locus-tag	class	description
BF39_RS00020	COG5634	Uncharacterized conserved protein (DUF2278)
BF39_RS00270	COG3835	regulator
BF39_RS00285	COG2205	protein histidine kinase activity
BF39_RS00455	COG2318	DinB family
BF39_RS00550	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_RS00730	COG0247	lactate metabolic process
BF39_RS00975	COG1131	(ABC) transporter
BF39_RS01210	COG0019	diaminopimelate decarboxylase activity
BF39_RS01215	COG0019	diaminopimelate decarboxylase activity
BF39_RS01355	COG1620	l-lactate permease
BF39_RS01360	COG5634	Uncharacterized conserved protein (DUF2278)
BF39_RS01410	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_RS01420	COG1476	TRANSCRIPTIONal
BF39_RS01480	COG2226	methyltransferase
BF39_RS01490	COG1686	Belongs to the peptidase S11 family
BF39_RS01495	COG0681	Belongs to the peptidase S26 family
BF39_RS01530	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS01535	COG3842	ATPase activity
BF39_RS01540	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF39_RS01545	COG1177	transmembrane transport
BF39_RS01550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF39_RS01560	COG2409	Drug exporters of the RND superfamily
BF39_RS01570	COG0564	pseudouridine synthase activity
BF39_RS01580	COG2340	Cysteine-rich secretory protein family
BF39_RS01585	COG0247	lactate metabolic process
BF39_RS01590	COG0277	FAD linked oxidase domain protein
BF39_RS01595	COG3835	regulator
BF39_RS01605	COG0745	RESPONSE REGULATOR receiver
BF39_RS01610	COG5002	protein histidine kinase activity
BF39_RS01615	COG2186	Transcriptional regulator
BF39_RS01635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF39_RS01645	COG2116	formate transmembrane transporter activity
BF39_RS01650	COG0861	Integral membrane protein TerC family
BF39_RS01665	COG2030	dehydratase
BF39_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS01690	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF39_RS01695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_RS01700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF39_RS01715	COG1840	ABC-type Fe3 transport system, periplasmic component
BF39_RS01745	COG1349	DNA-binding transcription factor activity
BF39_RS01770	COG2861	carbohydrate metabolic process
BF39_RS01780	COG3852	Histidine kinase
BF39_RS01785	COG1846	Transcriptional regulator
BF39_RS01795	COG2318	DinB family
BF39_RS01805	COG5002	protein histidine kinase activity
BF39_RS01815	COG0720	synthase
BF39_RS01830	COG4873	Protein conserved in bacteria
BF39_RS01865	COG1780	Probably involved in ribonucleotide reductase function
BF39_RS01880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF39_RS01885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF39_RS01890	COG1725	Transcriptional regulator
BF39_RS01895	COG1131	(ABC) transporter
BF39_RS01905	COG1131	(ABC) transporter
BF39_RS01910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF39_RS01925	COG1522	sequence-specific DNA binding
BF39_RS01935	COG1335	isochorismatase
BF39_RS01945	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF39_RS01950	COG2070	2-Nitropropane dioxygenase
BF39_RS01955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF39_RS01965	COG1696	Membrane protein involved in D-alanine export
BF39_RS01990	COG0716	FMN binding
BF39_RS02005	COG3173	Aminoglycoside phosphotransferase
BF39_RS02025	COG0534	Mate efflux family protein
BF39_RS02030	COG1968	undecaprenyl-diphosphatase activity
BF39_RS02045	COG1846	Transcriptional regulator
BF39_RS02055	COG1301	dicarboxylic acid transport
BF39_RS02060	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF39_RS02065	COG4709	membrane
BF39_RS02070	COG3874	Sporulation protein YtfJ
BF39_RS02100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_RS02105	COG0028	Belongs to the TPP enzyme family
BF39_RS02110	COG0440	acetolactate synthase activity
BF39_RS02115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF39_RS02125	COG0473	3-isopropylmalate dehydrogenase activity
BF39_RS02150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF39_RS02185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF39_RS02200	COG1183	phosphatidylcholine synthase activity
BF39_RS02205	COG1368	sulfuric ester hydrolase activity
BF39_RS02215	COG0019	diaminopimelate decarboxylase activity
BF39_RS02235	COG0529	Catalyzes the synthesis of activated sulfate
BF39_RS02240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF39_RS02260	COG1648	precorrin-2 dehydrogenase activity
BF39_RS02270	COG0733	neurotransmitter:sodium symporter activity
BF39_RS02290	COG1757	Na H antiporter
BF39_RS02305	COG4758	membrane
BF39_RS02310	COG4585	Histidine kinase
BF39_RS02315	COG2197	response regulator
BF39_RS02325	COG1114	Component of the transport system for branched-chain amino acids
BF39_RS02335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF39_RS02360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BF39_RS02360	COG1017	nitric oxide dioxygenase activity
BF39_RS02380	COG0730	response to heat
BF39_RS02385	COG0306	phosphate transporter
BF39_RS02390	COG1392	Phosphate transport regulator
BF39_RS02395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_RS02410	COG3852	Histidine kinase
BF39_RS02415	COG1801	Protein of unknown function DUF72
BF39_RS02425	COG0582	viral genome integration into host DNA
BF39_RS02430	COG5002	protein histidine kinase activity
BF39_RS02450	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF39_RS02450	COG0392	lysyltransferase activity
BF39_RS02465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF39_RS02470	COG1686	Belongs to the peptidase S11 family
BF39_RS02475	COG2715	membrane protein required for spore maturation
BF39_RS02480	COG0700	Nucleoside recognition
BF39_RS02485	COG1187	pseudouridine synthase activity
BF39_RS02495	COG1333	cytochrome c biogenesis protein
BF39_RS02500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF39_RS02505	COG0745	RESPONSE REGULATOR receiver
BF39_RS02510	COG5002	protein histidine kinase activity
BF39_RS02515	COG2096	Adenosyltransferase
BF39_RS02530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF39_RS02535	COG1141	Ferredoxin
BF39_RS02545	COG0514	ATP-dependent DNA helicase (RecQ)
BF39_RS02550	COG1266	CAAX protease self-immunity
BF39_RS02570	COG4862	establishment of competence for transformation
BF39_RS02575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF39_RS02595	COG0492	ferredoxin-NADP+ reductase activity
BF39_RS02600	COG0252	asparaginase activity
BF39_RS02670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF39_RS02685	COG0142	geranyltranstransferase activity
BF39_RS02695	COG0142	geranyltranstransferase activity
BF39_RS02715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF39_RS02720	COG0457	Tetratricopeptide repeat
BF39_RS02740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF39_RS02750	COG4347	Protein of unknown function (DUF1405)
BF39_RS02765	COG2738	Putative neutral zinc metallopeptidase
BF39_RS02775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS02780	COG1694	Mazg nucleotide pyrophosphohydrolase
BF39_RS02795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF39_RS02800	COG0438	transferase activity, transferring glycosyl groups
BF39_RS02840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF39_RS02840	COG1199	ATP-dependent helicase activity
BF39_RS02860	COG3935	DnaD domain protein
BF39_RS02865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF39_RS02875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_RS02875	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF39_RS02925	COG0116	Belongs to the methyltransferase superfamily
BF39_RS02935	COG1199	ATP-dependent helicase activity
BF39_RS02940	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF39_RS02950	COG3173	Aminoglycoside phosphotransferase
BF39_RS02955	COG0024	Methionine aminopeptidase
BF39_RS02965	COG2233	PERMEase
BF39_RS02970	COG2311	Membrane
BF39_RS02975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF39_RS02985	COG0456	acetyltransferase
BF39_RS03010	COG0754	glutathionylspermidine amidase activity
BF39_RS03025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF39_RS03050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF39_RS03065	COG1215	transferase activity, transferring glycosyl groups
BF39_RS03070	COG0438	transferase activity, transferring glycosyl groups
BF39_RS03085	COG0454	-acetyltransferase
BF39_RS03105	COG0328	RNA-DNA hybrid ribonuclease activity
BF39_RS03145	COG1280	lysine exporter protein (LysE YggA)
BF39_RS03160	COG3162	membrane
BF39_RS03165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_RS03170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF39_RS03180	COG0475	glutathione-regulated potassium exporter activity
BF39_RS03185	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF39_RS03190	COG4978	Transcriptional regulator
BF39_RS03190	COG0789	Transcriptional regulator
BF39_RS03200	COG2323	membrane
BF39_RS03205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF39_RS03260	COG1923	regulation of RNA biosynthetic process
BF39_RS03275	COG1360	Flagellar Motor Protein
BF39_RS03280	COG2201	protein-glutamate methylesterase activity
BF39_RS03290	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_RS03290	COG1776	CheC inhibitor of MCP methylation
BF39_RS03305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF39_RS03335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF39_RS03360	COG1815	bacterial-type flagellum-dependent cell motility
BF39_RS03365	COG1558	bacterial-type flagellum-dependent cell motility
BF39_RS03375	COG1766	The M ring may be actively involved in energy transduction
BF39_RS03385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_RS03395	COG1157	protein secretion by the type III secretion system
BF39_RS03435	COG0835	chemotaxis
BF39_RS03435	COG0784	Response regulator, receiver
BF39_RS03445	COG0463	Glycosyl transferase, family 2
BF39_RS03475	COG0457	Tetratricopeptide repeat
BF39_RS03475	COG0463	Glycosyl transferase, family 2
BF39_RS03500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF39_RS03505	COG0741	lytic transglycosylase activity
BF39_RS03520	COG1776	CheC inhibitor of MCP methylation
BF39_RS03520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF39_RS03530	COG1338	Plays a role in the flagellum-specific transport system
BF39_RS03535	COG1987	bacterial-type flagellum assembly
BF39_RS03545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF39_RS03550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF39_RS03555	COG1419	protein localization to endoplasmic reticulum
BF39_RS03560	COG4786	Flagellar basal body rod
BF39_RS03565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF39_RS03590	COG1309	transcriptional regulator
BF39_RS03610	COG2329	Antibiotic biosynthesis monooxygenase
BF39_RS03635	COG0583	DNA-binding transcription factor activity
BF39_RS03640	COG3842	ATPase activity
BF39_RS03645	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF39_RS03655	COG1234	tRNA 3'-trailer cleavage
BF39_RS03680	COG1686	Belongs to the peptidase S11 family
BF39_RS03690	COG0406	alpha-ribazole phosphatase activity
BF39_RS03720	COG0367	asparagine synthase
BF39_RS03750	COG1802	Transcriptional regulator
BF39_RS03755	COG0697	spore germination
BF39_RS03760	COG0523	cobalamin synthesis protein
BF39_RS03765	COG0701	Predicted permease
BF39_RS03775	COG0438	transferase activity, transferring glycosyl groups
BF39_RS03775	COG1216	Glycosyl transferase, family 2
BF39_RS03780	COG1757	Na H antiporter
BF39_RS03785	COG0114	fumarate hydratase activity
BF39_RS03815	COG3340	Belongs to the peptidase S51 family
BF39_RS03835	COG0785	Cytochrome C biogenesis protein
BF39_RS03870	COG2733	membrane
BF39_RS03905	COG1131	(ABC) transporter
BF39_RS03920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_RS03925	COG0528	UMP kinase activity
BF39_RS03935	COG1027	Aspartate ammonia-lyase
BF39_RS03940	COG0281	malic enzyme
BF39_RS03945	COG4191	Histidine kinase
BF39_RS03950	COG0784	Response regulator, receiver
BF39_RS03955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF39_RS04015	COG1051	belongs to the nudix hydrolase family
BF39_RS04020	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_RS04030	COG2814	Major facilitator Superfamily
BF39_RS04045	COG1966	Carbon starvation protein
BF39_RS04070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF39_RS04080	COG4166	transmembrane transport
BF39_RS04085	COG2223	nitrite transmembrane transporter activity
BF39_RS04090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF39_RS04105	COG2244	polysaccharide biosynthetic process
BF39_RS04110	COG0733	neurotransmitter:sodium symporter activity
BF39_RS04120	COG5566	PFAM Mor transcription activator
BF39_RS04125	COG2323	membrane
BF39_RS04140	COG2084	Dehydrogenase
BF39_RS04155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF39_RS04165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_RS04170	COG0028	Belongs to the TPP enzyme family
BF39_RS04175	COG0440	acetolactate synthase activity
BF39_RS04180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF39_RS04190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF39_RS04215	COG2814	Major facilitator Superfamily
BF39_RS04220	COG3384	dioxygenase
BF39_RS04230	COG3279	Response regulator of the LytR AlgR family
BF39_RS04235	COG0427	acetyl-CoA hydrolase
BF39_RS04255	COG1073	alpha beta
BF39_RS04260	COG4166	transmembrane transport
BF39_RS04285	COG0535	radical SAM domain protein
BF39_RS04290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS04310	COG1914	H( )-stimulated, divalent metal cation uptake system
BF39_RS04325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF39_RS04360	COG2390	Transcriptional regulator
BF39_RS04370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS04375	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF39_RS04390	COG4224	UPF0291 protein
BF39_RS04410	COG0006	proline dipeptidase activity
BF39_RS04430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF39_RS04445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF39_RS04460	COG2372	response to copper ion
BF39_RS04460	COG1276	copper resistance
BF39_RS04465	COG4549	nuclear export factor GLE1
BF39_RS04475	COG0697	spore germination
BF39_RS04480	COG0583	DNA-binding transcription factor activity
BF39_RS04485	COG1959	2 iron, 2 sulfur cluster binding
BF39_RS04490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF39_RS04495	COG0778	Nitroreductase
BF39_RS04510	COG0628	permease
BF39_RS04520	COG1231	oxidoreductase activity
BF39_RS04525	COG0523	cobalamin synthesis protein
BF39_RS04540	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_RS04545	COG2030	dehydratase
BF39_RS04550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_RS04560	COG0411	ABC transporter
BF39_RS04580	COG0583	DNA-binding transcription factor activity
BF39_RS04600	COG1846	Transcriptional regulator
BF39_RS04610	COG1271	oxidase subunit
BF39_RS04615	COG1294	oxidase, subunit
BF39_RS04620	COG4988	ABC transporter
BF39_RS04625	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF39_RS04645	COG1686	Belongs to the peptidase S11 family
BF39_RS04660	COG1388	LysM domain
BF39_RS04660	COG0791	NLP P60 protein
BF39_RS04670	COG1132	(ABC) transporter
BF39_RS04675	COG1132	(ABC) transporter
BF39_RS04680	COG0745	RESPONSE REGULATOR receiver
BF39_RS04685	COG5002	protein histidine kinase activity
BF39_RS04695	COG0300	oxidoreductase activity
BF39_RS04730	COG0460	homoserine dehydrogenase
BF39_RS04755	COG1316	TRANSCRIPTIONal
BF39_RS04765	COG0745	RESPONSE REGULATOR receiver
BF39_RS04770	COG5002	protein histidine kinase activity
BF39_RS04785	COG1285	pathogenesis
BF39_RS04790	COG1247	-acetyltransferase
BF39_RS04810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF39_RS04820	COG1082	Xylose isomerase domain protein TIM barrel
BF39_RS04835	COG1279	arginine transmembrane transporter activity
BF39_RS04845	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF39_RS04885	COG2002	toxin-antitoxin pair type II binding
BF39_RS04890	COG1404	Belongs to the peptidase S8 family
BF39_RS04895	COG0640	Transcriptional regulator
BF39_RS04900	COG0667	Aldo Keto reductase
BF39_RS04905	COG2814	Major facilitator Superfamily
BF39_RS04930	COG0840	transmembrane signaling receptor activity
BF39_RS04950	COG3949	Membrane
BF39_RS04955	COG0783	Belongs to the Dps family
BF39_RS04970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF39_RS04980	COG1231	oxidoreductase activity
BF39_RS04990	COG4989	oxidoreductase activity
BF39_RS04995	COG0523	cobalamin synthesis protein
BF39_RS05000	COG0456	acetyltransferase
BF39_RS05065	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF39_RS05065	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF39_RS05075	COG0702	epimerase
BF39_RS05085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF39_RS05095	COG4166	transmembrane transport
BF39_RS05110	COG0406	alpha-ribazole phosphatase activity
BF39_RS05120	COG5337	Spore coat protein CotH
BF39_RS05125	COG1051	belongs to the nudix hydrolase family
BF39_RS05130	COG0586	Pfam SNARE associated Golgi protein
BF39_RS05135	COG2244	polysaccharide biosynthetic process
BF39_RS05145	COG0701	Predicted permease
BF39_RS05150	COG3689	TIGRFAM TIGR03943 family protein
BF39_RS05155	COG1607	acyl-coa hydrolase
BF39_RS05160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_RS05175	COG0702	epimerase
BF39_RS05180	COG2839	Protein conserved in bacteria
BF39_RS05185	COG1253	flavin adenine dinucleotide binding
BF39_RS05200	COG1114	Component of the transport system for branched-chain amino acids
BF39_RS05205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_RS05225	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_RS05235	COG1876	peptidase activity
BF39_RS05245	COG0154	amidase activity
BF39_RS05250	COG2211	Major facilitator Superfamily
BF39_RS05270	COG0561	phosphatase activity
BF39_RS05280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF39_RS05285	COG4106	trans-aconitate 2-methyltransferase activity
BF39_RS05300	COG1819	glycosyl
BF39_RS05305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS05310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS05335	COG0456	acetyltransferase
BF39_RS05385	COG3874	Sporulation protein YtfJ
BF39_RS05410	COG2226	methyltransferase
BF39_RS05430	COG1082	Xylose isomerase domain protein TIM barrel
BF39_RS05435	COG0346	lactoylglutathione lyase activity
BF39_RS05445	COG0604	alcohol dehydrogenase
BF39_RS05450	COG1595	DNA-templated transcription, initiation
BF39_RS05475	COG0386	Belongs to the glutathione peroxidase family
BF39_RS05480	COG1305	Transglutaminase-like
BF39_RS05485	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF39_RS05490	COG0714	Associated with various cellular activities
BF39_RS05505	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF39_RS05510	COG1140	nitrate reductase beta subunit
BF39_RS05515	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF39_RS05520	COG2181	nitrate reductase activity
BF39_RS05540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF39_RS05545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF39_RS05550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_RS05555	COG0303	'Molybdopterin
BF39_RS05560	COG0314	molybdopterin synthase activity
BF39_RS05570	COG2223	nitrite transmembrane transporter activity
BF39_RS05585	COG1648	precorrin-2 dehydrogenase activity
BF39_RS05595	COG1587	Uroporphyrinogen-III synthase
BF39_RS05595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF39_RS05600	COG2146	nitrite reductase [NAD(P)H] activity
BF39_RS05605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF39_RS05610	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF39_RS05645	COG2359	stage V sporulation protein S
BF39_RS05660	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_RS05675	COG1418	mRNA catabolic process
BF39_RS05680	COG0488	(ABC) transporter
BF39_RS05695	COG0629	single-stranded DNA binding
BF39_RS05710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF39_RS05715	COG1413	lyase activity
BF39_RS05730	COG2136	Putative SAM-dependent methyltransferase
BF39_RS05730	COG2521	methyltransferase
BF39_RS05735	COG0018	arginyl-trna synthetase
BF39_RS05760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF39_RS05775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF39_RS05780	COG0017	Asparaginyl-tRNA synthetase
BF39_RS05800	COG1674	ftsk spoiiie
BF39_RS05895	COG1929	Belongs to the glycerate kinase type-1 family
BF39_RS05900	COG0471	metal ion transport
BF39_RS05905	COG0745	RESPONSE REGULATOR receiver
BF39_RS05910	COG5002	protein histidine kinase activity
BF39_RS05910	COG3850	Histidine kinase
BF39_RS05925	COG0733	neurotransmitter:sodium symporter activity
BF39_RS05950	COG2610	gluconate transmembrane transporter activity
BF39_RS05955	COG1454	alcohol dehydrogenase
BF39_RS05960	COG1794	racemase activity, acting on amino acids and derivatives
BF39_RS05970	COG0456	acetyltransferase
BF39_RS05985	COG1131	(ABC) transporter
BF39_RS05990	COG4473	ABC transporter
BF39_RS06000	COG0546	phosphoglycolate phosphatase activity
BF39_RS06020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_RS06035	COG0768	penicillin binding
BF39_RS06040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF39_RS06045	COG0204	Acyl-transferase
BF39_RS06050	COG1272	protein, Hemolysin III
BF39_RS06060	COG0805	protein transport
BF39_RS06070	COG1307	EDD domain protein, DegV family
BF39_RS06075	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF39_RS06080	COG1999	signal sequence binding
BF39_RS06085	COG0071	Belongs to the small heat shock protein (HSP20) family
BF39_RS06090	COG0367	asparagine synthase
BF39_RS06110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS06115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_RS06150	COG0668	transmembrane transport
BF39_RS06155	COG2203	Gaf domain
BF39_RS06155	COG4585	Histidine kinase
BF39_RS06160	COG2197	response regulator
BF39_RS06170	COG1737	Transcriptional regulator
BF39_RS06175	COG1064	alcohol dehydrogenase
BF39_RS06205	COG1070	Carbohydrate kinase
BF39_RS06210	COG1070	Carbohydrate kinase
BF39_RS06240	COG0517	IMP dehydrogenase activity
BF39_RS06240	COG1125	glycine betaine transport
BF39_RS06245	COG1174	glycine betaine transport
BF39_RS06280	COG1253	flavin adenine dinucleotide binding
BF39_RS06285	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS06290	COG5506	Protein of unknown function (DUF1694)
BF39_RS06305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF39_RS06310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF39_RS06315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF39_RS06320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_RS06325	COG0456	acetyltransferase
BF39_RS06330	COG3829	transcription factor binding
BF39_RS06335	COG1509	lysine 2,3-aminomutase activity
BF39_RS06375	COG4326	sporulation control protein
BF39_RS06380	COG0671	phosphoesterase, PA-phosphatase related
BF39_RS06385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF39_RS06390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_RS06420	COG1787	Restriction endonuclease
BF39_RS06420	COG1715	Restriction endonuclease
BF39_RS06510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF39_RS06555	COG2814	Major facilitator Superfamily
BF39_RS06560	COG4841	protein insertion into membrane
BF39_RS06565	COG0372	Belongs to the citrate synthase family
BF39_RS06570	COG2079	MmgE PrpD family protein
BF39_RS06575	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF39_RS06580	COG1960	acyl-CoA dehydrogenase activity
BF39_RS06585	COG2084	Dehydrogenase
BF39_RS06595	COG1280	lysine exporter protein (LysE YggA)
BF39_RS06600	COG1024	Enoyl-CoA hydratase
BF39_RS06615	COG0420	3'-5' exonuclease activity
BF39_RS06620	COG0419	ATPase involved in DNA repair
BF39_RS06650	COG2223	nitrite transmembrane transporter activity
BF39_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS06660	COG1169	isochorismate synthase
BF39_RS06665	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF39_RS06670	COG3433	isochorismatase activity
BF39_RS06670	COG1535	isochorismatase
BF39_RS06675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF39_RS06680	COG3251	PFAM MbtH domain protein
BF39_RS06685	COG2814	Major facilitator Superfamily
BF39_RS06700	COG0776	regulation of translation
BF39_RS06710	COG2318	DinB family
BF39_RS06720	COG1115	amino acid carrier protein
BF39_RS06740	COG2329	Antibiotic biosynthesis monooxygenase
BF39_RS06745	COG1187	pseudouridine synthase activity
BF39_RS06750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF39_RS06765	COG0596	Alpha beta hydrolase
BF39_RS06770	COG2814	Major facilitator Superfamily
BF39_RS06790	COG2226	methyltransferase
BF39_RS06835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS06870	COG1247	-acetyltransferase
BF39_RS06900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF39_RS06910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS06920	COG1278	Cold shock
BF39_RS06935	COG0010	Belongs to the arginase family
BF39_RS06940	COG0561	phosphatase activity
BF39_RS06985	COG0583	DNA-binding transcription factor activity
BF39_RS06990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF39_RS07005	COG0583	DNA-binding transcription factor activity
BF39_RS07010	COG2258	MOSC domain
BF39_RS07025	COG1132	(ABC) transporter
BF39_RS07030	COG1132	(ABC) transporter
BF39_RS07050	COG1396	sequence-specific DNA binding
BF39_RS07075	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BF39_RS07080	COG1595	DNA-templated transcription, initiation
BF39_RS07105	COG1649	PFAM Uncharacterised BCR, COG1649
BF39_RS07130	COG2971	BadF BadG BcrA BcrD
BF39_RS07135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF39_RS07140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF39_RS07160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS07190	COG1309	transcriptional regulator
BF39_RS07205	COG1136	(ABC) transporter
BF39_RS07205	COG0577	efflux transmembrane transporter activity
BF39_RS07210	COG0500	methyltransferase
BF39_RS07210	COG3615	Tellurite resistance protein tehB
BF39_RS07220	COG2226	methyltransferase
BF39_RS07225	COG3961	Belongs to the TPP enzyme family
BF39_RS07230	COG1846	Transcriptional regulator
BF39_RS07270	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF39_RS07285	COG1595	DNA-templated transcription, initiation
BF39_RS07295	COG0768	penicillin binding
BF39_RS07305	COG2367	Beta-lactamase
BF39_RS07310	COG0671	phosphoesterase, PA-phosphatase related
BF39_RS07315	COG1609	Transcriptional regulator
BF39_RS07320	COG2814	Major facilitator Superfamily
BF39_RS07325	COG0673	inositol 2-dehydrogenase activity
BF39_RS07335	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS07350	COG0191	fructose-bisphosphate aldolase activity
BF39_RS07355	COG3718	enzyme involved in inositol metabolism
BF39_RS07385	COG0457	Tetratricopeptide repeat
BF39_RS07390	COG1476	TRANSCRIPTIONal
BF39_RS07405	COG1876	peptidase activity
BF39_RS07425	COG1309	transcriptional regulator
BF39_RS07430	COG0488	(ABC) transporter
BF39_RS07445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS07455	COG1252	NADH dehydrogenase
BF39_RS07460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_RS07475	COG1131	(ABC) transporter
BF39_RS07485	COG1309	transcriptional regulator
BF39_RS07500	COG1960	acyl-CoA dehydrogenase activity
BF39_RS07505	COG0439	Biotin carboxylase
BF39_RS07510	COG0511	ligase activity, forming carbon-carbon bonds
BF39_RS07515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF39_RS07520	COG1024	Enoyl-CoA hydratase
BF39_RS07525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF39_RS07530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF39_RS07540	COG1247	-acetyltransferase
BF39_RS07545	COG0572	uridine kinase
BF39_RS07555	COG2318	DinB family
BF39_RS07560	COG1686	Belongs to the peptidase S11 family
BF39_RS07585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF39_RS07625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF39_RS07625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF39_RS07650	COG2814	Major facilitator Superfamily
BF39_RS07670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF39_RS07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS07705	COG1063	alcohol dehydrogenase
BF39_RS07720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF39_RS07725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF39_RS07740	COG3773	Cell wall hydrolase
BF39_RS07750	COG0745	RESPONSE REGULATOR receiver
BF39_RS07765	COG0488	(ABC) transporter
BF39_RS07780	COG1136	(ABC) transporter
BF39_RS07805	COG0460	homoserine dehydrogenase
BF39_RS07810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS07820	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF39_RS07895	COG2124	cytochrome p450
BF39_RS07930	COG0561	phosphatase activity
BF39_RS07940	COG5002	protein histidine kinase activity
BF39_RS07945	COG0768	penicillin binding
BF39_RS07950	COG1819	glycosyl
BF39_RS07955	COG1794	racemase activity, acting on amino acids and derivatives
BF39_RS07965	COG1122	ATPase activity
BF39_RS07975	COG2205	protein histidine kinase activity
BF39_RS07985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_RS07990	COG0604	alcohol dehydrogenase
BF39_RS07995	COG0768	penicillin binding
BF39_RS08040	COG0693	protein deglycase activity
BF39_RS08070	COG2814	Major facilitator Superfamily
BF39_RS08105	COG0697	spore germination
BF39_RS08130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_RS08140	COG2223	nitrite transmembrane transporter activity
BF39_RS08155	COG2816	NAD+ diphosphatase activity
BF39_RS08160	COG0592	DNA-directed DNA polymerase activity
BF39_RS08165	COG1051	belongs to the nudix hydrolase family
BF39_RS08200	COG3878	Protein conserved in bacteria
BF39_RS08230	COG4667	esterase of the alpha-beta hydrolase superfamily
BF39_RS08255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF39_RS08270	COG0322	excinuclease ABC activity
BF39_RS08310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_RS08335	COG1011	Hydrolase
BF39_RS08355	COG0076	glutamate decarboxylase activity
BF39_RS08370	COG1523	belongs to the glycosyl hydrolase 13 family
BF39_RS08375	COG3227	Zinc metalloprotease (Elastase)
BF39_RS08395	COG0201	protein transport
BF39_RS08405	COG0697	spore germination
BF39_RS08410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS08440	COG4129	membrane
BF39_RS08445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS08460	COG2959	enzyme of heme biosynthesis
BF39_RS08480	COG3483	tryptophan 2,3-dioxygenase activity
BF39_RS08485	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BF39_RS08490	COG3844	kynureninase activity
BF39_RS08495	COG1309	transcriptional regulator
BF39_RS08525	COG3284	Transcriptional regulator
BF39_RS08545	COG1349	DNA-binding transcription factor activity
BF39_RS08565	COG1959	2 iron, 2 sulfur cluster binding
BF39_RS08580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF39_RS08585	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_RS08590	COG0022	dehydrogenase e1 component
BF39_RS08595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF39_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS08610	COG0456	acetyltransferase
BF39_RS08610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_RS08645	COG4176	ABC-type proline glycine betaine transport system permease component
BF39_RS08650	COG4175	Glycine betaine
BF39_RS08650	COG0517	IMP dehydrogenase activity
BF39_RS08675	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF39_RS08680	COG2153	protein acetylation
BF39_RS08685	COG3397	chitin binding
BF39_RS08700	COG2205	protein histidine kinase activity
BF39_RS08730	COG0658	competence protein
BF39_RS08730	COG2333	competence protein COMEC
BF39_RS08780	COG3973	AAA domain
BF39_RS08795	COG2105	PFAM AIG2 family protein
BF39_RS08800	COG0514	ATP-dependent DNA helicase (RecQ)
BF39_RS08830	COG4637	Psort location Cytoplasmic, score
BF39_RS08855	COG3397	chitin binding
BF39_RS08865	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF39_RS08870	COG1115	amino acid carrier protein
BF39_RS08875	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS08880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF39_RS08890	COG3938	Belongs to the proline racemase family
BF39_RS08895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_RS08935	COG0586	Pfam SNARE associated Golgi protein
BF39_RS08950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF39_RS08955	COG0519	Catalyzes the synthesis of GMP from XMP
BF39_RS08960	COG4166	transmembrane transport
BF39_RS08970	COG4948	Mandelate Racemase Muconate Lactonizing
BF39_RS09010	COG2936	dipeptidyl-peptidase activity
BF39_RS09015	COG5002	protein histidine kinase activity
BF39_RS09020	COG0745	RESPONSE REGULATOR receiver
BF39_RS09060	COG1307	EDD domain protein, DegV family
BF39_RS09080	COG2814	Major facilitator Superfamily
BF39_RS09090	COG1664	Polymer-forming cytoskeletal
BF39_RS09095	COG0789	Transcriptional regulator
BF39_RS09100	COG4533	DNA binding
BF39_RS09105	COG2814	Major facilitator Superfamily
BF39_RS09105	COG0477	Major facilitator Superfamily
BF39_RS09125	COG2261	transglycosylase associated protein
BF39_RS09140	COG2226	methyltransferase
BF39_RS09175	COG0436	Aminotransferase
BF39_RS09180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF39_RS09185	COG5146	pantothenate kinase activity
BF39_RS09205	COG1131	(ABC) transporter
BF39_RS09255	COG0628	permease
BF39_RS09270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF39_RS09275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_RS09280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF39_RS09285	COG1116	anion transmembrane transporter activity
BF39_RS09305	COG2816	NAD+ diphosphatase activity
BF39_RS09325	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF39_RS09350	COG0697	spore germination
BF39_RS09355	COG2318	DinB family
BF39_RS09375	COG4912	Dna alkylation repair
BF39_RS09395	COG0861	Integral membrane protein TerC family
BF39_RS09400	COG1368	sulfuric ester hydrolase activity
BF39_RS09405	COG0488	(ABC) transporter
BF39_RS09415	COG2409	Drug exporters of the RND superfamily
BF39_RS09415	COG1033	growth of symbiont in host cell
BF39_RS09420	COG1033	growth of symbiont in host cell
BF39_RS09420	COG2409	Drug exporters of the RND superfamily
BF39_RS09425	COG2409	Drug exporters of the RND superfamily
BF39_RS09425	COG1033	growth of symbiont in host cell
BF39_RS09430	COG1309	transcriptional regulator
BF39_RS09445	COG0287	Prephenate dehydrogenase
BF39_RS09450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF39_RS09455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF39_RS09460	COG1605	Chorismate mutase
BF39_RS09460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF39_RS09495	COG3584	3D domain protein
BF39_RS09495	COG1388	LysM domain
BF39_RS09505	COG1595	DNA-templated transcription, initiation
BF39_RS09530	COG1879	ABC-type sugar transport system periplasmic component
BF39_RS09540	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF39_RS09550	COG2390	Transcriptional regulator
BF39_RS09585	COG2329	Antibiotic biosynthesis monooxygenase
BF39_RS09605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS09615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF39_RS09620	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_RS09625	COG4187	Peptidase family M20/M25/M40
BF39_RS09630	COG1414	Transcriptional regulator
BF39_RS09635	COG0833	amino acid
BF39_RS09640	COG1690	Belongs to the RtcB family
BF39_RS09645	COG3239	Fatty acid desaturase
BF39_RS09650	COG1785	Belongs to the alkaline phosphatase family
BF39_RS09660	COG3655	Transcriptional regulator
BF39_RS09675	COG4377	Putative membrane peptidase family (DUF2324)
BF39_RS09685	COG3279	Response regulator of the LytR AlgR family
BF39_RS09695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS09700	COG0346	lactoylglutathione lyase activity
BF39_RS09720	COG0714	Associated with various cellular activities
BF39_RS09745	COG0463	Glycosyl transferase, family 2
BF39_RS09770	COG0463	Glycosyl transferase, family 2
BF39_RS09780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF39_RS09785	COG0753	catalase activity
BF39_RS09795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF39_RS09820	COG0714	Associated with various cellular activities
BF39_RS09830	COG0778	Nitroreductase
BF39_RS09835	COG1846	Transcriptional regulator
BF39_RS09870	COG1725	Transcriptional regulator
BF39_RS09880	COG0577	efflux transmembrane transporter activity
BF39_RS09880	COG1136	(ABC) transporter
BF39_RS09905	COG2207	Transcriptional regulator
BF39_RS09910	COG0456	acetyltransferase
BF39_RS09930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS09950	COG0642	Histidine kinase
BF39_RS09955	COG0745	RESPONSE REGULATOR receiver
BF39_RS09960	COG0596	Alpha beta hydrolase
BF39_RS09990	COG0730	response to heat
BF39_RS10000	COG0833	amino acid
BF39_RS10010	COG4335	DNA alkylation repair
BF39_RS10050	COG0768	penicillin binding
BF39_RS10060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF39_RS10095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF39_RS10100	COG1414	Transcriptional regulator
BF39_RS10115	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_RS10120	COG0640	Transcriptional regulator
BF39_RS10130	COG1960	acyl-CoA dehydrogenase activity
BF39_RS10150	COG3314	Sporulation integral membrane protein YlbJ
BF39_RS10165	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BF39_RS10180	COG0574	Belongs to the PEP-utilizing enzyme family
BF39_RS10180	COG3848	Pyruvate phosphate dikinase
BF39_RS10185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS10200	COG5577	PFAM Coat F domain
BF39_RS10205	COG3403	YqcI/YcgG family
BF39_RS10210	COG1280	lysine exporter protein (LysE YggA)
BF39_RS10245	COG1063	alcohol dehydrogenase
BF39_RS10260	COG1027	Aspartate ammonia-lyase
BF39_RS10265	COG0252	asparaginase activity
BF39_RS10270	COG1396	sequence-specific DNA binding
BF39_RS10280	COG0322	excinuclease ABC activity
BF39_RS10285	COG0531	amino acid
BF39_RS10290	COG1114	Component of the transport system for branched-chain amino acids
BF39_RS10295	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_RS10305	COG0281	malic enzyme
BF39_RS10325	COG0531	amino acid
BF39_RS10330	COG0697	spore germination
BF39_RS10335	COG0784	Response regulator, receiver
BF39_RS10345	COG2066	Belongs to the glutaminase family
BF39_RS10350	COG1115	amino acid carrier protein
BF39_RS10375	COG0737	Belongs to the 5'-nucleotidase family
BF39_RS10380	COG0753	catalase activity
BF39_RS10385	COG2267	carboxylic ester hydrolase activity
BF39_RS10390	COG1335	isochorismatase
BF39_RS10415	COG0583	DNA-binding transcription factor activity
BF39_RS10460	COG0415	Belongs to the DNA photolyase family
BF39_RS10465	COG0288	reversible hydration of carbon dioxide
BF39_RS10475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF39_RS10480	COG5609	conserved protein (DUF2294)
BF39_RS10490	COG1575	Belongs to the MenA family. Type 1 subfamily
BF39_RS10495	COG2267	carboxylic ester hydrolase activity
BF39_RS10500	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF39_RS10505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF39_RS10510	COG1121	(ABC) transporter
BF39_RS10540	COG0798	PFAM Bile acid sodium symporter
BF39_RS10545	COG0346	lactoylglutathione lyase activity
BF39_RS10550	COG0640	Transcriptional regulator
BF39_RS10565	COG0443	Heat shock 70 kDa protein
BF39_RS10580	COG1522	sequence-specific DNA binding
BF39_RS10595	COG0346	lactoylglutathione lyase activity
BF39_RS10620	COG2169	Transcriptional regulator
BF39_RS10665	COG2814	Major facilitator Superfamily
BF39_RS10690	COG0745	RESPONSE REGULATOR receiver
BF39_RS10695	COG5002	protein histidine kinase activity
BF39_RS10695	COG3850	Histidine kinase
BF39_RS10725	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF39_RS10750	COG1476	TRANSCRIPTIONal
BF39_RS10765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS10770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF39_RS10780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_RS10785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF39_RS10800	COG1136	(ABC) transporter
BF39_RS10805	COG0577	efflux transmembrane transporter activity
BF39_RS10825	COG5002	protein histidine kinase activity
BF39_RS10825	COG3850	Histidine kinase
BF39_RS10835	COG2364	Membrane
BF39_RS10840	COG1846	Transcriptional regulator
BF39_RS10850	COG2808	Putative FMN-binding domain
BF39_RS10855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS10860	COG2271	Major facilitator Superfamily
BF39_RS10865	COG1556	Lactate utilization protein
BF39_RS10870	COG1139	Iron-sulfur cluster binding protein
BF39_RS10880	COG0583	DNA-binding transcription factor activity
BF39_RS10890	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF39_RS10915	COG0738	Major facilitator superfamily
BF39_RS10920	COG0673	inositol 2-dehydrogenase activity
BF39_RS10925	COG0561	phosphatase activity
BF39_RS10935	COG1609	Transcriptional regulator
BF39_RS10940	COG0457	Tetratricopeptide repeat
BF39_RS10960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF39_RS10990	COG0534	Mate efflux family protein
BF39_RS11005	COG2814	Major facilitator Superfamily
BF39_RS11010	COG1309	transcriptional regulator
BF39_RS11025	COG0814	amino acid
BF39_RS11030	COG1760	l-serine dehydratase
BF39_RS11035	COG1760	l-serine dehydratase
BF39_RS11045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF39_RS11050	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BF39_RS11060	COG1335	isochorismatase
BF39_RS11065	COG1522	sequence-specific DNA binding
BF39_RS11070	COG0531	amino acid
BF39_RS11085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF39_RS11105	COG1595	DNA-templated transcription, initiation
BF39_RS11120	COG0662	Cupin 2, conserved barrel domain protein
BF39_RS11130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS11130	COG2207	Transcriptional regulator
BF39_RS11185	COG0477	Major facilitator Superfamily
BF39_RS11195	COG1846	Transcriptional regulator
BF39_RS11200	COG2814	Major facilitator Superfamily
BF39_RS11215	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF39_RS11220	COG1131	(ABC) transporter
BF39_RS11240	COG2076	Multidrug Resistance protein
BF39_RS11245	COG1309	transcriptional regulator
BF39_RS11260	COG2031	fatty acid transporter
BF39_RS11270	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_RS11300	COG1122	ATPase activity
BF39_RS11305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF39_RS11320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BF39_RS11325	COG1288	antiporter activity
BF39_RS11330	COG2356	endonuclease I
BF39_RS11345	COG3620	sequence-specific DNA binding
BF39_RS11350	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF39_RS11355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF39_RS11360	COG0124	histidyl-tRNA synthetase
BF39_RS11375	COG1733	regulation of RNA biosynthetic process
BF39_RS11380	COG0778	Nitroreductase
BF39_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS11410	COG1131	(ABC) transporter
BF39_RS11435	COG1011	Hydrolase
BF39_RS11445	COG2365	Tyrosine phosphatase family
BF39_RS11470	COG0346	lactoylglutathione lyase activity
BF39_RS11475	COG1940	carbohydrate kinase activity
BF39_RS11480	COG0738	Major facilitator superfamily
BF39_RS11485	COG0110	maltose O-acetyltransferase activity
BF39_RS11495	COG0577	efflux transmembrane transporter activity
BF39_RS11495	COG1136	(ABC) transporter
BF39_RS11505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF39_RS11510	COG0628	permease
BF39_RS11530	COG2226	methyltransferase
BF39_RS11540	COG0477	Major facilitator Superfamily
BF39_RS11570	COG1253	flavin adenine dinucleotide binding
BF39_RS11575	COG0789	Transcriptional regulator
BF39_RS11580	COG0697	spore germination
BF39_RS11585	COG1357	PFAM Pentapeptide repeats (8 copies)
BF39_RS11590	COG3813	Protein conserved in bacteria
BF39_RS11595	COG2706	6-phosphogluconolactonase activity
BF39_RS11600	COG1070	Carbohydrate kinase
BF39_RS11610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF39_RS11615	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF39_RS11625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF39_RS11630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF39_RS11635	COG0604	alcohol dehydrogenase
BF39_RS11640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF39_RS11650	COG0604	alcohol dehydrogenase
BF39_RS11650	COG3321	synthase
BF39_RS11660	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS11685	COG0656	L-ascorbic acid biosynthetic process
BF39_RS11690	COG2814	Major facilitator Superfamily
BF39_RS11705	COG0346	lactoylglutathione lyase activity
BF39_RS11710	COG0814	amino acid
BF39_RS11735	COG1393	Belongs to the ArsC family
BF39_RS11745	COG1733	regulation of RNA biosynthetic process
BF39_RS11750	COG2188	Transcriptional regulator
BF39_RS11760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF39_RS11765	COG1733	regulation of RNA biosynthetic process
BF39_RS11770	COG1733	regulation of RNA biosynthetic process
BF39_RS11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS11805	COG0384	phenazine biosynthesis protein PhzF
BF39_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS11825	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_RS11835	COG1733	regulation of RNA biosynthetic process
BF39_RS11870	COG1191	sigma factor activity
BF39_RS11885	COG1309	transcriptional regulator
BF39_RS11905	COG3152	Membrane
BF39_RS11930	COG1151	hydroxylamine reductase activity
BF39_RS11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS11945	COG3757	hydrolase, family 25
BF39_RS11945	COG3409	Peptidoglycan-binding domain 1 protein
BF39_RS11980	COG2072	flavoprotein involved in K transport
BF39_RS12015	COG0604	alcohol dehydrogenase
BF39_RS12020	COG1113	amino acid transport
BF39_RS12025	COG2814	Major facilitator Superfamily
BF39_RS12060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF39_RS12065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF39_RS12085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS12095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS12100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS12105	COG3739	integral membrane protein
BF39_RS12110	COG0384	phenazine biosynthesis protein PhzF
BF39_RS12140	COG0583	DNA-binding transcription factor activity
BF39_RS12160	COG1193	negative regulation of DNA recombination
BF39_RS12175	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF39_RS12180	COG1164	Oligoendopeptidase f
BF39_RS12185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_RS12215	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_RS12240	COG0640	Transcriptional regulator
BF39_RS12245	COG0604	alcohol dehydrogenase
BF39_RS12265	COG2808	Putative FMN-binding domain
BF39_RS12270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_RS12280	COG0385	Bile acid
BF39_RS12285	COG0277	FAD linked oxidase domain protein
BF39_RS12320	COG1216	Glycosyl transferase, family 2
BF39_RS12325	COG1024	Enoyl-CoA hydratase
BF39_RS12335	COG1285	pathogenesis
BF39_RS12345	COG2514	catechol 2,3-dioxygenase activity
BF39_RS12350	COG2720	vancomycin resistance protein
BF39_RS12390	COG0716	FMN binding
BF39_RS12420	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS12430	COG0165	Argininosuccinate lyase
BF39_RS12445	COG4145	pantothenate transmembrane transporter activity
BF39_RS12455	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS12470	COG1657	PFAM Prenyltransferase squalene oxidase
BF39_RS12475	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF39_RS12480	COG2962	Rard protein
BF39_RS12485	COG3326	Membrane
BF39_RS12500	COG0489	protein tyrosine kinase activity
BF39_RS12510	COG0314	molybdopterin synthase activity
BF39_RS12515	COG0303	'Molybdopterin
BF39_RS12520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_RS12525	COG2116	formate transmembrane transporter activity
BF39_RS12535	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF39_RS12540	COG5609	conserved protein (DUF2294)
BF39_RS12545	COG2427	Protein of unknown function (DUF1641)
BF39_RS12550	COG3383	formate dehydrogenase (NAD+) activity
BF39_RS12560	COG0697	spore germination
BF39_RS12600	COG2226	methyltransferase
BF39_RS12605	COG4166	transmembrane transport
BF39_RS12610	COG4166	transmembrane transport
BF39_RS12615	COG4166	transmembrane transport
BF39_RS12620	COG1301	dicarboxylic acid transport
BF39_RS12625	COG1316	TRANSCRIPTIONal
BF39_RS12635	COG1595	DNA-templated transcription, initiation
BF39_RS12660	COG1131	(ABC) transporter
BF39_RS12670	COG0673	inositol 2-dehydrogenase activity
BF39_RS12675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF39_RS12680	COG0187	DNA topoisomerase II activity
BF39_RS12690	COG1832	CoA-binding protein
BF39_RS12695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF39_RS12700	COG0745	RESPONSE REGULATOR receiver
BF39_RS12715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BF39_RS12720	COG4841	protein insertion into membrane
BF39_RS12725	COG0824	Thioesterase
BF39_RS12755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_RS12765	COG2274	protein secretion by the type I secretion system
BF39_RS12770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF39_RS12800	COG2211	Major facilitator Superfamily
BF39_RS12810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF39_RS12825	COG0183	Belongs to the thiolase family
BF39_RS12830	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_RS12835	COG1268	BioY protein
BF39_RS12840	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_RS12885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS12895	COG5002	protein histidine kinase activity
BF39_RS12900	COG0400	carboxylic ester hydrolase activity
BF39_RS12905	COG0346	lactoylglutathione lyase activity
BF39_RS12910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_RS12915	COG0069	glutamate synthase activity
BF39_RS12920	COG1902	pentaerythritol trinitrate reductase activity
BF39_RS12925	COG1329	Transcriptional regulator
BF39_RS12930	COG0010	Belongs to the arginase family
BF39_RS12955	COG2226	methyltransferase
BF39_RS13010	COG4846	Membrane protein involved in cytochrome C biogenesis
BF39_RS13015	COG0785	Cytochrome C biogenesis protein
BF39_RS13025	COG0583	DNA-binding transcription factor activity
BF39_RS13030	COG1380	Effector of murein hydrolase LrgA
BF39_RS13035	COG1346	cytolysis
BF39_RS13050	COG0730	response to heat
BF39_RS13060	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_RS13060	COG3409	Peptidoglycan-binding domain 1 protein
BF39_RS13075	COG1132	(ABC) transporter
BF39_RS13080	COG1132	(ABC) transporter
BF39_RS13115	COG3639	organic phosphonate transmembrane transporter activity
BF39_RS13120	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BF39_RS13135	COG0737	Belongs to the 5'-nucleotidase family
BF39_RS13145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF39_RS13165	COG1695	Transcriptional regulator
BF39_RS13200	COG1388	LysM domain
BF39_RS13200	COG3409	Peptidoglycan-binding domain 1 protein
BF39_RS13200	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF39_RS13205	COG4824	toxin secretion phage lysis holin
BF39_RS13365	COG1595	DNA-templated transcription, initiation
BF39_RS13410	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BF39_RS13490	COG1396	sequence-specific DNA binding
BF39_RS13515	COG0174	glutamine synthetase
BF39_RS13520	COG0789	Transcriptional regulator
BF39_RS13525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF39_RS13535	COG2860	membrane
BF39_RS13540	COG0464	growth
BF39_RS13570	COG3584	3D domain protein
BF39_RS13570	COG1388	LysM domain
BF39_RS13575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF39_RS13575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF39_RS13575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF39_RS13580	COG1105	Belongs to the carbohydrate kinase PfkB family
BF39_RS13585	COG1349	DNA-binding transcription factor activity
BF39_RS13595	COG2322	membrane
BF39_RS13610	COG1113	amino acid transport
BF39_RS13620	COG1408	metallophosphoesterase
BF39_RS13625	COG2116	formate transmembrane transporter activity
BF39_RS13635	COG2217	Heavy metal translocating P-type atpase
BF39_RS13640	COG2608	mercury ion transmembrane transporter activity
BF39_RS13645	COG1937	Protein conserved in bacteria
BF39_RS13655	COG2819	hydrolase of the alpha beta superfamily
BF39_RS13660	COG1120	ATPase activity
BF39_RS13665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS13670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS13675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS13685	COG0708	Exodeoxyribonuclease III
BF39_RS13690	COG2169	Transcriptional regulator
BF39_RS13695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF39_RS13700	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF39_RS13710	COG2364	Membrane
BF39_RS13725	COG2267	carboxylic ester hydrolase activity
BF39_RS13730	COG0346	lactoylglutathione lyase activity
BF39_RS13735	COG5001	Diguanylate cyclase
BF39_RS13735	COG3300	MHYT domain
BF39_RS13755	COG1346	cytolysis
BF39_RS13760	COG1380	Effector of murein hydrolase LrgA
BF39_RS13765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS13770	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_RS13770	COG0596	Alpha beta hydrolase
BF39_RS13775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF39_RS13790	COG1404	Belongs to the peptidase S8 family
BF39_RS13795	COG3773	Cell wall hydrolase
BF39_RS13800	COG0562	UDP-galactopyranose mutase
BF39_RS13805	COG1368	sulfuric ester hydrolase activity
BF39_RS13810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF39_RS13820	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BF39_RS13845	COG1131	(ABC) transporter
BF39_RS13865	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF39_RS13870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF39_RS13875	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF39_RS13880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF39_RS13880	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF39_RS13890	COG2359	stage V sporulation protein S
BF39_RS13895	COG1692	metallophosphoesterase
BF39_RS13920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF39_RS13925	COG1426	Protein conserved in bacteria
BF39_RS13940	COG0300	oxidoreductase activity
BF39_RS13945	COG0612	Peptidase, M16
BF39_RS13950	COG0612	Peptidase, M16
BF39_RS13955	COG1079	Belongs to the binding-protein-dependent transport system permease family
BF39_RS13960	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF39_RS13965	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF39_RS13970	COG3845	ABC transporter
BF39_RS13975	COG1744	ABC transporter substrate-binding protein PnrA-like
BF39_RS13980	COG2188	Transcriptional regulator
BF39_RS13985	COG1674	ftsk spoiiie
BF39_RS13995	COG0740	serine-type endopeptidase activity
BF39_RS14000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF39_RS14015	COG0527	aspartate kinase activity
BF39_RS14020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF39_RS14025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF39_RS14030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF39_RS14035	COG1873	PFAM PRC-barrel domain
BF39_RS14040	COG0612	Peptidase, M16
BF39_RS14045	COG0726	polysaccharide deacetylase
BF39_RS14060	COG0196	riboflavin kinase activity
BF39_RS14065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF39_RS14075	COG1550	Protein conserved in bacteria
BF39_RS14085	COG1358	cellular component organization or biogenesis
BF39_RS14090	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF39_RS14095	COG0195	Participates in both transcription termination and antitermination
BF39_RS14115	COG0750	zinc metalloprotease
BF39_RS14125	COG4589	Belongs to the CDS family
BF39_RS14130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF39_RS14140	COG0528	UMP kinase activity
BF39_RS14170	COG4974	Belongs to the 'phage' integrase family
BF39_RS14180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF39_RS14190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF39_RS14230	COG1837	Belongs to the UPF0109 family
BF39_RS14240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF39_RS14250	COG0552	protein localization to endoplasmic reticulum
BF39_RS14255	COG1196	nuclear chromosome segregation
BF39_RS14265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF39_RS14270	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS14275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF39_RS14290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF39_RS14295	COG1461	Dihydroxyacetone kinase
BF39_RS14300	COG1302	Protein conserved in bacteria
BF39_RS14315	COG1564	THIamine pyrophosphokinase
BF39_RS14320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF39_RS14325	COG1162	GTPase activity
BF39_RS14330	COG2815	serine threonine protein kinase
BF39_RS14330	COG0515	serine threonine protein kinase
BF39_RS14335	COG0631	protein serine/threonine phosphatase activity
BF39_RS14345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF39_RS14345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF39_RS14355	COG0242	peptide deformylase activity
BF39_RS14360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF39_RS14365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF39_RS14385	COG1561	YicC-like family, N-terminal region
BF39_RS14390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF39_RS14400	COG0006	proline dipeptidase activity
BF39_RS14415	COG3069	C4-dicarboxylate transmembrane transporter activity
BF39_RS14480	COG0564	pseudouridine synthase activity
BF39_RS14500	COG3599	regulation of cell shape
BF39_RS14505	COG2302	S4 RNA-binding domain
BF39_RS14510	COG0762	integral membrane protein
BF39_RS14520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF39_RS14525	COG1496	oxidoreductase activity
BF39_RS14530	COG1873	PFAM PRC-barrel domain
BF39_RS14535	COG1191	sigma factor activity
BF39_RS14540	COG1191	sigma factor activity
BF39_RS14550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF39_RS14555	COG0849	cell division
BF39_RS14560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF39_RS14565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF39_RS14575	COG0772	Belongs to the SEDS family
BF39_RS14590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF39_RS14595	COG0768	penicillin binding
BF39_RS14600	COG0768	penicillin binding
BF39_RS14605	COG4839	cell division protein FtsL
BF39_RS14620	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF39_RS14635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BF39_RS14640	COG1399	metal-binding, possibly nucleic acid-binding protein
BF39_RS14690	COG4824	toxin secretion phage lysis holin
BF39_RS14785	COG4626	Terminase
BF39_RS14785	COG1802	Transcriptional regulator
BF39_RS14810	COG0582	viral genome integration into host DNA
BF39_RS14880	COG0756	dUTP diphosphatase activity
BF39_RS14890	COG1191	sigma factor activity
BF39_RS14915	COG1484	DNA-dependent DNA replication
BF39_RS14945	COG1396	sequence-specific DNA binding
BF39_RS14955	COG1396	sequence-specific DNA binding
BF39_RS14970	COG0582	viral genome integration into host DNA
BF39_RS14980	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF39_RS14985	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF39_RS14990	COG3314	Sporulation integral membrane protein YlbJ
BF39_RS15000	COG0742	ribosomal rna small subunit methyltransferase
BF39_RS15015	COG3679	Belongs to the UPF0342 family
BF39_RS15020	COG0406	alpha-ribazole phosphatase activity
BF39_RS15035	COG2340	Cysteine-rich secretory protein family
BF39_RS15050	COG3336	cytochrome c oxidase
BF39_RS15085	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF39_RS15090	COG0772	Belongs to the SEDS family
BF39_RS15100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF39_RS15105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF39_RS15115	COG4896	Protein conserved in bacteria
BF39_RS15130	COG1217	gtp-binding protein TYPA
BF39_RS15140	COG0483	inositol monophosphate 1-phosphatase activity
BF39_RS15160	COG1982	Orn Lys Arg decarboxylase major
BF39_RS15205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_RS15210	COG0022	dehydrogenase e1 component
BF39_RS15215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF39_RS15225	COG0242	peptide deformylase activity
BF39_RS15230	COG0561	phosphatase activity
BF39_RS15240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF39_RS15245	COG0569	domain protein
BF39_RS15265	COG0583	DNA-binding transcription factor activity
BF39_RS15270	COG0517	IMP dehydrogenase activity
BF39_RS15280	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF39_RS15290	COG4703	Protein of unknown function (DUF1797)
BF39_RS15305	COG2200	EAL domain
BF39_RS15310	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS15315	COG1408	metallophosphoesterase
BF39_RS15325	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF39_RS15365	COG2814	Major facilitator Superfamily
BF39_RS15390	COG3209	COG3209 Rhs family protein
BF39_RS15400	COG2205	protein histidine kinase activity
BF39_RS15410	COG0436	Aminotransferase
BF39_RS15415	COG1609	Transcriptional regulator
BF39_RS15420	COG3833	ABC-type maltose transport systems, permease component
BF39_RS15425	COG1175	transmembrane transport
BF39_RS15430	COG2182	Extracellular solute-binding protein
BF39_RS15440	COG0366	Alpha amylase catalytic
BF39_RS15445	COG3842	ATPase activity
BF39_RS15485	COG0183	Belongs to the thiolase family
BF39_RS15525	COG1695	Transcriptional regulator
BF39_RS15530	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS15540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BF39_RS15550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF39_RS15555	COG0436	Aminotransferase
BF39_RS15575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BF39_RS15595	COG2199	diguanylate cyclase activity
BF39_RS15600	COG0778	Nitroreductase
BF39_RS15625	COG1263	PTS System
BF39_RS15625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_RS15625	COG2190	(PTS) system
BF39_RS15630	COG3711	transcriptional antiterminator
BF39_RS15640	COG2188	Transcriptional regulator
BF39_RS15680	COG1547	Domain of unknown function (DUF309)
BF39_RS15685	COG0456	acetyltransferase
BF39_RS15695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF39_RS15700	COG4086	secreted protein
BF39_RS15705	COG0561	phosphatase activity
BF39_RS15710	COG0697	spore germination
BF39_RS15725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_RS15750	COG0733	neurotransmitter:sodium symporter activity
BF39_RS15770	COG1686	Belongs to the peptidase S11 family
BF39_RS15775	COG1725	Transcriptional regulator
BF39_RS15780	COG1131	(ABC) transporter
BF39_RS15800	COG1846	Transcriptional regulator
BF39_RS15815	COG0598	Magnesium transport protein CorA
BF39_RS15840	COG4974	Belongs to the 'phage' integrase family
BF39_RS15850	COG0735	belongs to the Fur family
BF39_RS15855	COG1300	Membrane
BF39_RS15875	COG0667	Aldo Keto reductase
BF39_RS15880	COG0656	L-ascorbic acid biosynthetic process
BF39_RS15885	COG0456	acetyltransferase
BF39_RS15885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF39_RS15895	COG0737	Belongs to the 5'-nucleotidase family
BF39_RS15895	COG1525	nuclease
BF39_RS15895	COG4085	toxin activity
BF39_RS15905	COG0596	Alpha beta hydrolase
BF39_RS15910	COG2056	Na+-H+ antiporter family
BF39_RS15915	COG1609	Transcriptional regulator
BF39_RS15920	COG0456	acetyltransferase
BF39_RS15925	COG1073	alpha beta
BF39_RS15940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF39_RS15940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF39_RS15945	COG0307	riboflavin synthase, alpha
BF39_RS15970	COG4106	trans-aconitate 2-methyltransferase activity
BF39_RS15975	COG2226	methyltransferase
BF39_RS15975	COG1073	alpha beta
BF39_RS15990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF39_RS16000	COG1757	Na H antiporter
BF39_RS16005	COG0737	Belongs to the 5'-nucleotidase family
BF39_RS16015	COG1522	sequence-specific DNA binding
BF39_RS16035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF39_RS16045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BF39_RS16060	COG0300	oxidoreductase activity
BF39_RS16065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS16075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_RS16080	COG1760	l-serine dehydratase
BF39_RS16085	COG1760	l-serine dehydratase
BF39_RS16105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BF39_RS16115	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF39_RS16120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS16135	COG1376	ErfK ybiS ycfS ynhG family protein
BF39_RS16140	COG4129	membrane
BF39_RS16145	COG1126	abc transporter atp-binding protein
BF39_RS16150	COG0765	amino acid transport
BF39_RS16155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_RS16180	COG0772	Belongs to the SEDS family
BF39_RS16190	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF39_RS16195	COG0022	dehydrogenase e1 component
BF39_RS16200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF39_RS16205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF39_RS16220	COG0280	phosphate acetyltransferase
BF39_RS16230	COG3829	transcription factor binding
BF39_RS16230	COG3290	protein histidine kinase activity
BF39_RS16240	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_RS16245	COG3093	addiction module antidote protein HigA
BF39_RS16255	COG0745	RESPONSE REGULATOR receiver
BF39_RS16260	COG0750	zinc metalloprotease
BF39_RS16265	COG0497	DNA recombination
BF39_RS16275	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF39_RS16285	COG0142	geranyltranstransferase activity
BF39_RS16310	COG1302	Protein conserved in bacteria
BF39_RS16315	COG0439	Biotin carboxylase
BF39_RS16320	COG0511	ligase activity, forming carbon-carbon bonds
BF39_RS16365	COG3854	ATPases associated with a variety of cellular activities
BF39_RS16390	COG0006	proline dipeptidase activity
BF39_RS16405	COG3872	metal-dependent enzyme
BF39_RS16415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF39_RS16435	COG0095	Lipoate-protein ligase
BF39_RS16440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_RS16445	COG1609	Transcriptional regulator
BF39_RS16455	COG2076	Multidrug Resistance protein
BF39_RS16460	COG2076	Multidrug Resistance protein
BF39_RS16500	COG1131	(ABC) transporter
BF39_RS16505	COG1725	Transcriptional regulator
BF39_RS16535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF39_RS16590	COG4970	Tfp pilus assembly protein FimT
BF39_RS16600	COG1459	type II secretion system
BF39_RS16605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF39_RS16655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF39_RS16660	COG0646	methionine synthase
BF39_RS16660	COG1410	methionine synthase
BF39_RS16665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF39_RS16665	COG0646	methionine synthase
BF39_RS16675	COG0626	cystathionine gamma-synthase activity
BF39_RS16680	COG0626	cystathionine gamma-synthase activity
BF39_RS16705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS16715	COG1940	carbohydrate kinase activity
BF39_RS16720	COG4483	Protein conserved in bacteria
BF39_RS16725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF39_RS16730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF39_RS16740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF39_RS16745	COG0704	Plays a role in the regulation of phosphate uptake
BF39_RS16755	COG0581	inorganic phosphate transmembrane transporter activity
BF39_RS16760	COG0573	inorganic phosphate transmembrane transporter activity
BF39_RS16765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF39_RS16770	COG0768	penicillin binding
BF39_RS16775	COG0477	Major facilitator Superfamily
BF39_RS16780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF39_RS16805	COG0735	belongs to the Fur family
BF39_RS16810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF39_RS16815	COG1121	(ABC) transporter
BF39_RS16820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS16850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF39_RS16855	COG2384	SAM-dependent methyltransferase
BF39_RS16860	COG2010	Cytochrome c
BF39_RS16865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF39_RS16870	COG0358	DNA primase activity
BF39_RS16890	COG0517	IMP dehydrogenase activity
BF39_RS16905	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF39_RS16910	COG0295	cytidine deaminase activity
BF39_RS16915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF39_RS16925	COG1480	7TM receptor with intracellular HD hydrolase
BF39_RS16930	COG1702	phosphate starvation-inducible protein PhoH
BF39_RS16950	COG1610	YqeY-like protein
BF39_RS16955	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BF39_RS16960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF39_RS16965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF39_RS16995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF39_RS17000	COG1733	regulation of RNA biosynthetic process
BF39_RS17025	COG1466	dna polymerase III delta subunit
BF39_RS17035	COG2333	competence protein COMEC
BF39_RS17035	COG0658	competence protein
BF39_RS17040	COG2131	deaminase
BF39_RS17045	COG1596	polysaccharide export
BF39_RS17045	COG1555	photosystem II stabilization
BF39_RS17050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_RS17055	COG2226	methyltransferase
BF39_RS17060	COG0799	negative regulation of ribosome biogenesis
BF39_RS17065	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF39_RS17075	COG1534	Rna-binding protein
BF39_RS17085	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF39_RS17090	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF39_RS17115	COG1595	DNA-templated transcription, initiation
BF39_RS17125	COG0778	Nitroreductase
BF39_RS17130	COG2357	RelA SpoT domain protein
BF39_RS17140	COG1785	Belongs to the alkaline phosphatase family
BF39_RS17150	COG2267	carboxylic ester hydrolase activity
BF39_RS17185	COG1404	Belongs to the peptidase S8 family
BF39_RS17190	COG3186	Phenylalanine-4-hydroxylase
BF39_RS17200	COG2514	catechol 2,3-dioxygenase activity
BF39_RS17205	COG2514	catechol 2,3-dioxygenase activity
BF39_RS17210	COG2259	Doxx family
BF39_RS17250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS17260	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS17260	COG1454	alcohol dehydrogenase
BF39_RS17265	COG0626	cystathionine gamma-synthase activity
BF39_RS17270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF39_RS17295	COG0768	penicillin binding
BF39_RS17310	COG0826	peptidase U32
BF39_RS17315	COG0826	peptidase U32
BF39_RS17320	COG4122	O-methyltransferase activity
BF39_RS17325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF39_RS17345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF39_RS17355	COG0628	permease
BF39_RS17375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF39_RS17385	COG0482	sulfurtransferase activity
BF39_RS17390	COG1104	cysteine desulfurase activity
BF39_RS17395	COG1959	2 iron, 2 sulfur cluster binding
BF39_RS17400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF39_RS17410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF39_RS17435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF39_RS17445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF39_RS17445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF39_RS17450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF39_RS17455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF39_RS17455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF39_RS17465	COG2244	polysaccharide biosynthetic process
BF39_RS17470	COG2323	membrane
BF39_RS17480	COG1862	Preprotein translocase
BF39_RS17510	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF39_RS17520	COG0697	spore germination
BF39_RS17525	COG0697	spore germination
BF39_RS17530	COG0640	Transcriptional regulator
BF39_RS17555	COG0157	Belongs to the NadC ModD family
BF39_RS17560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF39_RS17565	COG1104	cysteine desulfurase activity
BF39_RS17570	COG1827	regulation of RNA biosynthetic process
BF39_RS17575	COG2258	MOSC domain
BF39_RS17580	COG0077	Prephenate dehydratase
BF39_RS17585	COG0577	efflux transmembrane transporter activity
BF39_RS17590	COG0577	efflux transmembrane transporter activity
BF39_RS17595	COG1136	(ABC) transporter
BF39_RS17600	COG5002	protein histidine kinase activity
BF39_RS17610	COG0745	RESPONSE REGULATOR receiver
BF39_RS17615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF39_RS17620	COG3290	protein histidine kinase activity
BF39_RS17630	COG2868	ribosomal protein
BF39_RS17640	COG1530	ribonuclease E activity
BF39_RS17645	COG1994	Peptidase M50
BF39_RS17650	COG0739	heme binding
BF39_RS17655	COG2894	cell division
BF39_RS17675	COG1077	Cell shape determining protein MreB Mrl
BF39_RS17695	COG0285	dihydrofolate synthase activity
BF39_RS17700	COG0525	valine-tRNA ligase activity
BF39_RS17710	COG1388	LysM domain
BF39_RS17720	COG0113	porphobilinogen synthase activity
BF39_RS17725	COG1587	Uroporphyrinogen-III synthase
BF39_RS17735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF39_RS17745	COG1846	Transcriptional regulator
BF39_RS17750	COG1764	response to oxidative stress
BF39_RS17765	COG1067	ATP-dependent peptidase activity
BF39_RS17765	COG0470	DNA polymerase III
BF39_RS17815	COG0622	Phosphoesterase
BF39_RS17830	COG5401	PFAM Sporulation and spore germination
BF39_RS17850	COG1309	transcriptional regulator
BF39_RS17865	COG2197	response regulator
BF39_RS17870	COG2233	PERMEase
BF39_RS17880	COG0402	S-adenosylhomocysteine deaminase activity
BF39_RS17885	COG0402	S-adenosylhomocysteine deaminase activity
BF39_RS17895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_RS17905	COG0444	Belongs to the ABC transporter superfamily
BF39_RS17910	COG4608	Belongs to the ABC transporter superfamily
BF39_RS17915	COG3275	phosphorelay sensor kinase activity
BF39_RS17920	COG3279	Response regulator of the LytR AlgR family
BF39_RS17935	COG1983	PspC domain protein
BF39_RS17940	COG1396	sequence-specific DNA binding
BF39_RS17945	COG0697	spore germination
BF39_RS17955	COG1959	2 iron, 2 sulfur cluster binding
BF39_RS17960	COG1668	transmembrane transport
BF39_RS17965	COG4152	abc transporter atp-binding protein
BF39_RS17970	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF39_RS17980	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF39_RS17985	COG1876	peptidase activity
BF39_RS17990	COG0824	Thioesterase
BF39_RS17995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF39_RS18000	COG1053	succinate dehydrogenase
BF39_RS18005	COG2009	succinate dehydrogenase
BF39_RS18010	COG1719	4-vinyl reductase, 4VR
BF39_RS18020	COG3118	belongs to the thioredoxin family
BF39_RS18025	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF39_RS18030	COG2086	electron transfer activity
BF39_RS18035	COG1024	Enoyl-CoA hydratase
BF39_RS18040	COG1309	transcriptional regulator
BF39_RS18045	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_RS18065	COG2318	DinB family
BF39_RS18095	COG1131	(ABC) transporter
BF39_RS18100	COG2205	protein histidine kinase activity
BF39_RS18105	COG0745	RESPONSE REGULATOR receiver
BF39_RS18115	COG4895	conserved protein (DUF2196)
BF39_RS18120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF39_RS18135	COG4509	Sortase family
BF39_RS18140	COG1120	ATPase activity
BF39_RS18155	COG5386	Cell surface protein
BF39_RS18165	COG5386	Cell surface protein
BF39_RS18170	COG1114	Component of the transport system for branched-chain amino acids
BF39_RS18175	COG1187	pseudouridine synthase activity
BF39_RS18190	COG1796	DNA polymerase
BF39_RS18190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF39_RS18195	COG1286	toxin biosynthetic process
BF39_RS18240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF39_RS18250	COG1418	mRNA catabolic process
BF39_RS18275	COG2814	Major facilitator Superfamily
BF39_RS18280	COG1566	PFAM secretion protein HlyD family protein
BF39_RS18285	COG1309	transcriptional regulator
BF39_RS18290	COG1363	Peptidase, m42
BF39_RS18315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF39_RS18325	COG1484	DNA-dependent DNA replication
BF39_RS18330	COG3611	Membrane attachment protein
BF39_RS18340	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF39_RS18345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF39_RS18350	COG0237	dephospho-CoA kinase activity
BF39_RS18355	COG1971	Probably functions as a manganese efflux pump
BF39_RS18365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF39_RS18365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF39_RS18370	COG5002	protein histidine kinase activity
BF39_RS18375	COG0745	RESPONSE REGULATOR receiver
BF39_RS18395	COG0538	isocitrate dehydrogenase activity
BF39_RS18400	COG0372	Belongs to the citrate synthase family
BF39_RS18415	COG0628	permease
BF39_RS18420	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF39_RS18445	COG1725	Transcriptional regulator
BF39_RS18450	COG0281	malic enzyme
BF39_RS18455	COG0587	DNA-directed DNA polymerase activity
BF39_RS18470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF39_RS18490	COG4109	DRTGG domain
BF39_RS18505	COG0006	proline dipeptidase activity
BF39_RS18540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS18545	COG0662	Cupin 2, conserved barrel domain protein
BF39_RS18555	COG1476	TRANSCRIPTIONal
BF39_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS18575	COG0589	response to stress
BF39_RS18615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS18635	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF39_RS18640	COG0827	DNA restriction-modification system
BF39_RS18645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF39_RS18650	COG3874	Sporulation protein YtfJ
BF39_RS18665	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF39_RS18675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF39_RS18690	COG1104	cysteine desulfurase activity
BF39_RS18700	COG0583	DNA-binding transcription factor activity
BF39_RS18705	COG0697	spore germination
BF39_RS18715	COG1956	GAF domain-containing protein
BF39_RS18720	COG0626	cystathionine gamma-synthase activity
BF39_RS18750	COG1595	DNA-templated transcription, initiation
BF39_RS18760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF39_RS18765	COG0454	-acetyltransferase
BF39_RS18770	COG0517	IMP dehydrogenase activity
BF39_RS18775	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF39_RS18785	COG0745	RESPONSE REGULATOR receiver
BF39_RS18795	COG0666	response to abiotic stimulus
BF39_RS18830	COG1609	Transcriptional regulator
BF39_RS18840	COG4851	CamS sex pheromone cAM373 precursor
BF39_RS18845	COG3118	belongs to the thioredoxin family
BF39_RS18855	COG2309	aminopeptidase activity
BF39_RS18875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS18900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_RS18905	COG4848	Belongs to the UPF0354 family
BF39_RS18910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_RS18915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF39_RS18920	COG1363	Peptidase, m42
BF39_RS18930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS18945	COG0510	thiamine kinase activity
BF39_RS18950	COG1523	belongs to the glycosyl hydrolase 13 family
BF39_RS18965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_RS18970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_RS18975	COG1349	DNA-binding transcription factor activity
BF39_RS18980	COG1187	pseudouridine synthase activity
BF39_RS18985	COG2244	polysaccharide biosynthetic process
BF39_RS18990	COG2081	HI0933 family
BF39_RS18995	COG2814	Major facilitator Superfamily
BF39_RS19005	COG3832	glyoxalase III activity
BF39_RS19025	COG1329	Transcriptional regulator
BF39_RS19035	COG4975	Glucose uptake
BF39_RS19050	COG0314	molybdopterin synthase activity
BF39_RS19055	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF39_RS19060	COG0303	'Molybdopterin
BF39_RS19070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_RS19095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_RS19105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF39_RS19150	COG2814	Major facilitator Superfamily
BF39_RS19155	COG0475	glutathione-regulated potassium exporter activity
BF39_RS19160	COG0490	domain, Protein
BF39_RS19165	COG0582	viral genome integration into host DNA
BF39_RS19175	COG1136	(ABC) transporter
BF39_RS19195	COG1242	4 iron, 4 sulfur cluster binding
BF39_RS19200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF39_RS19205	COG1131	(ABC) transporter
BF39_RS19215	COG1794	racemase activity, acting on amino acids and derivatives
BF39_RS19235	COG2267	carboxylic ester hydrolase activity
BF39_RS19240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF39_RS19245	COG0671	phosphoesterase, PA-phosphatase related
BF39_RS19250	COG0438	transferase activity, transferring glycosyl groups
BF39_RS19260	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF39_RS19315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF39_RS19320	COG5002	protein histidine kinase activity
BF39_RS19325	COG4191	Histidine kinase
BF39_RS19330	COG2267	carboxylic ester hydrolase activity
BF39_RS19350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF39_RS19355	COG1116	anion transmembrane transporter activity
BF39_RS19360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_RS19385	COG0494	nUDIX hydrolase
BF39_RS19415	COG0288	reversible hydration of carbon dioxide
BF39_RS19420	COG1271	oxidase subunit
BF39_RS19425	COG1294	oxidase, subunit
BF39_RS19445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS19470	COG1842	Phage shock protein A
BF39_RS19505	COG5002	protein histidine kinase activity
BF39_RS19510	COG0745	RESPONSE REGULATOR receiver
BF39_RS19540	COG1597	lipid kinase activity
BF39_RS19575	COG0586	Pfam SNARE associated Golgi protein
BF39_RS19585	COG0577	efflux transmembrane transporter activity
BF39_RS19590	COG1136	(ABC) transporter
BF39_RS19595	COG2207	Transcriptional regulator
BF39_RS19595	COG3708	Transcriptional regulator
BF39_RS19600	COG0745	RESPONSE REGULATOR receiver
BF39_RS19605	COG2205	protein histidine kinase activity
BF39_RS19610	COG0577	efflux transmembrane transporter activity
BF39_RS19615	COG0577	efflux transmembrane transporter activity
BF39_RS19620	COG0577	efflux transmembrane transporter activity
BF39_RS19625	COG1136	(ABC) transporter
BF39_RS19645	COG2188	Transcriptional regulator
BF39_RS19665	COG3964	amidohydrolase
BF39_RS19695	COG4948	Mandelate Racemase Muconate Lactonizing
BF39_RS19705	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF39_RS19710	COG0596	Alpha beta hydrolase
BF39_RS19715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF39_RS19720	COG1169	isochorismate synthase
BF39_RS19725	COG1575	Belongs to the MenA family. Type 1 subfamily
BF39_RS19730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF39_RS19755	COG0058	SHG alpha-glucan phosphorylase activity
BF39_RS19760	COG0297	glycogen (starch) synthase activity
BF39_RS19765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF39_RS19875	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF39_RS19910	COG1285	pathogenesis
BF39_RS19915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF39_RS19925	COG0166	Belongs to the GPI family
BF39_RS19935	COG2155	Conserved Protein
BF39_RS19940	COG1098	S1 RNA binding domain
BF39_RS19945	COG0436	Aminotransferase
BF39_RS19950	COG1522	sequence-specific DNA binding
BF39_RS19955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF39_RS19960	COG2267	carboxylic ester hydrolase activity
BF39_RS19970	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF39_RS19990	COG5018	Exonuclease
BF39_RS19995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF39_RS20015	COG2050	protein possibly involved in aromatic compounds catabolism
BF39_RS20025	COG1268	BioY protein
BF39_RS20035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF39_RS20040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF39_RS20055	COG3584	3D domain protein
BF39_RS20070	COG1252	NADH dehydrogenase
BF39_RS20085	COG3708	Transcriptional regulator
BF39_RS20100	COG1683	Conserved Protein
BF39_RS20120	COG0316	Belongs to the HesB IscA family
BF39_RS20135	COG1252	NADH dehydrogenase
BF39_RS20150	COG0390	transport system, permease component
BF39_RS20155	COG2824	Alkylphosphonate utilization operon protein PhnA
BF39_RS20195	COG4837	Protein of unknown function (DUF1462)
BF39_RS20200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF39_RS20210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF39_RS20215	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF39_RS20230	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_RS20235	COG0647	UMP catabolic process
BF39_RS20245	COG2445	Protein of unknown function DUF86
BF39_RS20250	COG1494	fructose-1,6-bisphosphatase
BF39_RS20270	COG4470	Protein conserved in bacteria
BF39_RS20280	COG0789	Transcriptional regulator
BF39_RS20285	COG4377	Putative membrane peptidase family (DUF2324)
BF39_RS20310	COG0739	heme binding
BF39_RS20320	COG3377	Domain of unknown function (DUF1805)
BF39_RS20325	COG0737	Belongs to the 5'-nucleotidase family
BF39_RS20335	COG1695	Transcriptional regulator
BF39_RS20350	COG0719	Fe-S assembly protein
BF39_RS20355	COG0822	iron-sulfur transferase activity
BF39_RS20360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF39_RS20365	COG0719	Fe-S assembly protein
BF39_RS20370	COG0396	ATPase activity
BF39_RS20375	COG1464	Belongs to the NlpA lipoprotein family
BF39_RS20380	COG1464	Belongs to the NlpA lipoprotein family
BF39_RS20385	COG2011	ABC-type metal ion transport system permease component
BF39_RS20390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF39_RS20405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_RS20410	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF39_RS20420	COG1393	Belongs to the ArsC family
BF39_RS20470	COG0039	L-malate dehydrogenase activity
BF39_RS20495	COG1309	transcriptional regulator
BF39_RS20500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS20505	COG1960	acyl-CoA dehydrogenase activity
BF39_RS20515	COG0183	Belongs to the thiolase family
BF39_RS20520	COG1024	Enoyl-CoA hydratase
BF39_RS20520	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF39_RS20530	COG1686	Belongs to the peptidase S11 family
BF39_RS20545	COG0011	TIGRFAM Protein of
BF39_RS20550	COG0840	transmembrane signaling receptor activity
BF39_RS20570	COG2814	Major facilitator Superfamily
BF39_RS20575	COG0531	amino acid
BF39_RS20585	COG0706	membrane insertase activity
BF39_RS20595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS20630	COG0586	Pfam SNARE associated Golgi protein
BF39_RS20640	COG1376	ErfK ybiS ycfS ynhG family protein
BF39_RS20645	COG0745	RESPONSE REGULATOR receiver
BF39_RS20650	COG5002	protein histidine kinase activity
BF39_RS20675	COG2151	metal-sulfur cluster biosynthetic enzyme
BF39_RS20680	COG3227	Zinc metalloprotease (Elastase)
BF39_RS20685	COG1741	Belongs to the pirin family
BF39_RS20700	COG0475	glutathione-regulated potassium exporter activity
BF39_RS20705	COG0490	domain, Protein
BF39_RS20715	COG1115	amino acid carrier protein
BF39_RS20720	COG0783	Belongs to the Dps family
BF39_RS20735	COG1611	Belongs to the LOG family
BF39_RS20750	COG2311	Membrane
BF39_RS20760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS20765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS20770	COG1115	amino acid carrier protein
BF39_RS20775	COG1115	amino acid carrier protein
BF39_RS20780	COG2910	NAD(P)H-binding
BF39_RS20795	COG0656	L-ascorbic acid biosynthetic process
BF39_RS20800	COG2814	Major facilitator Superfamily
BF39_RS20805	COG1733	regulation of RNA biosynthetic process
BF39_RS20815	COG1252	NADH dehydrogenase
BF39_RS20820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF39_RS20825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF39_RS20835	COG0840	transmembrane signaling receptor activity
BF39_RS20835	COG3290	protein histidine kinase activity
BF39_RS20845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF39_RS20850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF39_RS20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF39_RS20915	COG0557	exoribonuclease II activity
BF39_RS20920	COG1647	Serine aminopeptidase, S33
BF39_RS20925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF39_RS20930	COG1346	cytolysis
BF39_RS21030	COG4695	Portal protein
BF39_RS21055	COG4974	Belongs to the 'phage' integrase family
BF39_RS21065	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF39_RS21070	COG0149	triose-phosphate isomerase activity
BF39_RS21080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF39_RS21095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF39_RS21120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_RS21135	COG2323	membrane
BF39_RS21140	COG0740	serine-type endopeptidase activity
BF39_RS21145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF39_RS21155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF39_RS21165	COG1051	belongs to the nudix hydrolase family
BF39_RS21175	COG0492	ferredoxin-NADP+ reductase activity
BF39_RS21180	COG0457	Tetratricopeptide repeat
BF39_RS21185	COG0110	maltose O-acetyltransferase activity
BF39_RS21205	COG1950	PFAM Membrane protein of
BF39_RS21215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF39_RS21220	COG0556	nucleotide-excision repair
BF39_RS21240	COG0789	Transcriptional regulator
BF39_RS21265	COG2855	membrane
BF39_RS21270	COG0583	DNA-binding transcription factor activity
BF39_RS21280	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF39_RS21285	COG0488	(ABC) transporter
BF39_RS21295	COG1132	(ABC) transporter
BF39_RS21300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF39_RS21305	COG0793	Belongs to the peptidase S41A family
BF39_RS21305	COG3409	Peptidoglycan-binding domain 1 protein
BF39_RS21310	COG2177	Part of the ABC transporter FtsEX involved in
BF39_RS21315	COG2884	Cell division ATP-binding protein ftsE
BF39_RS21330	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF39_RS21335	COG0653	protein targeting
BF39_RS21340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF39_RS21345	COG1278	Cold shock
BF39_RS21350	COG1040	competence protein
BF39_RS21355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF39_RS21360	COG1388	LysM domain
BF39_RS21360	COG0791	NLP P60 protein
BF39_RS21365	COG1733	regulation of RNA biosynthetic process
BF39_RS21375	COG1307	EDD domain protein, DegV family
BF39_RS21380	COG1739	Uncharacterized protein family UPF0029
BF39_RS21385	COG1316	TRANSCRIPTIONal
BF39_RS21390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF39_RS21395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF39_RS21400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF39_RS21410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF39_RS21410	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF39_RS21425	COG3394	polysaccharide catabolic process
BF39_RS21430	COG1486	melibiose metabolic process
BF39_RS21435	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF39_RS21440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF39_RS21450	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF39_RS21455	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF39_RS21460	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF39_RS21470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF39_RS21475	COG1301	dicarboxylic acid transport
BF39_RS21485	COG0346	lactoylglutathione lyase activity
BF39_RS21490	COG1511	domain protein
BF39_RS21495	COG0583	DNA-binding transcription factor activity
BF39_RS21500	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF39_RS21515	COG1271	oxidase subunit
BF39_RS21520	COG1294	oxidase, subunit
BF39_RS21525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF39_RS21545	COG2389	metal-binding protein
BF39_RS21555	COG1368	sulfuric ester hydrolase activity
BF39_RS21570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS21580	COG1215	transferase activity, transferring glycosyl groups
BF39_RS21590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF39_RS21595	COG3584	3D domain protein
BF39_RS21595	COG1388	LysM domain
BF39_RS21620	COG4715	Zinc finger, swim domain protein
BF39_RS21625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF39_RS21665	COG0577	efflux transmembrane transporter activity
BF39_RS21670	COG1136	(ABC) transporter
BF39_RS21705	COG5002	protein histidine kinase activity
BF39_RS21710	COG0745	RESPONSE REGULATOR receiver
BF39_RS21715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF39_RS21735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF39_RS21740	COG1134	teichoic acid transport
BF39_RS21745	COG1682	transport, permease protein
BF39_RS21750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF39_RS21795	COG1609	Transcriptional regulator
BF39_RS21810	COG0739	heme binding
BF39_RS21825	COG3279	Response regulator of the LytR AlgR family
BF39_RS21830	COG4555	ABC transporter
BF39_RS21835	COG2385	sporulation resulting in formation of a cellular spore
BF39_RS21850	COG4836	Membrane
BF39_RS21855	COG1007	ATP synthesis coupled electron transport
BF39_RS21860	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF39_RS21865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF39_RS21875	COG0839	Belongs to the complex I subunit 6 family
BF39_RS21890	COG0649	NAD binding
BF39_RS21895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF39_RS21910	COG3300	MHYT domain
BF39_RS21910	COG5001	Diguanylate cyclase
BF39_RS21960	COG0356	it plays a direct role in the translocation of protons across the membrane
BF39_RS21995	COG0698	ribose 5-phosphate isomerase
BF39_RS22005	COG2190	(PTS) system
BF39_RS22010	COG2259	Doxx family
BF39_RS22015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF39_RS22030	COG0009	L-threonylcarbamoyladenylate synthase
BF39_RS22045	COG2890	protein-(glutamine-N5) methyltransferase activity
BF39_RS22065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF39_RS22070	COG1494	fructose-1,6-bisphosphatase
BF39_RS22090	COG4821	SIS domain
BF39_RS22100	COG3343	RNA polymerase activity
BF39_RS22110	COG1960	acyl-CoA dehydrogenase activity
BF39_RS22115	COG1960	acyl-CoA dehydrogenase activity
BF39_RS22120	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF39_RS22125	COG0183	Belongs to the thiolase family
BF39_RS22130	COG0247	lactate metabolic process
BF39_RS22130	COG2181	nitrate reductase activity
BF39_RS22135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_RS22145	COG5001	Diguanylate cyclase
BF39_RS22145	COG3300	MHYT domain
BF39_RS22160	COG2197	response regulator
BF39_RS22165	COG4585	Histidine kinase
BF39_RS22170	COG0842	Transport permease protein
BF39_RS22175	COG1131	(ABC) transporter
BF39_RS22180	COG0024	Methionine aminopeptidase
BF39_RS22200	COG2234	aminopeptidase activity
BF39_RS22220	COG1595	DNA-templated transcription, initiation
BF39_RS22225	COG0018	arginyl-trna synthetase
BF39_RS22230	COG4506	Protein conserved in bacteria
BF39_RS22235	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF39_RS22255	COG0010	Belongs to the arginase family
BF39_RS22265	COG2814	Major facilitator Superfamily
BF39_RS22270	COG0789	Transcriptional regulator
BF39_RS22275	COG0584	glycerophosphoryl diester phosphodiesterase
BF39_RS22280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_RS22290	COG1994	Peptidase M50
BF39_RS22300	COG1078	dGTPase activity
BF39_RS22305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS22310	COG1120	ATPase activity
BF39_RS22315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS22320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS22325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS22345	COG0095	Lipoate-protein ligase
BF39_RS22350	COG0280	phosphate acetyltransferase
BF39_RS22365	COG3773	Cell wall hydrolase
BF39_RS22375	COG2363	Small membrane protein
BF39_RS22385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF39_RS22390	COG2233	PERMEase
BF39_RS22395	COG0561	phosphatase activity
BF39_RS22400	COG2814	Major facilitator Superfamily
BF39_RS22410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF39_RS22415	COG1131	(ABC) transporter
BF39_RS22420	COG2755	lipolytic protein G-D-S-L family
BF39_RS22425	COG1609	Transcriptional regulator
BF39_RS22435	COG0460	homoserine dehydrogenase
BF39_RS22445	COG2873	o-acetylhomoserine
BF39_RS22455	COG1011	Hydrolase
BF39_RS22460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF39_RS22470	COG2197	response regulator
BF39_RS22480	COG0351	phosphomethylpyrimidine kinase
BF39_RS22485	COG3706	GGDEF domain
BF39_RS22490	COG2879	small protein
BF39_RS22495	COG1966	Carbon starvation protein
BF39_RS22500	COG3279	Response regulator of the LytR AlgR family
BF39_RS22505	COG0477	Major facilitator Superfamily
BF39_RS22530	COG0840	transmembrane signaling receptor activity
BF39_RS22540	COG1607	acyl-coa hydrolase
BF39_RS22555	COG0488	(ABC) transporter
BF39_RS22580	COG0463	Glycosyl transferase, family 2
BF39_RS22585	COG1309	transcriptional regulator
BF39_RS22590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF39_RS22595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF39_RS22595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF39_RS22600	COG0628	permease
BF39_RS22615	COG3279	Response regulator of the LytR AlgR family
BF39_RS22620	COG3275	phosphorelay sensor kinase activity
BF39_RS22625	COG2814	Major facilitator Superfamily
BF39_RS22630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF39_RS22635	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF39_RS22640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF39_RS22660	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF39_RS22665	COG1272	protein, Hemolysin III
BF39_RS22685	COG0516	GMP reductase activity
BF39_RS22690	COG1164	Oligoendopeptidase f
BF39_RS22710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF39_RS22715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF39_RS22720	COG4853	Protein conserved in bacteria
BF39_RS22725	COG4863	YycH protein
BF39_RS22730	COG5002	protein histidine kinase activity
BF39_RS22735	COG0745	RESPONSE REGULATOR receiver
BF39_RS22765	COG0305	Participates in initiation and elongation during chromosome replication
BF39_RS22775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF39_RS22780	COG4241	membrane
BF39_RS22790	COG0629	single-stranded DNA binding
BF39_RS22800	COG0012	GTP binding
BF39_RS22805	COG4481	Protein conserved in bacteria
BF39_RS22810	COG0668	transmembrane transport
BF39_RS22820	COG1475	DNA binding
BF39_RS22825	COG1192	Involved in chromosome partitioning
BF39_RS22850	COG1847	R3H domain protein
BF39_RS22855	COG0706	membrane insertase activity
BF39_RS22865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BF39_RS22875	COG0592	DNA-directed DNA polymerase activity
BF39_RS22880	COG2501	S4 domain
BF39_RS22890	COG0187	DNA topoisomerase II activity
BF39_RS22895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF39_RS22920	COG0516	GMP reductase activity
BF39_RS22920	COG0517	IMP dehydrogenase activity
BF39_RS22925	COG1686	Belongs to the peptidase S11 family
BF39_RS22955	COG1428	Deoxynucleoside kinase
BF39_RS22960	COG1428	Deoxynucleoside kinase
BF39_RS22965	COG1335	isochorismatase
BF39_RS22975	COG0590	tRNA wobble adenosine to inosine editing
BF39_RS22980	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF39_RS23025	COG1982	Orn Lys Arg decarboxylase major
BF39_RS23035	COG0470	DNA polymerase III
BF39_RS23040	COG1774	PSP1 C-terminal conserved region
BF39_RS23050	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF39_RS23060	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF39_RS23065	COG2002	toxin-antitoxin pair type II binding
BF39_RS23070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_RS23070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF39_RS23075	COG0084	hydrolase, TatD family'
BF39_RS23080	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF39_RS23095	COG4466	Protein conserved in bacteria
BF39_RS23110	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF39_RS23115	COG0251	oxidation-reduction process
BF39_RS23145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF39_RS23150	COG2002	toxin-antitoxin pair type II binding
BF39_RS23155	COG2244	polysaccharide biosynthetic process
BF39_RS23160	COG3956	TIGRFAM MazG family protein
BF39_RS23165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF39_RS23185	COG1098	S1 RNA binding domain
BF39_RS23200	COG2208	phosphoserine phosphatase activity
BF39_RS23210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF39_RS23215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF39_RS23230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF39_RS23235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF39_RS23240	COG0512	Glutamine amidotransferase of anthranilate synthase
BF39_RS23245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF39_RS23250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF39_RS23255	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF39_RS23260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF39_RS23265	COG1396	sequence-specific DNA binding
BF39_RS23270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF39_RS23300	COG3880	PFAM UvrB UvrC protein
BF39_RS23310	COG0542	response to heat
BF39_RS23315	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF39_RS23325	COG4956	integral membrane protein (PIN domain superfamily)
BF39_RS23345	COG1045	serine acetyltransferase
BF39_RS23360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF39_RS23365	COG3688	RNA-binding protein containing a PIN domain
BF39_RS23380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF39_RS23385	COG0250	Participates in transcription elongation, termination and antitermination
BF39_RS23390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BF39_RS23410	COG2813	Specifically methylates the guanine in position
BF39_RS23420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF39_RS23425	COG1358	cellular component organization or biogenesis
BF39_RS23495	COG0255	Belongs to the universal ribosomal protein uL29 family
BF39_RS23555	COG0201	protein transport
BF39_RS23565	COG0024	Methionine aminopeptidase
BF39_RS23575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF39_RS23610	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF39_RS23635	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_RS23640	COG0489	protein tyrosine kinase activity
BF39_RS23650	COG2194	sulfuric ester hydrolase activity
BF39_RS23655	COG0726	polysaccharide deacetylase
BF39_RS23740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF39_RS23745	COG4856	YbbR-like protein
BF39_RS23760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF39_RS23765	COG0596	Alpha beta hydrolase
BF39_RS23785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF39_RS23790	COG0823	Involved in the tonB-independent uptake of proteins
BF39_RS23790	COG1506	peptidase
BF39_RS23790	COG4946	Tricorn protease homolog
BF39_RS23825	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS23830	COG2011	ABC-type metal ion transport system permease component
BF39_RS23835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF39_RS23840	COG1464	Belongs to the NlpA lipoprotein family
BF39_RS23845	COG0604	alcohol dehydrogenase
BF39_RS23855	COG0277	FAD linked oxidase domain protein
BF39_RS23860	COG2271	Major facilitator Superfamily
BF39_RS23870	COG2814	Major facilitator Superfamily
BF39_RS23885	COG0601	transmembrane transport
BF39_RS23890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_RS23895	COG0444	Belongs to the ABC transporter superfamily
BF39_RS23900	COG4608	Belongs to the ABC transporter superfamily
BF39_RS23905	COG4166	transmembrane transport
BF39_RS23915	COG2207	Transcriptional regulator
BF39_RS23930	COG4166	transmembrane transport
BF39_RS23935	COG4166	transmembrane transport
BF39_RS23940	COG0656	L-ascorbic acid biosynthetic process
BF39_RS23945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF39_RS23965	COG4149	molybdate abc transporter
BF39_RS23970	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF39_RS23975	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF39_RS23980	COG1910	domain protein
BF39_RS23995	COG0583	DNA-binding transcription factor activity
BF39_RS24000	COG0697	spore germination
BF39_RS24010	COG0204	Acyl-transferase
BF39_RS24020	COG1609	Transcriptional regulator
BF39_RS24030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS24045	COG0084	hydrolase, TatD family'
BF39_RS24050	COG5298	Protein conserved in bacteria
BF39_RS24075	COG0488	(ABC) transporter
BF39_RS24090	COG0747	negative chemotaxis
BF39_RS24095	COG0601	transmembrane transport
BF39_RS24100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_RS24105	COG0444	Belongs to the ABC transporter superfamily
BF39_RS24110	COG4608	Belongs to the ABC transporter superfamily
BF39_RS24150	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF39_RS24155	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF39_RS24165	COG2814	Major facilitator Superfamily
BF39_RS24180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF39_RS24190	COG4294	response to UV
BF39_RS24195	COG0705	Rhomboid family
BF39_RS24195	COG0457	Tetratricopeptide repeat
BF39_RS24205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF39_RS24210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF39_RS24215	COG0864	Transcriptional regulator
BF39_RS24220	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF39_RS24225	COG2183	response to ionizing radiation
BF39_RS24320	COG0802	atpase or kinase
BF39_RS24325	COG1214	PFAM Peptidase M22, glycoprotease
BF39_RS24330	COG0456	acetyltransferase
BF39_RS24340	COG0488	(ABC) transporter
BF39_RS24355	COG1266	CAAX protease self-immunity
BF39_RS24375	COG2252	PERMEase
BF39_RS24385	COG5002	protein histidine kinase activity
BF39_RS24415	COG2226	methyltransferase
BF39_RS24455	COG1968	undecaprenyl-diphosphatase activity
BF39_RS24470	COG2205	protein histidine kinase activity
BF39_RS24475	COG0745	RESPONSE REGULATOR receiver
BF39_RS24495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF39_RS24500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF39_RS24505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF39_RS24515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF39_RS24530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF39_RS24540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF39_RS24550	COG0151	Belongs to the GarS family
BF39_RS24575	COG0210	DNA helicase
BF39_RS24585	COG4851	CamS sex pheromone cAM373 precursor
BF39_RS24605	COG1335	isochorismatase
BF39_RS24610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BF39_RS24615	COG2011	ABC-type metal ion transport system permease component
BF39_RS24620	COG1464	Belongs to the NlpA lipoprotein family
BF39_RS24640	COG1846	Transcriptional regulator
BF39_RS24665	COG1597	lipid kinase activity
BF39_RS24670	COG0546	phosphoglycolate phosphatase activity
BF39_RS24675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF39_RS24685	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS24690	COG2076	Multidrug Resistance protein
BF39_RS24695	COG2309	aminopeptidase activity
BF39_RS24710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS24715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF39_RS24720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF39_RS24730	COG4807	Protein conserved in bacteria
BF39_RS24755	COG1757	Na H antiporter
BF39_RS24760	COG1473	amidohydrolase
BF39_RS24775	COG0450	alkyl hydroperoxide reductase
BF39_RS24795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS24800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS24805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS24825	COG0166	Belongs to the GPI family
BF39_RS24860	COG5002	protein histidine kinase activity
BF39_RS24880	COG3541	Predicted nucleotidyltransferase
BF39_RS24885	COG2814	Major facilitator Superfamily
BF39_RS24890	COG0723	plastoquinol--plastocyanin reductase activity
BF39_RS24890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_RS24900	COG0765	amino acid transport
BF39_RS24905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_RS24920	COG0840	transmembrane signaling receptor activity
BF39_RS24925	COG0840	transmembrane signaling receptor activity
BF39_RS24930	COG0366	Alpha amylase catalytic
BF39_RS24935	COG1263	PTS System
BF39_RS24935	COG2190	(PTS) system
BF39_RS24935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_RS24965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF39_RS24980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_RS24990	COG1116	anion transmembrane transporter activity
BF39_RS24995	COG0488	(ABC) transporter
BF39_RS25040	COG2270	Major facilitator Superfamily
BF39_RS25055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF39_RS25070	COG2310	stress, protein
BF39_RS25075	COG2310	stress, protein
BF39_RS25080	COG2310	stress, protein
BF39_RS25085	COG0861	Integral membrane protein TerC family
BF39_RS25095	COG3853	Toxic anion resistance protein (TelA)
BF39_RS25110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF39_RS25120	COG1295	ribonuclease BN
BF39_RS25125	COG2217	Heavy metal translocating P-type atpase
BF39_RS25130	COG0697	spore germination
BF39_RS25150	COG0586	Pfam SNARE associated Golgi protein
BF39_RS25165	COG3871	stress protein (general stress protein 26)
BF39_RS25170	COG0387	Pfam Sodium calcium exchanger
BF39_RS25180	COG0535	radical SAM domain protein
BF39_RS25205	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF39_RS25210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF39_RS25215	COG0582	viral genome integration into host DNA
BF39_RS25220	COG1396	sequence-specific DNA binding
BF39_RS25235	COG1396	sequence-specific DNA binding
BF39_RS25270	COG1484	DNA-dependent DNA replication
BF39_RS25365	COG0582	viral genome integration into host DNA
BF39_RS25370	COG0582	viral genome integration into host DNA
BF39_RS25495	COG0101	tRNA pseudouridine synthase activity
BF39_RS25505	COG3829	transcription factor binding
BF39_RS25515	COG0833	amino acid
BF39_RS25520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF39_RS25555	COG1263	PTS System
BF39_RS25555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_RS25560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF39_RS25575	COG0463	Glycosyl transferase, family 2
BF39_RS25590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF39_RS25590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF39_RS25610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF39_RS25630	COG1228	amidohydrolase
BF39_RS25635	COG1090	epimerase
BF39_RS25665	COG1988	membrane-bound metal-dependent
BF39_RS25670	COG1194	a g-specific adenine glycosylase
BF39_RS25695	COG1132	(ABC) transporter
BF39_RS25700	COG4129	membrane
BF39_RS25705	COG0070	glutamate synthase
BF39_RS25705	COG0069	glutamate synthase activity
BF39_RS25705	COG0067	glutamate synthase
BF39_RS25715	COG4555	ABC transporter
BF39_RS25735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF39_RS25740	COG0735	belongs to the Fur family
BF39_RS25855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF39_RS25860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF39_RS25870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF39_RS25880	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF39_RS25895	COG2766	serine protein kinase
BF39_RS25920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF39_RS25930	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF39_RS25935	COG2268	Band 7 protein
BF39_RS25945	COG3290	protein histidine kinase activity
BF39_RS25950	COG4565	transcriptional regulatory protein
BF39_RS25955	COG2851	Citrate transporter
BF39_RS25975	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF39_RS25980	COG3842	ATPase activity
BF39_RS25985	COG1175	transmembrane transport
BF39_RS25990	COG0395	ABC-type sugar transport system, permease component
BF39_RS26000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF39_RS26005	COG0745	RESPONSE REGULATOR receiver
BF39_RS26010	COG5002	protein histidine kinase activity
BF39_RS26020	COG4990	cell redox homeostasis
BF39_RS26030	COG3290	protein histidine kinase activity
BF39_RS26035	COG4565	transcriptional regulatory protein
BF39_RS26040	COG3493	citrate carrier protein
BF39_RS26045	COG0281	malic enzyme
BF39_RS26060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF39_RS26070	COG5002	protein histidine kinase activity
BF39_RS26075	COG0745	RESPONSE REGULATOR receiver
BF39_RS26085	COG0456	acetyltransferase
BF39_RS26085	COG0454	-acetyltransferase
BF39_RS26090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF39_RS26095	COG3383	formate dehydrogenase (NAD+) activity
BF39_RS26100	COG2427	Protein of unknown function (DUF1641)
BF39_RS26115	COG0531	amino acid
BF39_RS26120	COG0640	Transcriptional regulator
BF39_RS26125	COG2217	Heavy metal translocating P-type atpase
BF39_RS26130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF39_RS26140	COG3227	Zinc metalloprotease (Elastase)
BF39_RS26160	COG2720	vancomycin resistance protein
BF39_RS26165	COG1316	TRANSCRIPTIONal
BF39_RS26170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF39_RS26175	COG0346	lactoylglutathione lyase activity
BF39_RS26180	COG1253	flavin adenine dinucleotide binding
BF39_RS26185	COG1027	Aspartate ammonia-lyase
BF39_RS26190	COG1620	l-lactate permease
BF39_RS26205	COG3104	oligopeptide transport
BF39_RS26210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF39_RS26215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS26220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF39_RS26230	COG2226	methyltransferase
BF39_RS26235	COG0156	8-amino-7-oxononanoate synthase activity
BF39_RS26240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF39_RS26250	COG4548	von Willebrand factor, type A
BF39_RS26255	COG0714	Associated with various cellular activities
BF39_RS26260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_RS26280	COG0531	amino acid
BF39_RS26285	COG2188	Transcriptional regulator
BF39_RS26290	COG1263	PTS System
BF39_RS26290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_RS26295	COG0366	Alpha amylase catalytic
BF39_RS26310	COG0697	spore germination
BF39_RS26320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF39_RS26325	COG1115	amino acid carrier protein
BF39_RS26330	COG1126	abc transporter atp-binding protein
BF39_RS26335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_RS26340	COG0765	amino acid transport
BF39_RS26345	COG0765	amino acid transport
BF39_RS26350	COG0833	amino acid
BF39_RS26375	COG2378	regulation of single-species biofilm formation
BF39_RS26380	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF39_RS26385	COG5002	protein histidine kinase activity
BF39_RS26400	COG0659	secondary active sulfate transmembrane transporter activity
BF39_RS26415	COG0747	negative chemotaxis
BF39_RS26425	COG0601	transmembrane transport
BF39_RS26430	COG4608	Belongs to the ABC transporter superfamily
BF39_RS26440	COG2271	Major facilitator Superfamily
BF39_RS26445	COG1846	Transcriptional regulator
BF39_RS26450	COG0477	Major facilitator Superfamily
BF39_RS26455	COG0477	Major facilitator Superfamily
BF39_RS26460	COG1609	Transcriptional regulator
BF39_RS26465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF39_RS26480	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF39_RS26485	COG1879	ABC-type sugar transport system periplasmic component
BF39_RS26510	COG1063	alcohol dehydrogenase
BF39_RS26525	COG3568	Endonuclease Exonuclease Phosphatase
BF39_RS26550	COG1968	undecaprenyl-diphosphatase activity
BF39_RS26555	COG0840	transmembrane signaling receptor activity
BF39_RS26560	COG3584	3D domain protein
BF39_RS26560	COG1388	LysM domain
BF39_RS26565	COG1476	TRANSCRIPTIONal
BF39_RS26585	COG1114	Component of the transport system for branched-chain amino acids
BF39_RS26600	COG1113	amino acid transport
BF39_RS26605	COG2252	PERMEase
BF39_RS26630	COG0475	glutathione-regulated potassium exporter activity
BF39_RS26630	COG0569	domain protein
BF39_RS26645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF39_RS26650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF39_RS26655	COG0833	amino acid
BF39_RS26660	COG4990	cell redox homeostasis
BF39_RS26675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_RS26680	COG0697	spore germination
BF39_RS26685	COG0531	amino acid
BF39_RS26700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF39_RS26705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF39_RS26710	COG1918	ferrous iron import across plasma membrane
BF39_RS26710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF39_RS26715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF39_RS26720	COG0573	inorganic phosphate transmembrane transporter activity
BF39_RS26725	COG0581	inorganic phosphate transmembrane transporter activity
BF39_RS26735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF39_RS26870	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF39_RS26895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF39_RS26900	COG1116	anion transmembrane transporter activity
BF39_RS26905	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF39_RS26910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF39_RS26915	COG0352	thiamine-phosphate diphosphorylase activity
BF39_RS26920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF39_RS26925	COG2104	thiamine diphosphate biosynthetic process
BF39_RS26935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF39_RS26940	COG0351	phosphomethylpyrimidine kinase
BF39_RS26980	COG2205	protein histidine kinase activity
BF39_RS26985	COG2814	Major facilitator Superfamily
BF39_RS26990	COG1846	Transcriptional regulator
BF39_RS27005	COG2252	PERMEase
BF39_RS27010	COG1028	Short-chain dehydrogenase reductase Sdr
BF39_RS27025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF39_RS27030	COG1621	beta-fructofuranosidase activity
BF39_RS27035	COG1263	PTS System
BF39_RS27035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_RS27040	COG1609	Transcriptional regulator
BF39_RS27050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF39_RS27055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BF39_RS27095	COG0778	Nitroreductase
BF39_RS27100	COG2719	SpoVR family
BF39_RS27125	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF39_RS27130	COG1937	Protein conserved in bacteria
BF39_RS27135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_RS27135	COG0425	Belongs to the sulfur carrier protein TusA family
BF39_RS27140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF39_RS27140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_RS27145	COG0425	Belongs to the sulfur carrier protein TusA family
BF39_RS27150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF39_RS27160	COG2210	Belongs to the sulfur carrier protein TusA family
BF39_RS27165	COG0730	response to heat
BF39_RS27175	COG1316	TRANSCRIPTIONal
BF39_RS27180	COG0604	alcohol dehydrogenase
BF39_RS27185	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF39_RS27200	COG3711	transcriptional antiterminator
BF39_RS27200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF39_RS27205	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF39_RS27210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF39_RS27230	COG3584	3D domain protein
BF39_RS27230	COG1388	LysM domain
BF39_RS27235	COG0577	efflux transmembrane transporter activity
BF39_RS27240	COG1136	(ABC) transporter
BF39_RS27250	COG5522	Integral membrane protein (intg_mem_TP0381)
BF39_RS27265	COG1114	Component of the transport system for branched-chain amino acids
BF39_RS27270	COG3546	catalase activity
BF39_RS27305	COG0586	Pfam SNARE associated Golgi protein
BF39_RS27340	COG0531	amino acid
BF39_RS27345	COG0475	glutathione-regulated potassium exporter activity
BF39_RS27355	COG1737	Transcriptional regulator
BF39_RS27365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF39_RS27365	COG1263	PTS System
BF39_RS27375	COG2259	Doxx family
BF39_RS27390	COG0697	spore germination
BF39_RS27395	COG1522	sequence-specific DNA binding
BF39_RS27410	COG2076	Multidrug Resistance protein
BF39_RS27415	COG1309	transcriptional regulator
BF39_RS27420	COG2814	Major facilitator Superfamily
BF39_RS27425	COG1733	regulation of RNA biosynthetic process
BF39_RS27435	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF39_RS27440	COG4533	DNA binding
BF39_RS27445	COG2211	Major facilitator Superfamily
BF39_RS27455	COG0693	protein deglycase activity
BF39_RS27460	COG0693	protein deglycase activity
BF39_RS27460	COG0753	catalase activity
BF39_RS27470	COG0531	amino acid
BF39_RS27475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF39_RS27485	COG1012	belongs to the aldehyde dehydrogenase family
BF39_RS27495	COG1132	(ABC) transporter
BF39_RS27505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_RS27510	COG0765	amino acid transport
BF39_RS27515	COG1126	abc transporter atp-binding protein
BF39_RS27530	COG0189	ligase activity
BF39_RS27560	COG0028	Belongs to the TPP enzyme family
BF39_RS27565	COG3527	Alpha-acetolactate decarboxylase
BF39_RS27580	COG0561	phosphatase activity
BF39_RS27595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF39_RS27610	COG0659	secondary active sulfate transmembrane transporter activity
BF39_RS27630	COG0653	protein targeting
BF39_RS27635	COG2244	polysaccharide biosynthetic process
BF39_RS27645	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF39_RS27650	COG4196	transglutaminase domain protein
BF39_RS27665	COG1696	Membrane protein involved in D-alanine export
BF39_RS27680	COG1024	Enoyl-CoA hydratase
BF39_RS27700	COG1363	Peptidase, m42
BF39_RS27720	COG3938	Belongs to the proline racemase family
BF39_RS27760	COG0601	transmembrane transport
BF39_RS27765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_RS27775	COG4608	Belongs to the ABC transporter superfamily
BF39_RS27805	COG0477	Major facilitator Superfamily
BF39_RS27810	COG3290	protein histidine kinase activity
BF39_RS27815	COG4565	transcriptional regulatory protein
BF39_RS27820	COG3181	Tripartite tricarboxylate transporter family receptor
BF39_RS27850	COG0789	Transcriptional regulator
BF39_RS27850	COG4978	Transcriptional regulator
BF39_RS27865	COG0305	Participates in initiation and elongation during chromosome replication
BF39_RS27905	COG0477	Major facilitator Superfamily
BF39_RS27955	COG3320	Male sterility
BF39_RS27955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF39_RS27960	COG1309	transcriptional regulator
BF39_RS27980	COG1183	phosphatidylcholine synthase activity
BF39_RS28000	COG2376	Dihydroxyacetone kinase
BF39_RS28015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BF39_RS28020	COG1959	2 iron, 2 sulfur cluster binding
BF39_RS28095	COG3237	CsbD-like
BF39_RS28120	COG1191	sigma factor activity
BF39_RS28130	COG2208	phosphoserine phosphatase activity
BF39_RS28135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF39_RS28140	COG0784	Response regulator, receiver
BF39_RS28140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF39_RS28140	COG2198	Histidine kinase
BF39_RS28140	COG2205	protein histidine kinase activity
BF39_RS28200	COG0420	3'-5' exonuclease activity
BF39_RS28205	COG4717	serine-type aminopeptidase activity
BF39_RS28225	COG1309	transcriptional regulator
BF39_RS28230	COG2814	Major facilitator Superfamily
BF39_RS28235	COG0346	lactoylglutathione lyase activity
BF39_RS28240	COG0346	lactoylglutathione lyase activity
BF39_RS28245	COG0457	Tetratricopeptide repeat
BF39_RS28250	COG2267	carboxylic ester hydrolase activity
BF39_RS28270	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF39_RS28275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF39_RS28285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF39_RS28325	COG0477	Major facilitator Superfamily
BF39_RS28330	COG0477	Major facilitator Superfamily
BF39_RS28340	COG3973	AAA domain
BF39_RS28345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF39_RS28370	COG4980	gas vesicle protein
BF39_RS28375	COG0537	adenosine 5'-monophosphoramidase activity
BF39_RS28380	COG1131	(ABC) transporter
BF39_RS28385	COG4473	ABC transporter
BF39_RS28395	COG1309	transcriptional regulator
BF39_RS28405	COG3402	PFAM membrane-flanked domain
BF39_RS28415	COG3428	Bacterial PH domain
BF39_RS28460	COG3402	PFAM membrane-flanked domain
BF39_RS28465	COG3428	Bacterial PH domain
BF39_RS28470	COG2329	Antibiotic biosynthesis monooxygenase
BF39_RS28475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF39_RS28480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF39_RS28485	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF39_RS28490	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF39_RS28525	COG1309	transcriptional regulator
BF39_RS28530	COG1511	domain protein
BF39_RS28555	COG1609	Transcriptional regulator
BF39_RS28565	COG1234	tRNA 3'-trailer cleavage
BF39_RS28570	COG0095	Lipoate-protein ligase
BF39_RS28580	COG0318	PFAM AMP-dependent synthetase and ligase
BF39_RS28610	COG3209	COG3209 Rhs family protein
BF39_RS28655	COG1408	metallophosphoesterase
BF39_RS28660	COG1078	dGTPase activity
BF39_RS28670	COG1595	DNA-templated transcription, initiation
BF39_RS28675	COG3708	Transcriptional regulator
BF39_RS28675	COG2207	Transcriptional regulator
BF39_RS28690	COG2205	protein histidine kinase activity
BF39_RS28695	COG0745	RESPONSE REGULATOR receiver
BF39_RS28720	COG0501	Belongs to the peptidase M48B family
BF39_RS28725	COG0840	transmembrane signaling receptor activity
BF39_RS28730	COG0697	spore germination
BF39_RS28750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF39_RS28755	COG2224	Isocitrate lyase
BF39_RS28780	COG4903	ComK protein
BF39_RS28785	COG0398	Pfam SNARE associated Golgi protein
BF39_RS28800	COG1074	ATP-dependent DNA helicase activity
BF39_RS28845	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF39_RS28870	COG0367	asparagine synthase
BF39_RS28875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BF39_RS28880	COG0753	catalase activity
BF39_RS28885	COG0004	ammonium transporteR
BF39_RS28910	COG2996	Protein conserved in bacteria
BF39_RS28920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF39_RS28930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF39_RS28945	COG0561	phosphatase activity
BF39_RS28960	COG0542	response to heat
BF39_RS28970	COG2267	carboxylic ester hydrolase activity
BF39_RS28985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF39_RS28990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF39_RS28995	COG5504	Zn-dependent protease
BF39_RS29005	COG0180	Tryptophanyl-tRNA synthetase
BF39_RS29015	COG4166	transmembrane transport
BF39_RS29020	COG0601	transmembrane transport
BF39_RS29025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF39_RS29030	COG0444	Belongs to the ABC transporter superfamily
BF39_RS29035	COG4608	Belongs to the ABC transporter superfamily
BF39_RS29040	COG0534	Mate efflux family protein
BF39_RS29045	COG4166	transmembrane transport
BF39_RS29065	COG0861	Integral membrane protein TerC family
BF39_RS29070	COG4862	establishment of competence for transformation
BF39_RS29075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF39_RS29085	COG1164	Oligoendopeptidase f
BF39_RS29095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF39_RS29100	COG2346	COG2346, Truncated hemoglobins
BF39_RS29105	COG4116	CYTH
BF39_RS29115	COG2357	RelA SpoT domain protein
BF39_RS29125	COG0564	pseudouridine synthase activity
BF39_RS29140	COG0772	Belongs to the SEDS family
BF39_RS29145	COG1216	Glycosyl transferase, family 2
BF39_RS29145	COG0463	Glycosyl transferase, family 2
BF39_RS29165	COG0457	Tetratricopeptide repeat
BF39_RS29165	COG0463	Glycosyl transferase, family 2
BF39_RS29185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF39_RS29200	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF39_RS29245	COG2153	protein acetylation
BF39_RS29255	COG2382	esterase
BF39_RS29270	COG5492	domain, Protein
BF39_RS29275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF39_RS29290	COG0512	Glutamine amidotransferase of anthranilate synthase
BF39_RS29290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF39_RS29350	COG2376	Dihydroxyacetone kinase