locus-tag	class	description
H9401_RS00010	COG0592	DNA-directed DNA polymerase activity
H9401_RS00015	COG2501	S4 domain
H9401_RS00025	COG0187	DNA topoisomerase II activity
H9401_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9401_RS00065	COG0517	IMP dehydrogenase activity
H9401_RS00065	COG0516	GMP reductase activity
H9401_RS00070	COG1686	Belongs to the peptidase S11 family
H9401_RS00100	COG1428	Deoxynucleoside kinase
H9401_RS00105	COG1428	Deoxynucleoside kinase
H9401_RS00110	COG1335	isochorismatase
H9401_RS00120	COG0590	tRNA wobble adenosine to inosine editing
H9401_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9401_RS00180	COG1982	Orn Lys Arg decarboxylase major
H9401_RS00190	COG0470	DNA polymerase III
H9401_RS00195	COG1774	PSP1 C-terminal conserved region
H9401_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9401_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9401_RS00220	COG2002	toxin-antitoxin pair type II binding
H9401_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9401_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9401_RS00230	COG0084	hydrolase, TatD family'
H9401_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H9401_RS00250	COG4466	Protein conserved in bacteria
H9401_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9401_RS00270	COG0251	oxidation-reduction process
H9401_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9401_RS00305	COG2002	toxin-antitoxin pair type II binding
H9401_RS00310	COG2244	polysaccharide biosynthetic process
H9401_RS00315	COG3956	TIGRFAM MazG family protein
H9401_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9401_RS00340	COG1098	S1 RNA binding domain
H9401_RS00355	COG2208	phosphoserine phosphatase activity
H9401_RS00360	COG0037	tRNA processing
H9401_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9401_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9401_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9401_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9401_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
H9401_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9401_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9401_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9401_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9401_RS00420	COG1396	sequence-specific DNA binding
H9401_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9401_RS00455	COG3880	PFAM UvrB UvrC protein
H9401_RS00465	COG0542	response to heat
H9401_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9401_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
H9401_RS00500	COG1045	serine acetyltransferase
H9401_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9401_RS00520	COG3688	RNA-binding protein containing a PIN domain
H9401_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9401_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
H9401_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9401_RS00565	COG2813	Specifically methylates the guanine in position
H9401_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9401_RS00580	COG1358	cellular component organization or biogenesis
H9401_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
H9401_RS00710	COG0201	protein transport
H9401_RS00720	COG0024	Methionine aminopeptidase
H9401_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9401_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9401_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9401_RS00795	COG0489	protein tyrosine kinase activity
H9401_RS00805	COG2194	sulfuric ester hydrolase activity
H9401_RS00810	COG0726	polysaccharide deacetylase
H9401_RS00895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H9401_RS00900	COG4856	YbbR-like protein
H9401_RS00915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9401_RS00920	COG0596	Alpha beta hydrolase
H9401_RS00940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9401_RS00945	COG0823	Involved in the tonB-independent uptake of proteins
H9401_RS00945	COG4946	Tricorn protease homolog
H9401_RS00945	COG1506	peptidase
H9401_RS00980	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS00985	COG2011	ABC-type metal ion transport system permease component
H9401_RS00995	COG1464	Belongs to the NlpA lipoprotein family
H9401_RS01000	COG0604	alcohol dehydrogenase
H9401_RS01010	COG0277	FAD linked oxidase domain protein
H9401_RS01015	COG2271	Major facilitator Superfamily
H9401_RS01025	COG2814	Major facilitator Superfamily
H9401_RS01040	COG0601	transmembrane transport
H9401_RS01045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9401_RS01050	COG0444	Belongs to the ABC transporter superfamily
H9401_RS01055	COG4608	Belongs to the ABC transporter superfamily
H9401_RS01060	COG4166	transmembrane transport
H9401_RS01070	COG2207	Transcriptional regulator
H9401_RS01085	COG4166	transmembrane transport
H9401_RS01090	COG4166	transmembrane transport
H9401_RS01095	COG0656	L-ascorbic acid biosynthetic process
H9401_RS01100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9401_RS01120	COG4149	molybdate abc transporter
H9401_RS01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9401_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9401_RS01135	COG1910	domain protein
H9401_RS01150	COG0583	DNA-binding transcription factor activity
H9401_RS01155	COG0697	spore germination
H9401_RS01165	COG0204	Acyl-transferase
H9401_RS01175	COG1609	Transcriptional regulator
H9401_RS01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS01200	COG0084	hydrolase, TatD family'
H9401_RS01205	COG5298	Protein conserved in bacteria
H9401_RS01230	COG0488	(ABC) transporter
H9401_RS01245	COG0747	negative chemotaxis
H9401_RS01250	COG0601	transmembrane transport
H9401_RS01255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9401_RS01260	COG0444	Belongs to the ABC transporter superfamily
H9401_RS01265	COG4608	Belongs to the ABC transporter superfamily
H9401_RS01305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
H9401_RS01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9401_RS01335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9401_RS01345	COG4294	response to UV
H9401_RS01350	COG0457	Tetratricopeptide repeat
H9401_RS01350	COG0705	Rhomboid family
H9401_RS01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H9401_RS01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9401_RS01370	COG0864	Transcriptional regulator
H9401_RS01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9401_RS01380	COG2183	response to ionizing radiation
H9401_RS01475	COG0802	atpase or kinase
H9401_RS01480	COG1214	PFAM Peptidase M22, glycoprotease
H9401_RS01485	COG0456	acetyltransferase
H9401_RS01495	COG0488	(ABC) transporter
H9401_RS01510	COG1266	CAAX protease self-immunity
H9401_RS01530	COG2252	PERMEase
H9401_RS01540	COG5002	protein histidine kinase activity
H9401_RS01570	COG2226	methyltransferase
H9401_RS01610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9401_RS01615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9401_RS01620	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9401_RS01630	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9401_RS01645	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9401_RS01655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9401_RS01665	COG0151	Belongs to the GarS family
H9401_RS01690	COG0210	DNA helicase
H9401_RS01700	COG4851	CamS sex pheromone cAM373 precursor
H9401_RS01720	COG1335	isochorismatase
H9401_RS01725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9401_RS01730	COG2011	ABC-type metal ion transport system permease component
H9401_RS01735	COG1464	Belongs to the NlpA lipoprotein family
H9401_RS01755	COG1846	Transcriptional regulator
H9401_RS01780	COG1597	lipid kinase activity
H9401_RS01785	COG0546	phosphoglycolate phosphatase activity
H9401_RS01790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9401_RS01800	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS01805	COG2076	Multidrug Resistance protein
H9401_RS01810	COG2309	aminopeptidase activity
H9401_RS01825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS01830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9401_RS01835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9401_RS01845	COG4807	Protein conserved in bacteria
H9401_RS01870	COG1757	Na H antiporter
H9401_RS01875	COG1473	amidohydrolase
H9401_RS01890	COG0450	alkyl hydroperoxide reductase
H9401_RS01910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS01915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS01920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS01940	COG0166	Belongs to the GPI family
H9401_RS01975	COG5002	protein histidine kinase activity
H9401_RS01995	COG3541	Predicted nucleotidyltransferase
H9401_RS02000	COG2814	Major facilitator Superfamily
H9401_RS02005	COG0723	plastoquinol--plastocyanin reductase activity
H9401_RS02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9401_RS02015	COG0765	amino acid transport
H9401_RS02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9401_RS02035	COG0840	transmembrane signaling receptor activity
H9401_RS02040	COG0840	transmembrane signaling receptor activity
H9401_RS02045	COG0366	Alpha amylase catalytic
H9401_RS02050	COG2190	(PTS) system
H9401_RS02050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9401_RS02050	COG1263	PTS System
H9401_RS02080	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H9401_RS02095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9401_RS02105	COG1116	anion transmembrane transporter activity
H9401_RS02110	COG0488	(ABC) transporter
H9401_RS02155	COG2270	Major facilitator Superfamily
H9401_RS02170	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9401_RS02185	COG2310	stress, protein
H9401_RS02190	COG2310	stress, protein
H9401_RS02195	COG2310	stress, protein
H9401_RS02200	COG0861	Integral membrane protein TerC family
H9401_RS02210	COG3853	Toxic anion resistance protein (TelA)
H9401_RS02225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9401_RS02235	COG1295	ribonuclease BN
H9401_RS02240	COG2217	Heavy metal translocating P-type atpase
H9401_RS02245	COG0697	spore germination
H9401_RS02265	COG0586	Pfam SNARE associated Golgi protein
H9401_RS02280	COG3871	stress protein (general stress protein 26)
H9401_RS02285	COG0387	Pfam Sodium calcium exchanger
H9401_RS02295	COG0535	radical SAM domain protein
H9401_RS02320	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9401_RS02325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9401_RS02330	COG0582	viral genome integration into host DNA
H9401_RS02335	COG1396	sequence-specific DNA binding
H9401_RS02350	COG1396	sequence-specific DNA binding
H9401_RS02385	COG1484	DNA-dependent DNA replication
H9401_RS02480	COG0582	viral genome integration into host DNA
H9401_RS02485	COG0582	viral genome integration into host DNA
H9401_RS02610	COG0101	tRNA pseudouridine synthase activity
H9401_RS02620	COG3829	transcription factor binding
H9401_RS02630	COG0833	amino acid
H9401_RS02635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9401_RS02670	COG1263	PTS System
H9401_RS02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9401_RS02675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9401_RS02690	COG0463	Glycosyl transferase, family 2
H9401_RS02705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9401_RS02705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9401_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9401_RS02745	COG1228	amidohydrolase
H9401_RS02750	COG1090	epimerase
H9401_RS02780	COG1988	membrane-bound metal-dependent
H9401_RS02785	COG1194	a g-specific adenine glycosylase
H9401_RS02810	COG1132	(ABC) transporter
H9401_RS02815	COG4129	membrane
H9401_RS02820	COG0070	glutamate synthase
H9401_RS02820	COG0069	glutamate synthase activity
H9401_RS02820	COG0067	glutamate synthase
H9401_RS02830	COG4555	ABC transporter
H9401_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9401_RS02855	COG0735	belongs to the Fur family
H9401_RS02970	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H9401_RS02975	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9401_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9401_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9401_RS03010	COG2766	serine protein kinase
H9401_RS03035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9401_RS03045	COG1585	Membrane protein implicated in regulation of membrane protease activity
H9401_RS03050	COG2268	Band 7 protein
H9401_RS03060	COG3290	protein histidine kinase activity
H9401_RS03065	COG4565	transcriptional regulatory protein
H9401_RS03070	COG2851	Citrate transporter
H9401_RS03090	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H9401_RS03095	COG3842	ATPase activity
H9401_RS03100	COG1175	transmembrane transport
H9401_RS03115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9401_RS03120	COG0745	RESPONSE REGULATOR receiver
H9401_RS03125	COG5002	protein histidine kinase activity
H9401_RS03135	COG4990	cell redox homeostasis
H9401_RS03145	COG3290	protein histidine kinase activity
H9401_RS03150	COG4565	transcriptional regulatory protein
H9401_RS03155	COG3493	citrate carrier protein
H9401_RS03160	COG0281	malic enzyme
H9401_RS03175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS03185	COG5002	protein histidine kinase activity
H9401_RS03190	COG0745	RESPONSE REGULATOR receiver
H9401_RS03200	COG0454	-acetyltransferase
H9401_RS03200	COG0456	acetyltransferase
H9401_RS03205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9401_RS03210	COG3383	formate dehydrogenase (NAD+) activity
H9401_RS03215	COG2427	Protein of unknown function (DUF1641)
H9401_RS03230	COG0531	amino acid
H9401_RS03235	COG0640	Transcriptional regulator
H9401_RS03240	COG2217	Heavy metal translocating P-type atpase
H9401_RS03245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9401_RS03255	COG3227	Zinc metalloprotease (Elastase)
H9401_RS03275	COG2720	vancomycin resistance protein
H9401_RS03280	COG1316	TRANSCRIPTIONal
H9401_RS03285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS03290	COG0346	lactoylglutathione lyase activity
H9401_RS03295	COG1253	flavin adenine dinucleotide binding
H9401_RS03300	COG1027	Aspartate ammonia-lyase
H9401_RS03305	COG1620	l-lactate permease
H9401_RS03320	COG3104	oligopeptide transport
H9401_RS03325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS03330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS03335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS03345	COG2226	methyltransferase
H9401_RS03350	COG0156	8-amino-7-oxononanoate synthase activity
H9401_RS03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9401_RS03365	COG4548	von Willebrand factor, type A
H9401_RS03370	COG0714	Associated with various cellular activities
H9401_RS03375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9401_RS03395	COG0531	amino acid
H9401_RS03400	COG2188	Transcriptional regulator
H9401_RS03405	COG1263	PTS System
H9401_RS03405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9401_RS03410	COG0366	Alpha amylase catalytic
H9401_RS03425	COG0697	spore germination
H9401_RS03435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9401_RS03440	COG1115	amino acid carrier protein
H9401_RS03445	COG1126	abc transporter atp-binding protein
H9401_RS03450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9401_RS03455	COG0765	amino acid transport
H9401_RS03460	COG0765	amino acid transport
H9401_RS03465	COG0833	amino acid
H9401_RS03490	COG2378	regulation of single-species biofilm formation
H9401_RS03495	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9401_RS03500	COG5002	protein histidine kinase activity
H9401_RS03515	COG0659	secondary active sulfate transmembrane transporter activity
H9401_RS03530	COG0747	negative chemotaxis
H9401_RS03540	COG0601	transmembrane transport
H9401_RS03545	COG4608	Belongs to the ABC transporter superfamily
H9401_RS03555	COG2271	Major facilitator Superfamily
H9401_RS03560	COG1846	Transcriptional regulator
H9401_RS03565	COG0477	Major facilitator Superfamily
H9401_RS03570	COG0477	Major facilitator Superfamily
H9401_RS03575	COG1609	Transcriptional regulator
H9401_RS03580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9401_RS03595	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9401_RS03600	COG1879	ABC-type sugar transport system periplasmic component
H9401_RS03625	COG1063	alcohol dehydrogenase
H9401_RS03640	COG3568	Endonuclease Exonuclease Phosphatase
H9401_RS03665	COG1968	undecaprenyl-diphosphatase activity
H9401_RS03670	COG0840	transmembrane signaling receptor activity
H9401_RS03675	COG3584	3D domain protein
H9401_RS03675	COG1388	LysM domain
H9401_RS03680	COG1476	TRANSCRIPTIONal
H9401_RS03695	COG3104	oligopeptide transport
H9401_RS03700	COG1114	Component of the transport system for branched-chain amino acids
H9401_RS03715	COG1113	amino acid transport
H9401_RS03720	COG2252	PERMEase
H9401_RS03745	COG0475	glutathione-regulated potassium exporter activity
H9401_RS03745	COG0569	domain protein
H9401_RS03760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9401_RS03765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9401_RS03770	COG0833	amino acid
H9401_RS03775	COG4990	cell redox homeostasis
H9401_RS03790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9401_RS03795	COG0697	spore germination
H9401_RS03800	COG0531	amino acid
H9401_RS03815	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9401_RS03820	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9401_RS03825	COG1918	ferrous iron import across plasma membrane
H9401_RS03825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9401_RS03830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9401_RS03835	COG0573	inorganic phosphate transmembrane transporter activity
H9401_RS03840	COG0581	inorganic phosphate transmembrane transporter activity
H9401_RS03850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9401_RS03970	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H9401_RS03995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9401_RS04000	COG1116	anion transmembrane transporter activity
H9401_RS04005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9401_RS04010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9401_RS04015	COG0352	thiamine-phosphate diphosphorylase activity
H9401_RS04020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9401_RS04025	COG2104	thiamine diphosphate biosynthetic process
H9401_RS04035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9401_RS04040	COG0351	phosphomethylpyrimidine kinase
H9401_RS04085	COG2205	protein histidine kinase activity
H9401_RS04090	COG2814	Major facilitator Superfamily
H9401_RS04095	COG1846	Transcriptional regulator
H9401_RS04110	COG2252	PERMEase
H9401_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS04130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9401_RS04135	COG1621	beta-fructofuranosidase activity
H9401_RS04140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9401_RS04140	COG1263	PTS System
H9401_RS04145	COG1609	Transcriptional regulator
H9401_RS04155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9401_RS04160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H9401_RS04200	COG0778	Nitroreductase
H9401_RS04205	COG2719	SpoVR family
H9401_RS04230	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9401_RS04235	COG1937	Protein conserved in bacteria
H9401_RS04240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9401_RS04240	COG0425	Belongs to the sulfur carrier protein TusA family
H9401_RS04245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9401_RS04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS04250	COG0425	Belongs to the sulfur carrier protein TusA family
H9401_RS04255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9401_RS04265	COG2210	Belongs to the sulfur carrier protein TusA family
H9401_RS04270	COG0730	response to heat
H9401_RS04280	COG1316	TRANSCRIPTIONal
H9401_RS04285	COG0604	alcohol dehydrogenase
H9401_RS04290	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9401_RS04305	COG3711	transcriptional antiterminator
H9401_RS04305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9401_RS04310	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9401_RS04315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9401_RS04335	COG3584	3D domain protein
H9401_RS04335	COG1388	LysM domain
H9401_RS04340	COG0577	efflux transmembrane transporter activity
H9401_RS04345	COG1136	(ABC) transporter
H9401_RS04355	COG5522	Integral membrane protein (intg_mem_TP0381)
H9401_RS04370	COG1114	Component of the transport system for branched-chain amino acids
H9401_RS04375	COG3546	catalase activity
H9401_RS04410	COG0586	Pfam SNARE associated Golgi protein
H9401_RS04445	COG0531	amino acid
H9401_RS04450	COG0475	glutathione-regulated potassium exporter activity
H9401_RS04460	COG1737	Transcriptional regulator
H9401_RS04470	COG1263	PTS System
H9401_RS04470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9401_RS04480	COG2259	Doxx family
H9401_RS04495	COG0697	spore germination
H9401_RS04500	COG1522	sequence-specific DNA binding
H9401_RS04515	COG2076	Multidrug Resistance protein
H9401_RS04520	COG1309	transcriptional regulator
H9401_RS04525	COG2814	Major facilitator Superfamily
H9401_RS04530	COG1733	regulation of RNA biosynthetic process
H9401_RS04540	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9401_RS04545	COG4533	DNA binding
H9401_RS04550	COG2211	Major facilitator Superfamily
H9401_RS04560	COG0693	protein deglycase activity
H9401_RS04565	COG0753	catalase activity
H9401_RS04565	COG0693	protein deglycase activity
H9401_RS04575	COG0531	amino acid
H9401_RS04580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9401_RS04590	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS04600	COG1132	(ABC) transporter
H9401_RS04610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9401_RS04615	COG0765	amino acid transport
H9401_RS04620	COG1126	abc transporter atp-binding protein
H9401_RS04635	COG0189	ligase activity
H9401_RS04665	COG0028	Belongs to the TPP enzyme family
H9401_RS04670	COG3527	Alpha-acetolactate decarboxylase
H9401_RS04685	COG0561	phosphatase activity
H9401_RS04700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9401_RS04715	COG0659	secondary active sulfate transmembrane transporter activity
H9401_RS04735	COG0653	protein targeting
H9401_RS04740	COG2244	polysaccharide biosynthetic process
H9401_RS04750	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9401_RS04755	COG4196	transglutaminase domain protein
H9401_RS04770	COG1696	Membrane protein involved in D-alanine export
H9401_RS04785	COG1024	Enoyl-CoA hydratase
H9401_RS04805	COG1363	Peptidase, m42
H9401_RS04825	COG3938	Belongs to the proline racemase family
H9401_RS04865	COG0601	transmembrane transport
H9401_RS04870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9401_RS04880	COG4608	Belongs to the ABC transporter superfamily
H9401_RS04910	COG0477	Major facilitator Superfamily
H9401_RS04915	COG3290	protein histidine kinase activity
H9401_RS04920	COG4565	transcriptional regulatory protein
H9401_RS04925	COG3181	Tripartite tricarboxylate transporter family receptor
H9401_RS04955	COG4978	Transcriptional regulator
H9401_RS04955	COG0789	Transcriptional regulator
H9401_RS04970	COG0305	Participates in initiation and elongation during chromosome replication
H9401_RS05010	COG0477	Major facilitator Superfamily
H9401_RS05060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9401_RS05060	COG3320	Male sterility
H9401_RS05065	COG1309	transcriptional regulator
H9401_RS05085	COG1183	phosphatidylcholine synthase activity
H9401_RS05105	COG2376	Dihydroxyacetone kinase
H9401_RS05120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9401_RS05125	COG1959	2 iron, 2 sulfur cluster binding
H9401_RS05150	COG3437	response regulator, receiver
H9401_RS05150	COG2770	Histidine kinase
H9401_RS05200	COG3237	CsbD-like
H9401_RS05225	COG1191	sigma factor activity
H9401_RS05235	COG2208	phosphoserine phosphatase activity
H9401_RS05240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9401_RS05245	COG0784	Response regulator, receiver
H9401_RS05245	COG2198	Histidine kinase
H9401_RS05245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9401_RS05245	COG2205	protein histidine kinase activity
H9401_RS05305	COG0420	3'-5' exonuclease activity
H9401_RS05310	COG4717	serine-type aminopeptidase activity
H9401_RS05330	COG1309	transcriptional regulator
H9401_RS05335	COG2814	Major facilitator Superfamily
H9401_RS05340	COG0346	lactoylglutathione lyase activity
H9401_RS05345	COG0346	lactoylglutathione lyase activity
H9401_RS05350	COG0457	Tetratricopeptide repeat
H9401_RS05355	COG2267	carboxylic ester hydrolase activity
H9401_RS05375	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H9401_RS05380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9401_RS05390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H9401_RS05430	COG0477	Major facilitator Superfamily
H9401_RS05435	COG0477	Major facilitator Superfamily
H9401_RS05445	COG3973	AAA domain
H9401_RS05450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9401_RS05475	COG4980	gas vesicle protein
H9401_RS05480	COG0537	adenosine 5'-monophosphoramidase activity
H9401_RS05485	COG1131	(ABC) transporter
H9401_RS05490	COG4473	ABC transporter
H9401_RS05500	COG1309	transcriptional regulator
H9401_RS05510	COG3402	PFAM membrane-flanked domain
H9401_RS05520	COG3428	Bacterial PH domain
H9401_RS05565	COG3402	PFAM membrane-flanked domain
H9401_RS05570	COG3428	Bacterial PH domain
H9401_RS05575	COG2329	Antibiotic biosynthesis monooxygenase
H9401_RS05580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9401_RS05585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9401_RS05590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9401_RS05595	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H9401_RS05630	COG1309	transcriptional regulator
H9401_RS05635	COG1511	domain protein
H9401_RS05660	COG1609	Transcriptional regulator
H9401_RS05670	COG1234	tRNA 3'-trailer cleavage
H9401_RS05675	COG0095	Lipoate-protein ligase
H9401_RS05685	COG0318	PFAM AMP-dependent synthetase and ligase
H9401_RS05715	COG3209	COG3209 Rhs family protein
H9401_RS05760	COG1408	metallophosphoesterase
H9401_RS05765	COG1078	dGTPase activity
H9401_RS05775	COG1595	DNA-templated transcription, initiation
H9401_RS05780	COG3708	Transcriptional regulator
H9401_RS05780	COG2207	Transcriptional regulator
H9401_RS05795	COG2205	protein histidine kinase activity
H9401_RS05800	COG0745	RESPONSE REGULATOR receiver
H9401_RS05825	COG0501	Belongs to the peptidase M48B family
H9401_RS05830	COG0840	transmembrane signaling receptor activity
H9401_RS05835	COG0697	spore germination
H9401_RS05855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H9401_RS05860	COG2224	Isocitrate lyase
H9401_RS05885	COG4903	ComK protein
H9401_RS05890	COG0398	Pfam SNARE associated Golgi protein
H9401_RS05900	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H9401_RS05905	COG1074	ATP-dependent DNA helicase activity
H9401_RS05950	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9401_RS05975	COG0367	asparagine synthase
H9401_RS05980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9401_RS05985	COG0753	catalase activity
H9401_RS05990	COG0004	ammonium transporteR
H9401_RS06015	COG2996	Protein conserved in bacteria
H9401_RS06025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9401_RS06035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS06050	COG0561	phosphatase activity
H9401_RS06065	COG0542	response to heat
H9401_RS06075	COG2267	carboxylic ester hydrolase activity
H9401_RS06090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9401_RS06095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9401_RS06100	COG5504	Zn-dependent protease
H9401_RS06110	COG0180	Tryptophanyl-tRNA synthetase
H9401_RS06120	COG4166	transmembrane transport
H9401_RS06125	COG0601	transmembrane transport
H9401_RS06130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9401_RS06135	COG0444	Belongs to the ABC transporter superfamily
H9401_RS06140	COG4608	Belongs to the ABC transporter superfamily
H9401_RS06145	COG0534	Mate efflux family protein
H9401_RS06150	COG4166	transmembrane transport
H9401_RS06170	COG0861	Integral membrane protein TerC family
H9401_RS06175	COG4862	establishment of competence for transformation
H9401_RS06180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9401_RS06190	COG1164	Oligoendopeptidase f
H9401_RS06200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9401_RS06205	COG2346	COG2346, Truncated hemoglobins
H9401_RS06210	COG4116	CYTH
H9401_RS06220	COG2357	RelA SpoT domain protein
H9401_RS06230	COG0564	pseudouridine synthase activity
H9401_RS06245	COG0772	Belongs to the SEDS family
H9401_RS06250	COG0463	Glycosyl transferase, family 2
H9401_RS06250	COG1216	Glycosyl transferase, family 2
H9401_RS06270	COG0457	Tetratricopeptide repeat
H9401_RS06270	COG0463	Glycosyl transferase, family 2
H9401_RS06290	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H9401_RS06305	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9401_RS06350	COG2153	protein acetylation
H9401_RS06360	COG2382	esterase
H9401_RS06375	COG5492	domain, Protein
H9401_RS06380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9401_RS06395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9401_RS06395	COG0512	Glutamine amidotransferase of anthranilate synthase
H9401_RS06430	COG1620	l-lactate permease
H9401_RS06435	COG5634	Uncharacterized conserved protein (DUF2278)
H9401_RS06485	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9401_RS06495	COG1476	TRANSCRIPTIONal
H9401_RS06555	COG2226	methyltransferase
H9401_RS06565	COG1686	Belongs to the peptidase S11 family
H9401_RS06570	COG0681	Belongs to the peptidase S26 family
H9401_RS06605	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS06610	COG3842	ATPase activity
H9401_RS06615	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9401_RS06620	COG1177	transmembrane transport
H9401_RS06625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H9401_RS06635	COG2409	Drug exporters of the RND superfamily
H9401_RS06655	COG2340	Cysteine-rich secretory protein family
H9401_RS06660	COG0247	lactate metabolic process
H9401_RS06665	COG0277	FAD linked oxidase domain protein
H9401_RS06670	COG3835	regulator
H9401_RS06680	COG0745	RESPONSE REGULATOR receiver
H9401_RS06685	COG5002	protein histidine kinase activity
H9401_RS06690	COG2186	Transcriptional regulator
H9401_RS06710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9401_RS06720	COG2116	formate transmembrane transporter activity
H9401_RS06725	COG0861	Integral membrane protein TerC family
H9401_RS06730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9401_RS06740	COG2030	dehydratase
H9401_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS06765	COG3243	poly(R)-hydroxyalkanoic acid synthase
H9401_RS06770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9401_RS06775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9401_RS06790	COG1840	ABC-type Fe3 transport system, periplasmic component
H9401_RS06820	COG1349	DNA-binding transcription factor activity
H9401_RS06845	COG2861	carbohydrate metabolic process
H9401_RS06855	COG3852	Histidine kinase
H9401_RS06860	COG1846	Transcriptional regulator
H9401_RS06870	COG2318	DinB family
H9401_RS06880	COG5002	protein histidine kinase activity
H9401_RS06890	COG0720	synthase
H9401_RS06905	COG4873	Protein conserved in bacteria
H9401_RS06940	COG1780	Probably involved in ribonucleotide reductase function
H9401_RS06955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9401_RS06960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9401_RS06965	COG1725	Transcriptional regulator
H9401_RS06970	COG1131	(ABC) transporter
H9401_RS06980	COG1131	(ABC) transporter
H9401_RS06985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H9401_RS07000	COG1522	sequence-specific DNA binding
H9401_RS07010	COG1335	isochorismatase
H9401_RS07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9401_RS07025	COG2070	2-Nitropropane dioxygenase
H9401_RS07030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H9401_RS07040	COG1696	Membrane protein involved in D-alanine export
H9401_RS07065	COG0716	FMN binding
H9401_RS07080	COG3173	Aminoglycoside phosphotransferase
H9401_RS07100	COG0534	Mate efflux family protein
H9401_RS07105	COG1968	undecaprenyl-diphosphatase activity
H9401_RS07120	COG1846	Transcriptional regulator
H9401_RS07130	COG1301	dicarboxylic acid transport
H9401_RS07135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9401_RS07140	COG4709	membrane
H9401_RS07145	COG3874	Sporulation protein YtfJ
H9401_RS07175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9401_RS07180	COG0028	Belongs to the TPP enzyme family
H9401_RS07185	COG0440	acetolactate synthase activity
H9401_RS07190	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9401_RS07200	COG0473	3-isopropylmalate dehydrogenase activity
H9401_RS07225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9401_RS07260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9401_RS07275	COG1183	phosphatidylcholine synthase activity
H9401_RS07280	COG1368	sulfuric ester hydrolase activity
H9401_RS07290	COG0019	diaminopimelate decarboxylase activity
H9401_RS07310	COG0529	Catalyzes the synthesis of activated sulfate
H9401_RS07315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9401_RS07335	COG1648	precorrin-2 dehydrogenase activity
H9401_RS07345	COG0733	neurotransmitter:sodium symporter activity
H9401_RS07365	COG1757	Na H antiporter
H9401_RS07380	COG4758	membrane
H9401_RS07385	COG4585	Histidine kinase
H9401_RS07390	COG2197	response regulator
H9401_RS07400	COG1114	Component of the transport system for branched-chain amino acids
H9401_RS07410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9401_RS07435	COG1017	nitric oxide dioxygenase activity
H9401_RS07435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9401_RS07455	COG0730	response to heat
H9401_RS07460	COG0306	phosphate transporter
H9401_RS07465	COG1392	Phosphate transport regulator
H9401_RS07470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9401_RS07485	COG3852	Histidine kinase
H9401_RS07490	COG1801	Protein of unknown function DUF72
H9401_RS07500	COG0582	viral genome integration into host DNA
H9401_RS07505	COG5002	protein histidine kinase activity
H9401_RS07525	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H9401_RS07525	COG0392	lysyltransferase activity
H9401_RS07540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9401_RS07545	COG1686	Belongs to the peptidase S11 family
H9401_RS07550	COG2715	membrane protein required for spore maturation
H9401_RS07555	COG0700	Nucleoside recognition
H9401_RS07560	COG1187	pseudouridine synthase activity
H9401_RS07570	COG1333	cytochrome c biogenesis protein
H9401_RS07575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9401_RS07580	COG0745	RESPONSE REGULATOR receiver
H9401_RS07585	COG5002	protein histidine kinase activity
H9401_RS07590	COG2096	Adenosyltransferase
H9401_RS07605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9401_RS07610	COG1141	Ferredoxin
H9401_RS07615	COG4955	Helix-turn-helix domain
H9401_RS07620	COG0514	ATP-dependent DNA helicase (RecQ)
H9401_RS07625	COG1266	CAAX protease self-immunity
H9401_RS07645	COG4862	establishment of competence for transformation
H9401_RS07650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9401_RS07670	COG0492	ferredoxin-NADP+ reductase activity
H9401_RS07675	COG0252	asparaginase activity
H9401_RS07745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9401_RS07760	COG0142	geranyltranstransferase activity
H9401_RS07770	COG0142	geranyltranstransferase activity
H9401_RS07790	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9401_RS07795	COG0457	Tetratricopeptide repeat
H9401_RS07815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9401_RS07825	COG4347	Protein of unknown function (DUF1405)
H9401_RS07840	COG2738	Putative neutral zinc metallopeptidase
H9401_RS07850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS07855	COG1694	Mazg nucleotide pyrophosphohydrolase
H9401_RS07870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9401_RS07875	COG0438	transferase activity, transferring glycosyl groups
H9401_RS07915	COG1199	ATP-dependent helicase activity
H9401_RS07915	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9401_RS07935	COG3935	DnaD domain protein
H9401_RS07940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9401_RS07950	COG4499	WXG100 protein secretion system (Wss), protein YukC
H9401_RS07950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9401_RS08000	COG0116	Belongs to the methyltransferase superfamily
H9401_RS08010	COG1199	ATP-dependent helicase activity
H9401_RS08015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9401_RS08025	COG3173	Aminoglycoside phosphotransferase
H9401_RS08030	COG0024	Methionine aminopeptidase
H9401_RS08040	COG2233	PERMEase
H9401_RS08045	COG2311	Membrane
H9401_RS08050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9401_RS08060	COG0456	acetyltransferase
H9401_RS08085	COG0754	glutathionylspermidine amidase activity
H9401_RS08100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9401_RS08125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9401_RS08140	COG1215	transferase activity, transferring glycosyl groups
H9401_RS08145	COG0438	transferase activity, transferring glycosyl groups
H9401_RS08160	COG0454	-acetyltransferase
H9401_RS08180	COG0328	RNA-DNA hybrid ribonuclease activity
H9401_RS08220	COG1280	lysine exporter protein (LysE YggA)
H9401_RS08235	COG3162	membrane
H9401_RS08240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9401_RS08245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9401_RS08255	COG0475	glutathione-regulated potassium exporter activity
H9401_RS08260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9401_RS08265	COG0789	Transcriptional regulator
H9401_RS08265	COG4978	Transcriptional regulator
H9401_RS08275	COG2323	membrane
H9401_RS08280	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H9401_RS08335	COG1923	regulation of RNA biosynthetic process
H9401_RS08345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9401_RS08350	COG1360	Flagellar Motor Protein
H9401_RS08355	COG2201	protein-glutamate methylesterase activity
H9401_RS08365	COG1776	CheC inhibitor of MCP methylation
H9401_RS08365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9401_RS08380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9401_RS08400	COG1256	bacterial-type flagellum assembly
H9401_RS08405	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9401_RS08430	COG1815	bacterial-type flagellum-dependent cell motility
H9401_RS08435	COG1558	bacterial-type flagellum-dependent cell motility
H9401_RS08445	COG1766	The M ring may be actively involved in energy transduction
H9401_RS08455	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9401_RS08465	COG1157	protein secretion by the type III secretion system
H9401_RS08505	COG0784	Response regulator, receiver
H9401_RS08505	COG0835	chemotaxis
H9401_RS08515	COG0463	Glycosyl transferase, family 2
H9401_RS08545	COG0457	Tetratricopeptide repeat
H9401_RS08545	COG0463	Glycosyl transferase, family 2
H9401_RS08570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9401_RS08575	COG0741	lytic transglycosylase activity
H9401_RS08590	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9401_RS08590	COG1776	CheC inhibitor of MCP methylation
H9401_RS08600	COG1338	Plays a role in the flagellum-specific transport system
H9401_RS08605	COG1987	bacterial-type flagellum assembly
H9401_RS08615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9401_RS08620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9401_RS08625	COG1419	protein localization to endoplasmic reticulum
H9401_RS08630	COG4786	Flagellar basal body rod
H9401_RS08635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9401_RS08660	COG1309	transcriptional regulator
H9401_RS08680	COG2329	Antibiotic biosynthesis monooxygenase
H9401_RS08705	COG0583	DNA-binding transcription factor activity
H9401_RS08710	COG3842	ATPase activity
H9401_RS08715	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9401_RS08725	COG1234	tRNA 3'-trailer cleavage
H9401_RS08750	COG1686	Belongs to the peptidase S11 family
H9401_RS08760	COG0406	alpha-ribazole phosphatase activity
H9401_RS08790	COG0367	asparagine synthase
H9401_RS08820	COG1802	Transcriptional regulator
H9401_RS08830	COG0523	cobalamin synthesis protein
H9401_RS08835	COG0701	Predicted permease
H9401_RS08845	COG0438	transferase activity, transferring glycosyl groups
H9401_RS08845	COG1216	Glycosyl transferase, family 2
H9401_RS08850	COG1757	Na H antiporter
H9401_RS08855	COG0114	fumarate hydratase activity
H9401_RS08885	COG3340	Belongs to the peptidase S51 family
H9401_RS08905	COG0785	Cytochrome C biogenesis protein
H9401_RS08940	COG2733	membrane
H9401_RS08975	COG1131	(ABC) transporter
H9401_RS08990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9401_RS08995	COG0528	UMP kinase activity
H9401_RS09005	COG1027	Aspartate ammonia-lyase
H9401_RS09010	COG0281	malic enzyme
H9401_RS09015	COG4191	Histidine kinase
H9401_RS09020	COG0784	Response regulator, receiver
H9401_RS09025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9401_RS09085	COG1051	belongs to the nudix hydrolase family
H9401_RS09090	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9401_RS09100	COG2814	Major facilitator Superfamily
H9401_RS09115	COG1966	Carbon starvation protein
H9401_RS09130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9401_RS09140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9401_RS09150	COG4166	transmembrane transport
H9401_RS09155	COG2223	nitrite transmembrane transporter activity
H9401_RS09160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9401_RS09175	COG2244	polysaccharide biosynthetic process
H9401_RS09180	COG0733	neurotransmitter:sodium symporter activity
H9401_RS09190	COG5566	PFAM Mor transcription activator
H9401_RS09195	COG2323	membrane
H9401_RS09210	COG2084	Dehydrogenase
H9401_RS09225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9401_RS09235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9401_RS09240	COG0028	Belongs to the TPP enzyme family
H9401_RS09245	COG0440	acetolactate synthase activity
H9401_RS09250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9401_RS09260	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9401_RS09285	COG2814	Major facilitator Superfamily
H9401_RS09290	COG3384	dioxygenase
H9401_RS09300	COG3279	Response regulator of the LytR AlgR family
H9401_RS09305	COG0427	acetyl-CoA hydrolase
H9401_RS09325	COG1073	alpha beta
H9401_RS09330	COG4166	transmembrane transport
H9401_RS09355	COG0535	radical SAM domain protein
H9401_RS09360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS09380	COG1914	H( )-stimulated, divalent metal cation uptake system
H9401_RS09395	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9401_RS09430	COG2390	Transcriptional regulator
H9401_RS09440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS09445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9401_RS09460	COG4224	UPF0291 protein
H9401_RS09480	COG0006	proline dipeptidase activity
H9401_RS09485	COG2132	Multicopper oxidase
H9401_RS09500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9401_RS09515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9401_RS09530	COG2372	response to copper ion
H9401_RS09530	COG1276	copper resistance
H9401_RS09535	COG4549	nuclear export factor GLE1
H9401_RS09545	COG0697	spore germination
H9401_RS09550	COG0583	DNA-binding transcription factor activity
H9401_RS09555	COG1959	2 iron, 2 sulfur cluster binding
H9401_RS09560	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9401_RS09565	COG0778	Nitroreductase
H9401_RS09580	COG0628	permease
H9401_RS09590	COG1231	oxidoreductase activity
H9401_RS09595	COG0523	cobalamin synthesis protein
H9401_RS09610	COG0318	PFAM AMP-dependent synthetase and ligase
H9401_RS09615	COG2030	dehydratase
H9401_RS09620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9401_RS09630	COG0411	ABC transporter
H9401_RS09650	COG0583	DNA-binding transcription factor activity
H9401_RS09660	COG1942	4-Oxalocrotonate Tautomerase
H9401_RS09670	COG1846	Transcriptional regulator
H9401_RS09680	COG1271	oxidase subunit
H9401_RS09685	COG1294	oxidase, subunit
H9401_RS09690	COG4988	ABC transporter
H9401_RS09695	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H9401_RS09715	COG1686	Belongs to the peptidase S11 family
H9401_RS09730	COG1388	LysM domain
H9401_RS09730	COG0791	NLP P60 protein
H9401_RS09740	COG1132	(ABC) transporter
H9401_RS09745	COG1132	(ABC) transporter
H9401_RS09750	COG0745	RESPONSE REGULATOR receiver
H9401_RS09755	COG5002	protein histidine kinase activity
H9401_RS09765	COG0300	oxidoreductase activity
H9401_RS09800	COG0460	homoserine dehydrogenase
H9401_RS09825	COG1316	TRANSCRIPTIONal
H9401_RS09835	COG0745	RESPONSE REGULATOR receiver
H9401_RS09855	COG1285	pathogenesis
H9401_RS09860	COG1247	-acetyltransferase
H9401_RS09880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9401_RS09890	COG1082	Xylose isomerase domain protein TIM barrel
H9401_RS09905	COG1279	arginine transmembrane transporter activity
H9401_RS09915	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9401_RS09955	COG2002	toxin-antitoxin pair type II binding
H9401_RS09960	COG1404	Belongs to the peptidase S8 family
H9401_RS09965	COG0640	Transcriptional regulator
H9401_RS09970	COG0667	Aldo Keto reductase
H9401_RS09975	COG2814	Major facilitator Superfamily
H9401_RS10000	COG0840	transmembrane signaling receptor activity
H9401_RS10020	COG3949	Membrane
H9401_RS10025	COG0783	Belongs to the Dps family
H9401_RS10040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9401_RS10050	COG1231	oxidoreductase activity
H9401_RS10060	COG4989	oxidoreductase activity
H9401_RS10065	COG0523	cobalamin synthesis protein
H9401_RS10070	COG0456	acetyltransferase
H9401_RS10135	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9401_RS10135	COG3443	Belongs to the bacterial solute-binding protein 9 family
H9401_RS10145	COG0702	epimerase
H9401_RS10155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9401_RS10165	COG4166	transmembrane transport
H9401_RS10180	COG0406	alpha-ribazole phosphatase activity
H9401_RS10190	COG5337	Spore coat protein CotH
H9401_RS10195	COG1051	belongs to the nudix hydrolase family
H9401_RS10200	COG0586	Pfam SNARE associated Golgi protein
H9401_RS10205	COG2244	polysaccharide biosynthetic process
H9401_RS10215	COG0701	Predicted permease
H9401_RS10220	COG3689	TIGRFAM TIGR03943 family protein
H9401_RS10225	COG1607	acyl-coa hydrolase
H9401_RS10230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9401_RS10245	COG0702	epimerase
H9401_RS10250	COG2839	Protein conserved in bacteria
H9401_RS10255	COG1253	flavin adenine dinucleotide binding
H9401_RS10270	COG1114	Component of the transport system for branched-chain amino acids
H9401_RS10275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9401_RS10295	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9401_RS10305	COG1876	peptidase activity
H9401_RS10315	COG0154	amidase activity
H9401_RS10320	COG2211	Major facilitator Superfamily
H9401_RS10340	COG0561	phosphatase activity
H9401_RS10350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9401_RS10355	COG4106	trans-aconitate 2-methyltransferase activity
H9401_RS10370	COG1819	glycosyl
H9401_RS10375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS10380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS10405	COG0456	acetyltransferase
H9401_RS10455	COG3874	Sporulation protein YtfJ
H9401_RS10480	COG2226	methyltransferase
H9401_RS10500	COG1082	Xylose isomerase domain protein TIM barrel
H9401_RS10505	COG0346	lactoylglutathione lyase activity
H9401_RS10515	COG0604	alcohol dehydrogenase
H9401_RS10520	COG1595	DNA-templated transcription, initiation
H9401_RS10545	COG0386	Belongs to the glutathione peroxidase family
H9401_RS10550	COG1305	Transglutaminase-like
H9401_RS10555	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H9401_RS10560	COG0714	Associated with various cellular activities
H9401_RS10575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H9401_RS10580	COG1140	nitrate reductase beta subunit
H9401_RS10585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H9401_RS10590	COG2181	nitrate reductase activity
H9401_RS10610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9401_RS10615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9401_RS10620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9401_RS10625	COG0303	'Molybdopterin
H9401_RS10630	COG0314	molybdopterin synthase activity
H9401_RS10640	COG2223	nitrite transmembrane transporter activity
H9401_RS10655	COG1648	precorrin-2 dehydrogenase activity
H9401_RS10665	COG1587	Uroporphyrinogen-III synthase
H9401_RS10665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9401_RS10670	COG2146	nitrite reductase [NAD(P)H] activity
H9401_RS10675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9401_RS10680	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
H9401_RS10715	COG2359	stage V sporulation protein S
H9401_RS10730	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9401_RS10745	COG1418	mRNA catabolic process
H9401_RS10750	COG0488	(ABC) transporter
H9401_RS10765	COG0629	single-stranded DNA binding
H9401_RS10780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9401_RS10785	COG1413	lyase activity
H9401_RS10800	COG2521	methyltransferase
H9401_RS10800	COG2136	Putative SAM-dependent methyltransferase
H9401_RS10805	COG0018	arginyl-trna synthetase
H9401_RS10830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9401_RS10845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9401_RS10850	COG0017	Asparaginyl-tRNA synthetase
H9401_RS10870	COG1674	ftsk spoiiie
H9401_RS10965	COG1929	Belongs to the glycerate kinase type-1 family
H9401_RS10970	COG0471	metal ion transport
H9401_RS10975	COG0745	RESPONSE REGULATOR receiver
H9401_RS10980	COG3850	Histidine kinase
H9401_RS10980	COG5002	protein histidine kinase activity
H9401_RS10995	COG0733	neurotransmitter:sodium symporter activity
H9401_RS11020	COG2610	gluconate transmembrane transporter activity
H9401_RS11025	COG1454	alcohol dehydrogenase
H9401_RS11030	COG1794	racemase activity, acting on amino acids and derivatives
H9401_RS11040	COG0456	acetyltransferase
H9401_RS11055	COG1131	(ABC) transporter
H9401_RS11060	COG4473	ABC transporter
H9401_RS11070	COG0546	phosphoglycolate phosphatase activity
H9401_RS11090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9401_RS11105	COG0768	penicillin binding
H9401_RS11110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9401_RS11115	COG0204	Acyl-transferase
H9401_RS11120	COG1272	protein, Hemolysin III
H9401_RS11130	COG0805	protein transport
H9401_RS11140	COG1307	EDD domain protein, DegV family
H9401_RS11145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9401_RS11150	COG1999	signal sequence binding
H9401_RS11155	COG0071	Belongs to the small heat shock protein (HSP20) family
H9401_RS11160	COG0367	asparagine synthase
H9401_RS11175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS11180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9401_RS11215	COG0668	transmembrane transport
H9401_RS11220	COG4585	Histidine kinase
H9401_RS11220	COG2203	Gaf domain
H9401_RS11225	COG2197	response regulator
H9401_RS11235	COG1737	Transcriptional regulator
H9401_RS11240	COG1064	alcohol dehydrogenase
H9401_RS11270	COG1070	Carbohydrate kinase
H9401_RS11275	COG1070	Carbohydrate kinase
H9401_RS11305	COG1125	glycine betaine transport
H9401_RS11305	COG0517	IMP dehydrogenase activity
H9401_RS11310	COG1174	glycine betaine transport
H9401_RS11345	COG1253	flavin adenine dinucleotide binding
H9401_RS11350	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS11355	COG5506	Protein of unknown function (DUF1694)
H9401_RS11370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9401_RS11375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H9401_RS11380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H9401_RS11385	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9401_RS11390	COG0456	acetyltransferase
H9401_RS11395	COG3829	transcription factor binding
H9401_RS11400	COG1509	lysine 2,3-aminomutase activity
H9401_RS11440	COG4326	sporulation control protein
H9401_RS11445	COG0671	phosphoesterase, PA-phosphatase related
H9401_RS11450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9401_RS11455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9401_RS11485	COG1787	Restriction endonuclease
H9401_RS11485	COG1715	Restriction endonuclease
H9401_RS11575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9401_RS11615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9401_RS11615	COG4499	WXG100 protein secretion system (Wss), protein YukC
H9401_RS11620	COG2814	Major facilitator Superfamily
H9401_RS11625	COG4841	protein insertion into membrane
H9401_RS11630	COG0372	Belongs to the citrate synthase family
H9401_RS11635	COG2079	MmgE PrpD family protein
H9401_RS11640	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H9401_RS11645	COG1960	acyl-CoA dehydrogenase activity
H9401_RS11650	COG2084	Dehydrogenase
H9401_RS11660	COG1280	lysine exporter protein (LysE YggA)
H9401_RS11665	COG1024	Enoyl-CoA hydratase
H9401_RS11680	COG0420	3'-5' exonuclease activity
H9401_RS11685	COG0419	ATPase involved in DNA repair
H9401_RS11715	COG2223	nitrite transmembrane transporter activity
H9401_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS11725	COG1169	isochorismate synthase
H9401_RS11730	COG1021	2,3-dihydroxybenzoate-AMP ligase
H9401_RS11735	COG3433	isochorismatase activity
H9401_RS11735	COG1535	isochorismatase
H9401_RS11740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9401_RS11745	COG3251	PFAM MbtH domain protein
H9401_RS11750	COG2814	Major facilitator Superfamily
H9401_RS11765	COG0776	regulation of translation
H9401_RS11775	COG2318	DinB family
H9401_RS11785	COG1115	amino acid carrier protein
H9401_RS11805	COG2329	Antibiotic biosynthesis monooxygenase
H9401_RS11810	COG1187	pseudouridine synthase activity
H9401_RS11815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9401_RS11830	COG0596	Alpha beta hydrolase
H9401_RS11835	COG2814	Major facilitator Superfamily
H9401_RS11855	COG2226	methyltransferase
H9401_RS11900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS11935	COG1247	-acetyltransferase
H9401_RS11965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H9401_RS11975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS11985	COG1278	Cold shock
H9401_RS12000	COG0010	Belongs to the arginase family
H9401_RS12005	COG0561	phosphatase activity
H9401_RS12050	COG0583	DNA-binding transcription factor activity
H9401_RS12055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9401_RS12070	COG0583	DNA-binding transcription factor activity
H9401_RS12075	COG2258	MOSC domain
H9401_RS12090	COG1132	(ABC) transporter
H9401_RS12095	COG1132	(ABC) transporter
H9401_RS12115	COG1396	sequence-specific DNA binding
H9401_RS12140	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
H9401_RS12145	COG1595	DNA-templated transcription, initiation
H9401_RS12170	COG1649	PFAM Uncharacterised BCR, COG1649
H9401_RS12195	COG2971	BadF BadG BcrA BcrD
H9401_RS12200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9401_RS12205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9401_RS12225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS12255	COG1309	transcriptional regulator
H9401_RS12270	COG1136	(ABC) transporter
H9401_RS12270	COG0577	efflux transmembrane transporter activity
H9401_RS12275	COG0500	methyltransferase
H9401_RS12275	COG3615	Tellurite resistance protein tehB
H9401_RS12285	COG2226	methyltransferase
H9401_RS12290	COG3961	Belongs to the TPP enzyme family
H9401_RS12295	COG1846	Transcriptional regulator
H9401_RS12335	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9401_RS12350	COG1595	DNA-templated transcription, initiation
H9401_RS12360	COG0768	penicillin binding
H9401_RS12370	COG2367	Beta-lactamase
H9401_RS12375	COG0671	phosphoesterase, PA-phosphatase related
H9401_RS12380	COG1609	Transcriptional regulator
H9401_RS12385	COG2814	Major facilitator Superfamily
H9401_RS12390	COG0673	inositol 2-dehydrogenase activity
H9401_RS12400	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS12415	COG0191	fructose-bisphosphate aldolase activity
H9401_RS12420	COG3718	enzyme involved in inositol metabolism
H9401_RS12450	COG0457	Tetratricopeptide repeat
H9401_RS12455	COG1476	TRANSCRIPTIONal
H9401_RS12470	COG1876	peptidase activity
H9401_RS12490	COG1309	transcriptional regulator
H9401_RS12495	COG0488	(ABC) transporter
H9401_RS12510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS12520	COG1252	NADH dehydrogenase
H9401_RS12525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9401_RS12540	COG1131	(ABC) transporter
H9401_RS12550	COG1309	transcriptional regulator
H9401_RS12565	COG1960	acyl-CoA dehydrogenase activity
H9401_RS12570	COG0439	Biotin carboxylase
H9401_RS12575	COG0511	ligase activity, forming carbon-carbon bonds
H9401_RS12580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9401_RS12585	COG1024	Enoyl-CoA hydratase
H9401_RS12590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9401_RS12595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9401_RS12605	COG1247	-acetyltransferase
H9401_RS12610	COG0572	uridine kinase
H9401_RS12620	COG2318	DinB family
H9401_RS12625	COG1686	Belongs to the peptidase S11 family
H9401_RS12650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9401_RS12690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9401_RS12715	COG2814	Major facilitator Superfamily
H9401_RS12735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9401_RS12755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS12770	COG1063	alcohol dehydrogenase
H9401_RS12785	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9401_RS12790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9401_RS12805	COG3773	Cell wall hydrolase
H9401_RS12815	COG0745	RESPONSE REGULATOR receiver
H9401_RS12830	COG0488	(ABC) transporter
H9401_RS12845	COG1136	(ABC) transporter
H9401_RS12870	COG0460	homoserine dehydrogenase
H9401_RS12875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS12885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9401_RS12960	COG2124	cytochrome p450
H9401_RS12995	COG0561	phosphatase activity
H9401_RS13005	COG5002	protein histidine kinase activity
H9401_RS13010	COG0768	penicillin binding
H9401_RS13015	COG1819	glycosyl
H9401_RS13020	COG1794	racemase activity, acting on amino acids and derivatives
H9401_RS13030	COG1122	ATPase activity
H9401_RS13050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9401_RS13055	COG0604	alcohol dehydrogenase
H9401_RS13060	COG0768	penicillin binding
H9401_RS13070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9401_RS13105	COG0693	protein deglycase activity
H9401_RS13135	COG2814	Major facilitator Superfamily
H9401_RS13150	COG0584	glycerophosphoryl diester phosphodiesterase
H9401_RS13170	COG0697	spore germination
H9401_RS13195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9401_RS13205	COG2223	nitrite transmembrane transporter activity
H9401_RS13220	COG2816	NAD+ diphosphatase activity
H9401_RS13225	COG0592	DNA-directed DNA polymerase activity
H9401_RS13230	COG1051	belongs to the nudix hydrolase family
H9401_RS13265	COG3878	Protein conserved in bacteria
H9401_RS13295	COG4667	esterase of the alpha-beta hydrolase superfamily
H9401_RS13320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9401_RS13335	COG0322	excinuclease ABC activity
H9401_RS13375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9401_RS13400	COG1011	Hydrolase
H9401_RS13420	COG0076	glutamate decarboxylase activity
H9401_RS13435	COG1523	belongs to the glycosyl hydrolase 13 family
H9401_RS13440	COG3227	Zinc metalloprotease (Elastase)
H9401_RS13460	COG0201	protein transport
H9401_RS13470	COG0697	spore germination
H9401_RS13475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS13505	COG4129	membrane
H9401_RS13510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS13525	COG2959	enzyme of heme biosynthesis
H9401_RS13545	COG3483	tryptophan 2,3-dioxygenase activity
H9401_RS13550	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H9401_RS13555	COG3844	kynureninase activity
H9401_RS13560	COG1309	transcriptional regulator
H9401_RS13590	COG3284	Transcriptional regulator
H9401_RS13610	COG1349	DNA-binding transcription factor activity
H9401_RS13630	COG1959	2 iron, 2 sulfur cluster binding
H9401_RS13645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9401_RS13655	COG0022	dehydrogenase e1 component
H9401_RS13660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9401_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS13675	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9401_RS13675	COG0456	acetyltransferase
H9401_RS13710	COG4176	ABC-type proline glycine betaine transport system permease component
H9401_RS13715	COG4175	Glycine betaine
H9401_RS13715	COG0517	IMP dehydrogenase activity
H9401_RS13740	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9401_RS13745	COG2153	protein acetylation
H9401_RS13750	COG3397	chitin binding
H9401_RS13765	COG2205	protein histidine kinase activity
H9401_RS13795	COG0658	competence protein
H9401_RS13795	COG2333	competence protein COMEC
H9401_RS13845	COG3973	AAA domain
H9401_RS13860	COG2105	PFAM AIG2 family protein
H9401_RS13865	COG0514	ATP-dependent DNA helicase (RecQ)
H9401_RS13895	COG4637	Psort location Cytoplasmic, score
H9401_RS13920	COG3397	chitin binding
H9401_RS13930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9401_RS13935	COG1115	amino acid carrier protein
H9401_RS13940	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS13945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9401_RS13955	COG3938	Belongs to the proline racemase family
H9401_RS13960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9401_RS14000	COG0586	Pfam SNARE associated Golgi protein
H9401_RS14015	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H9401_RS14020	COG0519	Catalyzes the synthesis of GMP from XMP
H9401_RS14025	COG4166	transmembrane transport
H9401_RS14035	COG4948	Mandelate Racemase Muconate Lactonizing
H9401_RS14075	COG2936	dipeptidyl-peptidase activity
H9401_RS14080	COG5002	protein histidine kinase activity
H9401_RS14125	COG1307	EDD domain protein, DegV family
H9401_RS14145	COG2814	Major facilitator Superfamily
H9401_RS14155	COG1664	Polymer-forming cytoskeletal
H9401_RS14160	COG0789	Transcriptional regulator
H9401_RS14165	COG4533	DNA binding
H9401_RS14170	COG0477	Major facilitator Superfamily
H9401_RS14170	COG2814	Major facilitator Superfamily
H9401_RS14190	COG2261	transglycosylase associated protein
H9401_RS14240	COG0436	Aminotransferase
H9401_RS14245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9401_RS14250	COG5146	pantothenate kinase activity
H9401_RS14270	COG1131	(ABC) transporter
H9401_RS14320	COG0628	permease
H9401_RS14335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9401_RS14340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9401_RS14345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9401_RS14350	COG1116	anion transmembrane transporter activity
H9401_RS14370	COG2816	NAD+ diphosphatase activity
H9401_RS14390	COG2746	aminoglycoside 3-N-acetyltransferase activity
H9401_RS14415	COG0697	spore germination
H9401_RS14420	COG2318	DinB family
H9401_RS14440	COG4912	Dna alkylation repair
H9401_RS14460	COG0861	Integral membrane protein TerC family
H9401_RS14465	COG1368	sulfuric ester hydrolase activity
H9401_RS14470	COG0488	(ABC) transporter
H9401_RS14480	COG2409	Drug exporters of the RND superfamily
H9401_RS14480	COG1033	growth of symbiont in host cell
H9401_RS14485	COG1033	growth of symbiont in host cell
H9401_RS14485	COG2409	Drug exporters of the RND superfamily
H9401_RS14490	COG2409	Drug exporters of the RND superfamily
H9401_RS14490	COG1033	growth of symbiont in host cell
H9401_RS14495	COG1309	transcriptional regulator
H9401_RS14510	COG0287	Prephenate dehydrogenase
H9401_RS14515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9401_RS14520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9401_RS14525	COG1605	Chorismate mutase
H9401_RS14525	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9401_RS14560	COG1388	LysM domain
H9401_RS14560	COG3584	3D domain protein
H9401_RS14570	COG1595	DNA-templated transcription, initiation
H9401_RS14595	COG1879	ABC-type sugar transport system periplasmic component
H9401_RS14605	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9401_RS14615	COG2390	Transcriptional regulator
H9401_RS14650	COG2329	Antibiotic biosynthesis monooxygenase
H9401_RS14670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS14680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9401_RS14685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9401_RS14690	COG4187	Peptidase family M20/M25/M40
H9401_RS14695	COG1414	Transcriptional regulator
H9401_RS14700	COG0833	amino acid
H9401_RS14705	COG1690	Belongs to the RtcB family
H9401_RS14710	COG3239	Fatty acid desaturase
H9401_RS14715	COG1785	Belongs to the alkaline phosphatase family
H9401_RS14725	COG3655	Transcriptional regulator
H9401_RS14740	COG4377	Putative membrane peptidase family (DUF2324)
H9401_RS14750	COG3279	Response regulator of the LytR AlgR family
H9401_RS14760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS14765	COG0346	lactoylglutathione lyase activity
H9401_RS14785	COG0714	Associated with various cellular activities
H9401_RS14835	COG0463	Glycosyl transferase, family 2
H9401_RS14845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9401_RS14850	COG0753	catalase activity
H9401_RS14860	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H9401_RS14885	COG0714	Associated with various cellular activities
H9401_RS14895	COG0778	Nitroreductase
H9401_RS14900	COG1846	Transcriptional regulator
H9401_RS14935	COG1725	Transcriptional regulator
H9401_RS14945	COG1136	(ABC) transporter
H9401_RS14945	COG0577	efflux transmembrane transporter activity
H9401_RS14970	COG2207	Transcriptional regulator
H9401_RS14975	COG0456	acetyltransferase
H9401_RS14995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS15015	COG0642	Histidine kinase
H9401_RS15020	COG0745	RESPONSE REGULATOR receiver
H9401_RS15025	COG0596	Alpha beta hydrolase
H9401_RS15055	COG0730	response to heat
H9401_RS15065	COG0833	amino acid
H9401_RS15075	COG4335	DNA alkylation repair
H9401_RS15115	COG0768	penicillin binding
H9401_RS15125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9401_RS15160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9401_RS15165	COG1414	Transcriptional regulator
H9401_RS15180	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9401_RS15185	COG0640	Transcriptional regulator
H9401_RS15195	COG1960	acyl-CoA dehydrogenase activity
H9401_RS15215	COG3314	Sporulation integral membrane protein YlbJ
H9401_RS15230	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H9401_RS15245	COG0574	Belongs to the PEP-utilizing enzyme family
H9401_RS15245	COG3848	Pyruvate phosphate dikinase
H9401_RS15250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS15265	COG5577	PFAM Coat F domain
H9401_RS15270	COG3403	YqcI/YcgG family
H9401_RS15275	COG1280	lysine exporter protein (LysE YggA)
H9401_RS15310	COG1063	alcohol dehydrogenase
H9401_RS15325	COG1027	Aspartate ammonia-lyase
H9401_RS15330	COG0252	asparaginase activity
H9401_RS15335	COG1396	sequence-specific DNA binding
H9401_RS15345	COG0322	excinuclease ABC activity
H9401_RS15350	COG0531	amino acid
H9401_RS15355	COG1114	Component of the transport system for branched-chain amino acids
H9401_RS15360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9401_RS15370	COG0281	malic enzyme
H9401_RS15390	COG0531	amino acid
H9401_RS15395	COG0697	spore germination
H9401_RS15400	COG0784	Response regulator, receiver
H9401_RS15410	COG2066	Belongs to the glutaminase family
H9401_RS15415	COG1115	amino acid carrier protein
H9401_RS15440	COG0737	Belongs to the 5'-nucleotidase family
H9401_RS15445	COG0753	catalase activity
H9401_RS15450	COG2267	carboxylic ester hydrolase activity
H9401_RS15455	COG1335	isochorismatase
H9401_RS15480	COG0583	DNA-binding transcription factor activity
H9401_RS15525	COG0415	Belongs to the DNA photolyase family
H9401_RS15530	COG0288	reversible hydration of carbon dioxide
H9401_RS15540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9401_RS15545	COG5609	conserved protein (DUF2294)
H9401_RS15555	COG1575	Belongs to the MenA family. Type 1 subfamily
H9401_RS15560	COG2267	carboxylic ester hydrolase activity
H9401_RS15565	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9401_RS15570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9401_RS15575	COG1121	(ABC) transporter
H9401_RS15605	COG0798	PFAM Bile acid sodium symporter
H9401_RS15610	COG0346	lactoylglutathione lyase activity
H9401_RS15615	COG0640	Transcriptional regulator
H9401_RS15630	COG0443	Heat shock 70 kDa protein
H9401_RS15645	COG1522	sequence-specific DNA binding
H9401_RS15660	COG0346	lactoylglutathione lyase activity
H9401_RS15685	COG2169	Transcriptional regulator
H9401_RS15730	COG2814	Major facilitator Superfamily
H9401_RS15755	COG0745	RESPONSE REGULATOR receiver
H9401_RS15760	COG5002	protein histidine kinase activity
H9401_RS15760	COG3850	Histidine kinase
H9401_RS15790	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H9401_RS15815	COG1476	TRANSCRIPTIONal
H9401_RS15830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS15835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9401_RS15845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9401_RS15850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H9401_RS15865	COG1136	(ABC) transporter
H9401_RS15870	COG0577	efflux transmembrane transporter activity
H9401_RS15890	COG5002	protein histidine kinase activity
H9401_RS15890	COG3850	Histidine kinase
H9401_RS15900	COG2364	Membrane
H9401_RS15905	COG1846	Transcriptional regulator
H9401_RS15920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS15925	COG2271	Major facilitator Superfamily
H9401_RS15930	COG1556	Lactate utilization protein
H9401_RS15945	COG0583	DNA-binding transcription factor activity
H9401_RS15955	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9401_RS15980	COG0738	Major facilitator superfamily
H9401_RS15990	COG0561	phosphatase activity
H9401_RS16000	COG1609	Transcriptional regulator
H9401_RS16005	COG0457	Tetratricopeptide repeat
H9401_RS16025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9401_RS16055	COG0534	Mate efflux family protein
H9401_RS16070	COG2814	Major facilitator Superfamily
H9401_RS16075	COG1309	transcriptional regulator
H9401_RS16090	COG0814	amino acid
H9401_RS16095	COG1760	l-serine dehydratase
H9401_RS16100	COG1760	l-serine dehydratase
H9401_RS16110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9401_RS16115	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
H9401_RS16125	COG1335	isochorismatase
H9401_RS16130	COG1522	sequence-specific DNA binding
H9401_RS16135	COG0531	amino acid
H9401_RS16150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9401_RS16170	COG1595	DNA-templated transcription, initiation
H9401_RS16185	COG0662	Cupin 2, conserved barrel domain protein
H9401_RS16195	COG2207	Transcriptional regulator
H9401_RS16195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS16250	COG0477	Major facilitator Superfamily
H9401_RS16260	COG1846	Transcriptional regulator
H9401_RS16265	COG2814	Major facilitator Superfamily
H9401_RS16280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H9401_RS16285	COG1131	(ABC) transporter
H9401_RS16305	COG2076	Multidrug Resistance protein
H9401_RS16310	COG1309	transcriptional regulator
H9401_RS16325	COG2031	fatty acid transporter
H9401_RS16335	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9401_RS16365	COG1122	ATPase activity
H9401_RS16370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9401_RS16385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9401_RS16390	COG1288	antiporter activity
H9401_RS16395	COG2356	endonuclease I
H9401_RS16410	COG3620	sequence-specific DNA binding
H9401_RS16415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9401_RS16420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9401_RS16425	COG0124	histidyl-tRNA synthetase
H9401_RS16440	COG1733	regulation of RNA biosynthetic process
H9401_RS16445	COG0778	Nitroreductase
H9401_RS16465	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS16475	COG1131	(ABC) transporter
H9401_RS16500	COG1011	Hydrolase
H9401_RS16510	COG2365	Tyrosine phosphatase family
H9401_RS16535	COG0346	lactoylglutathione lyase activity
H9401_RS16540	COG1940	carbohydrate kinase activity
H9401_RS16545	COG0738	Major facilitator superfamily
H9401_RS16550	COG0110	maltose O-acetyltransferase activity
H9401_RS16560	COG0577	efflux transmembrane transporter activity
H9401_RS16560	COG1136	(ABC) transporter
H9401_RS16570	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9401_RS16575	COG0628	permease
H9401_RS16595	COG2226	methyltransferase
H9401_RS16605	COG0477	Major facilitator Superfamily
H9401_RS16635	COG1253	flavin adenine dinucleotide binding
H9401_RS16640	COG0789	Transcriptional regulator
H9401_RS16645	COG0697	spore germination
H9401_RS16650	COG1357	PFAM Pentapeptide repeats (8 copies)
H9401_RS16655	COG3813	Protein conserved in bacteria
H9401_RS16660	COG2706	6-phosphogluconolactonase activity
H9401_RS16665	COG1070	Carbohydrate kinase
H9401_RS16675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9401_RS16680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
H9401_RS16690	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9401_RS16695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9401_RS16700	COG0604	alcohol dehydrogenase
H9401_RS16705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9401_RS16715	COG0604	alcohol dehydrogenase
H9401_RS16715	COG3321	synthase
H9401_RS16725	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS16750	COG0656	L-ascorbic acid biosynthetic process
H9401_RS16755	COG2814	Major facilitator Superfamily
H9401_RS16770	COG0346	lactoylglutathione lyase activity
H9401_RS16775	COG0814	amino acid
H9401_RS16800	COG1393	Belongs to the ArsC family
H9401_RS16810	COG1733	regulation of RNA biosynthetic process
H9401_RS16815	COG2188	Transcriptional regulator
H9401_RS16825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9401_RS16830	COG1733	regulation of RNA biosynthetic process
H9401_RS16835	COG1733	regulation of RNA biosynthetic process
H9401_RS16850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS16870	COG0384	phenazine biosynthesis protein PhzF
H9401_RS16880	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS16890	COG0318	PFAM AMP-dependent synthetase and ligase
H9401_RS16900	COG1733	regulation of RNA biosynthetic process
H9401_RS16935	COG1191	sigma factor activity
H9401_RS16950	COG1309	transcriptional regulator
H9401_RS16970	COG3152	Membrane
H9401_RS16995	COG1151	hydroxylamine reductase activity
H9401_RS17005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS17010	COG3409	Peptidoglycan-binding domain 1 protein
H9401_RS17010	COG3757	hydrolase, family 25
H9401_RS17045	COG2072	flavoprotein involved in K transport
H9401_RS17080	COG0604	alcohol dehydrogenase
H9401_RS17085	COG1113	amino acid transport
H9401_RS17090	COG2814	Major facilitator Superfamily
H9401_RS17125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9401_RS17130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9401_RS17150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS17160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS17165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS17170	COG3739	integral membrane protein
H9401_RS17175	COG0384	phenazine biosynthesis protein PhzF
H9401_RS17205	COG0583	DNA-binding transcription factor activity
H9401_RS17225	COG1193	negative regulation of DNA recombination
H9401_RS17240	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H9401_RS17245	COG1164	Oligoendopeptidase f
H9401_RS17250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9401_RS17280	COG0584	glycerophosphoryl diester phosphodiesterase
H9401_RS17305	COG0640	Transcriptional regulator
H9401_RS17310	COG0604	alcohol dehydrogenase
H9401_RS17330	COG2808	Putative FMN-binding domain
H9401_RS17335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9401_RS17345	COG0385	Bile acid
H9401_RS17350	COG0277	FAD linked oxidase domain protein
H9401_RS17385	COG1216	Glycosyl transferase, family 2
H9401_RS17390	COG1024	Enoyl-CoA hydratase
H9401_RS17400	COG1285	pathogenesis
H9401_RS17410	COG2514	catechol 2,3-dioxygenase activity
H9401_RS17415	COG2720	vancomycin resistance protein
H9401_RS17455	COG0716	FMN binding
H9401_RS17485	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS17495	COG0165	Argininosuccinate lyase
H9401_RS17510	COG4145	pantothenate transmembrane transporter activity
H9401_RS17520	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS17525	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS17535	COG1657	PFAM Prenyltransferase squalene oxidase
H9401_RS17540	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H9401_RS17545	COG2962	Rard protein
H9401_RS17550	COG3326	Membrane
H9401_RS17565	COG0489	protein tyrosine kinase activity
H9401_RS17575	COG0314	molybdopterin synthase activity
H9401_RS17580	COG0303	'Molybdopterin
H9401_RS17585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9401_RS17590	COG2116	formate transmembrane transporter activity
H9401_RS17605	COG5609	conserved protein (DUF2294)
H9401_RS17610	COG2427	Protein of unknown function (DUF1641)
H9401_RS17615	COG3383	formate dehydrogenase (NAD+) activity
H9401_RS17625	COG0697	spore germination
H9401_RS17665	COG2226	methyltransferase
H9401_RS17670	COG4166	transmembrane transport
H9401_RS17675	COG4166	transmembrane transport
H9401_RS17680	COG4166	transmembrane transport
H9401_RS17685	COG1301	dicarboxylic acid transport
H9401_RS17690	COG1316	TRANSCRIPTIONal
H9401_RS17700	COG1595	DNA-templated transcription, initiation
H9401_RS17725	COG1131	(ABC) transporter
H9401_RS17735	COG0673	inositol 2-dehydrogenase activity
H9401_RS17740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9401_RS17745	COG0187	DNA topoisomerase II activity
H9401_RS17755	COG1832	CoA-binding protein
H9401_RS17760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9401_RS17765	COG0745	RESPONSE REGULATOR receiver
H9401_RS17780	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9401_RS17785	COG4841	protein insertion into membrane
H9401_RS17790	COG0824	Thioesterase
H9401_RS17820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9401_RS17830	COG2274	protein secretion by the type I secretion system
H9401_RS17835	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H9401_RS17865	COG2211	Major facilitator Superfamily
H9401_RS17875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9401_RS17890	COG0183	Belongs to the thiolase family
H9401_RS17895	COG0318	PFAM AMP-dependent synthetase and ligase
H9401_RS17900	COG1268	BioY protein
H9401_RS17905	COG0318	PFAM AMP-dependent synthetase and ligase
H9401_RS17950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS17960	COG5002	protein histidine kinase activity
H9401_RS17965	COG0400	carboxylic ester hydrolase activity
H9401_RS17970	COG0346	lactoylglutathione lyase activity
H9401_RS17975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9401_RS17980	COG0069	glutamate synthase activity
H9401_RS17985	COG1902	pentaerythritol trinitrate reductase activity
H9401_RS17990	COG1329	Transcriptional regulator
H9401_RS17995	COG0010	Belongs to the arginase family
H9401_RS18020	COG2226	methyltransferase
H9401_RS18075	COG4846	Membrane protein involved in cytochrome C biogenesis
H9401_RS18080	COG0785	Cytochrome C biogenesis protein
H9401_RS18090	COG0583	DNA-binding transcription factor activity
H9401_RS18095	COG1380	Effector of murein hydrolase LrgA
H9401_RS18100	COG1346	cytolysis
H9401_RS18115	COG0730	response to heat
H9401_RS18125	COG3409	Peptidoglycan-binding domain 1 protein
H9401_RS18125	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9401_RS18140	COG1132	(ABC) transporter
H9401_RS18145	COG1132	(ABC) transporter
H9401_RS18180	COG3639	organic phosphonate transmembrane transporter activity
H9401_RS18185	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H9401_RS18200	COG0737	Belongs to the 5'-nucleotidase family
H9401_RS18210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9401_RS18230	COG1695	Transcriptional regulator
H9401_RS18265	COG1388	LysM domain
H9401_RS18265	COG3409	Peptidoglycan-binding domain 1 protein
H9401_RS18265	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9401_RS18270	COG4824	toxin secretion phage lysis holin
H9401_RS18430	COG1595	DNA-templated transcription, initiation
H9401_RS18475	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
H9401_RS18555	COG1396	sequence-specific DNA binding
H9401_RS18580	COG0174	glutamine synthetase
H9401_RS18585	COG0789	Transcriptional regulator
H9401_RS18590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H9401_RS18600	COG2860	membrane
H9401_RS18605	COG0464	growth
H9401_RS18635	COG3584	3D domain protein
H9401_RS18635	COG1388	LysM domain
H9401_RS18640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9401_RS18640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9401_RS18640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9401_RS18645	COG1105	Belongs to the carbohydrate kinase PfkB family
H9401_RS18650	COG1349	DNA-binding transcription factor activity
H9401_RS18660	COG2322	membrane
H9401_RS18675	COG1113	amino acid transport
H9401_RS18685	COG1408	metallophosphoesterase
H9401_RS18690	COG2116	formate transmembrane transporter activity
H9401_RS18705	COG2608	mercury ion transmembrane transporter activity
H9401_RS18710	COG1937	Protein conserved in bacteria
H9401_RS18720	COG2819	hydrolase of the alpha beta superfamily
H9401_RS18725	COG1120	ATPase activity
H9401_RS18730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS18735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS18740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS18750	COG0708	Exodeoxyribonuclease III
H9401_RS18755	COG2169	Transcriptional regulator
H9401_RS18760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9401_RS18765	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9401_RS18775	COG2364	Membrane
H9401_RS18790	COG2267	carboxylic ester hydrolase activity
H9401_RS18795	COG0346	lactoylglutathione lyase activity
H9401_RS18800	COG5001	Diguanylate cyclase
H9401_RS18800	COG3300	MHYT domain
H9401_RS18820	COG1346	cytolysis
H9401_RS18825	COG1380	Effector of murein hydrolase LrgA
H9401_RS18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9401_RS18835	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9401_RS18835	COG0596	Alpha beta hydrolase
H9401_RS18840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9401_RS18855	COG1404	Belongs to the peptidase S8 family
H9401_RS18860	COG3773	Cell wall hydrolase
H9401_RS18865	COG0562	UDP-galactopyranose mutase
H9401_RS18870	COG1368	sulfuric ester hydrolase activity
H9401_RS18875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9401_RS18885	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H9401_RS18910	COG1131	(ABC) transporter
H9401_RS18930	COG4550	Control of competence regulator ComK, YlbF/YmcA
H9401_RS18935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9401_RS18940	COG1013	pyruvate-flavodoxin oxidoreductase activity
H9401_RS18945	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
H9401_RS18945	COG0674	pyruvate-flavodoxin oxidoreductase activity
H9401_RS18955	COG2359	stage V sporulation protein S
H9401_RS18960	COG1692	metallophosphoesterase
H9401_RS18985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9401_RS18990	COG1426	Protein conserved in bacteria
H9401_RS19005	COG0300	oxidoreductase activity
H9401_RS19010	COG0612	Peptidase, M16
H9401_RS19015	COG0612	Peptidase, M16
H9401_RS19020	COG1079	Belongs to the binding-protein-dependent transport system permease family
H9401_RS19025	COG4603	Belongs to the binding-protein-dependent transport system permease family
H9401_RS19030	COG4603	Belongs to the binding-protein-dependent transport system permease family
H9401_RS19035	COG3845	ABC transporter
H9401_RS19040	COG1744	ABC transporter substrate-binding protein PnrA-like
H9401_RS19045	COG2188	Transcriptional regulator
H9401_RS19050	COG1674	ftsk spoiiie
H9401_RS19060	COG0740	serine-type endopeptidase activity
H9401_RS19065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9401_RS19080	COG0527	aspartate kinase activity
H9401_RS19085	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9401_RS19090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9401_RS19095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9401_RS19100	COG1873	PFAM PRC-barrel domain
H9401_RS19105	COG0612	Peptidase, M16
H9401_RS19110	COG0726	polysaccharide deacetylase
H9401_RS19125	COG0196	riboflavin kinase activity
H9401_RS19130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9401_RS19140	COG1550	Protein conserved in bacteria
H9401_RS19150	COG1358	cellular component organization or biogenesis
H9401_RS19155	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H9401_RS19160	COG0195	Participates in both transcription termination and antitermination
H9401_RS19180	COG0750	zinc metalloprotease
H9401_RS19190	COG4589	Belongs to the CDS family
H9401_RS19195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9401_RS19205	COG0528	UMP kinase activity
H9401_RS19235	COG4974	Belongs to the 'phage' integrase family
H9401_RS19245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9401_RS19255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9401_RS19295	COG1837	Belongs to the UPF0109 family
H9401_RS19305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9401_RS19315	COG0552	protein localization to endoplasmic reticulum
H9401_RS19320	COG1196	nuclear chromosome segregation
H9401_RS19330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9401_RS19335	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS19340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9401_RS19355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9401_RS19360	COG1461	Dihydroxyacetone kinase
H9401_RS19365	COG1302	Protein conserved in bacteria
H9401_RS19380	COG1564	THIamine pyrophosphokinase
H9401_RS19385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9401_RS19390	COG1162	GTPase activity
H9401_RS19395	COG2815	serine threonine protein kinase
H9401_RS19395	COG0515	serine threonine protein kinase
H9401_RS19400	COG0631	protein serine/threonine phosphatase activity
H9401_RS19410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9401_RS19410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9401_RS19420	COG0242	peptide deformylase activity
H9401_RS19425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9401_RS19430	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9401_RS19450	COG1561	YicC-like family, N-terminal region
H9401_RS19455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9401_RS19465	COG0006	proline dipeptidase activity
H9401_RS19480	COG3069	C4-dicarboxylate transmembrane transporter activity
H9401_RS19545	COG0564	pseudouridine synthase activity
H9401_RS19565	COG3599	regulation of cell shape
H9401_RS19570	COG2302	S4 RNA-binding domain
H9401_RS19575	COG0762	integral membrane protein
H9401_RS19585	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9401_RS19590	COG1496	oxidoreductase activity
H9401_RS19595	COG1873	PFAM PRC-barrel domain
H9401_RS19600	COG1191	sigma factor activity
H9401_RS19605	COG1191	sigma factor activity
H9401_RS19615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9401_RS19620	COG0849	cell division
H9401_RS19625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9401_RS19630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9401_RS19640	COG0772	Belongs to the SEDS family
H9401_RS19655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9401_RS19660	COG0768	penicillin binding
H9401_RS19665	COG0768	penicillin binding
H9401_RS19670	COG4839	cell division protein FtsL
H9401_RS19685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9401_RS19700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9401_RS19705	COG1399	metal-binding, possibly nucleic acid-binding protein
H9401_RS19755	COG4824	toxin secretion phage lysis holin
H9401_RS19850	COG1802	Transcriptional regulator
H9401_RS19850	COG4626	Terminase
H9401_RS19875	COG0582	viral genome integration into host DNA
H9401_RS19945	COG0756	dUTP diphosphatase activity
H9401_RS19955	COG1191	sigma factor activity
H9401_RS19980	COG1484	DNA-dependent DNA replication
H9401_RS20010	COG1396	sequence-specific DNA binding
H9401_RS20020	COG1396	sequence-specific DNA binding
H9401_RS20035	COG0582	viral genome integration into host DNA
H9401_RS20045	COG3480	Lon protease (S16) C-terminal proteolytic domain
H9401_RS20050	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9401_RS20055	COG3314	Sporulation integral membrane protein YlbJ
H9401_RS20065	COG0742	ribosomal rna small subunit methyltransferase
H9401_RS20080	COG3679	Belongs to the UPF0342 family
H9401_RS20085	COG0406	alpha-ribazole phosphatase activity
H9401_RS20100	COG2340	Cysteine-rich secretory protein family
H9401_RS20115	COG3336	cytochrome c oxidase
H9401_RS20150	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H9401_RS20155	COG0772	Belongs to the SEDS family
H9401_RS20165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H9401_RS20170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9401_RS20180	COG4896	Protein conserved in bacteria
H9401_RS20195	COG1217	gtp-binding protein TYPA
H9401_RS20205	COG0483	inositol monophosphate 1-phosphatase activity
H9401_RS20225	COG1982	Orn Lys Arg decarboxylase major
H9401_RS20270	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9401_RS20275	COG0022	dehydrogenase e1 component
H9401_RS20280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9401_RS20290	COG0242	peptide deformylase activity
H9401_RS20295	COG0561	phosphatase activity
H9401_RS20305	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9401_RS20310	COG0569	domain protein
H9401_RS20330	COG0583	DNA-binding transcription factor activity
H9401_RS20335	COG0517	IMP dehydrogenase activity
H9401_RS20345	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H9401_RS20355	COG4703	Protein of unknown function (DUF1797)
H9401_RS20370	COG2200	EAL domain
H9401_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS20380	COG1408	metallophosphoesterase
H9401_RS20390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9401_RS20430	COG2814	Major facilitator Superfamily
H9401_RS20455	COG3209	COG3209 Rhs family protein
H9401_RS20465	COG2205	protein histidine kinase activity
H9401_RS20475	COG0436	Aminotransferase
H9401_RS20480	COG1609	Transcriptional regulator
H9401_RS20485	COG3833	ABC-type maltose transport systems, permease component
H9401_RS20490	COG1175	transmembrane transport
H9401_RS20495	COG2182	Extracellular solute-binding protein
H9401_RS20505	COG0366	Alpha amylase catalytic
H9401_RS20510	COG3842	ATPase activity
H9401_RS20550	COG0183	Belongs to the thiolase family
H9401_RS20590	COG1695	Transcriptional regulator
H9401_RS20595	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS20605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H9401_RS20615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9401_RS20620	COG0436	Aminotransferase
H9401_RS20640	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H9401_RS20660	COG2199	diguanylate cyclase activity
H9401_RS20665	COG0778	Nitroreductase
H9401_RS20690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9401_RS20690	COG1263	PTS System
H9401_RS20690	COG2190	(PTS) system
H9401_RS20695	COG3711	transcriptional antiterminator
H9401_RS20705	COG2188	Transcriptional regulator
H9401_RS20715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9401_RS20745	COG1547	Domain of unknown function (DUF309)
H9401_RS20750	COG0456	acetyltransferase
H9401_RS20760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9401_RS20765	COG4086	secreted protein
H9401_RS20770	COG0561	phosphatase activity
H9401_RS20775	COG0697	spore germination
H9401_RS20790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9401_RS20815	COG0733	neurotransmitter:sodium symporter activity
H9401_RS20835	COG1686	Belongs to the peptidase S11 family
H9401_RS20840	COG1725	Transcriptional regulator
H9401_RS20845	COG1131	(ABC) transporter
H9401_RS20865	COG1846	Transcriptional regulator
H9401_RS20880	COG0598	Magnesium transport protein CorA
H9401_RS20905	COG4974	Belongs to the 'phage' integrase family
H9401_RS20915	COG0735	belongs to the Fur family
H9401_RS20920	COG1300	Membrane
H9401_RS20940	COG0667	Aldo Keto reductase
H9401_RS20945	COG0656	L-ascorbic acid biosynthetic process
H9401_RS20950	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9401_RS20950	COG0456	acetyltransferase
H9401_RS20960	COG0737	Belongs to the 5'-nucleotidase family
H9401_RS20960	COG4085	toxin activity
H9401_RS20960	COG1525	nuclease
H9401_RS20970	COG0596	Alpha beta hydrolase
H9401_RS20975	COG2056	Na+-H+ antiporter family
H9401_RS20980	COG1609	Transcriptional regulator
H9401_RS20985	COG0456	acetyltransferase
H9401_RS20990	COG1073	alpha beta
H9401_RS21005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9401_RS21005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9401_RS21010	COG0307	riboflavin synthase, alpha
H9401_RS21035	COG4106	trans-aconitate 2-methyltransferase activity
H9401_RS21040	COG2226	methyltransferase
H9401_RS21040	COG1073	alpha beta
H9401_RS21055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9401_RS21065	COG1757	Na H antiporter
H9401_RS21070	COG0737	Belongs to the 5'-nucleotidase family
H9401_RS21080	COG1522	sequence-specific DNA binding
H9401_RS21100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9401_RS21110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H9401_RS21125	COG0300	oxidoreductase activity
H9401_RS21130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS21140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9401_RS21145	COG1760	l-serine dehydratase
H9401_RS21150	COG1760	l-serine dehydratase
H9401_RS21175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9401_RS21185	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9401_RS21190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS21205	COG1376	ErfK ybiS ycfS ynhG family protein
H9401_RS21210	COG4129	membrane
H9401_RS21215	COG1126	abc transporter atp-binding protein
H9401_RS21220	COG0765	amino acid transport
H9401_RS21225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9401_RS21250	COG0772	Belongs to the SEDS family
H9401_RS21260	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9401_RS21265	COG0022	dehydrogenase e1 component
H9401_RS21270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9401_RS21275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9401_RS21290	COG0280	phosphate acetyltransferase
H9401_RS21300	COG3290	protein histidine kinase activity
H9401_RS21300	COG3829	transcription factor binding
H9401_RS21310	COG0584	glycerophosphoryl diester phosphodiesterase
H9401_RS21315	COG3093	addiction module antidote protein HigA
H9401_RS21325	COG0745	RESPONSE REGULATOR receiver
H9401_RS21330	COG0750	zinc metalloprotease
H9401_RS21335	COG0497	DNA recombination
H9401_RS21345	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H9401_RS21355	COG0142	geranyltranstransferase activity
H9401_RS21380	COG1302	Protein conserved in bacteria
H9401_RS21385	COG0439	Biotin carboxylase
H9401_RS21390	COG0511	ligase activity, forming carbon-carbon bonds
H9401_RS21435	COG3854	ATPases associated with a variety of cellular activities
H9401_RS21460	COG0006	proline dipeptidase activity
H9401_RS21475	COG3872	metal-dependent enzyme
H9401_RS21485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9401_RS21505	COG0095	Lipoate-protein ligase
H9401_RS21510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9401_RS21515	COG1609	Transcriptional regulator
H9401_RS21525	COG2076	Multidrug Resistance protein
H9401_RS21530	COG2076	Multidrug Resistance protein
H9401_RS21570	COG1131	(ABC) transporter
H9401_RS21575	COG1725	Transcriptional regulator
H9401_RS21605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9401_RS21660	COG4970	Tfp pilus assembly protein FimT
H9401_RS21670	COG1459	type II secretion system
H9401_RS21675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9401_RS21725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9401_RS21730	COG1410	methionine synthase
H9401_RS21730	COG0646	methionine synthase
H9401_RS21735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9401_RS21735	COG0646	methionine synthase
H9401_RS21745	COG0626	cystathionine gamma-synthase activity
H9401_RS21750	COG0626	cystathionine gamma-synthase activity
H9401_RS21775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS21785	COG1940	carbohydrate kinase activity
H9401_RS21790	COG4483	Protein conserved in bacteria
H9401_RS21795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9401_RS21800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9401_RS21805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H9401_RS21810	COG0704	Plays a role in the regulation of phosphate uptake
H9401_RS21820	COG0581	inorganic phosphate transmembrane transporter activity
H9401_RS21825	COG0573	inorganic phosphate transmembrane transporter activity
H9401_RS21830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9401_RS21835	COG0768	penicillin binding
H9401_RS21840	COG0477	Major facilitator Superfamily
H9401_RS21845	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9401_RS21870	COG0735	belongs to the Fur family
H9401_RS21875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9401_RS21880	COG1121	(ABC) transporter
H9401_RS21885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS21915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9401_RS21920	COG2384	SAM-dependent methyltransferase
H9401_RS21925	COG2010	Cytochrome c
H9401_RS21930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9401_RS21935	COG0358	DNA primase activity
H9401_RS21955	COG0517	IMP dehydrogenase activity
H9401_RS21970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9401_RS21975	COG0295	cytidine deaminase activity
H9401_RS21980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9401_RS21990	COG1480	7TM receptor with intracellular HD hydrolase
H9401_RS21995	COG1702	phosphate starvation-inducible protein PhoH
H9401_RS22015	COG1610	YqeY-like protein
H9401_RS22020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9401_RS22025	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9401_RS22030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9401_RS22060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9401_RS22065	COG1733	regulation of RNA biosynthetic process
H9401_RS22090	COG1466	dna polymerase III delta subunit
H9401_RS22100	COG2333	competence protein COMEC
H9401_RS22100	COG0658	competence protein
H9401_RS22105	COG2131	deaminase
H9401_RS22110	COG1555	photosystem II stabilization
H9401_RS22110	COG1596	polysaccharide export
H9401_RS22115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9401_RS22120	COG2226	methyltransferase
H9401_RS22125	COG0799	negative regulation of ribosome biogenesis
H9401_RS22130	COG1713	HD superfamily hydrolase involved in NAD metabolism
H9401_RS22140	COG1534	Rna-binding protein
H9401_RS22150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9401_RS22155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H9401_RS22180	COG1595	DNA-templated transcription, initiation
H9401_RS22190	COG0778	Nitroreductase
H9401_RS22195	COG2357	RelA SpoT domain protein
H9401_RS22205	COG1785	Belongs to the alkaline phosphatase family
H9401_RS22215	COG2267	carboxylic ester hydrolase activity
H9401_RS22250	COG1404	Belongs to the peptidase S8 family
H9401_RS22255	COG3186	Phenylalanine-4-hydroxylase
H9401_RS22265	COG2514	catechol 2,3-dioxygenase activity
H9401_RS22270	COG2514	catechol 2,3-dioxygenase activity
H9401_RS22275	COG2259	Doxx family
H9401_RS22315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS22325	COG1454	alcohol dehydrogenase
H9401_RS22325	COG1012	belongs to the aldehyde dehydrogenase family
H9401_RS22330	COG0626	cystathionine gamma-synthase activity
H9401_RS22335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9401_RS22360	COG0768	penicillin binding
H9401_RS22375	COG0826	peptidase U32
H9401_RS22380	COG0826	peptidase U32
H9401_RS22385	COG4122	O-methyltransferase activity
H9401_RS22390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9401_RS22410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9401_RS22420	COG0628	permease
H9401_RS22440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9401_RS22450	COG0482	sulfurtransferase activity
H9401_RS22455	COG1104	cysteine desulfurase activity
H9401_RS22460	COG1959	2 iron, 2 sulfur cluster binding
H9401_RS22465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9401_RS22475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9401_RS22500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9401_RS22510	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9401_RS22510	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9401_RS22515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9401_RS22520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9401_RS22520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9401_RS22530	COG2244	polysaccharide biosynthetic process
H9401_RS22535	COG2323	membrane
H9401_RS22545	COG1862	Preprotein translocase
H9401_RS22575	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H9401_RS22585	COG0697	spore germination
H9401_RS22590	COG0697	spore germination
H9401_RS22595	COG0640	Transcriptional regulator
H9401_RS22620	COG0157	Belongs to the NadC ModD family
H9401_RS22625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9401_RS22630	COG1104	cysteine desulfurase activity
H9401_RS22635	COG1827	regulation of RNA biosynthetic process
H9401_RS22640	COG2258	MOSC domain
H9401_RS22645	COG0077	Prephenate dehydratase
H9401_RS22650	COG0577	efflux transmembrane transporter activity
H9401_RS22655	COG0577	efflux transmembrane transporter activity
H9401_RS22660	COG1136	(ABC) transporter
H9401_RS22665	COG5002	protein histidine kinase activity
H9401_RS22675	COG0745	RESPONSE REGULATOR receiver
H9401_RS22680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9401_RS22685	COG3290	protein histidine kinase activity
H9401_RS22695	COG2868	ribosomal protein
H9401_RS22705	COG1530	ribonuclease E activity
H9401_RS22710	COG1994	Peptidase M50
H9401_RS22715	COG0739	heme binding
H9401_RS22720	COG2894	cell division
H9401_RS22740	COG1077	Cell shape determining protein MreB Mrl
H9401_RS22760	COG0285	dihydrofolate synthase activity
H9401_RS22765	COG0525	valine-tRNA ligase activity
H9401_RS22775	COG1388	LysM domain
H9401_RS22785	COG0113	porphobilinogen synthase activity
H9401_RS22790	COG1587	Uroporphyrinogen-III synthase
H9401_RS22810	COG1846	Transcriptional regulator
H9401_RS22815	COG1764	response to oxidative stress
H9401_RS22830	COG1067	ATP-dependent peptidase activity
H9401_RS22830	COG0470	DNA polymerase III
H9401_RS22880	COG0622	Phosphoesterase
H9401_RS22895	COG5401	PFAM Sporulation and spore germination
H9401_RS22915	COG1309	transcriptional regulator
H9401_RS22930	COG2197	response regulator
H9401_RS22935	COG2233	PERMEase
H9401_RS22945	COG0402	S-adenosylhomocysteine deaminase activity
H9401_RS22950	COG0402	S-adenosylhomocysteine deaminase activity
H9401_RS22960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9401_RS22970	COG0444	Belongs to the ABC transporter superfamily
H9401_RS22975	COG4608	Belongs to the ABC transporter superfamily
H9401_RS22980	COG3275	phosphorelay sensor kinase activity
H9401_RS22985	COG3279	Response regulator of the LytR AlgR family
H9401_RS23000	COG1983	PspC domain protein
H9401_RS23005	COG1396	sequence-specific DNA binding
H9401_RS23010	COG0697	spore germination
H9401_RS23020	COG1959	2 iron, 2 sulfur cluster binding
H9401_RS23025	COG1668	transmembrane transport
H9401_RS23030	COG4152	abc transporter atp-binding protein
H9401_RS23035	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
H9401_RS23045	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9401_RS23050	COG1876	peptidase activity
H9401_RS23055	COG0824	Thioesterase
H9401_RS23060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9401_RS23065	COG1053	succinate dehydrogenase
H9401_RS23070	COG2009	succinate dehydrogenase
H9401_RS23075	COG1719	4-vinyl reductase, 4VR
H9401_RS23085	COG3118	belongs to the thioredoxin family
H9401_RS23090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9401_RS23095	COG2086	electron transfer activity
H9401_RS23100	COG1024	Enoyl-CoA hydratase
H9401_RS23105	COG1309	transcriptional regulator
H9401_RS23110	COG0318	PFAM AMP-dependent synthetase and ligase
H9401_RS23130	COG2318	DinB family
H9401_RS23160	COG1131	(ABC) transporter
H9401_RS23165	COG2205	protein histidine kinase activity
H9401_RS23170	COG0745	RESPONSE REGULATOR receiver
H9401_RS23180	COG4895	conserved protein (DUF2196)
H9401_RS23185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9401_RS23200	COG4509	Sortase family
H9401_RS23205	COG1120	ATPase activity
H9401_RS23220	COG5386	Cell surface protein
H9401_RS23230	COG5386	Cell surface protein
H9401_RS23235	COG1114	Component of the transport system for branched-chain amino acids
H9401_RS23240	COG1187	pseudouridine synthase activity
H9401_RS23255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9401_RS23255	COG1796	DNA polymerase
H9401_RS23260	COG1286	toxin biosynthetic process
H9401_RS23305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9401_RS23315	COG1418	mRNA catabolic process
H9401_RS23340	COG2814	Major facilitator Superfamily
H9401_RS23345	COG1566	PFAM secretion protein HlyD family protein
H9401_RS23350	COG1309	transcriptional regulator
H9401_RS23355	COG1363	Peptidase, m42
H9401_RS23380	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9401_RS23390	COG1484	DNA-dependent DNA replication
H9401_RS23395	COG3611	Membrane attachment protein
H9401_RS23405	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9401_RS23410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9401_RS23415	COG0237	dephospho-CoA kinase activity
H9401_RS23420	COG1971	Probably functions as a manganese efflux pump
H9401_RS23430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9401_RS23430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9401_RS23435	COG5002	protein histidine kinase activity
H9401_RS23440	COG0745	RESPONSE REGULATOR receiver
H9401_RS23460	COG0538	isocitrate dehydrogenase activity
H9401_RS23465	COG0372	Belongs to the citrate synthase family
H9401_RS23480	COG0628	permease
H9401_RS23485	COG3030	protein affecting phage T7 exclusion by the F plasmid
H9401_RS23510	COG1725	Transcriptional regulator
H9401_RS23515	COG0281	malic enzyme
H9401_RS23520	COG0587	DNA-directed DNA polymerase activity
H9401_RS23535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9401_RS23555	COG4109	DRTGG domain
H9401_RS23570	COG0006	proline dipeptidase activity
H9401_RS23605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS23610	COG0662	Cupin 2, conserved barrel domain protein
H9401_RS23620	COG1476	TRANSCRIPTIONal
H9401_RS23635	COG1028	Short-chain dehydrogenase reductase Sdr
H9401_RS23640	COG0589	response to stress
H9401_RS23680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS23700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9401_RS23705	COG0827	DNA restriction-modification system
H9401_RS23710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H9401_RS23715	COG3874	Sporulation protein YtfJ
H9401_RS23730	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H9401_RS23740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9401_RS23755	COG1104	cysteine desulfurase activity
H9401_RS23765	COG0583	DNA-binding transcription factor activity
H9401_RS23770	COG0697	spore germination
H9401_RS23780	COG1956	GAF domain-containing protein
H9401_RS23785	COG0626	cystathionine gamma-synthase activity
H9401_RS23815	COG1595	DNA-templated transcription, initiation
H9401_RS23825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9401_RS23830	COG0454	-acetyltransferase
H9401_RS23835	COG0517	IMP dehydrogenase activity
H9401_RS23840	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9401_RS23850	COG0745	RESPONSE REGULATOR receiver
H9401_RS23860	COG0666	response to abiotic stimulus
H9401_RS23895	COG1609	Transcriptional regulator
H9401_RS23905	COG4851	CamS sex pheromone cAM373 precursor
H9401_RS23910	COG3118	belongs to the thioredoxin family
H9401_RS23920	COG2309	aminopeptidase activity
H9401_RS23940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS23955	COG1674	ftsk spoiiie
H9401_RS23965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9401_RS23970	COG4848	Belongs to the UPF0354 family
H9401_RS23975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9401_RS23980	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
H9401_RS23985	COG1363	Peptidase, m42
H9401_RS23995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS24010	COG0510	thiamine kinase activity
H9401_RS24015	COG1523	belongs to the glycosyl hydrolase 13 family
H9401_RS24030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9401_RS24035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9401_RS24040	COG1349	DNA-binding transcription factor activity
H9401_RS24045	COG1187	pseudouridine synthase activity
H9401_RS24050	COG2244	polysaccharide biosynthetic process
H9401_RS24055	COG2081	HI0933 family
H9401_RS24060	COG2814	Major facilitator Superfamily
H9401_RS24070	COG3832	glyoxalase III activity
H9401_RS24090	COG1329	Transcriptional regulator
H9401_RS24100	COG4975	Glucose uptake
H9401_RS24115	COG0314	molybdopterin synthase activity
H9401_RS24120	COG1763	Mo-molybdopterin cofactor biosynthetic process
H9401_RS24125	COG0303	'Molybdopterin
H9401_RS24135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9401_RS24160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9401_RS24170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9401_RS24215	COG2814	Major facilitator Superfamily
H9401_RS24220	COG0475	glutathione-regulated potassium exporter activity
H9401_RS24225	COG0490	domain, Protein
H9401_RS24230	COG0582	viral genome integration into host DNA
H9401_RS24240	COG1136	(ABC) transporter
H9401_RS24260	COG1242	4 iron, 4 sulfur cluster binding
H9401_RS24265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H9401_RS24270	COG1131	(ABC) transporter
H9401_RS24280	COG1794	racemase activity, acting on amino acids and derivatives
H9401_RS24300	COG2267	carboxylic ester hydrolase activity
H9401_RS24305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9401_RS24310	COG0671	phosphoesterase, PA-phosphatase related
H9401_RS24315	COG0438	transferase activity, transferring glycosyl groups
H9401_RS24325	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9401_RS24380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9401_RS24385	COG5002	protein histidine kinase activity
H9401_RS24390	COG4191	Histidine kinase
H9401_RS24395	COG2267	carboxylic ester hydrolase activity
H9401_RS24415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9401_RS24420	COG1116	anion transmembrane transporter activity
H9401_RS24425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9401_RS24450	COG0494	nUDIX hydrolase
H9401_RS24480	COG0288	reversible hydration of carbon dioxide
H9401_RS24485	COG1271	oxidase subunit
H9401_RS24490	COG1294	oxidase, subunit
H9401_RS24510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS24535	COG1842	Phage shock protein A
H9401_RS24570	COG5002	protein histidine kinase activity
H9401_RS24575	COG0745	RESPONSE REGULATOR receiver
H9401_RS24605	COG1597	lipid kinase activity
H9401_RS24640	COG0586	Pfam SNARE associated Golgi protein
H9401_RS24650	COG0577	efflux transmembrane transporter activity
H9401_RS24655	COG1136	(ABC) transporter
H9401_RS24660	COG3708	Transcriptional regulator
H9401_RS24660	COG2207	Transcriptional regulator
H9401_RS24665	COG0745	RESPONSE REGULATOR receiver
H9401_RS24670	COG2205	protein histidine kinase activity
H9401_RS24675	COG0577	efflux transmembrane transporter activity
H9401_RS24685	COG0577	efflux transmembrane transporter activity
H9401_RS24690	COG0577	efflux transmembrane transporter activity
H9401_RS24695	COG1136	(ABC) transporter
H9401_RS24715	COG2188	Transcriptional regulator
H9401_RS24735	COG3964	amidohydrolase
H9401_RS24765	COG4948	Mandelate Racemase Muconate Lactonizing
H9401_RS24775	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H9401_RS24780	COG0596	Alpha beta hydrolase
H9401_RS24785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9401_RS24790	COG1169	isochorismate synthase
H9401_RS24795	COG1575	Belongs to the MenA family. Type 1 subfamily
H9401_RS24800	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9401_RS24825	COG0058	SHG alpha-glucan phosphorylase activity
H9401_RS24830	COG0297	glycogen (starch) synthase activity
H9401_RS24835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9401_RS24945	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9401_RS24980	COG1285	pathogenesis
H9401_RS24985	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9401_RS24995	COG0166	Belongs to the GPI family
H9401_RS25005	COG2155	Conserved Protein
H9401_RS25010	COG1098	S1 RNA binding domain
H9401_RS25015	COG0436	Aminotransferase
H9401_RS25020	COG1522	sequence-specific DNA binding
H9401_RS25025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9401_RS25030	COG2267	carboxylic ester hydrolase activity
H9401_RS25040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9401_RS25060	COG5018	Exonuclease
H9401_RS25065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9401_RS25085	COG2050	protein possibly involved in aromatic compounds catabolism
H9401_RS25095	COG1268	BioY protein
H9401_RS25105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9401_RS25110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9401_RS25125	COG3584	3D domain protein
H9401_RS25140	COG1252	NADH dehydrogenase
H9401_RS25155	COG3708	Transcriptional regulator
H9401_RS25170	COG1683	Conserved Protein
H9401_RS25190	COG0316	Belongs to the HesB IscA family
H9401_RS25205	COG1252	NADH dehydrogenase
H9401_RS25220	COG0390	transport system, permease component
H9401_RS25225	COG2824	Alkylphosphonate utilization operon protein PhnA
H9401_RS25265	COG4837	Protein of unknown function (DUF1462)
H9401_RS25270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9401_RS25280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9401_RS25285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9401_RS25295	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9401_RS25300	COG0647	UMP catabolic process
H9401_RS25310	COG2445	Protein of unknown function DUF86
H9401_RS25315	COG1494	fructose-1,6-bisphosphatase
H9401_RS25335	COG4470	Protein conserved in bacteria
H9401_RS25345	COG0789	Transcriptional regulator
H9401_RS25350	COG4377	Putative membrane peptidase family (DUF2324)
H9401_RS25375	COG0739	heme binding
H9401_RS25385	COG3377	Domain of unknown function (DUF1805)
H9401_RS25390	COG0737	Belongs to the 5'-nucleotidase family
H9401_RS25400	COG1695	Transcriptional regulator
H9401_RS25415	COG0719	Fe-S assembly protein
H9401_RS25420	COG0822	iron-sulfur transferase activity
H9401_RS25425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9401_RS25430	COG0719	Fe-S assembly protein
H9401_RS25435	COG0396	ATPase activity
H9401_RS25440	COG1464	Belongs to the NlpA lipoprotein family
H9401_RS25450	COG2011	ABC-type metal ion transport system permease component
H9401_RS25455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9401_RS25470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9401_RS25475	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H9401_RS25485	COG1393	Belongs to the ArsC family
H9401_RS25535	COG0039	L-malate dehydrogenase activity
H9401_RS25560	COG1309	transcriptional regulator
H9401_RS25565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9401_RS25570	COG1960	acyl-CoA dehydrogenase activity
H9401_RS25580	COG0183	Belongs to the thiolase family
H9401_RS25585	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9401_RS25585	COG1024	Enoyl-CoA hydratase
H9401_RS25595	COG1686	Belongs to the peptidase S11 family
H9401_RS25610	COG0011	TIGRFAM Protein of
H9401_RS25615	COG0840	transmembrane signaling receptor activity
H9401_RS25635	COG2814	Major facilitator Superfamily
H9401_RS25640	COG0531	amino acid
H9401_RS25650	COG0706	membrane insertase activity
H9401_RS25660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9401_RS25695	COG0586	Pfam SNARE associated Golgi protein
H9401_RS25705	COG1376	ErfK ybiS ycfS ynhG family protein
H9401_RS25710	COG0745	RESPONSE REGULATOR receiver
H9401_RS25715	COG5002	protein histidine kinase activity
H9401_RS25740	COG2151	metal-sulfur cluster biosynthetic enzyme
H9401_RS25745	COG3227	Zinc metalloprotease (Elastase)
H9401_RS25750	COG1741	Belongs to the pirin family
H9401_RS25765	COG0475	glutathione-regulated potassium exporter activity
H9401_RS25770	COG0490	domain, Protein
H9401_RS25780	COG1115	amino acid carrier protein
H9401_RS25785	COG0783	Belongs to the Dps family
H9401_RS25800	COG1611	Belongs to the LOG family
H9401_RS25815	COG2311	Membrane
H9401_RS25825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS25830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS25835	COG1115	amino acid carrier protein
H9401_RS25840	COG1115	amino acid carrier protein
H9401_RS25845	COG2910	NAD(P)H-binding
H9401_RS25860	COG0656	L-ascorbic acid biosynthetic process
H9401_RS25865	COG2814	Major facilitator Superfamily
H9401_RS25870	COG1733	regulation of RNA biosynthetic process
H9401_RS25880	COG1252	NADH dehydrogenase
H9401_RS25885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9401_RS25890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9401_RS25900	COG0840	transmembrane signaling receptor activity
H9401_RS25900	COG3290	protein histidine kinase activity
H9401_RS25910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9401_RS25915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9401_RS25930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9401_RS25980	COG0557	exoribonuclease II activity
H9401_RS25985	COG1647	Serine aminopeptidase, S33
H9401_RS25990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9401_RS25995	COG1346	cytolysis
H9401_RS26095	COG4695	Portal protein
H9401_RS26120	COG4974	Belongs to the 'phage' integrase family
H9401_RS26130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9401_RS26135	COG0149	triose-phosphate isomerase activity
H9401_RS26145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9401_RS26160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9401_RS26185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9401_RS26200	COG2323	membrane
H9401_RS26205	COG0740	serine-type endopeptidase activity
H9401_RS26210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9401_RS26220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H9401_RS26230	COG1051	belongs to the nudix hydrolase family
H9401_RS26240	COG0492	ferredoxin-NADP+ reductase activity
H9401_RS26245	COG0457	Tetratricopeptide repeat
H9401_RS26250	COG0110	maltose O-acetyltransferase activity
H9401_RS26270	COG1950	PFAM Membrane protein of
H9401_RS26280	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9401_RS26285	COG0556	nucleotide-excision repair
H9401_RS26305	COG0789	Transcriptional regulator
H9401_RS26330	COG2855	membrane
H9401_RS26335	COG0583	DNA-binding transcription factor activity
H9401_RS26345	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9401_RS26350	COG0488	(ABC) transporter
H9401_RS26360	COG1132	(ABC) transporter
H9401_RS26370	COG0793	Belongs to the peptidase S41A family
H9401_RS26370	COG3409	Peptidoglycan-binding domain 1 protein
H9401_RS26375	COG2177	Part of the ABC transporter FtsEX involved in
H9401_RS26380	COG2884	Cell division ATP-binding protein ftsE
H9401_RS26395	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H9401_RS26400	COG0653	protein targeting
H9401_RS26405	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9401_RS26410	COG1278	Cold shock
H9401_RS26415	COG1040	competence protein
H9401_RS26420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H9401_RS26425	COG0791	NLP P60 protein
H9401_RS26425	COG1388	LysM domain
H9401_RS26430	COG1733	regulation of RNA biosynthetic process
H9401_RS26440	COG1307	EDD domain protein, DegV family
H9401_RS26445	COG1739	Uncharacterized protein family UPF0029
H9401_RS26450	COG1316	TRANSCRIPTIONal
H9401_RS26455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9401_RS26460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H9401_RS26465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9401_RS26475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9401_RS26475	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H9401_RS26490	COG3394	polysaccharide catabolic process
H9401_RS26495	COG1486	melibiose metabolic process
H9401_RS26500	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9401_RS26505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9401_RS26515	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H9401_RS26520	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9401_RS26525	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9401_RS26535	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9401_RS26540	COG1301	dicarboxylic acid transport
H9401_RS26550	COG0346	lactoylglutathione lyase activity
H9401_RS26555	COG1511	domain protein
H9401_RS26560	COG0583	DNA-binding transcription factor activity
H9401_RS26565	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H9401_RS26580	COG1271	oxidase subunit
H9401_RS26585	COG1294	oxidase, subunit
H9401_RS26590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9401_RS26600	COG1620	l-lactate permease
H9401_RS26610	COG2389	metal-binding protein
H9401_RS26620	COG1368	sulfuric ester hydrolase activity
H9401_RS26635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9401_RS26645	COG1215	transferase activity, transferring glycosyl groups
H9401_RS26655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9401_RS26660	COG3584	3D domain protein
H9401_RS26660	COG1388	LysM domain
H9401_RS26685	COG4715	Zinc finger, swim domain protein
H9401_RS26690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9401_RS26730	COG0577	efflux transmembrane transporter activity
H9401_RS26735	COG1136	(ABC) transporter
H9401_RS26770	COG5002	protein histidine kinase activity
H9401_RS26775	COG0745	RESPONSE REGULATOR receiver
H9401_RS26780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9401_RS26800	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9401_RS26805	COG1134	teichoic acid transport
H9401_RS26810	COG1682	transport, permease protein
H9401_RS26815	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9401_RS26860	COG1609	Transcriptional regulator
H9401_RS26875	COG0739	heme binding
H9401_RS26890	COG3279	Response regulator of the LytR AlgR family
H9401_RS26895	COG4555	ABC transporter
H9401_RS26900	COG2385	sporulation resulting in formation of a cellular spore
H9401_RS26915	COG4836	Membrane
H9401_RS26920	COG1007	ATP synthesis coupled electron transport
H9401_RS26925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9401_RS26930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9401_RS26940	COG0839	Belongs to the complex I subunit 6 family
H9401_RS26955	COG0649	NAD binding
H9401_RS26960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9401_RS26975	COG3300	MHYT domain
H9401_RS26975	COG5001	Diguanylate cyclase
H9401_RS27025	COG0356	it plays a direct role in the translocation of protons across the membrane
H9401_RS27060	COG0698	ribose 5-phosphate isomerase
H9401_RS27070	COG2190	(PTS) system
H9401_RS27075	COG2259	Doxx family
H9401_RS27080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H9401_RS27095	COG0009	L-threonylcarbamoyladenylate synthase
H9401_RS27110	COG2890	protein-(glutamine-N5) methyltransferase activity
H9401_RS27130	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9401_RS27135	COG1494	fructose-1,6-bisphosphatase
H9401_RS27155	COG4821	SIS domain
H9401_RS27165	COG3343	RNA polymerase activity
H9401_RS27175	COG1960	acyl-CoA dehydrogenase activity
H9401_RS27180	COG1960	acyl-CoA dehydrogenase activity
H9401_RS27185	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9401_RS27190	COG0183	Belongs to the thiolase family
H9401_RS27195	COG0247	lactate metabolic process
H9401_RS27195	COG2181	nitrate reductase activity
H9401_RS27200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9401_RS27210	COG5001	Diguanylate cyclase
H9401_RS27210	COG3300	MHYT domain
H9401_RS27225	COG2197	response regulator
H9401_RS27230	COG4585	Histidine kinase
H9401_RS27235	COG0842	Transport permease protein
H9401_RS27240	COG1131	(ABC) transporter
H9401_RS27245	COG0024	Methionine aminopeptidase
H9401_RS27260	COG2234	aminopeptidase activity
H9401_RS27280	COG1595	DNA-templated transcription, initiation
H9401_RS27285	COG0018	arginyl-trna synthetase
H9401_RS27290	COG4506	Protein conserved in bacteria
H9401_RS27295	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9401_RS27315	COG0010	Belongs to the arginase family
H9401_RS27325	COG2814	Major facilitator Superfamily
H9401_RS27330	COG0789	Transcriptional regulator
H9401_RS27335	COG0584	glycerophosphoryl diester phosphodiesterase
H9401_RS27340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9401_RS27350	COG1994	Peptidase M50
H9401_RS27360	COG1078	dGTPase activity
H9401_RS27365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9401_RS27370	COG1120	ATPase activity
H9401_RS27375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS27380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS27385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9401_RS27405	COG0095	Lipoate-protein ligase
H9401_RS27410	COG0280	phosphate acetyltransferase
H9401_RS27425	COG3773	Cell wall hydrolase
H9401_RS27435	COG2363	Small membrane protein
H9401_RS27445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9401_RS27450	COG2233	PERMEase
H9401_RS27455	COG0561	phosphatase activity
H9401_RS27460	COG2814	Major facilitator Superfamily
H9401_RS27470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H9401_RS27475	COG1131	(ABC) transporter
H9401_RS27480	COG2755	lipolytic protein G-D-S-L family
H9401_RS27485	COG1609	Transcriptional regulator
H9401_RS27505	COG2873	o-acetylhomoserine
H9401_RS27515	COG1011	Hydrolase
H9401_RS27520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9401_RS27530	COG2197	response regulator
H9401_RS27540	COG0351	phosphomethylpyrimidine kinase
H9401_RS27545	COG3706	GGDEF domain
H9401_RS27550	COG2879	small protein
H9401_RS27555	COG1966	Carbon starvation protein
H9401_RS27560	COG3279	Response regulator of the LytR AlgR family
H9401_RS27565	COG0477	Major facilitator Superfamily
H9401_RS27590	COG0840	transmembrane signaling receptor activity
H9401_RS27600	COG1607	acyl-coa hydrolase
H9401_RS27615	COG0488	(ABC) transporter
H9401_RS27640	COG0463	Glycosyl transferase, family 2
H9401_RS27645	COG1309	transcriptional regulator
H9401_RS27650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9401_RS27655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9401_RS27655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9401_RS27660	COG0628	permease
H9401_RS27675	COG3279	Response regulator of the LytR AlgR family
H9401_RS27680	COG3275	phosphorelay sensor kinase activity
H9401_RS27685	COG2814	Major facilitator Superfamily
H9401_RS27690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9401_RS27695	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H9401_RS27700	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9401_RS27720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9401_RS27725	COG1272	protein, Hemolysin III
H9401_RS27745	COG0516	GMP reductase activity
H9401_RS27750	COG1164	Oligoendopeptidase f
H9401_RS27770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9401_RS27775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9401_RS27780	COG4853	Protein conserved in bacteria
H9401_RS27785	COG4863	YycH protein
H9401_RS27790	COG5002	protein histidine kinase activity
H9401_RS27795	COG0745	RESPONSE REGULATOR receiver
H9401_RS27825	COG0305	Participates in initiation and elongation during chromosome replication
H9401_RS27835	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H9401_RS27840	COG4241	membrane
H9401_RS27850	COG0629	single-stranded DNA binding
H9401_RS27860	COG0012	GTP binding
H9401_RS27865	COG4481	Protein conserved in bacteria
H9401_RS27870	COG0668	transmembrane transport
H9401_RS27880	COG1475	DNA binding
H9401_RS27885	COG1192	Involved in chromosome partitioning
H9401_RS27910	COG1847	R3H domain protein
H9401_RS27915	COG0706	membrane insertase activity
H9401_RS27925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9401_RS28220	COG2208	phosphoserine phosphatase activity
H9401_RS28365	COG4956	integral membrane protein (PIN domain superfamily)
H9401_RS28550	COG0024	Methionine aminopeptidase
H9401_RS28630	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H9401_RS28750	COG2011	ABC-type metal ion transport system permease component
H9401_RS29170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9401_RS29270	COG2376	Dihydroxyacetone kinase