOD64_RS08880	COG0701	Predicted permease
AOD64_RS08890	COG0438	transferase activity, transferring glycosyl groups
AOD64_RS08890	COG1216	Glycosyl transferase, family 2
AOD64_RS08895	COG1757	Na H antiporter
AOD64_RS08900	COG0114	fumarate hydratase activity
AOD64_RS08930	COG3340	Belongs to the peptidase S51 family
AOD64_RS08950	COG0785	Cytochrome C biogenesis protein
AOD64_RS08985	COG2733	membrane
AOD64_RS09020	COG1131	(ABC) transporter
AOD64_RS09035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD64_RS09040	COG0528	UMP kinase activity
AOD64_RS09050	COG1027	Aspartate ammonia-lyase
AOD64_RS09055	COG0281	malic enzyme
AOD64_RS09060	COG4191	Histidine kinase
AOD64_RS09065	COG0784	Response regulator, receiver
AOD64_RS09070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOD64_RS09130	COG1051	belongs to the nudix hydrolase family
AOD64_RS09135	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS09145	COG2814	Major facilitator Superfamily
AOD64_RS09160	COG1966	Carbon starvation protein
AOD64_RS09175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD64_RS09185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOD64_RS09195	COG2223	nitrite transmembrane transporter activity
AOD64_RS09200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOD64_RS09215	COG2244	polysaccharide biosynthetic process
AOD64_RS09220	COG0733	neurotransmitter:sodium symporter activity
AOD64_RS09230	COG5566	PFAM Mor transcription activator
AOD64_RS09235	COG2323	membrane
AOD64_RS09250	COG2084	Dehydrogenase
AOD64_RS09265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOD64_RS09275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD64_RS09280	COG0028	Belongs to the TPP enzyme family
AOD64_RS09285	COG0440	acetolactate synthase activity
AOD64_RS09290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AOD64_RS09300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOD64_RS09325	COG2814	Major facilitator Superfamily
AOD64_RS09330	COG3384	dioxygenase
AOD64_RS09340	COG3279	Response regulator of the LytR AlgR family
AOD64_RS09345	COG0427	acetyl-CoA hydrolase
AOD64_RS09365	COG1073	alpha beta
AOD64_RS09370	COG4166	transmembrane transport
AOD64_RS09395	COG0535	radical SAM domain protein
AOD64_RS09400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS09420	COG1914	H( )-stimulated, divalent metal cation uptake system
AOD64_RS09435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOD64_RS09470	COG2390	Transcriptional regulator
AOD64_RS09480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS09485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AOD64_RS09500	COG4224	UPF0291 protein
AOD64_RS09520	COG0006	proline dipeptidase activity
AOD64_RS09525	COG2132	Multicopper oxidase
AOD64_RS09540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOD64_RS09555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOD64_RS09570	COG2372	response to copper ion
AOD64_RS09570	COG1276	copper resistance
AOD64_RS09575	COG4549	nuclear export factor GLE1
AOD64_RS09585	COG0697	spore germination
AOD64_RS09590	COG0583	DNA-binding transcription factor activity
AOD64_RS09595	COG1959	2 iron, 2 sulfur cluster binding
AOD64_RS09600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOD64_RS09605	COG0778	Nitroreductase
AOD64_RS09620	COG0628	permease
AOD64_RS09630	COG1231	oxidoreductase activity
AOD64_RS09635	COG0523	cobalamin synthesis protein
AOD64_RS09650	COG0318	PFAM AMP-dependent synthetase and ligase
AOD64_RS09655	COG2030	dehydratase
AOD64_RS09660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD64_RS09670	COG0411	ABC transporter
AOD64_RS09690	COG0583	DNA-binding transcription factor activity
AOD64_RS09710	COG1846	Transcriptional regulator
AOD64_RS09720	COG1271	oxidase subunit
AOD64_RS09725	COG1294	oxidase, subunit
AOD64_RS09730	COG4988	ABC transporter
AOD64_RS09735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AOD64_RS09755	COG1686	Belongs to the peptidase S11 family
AOD64_RS09770	COG1388	LysM domain
AOD64_RS09770	COG0791	NLP P60 protein
AOD64_RS09780	COG1132	(ABC) transporter
AOD64_RS09785	COG1132	(ABC) transporter
AOD64_RS09790	COG0745	RESPONSE REGULATOR receiver
AOD64_RS09795	COG5002	protein histidine kinase activity
AOD64_RS09805	COG0300	oxidoreductase activity
AOD64_RS09840	COG0460	homoserine dehydrogenase
AOD64_RS09865	COG1316	TRANSCRIPTIONal
AOD64_RS09875	COG0745	RESPONSE REGULATOR receiver
AOD64_RS09880	COG5002	protein histidine kinase activity
AOD64_RS09895	COG1285	pathogenesis
AOD64_RS09900	COG1247	-acetyltransferase
AOD64_RS09920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOD64_RS09930	COG1082	Xylose isomerase domain protein TIM barrel
AOD64_RS09945	COG1279	arginine transmembrane transporter activity
AOD64_RS09955	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOD64_RS09995	COG2002	toxin-antitoxin pair type II binding
AOD64_RS10000	COG1404	Belongs to the peptidase S8 family
AOD64_RS10005	COG0640	Transcriptional regulator
AOD64_RS10010	COG0667	Aldo Keto reductase
AOD64_RS10015	COG2814	Major facilitator Superfamily
AOD64_RS10040	COG0840	transmembrane signaling receptor activity
AOD64_RS10060	COG3949	Membrane
AOD64_RS10065	COG0783	Belongs to the Dps family
AOD64_RS10080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOD64_RS10090	COG1231	oxidoreductase activity
AOD64_RS10100	COG4989	oxidoreductase activity
AOD64_RS10105	COG0523	cobalamin synthesis protein
AOD64_RS10110	COG0456	acetyltransferase
AOD64_RS10170	COG0803	Belongs to the bacterial solute-binding protein 9 family
AOD64_RS10170	COG3443	Belongs to the bacterial solute-binding protein 9 family
AOD64_RS10180	COG0702	epimerase
AOD64_RS10190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOD64_RS10200	COG4166	transmembrane transport
AOD64_RS10215	COG0406	alpha-ribazole phosphatase activity
AOD64_RS10225	COG5337	Spore coat protein CotH
AOD64_RS10230	COG1051	belongs to the nudix hydrolase family
AOD64_RS10235	COG0586	Pfam SNARE associated Golgi protein
AOD64_RS10240	COG2244	polysaccharide biosynthetic process
AOD64_RS10250	COG0701	Predicted permease
AOD64_RS10255	COG3689	TIGRFAM TIGR03943 family protein
AOD64_RS10260	COG1607	acyl-coa hydrolase
AOD64_RS10265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD64_RS10280	COG0702	epimerase
AOD64_RS10285	COG2839	Protein conserved in bacteria
AOD64_RS10290	COG1253	flavin adenine dinucleotide binding
AOD64_RS10305	COG1114	Component of the transport system for branched-chain amino acids
AOD64_RS10310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD64_RS10330	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS10340	COG1876	peptidase activity
AOD64_RS10350	COG0154	amidase activity
AOD64_RS10355	COG2211	Major facilitator Superfamily
AOD64_RS10375	COG0561	phosphatase activity
AOD64_RS10385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOD64_RS10390	COG4106	trans-aconitate 2-methyltransferase activity
AOD64_RS10405	COG1819	glycosyl
AOD64_RS10410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS10415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS10440	COG0456	acetyltransferase
AOD64_RS10490	COG3874	Sporulation protein YtfJ
AOD64_RS10515	COG2226	methyltransferase
AOD64_RS10535	COG1082	Xylose isomerase domain protein TIM barrel
AOD64_RS10540	COG0346	lactoylglutathione lyase activity
AOD64_RS10550	COG0604	alcohol dehydrogenase
AOD64_RS10555	COG1595	DNA-templated transcription, initiation
AOD64_RS10580	COG0386	Belongs to the glutathione peroxidase family
AOD64_RS10585	COG1305	Transglutaminase-like
AOD64_RS10590	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AOD64_RS10595	COG0714	Associated with various cellular activities
AOD64_RS10610	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AOD64_RS10615	COG1140	nitrate reductase beta subunit
AOD64_RS10620	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AOD64_RS10625	COG2181	nitrate reductase activity
AOD64_RS10645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOD64_RS10650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOD64_RS10655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD64_RS10660	COG0303	'Molybdopterin
AOD64_RS10665	COG0314	molybdopterin synthase activity
AOD64_RS10675	COG2223	nitrite transmembrane transporter activity
AOD64_RS10690	COG1648	precorrin-2 dehydrogenase activity
AOD64_RS10700	COG1587	Uroporphyrinogen-III synthase
AOD64_RS10700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOD64_RS10705	COG2146	nitrite reductase [NAD(P)H] activity
AOD64_RS10710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOD64_RS10715	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AOD64_RS10750	COG2359	stage V sporulation protein S
AOD64_RS10765	COG5632	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS10780	COG1418	mRNA catabolic process
AOD64_RS10785	COG0488	(ABC) transporter
AOD64_RS10800	COG0629	single-stranded DNA binding
AOD64_RS10815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOD64_RS10820	COG1413	lyase activity
AOD64_RS10835	COG2521	methyltransferase
AOD64_RS10835	COG2136	Putative SAM-dependent methyltransferase
AOD64_RS10840	COG0018	arginyl-trna synthetase
AOD64_RS10865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOD64_RS10880	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOD64_RS10885	COG0017	Asparaginyl-tRNA synthetase
AOD64_RS10905	COG1674	ftsk spoiiie
AOD64_RS11005	COG1929	Belongs to the glycerate kinase type-1 family
AOD64_RS11010	COG0471	metal ion transport
AOD64_RS11015	COG0745	RESPONSE REGULATOR receiver
AOD64_RS11020	COG3850	Histidine kinase
AOD64_RS11020	COG5002	protein histidine kinase activity
AOD64_RS11035	COG0733	neurotransmitter:sodium symporter activity
AOD64_RS11060	COG2610	gluconate transmembrane transporter activity
AOD64_RS11065	COG1454	alcohol dehydrogenase
AOD64_RS11070	COG1794	racemase activity, acting on amino acids and derivatives
AOD64_RS11080	COG0456	acetyltransferase
AOD64_RS11095	COG1131	(ABC) transporter
AOD64_RS11100	COG4473	ABC transporter
AOD64_RS11110	COG0546	phosphoglycolate phosphatase activity
AOD64_RS11130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD64_RS11145	COG0768	penicillin binding
AOD64_RS11150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOD64_RS11155	COG0204	Acyl-transferase
AOD64_RS11160	COG1272	protein, Hemolysin III
AOD64_RS11170	COG0805	protein transport
AOD64_RS11180	COG1307	EDD domain protein, DegV family
AOD64_RS11185	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AOD64_RS11190	COG1999	signal sequence binding
AOD64_RS11195	COG0071	Belongs to the small heat shock protein (HSP20) family
AOD64_RS11200	COG0367	asparagine synthase
AOD64_RS11220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS11225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOD64_RS11260	COG0668	transmembrane transport
AOD64_RS11265	COG4585	Histidine kinase
AOD64_RS11265	COG2203	Gaf domain
AOD64_RS11270	COG2197	response regulator
AOD64_RS11280	COG1737	Transcriptional regulator
AOD64_RS11285	COG1064	alcohol dehydrogenase
AOD64_RS11315	COG1070	Carbohydrate kinase
AOD64_RS11320	COG1070	Carbohydrate kinase
AOD64_RS11350	COG0517	IMP dehydrogenase activity
AOD64_RS11350	COG1125	glycine betaine transport
AOD64_RS11355	COG1174	glycine betaine transport
AOD64_RS11390	COG1253	flavin adenine dinucleotide binding
AOD64_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS11400	COG5506	Protein of unknown function (DUF1694)
AOD64_RS11415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOD64_RS11420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOD64_RS11425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOD64_RS11430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD64_RS11435	COG0456	acetyltransferase
AOD64_RS11440	COG3829	transcription factor binding
AOD64_RS11445	COG1509	lysine 2,3-aminomutase activity
AOD64_RS11485	COG4326	sporulation control protein
AOD64_RS11490	COG0671	phosphoesterase, PA-phosphatase related
AOD64_RS11495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AOD64_RS11500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD64_RS11530	COG1787	Restriction endonuclease
AOD64_RS11530	COG1715	Restriction endonuclease
AOD64_RS11615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOD64_RS11655	COG4499	WXG100 protein secretion system (Wss), protein YukC
AOD64_RS11655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD64_RS11665	COG2814	Major facilitator Superfamily
AOD64_RS11670	COG4841	protein insertion into membrane
AOD64_RS11675	COG0372	Belongs to the citrate synthase family
AOD64_RS11680	COG2079	MmgE PrpD family protein
AOD64_RS11685	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AOD64_RS11690	COG1960	acyl-CoA dehydrogenase activity
AOD64_RS11695	COG2084	Dehydrogenase
AOD64_RS11705	COG1280	lysine exporter protein (LysE YggA)
AOD64_RS11710	COG1024	Enoyl-CoA hydratase
AOD64_RS11725	COG0420	3'-5' exonuclease activity
AOD64_RS11730	COG0419	ATPase involved in DNA repair
AOD64_RS11760	COG2223	nitrite transmembrane transporter activity
AOD64_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS11770	COG1169	isochorismate synthase
AOD64_RS11775	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOD64_RS11780	COG1535	isochorismatase
AOD64_RS11780	COG3433	isochorismatase activity
AOD64_RS11785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOD64_RS11790	COG3251	PFAM MbtH domain protein
AOD64_RS11795	COG2814	Major facilitator Superfamily
AOD64_RS11810	COG0776	regulation of translation
AOD64_RS11820	COG2318	DinB family
AOD64_RS11830	COG1115	amino acid carrier protein
AOD64_RS11845	COG2329	Antibiotic biosynthesis monooxygenase
AOD64_RS11850	COG1187	pseudouridine synthase activity
AOD64_RS11855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOD64_RS11870	COG0596	Alpha beta hydrolase
AOD64_RS11875	COG2814	Major facilitator Superfamily
AOD64_RS11895	COG2226	methyltransferase
AOD64_RS11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS11975	COG1247	-acetyltransferase
AOD64_RS12005	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AOD64_RS12015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS12025	COG1278	Cold shock
AOD64_RS12040	COG0010	Belongs to the arginase family
AOD64_RS12045	COG0561	phosphatase activity
AOD64_RS12090	COG0583	DNA-binding transcription factor activity
AOD64_RS12095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOD64_RS12110	COG0583	DNA-binding transcription factor activity
AOD64_RS12115	COG2258	MOSC domain
AOD64_RS12130	COG1132	(ABC) transporter
AOD64_RS12135	COG1132	(ABC) transporter
AOD64_RS12155	COG1396	sequence-specific DNA binding
AOD64_RS12180	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AOD64_RS12185	COG1595	DNA-templated transcription, initiation
AOD64_RS12210	COG1649	PFAM Uncharacterised BCR, COG1649
AOD64_RS12235	COG2971	BadF BadG BcrA BcrD
AOD64_RS12240	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOD64_RS12245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOD64_RS12265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS12295	COG1309	transcriptional regulator
AOD64_RS12310	COG1136	(ABC) transporter
AOD64_RS12310	COG0577	efflux transmembrane transporter activity
AOD64_RS12315	COG3615	Tellurite resistance protein tehB
AOD64_RS12315	COG0500	methyltransferase
AOD64_RS12325	COG2226	methyltransferase
AOD64_RS12330	COG3961	Belongs to the TPP enzyme family
AOD64_RS12335	COG1846	Transcriptional regulator
AOD64_RS12375	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOD64_RS12390	COG1595	DNA-templated transcription, initiation
AOD64_RS12400	COG0768	penicillin binding
AOD64_RS12410	COG2367	Beta-lactamase
AOD64_RS12415	COG0671	phosphoesterase, PA-phosphatase related
AOD64_RS12420	COG1609	Transcriptional regulator
AOD64_RS12425	COG2814	Major facilitator Superfamily
AOD64_RS12430	COG0673	inositol 2-dehydrogenase activity
AOD64_RS12440	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS12455	COG0191	fructose-bisphosphate aldolase activity
AOD64_RS12460	COG3718	enzyme involved in inositol metabolism
AOD64_RS12475	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS12485	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS12495	COG0457	Tetratricopeptide repeat
AOD64_RS12500	COG1476	TRANSCRIPTIONal
AOD64_RS12515	COG1876	peptidase activity
AOD64_RS12535	COG1309	transcriptional regulator
AOD64_RS12540	COG0488	(ABC) transporter
AOD64_RS12555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS12565	COG1252	NADH dehydrogenase
AOD64_RS12570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD64_RS12585	COG1131	(ABC) transporter
AOD64_RS12595	COG1309	transcriptional regulator
AOD64_RS12610	COG1960	acyl-CoA dehydrogenase activity
AOD64_RS12615	COG0439	Biotin carboxylase
AOD64_RS12620	COG0511	ligase activity, forming carbon-carbon bonds
AOD64_RS12625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOD64_RS12630	COG1024	Enoyl-CoA hydratase
AOD64_RS12635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOD64_RS12640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOD64_RS12650	COG1247	-acetyltransferase
AOD64_RS12655	COG0572	uridine kinase
AOD64_RS12665	COG2318	DinB family
AOD64_RS12700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOD64_RS12740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOD64_RS12740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOD64_RS12765	COG2814	Major facilitator Superfamily
AOD64_RS12785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOD64_RS12805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS12820	COG1063	alcohol dehydrogenase
AOD64_RS12835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOD64_RS12840	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOD64_RS12855	COG3773	Cell wall hydrolase
AOD64_RS12865	COG0745	RESPONSE REGULATOR receiver
AOD64_RS12895	COG1136	(ABC) transporter
AOD64_RS12920	COG0460	homoserine dehydrogenase
AOD64_RS12925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS12935	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOD64_RS13010	COG2124	cytochrome p450
AOD64_RS13045	COG0561	phosphatase activity
AOD64_RS13055	COG5002	protein histidine kinase activity
AOD64_RS13060	COG0768	penicillin binding
AOD64_RS13065	COG1819	glycosyl
AOD64_RS13070	COG1794	racemase activity, acting on amino acids and derivatives
AOD64_RS13080	COG1122	ATPase activity
AOD64_RS13090	COG2205	protein histidine kinase activity
AOD64_RS13100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD64_RS13105	COG0604	alcohol dehydrogenase
AOD64_RS13110	COG0768	penicillin binding
AOD64_RS13120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD64_RS13155	COG0693	protein deglycase activity
AOD64_RS13185	COG2814	Major facilitator Superfamily
AOD64_RS13200	COG0584	glycerophosphoryl diester phosphodiesterase
AOD64_RS13220	COG0697	spore germination
AOD64_RS13245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD64_RS13255	COG2223	nitrite transmembrane transporter activity
AOD64_RS13270	COG2816	NAD+ diphosphatase activity
AOD64_RS13275	COG0592	DNA-directed DNA polymerase activity
AOD64_RS13280	COG1051	belongs to the nudix hydrolase family
AOD64_RS13315	COG3878	Protein conserved in bacteria
AOD64_RS13345	COG4667	esterase of the alpha-beta hydrolase superfamily
AOD64_RS13370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOD64_RS13385	COG0322	excinuclease ABC activity
AOD64_RS13425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD64_RS13450	COG1011	Hydrolase
AOD64_RS13470	COG0076	glutamate decarboxylase activity
AOD64_RS13485	COG1523	belongs to the glycosyl hydrolase 13 family
AOD64_RS13490	COG3227	Zinc metalloprotease (Elastase)
AOD64_RS13510	COG0201	protein transport
AOD64_RS13520	COG0697	spore germination
AOD64_RS13525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS13555	COG4129	membrane
AOD64_RS13560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS13575	COG2959	enzyme of heme biosynthesis
AOD64_RS13595	COG3483	tryptophan 2,3-dioxygenase activity
AOD64_RS13600	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AOD64_RS13605	COG3844	kynureninase activity
AOD64_RS13610	COG1309	transcriptional regulator
AOD64_RS13640	COG3284	Transcriptional regulator
AOD64_RS13660	COG1349	DNA-binding transcription factor activity
AOD64_RS13680	COG1959	2 iron, 2 sulfur cluster binding
AOD64_RS13695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOD64_RS13700	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD64_RS13705	COG0022	dehydrogenase e1 component
AOD64_RS13710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOD64_RS13720	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS13725	COG0456	acetyltransferase
AOD64_RS13725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD64_RS13760	COG4176	ABC-type proline glycine betaine transport system permease component
AOD64_RS13765	COG0517	IMP dehydrogenase activity
AOD64_RS13765	COG4175	Glycine betaine
AOD64_RS13790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AOD64_RS13795	COG2153	protein acetylation
AOD64_RS13800	COG3397	chitin binding
AOD64_RS13815	COG2205	protein histidine kinase activity
AOD64_RS13845	COG2333	competence protein COMEC
AOD64_RS13845	COG0658	competence protein
AOD64_RS13895	COG3973	AAA domain
AOD64_RS13910	COG2105	PFAM AIG2 family protein
AOD64_RS13915	COG0514	ATP-dependent DNA helicase (RecQ)
AOD64_RS13945	COG4637	Psort location Cytoplasmic, score
AOD64_RS13970	COG3397	chitin binding
AOD64_RS13980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOD64_RS13985	COG1115	amino acid carrier protein
AOD64_RS13990	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS13995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOD64_RS14005	COG3938	Belongs to the proline racemase family
AOD64_RS14010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOD64_RS14050	COG0586	Pfam SNARE associated Golgi protein
AOD64_RS14065	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AOD64_RS14070	COG0519	Catalyzes the synthesis of GMP from XMP
AOD64_RS14075	COG4166	transmembrane transport
AOD64_RS14085	COG4948	Mandelate Racemase Muconate Lactonizing
AOD64_RS14125	COG2936	dipeptidyl-peptidase activity
AOD64_RS14130	COG5002	protein histidine kinase activity
AOD64_RS14135	COG0745	RESPONSE REGULATOR receiver
AOD64_RS14175	COG1307	EDD domain protein, DegV family
AOD64_RS14195	COG2814	Major facilitator Superfamily
AOD64_RS14205	COG1664	Polymer-forming cytoskeletal
AOD64_RS14210	COG0789	Transcriptional regulator
AOD64_RS14215	COG4533	DNA binding
AOD64_RS14220	COG0477	Major facilitator Superfamily
AOD64_RS14220	COG2814	Major facilitator Superfamily
AOD64_RS14240	COG2261	transglycosylase associated protein
AOD64_RS14255	COG2226	methyltransferase
AOD64_RS14290	COG0436	Aminotransferase
AOD64_RS14295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AOD64_RS14300	COG5146	pantothenate kinase activity
AOD64_RS14325	COG1131	(ABC) transporter
AOD64_RS14375	COG0628	permease
AOD64_RS14390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOD64_RS14395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD64_RS14400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOD64_RS14405	COG1116	anion transmembrane transporter activity
AOD64_RS14425	COG2816	NAD+ diphosphatase activity
AOD64_RS14445	COG2746	aminoglycoside 3-N-acetyltransferase activity
AOD64_RS14470	COG0697	spore germination
AOD64_RS14475	COG2318	DinB family
AOD64_RS14495	COG4912	Dna alkylation repair
AOD64_RS14515	COG0861	Integral membrane protein TerC family
AOD64_RS14520	COG1368	sulfuric ester hydrolase activity
AOD64_RS14525	COG0488	(ABC) transporter
AOD64_RS14535	COG2409	Drug exporters of the RND superfamily
AOD64_RS14535	COG1033	growth of symbiont in host cell
AOD64_RS14540	COG1033	growth of symbiont in host cell
AOD64_RS14540	COG2409	Drug exporters of the RND superfamily
AOD64_RS14545	COG2409	Drug exporters of the RND superfamily
AOD64_RS14545	COG1033	growth of symbiont in host cell
AOD64_RS14550	COG1309	transcriptional regulator
AOD64_RS14565	COG0287	Prephenate dehydrogenase
AOD64_RS14570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AOD64_RS14575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AOD64_RS14580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AOD64_RS14580	COG1605	Chorismate mutase
AOD64_RS14615	COG1388	LysM domain
AOD64_RS14615	COG3584	3D domain protein
AOD64_RS14625	COG1595	DNA-templated transcription, initiation
AOD64_RS14650	COG1879	ABC-type sugar transport system periplasmic component
AOD64_RS14660	COG1172	Belongs to the binding-protein-dependent transport system permease family
AOD64_RS14670	COG2390	Transcriptional regulator
AOD64_RS14705	COG2329	Antibiotic biosynthesis monooxygenase
AOD64_RS14725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS14735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AOD64_RS14740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD64_RS14745	COG4187	Peptidase family M20/M25/M40
AOD64_RS14750	COG1414	Transcriptional regulator
AOD64_RS14755	COG0833	amino acid
AOD64_RS14760	COG1690	Belongs to the RtcB family
AOD64_RS14765	COG3239	Fatty acid desaturase
AOD64_RS14770	COG1785	Belongs to the alkaline phosphatase family
AOD64_RS14780	COG3655	Transcriptional regulator
AOD64_RS14795	COG4377	Putative membrane peptidase family (DUF2324)
AOD64_RS14805	COG3279	Response regulator of the LytR AlgR family
AOD64_RS14815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS14820	COG0346	lactoylglutathione lyase activity
AOD64_RS14840	COG0714	Associated with various cellular activities
AOD64_RS14865	COG0463	Glycosyl transferase, family 2
AOD64_RS14890	COG0463	Glycosyl transferase, family 2
AOD64_RS14900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOD64_RS14905	COG0753	catalase activity
AOD64_RS14915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOD64_RS14940	COG0714	Associated with various cellular activities
AOD64_RS14950	COG0778	Nitroreductase
AOD64_RS14955	COG1846	Transcriptional regulator
AOD64_RS14990	COG1725	Transcriptional regulator
AOD64_RS15000	COG1136	(ABC) transporter
AOD64_RS15000	COG0577	efflux transmembrane transporter activity
AOD64_RS15025	COG2207	Transcriptional regulator
AOD64_RS15030	COG0456	acetyltransferase
AOD64_RS15050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS15070	COG0642	Histidine kinase
AOD64_RS15075	COG0745	RESPONSE REGULATOR receiver
AOD64_RS15080	COG0596	Alpha beta hydrolase
AOD64_RS15110	COG0730	response to heat
AOD64_RS15120	COG0833	amino acid
AOD64_RS15130	COG4335	DNA alkylation repair
AOD64_RS15170	COG0768	penicillin binding
AOD64_RS15180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOD64_RS15220	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AOD64_RS15225	COG1414	Transcriptional regulator
AOD64_RS15240	COG0860	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS15245	COG0640	Transcriptional regulator
AOD64_RS15255	COG1960	acyl-CoA dehydrogenase activity
AOD64_RS15275	COG3314	Sporulation integral membrane protein YlbJ
AOD64_RS15290	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AOD64_RS15305	COG0574	Belongs to the PEP-utilizing enzyme family
AOD64_RS15305	COG3848	Pyruvate phosphate dikinase
AOD64_RS15310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS15325	COG5577	PFAM Coat F domain
AOD64_RS15330	COG3403	YqcI/YcgG family
AOD64_RS15335	COG1280	lysine exporter protein (LysE YggA)
AOD64_RS15370	COG1063	alcohol dehydrogenase
AOD64_RS15385	COG1027	Aspartate ammonia-lyase
AOD64_RS15390	COG0252	asparaginase activity
AOD64_RS15395	COG1396	sequence-specific DNA binding
AOD64_RS15405	COG0322	excinuclease ABC activity
AOD64_RS15410	COG0531	amino acid
AOD64_RS15415	COG1114	Component of the transport system for branched-chain amino acids
AOD64_RS15420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD64_RS15430	COG0281	malic enzyme
AOD64_RS15450	COG0531	amino acid
AOD64_RS15455	COG0697	spore germination
AOD64_RS15460	COG0784	Response regulator, receiver
AOD64_RS15470	COG2066	Belongs to the glutaminase family
AOD64_RS15500	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS15505	COG0753	catalase activity
AOD64_RS15510	COG2267	carboxylic ester hydrolase activity
AOD64_RS15515	COG1335	isochorismatase
AOD64_RS15535	COG0583	DNA-binding transcription factor activity
AOD64_RS15580	COG0415	Belongs to the DNA photolyase family
AOD64_RS15585	COG0288	reversible hydration of carbon dioxide
AOD64_RS15595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOD64_RS15600	COG5609	conserved protein (DUF2294)
AOD64_RS15610	COG1575	Belongs to the MenA family. Type 1 subfamily
AOD64_RS15615	COG2267	carboxylic ester hydrolase activity
AOD64_RS15620	COG0803	Belongs to the bacterial solute-binding protein 9 family
AOD64_RS15625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOD64_RS15630	COG1121	(ABC) transporter
AOD64_RS15660	COG0798	PFAM Bile acid sodium symporter
AOD64_RS15665	COG0346	lactoylglutathione lyase activity
AOD64_RS15670	COG0640	Transcriptional regulator
AOD64_RS15685	COG0443	Heat shock 70 kDa protein
AOD64_RS15700	COG1522	sequence-specific DNA binding
AOD64_RS15715	COG0346	lactoylglutathione lyase activity
AOD64_RS15740	COG2169	Transcriptional regulator
AOD64_RS15785	COG2814	Major facilitator Superfamily
AOD64_RS15810	COG0745	RESPONSE REGULATOR receiver
AOD64_RS15815	COG3850	Histidine kinase
AOD64_RS15815	COG5002	protein histidine kinase activity
AOD64_RS15845	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOD64_RS15870	COG1476	TRANSCRIPTIONal
AOD64_RS15885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS15890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOD64_RS15900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD64_RS15905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AOD64_RS15920	COG1136	(ABC) transporter
AOD64_RS15925	COG0577	efflux transmembrane transporter activity
AOD64_RS15945	COG3850	Histidine kinase
AOD64_RS15945	COG5002	protein histidine kinase activity
AOD64_RS15955	COG2364	Membrane
AOD64_RS15960	COG1846	Transcriptional regulator
AOD64_RS15970	COG2808	Putative FMN-binding domain
AOD64_RS15975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS15980	COG2271	Major facilitator Superfamily
AOD64_RS15985	COG1556	Lactate utilization protein
AOD64_RS15990	COG1139	Iron-sulfur cluster binding protein
AOD64_RS16000	COG0583	DNA-binding transcription factor activity
AOD64_RS16010	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOD64_RS16035	COG0738	Major facilitator superfamily
AOD64_RS16040	COG0673	inositol 2-dehydrogenase activity
AOD64_RS16045	COG0561	phosphatase activity
AOD64_RS16055	COG1609	Transcriptional regulator
AOD64_RS16060	COG0457	Tetratricopeptide repeat
AOD64_RS16080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOD64_RS16110	COG0534	Mate efflux family protein
AOD64_RS16125	COG2814	Major facilitator Superfamily
AOD64_RS16130	COG1309	transcriptional regulator
AOD64_RS16145	COG0814	amino acid
AOD64_RS16150	COG1760	l-serine dehydratase
AOD64_RS16155	COG1760	l-serine dehydratase
AOD64_RS16165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOD64_RS16170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AOD64_RS16180	COG1335	isochorismatase
AOD64_RS16185	COG1522	sequence-specific DNA binding
AOD64_RS16190	COG0531	amino acid
AOD64_RS16205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOD64_RS16225	COG1595	DNA-templated transcription, initiation
AOD64_RS16240	COG0662	Cupin 2, conserved barrel domain protein
AOD64_RS16250	COG2207	Transcriptional regulator
AOD64_RS16250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS16305	COG0477	Major facilitator Superfamily
AOD64_RS16315	COG1846	Transcriptional regulator
AOD64_RS16320	COG2814	Major facilitator Superfamily
AOD64_RS16330	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AOD64_RS16335	COG1131	(ABC) transporter
AOD64_RS16355	COG2076	Multidrug Resistance protein
AOD64_RS16360	COG1309	transcriptional regulator
AOD64_RS16375	COG2031	fatty acid transporter
AOD64_RS16385	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOD64_RS16415	COG1122	ATPase activity
AOD64_RS16420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AOD64_RS16435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOD64_RS16440	COG1288	antiporter activity
AOD64_RS16445	COG2356	endonuclease I
AOD64_RS16460	COG3620	sequence-specific DNA binding
AOD64_RS16465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOD64_RS16470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOD64_RS16475	COG0124	histidyl-tRNA synthetase
AOD64_RS16490	COG1733	regulation of RNA biosynthetic process
AOD64_RS16495	COG0778	Nitroreductase
AOD64_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS16525	COG1131	(ABC) transporter
AOD64_RS16550	COG1011	Hydrolase
AOD64_RS16560	COG2365	Tyrosine phosphatase family
AOD64_RS16585	COG0346	lactoylglutathione lyase activity
AOD64_RS16590	COG1940	carbohydrate kinase activity
AOD64_RS16595	COG0738	Major facilitator superfamily
AOD64_RS16600	COG0110	maltose O-acetyltransferase activity
AOD64_RS16615	COG0577	efflux transmembrane transporter activity
AOD64_RS16615	COG1136	(ABC) transporter
AOD64_RS16625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AOD64_RS16630	COG0628	permease
AOD64_RS16650	COG2226	methyltransferase
AOD64_RS16660	COG0477	Major facilitator Superfamily
AOD64_RS16690	COG1253	flavin adenine dinucleotide binding
AOD64_RS16695	COG0789	Transcriptional regulator
AOD64_RS16700	COG0697	spore germination
AOD64_RS16705	COG1357	PFAM Pentapeptide repeats (8 copies)
AOD64_RS16710	COG3813	Protein conserved in bacteria
AOD64_RS16715	COG2706	6-phosphogluconolactonase activity
AOD64_RS16720	COG1070	Carbohydrate kinase
AOD64_RS16730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOD64_RS16735	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AOD64_RS16745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOD64_RS16750	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AOD64_RS16755	COG0604	alcohol dehydrogenase
AOD64_RS16760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOD64_RS16770	COG3321	synthase
AOD64_RS16770	COG0604	alcohol dehydrogenase
AOD64_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS16805	COG0656	L-ascorbic acid biosynthetic process
AOD64_RS16810	COG2814	Major facilitator Superfamily
AOD64_RS16825	COG0346	lactoylglutathione lyase activity
AOD64_RS16830	COG0814	amino acid
AOD64_RS16855	COG1393	Belongs to the ArsC family
AOD64_RS16865	COG1733	regulation of RNA biosynthetic process
AOD64_RS16870	COG2188	Transcriptional regulator
AOD64_RS16880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AOD64_RS16885	COG1733	regulation of RNA biosynthetic process
AOD64_RS16890	COG1733	regulation of RNA biosynthetic process
AOD64_RS16905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS16925	COG0384	phenazine biosynthesis protein PhzF
AOD64_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS16945	COG0318	PFAM AMP-dependent synthetase and ligase
AOD64_RS16955	COG1733	regulation of RNA biosynthetic process
AOD64_RS16990	COG1191	sigma factor activity
AOD64_RS17005	COG1309	transcriptional regulator
AOD64_RS17025	COG3152	Membrane
AOD64_RS17050	COG1151	hydroxylamine reductase activity
AOD64_RS17060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS17065	COG3409	Peptidoglycan-binding domain 1 protein
AOD64_RS17065	COG3757	hydrolase, family 25
AOD64_RS17100	COG2072	flavoprotein involved in K transport
AOD64_RS17140	COG1113	amino acid transport
AOD64_RS17145	COG2814	Major facilitator Superfamily
AOD64_RS17180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOD64_RS17185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOD64_RS17205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS17215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS17220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS17225	COG3739	integral membrane protein
AOD64_RS17230	COG0384	phenazine biosynthesis protein PhzF
AOD64_RS17260	COG0583	DNA-binding transcription factor activity
AOD64_RS17280	COG1193	negative regulation of DNA recombination
AOD64_RS17295	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AOD64_RS17300	COG1164	Oligoendopeptidase f
AOD64_RS17305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOD64_RS17335	COG0584	glycerophosphoryl diester phosphodiesterase
AOD64_RS17360	COG0640	Transcriptional regulator
AOD64_RS17365	COG0604	alcohol dehydrogenase
AOD64_RS17385	COG2808	Putative FMN-binding domain
AOD64_RS17390	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD64_RS17400	COG0385	Bile acid
AOD64_RS17405	COG0277	FAD linked oxidase domain protein
AOD64_RS17440	COG1216	Glycosyl transferase, family 2
AOD64_RS17445	COG1024	Enoyl-CoA hydratase
AOD64_RS17455	COG1285	pathogenesis
AOD64_RS17465	COG2514	catechol 2,3-dioxygenase activity
AOD64_RS17470	COG2720	vancomycin resistance protein
AOD64_RS17510	COG0716	FMN binding
AOD64_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS17550	COG0165	Argininosuccinate lyase
AOD64_RS17565	COG4145	pantothenate transmembrane transporter activity
AOD64_RS17575	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS17590	COG1657	PFAM Prenyltransferase squalene oxidase
AOD64_RS17595	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AOD64_RS17600	COG2962	Rard protein
AOD64_RS17605	COG3326	Membrane
AOD64_RS17620	COG0489	protein tyrosine kinase activity
AOD64_RS17630	COG0314	molybdopterin synthase activity
AOD64_RS17635	COG0303	'Molybdopterin
AOD64_RS17640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD64_RS17645	COG2116	formate transmembrane transporter activity
AOD64_RS17655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOD64_RS17660	COG5609	conserved protein (DUF2294)
AOD64_RS17665	COG2427	Protein of unknown function (DUF1641)
AOD64_RS17670	COG3383	formate dehydrogenase (NAD+) activity
AOD64_RS17680	COG0697	spore germination
AOD64_RS17720	COG2226	methyltransferase
AOD64_RS17725	COG4166	transmembrane transport
AOD64_RS17730	COG4166	transmembrane transport
AOD64_RS17735	COG4166	transmembrane transport
AOD64_RS17740	COG1301	dicarboxylic acid transport
AOD64_RS17745	COG1316	TRANSCRIPTIONal
AOD64_RS17755	COG1595	DNA-templated transcription, initiation
AOD64_RS17780	COG1131	(ABC) transporter
AOD64_RS17790	COG0673	inositol 2-dehydrogenase activity
AOD64_RS17795	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AOD64_RS17800	COG0187	DNA topoisomerase II activity
AOD64_RS17810	COG1832	CoA-binding protein
AOD64_RS17815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOD64_RS17820	COG0745	RESPONSE REGULATOR receiver
AOD64_RS17835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AOD64_RS17840	COG4841	protein insertion into membrane
AOD64_RS17845	COG0824	Thioesterase
AOD64_RS17875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD64_RS17885	COG2274	protein secretion by the type I secretion system
AOD64_RS17890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOD64_RS17920	COG2211	Major facilitator Superfamily
AOD64_RS17930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOD64_RS17945	COG0183	Belongs to the thiolase family
AOD64_RS17950	COG0318	PFAM AMP-dependent synthetase and ligase
AOD64_RS17955	COG1268	BioY protein
AOD64_RS17960	COG0318	PFAM AMP-dependent synthetase and ligase
AOD64_RS18005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS18015	COG5002	protein histidine kinase activity
AOD64_RS18020	COG0400	carboxylic ester hydrolase activity
AOD64_RS18025	COG0346	lactoylglutathione lyase activity
AOD64_RS18030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOD64_RS18035	COG0069	glutamate synthase activity
AOD64_RS18040	COG1902	pentaerythritol trinitrate reductase activity
AOD64_RS18045	COG1329	Transcriptional regulator
AOD64_RS18050	COG0010	Belongs to the arginase family
AOD64_RS18075	COG2226	methyltransferase
AOD64_RS18130	COG4846	Membrane protein involved in cytochrome C biogenesis
AOD64_RS18135	COG0785	Cytochrome C biogenesis protein
AOD64_RS18145	COG0583	DNA-binding transcription factor activity
AOD64_RS18150	COG1380	Effector of murein hydrolase LrgA
AOD64_RS18155	COG1346	cytolysis
AOD64_RS18170	COG0730	response to heat
AOD64_RS18180	COG5632	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS18180	COG3409	Peptidoglycan-binding domain 1 protein
AOD64_RS18195	COG1132	(ABC) transporter
AOD64_RS18200	COG1132	(ABC) transporter
AOD64_RS18235	COG3639	organic phosphonate transmembrane transporter activity
AOD64_RS18240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AOD64_RS18255	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS18265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOD64_RS18285	COG1695	Transcriptional regulator
AOD64_RS18320	COG5632	N-Acetylmuramoyl-L-alanine amidase
AOD64_RS18320	COG1388	LysM domain
AOD64_RS18320	COG3409	Peptidoglycan-binding domain 1 protein
AOD64_RS18325	COG4824	toxin secretion phage lysis holin
AOD64_RS18490	COG1595	DNA-templated transcription, initiation
AOD64_RS18535	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AOD64_RS18615	COG1396	sequence-specific DNA binding
AOD64_RS18640	COG0174	glutamine synthetase
AOD64_RS18645	COG0789	Transcriptional regulator
AOD64_RS18650	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AOD64_RS18660	COG2860	membrane
AOD64_RS18665	COG0464	growth
AOD64_RS18695	COG1388	LysM domain
AOD64_RS18695	COG3584	3D domain protein
AOD64_RS18700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOD64_RS18700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOD64_RS18700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOD64_RS18705	COG1105	Belongs to the carbohydrate kinase PfkB family
AOD64_RS18710	COG1349	DNA-binding transcription factor activity
AOD64_RS18720	COG2322	membrane
AOD64_RS18735	COG1113	amino acid transport
AOD64_RS18745	COG1408	metallophosphoesterase
AOD64_RS18750	COG2116	formate transmembrane transporter activity
AOD64_RS18760	COG2217	Heavy metal translocating P-type atpase
AOD64_RS18765	COG2608	mercury ion transmembrane transporter activity
AOD64_RS18770	COG1937	Protein conserved in bacteria
AOD64_RS18780	COG2819	hydrolase of the alpha beta superfamily
AOD64_RS18785	COG1120	ATPase activity
AOD64_RS18790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS18795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS18800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS18810	COG0708	Exodeoxyribonuclease III
AOD64_RS18815	COG2169	Transcriptional regulator
AOD64_RS18820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOD64_RS18825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AOD64_RS18835	COG2364	Membrane
AOD64_RS18850	COG2267	carboxylic ester hydrolase activity
AOD64_RS18855	COG0346	lactoylglutathione lyase activity
AOD64_RS18860	COG5001	Diguanylate cyclase
AOD64_RS18860	COG3300	MHYT domain
AOD64_RS18880	COG1346	cytolysis
AOD64_RS18885	COG1380	Effector of murein hydrolase LrgA
AOD64_RS18890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOD64_RS18895	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD64_RS18895	COG0596	Alpha beta hydrolase
AOD64_RS18900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AOD64_RS18915	COG1404	Belongs to the peptidase S8 family
AOD64_RS18920	COG3773	Cell wall hydrolase
AOD64_RS18925	COG0562	UDP-galactopyranose mutase
AOD64_RS18930	COG1368	sulfuric ester hydrolase activity
AOD64_RS18935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AOD64_RS18945	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AOD64_RS18970	COG1131	(ABC) transporter
AOD64_RS18990	COG4550	Control of competence regulator ComK, YlbF/YmcA
AOD64_RS18995	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOD64_RS19000	COG1013	pyruvate-flavodoxin oxidoreductase activity
AOD64_RS19005	COG0674	pyruvate-flavodoxin oxidoreductase activity
AOD64_RS19005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AOD64_RS19015	COG2359	stage V sporulation protein S
AOD64_RS19020	COG1692	metallophosphoesterase
AOD64_RS19045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOD64_RS19050	COG1426	Protein conserved in bacteria
AOD64_RS19065	COG0300	oxidoreductase activity
AOD64_RS19070	COG0612	Peptidase, M16
AOD64_RS19075	COG0612	Peptidase, M16
AOD64_RS19085	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOD64_RS19090	COG4603	Belongs to the binding-protein-dependent transport system permease family
AOD64_RS19095	COG3845	ABC transporter
AOD64_RS19100	COG1744	ABC transporter substrate-binding protein PnrA-like
AOD64_RS19105	COG2188	Transcriptional regulator
AOD64_RS19110	COG1674	ftsk spoiiie
AOD64_RS19120	COG0740	serine-type endopeptidase activity
AOD64_RS19125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOD64_RS19140	COG0527	aspartate kinase activity
AOD64_RS19145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AOD64_RS19150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOD64_RS19155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOD64_RS19160	COG1873	PFAM PRC-barrel domain
AOD64_RS19165	COG0612	Peptidase, M16
AOD64_RS19170	COG0726	polysaccharide deacetylase
AOD64_RS19185	COG0196	riboflavin kinase activity
AOD64_RS19190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOD64_RS19200	COG1550	Protein conserved in bacteria
AOD64_RS19210	COG1358	cellular component organization or biogenesis
AOD64_RS19215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AOD64_RS19220	COG0195	Participates in both transcription termination and antitermination
AOD64_RS19240	COG0750	zinc metalloprotease
AOD64_RS19250	COG4589	Belongs to the CDS family
AOD64_RS19255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOD64_RS19265	COG0528	UMP kinase activity
AOD64_RS19295	COG4974	Belongs to the 'phage' integrase family
AOD64_RS19305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AOD64_RS19315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AOD64_RS19355	COG1837	Belongs to the UPF0109 family
AOD64_RS19365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOD64_RS19375	COG0552	protein localization to endoplasmic reticulum
AOD64_RS19380	COG1196	nuclear chromosome segregation
AOD64_RS19390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOD64_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS19400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOD64_RS19415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOD64_RS19420	COG1461	Dihydroxyacetone kinase
AOD64_RS19425	COG1302	Protein conserved in bacteria
AOD64_RS19440	COG1564	THIamine pyrophosphokinase
AOD64_RS19445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOD64_RS19450	COG1162	GTPase activity
AOD64_RS19455	COG2815	serine threonine protein kinase
AOD64_RS19455	COG0515	serine threonine protein kinase
AOD64_RS19460	COG0631	protein serine/threonine phosphatase activity
AOD64_RS19470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AOD64_RS19470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AOD64_RS19480	COG0242	peptide deformylase activity
AOD64_RS19485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOD64_RS19490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOD64_RS19510	COG1561	YicC-like family, N-terminal region
AOD64_RS19515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOD64_RS19525	COG0006	proline dipeptidase activity
AOD64_RS19540	COG3069	C4-dicarboxylate transmembrane transporter activity
AOD64_RS19605	COG0564	pseudouridine synthase activity
AOD64_RS19625	COG3599	regulation of cell shape
AOD64_RS19630	COG2302	S4 RNA-binding domain
AOD64_RS19635	COG0762	integral membrane protein
AOD64_RS19645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AOD64_RS19650	COG1496	oxidoreductase activity
AOD64_RS19655	COG1873	PFAM PRC-barrel domain
AOD64_RS19660	COG1191	sigma factor activity
AOD64_RS19665	COG1191	sigma factor activity
AOD64_RS19675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOD64_RS19680	COG0849	cell division
AOD64_RS19685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOD64_RS19690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOD64_RS19700	COG0772	Belongs to the SEDS family
AOD64_RS19715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOD64_RS19720	COG0768	penicillin binding
AOD64_RS19725	COG0768	penicillin binding
AOD64_RS19730	COG4839	cell division protein FtsL
AOD64_RS19745	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AOD64_RS19760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AOD64_RS19765	COG1399	metal-binding, possibly nucleic acid-binding protein
AOD64_RS19815	COG4824	toxin secretion phage lysis holin
AOD64_RS19910	COG1802	Transcriptional regulator
AOD64_RS19910	COG4626	Terminase
AOD64_RS19935	COG0582	viral genome integration into host DNA
AOD64_RS20000	COG0756	dUTP diphosphatase activity
AOD64_RS20010	COG1191	sigma factor activity
AOD64_RS20035	COG1484	DNA-dependent DNA replication
AOD64_RS20065	COG1396	sequence-specific DNA binding
AOD64_RS20075	COG1396	sequence-specific DNA binding
AOD64_RS20090	COG0582	viral genome integration into host DNA
AOD64_RS20100	COG3480	Lon protease (S16) C-terminal proteolytic domain
AOD64_RS20105	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOD64_RS20110	COG3314	Sporulation integral membrane protein YlbJ
AOD64_RS20120	COG0742	ribosomal rna small subunit methyltransferase
AOD64_RS20135	COG3679	Belongs to the UPF0342 family
AOD64_RS20140	COG0406	alpha-ribazole phosphatase activity
AOD64_RS20155	COG2340	Cysteine-rich secretory protein family
AOD64_RS20170	COG3336	cytochrome c oxidase
AOD64_RS20205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AOD64_RS20210	COG0772	Belongs to the SEDS family
AOD64_RS20220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AOD64_RS20225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AOD64_RS20235	COG4896	Protein conserved in bacteria
AOD64_RS20250	COG1217	gtp-binding protein TYPA
AOD64_RS20260	COG0483	inositol monophosphate 1-phosphatase activity
AOD64_RS20280	COG1982	Orn Lys Arg decarboxylase major
AOD64_RS20325	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD64_RS20330	COG0022	dehydrogenase e1 component
AOD64_RS20335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOD64_RS20345	COG0242	peptide deformylase activity
AOD64_RS20350	COG0561	phosphatase activity
AOD64_RS20360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AOD64_RS20365	COG0569	domain protein
AOD64_RS20385	COG0583	DNA-binding transcription factor activity
AOD64_RS20390	COG0517	IMP dehydrogenase activity
AOD64_RS20400	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AOD64_RS20410	COG4703	Protein of unknown function (DUF1797)
AOD64_RS20425	COG2200	EAL domain
AOD64_RS20430	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS20435	COG1408	metallophosphoesterase
AOD64_RS20445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AOD64_RS20485	COG2814	Major facilitator Superfamily
AOD64_RS20505	COG3209	COG3209 Rhs family protein
AOD64_RS20515	COG2205	protein histidine kinase activity
AOD64_RS20525	COG0436	Aminotransferase
AOD64_RS20530	COG1609	Transcriptional regulator
AOD64_RS20535	COG3833	ABC-type maltose transport systems, permease component
AOD64_RS20540	COG1175	transmembrane transport
AOD64_RS20545	COG2182	Extracellular solute-binding protein
AOD64_RS20555	COG0366	Alpha amylase catalytic
AOD64_RS20560	COG3842	ATPase activity
AOD64_RS20600	COG0183	Belongs to the thiolase family
AOD64_RS20640	COG1695	Transcriptional regulator
AOD64_RS20645	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS20655	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AOD64_RS20665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOD64_RS20670	COG0436	Aminotransferase
AOD64_RS20690	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AOD64_RS20710	COG2199	diguanylate cyclase activity
AOD64_RS20715	COG0778	Nitroreductase
AOD64_RS20740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AOD64_RS20740	COG2190	(PTS) system
AOD64_RS20740	COG1263	PTS System
AOD64_RS20745	COG3711	transcriptional antiterminator
AOD64_RS20755	COG2188	Transcriptional regulator
AOD64_RS20765	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AOD64_RS20795	COG1547	Domain of unknown function (DUF309)
AOD64_RS20800	COG0456	acetyltransferase
AOD64_RS20810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOD64_RS20815	COG4086	secreted protein
AOD64_RS20820	COG0561	phosphatase activity
AOD64_RS20825	COG0697	spore germination
AOD64_RS20840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD64_RS20865	COG0733	neurotransmitter:sodium symporter activity
AOD64_RS20885	COG1686	Belongs to the peptidase S11 family
AOD64_RS20890	COG1725	Transcriptional regulator
AOD64_RS20895	COG1131	(ABC) transporter
AOD64_RS20915	COG1846	Transcriptional regulator
AOD64_RS20930	COG0598	Magnesium transport protein CorA
AOD64_RS20955	COG4974	Belongs to the 'phage' integrase family
AOD64_RS20965	COG0735	belongs to the Fur family
AOD64_RS20970	COG1300	Membrane
AOD64_RS20990	COG0667	Aldo Keto reductase
AOD64_RS20995	COG0656	L-ascorbic acid biosynthetic process
AOD64_RS21000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOD64_RS21000	COG0456	acetyltransferase
AOD64_RS21010	COG4085	toxin activity
AOD64_RS21010	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS21010	COG1525	nuclease
AOD64_RS21020	COG0596	Alpha beta hydrolase
AOD64_RS21025	COG2056	Na+-H+ antiporter family
AOD64_RS21030	COG1609	Transcriptional regulator
AOD64_RS21035	COG0456	acetyltransferase
AOD64_RS21040	COG1073	alpha beta
AOD64_RS21055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOD64_RS21055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOD64_RS21060	COG0307	riboflavin synthase, alpha
AOD64_RS21085	COG4106	trans-aconitate 2-methyltransferase activity
AOD64_RS21090	COG2226	methyltransferase
AOD64_RS21090	COG1073	alpha beta
AOD64_RS21105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AOD64_RS21115	COG1757	Na H antiporter
AOD64_RS21120	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS21130	COG1522	sequence-specific DNA binding
AOD64_RS21150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOD64_RS21160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOD64_RS21175	COG0300	oxidoreductase activity
AOD64_RS21180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS21190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD64_RS21195	COG1760	l-serine dehydratase
AOD64_RS21200	COG1760	l-serine dehydratase
AOD64_RS21220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOD64_RS21230	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOD64_RS21235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS21250	COG1376	ErfK ybiS ycfS ynhG family protein
AOD64_RS21255	COG4129	membrane
AOD64_RS21260	COG1126	abc transporter atp-binding protein
AOD64_RS21265	COG0765	amino acid transport
AOD64_RS21270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOD64_RS21285	COG2816	NAD+ diphosphatase activity
AOD64_RS21290	COG0772	Belongs to the SEDS family
AOD64_RS21300	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOD64_RS21305	COG0022	dehydrogenase e1 component
AOD64_RS21310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOD64_RS21315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOD64_RS21330	COG0280	phosphate acetyltransferase
AOD64_RS21340	COG3290	protein histidine kinase activity
AOD64_RS21340	COG3829	transcription factor binding
AOD64_RS21350	COG0584	glycerophosphoryl diester phosphodiesterase
AOD64_RS21355	COG3093	addiction module antidote protein HigA
AOD64_RS21365	COG0745	RESPONSE REGULATOR receiver
AOD64_RS21375	COG0750	zinc metalloprotease
AOD64_RS21380	COG0497	DNA recombination
AOD64_RS21390	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AOD64_RS21400	COG0142	geranyltranstransferase activity
AOD64_RS21425	COG1302	Protein conserved in bacteria
AOD64_RS21430	COG0439	Biotin carboxylase
AOD64_RS21435	COG0511	ligase activity, forming carbon-carbon bonds
AOD64_RS21480	COG3854	ATPases associated with a variety of cellular activities
AOD64_RS21505	COG0006	proline dipeptidase activity
AOD64_RS21520	COG3872	metal-dependent enzyme
AOD64_RS21530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOD64_RS21550	COG0095	Lipoate-protein ligase
AOD64_RS21555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD64_RS21560	COG1609	Transcriptional regulator
AOD64_RS21570	COG2076	Multidrug Resistance protein
AOD64_RS21575	COG2076	Multidrug Resistance protein
AOD64_RS21615	COG1131	(ABC) transporter
AOD64_RS21620	COG1725	Transcriptional regulator
AOD64_RS21650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOD64_RS21705	COG4970	Tfp pilus assembly protein FimT
AOD64_RS21715	COG1459	type II secretion system
AOD64_RS21720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOD64_RS21770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AOD64_RS21775	COG0646	methionine synthase
AOD64_RS21775	COG1410	methionine synthase
AOD64_RS21780	COG0646	methionine synthase
AOD64_RS21780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOD64_RS21785	COG0626	cystathionine gamma-synthase activity
AOD64_RS21790	COG0626	cystathionine gamma-synthase activity
AOD64_RS21815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS21825	COG1940	carbohydrate kinase activity
AOD64_RS21830	COG4483	Protein conserved in bacteria
AOD64_RS21835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOD64_RS21840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AOD64_RS21845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOD64_RS21850	COG0704	Plays a role in the regulation of phosphate uptake
AOD64_RS21860	COG0581	inorganic phosphate transmembrane transporter activity
AOD64_RS21865	COG0573	inorganic phosphate transmembrane transporter activity
AOD64_RS21870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOD64_RS21875	COG0768	penicillin binding
AOD64_RS21880	COG0477	Major facilitator Superfamily
AOD64_RS21885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOD64_RS21910	COG0735	belongs to the Fur family
AOD64_RS21915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOD64_RS21920	COG1121	(ABC) transporter
AOD64_RS21925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS21955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOD64_RS21960	COG2384	SAM-dependent methyltransferase
AOD64_RS21965	COG2010	Cytochrome c
AOD64_RS21970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AOD64_RS21975	COG0358	DNA primase activity
AOD64_RS21995	COG0517	IMP dehydrogenase activity
AOD64_RS22010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOD64_RS22015	COG0295	cytidine deaminase activity
AOD64_RS22020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AOD64_RS22030	COG1480	7TM receptor with intracellular HD hydrolase
AOD64_RS22035	COG1702	phosphate starvation-inducible protein PhoH
AOD64_RS22055	COG1610	YqeY-like protein
AOD64_RS22060	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AOD64_RS22065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AOD64_RS22070	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOD64_RS22100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOD64_RS22105	COG1733	regulation of RNA biosynthetic process
AOD64_RS22130	COG1466	dna polymerase III delta subunit
AOD64_RS22140	COG0658	competence protein
AOD64_RS22140	COG2333	competence protein COMEC
AOD64_RS22145	COG2131	deaminase
AOD64_RS22150	COG1555	photosystem II stabilization
AOD64_RS22150	COG1596	polysaccharide export
AOD64_RS22155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AOD64_RS22160	COG2226	methyltransferase
AOD64_RS22165	COG0799	negative regulation of ribosome biogenesis
AOD64_RS22170	COG1713	HD superfamily hydrolase involved in NAD metabolism
AOD64_RS22180	COG1534	Rna-binding protein
AOD64_RS22190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AOD64_RS22195	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AOD64_RS22220	COG1595	DNA-templated transcription, initiation
AOD64_RS22230	COG0778	Nitroreductase
AOD64_RS22235	COG2357	RelA SpoT domain protein
AOD64_RS22245	COG1785	Belongs to the alkaline phosphatase family
AOD64_RS22255	COG2267	carboxylic ester hydrolase activity
AOD64_RS22290	COG1404	Belongs to the peptidase S8 family
AOD64_RS22295	COG3186	Phenylalanine-4-hydroxylase
AOD64_RS22305	COG2514	catechol 2,3-dioxygenase activity
AOD64_RS22310	COG2514	catechol 2,3-dioxygenase activity
AOD64_RS22315	COG2259	Doxx family
AOD64_RS22355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS22365	COG1012	belongs to the aldehyde dehydrogenase family
AOD64_RS22365	COG1454	alcohol dehydrogenase
AOD64_RS22370	COG0626	cystathionine gamma-synthase activity
AOD64_RS22375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOD64_RS22400	COG0768	penicillin binding
AOD64_RS22415	COG0826	peptidase U32
AOD64_RS22420	COG0826	peptidase U32
AOD64_RS22425	COG4122	O-methyltransferase activity
AOD64_RS22430	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOD64_RS22450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AOD64_RS22460	COG0628	permease
AOD64_RS22480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOD64_RS22490	COG0482	sulfurtransferase activity
AOD64_RS22495	COG1104	cysteine desulfurase activity
AOD64_RS22500	COG1959	2 iron, 2 sulfur cluster binding
AOD64_RS22505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOD64_RS22515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOD64_RS22540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOD64_RS22550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AOD64_RS22550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOD64_RS22555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AOD64_RS22560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOD64_RS22560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOD64_RS22570	COG2244	polysaccharide biosynthetic process
AOD64_RS22575	COG2323	membrane
AOD64_RS22585	COG1862	Preprotein translocase
AOD64_RS22615	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AOD64_RS22625	COG0697	spore germination
AOD64_RS22630	COG0697	spore germination
AOD64_RS22635	COG0640	Transcriptional regulator
AOD64_RS22660	COG0157	Belongs to the NadC ModD family
AOD64_RS22665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AOD64_RS22670	COG1104	cysteine desulfurase activity
AOD64_RS22675	COG1827	regulation of RNA biosynthetic process
AOD64_RS22680	COG2258	MOSC domain
AOD64_RS22685	COG0077	Prephenate dehydratase
AOD64_RS22690	COG0577	efflux transmembrane transporter activity
AOD64_RS22695	COG0577	efflux transmembrane transporter activity
AOD64_RS22700	COG1136	(ABC) transporter
AOD64_RS22705	COG5002	protein histidine kinase activity
AOD64_RS22715	COG0745	RESPONSE REGULATOR receiver
AOD64_RS22720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AOD64_RS22725	COG3290	protein histidine kinase activity
AOD64_RS22735	COG2868	ribosomal protein
AOD64_RS22745	COG1530	ribonuclease E activity
AOD64_RS22750	COG1994	Peptidase M50
AOD64_RS22755	COG0739	heme binding
AOD64_RS22760	COG2894	cell division
AOD64_RS22780	COG1077	Cell shape determining protein MreB Mrl
AOD64_RS22800	COG0285	dihydrofolate synthase activity
AOD64_RS22805	COG0525	valine-tRNA ligase activity
AOD64_RS22815	COG1388	LysM domain
AOD64_RS22825	COG0113	porphobilinogen synthase activity
AOD64_RS22830	COG1587	Uroporphyrinogen-III synthase
AOD64_RS22840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AOD64_RS22850	COG1846	Transcriptional regulator
AOD64_RS22855	COG1764	response to oxidative stress
AOD64_RS22870	COG0470	DNA polymerase III
AOD64_RS22870	COG1067	ATP-dependent peptidase activity
AOD64_RS22925	COG0622	Phosphoesterase
AOD64_RS22940	COG5401	PFAM Sporulation and spore germination
AOD64_RS22960	COG1309	transcriptional regulator
AOD64_RS22975	COG2197	response regulator
AOD64_RS22980	COG2233	PERMEase
AOD64_RS22990	COG0402	S-adenosylhomocysteine deaminase activity
AOD64_RS22995	COG0402	S-adenosylhomocysteine deaminase activity
AOD64_RS23005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOD64_RS23015	COG0444	Belongs to the ABC transporter superfamily
AOD64_RS23020	COG4608	Belongs to the ABC transporter superfamily
AOD64_RS23025	COG3275	phosphorelay sensor kinase activity
AOD64_RS23030	COG3279	Response regulator of the LytR AlgR family
AOD64_RS23045	COG1983	PspC domain protein
AOD64_RS23050	COG1396	sequence-specific DNA binding
AOD64_RS23055	COG0697	spore germination
AOD64_RS23065	COG1959	2 iron, 2 sulfur cluster binding
AOD64_RS23070	COG1668	transmembrane transport
AOD64_RS23075	COG4152	abc transporter atp-binding protein
AOD64_RS23080	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AOD64_RS23090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AOD64_RS23095	COG1876	peptidase activity
AOD64_RS23100	COG0824	Thioesterase
AOD64_RS23105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOD64_RS23110	COG1053	succinate dehydrogenase
AOD64_RS23115	COG2009	succinate dehydrogenase
AOD64_RS23120	COG1719	4-vinyl reductase, 4VR
AOD64_RS23130	COG3118	belongs to the thioredoxin family
AOD64_RS23135	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AOD64_RS23140	COG2086	electron transfer activity
AOD64_RS23145	COG1024	Enoyl-CoA hydratase
AOD64_RS23150	COG1309	transcriptional regulator
AOD64_RS23155	COG0318	PFAM AMP-dependent synthetase and ligase
AOD64_RS23175	COG2318	DinB family
AOD64_RS23205	COG1131	(ABC) transporter
AOD64_RS23210	COG2205	protein histidine kinase activity
AOD64_RS23215	COG0745	RESPONSE REGULATOR receiver
AOD64_RS23225	COG4895	conserved protein (DUF2196)
AOD64_RS23230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AOD64_RS23245	COG4509	Sortase family
AOD64_RS23250	COG1120	ATPase activity
AOD64_RS23265	COG5386	Cell surface protein
AOD64_RS23275	COG5386	Cell surface protein
AOD64_RS23280	COG1114	Component of the transport system for branched-chain amino acids
AOD64_RS23285	COG1187	pseudouridine synthase activity
AOD64_RS23300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AOD64_RS23300	COG1796	DNA polymerase
AOD64_RS23305	COG1286	toxin biosynthetic process
AOD64_RS23350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOD64_RS23360	COG1418	mRNA catabolic process
AOD64_RS23385	COG2814	Major facilitator Superfamily
AOD64_RS23390	COG1566	PFAM secretion protein HlyD family protein
AOD64_RS23395	COG1309	transcriptional regulator
AOD64_RS23400	COG1363	Peptidase, m42
AOD64_RS23425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AOD64_RS23435	COG1484	DNA-dependent DNA replication
AOD64_RS23440	COG3611	Membrane attachment protein
AOD64_RS23450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AOD64_RS23455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOD64_RS23460	COG0237	dephospho-CoA kinase activity
AOD64_RS23465	COG1971	Probably functions as a manganese efflux pump
AOD64_RS23475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOD64_RS23475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AOD64_RS23480	COG5002	protein histidine kinase activity
AOD64_RS23485	COG0745	RESPONSE REGULATOR receiver
AOD64_RS23505	COG0538	isocitrate dehydrogenase activity
AOD64_RS23510	COG0372	Belongs to the citrate synthase family
AOD64_RS23525	COG0628	permease
AOD64_RS23530	COG3030	protein affecting phage T7 exclusion by the F plasmid
AOD64_RS23555	COG1725	Transcriptional regulator
AOD64_RS23560	COG0281	malic enzyme
AOD64_RS23565	COG0587	DNA-directed DNA polymerase activity
AOD64_RS23580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AOD64_RS23600	COG4109	DRTGG domain
AOD64_RS23615	COG0006	proline dipeptidase activity
AOD64_RS23650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS23655	COG0662	Cupin 2, conserved barrel domain protein
AOD64_RS23665	COG1476	TRANSCRIPTIONal
AOD64_RS23680	COG1028	Short-chain dehydrogenase reductase Sdr
AOD64_RS23685	COG0589	response to stress
AOD64_RS23725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS23745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOD64_RS23750	COG0827	DNA restriction-modification system
AOD64_RS23755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AOD64_RS23760	COG3874	Sporulation protein YtfJ
AOD64_RS23775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AOD64_RS23785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOD64_RS23800	COG1104	cysteine desulfurase activity
AOD64_RS23810	COG0583	DNA-binding transcription factor activity
AOD64_RS23815	COG0697	spore germination
AOD64_RS23825	COG1956	GAF domain-containing protein
AOD64_RS23830	COG0626	cystathionine gamma-synthase activity
AOD64_RS23860	COG1595	DNA-templated transcription, initiation
AOD64_RS23870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOD64_RS23875	COG0454	-acetyltransferase
AOD64_RS23880	COG0517	IMP dehydrogenase activity
AOD64_RS23885	COG0123	including yeast histone deacetylase and acetoin utilization protein
AOD64_RS23895	COG0745	RESPONSE REGULATOR receiver
AOD64_RS23905	COG0666	response to abiotic stimulus
AOD64_RS23940	COG1609	Transcriptional regulator
AOD64_RS23950	COG4851	CamS sex pheromone cAM373 precursor
AOD64_RS23955	COG3118	belongs to the thioredoxin family
AOD64_RS23965	COG2309	aminopeptidase activity
AOD64_RS23985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS24000	COG1674	ftsk spoiiie
AOD64_RS24010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOD64_RS24015	COG4848	Belongs to the UPF0354 family
AOD64_RS24020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD64_RS24025	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AOD64_RS24030	COG1363	Peptidase, m42
AOD64_RS24040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS24055	COG0510	thiamine kinase activity
AOD64_RS24060	COG1523	belongs to the glycosyl hydrolase 13 family
AOD64_RS24075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD64_RS24080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AOD64_RS24085	COG1349	DNA-binding transcription factor activity
AOD64_RS24090	COG1187	pseudouridine synthase activity
AOD64_RS24095	COG2244	polysaccharide biosynthetic process
AOD64_RS24100	COG2081	HI0933 family
AOD64_RS24105	COG2814	Major facilitator Superfamily
AOD64_RS24115	COG3832	glyoxalase III activity
AOD64_RS24135	COG1329	Transcriptional regulator
AOD64_RS24145	COG4975	Glucose uptake
AOD64_RS24160	COG0314	molybdopterin synthase activity
AOD64_RS24165	COG1763	Mo-molybdopterin cofactor biosynthetic process
AOD64_RS24170	COG0303	'Molybdopterin
AOD64_RS24180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AOD64_RS24205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AOD64_RS24215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOD64_RS24260	COG2814	Major facilitator Superfamily
AOD64_RS24265	COG0475	glutathione-regulated potassium exporter activity
AOD64_RS24270	COG0490	domain, Protein
AOD64_RS24275	COG0582	viral genome integration into host DNA
AOD64_RS24285	COG1136	(ABC) transporter
AOD64_RS24305	COG1242	4 iron, 4 sulfur cluster binding
AOD64_RS24310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AOD64_RS24315	COG1131	(ABC) transporter
AOD64_RS24325	COG1794	racemase activity, acting on amino acids and derivatives
AOD64_RS24345	COG2267	carboxylic ester hydrolase activity
AOD64_RS24350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOD64_RS24355	COG0671	phosphoesterase, PA-phosphatase related
AOD64_RS24360	COG0438	transferase activity, transferring glycosyl groups
AOD64_RS24370	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOD64_RS24425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOD64_RS24430	COG5002	protein histidine kinase activity
AOD64_RS24435	COG4191	Histidine kinase
AOD64_RS24440	COG2267	carboxylic ester hydrolase activity
AOD64_RS24460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOD64_RS24465	COG1116	anion transmembrane transporter activity
AOD64_RS24470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOD64_RS24495	COG0494	nUDIX hydrolase
AOD64_RS24525	COG0288	reversible hydration of carbon dioxide
AOD64_RS24530	COG1271	oxidase subunit
AOD64_RS24535	COG1294	oxidase, subunit
AOD64_RS24555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS24580	COG1842	Phage shock protein A
AOD64_RS24615	COG5002	protein histidine kinase activity
AOD64_RS24620	COG0745	RESPONSE REGULATOR receiver
AOD64_RS24650	COG1597	lipid kinase activity
AOD64_RS24685	COG0586	Pfam SNARE associated Golgi protein
AOD64_RS24695	COG0577	efflux transmembrane transporter activity
AOD64_RS24700	COG1136	(ABC) transporter
AOD64_RS24705	COG2207	Transcriptional regulator
AOD64_RS24705	COG3708	Transcriptional regulator
AOD64_RS24710	COG0745	RESPONSE REGULATOR receiver
AOD64_RS24715	COG2205	protein histidine kinase activity
AOD64_RS24720	COG0577	efflux transmembrane transporter activity
AOD64_RS24730	COG0577	efflux transmembrane transporter activity
AOD64_RS24735	COG1136	(ABC) transporter
AOD64_RS24755	COG2188	Transcriptional regulator
AOD64_RS24775	COG3964	amidohydrolase
AOD64_RS24805	COG4948	Mandelate Racemase Muconate Lactonizing
AOD64_RS24815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AOD64_RS24820	COG0596	Alpha beta hydrolase
AOD64_RS24825	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AOD64_RS24830	COG1169	isochorismate synthase
AOD64_RS24835	COG1575	Belongs to the MenA family. Type 1 subfamily
AOD64_RS24840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOD64_RS24865	COG0058	SHG alpha-glucan phosphorylase activity
AOD64_RS24870	COG0297	glycogen (starch) synthase activity
AOD64_RS24875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AOD64_RS24985	COG0544	peptidyl-prolyl cis-trans isomerase activity
AOD64_RS25020	COG1285	pathogenesis
AOD64_RS25025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOD64_RS25035	COG0166	Belongs to the GPI family
AOD64_RS25045	COG2155	Conserved Protein
AOD64_RS25050	COG1098	S1 RNA binding domain
AOD64_RS25055	COG0436	Aminotransferase
AOD64_RS25060	COG1522	sequence-specific DNA binding
AOD64_RS25065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AOD64_RS25070	COG2267	carboxylic ester hydrolase activity
AOD64_RS25080	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AOD64_RS25100	COG5018	Exonuclease
AOD64_RS25105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOD64_RS25125	COG2050	protein possibly involved in aromatic compounds catabolism
AOD64_RS25135	COG1268	BioY protein
AOD64_RS25145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOD64_RS25150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOD64_RS25165	COG3584	3D domain protein
AOD64_RS25180	COG1252	NADH dehydrogenase
AOD64_RS25195	COG3708	Transcriptional regulator
AOD64_RS25210	COG1683	Conserved Protein
AOD64_RS25230	COG0316	Belongs to the HesB IscA family
AOD64_RS25245	COG1252	NADH dehydrogenase
AOD64_RS25260	COG0390	transport system, permease component
AOD64_RS25265	COG2824	Alkylphosphonate utilization operon protein PhnA
AOD64_RS25305	COG4837	Protein of unknown function (DUF1462)
AOD64_RS25310	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AOD64_RS25320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOD64_RS25325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOD64_RS25340	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOD64_RS25345	COG0647	UMP catabolic process
AOD64_RS25355	COG2445	Protein of unknown function DUF86
AOD64_RS25360	COG1494	fructose-1,6-bisphosphatase
AOD64_RS25380	COG4470	Protein conserved in bacteria
AOD64_RS25390	COG0789	Transcriptional regulator
AOD64_RS25395	COG4377	Putative membrane peptidase family (DUF2324)
AOD64_RS25420	COG0739	heme binding
AOD64_RS25430	COG3377	Domain of unknown function (DUF1805)
AOD64_RS25435	COG0737	Belongs to the 5'-nucleotidase family
AOD64_RS25445	COG1695	Transcriptional regulator
AOD64_RS25460	COG0719	Fe-S assembly protein
AOD64_RS25465	COG0822	iron-sulfur transferase activity
AOD64_RS25470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOD64_RS25475	COG0719	Fe-S assembly protein
AOD64_RS25480	COG0396	ATPase activity
AOD64_RS25485	COG1464	Belongs to the NlpA lipoprotein family
AOD64_RS25490	COG1464	Belongs to the NlpA lipoprotein family
AOD64_RS25495	COG2011	ABC-type metal ion transport system permease component
AOD64_RS25500	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOD64_RS25515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AOD64_RS25520	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AOD64_RS25530	COG1393	Belongs to the ArsC family
AOD64_RS25580	COG0039	L-malate dehydrogenase activity
AOD64_RS25600	COG1309	transcriptional regulator
AOD64_RS25605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOD64_RS25610	COG1960	acyl-CoA dehydrogenase activity
AOD64_RS25615	COG0183	Belongs to the thiolase family
AOD64_RS25620	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOD64_RS25620	COG1024	Enoyl-CoA hydratase
AOD64_RS25630	COG1686	Belongs to the peptidase S11 family
AOD64_RS25645	COG0011	TIGRFAM Protein of
AOD64_RS25650	COG0840	transmembrane signaling receptor activity
AOD64_RS25670	COG2814	Major facilitator Superfamily
AOD64_RS25675	COG0531	amino acid
AOD64_RS25685	COG0706	membrane insertase activity
AOD64_RS25695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AOD64_RS25730	COG0586	Pfam SNARE associated Golgi protein
AOD64_RS25740	COG1376	ErfK ybiS ycfS ynhG family protein
AOD64_RS25745	COG0745	RESPONSE REGULATOR receiver
AOD64_RS25750	COG5002	protein histidine kinase activity
AOD64_RS25775	COG2151	metal-sulfur cluster biosynthetic enzyme
AOD64_RS25780	COG3227	Zinc metalloprotease (Elastase)
AOD64_RS25785	COG1741	Belongs to the pirin family
AOD64_RS25800	COG0475	glutathione-regulated potassium exporter activity
AOD64_RS25805	COG0490	domain, Protein
AOD64_RS25815	COG1115	amino acid carrier protein
AOD64_RS25820	COG0783	Belongs to the Dps family
AOD64_RS25835	COG1611	Belongs to the LOG family
AOD64_RS25850	COG2311	Membrane
AOD64_RS25860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS25865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS25870	COG1115	amino acid carrier protein
AOD64_RS25875	COG1115	amino acid carrier protein
AOD64_RS25880	COG2910	NAD(P)H-binding
AOD64_RS25895	COG0656	L-ascorbic acid biosynthetic process
AOD64_RS25900	COG2814	Major facilitator Superfamily
AOD64_RS25905	COG1733	regulation of RNA biosynthetic process
AOD64_RS25915	COG1252	NADH dehydrogenase
AOD64_RS25920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOD64_RS25925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AOD64_RS25935	COG3290	protein histidine kinase activity
AOD64_RS25935	COG0840	transmembrane signaling receptor activity
AOD64_RS25945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOD64_RS25950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AOD64_RS25965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AOD64_RS26020	COG0557	exoribonuclease II activity
AOD64_RS26025	COG1647	Serine aminopeptidase, S33
AOD64_RS26030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AOD64_RS26035	COG1346	cytolysis
AOD64_RS26135	COG4695	Portal protein
AOD64_RS26160	COG4974	Belongs to the 'phage' integrase family
AOD64_RS26170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOD64_RS26175	COG0149	triose-phosphate isomerase activity
AOD64_RS26185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOD64_RS26200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AOD64_RS26225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AOD64_RS26240	COG2323	membrane
AOD64_RS26245	COG0740	serine-type endopeptidase activity
AOD64_RS26250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOD64_RS26260	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AOD64_RS26270	COG1051	belongs to the nudix hydrolase family
AOD64_RS26280	COG0492	ferredoxin-NADP+ reductase activity
AOD64_RS26285	COG0457	Tetratricopeptide repeat
AOD64_RS26290	COG0110	maltose O-acetyltransferase activity
AOD64_RS26310	COG1950	PFAM Membrane protein of
AOD64_RS26320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOD64_RS26325	COG0556	nucleotide-excision repair
AOD64_RS26345	COG0789	Transcriptional regulator
AOD64_RS26370	COG2855	membrane
AOD64_RS26375	COG0583	DNA-binding transcription factor activity
AOD64_RS26385	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOD64_RS26390	COG0488	(ABC) transporter
AOD64_RS26400	COG1132	(ABC) transporter
AOD64_RS26405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOD64_RS26410	COG3409	Peptidoglycan-binding domain 1 protein
AOD64_RS26410	COG0793	Belongs to the peptidase S41A family
AOD64_RS26415	COG2177	Part of the ABC transporter FtsEX involved in
AOD64_RS26420	COG2884	Cell division ATP-binding protein ftsE
AOD64_RS26435	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AOD64_RS26440	COG0653	protein targeting
AOD64_RS26445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AOD64_RS26450	COG1278	Cold shock
AOD64_RS26455	COG1040	competence protein
AOD64_RS26460	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AOD64_RS26465	COG0791	NLP P60 protein
AOD64_RS26465	COG1388	LysM domain
AOD64_RS26470	COG1733	regulation of RNA biosynthetic process
AOD64_RS26480	COG1307	EDD domain protein, DegV family
AOD64_RS26485	COG1739	Uncharacterized protein family UPF0029
AOD64_RS26490	COG1316	TRANSCRIPTIONal
AOD64_RS26495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AOD64_RS26500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AOD64_RS26505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AOD64_RS26515	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AOD64_RS26515	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AOD64_RS26530	COG3394	polysaccharide catabolic process
AOD64_RS26535	COG1486	melibiose metabolic process
AOD64_RS26540	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOD64_RS26545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOD64_RS26555	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AOD64_RS26560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AOD64_RS26565	COG1447	Phosphotransferase system cellobiose-specific component IIA
AOD64_RS26575	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AOD64_RS26580	COG1301	dicarboxylic acid transport
AOD64_RS26590	COG0346	lactoylglutathione lyase activity
AOD64_RS26595	COG1511	domain protein
AOD64_RS26600	COG0583	DNA-binding transcription factor activity
AOD64_RS26605	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AOD64_RS26625	COG1271	oxidase subunit
AOD64_RS26630	COG1294	oxidase, subunit
AOD64_RS26635	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AOD64_RS26645	COG1620	l-lactate permease
AOD64_RS26655	COG2389	metal-binding protein
AOD64_RS26665	COG1368	sulfuric ester hydrolase activity
AOD64_RS26680	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AOD64_RS26700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOD64_RS26705	COG1388	LysM domain
AOD64_RS26705	COG3584	3D domain protein
AOD64_RS26730	COG4715	Zinc finger, swim domain protein
AOD64_RS26735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AOD64_RS26775	COG0577	efflux transmembrane transporter activity
AOD64_RS26780	COG1136	(ABC) transporter
AOD64_RS26815	COG5002	protein histidine kinase activity
AOD64_RS26820	COG0745	RESPONSE REGULATOR receiver
AOD64_RS26825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOD64_RS26840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AOD64_RS26845	COG1134	teichoic acid transport
AOD64_RS26850	COG1682	transport, permease protein
AOD64_RS26855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOD64_RS26900	COG1609	Transcriptional regulator
AOD64_RS26915	COG0739	heme binding
AOD64_RS26930	COG3279	Response regulator of the LytR AlgR family
AOD64_RS26935	COG4555	ABC transporter
AOD64_RS26940	COG2385	sporulation resulting in formation of a cellular spore
AOD64_RS26955	COG4836	Membrane
AOD64_RS26960	COG1007	ATP synthesis coupled electron transport
AOD64_RS26965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOD64_RS26970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOD64_RS26980	COG0839	Belongs to the complex I subunit 6 family
AOD64_RS26995	COG0649	NAD binding
AOD64_RS27000	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOD64_RS27015	COG5001	Diguanylate cyclase
AOD64_RS27015	COG3300	MHYT domain
AOD64_RS27065	COG0356	it plays a direct role in the translocation of protons across the membrane
AOD64_RS27100	COG0698	ribose 5-phosphate isomerase
AOD64_RS27110	COG2190	(PTS) system
AOD64_RS27115	COG2259	Doxx family
AOD64_RS27120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOD64_RS27135	COG0009	L-threonylcarbamoyladenylate synthase
AOD64_RS27150	COG2890	protein-(glutamine-N5) methyltransferase activity
AOD64_RS27170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AOD64_RS27175	COG1494	fructose-1,6-bisphosphatase
AOD64_RS27195	COG4821	SIS domain
AOD64_RS27205	COG3343	RNA polymerase activity
AOD64_RS27215	COG1960	acyl-CoA dehydrogenase activity
AOD64_RS27220	COG1960	acyl-CoA dehydrogenase activity
AOD64_RS27225	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOD64_RS27230	COG0183	Belongs to the thiolase family
AOD64_RS27235	COG2181	nitrate reductase activity
AOD64_RS27235	COG0247	lactate metabolic process
AOD64_RS27240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOD64_RS27250	COG3300	MHYT domain
AOD64_RS27250	COG5001	Diguanylate cyclase
AOD64_RS27265	COG2197	response regulator
AOD64_RS27270	COG4585	Histidine kinase
AOD64_RS27275	COG0842	Transport permease protein
AOD64_RS27280	COG1131	(ABC) transporter
AOD64_RS27285	COG0024	Methionine aminopeptidase
AOD64_RS27305	COG2234	aminopeptidase activity
AOD64_RS27325	COG1595	DNA-templated transcription, initiation
AOD64_RS27330	COG0018	arginyl-trna synthetase
AOD64_RS27335	COG4506	Protein conserved in bacteria
AOD64_RS27340	COG1619	proteins homologs of microcin C7 resistance protein MccF
AOD64_RS27355	COG0010	Belongs to the arginase family
AOD64_RS27365	COG2814	Major facilitator Superfamily
AOD64_RS27370	COG0789	Transcriptional regulator
AOD64_RS27375	COG0584	glycerophosphoryl diester phosphodiesterase
AOD64_RS27380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOD64_RS27390	COG1994	Peptidase M50
AOD64_RS27400	COG1078	dGTPase activity
AOD64_RS27405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AOD64_RS27410	COG1120	ATPase activity
AOD64_RS27415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS27420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS27425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOD64_RS27445	COG0095	Lipoate-protein ligase
AOD64_RS27450	COG0280	phosphate acetyltransferase
AOD64_RS27465	COG3773	Cell wall hydrolase
AOD64_RS27475	COG2363	Small membrane protein
AOD64_RS27490	COG2233	PERMEase
AOD64_RS27495	COG0561	phosphatase activity
AOD64_RS27500	COG2814	Major facilitator Superfamily
AOD64_RS27510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AOD64_RS27515	COG1131	(ABC) transporter
AOD64_RS27520	COG2755	lipolytic protein G-D-S-L family
AOD64_RS27525	COG1609	Transcriptional regulator
AOD64_RS27535	COG0460	homoserine dehydrogenase
AOD64_RS27545	COG2873	o-acetylhomoserine
AOD64_RS27555	COG1011	Hydrolase
AOD64_RS27560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOD64_RS27570	COG2197	response regulator
AOD64_RS27580	COG0351	phosphomethylpyrimidine kinase
AOD64_RS27585	COG3706	GGDEF domain
AOD64_RS27590	COG2879	small protein
AOD64_RS27595	COG1966	Carbon starvation protein
AOD64_RS27600	COG3279	Response regulator of the LytR AlgR family
AOD64_RS27605	COG0477	Major facilitator Superfamily
AOD64_RS27630	COG0840	transmembrane signaling receptor activity
AOD64_RS27640	COG1607	acyl-coa hydrolase
AOD64_RS27655	COG0488	(ABC) transporter
AOD64_RS27685	COG0463	Glycosyl transferase, family 2
AOD64_RS27690	COG1309	transcriptional regulator
AOD64_RS27695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOD64_RS27700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOD64_RS27700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AOD64_RS27705	COG0628	permease
AOD64_RS27720	COG3279	Response regulator of the LytR AlgR family
AOD64_RS27725	COG3275	phosphorelay sensor kinase activity
AOD64_RS27730	COG2814	Major facilitator Superfamily
AOD64_RS27735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOD64_RS27740	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AOD64_RS27745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOD64_RS27765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOD64_RS27770	COG1272	protein, Hemolysin III
AOD64_RS27790	COG0516	GMP reductase activity
AOD64_RS27795	COG1164	Oligoendopeptidase f
AOD64_RS27815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOD64_RS27820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AOD64_RS27825	COG4853	Protein conserved in bacteria
AOD64_RS27830	COG4863	YycH protein
AOD64_RS27835	COG5002	protein histidine kinase activity
AOD64_RS27840	COG0745	RESPONSE REGULATOR receiver
AOD64_RS27870	COG0305	Participates in initiation and elongation during chromosome replication
AOD64_RS27880	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AOD64_RS27885	COG4241	membrane
AOD64_RS27895	COG0629	single-stranded DNA binding
AOD64_RS27905	COG0012	GTP binding
AOD64_RS27910	COG4481	Protein conserved in bacteria
AOD64_RS27915	COG0668	transmembrane transport
AOD64_RS27925	COG1475	DNA binding
AOD64_RS27930	COG1192	Involved in chromosome partitioning
AOD64_RS27955	COG1847	R3H domain protein
AOD64_RS27960	COG0706	membrane insertase activity
AOD64_RS27970	COG0230	Belongs to the bacterial ribosomal protein bL34 family