locus-tag	class	description
AW166_RS00165	COG1774	PSP1 C-terminal conserved region
AW166_RS00275	COG3956	TIGRFAM MazG family protein
AW166_RS00350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW166_RS00455	COG1045	serine acetyltransferase
AW166_RS00690	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW166_RS00760	COG2610	gluconate transmembrane transporter activity
AW166_RS00765	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW166_RS00825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_RS01335	COG0592	DNA-directed DNA polymerase activity
AW166_RS01340	COG2501	S4 domain
AW166_RS01350	COG0187	DNA topoisomerase II activity
AW166_RS01355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW166_RS01390	COG0516	GMP reductase activity
AW166_RS01390	COG0517	IMP dehydrogenase activity
AW166_RS01395	COG1686	Belongs to the peptidase S11 family
AW166_RS01425	COG1428	Deoxynucleoside kinase
AW166_RS01430	COG1428	Deoxynucleoside kinase
AW166_RS01435	COG1335	isochorismatase
AW166_RS01445	COG0590	tRNA wobble adenosine to inosine editing
AW166_RS01455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW166_RS01510	COG1982	Orn Lys Arg decarboxylase major
AW166_RS01520	COG0470	DNA polymerase III
AW166_RS01525	COG1774	PSP1 C-terminal conserved region
AW166_RS01535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW166_RS01545	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW166_RS01550	COG2002	toxin-antitoxin pair type II binding
AW166_RS01555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_RS01555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_RS01560	COG0084	hydrolase, TatD family'
AW166_RS01565	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW166_RS01580	COG4466	Protein conserved in bacteria
AW166_RS01595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW166_RS01600	COG0251	oxidation-reduction process
AW166_RS01630	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW166_RS01635	COG2002	toxin-antitoxin pair type II binding
AW166_RS01640	COG2244	polysaccharide biosynthetic process
AW166_RS01645	COG3956	TIGRFAM MazG family protein
AW166_RS01650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW166_RS01670	COG1098	S1 RNA binding domain
AW166_RS01685	COG2208	phosphoserine phosphatase activity
AW166_RS01690	COG0037	tRNA processing
AW166_RS01695	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AW166_RS01700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW166_RS01715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW166_RS01720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW166_RS01725	COG0512	Glutamine amidotransferase of anthranilate synthase
AW166_RS01730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_RS01735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW166_RS01740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW166_RS01745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW166_RS01750	COG1396	sequence-specific DNA binding
AW166_RS01755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW166_RS01785	COG3880	PFAM UvrB UvrC protein
AW166_RS01795	COG0542	response to heat
AW166_RS01800	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW166_RS01810	COG4956	integral membrane protein (PIN domain superfamily)
AW166_RS01830	COG1045	serine acetyltransferase
AW166_RS01845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW166_RS01850	COG3688	RNA-binding protein containing a PIN domain
AW166_RS01865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW166_RS01870	COG0250	Participates in transcription elongation, termination and antitermination
AW166_RS01875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AW166_RS01895	COG2813	Specifically methylates the guanine in position
AW166_RS01905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AW166_RS01910	COG1358	cellular component organization or biogenesis
AW166_RS01980	COG0255	Belongs to the universal ribosomal protein uL29 family
AW166_RS02040	COG0201	protein transport
AW166_RS02050	COG0024	Methionine aminopeptidase
AW166_RS02060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW166_RS02095	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW166_RS02120	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_RS02125	COG0489	protein tyrosine kinase activity
AW166_RS02135	COG2194	sulfuric ester hydrolase activity
AW166_RS02140	COG0726	polysaccharide deacetylase
AW166_RS02225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW166_RS02230	COG4856	YbbR-like protein
AW166_RS02245	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW166_RS02250	COG0596	Alpha beta hydrolase
AW166_RS02270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW166_RS02275	COG1506	peptidase
AW166_RS02275	COG4946	Tricorn protease homolog
AW166_RS02275	COG0823	Involved in the tonB-independent uptake of proteins
AW166_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS02315	COG2011	ABC-type metal ion transport system permease component
AW166_RS02320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_RS02325	COG1464	Belongs to the NlpA lipoprotein family
AW166_RS02330	COG0604	alcohol dehydrogenase
AW166_RS02340	COG0277	FAD linked oxidase domain protein
AW166_RS02345	COG2271	Major facilitator Superfamily
AW166_RS02355	COG2814	Major facilitator Superfamily
AW166_RS02370	COG0601	transmembrane transport
AW166_RS02375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_RS02380	COG0444	Belongs to the ABC transporter superfamily
AW166_RS02385	COG4608	Belongs to the ABC transporter superfamily
AW166_RS02390	COG4166	transmembrane transport
AW166_RS02400	COG2207	Transcriptional regulator
AW166_RS02415	COG4166	transmembrane transport
AW166_RS02420	COG4166	transmembrane transport
AW166_RS02425	COG0656	L-ascorbic acid biosynthetic process
AW166_RS02430	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_RS02450	COG4149	molybdate abc transporter
AW166_RS02455	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW166_RS02460	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW166_RS02465	COG1910	domain protein
AW166_RS02480	COG0583	DNA-binding transcription factor activity
AW166_RS02485	COG0697	spore germination
AW166_RS02495	COG0204	Acyl-transferase
AW166_RS02505	COG1609	Transcriptional regulator
AW166_RS02515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS02530	COG0084	hydrolase, TatD family'
AW166_RS02535	COG5298	Protein conserved in bacteria
AW166_RS02560	COG0488	(ABC) transporter
AW166_RS02575	COG0747	negative chemotaxis
AW166_RS02580	COG0601	transmembrane transport
AW166_RS02585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_RS02590	COG0444	Belongs to the ABC transporter superfamily
AW166_RS02595	COG4608	Belongs to the ABC transporter superfamily
AW166_RS02620	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AW166_RS02625	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW166_RS02635	COG2814	Major facilitator Superfamily
AW166_RS02650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW166_RS02660	COG4294	response to UV
AW166_RS02665	COG0457	Tetratricopeptide repeat
AW166_RS02665	COG0705	Rhomboid family
AW166_RS02675	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW166_RS02680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW166_RS02685	COG0864	Transcriptional regulator
AW166_RS02690	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW166_RS02695	COG2183	response to ionizing radiation
AW166_RS02790	COG0802	atpase or kinase
AW166_RS02795	COG1214	PFAM Peptidase M22, glycoprotease
AW166_RS02800	COG0456	acetyltransferase
AW166_RS02810	COG0488	(ABC) transporter
AW166_RS02825	COG1266	CAAX protease self-immunity
AW166_RS02845	COG2252	PERMEase
AW166_RS02855	COG5002	protein histidine kinase activity
AW166_RS02885	COG2226	methyltransferase
AW166_RS02925	COG1968	undecaprenyl-diphosphatase activity
AW166_RS02940	COG2205	protein histidine kinase activity
AW166_RS02945	COG0745	RESPONSE REGULATOR receiver
AW166_RS02965	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW166_RS02970	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW166_RS02975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW166_RS02985	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW166_RS03000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW166_RS03010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW166_RS03020	COG0151	Belongs to the GarS family
AW166_RS03045	COG0210	DNA helicase
AW166_RS03055	COG4851	CamS sex pheromone cAM373 precursor
AW166_RS03075	COG1335	isochorismatase
AW166_RS03080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_RS03085	COG2011	ABC-type metal ion transport system permease component
AW166_RS03090	COG1464	Belongs to the NlpA lipoprotein family
AW166_RS03110	COG1846	Transcriptional regulator
AW166_RS03135	COG1597	lipid kinase activity
AW166_RS03140	COG0546	phosphoglycolate phosphatase activity
AW166_RS03145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW166_RS03155	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS03160	COG2076	Multidrug Resistance protein
AW166_RS03165	COG2309	aminopeptidase activity
AW166_RS03180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS03185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW166_RS03190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW166_RS03200	COG4807	Protein conserved in bacteria
AW166_RS03225	COG1757	Na H antiporter
AW166_RS03230	COG1473	amidohydrolase
AW166_RS03245	COG0450	alkyl hydroperoxide reductase
AW166_RS03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS03275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS03295	COG0166	Belongs to the GPI family
AW166_RS03330	COG5002	protein histidine kinase activity
AW166_RS03350	COG3541	Predicted nucleotidyltransferase
AW166_RS03355	COG2814	Major facilitator Superfamily
AW166_RS03360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_RS03360	COG0723	plastoquinol--plastocyanin reductase activity
AW166_RS03370	COG0765	amino acid transport
AW166_RS03375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_RS03390	COG0840	transmembrane signaling receptor activity
AW166_RS03395	COG0840	transmembrane signaling receptor activity
AW166_RS03400	COG0366	Alpha amylase catalytic
AW166_RS03405	COG1263	PTS System
AW166_RS03405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_RS03405	COG2190	(PTS) system
AW166_RS03435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW166_RS03450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_RS03460	COG1116	anion transmembrane transporter activity
AW166_RS03465	COG0488	(ABC) transporter
AW166_RS03510	COG2270	Major facilitator Superfamily
AW166_RS03525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW166_RS03540	COG2310	stress, protein
AW166_RS03545	COG2310	stress, protein
AW166_RS03550	COG2310	stress, protein
AW166_RS03555	COG0861	Integral membrane protein TerC family
AW166_RS03565	COG3853	Toxic anion resistance protein (TelA)
AW166_RS03580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW166_RS03590	COG1295	ribonuclease BN
AW166_RS03595	COG2217	Heavy metal translocating P-type atpase
AW166_RS03600	COG0697	spore germination
AW166_RS03620	COG0586	Pfam SNARE associated Golgi protein
AW166_RS03635	COG3871	stress protein (general stress protein 26)
AW166_RS03640	COG0387	Pfam Sodium calcium exchanger
AW166_RS03650	COG0535	radical SAM domain protein
AW166_RS03675	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW166_RS03680	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW166_RS03685	COG0582	viral genome integration into host DNA
AW166_RS03690	COG1396	sequence-specific DNA binding
AW166_RS03705	COG1396	sequence-specific DNA binding
AW166_RS03740	COG1484	DNA-dependent DNA replication
AW166_RS03835	COG0582	viral genome integration into host DNA
AW166_RS03840	COG0582	viral genome integration into host DNA
AW166_RS03965	COG0101	tRNA pseudouridine synthase activity
AW166_RS03975	COG3829	transcription factor binding
AW166_RS03985	COG0833	amino acid
AW166_RS03990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_RS04025	COG1263	PTS System
AW166_RS04025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_RS04030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_RS04045	COG0463	Glycosyl transferase, family 2
AW166_RS04060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW166_RS04060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW166_RS04080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW166_RS04100	COG1228	amidohydrolase
AW166_RS04105	COG1090	epimerase
AW166_RS04135	COG1988	membrane-bound metal-dependent
AW166_RS04140	COG1194	a g-specific adenine glycosylase
AW166_RS04165	COG1132	(ABC) transporter
AW166_RS04170	COG4129	membrane
AW166_RS04175	COG0070	glutamate synthase
AW166_RS04175	COG0069	glutamate synthase activity
AW166_RS04175	COG0067	glutamate synthase
AW166_RS04185	COG4555	ABC transporter
AW166_RS04205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW166_RS04210	COG0735	belongs to the Fur family
AW166_RS04325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AW166_RS04330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AW166_RS04340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW166_RS04350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW166_RS04365	COG2766	serine protein kinase
AW166_RS04390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW166_RS04400	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW166_RS04405	COG2268	Band 7 protein
AW166_RS04415	COG3290	protein histidine kinase activity
AW166_RS04425	COG2851	Citrate transporter
AW166_RS04445	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW166_RS04450	COG3842	ATPase activity
AW166_RS04455	COG1175	transmembrane transport
AW166_RS04460	COG0395	ABC-type sugar transport system, permease component
AW166_RS04470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW166_RS04475	COG0745	RESPONSE REGULATOR receiver
AW166_RS04480	COG5002	protein histidine kinase activity
AW166_RS04490	COG4990	cell redox homeostasis
AW166_RS04500	COG3290	protein histidine kinase activity
AW166_RS04505	COG4565	transcriptional regulatory protein
AW166_RS04510	COG3493	citrate carrier protein
AW166_RS04515	COG0281	malic enzyme
AW166_RS04530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS04540	COG5002	protein histidine kinase activity
AW166_RS04545	COG0745	RESPONSE REGULATOR receiver
AW166_RS04555	COG0456	acetyltransferase
AW166_RS04555	COG0454	-acetyltransferase
AW166_RS04560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW166_RS04565	COG3383	formate dehydrogenase (NAD+) activity
AW166_RS04570	COG2427	Protein of unknown function (DUF1641)
AW166_RS04585	COG0531	amino acid
AW166_RS04590	COG0640	Transcriptional regulator
AW166_RS04595	COG2217	Heavy metal translocating P-type atpase
AW166_RS04600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW166_RS04610	COG3227	Zinc metalloprotease (Elastase)
AW166_RS04630	COG2720	vancomycin resistance protein
AW166_RS04635	COG1316	TRANSCRIPTIONal
AW166_RS04640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS04645	COG0346	lactoylglutathione lyase activity
AW166_RS04650	COG1253	flavin adenine dinucleotide binding
AW166_RS04655	COG1027	Aspartate ammonia-lyase
AW166_RS04660	COG1620	l-lactate permease
AW166_RS04675	COG3104	oligopeptide transport
AW166_RS04680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS04685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS04690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS04700	COG2226	methyltransferase
AW166_RS04705	COG0156	8-amino-7-oxononanoate synthase activity
AW166_RS04710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW166_RS04720	COG4548	von Willebrand factor, type A
AW166_RS04725	COG0714	Associated with various cellular activities
AW166_RS04730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_RS04750	COG0531	amino acid
AW166_RS04755	COG2188	Transcriptional regulator
AW166_RS04760	COG1263	PTS System
AW166_RS04760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_RS04765	COG0366	Alpha amylase catalytic
AW166_RS04780	COG0697	spore germination
AW166_RS04790	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW166_RS04795	COG1115	amino acid carrier protein
AW166_RS04800	COG1126	abc transporter atp-binding protein
AW166_RS04805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_RS04810	COG0765	amino acid transport
AW166_RS04815	COG0765	amino acid transport
AW166_RS04820	COG0833	amino acid
AW166_RS04845	COG2378	regulation of single-species biofilm formation
AW166_RS04850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW166_RS04855	COG5002	protein histidine kinase activity
AW166_RS04870	COG0659	secondary active sulfate transmembrane transporter activity
AW166_RS04885	COG0747	negative chemotaxis
AW166_RS04895	COG0601	transmembrane transport
AW166_RS04900	COG4608	Belongs to the ABC transporter superfamily
AW166_RS04910	COG2271	Major facilitator Superfamily
AW166_RS04915	COG1846	Transcriptional regulator
AW166_RS04920	COG0477	Major facilitator Superfamily
AW166_RS04925	COG0477	Major facilitator Superfamily
AW166_RS04930	COG1609	Transcriptional regulator
AW166_RS04935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW166_RS04950	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW166_RS04955	COG1879	ABC-type sugar transport system periplasmic component
AW166_RS04980	COG1063	alcohol dehydrogenase
AW166_RS04995	COG3568	Endonuclease Exonuclease Phosphatase
AW166_RS05020	COG1968	undecaprenyl-diphosphatase activity
AW166_RS05025	COG0840	transmembrane signaling receptor activity
AW166_RS05030	COG1388	LysM domain
AW166_RS05030	COG3584	3D domain protein
AW166_RS05035	COG1476	TRANSCRIPTIONal
AW166_RS05050	COG3104	oligopeptide transport
AW166_RS05055	COG1114	Component of the transport system for branched-chain amino acids
AW166_RS05070	COG1113	amino acid transport
AW166_RS05075	COG2252	PERMEase
AW166_RS05100	COG0475	glutathione-regulated potassium exporter activity
AW166_RS05100	COG0569	domain protein
AW166_RS05115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW166_RS05120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW166_RS05125	COG0833	amino acid
AW166_RS05130	COG4990	cell redox homeostasis
AW166_RS05145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_RS05150	COG0697	spore germination
AW166_RS05155	COG0531	amino acid
AW166_RS05170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW166_RS05175	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW166_RS05180	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW166_RS05180	COG1918	ferrous iron import across plasma membrane
AW166_RS05185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW166_RS05190	COG0573	inorganic phosphate transmembrane transporter activity
AW166_RS05195	COG0581	inorganic phosphate transmembrane transporter activity
AW166_RS05205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW166_RS05320	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW166_RS05345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW166_RS05350	COG1116	anion transmembrane transporter activity
AW166_RS05355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_RS05360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW166_RS05365	COG0352	thiamine-phosphate diphosphorylase activity
AW166_RS05370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_RS05375	COG2104	thiamine diphosphate biosynthetic process
AW166_RS05385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_RS05390	COG0351	phosphomethylpyrimidine kinase
AW166_RS05430	COG2205	protein histidine kinase activity
AW166_RS05435	COG2814	Major facilitator Superfamily
AW166_RS05440	COG1846	Transcriptional regulator
AW166_RS05455	COG2252	PERMEase
AW166_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS05475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW166_RS05480	COG1621	beta-fructofuranosidase activity
AW166_RS05485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_RS05485	COG1263	PTS System
AW166_RS05490	COG1609	Transcriptional regulator
AW166_RS05500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_RS05505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW166_RS05545	COG0778	Nitroreductase
AW166_RS05550	COG2719	SpoVR family
AW166_RS05575	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW166_RS05580	COG1937	Protein conserved in bacteria
AW166_RS05585	COG0425	Belongs to the sulfur carrier protein TusA family
AW166_RS05585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_RS05590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS05590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_RS05595	COG0425	Belongs to the sulfur carrier protein TusA family
AW166_RS05600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_RS05610	COG2210	Belongs to the sulfur carrier protein TusA family
AW166_RS05615	COG0730	response to heat
AW166_RS05625	COG1316	TRANSCRIPTIONal
AW166_RS05630	COG0604	alcohol dehydrogenase
AW166_RS05635	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW166_RS05650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW166_RS05650	COG3711	transcriptional antiterminator
AW166_RS05655	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW166_RS05660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW166_RS05680	COG1388	LysM domain
AW166_RS05680	COG3584	3D domain protein
AW166_RS05685	COG0577	efflux transmembrane transporter activity
AW166_RS05690	COG1136	(ABC) transporter
AW166_RS05700	COG5522	Integral membrane protein (intg_mem_TP0381)
AW166_RS05715	COG1114	Component of the transport system for branched-chain amino acids
AW166_RS05720	COG3546	catalase activity
AW166_RS05755	COG0586	Pfam SNARE associated Golgi protein
AW166_RS05790	COG0531	amino acid
AW166_RS05795	COG0475	glutathione-regulated potassium exporter activity
AW166_RS05805	COG1737	Transcriptional regulator
AW166_RS05815	COG1263	PTS System
AW166_RS05815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_RS05825	COG2259	Doxx family
AW166_RS05840	COG0697	spore germination
AW166_RS05845	COG1522	sequence-specific DNA binding
AW166_RS05860	COG2076	Multidrug Resistance protein
AW166_RS05865	COG1309	transcriptional regulator
AW166_RS05870	COG2814	Major facilitator Superfamily
AW166_RS05875	COG1733	regulation of RNA biosynthetic process
AW166_RS05885	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW166_RS05890	COG4533	DNA binding
AW166_RS05895	COG2211	Major facilitator Superfamily
AW166_RS05905	COG0693	protein deglycase activity
AW166_RS05910	COG0693	protein deglycase activity
AW166_RS05910	COG0753	catalase activity
AW166_RS05920	COG0531	amino acid
AW166_RS05925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW166_RS05935	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS05945	COG1132	(ABC) transporter
AW166_RS05955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_RS05960	COG0765	amino acid transport
AW166_RS05965	COG1126	abc transporter atp-binding protein
AW166_RS05980	COG0189	ligase activity
AW166_RS06010	COG0028	Belongs to the TPP enzyme family
AW166_RS06015	COG3527	Alpha-acetolactate decarboxylase
AW166_RS06030	COG0561	phosphatase activity
AW166_RS06045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW166_RS06060	COG0659	secondary active sulfate transmembrane transporter activity
AW166_RS06080	COG0653	protein targeting
AW166_RS06085	COG2244	polysaccharide biosynthetic process
AW166_RS06095	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_RS06100	COG4196	transglutaminase domain protein
AW166_RS06115	COG1696	Membrane protein involved in D-alanine export
AW166_RS06130	COG1024	Enoyl-CoA hydratase
AW166_RS06150	COG1363	Peptidase, m42
AW166_RS06170	COG3938	Belongs to the proline racemase family
AW166_RS06210	COG0601	transmembrane transport
AW166_RS06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_RS06225	COG4608	Belongs to the ABC transporter superfamily
AW166_RS06255	COG0477	Major facilitator Superfamily
AW166_RS06260	COG3290	protein histidine kinase activity
AW166_RS06265	COG4565	transcriptional regulatory protein
AW166_RS06270	COG3181	Tripartite tricarboxylate transporter family receptor
AW166_RS06300	COG0789	Transcriptional regulator
AW166_RS06300	COG4978	Transcriptional regulator
AW166_RS06315	COG0305	Participates in initiation and elongation during chromosome replication
AW166_RS06355	COG0477	Major facilitator Superfamily
AW166_RS06405	COG3320	Male sterility
AW166_RS06405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW166_RS06410	COG1309	transcriptional regulator
AW166_RS06430	COG1183	phosphatidylcholine synthase activity
AW166_RS06450	COG2376	Dihydroxyacetone kinase
AW166_RS06460	COG2376	Dihydroxyacetone kinase
AW166_RS06465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW166_RS06470	COG1959	2 iron, 2 sulfur cluster binding
AW166_RS06495	COG2770	Histidine kinase
AW166_RS06495	COG3437	response regulator, receiver
AW166_RS06545	COG3237	CsbD-like
AW166_RS06570	COG1191	sigma factor activity
AW166_RS06580	COG2208	phosphoserine phosphatase activity
AW166_RS06585	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW166_RS06590	COG0784	Response regulator, receiver
AW166_RS06590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_RS06590	COG2198	Histidine kinase
AW166_RS06590	COG2205	protein histidine kinase activity
AW166_RS06650	COG0420	3'-5' exonuclease activity
AW166_RS06655	COG4717	serine-type aminopeptidase activity
AW166_RS06675	COG1309	transcriptional regulator
AW166_RS06680	COG2814	Major facilitator Superfamily
AW166_RS06685	COG0346	lactoylglutathione lyase activity
AW166_RS06690	COG0346	lactoylglutathione lyase activity
AW166_RS06695	COG0457	Tetratricopeptide repeat
AW166_RS06700	COG2267	carboxylic ester hydrolase activity
AW166_RS06720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW166_RS06725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW166_RS06735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW166_RS06775	COG0477	Major facilitator Superfamily
AW166_RS06780	COG0477	Major facilitator Superfamily
AW166_RS06790	COG3973	AAA domain
AW166_RS06795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW166_RS06820	COG4980	gas vesicle protein
AW166_RS06825	COG0537	adenosine 5'-monophosphoramidase activity
AW166_RS06830	COG1131	(ABC) transporter
AW166_RS06835	COG4473	ABC transporter
AW166_RS06845	COG1309	transcriptional regulator
AW166_RS06855	COG3402	PFAM membrane-flanked domain
AW166_RS06865	COG3428	Bacterial PH domain
AW166_RS06905	COG3402	PFAM membrane-flanked domain
AW166_RS06910	COG3428	Bacterial PH domain
AW166_RS06915	COG2329	Antibiotic biosynthesis monooxygenase
AW166_RS06920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_RS06925	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW166_RS06930	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AW166_RS06935	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AW166_RS06970	COG1309	transcriptional regulator
AW166_RS06975	COG1511	domain protein
AW166_RS07000	COG1609	Transcriptional regulator
AW166_RS07010	COG1234	tRNA 3'-trailer cleavage
AW166_RS07015	COG0095	Lipoate-protein ligase
AW166_RS07025	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_RS07055	COG3209	COG3209 Rhs family protein
AW166_RS07100	COG1408	metallophosphoesterase
AW166_RS07105	COG1078	dGTPase activity
AW166_RS07115	COG1595	DNA-templated transcription, initiation
AW166_RS07120	COG3708	Transcriptional regulator
AW166_RS07120	COG2207	Transcriptional regulator
AW166_RS07135	COG2205	protein histidine kinase activity
AW166_RS07140	COG0745	RESPONSE REGULATOR receiver
AW166_RS07165	COG0501	Belongs to the peptidase M48B family
AW166_RS07170	COG0840	transmembrane signaling receptor activity
AW166_RS07175	COG0697	spore germination
AW166_RS07195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AW166_RS07200	COG2224	Isocitrate lyase
AW166_RS07225	COG4903	ComK protein
AW166_RS07230	COG0398	Pfam SNARE associated Golgi protein
AW166_RS07240	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AW166_RS07245	COG1074	ATP-dependent DNA helicase activity
AW166_RS07290	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW166_RS07315	COG0367	asparagine synthase
AW166_RS07320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AW166_RS07325	COG0753	catalase activity
AW166_RS07330	COG0004	ammonium transporteR
AW166_RS07355	COG2996	Protein conserved in bacteria
AW166_RS07365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW166_RS07375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS07390	COG0561	phosphatase activity
AW166_RS07405	COG0542	response to heat
AW166_RS07415	COG2267	carboxylic ester hydrolase activity
AW166_RS07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_RS07435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW166_RS07440	COG5504	Zn-dependent protease
AW166_RS07450	COG0180	Tryptophanyl-tRNA synthetase
AW166_RS07460	COG4166	transmembrane transport
AW166_RS07465	COG0601	transmembrane transport
AW166_RS07470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_RS07475	COG0444	Belongs to the ABC transporter superfamily
AW166_RS07480	COG4608	Belongs to the ABC transporter superfamily
AW166_RS07485	COG0534	Mate efflux family protein
AW166_RS07490	COG4166	transmembrane transport
AW166_RS07510	COG0861	Integral membrane protein TerC family
AW166_RS07515	COG4862	establishment of competence for transformation
AW166_RS07520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_RS07530	COG1164	Oligoendopeptidase f
AW166_RS07540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW166_RS07545	COG2346	COG2346, Truncated hemoglobins
AW166_RS07550	COG4116	CYTH
AW166_RS07560	COG2357	RelA SpoT domain protein
AW166_RS07570	COG0564	pseudouridine synthase activity
AW166_RS07585	COG0772	Belongs to the SEDS family
AW166_RS07590	COG1216	Glycosyl transferase, family 2
AW166_RS07590	COG0463	Glycosyl transferase, family 2
AW166_RS07610	COG0457	Tetratricopeptide repeat
AW166_RS07610	COG0463	Glycosyl transferase, family 2
AW166_RS07630	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW166_RS07645	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW166_RS07690	COG2153	protein acetylation
AW166_RS07700	COG2382	esterase
AW166_RS07715	COG5492	domain, Protein
AW166_RS07720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_RS07735	COG0512	Glutamine amidotransferase of anthranilate synthase
AW166_RS07735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW166_RS07770	COG1620	l-lactate permease
AW166_RS07775	COG5634	Uncharacterized conserved protein (DUF2278)
AW166_RS07825	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_RS07835	COG1476	TRANSCRIPTIONal
AW166_RS07895	COG2226	methyltransferase
AW166_RS07905	COG1686	Belongs to the peptidase S11 family
AW166_RS07910	COG0681	Belongs to the peptidase S26 family
AW166_RS07945	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS07950	COG3842	ATPase activity
AW166_RS07955	COG1176	ABC-type spermidine putrescine transport system, permease component I
AW166_RS07960	COG1177	transmembrane transport
AW166_RS07965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AW166_RS07975	COG2409	Drug exporters of the RND superfamily
AW166_RS07985	COG0564	pseudouridine synthase activity
AW166_RS07995	COG2340	Cysteine-rich secretory protein family
AW166_RS08000	COG0247	lactate metabolic process
AW166_RS08005	COG0277	FAD linked oxidase domain protein
AW166_RS08010	COG3835	regulator
AW166_RS08020	COG0745	RESPONSE REGULATOR receiver
AW166_RS08025	COG5002	protein histidine kinase activity
AW166_RS08030	COG2186	Transcriptional regulator
AW166_RS08050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW166_RS08060	COG2116	formate transmembrane transporter activity
AW166_RS08065	COG0861	Integral membrane protein TerC family
AW166_RS08070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW166_RS08080	COG2030	dehydratase
AW166_RS08100	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS08105	COG3243	poly(R)-hydroxyalkanoic acid synthase
AW166_RS08115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW166_RS08130	COG1840	ABC-type Fe3 transport system, periplasmic component
AW166_RS08160	COG1349	DNA-binding transcription factor activity
AW166_RS08185	COG2861	carbohydrate metabolic process
AW166_RS08195	COG3852	Histidine kinase
AW166_RS08200	COG1846	Transcriptional regulator
AW166_RS08210	COG2318	DinB family
AW166_RS08220	COG5002	protein histidine kinase activity
AW166_RS08230	COG0720	synthase
AW166_RS08245	COG4873	Protein conserved in bacteria
AW166_RS08280	COG1780	Probably involved in ribonucleotide reductase function
AW166_RS08295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW166_RS08300	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW166_RS08305	COG1725	Transcriptional regulator
AW166_RS08310	COG1131	(ABC) transporter
AW166_RS08320	COG1131	(ABC) transporter
AW166_RS08325	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW166_RS08340	COG1522	sequence-specific DNA binding
AW166_RS08350	COG1335	isochorismatase
AW166_RS08360	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW166_RS08365	COG2070	2-Nitropropane dioxygenase
AW166_RS08370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW166_RS08380	COG1696	Membrane protein involved in D-alanine export
AW166_RS08405	COG0716	FMN binding
AW166_RS08420	COG3173	Aminoglycoside phosphotransferase
AW166_RS08440	COG0534	Mate efflux family protein
AW166_RS08445	COG1968	undecaprenyl-diphosphatase activity
AW166_RS08460	COG1846	Transcriptional regulator
AW166_RS08470	COG1301	dicarboxylic acid transport
AW166_RS08475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW166_RS08480	COG4709	membrane
AW166_RS08485	COG3874	Sporulation protein YtfJ
AW166_RS08515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_RS08520	COG0028	Belongs to the TPP enzyme family
AW166_RS08525	COG0440	acetolactate synthase activity
AW166_RS08530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW166_RS08540	COG0473	3-isopropylmalate dehydrogenase activity
AW166_RS08565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW166_RS08600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW166_RS08615	COG1183	phosphatidylcholine synthase activity
AW166_RS08620	COG1368	sulfuric ester hydrolase activity
AW166_RS08630	COG0019	diaminopimelate decarboxylase activity
AW166_RS08650	COG0529	Catalyzes the synthesis of activated sulfate
AW166_RS08655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW166_RS08675	COG1648	precorrin-2 dehydrogenase activity
AW166_RS08685	COG0733	neurotransmitter:sodium symporter activity
AW166_RS08705	COG1757	Na H antiporter
AW166_RS08720	COG4758	membrane
AW166_RS08725	COG4585	Histidine kinase
AW166_RS08730	COG2197	response regulator
AW166_RS08740	COG1114	Component of the transport system for branched-chain amino acids
AW166_RS08750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW166_RS08775	COG1017	nitric oxide dioxygenase activity
AW166_RS08775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW166_RS08795	COG0730	response to heat
AW166_RS08800	COG0306	phosphate transporter
AW166_RS08805	COG1392	Phosphate transport regulator
AW166_RS08810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_RS08825	COG3852	Histidine kinase
AW166_RS08830	COG1801	Protein of unknown function DUF72
AW166_RS08840	COG0582	viral genome integration into host DNA
AW166_RS08845	COG5002	protein histidine kinase activity
AW166_RS08865	COG0392	lysyltransferase activity
AW166_RS08865	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW166_RS08880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW166_RS08885	COG1686	Belongs to the peptidase S11 family
AW166_RS08890	COG2715	membrane protein required for spore maturation
AW166_RS08895	COG0700	Nucleoside recognition
AW166_RS08900	COG1187	pseudouridine synthase activity
AW166_RS08910	COG1333	cytochrome c biogenesis protein
AW166_RS08915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW166_RS08920	COG0745	RESPONSE REGULATOR receiver
AW166_RS08925	COG5002	protein histidine kinase activity
AW166_RS08930	COG2096	Adenosyltransferase
AW166_RS08945	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW166_RS08950	COG1141	Ferredoxin
AW166_RS08955	COG4955	Helix-turn-helix domain
AW166_RS08960	COG0514	ATP-dependent DNA helicase (RecQ)
AW166_RS08965	COG1266	CAAX protease self-immunity
AW166_RS08985	COG4862	establishment of competence for transformation
AW166_RS08990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW166_RS09010	COG0492	ferredoxin-NADP+ reductase activity
AW166_RS09015	COG0252	asparaginase activity
AW166_RS09085	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW166_RS09100	COG0142	geranyltranstransferase activity
AW166_RS09110	COG0142	geranyltranstransferase activity
AW166_RS09130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW166_RS09135	COG0457	Tetratricopeptide repeat
AW166_RS09155	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW166_RS09165	COG4347	Protein of unknown function (DUF1405)
AW166_RS09180	COG2738	Putative neutral zinc metallopeptidase
AW166_RS09190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS09200	COG1694	Mazg nucleotide pyrophosphohydrolase
AW166_RS09215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW166_RS09220	COG0438	transferase activity, transferring glycosyl groups
AW166_RS09260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW166_RS09260	COG1199	ATP-dependent helicase activity
AW166_RS09280	COG3935	DnaD domain protein
AW166_RS09285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW166_RS09295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_RS09295	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW166_RS09350	COG0116	Belongs to the methyltransferase superfamily
AW166_RS09360	COG1199	ATP-dependent helicase activity
AW166_RS09365	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW166_RS09375	COG3173	Aminoglycoside phosphotransferase
AW166_RS09380	COG0024	Methionine aminopeptidase
AW166_RS09390	COG2233	PERMEase
AW166_RS09395	COG2311	Membrane
AW166_RS09400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW166_RS09410	COG0456	acetyltransferase
AW166_RS09445	COG0754	glutathionylspermidine amidase activity
AW166_RS09460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW166_RS09485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW166_RS09500	COG1215	transferase activity, transferring glycosyl groups
AW166_RS09520	COG0454	-acetyltransferase
AW166_RS09540	COG0328	RNA-DNA hybrid ribonuclease activity
AW166_RS09580	COG1280	lysine exporter protein (LysE YggA)
AW166_RS09595	COG3162	membrane
AW166_RS09600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_RS09605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW166_RS09615	COG0475	glutathione-regulated potassium exporter activity
AW166_RS09625	COG0789	Transcriptional regulator
AW166_RS09625	COG4978	Transcriptional regulator
AW166_RS09635	COG2323	membrane
AW166_RS09640	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW166_RS09695	COG1923	regulation of RNA biosynthetic process
AW166_RS09705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW166_RS09710	COG1360	Flagellar Motor Protein
AW166_RS09715	COG2201	protein-glutamate methylesterase activity
AW166_RS09725	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW166_RS09725	COG1776	CheC inhibitor of MCP methylation
AW166_RS09740	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW166_RS09760	COG1256	bacterial-type flagellum assembly
AW166_RS09765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW166_RS09790	COG1815	bacterial-type flagellum-dependent cell motility
AW166_RS09795	COG1558	bacterial-type flagellum-dependent cell motility
AW166_RS09805	COG1766	The M ring may be actively involved in energy transduction
AW166_RS09815	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW166_RS09825	COG1157	protein secretion by the type III secretion system
AW166_RS09875	COG0463	Glycosyl transferase, family 2
AW166_RS09905	COG0457	Tetratricopeptide repeat
AW166_RS09905	COG0463	Glycosyl transferase, family 2
AW166_RS09930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW166_RS09935	COG0741	lytic transglycosylase activity
AW166_RS09950	COG1776	CheC inhibitor of MCP methylation
AW166_RS09950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW166_RS09960	COG1338	Plays a role in the flagellum-specific transport system
AW166_RS09965	COG1987	bacterial-type flagellum assembly
AW166_RS09975	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW166_RS09980	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW166_RS09990	COG4786	Flagellar basal body rod
AW166_RS09995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW166_RS10020	COG1309	transcriptional regulator
AW166_RS10040	COG2329	Antibiotic biosynthesis monooxygenase
AW166_RS10065	COG0583	DNA-binding transcription factor activity
AW166_RS10070	COG3842	ATPase activity
AW166_RS10075	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW166_RS10085	COG1234	tRNA 3'-trailer cleavage
AW166_RS10110	COG1686	Belongs to the peptidase S11 family
AW166_RS10120	COG0406	alpha-ribazole phosphatase activity
AW166_RS10150	COG0367	asparagine synthase
AW166_RS10180	COG1802	Transcriptional regulator
AW166_RS10185	COG0697	spore germination
AW166_RS10190	COG0523	cobalamin synthesis protein
AW166_RS10195	COG0701	Predicted permease
AW166_RS10205	COG1216	Glycosyl transferase, family 2
AW166_RS10205	COG0438	transferase activity, transferring glycosyl groups
AW166_RS10210	COG1757	Na H antiporter
AW166_RS10215	COG0114	fumarate hydratase activity
AW166_RS10245	COG3340	Belongs to the peptidase S51 family
AW166_RS10265	COG0785	Cytochrome C biogenesis protein
AW166_RS10300	COG2733	membrane
AW166_RS10335	COG1131	(ABC) transporter
AW166_RS10350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_RS10355	COG0528	UMP kinase activity
AW166_RS10365	COG1027	Aspartate ammonia-lyase
AW166_RS10370	COG0281	malic enzyme
AW166_RS10375	COG4191	Histidine kinase
AW166_RS10380	COG0784	Response regulator, receiver
AW166_RS10385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW166_RS10445	COG1051	belongs to the nudix hydrolase family
AW166_RS10450	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_RS10460	COG2814	Major facilitator Superfamily
AW166_RS10475	COG1966	Carbon starvation protein
AW166_RS10490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_RS10500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW166_RS10510	COG4166	transmembrane transport
AW166_RS10515	COG2223	nitrite transmembrane transporter activity
AW166_RS10520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW166_RS10535	COG2244	polysaccharide biosynthetic process
AW166_RS10540	COG0733	neurotransmitter:sodium symporter activity
AW166_RS10550	COG5566	PFAM Mor transcription activator
AW166_RS10555	COG2323	membrane
AW166_RS10570	COG2084	Dehydrogenase
AW166_RS10585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW166_RS10595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_RS10600	COG0028	Belongs to the TPP enzyme family
AW166_RS10605	COG0440	acetolactate synthase activity
AW166_RS10610	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW166_RS10620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW166_RS10645	COG2814	Major facilitator Superfamily
AW166_RS10650	COG3384	dioxygenase
AW166_RS10660	COG3279	Response regulator of the LytR AlgR family
AW166_RS10665	COG0427	acetyl-CoA hydrolase
AW166_RS10685	COG1073	alpha beta
AW166_RS10690	COG4166	transmembrane transport
AW166_RS10715	COG0535	radical SAM domain protein
AW166_RS10720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS10740	COG1914	H( )-stimulated, divalent metal cation uptake system
AW166_RS10755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW166_RS10790	COG2390	Transcriptional regulator
AW166_RS10800	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS10805	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW166_RS10820	COG4224	UPF0291 protein
AW166_RS10840	COG0006	proline dipeptidase activity
AW166_RS10845	COG2132	Multicopper oxidase
AW166_RS10860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW166_RS10875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW166_RS10890	COG1276	copper resistance
AW166_RS10890	COG2372	response to copper ion
AW166_RS10895	COG4549	nuclear export factor GLE1
AW166_RS10905	COG0697	spore germination
AW166_RS10910	COG0583	DNA-binding transcription factor activity
AW166_RS10915	COG1959	2 iron, 2 sulfur cluster binding
AW166_RS10920	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW166_RS10925	COG0778	Nitroreductase
AW166_RS10940	COG0628	permease
AW166_RS10950	COG1231	oxidoreductase activity
AW166_RS10955	COG0523	cobalamin synthesis protein
AW166_RS10970	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_RS10975	COG2030	dehydratase
AW166_RS10980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_RS10990	COG0411	ABC transporter
AW166_RS11010	COG0583	DNA-binding transcription factor activity
AW166_RS11020	COG1942	4-Oxalocrotonate Tautomerase
AW166_RS11030	COG1846	Transcriptional regulator
AW166_RS11040	COG1271	oxidase subunit
AW166_RS11045	COG1294	oxidase, subunit
AW166_RS11050	COG4988	ABC transporter
AW166_RS11055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW166_RS11075	COG1686	Belongs to the peptidase S11 family
AW166_RS11090	COG0791	NLP P60 protein
AW166_RS11090	COG1388	LysM domain
AW166_RS11100	COG1132	(ABC) transporter
AW166_RS11105	COG1132	(ABC) transporter
AW166_RS11110	COG0745	RESPONSE REGULATOR receiver
AW166_RS11115	COG5002	protein histidine kinase activity
AW166_RS11125	COG0300	oxidoreductase activity
AW166_RS11160	COG0460	homoserine dehydrogenase
AW166_RS11185	COG1316	TRANSCRIPTIONal
AW166_RS11195	COG0745	RESPONSE REGULATOR receiver
AW166_RS11200	COG5002	protein histidine kinase activity
AW166_RS11215	COG1285	pathogenesis
AW166_RS11220	COG1247	-acetyltransferase
AW166_RS11240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW166_RS11250	COG1082	Xylose isomerase domain protein TIM barrel
AW166_RS11265	COG1279	arginine transmembrane transporter activity
AW166_RS11275	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW166_RS11315	COG2002	toxin-antitoxin pair type II binding
AW166_RS11320	COG1404	Belongs to the peptidase S8 family
AW166_RS11325	COG0640	Transcriptional regulator
AW166_RS11330	COG0667	Aldo Keto reductase
AW166_RS11335	COG2814	Major facilitator Superfamily
AW166_RS11360	COG0840	transmembrane signaling receptor activity
AW166_RS11380	COG3949	Membrane
AW166_RS11385	COG0783	Belongs to the Dps family
AW166_RS11400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW166_RS11410	COG1231	oxidoreductase activity
AW166_RS11420	COG4989	oxidoreductase activity
AW166_RS11425	COG0523	cobalamin synthesis protein
AW166_RS11430	COG0456	acetyltransferase
AW166_RS11490	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW166_RS11490	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW166_RS11500	COG0702	epimerase
AW166_RS11510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW166_RS11520	COG4166	transmembrane transport
AW166_RS11535	COG0406	alpha-ribazole phosphatase activity
AW166_RS11545	COG5337	Spore coat protein CotH
AW166_RS11550	COG1051	belongs to the nudix hydrolase family
AW166_RS11555	COG0586	Pfam SNARE associated Golgi protein
AW166_RS11560	COG2244	polysaccharide biosynthetic process
AW166_RS11570	COG0701	Predicted permease
AW166_RS11575	COG3689	TIGRFAM TIGR03943 family protein
AW166_RS11580	COG1607	acyl-coa hydrolase
AW166_RS11585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_RS11600	COG0702	epimerase
AW166_RS11605	COG2839	Protein conserved in bacteria
AW166_RS11610	COG1253	flavin adenine dinucleotide binding
AW166_RS11625	COG1114	Component of the transport system for branched-chain amino acids
AW166_RS11630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_RS11650	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_RS11660	COG1876	peptidase activity
AW166_RS11670	COG0154	amidase activity
AW166_RS11675	COG2211	Major facilitator Superfamily
AW166_RS11695	COG0561	phosphatase activity
AW166_RS11705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW166_RS11710	COG4106	trans-aconitate 2-methyltransferase activity
AW166_RS11725	COG1819	glycosyl
AW166_RS11730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS11735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS11760	COG0456	acetyltransferase
AW166_RS11810	COG3874	Sporulation protein YtfJ
AW166_RS11835	COG2226	methyltransferase
AW166_RS11855	COG1082	Xylose isomerase domain protein TIM barrel
AW166_RS11860	COG0346	lactoylglutathione lyase activity
AW166_RS11870	COG0604	alcohol dehydrogenase
AW166_RS11875	COG1595	DNA-templated transcription, initiation
AW166_RS11900	COG0386	Belongs to the glutathione peroxidase family
AW166_RS11905	COG1305	Transglutaminase-like
AW166_RS11910	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW166_RS11915	COG0714	Associated with various cellular activities
AW166_RS11930	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW166_RS11935	COG1140	nitrate reductase beta subunit
AW166_RS11940	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW166_RS11945	COG2181	nitrate reductase activity
AW166_RS11965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW166_RS11970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW166_RS11975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_RS11980	COG0303	'Molybdopterin
AW166_RS11985	COG0314	molybdopterin synthase activity
AW166_RS11995	COG2223	nitrite transmembrane transporter activity
AW166_RS12010	COG1648	precorrin-2 dehydrogenase activity
AW166_RS12020	COG1587	Uroporphyrinogen-III synthase
AW166_RS12020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW166_RS12025	COG2146	nitrite reductase [NAD(P)H] activity
AW166_RS12030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW166_RS12035	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AW166_RS12070	COG2359	stage V sporulation protein S
AW166_RS12085	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW166_RS12100	COG1418	mRNA catabolic process
AW166_RS12105	COG0488	(ABC) transporter
AW166_RS12120	COG0629	single-stranded DNA binding
AW166_RS12135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW166_RS12140	COG1413	lyase activity
AW166_RS12155	COG2136	Putative SAM-dependent methyltransferase
AW166_RS12155	COG2521	methyltransferase
AW166_RS12160	COG0018	arginyl-trna synthetase
AW166_RS12185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW166_RS12200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW166_RS12205	COG0017	Asparaginyl-tRNA synthetase
AW166_RS12225	COG1674	ftsk spoiiie
AW166_RS12325	COG1929	Belongs to the glycerate kinase type-1 family
AW166_RS12330	COG0471	metal ion transport
AW166_RS12335	COG0745	RESPONSE REGULATOR receiver
AW166_RS12340	COG3850	Histidine kinase
AW166_RS12340	COG5002	protein histidine kinase activity
AW166_RS12355	COG0733	neurotransmitter:sodium symporter activity
AW166_RS12380	COG2610	gluconate transmembrane transporter activity
AW166_RS12385	COG1454	alcohol dehydrogenase
AW166_RS12390	COG1794	racemase activity, acting on amino acids and derivatives
AW166_RS12400	COG0456	acetyltransferase
AW166_RS12415	COG1131	(ABC) transporter
AW166_RS12420	COG4473	ABC transporter
AW166_RS12430	COG0546	phosphoglycolate phosphatase activity
AW166_RS12450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_RS12465	COG0768	penicillin binding
AW166_RS12470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW166_RS12475	COG0204	Acyl-transferase
AW166_RS12480	COG1272	protein, Hemolysin III
AW166_RS12490	COG0805	protein transport
AW166_RS12500	COG1307	EDD domain protein, DegV family
AW166_RS12505	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AW166_RS12510	COG1999	signal sequence binding
AW166_RS12515	COG0071	Belongs to the small heat shock protein (HSP20) family
AW166_RS12520	COG0367	asparagine synthase
AW166_RS12540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS12545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW166_RS12580	COG0668	transmembrane transport
AW166_RS12585	COG2203	Gaf domain
AW166_RS12585	COG4585	Histidine kinase
AW166_RS12590	COG2197	response regulator
AW166_RS12600	COG1737	Transcriptional regulator
AW166_RS12605	COG1064	alcohol dehydrogenase
AW166_RS12635	COG1070	Carbohydrate kinase
AW166_RS12640	COG1070	Carbohydrate kinase
AW166_RS12670	COG0517	IMP dehydrogenase activity
AW166_RS12670	COG1125	glycine betaine transport
AW166_RS12675	COG1174	glycine betaine transport
AW166_RS12710	COG1253	flavin adenine dinucleotide binding
AW166_RS12715	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS12720	COG5506	Protein of unknown function (DUF1694)
AW166_RS12735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW166_RS12740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW166_RS12745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW166_RS12750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_RS12755	COG0456	acetyltransferase
AW166_RS12760	COG3829	transcription factor binding
AW166_RS12765	COG1509	lysine 2,3-aminomutase activity
AW166_RS12805	COG4326	sporulation control protein
AW166_RS12810	COG0671	phosphoesterase, PA-phosphatase related
AW166_RS12815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW166_RS12820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_RS12850	COG1715	Restriction endonuclease
AW166_RS12850	COG1787	Restriction endonuclease
AW166_RS12935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW166_RS12975	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW166_RS12975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_RS12985	COG2814	Major facilitator Superfamily
AW166_RS12990	COG4841	protein insertion into membrane
AW166_RS12995	COG0372	Belongs to the citrate synthase family
AW166_RS13000	COG2079	MmgE PrpD family protein
AW166_RS13005	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW166_RS13010	COG1960	acyl-CoA dehydrogenase activity
AW166_RS13015	COG2084	Dehydrogenase
AW166_RS13025	COG1280	lysine exporter protein (LysE YggA)
AW166_RS13030	COG1024	Enoyl-CoA hydratase
AW166_RS13045	COG0420	3'-5' exonuclease activity
AW166_RS13050	COG0419	ATPase involved in DNA repair
AW166_RS13080	COG2223	nitrite transmembrane transporter activity
AW166_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS13090	COG1169	isochorismate synthase
AW166_RS13095	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW166_RS13100	COG1535	isochorismatase
AW166_RS13100	COG3433	isochorismatase activity
AW166_RS13105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW166_RS13110	COG3251	PFAM MbtH domain protein
AW166_RS13115	COG2814	Major facilitator Superfamily
AW166_RS13130	COG0776	regulation of translation
AW166_RS13140	COG2318	DinB family
AW166_RS13150	COG1115	amino acid carrier protein
AW166_RS13165	COG2329	Antibiotic biosynthesis monooxygenase
AW166_RS13170	COG1187	pseudouridine synthase activity
AW166_RS13175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW166_RS13190	COG0596	Alpha beta hydrolase
AW166_RS13195	COG2814	Major facilitator Superfamily
AW166_RS13215	COG2226	methyltransferase
AW166_RS13260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS13295	COG1247	-acetyltransferase
AW166_RS13325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AW166_RS13335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS13345	COG1278	Cold shock
AW166_RS13360	COG0010	Belongs to the arginase family
AW166_RS13365	COG0561	phosphatase activity
AW166_RS13410	COG0583	DNA-binding transcription factor activity
AW166_RS13415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW166_RS13430	COG0583	DNA-binding transcription factor activity
AW166_RS13435	COG2258	MOSC domain
AW166_RS13450	COG1132	(ABC) transporter
AW166_RS13455	COG1132	(ABC) transporter
AW166_RS13475	COG1396	sequence-specific DNA binding
AW166_RS13500	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AW166_RS13505	COG1595	DNA-templated transcription, initiation
AW166_RS13555	COG2971	BadF BadG BcrA BcrD
AW166_RS13560	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW166_RS13565	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW166_RS13585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS13615	COG1309	transcriptional regulator
AW166_RS13630	COG1136	(ABC) transporter
AW166_RS13630	COG0577	efflux transmembrane transporter activity
AW166_RS13635	COG3615	Tellurite resistance protein tehB
AW166_RS13635	COG0500	methyltransferase
AW166_RS13645	COG2226	methyltransferase
AW166_RS13650	COG3961	Belongs to the TPP enzyme family
AW166_RS13655	COG1846	Transcriptional regulator
AW166_RS13695	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW166_RS13710	COG1595	DNA-templated transcription, initiation
AW166_RS13720	COG0768	penicillin binding
AW166_RS13730	COG2367	Beta-lactamase
AW166_RS13735	COG0671	phosphoesterase, PA-phosphatase related
AW166_RS13740	COG1609	Transcriptional regulator
AW166_RS13745	COG2814	Major facilitator Superfamily
AW166_RS13750	COG0673	inositol 2-dehydrogenase activity
AW166_RS13760	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS13775	COG0191	fructose-bisphosphate aldolase activity
AW166_RS13780	COG3718	enzyme involved in inositol metabolism
AW166_RS13805	COG0457	Tetratricopeptide repeat
AW166_RS13810	COG1476	TRANSCRIPTIONal
AW166_RS13825	COG1876	peptidase activity
AW166_RS13845	COG1309	transcriptional regulator
AW166_RS13850	COG0488	(ABC) transporter
AW166_RS13865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS13875	COG1252	NADH dehydrogenase
AW166_RS13880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_RS13895	COG1131	(ABC) transporter
AW166_RS13905	COG1309	transcriptional regulator
AW166_RS13920	COG1960	acyl-CoA dehydrogenase activity
AW166_RS13925	COG0439	Biotin carboxylase
AW166_RS13930	COG0511	ligase activity, forming carbon-carbon bonds
AW166_RS13935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW166_RS13940	COG1024	Enoyl-CoA hydratase
AW166_RS13945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW166_RS13950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW166_RS13960	COG1247	-acetyltransferase
AW166_RS13965	COG0572	uridine kinase
AW166_RS13975	COG2318	DinB family
AW166_RS13980	COG1686	Belongs to the peptidase S11 family
AW166_RS14005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW166_RS14045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW166_RS14045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW166_RS14070	COG2814	Major facilitator Superfamily
AW166_RS14090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW166_RS14110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS14125	COG1063	alcohol dehydrogenase
AW166_RS14140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW166_RS14145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW166_RS14160	COG3773	Cell wall hydrolase
AW166_RS14170	COG0745	RESPONSE REGULATOR receiver
AW166_RS14200	COG1136	(ABC) transporter
AW166_RS14225	COG0460	homoserine dehydrogenase
AW166_RS14230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS14240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW166_RS14315	COG2124	cytochrome p450
AW166_RS14350	COG0561	phosphatase activity
AW166_RS14360	COG5002	protein histidine kinase activity
AW166_RS14365	COG0768	penicillin binding
AW166_RS14370	COG1819	glycosyl
AW166_RS14375	COG1794	racemase activity, acting on amino acids and derivatives
AW166_RS14385	COG1122	ATPase activity
AW166_RS14395	COG2205	protein histidine kinase activity
AW166_RS14405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_RS14410	COG0604	alcohol dehydrogenase
AW166_RS14415	COG0768	penicillin binding
AW166_RS14425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_RS14460	COG0693	protein deglycase activity
AW166_RS14490	COG2814	Major facilitator Superfamily
AW166_RS14505	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_RS14525	COG0697	spore germination
AW166_RS14550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_RS14560	COG2223	nitrite transmembrane transporter activity
AW166_RS14575	COG2816	NAD+ diphosphatase activity
AW166_RS14580	COG0592	DNA-directed DNA polymerase activity
AW166_RS14585	COG1051	belongs to the nudix hydrolase family
AW166_RS14620	COG3878	Protein conserved in bacteria
AW166_RS14650	COG4667	esterase of the alpha-beta hydrolase superfamily
AW166_RS14675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW166_RS14690	COG0322	excinuclease ABC activity
AW166_RS14730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_RS14755	COG1011	Hydrolase
AW166_RS14775	COG0076	glutamate decarboxylase activity
AW166_RS14790	COG1523	belongs to the glycosyl hydrolase 13 family
AW166_RS14795	COG3227	Zinc metalloprotease (Elastase)
AW166_RS14815	COG0201	protein transport
AW166_RS14825	COG0697	spore germination
AW166_RS14830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS14860	COG4129	membrane
AW166_RS14865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS14880	COG2959	enzyme of heme biosynthesis
AW166_RS14900	COG3483	tryptophan 2,3-dioxygenase activity
AW166_RS14905	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AW166_RS14910	COG3844	kynureninase activity
AW166_RS14915	COG1309	transcriptional regulator
AW166_RS14945	COG3284	Transcriptional regulator
AW166_RS14965	COG1349	DNA-binding transcription factor activity
AW166_RS14985	COG1959	2 iron, 2 sulfur cluster binding
AW166_RS15000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW166_RS15005	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_RS15010	COG0022	dehydrogenase e1 component
AW166_RS15015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW166_RS15025	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS15030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_RS15030	COG0456	acetyltransferase
AW166_RS15065	COG4176	ABC-type proline glycine betaine transport system permease component
AW166_RS15070	COG4175	Glycine betaine
AW166_RS15070	COG0517	IMP dehydrogenase activity
AW166_RS15095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AW166_RS15100	COG2153	protein acetylation
AW166_RS15105	COG3397	chitin binding
AW166_RS15120	COG2205	protein histidine kinase activity
AW166_RS15150	COG2333	competence protein COMEC
AW166_RS15150	COG0658	competence protein
AW166_RS15200	COG3973	AAA domain
AW166_RS15215	COG2105	PFAM AIG2 family protein
AW166_RS15220	COG0514	ATP-dependent DNA helicase (RecQ)
AW166_RS15250	COG4637	Psort location Cytoplasmic, score
AW166_RS15275	COG3397	chitin binding
AW166_RS15285	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW166_RS15290	COG1115	amino acid carrier protein
AW166_RS15295	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS15300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW166_RS15310	COG3938	Belongs to the proline racemase family
AW166_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW166_RS15355	COG0586	Pfam SNARE associated Golgi protein
AW166_RS15370	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW166_RS15375	COG0519	Catalyzes the synthesis of GMP from XMP
AW166_RS15380	COG4166	transmembrane transport
AW166_RS15390	COG4948	Mandelate Racemase Muconate Lactonizing
AW166_RS15430	COG2936	dipeptidyl-peptidase activity
AW166_RS15435	COG5002	protein histidine kinase activity
AW166_RS15440	COG0745	RESPONSE REGULATOR receiver
AW166_RS15480	COG1307	EDD domain protein, DegV family
AW166_RS15500	COG2814	Major facilitator Superfamily
AW166_RS15510	COG1664	Polymer-forming cytoskeletal
AW166_RS15515	COG0789	Transcriptional regulator
AW166_RS15520	COG4533	DNA binding
AW166_RS15525	COG2814	Major facilitator Superfamily
AW166_RS15525	COG0477	Major facilitator Superfamily
AW166_RS15545	COG2261	transglycosylase associated protein
AW166_RS15560	COG2226	methyltransferase
AW166_RS15595	COG0436	Aminotransferase
AW166_RS15600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW166_RS15605	COG5146	pantothenate kinase activity
AW166_RS15630	COG1131	(ABC) transporter
AW166_RS15680	COG0628	permease
AW166_RS15695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW166_RS15700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_RS15705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW166_RS15710	COG1116	anion transmembrane transporter activity
AW166_RS15730	COG2816	NAD+ diphosphatase activity
AW166_RS15750	COG2746	aminoglycoside 3-N-acetyltransferase activity
AW166_RS15775	COG0697	spore germination
AW166_RS15780	COG2318	DinB family
AW166_RS15800	COG4912	Dna alkylation repair
AW166_RS15820	COG0861	Integral membrane protein TerC family
AW166_RS15825	COG1368	sulfuric ester hydrolase activity
AW166_RS15830	COG0488	(ABC) transporter
AW166_RS15840	COG2409	Drug exporters of the RND superfamily
AW166_RS15840	COG1033	growth of symbiont in host cell
AW166_RS15845	COG2409	Drug exporters of the RND superfamily
AW166_RS15845	COG1033	growth of symbiont in host cell
AW166_RS15850	COG1033	growth of symbiont in host cell
AW166_RS15850	COG2409	Drug exporters of the RND superfamily
AW166_RS15855	COG1309	transcriptional regulator
AW166_RS15870	COG0287	Prephenate dehydrogenase
AW166_RS15875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW166_RS15880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW166_RS15885	COG1605	Chorismate mutase
AW166_RS15885	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW166_RS15920	COG3584	3D domain protein
AW166_RS15920	COG1388	LysM domain
AW166_RS15930	COG1595	DNA-templated transcription, initiation
AW166_RS15955	COG1879	ABC-type sugar transport system periplasmic component
AW166_RS15965	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW166_RS15975	COG2390	Transcriptional regulator
AW166_RS16010	COG2329	Antibiotic biosynthesis monooxygenase
AW166_RS16030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS16040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW166_RS16045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_RS16050	COG4187	Peptidase family M20/M25/M40
AW166_RS16055	COG1414	Transcriptional regulator
AW166_RS16060	COG0833	amino acid
AW166_RS16065	COG1690	Belongs to the RtcB family
AW166_RS16070	COG3239	Fatty acid desaturase
AW166_RS16075	COG1785	Belongs to the alkaline phosphatase family
AW166_RS16085	COG3655	Transcriptional regulator
AW166_RS16100	COG4377	Putative membrane peptidase family (DUF2324)
AW166_RS16110	COG3279	Response regulator of the LytR AlgR family
AW166_RS16120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS16125	COG0346	lactoylglutathione lyase activity
AW166_RS16145	COG0714	Associated with various cellular activities
AW166_RS16170	COG0463	Glycosyl transferase, family 2
AW166_RS16195	COG0463	Glycosyl transferase, family 2
AW166_RS16205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW166_RS16210	COG0753	catalase activity
AW166_RS16220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW166_RS16245	COG0714	Associated with various cellular activities
AW166_RS16255	COG0778	Nitroreductase
AW166_RS16260	COG1846	Transcriptional regulator
AW166_RS16295	COG1725	Transcriptional regulator
AW166_RS16305	COG0577	efflux transmembrane transporter activity
AW166_RS16305	COG1136	(ABC) transporter
AW166_RS16330	COG2207	Transcriptional regulator
AW166_RS16335	COG0456	acetyltransferase
AW166_RS16355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS16375	COG0642	Histidine kinase
AW166_RS16380	COG0745	RESPONSE REGULATOR receiver
AW166_RS16385	COG0596	Alpha beta hydrolase
AW166_RS16415	COG0730	response to heat
AW166_RS16425	COG0833	amino acid
AW166_RS16435	COG4335	DNA alkylation repair
AW166_RS16485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW166_RS16525	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW166_RS16530	COG1414	Transcriptional regulator
AW166_RS16545	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW166_RS16550	COG0640	Transcriptional regulator
AW166_RS16560	COG1960	acyl-CoA dehydrogenase activity
AW166_RS16580	COG3314	Sporulation integral membrane protein YlbJ
AW166_RS16595	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW166_RS16610	COG3848	Pyruvate phosphate dikinase
AW166_RS16610	COG0574	Belongs to the PEP-utilizing enzyme family
AW166_RS16615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS16630	COG5577	PFAM Coat F domain
AW166_RS16635	COG3403	YqcI/YcgG family
AW166_RS16640	COG1280	lysine exporter protein (LysE YggA)
AW166_RS16675	COG1063	alcohol dehydrogenase
AW166_RS16690	COG1027	Aspartate ammonia-lyase
AW166_RS16695	COG0252	asparaginase activity
AW166_RS16700	COG1396	sequence-specific DNA binding
AW166_RS16710	COG0322	excinuclease ABC activity
AW166_RS16715	COG0531	amino acid
AW166_RS16720	COG1114	Component of the transport system for branched-chain amino acids
AW166_RS16725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_RS16735	COG0281	malic enzyme
AW166_RS16760	COG0697	spore germination
AW166_RS16765	COG0784	Response regulator, receiver
AW166_RS16775	COG2066	Belongs to the glutaminase family
AW166_RS16805	COG0737	Belongs to the 5'-nucleotidase family
AW166_RS16810	COG0753	catalase activity
AW166_RS16815	COG2267	carboxylic ester hydrolase activity
AW166_RS16820	COG1335	isochorismatase
AW166_RS16840	COG0583	DNA-binding transcription factor activity
AW166_RS16885	COG0415	Belongs to the DNA photolyase family
AW166_RS16890	COG0288	reversible hydration of carbon dioxide
AW166_RS16900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW166_RS16905	COG5609	conserved protein (DUF2294)
AW166_RS16915	COG1575	Belongs to the MenA family. Type 1 subfamily
AW166_RS16920	COG2267	carboxylic ester hydrolase activity
AW166_RS16925	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW166_RS16930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW166_RS16935	COG1121	(ABC) transporter
AW166_RS16965	COG0798	PFAM Bile acid sodium symporter
AW166_RS16970	COG0346	lactoylglutathione lyase activity
AW166_RS16975	COG0640	Transcriptional regulator
AW166_RS16990	COG0443	Heat shock 70 kDa protein
AW166_RS17005	COG1522	sequence-specific DNA binding
AW166_RS17020	COG0346	lactoylglutathione lyase activity
AW166_RS17045	COG2169	Transcriptional regulator
AW166_RS17090	COG2814	Major facilitator Superfamily
AW166_RS17115	COG0745	RESPONSE REGULATOR receiver
AW166_RS17120	COG3850	Histidine kinase
AW166_RS17120	COG5002	protein histidine kinase activity
AW166_RS17150	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AW166_RS17175	COG1476	TRANSCRIPTIONal
AW166_RS17190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS17195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW166_RS17205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_RS17210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW166_RS17225	COG1136	(ABC) transporter
AW166_RS17230	COG0577	efflux transmembrane transporter activity
AW166_RS17250	COG3850	Histidine kinase
AW166_RS17250	COG5002	protein histidine kinase activity
AW166_RS17260	COG2364	Membrane
AW166_RS17265	COG1846	Transcriptional regulator
AW166_RS17275	COG2808	Putative FMN-binding domain
AW166_RS17280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS17285	COG2271	Major facilitator Superfamily
AW166_RS17290	COG1556	Lactate utilization protein
AW166_RS17295	COG1139	Iron-sulfur cluster binding protein
AW166_RS17305	COG0583	DNA-binding transcription factor activity
AW166_RS17315	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW166_RS17340	COG0738	Major facilitator superfamily
AW166_RS17345	COG0673	inositol 2-dehydrogenase activity
AW166_RS17350	COG0561	phosphatase activity
AW166_RS17360	COG1609	Transcriptional regulator
AW166_RS17365	COG0457	Tetratricopeptide repeat
AW166_RS17385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW166_RS17415	COG0534	Mate efflux family protein
AW166_RS17430	COG2814	Major facilitator Superfamily
AW166_RS17435	COG1309	transcriptional regulator
AW166_RS17450	COG0814	amino acid
AW166_RS17455	COG1760	l-serine dehydratase
AW166_RS17460	COG1760	l-serine dehydratase
AW166_RS17470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW166_RS17475	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AW166_RS17485	COG1335	isochorismatase
AW166_RS17490	COG1522	sequence-specific DNA binding
AW166_RS17495	COG0531	amino acid
AW166_RS17510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW166_RS17530	COG1595	DNA-templated transcription, initiation
AW166_RS17545	COG0662	Cupin 2, conserved barrel domain protein
AW166_RS17555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS17555	COG2207	Transcriptional regulator
AW166_RS17610	COG0477	Major facilitator Superfamily
AW166_RS17620	COG1846	Transcriptional regulator
AW166_RS17625	COG2814	Major facilitator Superfamily
AW166_RS17635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW166_RS17640	COG1131	(ABC) transporter
AW166_RS17660	COG2076	Multidrug Resistance protein
AW166_RS17665	COG1309	transcriptional regulator
AW166_RS17680	COG2031	fatty acid transporter
AW166_RS17690	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW166_RS17720	COG1122	ATPase activity
AW166_RS17725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW166_RS17740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AW166_RS17745	COG1288	antiporter activity
AW166_RS17750	COG2356	endonuclease I
AW166_RS17765	COG3620	sequence-specific DNA binding
AW166_RS17770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW166_RS17775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW166_RS17780	COG0124	histidyl-tRNA synthetase
AW166_RS17795	COG1733	regulation of RNA biosynthetic process
AW166_RS17800	COG0778	Nitroreductase
AW166_RS17820	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS17830	COG1131	(ABC) transporter
AW166_RS17855	COG1011	Hydrolase
AW166_RS17865	COG2365	Tyrosine phosphatase family
AW166_RS17890	COG0346	lactoylglutathione lyase activity
AW166_RS17895	COG1940	carbohydrate kinase activity
AW166_RS17900	COG0738	Major facilitator superfamily
AW166_RS17905	COG0110	maltose O-acetyltransferase activity
AW166_RS17920	COG0577	efflux transmembrane transporter activity
AW166_RS17920	COG1136	(ABC) transporter
AW166_RS17930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW166_RS17935	COG0628	permease
AW166_RS17955	COG2226	methyltransferase
AW166_RS17965	COG0477	Major facilitator Superfamily
AW166_RS17995	COG1253	flavin adenine dinucleotide binding
AW166_RS18000	COG0789	Transcriptional regulator
AW166_RS18005	COG0697	spore germination
AW166_RS18010	COG1357	PFAM Pentapeptide repeats (8 copies)
AW166_RS18015	COG3813	Protein conserved in bacteria
AW166_RS18020	COG2706	6-phosphogluconolactonase activity
AW166_RS18025	COG1070	Carbohydrate kinase
AW166_RS18035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW166_RS18040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AW166_RS18050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW166_RS18055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW166_RS18060	COG0604	alcohol dehydrogenase
AW166_RS18065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW166_RS18075	COG3321	synthase
AW166_RS18075	COG0604	alcohol dehydrogenase
AW166_RS18085	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS18110	COG0656	L-ascorbic acid biosynthetic process
AW166_RS18115	COG2814	Major facilitator Superfamily
AW166_RS18130	COG0346	lactoylglutathione lyase activity
AW166_RS18135	COG0814	amino acid
AW166_RS18160	COG1393	Belongs to the ArsC family
AW166_RS18170	COG1733	regulation of RNA biosynthetic process
AW166_RS18175	COG2188	Transcriptional regulator
AW166_RS18185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AW166_RS18190	COG1733	regulation of RNA biosynthetic process
AW166_RS18195	COG1733	regulation of RNA biosynthetic process
AW166_RS18210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS18230	COG0384	phenazine biosynthesis protein PhzF
AW166_RS18240	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS18250	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_RS18260	COG1733	regulation of RNA biosynthetic process
AW166_RS18295	COG1191	sigma factor activity
AW166_RS18310	COG1309	transcriptional regulator
AW166_RS18330	COG3152	Membrane
AW166_RS18355	COG1151	hydroxylamine reductase activity
AW166_RS18365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS18370	COG3757	hydrolase, family 25
AW166_RS18370	COG3409	Peptidoglycan-binding domain 1 protein
AW166_RS18405	COG2072	flavoprotein involved in K transport
AW166_RS18445	COG1113	amino acid transport
AW166_RS18450	COG2814	Major facilitator Superfamily
AW166_RS18485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW166_RS18490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW166_RS18510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS18520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS18525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS18530	COG3739	integral membrane protein
AW166_RS18535	COG0384	phenazine biosynthesis protein PhzF
AW166_RS18565	COG0583	DNA-binding transcription factor activity
AW166_RS18585	COG1193	negative regulation of DNA recombination
AW166_RS18600	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AW166_RS18605	COG1164	Oligoendopeptidase f
AW166_RS18610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW166_RS18640	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_RS18665	COG0640	Transcriptional regulator
AW166_RS18670	COG0604	alcohol dehydrogenase
AW166_RS18690	COG2808	Putative FMN-binding domain
AW166_RS18695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_RS18705	COG0385	Bile acid
AW166_RS18710	COG0277	FAD linked oxidase domain protein
AW166_RS18745	COG1216	Glycosyl transferase, family 2
AW166_RS18750	COG1024	Enoyl-CoA hydratase
AW166_RS18760	COG1285	pathogenesis
AW166_RS18770	COG2514	catechol 2,3-dioxygenase activity
AW166_RS18775	COG2720	vancomycin resistance protein
AW166_RS18815	COG0716	FMN binding
AW166_RS18845	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS18855	COG0165	Argininosuccinate lyase
AW166_RS18870	COG4145	pantothenate transmembrane transporter activity
AW166_RS18875	COG3924	membrane
AW166_RS18880	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS18885	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS18895	COG1657	PFAM Prenyltransferase squalene oxidase
AW166_RS18900	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW166_RS18905	COG2962	Rard protein
AW166_RS18910	COG3326	Membrane
AW166_RS18925	COG0489	protein tyrosine kinase activity
AW166_RS18935	COG0314	molybdopterin synthase activity
AW166_RS18940	COG0303	'Molybdopterin
AW166_RS18945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_RS18950	COG2116	formate transmembrane transporter activity
AW166_RS18960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW166_RS18965	COG5609	conserved protein (DUF2294)
AW166_RS18970	COG2427	Protein of unknown function (DUF1641)
AW166_RS18975	COG3383	formate dehydrogenase (NAD+) activity
AW166_RS18985	COG0697	spore germination
AW166_RS19025	COG2226	methyltransferase
AW166_RS19030	COG4166	transmembrane transport
AW166_RS19035	COG4166	transmembrane transport
AW166_RS19040	COG4166	transmembrane transport
AW166_RS19050	COG1316	TRANSCRIPTIONal
AW166_RS19060	COG1595	DNA-templated transcription, initiation
AW166_RS19085	COG1131	(ABC) transporter
AW166_RS19095	COG0673	inositol 2-dehydrogenase activity
AW166_RS19100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW166_RS19105	COG0187	DNA topoisomerase II activity
AW166_RS19115	COG1832	CoA-binding protein
AW166_RS19120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW166_RS19125	COG0745	RESPONSE REGULATOR receiver
AW166_RS19140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW166_RS19145	COG4841	protein insertion into membrane
AW166_RS19150	COG0824	Thioesterase
AW166_RS19180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_RS19190	COG2274	protein secretion by the type I secretion system
AW166_RS19195	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW166_RS19225	COG2211	Major facilitator Superfamily
AW166_RS19235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW166_RS19250	COG0183	Belongs to the thiolase family
AW166_RS19255	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_RS19260	COG1268	BioY protein
AW166_RS19265	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_RS19310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS19320	COG5002	protein histidine kinase activity
AW166_RS19325	COG0400	carboxylic ester hydrolase activity
AW166_RS19330	COG0346	lactoylglutathione lyase activity
AW166_RS19335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW166_RS19340	COG0069	glutamate synthase activity
AW166_RS19345	COG1902	pentaerythritol trinitrate reductase activity
AW166_RS19350	COG1329	Transcriptional regulator
AW166_RS19355	COG0010	Belongs to the arginase family
AW166_RS19380	COG2226	methyltransferase
AW166_RS19435	COG4846	Membrane protein involved in cytochrome C biogenesis
AW166_RS19440	COG0785	Cytochrome C biogenesis protein
AW166_RS19450	COG0583	DNA-binding transcription factor activity
AW166_RS19455	COG1380	Effector of murein hydrolase LrgA
AW166_RS19460	COG1346	cytolysis
AW166_RS19475	COG0730	response to heat
AW166_RS19485	COG3409	Peptidoglycan-binding domain 1 protein
AW166_RS19485	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW166_RS19500	COG1132	(ABC) transporter
AW166_RS19505	COG1132	(ABC) transporter
AW166_RS19540	COG3639	organic phosphonate transmembrane transporter activity
AW166_RS19545	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AW166_RS19560	COG0737	Belongs to the 5'-nucleotidase family
AW166_RS19570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW166_RS19590	COG1695	Transcriptional regulator
AW166_RS19625	COG3409	Peptidoglycan-binding domain 1 protein
AW166_RS19625	COG1388	LysM domain
AW166_RS19625	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW166_RS19630	COG4824	toxin secretion phage lysis holin
AW166_RS19795	COG1595	DNA-templated transcription, initiation
AW166_RS19840	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AW166_RS19920	COG1396	sequence-specific DNA binding
AW166_RS19945	COG0174	glutamine synthetase
AW166_RS19950	COG0789	Transcriptional regulator
AW166_RS19955	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW166_RS19965	COG2860	membrane
AW166_RS19970	COG0464	growth
AW166_RS20000	COG3584	3D domain protein
AW166_RS20000	COG1388	LysM domain
AW166_RS20005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW166_RS20005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW166_RS20005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW166_RS20010	COG1105	Belongs to the carbohydrate kinase PfkB family
AW166_RS20015	COG1349	DNA-binding transcription factor activity
AW166_RS20025	COG2322	membrane
AW166_RS20040	COG1113	amino acid transport
AW166_RS20050	COG1408	metallophosphoesterase
AW166_RS20055	COG2116	formate transmembrane transporter activity
AW166_RS20065	COG2217	Heavy metal translocating P-type atpase
AW166_RS20070	COG2608	mercury ion transmembrane transporter activity
AW166_RS20075	COG1937	Protein conserved in bacteria
AW166_RS20085	COG2819	hydrolase of the alpha beta superfamily
AW166_RS20090	COG1120	ATPase activity
AW166_RS20095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS20100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS20105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS20115	COG0708	Exodeoxyribonuclease III
AW166_RS20120	COG2169	Transcriptional regulator
AW166_RS20125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW166_RS20130	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW166_RS20140	COG2364	Membrane
AW166_RS20155	COG2267	carboxylic ester hydrolase activity
AW166_RS20160	COG0346	lactoylglutathione lyase activity
AW166_RS20165	COG3300	MHYT domain
AW166_RS20165	COG5001	Diguanylate cyclase
AW166_RS20185	COG1346	cytolysis
AW166_RS20190	COG1380	Effector of murein hydrolase LrgA
AW166_RS20195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW166_RS20200	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_RS20200	COG0596	Alpha beta hydrolase
AW166_RS20205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW166_RS20220	COG1404	Belongs to the peptidase S8 family
AW166_RS20225	COG3773	Cell wall hydrolase
AW166_RS20230	COG0562	UDP-galactopyranose mutase
AW166_RS20235	COG1368	sulfuric ester hydrolase activity
AW166_RS20240	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW166_RS20250	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW166_RS20275	COG1131	(ABC) transporter
AW166_RS20295	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW166_RS20300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW166_RS20305	COG1013	pyruvate-flavodoxin oxidoreductase activity
AW166_RS20310	COG0674	pyruvate-flavodoxin oxidoreductase activity
AW166_RS20310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AW166_RS20320	COG2359	stage V sporulation protein S
AW166_RS20325	COG1692	metallophosphoesterase
AW166_RS20350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW166_RS20355	COG1426	Protein conserved in bacteria
AW166_RS20370	COG0300	oxidoreductase activity
AW166_RS20375	COG0612	Peptidase, M16
AW166_RS20380	COG0612	Peptidase, M16
AW166_RS20390	COG4603	Belongs to the binding-protein-dependent transport system permease family
AW166_RS20395	COG4603	Belongs to the binding-protein-dependent transport system permease family
AW166_RS20400	COG3845	ABC transporter
AW166_RS20405	COG1744	ABC transporter substrate-binding protein PnrA-like
AW166_RS20410	COG2188	Transcriptional regulator
AW166_RS20415	COG1674	ftsk spoiiie
AW166_RS20425	COG0740	serine-type endopeptidase activity
AW166_RS20430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW166_RS20445	COG0527	aspartate kinase activity
AW166_RS20450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW166_RS20455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW166_RS20460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW166_RS20465	COG1873	PFAM PRC-barrel domain
AW166_RS20470	COG0612	Peptidase, M16
AW166_RS20475	COG0726	polysaccharide deacetylase
AW166_RS20490	COG0196	riboflavin kinase activity
AW166_RS20495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW166_RS20505	COG1550	Protein conserved in bacteria
AW166_RS20515	COG1358	cellular component organization or biogenesis
AW166_RS20520	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW166_RS20525	COG0195	Participates in both transcription termination and antitermination
AW166_RS20545	COG0750	zinc metalloprotease
AW166_RS20555	COG4589	Belongs to the CDS family
AW166_RS20560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW166_RS20570	COG0528	UMP kinase activity
AW166_RS20600	COG4974	Belongs to the 'phage' integrase family
AW166_RS20610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW166_RS20620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW166_RS20660	COG1837	Belongs to the UPF0109 family
AW166_RS20670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW166_RS20680	COG0552	protein localization to endoplasmic reticulum
AW166_RS20685	COG1196	nuclear chromosome segregation
AW166_RS20695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW166_RS20700	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS20705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW166_RS20720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW166_RS20725	COG1461	Dihydroxyacetone kinase
AW166_RS20730	COG1302	Protein conserved in bacteria
AW166_RS20745	COG1564	THIamine pyrophosphokinase
AW166_RS20750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW166_RS20755	COG1162	GTPase activity
AW166_RS20760	COG2815	serine threonine protein kinase
AW166_RS20760	COG0515	serine threonine protein kinase
AW166_RS20765	COG0631	protein serine/threonine phosphatase activity
AW166_RS20775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW166_RS20775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW166_RS20785	COG0242	peptide deformylase activity
AW166_RS20790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW166_RS20795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW166_RS20815	COG1561	YicC-like family, N-terminal region
AW166_RS20820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW166_RS20830	COG0006	proline dipeptidase activity
AW166_RS20845	COG3069	C4-dicarboxylate transmembrane transporter activity
AW166_RS20910	COG0564	pseudouridine synthase activity
AW166_RS20930	COG3599	regulation of cell shape
AW166_RS20935	COG2302	S4 RNA-binding domain
AW166_RS20940	COG0762	integral membrane protein
AW166_RS20950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW166_RS20955	COG1496	oxidoreductase activity
AW166_RS20960	COG1873	PFAM PRC-barrel domain
AW166_RS20965	COG1191	sigma factor activity
AW166_RS20970	COG1191	sigma factor activity
AW166_RS20980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW166_RS20985	COG0849	cell division
AW166_RS20990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW166_RS20995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW166_RS21005	COG0772	Belongs to the SEDS family
AW166_RS21020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW166_RS21025	COG0768	penicillin binding
AW166_RS21030	COG0768	penicillin binding
AW166_RS21035	COG4839	cell division protein FtsL
AW166_RS21050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW166_RS21065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AW166_RS21070	COG1399	metal-binding, possibly nucleic acid-binding protein
AW166_RS21120	COG4824	toxin secretion phage lysis holin
AW166_RS21215	COG4626	Terminase
AW166_RS21215	COG1802	Transcriptional regulator
AW166_RS21240	COG0582	viral genome integration into host DNA
AW166_RS21305	COG0756	dUTP diphosphatase activity
AW166_RS21315	COG1191	sigma factor activity
AW166_RS21340	COG1484	DNA-dependent DNA replication
AW166_RS21370	COG1396	sequence-specific DNA binding
AW166_RS21380	COG1396	sequence-specific DNA binding
AW166_RS21395	COG0582	viral genome integration into host DNA
AW166_RS21405	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW166_RS21410	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW166_RS21415	COG3314	Sporulation integral membrane protein YlbJ
AW166_RS21425	COG0742	ribosomal rna small subunit methyltransferase
AW166_RS21440	COG3679	Belongs to the UPF0342 family
AW166_RS21445	COG0406	alpha-ribazole phosphatase activity
AW166_RS21460	COG2340	Cysteine-rich secretory protein family
AW166_RS21475	COG3336	cytochrome c oxidase
AW166_RS21510	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW166_RS21515	COG0772	Belongs to the SEDS family
AW166_RS21525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW166_RS21530	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW166_RS21540	COG4896	Protein conserved in bacteria
AW166_RS21555	COG1217	gtp-binding protein TYPA
AW166_RS21565	COG0483	inositol monophosphate 1-phosphatase activity
AW166_RS21585	COG1982	Orn Lys Arg decarboxylase major
AW166_RS21630	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_RS21635	COG0022	dehydrogenase e1 component
AW166_RS21640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW166_RS21650	COG0242	peptide deformylase activity
AW166_RS21655	COG0561	phosphatase activity
AW166_RS21665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW166_RS21670	COG0569	domain protein
AW166_RS21690	COG0583	DNA-binding transcription factor activity
AW166_RS21695	COG0517	IMP dehydrogenase activity
AW166_RS21705	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW166_RS21715	COG4703	Protein of unknown function (DUF1797)
AW166_RS21730	COG2200	EAL domain
AW166_RS21735	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS21740	COG1408	metallophosphoesterase
AW166_RS21750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AW166_RS21790	COG2814	Major facilitator Superfamily
AW166_RS21810	COG3209	COG3209 Rhs family protein
AW166_RS21820	COG2205	protein histidine kinase activity
AW166_RS21830	COG0436	Aminotransferase
AW166_RS21835	COG1609	Transcriptional regulator
AW166_RS21840	COG3833	ABC-type maltose transport systems, permease component
AW166_RS21845	COG1175	transmembrane transport
AW166_RS21850	COG2182	Extracellular solute-binding protein
AW166_RS21860	COG0366	Alpha amylase catalytic
AW166_RS21865	COG3842	ATPase activity
AW166_RS21905	COG0183	Belongs to the thiolase family
AW166_RS21945	COG1695	Transcriptional regulator
AW166_RS21950	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS21960	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AW166_RS21970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW166_RS21975	COG0436	Aminotransferase
AW166_RS21995	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW166_RS22015	COG2199	diguanylate cyclase activity
AW166_RS22020	COG0778	Nitroreductase
AW166_RS22045	COG2190	(PTS) system
AW166_RS22045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW166_RS22045	COG1263	PTS System
AW166_RS22050	COG3711	transcriptional antiterminator
AW166_RS22060	COG2188	Transcriptional regulator
AW166_RS22070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW166_RS22100	COG1547	Domain of unknown function (DUF309)
AW166_RS22105	COG0456	acetyltransferase
AW166_RS22115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW166_RS22120	COG4086	secreted protein
AW166_RS22125	COG0561	phosphatase activity
AW166_RS22130	COG0697	spore germination
AW166_RS22145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_RS22170	COG0733	neurotransmitter:sodium symporter activity
AW166_RS22190	COG1686	Belongs to the peptidase S11 family
AW166_RS22195	COG1725	Transcriptional regulator
AW166_RS22200	COG1131	(ABC) transporter
AW166_RS22220	COG1846	Transcriptional regulator
AW166_RS22235	COG0598	Magnesium transport protein CorA
AW166_RS22260	COG4974	Belongs to the 'phage' integrase family
AW166_RS22270	COG0735	belongs to the Fur family
AW166_RS22275	COG1300	Membrane
AW166_RS22295	COG0667	Aldo Keto reductase
AW166_RS22300	COG0656	L-ascorbic acid biosynthetic process
AW166_RS22305	COG0456	acetyltransferase
AW166_RS22305	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW166_RS22315	COG0737	Belongs to the 5'-nucleotidase family
AW166_RS22315	COG1525	nuclease
AW166_RS22315	COG4085	toxin activity
AW166_RS22325	COG0596	Alpha beta hydrolase
AW166_RS22330	COG2056	Na+-H+ antiporter family
AW166_RS22335	COG1609	Transcriptional regulator
AW166_RS22340	COG0456	acetyltransferase
AW166_RS22345	COG1073	alpha beta
AW166_RS22360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW166_RS22360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW166_RS22365	COG0307	riboflavin synthase, alpha
AW166_RS22390	COG4106	trans-aconitate 2-methyltransferase activity
AW166_RS22395	COG1073	alpha beta
AW166_RS22395	COG2226	methyltransferase
AW166_RS22410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW166_RS22420	COG1757	Na H antiporter
AW166_RS22425	COG0737	Belongs to the 5'-nucleotidase family
AW166_RS22435	COG1522	sequence-specific DNA binding
AW166_RS22455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW166_RS22465	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AW166_RS22480	COG0300	oxidoreductase activity
AW166_RS22485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS22495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_RS22500	COG1760	l-serine dehydratase
AW166_RS22505	COG1760	l-serine dehydratase
AW166_RS22525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW166_RS22535	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW166_RS22540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS22555	COG1376	ErfK ybiS ycfS ynhG family protein
AW166_RS22560	COG4129	membrane
AW166_RS22565	COG1126	abc transporter atp-binding protein
AW166_RS22570	COG0765	amino acid transport
AW166_RS22575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW166_RS22595	COG0772	Belongs to the SEDS family
AW166_RS22605	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW166_RS22610	COG0022	dehydrogenase e1 component
AW166_RS22615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW166_RS22620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW166_RS22635	COG0280	phosphate acetyltransferase
AW166_RS22645	COG3829	transcription factor binding
AW166_RS22645	COG3290	protein histidine kinase activity
AW166_RS22655	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_RS22660	COG3093	addiction module antidote protein HigA
AW166_RS22670	COG0745	RESPONSE REGULATOR receiver
AW166_RS22680	COG0750	zinc metalloprotease
AW166_RS22685	COG0497	DNA recombination
AW166_RS22695	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW166_RS22705	COG0142	geranyltranstransferase activity
AW166_RS22730	COG1302	Protein conserved in bacteria
AW166_RS22735	COG0439	Biotin carboxylase
AW166_RS22740	COG0511	ligase activity, forming carbon-carbon bonds
AW166_RS22785	COG3854	ATPases associated with a variety of cellular activities
AW166_RS22810	COG0006	proline dipeptidase activity
AW166_RS22825	COG3872	metal-dependent enzyme
AW166_RS22835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW166_RS22855	COG0095	Lipoate-protein ligase
AW166_RS22860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_RS22865	COG1609	Transcriptional regulator
AW166_RS22875	COG2076	Multidrug Resistance protein
AW166_RS22880	COG2076	Multidrug Resistance protein
AW166_RS22920	COG1131	(ABC) transporter
AW166_RS22925	COG1725	Transcriptional regulator
AW166_RS22955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW166_RS23010	COG4970	Tfp pilus assembly protein FimT
AW166_RS23020	COG1459	type II secretion system
AW166_RS23025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW166_RS23075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW166_RS23080	COG1410	methionine synthase
AW166_RS23080	COG0646	methionine synthase
AW166_RS23085	COG0646	methionine synthase
AW166_RS23085	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW166_RS23090	COG0626	cystathionine gamma-synthase activity
AW166_RS23095	COG0626	cystathionine gamma-synthase activity
AW166_RS23120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS23130	COG1940	carbohydrate kinase activity
AW166_RS23135	COG4483	Protein conserved in bacteria
AW166_RS23140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW166_RS23145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AW166_RS23150	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW166_RS23155	COG0704	Plays a role in the regulation of phosphate uptake
AW166_RS23165	COG0581	inorganic phosphate transmembrane transporter activity
AW166_RS23170	COG0573	inorganic phosphate transmembrane transporter activity
AW166_RS23175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW166_RS23180	COG0768	penicillin binding
AW166_RS23185	COG0477	Major facilitator Superfamily
AW166_RS23190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW166_RS23215	COG0735	belongs to the Fur family
AW166_RS23220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW166_RS23225	COG1121	(ABC) transporter
AW166_RS23230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS23260	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW166_RS23265	COG2384	SAM-dependent methyltransferase
AW166_RS23270	COG2010	Cytochrome c
AW166_RS23275	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AW166_RS23280	COG0358	DNA primase activity
AW166_RS23300	COG0517	IMP dehydrogenase activity
AW166_RS23315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW166_RS23320	COG0295	cytidine deaminase activity
AW166_RS23325	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW166_RS23335	COG1480	7TM receptor with intracellular HD hydrolase
AW166_RS23340	COG1702	phosphate starvation-inducible protein PhoH
AW166_RS23360	COG1610	YqeY-like protein
AW166_RS23365	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AW166_RS23370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW166_RS23375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW166_RS23405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW166_RS23410	COG1733	regulation of RNA biosynthetic process
AW166_RS23435	COG1466	dna polymerase III delta subunit
AW166_RS23445	COG0658	competence protein
AW166_RS23445	COG2333	competence protein COMEC
AW166_RS23450	COG2131	deaminase
AW166_RS23455	COG1596	polysaccharide export
AW166_RS23455	COG1555	photosystem II stabilization
AW166_RS23460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW166_RS23465	COG2226	methyltransferase
AW166_RS23470	COG0799	negative regulation of ribosome biogenesis
AW166_RS23475	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW166_RS23485	COG1534	Rna-binding protein
AW166_RS23495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW166_RS23500	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW166_RS23525	COG1595	DNA-templated transcription, initiation
AW166_RS23535	COG0778	Nitroreductase
AW166_RS23540	COG2357	RelA SpoT domain protein
AW166_RS23550	COG1785	Belongs to the alkaline phosphatase family
AW166_RS23560	COG2267	carboxylic ester hydrolase activity
AW166_RS23595	COG1404	Belongs to the peptidase S8 family
AW166_RS23600	COG3186	Phenylalanine-4-hydroxylase
AW166_RS23610	COG2514	catechol 2,3-dioxygenase activity
AW166_RS23615	COG2514	catechol 2,3-dioxygenase activity
AW166_RS23620	COG2259	Doxx family
AW166_RS23660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS23670	COG1012	belongs to the aldehyde dehydrogenase family
AW166_RS23670	COG1454	alcohol dehydrogenase
AW166_RS23675	COG0626	cystathionine gamma-synthase activity
AW166_RS23680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW166_RS23705	COG0768	penicillin binding
AW166_RS23720	COG0826	peptidase U32
AW166_RS23725	COG0826	peptidase U32
AW166_RS23730	COG4122	O-methyltransferase activity
AW166_RS23735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW166_RS23755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW166_RS23765	COG0628	permease
AW166_RS23785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW166_RS23795	COG0482	sulfurtransferase activity
AW166_RS23800	COG1104	cysteine desulfurase activity
AW166_RS23805	COG1959	2 iron, 2 sulfur cluster binding
AW166_RS23810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AW166_RS23820	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW166_RS23845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW166_RS23855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW166_RS23855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW166_RS23860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW166_RS23865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW166_RS23865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW166_RS23875	COG2244	polysaccharide biosynthetic process
AW166_RS23880	COG2323	membrane
AW166_RS23890	COG1862	Preprotein translocase
AW166_RS23920	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW166_RS23930	COG0697	spore germination
AW166_RS23935	COG0697	spore germination
AW166_RS23940	COG0640	Transcriptional regulator
AW166_RS23965	COG0157	Belongs to the NadC ModD family
AW166_RS23970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW166_RS23975	COG1104	cysteine desulfurase activity
AW166_RS23980	COG1827	regulation of RNA biosynthetic process
AW166_RS23985	COG2258	MOSC domain
AW166_RS23990	COG0077	Prephenate dehydratase
AW166_RS23995	COG0577	efflux transmembrane transporter activity
AW166_RS24000	COG0577	efflux transmembrane transporter activity
AW166_RS24005	COG1136	(ABC) transporter
AW166_RS24010	COG5002	protein histidine kinase activity
AW166_RS24020	COG0745	RESPONSE REGULATOR receiver
AW166_RS24025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW166_RS24030	COG3290	protein histidine kinase activity
AW166_RS24040	COG2868	ribosomal protein
AW166_RS24050	COG1530	ribonuclease E activity
AW166_RS24055	COG1994	Peptidase M50
AW166_RS24060	COG0739	heme binding
AW166_RS24065	COG2894	cell division
AW166_RS24085	COG1077	Cell shape determining protein MreB Mrl
AW166_RS24105	COG0285	dihydrofolate synthase activity
AW166_RS24110	COG0525	valine-tRNA ligase activity
AW166_RS24120	COG1388	LysM domain
AW166_RS24130	COG0113	porphobilinogen synthase activity
AW166_RS24135	COG1587	Uroporphyrinogen-III synthase
AW166_RS24145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW166_RS24155	COG1846	Transcriptional regulator
AW166_RS24160	COG1764	response to oxidative stress
AW166_RS24175	COG0470	DNA polymerase III
AW166_RS24175	COG1067	ATP-dependent peptidase activity
AW166_RS24230	COG0622	Phosphoesterase
AW166_RS24245	COG5401	PFAM Sporulation and spore germination
AW166_RS24265	COG1309	transcriptional regulator
AW166_RS24280	COG2197	response regulator
AW166_RS24285	COG2233	PERMEase
AW166_RS24295	COG0402	S-adenosylhomocysteine deaminase activity
AW166_RS24300	COG0402	S-adenosylhomocysteine deaminase activity
AW166_RS24310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW166_RS24320	COG0444	Belongs to the ABC transporter superfamily
AW166_RS24325	COG4608	Belongs to the ABC transporter superfamily
AW166_RS24330	COG3275	phosphorelay sensor kinase activity
AW166_RS24335	COG3279	Response regulator of the LytR AlgR family
AW166_RS24350	COG1983	PspC domain protein
AW166_RS24355	COG1396	sequence-specific DNA binding
AW166_RS24360	COG0697	spore germination
AW166_RS24370	COG1959	2 iron, 2 sulfur cluster binding
AW166_RS24375	COG1668	transmembrane transport
AW166_RS24380	COG4152	abc transporter atp-binding protein
AW166_RS24385	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AW166_RS24395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW166_RS24400	COG1876	peptidase activity
AW166_RS24405	COG0824	Thioesterase
AW166_RS24410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW166_RS24415	COG1053	succinate dehydrogenase
AW166_RS24420	COG2009	succinate dehydrogenase
AW166_RS24425	COG1719	4-vinyl reductase, 4VR
AW166_RS24435	COG3118	belongs to the thioredoxin family
AW166_RS24440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW166_RS24445	COG2086	electron transfer activity
AW166_RS24450	COG1024	Enoyl-CoA hydratase
AW166_RS24455	COG1309	transcriptional regulator
AW166_RS24460	COG0318	PFAM AMP-dependent synthetase and ligase
AW166_RS24480	COG2318	DinB family
AW166_RS24510	COG1131	(ABC) transporter
AW166_RS24515	COG2205	protein histidine kinase activity
AW166_RS24520	COG0745	RESPONSE REGULATOR receiver
AW166_RS24530	COG4895	conserved protein (DUF2196)
AW166_RS24535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW166_RS24550	COG4509	Sortase family
AW166_RS24555	COG1120	ATPase activity
AW166_RS24570	COG5386	Cell surface protein
AW166_RS24580	COG5386	Cell surface protein
AW166_RS24585	COG1114	Component of the transport system for branched-chain amino acids
AW166_RS24590	COG1187	pseudouridine synthase activity
AW166_RS24605	COG1796	DNA polymerase
AW166_RS24605	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW166_RS24610	COG1286	toxin biosynthetic process
AW166_RS24655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW166_RS24665	COG1418	mRNA catabolic process
AW166_RS24690	COG2814	Major facilitator Superfamily
AW166_RS24695	COG1566	PFAM secretion protein HlyD family protein
AW166_RS24700	COG1309	transcriptional regulator
AW166_RS24705	COG1363	Peptidase, m42
AW166_RS24730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW166_RS24740	COG1484	DNA-dependent DNA replication
AW166_RS24745	COG3611	Membrane attachment protein
AW166_RS24755	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW166_RS24760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW166_RS24765	COG0237	dephospho-CoA kinase activity
AW166_RS24770	COG1971	Probably functions as a manganese efflux pump
AW166_RS24780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW166_RS24780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW166_RS24785	COG5002	protein histidine kinase activity
AW166_RS24790	COG0745	RESPONSE REGULATOR receiver
AW166_RS24810	COG0538	isocitrate dehydrogenase activity
AW166_RS24815	COG0372	Belongs to the citrate synthase family
AW166_RS24830	COG0628	permease
AW166_RS24835	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW166_RS24860	COG1725	Transcriptional regulator
AW166_RS24865	COG0281	malic enzyme
AW166_RS24870	COG0587	DNA-directed DNA polymerase activity
AW166_RS24885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW166_RS24905	COG4109	DRTGG domain
AW166_RS24920	COG0006	proline dipeptidase activity
AW166_RS24955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS24960	COG0662	Cupin 2, conserved barrel domain protein
AW166_RS24970	COG1476	TRANSCRIPTIONal
AW166_RS24985	COG1028	Short-chain dehydrogenase reductase Sdr
AW166_RS24990	COG0589	response to stress
AW166_RS25030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS25050	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW166_RS25055	COG0827	DNA restriction-modification system
AW166_RS25060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW166_RS25065	COG3874	Sporulation protein YtfJ
AW166_RS25080	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW166_RS25090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW166_RS25105	COG1104	cysteine desulfurase activity
AW166_RS25115	COG0583	DNA-binding transcription factor activity
AW166_RS25120	COG0697	spore germination
AW166_RS25130	COG1956	GAF domain-containing protein
AW166_RS25135	COG0626	cystathionine gamma-synthase activity
AW166_RS25165	COG1595	DNA-templated transcription, initiation
AW166_RS25175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW166_RS25180	COG0454	-acetyltransferase
AW166_RS25185	COG0517	IMP dehydrogenase activity
AW166_RS25190	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW166_RS25200	COG0745	RESPONSE REGULATOR receiver
AW166_RS25210	COG0666	response to abiotic stimulus
AW166_RS25245	COG1609	Transcriptional regulator
AW166_RS25255	COG4851	CamS sex pheromone cAM373 precursor
AW166_RS25260	COG3118	belongs to the thioredoxin family
AW166_RS25270	COG2309	aminopeptidase activity
AW166_RS25290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS25305	COG1674	ftsk spoiiie
AW166_RS25315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW166_RS25320	COG4848	Belongs to the UPF0354 family
AW166_RS25325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_RS25330	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AW166_RS25335	COG1363	Peptidase, m42
AW166_RS25345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS25360	COG0510	thiamine kinase activity
AW166_RS25365	COG1523	belongs to the glycosyl hydrolase 13 family
AW166_RS25380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_RS25385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW166_RS25390	COG1349	DNA-binding transcription factor activity
AW166_RS25395	COG1187	pseudouridine synthase activity
AW166_RS25400	COG2244	polysaccharide biosynthetic process
AW166_RS25405	COG2081	HI0933 family
AW166_RS25410	COG2814	Major facilitator Superfamily
AW166_RS25420	COG3832	glyoxalase III activity
AW166_RS25440	COG1329	Transcriptional regulator
AW166_RS25450	COG4975	Glucose uptake
AW166_RS25465	COG0314	molybdopterin synthase activity
AW166_RS25470	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW166_RS25475	COG0303	'Molybdopterin
AW166_RS25485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW166_RS25510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW166_RS25520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AW166_RS25565	COG2814	Major facilitator Superfamily
AW166_RS25570	COG0475	glutathione-regulated potassium exporter activity
AW166_RS25575	COG0490	domain, Protein
AW166_RS25580	COG0582	viral genome integration into host DNA
AW166_RS25590	COG1136	(ABC) transporter
AW166_RS25610	COG1242	4 iron, 4 sulfur cluster binding
AW166_RS25615	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW166_RS25620	COG1131	(ABC) transporter
AW166_RS25630	COG1794	racemase activity, acting on amino acids and derivatives
AW166_RS25650	COG2267	carboxylic ester hydrolase activity
AW166_RS25655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW166_RS25660	COG0671	phosphoesterase, PA-phosphatase related
AW166_RS25665	COG0438	transferase activity, transferring glycosyl groups
AW166_RS25675	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW166_RS25730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW166_RS25735	COG5002	protein histidine kinase activity
AW166_RS25740	COG4191	Histidine kinase
AW166_RS25745	COG2267	carboxylic ester hydrolase activity
AW166_RS25765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW166_RS25770	COG1116	anion transmembrane transporter activity
AW166_RS25775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW166_RS25800	COG0494	nUDIX hydrolase
AW166_RS25830	COG0288	reversible hydration of carbon dioxide
AW166_RS25835	COG1271	oxidase subunit
AW166_RS25840	COG1294	oxidase, subunit
AW166_RS25860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS25885	COG1842	Phage shock protein A
AW166_RS25920	COG5002	protein histidine kinase activity
AW166_RS25925	COG0745	RESPONSE REGULATOR receiver
AW166_RS25955	COG1597	lipid kinase activity
AW166_RS25990	COG0586	Pfam SNARE associated Golgi protein
AW166_RS26000	COG0577	efflux transmembrane transporter activity
AW166_RS26005	COG1136	(ABC) transporter
AW166_RS26010	COG3708	Transcriptional regulator
AW166_RS26010	COG2207	Transcriptional regulator
AW166_RS26015	COG0745	RESPONSE REGULATOR receiver
AW166_RS26020	COG2205	protein histidine kinase activity
AW166_RS26025	COG0577	efflux transmembrane transporter activity
AW166_RS26035	COG0577	efflux transmembrane transporter activity
AW166_RS26040	COG1136	(ABC) transporter
AW166_RS26060	COG2188	Transcriptional regulator
AW166_RS26080	COG3964	amidohydrolase
AW166_RS26110	COG4948	Mandelate Racemase Muconate Lactonizing
AW166_RS26120	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW166_RS26125	COG0596	Alpha beta hydrolase
AW166_RS26130	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW166_RS26135	COG1169	isochorismate synthase
AW166_RS26140	COG1575	Belongs to the MenA family. Type 1 subfamily
AW166_RS26145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW166_RS26170	COG0058	SHG alpha-glucan phosphorylase activity
AW166_RS26175	COG0297	glycogen (starch) synthase activity
AW166_RS26180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW166_RS26290	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW166_RS26325	COG1285	pathogenesis
AW166_RS26330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW166_RS26340	COG0166	Belongs to the GPI family
AW166_RS26350	COG2155	Conserved Protein
AW166_RS26355	COG1098	S1 RNA binding domain
AW166_RS26360	COG0436	Aminotransferase
AW166_RS26365	COG1522	sequence-specific DNA binding
AW166_RS26370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW166_RS26375	COG2267	carboxylic ester hydrolase activity
AW166_RS26385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW166_RS26405	COG5018	Exonuclease
AW166_RS26410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW166_RS26430	COG2050	protein possibly involved in aromatic compounds catabolism
AW166_RS26440	COG1268	BioY protein
AW166_RS26450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW166_RS26455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW166_RS26470	COG3584	3D domain protein
AW166_RS26485	COG1252	NADH dehydrogenase
AW166_RS26500	COG3708	Transcriptional regulator
AW166_RS26515	COG1683	Conserved Protein
AW166_RS26535	COG0316	Belongs to the HesB IscA family
AW166_RS26550	COG1252	NADH dehydrogenase
AW166_RS26565	COG0390	transport system, permease component
AW166_RS26570	COG2824	Alkylphosphonate utilization operon protein PhnA
AW166_RS26610	COG4837	Protein of unknown function (DUF1462)
AW166_RS26615	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW166_RS26625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW166_RS26630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW166_RS26645	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW166_RS26650	COG0647	UMP catabolic process
AW166_RS26660	COG2445	Protein of unknown function DUF86
AW166_RS26665	COG1494	fructose-1,6-bisphosphatase
AW166_RS26685	COG4470	Protein conserved in bacteria
AW166_RS26695	COG0789	Transcriptional regulator
AW166_RS26700	COG4377	Putative membrane peptidase family (DUF2324)
AW166_RS26725	COG0739	heme binding
AW166_RS26735	COG3377	Domain of unknown function (DUF1805)
AW166_RS26740	COG0737	Belongs to the 5'-nucleotidase family
AW166_RS26750	COG1695	Transcriptional regulator
AW166_RS26765	COG0719	Fe-S assembly protein
AW166_RS26770	COG0822	iron-sulfur transferase activity
AW166_RS26775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW166_RS26780	COG0719	Fe-S assembly protein
AW166_RS26785	COG0396	ATPase activity
AW166_RS26790	COG1464	Belongs to the NlpA lipoprotein family
AW166_RS26795	COG1464	Belongs to the NlpA lipoprotein family
AW166_RS26800	COG2011	ABC-type metal ion transport system permease component
AW166_RS26805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW166_RS26820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW166_RS26825	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW166_RS26835	COG1393	Belongs to the ArsC family
AW166_RS26885	COG0039	L-malate dehydrogenase activity
AW166_RS26905	COG1309	transcriptional regulator
AW166_RS26910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW166_RS26915	COG1960	acyl-CoA dehydrogenase activity
AW166_RS26920	COG0183	Belongs to the thiolase family
AW166_RS26925	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW166_RS26925	COG1024	Enoyl-CoA hydratase
AW166_RS26935	COG1686	Belongs to the peptidase S11 family
AW166_RS26950	COG0011	TIGRFAM Protein of
AW166_RS26955	COG0840	transmembrane signaling receptor activity
AW166_RS26975	COG2814	Major facilitator Superfamily
AW166_RS26980	COG0531	amino acid
AW166_RS26990	COG0706	membrane insertase activity
AW166_RS27000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW166_RS27035	COG0586	Pfam SNARE associated Golgi protein
AW166_RS27045	COG1376	ErfK ybiS ycfS ynhG family protein
AW166_RS27050	COG0745	RESPONSE REGULATOR receiver
AW166_RS27055	COG5002	protein histidine kinase activity
AW166_RS27080	COG2151	metal-sulfur cluster biosynthetic enzyme
AW166_RS27085	COG3227	Zinc metalloprotease (Elastase)
AW166_RS27090	COG1741	Belongs to the pirin family
AW166_RS27105	COG0475	glutathione-regulated potassium exporter activity
AW166_RS27110	COG0490	domain, Protein
AW166_RS27120	COG1115	amino acid carrier protein
AW166_RS27125	COG0783	Belongs to the Dps family
AW166_RS27140	COG1611	Belongs to the LOG family
AW166_RS27155	COG2311	Membrane
AW166_RS27165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS27170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS27175	COG1115	amino acid carrier protein
AW166_RS27180	COG1115	amino acid carrier protein
AW166_RS27185	COG2910	NAD(P)H-binding
AW166_RS27200	COG0656	L-ascorbic acid biosynthetic process
AW166_RS27205	COG2814	Major facilitator Superfamily
AW166_RS27210	COG1733	regulation of RNA biosynthetic process
AW166_RS27220	COG1252	NADH dehydrogenase
AW166_RS27225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW166_RS27230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW166_RS27240	COG0840	transmembrane signaling receptor activity
AW166_RS27240	COG3290	protein histidine kinase activity
AW166_RS27250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW166_RS27255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW166_RS27270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW166_RS27325	COG0557	exoribonuclease II activity
AW166_RS27330	COG1647	Serine aminopeptidase, S33
AW166_RS27335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW166_RS27340	COG1346	cytolysis
AW166_RS27440	COG4695	Portal protein
AW166_RS27465	COG4974	Belongs to the 'phage' integrase family
AW166_RS27475	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW166_RS27480	COG0149	triose-phosphate isomerase activity
AW166_RS27490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW166_RS27505	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW166_RS27530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW166_RS27545	COG2323	membrane
AW166_RS27550	COG0740	serine-type endopeptidase activity
AW166_RS27555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW166_RS27565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW166_RS27575	COG1051	belongs to the nudix hydrolase family
AW166_RS27585	COG0492	ferredoxin-NADP+ reductase activity
AW166_RS27590	COG0457	Tetratricopeptide repeat
AW166_RS27595	COG0110	maltose O-acetyltransferase activity
AW166_RS27615	COG1950	PFAM Membrane protein of
AW166_RS27625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW166_RS27630	COG0556	nucleotide-excision repair
AW166_RS27650	COG0789	Transcriptional regulator
AW166_RS27675	COG2855	membrane
AW166_RS27680	COG0583	DNA-binding transcription factor activity
AW166_RS27690	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW166_RS27695	COG0488	(ABC) transporter
AW166_RS27705	COG1132	(ABC) transporter
AW166_RS27710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW166_RS27715	COG0793	Belongs to the peptidase S41A family
AW166_RS27715	COG3409	Peptidoglycan-binding domain 1 protein
AW166_RS27720	COG2177	Part of the ABC transporter FtsEX involved in
AW166_RS27725	COG2884	Cell division ATP-binding protein ftsE
AW166_RS27740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AW166_RS27745	COG0653	protein targeting
AW166_RS27750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW166_RS27755	COG1278	Cold shock
AW166_RS27760	COG1040	competence protein
AW166_RS27765	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW166_RS27770	COG0791	NLP P60 protein
AW166_RS27770	COG1388	LysM domain
AW166_RS27775	COG1733	regulation of RNA biosynthetic process
AW166_RS27785	COG1307	EDD domain protein, DegV family
AW166_RS27790	COG1739	Uncharacterized protein family UPF0029
AW166_RS27795	COG1316	TRANSCRIPTIONal
AW166_RS27800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW166_RS27805	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW166_RS27810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW166_RS27820	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW166_RS27820	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW166_RS27835	COG3394	polysaccharide catabolic process
AW166_RS27840	COG1486	melibiose metabolic process
AW166_RS27845	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW166_RS27850	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW166_RS27860	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW166_RS27865	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW166_RS27870	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW166_RS27880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW166_RS27885	COG1301	dicarboxylic acid transport
AW166_RS27895	COG0346	lactoylglutathione lyase activity
AW166_RS27900	COG1511	domain protein
AW166_RS27905	COG0583	DNA-binding transcription factor activity
AW166_RS27910	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW166_RS27930	COG1271	oxidase subunit
AW166_RS27935	COG1294	oxidase, subunit
AW166_RS27940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW166_RS27950	COG1620	l-lactate permease
AW166_RS27960	COG2389	metal-binding protein
AW166_RS27970	COG1368	sulfuric ester hydrolase activity
AW166_RS27985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW166_RS28005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW166_RS28010	COG3584	3D domain protein
AW166_RS28010	COG1388	LysM domain
AW166_RS28035	COG4715	Zinc finger, swim domain protein
AW166_RS28040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW166_RS28080	COG0577	efflux transmembrane transporter activity
AW166_RS28085	COG1136	(ABC) transporter
AW166_RS28120	COG5002	protein histidine kinase activity
AW166_RS28125	COG0745	RESPONSE REGULATOR receiver
AW166_RS28130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW166_RS28145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW166_RS28150	COG1134	teichoic acid transport
AW166_RS28155	COG1682	transport, permease protein
AW166_RS28160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW166_RS28205	COG1609	Transcriptional regulator
AW166_RS28220	COG0739	heme binding
AW166_RS28235	COG3279	Response regulator of the LytR AlgR family
AW166_RS28240	COG4555	ABC transporter
AW166_RS28245	COG2385	sporulation resulting in formation of a cellular spore
AW166_RS28260	COG4836	Membrane
AW166_RS28265	COG1007	ATP synthesis coupled electron transport
AW166_RS28270	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW166_RS28275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW166_RS28285	COG0839	Belongs to the complex I subunit 6 family
AW166_RS28300	COG0649	NAD binding
AW166_RS28305	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW166_RS28320	COG5001	Diguanylate cyclase
AW166_RS28320	COG3300	MHYT domain
AW166_RS28370	COG0356	it plays a direct role in the translocation of protons across the membrane
AW166_RS28405	COG0698	ribose 5-phosphate isomerase
AW166_RS28415	COG2190	(PTS) system
AW166_RS28420	COG2259	Doxx family
AW166_RS28425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW166_RS28440	COG0009	L-threonylcarbamoyladenylate synthase
AW166_RS28455	COG2890	protein-(glutamine-N5) methyltransferase activity
AW166_RS28475	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW166_RS28480	COG1494	fructose-1,6-bisphosphatase
AW166_RS28500	COG4821	SIS domain
AW166_RS28510	COG3343	RNA polymerase activity
AW166_RS28520	COG1960	acyl-CoA dehydrogenase activity
AW166_RS28525	COG1960	acyl-CoA dehydrogenase activity
AW166_RS28530	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW166_RS28535	COG0183	Belongs to the thiolase family
AW166_RS28540	COG0247	lactate metabolic process
AW166_RS28540	COG2181	nitrate reductase activity
AW166_RS28545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW166_RS28555	COG3300	MHYT domain
AW166_RS28555	COG5001	Diguanylate cyclase
AW166_RS28570	COG2197	response regulator
AW166_RS28575	COG4585	Histidine kinase
AW166_RS28580	COG0842	Transport permease protein
AW166_RS28585	COG1131	(ABC) transporter
AW166_RS28590	COG0024	Methionine aminopeptidase
AW166_RS28610	COG2234	aminopeptidase activity
AW166_RS28630	COG1595	DNA-templated transcription, initiation
AW166_RS28635	COG0018	arginyl-trna synthetase
AW166_RS28640	COG4506	Protein conserved in bacteria
AW166_RS28645	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW166_RS28660	COG0010	Belongs to the arginase family
AW166_RS28670	COG2814	Major facilitator Superfamily
AW166_RS28675	COG0789	Transcriptional regulator
AW166_RS28680	COG0584	glycerophosphoryl diester phosphodiesterase
AW166_RS28685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW166_RS28695	COG1994	Peptidase M50
AW166_RS28705	COG1078	dGTPase activity
AW166_RS28710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW166_RS28715	COG1120	ATPase activity
AW166_RS28720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS28725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS28730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW166_RS28750	COG0095	Lipoate-protein ligase
AW166_RS28755	COG0280	phosphate acetyltransferase
AW166_RS28770	COG3773	Cell wall hydrolase
AW166_RS28780	COG2363	Small membrane protein
AW166_RS28795	COG2233	PERMEase
AW166_RS28800	COG0561	phosphatase activity
AW166_RS28805	COG2814	Major facilitator Superfamily
AW166_RS28815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW166_RS28820	COG1131	(ABC) transporter
AW166_RS28825	COG2755	lipolytic protein G-D-S-L family
AW166_RS28830	COG1609	Transcriptional regulator
AW166_RS28840	COG0460	homoserine dehydrogenase
AW166_RS28850	COG2873	o-acetylhomoserine
AW166_RS28860	COG1011	Hydrolase
AW166_RS28865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW166_RS28875	COG2197	response regulator
AW166_RS28885	COG0351	phosphomethylpyrimidine kinase
AW166_RS28890	COG3706	GGDEF domain
AW166_RS28895	COG2879	small protein
AW166_RS28900	COG1966	Carbon starvation protein
AW166_RS28905	COG3279	Response regulator of the LytR AlgR family
AW166_RS28910	COG0477	Major facilitator Superfamily
AW166_RS28935	COG0840	transmembrane signaling receptor activity
AW166_RS28945	COG1607	acyl-coa hydrolase
AW166_RS28960	COG0488	(ABC) transporter
AW166_RS28985	COG0463	Glycosyl transferase, family 2
AW166_RS28990	COG1309	transcriptional regulator
AW166_RS28995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW166_RS29000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW166_RS29000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW166_RS29005	COG0628	permease
AW166_RS29020	COG3279	Response regulator of the LytR AlgR family
AW166_RS29025	COG3275	phosphorelay sensor kinase activity
AW166_RS29030	COG2814	Major facilitator Superfamily
AW166_RS29035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW166_RS29040	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW166_RS29050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW166_RS29070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW166_RS29075	COG1272	protein, Hemolysin III
AW166_RS29095	COG0516	GMP reductase activity
AW166_RS29100	COG1164	Oligoendopeptidase f
AW166_RS29120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW166_RS29125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW166_RS29130	COG4853	Protein conserved in bacteria
AW166_RS29135	COG4863	YycH protein
AW166_RS29140	COG5002	protein histidine kinase activity
AW166_RS29145	COG0745	RESPONSE REGULATOR receiver
AW166_RS29175	COG0305	Participates in initiation and elongation during chromosome replication
AW166_RS29185	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW166_RS29190	COG4241	membrane
AW166_RS29200	COG0629	single-stranded DNA binding
AW166_RS29210	COG0012	GTP binding
AW166_RS29215	COG4481	Protein conserved in bacteria
AW166_RS29220	COG0668	transmembrane transport
AW166_RS29230	COG1475	DNA binding
AW166_RS29235	COG1192	Involved in chromosome partitioning
AW166_RS29260	COG1847	R3H domain protein
AW166_RS29265	COG0706	membrane insertase activity
AW166_RS29275	COG0230	Belongs to the bacterial ribosomal protein bL34 family