locus-tag	class	description
C6N15_RS00010	COG0592	DNA-directed DNA polymerase activity
C6N15_RS00015	COG2501	S4 domain
C6N15_RS00025	COG0187	DNA topoisomerase II activity
C6N15_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6N15_RS00065	COG0517	IMP dehydrogenase activity
C6N15_RS00065	COG0516	GMP reductase activity
C6N15_RS00070	COG1686	Belongs to the peptidase S11 family
C6N15_RS00100	COG1428	Deoxynucleoside kinase
C6N15_RS00105	COG1428	Deoxynucleoside kinase
C6N15_RS00110	COG1335	isochorismatase
C6N15_RS00115	COG0590	tRNA wobble adenosine to inosine editing
C6N15_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C6N15_RS00180	COG1982	Orn Lys Arg decarboxylase major
C6N15_RS00190	COG0470	DNA polymerase III
C6N15_RS00195	COG1774	PSP1 C-terminal conserved region
C6N15_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C6N15_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C6N15_RS00220	COG2002	toxin-antitoxin pair type II binding
C6N15_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N15_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N15_RS00230	COG0084	hydrolase, TatD family'
C6N15_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C6N15_RS00250	COG4466	Protein conserved in bacteria
C6N15_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C6N15_RS00270	COG0251	oxidation-reduction process
C6N15_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C6N15_RS00305	COG2002	toxin-antitoxin pair type II binding
C6N15_RS00310	COG2244	polysaccharide biosynthetic process
C6N15_RS00315	COG3956	TIGRFAM MazG family protein
C6N15_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C6N15_RS00340	COG1098	S1 RNA binding domain
C6N15_RS00355	COG2208	phosphoserine phosphatase activity
C6N15_RS00360	COG0037	tRNA processing
C6N15_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C6N15_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C6N15_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N15_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C6N15_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
C6N15_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N15_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C6N15_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C6N15_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C6N15_RS00420	COG1396	sequence-specific DNA binding
C6N15_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N15_RS00455	COG3880	PFAM UvrB UvrC protein
C6N15_RS00465	COG0542	response to heat
C6N15_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C6N15_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
C6N15_RS00500	COG1045	serine acetyltransferase
C6N15_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N15_RS00520	COG3688	RNA-binding protein containing a PIN domain
C6N15_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6N15_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
C6N15_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C6N15_RS00565	COG2813	Specifically methylates the guanine in position
C6N15_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C6N15_RS00580	COG1358	cellular component organization or biogenesis
C6N15_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
C6N15_RS00710	COG0201	protein transport
C6N15_RS00720	COG0024	Methionine aminopeptidase
C6N15_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C6N15_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C6N15_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS00795	COG0489	protein tyrosine kinase activity
C6N15_RS00805	COG2194	sulfuric ester hydrolase activity
C6N15_RS00810	COG0726	polysaccharide deacetylase
C6N15_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C6N15_RS00895	COG4856	YbbR-like protein
C6N15_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C6N15_RS00915	COG0596	Alpha beta hydrolase
C6N15_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C6N15_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
C6N15_RS00940	COG1506	peptidase
C6N15_RS00940	COG4946	Tricorn protease homolog
C6N15_RS00975	COG2011	ABC-type metal ion transport system permease component
C6N15_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N15_RS00985	COG1464	Belongs to the NlpA lipoprotein family
C6N15_RS00990	COG0604	alcohol dehydrogenase
C6N15_RS01000	COG0277	FAD linked oxidase domain protein
C6N15_RS01005	COG2271	Major facilitator Superfamily
C6N15_RS01015	COG2814	Major facilitator Superfamily
C6N15_RS01030	COG0601	transmembrane transport
C6N15_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N15_RS01040	COG0444	Belongs to the ABC transporter superfamily
C6N15_RS01045	COG4608	Belongs to the ABC transporter superfamily
C6N15_RS01050	COG4166	transmembrane transport
C6N15_RS01060	COG2207	Transcriptional regulator
C6N15_RS01075	COG4166	transmembrane transport
C6N15_RS01080	COG4166	transmembrane transport
C6N15_RS01085	COG0656	L-ascorbic acid biosynthetic process
C6N15_RS01090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N15_RS01105	COG4149	molybdate abc transporter
C6N15_RS01115	COG1910	domain protein
C6N15_RS01125	COG0583	DNA-binding transcription factor activity
C6N15_RS01130	COG0697	spore germination
C6N15_RS01145	COG0204	Acyl-transferase
C6N15_RS01155	COG1609	Transcriptional regulator
C6N15_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS01175	COG0084	hydrolase, TatD family'
C6N15_RS01180	COG5298	Protein conserved in bacteria
C6N15_RS01205	COG0488	(ABC) transporter
C6N15_RS01220	COG0747	negative chemotaxis
C6N15_RS01225	COG0601	transmembrane transport
C6N15_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N15_RS01235	COG0444	Belongs to the ABC transporter superfamily
C6N15_RS01240	COG4608	Belongs to the ABC transporter superfamily
C6N15_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
C6N15_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6N15_RS01290	COG2814	Major facilitator Superfamily
C6N15_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C6N15_RS01310	COG4294	response to UV
C6N15_RS01315	COG0705	Rhomboid family
C6N15_RS01315	COG0457	Tetratricopeptide repeat
C6N15_RS01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C6N15_RS01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6N15_RS01335	COG0864	Transcriptional regulator
C6N15_RS01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
C6N15_RS01345	COG2183	response to ionizing radiation
C6N15_RS01440	COG0802	atpase or kinase
C6N15_RS01445	COG1214	PFAM Peptidase M22, glycoprotease
C6N15_RS01450	COG0456	acetyltransferase
C6N15_RS01460	COG0488	(ABC) transporter
C6N15_RS01475	COG1266	CAAX protease self-immunity
C6N15_RS01495	COG2252	PERMEase
C6N15_RS01505	COG5002	protein histidine kinase activity
C6N15_RS01535	COG2226	methyltransferase
C6N15_RS01575	COG1968	undecaprenyl-diphosphatase activity
C6N15_RS01590	COG2205	protein histidine kinase activity
C6N15_RS01595	COG0745	RESPONSE REGULATOR receiver
C6N15_RS01615	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C6N15_RS01620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C6N15_RS01625	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C6N15_RS01635	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C6N15_RS01650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C6N15_RS01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C6N15_RS01670	COG0151	Belongs to the GarS family
C6N15_RS01695	COG0210	DNA helicase
C6N15_RS01705	COG4851	CamS sex pheromone cAM373 precursor
C6N15_RS01725	COG1335	isochorismatase
C6N15_RS01730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N15_RS01735	COG2011	ABC-type metal ion transport system permease component
C6N15_RS01740	COG1464	Belongs to the NlpA lipoprotein family
C6N15_RS01760	COG1846	Transcriptional regulator
C6N15_RS01785	COG1597	lipid kinase activity
C6N15_RS01790	COG0546	phosphoglycolate phosphatase activity
C6N15_RS01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N15_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS01810	COG2076	Multidrug Resistance protein
C6N15_RS01815	COG2309	aminopeptidase activity
C6N15_RS01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6N15_RS01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C6N15_RS01850	COG4807	Protein conserved in bacteria
C6N15_RS01875	COG1757	Na H antiporter
C6N15_RS01880	COG1473	amidohydrolase
C6N15_RS01895	COG0450	alkyl hydroperoxide reductase
C6N15_RS01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS01940	COG0166	Belongs to the GPI family
C6N15_RS01975	COG5002	protein histidine kinase activity
C6N15_RS01995	COG3541	Predicted nucleotidyltransferase
C6N15_RS02000	COG2814	Major facilitator Superfamily
C6N15_RS02005	COG0723	plastoquinol--plastocyanin reductase activity
C6N15_RS02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N15_RS02015	COG0765	amino acid transport
C6N15_RS02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N15_RS02030	COG0840	transmembrane signaling receptor activity
C6N15_RS02035	COG0840	transmembrane signaling receptor activity
C6N15_RS02040	COG0366	Alpha amylase catalytic
C6N15_RS02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N15_RS02045	COG1263	PTS System
C6N15_RS02045	COG2190	(PTS) system
C6N15_RS02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C6N15_RS02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N15_RS02100	COG1116	anion transmembrane transporter activity
C6N15_RS02105	COG0488	(ABC) transporter
C6N15_RS02150	COG2270	Major facilitator Superfamily
C6N15_RS02165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C6N15_RS02180	COG2310	stress, protein
C6N15_RS02185	COG2310	stress, protein
C6N15_RS02190	COG2310	stress, protein
C6N15_RS02195	COG0861	Integral membrane protein TerC family
C6N15_RS02205	COG3853	Toxic anion resistance protein (TelA)
C6N15_RS02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C6N15_RS02230	COG1295	ribonuclease BN
C6N15_RS02235	COG2217	Heavy metal translocating P-type atpase
C6N15_RS02240	COG0697	spore germination
C6N15_RS02260	COG0586	Pfam SNARE associated Golgi protein
C6N15_RS02275	COG3871	stress protein (general stress protein 26)
C6N15_RS02280	COG0387	Pfam Sodium calcium exchanger
C6N15_RS02290	COG0535	radical SAM domain protein
C6N15_RS02315	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6N15_RS02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C6N15_RS02325	COG0582	viral genome integration into host DNA
C6N15_RS02335	COG1396	sequence-specific DNA binding
C6N15_RS02350	COG1396	sequence-specific DNA binding
C6N15_RS02385	COG1484	DNA-dependent DNA replication
C6N15_RS02615	COG0101	tRNA pseudouridine synthase activity
C6N15_RS02625	COG3829	transcription factor binding
C6N15_RS02635	COG0833	amino acid
C6N15_RS02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6N15_RS02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N15_RS02670	COG1263	PTS System
C6N15_RS02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N15_RS02690	COG0463	Glycosyl transferase, family 2
C6N15_RS02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C6N15_RS02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6N15_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C6N15_RS02745	COG1228	amidohydrolase
C6N15_RS02750	COG1090	epimerase
C6N15_RS02780	COG1988	membrane-bound metal-dependent
C6N15_RS02785	COG1194	a g-specific adenine glycosylase
C6N15_RS02810	COG1132	(ABC) transporter
C6N15_RS02815	COG4129	membrane
C6N15_RS02820	COG0069	glutamate synthase activity
C6N15_RS02820	COG0067	glutamate synthase
C6N15_RS02820	COG0070	glutamate synthase
C6N15_RS02830	COG4555	ABC transporter
C6N15_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C6N15_RS02855	COG0735	belongs to the Fur family
C6N15_RS02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C6N15_RS02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C6N15_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C6N15_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C6N15_RS03005	COG2766	serine protein kinase
C6N15_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N15_RS03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
C6N15_RS03040	COG2268	Band 7 protein
C6N15_RS03050	COG3290	protein histidine kinase activity
C6N15_RS03055	COG4565	transcriptional regulatory protein
C6N15_RS03060	COG2851	Citrate transporter
C6N15_RS03080	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6N15_RS03085	COG3842	ATPase activity
C6N15_RS03090	COG1175	transmembrane transport
C6N15_RS03095	COG0395	ABC-type sugar transport system, permease component
C6N15_RS03105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C6N15_RS03110	COG0745	RESPONSE REGULATOR receiver
C6N15_RS03115	COG5002	protein histidine kinase activity
C6N15_RS03125	COG4990	cell redox homeostasis
C6N15_RS03135	COG3290	protein histidine kinase activity
C6N15_RS03140	COG4565	transcriptional regulatory protein
C6N15_RS03145	COG3493	citrate carrier protein
C6N15_RS03150	COG0281	malic enzyme
C6N15_RS03165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS03175	COG5002	protein histidine kinase activity
C6N15_RS03180	COG0745	RESPONSE REGULATOR receiver
C6N15_RS03185	COG0456	acetyltransferase
C6N15_RS03185	COG0454	-acetyltransferase
C6N15_RS03190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C6N15_RS03195	COG3383	formate dehydrogenase (NAD+) activity
C6N15_RS03200	COG2427	Protein of unknown function (DUF1641)
C6N15_RS03215	COG0531	amino acid
C6N15_RS03220	COG0640	Transcriptional regulator
C6N15_RS03225	COG2217	Heavy metal translocating P-type atpase
C6N15_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C6N15_RS03245	COG3227	Zinc metalloprotease (Elastase)
C6N15_RS03265	COG2720	vancomycin resistance protein
C6N15_RS03270	COG1316	TRANSCRIPTIONal
C6N15_RS03275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS03280	COG0346	lactoylglutathione lyase activity
C6N15_RS03285	COG1253	flavin adenine dinucleotide binding
C6N15_RS03290	COG1027	Aspartate ammonia-lyase
C6N15_RS03295	COG1620	l-lactate permease
C6N15_RS03310	COG3104	oligopeptide transport
C6N15_RS03315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS03320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS03325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS03335	COG2226	methyltransferase
C6N15_RS03340	COG0156	8-amino-7-oxononanoate synthase activity
C6N15_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6N15_RS03355	COG4548	von Willebrand factor, type A
C6N15_RS03360	COG0714	Associated with various cellular activities
C6N15_RS03365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N15_RS03385	COG0531	amino acid
C6N15_RS03390	COG2188	Transcriptional regulator
C6N15_RS03395	COG1263	PTS System
C6N15_RS03395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N15_RS03400	COG0366	Alpha amylase catalytic
C6N15_RS03415	COG0697	spore germination
C6N15_RS03425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N15_RS03430	COG1115	amino acid carrier protein
C6N15_RS03435	COG1126	abc transporter atp-binding protein
C6N15_RS03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N15_RS03445	COG0765	amino acid transport
C6N15_RS03450	COG0765	amino acid transport
C6N15_RS03455	COG0833	amino acid
C6N15_RS03480	COG2378	regulation of single-species biofilm formation
C6N15_RS03485	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C6N15_RS03490	COG5002	protein histidine kinase activity
C6N15_RS03505	COG0659	secondary active sulfate transmembrane transporter activity
C6N15_RS03520	COG0747	negative chemotaxis
C6N15_RS03530	COG0601	transmembrane transport
C6N15_RS03535	COG4608	Belongs to the ABC transporter superfamily
C6N15_RS03545	COG2271	Major facilitator Superfamily
C6N15_RS03550	COG1846	Transcriptional regulator
C6N15_RS03560	COG1609	Transcriptional regulator
C6N15_RS03565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N15_RS03580	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N15_RS03585	COG1879	ABC-type sugar transport system periplasmic component
C6N15_RS03610	COG1063	alcohol dehydrogenase
C6N15_RS03625	COG3568	Endonuclease Exonuclease Phosphatase
C6N15_RS03650	COG1968	undecaprenyl-diphosphatase activity
C6N15_RS03655	COG0840	transmembrane signaling receptor activity
C6N15_RS03660	COG3584	3D domain protein
C6N15_RS03660	COG1388	LysM domain
C6N15_RS03665	COG1476	TRANSCRIPTIONal
C6N15_RS03680	COG3104	oligopeptide transport
C6N15_RS03685	COG1114	Component of the transport system for branched-chain amino acids
C6N15_RS03700	COG1113	amino acid transport
C6N15_RS03705	COG2252	PERMEase
C6N15_RS03730	COG0475	glutathione-regulated potassium exporter activity
C6N15_RS03730	COG0569	domain protein
C6N15_RS03745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C6N15_RS03750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C6N15_RS03755	COG0833	amino acid
C6N15_RS03760	COG4990	cell redox homeostasis
C6N15_RS03775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N15_RS03780	COG0697	spore germination
C6N15_RS03785	COG0531	amino acid
C6N15_RS03795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6N15_RS03800	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6N15_RS03805	COG1918	ferrous iron import across plasma membrane
C6N15_RS03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C6N15_RS03810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N15_RS03815	COG0573	inorganic phosphate transmembrane transporter activity
C6N15_RS03820	COG0581	inorganic phosphate transmembrane transporter activity
C6N15_RS03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N15_RS03950	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C6N15_RS03970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6N15_RS03975	COG1116	anion transmembrane transporter activity
C6N15_RS03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N15_RS03985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N15_RS03990	COG0352	thiamine-phosphate diphosphorylase activity
C6N15_RS03995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N15_RS04000	COG2104	thiamine diphosphate biosynthetic process
C6N15_RS04010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6N15_RS04015	COG0351	phosphomethylpyrimidine kinase
C6N15_RS04055	COG2205	protein histidine kinase activity
C6N15_RS04060	COG2814	Major facilitator Superfamily
C6N15_RS04065	COG1846	Transcriptional regulator
C6N15_RS04080	COG2252	PERMEase
C6N15_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS04100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C6N15_RS04105	COG1621	beta-fructofuranosidase activity
C6N15_RS04110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N15_RS04110	COG1263	PTS System
C6N15_RS04115	COG1609	Transcriptional regulator
C6N15_RS04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6N15_RS04130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C6N15_RS04165	COG0778	Nitroreductase
C6N15_RS04170	COG2719	SpoVR family
C6N15_RS04195	COG0446	pyridine nucleotide-disulphide oxidoreductase
C6N15_RS04200	COG1937	Protein conserved in bacteria
C6N15_RS04205	COG0425	Belongs to the sulfur carrier protein TusA family
C6N15_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N15_RS04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N15_RS04215	COG0425	Belongs to the sulfur carrier protein TusA family
C6N15_RS04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N15_RS04230	COG2210	Belongs to the sulfur carrier protein TusA family
C6N15_RS04235	COG0730	response to heat
C6N15_RS04245	COG1316	TRANSCRIPTIONal
C6N15_RS04250	COG0604	alcohol dehydrogenase
C6N15_RS04255	COG1283	sodium-dependent phosphate transmembrane transporter activity
C6N15_RS04270	COG3711	transcriptional antiterminator
C6N15_RS04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N15_RS04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N15_RS04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N15_RS04300	COG1388	LysM domain
C6N15_RS04300	COG3584	3D domain protein
C6N15_RS04305	COG0577	efflux transmembrane transporter activity
C6N15_RS04310	COG1136	(ABC) transporter
C6N15_RS04320	COG5522	Integral membrane protein (intg_mem_TP0381)
C6N15_RS04335	COG1114	Component of the transport system for branched-chain amino acids
C6N15_RS04340	COG3546	catalase activity
C6N15_RS04375	COG0586	Pfam SNARE associated Golgi protein
C6N15_RS04410	COG0531	amino acid
C6N15_RS04415	COG0475	glutathione-regulated potassium exporter activity
C6N15_RS04425	COG1737	Transcriptional regulator
C6N15_RS04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N15_RS04435	COG1263	PTS System
C6N15_RS04445	COG2259	Doxx family
C6N15_RS04460	COG0697	spore germination
C6N15_RS04465	COG1522	sequence-specific DNA binding
C6N15_RS04480	COG2076	Multidrug Resistance protein
C6N15_RS04485	COG1309	transcriptional regulator
C6N15_RS04490	COG2814	Major facilitator Superfamily
C6N15_RS04495	COG1733	regulation of RNA biosynthetic process
C6N15_RS04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N15_RS04510	COG4533	DNA binding
C6N15_RS04515	COG2211	Major facilitator Superfamily
C6N15_RS04525	COG0693	protein deglycase activity
C6N15_RS04530	COG0693	protein deglycase activity
C6N15_RS04530	COG0753	catalase activity
C6N15_RS04540	COG0531	amino acid
C6N15_RS04545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C6N15_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS04560	COG1132	(ABC) transporter
C6N15_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N15_RS04575	COG0765	amino acid transport
C6N15_RS04580	COG1126	abc transporter atp-binding protein
C6N15_RS04595	COG0189	ligase activity
C6N15_RS04625	COG0028	Belongs to the TPP enzyme family
C6N15_RS04630	COG3527	Alpha-acetolactate decarboxylase
C6N15_RS04645	COG0561	phosphatase activity
C6N15_RS04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6N15_RS04675	COG0659	secondary active sulfate transmembrane transporter activity
C6N15_RS04695	COG0653	protein targeting
C6N15_RS04700	COG2244	polysaccharide biosynthetic process
C6N15_RS04710	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS04715	COG4196	transglutaminase domain protein
C6N15_RS04730	COG1696	Membrane protein involved in D-alanine export
C6N15_RS04745	COG1024	Enoyl-CoA hydratase
C6N15_RS04765	COG1363	Peptidase, m42
C6N15_RS04785	COG3938	Belongs to the proline racemase family
C6N15_RS04825	COG0601	transmembrane transport
C6N15_RS04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N15_RS04840	COG4608	Belongs to the ABC transporter superfamily
C6N15_RS04845	COG0322	excinuclease ABC activity
C6N15_RS04875	COG0477	Major facilitator Superfamily
C6N15_RS04880	COG3290	protein histidine kinase activity
C6N15_RS04885	COG4565	transcriptional regulatory protein
C6N15_RS04890	COG3181	Tripartite tricarboxylate transporter family receptor
C6N15_RS04920	COG0789	Transcriptional regulator
C6N15_RS04920	COG4978	Transcriptional regulator
C6N15_RS04935	COG0305	Participates in initiation and elongation during chromosome replication
C6N15_RS04975	COG0477	Major facilitator Superfamily
C6N15_RS05020	COG3320	Male sterility
C6N15_RS05020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N15_RS05025	COG1309	transcriptional regulator
C6N15_RS05045	COG1183	phosphatidylcholine synthase activity
C6N15_RS05065	COG2376	Dihydroxyacetone kinase
C6N15_RS05075	COG2376	Dihydroxyacetone kinase
C6N15_RS05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N15_RS05085	COG1959	2 iron, 2 sulfur cluster binding
C6N15_RS05115	COG3437	response regulator, receiver
C6N15_RS05115	COG2770	Histidine kinase
C6N15_RS05165	COG3237	CsbD-like
C6N15_RS05190	COG1191	sigma factor activity
C6N15_RS05200	COG2208	phosphoserine phosphatase activity
C6N15_RS05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6N15_RS05210	COG2205	protein histidine kinase activity
C6N15_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N15_RS05210	COG2198	Histidine kinase
C6N15_RS05210	COG0784	Response regulator, receiver
C6N15_RS05265	COG0420	3'-5' exonuclease activity
C6N15_RS05270	COG4717	serine-type aminopeptidase activity
C6N15_RS05290	COG1309	transcriptional regulator
C6N15_RS05295	COG2814	Major facilitator Superfamily
C6N15_RS05300	COG0346	lactoylglutathione lyase activity
C6N15_RS05310	COG0346	lactoylglutathione lyase activity
C6N15_RS05315	COG0457	Tetratricopeptide repeat
C6N15_RS05320	COG2267	carboxylic ester hydrolase activity
C6N15_RS05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C6N15_RS05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C6N15_RS05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C6N15_RS05395	COG0477	Major facilitator Superfamily
C6N15_RS05400	COG0477	Major facilitator Superfamily
C6N15_RS05410	COG3973	AAA domain
C6N15_RS05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N15_RS05435	COG4980	gas vesicle protein
C6N15_RS05440	COG0537	adenosine 5'-monophosphoramidase activity
C6N15_RS05445	COG1131	(ABC) transporter
C6N15_RS05450	COG4473	ABC transporter
C6N15_RS05465	COG1309	transcriptional regulator
C6N15_RS05475	COG3402	PFAM membrane-flanked domain
C6N15_RS05525	COG3402	PFAM membrane-flanked domain
C6N15_RS05530	COG3428	Bacterial PH domain
C6N15_RS05535	COG2329	Antibiotic biosynthesis monooxygenase
C6N15_RS05540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N15_RS05545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C6N15_RS05550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C6N15_RS05555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C6N15_RS05590	COG1309	transcriptional regulator
C6N15_RS05595	COG1511	domain protein
C6N15_RS05620	COG1609	Transcriptional regulator
C6N15_RS05630	COG1234	tRNA 3'-trailer cleavage
C6N15_RS05635	COG0095	Lipoate-protein ligase
C6N15_RS05645	COG0318	PFAM AMP-dependent synthetase and ligase
C6N15_RS05675	COG3209	COG3209 Rhs family protein
C6N15_RS05715	COG1078	dGTPase activity
C6N15_RS05725	COG1595	DNA-templated transcription, initiation
C6N15_RS05730	COG3708	Transcriptional regulator
C6N15_RS05730	COG2207	Transcriptional regulator
C6N15_RS05745	COG2205	protein histidine kinase activity
C6N15_RS05750	COG0745	RESPONSE REGULATOR receiver
C6N15_RS05775	COG0501	Belongs to the peptidase M48B family
C6N15_RS05780	COG0840	transmembrane signaling receptor activity
C6N15_RS05785	COG0697	spore germination
C6N15_RS05805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C6N15_RS05810	COG2224	Isocitrate lyase
C6N15_RS05835	COG4903	ComK protein
C6N15_RS05840	COG0398	Pfam SNARE associated Golgi protein
C6N15_RS05850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C6N15_RS05855	COG1074	ATP-dependent DNA helicase activity
C6N15_RS05900	COG0179	Fumarylacetoacetate (FAA) hydrolase
C6N15_RS05925	COG0367	asparagine synthase
C6N15_RS05930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C6N15_RS05935	COG0753	catalase activity
C6N15_RS05940	COG0004	ammonium transporteR
C6N15_RS05960	COG2996	Protein conserved in bacteria
C6N15_RS05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N15_RS05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS05995	COG0561	phosphatase activity
C6N15_RS06005	COG0542	response to heat
C6N15_RS06015	COG2267	carboxylic ester hydrolase activity
C6N15_RS06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N15_RS06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C6N15_RS06040	COG5504	Zn-dependent protease
C6N15_RS06050	COG0180	Tryptophanyl-tRNA synthetase
C6N15_RS06060	COG4166	transmembrane transport
C6N15_RS06065	COG0601	transmembrane transport
C6N15_RS06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N15_RS06075	COG0444	Belongs to the ABC transporter superfamily
C6N15_RS06080	COG4608	Belongs to the ABC transporter superfamily
C6N15_RS06085	COG0534	Mate efflux family protein
C6N15_RS06090	COG4166	transmembrane transport
C6N15_RS06105	COG0861	Integral membrane protein TerC family
C6N15_RS06110	COG4862	establishment of competence for transformation
C6N15_RS06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N15_RS06125	COG1164	Oligoendopeptidase f
C6N15_RS06135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C6N15_RS06140	COG2346	COG2346, Truncated hemoglobins
C6N15_RS06145	COG4116	CYTH
C6N15_RS06155	COG2357	RelA SpoT domain protein
C6N15_RS06165	COG0564	pseudouridine synthase activity
C6N15_RS06185	COG1216	Glycosyl transferase, family 2
C6N15_RS06185	COG0463	Glycosyl transferase, family 2
C6N15_RS06205	COG0457	Tetratricopeptide repeat
C6N15_RS06205	COG0463	Glycosyl transferase, family 2
C6N15_RS06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C6N15_RS06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
C6N15_RS06285	COG2153	protein acetylation
C6N15_RS06295	COG2382	esterase
C6N15_RS06310	COG5492	domain, Protein
C6N15_RS06315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N15_RS06325	COG0512	Glutamine amidotransferase of anthranilate synthase
C6N15_RS06325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C6N15_RS06360	COG1620	l-lactate permease
C6N15_RS06365	COG5634	Uncharacterized conserved protein (DUF2278)
C6N15_RS06420	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N15_RS06430	COG1476	TRANSCRIPTIONal
C6N15_RS06490	COG2226	methyltransferase
C6N15_RS06500	COG1686	Belongs to the peptidase S11 family
C6N15_RS06505	COG0681	Belongs to the peptidase S26 family
C6N15_RS06540	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS06545	COG3842	ATPase activity
C6N15_RS06550	COG1176	ABC-type spermidine putrescine transport system, permease component I
C6N15_RS06555	COG1177	transmembrane transport
C6N15_RS06560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C6N15_RS06570	COG2409	Drug exporters of the RND superfamily
C6N15_RS06580	COG0564	pseudouridine synthase activity
C6N15_RS06590	COG2340	Cysteine-rich secretory protein family
C6N15_RS06595	COG0247	lactate metabolic process
C6N15_RS06600	COG0277	FAD linked oxidase domain protein
C6N15_RS06605	COG3835	regulator
C6N15_RS06615	COG0745	RESPONSE REGULATOR receiver
C6N15_RS06620	COG5002	protein histidine kinase activity
C6N15_RS06625	COG2186	Transcriptional regulator
C6N15_RS06645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C6N15_RS06660	COG2116	formate transmembrane transporter activity
C6N15_RS06665	COG0861	Integral membrane protein TerC family
C6N15_RS06670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N15_RS06680	COG2030	dehydratase
C6N15_RS06700	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS06705	COG3243	poly(R)-hydroxyalkanoic acid synthase
C6N15_RS06710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N15_RS06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N15_RS06730	COG1840	ABC-type Fe3 transport system, periplasmic component
C6N15_RS06760	COG1349	DNA-binding transcription factor activity
C6N15_RS06780	COG2861	carbohydrate metabolic process
C6N15_RS06790	COG3852	Histidine kinase
C6N15_RS06795	COG1846	Transcriptional regulator
C6N15_RS06805	COG2318	DinB family
C6N15_RS06810	COG5002	protein histidine kinase activity
C6N15_RS06820	COG0720	synthase
C6N15_RS06835	COG4873	Protein conserved in bacteria
C6N15_RS06865	COG1780	Probably involved in ribonucleotide reductase function
C6N15_RS06885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C6N15_RS06890	COG1725	Transcriptional regulator
C6N15_RS06895	COG1131	(ABC) transporter
C6N15_RS06905	COG1131	(ABC) transporter
C6N15_RS06910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C6N15_RS06925	COG1522	sequence-specific DNA binding
C6N15_RS06935	COG1335	isochorismatase
C6N15_RS06945	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6N15_RS06950	COG2070	2-Nitropropane dioxygenase
C6N15_RS06955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C6N15_RS06965	COG1696	Membrane protein involved in D-alanine export
C6N15_RS06990	COG0716	FMN binding
C6N15_RS07005	COG3173	Aminoglycoside phosphotransferase
C6N15_RS07025	COG0534	Mate efflux family protein
C6N15_RS07030	COG1968	undecaprenyl-diphosphatase activity
C6N15_RS07045	COG1846	Transcriptional regulator
C6N15_RS07055	COG1301	dicarboxylic acid transport
C6N15_RS07060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C6N15_RS07065	COG4709	membrane
C6N15_RS07070	COG3874	Sporulation protein YtfJ
C6N15_RS07095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N15_RS07100	COG0028	Belongs to the TPP enzyme family
C6N15_RS07105	COG0440	acetolactate synthase activity
C6N15_RS07110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C6N15_RS07120	COG0473	3-isopropylmalate dehydrogenase activity
C6N15_RS07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C6N15_RS07180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C6N15_RS07195	COG1183	phosphatidylcholine synthase activity
C6N15_RS07200	COG1368	sulfuric ester hydrolase activity
C6N15_RS07210	COG0019	diaminopimelate decarboxylase activity
C6N15_RS07230	COG0529	Catalyzes the synthesis of activated sulfate
C6N15_RS07235	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N15_RS07255	COG1648	precorrin-2 dehydrogenase activity
C6N15_RS07260	COG0733	neurotransmitter:sodium symporter activity
C6N15_RS07280	COG1757	Na H antiporter
C6N15_RS07295	COG4758	membrane
C6N15_RS07300	COG4585	Histidine kinase
C6N15_RS07305	COG2197	response regulator
C6N15_RS07315	COG1114	Component of the transport system for branched-chain amino acids
C6N15_RS07325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C6N15_RS07350	COG1017	nitric oxide dioxygenase activity
C6N15_RS07350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C6N15_RS07365	COG0730	response to heat
C6N15_RS07370	COG0306	phosphate transporter
C6N15_RS07375	COG1392	Phosphate transport regulator
C6N15_RS07380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N15_RS07395	COG3852	Histidine kinase
C6N15_RS07400	COG1801	Protein of unknown function DUF72
C6N15_RS07410	COG0582	viral genome integration into host DNA
C6N15_RS07415	COG5002	protein histidine kinase activity
C6N15_RS07435	COG0392	lysyltransferase activity
C6N15_RS07435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C6N15_RS07450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N15_RS07455	COG1686	Belongs to the peptidase S11 family
C6N15_RS07460	COG2715	membrane protein required for spore maturation
C6N15_RS07465	COG0700	Nucleoside recognition
C6N15_RS07470	COG1187	pseudouridine synthase activity
C6N15_RS07480	COG1333	cytochrome c biogenesis protein
C6N15_RS07485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6N15_RS07490	COG0745	RESPONSE REGULATOR receiver
C6N15_RS07495	COG5002	protein histidine kinase activity
C6N15_RS07500	COG2096	Adenosyltransferase
C6N15_RS07515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C6N15_RS07520	COG1141	Ferredoxin
C6N15_RS07525	COG4955	Helix-turn-helix domain
C6N15_RS07530	COG0514	ATP-dependent DNA helicase (RecQ)
C6N15_RS07535	COG1266	CAAX protease self-immunity
C6N15_RS07555	COG4862	establishment of competence for transformation
C6N15_RS07560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C6N15_RS07580	COG0492	ferredoxin-NADP+ reductase activity
C6N15_RS07655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C6N15_RS07670	COG0142	geranyltranstransferase activity
C6N15_RS07680	COG0142	geranyltranstransferase activity
C6N15_RS07700	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C6N15_RS07705	COG0457	Tetratricopeptide repeat
C6N15_RS07725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C6N15_RS07735	COG4347	Protein of unknown function (DUF1405)
C6N15_RS07750	COG2738	Putative neutral zinc metallopeptidase
C6N15_RS07760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS07765	COG1694	Mazg nucleotide pyrophosphohydrolase
C6N15_RS07780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6N15_RS07785	COG0438	transferase activity, transferring glycosyl groups
C6N15_RS07820	COG1199	ATP-dependent helicase activity
C6N15_RS07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C6N15_RS07840	COG3935	DnaD domain protein
C6N15_RS07845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C6N15_RS07855	COG4499	WXG100 protein secretion system (Wss), protein YukC
C6N15_RS07855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N15_RS07915	COG0116	Belongs to the methyltransferase superfamily
C6N15_RS07925	COG1199	ATP-dependent helicase activity
C6N15_RS07930	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C6N15_RS07940	COG3173	Aminoglycoside phosphotransferase
C6N15_RS07945	COG0024	Methionine aminopeptidase
C6N15_RS07955	COG2233	PERMEase
C6N15_RS07960	COG2311	Membrane
C6N15_RS07965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C6N15_RS07975	COG0456	acetyltransferase
C6N15_RS08025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N15_RS08050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C6N15_RS08065	COG1215	transferase activity, transferring glycosyl groups
C6N15_RS08070	COG0438	transferase activity, transferring glycosyl groups
C6N15_RS08085	COG0454	-acetyltransferase
C6N15_RS08105	COG0328	RNA-DNA hybrid ribonuclease activity
C6N15_RS08145	COG1280	lysine exporter protein (LysE YggA)
C6N15_RS08160	COG3162	membrane
C6N15_RS08165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N15_RS08170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6N15_RS08180	COG0475	glutathione-regulated potassium exporter activity
C6N15_RS08185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C6N15_RS08190	COG4978	Transcriptional regulator
C6N15_RS08190	COG0789	Transcriptional regulator
C6N15_RS08200	COG2323	membrane
C6N15_RS08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C6N15_RS08260	COG1923	regulation of RNA biosynthetic process
C6N15_RS08270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6N15_RS08275	COG1360	Flagellar Motor Protein
C6N15_RS08280	COG2201	protein-glutamate methylesterase activity
C6N15_RS08285	COG2198	Histidine kinase
C6N15_RS08285	COG0643	Histidine kinase
C6N15_RS08290	COG0643	Histidine kinase
C6N15_RS08290	COG2198	Histidine kinase
C6N15_RS08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6N15_RS08295	COG1776	CheC inhibitor of MCP methylation
C6N15_RS08310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C6N15_RS08330	COG1256	bacterial-type flagellum assembly
C6N15_RS08355	COG1815	bacterial-type flagellum-dependent cell motility
C6N15_RS08360	COG1558	bacterial-type flagellum-dependent cell motility
C6N15_RS08375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6N15_RS08385	COG1157	protein secretion by the type III secretion system
C6N15_RS08425	COG0784	Response regulator, receiver
C6N15_RS08425	COG0835	chemotaxis
C6N15_RS08435	COG0463	Glycosyl transferase, family 2
C6N15_RS08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C6N15_RS08475	COG0741	lytic transglycosylase activity
C6N15_RS08490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C6N15_RS08490	COG1776	CheC inhibitor of MCP methylation
C6N15_RS08500	COG1338	Plays a role in the flagellum-specific transport system
C6N15_RS08505	COG1987	bacterial-type flagellum assembly
C6N15_RS08515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6N15_RS08520	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C6N15_RS08525	COG1419	protein localization to endoplasmic reticulum
C6N15_RS08530	COG4786	Flagellar basal body rod
C6N15_RS08535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6N15_RS08560	COG1309	transcriptional regulator
C6N15_RS08580	COG2329	Antibiotic biosynthesis monooxygenase
C6N15_RS08605	COG0583	DNA-binding transcription factor activity
C6N15_RS08610	COG3842	ATPase activity
C6N15_RS08615	COG0725	ABC transporter, periplasmic molybdate-binding protein
C6N15_RS08625	COG1234	tRNA 3'-trailer cleavage
C6N15_RS08650	COG1686	Belongs to the peptidase S11 family
C6N15_RS08660	COG0406	alpha-ribazole phosphatase activity
C6N15_RS08690	COG0367	asparagine synthase
C6N15_RS08720	COG1802	Transcriptional regulator
C6N15_RS08725	COG0697	spore germination
C6N15_RS08730	COG0523	cobalamin synthesis protein
C6N15_RS08735	COG0701	Predicted permease
C6N15_RS08745	COG0438	transferase activity, transferring glycosyl groups
C6N15_RS08745	COG1216	Glycosyl transferase, family 2
C6N15_RS08750	COG1757	Na H antiporter
C6N15_RS08755	COG0114	fumarate hydratase activity
C6N15_RS08780	COG3340	Belongs to the peptidase S51 family
C6N15_RS08800	COG0785	Cytochrome C biogenesis protein
C6N15_RS08830	COG2733	membrane
C6N15_RS08865	COG1131	(ABC) transporter
C6N15_RS08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N15_RS08885	COG0528	UMP kinase activity
C6N15_RS08895	COG1027	Aspartate ammonia-lyase
C6N15_RS08900	COG0281	malic enzyme
C6N15_RS08905	COG4191	Histidine kinase
C6N15_RS08910	COG0784	Response regulator, receiver
C6N15_RS08915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C6N15_RS08970	COG1051	belongs to the nudix hydrolase family
C6N15_RS08975	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS08985	COG2814	Major facilitator Superfamily
C6N15_RS09000	COG1966	Carbon starvation protein
C6N15_RS09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N15_RS09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C6N15_RS09035	COG2223	nitrite transmembrane transporter activity
C6N15_RS09040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N15_RS09055	COG2244	polysaccharide biosynthetic process
C6N15_RS09060	COG0733	neurotransmitter:sodium symporter activity
C6N15_RS09070	COG5566	PFAM Mor transcription activator
C6N15_RS09075	COG2323	membrane
C6N15_RS09090	COG2084	Dehydrogenase
C6N15_RS09105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6N15_RS09115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N15_RS09120	COG0028	Belongs to the TPP enzyme family
C6N15_RS09125	COG0440	acetolactate synthase activity
C6N15_RS09130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C6N15_RS09140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C6N15_RS09165	COG2814	Major facilitator Superfamily
C6N15_RS09170	COG3384	dioxygenase
C6N15_RS09180	COG3279	Response regulator of the LytR AlgR family
C6N15_RS09185	COG0427	acetyl-CoA hydrolase
C6N15_RS09205	COG1073	alpha beta
C6N15_RS09235	COG0535	radical SAM domain protein
C6N15_RS09240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS09260	COG1914	H( )-stimulated, divalent metal cation uptake system
C6N15_RS09275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6N15_RS09305	COG2390	Transcriptional regulator
C6N15_RS09315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS09320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C6N15_RS09335	COG4224	UPF0291 protein
C6N15_RS09355	COG0006	proline dipeptidase activity
C6N15_RS09360	COG2132	Multicopper oxidase
C6N15_RS09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6N15_RS09390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N15_RS09405	COG2372	response to copper ion
C6N15_RS09405	COG1276	copper resistance
C6N15_RS09410	COG4549	nuclear export factor GLE1
C6N15_RS09420	COG0697	spore germination
C6N15_RS09425	COG0583	DNA-binding transcription factor activity
C6N15_RS09430	COG1959	2 iron, 2 sulfur cluster binding
C6N15_RS09435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C6N15_RS09440	COG0778	Nitroreductase
C6N15_RS09450	COG0628	permease
C6N15_RS09460	COG1231	oxidoreductase activity
C6N15_RS09465	COG0523	cobalamin synthesis protein
C6N15_RS09480	COG0318	PFAM AMP-dependent synthetase and ligase
C6N15_RS09485	COG2030	dehydratase
C6N15_RS09490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N15_RS09500	COG0411	ABC transporter
C6N15_RS09520	COG0583	DNA-binding transcription factor activity
C6N15_RS09540	COG1846	Transcriptional regulator
C6N15_RS09550	COG1271	oxidase subunit
C6N15_RS09555	COG1294	oxidase, subunit
C6N15_RS09560	COG4988	ABC transporter
C6N15_RS09565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C6N15_RS09585	COG1686	Belongs to the peptidase S11 family
C6N15_RS09600	COG1388	LysM domain
C6N15_RS09600	COG0791	NLP P60 protein
C6N15_RS09615	COG0745	RESPONSE REGULATOR receiver
C6N15_RS09620	COG5002	protein histidine kinase activity
C6N15_RS09630	COG0300	oxidoreductase activity
C6N15_RS09665	COG0460	homoserine dehydrogenase
C6N15_RS09690	COG1316	TRANSCRIPTIONal
C6N15_RS09700	COG0745	RESPONSE REGULATOR receiver
C6N15_RS09705	COG5002	protein histidine kinase activity
C6N15_RS09720	COG1285	pathogenesis
C6N15_RS09725	COG1247	-acetyltransferase
C6N15_RS09745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N15_RS09755	COG1082	Xylose isomerase domain protein TIM barrel
C6N15_RS09770	COG1279	arginine transmembrane transporter activity
C6N15_RS09820	COG2002	toxin-antitoxin pair type II binding
C6N15_RS09825	COG1404	Belongs to the peptidase S8 family
C6N15_RS09830	COG0640	Transcriptional regulator
C6N15_RS09835	COG0667	Aldo Keto reductase
C6N15_RS09840	COG2814	Major facilitator Superfamily
C6N15_RS09865	COG0840	transmembrane signaling receptor activity
C6N15_RS09880	COG3949	Membrane
C6N15_RS09885	COG0783	Belongs to the Dps family
C6N15_RS09900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N15_RS09910	COG1231	oxidoreductase activity
C6N15_RS09920	COG4989	oxidoreductase activity
C6N15_RS09925	COG0523	cobalamin synthesis protein
C6N15_RS09930	COG0456	acetyltransferase
C6N15_RS09985	COG0803	Belongs to the bacterial solute-binding protein 9 family
C6N15_RS09985	COG3443	Belongs to the bacterial solute-binding protein 9 family
C6N15_RS09995	COG0702	epimerase
C6N15_RS10005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N15_RS10015	COG4166	transmembrane transport
C6N15_RS10030	COG0406	alpha-ribazole phosphatase activity
C6N15_RS10040	COG5337	Spore coat protein CotH
C6N15_RS10045	COG1051	belongs to the nudix hydrolase family
C6N15_RS10050	COG0586	Pfam SNARE associated Golgi protein
C6N15_RS10055	COG2244	polysaccharide biosynthetic process
C6N15_RS10065	COG0701	Predicted permease
C6N15_RS10070	COG3689	TIGRFAM TIGR03943 family protein
C6N15_RS10075	COG1607	acyl-coa hydrolase
C6N15_RS10085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N15_RS10100	COG0702	epimerase
C6N15_RS10105	COG2839	Protein conserved in bacteria
C6N15_RS10110	COG1253	flavin adenine dinucleotide binding
C6N15_RS10125	COG1114	Component of the transport system for branched-chain amino acids
C6N15_RS10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N15_RS10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS10160	COG1876	peptidase activity
C6N15_RS10170	COG0154	amidase activity
C6N15_RS10175	COG2211	Major facilitator Superfamily
C6N15_RS10195	COG0561	phosphatase activity
C6N15_RS10205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C6N15_RS10210	COG4106	trans-aconitate 2-methyltransferase activity
C6N15_RS10225	COG1819	glycosyl
C6N15_RS10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS10260	COG0456	acetyltransferase
C6N15_RS10310	COG3874	Sporulation protein YtfJ
C6N15_RS10335	COG2226	methyltransferase
C6N15_RS10360	COG0346	lactoylglutathione lyase activity
C6N15_RS10370	COG0604	alcohol dehydrogenase
C6N15_RS10375	COG1595	DNA-templated transcription, initiation
C6N15_RS10400	COG0386	Belongs to the glutathione peroxidase family
C6N15_RS10405	COG1305	Transglutaminase-like
C6N15_RS10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C6N15_RS10415	COG0714	Associated with various cellular activities
C6N15_RS10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C6N15_RS10435	COG1140	nitrate reductase beta subunit
C6N15_RS10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C6N15_RS10445	COG2181	nitrate reductase activity
C6N15_RS10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N15_RS10470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C6N15_RS10475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6N15_RS10480	COG0303	'Molybdopterin
C6N15_RS10485	COG0314	molybdopterin synthase activity
C6N15_RS10495	COG2223	nitrite transmembrane transporter activity
C6N15_RS10510	COG1648	precorrin-2 dehydrogenase activity
C6N15_RS10520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C6N15_RS10520	COG1587	Uroporphyrinogen-III synthase
C6N15_RS10525	COG2146	nitrite reductase [NAD(P)H] activity
C6N15_RS10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C6N15_RS10535	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
C6N15_RS10570	COG2359	stage V sporulation protein S
C6N15_RS10585	COG5632	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS10600	COG1418	mRNA catabolic process
C6N15_RS10620	COG0629	single-stranded DNA binding
C6N15_RS10635	COG1413	lyase activity
C6N15_RS10650	COG2136	Putative SAM-dependent methyltransferase
C6N15_RS10650	COG2521	methyltransferase
C6N15_RS10655	COG0018	arginyl-trna synthetase
C6N15_RS10680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C6N15_RS10700	COG0017	Asparaginyl-tRNA synthetase
C6N15_RS10720	COG1674	ftsk spoiiie
C6N15_RS10790	COG1929	Belongs to the glycerate kinase type-1 family
C6N15_RS10795	COG0471	metal ion transport
C6N15_RS10800	COG0745	RESPONSE REGULATOR receiver
C6N15_RS10805	COG3850	Histidine kinase
C6N15_RS10805	COG5002	protein histidine kinase activity
C6N15_RS10820	COG0733	neurotransmitter:sodium symporter activity
C6N15_RS10845	COG2610	gluconate transmembrane transporter activity
C6N15_RS10850	COG1454	alcohol dehydrogenase
C6N15_RS10855	COG1794	racemase activity, acting on amino acids and derivatives
C6N15_RS10865	COG0456	acetyltransferase
C6N15_RS10880	COG1131	(ABC) transporter
C6N15_RS10895	COG0546	phosphoglycolate phosphatase activity
C6N15_RS10915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N15_RS10930	COG0768	penicillin binding
C6N15_RS10935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C6N15_RS10940	COG0204	Acyl-transferase
C6N15_RS10945	COG1272	protein, Hemolysin III
C6N15_RS10955	COG0805	protein transport
C6N15_RS10965	COG1307	EDD domain protein, DegV family
C6N15_RS10970	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C6N15_RS10975	COG1999	signal sequence binding
C6N15_RS10980	COG0071	Belongs to the small heat shock protein (HSP20) family
C6N15_RS10985	COG0367	asparagine synthase
C6N15_RS11000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS11005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C6N15_RS11030	COG1051	belongs to the nudix hydrolase family
C6N15_RS11040	COG0668	transmembrane transport
C6N15_RS11045	COG2203	Gaf domain
C6N15_RS11045	COG4585	Histidine kinase
C6N15_RS11050	COG2197	response regulator
C6N15_RS11060	COG1064	alcohol dehydrogenase
C6N15_RS11085	COG1070	Carbohydrate kinase
C6N15_RS11090	COG1070	Carbohydrate kinase
C6N15_RS11120	COG1125	glycine betaine transport
C6N15_RS11120	COG0517	IMP dehydrogenase activity
C6N15_RS11125	COG1174	glycine betaine transport
C6N15_RS11160	COG1253	flavin adenine dinucleotide binding
C6N15_RS11165	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS11170	COG5506	Protein of unknown function (DUF1694)
C6N15_RS11185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6N15_RS11190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C6N15_RS11195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C6N15_RS11200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C6N15_RS11205	COG0456	acetyltransferase
C6N15_RS11210	COG3829	transcription factor binding
C6N15_RS11215	COG1509	lysine 2,3-aminomutase activity
C6N15_RS11255	COG4326	sporulation control protein
C6N15_RS11260	COG0671	phosphoesterase, PA-phosphatase related
C6N15_RS11265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C6N15_RS11270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6N15_RS11300	COG1787	Restriction endonuclease
C6N15_RS11300	COG1715	Restriction endonuclease
C6N15_RS11390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C6N15_RS11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N15_RS11430	COG4499	WXG100 protein secretion system (Wss), protein YukC
C6N15_RS11435	COG2814	Major facilitator Superfamily
C6N15_RS11440	COG4841	protein insertion into membrane
C6N15_RS11445	COG0372	Belongs to the citrate synthase family
C6N15_RS11450	COG2079	MmgE PrpD family protein
C6N15_RS11455	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C6N15_RS11460	COG1960	acyl-CoA dehydrogenase activity
C6N15_RS11465	COG2084	Dehydrogenase
C6N15_RS11475	COG1280	lysine exporter protein (LysE YggA)
C6N15_RS11480	COG1024	Enoyl-CoA hydratase
C6N15_RS11495	COG0420	3'-5' exonuclease activity
C6N15_RS11500	COG0419	ATPase involved in DNA repair
C6N15_RS11520	COG2223	nitrite transmembrane transporter activity
C6N15_RS11525	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS11530	COG1169	isochorismate synthase
C6N15_RS11535	COG1021	2,3-dihydroxybenzoate-AMP ligase
C6N15_RS11540	COG1535	isochorismatase
C6N15_RS11540	COG3433	isochorismatase activity
C6N15_RS11545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C6N15_RS11550	COG3251	PFAM MbtH domain protein
C6N15_RS11555	COG2814	Major facilitator Superfamily
C6N15_RS11570	COG0776	regulation of translation
C6N15_RS11580	COG2318	DinB family
C6N15_RS11590	COG1115	amino acid carrier protein
C6N15_RS11605	COG2329	Antibiotic biosynthesis monooxygenase
C6N15_RS11610	COG1187	pseudouridine synthase activity
C6N15_RS11615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C6N15_RS11630	COG0596	Alpha beta hydrolase
C6N15_RS11635	COG2814	Major facilitator Superfamily
C6N15_RS11655	COG2226	methyltransferase
C6N15_RS11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS11735	COG1247	-acetyltransferase
C6N15_RS11765	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C6N15_RS11775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS11785	COG1278	Cold shock
C6N15_RS11800	COG0010	Belongs to the arginase family
C6N15_RS11805	COG0561	phosphatase activity
C6N15_RS11845	COG0583	DNA-binding transcription factor activity
C6N15_RS11850	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6N15_RS11865	COG0583	DNA-binding transcription factor activity
C6N15_RS11870	COG2258	MOSC domain
C6N15_RS11885	COG1132	(ABC) transporter
C6N15_RS11890	COG1132	(ABC) transporter
C6N15_RS11910	COG1396	sequence-specific DNA binding
C6N15_RS11935	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C6N15_RS11940	COG1595	DNA-templated transcription, initiation
C6N15_RS11965	COG1649	PFAM Uncharacterised BCR, COG1649
C6N15_RS11990	COG2971	BadF BadG BcrA BcrD
C6N15_RS11995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C6N15_RS12000	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C6N15_RS12020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS12050	COG1309	transcriptional regulator
C6N15_RS12065	COG1136	(ABC) transporter
C6N15_RS12065	COG0577	efflux transmembrane transporter activity
C6N15_RS12070	COG0500	methyltransferase
C6N15_RS12070	COG3615	Tellurite resistance protein tehB
C6N15_RS12080	COG2226	methyltransferase
C6N15_RS12085	COG3961	Belongs to the TPP enzyme family
C6N15_RS12090	COG1846	Transcriptional regulator
C6N15_RS12130	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6N15_RS12145	COG1595	DNA-templated transcription, initiation
C6N15_RS12155	COG0768	penicillin binding
C6N15_RS12165	COG2367	Beta-lactamase
C6N15_RS12170	COG0671	phosphoesterase, PA-phosphatase related
C6N15_RS12175	COG1609	Transcriptional regulator
C6N15_RS12180	COG2814	Major facilitator Superfamily
C6N15_RS12185	COG0673	inositol 2-dehydrogenase activity
C6N15_RS12195	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS12210	COG0191	fructose-bisphosphate aldolase activity
C6N15_RS12215	COG3718	enzyme involved in inositol metabolism
C6N15_RS12240	COG0457	Tetratricopeptide repeat
C6N15_RS12245	COG1476	TRANSCRIPTIONal
C6N15_RS12260	COG1876	peptidase activity
C6N15_RS12280	COG1309	transcriptional regulator
C6N15_RS12285	COG0488	(ABC) transporter
C6N15_RS12300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS12315	COG1252	NADH dehydrogenase
C6N15_RS12320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N15_RS12335	COG1131	(ABC) transporter
C6N15_RS12345	COG1309	transcriptional regulator
C6N15_RS12360	COG1960	acyl-CoA dehydrogenase activity
C6N15_RS12365	COG0439	Biotin carboxylase
C6N15_RS12370	COG0511	ligase activity, forming carbon-carbon bonds
C6N15_RS12375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C6N15_RS12380	COG1024	Enoyl-CoA hydratase
C6N15_RS12385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C6N15_RS12390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N15_RS12400	COG1247	-acetyltransferase
C6N15_RS12405	COG0572	uridine kinase
C6N15_RS12415	COG2318	DinB family
C6N15_RS12420	COG1686	Belongs to the peptidase S11 family
C6N15_RS12445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C6N15_RS12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6N15_RS12485	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6N15_RS12510	COG2814	Major facilitator Superfamily
C6N15_RS12530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N15_RS12550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS12565	COG1063	alcohol dehydrogenase
C6N15_RS12595	COG3773	Cell wall hydrolase
C6N15_RS12605	COG0745	RESPONSE REGULATOR receiver
C6N15_RS12620	COG0488	(ABC) transporter
C6N15_RS12635	COG1136	(ABC) transporter
C6N15_RS12660	COG0460	homoserine dehydrogenase
C6N15_RS12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C6N15_RS12740	COG2124	cytochrome p450
C6N15_RS12775	COG0561	phosphatase activity
C6N15_RS12785	COG5002	protein histidine kinase activity
C6N15_RS12790	COG0768	penicillin binding
C6N15_RS12795	COG1819	glycosyl
C6N15_RS12800	COG1794	racemase activity, acting on amino acids and derivatives
C6N15_RS12810	COG1122	ATPase activity
C6N15_RS12825	COG2205	protein histidine kinase activity
C6N15_RS12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6N15_RS12840	COG0604	alcohol dehydrogenase
C6N15_RS12845	COG0768	penicillin binding
C6N15_RS12855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N15_RS12890	COG0693	protein deglycase activity
C6N15_RS12920	COG2814	Major facilitator Superfamily
C6N15_RS12935	COG0584	glycerophosphoryl diester phosphodiesterase
C6N15_RS12955	COG0697	spore germination
C6N15_RS12980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N15_RS12990	COG2223	nitrite transmembrane transporter activity
C6N15_RS13005	COG2816	NAD+ diphosphatase activity
C6N15_RS13010	COG0592	DNA-directed DNA polymerase activity
C6N15_RS13015	COG1051	belongs to the nudix hydrolase family
C6N15_RS13050	COG3878	Protein conserved in bacteria
C6N15_RS13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C6N15_RS13110	COG0322	excinuclease ABC activity
C6N15_RS13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N15_RS13175	COG1011	Hydrolase
C6N15_RS13195	COG0076	glutamate decarboxylase activity
C6N15_RS13210	COG1523	belongs to the glycosyl hydrolase 13 family
C6N15_RS13215	COG3227	Zinc metalloprotease (Elastase)
C6N15_RS13235	COG0201	protein transport
C6N15_RS13245	COG0697	spore germination
C6N15_RS13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS13285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS13300	COG2959	enzyme of heme biosynthesis
C6N15_RS13320	COG3483	tryptophan 2,3-dioxygenase activity
C6N15_RS13325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C6N15_RS13330	COG3844	kynureninase activity
C6N15_RS13335	COG1309	transcriptional regulator
C6N15_RS13365	COG3284	Transcriptional regulator
C6N15_RS13385	COG1349	DNA-binding transcription factor activity
C6N15_RS13405	COG1959	2 iron, 2 sulfur cluster binding
C6N15_RS13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N15_RS13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N15_RS13430	COG0022	dehydrogenase e1 component
C6N15_RS13435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6N15_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS13450	COG0456	acetyltransferase
C6N15_RS13450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6N15_RS13480	COG4176	ABC-type proline glycine betaine transport system permease component
C6N15_RS13485	COG0517	IMP dehydrogenase activity
C6N15_RS13485	COG4175	Glycine betaine
C6N15_RS13510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C6N15_RS13515	COG2153	protein acetylation
C6N15_RS13520	COG3397	chitin binding
C6N15_RS13535	COG2205	protein histidine kinase activity
C6N15_RS13560	COG2333	competence protein COMEC
C6N15_RS13560	COG0658	competence protein
C6N15_RS13610	COG3973	AAA domain
C6N15_RS13625	COG2105	PFAM AIG2 family protein
C6N15_RS13630	COG0514	ATP-dependent DNA helicase (RecQ)
C6N15_RS13650	COG4637	Psort location Cytoplasmic, score
C6N15_RS13675	COG3397	chitin binding
C6N15_RS13690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C6N15_RS13695	COG1115	amino acid carrier protein
C6N15_RS13700	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS13705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C6N15_RS13715	COG3938	Belongs to the proline racemase family
C6N15_RS13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C6N15_RS13760	COG0586	Pfam SNARE associated Golgi protein
C6N15_RS13775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C6N15_RS13780	COG0519	Catalyzes the synthesis of GMP from XMP
C6N15_RS13785	COG4166	transmembrane transport
C6N15_RS13795	COG4948	Mandelate Racemase Muconate Lactonizing
C6N15_RS13840	COG2936	dipeptidyl-peptidase activity
C6N15_RS13845	COG5002	protein histidine kinase activity
C6N15_RS13885	COG1164	Oligoendopeptidase f
C6N15_RS13900	COG1307	EDD domain protein, DegV family
C6N15_RS13920	COG2814	Major facilitator Superfamily
C6N15_RS13930	COG1664	Polymer-forming cytoskeletal
C6N15_RS13935	COG0789	Transcriptional regulator
C6N15_RS13940	COG4533	DNA binding
C6N15_RS13945	COG2814	Major facilitator Superfamily
C6N15_RS13945	COG0477	Major facilitator Superfamily
C6N15_RS13965	COG2261	transglycosylase associated protein
C6N15_RS13980	COG2226	methyltransferase
C6N15_RS14015	COG0436	Aminotransferase
C6N15_RS14020	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C6N15_RS14025	COG5146	pantothenate kinase activity
C6N15_RS14045	COG1131	(ABC) transporter
C6N15_RS14090	COG0628	permease
C6N15_RS14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N15_RS14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N15_RS14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N15_RS14115	COG1116	anion transmembrane transporter activity
C6N15_RS14135	COG2816	NAD+ diphosphatase activity
C6N15_RS14155	COG2746	aminoglycoside 3-N-acetyltransferase activity
C6N15_RS14180	COG0697	spore germination
C6N15_RS14185	COG2318	DinB family
C6N15_RS14205	COG4912	Dna alkylation repair
C6N15_RS14225	COG0861	Integral membrane protein TerC family
C6N15_RS14230	COG1368	sulfuric ester hydrolase activity
C6N15_RS14235	COG0488	(ABC) transporter
C6N15_RS14245	COG2409	Drug exporters of the RND superfamily
C6N15_RS14245	COG1033	growth of symbiont in host cell
C6N15_RS14250	COG1033	growth of symbiont in host cell
C6N15_RS14250	COG2409	Drug exporters of the RND superfamily
C6N15_RS14255	COG1033	growth of symbiont in host cell
C6N15_RS14255	COG2409	Drug exporters of the RND superfamily
C6N15_RS14260	COG1309	transcriptional regulator
C6N15_RS14275	COG0287	Prephenate dehydrogenase
C6N15_RS14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C6N15_RS14285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C6N15_RS14290	COG1605	Chorismate mutase
C6N15_RS14290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C6N15_RS14325	COG1388	LysM domain
C6N15_RS14325	COG3584	3D domain protein
C6N15_RS14335	COG1595	DNA-templated transcription, initiation
C6N15_RS14360	COG1879	ABC-type sugar transport system periplasmic component
C6N15_RS14370	COG1172	Belongs to the binding-protein-dependent transport system permease family
C6N15_RS14380	COG2390	Transcriptional regulator
C6N15_RS14415	COG2329	Antibiotic biosynthesis monooxygenase
C6N15_RS14435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS14445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C6N15_RS14450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N15_RS14455	COG4187	Peptidase family M20/M25/M40
C6N15_RS14460	COG1414	Transcriptional regulator
C6N15_RS14465	COG0833	amino acid
C6N15_RS14470	COG1690	Belongs to the RtcB family
C6N15_RS14475	COG3239	Fatty acid desaturase
C6N15_RS14480	COG1785	Belongs to the alkaline phosphatase family
C6N15_RS14490	COG3655	Transcriptional regulator
C6N15_RS14505	COG4377	Putative membrane peptidase family (DUF2324)
C6N15_RS14515	COG3279	Response regulator of the LytR AlgR family
C6N15_RS14525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS14530	COG0346	lactoylglutathione lyase activity
C6N15_RS14550	COG0714	Associated with various cellular activities
C6N15_RS14575	COG0463	Glycosyl transferase, family 2
C6N15_RS14595	COG0463	Glycosyl transferase, family 2
C6N15_RS14605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N15_RS14610	COG0753	catalase activity
C6N15_RS14620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C6N15_RS14645	COG0714	Associated with various cellular activities
C6N15_RS14655	COG0778	Nitroreductase
C6N15_RS14660	COG1846	Transcriptional regulator
C6N15_RS14695	COG1725	Transcriptional regulator
C6N15_RS14705	COG1136	(ABC) transporter
C6N15_RS14730	COG2207	Transcriptional regulator
C6N15_RS14735	COG0456	acetyltransferase
C6N15_RS14755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS14775	COG0642	Histidine kinase
C6N15_RS14780	COG0745	RESPONSE REGULATOR receiver
C6N15_RS14785	COG0596	Alpha beta hydrolase
C6N15_RS14815	COG0730	response to heat
C6N15_RS14825	COG0833	amino acid
C6N15_RS14835	COG4335	DNA alkylation repair
C6N15_RS14875	COG0768	penicillin binding
C6N15_RS14885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C6N15_RS14915	COG1984	allophanate hydrolase subunit 2
C6N15_RS14920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C6N15_RS14925	COG1414	Transcriptional regulator
C6N15_RS14940	COG0860	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS14945	COG0640	Transcriptional regulator
C6N15_RS14955	COG1960	acyl-CoA dehydrogenase activity
C6N15_RS14970	COG3314	Sporulation integral membrane protein YlbJ
C6N15_RS14985	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C6N15_RS15000	COG3848	Pyruvate phosphate dikinase
C6N15_RS15000	COG0574	Belongs to the PEP-utilizing enzyme family
C6N15_RS15005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS15020	COG5577	PFAM Coat F domain
C6N15_RS15025	COG3403	YqcI/YcgG family
C6N15_RS15030	COG1280	lysine exporter protein (LysE YggA)
C6N15_RS15065	COG1063	alcohol dehydrogenase
C6N15_RS15080	COG1027	Aspartate ammonia-lyase
C6N15_RS15085	COG0252	asparaginase activity
C6N15_RS15090	COG1396	sequence-specific DNA binding
C6N15_RS15100	COG0322	excinuclease ABC activity
C6N15_RS15105	COG0531	amino acid
C6N15_RS15110	COG1114	Component of the transport system for branched-chain amino acids
C6N15_RS15115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N15_RS15125	COG0281	malic enzyme
C6N15_RS15140	COG0531	amino acid
C6N15_RS15150	COG0784	Response regulator, receiver
C6N15_RS15160	COG2066	Belongs to the glutaminase family
C6N15_RS15165	COG1115	amino acid carrier protein
C6N15_RS15195	COG0737	Belongs to the 5'-nucleotidase family
C6N15_RS15200	COG0753	catalase activity
C6N15_RS15205	COG2267	carboxylic ester hydrolase activity
C6N15_RS15210	COG1335	isochorismatase
C6N15_RS15230	COG0583	DNA-binding transcription factor activity
C6N15_RS15235	COG1846	Transcriptional regulator
C6N15_RS15275	COG0415	Belongs to the DNA photolyase family
C6N15_RS15280	COG0288	reversible hydration of carbon dioxide
C6N15_RS15290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N15_RS15295	COG5609	conserved protein (DUF2294)
C6N15_RS15310	COG1575	Belongs to the MenA family. Type 1 subfamily
C6N15_RS15315	COG2267	carboxylic ester hydrolase activity
C6N15_RS15320	COG0803	Belongs to the bacterial solute-binding protein 9 family
C6N15_RS15325	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N15_RS15330	COG1121	(ABC) transporter
C6N15_RS15360	COG0798	PFAM Bile acid sodium symporter
C6N15_RS15365	COG0346	lactoylglutathione lyase activity
C6N15_RS15370	COG0640	Transcriptional regulator
C6N15_RS15385	COG0443	Heat shock 70 kDa protein
C6N15_RS15400	COG1522	sequence-specific DNA binding
C6N15_RS15415	COG0346	lactoylglutathione lyase activity
C6N15_RS15440	COG2169	Transcriptional regulator
C6N15_RS15485	COG2814	Major facilitator Superfamily
C6N15_RS15510	COG0745	RESPONSE REGULATOR receiver
C6N15_RS15515	COG5002	protein histidine kinase activity
C6N15_RS15515	COG3850	Histidine kinase
C6N15_RS15540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C6N15_RS15560	COG1476	TRANSCRIPTIONal
C6N15_RS15575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS15580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C6N15_RS15590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N15_RS15595	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C6N15_RS15610	COG1136	(ABC) transporter
C6N15_RS15615	COG0577	efflux transmembrane transporter activity
C6N15_RS15630	COG3850	Histidine kinase
C6N15_RS15630	COG5002	protein histidine kinase activity
C6N15_RS15640	COG2364	Membrane
C6N15_RS15645	COG1846	Transcriptional regulator
C6N15_RS15655	COG2808	Putative FMN-binding domain
C6N15_RS15660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS15665	COG2271	Major facilitator Superfamily
C6N15_RS15670	COG1556	Lactate utilization protein
C6N15_RS15675	COG1139	Iron-sulfur cluster binding protein
C6N15_RS15685	COG0583	DNA-binding transcription factor activity
C6N15_RS15695	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6N15_RS15715	COG0738	Major facilitator superfamily
C6N15_RS15720	COG0673	inositol 2-dehydrogenase activity
C6N15_RS15725	COG0561	phosphatase activity
C6N15_RS15735	COG1609	Transcriptional regulator
C6N15_RS15740	COG0457	Tetratricopeptide repeat
C6N15_RS15760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N15_RS15790	COG0534	Mate efflux family protein
C6N15_RS15810	COG2814	Major facilitator Superfamily
C6N15_RS15815	COG1309	transcriptional regulator
C6N15_RS15830	COG0814	amino acid
C6N15_RS15835	COG1760	l-serine dehydratase
C6N15_RS15840	COG1760	l-serine dehydratase
C6N15_RS15850	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C6N15_RS15855	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C6N15_RS15865	COG1335	isochorismatase
C6N15_RS15870	COG1522	sequence-specific DNA binding
C6N15_RS15875	COG0531	amino acid
C6N15_RS15890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C6N15_RS15910	COG1595	DNA-templated transcription, initiation
C6N15_RS15925	COG0662	Cupin 2, conserved barrel domain protein
C6N15_RS15930	COG2207	Transcriptional regulator
C6N15_RS15930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS15980	COG0477	Major facilitator Superfamily
C6N15_RS15990	COG1846	Transcriptional regulator
C6N15_RS15995	COG2814	Major facilitator Superfamily
C6N15_RS16005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C6N15_RS16010	COG1131	(ABC) transporter
C6N15_RS16030	COG2076	Multidrug Resistance protein
C6N15_RS16035	COG1309	transcriptional regulator
C6N15_RS16045	COG2031	fatty acid transporter
C6N15_RS16055	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N15_RS16085	COG1122	ATPase activity
C6N15_RS16090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C6N15_RS16105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C6N15_RS16110	COG1288	antiporter activity
C6N15_RS16115	COG2356	endonuclease I
C6N15_RS16130	COG3620	sequence-specific DNA binding
C6N15_RS16135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C6N15_RS16140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C6N15_RS16145	COG0124	histidyl-tRNA synthetase
C6N15_RS16160	COG1733	regulation of RNA biosynthetic process
C6N15_RS16165	COG0778	Nitroreductase
C6N15_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS16195	COG1131	(ABC) transporter
C6N15_RS16220	COG1011	Hydrolase
C6N15_RS16230	COG2365	Tyrosine phosphatase family
C6N15_RS16255	COG0346	lactoylglutathione lyase activity
C6N15_RS16260	COG1940	carbohydrate kinase activity
C6N15_RS16265	COG0738	Major facilitator superfamily
C6N15_RS16270	COG0110	maltose O-acetyltransferase activity
C6N15_RS16280	COG0577	efflux transmembrane transporter activity
C6N15_RS16280	COG1136	(ABC) transporter
C6N15_RS16295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C6N15_RS16300	COG0628	permease
C6N15_RS16320	COG2226	methyltransferase
C6N15_RS16330	COG0477	Major facilitator Superfamily
C6N15_RS16360	COG1253	flavin adenine dinucleotide binding
C6N15_RS16365	COG0789	Transcriptional regulator
C6N15_RS16370	COG0697	spore germination
C6N15_RS16375	COG1357	PFAM Pentapeptide repeats (8 copies)
C6N15_RS16380	COG3813	Protein conserved in bacteria
C6N15_RS16385	COG2706	6-phosphogluconolactonase activity
C6N15_RS16390	COG1070	Carbohydrate kinase
C6N15_RS16400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C6N15_RS16405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
C6N15_RS16415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6N15_RS16420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C6N15_RS16425	COG0604	alcohol dehydrogenase
C6N15_RS16430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C6N15_RS16440	COG3321	synthase
C6N15_RS16440	COG0604	alcohol dehydrogenase
C6N15_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS16470	COG0656	L-ascorbic acid biosynthetic process
C6N15_RS16475	COG2814	Major facilitator Superfamily
C6N15_RS16490	COG0346	lactoylglutathione lyase activity
C6N15_RS16495	COG0814	amino acid
C6N15_RS16520	COG1393	Belongs to the ArsC family
C6N15_RS16525	COG1733	regulation of RNA biosynthetic process
C6N15_RS16530	COG2188	Transcriptional regulator
C6N15_RS16540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C6N15_RS16545	COG1733	regulation of RNA biosynthetic process
C6N15_RS16550	COG1733	regulation of RNA biosynthetic process
C6N15_RS16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS16585	COG0384	phenazine biosynthesis protein PhzF
C6N15_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS16605	COG0318	PFAM AMP-dependent synthetase and ligase
C6N15_RS16615	COG1733	regulation of RNA biosynthetic process
C6N15_RS16650	COG1191	sigma factor activity
C6N15_RS16665	COG1309	transcriptional regulator
C6N15_RS16685	COG3152	Membrane
C6N15_RS16710	COG1151	hydroxylamine reductase activity
C6N15_RS16720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS16725	COG3409	Peptidoglycan-binding domain 1 protein
C6N15_RS16725	COG3757	hydrolase, family 25
C6N15_RS16760	COG2072	flavoprotein involved in K transport
C6N15_RS16795	COG0604	alcohol dehydrogenase
C6N15_RS16800	COG1113	amino acid transport
C6N15_RS16805	COG2814	Major facilitator Superfamily
C6N15_RS16835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6N15_RS16840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6N15_RS16860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS16865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS16875	COG3739	integral membrane protein
C6N15_RS16880	COG0384	phenazine biosynthesis protein PhzF
C6N15_RS16910	COG0583	DNA-binding transcription factor activity
C6N15_RS16930	COG1193	negative regulation of DNA recombination
C6N15_RS16955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C6N15_RS16985	COG0584	glycerophosphoryl diester phosphodiesterase
C6N15_RS17010	COG0640	Transcriptional regulator
C6N15_RS17015	COG0604	alcohol dehydrogenase
C6N15_RS17035	COG2808	Putative FMN-binding domain
C6N15_RS17040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6N15_RS17050	COG0385	Bile acid
C6N15_RS17055	COG0277	FAD linked oxidase domain protein
C6N15_RS17085	COG1216	Glycosyl transferase, family 2
C6N15_RS17090	COG1024	Enoyl-CoA hydratase
C6N15_RS17100	COG1285	pathogenesis
C6N15_RS17115	COG2514	catechol 2,3-dioxygenase activity
C6N15_RS17120	COG2720	vancomycin resistance protein
C6N15_RS17160	COG0716	FMN binding
C6N15_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS17200	COG0165	Argininosuccinate lyase
C6N15_RS17215	COG4145	pantothenate transmembrane transporter activity
C6N15_RS17220	COG3924	membrane
C6N15_RS17225	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS17240	COG1657	PFAM Prenyltransferase squalene oxidase
C6N15_RS17245	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C6N15_RS17250	COG2962	Rard protein
C6N15_RS17255	COG3326	Membrane
C6N15_RS17270	COG0489	protein tyrosine kinase activity
C6N15_RS17280	COG0314	molybdopterin synthase activity
C6N15_RS17285	COG0303	'Molybdopterin
C6N15_RS17290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6N15_RS17295	COG2116	formate transmembrane transporter activity
C6N15_RS17305	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C6N15_RS17310	COG5609	conserved protein (DUF2294)
C6N15_RS17315	COG2427	Protein of unknown function (DUF1641)
C6N15_RS17320	COG3383	formate dehydrogenase (NAD+) activity
C6N15_RS17325	COG0697	spore germination
C6N15_RS17365	COG2226	methyltransferase
C6N15_RS17370	COG4166	transmembrane transport
C6N15_RS17375	COG4166	transmembrane transport
C6N15_RS17380	COG4166	transmembrane transport
C6N15_RS17385	COG1301	dicarboxylic acid transport
C6N15_RS17390	COG1316	TRANSCRIPTIONal
C6N15_RS17400	COG1595	DNA-templated transcription, initiation
C6N15_RS17420	COG1131	(ABC) transporter
C6N15_RS17430	COG0673	inositol 2-dehydrogenase activity
C6N15_RS17435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C6N15_RS17440	COG0187	DNA topoisomerase II activity
C6N15_RS17445	COG1832	CoA-binding protein
C6N15_RS17450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N15_RS17455	COG0745	RESPONSE REGULATOR receiver
C6N15_RS17470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C6N15_RS17475	COG4841	protein insertion into membrane
C6N15_RS17480	COG0824	Thioesterase
C6N15_RS17510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6N15_RS17520	COG2274	protein secretion by the type I secretion system
C6N15_RS17525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C6N15_RS17565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6N15_RS17580	COG0183	Belongs to the thiolase family
C6N15_RS17585	COG0318	PFAM AMP-dependent synthetase and ligase
C6N15_RS17590	COG1268	BioY protein
C6N15_RS17595	COG0318	PFAM AMP-dependent synthetase and ligase
C6N15_RS17645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS17655	COG5002	protein histidine kinase activity
C6N15_RS17660	COG0400	carboxylic ester hydrolase activity
C6N15_RS17665	COG0346	lactoylglutathione lyase activity
C6N15_RS17670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C6N15_RS17675	COG0069	glutamate synthase activity
C6N15_RS17680	COG1902	pentaerythritol trinitrate reductase activity
C6N15_RS17685	COG1329	Transcriptional regulator
C6N15_RS17690	COG0010	Belongs to the arginase family
C6N15_RS17715	COG2226	methyltransferase
C6N15_RS17770	COG4846	Membrane protein involved in cytochrome C biogenesis
C6N15_RS17775	COG0785	Cytochrome C biogenesis protein
C6N15_RS17785	COG0583	DNA-binding transcription factor activity
C6N15_RS17790	COG1380	Effector of murein hydrolase LrgA
C6N15_RS17795	COG1346	cytolysis
C6N15_RS17820	COG3409	Peptidoglycan-binding domain 1 protein
C6N15_RS17820	COG5632	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS17835	COG1132	(ABC) transporter
C6N15_RS17840	COG1132	(ABC) transporter
C6N15_RS17870	COG3639	organic phosphonate transmembrane transporter activity
C6N15_RS17875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C6N15_RS17895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C6N15_RS17915	COG1695	Transcriptional regulator
C6N15_RS17950	COG1388	LysM domain
C6N15_RS17950	COG3409	Peptidoglycan-binding domain 1 protein
C6N15_RS17950	COG5632	N-Acetylmuramoyl-L-alanine amidase
C6N15_RS17955	COG4824	toxin secretion phage lysis holin
C6N15_RS18110	COG1595	DNA-templated transcription, initiation
C6N15_RS18155	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
C6N15_RS18235	COG1396	sequence-specific DNA binding
C6N15_RS18260	COG0174	glutamine synthetase
C6N15_RS18265	COG0789	Transcriptional regulator
C6N15_RS18270	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C6N15_RS18280	COG2860	membrane
C6N15_RS18290	COG0464	growth
C6N15_RS18320	COG3584	3D domain protein
C6N15_RS18320	COG1388	LysM domain
C6N15_RS18325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N15_RS18325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N15_RS18325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C6N15_RS18330	COG1105	Belongs to the carbohydrate kinase PfkB family
C6N15_RS18335	COG1349	DNA-binding transcription factor activity
C6N15_RS18345	COG2322	membrane
C6N15_RS18355	COG1113	amino acid transport
C6N15_RS18370	COG1408	metallophosphoesterase
C6N15_RS18375	COG2116	formate transmembrane transporter activity
C6N15_RS18385	COG2217	Heavy metal translocating P-type atpase
C6N15_RS18390	COG2608	mercury ion transmembrane transporter activity
C6N15_RS18395	COG1937	Protein conserved in bacteria
C6N15_RS18405	COG2819	hydrolase of the alpha beta superfamily
C6N15_RS18410	COG1120	ATPase activity
C6N15_RS18415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS18420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS18430	COG0708	Exodeoxyribonuclease III
C6N15_RS18435	COG2169	Transcriptional regulator
C6N15_RS18440	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C6N15_RS18445	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C6N15_RS18455	COG2364	Membrane
C6N15_RS18470	COG2267	carboxylic ester hydrolase activity
C6N15_RS18475	COG0346	lactoylglutathione lyase activity
C6N15_RS18480	COG3300	MHYT domain
C6N15_RS18480	COG5001	Diguanylate cyclase
C6N15_RS18495	COG1346	cytolysis
C6N15_RS18500	COG1380	Effector of murein hydrolase LrgA
C6N15_RS18505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C6N15_RS18510	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N15_RS18510	COG0596	Alpha beta hydrolase
C6N15_RS18515	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C6N15_RS18535	COG1404	Belongs to the peptidase S8 family
C6N15_RS18540	COG3773	Cell wall hydrolase
C6N15_RS18545	COG0562	UDP-galactopyranose mutase
C6N15_RS18550	COG1368	sulfuric ester hydrolase activity
C6N15_RS18555	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C6N15_RS18565	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C6N15_RS18590	COG1131	(ABC) transporter
C6N15_RS18610	COG4550	Control of competence regulator ComK, YlbF/YmcA
C6N15_RS18615	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C6N15_RS18620	COG1013	pyruvate-flavodoxin oxidoreductase activity
C6N15_RS18625	COG0674	pyruvate-flavodoxin oxidoreductase activity
C6N15_RS18625	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C6N15_RS18635	COG2359	stage V sporulation protein S
C6N15_RS18640	COG1692	metallophosphoesterase
C6N15_RS18665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C6N15_RS18670	COG1426	Protein conserved in bacteria
C6N15_RS18685	COG0300	oxidoreductase activity
C6N15_RS18690	COG0612	Peptidase, M16
C6N15_RS18695	COG0612	Peptidase, M16
C6N15_RS18700	COG1079	Belongs to the binding-protein-dependent transport system permease family
C6N15_RS18710	COG3845	ABC transporter
C6N15_RS18715	COG1744	ABC transporter substrate-binding protein PnrA-like
C6N15_RS18720	COG2188	Transcriptional regulator
C6N15_RS18725	COG1674	ftsk spoiiie
C6N15_RS18735	COG0740	serine-type endopeptidase activity
C6N15_RS18740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C6N15_RS18750	COG0527	aspartate kinase activity
C6N15_RS18755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C6N15_RS18760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6N15_RS18765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6N15_RS18770	COG1873	PFAM PRC-barrel domain
C6N15_RS18775	COG0612	Peptidase, M16
C6N15_RS18780	COG0726	polysaccharide deacetylase
C6N15_RS18795	COG0196	riboflavin kinase activity
C6N15_RS18800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C6N15_RS18810	COG1550	Protein conserved in bacteria
C6N15_RS18820	COG1358	cellular component organization or biogenesis
C6N15_RS18825	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C6N15_RS18830	COG0195	Participates in both transcription termination and antitermination
C6N15_RS18850	COG0750	zinc metalloprotease
C6N15_RS18860	COG4589	Belongs to the CDS family
C6N15_RS18865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C6N15_RS18875	COG0528	UMP kinase activity
C6N15_RS18905	COG4974	Belongs to the 'phage' integrase family
C6N15_RS18915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C6N15_RS18925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C6N15_RS18965	COG1837	Belongs to the UPF0109 family
C6N15_RS18975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C6N15_RS18985	COG0552	protein localization to endoplasmic reticulum
C6N15_RS18990	COG1196	nuclear chromosome segregation
C6N15_RS19000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C6N15_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS19010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C6N15_RS19025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C6N15_RS19030	COG1461	Dihydroxyacetone kinase
C6N15_RS19035	COG1302	Protein conserved in bacteria
C6N15_RS19050	COG1564	THIamine pyrophosphokinase
C6N15_RS19055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C6N15_RS19060	COG1162	GTPase activity
C6N15_RS19065	COG0515	serine threonine protein kinase
C6N15_RS19065	COG2815	serine threonine protein kinase
C6N15_RS19070	COG0631	protein serine/threonine phosphatase activity
C6N15_RS19080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C6N15_RS19080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C6N15_RS19090	COG0242	peptide deformylase activity
C6N15_RS19095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C6N15_RS19100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C6N15_RS19120	COG1561	YicC-like family, N-terminal region
C6N15_RS19125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C6N15_RS19135	COG0006	proline dipeptidase activity
C6N15_RS19150	COG3069	C4-dicarboxylate transmembrane transporter activity
C6N15_RS19215	COG0564	pseudouridine synthase activity
C6N15_RS19235	COG3599	regulation of cell shape
C6N15_RS19240	COG2302	S4 RNA-binding domain
C6N15_RS19245	COG0762	integral membrane protein
C6N15_RS19255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C6N15_RS19260	COG1496	oxidoreductase activity
C6N15_RS19265	COG1873	PFAM PRC-barrel domain
C6N15_RS19270	COG1191	sigma factor activity
C6N15_RS19275	COG1191	sigma factor activity
C6N15_RS19285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C6N15_RS19290	COG0849	cell division
C6N15_RS19295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C6N15_RS19300	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C6N15_RS19310	COG0772	Belongs to the SEDS family
C6N15_RS19325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C6N15_RS19330	COG0768	penicillin binding
C6N15_RS19335	COG0768	penicillin binding
C6N15_RS19340	COG4839	cell division protein FtsL
C6N15_RS19355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C6N15_RS19370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C6N15_RS19375	COG1399	metal-binding, possibly nucleic acid-binding protein
C6N15_RS19425	COG4824	toxin secretion phage lysis holin
C6N15_RS19510	COG1802	Transcriptional regulator
C6N15_RS19510	COG4626	Terminase
C6N15_RS19535	COG0582	viral genome integration into host DNA
C6N15_RS19600	COG0756	dUTP diphosphatase activity
C6N15_RS19615	COG1191	sigma factor activity
C6N15_RS19640	COG1484	DNA-dependent DNA replication
C6N15_RS19670	COG1396	sequence-specific DNA binding
C6N15_RS19685	COG1396	sequence-specific DNA binding
C6N15_RS19700	COG0582	viral genome integration into host DNA
C6N15_RS19710	COG3480	Lon protease (S16) C-terminal proteolytic domain
C6N15_RS19715	COG1752	Esterase of the alpha-beta hydrolase superfamily
C6N15_RS19720	COG3314	Sporulation integral membrane protein YlbJ
C6N15_RS19730	COG0742	ribosomal rna small subunit methyltransferase
C6N15_RS19745	COG3679	Belongs to the UPF0342 family
C6N15_RS19750	COG0406	alpha-ribazole phosphatase activity
C6N15_RS19765	COG2340	Cysteine-rich secretory protein family
C6N15_RS19780	COG3336	cytochrome c oxidase
C6N15_RS19820	COG0772	Belongs to the SEDS family
C6N15_RS19830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C6N15_RS19835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C6N15_RS19845	COG4896	Protein conserved in bacteria
C6N15_RS19860	COG1217	gtp-binding protein TYPA
C6N15_RS19870	COG0483	inositol monophosphate 1-phosphatase activity
C6N15_RS19890	COG1982	Orn Lys Arg decarboxylase major
C6N15_RS19935	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N15_RS19940	COG0022	dehydrogenase e1 component
C6N15_RS19945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6N15_RS19955	COG0242	peptide deformylase activity
C6N15_RS19960	COG0561	phosphatase activity
C6N15_RS19970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C6N15_RS19975	COG0569	domain protein
C6N15_RS19995	COG0583	DNA-binding transcription factor activity
C6N15_RS20000	COG0517	IMP dehydrogenase activity
C6N15_RS20010	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C6N15_RS20020	COG4703	Protein of unknown function (DUF1797)
C6N15_RS20035	COG2200	EAL domain
C6N15_RS20040	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS20045	COG1408	metallophosphoesterase
C6N15_RS20055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C6N15_RS20090	COG2814	Major facilitator Superfamily
C6N15_RS20110	COG3209	COG3209 Rhs family protein
C6N15_RS20120	COG2205	protein histidine kinase activity
C6N15_RS20130	COG0436	Aminotransferase
C6N15_RS20135	COG1609	Transcriptional regulator
C6N15_RS20140	COG3833	ABC-type maltose transport systems, permease component
C6N15_RS20145	COG1175	transmembrane transport
C6N15_RS20150	COG2182	Extracellular solute-binding protein
C6N15_RS20160	COG0366	Alpha amylase catalytic
C6N15_RS20165	COG3842	ATPase activity
C6N15_RS20205	COG0183	Belongs to the thiolase family
C6N15_RS20240	COG1695	Transcriptional regulator
C6N15_RS20245	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS20255	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C6N15_RS20265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C6N15_RS20270	COG0436	Aminotransferase
C6N15_RS20290	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C6N15_RS20310	COG2199	diguanylate cyclase activity
C6N15_RS20315	COG0778	Nitroreductase
C6N15_RS20340	COG1263	PTS System
C6N15_RS20340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C6N15_RS20340	COG2190	(PTS) system
C6N15_RS20345	COG3711	transcriptional antiterminator
C6N15_RS20355	COG2188	Transcriptional regulator
C6N15_RS20365	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C6N15_RS20390	COG1547	Domain of unknown function (DUF309)
C6N15_RS20395	COG0456	acetyltransferase
C6N15_RS20400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C6N15_RS20405	COG4086	secreted protein
C6N15_RS20410	COG0561	phosphatase activity
C6N15_RS20415	COG0697	spore germination
C6N15_RS20430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N15_RS20455	COG0733	neurotransmitter:sodium symporter activity
C6N15_RS20475	COG1686	Belongs to the peptidase S11 family
C6N15_RS20480	COG1725	Transcriptional regulator
C6N15_RS20485	COG1131	(ABC) transporter
C6N15_RS20500	COG1846	Transcriptional regulator
C6N15_RS20515	COG0598	Magnesium transport protein CorA
C6N15_RS20550	COG0735	belongs to the Fur family
C6N15_RS20555	COG1300	Membrane
C6N15_RS20575	COG0667	Aldo Keto reductase
C6N15_RS20580	COG0656	L-ascorbic acid biosynthetic process
C6N15_RS20585	COG0456	acetyltransferase
C6N15_RS20585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C6N15_RS20595	COG4085	toxin activity
C6N15_RS20595	COG0737	Belongs to the 5'-nucleotidase family
C6N15_RS20595	COG1525	nuclease
C6N15_RS20605	COG0596	Alpha beta hydrolase
C6N15_RS20610	COG2056	Na+-H+ antiporter family
C6N15_RS20620	COG0456	acetyltransferase
C6N15_RS20625	COG1073	alpha beta
C6N15_RS20640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N15_RS20640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C6N15_RS20645	COG0307	riboflavin synthase, alpha
C6N15_RS20670	COG4106	trans-aconitate 2-methyltransferase activity
C6N15_RS20675	COG1073	alpha beta
C6N15_RS20675	COG2226	methyltransferase
C6N15_RS20690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C6N15_RS20700	COG1757	Na H antiporter
C6N15_RS20705	COG0737	Belongs to the 5'-nucleotidase family
C6N15_RS20715	COG1522	sequence-specific DNA binding
C6N15_RS20735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C6N15_RS20745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C6N15_RS20760	COG0300	oxidoreductase activity
C6N15_RS20770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N15_RS20775	COG1760	l-serine dehydratase
C6N15_RS20780	COG1760	l-serine dehydratase
C6N15_RS20800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C6N15_RS20810	COG2195	Cleaves the N-terminal amino acid of tripeptides
C6N15_RS20815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS20830	COG1376	ErfK ybiS ycfS ynhG family protein
C6N15_RS20835	COG4129	membrane
C6N15_RS20840	COG1126	abc transporter atp-binding protein
C6N15_RS20845	COG0765	amino acid transport
C6N15_RS20850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C6N15_RS20870	COG0772	Belongs to the SEDS family
C6N15_RS20875	COG0508	dehydrogenase complex catalyzes the overall conversion of
C6N15_RS20880	COG0022	dehydrogenase e1 component
C6N15_RS20885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C6N15_RS20890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C6N15_RS20905	COG0280	phosphate acetyltransferase
C6N15_RS20910	COG3290	protein histidine kinase activity
C6N15_RS20910	COG3829	transcription factor binding
C6N15_RS20920	COG0584	glycerophosphoryl diester phosphodiesterase
C6N15_RS20925	COG3093	addiction module antidote protein HigA
C6N15_RS20935	COG0745	RESPONSE REGULATOR receiver
C6N15_RS20940	COG0750	zinc metalloprotease
C6N15_RS20945	COG0497	DNA recombination
C6N15_RS20955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C6N15_RS20965	COG0142	geranyltranstransferase activity
C6N15_RS20990	COG1302	Protein conserved in bacteria
C6N15_RS20995	COG0439	Biotin carboxylase
C6N15_RS21000	COG0511	ligase activity, forming carbon-carbon bonds
C6N15_RS21045	COG3854	ATPases associated with a variety of cellular activities
C6N15_RS21070	COG0006	proline dipeptidase activity
C6N15_RS21085	COG3872	metal-dependent enzyme
C6N15_RS21095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C6N15_RS21115	COG0095	Lipoate-protein ligase
C6N15_RS21120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N15_RS21125	COG1609	Transcriptional regulator
C6N15_RS21135	COG2076	Multidrug Resistance protein
C6N15_RS21140	COG2076	Multidrug Resistance protein
C6N15_RS21175	COG1131	(ABC) transporter
C6N15_RS21180	COG1725	Transcriptional regulator
C6N15_RS21210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C6N15_RS21265	COG4970	Tfp pilus assembly protein FimT
C6N15_RS21275	COG1459	type II secretion system
C6N15_RS21280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C6N15_RS21330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C6N15_RS21335	COG1410	methionine synthase
C6N15_RS21335	COG0646	methionine synthase
C6N15_RS21340	COG0646	methionine synthase
C6N15_RS21340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C6N15_RS21345	COG0626	cystathionine gamma-synthase activity
C6N15_RS21350	COG0626	cystathionine gamma-synthase activity
C6N15_RS21370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS21380	COG1940	carbohydrate kinase activity
C6N15_RS21385	COG4483	Protein conserved in bacteria
C6N15_RS21390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C6N15_RS21395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C6N15_RS21400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C6N15_RS21405	COG0704	Plays a role in the regulation of phosphate uptake
C6N15_RS21415	COG0581	inorganic phosphate transmembrane transporter activity
C6N15_RS21420	COG0573	inorganic phosphate transmembrane transporter activity
C6N15_RS21425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C6N15_RS21430	COG0768	penicillin binding
C6N15_RS21435	COG0477	Major facilitator Superfamily
C6N15_RS21440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N15_RS21465	COG0735	belongs to the Fur family
C6N15_RS21470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C6N15_RS21475	COG1121	(ABC) transporter
C6N15_RS21480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS21510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N15_RS21515	COG2384	SAM-dependent methyltransferase
C6N15_RS21520	COG2010	Cytochrome c
C6N15_RS21525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C6N15_RS21530	COG0358	DNA primase activity
C6N15_RS21540	COG0517	IMP dehydrogenase activity
C6N15_RS21555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C6N15_RS21560	COG0295	cytidine deaminase activity
C6N15_RS21565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C6N15_RS21575	COG1480	7TM receptor with intracellular HD hydrolase
C6N15_RS21580	COG1702	phosphate starvation-inducible protein PhoH
C6N15_RS21595	COG1610	YqeY-like protein
C6N15_RS21600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C6N15_RS21605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C6N15_RS21610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C6N15_RS21640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C6N15_RS21645	COG1733	regulation of RNA biosynthetic process
C6N15_RS21670	COG1466	dna polymerase III delta subunit
C6N15_RS21680	COG0658	competence protein
C6N15_RS21680	COG2333	competence protein COMEC
C6N15_RS21685	COG2131	deaminase
C6N15_RS21690	COG1596	polysaccharide export
C6N15_RS21690	COG1555	photosystem II stabilization
C6N15_RS21695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C6N15_RS21700	COG2226	methyltransferase
C6N15_RS21705	COG0799	negative regulation of ribosome biogenesis
C6N15_RS21710	COG1713	HD superfamily hydrolase involved in NAD metabolism
C6N15_RS21720	COG1534	Rna-binding protein
C6N15_RS21730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C6N15_RS21735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C6N15_RS21760	COG1595	DNA-templated transcription, initiation
C6N15_RS21770	COG0778	Nitroreductase
C6N15_RS21775	COG2357	RelA SpoT domain protein
C6N15_RS21785	COG1785	Belongs to the alkaline phosphatase family
C6N15_RS21795	COG2267	carboxylic ester hydrolase activity
C6N15_RS21830	COG1404	Belongs to the peptidase S8 family
C6N15_RS21835	COG3186	Phenylalanine-4-hydroxylase
C6N15_RS21850	COG2259	Doxx family
C6N15_RS21890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS21900	COG1012	belongs to the aldehyde dehydrogenase family
C6N15_RS21900	COG1454	alcohol dehydrogenase
C6N15_RS21905	COG0626	cystathionine gamma-synthase activity
C6N15_RS21910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C6N15_RS21935	COG0768	penicillin binding
C6N15_RS21950	COG0826	peptidase U32
C6N15_RS21955	COG0826	peptidase U32
C6N15_RS21960	COG4122	O-methyltransferase activity
C6N15_RS21965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C6N15_RS21985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C6N15_RS21995	COG0628	permease
C6N15_RS22015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C6N15_RS22025	COG0482	sulfurtransferase activity
C6N15_RS22030	COG1104	cysteine desulfurase activity
C6N15_RS22035	COG1959	2 iron, 2 sulfur cluster binding
C6N15_RS22040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C6N15_RS22050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C6N15_RS22075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C6N15_RS22085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C6N15_RS22085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C6N15_RS22090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C6N15_RS22095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6N15_RS22095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C6N15_RS22105	COG2244	polysaccharide biosynthetic process
C6N15_RS22110	COG2323	membrane
C6N15_RS22120	COG1862	Preprotein translocase
C6N15_RS22150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C6N15_RS22160	COG0697	spore germination
C6N15_RS22165	COG0697	spore germination
C6N15_RS22170	COG0640	Transcriptional regulator
C6N15_RS22200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C6N15_RS22205	COG1104	cysteine desulfurase activity
C6N15_RS22210	COG1827	regulation of RNA biosynthetic process
C6N15_RS22215	COG2258	MOSC domain
C6N15_RS22220	COG0077	Prephenate dehydratase
C6N15_RS22225	COG0577	efflux transmembrane transporter activity
C6N15_RS22230	COG0577	efflux transmembrane transporter activity
C6N15_RS22235	COG1136	(ABC) transporter
C6N15_RS22245	COG0745	RESPONSE REGULATOR receiver
C6N15_RS22250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C6N15_RS22255	COG3290	protein histidine kinase activity
C6N15_RS22265	COG2868	ribosomal protein
C6N15_RS22275	COG1530	ribonuclease E activity
C6N15_RS22280	COG1994	Peptidase M50
C6N15_RS22285	COG0739	heme binding
C6N15_RS22290	COG2894	cell division
C6N15_RS22310	COG1077	Cell shape determining protein MreB Mrl
C6N15_RS22330	COG0285	dihydrofolate synthase activity
C6N15_RS22335	COG0525	valine-tRNA ligase activity
C6N15_RS22345	COG1388	LysM domain
C6N15_RS22355	COG0113	porphobilinogen synthase activity
C6N15_RS22370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C6N15_RS22380	COG1846	Transcriptional regulator
C6N15_RS22385	COG1764	response to oxidative stress
C6N15_RS22400	COG0470	DNA polymerase III
C6N15_RS22400	COG1067	ATP-dependent peptidase activity
C6N15_RS22445	COG0622	Phosphoesterase
C6N15_RS22460	COG5401	PFAM Sporulation and spore germination
C6N15_RS22480	COG1309	transcriptional regulator
C6N15_RS22495	COG2197	response regulator
C6N15_RS22500	COG2233	PERMEase
C6N15_RS22510	COG0402	S-adenosylhomocysteine deaminase activity
C6N15_RS22515	COG0402	S-adenosylhomocysteine deaminase activity
C6N15_RS22525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C6N15_RS22535	COG0444	Belongs to the ABC transporter superfamily
C6N15_RS22540	COG4608	Belongs to the ABC transporter superfamily
C6N15_RS22545	COG3275	phosphorelay sensor kinase activity
C6N15_RS22550	COG3279	Response regulator of the LytR AlgR family
C6N15_RS22565	COG1983	PspC domain protein
C6N15_RS22570	COG1396	sequence-specific DNA binding
C6N15_RS22575	COG0697	spore germination
C6N15_RS22585	COG1959	2 iron, 2 sulfur cluster binding
C6N15_RS22590	COG1668	transmembrane transport
C6N15_RS22595	COG4152	abc transporter atp-binding protein
C6N15_RS22600	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C6N15_RS22610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C6N15_RS22615	COG1876	peptidase activity
C6N15_RS22620	COG0824	Thioesterase
C6N15_RS22625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C6N15_RS22630	COG1053	succinate dehydrogenase
C6N15_RS22635	COG2009	succinate dehydrogenase
C6N15_RS22640	COG1719	4-vinyl reductase, 4VR
C6N15_RS22650	COG3118	belongs to the thioredoxin family
C6N15_RS22655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C6N15_RS22660	COG2086	electron transfer activity
C6N15_RS22665	COG1024	Enoyl-CoA hydratase
C6N15_RS22670	COG1309	transcriptional regulator
C6N15_RS22675	COG0318	PFAM AMP-dependent synthetase and ligase
C6N15_RS22695	COG2318	DinB family
C6N15_RS22725	COG1131	(ABC) transporter
C6N15_RS22730	COG2205	protein histidine kinase activity
C6N15_RS22735	COG0745	RESPONSE REGULATOR receiver
C6N15_RS22745	COG4895	conserved protein (DUF2196)
C6N15_RS22750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C6N15_RS22765	COG4509	Sortase family
C6N15_RS22770	COG1120	ATPase activity
C6N15_RS22785	COG5386	Cell surface protein
C6N15_RS22795	COG5386	Cell surface protein
C6N15_RS22800	COG1114	Component of the transport system for branched-chain amino acids
C6N15_RS22805	COG1187	pseudouridine synthase activity
C6N15_RS22815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C6N15_RS22815	COG1796	DNA polymerase
C6N15_RS22820	COG1286	toxin biosynthetic process
C6N15_RS22865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C6N15_RS22875	COG1418	mRNA catabolic process
C6N15_RS22900	COG2814	Major facilitator Superfamily
C6N15_RS22905	COG1566	PFAM secretion protein HlyD family protein
C6N15_RS22910	COG1309	transcriptional regulator
C6N15_RS22915	COG1363	Peptidase, m42
C6N15_RS22940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C6N15_RS22950	COG1484	DNA-dependent DNA replication
C6N15_RS22955	COG3611	Membrane attachment protein
C6N15_RS22965	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C6N15_RS22970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6N15_RS22975	COG0237	dephospho-CoA kinase activity
C6N15_RS22980	COG1971	Probably functions as a manganese efflux pump
C6N15_RS22990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N15_RS22990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C6N15_RS22995	COG5002	protein histidine kinase activity
C6N15_RS23000	COG0745	RESPONSE REGULATOR receiver
C6N15_RS23020	COG0538	isocitrate dehydrogenase activity
C6N15_RS23025	COG0372	Belongs to the citrate synthase family
C6N15_RS23035	COG0628	permease
C6N15_RS23040	COG3030	protein affecting phage T7 exclusion by the F plasmid
C6N15_RS23065	COG1725	Transcriptional regulator
C6N15_RS23070	COG0281	malic enzyme
C6N15_RS23075	COG0587	DNA-directed DNA polymerase activity
C6N15_RS23090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C6N15_RS23110	COG4109	DRTGG domain
C6N15_RS23125	COG0006	proline dipeptidase activity
C6N15_RS23160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS23165	COG0662	Cupin 2, conserved barrel domain protein
C6N15_RS23175	COG1476	TRANSCRIPTIONal
C6N15_RS23190	COG1028	Short-chain dehydrogenase reductase Sdr
C6N15_RS23195	COG0589	response to stress
C6N15_RS23235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS23255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C6N15_RS23260	COG0827	DNA restriction-modification system
C6N15_RS23265	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C6N15_RS23270	COG3874	Sporulation protein YtfJ
C6N15_RS23285	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C6N15_RS23295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N15_RS23310	COG1104	cysteine desulfurase activity
C6N15_RS23320	COG0583	DNA-binding transcription factor activity
C6N15_RS23325	COG0697	spore germination
C6N15_RS23335	COG1956	GAF domain-containing protein
C6N15_RS23340	COG0626	cystathionine gamma-synthase activity
C6N15_RS23370	COG1595	DNA-templated transcription, initiation
C6N15_RS23380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C6N15_RS23385	COG0454	-acetyltransferase
C6N15_RS23390	COG0517	IMP dehydrogenase activity
C6N15_RS23395	COG0123	including yeast histone deacetylase and acetoin utilization protein
C6N15_RS23405	COG0745	RESPONSE REGULATOR receiver
C6N15_RS23415	COG0666	response to abiotic stimulus
C6N15_RS23450	COG1609	Transcriptional regulator
C6N15_RS23455	COG4851	CamS sex pheromone cAM373 precursor
C6N15_RS23460	COG3118	belongs to the thioredoxin family
C6N15_RS23470	COG2309	aminopeptidase activity
C6N15_RS23490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS23505	COG1674	ftsk spoiiie
C6N15_RS23515	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C6N15_RS23520	COG4848	Belongs to the UPF0354 family
C6N15_RS23525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6N15_RS23530	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C6N15_RS23535	COG1363	Peptidase, m42
C6N15_RS23545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS23560	COG0510	thiamine kinase activity
C6N15_RS23565	COG1523	belongs to the glycosyl hydrolase 13 family
C6N15_RS23580	COG1349	DNA-binding transcription factor activity
C6N15_RS23585	COG1187	pseudouridine synthase activity
C6N15_RS23590	COG2244	polysaccharide biosynthetic process
C6N15_RS23595	COG2081	HI0933 family
C6N15_RS23600	COG2814	Major facilitator Superfamily
C6N15_RS23610	COG3832	glyoxalase III activity
C6N15_RS23630	COG1329	Transcriptional regulator
C6N15_RS23640	COG4975	Glucose uptake
C6N15_RS23655	COG0314	molybdopterin synthase activity
C6N15_RS23660	COG1763	Mo-molybdopterin cofactor biosynthetic process
C6N15_RS23665	COG0303	'Molybdopterin
C6N15_RS23675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C6N15_RS23700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C6N15_RS23710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C6N15_RS23750	COG2814	Major facilitator Superfamily
C6N15_RS23755	COG0475	glutathione-regulated potassium exporter activity
C6N15_RS23760	COG0490	domain, Protein
C6N15_RS23765	COG0582	viral genome integration into host DNA
C6N15_RS23775	COG1136	(ABC) transporter
C6N15_RS23795	COG1242	4 iron, 4 sulfur cluster binding
C6N15_RS23800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C6N15_RS23805	COG1131	(ABC) transporter
C6N15_RS23815	COG1794	racemase activity, acting on amino acids and derivatives
C6N15_RS23835	COG2267	carboxylic ester hydrolase activity
C6N15_RS23840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C6N15_RS23845	COG0671	phosphoesterase, PA-phosphatase related
C6N15_RS23850	COG0438	transferase activity, transferring glycosyl groups
C6N15_RS23860	COG0521	Mo-molybdopterin cofactor biosynthetic process
C6N15_RS23915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C6N15_RS23920	COG5002	protein histidine kinase activity
C6N15_RS23925	COG4191	Histidine kinase
C6N15_RS23930	COG2267	carboxylic ester hydrolase activity
C6N15_RS23950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C6N15_RS23955	COG1116	anion transmembrane transporter activity
C6N15_RS23960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C6N15_RS23985	COG0494	nUDIX hydrolase
C6N15_RS24015	COG0288	reversible hydration of carbon dioxide
C6N15_RS24020	COG1271	oxidase subunit
C6N15_RS24025	COG1294	oxidase, subunit
C6N15_RS24045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS24070	COG1842	Phage shock protein A
C6N15_RS24100	COG5002	protein histidine kinase activity
C6N15_RS24105	COG0745	RESPONSE REGULATOR receiver
C6N15_RS24135	COG1597	lipid kinase activity
C6N15_RS24170	COG0586	Pfam SNARE associated Golgi protein
C6N15_RS24180	COG0577	efflux transmembrane transporter activity
C6N15_RS24185	COG1136	(ABC) transporter
C6N15_RS24190	COG3708	Transcriptional regulator
C6N15_RS24190	COG2207	Transcriptional regulator
C6N15_RS24195	COG0745	RESPONSE REGULATOR receiver
C6N15_RS24200	COG2205	protein histidine kinase activity
C6N15_RS24205	COG0577	efflux transmembrane transporter activity
C6N15_RS24215	COG0577	efflux transmembrane transporter activity
C6N15_RS24220	COG1136	(ABC) transporter
C6N15_RS24240	COG2188	Transcriptional regulator
C6N15_RS24260	COG3964	amidohydrolase
C6N15_RS24290	COG4948	Mandelate Racemase Muconate Lactonizing
C6N15_RS24300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C6N15_RS24305	COG0596	Alpha beta hydrolase
C6N15_RS24310	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C6N15_RS24315	COG1169	isochorismate synthase
C6N15_RS24320	COG1575	Belongs to the MenA family. Type 1 subfamily
C6N15_RS24325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C6N15_RS24345	COG0058	SHG alpha-glucan phosphorylase activity
C6N15_RS24350	COG0297	glycogen (starch) synthase activity
C6N15_RS24355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C6N15_RS24475	COG0544	peptidyl-prolyl cis-trans isomerase activity
C6N15_RS24510	COG1285	pathogenesis
C6N15_RS24515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N15_RS24525	COG0166	Belongs to the GPI family
C6N15_RS24530	COG2155	Conserved Protein
C6N15_RS24535	COG1098	S1 RNA binding domain
C6N15_RS24540	COG0436	Aminotransferase
C6N15_RS24545	COG1522	sequence-specific DNA binding
C6N15_RS24550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C6N15_RS24555	COG2267	carboxylic ester hydrolase activity
C6N15_RS24565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C6N15_RS24585	COG5018	Exonuclease
C6N15_RS24590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6N15_RS24610	COG2050	protein possibly involved in aromatic compounds catabolism
C6N15_RS24620	COG1268	BioY protein
C6N15_RS24630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C6N15_RS24635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C6N15_RS24650	COG3584	3D domain protein
C6N15_RS24665	COG1252	NADH dehydrogenase
C6N15_RS24680	COG3708	Transcriptional regulator
C6N15_RS24695	COG1683	Conserved Protein
C6N15_RS24715	COG0316	Belongs to the HesB IscA family
C6N15_RS24730	COG1252	NADH dehydrogenase
C6N15_RS24745	COG0390	transport system, permease component
C6N15_RS24750	COG2824	Alkylphosphonate utilization operon protein PhnA
C6N15_RS24790	COG4837	Protein of unknown function (DUF1462)
C6N15_RS24795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C6N15_RS24805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C6N15_RS24810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C6N15_RS24820	COG2249	NAD(P)H dehydrogenase (quinone) activity
C6N15_RS24825	COG0647	UMP catabolic process
C6N15_RS24835	COG2445	Protein of unknown function DUF86
C6N15_RS24840	COG1494	fructose-1,6-bisphosphatase
C6N15_RS24855	COG4470	Protein conserved in bacteria
C6N15_RS24865	COG0789	Transcriptional regulator
C6N15_RS24870	COG4377	Putative membrane peptidase family (DUF2324)
C6N15_RS24895	COG0739	heme binding
C6N15_RS24905	COG3377	Domain of unknown function (DUF1805)
C6N15_RS24910	COG0737	Belongs to the 5'-nucleotidase family
C6N15_RS24915	COG1695	Transcriptional regulator
C6N15_RS24925	COG0719	Fe-S assembly protein
C6N15_RS24930	COG0822	iron-sulfur transferase activity
C6N15_RS24935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C6N15_RS24940	COG0719	Fe-S assembly protein
C6N15_RS24945	COG0396	ATPase activity
C6N15_RS24950	COG1464	Belongs to the NlpA lipoprotein family
C6N15_RS24955	COG1464	Belongs to the NlpA lipoprotein family
C6N15_RS24960	COG2011	ABC-type metal ion transport system permease component
C6N15_RS24965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C6N15_RS24975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C6N15_RS24980	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C6N15_RS24990	COG1393	Belongs to the ArsC family
C6N15_RS25035	COG0039	L-malate dehydrogenase activity
C6N15_RS25055	COG1309	transcriptional regulator
C6N15_RS25060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C6N15_RS25065	COG1960	acyl-CoA dehydrogenase activity
C6N15_RS25070	COG0183	Belongs to the thiolase family
C6N15_RS25075	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N15_RS25075	COG1024	Enoyl-CoA hydratase
C6N15_RS25085	COG1686	Belongs to the peptidase S11 family
C6N15_RS25100	COG0011	TIGRFAM Protein of
C6N15_RS25105	COG0840	transmembrane signaling receptor activity
C6N15_RS25125	COG2814	Major facilitator Superfamily
C6N15_RS25130	COG0531	amino acid
C6N15_RS25140	COG0706	membrane insertase activity
C6N15_RS25150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C6N15_RS25185	COG0586	Pfam SNARE associated Golgi protein
C6N15_RS25195	COG1376	ErfK ybiS ycfS ynhG family protein
C6N15_RS25200	COG0745	RESPONSE REGULATOR receiver
C6N15_RS25205	COG5002	protein histidine kinase activity
C6N15_RS25230	COG2151	metal-sulfur cluster biosynthetic enzyme
C6N15_RS25235	COG3227	Zinc metalloprotease (Elastase)
C6N15_RS25240	COG1741	Belongs to the pirin family
C6N15_RS25255	COG0475	glutathione-regulated potassium exporter activity
C6N15_RS25260	COG0490	domain, Protein
C6N15_RS25265	COG1115	amino acid carrier protein
C6N15_RS25270	COG0783	Belongs to the Dps family
C6N15_RS25285	COG1611	Belongs to the LOG family
C6N15_RS25305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS25310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS25315	COG1115	amino acid carrier protein
C6N15_RS25320	COG1115	amino acid carrier protein
C6N15_RS25325	COG2910	NAD(P)H-binding
C6N15_RS25340	COG0656	L-ascorbic acid biosynthetic process
C6N15_RS25345	COG2814	Major facilitator Superfamily
C6N15_RS25350	COG1733	regulation of RNA biosynthetic process
C6N15_RS25360	COG1252	NADH dehydrogenase
C6N15_RS25365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C6N15_RS25370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C6N15_RS25380	COG3290	protein histidine kinase activity
C6N15_RS25380	COG0840	transmembrane signaling receptor activity
C6N15_RS25390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6N15_RS25395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C6N15_RS25410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C6N15_RS25465	COG0557	exoribonuclease II activity
C6N15_RS25470	COG1647	Serine aminopeptidase, S33
C6N15_RS25475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C6N15_RS25480	COG1346	cytolysis
C6N15_RS25580	COG4695	Portal protein
C6N15_RS25605	COG4974	Belongs to the 'phage' integrase family
C6N15_RS25615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C6N15_RS25620	COG0149	triose-phosphate isomerase activity
C6N15_RS25630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C6N15_RS25645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C6N15_RS25670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C6N15_RS25685	COG2323	membrane
C6N15_RS25690	COG0740	serine-type endopeptidase activity
C6N15_RS25695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C6N15_RS25705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C6N15_RS25715	COG1051	belongs to the nudix hydrolase family
C6N15_RS25725	COG0492	ferredoxin-NADP+ reductase activity
C6N15_RS25730	COG0457	Tetratricopeptide repeat
C6N15_RS25735	COG0110	maltose O-acetyltransferase activity
C6N15_RS25755	COG1950	PFAM Membrane protein of
C6N15_RS25765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C6N15_RS25770	COG0556	nucleotide-excision repair
C6N15_RS25790	COG0789	Transcriptional regulator
C6N15_RS25815	COG2855	membrane
C6N15_RS25820	COG0583	DNA-binding transcription factor activity
C6N15_RS25830	COG0655	NAD(P)H dehydrogenase (quinone) activity
C6N15_RS25835	COG0488	(ABC) transporter
C6N15_RS25845	COG1132	(ABC) transporter
C6N15_RS25850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N15_RS25855	COG3409	Peptidoglycan-binding domain 1 protein
C6N15_RS25855	COG0793	Belongs to the peptidase S41A family
C6N15_RS25860	COG2177	Part of the ABC transporter FtsEX involved in
C6N15_RS25865	COG2884	Cell division ATP-binding protein ftsE
C6N15_RS25880	COG0653	protein targeting
C6N15_RS25885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C6N15_RS25890	COG1278	Cold shock
C6N15_RS25895	COG1040	competence protein
C6N15_RS25900	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C6N15_RS25905	COG1388	LysM domain
C6N15_RS25905	COG0791	NLP P60 protein
C6N15_RS25910	COG1733	regulation of RNA biosynthetic process
C6N15_RS25915	COG1307	EDD domain protein, DegV family
C6N15_RS25920	COG1739	Uncharacterized protein family UPF0029
C6N15_RS25925	COG1316	TRANSCRIPTIONal
C6N15_RS25930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N15_RS25935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C6N15_RS25940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C6N15_RS25950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C6N15_RS25950	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C6N15_RS25965	COG3394	polysaccharide catabolic process
C6N15_RS25970	COG1486	melibiose metabolic process
C6N15_RS25975	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N15_RS25980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N15_RS25990	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C6N15_RS25995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C6N15_RS26000	COG1447	Phosphotransferase system cellobiose-specific component IIA
C6N15_RS26010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C6N15_RS26015	COG1301	dicarboxylic acid transport
C6N15_RS26025	COG0346	lactoylglutathione lyase activity
C6N15_RS26030	COG1511	domain protein
C6N15_RS26035	COG0583	DNA-binding transcription factor activity
C6N15_RS26040	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C6N15_RS26055	COG1271	oxidase subunit
C6N15_RS26060	COG1294	oxidase, subunit
C6N15_RS26065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C6N15_RS26085	COG2389	metal-binding protein
C6N15_RS26095	COG1368	sulfuric ester hydrolase activity
C6N15_RS26110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C6N15_RS26120	COG1215	transferase activity, transferring glycosyl groups
C6N15_RS26125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N15_RS26130	COG1388	LysM domain
C6N15_RS26130	COG3584	3D domain protein
C6N15_RS26155	COG4715	Zinc finger, swim domain protein
C6N15_RS26160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C6N15_RS26200	COG0577	efflux transmembrane transporter activity
C6N15_RS26205	COG1136	(ABC) transporter
C6N15_RS26240	COG5002	protein histidine kinase activity
C6N15_RS26245	COG0745	RESPONSE REGULATOR receiver
C6N15_RS26250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6N15_RS26265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C6N15_RS26270	COG1134	teichoic acid transport
C6N15_RS26275	COG1682	transport, permease protein
C6N15_RS26280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C6N15_RS26325	COG1609	Transcriptional regulator
C6N15_RS26340	COG0739	heme binding
C6N15_RS26360	COG2385	sporulation resulting in formation of a cellular spore
C6N15_RS26375	COG4836	Membrane
C6N15_RS26380	COG1007	ATP synthesis coupled electron transport
C6N15_RS26385	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N15_RS26390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C6N15_RS26400	COG0839	Belongs to the complex I subunit 6 family
C6N15_RS26415	COG0649	NAD binding
C6N15_RS26420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C6N15_RS26435	COG5001	Diguanylate cyclase
C6N15_RS26435	COG3300	MHYT domain
C6N15_RS26485	COG0356	it plays a direct role in the translocation of protons across the membrane
C6N15_RS26520	COG0698	ribose 5-phosphate isomerase
C6N15_RS26530	COG2190	(PTS) system
C6N15_RS26535	COG2259	Doxx family
C6N15_RS26540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C6N15_RS26555	COG0009	L-threonylcarbamoyladenylate synthase
C6N15_RS26570	COG2890	protein-(glutamine-N5) methyltransferase activity
C6N15_RS26590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C6N15_RS26595	COG1494	fructose-1,6-bisphosphatase
C6N15_RS26615	COG4821	SIS domain
C6N15_RS26625	COG3343	RNA polymerase activity
C6N15_RS26635	COG1960	acyl-CoA dehydrogenase activity
C6N15_RS26640	COG1960	acyl-CoA dehydrogenase activity
C6N15_RS26645	COG1250	3-hydroxyacyl-CoA dehydrogenase
C6N15_RS26650	COG0183	Belongs to the thiolase family
C6N15_RS26655	COG2181	nitrate reductase activity
C6N15_RS26655	COG0247	lactate metabolic process
C6N15_RS26660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C6N15_RS26670	COG5001	Diguanylate cyclase
C6N15_RS26670	COG3300	MHYT domain
C6N15_RS26690	COG2197	response regulator
C6N15_RS26695	COG4585	Histidine kinase
C6N15_RS26700	COG0842	Transport permease protein
C6N15_RS26705	COG1131	(ABC) transporter
C6N15_RS26710	COG0024	Methionine aminopeptidase
C6N15_RS26720	COG2234	aminopeptidase activity
C6N15_RS26740	COG1595	DNA-templated transcription, initiation
C6N15_RS26745	COG0018	arginyl-trna synthetase
C6N15_RS26750	COG4506	Protein conserved in bacteria
C6N15_RS26755	COG1619	proteins homologs of microcin C7 resistance protein MccF
C6N15_RS26770	COG0010	Belongs to the arginase family
C6N15_RS26780	COG2814	Major facilitator Superfamily
C6N15_RS26785	COG0789	Transcriptional regulator
C6N15_RS26790	COG0584	glycerophosphoryl diester phosphodiesterase
C6N15_RS26795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C6N15_RS26805	COG1994	Peptidase M50
C6N15_RS26815	COG1078	dGTPase activity
C6N15_RS26820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C6N15_RS26825	COG1120	ATPase activity
C6N15_RS26830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C6N15_RS26855	COG0095	Lipoate-protein ligase
C6N15_RS26860	COG0280	phosphate acetyltransferase
C6N15_RS26875	COG3773	Cell wall hydrolase
C6N15_RS26885	COG2363	Small membrane protein
C6N15_RS26895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C6N15_RS26900	COG2233	PERMEase
C6N15_RS26905	COG0561	phosphatase activity
C6N15_RS26910	COG2814	Major facilitator Superfamily
C6N15_RS26920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C6N15_RS26925	COG1131	(ABC) transporter
C6N15_RS26930	COG2755	lipolytic protein G-D-S-L family
C6N15_RS26935	COG1609	Transcriptional regulator
C6N15_RS26945	COG0460	homoserine dehydrogenase
C6N15_RS26955	COG2873	o-acetylhomoserine
C6N15_RS26965	COG1011	Hydrolase
C6N15_RS26970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C6N15_RS26980	COG2197	response regulator
C6N15_RS26990	COG0351	phosphomethylpyrimidine kinase
C6N15_RS26995	COG3706	GGDEF domain
C6N15_RS27000	COG2879	small protein
C6N15_RS27005	COG1966	Carbon starvation protein
C6N15_RS27010	COG3279	Response regulator of the LytR AlgR family
C6N15_RS27015	COG0477	Major facilitator Superfamily
C6N15_RS27040	COG0840	transmembrane signaling receptor activity
C6N15_RS27050	COG1607	acyl-coa hydrolase
C6N15_RS27065	COG0488	(ABC) transporter
C6N15_RS27085	COG0463	Glycosyl transferase, family 2
C6N15_RS27090	COG1309	transcriptional regulator
C6N15_RS27095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C6N15_RS27100	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6N15_RS27100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C6N15_RS27105	COG0628	permease
C6N15_RS27120	COG3279	Response regulator of the LytR AlgR family
C6N15_RS27125	COG3275	phosphorelay sensor kinase activity
C6N15_RS27130	COG2814	Major facilitator Superfamily
C6N15_RS27135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C6N15_RS27140	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C6N15_RS27145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C6N15_RS27165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C6N15_RS27170	COG1272	protein, Hemolysin III
C6N15_RS27190	COG0516	GMP reductase activity
C6N15_RS27195	COG1164	Oligoendopeptidase f
C6N15_RS27215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C6N15_RS27220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C6N15_RS27225	COG4853	Protein conserved in bacteria
C6N15_RS27230	COG4863	YycH protein
C6N15_RS27235	COG5002	protein histidine kinase activity
C6N15_RS27240	COG0745	RESPONSE REGULATOR receiver
C6N15_RS27270	COG0305	Participates in initiation and elongation during chromosome replication
C6N15_RS27280	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C6N15_RS27285	COG4241	membrane
C6N15_RS27295	COG0629	single-stranded DNA binding
C6N15_RS27305	COG0012	GTP binding
C6N15_RS27310	COG4481	Protein conserved in bacteria
C6N15_RS27315	COG0668	transmembrane transport
C6N15_RS27325	COG1475	DNA binding
C6N15_RS27330	COG1192	Involved in chromosome partitioning
C6N15_RS27355	COG1847	R3H domain protein
C6N15_RS27360	COG0706	membrane insertase activity
C6N15_RS27370	COG0230	Belongs to the bacterial ribosomal protein bL34 family