locus-tag	class	description
AW20_RS00030	COG0457	Tetratricopeptide repeat
AW20_RS00055	COG4974	Belongs to the 'phage' integrase family
AW20_RS00065	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW20_RS00125	COG4974	Belongs to the 'phage' integrase family
AW20_RS00300	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW20_RS00305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW20_RS00310	COG1215	transferase activity, transferring glycosyl groups
AW20_RS00325	COG0671	phosphoesterase, PA-phosphatase related
AW20_RS00330	COG4196	transglutaminase domain protein
AW20_RS00355	COG2311	Membrane
AW20_RS00490	COG4962	Type ii secretion system protein e
AW20_RS00695	COG3344	reverse transcriptase
AW20_RS00775	COG3344	reverse transcriptase
AW20_RS00845	COG1115	amino acid carrier protein
AW20_RS00850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AW20_RS00860	COG3397	chitin binding
AW20_RS00885	COG4637	Psort location Cytoplasmic, score
AW20_RS00915	COG0514	ATP-dependent DNA helicase (RecQ)
AW20_RS00920	COG2105	PFAM AIG2 family protein
AW20_RS00935	COG3973	AAA domain
AW20_RS00985	COG0658	competence protein
AW20_RS00985	COG2333	competence protein COMEC
AW20_RS01015	COG2205	protein histidine kinase activity
AW20_RS01030	COG3397	chitin binding
AW20_RS01035	COG2153	protein acetylation
AW20_RS01040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AW20_RS01065	COG4175	Glycine betaine
AW20_RS01065	COG0517	IMP dehydrogenase activity
AW20_RS01070	COG4176	ABC-type proline glycine betaine transport system permease component
AW20_RS01105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW20_RS01105	COG0456	acetyltransferase
AW20_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS01120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW20_RS01125	COG0022	dehydrogenase e1 component
AW20_RS01130	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_RS01135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW20_RS01150	COG1959	2 iron, 2 sulfur cluster binding
AW20_RS01170	COG1349	DNA-binding transcription factor activity
AW20_RS01190	COG3284	Transcriptional regulator
AW20_RS01220	COG1309	transcriptional regulator
AW20_RS01225	COG3844	kynureninase activity
AW20_RS01230	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AW20_RS01235	COG3483	tryptophan 2,3-dioxygenase activity
AW20_RS01255	COG2959	enzyme of heme biosynthesis
AW20_RS01270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS01275	COG4129	membrane
AW20_RS01305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS01310	COG0697	spore germination
AW20_RS01320	COG0201	protein transport
AW20_RS01340	COG3227	Zinc metalloprotease (Elastase)
AW20_RS01345	COG1523	belongs to the glycosyl hydrolase 13 family
AW20_RS01360	COG0076	glutamate decarboxylase activity
AW20_RS01380	COG1011	Hydrolase
AW20_RS01405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_RS01445	COG0322	excinuclease ABC activity
AW20_RS01460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AW20_RS01515	COG3878	Protein conserved in bacteria
AW20_RS01550	COG1051	belongs to the nudix hydrolase family
AW20_RS01555	COG0592	DNA-directed DNA polymerase activity
AW20_RS01560	COG2816	NAD+ diphosphatase activity
AW20_RS01575	COG2223	nitrite transmembrane transporter activity
AW20_RS01610	COG0697	spore germination
AW20_RS01630	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_RS01645	COG2814	Major facilitator Superfamily
AW20_RS01675	COG0693	protein deglycase activity
AW20_RS01710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_RS01725	COG0604	alcohol dehydrogenase
AW20_RS01740	COG2205	protein histidine kinase activity
AW20_RS01750	COG1122	ATPase activity
AW20_RS01760	COG1794	racemase activity, acting on amino acids and derivatives
AW20_RS01765	COG1819	glycosyl
AW20_RS01775	COG5002	protein histidine kinase activity
AW20_RS01785	COG0561	phosphatase activity
AW20_RS01820	COG2124	cytochrome p450
AW20_RS01895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW20_RS01905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS01910	COG0460	homoserine dehydrogenase
AW20_RS01935	COG1136	(ABC) transporter
AW20_RS01965	COG0745	RESPONSE REGULATOR receiver
AW20_RS01975	COG3773	Cell wall hydrolase
AW20_RS02010	COG1063	alcohol dehydrogenase
AW20_RS02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS02045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW20_RS02065	COG2814	Major facilitator Superfamily
AW20_RS02090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW20_RS02090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW20_RS02130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AW20_RS02165	COG2318	DinB family
AW20_RS02175	COG0572	uridine kinase
AW20_RS02180	COG1247	-acetyltransferase
AW20_RS02190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW20_RS02195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AW20_RS02200	COG1024	Enoyl-CoA hydratase
AW20_RS02205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AW20_RS02210	COG0511	ligase activity, forming carbon-carbon bonds
AW20_RS02215	COG0439	Biotin carboxylase
AW20_RS02220	COG1960	acyl-CoA dehydrogenase activity
AW20_RS02235	COG1309	transcriptional regulator
AW20_RS02245	COG1131	(ABC) transporter
AW20_RS02260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_RS02265	COG1252	NADH dehydrogenase
AW20_RS02275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS02295	COG1309	transcriptional regulator
AW20_RS02315	COG1876	peptidase activity
AW20_RS02330	COG1476	TRANSCRIPTIONal
AW20_RS02335	COG0457	Tetratricopeptide repeat
AW20_RS02370	COG3718	enzyme involved in inositol metabolism
AW20_RS02375	COG0191	fructose-bisphosphate aldolase activity
AW20_RS02390	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS02400	COG0673	inositol 2-dehydrogenase activity
AW20_RS02405	COG2814	Major facilitator Superfamily
AW20_RS02410	COG1609	Transcriptional regulator
AW20_RS02415	COG0671	phosphoesterase, PA-phosphatase related
AW20_RS02420	COG2367	Beta-lactamase
AW20_RS02430	COG0768	penicillin binding
AW20_RS02440	COG1595	DNA-templated transcription, initiation
AW20_RS02455	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW20_RS02495	COG1846	Transcriptional regulator
AW20_RS02500	COG3961	Belongs to the TPP enzyme family
AW20_RS02505	COG2226	methyltransferase
AW20_RS02515	COG0500	methyltransferase
AW20_RS02515	COG3615	Tellurite resistance protein tehB
AW20_RS02520	COG1136	(ABC) transporter
AW20_RS02520	COG0577	efflux transmembrane transporter activity
AW20_RS02535	COG1309	transcriptional regulator
AW20_RS02565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS02585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AW20_RS02590	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW20_RS02595	COG2971	BadF BadG BcrA BcrD
AW20_RS02620	COG1649	PFAM Uncharacterised BCR, COG1649
AW20_RS02645	COG1595	DNA-templated transcription, initiation
AW20_RS02650	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AW20_RS02675	COG1396	sequence-specific DNA binding
AW20_RS02695	COG1132	(ABC) transporter
AW20_RS02700	COG1132	(ABC) transporter
AW20_RS02715	COG2258	MOSC domain
AW20_RS02720	COG0583	DNA-binding transcription factor activity
AW20_RS02735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW20_RS02740	COG0583	DNA-binding transcription factor activity
AW20_RS02785	COG0561	phosphatase activity
AW20_RS02790	COG0010	Belongs to the arginase family
AW20_RS02805	COG1278	Cold shock
AW20_RS02815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS02855	COG1247	-acetyltransferase
AW20_RS02890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS02935	COG2226	methyltransferase
AW20_RS02955	COG2814	Major facilitator Superfamily
AW20_RS02960	COG0596	Alpha beta hydrolase
AW20_RS02975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW20_RS02980	COG1187	pseudouridine synthase activity
AW20_RS02985	COG2329	Antibiotic biosynthesis monooxygenase
AW20_RS03005	COG1115	amino acid carrier protein
AW20_RS03015	COG2318	DinB family
AW20_RS03025	COG0776	regulation of translation
AW20_RS03040	COG2814	Major facilitator Superfamily
AW20_RS03045	COG3251	PFAM MbtH domain protein
AW20_RS03050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AW20_RS03055	COG3433	isochorismatase activity
AW20_RS03055	COG1535	isochorismatase
AW20_RS03060	COG1021	2,3-dihydroxybenzoate-AMP ligase
AW20_RS03065	COG1169	isochorismate synthase
AW20_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS03075	COG2223	nitrite transmembrane transporter activity
AW20_RS03105	COG0419	ATPase involved in DNA repair
AW20_RS03110	COG0420	3'-5' exonuclease activity
AW20_RS03125	COG1024	Enoyl-CoA hydratase
AW20_RS03130	COG1280	lysine exporter protein (LysE YggA)
AW20_RS03140	COG2084	Dehydrogenase
AW20_RS03145	COG1960	acyl-CoA dehydrogenase activity
AW20_RS03150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AW20_RS03155	COG2079	MmgE PrpD family protein
AW20_RS03160	COG0372	Belongs to the citrate synthase family
AW20_RS03165	COG4841	protein insertion into membrane
AW20_RS03170	COG2814	Major facilitator Superfamily
AW20_RS03175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_RS03175	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW20_RS03215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW20_RS03305	COG1787	Restriction endonuclease
AW20_RS03305	COG1715	Restriction endonuclease
AW20_RS03335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_RS03340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW20_RS03345	COG0671	phosphoesterase, PA-phosphatase related
AW20_RS03350	COG4326	sporulation control protein
AW20_RS03390	COG1509	lysine 2,3-aminomutase activity
AW20_RS03395	COG3829	transcription factor binding
AW20_RS03400	COG0456	acetyltransferase
AW20_RS03405	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW20_RS03410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AW20_RS03415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AW20_RS03420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW20_RS03435	COG5506	Protein of unknown function (DUF1694)
AW20_RS03440	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS03445	COG1253	flavin adenine dinucleotide binding
AW20_RS03480	COG1174	glycine betaine transport
AW20_RS03485	COG1125	glycine betaine transport
AW20_RS03485	COG0517	IMP dehydrogenase activity
AW20_RS03515	COG1070	Carbohydrate kinase
AW20_RS03520	COG1070	Carbohydrate kinase
AW20_RS03550	COG1064	alcohol dehydrogenase
AW20_RS03565	COG2197	response regulator
AW20_RS03570	COG4585	Histidine kinase
AW20_RS03570	COG2203	Gaf domain
AW20_RS03575	COG0668	transmembrane transport
AW20_RS03585	COG1051	belongs to the nudix hydrolase family
AW20_RS03610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_RS03615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS03635	COG0367	asparagine synthase
AW20_RS03640	COG0071	Belongs to the small heat shock protein (HSP20) family
AW20_RS03645	COG1999	signal sequence binding
AW20_RS03650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AW20_RS03655	COG1307	EDD domain protein, DegV family
AW20_RS03665	COG0805	protein transport
AW20_RS03675	COG1272	protein, Hemolysin III
AW20_RS03680	COG0204	Acyl-transferase
AW20_RS03685	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW20_RS03690	COG0768	penicillin binding
AW20_RS03705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_RS03725	COG0546	phosphoglycolate phosphatase activity
AW20_RS03740	COG1131	(ABC) transporter
AW20_RS03755	COG0456	acetyltransferase
AW20_RS03765	COG1794	racemase activity, acting on amino acids and derivatives
AW20_RS03770	COG1454	alcohol dehydrogenase
AW20_RS03775	COG2610	gluconate transmembrane transporter activity
AW20_RS03800	COG0733	neurotransmitter:sodium symporter activity
AW20_RS03815	COG3850	Histidine kinase
AW20_RS03815	COG5002	protein histidine kinase activity
AW20_RS03820	COG0745	RESPONSE REGULATOR receiver
AW20_RS03825	COG0471	metal ion transport
AW20_RS03830	COG1929	Belongs to the glycerate kinase type-1 family
AW20_RS03925	COG1674	ftsk spoiiie
AW20_RS03945	COG0017	Asparaginyl-tRNA synthetase
AW20_RS03965	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AW20_RS03990	COG0018	arginyl-trna synthetase
AW20_RS03995	COG2521	methyltransferase
AW20_RS03995	COG2136	Putative SAM-dependent methyltransferase
AW20_RS04010	COG1413	lyase activity
AW20_RS04030	COG0629	single-stranded DNA binding
AW20_RS04045	COG0488	(ABC) transporter
AW20_RS04050	COG1418	mRNA catabolic process
AW20_RS04065	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_RS04080	COG2359	stage V sporulation protein S
AW20_RS04115	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AW20_RS04120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW20_RS04125	COG2146	nitrite reductase [NAD(P)H] activity
AW20_RS04130	COG1587	Uroporphyrinogen-III synthase
AW20_RS04130	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AW20_RS04140	COG1648	precorrin-2 dehydrogenase activity
AW20_RS04155	COG2223	nitrite transmembrane transporter activity
AW20_RS04165	COG0314	molybdopterin synthase activity
AW20_RS04170	COG0303	'Molybdopterin
AW20_RS04175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_RS04180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AW20_RS04185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW20_RS04205	COG2181	nitrate reductase activity
AW20_RS04210	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AW20_RS04215	COG1140	nitrate reductase beta subunit
AW20_RS04220	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AW20_RS04235	COG0714	Associated with various cellular activities
AW20_RS04240	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AW20_RS04245	COG1305	Transglutaminase-like
AW20_RS04250	COG0386	Belongs to the glutathione peroxidase family
AW20_RS04275	COG1595	DNA-templated transcription, initiation
AW20_RS04280	COG0604	alcohol dehydrogenase
AW20_RS04290	COG0346	lactoylglutathione lyase activity
AW20_RS04315	COG2226	methyltransferase
AW20_RS04340	COG3874	Sporulation protein YtfJ
AW20_RS04390	COG0456	acetyltransferase
AW20_RS04415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS04420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS04425	COG1819	glycosyl
AW20_RS04440	COG4106	trans-aconitate 2-methyltransferase activity
AW20_RS04445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW20_RS04455	COG0561	phosphatase activity
AW20_RS04475	COG2211	Major facilitator Superfamily
AW20_RS04480	COG0154	amidase activity
AW20_RS04490	COG1876	peptidase activity
AW20_RS04500	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_RS04520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_RS04525	COG1114	Component of the transport system for branched-chain amino acids
AW20_RS04540	COG1253	flavin adenine dinucleotide binding
AW20_RS04545	COG2839	Protein conserved in bacteria
AW20_RS04550	COG0702	epimerase
AW20_RS04565	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_RS04570	COG1607	acyl-coa hydrolase
AW20_RS04575	COG3689	TIGRFAM TIGR03943 family protein
AW20_RS04580	COG0701	Predicted permease
AW20_RS04590	COG2244	polysaccharide biosynthetic process
AW20_RS04595	COG0586	Pfam SNARE associated Golgi protein
AW20_RS04600	COG1051	belongs to the nudix hydrolase family
AW20_RS04605	COG5337	Spore coat protein CotH
AW20_RS04615	COG0406	alpha-ribazole phosphatase activity
AW20_RS04630	COG4166	transmembrane transport
AW20_RS04640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW20_RS04650	COG0702	epimerase
AW20_RS04660	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW20_RS04660	COG3443	Belongs to the bacterial solute-binding protein 9 family
AW20_RS04725	COG0456	acetyltransferase
AW20_RS04730	COG0523	cobalamin synthesis protein
AW20_RS04735	COG4989	oxidoreductase activity
AW20_RS04745	COG1231	oxidoreductase activity
AW20_RS04755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW20_RS04770	COG0783	Belongs to the Dps family
AW20_RS04775	COG3949	Membrane
AW20_RS04795	COG0840	transmembrane signaling receptor activity
AW20_RS04820	COG2814	Major facilitator Superfamily
AW20_RS04825	COG0667	Aldo Keto reductase
AW20_RS04830	COG0640	Transcriptional regulator
AW20_RS04835	COG1404	Belongs to the peptidase S8 family
AW20_RS04840	COG2002	toxin-antitoxin pair type II binding
AW20_RS04880	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW20_RS04890	COG1279	arginine transmembrane transporter activity
AW20_RS04905	COG1082	Xylose isomerase domain protein TIM barrel
AW20_RS04920	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS04925	COG4264	IucA IucC family
AW20_RS04935	COG1247	-acetyltransferase
AW20_RS04940	COG1285	pathogenesis
AW20_RS04955	COG5002	protein histidine kinase activity
AW20_RS04960	COG0745	RESPONSE REGULATOR receiver
AW20_RS04970	COG1316	TRANSCRIPTIONal
AW20_RS04995	COG0460	homoserine dehydrogenase
AW20_RS05030	COG0300	oxidoreductase activity
AW20_RS05040	COG5002	protein histidine kinase activity
AW20_RS05045	COG0745	RESPONSE REGULATOR receiver
AW20_RS05065	COG0791	NLP P60 protein
AW20_RS05065	COG1388	LysM domain
AW20_RS05080	COG1686	Belongs to the peptidase S11 family
AW20_RS05100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AW20_RS05105	COG4988	ABC transporter
AW20_RS05110	COG1294	oxidase, subunit
AW20_RS05115	COG1271	oxidase subunit
AW20_RS05125	COG1846	Transcriptional regulator
AW20_RS05135	COG1942	4-Oxalocrotonate Tautomerase
AW20_RS05145	COG0583	DNA-binding transcription factor activity
AW20_RS05165	COG0411	ABC transporter
AW20_RS05175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_RS05180	COG2030	dehydratase
AW20_RS05185	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS05200	COG0523	cobalamin synthesis protein
AW20_RS05205	COG1231	oxidoreductase activity
AW20_RS05215	COG0628	permease
AW20_RS05230	COG0778	Nitroreductase
AW20_RS05235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AW20_RS05240	COG1959	2 iron, 2 sulfur cluster binding
AW20_RS05245	COG0583	DNA-binding transcription factor activity
AW20_RS05250	COG0697	spore germination
AW20_RS05260	COG4549	nuclear export factor GLE1
AW20_RS05265	COG2372	response to copper ion
AW20_RS05265	COG1276	copper resistance
AW20_RS05280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW20_RS05310	COG2132	Multicopper oxidase
AW20_RS05315	COG0006	proline dipeptidase activity
AW20_RS05335	COG4224	UPF0291 protein
AW20_RS05350	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AW20_RS05355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS05365	COG2390	Transcriptional regulator
AW20_RS05400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW20_RS05415	COG1914	H( )-stimulated, divalent metal cation uptake system
AW20_RS05435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS05470	COG1073	alpha beta
AW20_RS05490	COG0427	acetyl-CoA hydrolase
AW20_RS05495	COG3279	Response regulator of the LytR AlgR family
AW20_RS05505	COG3384	dioxygenase
AW20_RS05510	COG2814	Major facilitator Superfamily
AW20_RS05535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AW20_RS05545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW20_RS05550	COG0440	acetolactate synthase activity
AW20_RS05555	COG0028	Belongs to the TPP enzyme family
AW20_RS05560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_RS05570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW20_RS05585	COG2084	Dehydrogenase
AW20_RS05600	COG2323	membrane
AW20_RS05605	COG5566	PFAM Mor transcription activator
AW20_RS05615	COG0733	neurotransmitter:sodium symporter activity
AW20_RS05620	COG2244	polysaccharide biosynthetic process
AW20_RS05635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW20_RS05640	COG2223	nitrite transmembrane transporter activity
AW20_RS05655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AW20_RS05665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_RS05680	COG1966	Carbon starvation protein
AW20_RS05695	COG2814	Major facilitator Superfamily
AW20_RS05705	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_RS05710	COG1051	belongs to the nudix hydrolase family
AW20_RS05770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW20_RS05775	COG0784	Response regulator, receiver
AW20_RS05780	COG4191	Histidine kinase
AW20_RS05785	COG0281	malic enzyme
AW20_RS05790	COG1027	Aspartate ammonia-lyase
AW20_RS05800	COG0528	UMP kinase activity
AW20_RS05805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_RS05820	COG1131	(ABC) transporter
AW20_RS05855	COG2733	membrane
AW20_RS05890	COG0785	Cytochrome C biogenesis protein
AW20_RS05910	COG3340	Belongs to the peptidase S51 family
AW20_RS05940	COG0114	fumarate hydratase activity
AW20_RS05945	COG1757	Na H antiporter
AW20_RS05950	COG0438	transferase activity, transferring glycosyl groups
AW20_RS05950	COG1216	Glycosyl transferase, family 2
AW20_RS05960	COG0701	Predicted permease
AW20_RS05965	COG0523	cobalamin synthesis protein
AW20_RS05970	COG0697	spore germination
AW20_RS05975	COG1802	Transcriptional regulator
AW20_RS06005	COG0367	asparagine synthase
AW20_RS06035	COG0406	alpha-ribazole phosphatase activity
AW20_RS06045	COG1686	Belongs to the peptidase S11 family
AW20_RS06070	COG1234	tRNA 3'-trailer cleavage
AW20_RS06080	COG0725	ABC transporter, periplasmic molybdate-binding protein
AW20_RS06085	COG3842	ATPase activity
AW20_RS06090	COG0583	DNA-binding transcription factor activity
AW20_RS06115	COG2329	Antibiotic biosynthesis monooxygenase
AW20_RS06135	COG1309	transcriptional regulator
AW20_RS06160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW20_RS06165	COG4786	Flagellar basal body rod
AW20_RS06175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW20_RS06180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AW20_RS06190	COG1987	bacterial-type flagellum assembly
AW20_RS06195	COG1338	Plays a role in the flagellum-specific transport system
AW20_RS06205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_RS06205	COG1776	CheC inhibitor of MCP methylation
AW20_RS06220	COG0741	lytic transglycosylase activity
AW20_RS06225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AW20_RS06280	COG0463	Glycosyl transferase, family 2
AW20_RS06330	COG1157	protein secretion by the type III secretion system
AW20_RS06340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_RS06360	COG1558	bacterial-type flagellum-dependent cell motility
AW20_RS06365	COG1815	bacterial-type flagellum-dependent cell motility
AW20_RS06395	COG1256	bacterial-type flagellum assembly
AW20_RS06415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW20_RS06430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AW20_RS06430	COG1776	CheC inhibitor of MCP methylation
AW20_RS06440	COG2201	protein-glutamate methylesterase activity
AW20_RS06445	COG1360	Flagellar Motor Protein
AW20_RS06450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW20_RS06460	COG1923	regulation of RNA biosynthetic process
AW20_RS06515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AW20_RS06520	COG2323	membrane
AW20_RS06530	COG4978	Transcriptional regulator
AW20_RS06530	COG0789	Transcriptional regulator
AW20_RS06535	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW20_RS06540	COG0475	glutathione-regulated potassium exporter activity
AW20_RS06550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW20_RS06555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_RS06560	COG3162	membrane
AW20_RS06575	COG1280	lysine exporter protein (LysE YggA)
AW20_RS06615	COG0328	RNA-DNA hybrid ribonuclease activity
AW20_RS06635	COG0454	-acetyltransferase
AW20_RS06650	COG0438	transferase activity, transferring glycosyl groups
AW20_RS06655	COG1215	transferase activity, transferring glycosyl groups
AW20_RS06670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AW20_RS06695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW20_RS06735	COG0456	acetyltransferase
AW20_RS06745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW20_RS06750	COG2311	Membrane
AW20_RS06755	COG2233	PERMEase
AW20_RS06765	COG0024	Methionine aminopeptidase
AW20_RS06770	COG3173	Aminoglycoside phosphotransferase
AW20_RS06780	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AW20_RS06785	COG1199	ATP-dependent helicase activity
AW20_RS06795	COG0116	Belongs to the methyltransferase superfamily
AW20_RS06845	COG4499	WXG100 protein secretion system (Wss), protein YukC
AW20_RS06845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_RS06855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AW20_RS06860	COG3935	DnaD domain protein
AW20_RS06880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AW20_RS06880	COG1199	ATP-dependent helicase activity
AW20_RS06920	COG0438	transferase activity, transferring glycosyl groups
AW20_RS06925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW20_RS06940	COG1694	Mazg nucleotide pyrophosphohydrolase
AW20_RS06945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS06955	COG2738	Putative neutral zinc metallopeptidase
AW20_RS06970	COG4347	Protein of unknown function (DUF1405)
AW20_RS06980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AW20_RS07000	COG0457	Tetratricopeptide repeat
AW20_RS07005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW20_RS07025	COG0142	geranyltranstransferase activity
AW20_RS07035	COG0142	geranyltranstransferase activity
AW20_RS07050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW20_RS07125	COG0492	ferredoxin-NADP+ reductase activity
AW20_RS07145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AW20_RS07150	COG4862	establishment of competence for transformation
AW20_RS07170	COG1266	CAAX protease self-immunity
AW20_RS07175	COG0514	ATP-dependent DNA helicase (RecQ)
AW20_RS07180	COG4955	Helix-turn-helix domain
AW20_RS07185	COG1141	Ferredoxin
AW20_RS07190	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AW20_RS07205	COG2096	Adenosyltransferase
AW20_RS07210	COG5002	protein histidine kinase activity
AW20_RS07215	COG0745	RESPONSE REGULATOR receiver
AW20_RS07220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW20_RS07225	COG1333	cytochrome c biogenesis protein
AW20_RS07235	COG1187	pseudouridine synthase activity
AW20_RS07240	COG0700	Nucleoside recognition
AW20_RS07245	COG2715	membrane protein required for spore maturation
AW20_RS07250	COG1686	Belongs to the peptidase S11 family
AW20_RS07255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW20_RS07270	COG0392	lysyltransferase activity
AW20_RS07270	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AW20_RS07290	COG5002	protein histidine kinase activity
AW20_RS07295	COG0582	viral genome integration into host DNA
AW20_RS07305	COG1801	Protein of unknown function DUF72
AW20_RS07325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_RS07330	COG1392	Phosphate transport regulator
AW20_RS07335	COG0306	phosphate transporter
AW20_RS07340	COG0730	response to heat
AW20_RS07360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AW20_RS07360	COG1017	nitric oxide dioxygenase activity
AW20_RS07385	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AW20_RS07395	COG1114	Component of the transport system for branched-chain amino acids
AW20_RS07405	COG2197	response regulator
AW20_RS07410	COG4585	Histidine kinase
AW20_RS07415	COG4758	membrane
AW20_RS07430	COG1757	Na H antiporter
AW20_RS07450	COG0733	neurotransmitter:sodium symporter activity
AW20_RS07460	COG1648	precorrin-2 dehydrogenase activity
AW20_RS07480	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AW20_RS07485	COG0529	Catalyzes the synthesis of activated sulfate
AW20_RS07505	COG0019	diaminopimelate decarboxylase activity
AW20_RS07515	COG1368	sulfuric ester hydrolase activity
AW20_RS07520	COG1183	phosphatidylcholine synthase activity
AW20_RS07535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AW20_RS07570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AW20_RS07595	COG0473	3-isopropylmalate dehydrogenase activity
AW20_RS07605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AW20_RS07610	COG0440	acetolactate synthase activity
AW20_RS07615	COG0028	Belongs to the TPP enzyme family
AW20_RS07620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_RS07650	COG3874	Sporulation protein YtfJ
AW20_RS07655	COG4709	membrane
AW20_RS07660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW20_RS07665	COG1301	dicarboxylic acid transport
AW20_RS07675	COG1846	Transcriptional regulator
AW20_RS07690	COG1968	undecaprenyl-diphosphatase activity
AW20_RS07695	COG0534	Mate efflux family protein
AW20_RS07715	COG3173	Aminoglycoside phosphotransferase
AW20_RS07730	COG0716	FMN binding
AW20_RS07755	COG1696	Membrane protein involved in D-alanine export
AW20_RS07765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW20_RS07770	COG2070	2-Nitropropane dioxygenase
AW20_RS07775	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW20_RS07785	COG1335	isochorismatase
AW20_RS07795	COG1522	sequence-specific DNA binding
AW20_RS07810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW20_RS07815	COG1131	(ABC) transporter
AW20_RS07825	COG1131	(ABC) transporter
AW20_RS07830	COG1725	Transcriptional regulator
AW20_RS07835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AW20_RS07855	COG1780	Probably involved in ribonucleotide reductase function
AW20_RS07890	COG4873	Protein conserved in bacteria
AW20_RS07905	COG0720	synthase
AW20_RS07915	COG5002	protein histidine kinase activity
AW20_RS07925	COG2318	DinB family
AW20_RS07935	COG1846	Transcriptional regulator
AW20_RS07940	COG3852	Histidine kinase
AW20_RS07950	COG2861	carbohydrate metabolic process
AW20_RS07975	COG1349	DNA-binding transcription factor activity
AW20_RS08005	COG1840	ABC-type Fe3 transport system, periplasmic component
AW20_RS08020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW20_RS08030	COG3243	poly(R)-hydroxyalkanoic acid synthase
AW20_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS08055	COG2030	dehydratase
AW20_RS08065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AW20_RS08070	COG0861	Integral membrane protein TerC family
AW20_RS08075	COG2116	formate transmembrane transporter activity
AW20_RS08085	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AW20_RS08105	COG2186	Transcriptional regulator
AW20_RS08110	COG5002	protein histidine kinase activity
AW20_RS08115	COG0745	RESPONSE REGULATOR receiver
AW20_RS08125	COG3835	regulator
AW20_RS08130	COG0277	FAD linked oxidase domain protein
AW20_RS08135	COG0247	lactate metabolic process
AW20_RS08140	COG2340	Cysteine-rich secretory protein family
AW20_RS08150	COG0564	pseudouridine synthase activity
AW20_RS08160	COG2409	Drug exporters of the RND superfamily
AW20_RS08170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AW20_RS08175	COG1177	transmembrane transport
AW20_RS08180	COG1176	ABC-type spermidine putrescine transport system, permease component I
AW20_RS08185	COG3842	ATPase activity
AW20_RS08190	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS08225	COG0681	Belongs to the peptidase S26 family
AW20_RS08230	COG1686	Belongs to the peptidase S11 family
AW20_RS08240	COG2226	methyltransferase
AW20_RS08300	COG1476	TRANSCRIPTIONal
AW20_RS08310	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_RS08360	COG5634	Uncharacterized conserved protein (DUF2278)
AW20_RS08365	COG1620	l-lactate permease
AW20_RS08400	COG0512	Glutamine amidotransferase of anthranilate synthase
AW20_RS08400	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AW20_RS08415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_RS08420	COG5492	domain, Protein
AW20_RS08435	COG2382	esterase
AW20_RS08445	COG2153	protein acetylation
AW20_RS08490	COG1091	dTDP-4-dehydrorhamnose reductase activity
AW20_RS08505	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AW20_RS08525	COG0457	Tetratricopeptide repeat
AW20_RS08525	COG0463	Glycosyl transferase, family 2
AW20_RS08545	COG1216	Glycosyl transferase, family 2
AW20_RS08545	COG0463	Glycosyl transferase, family 2
AW20_RS08565	COG0564	pseudouridine synthase activity
AW20_RS08575	COG2357	RelA SpoT domain protein
AW20_RS08585	COG4116	CYTH
AW20_RS08590	COG2346	COG2346, Truncated hemoglobins
AW20_RS08605	COG1164	Oligoendopeptidase f
AW20_RS08615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_RS08620	COG4862	establishment of competence for transformation
AW20_RS08625	COG0861	Integral membrane protein TerC family
AW20_RS08645	COG4166	transmembrane transport
AW20_RS08650	COG0534	Mate efflux family protein
AW20_RS08655	COG4608	Belongs to the ABC transporter superfamily
AW20_RS08660	COG0444	Belongs to the ABC transporter superfamily
AW20_RS08665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW20_RS08670	COG0601	transmembrane transport
AW20_RS08675	COG4166	transmembrane transport
AW20_RS08685	COG0180	Tryptophanyl-tRNA synthetase
AW20_RS08695	COG5504	Zn-dependent protease
AW20_RS08700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AW20_RS08705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_RS08720	COG2267	carboxylic ester hydrolase activity
AW20_RS08730	COG0542	response to heat
AW20_RS08745	COG0561	phosphatase activity
AW20_RS08760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS08770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW20_RS08780	COG2996	Protein conserved in bacteria
AW20_RS08805	COG0004	ammonium transporteR
AW20_RS08810	COG0753	catalase activity
AW20_RS08820	COG0367	asparagine synthase
AW20_RS08845	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW20_RS08890	COG1074	ATP-dependent DNA helicase activity
AW20_RS08895	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AW20_RS08905	COG0398	Pfam SNARE associated Golgi protein
AW20_RS08910	COG4903	ComK protein
AW20_RS08940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AW20_RS08960	COG0697	spore germination
AW20_RS08965	COG0840	transmembrane signaling receptor activity
AW20_RS08970	COG0501	Belongs to the peptidase M48B family
AW20_RS08995	COG0745	RESPONSE REGULATOR receiver
AW20_RS09000	COG2205	protein histidine kinase activity
AW20_RS09015	COG2207	Transcriptional regulator
AW20_RS09015	COG3708	Transcriptional regulator
AW20_RS09020	COG1595	DNA-templated transcription, initiation
AW20_RS09030	COG1078	dGTPase activity
AW20_RS09080	COG3209	COG3209 Rhs family protein
AW20_RS09110	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS09120	COG0095	Lipoate-protein ligase
AW20_RS09125	COG1234	tRNA 3'-trailer cleavage
AW20_RS09160	COG1511	domain protein
AW20_RS09165	COG1309	transcriptional regulator
AW20_RS09210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AW20_RS09215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_RS09220	COG2329	Antibiotic biosynthesis monooxygenase
AW20_RS09225	COG3428	Bacterial PH domain
AW20_RS09230	COG3402	PFAM membrane-flanked domain
AW20_RS09285	COG3402	PFAM membrane-flanked domain
AW20_RS09295	COG1309	transcriptional regulator
AW20_RS09305	COG4473	ABC transporter
AW20_RS09310	COG1131	(ABC) transporter
AW20_RS09315	COG0537	adenosine 5'-monophosphoramidase activity
AW20_RS09320	COG4980	gas vesicle protein
AW20_RS09345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AW20_RS09350	COG3973	AAA domain
AW20_RS09360	COG0477	Major facilitator Superfamily
AW20_RS09365	COG0477	Major facilitator Superfamily
AW20_RS09405	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AW20_RS09415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AW20_RS09420	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW20_RS09440	COG2267	carboxylic ester hydrolase activity
AW20_RS09445	COG0457	Tetratricopeptide repeat
AW20_RS09450	COG0346	lactoylglutathione lyase activity
AW20_RS09455	COG0346	lactoylglutathione lyase activity
AW20_RS09460	COG2814	Major facilitator Superfamily
AW20_RS09465	COG1309	transcriptional regulator
AW20_RS09490	COG0420	3'-5' exonuclease activity
AW20_RS09550	COG0784	Response regulator, receiver
AW20_RS09550	COG2198	Histidine kinase
AW20_RS09550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_RS09550	COG2205	protein histidine kinase activity
AW20_RS09555	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AW20_RS09560	COG2208	phosphoserine phosphatase activity
AW20_RS09570	COG1191	sigma factor activity
AW20_RS09595	COG3237	CsbD-like
AW20_RS09645	COG3437	response regulator, receiver
AW20_RS09645	COG2770	Histidine kinase
AW20_RS09670	COG1959	2 iron, 2 sulfur cluster binding
AW20_RS09675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AW20_RS09690	COG2376	Dihydroxyacetone kinase
AW20_RS09710	COG1183	phosphatidylcholine synthase activity
AW20_RS09730	COG1309	transcriptional regulator
AW20_RS09735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW20_RS09735	COG3320	Male sterility
AW20_RS09785	COG0477	Major facilitator Superfamily
AW20_RS09825	COG0305	Participates in initiation and elongation during chromosome replication
AW20_RS09840	COG0789	Transcriptional regulator
AW20_RS09840	COG4978	Transcriptional regulator
AW20_RS09870	COG3181	Tripartite tricarboxylate transporter family receptor
AW20_RS09875	COG4565	transcriptional regulatory protein
AW20_RS09880	COG3290	protein histidine kinase activity
AW20_RS09885	COG0477	Major facilitator Superfamily
AW20_RS09915	COG4608	Belongs to the ABC transporter superfamily
AW20_RS09925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW20_RS09930	COG0601	transmembrane transport
AW20_RS09970	COG3938	Belongs to the proline racemase family
AW20_RS09990	COG1363	Peptidase, m42
AW20_RS10010	COG1024	Enoyl-CoA hydratase
AW20_RS10025	COG1696	Membrane protein involved in D-alanine export
AW20_RS10040	COG4196	transglutaminase domain protein
AW20_RS10045	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_RS10055	COG2244	polysaccharide biosynthetic process
AW20_RS10060	COG0653	protein targeting
AW20_RS10080	COG0659	secondary active sulfate transmembrane transporter activity
AW20_RS10095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW20_RS10110	COG0561	phosphatase activity
AW20_RS10125	COG3527	Alpha-acetolactate decarboxylase
AW20_RS10130	COG0028	Belongs to the TPP enzyme family
AW20_RS10160	COG0189	ligase activity
AW20_RS10175	COG1126	abc transporter atp-binding protein
AW20_RS10180	COG0765	amino acid transport
AW20_RS10185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_RS10195	COG1132	(ABC) transporter
AW20_RS10205	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS10215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AW20_RS10220	COG0531	amino acid
AW20_RS10235	COG0693	protein deglycase activity
AW20_RS10245	COG2211	Major facilitator Superfamily
AW20_RS10250	COG4533	DNA binding
AW20_RS10255	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_RS10265	COG1733	regulation of RNA biosynthetic process
AW20_RS10270	COG2814	Major facilitator Superfamily
AW20_RS10275	COG1309	transcriptional regulator
AW20_RS10280	COG2076	Multidrug Resistance protein
AW20_RS10295	COG1522	sequence-specific DNA binding
AW20_RS10300	COG0697	spore germination
AW20_RS10315	COG2259	Doxx family
AW20_RS10325	COG1263	PTS System
AW20_RS10325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_RS10335	COG1737	Transcriptional regulator
AW20_RS10345	COG0475	glutathione-regulated potassium exporter activity
AW20_RS10350	COG0531	amino acid
AW20_RS10385	COG0586	Pfam SNARE associated Golgi protein
AW20_RS10420	COG3546	catalase activity
AW20_RS10425	COG1114	Component of the transport system for branched-chain amino acids
AW20_RS10440	COG5522	Integral membrane protein (intg_mem_TP0381)
AW20_RS10450	COG1136	(ABC) transporter
AW20_RS10455	COG0577	efflux transmembrane transporter activity
AW20_RS10460	COG1388	LysM domain
AW20_RS10460	COG3584	3D domain protein
AW20_RS10480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW20_RS10485	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW20_RS10490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW20_RS10490	COG3711	transcriptional antiterminator
AW20_RS10505	COG1283	sodium-dependent phosphate transmembrane transporter activity
AW20_RS10510	COG0604	alcohol dehydrogenase
AW20_RS10515	COG1316	TRANSCRIPTIONal
AW20_RS10525	COG0730	response to heat
AW20_RS10530	COG2210	Belongs to the sulfur carrier protein TusA family
AW20_RS10540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_RS10545	COG0425	Belongs to the sulfur carrier protein TusA family
AW20_RS10550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_RS10550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS10555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_RS10555	COG0425	Belongs to the sulfur carrier protein TusA family
AW20_RS10560	COG1937	Protein conserved in bacteria
AW20_RS10565	COG0446	pyridine nucleotide-disulphide oxidoreductase
AW20_RS10590	COG2719	SpoVR family
AW20_RS10595	COG0778	Nitroreductase
AW20_RS10635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AW20_RS10640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_RS10650	COG1609	Transcriptional regulator
AW20_RS10655	COG1263	PTS System
AW20_RS10655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_RS10660	COG1621	beta-fructofuranosidase activity
AW20_RS10665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW20_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS10685	COG2252	PERMEase
AW20_RS10700	COG1846	Transcriptional regulator
AW20_RS10705	COG2814	Major facilitator Superfamily
AW20_RS10710	COG2205	protein histidine kinase activity
AW20_RS10755	COG0351	phosphomethylpyrimidine kinase
AW20_RS10760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_RS10770	COG2104	thiamine diphosphate biosynthetic process
AW20_RS10775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_RS10780	COG0352	thiamine-phosphate diphosphorylase activity
AW20_RS10785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW20_RS10790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_RS10795	COG1116	anion transmembrane transporter activity
AW20_RS10800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AW20_RS10825	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AW20_RS10940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW20_RS10950	COG0581	inorganic phosphate transmembrane transporter activity
AW20_RS10955	COG0573	inorganic phosphate transmembrane transporter activity
AW20_RS10960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW20_RS10965	COG1918	ferrous iron import across plasma membrane
AW20_RS10965	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW20_RS10970	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW20_RS10975	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AW20_RS10990	COG0531	amino acid
AW20_RS10995	COG0697	spore germination
AW20_RS11000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_RS11015	COG4990	cell redox homeostasis
AW20_RS11020	COG0833	amino acid
AW20_RS11025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AW20_RS11030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AW20_RS11045	COG0475	glutathione-regulated potassium exporter activity
AW20_RS11045	COG0569	domain protein
AW20_RS11070	COG2252	PERMEase
AW20_RS11090	COG1114	Component of the transport system for branched-chain amino acids
AW20_RS11095	COG3104	oligopeptide transport
AW20_RS11110	COG1476	TRANSCRIPTIONal
AW20_RS11115	COG1388	LysM domain
AW20_RS11115	COG3584	3D domain protein
AW20_RS11120	COG0840	transmembrane signaling receptor activity
AW20_RS11125	COG1968	undecaprenyl-diphosphatase activity
AW20_RS11150	COG3568	Endonuclease Exonuclease Phosphatase
AW20_RS11165	COG1063	alcohol dehydrogenase
AW20_RS11190	COG1879	ABC-type sugar transport system periplasmic component
AW20_RS11195	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW20_RS11210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AW20_RS11215	COG1609	Transcriptional regulator
AW20_RS11230	COG1846	Transcriptional regulator
AW20_RS11235	COG2271	Major facilitator Superfamily
AW20_RS11245	COG4608	Belongs to the ABC transporter superfamily
AW20_RS11250	COG0601	transmembrane transport
AW20_RS11260	COG0747	negative chemotaxis
AW20_RS11275	COG0659	secondary active sulfate transmembrane transporter activity
AW20_RS11290	COG5002	protein histidine kinase activity
AW20_RS11295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AW20_RS11300	COG2378	regulation of single-species biofilm formation
AW20_RS11325	COG0833	amino acid
AW20_RS11330	COG0765	amino acid transport
AW20_RS11335	COG0765	amino acid transport
AW20_RS11340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_RS11345	COG1126	abc transporter atp-binding protein
AW20_RS11350	COG1115	amino acid carrier protein
AW20_RS11355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW20_RS11365	COG0697	spore germination
AW20_RS11380	COG0366	Alpha amylase catalytic
AW20_RS11385	COG1263	PTS System
AW20_RS11385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_RS11390	COG2188	Transcriptional regulator
AW20_RS11395	COG0531	amino acid
AW20_RS11415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_RS11420	COG0714	Associated with various cellular activities
AW20_RS11425	COG4548	von Willebrand factor, type A
AW20_RS11440	COG0156	8-amino-7-oxononanoate synthase activity
AW20_RS11445	COG2226	methyltransferase
AW20_RS11455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS11460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS11465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS11470	COG3104	oligopeptide transport
AW20_RS11485	COG1620	l-lactate permease
AW20_RS11490	COG1027	Aspartate ammonia-lyase
AW20_RS11495	COG1253	flavin adenine dinucleotide binding
AW20_RS11500	COG0346	lactoylglutathione lyase activity
AW20_RS11505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS11510	COG1316	TRANSCRIPTIONal
AW20_RS11515	COG2720	vancomycin resistance protein
AW20_RS11535	COG3227	Zinc metalloprotease (Elastase)
AW20_RS11545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AW20_RS11550	COG2217	Heavy metal translocating P-type atpase
AW20_RS11555	COG0640	Transcriptional regulator
AW20_RS11560	COG0531	amino acid
AW20_RS11575	COG2427	Protein of unknown function (DUF1641)
AW20_RS11580	COG3383	formate dehydrogenase (NAD+) activity
AW20_RS11585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW20_RS11590	COG0456	acetyltransferase
AW20_RS11590	COG0454	-acetyltransferase
AW20_RS11600	COG0745	RESPONSE REGULATOR receiver
AW20_RS11605	COG5002	protein histidine kinase activity
AW20_RS11615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS11630	COG0281	malic enzyme
AW20_RS11635	COG3493	citrate carrier protein
AW20_RS11640	COG4565	transcriptional regulatory protein
AW20_RS11645	COG3290	protein histidine kinase activity
AW20_RS11655	COG4990	cell redox homeostasis
AW20_RS11665	COG5002	protein histidine kinase activity
AW20_RS11670	COG0745	RESPONSE REGULATOR receiver
AW20_RS11675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AW20_RS11685	COG0395	ABC-type sugar transport system, permease component
AW20_RS11690	COG1175	transmembrane transport
AW20_RS11695	COG3842	ATPase activity
AW20_RS11700	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AW20_RS11720	COG2851	Citrate transporter
AW20_RS11730	COG3290	protein histidine kinase activity
AW20_RS11740	COG2268	Band 7 protein
AW20_RS11745	COG1585	Membrane protein implicated in regulation of membrane protease activity
AW20_RS11755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW20_RS11780	COG2766	serine protein kinase
AW20_RS11795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AW20_RS11805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AW20_RS11820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AW20_RS11935	COG0735	belongs to the Fur family
AW20_RS11940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AW20_RS11960	COG4555	ABC transporter
AW20_RS11970	COG0067	glutamate synthase
AW20_RS11970	COG0069	glutamate synthase activity
AW20_RS11970	COG0070	glutamate synthase
AW20_RS11975	COG4129	membrane
AW20_RS11980	COG1132	(ABC) transporter
AW20_RS12005	COG1194	a g-specific adenine glycosylase
AW20_RS12010	COG1988	membrane-bound metal-dependent
AW20_RS12040	COG1090	epimerase
AW20_RS12045	COG1228	amidohydrolase
AW20_RS12065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AW20_RS12085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW20_RS12085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AW20_RS12100	COG0463	Glycosyl transferase, family 2
AW20_RS12115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_RS12120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_RS12120	COG1263	PTS System
AW20_RS12155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AW20_RS12160	COG0833	amino acid
AW20_RS12170	COG3829	transcription factor binding
AW20_RS12180	COG0101	tRNA pseudouridine synthase activity
AW20_RS12405	COG1484	DNA-dependent DNA replication
AW20_RS12440	COG1396	sequence-specific DNA binding
AW20_RS12455	COG1396	sequence-specific DNA binding
AW20_RS12460	COG0582	viral genome integration into host DNA
AW20_RS12465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW20_RS12470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW20_RS12495	COG0535	radical SAM domain protein
AW20_RS12505	COG0387	Pfam Sodium calcium exchanger
AW20_RS12510	COG3871	stress protein (general stress protein 26)
AW20_RS12525	COG0586	Pfam SNARE associated Golgi protein
AW20_RS12545	COG0697	spore germination
AW20_RS12550	COG2217	Heavy metal translocating P-type atpase
AW20_RS12555	COG1295	ribonuclease BN
AW20_RS12565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AW20_RS12580	COG3853	Toxic anion resistance protein (TelA)
AW20_RS12590	COG0861	Integral membrane protein TerC family
AW20_RS12595	COG2310	stress, protein
AW20_RS12600	COG2310	stress, protein
AW20_RS12605	COG2310	stress, protein
AW20_RS12620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW20_RS12635	COG2270	Major facilitator Superfamily
AW20_RS12680	COG0488	(ABC) transporter
AW20_RS12685	COG1116	anion transmembrane transporter activity
AW20_RS12695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_RS12710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AW20_RS12740	COG1263	PTS System
AW20_RS12740	COG2190	(PTS) system
AW20_RS12740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_RS12745	COG0366	Alpha amylase catalytic
AW20_RS12750	COG0840	transmembrane signaling receptor activity
AW20_RS12755	COG0840	transmembrane signaling receptor activity
AW20_RS12765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_RS12770	COG0765	amino acid transport
AW20_RS12780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_RS12780	COG0723	plastoquinol--plastocyanin reductase activity
AW20_RS12785	COG2814	Major facilitator Superfamily
AW20_RS12790	COG3541	Predicted nucleotidyltransferase
AW20_RS12810	COG5002	protein histidine kinase activity
AW20_RS12845	COG0166	Belongs to the GPI family
AW20_RS12865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS12870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS12875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS12895	COG0450	alkyl hydroperoxide reductase
AW20_RS12910	COG1473	amidohydrolase
AW20_RS12940	COG4807	Protein conserved in bacteria
AW20_RS12950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW20_RS12955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AW20_RS12960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS12975	COG2309	aminopeptidase activity
AW20_RS12980	COG2076	Multidrug Resistance protein
AW20_RS12985	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS12995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW20_RS13000	COG0546	phosphoglycolate phosphatase activity
AW20_RS13005	COG1597	lipid kinase activity
AW20_RS13030	COG1846	Transcriptional regulator
AW20_RS13050	COG1464	Belongs to the NlpA lipoprotein family
AW20_RS13055	COG2011	ABC-type metal ion transport system permease component
AW20_RS13060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW20_RS13065	COG1335	isochorismatase
AW20_RS13085	COG4851	CamS sex pheromone cAM373 precursor
AW20_RS13095	COG0210	DNA helicase
AW20_RS13120	COG0151	Belongs to the GarS family
AW20_RS13130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AW20_RS13140	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AW20_RS13155	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AW20_RS13165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AW20_RS13170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AW20_RS13175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AW20_RS13200	COG0745	RESPONSE REGULATOR receiver
AW20_RS13205	COG2205	protein histidine kinase activity
AW20_RS13220	COG1968	undecaprenyl-diphosphatase activity
AW20_RS13260	COG2226	methyltransferase
AW20_RS13290	COG5002	protein histidine kinase activity
AW20_RS13300	COG2252	PERMEase
AW20_RS13320	COG1266	CAAX protease self-immunity
AW20_RS13335	COG0488	(ABC) transporter
AW20_RS13345	COG0456	acetyltransferase
AW20_RS13350	COG1214	PFAM Peptidase M22, glycoprotease
AW20_RS13355	COG0802	atpase or kinase
AW20_RS13450	COG2183	response to ionizing radiation
AW20_RS13455	COG2337	Toxic component of a toxin-antitoxin (TA) module
AW20_RS13460	COG0864	Transcriptional regulator
AW20_RS13465	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AW20_RS13470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AW20_RS13480	COG0457	Tetratricopeptide repeat
AW20_RS13480	COG0705	Rhomboid family
AW20_RS13485	COG4294	response to UV
AW20_RS13495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AW20_RS13510	COG2814	Major facilitator Superfamily
AW20_RS13520	COG0179	Fumarylacetoacetate (FAA) hydrolase
AW20_RS13525	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AW20_RS13550	COG4608	Belongs to the ABC transporter superfamily
AW20_RS13555	COG0444	Belongs to the ABC transporter superfamily
AW20_RS13565	COG0601	transmembrane transport
AW20_RS13570	COG0747	negative chemotaxis
AW20_RS13585	COG0488	(ABC) transporter
AW20_RS13610	COG5298	Protein conserved in bacteria
AW20_RS13615	COG0084	hydrolase, TatD family'
AW20_RS13630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS13640	COG1609	Transcriptional regulator
AW20_RS13650	COG0204	Acyl-transferase
AW20_RS13660	COG0697	spore germination
AW20_RS13665	COG0583	DNA-binding transcription factor activity
AW20_RS13680	COG1910	domain protein
AW20_RS13695	COG4149	molybdate abc transporter
AW20_RS13715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_RS13720	COG0656	L-ascorbic acid biosynthetic process
AW20_RS13725	COG4166	transmembrane transport
AW20_RS13730	COG4166	transmembrane transport
AW20_RS13745	COG2207	Transcriptional regulator
AW20_RS13755	COG4166	transmembrane transport
AW20_RS13760	COG4608	Belongs to the ABC transporter superfamily
AW20_RS13765	COG0444	Belongs to the ABC transporter superfamily
AW20_RS13770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AW20_RS13775	COG0601	transmembrane transport
AW20_RS13800	COG2271	Major facilitator Superfamily
AW20_RS13805	COG0277	FAD linked oxidase domain protein
AW20_RS13815	COG0604	alcohol dehydrogenase
AW20_RS13820	COG1464	Belongs to the NlpA lipoprotein family
AW20_RS13825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW20_RS13830	COG2011	ABC-type metal ion transport system permease component
AW20_RS13870	COG4946	Tricorn protease homolog
AW20_RS13870	COG0823	Involved in the tonB-independent uptake of proteins
AW20_RS13870	COG1506	peptidase
AW20_RS13875	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AW20_RS13895	COG0596	Alpha beta hydrolase
AW20_RS13900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AW20_RS13915	COG4856	YbbR-like protein
AW20_RS13920	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AW20_RS14005	COG0726	polysaccharide deacetylase
AW20_RS14010	COG2194	sulfuric ester hydrolase activity
AW20_RS14020	COG0489	protein tyrosine kinase activity
AW20_RS14025	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_RS14050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW20_RS14085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AW20_RS14095	COG0024	Methionine aminopeptidase
AW20_RS14105	COG0201	protein transport
AW20_RS14165	COG0255	Belongs to the universal ribosomal protein uL29 family
AW20_RS14235	COG1358	cellular component organization or biogenesis
AW20_RS14240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AW20_RS14250	COG2813	Specifically methylates the guanine in position
AW20_RS14270	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AW20_RS14275	COG0250	Participates in transcription elongation, termination and antitermination
AW20_RS14280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW20_RS14295	COG3688	RNA-binding protein containing a PIN domain
AW20_RS14300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW20_RS14315	COG1045	serine acetyltransferase
AW20_RS14335	COG4956	integral membrane protein (PIN domain superfamily)
AW20_RS14345	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AW20_RS14350	COG0542	response to heat
AW20_RS14360	COG3880	PFAM UvrB UvrC protein
AW20_RS14390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AW20_RS14395	COG1396	sequence-specific DNA binding
AW20_RS14400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AW20_RS14405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AW20_RS14410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AW20_RS14415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AW20_RS14420	COG0512	Glutamine amidotransferase of anthranilate synthase
AW20_RS14425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AW20_RS14430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW20_RS14445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AW20_RS14455	COG0037	tRNA processing
AW20_RS14460	COG2208	phosphoserine phosphatase activity
AW20_RS14475	COG1098	S1 RNA binding domain
AW20_RS14495	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AW20_RS14500	COG3956	TIGRFAM MazG family protein
AW20_RS14505	COG2244	polysaccharide biosynthetic process
AW20_RS14510	COG2002	toxin-antitoxin pair type II binding
AW20_RS14515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AW20_RS14545	COG0251	oxidation-reduction process
AW20_RS14550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AW20_RS14565	COG4466	Protein conserved in bacteria
AW20_RS14580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW20_RS14585	COG0084	hydrolase, TatD family'
AW20_RS14590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_RS14590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_RS14595	COG2002	toxin-antitoxin pair type II binding
AW20_RS14600	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AW20_RS14610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AW20_RS14620	COG1774	PSP1 C-terminal conserved region
AW20_RS14625	COG0470	DNA polymerase III
AW20_RS14635	COG1982	Orn Lys Arg decarboxylase major
AW20_RS14690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AW20_RS14695	COG0590	tRNA wobble adenosine to inosine editing
AW20_RS14705	COG1335	isochorismatase
AW20_RS14710	COG1428	Deoxynucleoside kinase
AW20_RS14715	COG1428	Deoxynucleoside kinase
AW20_RS14745	COG1686	Belongs to the peptidase S11 family
AW20_RS14750	COG0517	IMP dehydrogenase activity
AW20_RS14750	COG0516	GMP reductase activity
AW20_RS14785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW20_RS14790	COG0187	DNA topoisomerase II activity
AW20_RS14800	COG2501	S4 domain
AW20_RS14805	COG0592	DNA-directed DNA polymerase activity
AW20_RS14815	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AW20_RS14825	COG0706	membrane insertase activity
AW20_RS14830	COG1847	R3H domain protein
AW20_RS14855	COG1192	Involved in chromosome partitioning
AW20_RS14860	COG1475	DNA binding
AW20_RS14870	COG0668	transmembrane transport
AW20_RS14875	COG4481	Protein conserved in bacteria
AW20_RS14880	COG0012	GTP binding
AW20_RS14890	COG0629	single-stranded DNA binding
AW20_RS14900	COG4241	membrane
AW20_RS14905	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AW20_RS14915	COG0305	Participates in initiation and elongation during chromosome replication
AW20_RS14945	COG0745	RESPONSE REGULATOR receiver
AW20_RS14950	COG5002	protein histidine kinase activity
AW20_RS14955	COG4863	YycH protein
AW20_RS14960	COG4853	Protein conserved in bacteria
AW20_RS14965	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AW20_RS14970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW20_RS14990	COG1164	Oligoendopeptidase f
AW20_RS14995	COG0516	GMP reductase activity
AW20_RS15015	COG1272	protein, Hemolysin III
AW20_RS15020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW20_RS15040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW20_RS15045	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AW20_RS15050	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW20_RS15055	COG2814	Major facilitator Superfamily
AW20_RS15060	COG3275	phosphorelay sensor kinase activity
AW20_RS15065	COG3279	Response regulator of the LytR AlgR family
AW20_RS15080	COG0628	permease
AW20_RS15085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW20_RS15085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AW20_RS15090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AW20_RS15095	COG1309	transcriptional regulator
AW20_RS15100	COG0463	Glycosyl transferase, family 2
AW20_RS15130	COG0488	(ABC) transporter
AW20_RS15145	COG1607	acyl-coa hydrolase
AW20_RS15155	COG0840	transmembrane signaling receptor activity
AW20_RS15180	COG0477	Major facilitator Superfamily
AW20_RS15185	COG3279	Response regulator of the LytR AlgR family
AW20_RS15190	COG1966	Carbon starvation protein
AW20_RS15195	COG2879	small protein
AW20_RS15200	COG3706	GGDEF domain
AW20_RS15205	COG0351	phosphomethylpyrimidine kinase
AW20_RS15215	COG2197	response regulator
AW20_RS15225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AW20_RS15230	COG1011	Hydrolase
AW20_RS15240	COG2873	o-acetylhomoserine
AW20_RS15250	COG0460	homoserine dehydrogenase
AW20_RS15260	COG1609	Transcriptional regulator
AW20_RS15265	COG2755	lipolytic protein G-D-S-L family
AW20_RS15270	COG1131	(ABC) transporter
AW20_RS15275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW20_RS15285	COG2814	Major facilitator Superfamily
AW20_RS15290	COG0561	phosphatase activity
AW20_RS15295	COG2233	PERMEase
AW20_RS15310	COG2363	Small membrane protein
AW20_RS15320	COG3773	Cell wall hydrolase
AW20_RS15335	COG0280	phosphate acetyltransferase
AW20_RS15340	COG0095	Lipoate-protein ligase
AW20_RS15370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS15375	COG1120	ATPase activity
AW20_RS15380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS15385	COG1078	dGTPase activity
AW20_RS15395	COG1994	Peptidase M50
AW20_RS15405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AW20_RS15410	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_RS15415	COG0789	Transcriptional regulator
AW20_RS15420	COG2814	Major facilitator Superfamily
AW20_RS15430	COG0010	Belongs to the arginase family
AW20_RS15450	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW20_RS15455	COG4506	Protein conserved in bacteria
AW20_RS15460	COG0018	arginyl-trna synthetase
AW20_RS15465	COG1595	DNA-templated transcription, initiation
AW20_RS15485	COG2234	aminopeptidase activity
AW20_RS15505	COG0024	Methionine aminopeptidase
AW20_RS15510	COG1131	(ABC) transporter
AW20_RS15515	COG0842	Transport permease protein
AW20_RS15520	COG4585	Histidine kinase
AW20_RS15525	COG2197	response regulator
AW20_RS15540	COG5001	Diguanylate cyclase
AW20_RS15540	COG3300	MHYT domain
AW20_RS15550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AW20_RS15555	COG0247	lactate metabolic process
AW20_RS15555	COG2181	nitrate reductase activity
AW20_RS15560	COG0183	Belongs to the thiolase family
AW20_RS15565	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW20_RS15570	COG1960	acyl-CoA dehydrogenase activity
AW20_RS15585	COG3343	RNA polymerase activity
AW20_RS15595	COG4821	SIS domain
AW20_RS15615	COG1494	fructose-1,6-bisphosphatase
AW20_RS15620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AW20_RS15640	COG2890	protein-(glutamine-N5) methyltransferase activity
AW20_RS15655	COG0009	L-threonylcarbamoyladenylate synthase
AW20_RS15670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AW20_RS15675	COG2259	Doxx family
AW20_RS15680	COG2190	(PTS) system
AW20_RS15690	COG0698	ribose 5-phosphate isomerase
AW20_RS15725	COG0356	it plays a direct role in the translocation of protons across the membrane
AW20_RS15775	COG3300	MHYT domain
AW20_RS15775	COG5001	Diguanylate cyclase
AW20_RS15790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW20_RS15795	COG0649	NAD binding
AW20_RS15810	COG0839	Belongs to the complex I subunit 6 family
AW20_RS15820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW20_RS15825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AW20_RS15830	COG1007	ATP synthesis coupled electron transport
AW20_RS15835	COG4836	Membrane
AW20_RS15850	COG2385	sporulation resulting in formation of a cellular spore
AW20_RS15855	COG4555	ABC transporter
AW20_RS15860	COG3279	Response regulator of the LytR AlgR family
AW20_RS15875	COG0739	heme binding
AW20_RS15890	COG1609	Transcriptional regulator
AW20_RS15935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AW20_RS15940	COG1682	transport, permease protein
AW20_RS15945	COG1134	teichoic acid transport
AW20_RS15950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW20_RS15965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AW20_RS15970	COG0745	RESPONSE REGULATOR receiver
AW20_RS15975	COG5002	protein histidine kinase activity
AW20_RS16010	COG1136	(ABC) transporter
AW20_RS16015	COG0577	efflux transmembrane transporter activity
AW20_RS16055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW20_RS16060	COG4715	Zinc finger, swim domain protein
AW20_RS16085	COG3584	3D domain protein
AW20_RS16085	COG1388	LysM domain
AW20_RS16090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AW20_RS16110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS16125	COG1368	sulfuric ester hydrolase activity
AW20_RS16135	COG2389	metal-binding protein
AW20_RS16145	COG1620	l-lactate permease
AW20_RS16155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW20_RS16160	COG1294	oxidase, subunit
AW20_RS16165	COG1271	oxidase subunit
AW20_RS16185	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AW20_RS16190	COG0583	DNA-binding transcription factor activity
AW20_RS16195	COG1511	domain protein
AW20_RS16200	COG0346	lactoylglutathione lyase activity
AW20_RS16210	COG1301	dicarboxylic acid transport
AW20_RS16215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW20_RS16225	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW20_RS16230	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW20_RS16235	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AW20_RS16245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AW20_RS16250	COG1447	Phosphotransferase system cellobiose-specific component IIA
AW20_RS16255	COG1486	melibiose metabolic process
AW20_RS16275	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AW20_RS16275	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AW20_RS16285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AW20_RS16290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AW20_RS16295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AW20_RS16300	COG1316	TRANSCRIPTIONal
AW20_RS16305	COG1739	Uncharacterized protein family UPF0029
AW20_RS16310	COG1307	EDD domain protein, DegV family
AW20_RS16320	COG1733	regulation of RNA biosynthetic process
AW20_RS16325	COG0791	NLP P60 protein
AW20_RS16325	COG1388	LysM domain
AW20_RS16330	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AW20_RS16335	COG1040	competence protein
AW20_RS16340	COG1278	Cold shock
AW20_RS16345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AW20_RS16350	COG0653	protein targeting
AW20_RS16370	COG2884	Cell division ATP-binding protein ftsE
AW20_RS16375	COG2177	Part of the ABC transporter FtsEX involved in
AW20_RS16380	COG0793	Belongs to the peptidase S41A family
AW20_RS16380	COG3409	Peptidoglycan-binding domain 1 protein
AW20_RS16385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW20_RS16390	COG1132	(ABC) transporter
AW20_RS16405	COG0655	NAD(P)H dehydrogenase (quinone) activity
AW20_RS16415	COG0583	DNA-binding transcription factor activity
AW20_RS16420	COG2855	membrane
AW20_RS16445	COG0789	Transcriptional regulator
AW20_RS16465	COG0556	nucleotide-excision repair
AW20_RS16470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AW20_RS16480	COG1950	PFAM Membrane protein of
AW20_RS16500	COG0110	maltose O-acetyltransferase activity
AW20_RS16505	COG0457	Tetratricopeptide repeat
AW20_RS16510	COG0492	ferredoxin-NADP+ reductase activity
AW20_RS16520	COG1051	belongs to the nudix hydrolase family
AW20_RS16530	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AW20_RS16540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW20_RS16545	COG0740	serine-type endopeptidase activity
AW20_RS16550	COG2323	membrane
AW20_RS16565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_RS16590	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AW20_RS16605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW20_RS16615	COG0149	triose-phosphate isomerase activity
AW20_RS16620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AW20_RS16630	COG4974	Belongs to the 'phage' integrase family
AW20_RS16655	COG4695	Portal protein
AW20_RS16755	COG1346	cytolysis
AW20_RS16760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AW20_RS16765	COG1647	Serine aminopeptidase, S33
AW20_RS16770	COG0557	exoribonuclease II activity
AW20_RS16820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS16835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW20_RS16840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AW20_RS16850	COG3290	protein histidine kinase activity
AW20_RS16850	COG0840	transmembrane signaling receptor activity
AW20_RS16860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW20_RS16865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AW20_RS16870	COG1252	NADH dehydrogenase
AW20_RS16880	COG1733	regulation of RNA biosynthetic process
AW20_RS16885	COG2814	Major facilitator Superfamily
AW20_RS16890	COG0656	L-ascorbic acid biosynthetic process
AW20_RS16905	COG2910	NAD(P)H-binding
AW20_RS16910	COG1115	amino acid carrier protein
AW20_RS16915	COG1115	amino acid carrier protein
AW20_RS16920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS16950	COG1611	Belongs to the LOG family
AW20_RS16965	COG0783	Belongs to the Dps family
AW20_RS16970	COG1115	amino acid carrier protein
AW20_RS16980	COG0490	domain, Protein
AW20_RS16985	COG0475	glutathione-regulated potassium exporter activity
AW20_RS17000	COG1741	Belongs to the pirin family
AW20_RS17005	COG3227	Zinc metalloprotease (Elastase)
AW20_RS17010	COG2151	metal-sulfur cluster biosynthetic enzyme
AW20_RS17035	COG5002	protein histidine kinase activity
AW20_RS17040	COG0745	RESPONSE REGULATOR receiver
AW20_RS17045	COG1376	ErfK ybiS ycfS ynhG family protein
AW20_RS17055	COG0586	Pfam SNARE associated Golgi protein
AW20_RS17090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS17100	COG0706	membrane insertase activity
AW20_RS17110	COG0531	amino acid
AW20_RS17115	COG2814	Major facilitator Superfamily
AW20_RS17135	COG0840	transmembrane signaling receptor activity
AW20_RS17140	COG0011	TIGRFAM Protein of
AW20_RS17155	COG1686	Belongs to the peptidase S11 family
AW20_RS17165	COG1024	Enoyl-CoA hydratase
AW20_RS17165	COG1250	3-hydroxyacyl-CoA dehydrogenase
AW20_RS17170	COG0183	Belongs to the thiolase family
AW20_RS17180	COG1960	acyl-CoA dehydrogenase activity
AW20_RS17185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS17190	COG1309	transcriptional regulator
AW20_RS17215	COG0039	L-malate dehydrogenase activity
AW20_RS17265	COG1393	Belongs to the ArsC family
AW20_RS17275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AW20_RS17280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_RS17295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AW20_RS17300	COG2011	ABC-type metal ion transport system permease component
AW20_RS17305	COG1464	Belongs to the NlpA lipoprotein family
AW20_RS17310	COG1464	Belongs to the NlpA lipoprotein family
AW20_RS17315	COG0396	ATPase activity
AW20_RS17320	COG0719	Fe-S assembly protein
AW20_RS17325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AW20_RS17330	COG0822	iron-sulfur transferase activity
AW20_RS17335	COG0719	Fe-S assembly protein
AW20_RS17350	COG1695	Transcriptional regulator
AW20_RS17360	COG0737	Belongs to the 5'-nucleotidase family
AW20_RS17365	COG3377	Domain of unknown function (DUF1805)
AW20_RS17375	COG0739	heme binding
AW20_RS17400	COG4377	Putative membrane peptidase family (DUF2324)
AW20_RS17405	COG0789	Transcriptional regulator
AW20_RS17415	COG4470	Protein conserved in bacteria
AW20_RS17435	COG1494	fructose-1,6-bisphosphatase
AW20_RS17440	COG2445	Protein of unknown function DUF86
AW20_RS17450	COG0647	UMP catabolic process
AW20_RS17455	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_RS17470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AW20_RS17475	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AW20_RS17485	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AW20_RS17490	COG4837	Protein of unknown function (DUF1462)
AW20_RS17530	COG2824	Alkylphosphonate utilization operon protein PhnA
AW20_RS17535	COG0390	transport system, permease component
AW20_RS17550	COG1252	NADH dehydrogenase
AW20_RS17565	COG0316	Belongs to the HesB IscA family
AW20_RS17585	COG1683	Conserved Protein
AW20_RS17600	COG3708	Transcriptional regulator
AW20_RS17615	COG1252	NADH dehydrogenase
AW20_RS17630	COG3584	3D domain protein
AW20_RS17645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AW20_RS17650	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AW20_RS17660	COG1268	BioY protein
AW20_RS17670	COG2050	protein possibly involved in aromatic compounds catabolism
AW20_RS17690	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW20_RS17695	COG5018	Exonuclease
AW20_RS17715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AW20_RS17725	COG2267	carboxylic ester hydrolase activity
AW20_RS17730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW20_RS17735	COG1522	sequence-specific DNA binding
AW20_RS17740	COG0436	Aminotransferase
AW20_RS17745	COG1098	S1 RNA binding domain
AW20_RS17750	COG2155	Conserved Protein
AW20_RS17760	COG0166	Belongs to the GPI family
AW20_RS17770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AW20_RS17775	COG1285	pathogenesis
AW20_RS17810	COG0544	peptidyl-prolyl cis-trans isomerase activity
AW20_RS17920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AW20_RS17925	COG0297	glycogen (starch) synthase activity
AW20_RS17930	COG0058	SHG alpha-glucan phosphorylase activity
AW20_RS17955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AW20_RS17960	COG1575	Belongs to the MenA family. Type 1 subfamily
AW20_RS17965	COG1169	isochorismate synthase
AW20_RS17970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AW20_RS17975	COG0596	Alpha beta hydrolase
AW20_RS17980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AW20_RS17990	COG4948	Mandelate Racemase Muconate Lactonizing
AW20_RS18020	COG3964	amidohydrolase
AW20_RS18040	COG2188	Transcriptional regulator
AW20_RS18060	COG1136	(ABC) transporter
AW20_RS18065	COG0577	efflux transmembrane transporter activity
AW20_RS18085	COG2205	protein histidine kinase activity
AW20_RS18090	COG0745	RESPONSE REGULATOR receiver
AW20_RS18095	COG3708	Transcriptional regulator
AW20_RS18095	COG2207	Transcriptional regulator
AW20_RS18100	COG1136	(ABC) transporter
AW20_RS18105	COG0577	efflux transmembrane transporter activity
AW20_RS18115	COG0586	Pfam SNARE associated Golgi protein
AW20_RS18150	COG1597	lipid kinase activity
AW20_RS18180	COG0745	RESPONSE REGULATOR receiver
AW20_RS18185	COG5002	protein histidine kinase activity
AW20_RS18220	COG1842	Phage shock protein A
AW20_RS18245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS18265	COG1294	oxidase, subunit
AW20_RS18270	COG1271	oxidase subunit
AW20_RS18275	COG0288	reversible hydration of carbon dioxide
AW20_RS18305	COG0494	nUDIX hydrolase
AW20_RS18330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_RS18335	COG1116	anion transmembrane transporter activity
AW20_RS18340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW20_RS18360	COG2267	carboxylic ester hydrolase activity
AW20_RS18365	COG4191	Histidine kinase
AW20_RS18370	COG5002	protein histidine kinase activity
AW20_RS18375	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW20_RS18430	COG0521	Mo-molybdopterin cofactor biosynthetic process
AW20_RS18440	COG0438	transferase activity, transferring glycosyl groups
AW20_RS18445	COG0671	phosphoesterase, PA-phosphatase related
AW20_RS18450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AW20_RS18455	COG2267	carboxylic ester hydrolase activity
AW20_RS18475	COG1794	racemase activity, acting on amino acids and derivatives
AW20_RS18485	COG1131	(ABC) transporter
AW20_RS18490	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AW20_RS18495	COG1242	4 iron, 4 sulfur cluster binding
AW20_RS18515	COG1136	(ABC) transporter
AW20_RS18525	COG0582	viral genome integration into host DNA
AW20_RS18530	COG0490	domain, Protein
AW20_RS18535	COG0475	glutathione-regulated potassium exporter activity
AW20_RS18540	COG2814	Major facilitator Superfamily
AW20_RS18585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AW20_RS18595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_RS18620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_RS18630	COG0303	'Molybdopterin
AW20_RS18635	COG1763	Mo-molybdopterin cofactor biosynthetic process
AW20_RS18640	COG0314	molybdopterin synthase activity
AW20_RS18655	COG4975	Glucose uptake
AW20_RS18665	COG1329	Transcriptional regulator
AW20_RS18685	COG3832	glyoxalase III activity
AW20_RS18695	COG2814	Major facilitator Superfamily
AW20_RS18700	COG2081	HI0933 family
AW20_RS18705	COG2244	polysaccharide biosynthetic process
AW20_RS18710	COG1187	pseudouridine synthase activity
AW20_RS18715	COG1349	DNA-binding transcription factor activity
AW20_RS18740	COG1523	belongs to the glycosyl hydrolase 13 family
AW20_RS18745	COG0510	thiamine kinase activity
AW20_RS18760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS18770	COG1363	Peptidase, m42
AW20_RS18775	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AW20_RS18780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_RS18785	COG4848	Belongs to the UPF0354 family
AW20_RS18790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AW20_RS18800	COG1674	ftsk spoiiie
AW20_RS18815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS18835	COG2309	aminopeptidase activity
AW20_RS18845	COG3118	belongs to the thioredoxin family
AW20_RS18850	COG4851	CamS sex pheromone cAM373 precursor
AW20_RS18860	COG1609	Transcriptional regulator
AW20_RS18895	COG0666	response to abiotic stimulus
AW20_RS18905	COG0745	RESPONSE REGULATOR receiver
AW20_RS18915	COG0123	including yeast histone deacetylase and acetoin utilization protein
AW20_RS18920	COG0517	IMP dehydrogenase activity
AW20_RS18925	COG0454	-acetyltransferase
AW20_RS18930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW20_RS18940	COG1595	DNA-templated transcription, initiation
AW20_RS18970	COG0626	cystathionine gamma-synthase activity
AW20_RS18975	COG1956	GAF domain-containing protein
AW20_RS18985	COG0697	spore germination
AW20_RS18990	COG0583	DNA-binding transcription factor activity
AW20_RS19000	COG1104	cysteine desulfurase activity
AW20_RS19015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AW20_RS19025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AW20_RS19040	COG3874	Sporulation protein YtfJ
AW20_RS19045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AW20_RS19050	COG0827	DNA restriction-modification system
AW20_RS19055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AW20_RS19075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS19115	COG0589	response to stress
AW20_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS19135	COG1476	TRANSCRIPTIONal
AW20_RS19145	COG0662	Cupin 2, conserved barrel domain protein
AW20_RS19150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS19185	COG0006	proline dipeptidase activity
AW20_RS19200	COG4109	DRTGG domain
AW20_RS19220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AW20_RS19235	COG0587	DNA-directed DNA polymerase activity
AW20_RS19240	COG0281	malic enzyme
AW20_RS19245	COG1725	Transcriptional regulator
AW20_RS19270	COG3030	protein affecting phage T7 exclusion by the F plasmid
AW20_RS19275	COG0628	permease
AW20_RS19290	COG0372	Belongs to the citrate synthase family
AW20_RS19295	COG0538	isocitrate dehydrogenase activity
AW20_RS19315	COG0745	RESPONSE REGULATOR receiver
AW20_RS19320	COG5002	protein histidine kinase activity
AW20_RS19325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW20_RS19325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AW20_RS19335	COG1971	Probably functions as a manganese efflux pump
AW20_RS19340	COG0237	dephospho-CoA kinase activity
AW20_RS19345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AW20_RS19350	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AW20_RS19360	COG3611	Membrane attachment protein
AW20_RS19365	COG1484	DNA-dependent DNA replication
AW20_RS19375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AW20_RS19400	COG1363	Peptidase, m42
AW20_RS19405	COG1309	transcriptional regulator
AW20_RS19410	COG1566	PFAM secretion protein HlyD family protein
AW20_RS19415	COG2814	Major facilitator Superfamily
AW20_RS19440	COG1418	mRNA catabolic process
AW20_RS19450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AW20_RS19495	COG1286	toxin biosynthetic process
AW20_RS19515	COG1187	pseudouridine synthase activity
AW20_RS19520	COG1114	Component of the transport system for branched-chain amino acids
AW20_RS19525	COG5386	Cell surface protein
AW20_RS19535	COG5386	Cell surface protein
AW20_RS19550	COG1120	ATPase activity
AW20_RS19555	COG4509	Sortase family
AW20_RS19570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AW20_RS19575	COG4895	conserved protein (DUF2196)
AW20_RS19585	COG0745	RESPONSE REGULATOR receiver
AW20_RS19590	COG2205	protein histidine kinase activity
AW20_RS19595	COG1131	(ABC) transporter
AW20_RS19625	COG2318	DinB family
AW20_RS19645	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS19650	COG1309	transcriptional regulator
AW20_RS19655	COG1024	Enoyl-CoA hydratase
AW20_RS19660	COG2086	electron transfer activity
AW20_RS19665	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AW20_RS19670	COG3118	belongs to the thioredoxin family
AW20_RS19680	COG1719	4-vinyl reductase, 4VR
AW20_RS19685	COG2009	succinate dehydrogenase
AW20_RS19690	COG1053	succinate dehydrogenase
AW20_RS19695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AW20_RS19700	COG0824	Thioesterase
AW20_RS19705	COG1876	peptidase activity
AW20_RS19710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AW20_RS19720	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AW20_RS19730	COG1668	transmembrane transport
AW20_RS19735	COG1959	2 iron, 2 sulfur cluster binding
AW20_RS19745	COG0697	spore germination
AW20_RS19750	COG1396	sequence-specific DNA binding
AW20_RS19755	COG1983	PspC domain protein
AW20_RS19770	COG3279	Response regulator of the LytR AlgR family
AW20_RS19780	COG4608	Belongs to the ABC transporter superfamily
AW20_RS19785	COG0444	Belongs to the ABC transporter superfamily
AW20_RS19805	COG0402	S-adenosylhomocysteine deaminase activity
AW20_RS19810	COG0402	S-adenosylhomocysteine deaminase activity
AW20_RS19820	COG2233	PERMEase
AW20_RS19825	COG2197	response regulator
AW20_RS19840	COG1309	transcriptional regulator
AW20_RS19860	COG5401	PFAM Sporulation and spore germination
AW20_RS19875	COG0622	Phosphoesterase
AW20_RS19925	COG1067	ATP-dependent peptidase activity
AW20_RS19925	COG0470	DNA polymerase III
AW20_RS19940	COG1764	response to oxidative stress
AW20_RS19945	COG1846	Transcriptional regulator
AW20_RS19955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AW20_RS19965	COG1587	Uroporphyrinogen-III synthase
AW20_RS19970	COG0113	porphobilinogen synthase activity
AW20_RS19980	COG1388	LysM domain
AW20_RS19990	COG0525	valine-tRNA ligase activity
AW20_RS19995	COG0285	dihydrofolate synthase activity
AW20_RS20015	COG1077	Cell shape determining protein MreB Mrl
AW20_RS20035	COG2894	cell division
AW20_RS20040	COG0739	heme binding
AW20_RS20045	COG1994	Peptidase M50
AW20_RS20050	COG1530	ribonuclease E activity
AW20_RS20060	COG2868	ribosomal protein
AW20_RS20070	COG3290	protein histidine kinase activity
AW20_RS20075	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AW20_RS20080	COG0745	RESPONSE REGULATOR receiver
AW20_RS20095	COG1136	(ABC) transporter
AW20_RS20100	COG0577	efflux transmembrane transporter activity
AW20_RS20105	COG0577	efflux transmembrane transporter activity
AW20_RS20110	COG0077	Prephenate dehydratase
AW20_RS20115	COG2258	MOSC domain
AW20_RS20120	COG1827	regulation of RNA biosynthetic process
AW20_RS20125	COG1104	cysteine desulfurase activity
AW20_RS20130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AW20_RS20135	COG0157	Belongs to the NadC ModD family
AW20_RS20160	COG0640	Transcriptional regulator
AW20_RS20165	COG0697	spore germination
AW20_RS20170	COG0697	spore germination
AW20_RS20180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AW20_RS20210	COG1862	Preprotein translocase
AW20_RS20220	COG2323	membrane
AW20_RS20225	COG2244	polysaccharide biosynthetic process
AW20_RS20235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW20_RS20235	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AW20_RS20240	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AW20_RS20245	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AW20_RS20245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AW20_RS20255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AW20_RS20280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AW20_RS20295	COG1959	2 iron, 2 sulfur cluster binding
AW20_RS20300	COG1104	cysteine desulfurase activity
AW20_RS20305	COG0482	sulfurtransferase activity
AW20_RS20315	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AW20_RS20335	COG0628	permease
AW20_RS20345	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW20_RS20365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AW20_RS20370	COG4122	O-methyltransferase activity
AW20_RS20395	COG0768	penicillin binding
AW20_RS20420	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AW20_RS20425	COG0626	cystathionine gamma-synthase activity
AW20_RS20430	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS20430	COG1454	alcohol dehydrogenase
AW20_RS20440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS20480	COG2259	Doxx family
AW20_RS20500	COG3186	Phenylalanine-4-hydroxylase
AW20_RS20505	COG1404	Belongs to the peptidase S8 family
AW20_RS20540	COG2267	carboxylic ester hydrolase activity
AW20_RS20550	COG1785	Belongs to the alkaline phosphatase family
AW20_RS20560	COG2357	RelA SpoT domain protein
AW20_RS20565	COG0778	Nitroreductase
AW20_RS20575	COG1595	DNA-templated transcription, initiation
AW20_RS20600	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AW20_RS20605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AW20_RS20615	COG1534	Rna-binding protein
AW20_RS20625	COG1713	HD superfamily hydrolase involved in NAD metabolism
AW20_RS20630	COG0799	negative regulation of ribosome biogenesis
AW20_RS20635	COG2226	methyltransferase
AW20_RS20640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_RS20645	COG1596	polysaccharide export
AW20_RS20645	COG1555	photosystem II stabilization
AW20_RS20650	COG2131	deaminase
AW20_RS20655	COG2333	competence protein COMEC
AW20_RS20655	COG0658	competence protein
AW20_RS20665	COG1466	dna polymerase III delta subunit
AW20_RS20690	COG1733	regulation of RNA biosynthetic process
AW20_RS20695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AW20_RS20725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AW20_RS20730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW20_RS20735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AW20_RS20740	COG1610	YqeY-like protein
AW20_RS20760	COG1702	phosphate starvation-inducible protein PhoH
AW20_RS20765	COG1480	7TM receptor with intracellular HD hydrolase
AW20_RS20775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AW20_RS20780	COG0295	cytidine deaminase activity
AW20_RS20785	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AW20_RS20800	COG0517	IMP dehydrogenase activity
AW20_RS20820	COG0358	DNA primase activity
AW20_RS20830	COG2010	Cytochrome c
AW20_RS20835	COG2384	SAM-dependent methyltransferase
AW20_RS20840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AW20_RS20870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS20875	COG1121	(ABC) transporter
AW20_RS20880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW20_RS20885	COG0735	belongs to the Fur family
AW20_RS20910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AW20_RS20915	COG0477	Major facilitator Superfamily
AW20_RS20925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AW20_RS20930	COG0573	inorganic phosphate transmembrane transporter activity
AW20_RS20935	COG0581	inorganic phosphate transmembrane transporter activity
AW20_RS20945	COG0704	Plays a role in the regulation of phosphate uptake
AW20_RS20950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AW20_RS20955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AW20_RS20960	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AW20_RS20965	COG4483	Protein conserved in bacteria
AW20_RS20970	COG1940	carbohydrate kinase activity
AW20_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS21005	COG0626	cystathionine gamma-synthase activity
AW20_RS21010	COG0626	cystathionine gamma-synthase activity
AW20_RS21020	COG0646	methionine synthase
AW20_RS21020	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AW20_RS21025	COG1410	methionine synthase
AW20_RS21025	COG0646	methionine synthase
AW20_RS21030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AW20_RS21080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AW20_RS21085	COG1459	type II secretion system
AW20_RS21095	COG4970	Tfp pilus assembly protein FimT
AW20_RS21150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AW20_RS21180	COG1725	Transcriptional regulator
AW20_RS21185	COG1131	(ABC) transporter
AW20_RS21225	COG2076	Multidrug Resistance protein
AW20_RS21230	COG2076	Multidrug Resistance protein
AW20_RS21240	COG1609	Transcriptional regulator
AW20_RS21245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AW20_RS21250	COG0095	Lipoate-protein ligase
AW20_RS21270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AW20_RS21280	COG3872	metal-dependent enzyme
AW20_RS21295	COG0006	proline dipeptidase activity
AW20_RS21320	COG3854	ATPases associated with a variety of cellular activities
AW20_RS21365	COG0511	ligase activity, forming carbon-carbon bonds
AW20_RS21370	COG0439	Biotin carboxylase
AW20_RS21375	COG1302	Protein conserved in bacteria
AW20_RS21400	COG0142	geranyltranstransferase activity
AW20_RS21410	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AW20_RS21420	COG0497	DNA recombination
AW20_RS21425	COG0750	zinc metalloprotease
AW20_RS21430	COG0745	RESPONSE REGULATOR receiver
AW20_RS21440	COG3093	addiction module antidote protein HigA
AW20_RS21445	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_RS21455	COG3829	transcription factor binding
AW20_RS21455	COG3290	protein histidine kinase activity
AW20_RS21465	COG0280	phosphate acetyltransferase
AW20_RS21480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AW20_RS21485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW20_RS21490	COG0022	dehydrogenase e1 component
AW20_RS21495	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_RS21505	COG0772	Belongs to the SEDS family
AW20_RS21530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AW20_RS21535	COG0765	amino acid transport
AW20_RS21540	COG1126	abc transporter atp-binding protein
AW20_RS21545	COG4129	membrane
AW20_RS21550	COG1376	ErfK ybiS ycfS ynhG family protein
AW20_RS21565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS21570	COG2195	Cleaves the N-terminal amino acid of tripeptides
AW20_RS21580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW20_RS21600	COG1760	l-serine dehydratase
AW20_RS21605	COG1760	l-serine dehydratase
AW20_RS21625	COG0300	oxidoreductase activity
AW20_RS21640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AW20_RS21650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW20_RS21670	COG1522	sequence-specific DNA binding
AW20_RS21680	COG0737	Belongs to the 5'-nucleotidase family
AW20_RS21695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AW20_RS21710	COG1073	alpha beta
AW20_RS21710	COG2226	methyltransferase
AW20_RS21715	COG4106	trans-aconitate 2-methyltransferase activity
AW20_RS21740	COG0307	riboflavin synthase, alpha
AW20_RS21745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW20_RS21745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AW20_RS21760	COG1073	alpha beta
AW20_RS21765	COG0456	acetyltransferase
AW20_RS21770	COG1609	Transcriptional regulator
AW20_RS21775	COG2056	Na+-H+ antiporter family
AW20_RS21780	COG0596	Alpha beta hydrolase
AW20_RS21790	COG0737	Belongs to the 5'-nucleotidase family
AW20_RS21790	COG4085	toxin activity
AW20_RS21790	COG1525	nuclease
AW20_RS21800	COG0456	acetyltransferase
AW20_RS21800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW20_RS21805	COG0656	L-ascorbic acid biosynthetic process
AW20_RS21810	COG0667	Aldo Keto reductase
AW20_RS21830	COG1300	Membrane
AW20_RS21835	COG0735	belongs to the Fur family
AW20_RS21845	COG4974	Belongs to the 'phage' integrase family
AW20_RS21870	COG0598	Magnesium transport protein CorA
AW20_RS21885	COG1846	Transcriptional regulator
AW20_RS21905	COG1131	(ABC) transporter
AW20_RS21910	COG1725	Transcriptional regulator
AW20_RS21915	COG1686	Belongs to the peptidase S11 family
AW20_RS21935	COG0733	neurotransmitter:sodium symporter activity
AW20_RS21960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_RS21975	COG0697	spore germination
AW20_RS21980	COG0561	phosphatase activity
AW20_RS21985	COG4086	secreted protein
AW20_RS21990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AW20_RS22000	COG0456	acetyltransferase
AW20_RS22005	COG1547	Domain of unknown function (DUF309)
AW20_RS22035	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AW20_RS22045	COG2188	Transcriptional regulator
AW20_RS22055	COG3711	transcriptional antiterminator
AW20_RS22060	COG2190	(PTS) system
AW20_RS22060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AW20_RS22060	COG1263	PTS System
AW20_RS22085	COG0778	Nitroreductase
AW20_RS22090	COG3706	GGDEF domain
AW20_RS22110	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AW20_RS22130	COG0436	Aminotransferase
AW20_RS22135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AW20_RS22145	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AW20_RS22155	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS22160	COG1695	Transcriptional regulator
AW20_RS22200	COG0183	Belongs to the thiolase family
AW20_RS22240	COG3842	ATPase activity
AW20_RS22245	COG0366	Alpha amylase catalytic
AW20_RS22255	COG2182	Extracellular solute-binding protein
AW20_RS22260	COG1175	transmembrane transport
AW20_RS22265	COG3833	ABC-type maltose transport systems, permease component
AW20_RS22270	COG1609	Transcriptional regulator
AW20_RS22275	COG0436	Aminotransferase
AW20_RS22285	COG2205	protein histidine kinase activity
AW20_RS22295	COG3209	COG3209 Rhs family protein
AW20_RS22320	COG2814	Major facilitator Superfamily
AW20_RS22360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AW20_RS22370	COG1408	metallophosphoesterase
AW20_RS22375	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS22380	COG2200	EAL domain
AW20_RS22395	COG4703	Protein of unknown function (DUF1797)
AW20_RS22405	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AW20_RS22415	COG0517	IMP dehydrogenase activity
AW20_RS22420	COG0583	DNA-binding transcription factor activity
AW20_RS22440	COG0569	domain protein
AW20_RS22445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW20_RS22455	COG0561	phosphatase activity
AW20_RS22460	COG0242	peptide deformylase activity
AW20_RS22470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AW20_RS22475	COG0022	dehydrogenase e1 component
AW20_RS22480	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_RS22525	COG1982	Orn Lys Arg decarboxylase major
AW20_RS22545	COG0483	inositol monophosphate 1-phosphatase activity
AW20_RS22570	COG4896	Protein conserved in bacteria
AW20_RS22580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AW20_RS22585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AW20_RS22595	COG0772	Belongs to the SEDS family
AW20_RS22600	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AW20_RS22635	COG3336	cytochrome c oxidase
AW20_RS22650	COG2340	Cysteine-rich secretory protein family
AW20_RS22665	COG0406	alpha-ribazole phosphatase activity
AW20_RS22670	COG3679	Belongs to the UPF0342 family
AW20_RS22685	COG0742	ribosomal rna small subunit methyltransferase
AW20_RS22695	COG3314	Sporulation integral membrane protein YlbJ
AW20_RS22700	COG1752	Esterase of the alpha-beta hydrolase superfamily
AW20_RS22705	COG3480	Lon protease (S16) C-terminal proteolytic domain
AW20_RS22715	COG0582	viral genome integration into host DNA
AW20_RS22730	COG1396	sequence-specific DNA binding
AW20_RS22740	COG1396	sequence-specific DNA binding
AW20_RS22770	COG1484	DNA-dependent DNA replication
AW20_RS22795	COG1191	sigma factor activity
AW20_RS22805	COG0756	dUTP diphosphatase activity
AW20_RS22875	COG0582	viral genome integration into host DNA
AW20_RS22900	COG4626	Terminase
AW20_RS22900	COG1802	Transcriptional regulator
AW20_RS22995	COG4824	toxin secretion phage lysis holin
AW20_RS23045	COG1399	metal-binding, possibly nucleic acid-binding protein
AW20_RS23050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AW20_RS23065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AW20_RS23080	COG4839	cell division protein FtsL
AW20_RS23090	COG0768	penicillin binding
AW20_RS23095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AW20_RS23110	COG0772	Belongs to the SEDS family
AW20_RS23120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AW20_RS23125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AW20_RS23130	COG0849	cell division
AW20_RS23135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AW20_RS23145	COG1191	sigma factor activity
AW20_RS23150	COG1191	sigma factor activity
AW20_RS23155	COG1873	PFAM PRC-barrel domain
AW20_RS23165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AW20_RS23175	COG0762	integral membrane protein
AW20_RS23180	COG2302	S4 RNA-binding domain
AW20_RS23185	COG3599	regulation of cell shape
AW20_RS23205	COG0564	pseudouridine synthase activity
AW20_RS23270	COG3069	C4-dicarboxylate transmembrane transporter activity
AW20_RS23285	COG0006	proline dipeptidase activity
AW20_RS23295	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AW20_RS23300	COG1561	YicC-like family, N-terminal region
AW20_RS23320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW20_RS23325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AW20_RS23330	COG0242	peptide deformylase activity
AW20_RS23340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AW20_RS23340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AW20_RS23350	COG0631	protein serine/threonine phosphatase activity
AW20_RS23355	COG2815	serine threonine protein kinase
AW20_RS23355	COG0515	serine threonine protein kinase
AW20_RS23360	COG1162	GTPase activity
AW20_RS23365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AW20_RS23370	COG1564	THIamine pyrophosphokinase
AW20_RS23385	COG1302	Protein conserved in bacteria
AW20_RS23390	COG1461	Dihydroxyacetone kinase
AW20_RS23395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AW20_RS23410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AW20_RS23415	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS23420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AW20_RS23430	COG1196	nuclear chromosome segregation
AW20_RS23435	COG0552	protein localization to endoplasmic reticulum
AW20_RS23445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AW20_RS23455	COG1837	Belongs to the UPF0109 family
AW20_RS23495	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AW20_RS23505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AW20_RS23515	COG4974	Belongs to the 'phage' integrase family
AW20_RS23545	COG0528	UMP kinase activity
AW20_RS23555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AW20_RS23560	COG4589	Belongs to the CDS family
AW20_RS23570	COG0750	zinc metalloprotease
AW20_RS23590	COG0195	Participates in both transcription termination and antitermination
AW20_RS23595	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AW20_RS23600	COG1358	cellular component organization or biogenesis
AW20_RS23610	COG1550	Protein conserved in bacteria
AW20_RS23620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AW20_RS23625	COG0196	riboflavin kinase activity
AW20_RS23640	COG0726	polysaccharide deacetylase
AW20_RS23645	COG0612	Peptidase, M16
AW20_RS23650	COG1873	PFAM PRC-barrel domain
AW20_RS23655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AW20_RS23660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AW20_RS23665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AW20_RS23670	COG0527	aspartate kinase activity
AW20_RS23685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AW20_RS23690	COG0740	serine-type endopeptidase activity
AW20_RS23700	COG1674	ftsk spoiiie
AW20_RS23705	COG2188	Transcriptional regulator
AW20_RS23735	COG0612	Peptidase, M16
AW20_RS23740	COG0612	Peptidase, M16
AW20_RS23745	COG0300	oxidoreductase activity
AW20_RS23760	COG1426	Protein conserved in bacteria
AW20_RS23765	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AW20_RS23790	COG1692	metallophosphoesterase
AW20_RS23795	COG2359	stage V sporulation protein S
AW20_RS23805	COG0674	pyruvate-flavodoxin oxidoreductase activity
AW20_RS23805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AW20_RS23810	COG1013	pyruvate-flavodoxin oxidoreductase activity
AW20_RS23815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AW20_RS23820	COG4550	Control of competence regulator ComK, YlbF/YmcA
AW20_RS23840	COG1131	(ABC) transporter
AW20_RS23865	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AW20_RS23875	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AW20_RS23880	COG1368	sulfuric ester hydrolase activity
AW20_RS23885	COG0562	UDP-galactopyranose mutase
AW20_RS23890	COG3773	Cell wall hydrolase
AW20_RS23895	COG1404	Belongs to the peptidase S8 family
AW20_RS23910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW20_RS23915	COG0508	dehydrogenase complex catalyzes the overall conversion of
AW20_RS23915	COG0596	Alpha beta hydrolase
AW20_RS23920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS23925	COG1380	Effector of murein hydrolase LrgA
AW20_RS23930	COG1346	cytolysis
AW20_RS23950	COG3300	MHYT domain
AW20_RS23950	COG5001	Diguanylate cyclase
AW20_RS23955	COG0346	lactoylglutathione lyase activity
AW20_RS23960	COG2267	carboxylic ester hydrolase activity
AW20_RS23975	COG2364	Membrane
AW20_RS23985	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AW20_RS23990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AW20_RS23995	COG2169	Transcriptional regulator
AW20_RS24000	COG0708	Exodeoxyribonuclease III
AW20_RS24015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS24020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS24025	COG1120	ATPase activity
AW20_RS24030	COG2819	hydrolase of the alpha beta superfamily
AW20_RS24040	COG1937	Protein conserved in bacteria
AW20_RS24045	COG2608	mercury ion transmembrane transporter activity
AW20_RS24050	COG2217	Heavy metal translocating P-type atpase
AW20_RS24060	COG2116	formate transmembrane transporter activity
AW20_RS24065	COG1408	metallophosphoesterase
AW20_RS24075	COG1113	amino acid transport
AW20_RS24090	COG2322	membrane
AW20_RS24100	COG1349	DNA-binding transcription factor activity
AW20_RS24105	COG1105	Belongs to the carbohydrate kinase PfkB family
AW20_RS24110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AW20_RS24110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW20_RS24110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AW20_RS24115	COG3584	3D domain protein
AW20_RS24115	COG1388	LysM domain
AW20_RS24145	COG0464	growth
AW20_RS24150	COG2860	membrane
AW20_RS24160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AW20_RS24165	COG0789	Transcriptional regulator
AW20_RS24170	COG0174	glutamine synthetase
AW20_RS24195	COG1396	sequence-specific DNA binding
AW20_RS24275	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AW20_RS24320	COG1595	DNA-templated transcription, initiation
AW20_RS24480	COG4824	toxin secretion phage lysis holin
AW20_RS24485	COG3409	Peptidoglycan-binding domain 1 protein
AW20_RS24485	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_RS24485	COG1388	LysM domain
AW20_RS24520	COG1695	Transcriptional regulator
AW20_RS24540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AW20_RS24565	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AW20_RS24570	COG3639	organic phosphonate transmembrane transporter activity
AW20_RS24605	COG1132	(ABC) transporter
AW20_RS24610	COG1132	(ABC) transporter
AW20_RS24625	COG5632	N-Acetylmuramoyl-L-alanine amidase
AW20_RS24625	COG3409	Peptidoglycan-binding domain 1 protein
AW20_RS24650	COG1346	cytolysis
AW20_RS24655	COG1380	Effector of murein hydrolase LrgA
AW20_RS24660	COG0583	DNA-binding transcription factor activity
AW20_RS24670	COG0785	Cytochrome C biogenesis protein
AW20_RS24675	COG4846	Membrane protein involved in cytochrome C biogenesis
AW20_RS24730	COG2226	methyltransferase
AW20_RS24755	COG0010	Belongs to the arginase family
AW20_RS24760	COG1329	Transcriptional regulator
AW20_RS24765	COG1902	pentaerythritol trinitrate reductase activity
AW20_RS24770	COG0069	glutamate synthase activity
AW20_RS24775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AW20_RS24780	COG0346	lactoylglutathione lyase activity
AW20_RS24785	COG0400	carboxylic ester hydrolase activity
AW20_RS24790	COG5002	protein histidine kinase activity
AW20_RS24800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS24845	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS24850	COG1268	BioY protein
AW20_RS24855	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS24860	COG0183	Belongs to the thiolase family
AW20_RS24875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AW20_RS24915	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AW20_RS24920	COG2274	protein secretion by the type I secretion system
AW20_RS24930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AW20_RS24960	COG0824	Thioesterase
AW20_RS24965	COG4841	protein insertion into membrane
AW20_RS24970	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW20_RS24985	COG0745	RESPONSE REGULATOR receiver
AW20_RS24990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AW20_RS24995	COG1832	CoA-binding protein
AW20_RS25005	COG0187	DNA topoisomerase II activity
AW20_RS25010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AW20_RS25015	COG0673	inositol 2-dehydrogenase activity
AW20_RS25025	COG1131	(ABC) transporter
AW20_RS25050	COG1595	DNA-templated transcription, initiation
AW20_RS25060	COG1316	TRANSCRIPTIONal
AW20_RS25065	COG1301	dicarboxylic acid transport
AW20_RS25070	COG4166	transmembrane transport
AW20_RS25075	COG4166	transmembrane transport
AW20_RS25080	COG4166	transmembrane transport
AW20_RS25085	COG2226	methyltransferase
AW20_RS25125	COG0697	spore germination
AW20_RS25135	COG3383	formate dehydrogenase (NAD+) activity
AW20_RS25140	COG2427	Protein of unknown function (DUF1641)
AW20_RS25145	COG5609	conserved protein (DUF2294)
AW20_RS25150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AW20_RS25160	COG2116	formate transmembrane transporter activity
AW20_RS25165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AW20_RS25170	COG0303	'Molybdopterin
AW20_RS25175	COG0314	molybdopterin synthase activity
AW20_RS25185	COG0489	protein tyrosine kinase activity
AW20_RS25200	COG3326	Membrane
AW20_RS25205	COG2962	Rard protein
AW20_RS25210	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AW20_RS25215	COG1657	PFAM Prenyltransferase squalene oxidase
AW20_RS25225	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS25230	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS25240	COG4145	pantothenate transmembrane transporter activity
AW20_RS25255	COG0165	Argininosuccinate lyase
AW20_RS25265	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS25295	COG0716	FMN binding
AW20_RS25335	COG2720	vancomycin resistance protein
AW20_RS25340	COG2514	catechol 2,3-dioxygenase activity
AW20_RS25350	COG1285	pathogenesis
AW20_RS25360	COG1024	Enoyl-CoA hydratase
AW20_RS25365	COG1216	Glycosyl transferase, family 2
AW20_RS25395	COG0277	FAD linked oxidase domain protein
AW20_RS25400	COG0385	Bile acid
AW20_RS25410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AW20_RS25415	COG2808	Putative FMN-binding domain
AW20_RS25435	COG0604	alcohol dehydrogenase
AW20_RS25440	COG0640	Transcriptional regulator
AW20_RS25465	COG0584	glycerophosphoryl diester phosphodiesterase
AW20_RS25495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AW20_RS25500	COG1164	Oligoendopeptidase f
AW20_RS25520	COG1193	negative regulation of DNA recombination
AW20_RS25540	COG0583	DNA-binding transcription factor activity
AW20_RS25570	COG0384	phenazine biosynthesis protein PhzF
AW20_RS25575	COG3739	integral membrane protein
AW20_RS25580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS25585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AW20_RS25595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS25615	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AW20_RS25620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AW20_RS25655	COG2814	Major facilitator Superfamily
AW20_RS25660	COG1113	amino acid transport
AW20_RS25700	COG2072	flavoprotein involved in K transport
AW20_RS25735	COG3757	hydrolase, family 25
AW20_RS25735	COG3409	Peptidoglycan-binding domain 1 protein
AW20_RS25740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS25750	COG1151	hydroxylamine reductase activity
AW20_RS25775	COG3152	Membrane
AW20_RS25795	COG1309	transcriptional regulator
AW20_RS25810	COG1191	sigma factor activity
AW20_RS25845	COG1733	regulation of RNA biosynthetic process
AW20_RS25855	COG0318	PFAM AMP-dependent synthetase and ligase
AW20_RS25865	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS25875	COG0384	phenazine biosynthesis protein PhzF
AW20_RS25895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS25910	COG1733	regulation of RNA biosynthetic process
AW20_RS25915	COG1733	regulation of RNA biosynthetic process
AW20_RS25920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AW20_RS25930	COG2188	Transcriptional regulator
AW20_RS25935	COG1733	regulation of RNA biosynthetic process
AW20_RS25945	COG1393	Belongs to the ArsC family
AW20_RS25970	COG0814	amino acid
AW20_RS25975	COG0346	lactoylglutathione lyase activity
AW20_RS25990	COG2814	Major facilitator Superfamily
AW20_RS25995	COG0656	L-ascorbic acid biosynthetic process
AW20_RS26020	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS26040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW20_RS26045	COG0604	alcohol dehydrogenase
AW20_RS26050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW20_RS26055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AW20_RS26065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AW20_RS26070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AW20_RS26080	COG1070	Carbohydrate kinase
AW20_RS26085	COG2706	6-phosphogluconolactonase activity
AW20_RS26090	COG3813	Protein conserved in bacteria
AW20_RS26095	COG1357	PFAM Pentapeptide repeats (8 copies)
AW20_RS26100	COG0697	spore germination
AW20_RS26105	COG0789	Transcriptional regulator
AW20_RS26110	COG1253	flavin adenine dinucleotide binding
AW20_RS26140	COG0477	Major facilitator Superfamily
AW20_RS26150	COG2226	methyltransferase
AW20_RS26170	COG0628	permease
AW20_RS26175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AW20_RS26185	COG1136	(ABC) transporter
AW20_RS26185	COG0577	efflux transmembrane transporter activity
AW20_RS26200	COG0110	maltose O-acetyltransferase activity
AW20_RS26205	COG0738	Major facilitator superfamily
AW20_RS26210	COG1940	carbohydrate kinase activity
AW20_RS26215	COG0346	lactoylglutathione lyase activity
AW20_RS26250	COG1011	Hydrolase
AW20_RS26275	COG1131	(ABC) transporter
AW20_RS26285	COG1028	Short-chain dehydrogenase reductase Sdr
AW20_RS26305	COG0778	Nitroreductase
AW20_RS26310	COG1733	regulation of RNA biosynthetic process
AW20_RS26325	COG0124	histidyl-tRNA synthetase
AW20_RS26330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AW20_RS26335	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AW20_RS26340	COG3620	sequence-specific DNA binding
AW20_RS26355	COG2356	endonuclease I
AW20_RS26360	COG1288	antiporter activity
AW20_RS26365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AW20_RS26380	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AW20_RS26385	COG1122	ATPase activity
AW20_RS26415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AW20_RS26425	COG2031	fatty acid transporter
AW20_RS26440	COG1309	transcriptional regulator
AW20_RS26445	COG2076	Multidrug Resistance protein
AW20_RS26465	COG1131	(ABC) transporter
AW20_RS26470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AW20_RS26485	COG2814	Major facilitator Superfamily
AW20_RS26490	COG1846	Transcriptional regulator
AW20_RS26500	COG0477	Major facilitator Superfamily
AW20_RS26555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AW20_RS26555	COG2207	Transcriptional regulator
AW20_RS26565	COG0662	Cupin 2, conserved barrel domain protein
AW20_RS26580	COG1595	DNA-templated transcription, initiation
AW20_RS26600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AW20_RS26615	COG0531	amino acid
AW20_RS26620	COG1522	sequence-specific DNA binding
AW20_RS26625	COG1335	isochorismatase
AW20_RS26635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AW20_RS26640	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AW20_RS26650	COG1760	l-serine dehydratase
AW20_RS26655	COG1760	l-serine dehydratase
AW20_RS26660	COG0814	amino acid
AW20_RS26675	COG1309	transcriptional regulator
AW20_RS26680	COG2814	Major facilitator Superfamily
AW20_RS26695	COG0534	Mate efflux family protein
AW20_RS26725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AW20_RS26745	COG0457	Tetratricopeptide repeat
AW20_RS26750	COG1609	Transcriptional regulator
AW20_RS26760	COG0561	phosphatase activity
AW20_RS26765	COG0673	inositol 2-dehydrogenase activity
AW20_RS26770	COG0738	Major facilitator superfamily
AW20_RS26795	COG1619	proteins homologs of microcin C7 resistance protein MccF
AW20_RS26805	COG0583	DNA-binding transcription factor activity
AW20_RS26815	COG1139	Iron-sulfur cluster binding protein
AW20_RS26820	COG1556	Lactate utilization protein
AW20_RS26825	COG2271	Major facilitator Superfamily
AW20_RS26830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AW20_RS26835	COG2808	Putative FMN-binding domain
AW20_RS26845	COG1846	Transcriptional regulator
AW20_RS26850	COG2364	Membrane
AW20_RS26860	COG3850	Histidine kinase
AW20_RS26860	COG5002	protein histidine kinase activity
AW20_RS26880	COG0577	efflux transmembrane transporter activity
AW20_RS26885	COG1136	(ABC) transporter
AW20_RS26900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AW20_RS26905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AW20_RS26915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AW20_RS26920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS26935	COG1476	TRANSCRIPTIONal
AW20_RS26960	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AW20_RS26990	COG3850	Histidine kinase
AW20_RS26990	COG5002	protein histidine kinase activity
AW20_RS26995	COG0745	RESPONSE REGULATOR receiver
AW20_RS27020	COG2814	Major facilitator Superfamily
AW20_RS27065	COG2169	Transcriptional regulator
AW20_RS27090	COG0346	lactoylglutathione lyase activity
AW20_RS27105	COG1522	sequence-specific DNA binding
AW20_RS27120	COG0443	Heat shock 70 kDa protein
AW20_RS27135	COG0640	Transcriptional regulator
AW20_RS27140	COG0346	lactoylglutathione lyase activity
AW20_RS27145	COG0798	PFAM Bile acid sodium symporter
AW20_RS27175	COG1121	(ABC) transporter
AW20_RS27180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AW20_RS27185	COG0803	Belongs to the bacterial solute-binding protein 9 family
AW20_RS27190	COG2267	carboxylic ester hydrolase activity
AW20_RS27195	COG1575	Belongs to the MenA family. Type 1 subfamily
AW20_RS27205	COG5609	conserved protein (DUF2294)
AW20_RS27210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AW20_RS27220	COG0288	reversible hydration of carbon dioxide
AW20_RS27225	COG0415	Belongs to the DNA photolyase family
AW20_RS27270	COG0583	DNA-binding transcription factor activity
AW20_RS27295	COG1335	isochorismatase
AW20_RS27300	COG2267	carboxylic ester hydrolase activity
AW20_RS27305	COG0753	catalase activity
AW20_RS27310	COG0737	Belongs to the 5'-nucleotidase family
AW20_RS27340	COG2066	Belongs to the glutaminase family
AW20_RS27350	COG0784	Response regulator, receiver
AW20_RS27360	COG0531	amino acid
AW20_RS27380	COG0281	malic enzyme
AW20_RS27390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_RS27395	COG1114	Component of the transport system for branched-chain amino acids
AW20_RS27400	COG0531	amino acid
AW20_RS27405	COG0322	excinuclease ABC activity
AW20_RS27415	COG1396	sequence-specific DNA binding
AW20_RS27420	COG0252	asparaginase activity
AW20_RS27425	COG1027	Aspartate ammonia-lyase
AW20_RS27440	COG1063	alcohol dehydrogenase
AW20_RS27475	COG1280	lysine exporter protein (LysE YggA)
AW20_RS27480	COG3403	YqcI/YcgG family
AW20_RS27485	COG5577	PFAM Coat F domain
AW20_RS27500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AW20_RS27505	COG0574	Belongs to the PEP-utilizing enzyme family
AW20_RS27505	COG3848	Pyruvate phosphate dikinase
AW20_RS27520	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AW20_RS27555	COG1960	acyl-CoA dehydrogenase activity
AW20_RS27565	COG0640	Transcriptional regulator
AW20_RS27570	COG0860	N-Acetylmuramoyl-L-alanine amidase
AW20_RS27585	COG1414	Transcriptional regulator
AW20_RS27590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AW20_RS27595	COG1984	allophanate hydrolase subunit 2
AW20_RS27630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AW20_RS27680	COG4335	DNA alkylation repair
AW20_RS27690	COG0833	amino acid
AW20_RS27700	COG0730	response to heat
AW20_RS27730	COG0596	Alpha beta hydrolase
AW20_RS27735	COG0745	RESPONSE REGULATOR receiver
AW20_RS27740	COG0642	Histidine kinase
AW20_RS27760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AW20_RS27780	COG0456	acetyltransferase
AW20_RS27785	COG2207	Transcriptional regulator
AW20_RS27810	COG0577	efflux transmembrane transporter activity
AW20_RS27810	COG1136	(ABC) transporter
AW20_RS27820	COG1725	Transcriptional regulator
AW20_RS27855	COG1846	Transcriptional regulator
AW20_RS27860	COG0778	Nitroreductase
AW20_RS27870	COG0714	Associated with various cellular activities
AW20_RS27895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AW20_RS27905	COG0753	catalase activity
AW20_RS27910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AW20_RS27920	COG0463	Glycosyl transferase, family 2
AW20_RS27945	COG0463	Glycosyl transferase, family 2
AW20_RS27970	COG0714	Associated with various cellular activities
AW20_RS27990	COG0346	lactoylglutathione lyase activity
AW20_RS27995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AW20_RS28005	COG3279	Response regulator of the LytR AlgR family
AW20_RS28015	COG4377	Putative membrane peptidase family (DUF2324)
AW20_RS28030	COG3655	Transcriptional regulator
AW20_RS28040	COG1785	Belongs to the alkaline phosphatase family
AW20_RS28045	COG3239	Fatty acid desaturase
AW20_RS28050	COG1690	Belongs to the RtcB family
AW20_RS28055	COG0833	amino acid
AW20_RS28060	COG1414	Transcriptional regulator
AW20_RS28065	COG4187	Peptidase family M20/M25/M40
AW20_RS28070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AW20_RS28075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AW20_RS28085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AW20_RS28105	COG2329	Antibiotic biosynthesis monooxygenase
AW20_RS28140	COG2390	Transcriptional regulator
AW20_RS28150	COG1172	Belongs to the binding-protein-dependent transport system permease family
AW20_RS28160	COG1879	ABC-type sugar transport system periplasmic component
AW20_RS28185	COG1595	DNA-templated transcription, initiation
AW20_RS28195	COG1388	LysM domain
AW20_RS28195	COG3584	3D domain protein
AW20_RS28230	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AW20_RS28230	COG1605	Chorismate mutase
AW20_RS28235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AW20_RS28240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AW20_RS28245	COG0287	Prephenate dehydrogenase
AW20_RS28260	COG1309	transcriptional regulator
AW20_RS28265	COG1033	growth of symbiont in host cell
AW20_RS28265	COG2409	Drug exporters of the RND superfamily
AW20_RS28275	COG1033	growth of symbiont in host cell
AW20_RS28275	COG2409	Drug exporters of the RND superfamily
AW20_RS28285	COG0488	(ABC) transporter
AW20_RS28290	COG1368	sulfuric ester hydrolase activity
AW20_RS28295	COG0861	Integral membrane protein TerC family
AW20_RS28315	COG4912	Dna alkylation repair
AW20_RS28335	COG2318	DinB family
AW20_RS28340	COG0697	spore germination
AW20_RS28365	COG2746	aminoglycoside 3-N-acetyltransferase activity
AW20_RS28405	COG1116	anion transmembrane transporter activity
AW20_RS28410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AW20_RS28415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AW20_RS28420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AW20_RS28435	COG0628	permease
AW20_RS28510	COG5146	pantothenate kinase activity
AW20_RS28515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AW20_RS28520	COG0436	Aminotransferase
AW20_RS28555	COG2226	methyltransferase
AW20_RS28570	COG2261	transglycosylase associated protein
AW20_RS28590	COG0477	Major facilitator Superfamily
AW20_RS28590	COG2814	Major facilitator Superfamily
AW20_RS28595	COG4533	DNA binding
AW20_RS28600	COG0789	Transcriptional regulator
AW20_RS28605	COG1664	Polymer-forming cytoskeletal
AW20_RS28615	COG2814	Major facilitator Superfamily
AW20_RS28635	COG1307	EDD domain protein, DegV family
AW20_RS28640	COG1164	Oligoendopeptidase f
AW20_RS28680	COG5002	protein histidine kinase activity
AW20_RS28685	COG2936	dipeptidyl-peptidase activity
AW20_RS28725	COG4948	Mandelate Racemase Muconate Lactonizing
AW20_RS28735	COG4166	transmembrane transport
AW20_RS28740	COG0519	Catalyzes the synthesis of GMP from XMP
AW20_RS28745	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AW20_RS28760	COG0586	Pfam SNARE associated Golgi protein
AW20_RS28800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AW20_RS28805	COG3938	Belongs to the proline racemase family
AW20_RS28815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AW20_RS28820	COG1012	belongs to the aldehyde dehydrogenase family
AW20_RS29655	COG2376	Dihydroxyacetone kinase
AW20_RS29675	COG0322	excinuclease ABC activity
AW20_RS30625	COG1846	Transcriptional regulator
AW20_RS31215	COG1033	growth of symbiont in host cell
AW20_RS31215	COG2409	Drug exporters of the RND superfamily
AW20_RS31225	COG2002	toxin-antitoxin pair type II binding