locus-tag	class	description
KM391_RS00010	COG0592	DNA-directed DNA polymerase activity
KM391_RS00015	COG2501	S4 domain
KM391_RS00025	COG0187	DNA topoisomerase II activity
KM391_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM391_RS00065	COG0516	GMP reductase activity
KM391_RS00065	COG0517	IMP dehydrogenase activity
KM391_RS00070	COG1686	Belongs to the peptidase S11 family
KM391_RS00100	COG1428	Deoxynucleoside kinase
KM391_RS00105	COG1428	Deoxynucleoside kinase
KM391_RS00110	COG1335	isochorismatase
KM391_RS00115	COG0590	tRNA wobble adenosine to inosine editing
KM391_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM391_RS00180	COG1982	Orn Lys Arg decarboxylase major
KM391_RS00190	COG0470	DNA polymerase III
KM391_RS00195	COG1774	PSP1 C-terminal conserved region
KM391_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM391_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM391_RS00220	COG2002	toxin-antitoxin pair type II binding
KM391_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_RS00230	COG0084	hydrolase, TatD family'
KM391_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM391_RS00250	COG4466	Protein conserved in bacteria
KM391_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM391_RS00270	COG0251	oxidation-reduction process
KM391_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM391_RS00305	COG2002	toxin-antitoxin pair type II binding
KM391_RS00310	COG2244	polysaccharide biosynthetic process
KM391_RS00315	COG3956	TIGRFAM MazG family protein
KM391_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM391_RS00340	COG1098	S1 RNA binding domain
KM391_RS00355	COG2208	phosphoserine phosphatase activity
KM391_RS00360	COG0037	tRNA processing
KM391_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM391_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM391_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM391_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM391_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
KM391_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM391_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM391_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM391_RS00420	COG1396	sequence-specific DNA binding
KM391_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM391_RS00455	COG3880	PFAM UvrB UvrC protein
KM391_RS00465	COG0542	response to heat
KM391_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM391_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
KM391_RS00500	COG1045	serine acetyltransferase
KM391_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM391_RS00520	COG3688	RNA-binding protein containing a PIN domain
KM391_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM391_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
KM391_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KM391_RS00565	COG2813	Specifically methylates the guanine in position
KM391_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KM391_RS00580	COG1358	cellular component organization or biogenesis
KM391_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
KM391_RS00710	COG0201	protein transport
KM391_RS00720	COG0024	Methionine aminopeptidase
KM391_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM391_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM391_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_RS00795	COG0489	protein tyrosine kinase activity
KM391_RS00805	COG2194	sulfuric ester hydrolase activity
KM391_RS00810	COG0726	polysaccharide deacetylase
KM391_RS00890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM391_RS00895	COG4856	YbbR-like protein
KM391_RS00910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KM391_RS00915	COG0596	Alpha beta hydrolase
KM391_RS00935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM391_RS00940	COG4946	Tricorn protease homolog
KM391_RS00940	COG0823	Involved in the tonB-independent uptake of proteins
KM391_RS00940	COG1506	peptidase
KM391_RS00975	COG2011	ABC-type metal ion transport system permease component
KM391_RS00980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM391_RS00985	COG1464	Belongs to the NlpA lipoprotein family
KM391_RS00990	COG0604	alcohol dehydrogenase
KM391_RS01000	COG0277	FAD linked oxidase domain protein
KM391_RS01005	COG2271	Major facilitator Superfamily
KM391_RS01015	COG2814	Major facilitator Superfamily
KM391_RS01030	COG0601	transmembrane transport
KM391_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_RS01040	COG0444	Belongs to the ABC transporter superfamily
KM391_RS01045	COG4608	Belongs to the ABC transporter superfamily
KM391_RS01050	COG4166	transmembrane transport
KM391_RS01060	COG2207	Transcriptional regulator
KM391_RS01075	COG4166	transmembrane transport
KM391_RS01080	COG4166	transmembrane transport
KM391_RS01085	COG0656	L-ascorbic acid biosynthetic process
KM391_RS01105	COG4149	molybdate abc transporter
KM391_RS01115	COG1910	domain protein
KM391_RS01125	COG0583	DNA-binding transcription factor activity
KM391_RS01130	COG0697	spore germination
KM391_RS01145	COG0204	Acyl-transferase
KM391_RS01155	COG1609	Transcriptional regulator
KM391_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS01175	COG0084	hydrolase, TatD family'
KM391_RS01180	COG5298	Protein conserved in bacteria
KM391_RS01205	COG0488	(ABC) transporter
KM391_RS01220	COG0747	negative chemotaxis
KM391_RS01225	COG0601	transmembrane transport
KM391_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_RS01235	COG0444	Belongs to the ABC transporter superfamily
KM391_RS01260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KM391_RS01265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM391_RS01275	COG2814	Major facilitator Superfamily
KM391_RS01285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM391_RS01295	COG4294	response to UV
KM391_RS01300	COG0457	Tetratricopeptide repeat
KM391_RS01300	COG0705	Rhomboid family
KM391_RS01310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM391_RS01315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM391_RS01320	COG0864	Transcriptional regulator
KM391_RS01325	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM391_RS01330	COG2183	response to ionizing radiation
KM391_RS01425	COG0802	atpase or kinase
KM391_RS01430	COG1214	PFAM Peptidase M22, glycoprotease
KM391_RS01435	COG0456	acetyltransferase
KM391_RS01445	COG0488	(ABC) transporter
KM391_RS01460	COG1266	CAAX protease self-immunity
KM391_RS01480	COG2252	PERMEase
KM391_RS01490	COG5002	protein histidine kinase activity
KM391_RS01520	COG2226	methyltransferase
KM391_RS01565	COG1968	undecaprenyl-diphosphatase activity
KM391_RS01580	COG2205	protein histidine kinase activity
KM391_RS01585	COG0745	RESPONSE REGULATOR receiver
KM391_RS01610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM391_RS01615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM391_RS01620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM391_RS01630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM391_RS01645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM391_RS01655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM391_RS01665	COG0151	Belongs to the GarS family
KM391_RS01690	COG0210	DNA helicase
KM391_RS01700	COG4851	CamS sex pheromone cAM373 precursor
KM391_RS01720	COG1335	isochorismatase
KM391_RS01725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM391_RS01730	COG2011	ABC-type metal ion transport system permease component
KM391_RS01735	COG1464	Belongs to the NlpA lipoprotein family
KM391_RS01760	COG1846	Transcriptional regulator
KM391_RS01785	COG1597	lipid kinase activity
KM391_RS01790	COG0546	phosphoglycolate phosphatase activity
KM391_RS01795	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM391_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS01810	COG2076	Multidrug Resistance protein
KM391_RS01815	COG2309	aminopeptidase activity
KM391_RS01830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS01835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM391_RS01840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM391_RS01850	COG4807	Protein conserved in bacteria
KM391_RS01875	COG1757	Na H antiporter
KM391_RS01880	COG1473	amidohydrolase
KM391_RS01895	COG0450	alkyl hydroperoxide reductase
KM391_RS01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS01925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_RS01940	COG0166	Belongs to the GPI family
KM391_RS01975	COG5002	protein histidine kinase activity
KM391_RS01995	COG3541	Predicted nucleotidyltransferase
KM391_RS02000	COG2814	Major facilitator Superfamily
KM391_RS02005	COG0723	plastoquinol--plastocyanin reductase activity
KM391_RS02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_RS02015	COG0765	amino acid transport
KM391_RS02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_RS02030	COG0840	transmembrane signaling receptor activity
KM391_RS02035	COG0840	transmembrane signaling receptor activity
KM391_RS02040	COG0366	Alpha amylase catalytic
KM391_RS02045	COG1263	PTS System
KM391_RS02045	COG2190	(PTS) system
KM391_RS02045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_RS02075	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KM391_RS02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_RS02100	COG1116	anion transmembrane transporter activity
KM391_RS02105	COG0488	(ABC) transporter
KM391_RS02155	COG2270	Major facilitator Superfamily
KM391_RS02170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM391_RS02185	COG2310	stress, protein
KM391_RS02190	COG2310	stress, protein
KM391_RS02195	COG2310	stress, protein
KM391_RS02200	COG0861	Integral membrane protein TerC family
KM391_RS02210	COG3853	Toxic anion resistance protein (TelA)
KM391_RS02225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM391_RS02235	COG1295	ribonuclease BN
KM391_RS02240	COG2217	Heavy metal translocating P-type atpase
KM391_RS02245	COG0697	spore germination
KM391_RS02265	COG0586	Pfam SNARE associated Golgi protein
KM391_RS02280	COG3871	stress protein (general stress protein 26)
KM391_RS02285	COG0387	Pfam Sodium calcium exchanger
KM391_RS02295	COG0535	radical SAM domain protein
KM391_RS02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM391_RS02325	COG0582	viral genome integration into host DNA
KM391_RS02335	COG1396	sequence-specific DNA binding
KM391_RS02350	COG1396	sequence-specific DNA binding
KM391_RS02385	COG1484	DNA-dependent DNA replication
KM391_RS02615	COG0101	tRNA pseudouridine synthase activity
KM391_RS02625	COG3829	transcription factor binding
KM391_RS02635	COG0833	amino acid
KM391_RS02640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM391_RS02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_RS02670	COG1263	PTS System
KM391_RS02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_RS02690	COG0463	Glycosyl transferase, family 2
KM391_RS02700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KM391_RS02700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM391_RS02715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KM391_RS02735	COG1228	amidohydrolase
KM391_RS02740	COG1090	epimerase
KM391_RS02770	COG1988	membrane-bound metal-dependent
KM391_RS02775	COG1194	a g-specific adenine glycosylase
KM391_RS02800	COG1132	(ABC) transporter
KM391_RS02805	COG4129	membrane
KM391_RS02810	COG0070	glutamate synthase
KM391_RS02810	COG0067	glutamate synthase
KM391_RS02810	COG0069	glutamate synthase activity
KM391_RS02820	COG4555	ABC transporter
KM391_RS02840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM391_RS02845	COG0735	belongs to the Fur family
KM391_RS02960	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KM391_RS02965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM391_RS02975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM391_RS02985	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM391_RS02995	COG2766	serine protein kinase
KM391_RS03015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM391_RS03025	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM391_RS03030	COG2268	Band 7 protein
KM391_RS03040	COG3290	protein histidine kinase activity
KM391_RS03050	COG2851	Citrate transporter
KM391_RS03070	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM391_RS03075	COG3842	ATPase activity
KM391_RS03080	COG1175	transmembrane transport
KM391_RS03085	COG0395	ABC-type sugar transport system, permease component
KM391_RS03095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KM391_RS03100	COG0745	RESPONSE REGULATOR receiver
KM391_RS03105	COG5002	protein histidine kinase activity
KM391_RS03115	COG4990	cell redox homeostasis
KM391_RS03125	COG3290	protein histidine kinase activity
KM391_RS03130	COG4565	transcriptional regulatory protein
KM391_RS03135	COG3493	citrate carrier protein
KM391_RS03140	COG0281	malic enzyme
KM391_RS03155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS03165	COG5002	protein histidine kinase activity
KM391_RS03170	COG0745	RESPONSE REGULATOR receiver
KM391_RS03175	COG0454	-acetyltransferase
KM391_RS03175	COG0456	acetyltransferase
KM391_RS03180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM391_RS03185	COG3383	formate dehydrogenase (NAD+) activity
KM391_RS03205	COG0531	amino acid
KM391_RS03210	COG0640	Transcriptional regulator
KM391_RS03215	COG2217	Heavy metal translocating P-type atpase
KM391_RS03220	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM391_RS03235	COG3227	Zinc metalloprotease (Elastase)
KM391_RS03255	COG2720	vancomycin resistance protein
KM391_RS03260	COG1316	TRANSCRIPTIONal
KM391_RS03265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS03270	COG0346	lactoylglutathione lyase activity
KM391_RS03280	COG1027	Aspartate ammonia-lyase
KM391_RS03285	COG1620	l-lactate permease
KM391_RS03300	COG3104	oligopeptide transport
KM391_RS03305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_RS03310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS03315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS03325	COG2226	methyltransferase
KM391_RS03330	COG0156	8-amino-7-oxononanoate synthase activity
KM391_RS03345	COG4548	von Willebrand factor, type A
KM391_RS03350	COG0714	Associated with various cellular activities
KM391_RS03355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_RS03375	COG0531	amino acid
KM391_RS03380	COG2188	Transcriptional regulator
KM391_RS03385	COG1263	PTS System
KM391_RS03385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_RS03390	COG0366	Alpha amylase catalytic
KM391_RS03405	COG0697	spore germination
KM391_RS03415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM391_RS03420	COG1115	amino acid carrier protein
KM391_RS03425	COG1126	abc transporter atp-binding protein
KM391_RS03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_RS03435	COG0765	amino acid transport
KM391_RS03440	COG0765	amino acid transport
KM391_RS03445	COG0833	amino acid
KM391_RS03470	COG2378	regulation of single-species biofilm formation
KM391_RS03475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM391_RS03480	COG5002	protein histidine kinase activity
KM391_RS03495	COG0659	secondary active sulfate transmembrane transporter activity
KM391_RS03510	COG0747	negative chemotaxis
KM391_RS03520	COG0601	transmembrane transport
KM391_RS03525	COG4608	Belongs to the ABC transporter superfamily
KM391_RS03535	COG2271	Major facilitator Superfamily
KM391_RS03540	COG1846	Transcriptional regulator
KM391_RS03550	COG1609	Transcriptional regulator
KM391_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM391_RS03570	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM391_RS03575	COG1879	ABC-type sugar transport system periplasmic component
KM391_RS03600	COG1063	alcohol dehydrogenase
KM391_RS03615	COG3568	Endonuclease Exonuclease Phosphatase
KM391_RS03640	COG1968	undecaprenyl-diphosphatase activity
KM391_RS03645	COG0840	transmembrane signaling receptor activity
KM391_RS03650	COG3584	3D domain protein
KM391_RS03650	COG1388	LysM domain
KM391_RS03655	COG1476	TRANSCRIPTIONal
KM391_RS03670	COG3104	oligopeptide transport
KM391_RS03675	COG1114	Component of the transport system for branched-chain amino acids
KM391_RS03690	COG1113	amino acid transport
KM391_RS03695	COG2252	PERMEase
KM391_RS03720	COG0475	glutathione-regulated potassium exporter activity
KM391_RS03720	COG0569	domain protein
KM391_RS03735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM391_RS03740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM391_RS03745	COG4990	cell redox homeostasis
KM391_RS03760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_RS03765	COG0697	spore germination
KM391_RS03770	COG0531	amino acid
KM391_RS03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM391_RS03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM391_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KM391_RS03790	COG1918	ferrous iron import across plasma membrane
KM391_RS03795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM391_RS03800	COG0573	inorganic phosphate transmembrane transporter activity
KM391_RS03805	COG0581	inorganic phosphate transmembrane transporter activity
KM391_RS03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM391_RS03930	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM391_RS03950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM391_RS03955	COG1116	anion transmembrane transporter activity
KM391_RS03960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_RS03965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM391_RS03970	COG0352	thiamine-phosphate diphosphorylase activity
KM391_RS03975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_RS03980	COG2104	thiamine diphosphate biosynthetic process
KM391_RS03990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_RS03995	COG0351	phosphomethylpyrimidine kinase
KM391_RS04035	COG2205	protein histidine kinase activity
KM391_RS04040	COG2814	Major facilitator Superfamily
KM391_RS04045	COG1846	Transcriptional regulator
KM391_RS04060	COG2252	PERMEase
KM391_RS04065	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS04080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM391_RS04085	COG1621	beta-fructofuranosidase activity
KM391_RS04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_RS04090	COG1263	PTS System
KM391_RS04095	COG1609	Transcriptional regulator
KM391_RS04105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_RS04110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM391_RS04145	COG0778	Nitroreductase
KM391_RS04150	COG2719	SpoVR family
KM391_RS04175	COG0446	pyridine nucleotide-disulphide oxidoreductase
KM391_RS04180	COG1937	Protein conserved in bacteria
KM391_RS04185	COG0425	Belongs to the sulfur carrier protein TusA family
KM391_RS04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_RS04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_RS04195	COG0425	Belongs to the sulfur carrier protein TusA family
KM391_RS04210	COG2210	Belongs to the sulfur carrier protein TusA family
KM391_RS04215	COG0730	response to heat
KM391_RS04225	COG1316	TRANSCRIPTIONal
KM391_RS04230	COG0604	alcohol dehydrogenase
KM391_RS04235	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM391_RS04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM391_RS04250	COG3711	transcriptional antiterminator
KM391_RS04255	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM391_RS04260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM391_RS04280	COG1388	LysM domain
KM391_RS04280	COG3584	3D domain protein
KM391_RS04285	COG0577	efflux transmembrane transporter activity
KM391_RS04290	COG1136	(ABC) transporter
KM391_RS04300	COG5522	Integral membrane protein (intg_mem_TP0381)
KM391_RS04315	COG1114	Component of the transport system for branched-chain amino acids
KM391_RS04320	COG3546	catalase activity
KM391_RS04355	COG0586	Pfam SNARE associated Golgi protein
KM391_RS04390	COG0531	amino acid
KM391_RS04395	COG0475	glutathione-regulated potassium exporter activity
KM391_RS04405	COG1737	Transcriptional regulator
KM391_RS04415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_RS04415	COG1263	PTS System
KM391_RS04425	COG2259	Doxx family
KM391_RS04440	COG0697	spore germination
KM391_RS04445	COG1522	sequence-specific DNA binding
KM391_RS04460	COG2076	Multidrug Resistance protein
KM391_RS04465	COG1309	transcriptional regulator
KM391_RS04470	COG2814	Major facilitator Superfamily
KM391_RS04475	COG1733	regulation of RNA biosynthetic process
KM391_RS04485	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM391_RS04490	COG4533	DNA binding
KM391_RS04495	COG2211	Major facilitator Superfamily
KM391_RS04505	COG0693	protein deglycase activity
KM391_RS04510	COG0753	catalase activity
KM391_RS04520	COG0531	amino acid
KM391_RS04525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KM391_RS04535	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS04540	COG1132	(ABC) transporter
KM391_RS04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_RS04555	COG0765	amino acid transport
KM391_RS04560	COG1126	abc transporter atp-binding protein
KM391_RS04575	COG0189	ligase activity
KM391_RS04605	COG0028	Belongs to the TPP enzyme family
KM391_RS04610	COG3527	Alpha-acetolactate decarboxylase
KM391_RS04625	COG0561	phosphatase activity
KM391_RS04640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM391_RS04655	COG0659	secondary active sulfate transmembrane transporter activity
KM391_RS04675	COG0653	protein targeting
KM391_RS04680	COG2244	polysaccharide biosynthetic process
KM391_RS04690	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_RS04695	COG4196	transglutaminase domain protein
KM391_RS04710	COG1696	Membrane protein involved in D-alanine export
KM391_RS04725	COG1024	Enoyl-CoA hydratase
KM391_RS04745	COG1363	Peptidase, m42
KM391_RS04765	COG3938	Belongs to the proline racemase family
KM391_RS04805	COG0601	transmembrane transport
KM391_RS04810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_RS04820	COG4608	Belongs to the ABC transporter superfamily
KM391_RS04855	COG0477	Major facilitator Superfamily
KM391_RS04860	COG3290	protein histidine kinase activity
KM391_RS04865	COG4565	transcriptional regulatory protein
KM391_RS04870	COG3181	Tripartite tricarboxylate transporter family receptor
KM391_RS04900	COG0789	Transcriptional regulator
KM391_RS04900	COG4978	Transcriptional regulator
KM391_RS04915	COG0305	Participates in initiation and elongation during chromosome replication
KM391_RS04955	COG0477	Major facilitator Superfamily
KM391_RS05000	COG3320	Male sterility
KM391_RS05000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM391_RS05005	COG1309	transcriptional regulator
KM391_RS05025	COG1183	phosphatidylcholine synthase activity
KM391_RS05045	COG2376	Dihydroxyacetone kinase
KM391_RS05055	COG2376	Dihydroxyacetone kinase
KM391_RS05060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM391_RS05065	COG1959	2 iron, 2 sulfur cluster binding
KM391_RS05095	COG3437	response regulator, receiver
KM391_RS05095	COG2770	Histidine kinase
KM391_RS05145	COG3237	CsbD-like
KM391_RS05170	COG1191	sigma factor activity
KM391_RS05180	COG2208	phosphoserine phosphatase activity
KM391_RS05185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM391_RS05190	COG0784	Response regulator, receiver
KM391_RS05190	COG2198	Histidine kinase
KM391_RS05190	COG2205	protein histidine kinase activity
KM391_RS05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_RS05245	COG0420	3'-5' exonuclease activity
KM391_RS05270	COG1309	transcriptional regulator
KM391_RS05275	COG2814	Major facilitator Superfamily
KM391_RS05280	COG0346	lactoylglutathione lyase activity
KM391_RS05285	COG0346	lactoylglutathione lyase activity
KM391_RS05290	COG0457	Tetratricopeptide repeat
KM391_RS05295	COG2267	carboxylic ester hydrolase activity
KM391_RS05315	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM391_RS05320	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM391_RS05330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM391_RS05370	COG0477	Major facilitator Superfamily
KM391_RS05375	COG0477	Major facilitator Superfamily
KM391_RS05385	COG3973	AAA domain
KM391_RS05390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM391_RS05410	COG4980	gas vesicle protein
KM391_RS05415	COG0537	adenosine 5'-monophosphoramidase activity
KM391_RS05420	COG1131	(ABC) transporter
KM391_RS05425	COG4473	ABC transporter
KM391_RS05440	COG1309	transcriptional regulator
KM391_RS05450	COG3402	PFAM membrane-flanked domain
KM391_RS05495	COG3402	PFAM membrane-flanked domain
KM391_RS05500	COG3428	Bacterial PH domain
KM391_RS05505	COG2329	Antibiotic biosynthesis monooxygenase
KM391_RS05510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_RS05515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KM391_RS05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM391_RS05525	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM391_RS05560	COG1309	transcriptional regulator
KM391_RS05565	COG1511	domain protein
KM391_RS05600	COG1234	tRNA 3'-trailer cleavage
KM391_RS05605	COG0095	Lipoate-protein ligase
KM391_RS05615	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_RS05645	COG3209	COG3209 Rhs family protein
KM391_RS05685	COG1078	dGTPase activity
KM391_RS05695	COG1595	DNA-templated transcription, initiation
KM391_RS05700	COG3708	Transcriptional regulator
KM391_RS05700	COG2207	Transcriptional regulator
KM391_RS05715	COG2205	protein histidine kinase activity
KM391_RS05720	COG0745	RESPONSE REGULATOR receiver
KM391_RS05745	COG0501	Belongs to the peptidase M48B family
KM391_RS05750	COG0840	transmembrane signaling receptor activity
KM391_RS05755	COG0697	spore germination
KM391_RS05775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KM391_RS05780	COG2224	Isocitrate lyase
KM391_RS05805	COG4903	ComK protein
KM391_RS05810	COG0398	Pfam SNARE associated Golgi protein
KM391_RS05820	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KM391_RS05825	COG1074	ATP-dependent DNA helicase activity
KM391_RS05870	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM391_RS05895	COG0367	asparagine synthase
KM391_RS05900	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM391_RS05905	COG0753	catalase activity
KM391_RS05910	COG0004	ammonium transporteR
KM391_RS05930	COG2996	Protein conserved in bacteria
KM391_RS05940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM391_RS05950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS05965	COG0561	phosphatase activity
KM391_RS05975	COG0542	response to heat
KM391_RS05985	COG2267	carboxylic ester hydrolase activity
KM391_RS06000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_RS06005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM391_RS06010	COG5504	Zn-dependent protease
KM391_RS06020	COG0180	Tryptophanyl-tRNA synthetase
KM391_RS06030	COG4166	transmembrane transport
KM391_RS06035	COG0601	transmembrane transport
KM391_RS06040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_RS06045	COG0444	Belongs to the ABC transporter superfamily
KM391_RS06050	COG4608	Belongs to the ABC transporter superfamily
KM391_RS06055	COG0534	Mate efflux family protein
KM391_RS06060	COG4166	transmembrane transport
KM391_RS06075	COG0861	Integral membrane protein TerC family
KM391_RS06080	COG4862	establishment of competence for transformation
KM391_RS06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_RS06095	COG1164	Oligoendopeptidase f
KM391_RS06105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM391_RS06110	COG2346	COG2346, Truncated hemoglobins
KM391_RS06115	COG4116	CYTH
KM391_RS06125	COG2357	RelA SpoT domain protein
KM391_RS06135	COG0564	pseudouridine synthase activity
KM391_RS06155	COG0463	Glycosyl transferase, family 2
KM391_RS06155	COG1216	Glycosyl transferase, family 2
KM391_RS06175	COG0457	Tetratricopeptide repeat
KM391_RS06175	COG0463	Glycosyl transferase, family 2
KM391_RS06195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM391_RS06210	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM391_RS06255	COG2153	protein acetylation
KM391_RS06265	COG2382	esterase
KM391_RS06280	COG5492	domain, Protein
KM391_RS06285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_RS06295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KM391_RS06295	COG0512	Glutamine amidotransferase of anthranilate synthase
KM391_RS06330	COG1620	l-lactate permease
KM391_RS06335	COG5634	Uncharacterized conserved protein (DUF2278)
KM391_RS06390	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_RS06400	COG1476	TRANSCRIPTIONal
KM391_RS06460	COG2226	methyltransferase
KM391_RS06470	COG1686	Belongs to the peptidase S11 family
KM391_RS06475	COG0681	Belongs to the peptidase S26 family
KM391_RS06510	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS06515	COG3842	ATPase activity
KM391_RS06520	COG1176	ABC-type spermidine putrescine transport system, permease component I
KM391_RS06525	COG1177	transmembrane transport
KM391_RS06530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KM391_RS06540	COG2409	Drug exporters of the RND superfamily
KM391_RS06550	COG0564	pseudouridine synthase activity
KM391_RS06560	COG2340	Cysteine-rich secretory protein family
KM391_RS06565	COG0247	lactate metabolic process
KM391_RS06570	COG0277	FAD linked oxidase domain protein
KM391_RS06575	COG3835	regulator
KM391_RS06585	COG0745	RESPONSE REGULATOR receiver
KM391_RS06590	COG5002	protein histidine kinase activity
KM391_RS06595	COG2186	Transcriptional regulator
KM391_RS06615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM391_RS06625	COG2116	formate transmembrane transporter activity
KM391_RS06630	COG0861	Integral membrane protein TerC family
KM391_RS06635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM391_RS06645	COG2030	dehydratase
KM391_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS06670	COG3243	poly(R)-hydroxyalkanoic acid synthase
KM391_RS06675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_RS06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM391_RS06695	COG1840	ABC-type Fe3 transport system, periplasmic component
KM391_RS06725	COG1349	DNA-binding transcription factor activity
KM391_RS06745	COG2861	carbohydrate metabolic process
KM391_RS06755	COG3852	Histidine kinase
KM391_RS06760	COG1846	Transcriptional regulator
KM391_RS06770	COG2318	DinB family
KM391_RS06780	COG5002	protein histidine kinase activity
KM391_RS06790	COG0720	synthase
KM391_RS06805	COG4873	Protein conserved in bacteria
KM391_RS06835	COG1780	Probably involved in ribonucleotide reductase function
KM391_RS06855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM391_RS06860	COG1725	Transcriptional regulator
KM391_RS06865	COG1131	(ABC) transporter
KM391_RS06875	COG1131	(ABC) transporter
KM391_RS06880	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM391_RS06895	COG1522	sequence-specific DNA binding
KM391_RS06905	COG1335	isochorismatase
KM391_RS06915	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM391_RS06920	COG2070	2-Nitropropane dioxygenase
KM391_RS06925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM391_RS06935	COG1696	Membrane protein involved in D-alanine export
KM391_RS06960	COG0716	FMN binding
KM391_RS06975	COG3173	Aminoglycoside phosphotransferase
KM391_RS06995	COG0534	Mate efflux family protein
KM391_RS07000	COG1968	undecaprenyl-diphosphatase activity
KM391_RS07015	COG1846	Transcriptional regulator
KM391_RS07025	COG1301	dicarboxylic acid transport
KM391_RS07030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM391_RS07035	COG4709	membrane
KM391_RS07040	COG3874	Sporulation protein YtfJ
KM391_RS07065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_RS07070	COG0028	Belongs to the TPP enzyme family
KM391_RS07075	COG0440	acetolactate synthase activity
KM391_RS07080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM391_RS07090	COG0473	3-isopropylmalate dehydrogenase activity
KM391_RS07115	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM391_RS07150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM391_RS07165	COG1183	phosphatidylcholine synthase activity
KM391_RS07170	COG1368	sulfuric ester hydrolase activity
KM391_RS07180	COG0019	diaminopimelate decarboxylase activity
KM391_RS07200	COG0529	Catalyzes the synthesis of activated sulfate
KM391_RS07205	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM391_RS07225	COG1648	precorrin-2 dehydrogenase activity
KM391_RS07230	COG0733	neurotransmitter:sodium symporter activity
KM391_RS07250	COG1757	Na H antiporter
KM391_RS07265	COG4758	membrane
KM391_RS07270	COG4585	Histidine kinase
KM391_RS07275	COG2197	response regulator
KM391_RS07285	COG1114	Component of the transport system for branched-chain amino acids
KM391_RS07295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM391_RS07320	COG1017	nitric oxide dioxygenase activity
KM391_RS07320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM391_RS07335	COG0730	response to heat
KM391_RS07340	COG0306	phosphate transporter
KM391_RS07345	COG1392	Phosphate transport regulator
KM391_RS07350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_RS07370	COG1801	Protein of unknown function DUF72
KM391_RS07380	COG0582	viral genome integration into host DNA
KM391_RS07385	COG5002	protein histidine kinase activity
KM391_RS07405	COG0392	lysyltransferase activity
KM391_RS07405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM391_RS07420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM391_RS07425	COG1686	Belongs to the peptidase S11 family
KM391_RS07430	COG2715	membrane protein required for spore maturation
KM391_RS07435	COG0700	Nucleoside recognition
KM391_RS07440	COG1187	pseudouridine synthase activity
KM391_RS07450	COG1333	cytochrome c biogenesis protein
KM391_RS07455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM391_RS07460	COG0745	RESPONSE REGULATOR receiver
KM391_RS07465	COG5002	protein histidine kinase activity
KM391_RS07470	COG2096	Adenosyltransferase
KM391_RS07485	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM391_RS07490	COG1141	Ferredoxin
KM391_RS07495	COG4955	Helix-turn-helix domain
KM391_RS07500	COG0514	ATP-dependent DNA helicase (RecQ)
KM391_RS07505	COG1266	CAAX protease self-immunity
KM391_RS07525	COG4862	establishment of competence for transformation
KM391_RS07530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM391_RS07550	COG0492	ferredoxin-NADP+ reductase activity
KM391_RS07555	COG0252	asparaginase activity
KM391_RS07625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM391_RS07640	COG0142	geranyltranstransferase activity
KM391_RS07650	COG0142	geranyltranstransferase activity
KM391_RS07670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM391_RS07675	COG0457	Tetratricopeptide repeat
KM391_RS07695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM391_RS07705	COG4347	Protein of unknown function (DUF1405)
KM391_RS07720	COG2738	Putative neutral zinc metallopeptidase
KM391_RS07730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS07735	COG1694	Mazg nucleotide pyrophosphohydrolase
KM391_RS07750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM391_RS07755	COG0438	transferase activity, transferring glycosyl groups
KM391_RS07790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM391_RS07790	COG1199	ATP-dependent helicase activity
KM391_RS07810	COG3935	DnaD domain protein
KM391_RS07815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM391_RS07825	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM391_RS07825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_RS07885	COG0116	Belongs to the methyltransferase superfamily
KM391_RS07895	COG1199	ATP-dependent helicase activity
KM391_RS07900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM391_RS07910	COG3173	Aminoglycoside phosphotransferase
KM391_RS07915	COG0024	Methionine aminopeptidase
KM391_RS07925	COG2233	PERMEase
KM391_RS07930	COG2311	Membrane
KM391_RS07935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM391_RS07945	COG0456	acetyltransferase
KM391_RS07995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM391_RS08020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM391_RS08035	COG1215	transferase activity, transferring glycosyl groups
KM391_RS08040	COG0438	transferase activity, transferring glycosyl groups
KM391_RS08055	COG0454	-acetyltransferase
KM391_RS08075	COG0328	RNA-DNA hybrid ribonuclease activity
KM391_RS08115	COG1280	lysine exporter protein (LysE YggA)
KM391_RS08130	COG3162	membrane
KM391_RS08135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_RS08140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM391_RS08150	COG0475	glutathione-regulated potassium exporter activity
KM391_RS08155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM391_RS08160	COG4978	Transcriptional regulator
KM391_RS08160	COG0789	Transcriptional regulator
KM391_RS08170	COG2323	membrane
KM391_RS08175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KM391_RS08230	COG1923	regulation of RNA biosynthetic process
KM391_RS08240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM391_RS08245	COG1360	Flagellar Motor Protein
KM391_RS08250	COG2201	protein-glutamate methylesterase activity
KM391_RS08260	COG1776	CheC inhibitor of MCP methylation
KM391_RS08260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM391_RS08275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM391_RS08295	COG1256	bacterial-type flagellum assembly
KM391_RS08320	COG1815	bacterial-type flagellum-dependent cell motility
KM391_RS08325	COG1558	bacterial-type flagellum-dependent cell motility
KM391_RS08340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM391_RS08350	COG1157	protein secretion by the type III secretion system
KM391_RS08395	COG0463	Glycosyl transferase, family 2
KM391_RS08420	COG0457	Tetratricopeptide repeat
KM391_RS08420	COG0463	Glycosyl transferase, family 2
KM391_RS08435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM391_RS08440	COG0741	lytic transglycosylase activity
KM391_RS08455	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM391_RS08455	COG1776	CheC inhibitor of MCP methylation
KM391_RS08465	COG1338	Plays a role in the flagellum-specific transport system
KM391_RS08470	COG1987	bacterial-type flagellum assembly
KM391_RS08480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM391_RS08485	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM391_RS08495	COG4786	Flagellar basal body rod
KM391_RS08500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM391_RS08525	COG1309	transcriptional regulator
KM391_RS08545	COG2329	Antibiotic biosynthesis monooxygenase
KM391_RS08570	COG0583	DNA-binding transcription factor activity
KM391_RS08580	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM391_RS08590	COG1234	tRNA 3'-trailer cleavage
KM391_RS08615	COG1686	Belongs to the peptidase S11 family
KM391_RS08625	COG0406	alpha-ribazole phosphatase activity
KM391_RS08655	COG0367	asparagine synthase
KM391_RS08685	COG1802	Transcriptional regulator
KM391_RS08690	COG0697	spore germination
KM391_RS08695	COG0523	cobalamin synthesis protein
KM391_RS08700	COG0701	Predicted permease
KM391_RS08710	COG0438	transferase activity, transferring glycosyl groups
KM391_RS08710	COG1216	Glycosyl transferase, family 2
KM391_RS08715	COG1757	Na H antiporter
KM391_RS08720	COG0114	fumarate hydratase activity
KM391_RS08745	COG3340	Belongs to the peptidase S51 family
KM391_RS08765	COG0785	Cytochrome C biogenesis protein
KM391_RS08795	COG2733	membrane
KM391_RS08830	COG1131	(ABC) transporter
KM391_RS08845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_RS08850	COG0528	UMP kinase activity
KM391_RS08860	COG1027	Aspartate ammonia-lyase
KM391_RS08865	COG0281	malic enzyme
KM391_RS08870	COG4191	Histidine kinase
KM391_RS08875	COG0784	Response regulator, receiver
KM391_RS08880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM391_RS08940	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_RS08950	COG2814	Major facilitator Superfamily
KM391_RS08965	COG1966	Carbon starvation protein
KM391_RS08980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_RS08990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM391_RS09000	COG2223	nitrite transmembrane transporter activity
KM391_RS09005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM391_RS09020	COG2244	polysaccharide biosynthetic process
KM391_RS09025	COG0733	neurotransmitter:sodium symporter activity
KM391_RS09035	COG5566	PFAM Mor transcription activator
KM391_RS09040	COG2323	membrane
KM391_RS09060	COG2084	Dehydrogenase
KM391_RS09075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM391_RS09085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_RS09090	COG0028	Belongs to the TPP enzyme family
KM391_RS09095	COG0440	acetolactate synthase activity
KM391_RS09100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KM391_RS09110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM391_RS09135	COG2814	Major facilitator Superfamily
KM391_RS09140	COG3384	dioxygenase
KM391_RS09150	COG3279	Response regulator of the LytR AlgR family
KM391_RS09155	COG0427	acetyl-CoA hydrolase
KM391_RS09175	COG1073	alpha beta
KM391_RS09205	COG0535	radical SAM domain protein
KM391_RS09210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS09230	COG1914	H( )-stimulated, divalent metal cation uptake system
KM391_RS09245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM391_RS09275	COG2390	Transcriptional regulator
KM391_RS09285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS09290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM391_RS09305	COG4224	UPF0291 protein
KM391_RS09325	COG0006	proline dipeptidase activity
KM391_RS09330	COG2132	Multicopper oxidase
KM391_RS09345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM391_RS09360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM391_RS09375	COG2372	response to copper ion
KM391_RS09375	COG1276	copper resistance
KM391_RS09380	COG4549	nuclear export factor GLE1
KM391_RS09390	COG0697	spore germination
KM391_RS09395	COG0583	DNA-binding transcription factor activity
KM391_RS09400	COG1959	2 iron, 2 sulfur cluster binding
KM391_RS09405	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM391_RS09410	COG0778	Nitroreductase
KM391_RS09420	COG0628	permease
KM391_RS09430	COG1231	oxidoreductase activity
KM391_RS09435	COG0523	cobalamin synthesis protein
KM391_RS09450	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_RS09455	COG2030	dehydratase
KM391_RS09460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_RS09470	COG0411	ABC transporter
KM391_RS09490	COG0583	DNA-binding transcription factor activity
KM391_RS09500	COG1942	4-Oxalocrotonate Tautomerase
KM391_RS09510	COG1846	Transcriptional regulator
KM391_RS09520	COG1271	oxidase subunit
KM391_RS09525	COG1294	oxidase, subunit
KM391_RS09530	COG4988	ABC transporter
KM391_RS09535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM391_RS09555	COG1686	Belongs to the peptidase S11 family
KM391_RS09570	COG0791	NLP P60 protein
KM391_RS09570	COG1388	LysM domain
KM391_RS09585	COG0745	RESPONSE REGULATOR receiver
KM391_RS09590	COG5002	protein histidine kinase activity
KM391_RS09600	COG0300	oxidoreductase activity
KM391_RS09635	COG0460	homoserine dehydrogenase
KM391_RS09660	COG1316	TRANSCRIPTIONal
KM391_RS09670	COG0745	RESPONSE REGULATOR receiver
KM391_RS09675	COG5002	protein histidine kinase activity
KM391_RS09690	COG1285	pathogenesis
KM391_RS09695	COG1247	-acetyltransferase
KM391_RS09715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM391_RS09725	COG1082	Xylose isomerase domain protein TIM barrel
KM391_RS09740	COG1279	arginine transmembrane transporter activity
KM391_RS09750	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM391_RS09790	COG2002	toxin-antitoxin pair type II binding
KM391_RS09795	COG1404	Belongs to the peptidase S8 family
KM391_RS09800	COG0640	Transcriptional regulator
KM391_RS09805	COG0667	Aldo Keto reductase
KM391_RS09810	COG2814	Major facilitator Superfamily
KM391_RS09835	COG0840	transmembrane signaling receptor activity
KM391_RS09850	COG3949	Membrane
KM391_RS09855	COG0783	Belongs to the Dps family
KM391_RS09870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM391_RS09880	COG1231	oxidoreductase activity
KM391_RS09890	COG4989	oxidoreductase activity
KM391_RS09895	COG0523	cobalamin synthesis protein
KM391_RS09900	COG0456	acetyltransferase
KM391_RS09960	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM391_RS09960	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM391_RS09970	COG0702	epimerase
KM391_RS09980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM391_RS09990	COG4166	transmembrane transport
KM391_RS10005	COG0406	alpha-ribazole phosphatase activity
KM391_RS10015	COG5337	Spore coat protein CotH
KM391_RS10020	COG1051	belongs to the nudix hydrolase family
KM391_RS10025	COG0586	Pfam SNARE associated Golgi protein
KM391_RS10030	COG2244	polysaccharide biosynthetic process
KM391_RS10040	COG0701	Predicted permease
KM391_RS10045	COG3689	TIGRFAM TIGR03943 family protein
KM391_RS10050	COG1607	acyl-coa hydrolase
KM391_RS10075	COG0702	epimerase
KM391_RS10080	COG2839	Protein conserved in bacteria
KM391_RS10085	COG1253	flavin adenine dinucleotide binding
KM391_RS10100	COG1114	Component of the transport system for branched-chain amino acids
KM391_RS10105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_RS10125	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_RS10135	COG1876	peptidase activity
KM391_RS10145	COG0154	amidase activity
KM391_RS10150	COG2211	Major facilitator Superfamily
KM391_RS10170	COG0561	phosphatase activity
KM391_RS10180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM391_RS10185	COG4106	trans-aconitate 2-methyltransferase activity
KM391_RS10200	COG1819	glycosyl
KM391_RS10205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS10210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS10245	COG0456	acetyltransferase
KM391_RS10300	COG3874	Sporulation protein YtfJ
KM391_RS10325	COG2226	methyltransferase
KM391_RS10350	COG0346	lactoylglutathione lyase activity
KM391_RS10360	COG0604	alcohol dehydrogenase
KM391_RS10365	COG1595	DNA-templated transcription, initiation
KM391_RS10390	COG0386	Belongs to the glutathione peroxidase family
KM391_RS10395	COG1305	Transglutaminase-like
KM391_RS10400	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM391_RS10405	COG0714	Associated with various cellular activities
KM391_RS10420	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM391_RS10425	COG1140	nitrate reductase beta subunit
KM391_RS10430	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM391_RS10435	COG2181	nitrate reductase activity
KM391_RS10455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM391_RS10460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KM391_RS10465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_RS10470	COG0303	'Molybdopterin
KM391_RS10475	COG0314	molybdopterin synthase activity
KM391_RS10485	COG2223	nitrite transmembrane transporter activity
KM391_RS10500	COG1648	precorrin-2 dehydrogenase activity
KM391_RS10510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM391_RS10510	COG1587	Uroporphyrinogen-III synthase
KM391_RS10515	COG2146	nitrite reductase [NAD(P)H] activity
KM391_RS10520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM391_RS10525	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KM391_RS10560	COG2359	stage V sporulation protein S
KM391_RS10585	COG1418	mRNA catabolic process
KM391_RS10590	COG0488	(ABC) transporter
KM391_RS10605	COG0629	single-stranded DNA binding
KM391_RS10620	COG1413	lyase activity
KM391_RS10635	COG2521	methyltransferase
KM391_RS10635	COG2136	Putative SAM-dependent methyltransferase
KM391_RS10640	COG0018	arginyl-trna synthetase
KM391_RS10665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM391_RS10685	COG0017	Asparaginyl-tRNA synthetase
KM391_RS10705	COG1674	ftsk spoiiie
KM391_RS10775	COG1929	Belongs to the glycerate kinase type-1 family
KM391_RS10780	COG0471	metal ion transport
KM391_RS10785	COG0745	RESPONSE REGULATOR receiver
KM391_RS10790	COG5002	protein histidine kinase activity
KM391_RS10790	COG3850	Histidine kinase
KM391_RS10805	COG0733	neurotransmitter:sodium symporter activity
KM391_RS10830	COG2610	gluconate transmembrane transporter activity
KM391_RS10835	COG1454	alcohol dehydrogenase
KM391_RS10840	COG1794	racemase activity, acting on amino acids and derivatives
KM391_RS10850	COG0456	acetyltransferase
KM391_RS10865	COG1131	(ABC) transporter
KM391_RS10880	COG0546	phosphoglycolate phosphatase activity
KM391_RS10900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_RS10915	COG0768	penicillin binding
KM391_RS10920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM391_RS10925	COG0204	Acyl-transferase
KM391_RS10930	COG1272	protein, Hemolysin III
KM391_RS10940	COG0805	protein transport
KM391_RS10950	COG1307	EDD domain protein, DegV family
KM391_RS10955	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM391_RS10960	COG1999	signal sequence binding
KM391_RS10965	COG0071	Belongs to the small heat shock protein (HSP20) family
KM391_RS10970	COG0367	asparagine synthase
KM391_RS10985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_RS10990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM391_RS11025	COG0668	transmembrane transport
KM391_RS11030	COG4585	Histidine kinase
KM391_RS11030	COG2203	Gaf domain
KM391_RS11035	COG2197	response regulator
KM391_RS11045	COG1064	alcohol dehydrogenase
KM391_RS11100	COG1125	glycine betaine transport
KM391_RS11100	COG0517	IMP dehydrogenase activity
KM391_RS11105	COG1174	glycine betaine transport
KM391_RS11140	COG1253	flavin adenine dinucleotide binding
KM391_RS11145	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS11150	COG5506	Protein of unknown function (DUF1694)
KM391_RS11165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM391_RS11170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM391_RS11175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM391_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM391_RS11185	COG0456	acetyltransferase
KM391_RS11190	COG3829	transcription factor binding
KM391_RS11195	COG1509	lysine 2,3-aminomutase activity
KM391_RS11235	COG4326	sporulation control protein
KM391_RS11240	COG0671	phosphoesterase, PA-phosphatase related
KM391_RS11245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM391_RS11250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_RS11280	COG1787	Restriction endonuclease
KM391_RS11280	COG1715	Restriction endonuclease
KM391_RS11370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM391_RS11410	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM391_RS11410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_RS11420	COG2814	Major facilitator Superfamily
KM391_RS11425	COG4841	protein insertion into membrane
KM391_RS11430	COG0372	Belongs to the citrate synthase family
KM391_RS11435	COG2079	MmgE PrpD family protein
KM391_RS11440	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM391_RS11445	COG1960	acyl-CoA dehydrogenase activity
KM391_RS11450	COG2084	Dehydrogenase
KM391_RS11460	COG1280	lysine exporter protein (LysE YggA)
KM391_RS11465	COG1024	Enoyl-CoA hydratase
KM391_RS11480	COG0420	3'-5' exonuclease activity
KM391_RS11485	COG0419	ATPase involved in DNA repair
KM391_RS11505	COG2223	nitrite transmembrane transporter activity
KM391_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS11515	COG1169	isochorismate synthase
KM391_RS11520	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM391_RS11525	COG1535	isochorismatase
KM391_RS11525	COG3433	isochorismatase activity
KM391_RS11530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM391_RS11535	COG3251	PFAM MbtH domain protein
KM391_RS11540	COG2814	Major facilitator Superfamily
KM391_RS11555	COG0776	regulation of translation
KM391_RS11565	COG2318	DinB family
KM391_RS11575	COG1115	amino acid carrier protein
KM391_RS11590	COG2329	Antibiotic biosynthesis monooxygenase
KM391_RS11595	COG1187	pseudouridine synthase activity
KM391_RS11600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM391_RS11615	COG0596	Alpha beta hydrolase
KM391_RS11620	COG2814	Major facilitator Superfamily
KM391_RS11640	COG2226	methyltransferase
KM391_RS11685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS11720	COG1247	-acetyltransferase
KM391_RS11750	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM391_RS11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS11770	COG1278	Cold shock
KM391_RS11785	COG0010	Belongs to the arginase family
KM391_RS11790	COG0561	phosphatase activity
KM391_RS11835	COG0583	DNA-binding transcription factor activity
KM391_RS11840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM391_RS11855	COG0583	DNA-binding transcription factor activity
KM391_RS11860	COG2258	MOSC domain
KM391_RS11875	COG1132	(ABC) transporter
KM391_RS11880	COG1132	(ABC) transporter
KM391_RS11900	COG1396	sequence-specific DNA binding
KM391_RS11925	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KM391_RS11930	COG1595	DNA-templated transcription, initiation
KM391_RS11955	COG1649	PFAM Uncharacterised BCR, COG1649
KM391_RS11980	COG2971	BadF BadG BcrA BcrD
KM391_RS11985	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM391_RS11990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM391_RS12010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS12040	COG1309	transcriptional regulator
KM391_RS12055	COG0577	efflux transmembrane transporter activity
KM391_RS12055	COG1136	(ABC) transporter
KM391_RS12060	COG3615	Tellurite resistance protein tehB
KM391_RS12060	COG0500	methyltransferase
KM391_RS12070	COG2226	methyltransferase
KM391_RS12075	COG3961	Belongs to the TPP enzyme family
KM391_RS12080	COG1846	Transcriptional regulator
KM391_RS12120	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM391_RS12135	COG1595	DNA-templated transcription, initiation
KM391_RS12155	COG2367	Beta-lactamase
KM391_RS12160	COG0671	phosphoesterase, PA-phosphatase related
KM391_RS12165	COG1609	Transcriptional regulator
KM391_RS12170	COG2814	Major facilitator Superfamily
KM391_RS12175	COG0673	inositol 2-dehydrogenase activity
KM391_RS12185	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS12200	COG0191	fructose-bisphosphate aldolase activity
KM391_RS12205	COG3718	enzyme involved in inositol metabolism
KM391_RS12230	COG0457	Tetratricopeptide repeat
KM391_RS12235	COG1476	TRANSCRIPTIONal
KM391_RS12250	COG1876	peptidase activity
KM391_RS12270	COG1309	transcriptional regulator
KM391_RS12275	COG0488	(ABC) transporter
KM391_RS12290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS12305	COG1252	NADH dehydrogenase
KM391_RS12310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_RS12325	COG1131	(ABC) transporter
KM391_RS12335	COG1309	transcriptional regulator
KM391_RS12350	COG1960	acyl-CoA dehydrogenase activity
KM391_RS12355	COG0439	Biotin carboxylase
KM391_RS12360	COG0511	ligase activity, forming carbon-carbon bonds
KM391_RS12365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM391_RS12370	COG1024	Enoyl-CoA hydratase
KM391_RS12375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM391_RS12380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM391_RS12390	COG1247	-acetyltransferase
KM391_RS12395	COG0572	uridine kinase
KM391_RS12405	COG2318	DinB family
KM391_RS12435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KM391_RS12475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM391_RS12475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM391_RS12500	COG2814	Major facilitator Superfamily
KM391_RS12520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM391_RS12540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS12555	COG1063	alcohol dehydrogenase
KM391_RS12570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM391_RS12575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM391_RS12590	COG3773	Cell wall hydrolase
KM391_RS12600	COG0745	RESPONSE REGULATOR receiver
KM391_RS12630	COG1136	(ABC) transporter
KM391_RS12655	COG0460	homoserine dehydrogenase
KM391_RS12660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS12670	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM391_RS12735	COG2124	cytochrome p450
KM391_RS12770	COG0561	phosphatase activity
KM391_RS12780	COG0768	penicillin binding
KM391_RS12785	COG1819	glycosyl
KM391_RS12790	COG1794	racemase activity, acting on amino acids and derivatives
KM391_RS12800	COG1122	ATPase activity
KM391_RS12815	COG2205	protein histidine kinase activity
KM391_RS12825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_RS12830	COG0604	alcohol dehydrogenase
KM391_RS12835	COG0768	penicillin binding
KM391_RS12845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_RS12880	COG0693	protein deglycase activity
KM391_RS12910	COG2814	Major facilitator Superfamily
KM391_RS12925	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_RS12945	COG0697	spore germination
KM391_RS12975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_RS12985	COG2223	nitrite transmembrane transporter activity
KM391_RS13000	COG2816	NAD+ diphosphatase activity
KM391_RS13005	COG0592	DNA-directed DNA polymerase activity
KM391_RS13010	COG1051	belongs to the nudix hydrolase family
KM391_RS13045	COG3878	Protein conserved in bacteria
KM391_RS13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM391_RS13110	COG0322	excinuclease ABC activity
KM391_RS13150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_RS13175	COG1011	Hydrolase
KM391_RS13195	COG0076	glutamate decarboxylase activity
KM391_RS13210	COG1523	belongs to the glycosyl hydrolase 13 family
KM391_RS13215	COG3227	Zinc metalloprotease (Elastase)
KM391_RS13235	COG0201	protein transport
KM391_RS13245	COG0697	spore germination
KM391_RS13250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS13280	COG4129	membrane
KM391_RS13285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS13300	COG2959	enzyme of heme biosynthesis
KM391_RS13320	COG3483	tryptophan 2,3-dioxygenase activity
KM391_RS13325	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KM391_RS13330	COG3844	kynureninase activity
KM391_RS13335	COG1309	transcriptional regulator
KM391_RS13365	COG3284	Transcriptional regulator
KM391_RS13385	COG1349	DNA-binding transcription factor activity
KM391_RS13405	COG1959	2 iron, 2 sulfur cluster binding
KM391_RS13420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM391_RS13425	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_RS13430	COG0022	dehydrogenase e1 component
KM391_RS13435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM391_RS13445	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS13450	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_RS13450	COG0456	acetyltransferase
KM391_RS13480	COG4176	ABC-type proline glycine betaine transport system permease component
KM391_RS13485	COG4175	Glycine betaine
KM391_RS13485	COG0517	IMP dehydrogenase activity
KM391_RS13510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KM391_RS13515	COG2153	protein acetylation
KM391_RS13520	COG3397	chitin binding
KM391_RS13535	COG2205	protein histidine kinase activity
KM391_RS13560	COG0658	competence protein
KM391_RS13560	COG2333	competence protein COMEC
KM391_RS13610	COG3973	AAA domain
KM391_RS13625	COG2105	PFAM AIG2 family protein
KM391_RS13630	COG0514	ATP-dependent DNA helicase (RecQ)
KM391_RS13650	COG4637	Psort location Cytoplasmic, score
KM391_RS13675	COG3397	chitin binding
KM391_RS13690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM391_RS13695	COG1115	amino acid carrier protein
KM391_RS13700	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS13705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM391_RS13715	COG3938	Belongs to the proline racemase family
KM391_RS13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM391_RS13760	COG0586	Pfam SNARE associated Golgi protein
KM391_RS13775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM391_RS13780	COG0519	Catalyzes the synthesis of GMP from XMP
KM391_RS13785	COG4166	transmembrane transport
KM391_RS13795	COG4948	Mandelate Racemase Muconate Lactonizing
KM391_RS13840	COG2936	dipeptidyl-peptidase activity
KM391_RS13845	COG5002	protein histidine kinase activity
KM391_RS13895	COG1307	EDD domain protein, DegV family
KM391_RS13915	COG2814	Major facilitator Superfamily
KM391_RS13925	COG1664	Polymer-forming cytoskeletal
KM391_RS13930	COG0789	Transcriptional regulator
KM391_RS13935	COG4533	DNA binding
KM391_RS13940	COG0477	Major facilitator Superfamily
KM391_RS13940	COG2814	Major facilitator Superfamily
KM391_RS13960	COG2261	transglycosylase associated protein
KM391_RS13975	COG2226	methyltransferase
KM391_RS14010	COG0436	Aminotransferase
KM391_RS14015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM391_RS14020	COG5146	pantothenate kinase activity
KM391_RS14085	COG0628	permease
KM391_RS14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM391_RS14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_RS14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM391_RS14115	COG1116	anion transmembrane transporter activity
KM391_RS14135	COG2816	NAD+ diphosphatase activity
KM391_RS14155	COG2746	aminoglycoside 3-N-acetyltransferase activity
KM391_RS14180	COG0697	spore germination
KM391_RS14185	COG2318	DinB family
KM391_RS14205	COG4912	Dna alkylation repair
KM391_RS14225	COG0861	Integral membrane protein TerC family
KM391_RS14230	COG1368	sulfuric ester hydrolase activity
KM391_RS14235	COG0488	(ABC) transporter
KM391_RS14250	COG1309	transcriptional regulator
KM391_RS14265	COG0287	Prephenate dehydrogenase
KM391_RS14270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KM391_RS14275	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KM391_RS14280	COG1605	Chorismate mutase
KM391_RS14280	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM391_RS14315	COG3584	3D domain protein
KM391_RS14315	COG1388	LysM domain
KM391_RS14325	COG1595	DNA-templated transcription, initiation
KM391_RS14350	COG1879	ABC-type sugar transport system periplasmic component
KM391_RS14360	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM391_RS14370	COG2390	Transcriptional regulator
KM391_RS14405	COG2329	Antibiotic biosynthesis monooxygenase
KM391_RS14425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS14435	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM391_RS14440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_RS14445	COG4187	Peptidase family M20/M25/M40
KM391_RS14450	COG1414	Transcriptional regulator
KM391_RS14455	COG0833	amino acid
KM391_RS14460	COG1690	Belongs to the RtcB family
KM391_RS14470	COG1785	Belongs to the alkaline phosphatase family
KM391_RS14480	COG3655	Transcriptional regulator
KM391_RS14495	COG4377	Putative membrane peptidase family (DUF2324)
KM391_RS14505	COG3279	Response regulator of the LytR AlgR family
KM391_RS14515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS14520	COG0346	lactoylglutathione lyase activity
KM391_RS14540	COG0714	Associated with various cellular activities
KM391_RS14565	COG0463	Glycosyl transferase, family 2
KM391_RS14585	COG0463	Glycosyl transferase, family 2
KM391_RS14595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM391_RS14600	COG0753	catalase activity
KM391_RS14610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM391_RS14635	COG0714	Associated with various cellular activities
KM391_RS14645	COG0778	Nitroreductase
KM391_RS14650	COG1846	Transcriptional regulator
KM391_RS14685	COG1725	Transcriptional regulator
KM391_RS14695	COG0577	efflux transmembrane transporter activity
KM391_RS14695	COG1136	(ABC) transporter
KM391_RS14720	COG2207	Transcriptional regulator
KM391_RS14725	COG0456	acetyltransferase
KM391_RS14745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS14765	COG0642	Histidine kinase
KM391_RS14770	COG0745	RESPONSE REGULATOR receiver
KM391_RS14775	COG0596	Alpha beta hydrolase
KM391_RS14805	COG0730	response to heat
KM391_RS14815	COG0833	amino acid
KM391_RS14825	COG4335	DNA alkylation repair
KM391_RS14865	COG0768	penicillin binding
KM391_RS14875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM391_RS14910	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM391_RS14915	COG1414	Transcriptional regulator
KM391_RS14930	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM391_RS14935	COG0640	Transcriptional regulator
KM391_RS14945	COG1960	acyl-CoA dehydrogenase activity
KM391_RS14960	COG3314	Sporulation integral membrane protein YlbJ
KM391_RS14975	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM391_RS14990	COG0574	Belongs to the PEP-utilizing enzyme family
KM391_RS14990	COG3848	Pyruvate phosphate dikinase
KM391_RS14995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS15010	COG5577	PFAM Coat F domain
KM391_RS15015	COG3403	YqcI/YcgG family
KM391_RS15020	COG1280	lysine exporter protein (LysE YggA)
KM391_RS15055	COG1063	alcohol dehydrogenase
KM391_RS15070	COG1027	Aspartate ammonia-lyase
KM391_RS15075	COG0252	asparaginase activity
KM391_RS15080	COG1396	sequence-specific DNA binding
KM391_RS15090	COG0322	excinuclease ABC activity
KM391_RS15095	COG0531	amino acid
KM391_RS15100	COG1114	Component of the transport system for branched-chain amino acids
KM391_RS15105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_RS15115	COG0281	malic enzyme
KM391_RS15130	COG0531	amino acid
KM391_RS15140	COG0784	Response regulator, receiver
KM391_RS15150	COG2066	Belongs to the glutaminase family
KM391_RS15185	COG0737	Belongs to the 5'-nucleotidase family
KM391_RS15190	COG0753	catalase activity
KM391_RS15200	COG1335	isochorismatase
KM391_RS15220	COG0583	DNA-binding transcription factor activity
KM391_RS15270	COG0415	Belongs to the DNA photolyase family
KM391_RS15275	COG0288	reversible hydration of carbon dioxide
KM391_RS15285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM391_RS15290	COG5609	conserved protein (DUF2294)
KM391_RS15305	COG1575	Belongs to the MenA family. Type 1 subfamily
KM391_RS15310	COG2267	carboxylic ester hydrolase activity
KM391_RS15315	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM391_RS15320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM391_RS15325	COG1121	(ABC) transporter
KM391_RS15355	COG0798	PFAM Bile acid sodium symporter
KM391_RS15360	COG0346	lactoylglutathione lyase activity
KM391_RS15365	COG0640	Transcriptional regulator
KM391_RS15380	COG0443	Heat shock 70 kDa protein
KM391_RS15395	COG1522	sequence-specific DNA binding
KM391_RS15410	COG0346	lactoylglutathione lyase activity
KM391_RS15430	COG2169	Transcriptional regulator
KM391_RS15435	COG2169	Transcriptional regulator
KM391_RS15480	COG2814	Major facilitator Superfamily
KM391_RS15505	COG0745	RESPONSE REGULATOR receiver
KM391_RS15510	COG3850	Histidine kinase
KM391_RS15510	COG5002	protein histidine kinase activity
KM391_RS15535	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KM391_RS15555	COG1476	TRANSCRIPTIONal
KM391_RS15570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS15575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM391_RS15585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_RS15590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KM391_RS15605	COG1136	(ABC) transporter
KM391_RS15610	COG0577	efflux transmembrane transporter activity
KM391_RS15625	COG3850	Histidine kinase
KM391_RS15625	COG5002	protein histidine kinase activity
KM391_RS15635	COG2364	Membrane
KM391_RS15640	COG1846	Transcriptional regulator
KM391_RS15650	COG2808	Putative FMN-binding domain
KM391_RS15655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS15660	COG2271	Major facilitator Superfamily
KM391_RS15665	COG1556	Lactate utilization protein
KM391_RS15670	COG1139	Iron-sulfur cluster binding protein
KM391_RS15680	COG0583	DNA-binding transcription factor activity
KM391_RS15690	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM391_RS15710	COG0738	Major facilitator superfamily
KM391_RS15715	COG0673	inositol 2-dehydrogenase activity
KM391_RS15720	COG0561	phosphatase activity
KM391_RS15730	COG1609	Transcriptional regulator
KM391_RS15735	COG0457	Tetratricopeptide repeat
KM391_RS15755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM391_RS15785	COG0534	Mate efflux family protein
KM391_RS15805	COG2814	Major facilitator Superfamily
KM391_RS15810	COG1309	transcriptional regulator
KM391_RS15825	COG0814	amino acid
KM391_RS15830	COG1760	l-serine dehydratase
KM391_RS15835	COG1760	l-serine dehydratase
KM391_RS15845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM391_RS15850	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
KM391_RS15860	COG1335	isochorismatase
KM391_RS15865	COG1522	sequence-specific DNA binding
KM391_RS15870	COG0531	amino acid
KM391_RS15890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM391_RS15910	COG1595	DNA-templated transcription, initiation
KM391_RS15925	COG0662	Cupin 2, conserved barrel domain protein
KM391_RS15930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_RS15930	COG2207	Transcriptional regulator
KM391_RS15980	COG0477	Major facilitator Superfamily
KM391_RS15990	COG1846	Transcriptional regulator
KM391_RS15995	COG2814	Major facilitator Superfamily
KM391_RS16005	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM391_RS16010	COG1131	(ABC) transporter
KM391_RS16030	COG2076	Multidrug Resistance protein
KM391_RS16035	COG1309	transcriptional regulator
KM391_RS16045	COG2031	fatty acid transporter
KM391_RS16055	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM391_RS16085	COG1122	ATPase activity
KM391_RS16090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM391_RS16105	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KM391_RS16110	COG1288	antiporter activity
KM391_RS16115	COG2356	endonuclease I
KM391_RS16130	COG3620	sequence-specific DNA binding
KM391_RS16135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM391_RS16140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM391_RS16145	COG0124	histidyl-tRNA synthetase
KM391_RS16160	COG1733	regulation of RNA biosynthetic process
KM391_RS16165	COG0778	Nitroreductase
KM391_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS16195	COG1131	(ABC) transporter
KM391_RS16220	COG1011	Hydrolase
KM391_RS16230	COG2365	Tyrosine phosphatase family
KM391_RS16255	COG0346	lactoylglutathione lyase activity
KM391_RS16260	COG1940	carbohydrate kinase activity
KM391_RS16265	COG0738	Major facilitator superfamily
KM391_RS16270	COG0110	maltose O-acetyltransferase activity
KM391_RS16280	COG0577	efflux transmembrane transporter activity
KM391_RS16280	COG1136	(ABC) transporter
KM391_RS16295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KM391_RS16300	COG0628	permease
KM391_RS16320	COG2226	methyltransferase
KM391_RS16330	COG0477	Major facilitator Superfamily
KM391_RS16360	COG1253	flavin adenine dinucleotide binding
KM391_RS16365	COG0789	Transcriptional regulator
KM391_RS16370	COG0697	spore germination
KM391_RS16375	COG1357	PFAM Pentapeptide repeats (8 copies)
KM391_RS16380	COG3813	Protein conserved in bacteria
KM391_RS16385	COG2706	6-phosphogluconolactonase activity
KM391_RS16390	COG1070	Carbohydrate kinase
KM391_RS16400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KM391_RS16405	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KM391_RS16415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM391_RS16420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM391_RS16425	COG0604	alcohol dehydrogenase
KM391_RS16430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM391_RS16440	COG3321	synthase
KM391_RS16440	COG0604	alcohol dehydrogenase
KM391_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS16470	COG0656	L-ascorbic acid biosynthetic process
KM391_RS16475	COG2814	Major facilitator Superfamily
KM391_RS16490	COG0346	lactoylglutathione lyase activity
KM391_RS16495	COG0814	amino acid
KM391_RS16520	COG1393	Belongs to the ArsC family
KM391_RS16525	COG1733	regulation of RNA biosynthetic process
KM391_RS16530	COG2188	Transcriptional regulator
KM391_RS16540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KM391_RS16545	COG1733	regulation of RNA biosynthetic process
KM391_RS16550	COG1733	regulation of RNA biosynthetic process
KM391_RS16565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS16585	COG0384	phenazine biosynthesis protein PhzF
KM391_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS16605	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_RS16615	COG1733	regulation of RNA biosynthetic process
KM391_RS16645	COG1191	sigma factor activity
KM391_RS16660	COG1309	transcriptional regulator
KM391_RS16680	COG3152	Membrane
KM391_RS16705	COG1151	hydroxylamine reductase activity
KM391_RS16715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS16720	COG3409	Peptidoglycan-binding domain 1 protein
KM391_RS16720	COG3757	hydrolase, family 25
KM391_RS16755	COG2072	flavoprotein involved in K transport
KM391_RS16795	COG1113	amino acid transport
KM391_RS16800	COG2814	Major facilitator Superfamily
KM391_RS16830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM391_RS16835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM391_RS16860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS16865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS16870	COG3739	integral membrane protein
KM391_RS16875	COG0384	phenazine biosynthesis protein PhzF
KM391_RS16905	COG0583	DNA-binding transcription factor activity
KM391_RS16925	COG1193	negative regulation of DNA recombination
KM391_RS16945	COG1164	Oligoendopeptidase f
KM391_RS16950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM391_RS16980	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_RS17005	COG0640	Transcriptional regulator
KM391_RS17010	COG0604	alcohol dehydrogenase
KM391_RS17030	COG2808	Putative FMN-binding domain
KM391_RS17035	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_RS17045	COG0385	Bile acid
KM391_RS17050	COG0277	FAD linked oxidase domain protein
KM391_RS17080	COG1216	Glycosyl transferase, family 2
KM391_RS17085	COG1024	Enoyl-CoA hydratase
KM391_RS17095	COG1285	pathogenesis
KM391_RS17110	COG2514	catechol 2,3-dioxygenase activity
KM391_RS17115	COG2720	vancomycin resistance protein
KM391_RS17155	COG0716	FMN binding
KM391_RS17185	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS17195	COG0165	Argininosuccinate lyase
KM391_RS17210	COG4145	pantothenate transmembrane transporter activity
KM391_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS17225	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS17235	COG1657	PFAM Prenyltransferase squalene oxidase
KM391_RS17240	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM391_RS17245	COG2962	Rard protein
KM391_RS17250	COG3326	Membrane
KM391_RS17265	COG0489	protein tyrosine kinase activity
KM391_RS17275	COG0314	molybdopterin synthase activity
KM391_RS17280	COG0303	'Molybdopterin
KM391_RS17285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_RS17290	COG2116	formate transmembrane transporter activity
KM391_RS17305	COG5609	conserved protein (DUF2294)
KM391_RS17310	COG2427	Protein of unknown function (DUF1641)
KM391_RS17315	COG3383	formate dehydrogenase (NAD+) activity
KM391_RS17325	COG0697	spore germination
KM391_RS17365	COG2226	methyltransferase
KM391_RS17370	COG4166	transmembrane transport
KM391_RS17375	COG4166	transmembrane transport
KM391_RS17380	COG4166	transmembrane transport
KM391_RS17385	COG1301	dicarboxylic acid transport
KM391_RS17390	COG1316	TRANSCRIPTIONal
KM391_RS17400	COG1595	DNA-templated transcription, initiation
KM391_RS17420	COG1131	(ABC) transporter
KM391_RS17430	COG0673	inositol 2-dehydrogenase activity
KM391_RS17435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM391_RS17440	COG0187	DNA topoisomerase II activity
KM391_RS17445	COG1832	CoA-binding protein
KM391_RS17450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM391_RS17455	COG0745	RESPONSE REGULATOR receiver
KM391_RS17470	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KM391_RS17475	COG4841	protein insertion into membrane
KM391_RS17480	COG0824	Thioesterase
KM391_RS17510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_RS17520	COG2274	protein secretion by the type I secretion system
KM391_RS17525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM391_RS17565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM391_RS17580	COG0183	Belongs to the thiolase family
KM391_RS17585	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_RS17590	COG1268	BioY protein
KM391_RS17595	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_RS17645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS17655	COG5002	protein histidine kinase activity
KM391_RS17660	COG0400	carboxylic ester hydrolase activity
KM391_RS17665	COG0346	lactoylglutathione lyase activity
KM391_RS17670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM391_RS17675	COG0069	glutamate synthase activity
KM391_RS17680	COG1902	pentaerythritol trinitrate reductase activity
KM391_RS17685	COG1329	Transcriptional regulator
KM391_RS17690	COG0010	Belongs to the arginase family
KM391_RS17715	COG2226	methyltransferase
KM391_RS17750	COG4846	Membrane protein involved in cytochrome C biogenesis
KM391_RS17755	COG0785	Cytochrome C biogenesis protein
KM391_RS17765	COG0583	DNA-binding transcription factor activity
KM391_RS17770	COG1380	Effector of murein hydrolase LrgA
KM391_RS17775	COG1346	cytolysis
KM391_RS17800	COG3409	Peptidoglycan-binding domain 1 protein
KM391_RS17800	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM391_RS17815	COG1132	(ABC) transporter
KM391_RS17820	COG1132	(ABC) transporter
KM391_RS17850	COG3639	organic phosphonate transmembrane transporter activity
KM391_RS17855	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KM391_RS17875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM391_RS17895	COG1695	Transcriptional regulator
KM391_RS17935	COG1388	LysM domain
KM391_RS17935	COG3409	Peptidoglycan-binding domain 1 protein
KM391_RS17935	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM391_RS17940	COG4824	toxin secretion phage lysis holin
KM391_RS18095	COG1595	DNA-templated transcription, initiation
KM391_RS18140	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KM391_RS18220	COG1396	sequence-specific DNA binding
KM391_RS18245	COG0174	glutamine synthetase
KM391_RS18250	COG0789	Transcriptional regulator
KM391_RS18255	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM391_RS18265	COG2860	membrane
KM391_RS18270	COG0464	growth
KM391_RS18300	COG3584	3D domain protein
KM391_RS18300	COG1388	LysM domain
KM391_RS18305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM391_RS18305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM391_RS18305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM391_RS18310	COG1105	Belongs to the carbohydrate kinase PfkB family
KM391_RS18315	COG1349	DNA-binding transcription factor activity
KM391_RS18325	COG2322	membrane
KM391_RS18335	COG1113	amino acid transport
KM391_RS18350	COG1408	metallophosphoesterase
KM391_RS18355	COG2116	formate transmembrane transporter activity
KM391_RS18365	COG2217	Heavy metal translocating P-type atpase
KM391_RS18370	COG2608	mercury ion transmembrane transporter activity
KM391_RS18375	COG1937	Protein conserved in bacteria
KM391_RS18385	COG2819	hydrolase of the alpha beta superfamily
KM391_RS18390	COG1120	ATPase activity
KM391_RS18395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS18410	COG0708	Exodeoxyribonuclease III
KM391_RS18415	COG2169	Transcriptional regulator
KM391_RS18420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM391_RS18425	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM391_RS18435	COG2364	Membrane
KM391_RS18450	COG2267	carboxylic ester hydrolase activity
KM391_RS18455	COG0346	lactoylglutathione lyase activity
KM391_RS18460	COG3300	MHYT domain
KM391_RS18460	COG5001	Diguanylate cyclase
KM391_RS18475	COG1346	cytolysis
KM391_RS18480	COG1380	Effector of murein hydrolase LrgA
KM391_RS18485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM391_RS18490	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_RS18490	COG0596	Alpha beta hydrolase
KM391_RS18495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM391_RS18515	COG1404	Belongs to the peptidase S8 family
KM391_RS18520	COG3773	Cell wall hydrolase
KM391_RS18525	COG0562	UDP-galactopyranose mutase
KM391_RS18530	COG1368	sulfuric ester hydrolase activity
KM391_RS18535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM391_RS18545	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM391_RS18570	COG1131	(ABC) transporter
KM391_RS18590	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM391_RS18595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM391_RS18600	COG1013	pyruvate-flavodoxin oxidoreductase activity
KM391_RS18605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KM391_RS18605	COG0674	pyruvate-flavodoxin oxidoreductase activity
KM391_RS18615	COG2359	stage V sporulation protein S
KM391_RS18620	COG1692	metallophosphoesterase
KM391_RS18645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM391_RS18650	COG1426	Protein conserved in bacteria
KM391_RS18665	COG0300	oxidoreductase activity
KM391_RS18670	COG0612	Peptidase, M16
KM391_RS18675	COG0612	Peptidase, M16
KM391_RS18690	COG3845	ABC transporter
KM391_RS18695	COG1744	ABC transporter substrate-binding protein PnrA-like
KM391_RS18700	COG2188	Transcriptional regulator
KM391_RS18705	COG1674	ftsk spoiiie
KM391_RS18715	COG0740	serine-type endopeptidase activity
KM391_RS18720	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM391_RS18730	COG0527	aspartate kinase activity
KM391_RS18735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM391_RS18740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM391_RS18745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM391_RS18750	COG1873	PFAM PRC-barrel domain
KM391_RS18755	COG0612	Peptidase, M16
KM391_RS18760	COG0726	polysaccharide deacetylase
KM391_RS18775	COG0196	riboflavin kinase activity
KM391_RS18780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KM391_RS18790	COG1550	Protein conserved in bacteria
KM391_RS18800	COG1358	cellular component organization or biogenesis
KM391_RS18805	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM391_RS18810	COG0195	Participates in both transcription termination and antitermination
KM391_RS18830	COG0750	zinc metalloprotease
KM391_RS18840	COG4589	Belongs to the CDS family
KM391_RS18845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM391_RS18855	COG0528	UMP kinase activity
KM391_RS18885	COG4974	Belongs to the 'phage' integrase family
KM391_RS18895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM391_RS18905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM391_RS18945	COG1837	Belongs to the UPF0109 family
KM391_RS18955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM391_RS18965	COG0552	protein localization to endoplasmic reticulum
KM391_RS18970	COG1196	nuclear chromosome segregation
KM391_RS18980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM391_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS18990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM391_RS19005	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM391_RS19010	COG1461	Dihydroxyacetone kinase
KM391_RS19015	COG1302	Protein conserved in bacteria
KM391_RS19030	COG1564	THIamine pyrophosphokinase
KM391_RS19035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM391_RS19040	COG1162	GTPase activity
KM391_RS19045	COG0515	serine threonine protein kinase
KM391_RS19045	COG2815	serine threonine protein kinase
KM391_RS19050	COG0631	protein serine/threonine phosphatase activity
KM391_RS19060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM391_RS19060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM391_RS19070	COG0242	peptide deformylase activity
KM391_RS19075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM391_RS19080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM391_RS19100	COG1561	YicC-like family, N-terminal region
KM391_RS19105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM391_RS19115	COG0006	proline dipeptidase activity
KM391_RS19130	COG3069	C4-dicarboxylate transmembrane transporter activity
KM391_RS19195	COG0564	pseudouridine synthase activity
KM391_RS19215	COG3599	regulation of cell shape
KM391_RS19220	COG2302	S4 RNA-binding domain
KM391_RS19225	COG0762	integral membrane protein
KM391_RS19235	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM391_RS19240	COG1496	oxidoreductase activity
KM391_RS19245	COG1873	PFAM PRC-barrel domain
KM391_RS19250	COG1191	sigma factor activity
KM391_RS19255	COG1191	sigma factor activity
KM391_RS19265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM391_RS19270	COG0849	cell division
KM391_RS19275	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM391_RS19280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM391_RS19290	COG0772	Belongs to the SEDS family
KM391_RS19305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KM391_RS19310	COG0768	penicillin binding
KM391_RS19315	COG0768	penicillin binding
KM391_RS19320	COG4839	cell division protein FtsL
KM391_RS19335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM391_RS19350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KM391_RS19355	COG1399	metal-binding, possibly nucleic acid-binding protein
KM391_RS19405	COG4824	toxin secretion phage lysis holin
KM391_RS19505	COG1802	Transcriptional regulator
KM391_RS19505	COG4626	Terminase
KM391_RS19530	COG0582	viral genome integration into host DNA
KM391_RS19595	COG0756	dUTP diphosphatase activity
KM391_RS19610	COG1191	sigma factor activity
KM391_RS19635	COG1484	DNA-dependent DNA replication
KM391_RS19665	COG1396	sequence-specific DNA binding
KM391_RS19680	COG1396	sequence-specific DNA binding
KM391_RS19695	COG0582	viral genome integration into host DNA
KM391_RS19705	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM391_RS19710	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM391_RS19715	COG3314	Sporulation integral membrane protein YlbJ
KM391_RS19725	COG0742	ribosomal rna small subunit methyltransferase
KM391_RS19740	COG3679	Belongs to the UPF0342 family
KM391_RS19745	COG0406	alpha-ribazole phosphatase activity
KM391_RS19760	COG2340	Cysteine-rich secretory protein family
KM391_RS19775	COG3336	cytochrome c oxidase
KM391_RS19810	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM391_RS19815	COG0772	Belongs to the SEDS family
KM391_RS19825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM391_RS19830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM391_RS19840	COG4896	Protein conserved in bacteria
KM391_RS19855	COG1217	gtp-binding protein TYPA
KM391_RS19865	COG0483	inositol monophosphate 1-phosphatase activity
KM391_RS19885	COG1982	Orn Lys Arg decarboxylase major
KM391_RS19930	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_RS19935	COG0022	dehydrogenase e1 component
KM391_RS19940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM391_RS19950	COG0242	peptide deformylase activity
KM391_RS19955	COG0561	phosphatase activity
KM391_RS19965	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM391_RS19970	COG0569	domain protein
KM391_RS19990	COG0583	DNA-binding transcription factor activity
KM391_RS19995	COG0517	IMP dehydrogenase activity
KM391_RS20005	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM391_RS20015	COG4703	Protein of unknown function (DUF1797)
KM391_RS20030	COG2200	EAL domain
KM391_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS20040	COG1408	metallophosphoesterase
KM391_RS20050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KM391_RS20085	COG2814	Major facilitator Superfamily
KM391_RS20105	COG3209	COG3209 Rhs family protein
KM391_RS20115	COG2205	protein histidine kinase activity
KM391_RS20125	COG0436	Aminotransferase
KM391_RS20130	COG1609	Transcriptional regulator
KM391_RS20135	COG3833	ABC-type maltose transport systems, permease component
KM391_RS20140	COG1175	transmembrane transport
KM391_RS20145	COG2182	Extracellular solute-binding protein
KM391_RS20155	COG0366	Alpha amylase catalytic
KM391_RS20160	COG3842	ATPase activity
KM391_RS20200	COG0183	Belongs to the thiolase family
KM391_RS20235	COG1695	Transcriptional regulator
KM391_RS20240	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS20250	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KM391_RS20260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM391_RS20265	COG0436	Aminotransferase
KM391_RS20285	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KM391_RS20305	COG2199	diguanylate cyclase activity
KM391_RS20310	COG0778	Nitroreductase
KM391_RS20335	COG1263	PTS System
KM391_RS20335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM391_RS20335	COG2190	(PTS) system
KM391_RS20340	COG3711	transcriptional antiterminator
KM391_RS20350	COG2188	Transcriptional regulator
KM391_RS20360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM391_RS20385	COG1547	Domain of unknown function (DUF309)
KM391_RS20390	COG0456	acetyltransferase
KM391_RS20400	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM391_RS20405	COG4086	secreted protein
KM391_RS20410	COG0561	phosphatase activity
KM391_RS20415	COG0697	spore germination
KM391_RS20430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_RS20455	COG0733	neurotransmitter:sodium symporter activity
KM391_RS20475	COG1686	Belongs to the peptidase S11 family
KM391_RS20480	COG1725	Transcriptional regulator
KM391_RS20485	COG1131	(ABC) transporter
KM391_RS20500	COG1846	Transcriptional regulator
KM391_RS20515	COG0598	Magnesium transport protein CorA
KM391_RS20540	COG4974	Belongs to the 'phage' integrase family
KM391_RS20550	COG0735	belongs to the Fur family
KM391_RS20555	COG1300	Membrane
KM391_RS20575	COG0667	Aldo Keto reductase
KM391_RS20580	COG0656	L-ascorbic acid biosynthetic process
KM391_RS20585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM391_RS20585	COG0456	acetyltransferase
KM391_RS20595	COG0737	Belongs to the 5'-nucleotidase family
KM391_RS20595	COG1525	nuclease
KM391_RS20595	COG4085	toxin activity
KM391_RS20605	COG0596	Alpha beta hydrolase
KM391_RS20610	COG2056	Na+-H+ antiporter family
KM391_RS20615	COG1609	Transcriptional regulator
KM391_RS20620	COG0456	acetyltransferase
KM391_RS20625	COG1073	alpha beta
KM391_RS20640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM391_RS20640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM391_RS20645	COG0307	riboflavin synthase, alpha
KM391_RS20670	COG4106	trans-aconitate 2-methyltransferase activity
KM391_RS20675	COG1073	alpha beta
KM391_RS20675	COG2226	methyltransferase
KM391_RS20690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM391_RS20700	COG1757	Na H antiporter
KM391_RS20705	COG0737	Belongs to the 5'-nucleotidase family
KM391_RS20715	COG1522	sequence-specific DNA binding
KM391_RS20735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM391_RS20745	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM391_RS20760	COG0300	oxidoreductase activity
KM391_RS20770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_RS20775	COG1760	l-serine dehydratase
KM391_RS20780	COG1760	l-serine dehydratase
KM391_RS20800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM391_RS20810	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM391_RS20815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS20830	COG1376	ErfK ybiS ycfS ynhG family protein
KM391_RS20835	COG4129	membrane
KM391_RS20840	COG1126	abc transporter atp-binding protein
KM391_RS20845	COG0765	amino acid transport
KM391_RS20850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM391_RS20865	COG2816	NAD+ diphosphatase activity
KM391_RS20870	COG0772	Belongs to the SEDS family
KM391_RS20875	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM391_RS20880	COG0022	dehydrogenase e1 component
KM391_RS20885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM391_RS20890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM391_RS20905	COG0280	phosphate acetyltransferase
KM391_RS20910	COG3829	transcription factor binding
KM391_RS20910	COG3290	protein histidine kinase activity
KM391_RS20920	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_RS20925	COG3093	addiction module antidote protein HigA
KM391_RS20935	COG0745	RESPONSE REGULATOR receiver
KM391_RS20940	COG0750	zinc metalloprotease
KM391_RS20945	COG0497	DNA recombination
KM391_RS20955	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM391_RS20965	COG0142	geranyltranstransferase activity
KM391_RS20990	COG1302	Protein conserved in bacteria
KM391_RS20995	COG0439	Biotin carboxylase
KM391_RS21000	COG0511	ligase activity, forming carbon-carbon bonds
KM391_RS21045	COG3854	ATPases associated with a variety of cellular activities
KM391_RS21070	COG0006	proline dipeptidase activity
KM391_RS21085	COG3872	metal-dependent enzyme
KM391_RS21095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM391_RS21115	COG0095	Lipoate-protein ligase
KM391_RS21120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_RS21125	COG1609	Transcriptional regulator
KM391_RS21135	COG2076	Multidrug Resistance protein
KM391_RS21140	COG2076	Multidrug Resistance protein
KM391_RS21175	COG1131	(ABC) transporter
KM391_RS21180	COG1725	Transcriptional regulator
KM391_RS21210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM391_RS21265	COG4970	Tfp pilus assembly protein FimT
KM391_RS21275	COG1459	type II secretion system
KM391_RS21280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM391_RS21330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM391_RS21335	COG0646	methionine synthase
KM391_RS21335	COG1410	methionine synthase
KM391_RS21340	COG0646	methionine synthase
KM391_RS21340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM391_RS21345	COG0626	cystathionine gamma-synthase activity
KM391_RS21350	COG0626	cystathionine gamma-synthase activity
KM391_RS21370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS21380	COG1940	carbohydrate kinase activity
KM391_RS21385	COG4483	Protein conserved in bacteria
KM391_RS21390	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM391_RS21395	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KM391_RS21400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM391_RS21405	COG0704	Plays a role in the regulation of phosphate uptake
KM391_RS21415	COG0581	inorganic phosphate transmembrane transporter activity
KM391_RS21420	COG0573	inorganic phosphate transmembrane transporter activity
KM391_RS21425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM391_RS21430	COG0768	penicillin binding
KM391_RS21435	COG0477	Major facilitator Superfamily
KM391_RS21440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM391_RS21465	COG0735	belongs to the Fur family
KM391_RS21470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM391_RS21475	COG1121	(ABC) transporter
KM391_RS21480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS21510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM391_RS21515	COG2384	SAM-dependent methyltransferase
KM391_RS21520	COG2010	Cytochrome c
KM391_RS21525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM391_RS21530	COG0358	DNA primase activity
KM391_RS21540	COG0517	IMP dehydrogenase activity
KM391_RS21555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM391_RS21560	COG0295	cytidine deaminase activity
KM391_RS21565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM391_RS21575	COG1480	7TM receptor with intracellular HD hydrolase
KM391_RS21580	COG1702	phosphate starvation-inducible protein PhoH
KM391_RS21595	COG1610	YqeY-like protein
KM391_RS21600	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KM391_RS21605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM391_RS21610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM391_RS21640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM391_RS21645	COG1733	regulation of RNA biosynthetic process
KM391_RS21670	COG1466	dna polymerase III delta subunit
KM391_RS21680	COG2333	competence protein COMEC
KM391_RS21680	COG0658	competence protein
KM391_RS21685	COG2131	deaminase
KM391_RS21690	COG1596	polysaccharide export
KM391_RS21690	COG1555	photosystem II stabilization
KM391_RS21695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM391_RS21700	COG2226	methyltransferase
KM391_RS21705	COG0799	negative regulation of ribosome biogenesis
KM391_RS21710	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM391_RS21720	COG1534	Rna-binding protein
KM391_RS21730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM391_RS21735	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM391_RS21760	COG1595	DNA-templated transcription, initiation
KM391_RS21770	COG0778	Nitroreductase
KM391_RS21775	COG2357	RelA SpoT domain protein
KM391_RS21785	COG1785	Belongs to the alkaline phosphatase family
KM391_RS21795	COG2267	carboxylic ester hydrolase activity
KM391_RS21830	COG1404	Belongs to the peptidase S8 family
KM391_RS21835	COG3186	Phenylalanine-4-hydroxylase
KM391_RS21850	COG2259	Doxx family
KM391_RS21890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_RS21900	COG1012	belongs to the aldehyde dehydrogenase family
KM391_RS21900	COG1454	alcohol dehydrogenase
KM391_RS21905	COG0626	cystathionine gamma-synthase activity
KM391_RS21910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM391_RS21935	COG0768	penicillin binding
KM391_RS21950	COG0826	peptidase U32
KM391_RS21955	COG0826	peptidase U32
KM391_RS21960	COG4122	O-methyltransferase activity
KM391_RS21965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM391_RS21985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KM391_RS21995	COG0628	permease
KM391_RS22015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM391_RS22025	COG0482	sulfurtransferase activity
KM391_RS22030	COG1104	cysteine desulfurase activity
KM391_RS22035	COG1959	2 iron, 2 sulfur cluster binding
KM391_RS22040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM391_RS22050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM391_RS22075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM391_RS22085	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM391_RS22085	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM391_RS22090	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM391_RS22095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM391_RS22095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM391_RS22105	COG2244	polysaccharide biosynthetic process
KM391_RS22110	COG2323	membrane
KM391_RS22120	COG1862	Preprotein translocase
KM391_RS22150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM391_RS22160	COG0697	spore germination
KM391_RS22165	COG0697	spore germination
KM391_RS22170	COG0640	Transcriptional regulator
KM391_RS22195	COG0157	Belongs to the NadC ModD family
KM391_RS22200	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM391_RS22205	COG1104	cysteine desulfurase activity
KM391_RS22210	COG1827	regulation of RNA biosynthetic process
KM391_RS22215	COG2258	MOSC domain
KM391_RS22220	COG0077	Prephenate dehydratase
KM391_RS22225	COG0577	efflux transmembrane transporter activity
KM391_RS22230	COG0577	efflux transmembrane transporter activity
KM391_RS22235	COG1136	(ABC) transporter
KM391_RS22245	COG0745	RESPONSE REGULATOR receiver
KM391_RS22250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KM391_RS22255	COG3290	protein histidine kinase activity
KM391_RS22265	COG2868	ribosomal protein
KM391_RS22275	COG1530	ribonuclease E activity
KM391_RS22280	COG1994	Peptidase M50
KM391_RS22285	COG0739	heme binding
KM391_RS22290	COG2894	cell division
KM391_RS22310	COG1077	Cell shape determining protein MreB Mrl
KM391_RS22330	COG0285	dihydrofolate synthase activity
KM391_RS22335	COG0525	valine-tRNA ligase activity
KM391_RS22345	COG1388	LysM domain
KM391_RS22355	COG0113	porphobilinogen synthase activity
KM391_RS22360	COG1587	Uroporphyrinogen-III synthase
KM391_RS22370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM391_RS22380	COG1846	Transcriptional regulator
KM391_RS22385	COG1764	response to oxidative stress
KM391_RS22400	COG1067	ATP-dependent peptidase activity
KM391_RS22400	COG0470	DNA polymerase III
KM391_RS22445	COG0622	Phosphoesterase
KM391_RS22460	COG5401	PFAM Sporulation and spore germination
KM391_RS22480	COG1309	transcriptional regulator
KM391_RS22495	COG2197	response regulator
KM391_RS22500	COG2233	PERMEase
KM391_RS22510	COG0402	S-adenosylhomocysteine deaminase activity
KM391_RS22515	COG0402	S-adenosylhomocysteine deaminase activity
KM391_RS22525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM391_RS22535	COG0444	Belongs to the ABC transporter superfamily
KM391_RS22540	COG4608	Belongs to the ABC transporter superfamily
KM391_RS22545	COG3275	phosphorelay sensor kinase activity
KM391_RS22550	COG3279	Response regulator of the LytR AlgR family
KM391_RS22565	COG1983	PspC domain protein
KM391_RS22570	COG1396	sequence-specific DNA binding
KM391_RS22575	COG0697	spore germination
KM391_RS22585	COG1959	2 iron, 2 sulfur cluster binding
KM391_RS22590	COG1668	transmembrane transport
KM391_RS22595	COG4152	abc transporter atp-binding protein
KM391_RS22600	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KM391_RS22610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM391_RS22615	COG1876	peptidase activity
KM391_RS22620	COG0824	Thioesterase
KM391_RS22625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM391_RS22630	COG1053	succinate dehydrogenase
KM391_RS22635	COG2009	succinate dehydrogenase
KM391_RS22640	COG1719	4-vinyl reductase, 4VR
KM391_RS22650	COG3118	belongs to the thioredoxin family
KM391_RS22655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM391_RS22660	COG2086	electron transfer activity
KM391_RS22665	COG1024	Enoyl-CoA hydratase
KM391_RS22675	COG0318	PFAM AMP-dependent synthetase and ligase
KM391_RS22695	COG2318	DinB family
KM391_RS22725	COG1131	(ABC) transporter
KM391_RS22730	COG2205	protein histidine kinase activity
KM391_RS22735	COG0745	RESPONSE REGULATOR receiver
KM391_RS22745	COG4895	conserved protein (DUF2196)
KM391_RS22750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM391_RS22765	COG4509	Sortase family
KM391_RS22770	COG1120	ATPase activity
KM391_RS22785	COG5386	Cell surface protein
KM391_RS22795	COG5386	Cell surface protein
KM391_RS22800	COG1114	Component of the transport system for branched-chain amino acids
KM391_RS22805	COG1187	pseudouridine synthase activity
KM391_RS22815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM391_RS22815	COG1796	DNA polymerase
KM391_RS22820	COG1286	toxin biosynthetic process
KM391_RS22865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM391_RS22875	COG1418	mRNA catabolic process
KM391_RS22900	COG2814	Major facilitator Superfamily
KM391_RS22905	COG1566	PFAM secretion protein HlyD family protein
KM391_RS22910	COG1309	transcriptional regulator
KM391_RS22915	COG1363	Peptidase, m42
KM391_RS22940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM391_RS22950	COG1484	DNA-dependent DNA replication
KM391_RS22955	COG3611	Membrane attachment protein
KM391_RS22965	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM391_RS22970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM391_RS22975	COG0237	dephospho-CoA kinase activity
KM391_RS22980	COG1971	Probably functions as a manganese efflux pump
KM391_RS22990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM391_RS22990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM391_RS22995	COG5002	protein histidine kinase activity
KM391_RS23000	COG0745	RESPONSE REGULATOR receiver
KM391_RS23020	COG0538	isocitrate dehydrogenase activity
KM391_RS23025	COG0372	Belongs to the citrate synthase family
KM391_RS23035	COG0628	permease
KM391_RS23040	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM391_RS23065	COG1725	Transcriptional regulator
KM391_RS23070	COG0281	malic enzyme
KM391_RS23075	COG0587	DNA-directed DNA polymerase activity
KM391_RS23090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM391_RS23110	COG4109	DRTGG domain
KM391_RS23125	COG0006	proline dipeptidase activity
KM391_RS23165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS23170	COG0662	Cupin 2, conserved barrel domain protein
KM391_RS23180	COG1476	TRANSCRIPTIONal
KM391_RS23195	COG1028	Short-chain dehydrogenase reductase Sdr
KM391_RS23200	COG0589	response to stress
KM391_RS23240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS23260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KM391_RS23265	COG0827	DNA restriction-modification system
KM391_RS23270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM391_RS23275	COG3874	Sporulation protein YtfJ
KM391_RS23290	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM391_RS23300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM391_RS23315	COG1104	cysteine desulfurase activity
KM391_RS23325	COG0583	DNA-binding transcription factor activity
KM391_RS23330	COG0697	spore germination
KM391_RS23340	COG1956	GAF domain-containing protein
KM391_RS23345	COG0626	cystathionine gamma-synthase activity
KM391_RS23375	COG1595	DNA-templated transcription, initiation
KM391_RS23385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM391_RS23390	COG0454	-acetyltransferase
KM391_RS23395	COG0517	IMP dehydrogenase activity
KM391_RS23400	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM391_RS23410	COG0745	RESPONSE REGULATOR receiver
KM391_RS23420	COG0666	response to abiotic stimulus
KM391_RS23455	COG1609	Transcriptional regulator
KM391_RS23460	COG4851	CamS sex pheromone cAM373 precursor
KM391_RS23465	COG3118	belongs to the thioredoxin family
KM391_RS23475	COG2309	aminopeptidase activity
KM391_RS23495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS23510	COG1674	ftsk spoiiie
KM391_RS23520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM391_RS23525	COG4848	Belongs to the UPF0354 family
KM391_RS23530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_RS23535	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KM391_RS23540	COG1363	Peptidase, m42
KM391_RS23550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS23565	COG0510	thiamine kinase activity
KM391_RS23570	COG1523	belongs to the glycosyl hydrolase 13 family
KM391_RS23585	COG1349	DNA-binding transcription factor activity
KM391_RS23590	COG1187	pseudouridine synthase activity
KM391_RS23595	COG2244	polysaccharide biosynthetic process
KM391_RS23600	COG2081	HI0933 family
KM391_RS23605	COG2814	Major facilitator Superfamily
KM391_RS23615	COG3832	glyoxalase III activity
KM391_RS23635	COG1329	Transcriptional regulator
KM391_RS23645	COG4975	Glucose uptake
KM391_RS23660	COG0314	molybdopterin synthase activity
KM391_RS23665	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM391_RS23670	COG0303	'Molybdopterin
KM391_RS23680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM391_RS23705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM391_RS23715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KM391_RS23755	COG2814	Major facilitator Superfamily
KM391_RS23760	COG0475	glutathione-regulated potassium exporter activity
KM391_RS23765	COG0490	domain, Protein
KM391_RS23770	COG0582	viral genome integration into host DNA
KM391_RS23780	COG1136	(ABC) transporter
KM391_RS23800	COG1242	4 iron, 4 sulfur cluster binding
KM391_RS23805	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM391_RS23810	COG1131	(ABC) transporter
KM391_RS23820	COG1794	racemase activity, acting on amino acids and derivatives
KM391_RS23840	COG2267	carboxylic ester hydrolase activity
KM391_RS23845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM391_RS23850	COG0671	phosphoesterase, PA-phosphatase related
KM391_RS23855	COG0438	transferase activity, transferring glycosyl groups
KM391_RS23865	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM391_RS23920	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM391_RS23925	COG5002	protein histidine kinase activity
KM391_RS23930	COG4191	Histidine kinase
KM391_RS23935	COG2267	carboxylic ester hydrolase activity
KM391_RS23940	COG1368	sulfuric ester hydrolase activity
KM391_RS23955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM391_RS23960	COG1116	anion transmembrane transporter activity
KM391_RS23965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM391_RS23990	COG0494	nUDIX hydrolase
KM391_RS24025	COG0288	reversible hydration of carbon dioxide
KM391_RS24030	COG1271	oxidase subunit
KM391_RS24035	COG1294	oxidase, subunit
KM391_RS24055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS24080	COG1842	Phage shock protein A
KM391_RS24110	COG5002	protein histidine kinase activity
KM391_RS24115	COG0745	RESPONSE REGULATOR receiver
KM391_RS24145	COG1597	lipid kinase activity
KM391_RS24180	COG0586	Pfam SNARE associated Golgi protein
KM391_RS24190	COG0577	efflux transmembrane transporter activity
KM391_RS24195	COG1136	(ABC) transporter
KM391_RS24200	COG2207	Transcriptional regulator
KM391_RS24200	COG3708	Transcriptional regulator
KM391_RS24205	COG0745	RESPONSE REGULATOR receiver
KM391_RS24210	COG2205	protein histidine kinase activity
KM391_RS24220	COG0577	efflux transmembrane transporter activity
KM391_RS24225	COG1136	(ABC) transporter
KM391_RS24245	COG2188	Transcriptional regulator
KM391_RS24265	COG3964	amidohydrolase
KM391_RS24295	COG4948	Mandelate Racemase Muconate Lactonizing
KM391_RS24305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM391_RS24310	COG0596	Alpha beta hydrolase
KM391_RS24315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KM391_RS24320	COG1169	isochorismate synthase
KM391_RS24325	COG1575	Belongs to the MenA family. Type 1 subfamily
KM391_RS24330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM391_RS24350	COG0058	SHG alpha-glucan phosphorylase activity
KM391_RS24355	COG0297	glycogen (starch) synthase activity
KM391_RS24360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KM391_RS24475	COG0544	peptidyl-prolyl cis-trans isomerase activity
KM391_RS24510	COG1285	pathogenesis
KM391_RS24515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM391_RS24525	COG0166	Belongs to the GPI family
KM391_RS24530	COG2155	Conserved Protein
KM391_RS24535	COG1098	S1 RNA binding domain
KM391_RS24540	COG0436	Aminotransferase
KM391_RS24545	COG1522	sequence-specific DNA binding
KM391_RS24550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM391_RS24555	COG2267	carboxylic ester hydrolase activity
KM391_RS24565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM391_RS24585	COG5018	Exonuclease
KM391_RS24590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM391_RS24610	COG2050	protein possibly involved in aromatic compounds catabolism
KM391_RS24620	COG1268	BioY protein
KM391_RS24630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM391_RS24635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM391_RS24650	COG3584	3D domain protein
KM391_RS24665	COG1252	NADH dehydrogenase
KM391_RS24680	COG3708	Transcriptional regulator
KM391_RS24695	COG1683	Conserved Protein
KM391_RS24715	COG0316	Belongs to the HesB IscA family
KM391_RS24730	COG1252	NADH dehydrogenase
KM391_RS24745	COG0390	transport system, permease component
KM391_RS24750	COG2824	Alkylphosphonate utilization operon protein PhnA
KM391_RS24790	COG4837	Protein of unknown function (DUF1462)
KM391_RS24795	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM391_RS24805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM391_RS24810	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM391_RS24820	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM391_RS24825	COG0647	UMP catabolic process
KM391_RS24835	COG2445	Protein of unknown function DUF86
KM391_RS24840	COG1494	fructose-1,6-bisphosphatase
KM391_RS24855	COG4470	Protein conserved in bacteria
KM391_RS24865	COG0789	Transcriptional regulator
KM391_RS24870	COG4377	Putative membrane peptidase family (DUF2324)
KM391_RS24895	COG0739	heme binding
KM391_RS24905	COG3377	Domain of unknown function (DUF1805)
KM391_RS24910	COG0737	Belongs to the 5'-nucleotidase family
KM391_RS24915	COG1695	Transcriptional regulator
KM391_RS24925	COG0719	Fe-S assembly protein
KM391_RS24930	COG0822	iron-sulfur transferase activity
KM391_RS24935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM391_RS24940	COG0719	Fe-S assembly protein
KM391_RS24945	COG0396	ATPase activity
KM391_RS24950	COG1464	Belongs to the NlpA lipoprotein family
KM391_RS24955	COG1464	Belongs to the NlpA lipoprotein family
KM391_RS24960	COG2011	ABC-type metal ion transport system permease component
KM391_RS24965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM391_RS24975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM391_RS24980	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM391_RS24990	COG1393	Belongs to the ArsC family
KM391_RS25035	COG0039	L-malate dehydrogenase activity
KM391_RS25060	COG1309	transcriptional regulator
KM391_RS25065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM391_RS25070	COG1960	acyl-CoA dehydrogenase activity
KM391_RS25075	COG0183	Belongs to the thiolase family
KM391_RS25080	COG1024	Enoyl-CoA hydratase
KM391_RS25080	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM391_RS25090	COG1686	Belongs to the peptidase S11 family
KM391_RS25105	COG0011	TIGRFAM Protein of
KM391_RS25110	COG0840	transmembrane signaling receptor activity
KM391_RS25130	COG2814	Major facilitator Superfamily
KM391_RS25135	COG0531	amino acid
KM391_RS25145	COG0706	membrane insertase activity
KM391_RS25155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM391_RS25190	COG0586	Pfam SNARE associated Golgi protein
KM391_RS25200	COG1376	ErfK ybiS ycfS ynhG family protein
KM391_RS25205	COG0745	RESPONSE REGULATOR receiver
KM391_RS25210	COG5002	protein histidine kinase activity
KM391_RS25235	COG2151	metal-sulfur cluster biosynthetic enzyme
KM391_RS25240	COG3227	Zinc metalloprotease (Elastase)
KM391_RS25245	COG1741	Belongs to the pirin family
KM391_RS25260	COG0475	glutathione-regulated potassium exporter activity
KM391_RS25265	COG0490	domain, Protein
KM391_RS25270	COG1115	amino acid carrier protein
KM391_RS25275	COG0783	Belongs to the Dps family
KM391_RS25290	COG1611	Belongs to the LOG family
KM391_RS25310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS25320	COG1115	amino acid carrier protein
KM391_RS25325	COG1115	amino acid carrier protein
KM391_RS25330	COG2910	NAD(P)H-binding
KM391_RS25345	COG0656	L-ascorbic acid biosynthetic process
KM391_RS25350	COG2814	Major facilitator Superfamily
KM391_RS25355	COG1733	regulation of RNA biosynthetic process
KM391_RS25365	COG1252	NADH dehydrogenase
KM391_RS25370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KM391_RS25375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KM391_RS25385	COG0840	transmembrane signaling receptor activity
KM391_RS25385	COG3290	protein histidine kinase activity
KM391_RS25395	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM391_RS25400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM391_RS25415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM391_RS25470	COG0557	exoribonuclease II activity
KM391_RS25475	COG1647	Serine aminopeptidase, S33
KM391_RS25480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM391_RS25485	COG1346	cytolysis
KM391_RS25580	COG4695	Portal protein
KM391_RS25605	COG4974	Belongs to the 'phage' integrase family
KM391_RS25615	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KM391_RS25620	COG0149	triose-phosphate isomerase activity
KM391_RS25630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM391_RS25645	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM391_RS25670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM391_RS25685	COG2323	membrane
KM391_RS25690	COG0740	serine-type endopeptidase activity
KM391_RS25695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM391_RS25705	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM391_RS25715	COG1051	belongs to the nudix hydrolase family
KM391_RS25725	COG0492	ferredoxin-NADP+ reductase activity
KM391_RS25730	COG0457	Tetratricopeptide repeat
KM391_RS25735	COG0110	maltose O-acetyltransferase activity
KM391_RS25755	COG1950	PFAM Membrane protein of
KM391_RS25765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM391_RS25770	COG0556	nucleotide-excision repair
KM391_RS25790	COG0789	Transcriptional regulator
KM391_RS25815	COG2855	membrane
KM391_RS25820	COG0583	DNA-binding transcription factor activity
KM391_RS25830	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM391_RS25835	COG0488	(ABC) transporter
KM391_RS25845	COG1132	(ABC) transporter
KM391_RS25850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM391_RS25855	COG0793	Belongs to the peptidase S41A family
KM391_RS25855	COG3409	Peptidoglycan-binding domain 1 protein
KM391_RS25860	COG2177	Part of the ABC transporter FtsEX involved in
KM391_RS25865	COG2884	Cell division ATP-binding protein ftsE
KM391_RS25880	COG0653	protein targeting
KM391_RS25885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM391_RS25890	COG1278	Cold shock
KM391_RS25895	COG1040	competence protein
KM391_RS25900	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM391_RS25905	COG1388	LysM domain
KM391_RS25905	COG0791	NLP P60 protein
KM391_RS25910	COG1733	regulation of RNA biosynthetic process
KM391_RS25915	COG1307	EDD domain protein, DegV family
KM391_RS25920	COG1739	Uncharacterized protein family UPF0029
KM391_RS25925	COG1316	TRANSCRIPTIONal
KM391_RS25930	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM391_RS25935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM391_RS25940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM391_RS25950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM391_RS25950	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KM391_RS25965	COG3394	polysaccharide catabolic process
KM391_RS25970	COG1486	melibiose metabolic process
KM391_RS25975	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM391_RS25980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM391_RS25990	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM391_RS25995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KM391_RS26000	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM391_RS26010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM391_RS26015	COG1301	dicarboxylic acid transport
KM391_RS26025	COG0346	lactoylglutathione lyase activity
KM391_RS26030	COG1511	domain protein
KM391_RS26035	COG0583	DNA-binding transcription factor activity
KM391_RS26040	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM391_RS26055	COG1271	oxidase subunit
KM391_RS26060	COG1294	oxidase, subunit
KM391_RS26065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM391_RS26075	COG1620	l-lactate permease
KM391_RS26085	COG2389	metal-binding protein
KM391_RS26095	COG1368	sulfuric ester hydrolase activity
KM391_RS26110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM391_RS26125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM391_RS26130	COG1388	LysM domain
KM391_RS26130	COG3584	3D domain protein
KM391_RS26155	COG4715	Zinc finger, swim domain protein
KM391_RS26160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM391_RS26200	COG0577	efflux transmembrane transporter activity
KM391_RS26205	COG1136	(ABC) transporter
KM391_RS26240	COG5002	protein histidine kinase activity
KM391_RS26245	COG0745	RESPONSE REGULATOR receiver
KM391_RS26250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM391_RS26270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM391_RS26275	COG1134	teichoic acid transport
KM391_RS26280	COG1682	transport, permease protein
KM391_RS26285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KM391_RS26330	COG1609	Transcriptional regulator
KM391_RS26345	COG0739	heme binding
KM391_RS26365	COG2385	sporulation resulting in formation of a cellular spore
KM391_RS26380	COG4836	Membrane
KM391_RS26385	COG1007	ATP synthesis coupled electron transport
KM391_RS26390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM391_RS26395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM391_RS26405	COG0839	Belongs to the complex I subunit 6 family
KM391_RS26420	COG0649	NAD binding
KM391_RS26425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KM391_RS26440	COG5001	Diguanylate cyclase
KM391_RS26440	COG3300	MHYT domain
KM391_RS26490	COG0356	it plays a direct role in the translocation of protons across the membrane
KM391_RS26525	COG0698	ribose 5-phosphate isomerase
KM391_RS26535	COG2190	(PTS) system
KM391_RS26540	COG2259	Doxx family
KM391_RS26545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM391_RS26560	COG0009	L-threonylcarbamoyladenylate synthase
KM391_RS26575	COG2890	protein-(glutamine-N5) methyltransferase activity
KM391_RS26595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM391_RS26600	COG1494	fructose-1,6-bisphosphatase
KM391_RS26620	COG4821	SIS domain
KM391_RS26630	COG3343	RNA polymerase activity
KM391_RS26640	COG1960	acyl-CoA dehydrogenase activity
KM391_RS26645	COG1960	acyl-CoA dehydrogenase activity
KM391_RS26650	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM391_RS26655	COG0183	Belongs to the thiolase family
KM391_RS26660	COG2181	nitrate reductase activity
KM391_RS26660	COG0247	lactate metabolic process
KM391_RS26665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM391_RS26675	COG5001	Diguanylate cyclase
KM391_RS26675	COG3300	MHYT domain
KM391_RS26695	COG2197	response regulator
KM391_RS26700	COG4585	Histidine kinase
KM391_RS26705	COG0842	Transport permease protein
KM391_RS26710	COG1131	(ABC) transporter
KM391_RS26715	COG0024	Methionine aminopeptidase
KM391_RS26725	COG2234	aminopeptidase activity
KM391_RS26745	COG1595	DNA-templated transcription, initiation
KM391_RS26750	COG0018	arginyl-trna synthetase
KM391_RS26755	COG4506	Protein conserved in bacteria
KM391_RS26760	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM391_RS26775	COG0010	Belongs to the arginase family
KM391_RS26785	COG2814	Major facilitator Superfamily
KM391_RS26790	COG0789	Transcriptional regulator
KM391_RS26795	COG0584	glycerophosphoryl diester phosphodiesterase
KM391_RS26800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM391_RS26810	COG1994	Peptidase M50
KM391_RS26820	COG1078	dGTPase activity
KM391_RS26825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM391_RS26830	COG1120	ATPase activity
KM391_RS26835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM391_RS26860	COG0095	Lipoate-protein ligase
KM391_RS26865	COG0280	phosphate acetyltransferase
KM391_RS26880	COG3773	Cell wall hydrolase
KM391_RS26890	COG2363	Small membrane protein
KM391_RS26905	COG2233	PERMEase
KM391_RS26910	COG0561	phosphatase activity
KM391_RS26915	COG2814	Major facilitator Superfamily
KM391_RS26925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM391_RS26930	COG1131	(ABC) transporter
KM391_RS26935	COG2755	lipolytic protein G-D-S-L family
KM391_RS26940	COG1609	Transcriptional regulator
KM391_RS26950	COG0460	homoserine dehydrogenase
KM391_RS26960	COG2873	o-acetylhomoserine
KM391_RS26970	COG1011	Hydrolase
KM391_RS26975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM391_RS26985	COG2197	response regulator
KM391_RS26995	COG0351	phosphomethylpyrimidine kinase
KM391_RS27000	COG3706	GGDEF domain
KM391_RS27005	COG2879	small protein
KM391_RS27010	COG1966	Carbon starvation protein
KM391_RS27015	COG3279	Response regulator of the LytR AlgR family
KM391_RS27020	COG0477	Major facilitator Superfamily
KM391_RS27045	COG0840	transmembrane signaling receptor activity
KM391_RS27055	COG1607	acyl-coa hydrolase
KM391_RS27070	COG0488	(ABC) transporter
KM391_RS27090	COG0463	Glycosyl transferase, family 2
KM391_RS27095	COG1309	transcriptional regulator
KM391_RS27100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM391_RS27105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM391_RS27105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KM391_RS27110	COG0628	permease
KM391_RS27125	COG3279	Response regulator of the LytR AlgR family
KM391_RS27130	COG3275	phosphorelay sensor kinase activity
KM391_RS27135	COG2814	Major facilitator Superfamily
KM391_RS27140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM391_RS27145	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM391_RS27150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM391_RS27170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM391_RS27175	COG1272	protein, Hemolysin III
KM391_RS27195	COG0516	GMP reductase activity
KM391_RS27200	COG1164	Oligoendopeptidase f
KM391_RS27220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM391_RS27225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM391_RS27230	COG4853	Protein conserved in bacteria
KM391_RS27235	COG4863	YycH protein
KM391_RS27240	COG5002	protein histidine kinase activity
KM391_RS27245	COG0745	RESPONSE REGULATOR receiver
KM391_RS27275	COG0305	Participates in initiation and elongation during chromosome replication
KM391_RS27285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM391_RS27290	COG4241	membrane
KM391_RS27300	COG0629	single-stranded DNA binding
KM391_RS27310	COG0012	GTP binding
KM391_RS27315	COG4481	Protein conserved in bacteria
KM391_RS27320	COG0668	transmembrane transport
KM391_RS27330	COG1475	DNA binding
KM391_RS27335	COG1192	Involved in chromosome partitioning
KM391_RS27360	COG1847	R3H domain protein
KM391_RS27365	COG0706	membrane insertase activity
KM391_RS27375	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KM391_RS27430	COG3344	reverse transcriptase
KM391_RS27510	COG3344	reverse transcriptase
KM391_RS27715	COG4962	Type ii secretion system protein e
KM391_RS27850	COG2311	Membrane
KM391_RS27870	COG4196	transglutaminase domain protein
KM391_RS27875	COG0671	phosphoesterase, PA-phosphatase related
KM391_RS27895	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM391_RS27900	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM391_RS28070	COG2002	toxin-antitoxin pair type II binding
KM391_RS28080	COG4974	Belongs to the 'phage' integrase family
KM391_RS28140	COG3443	Belongs to the bacterial solute-binding protein 9 family
KM391_RS28150	COG4974	Belongs to the 'phage' integrase family
KM391_RS28175	COG0457	Tetratricopeptide repeat
KM391_RS28380	COG0791	NLP P60 protein
KM391_RS28380	COG0741	lytic transglycosylase activity
KM391_RS28500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM391_RS28510	COG4166	transmembrane transport
KM391_RS28555	COG1280	lysine exporter protein (LysE YggA)
KM391_RS28590	COG0681	Belongs to the peptidase S26 family
KM391_RS28665	COG1309	transcriptional regulator
KM391_RS28670	COG1683	Conserved Protein
KM391_RS28715	COG1192	Involved in chromosome partitioning