locus-tag	class	description
MI63_RS00010	COG0592	DNA-directed DNA polymerase activity
MI63_RS00015	COG2501	S4 domain
MI63_RS00025	COG0187	DNA topoisomerase II activity
MI63_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MI63_RS00065	COG0517	IMP dehydrogenase activity
MI63_RS00065	COG0516	GMP reductase activity
MI63_RS00070	COG1686	Belongs to the peptidase S11 family
MI63_RS00100	COG1428	Deoxynucleoside kinase
MI63_RS00105	COG1428	Deoxynucleoside kinase
MI63_RS00110	COG1335	isochorismatase
MI63_RS00120	COG0590	tRNA wobble adenosine to inosine editing
MI63_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MI63_RS00180	COG1982	Orn Lys Arg decarboxylase major
MI63_RS00190	COG0470	DNA polymerase III
MI63_RS00195	COG1774	PSP1 C-terminal conserved region
MI63_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MI63_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MI63_RS00220	COG2002	toxin-antitoxin pair type II binding
MI63_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MI63_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MI63_RS00230	COG0084	hydrolase, TatD family'
MI63_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MI63_RS00250	COG4466	Protein conserved in bacteria
MI63_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MI63_RS00270	COG0251	oxidation-reduction process
MI63_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MI63_RS00305	COG2002	toxin-antitoxin pair type II binding
MI63_RS00310	COG2244	polysaccharide biosynthetic process
MI63_RS00315	COG3956	TIGRFAM MazG family protein
MI63_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MI63_RS00340	COG1098	S1 RNA binding domain
MI63_RS00355	COG2208	phosphoserine phosphatase activity
MI63_RS00360	COG0037	tRNA processing
MI63_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MI63_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MI63_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MI63_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MI63_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
MI63_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MI63_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MI63_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MI63_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MI63_RS00420	COG1396	sequence-specific DNA binding
MI63_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MI63_RS00455	COG3880	PFAM UvrB UvrC protein
MI63_RS00465	COG0542	response to heat
MI63_RS00470	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MI63_RS00480	COG4956	integral membrane protein (PIN domain superfamily)
MI63_RS00500	COG1045	serine acetyltransferase
MI63_RS00515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MI63_RS00520	COG3688	RNA-binding protein containing a PIN domain
MI63_RS00535	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MI63_RS00540	COG0250	Participates in transcription elongation, termination and antitermination
MI63_RS00545	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MI63_RS00565	COG2813	Specifically methylates the guanine in position
MI63_RS00575	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MI63_RS00580	COG1358	cellular component organization or biogenesis
MI63_RS00650	COG0255	Belongs to the universal ribosomal protein uL29 family
MI63_RS00710	COG0201	protein transport
MI63_RS00720	COG0024	Methionine aminopeptidase
MI63_RS00730	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MI63_RS00765	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MI63_RS00790	COG0860	N-Acetylmuramoyl-L-alanine amidase
MI63_RS00795	COG0489	protein tyrosine kinase activity
MI63_RS00805	COG2194	sulfuric ester hydrolase activity
MI63_RS00810	COG0726	polysaccharide deacetylase
MI63_RS00895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MI63_RS00900	COG4856	YbbR-like protein
MI63_RS00915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MI63_RS00920	COG0596	Alpha beta hydrolase
MI63_RS00940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MI63_RS00945	COG1506	peptidase
MI63_RS00945	COG0823	Involved in the tonB-independent uptake of proteins
MI63_RS00945	COG4946	Tricorn protease homolog
MI63_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS00980	COG2011	ABC-type metal ion transport system permease component
MI63_RS00985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MI63_RS00990	COG1464	Belongs to the NlpA lipoprotein family
MI63_RS00995	COG0604	alcohol dehydrogenase
MI63_RS01010	COG2271	Major facilitator Superfamily
MI63_RS01020	COG2814	Major facilitator Superfamily
MI63_RS01035	COG0601	transmembrane transport
MI63_RS01040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MI63_RS01045	COG0444	Belongs to the ABC transporter superfamily
MI63_RS01050	COG4608	Belongs to the ABC transporter superfamily
MI63_RS01055	COG4166	transmembrane transport
MI63_RS01065	COG2207	Transcriptional regulator
MI63_RS01080	COG4166	transmembrane transport
MI63_RS01085	COG4166	transmembrane transport
MI63_RS01090	COG0656	L-ascorbic acid biosynthetic process
MI63_RS01095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MI63_RS01115	COG4149	molybdate abc transporter
MI63_RS01120	COG0725	ABC transporter, periplasmic molybdate-binding protein
MI63_RS01125	COG1910	domain protein
MI63_RS01140	COG0583	DNA-binding transcription factor activity
MI63_RS01145	COG0697	spore germination
MI63_RS01155	COG0204	Acyl-transferase
MI63_RS01165	COG1609	Transcriptional regulator
MI63_RS01175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS01190	COG0084	hydrolase, TatD family'
MI63_RS01195	COG5298	Protein conserved in bacteria
MI63_RS01220	COG0488	(ABC) transporter
MI63_RS01235	COG0747	negative chemotaxis
MI63_RS01240	COG0601	transmembrane transport
MI63_RS01245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MI63_RS01250	COG0444	Belongs to the ABC transporter superfamily
MI63_RS01255	COG4608	Belongs to the ABC transporter superfamily
MI63_RS01285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MI63_RS01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
MI63_RS01300	COG2814	Major facilitator Superfamily
MI63_RS01315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MI63_RS01325	COG4294	response to UV
MI63_RS01330	COG0457	Tetratricopeptide repeat
MI63_RS01330	COG0705	Rhomboid family
MI63_RS01340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MI63_RS01345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MI63_RS01350	COG0864	Transcriptional regulator
MI63_RS01355	COG2337	Toxic component of a toxin-antitoxin (TA) module
MI63_RS01360	COG2183	response to ionizing radiation
MI63_RS01455	COG0802	atpase or kinase
MI63_RS01460	COG1214	PFAM Peptidase M22, glycoprotease
MI63_RS01465	COG0456	acetyltransferase
MI63_RS01475	COG0488	(ABC) transporter
MI63_RS01490	COG1266	CAAX protease self-immunity
MI63_RS01510	COG2252	PERMEase
MI63_RS01520	COG5002	protein histidine kinase activity
MI63_RS01540	COG1968	undecaprenyl-diphosphatase activity
MI63_RS01555	COG2205	protein histidine kinase activity
MI63_RS01560	COG0745	RESPONSE REGULATOR receiver
MI63_RS01580	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MI63_RS01585	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MI63_RS01590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MI63_RS01600	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MI63_RS01615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MI63_RS01625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MI63_RS01635	COG0151	Belongs to the GarS family
MI63_RS01660	COG0210	DNA helicase
MI63_RS01670	COG4851	CamS sex pheromone cAM373 precursor
MI63_RS01690	COG1335	isochorismatase
MI63_RS01695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MI63_RS01700	COG2011	ABC-type metal ion transport system permease component
MI63_RS01705	COG1464	Belongs to the NlpA lipoprotein family
MI63_RS01725	COG1846	Transcriptional regulator
MI63_RS01750	COG1597	lipid kinase activity
MI63_RS01755	COG0546	phosphoglycolate phosphatase activity
MI63_RS01760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MI63_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS01775	COG2076	Multidrug Resistance protein
MI63_RS01780	COG2309	aminopeptidase activity
MI63_RS01795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS01800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MI63_RS01805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MI63_RS01815	COG4807	Protein conserved in bacteria
MI63_RS01840	COG1757	Na H antiporter
MI63_RS01845	COG1473	amidohydrolase
MI63_RS01860	COG0450	alkyl hydroperoxide reductase
MI63_RS01880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS01885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS01890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS01910	COG0166	Belongs to the GPI family
MI63_RS01945	COG5002	protein histidine kinase activity
MI63_RS01965	COG3541	Predicted nucleotidyltransferase
MI63_RS01970	COG2814	Major facilitator Superfamily
MI63_RS01975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MI63_RS01975	COG0723	plastoquinol--plastocyanin reductase activity
MI63_RS01985	COG0765	amino acid transport
MI63_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MI63_RS02005	COG0840	transmembrane signaling receptor activity
MI63_RS02010	COG0840	transmembrane signaling receptor activity
MI63_RS02015	COG0366	Alpha amylase catalytic
MI63_RS02020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MI63_RS02020	COG2190	(PTS) system
MI63_RS02020	COG1263	PTS System
MI63_RS02050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MI63_RS02065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MI63_RS02075	COG1116	anion transmembrane transporter activity
MI63_RS02080	COG0488	(ABC) transporter
MI63_RS02125	COG2270	Major facilitator Superfamily
MI63_RS02140	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MI63_RS02155	COG2310	stress, protein
MI63_RS02160	COG2310	stress, protein
MI63_RS02165	COG2310	stress, protein
MI63_RS02170	COG0861	Integral membrane protein TerC family
MI63_RS02180	COG3853	Toxic anion resistance protein (TelA)
MI63_RS02195	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MI63_RS02205	COG1295	ribonuclease BN
MI63_RS02210	COG2217	Heavy metal translocating P-type atpase
MI63_RS02215	COG0697	spore germination
MI63_RS02235	COG0586	Pfam SNARE associated Golgi protein
MI63_RS02250	COG3871	stress protein (general stress protein 26)
MI63_RS02255	COG0387	Pfam Sodium calcium exchanger
MI63_RS02265	COG0535	radical SAM domain protein
MI63_RS02290	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MI63_RS02295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MI63_RS02300	COG0582	viral genome integration into host DNA
MI63_RS02305	COG1396	sequence-specific DNA binding
MI63_RS02320	COG1396	sequence-specific DNA binding
MI63_RS02355	COG1484	DNA-dependent DNA replication
MI63_RS02450	COG0582	viral genome integration into host DNA
MI63_RS02455	COG0582	viral genome integration into host DNA
MI63_RS02575	COG0101	tRNA pseudouridine synthase activity
MI63_RS02585	COG3829	transcription factor binding
MI63_RS02595	COG0833	amino acid
MI63_RS02600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MI63_RS02635	COG1263	PTS System
MI63_RS02635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MI63_RS02640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MI63_RS02655	COG0463	Glycosyl transferase, family 2
MI63_RS02670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MI63_RS02670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MI63_RS02690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MI63_RS02710	COG1228	amidohydrolase
MI63_RS02715	COG1090	epimerase
MI63_RS02745	COG1988	membrane-bound metal-dependent
MI63_RS02750	COG1194	a g-specific adenine glycosylase
MI63_RS02775	COG1132	(ABC) transporter
MI63_RS02780	COG4129	membrane
MI63_RS02785	COG0069	glutamate synthase activity
MI63_RS02785	COG0067	glutamate synthase
MI63_RS02785	COG0070	glutamate synthase
MI63_RS02795	COG4555	ABC transporter
MI63_RS02815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MI63_RS02820	COG0735	belongs to the Fur family
MI63_RS02935	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MI63_RS02940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MI63_RS02950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MI63_RS02960	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MI63_RS02975	COG2766	serine protein kinase
MI63_RS03000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MI63_RS03010	COG1585	Membrane protein implicated in regulation of membrane protease activity
MI63_RS03015	COG2268	Band 7 protein
MI63_RS03025	COG3290	protein histidine kinase activity
MI63_RS03030	COG4565	transcriptional regulatory protein
MI63_RS03035	COG2851	Citrate transporter
MI63_RS03055	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MI63_RS03060	COG3842	ATPase activity
MI63_RS03065	COG1175	transmembrane transport
MI63_RS03070	COG0395	ABC-type sugar transport system, permease component
MI63_RS03080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MI63_RS03085	COG0745	RESPONSE REGULATOR receiver
MI63_RS03090	COG5002	protein histidine kinase activity
MI63_RS03100	COG4990	cell redox homeostasis
MI63_RS03110	COG3290	protein histidine kinase activity
MI63_RS03115	COG4565	transcriptional regulatory protein
MI63_RS03120	COG3493	citrate carrier protein
MI63_RS03125	COG0281	malic enzyme
MI63_RS03140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS03150	COG5002	protein histidine kinase activity
MI63_RS03155	COG0745	RESPONSE REGULATOR receiver
MI63_RS03165	COG0454	-acetyltransferase
MI63_RS03165	COG0456	acetyltransferase
MI63_RS03170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MI63_RS03175	COG3383	formate dehydrogenase (NAD+) activity
MI63_RS03180	COG2427	Protein of unknown function (DUF1641)
MI63_RS03195	COG0531	amino acid
MI63_RS03200	COG0640	Transcriptional regulator
MI63_RS03205	COG2217	Heavy metal translocating P-type atpase
MI63_RS03210	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MI63_RS03220	COG3227	Zinc metalloprotease (Elastase)
MI63_RS03240	COG2720	vancomycin resistance protein
MI63_RS03245	COG1316	TRANSCRIPTIONal
MI63_RS03250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS03255	COG0346	lactoylglutathione lyase activity
MI63_RS03260	COG1253	flavin adenine dinucleotide binding
MI63_RS03265	COG1027	Aspartate ammonia-lyase
MI63_RS03270	COG1620	l-lactate permease
MI63_RS03285	COG3104	oligopeptide transport
MI63_RS03290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS03295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS03300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS03310	COG2226	methyltransferase
MI63_RS03315	COG0156	8-amino-7-oxononanoate synthase activity
MI63_RS03320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MI63_RS03330	COG4548	von Willebrand factor, type A
MI63_RS03335	COG0714	Associated with various cellular activities
MI63_RS03340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MI63_RS03360	COG0531	amino acid
MI63_RS03365	COG2188	Transcriptional regulator
MI63_RS03370	COG1263	PTS System
MI63_RS03370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MI63_RS03375	COG0366	Alpha amylase catalytic
MI63_RS03390	COG0697	spore germination
MI63_RS03400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MI63_RS03405	COG1115	amino acid carrier protein
MI63_RS03410	COG1126	abc transporter atp-binding protein
MI63_RS03415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MI63_RS03420	COG0765	amino acid transport
MI63_RS03425	COG0765	amino acid transport
MI63_RS03430	COG0833	amino acid
MI63_RS03455	COG2378	regulation of single-species biofilm formation
MI63_RS03460	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MI63_RS03465	COG5002	protein histidine kinase activity
MI63_RS03480	COG0659	secondary active sulfate transmembrane transporter activity
MI63_RS03495	COG0747	negative chemotaxis
MI63_RS03505	COG0601	transmembrane transport
MI63_RS03510	COG4608	Belongs to the ABC transporter superfamily
MI63_RS03520	COG2271	Major facilitator Superfamily
MI63_RS03525	COG1846	Transcriptional regulator
MI63_RS03530	COG0477	Major facilitator Superfamily
MI63_RS03535	COG0477	Major facilitator Superfamily
MI63_RS03540	COG1609	Transcriptional regulator
MI63_RS03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MI63_RS03560	COG1172	Belongs to the binding-protein-dependent transport system permease family
MI63_RS03565	COG1879	ABC-type sugar transport system periplasmic component
MI63_RS03590	COG1063	alcohol dehydrogenase
MI63_RS03605	COG3568	Endonuclease Exonuclease Phosphatase
MI63_RS03630	COG1968	undecaprenyl-diphosphatase activity
MI63_RS03635	COG0840	transmembrane signaling receptor activity
MI63_RS03640	COG3584	3D domain protein
MI63_RS03640	COG1388	LysM domain
MI63_RS03645	COG1476	TRANSCRIPTIONal
MI63_RS03660	COG3104	oligopeptide transport
MI63_RS03665	COG1114	Component of the transport system for branched-chain amino acids
MI63_RS03680	COG1113	amino acid transport
MI63_RS03685	COG2252	PERMEase
MI63_RS03710	COG0569	domain protein
MI63_RS03710	COG0475	glutathione-regulated potassium exporter activity
MI63_RS03725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MI63_RS03730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MI63_RS03735	COG0833	amino acid
MI63_RS03740	COG4990	cell redox homeostasis
MI63_RS03755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MI63_RS03760	COG0697	spore germination
MI63_RS03765	COG0531	amino acid
MI63_RS03780	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MI63_RS03785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MI63_RS03790	COG1918	ferrous iron import across plasma membrane
MI63_RS03790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MI63_RS03795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MI63_RS03800	COG0573	inorganic phosphate transmembrane transporter activity
MI63_RS03805	COG0581	inorganic phosphate transmembrane transporter activity
MI63_RS03815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MI63_RS03935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MI63_RS03960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MI63_RS03965	COG1116	anion transmembrane transporter activity
MI63_RS03970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MI63_RS03975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MI63_RS03980	COG0352	thiamine-phosphate diphosphorylase activity
MI63_RS03985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MI63_RS03990	COG2104	thiamine diphosphate biosynthetic process
MI63_RS04000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MI63_RS04005	COG0351	phosphomethylpyrimidine kinase
MI63_RS04050	COG2205	protein histidine kinase activity
MI63_RS04055	COG2814	Major facilitator Superfamily
MI63_RS04060	COG1846	Transcriptional regulator
MI63_RS04075	COG2252	PERMEase
MI63_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS04085	COG1376	ErfK ybiS ycfS ynhG family protein
MI63_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MI63_RS04100	COG1621	beta-fructofuranosidase activity
MI63_RS04105	COG1263	PTS System
MI63_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MI63_RS04110	COG1609	Transcriptional regulator
MI63_RS04120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MI63_RS04160	COG0778	Nitroreductase
MI63_RS04165	COG2719	SpoVR family
MI63_RS04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
MI63_RS04195	COG1937	Protein conserved in bacteria
MI63_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
MI63_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MI63_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MI63_RS04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
MI63_RS04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MI63_RS04225	COG2210	Belongs to the sulfur carrier protein TusA family
MI63_RS04230	COG0730	response to heat
MI63_RS04240	COG1316	TRANSCRIPTIONal
MI63_RS04245	COG0604	alcohol dehydrogenase
MI63_RS04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
MI63_RS04265	COG3711	transcriptional antiterminator
MI63_RS04265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MI63_RS04270	COG1447	Phosphotransferase system cellobiose-specific component IIA
MI63_RS04275	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MI63_RS04295	COG1388	LysM domain
MI63_RS04295	COG3584	3D domain protein
MI63_RS04300	COG0577	efflux transmembrane transporter activity
MI63_RS04305	COG1136	(ABC) transporter
MI63_RS04315	COG5522	Integral membrane protein (intg_mem_TP0381)
MI63_RS04330	COG1114	Component of the transport system for branched-chain amino acids
MI63_RS04335	COG3546	catalase activity
MI63_RS04370	COG0586	Pfam SNARE associated Golgi protein
MI63_RS04405	COG0531	amino acid
MI63_RS04410	COG0475	glutathione-regulated potassium exporter activity
MI63_RS04420	COG1737	Transcriptional regulator
MI63_RS04430	COG1263	PTS System
MI63_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MI63_RS04440	COG2259	Doxx family
MI63_RS04455	COG0697	spore germination
MI63_RS04460	COG1522	sequence-specific DNA binding
MI63_RS04475	COG2076	Multidrug Resistance protein
MI63_RS04480	COG1309	transcriptional regulator
MI63_RS04485	COG2814	Major facilitator Superfamily
MI63_RS04490	COG1733	regulation of RNA biosynthetic process
MI63_RS04500	COG2249	NAD(P)H dehydrogenase (quinone) activity
MI63_RS04505	COG4533	DNA binding
MI63_RS04510	COG2814	Major facilitator Superfamily
MI63_RS04520	COG0693	protein deglycase activity
MI63_RS04525	COG0693	protein deglycase activity
MI63_RS04525	COG0753	catalase activity
MI63_RS04535	COG0531	amino acid
MI63_RS04540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MI63_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS04560	COG1132	(ABC) transporter
MI63_RS04575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MI63_RS04580	COG0765	amino acid transport
MI63_RS04585	COG1126	abc transporter atp-binding protein
MI63_RS04600	COG0189	ligase activity
MI63_RS04630	COG0028	Belongs to the TPP enzyme family
MI63_RS04635	COG3527	Alpha-acetolactate decarboxylase
MI63_RS04650	COG0561	phosphatase activity
MI63_RS04665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MI63_RS04680	COG0659	secondary active sulfate transmembrane transporter activity
MI63_RS04700	COG0653	protein targeting
MI63_RS04705	COG2244	polysaccharide biosynthetic process
MI63_RS04715	COG0860	N-Acetylmuramoyl-L-alanine amidase
MI63_RS04720	COG4196	transglutaminase domain protein
MI63_RS04735	COG1696	Membrane protein involved in D-alanine export
MI63_RS04750	COG1024	Enoyl-CoA hydratase
MI63_RS04770	COG1363	Peptidase, m42
MI63_RS04790	COG3938	Belongs to the proline racemase family
MI63_RS04830	COG0601	transmembrane transport
MI63_RS04835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MI63_RS04845	COG4608	Belongs to the ABC transporter superfamily
MI63_RS04875	COG0477	Major facilitator Superfamily
MI63_RS04880	COG3290	protein histidine kinase activity
MI63_RS04885	COG4565	transcriptional regulatory protein
MI63_RS04890	COG3181	Tripartite tricarboxylate transporter family receptor
MI63_RS04920	COG4978	Transcriptional regulator
MI63_RS04920	COG0789	Transcriptional regulator
MI63_RS04935	COG0305	Participates in initiation and elongation during chromosome replication
MI63_RS04975	COG0477	Major facilitator Superfamily
MI63_RS05030	COG1309	transcriptional regulator
MI63_RS05050	COG1183	phosphatidylcholine synthase activity
MI63_RS05070	COG2376	Dihydroxyacetone kinase
MI63_RS05085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MI63_RS05090	COG1959	2 iron, 2 sulfur cluster binding
MI63_RS05115	COG2770	Histidine kinase
MI63_RS05115	COG3437	response regulator, receiver
MI63_RS05165	COG3237	CsbD-like
MI63_RS05190	COG1191	sigma factor activity
MI63_RS05200	COG2208	phosphoserine phosphatase activity
MI63_RS05205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MI63_RS05210	COG2198	Histidine kinase
MI63_RS05210	COG2205	protein histidine kinase activity
MI63_RS05210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MI63_RS05210	COG0784	Response regulator, receiver
MI63_RS05270	COG0420	3'-5' exonuclease activity
MI63_RS05275	COG4717	serine-type aminopeptidase activity
MI63_RS05295	COG1309	transcriptional regulator
MI63_RS05300	COG2814	Major facilitator Superfamily
MI63_RS05305	COG0346	lactoylglutathione lyase activity
MI63_RS05310	COG0346	lactoylglutathione lyase activity
MI63_RS05315	COG0457	Tetratricopeptide repeat
MI63_RS05320	COG2267	carboxylic ester hydrolase activity
MI63_RS05340	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MI63_RS05345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MI63_RS05355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MI63_RS05395	COG0477	Major facilitator Superfamily
MI63_RS05400	COG0477	Major facilitator Superfamily
MI63_RS05410	COG3973	AAA domain
MI63_RS05415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MI63_RS05440	COG4980	gas vesicle protein
MI63_RS05445	COG0537	adenosine 5'-monophosphoramidase activity
MI63_RS05450	COG1131	(ABC) transporter
MI63_RS05455	COG4473	ABC transporter
MI63_RS05465	COG1309	transcriptional regulator
MI63_RS05475	COG3402	PFAM membrane-flanked domain
MI63_RS05485	COG3428	Bacterial PH domain
MI63_RS05530	COG3402	PFAM membrane-flanked domain
MI63_RS05535	COG3428	Bacterial PH domain
MI63_RS05540	COG2329	Antibiotic biosynthesis monooxygenase
MI63_RS05545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MI63_RS05550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MI63_RS05555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MI63_RS05560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MI63_RS05595	COG1309	transcriptional regulator
MI63_RS05600	COG1511	domain protein
MI63_RS05625	COG1609	Transcriptional regulator
MI63_RS05635	COG1234	tRNA 3'-trailer cleavage
MI63_RS05640	COG0095	Lipoate-protein ligase
MI63_RS05650	COG0318	PFAM AMP-dependent synthetase and ligase
MI63_RS05680	COG3209	COG3209 Rhs family protein
MI63_RS05725	COG1408	metallophosphoesterase
MI63_RS05730	COG1078	dGTPase activity
MI63_RS05740	COG1595	DNA-templated transcription, initiation
MI63_RS05745	COG2207	Transcriptional regulator
MI63_RS05745	COG3708	Transcriptional regulator
MI63_RS05760	COG2205	protein histidine kinase activity
MI63_RS05765	COG0745	RESPONSE REGULATOR receiver
MI63_RS05790	COG0501	Belongs to the peptidase M48B family
MI63_RS05795	COG0840	transmembrane signaling receptor activity
MI63_RS05800	COG0697	spore germination
MI63_RS05820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MI63_RS05825	COG2224	Isocitrate lyase
MI63_RS05850	COG4903	ComK protein
MI63_RS05855	COG0398	Pfam SNARE associated Golgi protein
MI63_RS05865	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MI63_RS05870	COG1074	ATP-dependent DNA helicase activity
MI63_RS05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
MI63_RS05940	COG0367	asparagine synthase
MI63_RS05945	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MI63_RS05950	COG0753	catalase activity
MI63_RS05955	COG0004	ammonium transporteR
MI63_RS05980	COG2996	Protein conserved in bacteria
MI63_RS05990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MI63_RS06000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS06015	COG0561	phosphatase activity
MI63_RS06030	COG0542	response to heat
MI63_RS06040	COG2267	carboxylic ester hydrolase activity
MI63_RS06055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MI63_RS06060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MI63_RS06065	COG5504	Zn-dependent protease
MI63_RS06075	COG0180	Tryptophanyl-tRNA synthetase
MI63_RS06085	COG4166	transmembrane transport
MI63_RS06090	COG0601	transmembrane transport
MI63_RS06095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MI63_RS06100	COG0444	Belongs to the ABC transporter superfamily
MI63_RS06105	COG4608	Belongs to the ABC transporter superfamily
MI63_RS06110	COG0534	Mate efflux family protein
MI63_RS06115	COG4166	transmembrane transport
MI63_RS06135	COG0861	Integral membrane protein TerC family
MI63_RS06140	COG4862	establishment of competence for transformation
MI63_RS06145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MI63_RS06155	COG1164	Oligoendopeptidase f
MI63_RS06165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MI63_RS06170	COG2346	COG2346, Truncated hemoglobins
MI63_RS06175	COG4116	CYTH
MI63_RS06185	COG2357	RelA SpoT domain protein
MI63_RS06195	COG0564	pseudouridine synthase activity
MI63_RS06210	COG0772	Belongs to the SEDS family
MI63_RS06215	COG0463	Glycosyl transferase, family 2
MI63_RS06215	COG1216	Glycosyl transferase, family 2
MI63_RS06235	COG0463	Glycosyl transferase, family 2
MI63_RS06235	COG0457	Tetratricopeptide repeat
MI63_RS06255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MI63_RS06270	COG1091	dTDP-4-dehydrorhamnose reductase activity
MI63_RS06315	COG2153	protein acetylation
MI63_RS06325	COG2382	esterase
MI63_RS06340	COG5492	domain, Protein
MI63_RS06345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MI63_RS06360	COG0512	Glutamine amidotransferase of anthranilate synthase
MI63_RS06360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MI63_RS06395	COG1620	l-lactate permease
MI63_RS06400	COG5634	Uncharacterized conserved protein (DUF2278)
MI63_RS06450	COG0508	dehydrogenase complex catalyzes the overall conversion of
MI63_RS06460	COG1476	TRANSCRIPTIONal
MI63_RS06520	COG2226	methyltransferase
MI63_RS06530	COG1686	Belongs to the peptidase S11 family
MI63_RS06535	COG0681	Belongs to the peptidase S26 family
MI63_RS06570	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS06575	COG3842	ATPase activity
MI63_RS06580	COG1176	ABC-type spermidine putrescine transport system, permease component I
MI63_RS06585	COG1177	transmembrane transport
MI63_RS06590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MI63_RS06600	COG2409	Drug exporters of the RND superfamily
MI63_RS06610	COG0564	pseudouridine synthase activity
MI63_RS06620	COG2340	Cysteine-rich secretory protein family
MI63_RS06625	COG0247	lactate metabolic process
MI63_RS06630	COG0277	FAD linked oxidase domain protein
MI63_RS06635	COG3835	regulator
MI63_RS06645	COG0745	RESPONSE REGULATOR receiver
MI63_RS06650	COG5002	protein histidine kinase activity
MI63_RS06655	COG2186	Transcriptional regulator
MI63_RS06675	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MI63_RS06685	COG2116	formate transmembrane transporter activity
MI63_RS06690	COG0861	Integral membrane protein TerC family
MI63_RS06705	COG2030	dehydratase
MI63_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS06730	COG3243	poly(R)-hydroxyalkanoic acid synthase
MI63_RS06735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MI63_RS06740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MI63_RS06755	COG1840	ABC-type Fe3 transport system, periplasmic component
MI63_RS06785	COG1349	DNA-binding transcription factor activity
MI63_RS06810	COG2861	carbohydrate metabolic process
MI63_RS06820	COG3852	Histidine kinase
MI63_RS06825	COG1846	Transcriptional regulator
MI63_RS06835	COG2318	DinB family
MI63_RS06845	COG5002	protein histidine kinase activity
MI63_RS06855	COG0720	synthase
MI63_RS06870	COG4873	Protein conserved in bacteria
MI63_RS06905	COG1780	Probably involved in ribonucleotide reductase function
MI63_RS06920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MI63_RS06925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MI63_RS06930	COG1725	Transcriptional regulator
MI63_RS06935	COG1131	(ABC) transporter
MI63_RS06945	COG1131	(ABC) transporter
MI63_RS06950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MI63_RS06965	COG1522	sequence-specific DNA binding
MI63_RS06975	COG1335	isochorismatase
MI63_RS06985	COG1619	proteins homologs of microcin C7 resistance protein MccF
MI63_RS06990	COG2070	2-Nitropropane dioxygenase
MI63_RS06995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MI63_RS07005	COG1696	Membrane protein involved in D-alanine export
MI63_RS07030	COG0716	FMN binding
MI63_RS07045	COG3173	Aminoglycoside phosphotransferase
MI63_RS07065	COG0534	Mate efflux family protein
MI63_RS07070	COG1968	undecaprenyl-diphosphatase activity
MI63_RS07085	COG1846	Transcriptional regulator
MI63_RS07095	COG1301	dicarboxylic acid transport
MI63_RS07100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MI63_RS07105	COG4709	membrane
MI63_RS07110	COG3874	Sporulation protein YtfJ
MI63_RS07140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MI63_RS07145	COG0028	Belongs to the TPP enzyme family
MI63_RS07150	COG0440	acetolactate synthase activity
MI63_RS07155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MI63_RS07165	COG0473	3-isopropylmalate dehydrogenase activity
MI63_RS07190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MI63_RS07225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MI63_RS07240	COG1183	phosphatidylcholine synthase activity
MI63_RS07245	COG1368	sulfuric ester hydrolase activity
MI63_RS07255	COG0019	diaminopimelate decarboxylase activity
MI63_RS07275	COG0529	Catalyzes the synthesis of activated sulfate
MI63_RS07280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MI63_RS07300	COG1648	precorrin-2 dehydrogenase activity
MI63_RS07310	COG0733	neurotransmitter:sodium symporter activity
MI63_RS07330	COG1757	Na H antiporter
MI63_RS07345	COG4758	membrane
MI63_RS07350	COG4585	Histidine kinase
MI63_RS07355	COG2197	response regulator
MI63_RS07365	COG1114	Component of the transport system for branched-chain amino acids
MI63_RS07375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MI63_RS07400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MI63_RS07400	COG1017	nitric oxide dioxygenase activity
MI63_RS07420	COG0730	response to heat
MI63_RS07425	COG0306	phosphate transporter
MI63_RS07430	COG1392	Phosphate transport regulator
MI63_RS07435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MI63_RS07450	COG3852	Histidine kinase
MI63_RS07455	COG1801	Protein of unknown function DUF72
MI63_RS07465	COG0582	viral genome integration into host DNA
MI63_RS07470	COG5002	protein histidine kinase activity
MI63_RS07490	COG0392	lysyltransferase activity
MI63_RS07490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MI63_RS07505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MI63_RS07510	COG1686	Belongs to the peptidase S11 family
MI63_RS07515	COG2715	membrane protein required for spore maturation
MI63_RS07520	COG0700	Nucleoside recognition
MI63_RS07525	COG1187	pseudouridine synthase activity
MI63_RS07535	COG1333	cytochrome c biogenesis protein
MI63_RS07540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MI63_RS07545	COG0745	RESPONSE REGULATOR receiver
MI63_RS07550	COG5002	protein histidine kinase activity
MI63_RS07555	COG2096	Adenosyltransferase
MI63_RS07570	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MI63_RS07575	COG1141	Ferredoxin
MI63_RS07580	COG4955	Helix-turn-helix domain
MI63_RS07585	COG0514	ATP-dependent DNA helicase (RecQ)
MI63_RS07590	COG1266	CAAX protease self-immunity
MI63_RS07610	COG4862	establishment of competence for transformation
MI63_RS07615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MI63_RS07635	COG0492	ferredoxin-NADP+ reductase activity
MI63_RS07640	COG0252	asparaginase activity
MI63_RS07710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MI63_RS07725	COG0142	geranyltranstransferase activity
MI63_RS07735	COG0142	geranyltranstransferase activity
MI63_RS07755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MI63_RS07760	COG0457	Tetratricopeptide repeat
MI63_RS07780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MI63_RS07790	COG4347	Protein of unknown function (DUF1405)
MI63_RS07805	COG2738	Putative neutral zinc metallopeptidase
MI63_RS07815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS07820	COG1694	Mazg nucleotide pyrophosphohydrolase
MI63_RS07835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MI63_RS07840	COG0438	transferase activity, transferring glycosyl groups
MI63_RS07900	COG3935	DnaD domain protein
MI63_RS07905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MI63_RS07915	COG4499	WXG100 protein secretion system (Wss), protein YukC
MI63_RS07915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MI63_RS07965	COG0116	Belongs to the methyltransferase superfamily
MI63_RS07975	COG1199	ATP-dependent helicase activity
MI63_RS07980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MI63_RS07990	COG3173	Aminoglycoside phosphotransferase
MI63_RS07995	COG0024	Methionine aminopeptidase
MI63_RS08005	COG2233	PERMEase
MI63_RS08010	COG2311	Membrane
MI63_RS08015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MI63_RS08025	COG0456	acetyltransferase
MI63_RS08050	COG0754	glutathionylspermidine amidase activity
MI63_RS08065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MI63_RS08090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MI63_RS08105	COG1215	transferase activity, transferring glycosyl groups
MI63_RS08125	COG0454	-acetyltransferase
MI63_RS08150	COG0328	RNA-DNA hybrid ribonuclease activity
MI63_RS08190	COG1280	lysine exporter protein (LysE YggA)
MI63_RS08205	COG3162	membrane
MI63_RS08210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MI63_RS08215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MI63_RS08225	COG0475	glutathione-regulated potassium exporter activity
MI63_RS08230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MI63_RS08235	COG0789	Transcriptional regulator
MI63_RS08235	COG4978	Transcriptional regulator
MI63_RS08245	COG2323	membrane
MI63_RS08250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MI63_RS08305	COG1923	regulation of RNA biosynthetic process
MI63_RS08315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MI63_RS08320	COG1360	Flagellar Motor Protein
MI63_RS08325	COG2201	protein-glutamate methylesterase activity
MI63_RS08335	COG1776	CheC inhibitor of MCP methylation
MI63_RS08335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MI63_RS08350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MI63_RS08370	COG1256	bacterial-type flagellum assembly
MI63_RS08375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MI63_RS08400	COG1815	bacterial-type flagellum-dependent cell motility
MI63_RS08405	COG1558	bacterial-type flagellum-dependent cell motility
MI63_RS08415	COG1766	The M ring may be actively involved in energy transduction
MI63_RS08425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MI63_RS08435	COG1157	protein secretion by the type III secretion system
MI63_RS08475	COG0835	chemotaxis
MI63_RS08475	COG0784	Response regulator, receiver
MI63_RS08485	COG0463	Glycosyl transferase, family 2
MI63_RS08515	COG0457	Tetratricopeptide repeat
MI63_RS08515	COG0463	Glycosyl transferase, family 2
MI63_RS08540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MI63_RS08545	COG0741	lytic transglycosylase activity
MI63_RS08560	COG1776	CheC inhibitor of MCP methylation
MI63_RS08560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MI63_RS08570	COG1338	Plays a role in the flagellum-specific transport system
MI63_RS08575	COG1987	bacterial-type flagellum assembly
MI63_RS08585	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MI63_RS08590	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MI63_RS08600	COG4786	Flagellar basal body rod
MI63_RS08605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MI63_RS08630	COG1309	transcriptional regulator
MI63_RS08650	COG2329	Antibiotic biosynthesis monooxygenase
MI63_RS08680	COG3842	ATPase activity
MI63_RS08685	COG0725	ABC transporter, periplasmic molybdate-binding protein
MI63_RS08695	COG1234	tRNA 3'-trailer cleavage
MI63_RS08720	COG1686	Belongs to the peptidase S11 family
MI63_RS08760	COG0367	asparagine synthase
MI63_RS08790	COG1802	Transcriptional regulator
MI63_RS08795	COG0697	spore germination
MI63_RS08800	COG0523	cobalamin synthesis protein
MI63_RS08805	COG0701	Predicted permease
MI63_RS08815	COG0438	transferase activity, transferring glycosyl groups
MI63_RS08815	COG1216	Glycosyl transferase, family 2
MI63_RS08820	COG1757	Na H antiporter
MI63_RS08825	COG0114	fumarate hydratase activity
MI63_RS08855	COG3340	Belongs to the peptidase S51 family
MI63_RS08875	COG0785	Cytochrome C biogenesis protein
MI63_RS08910	COG2733	membrane
MI63_RS08945	COG1131	(ABC) transporter
MI63_RS08960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MI63_RS08965	COG0528	UMP kinase activity
MI63_RS08980	COG0281	malic enzyme
MI63_RS08985	COG4191	Histidine kinase
MI63_RS08990	COG0784	Response regulator, receiver
MI63_RS08995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MI63_RS09060	COG0860	N-Acetylmuramoyl-L-alanine amidase
MI63_RS09070	COG2814	Major facilitator Superfamily
MI63_RS09085	COG1966	Carbon starvation protein
MI63_RS09095	COG0477	Major facilitator Superfamily
MI63_RS09100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MI63_RS09110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MI63_RS09140	COG2244	polysaccharide biosynthetic process
MI63_RS09145	COG0733	neurotransmitter:sodium symporter activity
MI63_RS09155	COG5566	PFAM Mor transcription activator
MI63_RS09160	COG2323	membrane
MI63_RS09175	COG2084	Dehydrogenase
MI63_RS09190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MI63_RS09200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MI63_RS09205	COG0028	Belongs to the TPP enzyme family
MI63_RS09210	COG0440	acetolactate synthase activity
MI63_RS09215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MI63_RS09225	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MI63_RS09255	COG3384	dioxygenase
MI63_RS09265	COG3279	Response regulator of the LytR AlgR family
MI63_RS09270	COG0427	acetyl-CoA hydrolase
MI63_RS09290	COG1073	alpha beta
MI63_RS09295	COG4166	transmembrane transport
MI63_RS09320	COG0535	radical SAM domain protein
MI63_RS09325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS09345	COG1914	H( )-stimulated, divalent metal cation uptake system
MI63_RS09360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MI63_RS09395	COG2390	Transcriptional regulator
MI63_RS09405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS09410	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MI63_RS09425	COG4224	UPF0291 protein
MI63_RS09445	COG0006	proline dipeptidase activity
MI63_RS09450	COG2132	Multicopper oxidase
MI63_RS09465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MI63_RS09480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MI63_RS09495	COG2372	response to copper ion
MI63_RS09495	COG1276	copper resistance
MI63_RS09500	COG4549	nuclear export factor GLE1
MI63_RS09510	COG0697	spore germination
MI63_RS09515	COG0583	DNA-binding transcription factor activity
MI63_RS09520	COG1959	2 iron, 2 sulfur cluster binding
MI63_RS09525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MI63_RS09530	COG0778	Nitroreductase
MI63_RS09545	COG0628	permease
MI63_RS09555	COG1231	oxidoreductase activity
MI63_RS09560	COG0523	cobalamin synthesis protein
MI63_RS09575	COG0318	PFAM AMP-dependent synthetase and ligase
MI63_RS09580	COG2030	dehydratase
MI63_RS09585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MI63_RS09595	COG0411	ABC transporter
MI63_RS09615	COG0583	DNA-binding transcription factor activity
MI63_RS09625	COG1942	4-Oxalocrotonate Tautomerase
MI63_RS09635	COG1846	Transcriptional regulator
MI63_RS09645	COG1271	oxidase subunit
MI63_RS09650	COG1294	oxidase, subunit
MI63_RS09655	COG4988	ABC transporter
MI63_RS09660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MI63_RS09680	COG1686	Belongs to the peptidase S11 family
MI63_RS09695	COG0791	NLP P60 protein
MI63_RS09695	COG1388	LysM domain
MI63_RS09705	COG1132	(ABC) transporter
MI63_RS09710	COG1132	(ABC) transporter
MI63_RS09715	COG0745	RESPONSE REGULATOR receiver
MI63_RS09730	COG0300	oxidoreductase activity
MI63_RS09765	COG0460	homoserine dehydrogenase
MI63_RS09790	COG1316	TRANSCRIPTIONal
MI63_RS09800	COG0745	RESPONSE REGULATOR receiver
MI63_RS09805	COG5002	protein histidine kinase activity
MI63_RS09820	COG1285	pathogenesis
MI63_RS09825	COG1247	-acetyltransferase
MI63_RS09845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MI63_RS09855	COG1082	Xylose isomerase domain protein TIM barrel
MI63_RS09865	COG2814	Major facilitator Superfamily
MI63_RS09870	COG1279	arginine transmembrane transporter activity
MI63_RS09880	COG1752	Esterase of the alpha-beta hydrolase superfamily
MI63_RS09915	COG0577	efflux transmembrane transporter activity
MI63_RS09920	COG2002	toxin-antitoxin pair type II binding
MI63_RS09925	COG1404	Belongs to the peptidase S8 family
MI63_RS09930	COG0640	Transcriptional regulator
MI63_RS09935	COG0667	Aldo Keto reductase
MI63_RS09940	COG2814	Major facilitator Superfamily
MI63_RS09965	COG0840	transmembrane signaling receptor activity
MI63_RS09985	COG3949	Membrane
MI63_RS09990	COG0783	Belongs to the Dps family
MI63_RS10005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MI63_RS10015	COG1231	oxidoreductase activity
MI63_RS10025	COG4989	oxidoreductase activity
MI63_RS10030	COG0523	cobalamin synthesis protein
MI63_RS10035	COG0456	acetyltransferase
MI63_RS10100	COG3443	Belongs to the bacterial solute-binding protein 9 family
MI63_RS10100	COG0803	Belongs to the bacterial solute-binding protein 9 family
MI63_RS10110	COG0702	epimerase
MI63_RS10120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MI63_RS10130	COG4166	transmembrane transport
MI63_RS10145	COG0406	alpha-ribazole phosphatase activity
MI63_RS10155	COG5337	Spore coat protein CotH
MI63_RS10160	COG1051	belongs to the nudix hydrolase family
MI63_RS10165	COG0586	Pfam SNARE associated Golgi protein
MI63_RS10170	COG2244	polysaccharide biosynthetic process
MI63_RS10180	COG0701	Predicted permease
MI63_RS10185	COG3689	TIGRFAM TIGR03943 family protein
MI63_RS10190	COG1607	acyl-coa hydrolase
MI63_RS10195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MI63_RS10210	COG0702	epimerase
MI63_RS10215	COG2839	Protein conserved in bacteria
MI63_RS10220	COG1253	flavin adenine dinucleotide binding
MI63_RS10235	COG1114	Component of the transport system for branched-chain amino acids
MI63_RS10240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MI63_RS10260	COG0860	N-Acetylmuramoyl-L-alanine amidase
MI63_RS10270	COG1876	peptidase activity
MI63_RS10280	COG0154	amidase activity
MI63_RS10285	COG2211	Major facilitator Superfamily
MI63_RS10305	COG0561	phosphatase activity
MI63_RS10315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MI63_RS10320	COG4106	trans-aconitate 2-methyltransferase activity
MI63_RS10335	COG1819	glycosyl
MI63_RS10340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS10345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS10370	COG0456	acetyltransferase
MI63_RS10420	COG3874	Sporulation protein YtfJ
MI63_RS10465	COG1082	Xylose isomerase domain protein TIM barrel
MI63_RS10470	COG0346	lactoylglutathione lyase activity
MI63_RS10480	COG0604	alcohol dehydrogenase
MI63_RS10485	COG1595	DNA-templated transcription, initiation
MI63_RS10510	COG0386	Belongs to the glutathione peroxidase family
MI63_RS10515	COG1305	Transglutaminase-like
MI63_RS10520	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MI63_RS10525	COG0714	Associated with various cellular activities
MI63_RS10540	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MI63_RS10545	COG1140	nitrate reductase beta subunit
MI63_RS10550	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MI63_RS10555	COG2181	nitrate reductase activity
MI63_RS10575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MI63_RS10580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MI63_RS10585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MI63_RS10590	COG0303	'Molybdopterin
MI63_RS10595	COG0314	molybdopterin synthase activity
MI63_RS10605	COG2223	nitrite transmembrane transporter activity
MI63_RS10620	COG1648	precorrin-2 dehydrogenase activity
MI63_RS10630	COG1587	Uroporphyrinogen-III synthase
MI63_RS10630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MI63_RS10635	COG2146	nitrite reductase [NAD(P)H] activity
MI63_RS10640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MI63_RS10645	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MI63_RS10680	COG2359	stage V sporulation protein S
MI63_RS10695	COG5632	N-Acetylmuramoyl-L-alanine amidase
MI63_RS10710	COG1418	mRNA catabolic process
MI63_RS10715	COG0488	(ABC) transporter
MI63_RS10730	COG0629	single-stranded DNA binding
MI63_RS10745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MI63_RS10750	COG1413	lyase activity
MI63_RS10765	COG2521	methyltransferase
MI63_RS10765	COG2136	Putative SAM-dependent methyltransferase
MI63_RS10770	COG0018	arginyl-trna synthetase
MI63_RS10795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MI63_RS10810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MI63_RS10815	COG0017	Asparaginyl-tRNA synthetase
MI63_RS10835	COG1674	ftsk spoiiie
MI63_RS10930	COG1929	Belongs to the glycerate kinase type-1 family
MI63_RS10935	COG0471	metal ion transport
MI63_RS10940	COG0745	RESPONSE REGULATOR receiver
MI63_RS10945	COG5002	protein histidine kinase activity
MI63_RS10945	COG3850	Histidine kinase
MI63_RS10960	COG0733	neurotransmitter:sodium symporter activity
MI63_RS10985	COG2610	gluconate transmembrane transporter activity
MI63_RS10990	COG1454	alcohol dehydrogenase
MI63_RS10995	COG1794	racemase activity, acting on amino acids and derivatives
MI63_RS11005	COG0456	acetyltransferase
MI63_RS11020	COG1131	(ABC) transporter
MI63_RS11025	COG4473	ABC transporter
MI63_RS11035	COG0546	phosphoglycolate phosphatase activity
MI63_RS11055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MI63_RS11070	COG0768	penicillin binding
MI63_RS11075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MI63_RS11080	COG0204	Acyl-transferase
MI63_RS11085	COG1272	protein, Hemolysin III
MI63_RS11095	COG0805	protein transport
MI63_RS11105	COG1307	EDD domain protein, DegV family
MI63_RS11110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MI63_RS11115	COG1999	signal sequence binding
MI63_RS11120	COG0071	Belongs to the small heat shock protein (HSP20) family
MI63_RS11125	COG0367	asparagine synthase
MI63_RS11140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS11145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MI63_RS11180	COG0668	transmembrane transport
MI63_RS11185	COG4585	Histidine kinase
MI63_RS11185	COG2203	Gaf domain
MI63_RS11190	COG2197	response regulator
MI63_RS11200	COG1737	Transcriptional regulator
MI63_RS11205	COG1064	alcohol dehydrogenase
MI63_RS11235	COG1070	Carbohydrate kinase
MI63_RS11240	COG1070	Carbohydrate kinase
MI63_RS11270	COG1125	glycine betaine transport
MI63_RS11270	COG0517	IMP dehydrogenase activity
MI63_RS11275	COG1174	glycine betaine transport
MI63_RS11310	COG1253	flavin adenine dinucleotide binding
MI63_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS11320	COG5506	Protein of unknown function (DUF1694)
MI63_RS11335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MI63_RS11340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MI63_RS11345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MI63_RS11350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MI63_RS11355	COG0456	acetyltransferase
MI63_RS11360	COG3829	transcription factor binding
MI63_RS11365	COG1509	lysine 2,3-aminomutase activity
MI63_RS11405	COG4326	sporulation control protein
MI63_RS11410	COG0671	phosphoesterase, PA-phosphatase related
MI63_RS11415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MI63_RS11420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MI63_RS11450	COG1787	Restriction endonuclease
MI63_RS11450	COG1715	Restriction endonuclease
MI63_RS11540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MI63_RS11580	COG4499	WXG100 protein secretion system (Wss), protein YukC
MI63_RS11580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MI63_RS11585	COG2814	Major facilitator Superfamily
MI63_RS11590	COG4841	protein insertion into membrane
MI63_RS11595	COG0372	Belongs to the citrate synthase family
MI63_RS11600	COG2079	MmgE PrpD family protein
MI63_RS11605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MI63_RS11610	COG1960	acyl-CoA dehydrogenase activity
MI63_RS11615	COG2084	Dehydrogenase
MI63_RS11625	COG1280	lysine exporter protein (LysE YggA)
MI63_RS11630	COG1024	Enoyl-CoA hydratase
MI63_RS11645	COG0420	3'-5' exonuclease activity
MI63_RS11650	COG0419	ATPase involved in DNA repair
MI63_RS11680	COG2223	nitrite transmembrane transporter activity
MI63_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS11690	COG1169	isochorismate synthase
MI63_RS11695	COG1021	2,3-dihydroxybenzoate-AMP ligase
MI63_RS11700	COG3433	isochorismatase activity
MI63_RS11700	COG1535	isochorismatase
MI63_RS11710	COG3251	PFAM MbtH domain protein
MI63_RS11715	COG2814	Major facilitator Superfamily
MI63_RS11730	COG0776	regulation of translation
MI63_RS11740	COG2318	DinB family
MI63_RS11770	COG2329	Antibiotic biosynthesis monooxygenase
MI63_RS11775	COG1187	pseudouridine synthase activity
MI63_RS11780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MI63_RS11795	COG0596	Alpha beta hydrolase
MI63_RS11800	COG2814	Major facilitator Superfamily
MI63_RS11820	COG2226	methyltransferase
MI63_RS11865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS11900	COG1247	-acetyltransferase
MI63_RS11930	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MI63_RS11940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS11950	COG1278	Cold shock
MI63_RS11965	COG0010	Belongs to the arginase family
MI63_RS11970	COG0561	phosphatase activity
MI63_RS12015	COG0583	DNA-binding transcription factor activity
MI63_RS12020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MI63_RS12035	COG0583	DNA-binding transcription factor activity
MI63_RS12040	COG2258	MOSC domain
MI63_RS12055	COG1132	(ABC) transporter
MI63_RS12060	COG1132	(ABC) transporter
MI63_RS12080	COG1396	sequence-specific DNA binding
MI63_RS12105	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
MI63_RS12110	COG1595	DNA-templated transcription, initiation
MI63_RS12135	COG1649	PFAM Uncharacterised BCR, COG1649
MI63_RS12160	COG2971	BadF BadG BcrA BcrD
MI63_RS12165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MI63_RS12170	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MI63_RS12190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS12220	COG1309	transcriptional regulator
MI63_RS12240	COG0577	efflux transmembrane transporter activity
MI63_RS12240	COG1136	(ABC) transporter
MI63_RS12245	COG0500	methyltransferase
MI63_RS12245	COG3615	Tellurite resistance protein tehB
MI63_RS12255	COG2226	methyltransferase
MI63_RS12260	COG3961	Belongs to the TPP enzyme family
MI63_RS12265	COG1846	Transcriptional regulator
MI63_RS12305	COG2195	Cleaves the N-terminal amino acid of tripeptides
MI63_RS12320	COG1595	DNA-templated transcription, initiation
MI63_RS12330	COG0768	penicillin binding
MI63_RS12335	COG0768	penicillin binding
MI63_RS12340	COG2367	Beta-lactamase
MI63_RS12345	COG0671	phosphoesterase, PA-phosphatase related
MI63_RS12350	COG1609	Transcriptional regulator
MI63_RS12355	COG2814	Major facilitator Superfamily
MI63_RS12360	COG0673	inositol 2-dehydrogenase activity
MI63_RS12370	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS12385	COG0191	fructose-bisphosphate aldolase activity
MI63_RS12405	COG0737	Belongs to the 5'-nucleotidase family
MI63_RS12420	COG1476	TRANSCRIPTIONal
MI63_RS12435	COG1876	peptidase activity
MI63_RS12455	COG1309	transcriptional regulator
MI63_RS12460	COG0488	(ABC) transporter
MI63_RS12475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS12490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MI63_RS12505	COG1131	(ABC) transporter
MI63_RS12515	COG1309	transcriptional regulator
MI63_RS12530	COG1960	acyl-CoA dehydrogenase activity
MI63_RS12535	COG0439	Biotin carboxylase
MI63_RS12540	COG0511	ligase activity, forming carbon-carbon bonds
MI63_RS12545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MI63_RS12550	COG1024	Enoyl-CoA hydratase
MI63_RS12555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MI63_RS12560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MI63_RS12570	COG1247	-acetyltransferase
MI63_RS12575	COG0572	uridine kinase
MI63_RS12585	COG2318	DinB family
MI63_RS12590	COG1686	Belongs to the peptidase S11 family
MI63_RS12615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MI63_RS12655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MI63_RS12655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MI63_RS12680	COG2814	Major facilitator Superfamily
MI63_RS12700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MI63_RS12720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS12735	COG1063	alcohol dehydrogenase
MI63_RS12750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MI63_RS12755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MI63_RS12770	COG3773	Cell wall hydrolase
MI63_RS12780	COG0745	RESPONSE REGULATOR receiver
MI63_RS12795	COG0488	(ABC) transporter
MI63_RS12810	COG1136	(ABC) transporter
MI63_RS12835	COG0460	homoserine dehydrogenase
MI63_RS12840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS12850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MI63_RS12925	COG2124	cytochrome p450
MI63_RS12965	COG0561	phosphatase activity
MI63_RS12975	COG5002	protein histidine kinase activity
MI63_RS12980	COG0768	penicillin binding
MI63_RS12985	COG1819	glycosyl
MI63_RS12990	COG1794	racemase activity, acting on amino acids and derivatives
MI63_RS13000	COG1122	ATPase activity
MI63_RS13010	COG2205	protein histidine kinase activity
MI63_RS13020	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MI63_RS13025	COG0604	alcohol dehydrogenase
MI63_RS13030	COG0768	penicillin binding
MI63_RS13040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MI63_RS13075	COG0693	protein deglycase activity
MI63_RS13105	COG2814	Major facilitator Superfamily
MI63_RS13120	COG0584	glycerophosphoryl diester phosphodiesterase
MI63_RS13140	COG0697	spore germination
MI63_RS13165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MI63_RS13175	COG2223	nitrite transmembrane transporter activity
MI63_RS13190	COG2816	NAD+ diphosphatase activity
MI63_RS13195	COG0592	DNA-directed DNA polymerase activity
MI63_RS13200	COG1051	belongs to the nudix hydrolase family
MI63_RS13235	COG3878	Protein conserved in bacteria
MI63_RS13265	COG4667	esterase of the alpha-beta hydrolase superfamily
MI63_RS13290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MI63_RS13305	COG0322	excinuclease ABC activity
MI63_RS13345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MI63_RS13370	COG1011	Hydrolase
MI63_RS13385	COG0657	acetylesterase activity
MI63_RS13390	COG0076	glutamate decarboxylase activity
MI63_RS13405	COG1523	belongs to the glycosyl hydrolase 13 family
MI63_RS13410	COG3227	Zinc metalloprotease (Elastase)
MI63_RS13430	COG0201	protein transport
MI63_RS13440	COG0697	spore germination
MI63_RS13445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS13475	COG4129	membrane
MI63_RS13480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS13495	COG2959	enzyme of heme biosynthesis
MI63_RS13515	COG3483	tryptophan 2,3-dioxygenase activity
MI63_RS13520	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MI63_RS13525	COG3844	kynureninase activity
MI63_RS13530	COG1309	transcriptional regulator
MI63_RS13560	COG3284	Transcriptional regulator
MI63_RS13580	COG1349	DNA-binding transcription factor activity
MI63_RS13600	COG1959	2 iron, 2 sulfur cluster binding
MI63_RS13615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MI63_RS13620	COG0508	dehydrogenase complex catalyzes the overall conversion of
MI63_RS13625	COG0022	dehydrogenase e1 component
MI63_RS13630	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MI63_RS13640	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS13645	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MI63_RS13645	COG0456	acetyltransferase
MI63_RS13680	COG4176	ABC-type proline glycine betaine transport system permease component
MI63_RS13685	COG0517	IMP dehydrogenase activity
MI63_RS13685	COG4175	Glycine betaine
MI63_RS13710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MI63_RS13715	COG2153	protein acetylation
MI63_RS13720	COG3397	chitin binding
MI63_RS13735	COG2205	protein histidine kinase activity
MI63_RS13765	COG2333	competence protein COMEC
MI63_RS13765	COG0658	competence protein
MI63_RS13815	COG3973	AAA domain
MI63_RS13830	COG2105	PFAM AIG2 family protein
MI63_RS13835	COG0514	ATP-dependent DNA helicase (RecQ)
MI63_RS13865	COG4637	Psort location Cytoplasmic, score
MI63_RS13890	COG3397	chitin binding
MI63_RS13900	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MI63_RS13905	COG1115	amino acid carrier protein
MI63_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS13915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MI63_RS13925	COG3938	Belongs to the proline racemase family
MI63_RS13930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MI63_RS13970	COG0586	Pfam SNARE associated Golgi protein
MI63_RS13985	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MI63_RS13990	COG0519	Catalyzes the synthesis of GMP from XMP
MI63_RS13995	COG4166	transmembrane transport
MI63_RS14005	COG4948	Mandelate Racemase Muconate Lactonizing
MI63_RS14045	COG2936	dipeptidyl-peptidase activity
MI63_RS14050	COG5002	protein histidine kinase activity
MI63_RS14055	COG0745	RESPONSE REGULATOR receiver
MI63_RS14095	COG1307	EDD domain protein, DegV family
MI63_RS14115	COG2814	Major facilitator Superfamily
MI63_RS14125	COG1664	Polymer-forming cytoskeletal
MI63_RS14130	COG0789	Transcriptional regulator
MI63_RS14135	COG4533	DNA binding
MI63_RS14140	COG2814	Major facilitator Superfamily
MI63_RS14140	COG0477	Major facilitator Superfamily
MI63_RS14160	COG2261	transglycosylase associated protein
MI63_RS14175	COG2226	methyltransferase
MI63_RS14210	COG0436	Aminotransferase
MI63_RS14215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MI63_RS14220	COG5146	pantothenate kinase activity
MI63_RS14240	COG1131	(ABC) transporter
MI63_RS14290	COG0628	permease
MI63_RS14305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MI63_RS14310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MI63_RS14315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MI63_RS14320	COG1116	anion transmembrane transporter activity
MI63_RS14340	COG2816	NAD+ diphosphatase activity
MI63_RS14360	COG2746	aminoglycoside 3-N-acetyltransferase activity
MI63_RS14385	COG0697	spore germination
MI63_RS14390	COG2318	DinB family
MI63_RS14430	COG0861	Integral membrane protein TerC family
MI63_RS14435	COG1368	sulfuric ester hydrolase activity
MI63_RS14440	COG0488	(ABC) transporter
MI63_RS14450	COG1033	growth of symbiont in host cell
MI63_RS14450	COG2409	Drug exporters of the RND superfamily
MI63_RS14455	COG1033	growth of symbiont in host cell
MI63_RS14455	COG2409	Drug exporters of the RND superfamily
MI63_RS14460	COG1309	transcriptional regulator
MI63_RS14475	COG0287	Prephenate dehydrogenase
MI63_RS14480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MI63_RS14485	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MI63_RS14490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MI63_RS14490	COG1605	Chorismate mutase
MI63_RS14525	COG1388	LysM domain
MI63_RS14525	COG3584	3D domain protein
MI63_RS14535	COG1595	DNA-templated transcription, initiation
MI63_RS14560	COG1879	ABC-type sugar transport system periplasmic component
MI63_RS14570	COG1172	Belongs to the binding-protein-dependent transport system permease family
MI63_RS14580	COG2390	Transcriptional regulator
MI63_RS14585	COG1070	Carbohydrate kinase
MI63_RS14615	COG2329	Antibiotic biosynthesis monooxygenase
MI63_RS14635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS14645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MI63_RS14650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MI63_RS14655	COG4187	Peptidase family M20/M25/M40
MI63_RS14660	COG1414	Transcriptional regulator
MI63_RS14665	COG0833	amino acid
MI63_RS14670	COG1690	Belongs to the RtcB family
MI63_RS14675	COG3239	Fatty acid desaturase
MI63_RS14680	COG1785	Belongs to the alkaline phosphatase family
MI63_RS14690	COG3655	Transcriptional regulator
MI63_RS14705	COG4377	Putative membrane peptidase family (DUF2324)
MI63_RS14715	COG3279	Response regulator of the LytR AlgR family
MI63_RS14725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS14730	COG0346	lactoylglutathione lyase activity
MI63_RS14750	COG0714	Associated with various cellular activities
MI63_RS14800	COG0463	Glycosyl transferase, family 2
MI63_RS14810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MI63_RS14815	COG0753	catalase activity
MI63_RS14825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MI63_RS14850	COG0714	Associated with various cellular activities
MI63_RS14860	COG0778	Nitroreductase
MI63_RS14865	COG1846	Transcriptional regulator
MI63_RS14900	COG1725	Transcriptional regulator
MI63_RS14910	COG1136	(ABC) transporter
MI63_RS14910	COG0577	efflux transmembrane transporter activity
MI63_RS14935	COG2207	Transcriptional regulator
MI63_RS14940	COG0456	acetyltransferase
MI63_RS14960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS14980	COG0642	Histidine kinase
MI63_RS14985	COG0745	RESPONSE REGULATOR receiver
MI63_RS14990	COG0596	Alpha beta hydrolase
MI63_RS15020	COG0730	response to heat
MI63_RS15030	COG0833	amino acid
MI63_RS15040	COG4335	DNA alkylation repair
MI63_RS15080	COG0768	penicillin binding
MI63_RS15090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MI63_RS15125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MI63_RS15130	COG1414	Transcriptional regulator
MI63_RS15145	COG0860	N-Acetylmuramoyl-L-alanine amidase
MI63_RS15150	COG0640	Transcriptional regulator
MI63_RS15160	COG1960	acyl-CoA dehydrogenase activity
MI63_RS15180	COG3314	Sporulation integral membrane protein YlbJ
MI63_RS15195	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MI63_RS15210	COG0574	Belongs to the PEP-utilizing enzyme family
MI63_RS15210	COG3848	Pyruvate phosphate dikinase
MI63_RS15215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS15230	COG5577	PFAM Coat F domain
MI63_RS15235	COG3403	YqcI/YcgG family
MI63_RS15240	COG1280	lysine exporter protein (LysE YggA)
MI63_RS15275	COG1063	alcohol dehydrogenase
MI63_RS15295	COG0252	asparaginase activity
MI63_RS15300	COG1396	sequence-specific DNA binding
MI63_RS15310	COG0322	excinuclease ABC activity
MI63_RS15320	COG1114	Component of the transport system for branched-chain amino acids
MI63_RS15325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MI63_RS15335	COG0281	malic enzyme
MI63_RS15350	COG0531	amino acid
MI63_RS15355	COG0697	spore germination
MI63_RS15360	COG0784	Response regulator, receiver
MI63_RS15370	COG2066	Belongs to the glutaminase family
MI63_RS15375	COG1115	amino acid carrier protein
MI63_RS15400	COG0737	Belongs to the 5'-nucleotidase family
MI63_RS15405	COG0753	catalase activity
MI63_RS15410	COG2267	carboxylic ester hydrolase activity
MI63_RS15415	COG1335	isochorismatase
MI63_RS15435	COG0583	DNA-binding transcription factor activity
MI63_RS15445	COG0598	Magnesium transport protein CorA
MI63_RS15480	COG0415	Belongs to the DNA photolyase family
MI63_RS15485	COG0288	reversible hydration of carbon dioxide
MI63_RS15495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MI63_RS15500	COG5609	conserved protein (DUF2294)
MI63_RS15510	COG1575	Belongs to the MenA family. Type 1 subfamily
MI63_RS15515	COG2267	carboxylic ester hydrolase activity
MI63_RS15520	COG0803	Belongs to the bacterial solute-binding protein 9 family
MI63_RS15525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MI63_RS15530	COG1121	(ABC) transporter
MI63_RS15560	COG0798	PFAM Bile acid sodium symporter
MI63_RS15565	COG0346	lactoylglutathione lyase activity
MI63_RS15570	COG0640	Transcriptional regulator
MI63_RS15585	COG0443	Heat shock 70 kDa protein
MI63_RS15600	COG1522	sequence-specific DNA binding
MI63_RS15615	COG0346	lactoylglutathione lyase activity
MI63_RS15635	COG2169	Transcriptional regulator
MI63_RS15680	COG2814	Major facilitator Superfamily
MI63_RS15705	COG0745	RESPONSE REGULATOR receiver
MI63_RS15710	COG3850	Histidine kinase
MI63_RS15710	COG5002	protein histidine kinase activity
MI63_RS15740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MI63_RS15765	COG1476	TRANSCRIPTIONal
MI63_RS15780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS15785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MI63_RS15795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MI63_RS15800	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MI63_RS15815	COG1136	(ABC) transporter
MI63_RS15820	COG0577	efflux transmembrane transporter activity
MI63_RS15840	COG3850	Histidine kinase
MI63_RS15840	COG5002	protein histidine kinase activity
MI63_RS15850	COG2364	Membrane
MI63_RS15855	COG1846	Transcriptional regulator
MI63_RS15865	COG2808	Putative FMN-binding domain
MI63_RS15870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS15875	COG2271	Major facilitator Superfamily
MI63_RS15880	COG1556	Lactate utilization protein
MI63_RS15885	COG1139	Iron-sulfur cluster binding protein
MI63_RS15895	COG0583	DNA-binding transcription factor activity
MI63_RS15905	COG1619	proteins homologs of microcin C7 resistance protein MccF
MI63_RS15935	COG0673	inositol 2-dehydrogenase activity
MI63_RS15940	COG0561	phosphatase activity
MI63_RS15950	COG1609	Transcriptional regulator
MI63_RS15955	COG0457	Tetratricopeptide repeat
MI63_RS15975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MI63_RS16005	COG0534	Mate efflux family protein
MI63_RS16020	COG2814	Major facilitator Superfamily
MI63_RS16025	COG1309	transcriptional regulator
MI63_RS16040	COG0814	amino acid
MI63_RS16045	COG1760	l-serine dehydratase
MI63_RS16050	COG1760	l-serine dehydratase
MI63_RS16060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MI63_RS16065	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
MI63_RS16080	COG1522	sequence-specific DNA binding
MI63_RS16085	COG0531	amino acid
MI63_RS16100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MI63_RS16120	COG1595	DNA-templated transcription, initiation
MI63_RS16135	COG0662	Cupin 2, conserved barrel domain protein
MI63_RS16145	COG2207	Transcriptional regulator
MI63_RS16145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS16200	COG0477	Major facilitator Superfamily
MI63_RS16210	COG1846	Transcriptional regulator
MI63_RS16215	COG2814	Major facilitator Superfamily
MI63_RS16230	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MI63_RS16235	COG1131	(ABC) transporter
MI63_RS16255	COG2076	Multidrug Resistance protein
MI63_RS16260	COG1309	transcriptional regulator
MI63_RS16275	COG2031	fatty acid transporter
MI63_RS16285	COG2249	NAD(P)H dehydrogenase (quinone) activity
MI63_RS16315	COG1122	ATPase activity
MI63_RS16320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MI63_RS16335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MI63_RS16340	COG1288	antiporter activity
MI63_RS16345	COG2356	endonuclease I
MI63_RS16360	COG3620	sequence-specific DNA binding
MI63_RS16365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MI63_RS16370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MI63_RS16375	COG0124	histidyl-tRNA synthetase
MI63_RS16390	COG1733	regulation of RNA biosynthetic process
MI63_RS16395	COG0778	Nitroreductase
MI63_RS16415	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS16425	COG1131	(ABC) transporter
MI63_RS16450	COG1011	Hydrolase
MI63_RS16460	COG2365	Tyrosine phosphatase family
MI63_RS16485	COG0346	lactoylglutathione lyase activity
MI63_RS16490	COG1940	carbohydrate kinase activity
MI63_RS16495	COG0738	Major facilitator superfamily
MI63_RS16500	COG0110	maltose O-acetyltransferase activity
MI63_RS16510	COG0577	efflux transmembrane transporter activity
MI63_RS16510	COG1136	(ABC) transporter
MI63_RS16520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MI63_RS16525	COG0628	permease
MI63_RS16545	COG2226	methyltransferase
MI63_RS16555	COG0477	Major facilitator Superfamily
MI63_RS16585	COG1253	flavin adenine dinucleotide binding
MI63_RS16590	COG0789	Transcriptional regulator
MI63_RS16595	COG0697	spore germination
MI63_RS16600	COG1357	PFAM Pentapeptide repeats (8 copies)
MI63_RS16605	COG3813	Protein conserved in bacteria
MI63_RS16610	COG2706	6-phosphogluconolactonase activity
MI63_RS16615	COG1070	Carbohydrate kinase
MI63_RS16625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MI63_RS16630	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MI63_RS16645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MI63_RS16650	COG0604	alcohol dehydrogenase
MI63_RS16655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MI63_RS16665	COG3321	synthase
MI63_RS16665	COG0604	alcohol dehydrogenase
MI63_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS16700	COG0656	L-ascorbic acid biosynthetic process
MI63_RS16705	COG2814	Major facilitator Superfamily
MI63_RS16720	COG0346	lactoylglutathione lyase activity
MI63_RS16725	COG0814	amino acid
MI63_RS16750	COG1393	Belongs to the ArsC family
MI63_RS16760	COG1733	regulation of RNA biosynthetic process
MI63_RS16765	COG2188	Transcriptional regulator
MI63_RS16770	COG0673	inositol 2-dehydrogenase activity
MI63_RS16775	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MI63_RS16780	COG1733	regulation of RNA biosynthetic process
MI63_RS16785	COG1733	regulation of RNA biosynthetic process
MI63_RS16800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS16820	COG0384	phenazine biosynthesis protein PhzF
MI63_RS16830	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS16840	COG0318	PFAM AMP-dependent synthetase and ligase
MI63_RS16850	COG1733	regulation of RNA biosynthetic process
MI63_RS16880	COG1191	sigma factor activity
MI63_RS16895	COG1309	transcriptional regulator
MI63_RS16915	COG3152	Membrane
MI63_RS16940	COG1151	hydroxylamine reductase activity
MI63_RS16950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS16955	COG3757	hydrolase, family 25
MI63_RS16955	COG3409	Peptidoglycan-binding domain 1 protein
MI63_RS16990	COG2072	flavoprotein involved in K transport
MI63_RS17025	COG0604	alcohol dehydrogenase
MI63_RS17030	COG1113	amino acid transport
MI63_RS17035	COG2814	Major facilitator Superfamily
MI63_RS17070	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MI63_RS17075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MI63_RS17095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS17105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS17110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS17115	COG3739	integral membrane protein
MI63_RS17120	COG0384	phenazine biosynthesis protein PhzF
MI63_RS17150	COG0583	DNA-binding transcription factor activity
MI63_RS17170	COG1193	negative regulation of DNA recombination
MI63_RS17185	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MI63_RS17190	COG1164	Oligoendopeptidase f
MI63_RS17195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MI63_RS17225	COG0584	glycerophosphoryl diester phosphodiesterase
MI63_RS17250	COG0640	Transcriptional regulator
MI63_RS17255	COG0604	alcohol dehydrogenase
MI63_RS17275	COG2808	Putative FMN-binding domain
MI63_RS17290	COG0385	Bile acid
MI63_RS17295	COG0277	FAD linked oxidase domain protein
MI63_RS17330	COG1216	Glycosyl transferase, family 2
MI63_RS17335	COG1024	Enoyl-CoA hydratase
MI63_RS17345	COG1285	pathogenesis
MI63_RS17355	COG2514	catechol 2,3-dioxygenase activity
MI63_RS17360	COG2720	vancomycin resistance protein
MI63_RS17400	COG0716	FMN binding
MI63_RS17430	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS17455	COG4145	pantothenate transmembrane transporter activity
MI63_RS17465	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS17480	COG1657	PFAM Prenyltransferase squalene oxidase
MI63_RS17485	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MI63_RS17490	COG2962	Rard protein
MI63_RS17495	COG3326	Membrane
MI63_RS17510	COG0489	protein tyrosine kinase activity
MI63_RS17520	COG0314	molybdopterin synthase activity
MI63_RS17525	COG0303	'Molybdopterin
MI63_RS17530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MI63_RS17535	COG2116	formate transmembrane transporter activity
MI63_RS17545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MI63_RS17550	COG5609	conserved protein (DUF2294)
MI63_RS17555	COG2427	Protein of unknown function (DUF1641)
MI63_RS17570	COG0697	spore germination
MI63_RS17610	COG2226	methyltransferase
MI63_RS17615	COG4166	transmembrane transport
MI63_RS17620	COG4166	transmembrane transport
MI63_RS17625	COG1301	dicarboxylic acid transport
MI63_RS17630	COG1316	TRANSCRIPTIONal
MI63_RS17640	COG1595	DNA-templated transcription, initiation
MI63_RS17665	COG1131	(ABC) transporter
MI63_RS17675	COG0673	inositol 2-dehydrogenase activity
MI63_RS17680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MI63_RS17685	COG0187	DNA topoisomerase II activity
MI63_RS17695	COG1832	CoA-binding protein
MI63_RS17700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MI63_RS17705	COG0745	RESPONSE REGULATOR receiver
MI63_RS17720	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MI63_RS17725	COG4841	protein insertion into membrane
MI63_RS17730	COG0824	Thioesterase
MI63_RS17760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MI63_RS17770	COG2274	protein secretion by the type I secretion system
MI63_RS17775	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MI63_RS17805	COG2211	Major facilitator Superfamily
MI63_RS17815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MI63_RS17830	COG0183	Belongs to the thiolase family
MI63_RS17835	COG0318	PFAM AMP-dependent synthetase and ligase
MI63_RS17840	COG1268	BioY protein
MI63_RS17845	COG0318	PFAM AMP-dependent synthetase and ligase
MI63_RS17890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS17900	COG5002	protein histidine kinase activity
MI63_RS17905	COG0400	carboxylic ester hydrolase activity
MI63_RS17910	COG0346	lactoylglutathione lyase activity
MI63_RS17915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MI63_RS17920	COG0069	glutamate synthase activity
MI63_RS17925	COG1902	pentaerythritol trinitrate reductase activity
MI63_RS17930	COG1329	Transcriptional regulator
MI63_RS17935	COG0010	Belongs to the arginase family
MI63_RS17960	COG2226	methyltransferase
MI63_RS18015	COG4846	Membrane protein involved in cytochrome C biogenesis
MI63_RS18020	COG0785	Cytochrome C biogenesis protein
MI63_RS18030	COG0583	DNA-binding transcription factor activity
MI63_RS18035	COG1380	Effector of murein hydrolase LrgA
MI63_RS18040	COG1346	cytolysis
MI63_RS18055	COG0730	response to heat
MI63_RS18065	COG5632	N-Acetylmuramoyl-L-alanine amidase
MI63_RS18065	COG3409	Peptidoglycan-binding domain 1 protein
MI63_RS18080	COG1132	(ABC) transporter
MI63_RS18085	COG1132	(ABC) transporter
MI63_RS18120	COG3639	organic phosphonate transmembrane transporter activity
MI63_RS18125	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MI63_RS18140	COG0737	Belongs to the 5'-nucleotidase family
MI63_RS18150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MI63_RS18170	COG1695	Transcriptional regulator
MI63_RS18205	COG1388	LysM domain
MI63_RS18205	COG3409	Peptidoglycan-binding domain 1 protein
MI63_RS18205	COG5632	N-Acetylmuramoyl-L-alanine amidase
MI63_RS18210	COG4824	toxin secretion phage lysis holin
MI63_RS18370	COG1595	DNA-templated transcription, initiation
MI63_RS18415	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
MI63_RS18495	COG1396	sequence-specific DNA binding
MI63_RS18520	COG0174	glutamine synthetase
MI63_RS18525	COG0789	Transcriptional regulator
MI63_RS18530	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MI63_RS18535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MI63_RS18540	COG2860	membrane
MI63_RS18545	COG0464	growth
MI63_RS18575	COG3584	3D domain protein
MI63_RS18575	COG1388	LysM domain
MI63_RS18580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MI63_RS18580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MI63_RS18580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MI63_RS18585	COG1105	Belongs to the carbohydrate kinase PfkB family
MI63_RS18590	COG1349	DNA-binding transcription factor activity
MI63_RS18600	COG2322	membrane
MI63_RS18615	COG1113	amino acid transport
MI63_RS18625	COG1408	metallophosphoesterase
MI63_RS18630	COG2116	formate transmembrane transporter activity
MI63_RS18640	COG2217	Heavy metal translocating P-type atpase
MI63_RS18645	COG2608	mercury ion transmembrane transporter activity
MI63_RS18650	COG1937	Protein conserved in bacteria
MI63_RS18660	COG2819	hydrolase of the alpha beta superfamily
MI63_RS18665	COG1120	ATPase activity
MI63_RS18670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS18675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS18680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS18695	COG2169	Transcriptional regulator
MI63_RS18700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MI63_RS18705	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MI63_RS18715	COG2364	Membrane
MI63_RS18730	COG2267	carboxylic ester hydrolase activity
MI63_RS18735	COG0346	lactoylglutathione lyase activity
MI63_RS18760	COG1346	cytolysis
MI63_RS18765	COG1380	Effector of murein hydrolase LrgA
MI63_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MI63_RS18775	COG0596	Alpha beta hydrolase
MI63_RS18775	COG0508	dehydrogenase complex catalyzes the overall conversion of
MI63_RS18780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MI63_RS18795	COG1404	Belongs to the peptidase S8 family
MI63_RS18800	COG3773	Cell wall hydrolase
MI63_RS18805	COG0562	UDP-galactopyranose mutase
MI63_RS18810	COG1368	sulfuric ester hydrolase activity
MI63_RS18815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MI63_RS18825	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
MI63_RS18850	COG1131	(ABC) transporter
MI63_RS18870	COG4550	Control of competence regulator ComK, YlbF/YmcA
MI63_RS18875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MI63_RS18880	COG1013	pyruvate-flavodoxin oxidoreductase activity
MI63_RS18885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MI63_RS18885	COG0674	pyruvate-flavodoxin oxidoreductase activity
MI63_RS18895	COG2359	stage V sporulation protein S
MI63_RS18900	COG1692	metallophosphoesterase
MI63_RS18925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MI63_RS18930	COG1426	Protein conserved in bacteria
MI63_RS18945	COG0300	oxidoreductase activity
MI63_RS18950	COG0612	Peptidase, M16
MI63_RS18955	COG0612	Peptidase, M16
MI63_RS18960	COG1079	Belongs to the binding-protein-dependent transport system permease family
MI63_RS18965	COG4603	Belongs to the binding-protein-dependent transport system permease family
MI63_RS18970	COG4603	Belongs to the binding-protein-dependent transport system permease family
MI63_RS18975	COG3845	ABC transporter
MI63_RS18980	COG1744	ABC transporter substrate-binding protein PnrA-like
MI63_RS18985	COG2188	Transcriptional regulator
MI63_RS18990	COG1674	ftsk spoiiie
MI63_RS19000	COG0740	serine-type endopeptidase activity
MI63_RS19005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MI63_RS19020	COG0527	aspartate kinase activity
MI63_RS19025	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MI63_RS19030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MI63_RS19035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MI63_RS19040	COG1873	PFAM PRC-barrel domain
MI63_RS19045	COG0612	Peptidase, M16
MI63_RS19050	COG0726	polysaccharide deacetylase
MI63_RS19065	COG0196	riboflavin kinase activity
MI63_RS19070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MI63_RS19080	COG1550	Protein conserved in bacteria
MI63_RS19090	COG1358	cellular component organization or biogenesis
MI63_RS19095	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MI63_RS19100	COG0195	Participates in both transcription termination and antitermination
MI63_RS19120	COG0750	zinc metalloprotease
MI63_RS19130	COG4589	Belongs to the CDS family
MI63_RS19145	COG0528	UMP kinase activity
MI63_RS19175	COG4974	Belongs to the 'phage' integrase family
MI63_RS19185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MI63_RS19195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MI63_RS19235	COG1837	Belongs to the UPF0109 family
MI63_RS19245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MI63_RS19255	COG0552	protein localization to endoplasmic reticulum
MI63_RS19260	COG1196	nuclear chromosome segregation
MI63_RS19270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MI63_RS19275	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS19280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MI63_RS19295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MI63_RS19300	COG1461	Dihydroxyacetone kinase
MI63_RS19305	COG1302	Protein conserved in bacteria
MI63_RS19320	COG1564	THIamine pyrophosphokinase
MI63_RS19325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MI63_RS19330	COG1162	GTPase activity
MI63_RS19335	COG2815	serine threonine protein kinase
MI63_RS19335	COG0515	serine threonine protein kinase
MI63_RS19340	COG0631	protein serine/threonine phosphatase activity
MI63_RS19350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MI63_RS19350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MI63_RS19360	COG0242	peptide deformylase activity
MI63_RS19365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MI63_RS19370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MI63_RS19390	COG1561	YicC-like family, N-terminal region
MI63_RS19395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MI63_RS19405	COG0006	proline dipeptidase activity
MI63_RS19420	COG3069	C4-dicarboxylate transmembrane transporter activity
MI63_RS19485	COG0564	pseudouridine synthase activity
MI63_RS19505	COG3599	regulation of cell shape
MI63_RS19510	COG2302	S4 RNA-binding domain
MI63_RS19515	COG0762	integral membrane protein
MI63_RS19525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MI63_RS19530	COG1496	oxidoreductase activity
MI63_RS19535	COG1873	PFAM PRC-barrel domain
MI63_RS19540	COG1191	sigma factor activity
MI63_RS19545	COG1191	sigma factor activity
MI63_RS19555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MI63_RS19560	COG0849	cell division
MI63_RS19565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MI63_RS19570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MI63_RS19580	COG0772	Belongs to the SEDS family
MI63_RS19595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MI63_RS19600	COG0768	penicillin binding
MI63_RS19605	COG0768	penicillin binding
MI63_RS19610	COG4839	cell division protein FtsL
MI63_RS19625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MI63_RS19640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MI63_RS19645	COG1399	metal-binding, possibly nucleic acid-binding protein
MI63_RS19695	COG4824	toxin secretion phage lysis holin
MI63_RS19790	COG1802	Transcriptional regulator
MI63_RS19790	COG4626	Terminase
MI63_RS19815	COG0582	viral genome integration into host DNA
MI63_RS19885	COG0756	dUTP diphosphatase activity
MI63_RS19920	COG1484	DNA-dependent DNA replication
MI63_RS19950	COG1396	sequence-specific DNA binding
MI63_RS19960	COG1396	sequence-specific DNA binding
MI63_RS19975	COG0582	viral genome integration into host DNA
MI63_RS19985	COG3480	Lon protease (S16) C-terminal proteolytic domain
MI63_RS19990	COG1752	Esterase of the alpha-beta hydrolase superfamily
MI63_RS19995	COG3314	Sporulation integral membrane protein YlbJ
MI63_RS20005	COG0742	ribosomal rna small subunit methyltransferase
MI63_RS20020	COG3679	Belongs to the UPF0342 family
MI63_RS20025	COG0406	alpha-ribazole phosphatase activity
MI63_RS20040	COG2340	Cysteine-rich secretory protein family
MI63_RS20055	COG3336	cytochrome c oxidase
MI63_RS20090	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MI63_RS20095	COG0772	Belongs to the SEDS family
MI63_RS20105	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MI63_RS20110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MI63_RS20120	COG4896	Protein conserved in bacteria
MI63_RS20135	COG1217	gtp-binding protein TYPA
MI63_RS20145	COG0483	inositol monophosphate 1-phosphatase activity
MI63_RS20165	COG1982	Orn Lys Arg decarboxylase major
MI63_RS20215	COG0022	dehydrogenase e1 component
MI63_RS20220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MI63_RS20230	COG0242	peptide deformylase activity
MI63_RS20235	COG0561	phosphatase activity
MI63_RS20245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MI63_RS20250	COG0569	domain protein
MI63_RS20270	COG0583	DNA-binding transcription factor activity
MI63_RS20275	COG0517	IMP dehydrogenase activity
MI63_RS20285	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MI63_RS20295	COG4703	Protein of unknown function (DUF1797)
MI63_RS20310	COG2200	EAL domain
MI63_RS20315	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS20320	COG1408	metallophosphoesterase
MI63_RS20370	COG2814	Major facilitator Superfamily
MI63_RS20395	COG3209	COG3209 Rhs family protein
MI63_RS20405	COG2205	protein histidine kinase activity
MI63_RS20415	COG0436	Aminotransferase
MI63_RS20420	COG1609	Transcriptional regulator
MI63_RS20425	COG3833	ABC-type maltose transport systems, permease component
MI63_RS20430	COG1175	transmembrane transport
MI63_RS20435	COG2182	Extracellular solute-binding protein
MI63_RS20445	COG0366	Alpha amylase catalytic
MI63_RS20450	COG3842	ATPase activity
MI63_RS20490	COG0183	Belongs to the thiolase family
MI63_RS20530	COG1695	Transcriptional regulator
MI63_RS20535	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS20545	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MI63_RS20555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MI63_RS20560	COG0436	Aminotransferase
MI63_RS20580	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MI63_RS20600	COG2199	diguanylate cyclase activity
MI63_RS20605	COG0778	Nitroreductase
MI63_RS20630	COG1263	PTS System
MI63_RS20630	COG2190	(PTS) system
MI63_RS20630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MI63_RS20635	COG3711	transcriptional antiterminator
MI63_RS20645	COG2188	Transcriptional regulator
MI63_RS20655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MI63_RS20685	COG1547	Domain of unknown function (DUF309)
MI63_RS20690	COG0456	acetyltransferase
MI63_RS20700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MI63_RS20705	COG4086	secreted protein
MI63_RS20710	COG0561	phosphatase activity
MI63_RS20715	COG0697	spore germination
MI63_RS20730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MI63_RS20755	COG0733	neurotransmitter:sodium symporter activity
MI63_RS20775	COG1686	Belongs to the peptidase S11 family
MI63_RS20780	COG1725	Transcriptional regulator
MI63_RS20785	COG1131	(ABC) transporter
MI63_RS20805	COG1846	Transcriptional regulator
MI63_RS20820	COG0598	Magnesium transport protein CorA
MI63_RS20845	COG4974	Belongs to the 'phage' integrase family
MI63_RS20855	COG0735	belongs to the Fur family
MI63_RS20860	COG1300	Membrane
MI63_RS20880	COG0667	Aldo Keto reductase
MI63_RS20885	COG0656	L-ascorbic acid biosynthetic process
MI63_RS20890	COG0456	acetyltransferase
MI63_RS20890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MI63_RS20900	COG4085	toxin activity
MI63_RS20900	COG0737	Belongs to the 5'-nucleotidase family
MI63_RS20900	COG1525	nuclease
MI63_RS20910	COG0596	Alpha beta hydrolase
MI63_RS20915	COG2056	Na+-H+ antiporter family
MI63_RS20920	COG1609	Transcriptional regulator
MI63_RS20925	COG0456	acetyltransferase
MI63_RS20930	COG1073	alpha beta
MI63_RS20945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MI63_RS20945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MI63_RS20950	COG0307	riboflavin synthase, alpha
MI63_RS20975	COG4106	trans-aconitate 2-methyltransferase activity
MI63_RS20980	COG2226	methyltransferase
MI63_RS20980	COG1073	alpha beta
MI63_RS20995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MI63_RS21005	COG1757	Na H antiporter
MI63_RS21010	COG0737	Belongs to the 5'-nucleotidase family
MI63_RS21020	COG1522	sequence-specific DNA binding
MI63_RS21040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MI63_RS21050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MI63_RS21065	COG0300	oxidoreductase activity
MI63_RS21070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS21075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MI63_RS21080	COG1760	l-serine dehydratase
MI63_RS21085	COG1760	l-serine dehydratase
MI63_RS21105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MI63_RS21115	COG2195	Cleaves the N-terminal amino acid of tripeptides
MI63_RS21120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS21135	COG1376	ErfK ybiS ycfS ynhG family protein
MI63_RS21140	COG4129	membrane
MI63_RS21145	COG1126	abc transporter atp-binding protein
MI63_RS21150	COG0765	amino acid transport
MI63_RS21155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MI63_RS21175	COG2816	NAD+ diphosphatase activity
MI63_RS21180	COG0772	Belongs to the SEDS family
MI63_RS21190	COG0508	dehydrogenase complex catalyzes the overall conversion of
MI63_RS21195	COG0022	dehydrogenase e1 component
MI63_RS21200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MI63_RS21205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MI63_RS21220	COG0280	phosphate acetyltransferase
MI63_RS21230	COG3829	transcription factor binding
MI63_RS21230	COG3290	protein histidine kinase activity
MI63_RS21240	COG0584	glycerophosphoryl diester phosphodiesterase
MI63_RS21245	COG3093	addiction module antidote protein HigA
MI63_RS21255	COG0745	RESPONSE REGULATOR receiver
MI63_RS21260	COG0750	zinc metalloprotease
MI63_RS21265	COG0497	DNA recombination
MI63_RS21275	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MI63_RS21285	COG0142	geranyltranstransferase activity
MI63_RS21310	COG1302	Protein conserved in bacteria
MI63_RS21315	COG0439	Biotin carboxylase
MI63_RS21320	COG0511	ligase activity, forming carbon-carbon bonds
MI63_RS21365	COG3854	ATPases associated with a variety of cellular activities
MI63_RS21390	COG0006	proline dipeptidase activity
MI63_RS21405	COG3872	metal-dependent enzyme
MI63_RS21415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MI63_RS21435	COG0095	Lipoate-protein ligase
MI63_RS21440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MI63_RS21445	COG1609	Transcriptional regulator
MI63_RS21455	COG2076	Multidrug Resistance protein
MI63_RS21460	COG2076	Multidrug Resistance protein
MI63_RS21500	COG1131	(ABC) transporter
MI63_RS21505	COG1725	Transcriptional regulator
MI63_RS21535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MI63_RS21590	COG4970	Tfp pilus assembly protein FimT
MI63_RS21595	COG4537	Required for transformation and DNA binding
MI63_RS21600	COG1459	type II secretion system
MI63_RS21605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MI63_RS21655	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MI63_RS21665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MI63_RS21665	COG0646	methionine synthase
MI63_RS21675	COG0626	cystathionine gamma-synthase activity
MI63_RS21680	COG0626	cystathionine gamma-synthase activity
MI63_RS21705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS21715	COG1940	carbohydrate kinase activity
MI63_RS21720	COG4483	Protein conserved in bacteria
MI63_RS21725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MI63_RS21730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MI63_RS21735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MI63_RS21740	COG0704	Plays a role in the regulation of phosphate uptake
MI63_RS21750	COG0581	inorganic phosphate transmembrane transporter activity
MI63_RS21755	COG0573	inorganic phosphate transmembrane transporter activity
MI63_RS21760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MI63_RS21765	COG0768	penicillin binding
MI63_RS21770	COG0477	Major facilitator Superfamily
MI63_RS21775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MI63_RS21800	COG0735	belongs to the Fur family
MI63_RS21805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MI63_RS21810	COG1121	(ABC) transporter
MI63_RS21815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS21845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MI63_RS21850	COG2384	SAM-dependent methyltransferase
MI63_RS21855	COG2010	Cytochrome c
MI63_RS21860	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MI63_RS21865	COG0358	DNA primase activity
MI63_RS21885	COG0517	IMP dehydrogenase activity
MI63_RS21900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MI63_RS21905	COG0295	cytidine deaminase activity
MI63_RS21910	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MI63_RS21920	COG1480	7TM receptor with intracellular HD hydrolase
MI63_RS21925	COG1702	phosphate starvation-inducible protein PhoH
MI63_RS21945	COG1610	YqeY-like protein
MI63_RS21950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MI63_RS21955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MI63_RS21960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MI63_RS21990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MI63_RS21995	COG1733	regulation of RNA biosynthetic process
MI63_RS22020	COG1466	dna polymerase III delta subunit
MI63_RS22035	COG2131	deaminase
MI63_RS22040	COG1596	polysaccharide export
MI63_RS22040	COG1555	photosystem II stabilization
MI63_RS22045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MI63_RS22050	COG2226	methyltransferase
MI63_RS22055	COG0799	negative regulation of ribosome biogenesis
MI63_RS22060	COG1713	HD superfamily hydrolase involved in NAD metabolism
MI63_RS22070	COG1534	Rna-binding protein
MI63_RS22080	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MI63_RS22085	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MI63_RS22110	COG1595	DNA-templated transcription, initiation
MI63_RS22120	COG0778	Nitroreductase
MI63_RS22125	COG2357	RelA SpoT domain protein
MI63_RS22135	COG1785	Belongs to the alkaline phosphatase family
MI63_RS22145	COG2267	carboxylic ester hydrolase activity
MI63_RS22180	COG1404	Belongs to the peptidase S8 family
MI63_RS22185	COG3186	Phenylalanine-4-hydroxylase
MI63_RS22195	COG2514	catechol 2,3-dioxygenase activity
MI63_RS22200	COG2259	Doxx family
MI63_RS22240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS22250	COG1454	alcohol dehydrogenase
MI63_RS22250	COG1012	belongs to the aldehyde dehydrogenase family
MI63_RS22255	COG0626	cystathionine gamma-synthase activity
MI63_RS22260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MI63_RS22285	COG0768	penicillin binding
MI63_RS22300	COG0826	peptidase U32
MI63_RS22305	COG0826	peptidase U32
MI63_RS22310	COG4122	O-methyltransferase activity
MI63_RS22315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MI63_RS22335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MI63_RS22345	COG0628	permease
MI63_RS22365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MI63_RS22375	COG0482	sulfurtransferase activity
MI63_RS22380	COG1104	cysteine desulfurase activity
MI63_RS22385	COG1959	2 iron, 2 sulfur cluster binding
MI63_RS22390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MI63_RS22400	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MI63_RS22425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MI63_RS22435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MI63_RS22435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MI63_RS22440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MI63_RS22445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MI63_RS22445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MI63_RS22455	COG2244	polysaccharide biosynthetic process
MI63_RS22460	COG2323	membrane
MI63_RS22470	COG1862	Preprotein translocase
MI63_RS22500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MI63_RS22510	COG0697	spore germination
MI63_RS22515	COG0697	spore germination
MI63_RS22520	COG0640	Transcriptional regulator
MI63_RS22545	COG0157	Belongs to the NadC ModD family
MI63_RS22550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MI63_RS22555	COG1104	cysteine desulfurase activity
MI63_RS22560	COG1827	regulation of RNA biosynthetic process
MI63_RS22565	COG2258	MOSC domain
MI63_RS22570	COG0077	Prephenate dehydratase
MI63_RS22575	COG0577	efflux transmembrane transporter activity
MI63_RS22580	COG0577	efflux transmembrane transporter activity
MI63_RS22585	COG1136	(ABC) transporter
MI63_RS22590	COG5002	protein histidine kinase activity
MI63_RS22600	COG0745	RESPONSE REGULATOR receiver
MI63_RS22605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MI63_RS22610	COG3290	protein histidine kinase activity
MI63_RS22620	COG2868	ribosomal protein
MI63_RS22630	COG1530	ribonuclease E activity
MI63_RS22635	COG1994	Peptidase M50
MI63_RS22640	COG0739	heme binding
MI63_RS22645	COG2894	cell division
MI63_RS22665	COG1077	Cell shape determining protein MreB Mrl
MI63_RS22685	COG0285	dihydrofolate synthase activity
MI63_RS22690	COG0525	valine-tRNA ligase activity
MI63_RS22700	COG1388	LysM domain
MI63_RS22710	COG0113	porphobilinogen synthase activity
MI63_RS22715	COG1587	Uroporphyrinogen-III synthase
MI63_RS22725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MI63_RS22735	COG1846	Transcriptional regulator
MI63_RS22740	COG1764	response to oxidative stress
MI63_RS22755	COG1067	ATP-dependent peptidase activity
MI63_RS22755	COG0470	DNA polymerase III
MI63_RS22805	COG0622	Phosphoesterase
MI63_RS22820	COG5401	PFAM Sporulation and spore germination
MI63_RS22840	COG1309	transcriptional regulator
MI63_RS22855	COG2197	response regulator
MI63_RS22860	COG2233	PERMEase
MI63_RS22870	COG0402	S-adenosylhomocysteine deaminase activity
MI63_RS22875	COG0402	S-adenosylhomocysteine deaminase activity
MI63_RS22885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MI63_RS22895	COG0444	Belongs to the ABC transporter superfamily
MI63_RS22900	COG4608	Belongs to the ABC transporter superfamily
MI63_RS22905	COG3275	phosphorelay sensor kinase activity
MI63_RS22910	COG3279	Response regulator of the LytR AlgR family
MI63_RS22925	COG1983	PspC domain protein
MI63_RS22930	COG1396	sequence-specific DNA binding
MI63_RS22935	COG0697	spore germination
MI63_RS22945	COG1959	2 iron, 2 sulfur cluster binding
MI63_RS22950	COG1668	transmembrane transport
MI63_RS22960	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MI63_RS22970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MI63_RS22975	COG1876	peptidase activity
MI63_RS22980	COG0824	Thioesterase
MI63_RS22985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MI63_RS22990	COG1053	succinate dehydrogenase
MI63_RS22995	COG2009	succinate dehydrogenase
MI63_RS23000	COG1719	4-vinyl reductase, 4VR
MI63_RS23010	COG3118	belongs to the thioredoxin family
MI63_RS23015	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MI63_RS23020	COG2086	electron transfer activity
MI63_RS23025	COG1024	Enoyl-CoA hydratase
MI63_RS23030	COG1309	transcriptional regulator
MI63_RS23035	COG0318	PFAM AMP-dependent synthetase and ligase
MI63_RS23055	COG2318	DinB family
MI63_RS23085	COG1131	(ABC) transporter
MI63_RS23090	COG2205	protein histidine kinase activity
MI63_RS23095	COG0745	RESPONSE REGULATOR receiver
MI63_RS23105	COG4895	conserved protein (DUF2196)
MI63_RS23110	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MI63_RS23125	COG4509	Sortase family
MI63_RS23130	COG1120	ATPase activity
MI63_RS23145	COG5386	Cell surface protein
MI63_RS23155	COG5386	Cell surface protein
MI63_RS23160	COG1114	Component of the transport system for branched-chain amino acids
MI63_RS23165	COG1187	pseudouridine synthase activity
MI63_RS23180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MI63_RS23180	COG1796	DNA polymerase
MI63_RS23185	COG1286	toxin biosynthetic process
MI63_RS23230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MI63_RS23240	COG1418	mRNA catabolic process
MI63_RS23265	COG2814	Major facilitator Superfamily
MI63_RS23270	COG1566	PFAM secretion protein HlyD family protein
MI63_RS23275	COG1309	transcriptional regulator
MI63_RS23280	COG1363	Peptidase, m42
MI63_RS23305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MI63_RS23315	COG1484	DNA-dependent DNA replication
MI63_RS23320	COG3611	Membrane attachment protein
MI63_RS23330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MI63_RS23335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MI63_RS23340	COG0237	dephospho-CoA kinase activity
MI63_RS23345	COG1971	Probably functions as a manganese efflux pump
MI63_RS23355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MI63_RS23355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MI63_RS23360	COG5002	protein histidine kinase activity
MI63_RS23365	COG0745	RESPONSE REGULATOR receiver
MI63_RS23385	COG0538	isocitrate dehydrogenase activity
MI63_RS23390	COG0372	Belongs to the citrate synthase family
MI63_RS23405	COG0628	permease
MI63_RS23410	COG3030	protein affecting phage T7 exclusion by the F plasmid
MI63_RS23435	COG1725	Transcriptional regulator
MI63_RS23440	COG0281	malic enzyme
MI63_RS23445	COG0587	DNA-directed DNA polymerase activity
MI63_RS23460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MI63_RS23480	COG4109	DRTGG domain
MI63_RS23495	COG0006	proline dipeptidase activity
MI63_RS23530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS23535	COG0662	Cupin 2, conserved barrel domain protein
MI63_RS23545	COG1476	TRANSCRIPTIONal
MI63_RS23560	COG1028	Short-chain dehydrogenase reductase Sdr
MI63_RS23565	COG0589	response to stress
MI63_RS23605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS23625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MI63_RS23630	COG0827	DNA restriction-modification system
MI63_RS23635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MI63_RS23640	COG3874	Sporulation protein YtfJ
MI63_RS23655	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MI63_RS23665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MI63_RS23680	COG1104	cysteine desulfurase activity
MI63_RS23690	COG0583	DNA-binding transcription factor activity
MI63_RS23695	COG0697	spore germination
MI63_RS23705	COG1956	GAF domain-containing protein
MI63_RS23710	COG0626	cystathionine gamma-synthase activity
MI63_RS23740	COG1595	DNA-templated transcription, initiation
MI63_RS23750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MI63_RS23755	COG0454	-acetyltransferase
MI63_RS23760	COG0517	IMP dehydrogenase activity
MI63_RS23765	COG0123	including yeast histone deacetylase and acetoin utilization protein
MI63_RS23775	COG0745	RESPONSE REGULATOR receiver
MI63_RS23785	COG0666	response to abiotic stimulus
MI63_RS23820	COG1609	Transcriptional regulator
MI63_RS23830	COG4851	CamS sex pheromone cAM373 precursor
MI63_RS23835	COG3118	belongs to the thioredoxin family
MI63_RS23845	COG2309	aminopeptidase activity
MI63_RS23865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS23880	COG1674	ftsk spoiiie
MI63_RS23890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MI63_RS23895	COG4848	Belongs to the UPF0354 family
MI63_RS23900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MI63_RS23905	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MI63_RS23910	COG1363	Peptidase, m42
MI63_RS23920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS23935	COG0510	thiamine kinase activity
MI63_RS23940	COG1523	belongs to the glycosyl hydrolase 13 family
MI63_RS23955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MI63_RS23960	COG1349	DNA-binding transcription factor activity
MI63_RS23965	COG1187	pseudouridine synthase activity
MI63_RS23970	COG2244	polysaccharide biosynthetic process
MI63_RS23975	COG2081	HI0933 family
MI63_RS23980	COG2814	Major facilitator Superfamily
MI63_RS23990	COG3832	glyoxalase III activity
MI63_RS24010	COG1329	Transcriptional regulator
MI63_RS24020	COG4975	Glucose uptake
MI63_RS24035	COG0314	molybdopterin synthase activity
MI63_RS24040	COG1763	Mo-molybdopterin cofactor biosynthetic process
MI63_RS24045	COG0303	'Molybdopterin
MI63_RS24055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MI63_RS24060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MI63_RS24080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MI63_RS24090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MI63_RS24135	COG2814	Major facilitator Superfamily
MI63_RS24140	COG0475	glutathione-regulated potassium exporter activity
MI63_RS24145	COG0490	domain, Protein
MI63_RS24150	COG0582	viral genome integration into host DNA
MI63_RS24160	COG1136	(ABC) transporter
MI63_RS24180	COG1242	4 iron, 4 sulfur cluster binding
MI63_RS24185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MI63_RS24190	COG1131	(ABC) transporter
MI63_RS24200	COG1794	racemase activity, acting on amino acids and derivatives
MI63_RS24220	COG2267	carboxylic ester hydrolase activity
MI63_RS24225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MI63_RS24230	COG0671	phosphoesterase, PA-phosphatase related
MI63_RS24235	COG0438	transferase activity, transferring glycosyl groups
MI63_RS24245	COG0521	Mo-molybdopterin cofactor biosynthetic process
MI63_RS24300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MI63_RS24305	COG5002	protein histidine kinase activity
MI63_RS24310	COG4191	Histidine kinase
MI63_RS24315	COG2267	carboxylic ester hydrolase activity
MI63_RS24335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MI63_RS24340	COG1116	anion transmembrane transporter activity
MI63_RS24345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MI63_RS24370	COG0494	nUDIX hydrolase
MI63_RS24400	COG0288	reversible hydration of carbon dioxide
MI63_RS24405	COG1271	oxidase subunit
MI63_RS24410	COG1294	oxidase, subunit
MI63_RS24430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS24455	COG1842	Phage shock protein A
MI63_RS24490	COG5002	protein histidine kinase activity
MI63_RS24495	COG0745	RESPONSE REGULATOR receiver
MI63_RS24520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MI63_RS24525	COG1597	lipid kinase activity
MI63_RS24560	COG0586	Pfam SNARE associated Golgi protein
MI63_RS24570	COG0577	efflux transmembrane transporter activity
MI63_RS24575	COG1136	(ABC) transporter
MI63_RS24585	COG0745	RESPONSE REGULATOR receiver
MI63_RS24590	COG2205	protein histidine kinase activity
MI63_RS24595	COG0577	efflux transmembrane transporter activity
MI63_RS24600	COG0577	efflux transmembrane transporter activity
MI63_RS24605	COG1136	(ABC) transporter
MI63_RS24625	COG2188	Transcriptional regulator
MI63_RS24645	COG3964	amidohydrolase
MI63_RS24675	COG4948	Mandelate Racemase Muconate Lactonizing
MI63_RS24685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MI63_RS24690	COG0596	Alpha beta hydrolase
MI63_RS24695	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MI63_RS24700	COG1169	isochorismate synthase
MI63_RS24705	COG1575	Belongs to the MenA family. Type 1 subfamily
MI63_RS24710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MI63_RS24735	COG0058	SHG alpha-glucan phosphorylase activity
MI63_RS24740	COG0297	glycogen (starch) synthase activity
MI63_RS24745	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MI63_RS24855	COG0544	peptidyl-prolyl cis-trans isomerase activity
MI63_RS24890	COG1285	pathogenesis
MI63_RS24895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MI63_RS24905	COG0166	Belongs to the GPI family
MI63_RS24915	COG2155	Conserved Protein
MI63_RS24920	COG1098	S1 RNA binding domain
MI63_RS24925	COG0436	Aminotransferase
MI63_RS24930	COG1522	sequence-specific DNA binding
MI63_RS24935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MI63_RS24940	COG2267	carboxylic ester hydrolase activity
MI63_RS24950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MI63_RS24970	COG5018	Exonuclease
MI63_RS24975	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MI63_RS24995	COG2050	protein possibly involved in aromatic compounds catabolism
MI63_RS25005	COG1268	BioY protein
MI63_RS25015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MI63_RS25020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MI63_RS25035	COG3584	3D domain protein
MI63_RS25050	COG1252	NADH dehydrogenase
MI63_RS25065	COG3708	Transcriptional regulator
MI63_RS25080	COG1683	Conserved Protein
MI63_RS25100	COG0316	Belongs to the HesB IscA family
MI63_RS25115	COG1252	NADH dehydrogenase
MI63_RS25125	COG2274	protein secretion by the type I secretion system
MI63_RS25130	COG0390	transport system, permease component
MI63_RS25135	COG2824	Alkylphosphonate utilization operon protein PhnA
MI63_RS25175	COG4837	Protein of unknown function (DUF1462)
MI63_RS25180	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MI63_RS25190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MI63_RS25195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MI63_RS25210	COG2249	NAD(P)H dehydrogenase (quinone) activity
MI63_RS25215	COG0647	UMP catabolic process
MI63_RS25225	COG2445	Protein of unknown function DUF86
MI63_RS25230	COG1494	fructose-1,6-bisphosphatase
MI63_RS25250	COG4470	Protein conserved in bacteria
MI63_RS25260	COG0789	Transcriptional regulator
MI63_RS25265	COG4377	Putative membrane peptidase family (DUF2324)
MI63_RS25290	COG0739	heme binding
MI63_RS25300	COG3377	Domain of unknown function (DUF1805)
MI63_RS25305	COG0737	Belongs to the 5'-nucleotidase family
MI63_RS25315	COG1695	Transcriptional regulator
MI63_RS25330	COG0719	Fe-S assembly protein
MI63_RS25335	COG0822	iron-sulfur transferase activity
MI63_RS25340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MI63_RS25345	COG0719	Fe-S assembly protein
MI63_RS25350	COG0396	ATPase activity
MI63_RS25355	COG1464	Belongs to the NlpA lipoprotein family
MI63_RS25360	COG1464	Belongs to the NlpA lipoprotein family
MI63_RS25365	COG2011	ABC-type metal ion transport system permease component
MI63_RS25370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MI63_RS25385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MI63_RS25390	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MI63_RS25400	COG1393	Belongs to the ArsC family
MI63_RS25450	COG0039	L-malate dehydrogenase activity
MI63_RS25475	COG1309	transcriptional regulator
MI63_RS25480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MI63_RS25485	COG1960	acyl-CoA dehydrogenase activity
MI63_RS25495	COG0183	Belongs to the thiolase family
MI63_RS25500	COG1024	Enoyl-CoA hydratase
MI63_RS25500	COG1250	3-hydroxyacyl-CoA dehydrogenase
MI63_RS25510	COG1686	Belongs to the peptidase S11 family
MI63_RS25525	COG0011	TIGRFAM Protein of
MI63_RS25530	COG0840	transmembrane signaling receptor activity
MI63_RS25550	COG2814	Major facilitator Superfamily
MI63_RS25555	COG0531	amino acid
MI63_RS25565	COG0706	membrane insertase activity
MI63_RS25575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MI63_RS25610	COG0586	Pfam SNARE associated Golgi protein
MI63_RS25620	COG1376	ErfK ybiS ycfS ynhG family protein
MI63_RS25625	COG0745	RESPONSE REGULATOR receiver
MI63_RS25630	COG5002	protein histidine kinase activity
MI63_RS25655	COG2151	metal-sulfur cluster biosynthetic enzyme
MI63_RS25660	COG3227	Zinc metalloprotease (Elastase)
MI63_RS25665	COG1741	Belongs to the pirin family
MI63_RS25680	COG0475	glutathione-regulated potassium exporter activity
MI63_RS25685	COG0490	domain, Protein
MI63_RS25695	COG1115	amino acid carrier protein
MI63_RS25700	COG0783	Belongs to the Dps family
MI63_RS25715	COG1611	Belongs to the LOG family
MI63_RS25730	COG2311	Membrane
MI63_RS25740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS25745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS25750	COG1115	amino acid carrier protein
MI63_RS25755	COG1115	amino acid carrier protein
MI63_RS25760	COG2910	NAD(P)H-binding
MI63_RS25775	COG0656	L-ascorbic acid biosynthetic process
MI63_RS25780	COG2814	Major facilitator Superfamily
MI63_RS25785	COG1733	regulation of RNA biosynthetic process
MI63_RS25795	COG1252	NADH dehydrogenase
MI63_RS25800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MI63_RS25805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MI63_RS25815	COG3290	protein histidine kinase activity
MI63_RS25815	COG0840	transmembrane signaling receptor activity
MI63_RS25825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MI63_RS25830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MI63_RS25845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MI63_RS25895	COG0557	exoribonuclease II activity
MI63_RS25900	COG1647	Serine aminopeptidase, S33
MI63_RS25905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MI63_RS25910	COG1346	cytolysis
MI63_RS26010	COG4695	Portal protein
MI63_RS26035	COG4974	Belongs to the 'phage' integrase family
MI63_RS26050	COG0149	triose-phosphate isomerase activity
MI63_RS26060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MI63_RS26075	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MI63_RS26100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MI63_RS26115	COG2323	membrane
MI63_RS26120	COG0740	serine-type endopeptidase activity
MI63_RS26125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MI63_RS26135	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MI63_RS26145	COG1051	belongs to the nudix hydrolase family
MI63_RS26155	COG0492	ferredoxin-NADP+ reductase activity
MI63_RS26160	COG0457	Tetratricopeptide repeat
MI63_RS26165	COG0110	maltose O-acetyltransferase activity
MI63_RS26185	COG1950	PFAM Membrane protein of
MI63_RS26195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MI63_RS26200	COG0556	nucleotide-excision repair
MI63_RS26220	COG0789	Transcriptional regulator
MI63_RS26245	COG2855	membrane
MI63_RS26250	COG0583	DNA-binding transcription factor activity
MI63_RS26260	COG0655	NAD(P)H dehydrogenase (quinone) activity
MI63_RS26265	COG0488	(ABC) transporter
MI63_RS26275	COG1132	(ABC) transporter
MI63_RS26280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MI63_RS26285	COG3409	Peptidoglycan-binding domain 1 protein
MI63_RS26285	COG0793	Belongs to the peptidase S41A family
MI63_RS26290	COG2177	Part of the ABC transporter FtsEX involved in
MI63_RS26295	COG2884	Cell division ATP-binding protein ftsE
MI63_RS26310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MI63_RS26315	COG0653	protein targeting
MI63_RS26320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MI63_RS26325	COG1278	Cold shock
MI63_RS26330	COG1040	competence protein
MI63_RS26340	COG0791	NLP P60 protein
MI63_RS26340	COG1388	LysM domain
MI63_RS26345	COG1733	regulation of RNA biosynthetic process
MI63_RS26355	COG1307	EDD domain protein, DegV family
MI63_RS26360	COG1739	Uncharacterized protein family UPF0029
MI63_RS26365	COG1316	TRANSCRIPTIONal
MI63_RS26370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MI63_RS26375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MI63_RS26380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MI63_RS26390	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MI63_RS26390	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MI63_RS26405	COG3394	polysaccharide catabolic process
MI63_RS26410	COG1486	melibiose metabolic process
MI63_RS26415	COG1447	Phosphotransferase system cellobiose-specific component IIA
MI63_RS26420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MI63_RS26430	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MI63_RS26435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MI63_RS26440	COG1447	Phosphotransferase system cellobiose-specific component IIA
MI63_RS26450	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MI63_RS26455	COG1301	dicarboxylic acid transport
MI63_RS26465	COG0346	lactoylglutathione lyase activity
MI63_RS26470	COG1511	domain protein
MI63_RS26475	COG0583	DNA-binding transcription factor activity
MI63_RS26480	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MI63_RS26495	COG1271	oxidase subunit
MI63_RS26500	COG1294	oxidase, subunit
MI63_RS26505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MI63_RS26515	COG1620	l-lactate permease
MI63_RS26525	COG2389	metal-binding protein
MI63_RS26535	COG1368	sulfuric ester hydrolase activity
MI63_RS26550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MI63_RS26570	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MI63_RS26575	COG1388	LysM domain
MI63_RS26575	COG3584	3D domain protein
MI63_RS26600	COG4715	Zinc finger, swim domain protein
MI63_RS26605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MI63_RS26645	COG0577	efflux transmembrane transporter activity
MI63_RS26650	COG1136	(ABC) transporter
MI63_RS26685	COG5002	protein histidine kinase activity
MI63_RS26690	COG0745	RESPONSE REGULATOR receiver
MI63_RS26695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MI63_RS26715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MI63_RS26720	COG1134	teichoic acid transport
MI63_RS26725	COG1682	transport, permease protein
MI63_RS26730	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MI63_RS26775	COG1609	Transcriptional regulator
MI63_RS26790	COG0739	heme binding
MI63_RS26805	COG3279	Response regulator of the LytR AlgR family
MI63_RS26810	COG4555	ABC transporter
MI63_RS26815	COG2385	sporulation resulting in formation of a cellular spore
MI63_RS26830	COG4836	Membrane
MI63_RS26835	COG1007	ATP synthesis coupled electron transport
MI63_RS26840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MI63_RS26845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MI63_RS26855	COG0839	Belongs to the complex I subunit 6 family
MI63_RS26870	COG0649	NAD binding
MI63_RS26875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MI63_RS26890	COG3300	MHYT domain
MI63_RS26890	COG5001	Diguanylate cyclase
MI63_RS26940	COG0356	it plays a direct role in the translocation of protons across the membrane
MI63_RS26975	COG0698	ribose 5-phosphate isomerase
MI63_RS26985	COG2190	(PTS) system
MI63_RS26990	COG2259	Doxx family
MI63_RS26995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MI63_RS27010	COG0009	L-threonylcarbamoyladenylate synthase
MI63_RS27025	COG2890	protein-(glutamine-N5) methyltransferase activity
MI63_RS27045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MI63_RS27050	COG1494	fructose-1,6-bisphosphatase
MI63_RS27070	COG4821	SIS domain
MI63_RS27080	COG3343	RNA polymerase activity
MI63_RS27090	COG1960	acyl-CoA dehydrogenase activity
MI63_RS27095	COG1960	acyl-CoA dehydrogenase activity
MI63_RS27100	COG1250	3-hydroxyacyl-CoA dehydrogenase
MI63_RS27105	COG0183	Belongs to the thiolase family
MI63_RS27110	COG0247	lactate metabolic process
MI63_RS27110	COG2181	nitrate reductase activity
MI63_RS27115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MI63_RS27125	COG3300	MHYT domain
MI63_RS27125	COG5001	Diguanylate cyclase
MI63_RS27140	COG2197	response regulator
MI63_RS27145	COG4585	Histidine kinase
MI63_RS27150	COG0842	Transport permease protein
MI63_RS27155	COG1131	(ABC) transporter
MI63_RS27160	COG0024	Methionine aminopeptidase
MI63_RS27175	COG2234	aminopeptidase activity
MI63_RS27195	COG1595	DNA-templated transcription, initiation
MI63_RS27200	COG0018	arginyl-trna synthetase
MI63_RS27205	COG4506	Protein conserved in bacteria
MI63_RS27210	COG1619	proteins homologs of microcin C7 resistance protein MccF
MI63_RS27230	COG0010	Belongs to the arginase family
MI63_RS27240	COG2814	Major facilitator Superfamily
MI63_RS27245	COG0789	Transcriptional regulator
MI63_RS27250	COG0584	glycerophosphoryl diester phosphodiesterase
MI63_RS27255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MI63_RS27265	COG1994	Peptidase M50
MI63_RS27275	COG1078	dGTPase activity
MI63_RS27280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MI63_RS27285	COG1120	ATPase activity
MI63_RS27290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS27295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MI63_RS27315	COG0095	Lipoate-protein ligase
MI63_RS27320	COG0280	phosphate acetyltransferase
MI63_RS27335	COG3773	Cell wall hydrolase
MI63_RS27345	COG2363	Small membrane protein
MI63_RS27355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MI63_RS27360	COG2233	PERMEase
MI63_RS27365	COG0561	phosphatase activity
MI63_RS27370	COG2814	Major facilitator Superfamily
MI63_RS27380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MI63_RS27385	COG1131	(ABC) transporter
MI63_RS27390	COG2755	lipolytic protein G-D-S-L family
MI63_RS27395	COG1609	Transcriptional regulator
MI63_RS27405	COG0460	homoserine dehydrogenase
MI63_RS27415	COG2873	o-acetylhomoserine
MI63_RS27425	COG1011	Hydrolase
MI63_RS27430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MI63_RS27440	COG2197	response regulator
MI63_RS27450	COG0351	phosphomethylpyrimidine kinase
MI63_RS27455	COG3706	GGDEF domain
MI63_RS27460	COG2879	small protein
MI63_RS27465	COG1966	Carbon starvation protein
MI63_RS27470	COG3279	Response regulator of the LytR AlgR family
MI63_RS27475	COG0477	Major facilitator Superfamily
MI63_RS27510	COG1607	acyl-coa hydrolase
MI63_RS27525	COG0488	(ABC) transporter
MI63_RS27550	COG0463	Glycosyl transferase, family 2
MI63_RS27555	COG1309	transcriptional regulator
MI63_RS27560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MI63_RS27565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MI63_RS27565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MI63_RS27570	COG0628	permease
MI63_RS27585	COG3279	Response regulator of the LytR AlgR family
MI63_RS27590	COG3275	phosphorelay sensor kinase activity
MI63_RS27595	COG2814	Major facilitator Superfamily
MI63_RS27600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MI63_RS27605	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MI63_RS27610	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MI63_RS27630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MI63_RS27635	COG1272	protein, Hemolysin III
MI63_RS27660	COG1164	Oligoendopeptidase f
MI63_RS27680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MI63_RS27685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MI63_RS27690	COG4853	Protein conserved in bacteria
MI63_RS27695	COG4863	YycH protein
MI63_RS27700	COG5002	protein histidine kinase activity
MI63_RS27705	COG0745	RESPONSE REGULATOR receiver
MI63_RS27735	COG0305	Participates in initiation and elongation during chromosome replication
MI63_RS27745	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MI63_RS27750	COG4241	membrane
MI63_RS27760	COG0629	single-stranded DNA binding
MI63_RS27770	COG0012	GTP binding
MI63_RS27775	COG4481	Protein conserved in bacteria
MI63_RS27780	COG0668	transmembrane transport
MI63_RS27790	COG1475	DNA binding
MI63_RS27795	COG1192	Involved in chromosome partitioning
MI63_RS27820	COG1847	R3H domain protein
MI63_RS27825	COG0706	membrane insertase activity
MI63_RS27835	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MI63_RS28135	COG0037	tRNA processing
MI63_RS28270	COG4956	integral membrane protein (PIN domain superfamily)
MI63_RS28350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MI63_RS28595	COG2610	gluconate transmembrane transporter activity
MI63_RS28600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MI63_RS28650	COG2011	ABC-type metal ion transport system permease component
MI63_RS28670	COG1464	Belongs to the NlpA lipoprotein family
MI63_RS28905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MI63_RS28905	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MI63_RS29025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MI63_RS29030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MI63_RS29070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MI63_RS29160	COG2376	Dihydroxyacetone kinase