locus-tag	class	description
FNB21_RS00215	COG1396	sequence-specific DNA binding
FNB21_RS00230	COG3655	Transcriptional regulator
FNB21_RS00260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNB21_RS00285	COG2226	methyltransferase
FNB21_RS00290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNB21_RS00305	COG4152	abc transporter atp-binding protein
FNB21_RS00310	COG1668	transmembrane transport
FNB21_RS00335	COG1794	racemase activity, acting on amino acids and derivatives
FNB21_RS00340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS00345	COG0697	spore germination
FNB21_RS00360	COG4549	nuclear export factor GLE1
FNB21_RS00365	COG2372	response to copper ion
FNB21_RS00365	COG1276	copper resistance
FNB21_RS00370	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNB21_RS00375	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNB21_RS00385	COG0697	spore germination
FNB21_RS00405	COG2205	protein histidine kinase activity
FNB21_RS00410	COG0745	RESPONSE REGULATOR receiver
FNB21_RS00415	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS00475	COG3883	PFAM NLP P60 protein
FNB21_RS00475	COG0791	NLP P60 protein
FNB21_RS00485	COG0741	lytic transglycosylase activity
FNB21_RS00485	COG0791	NLP P60 protein
FNB21_RS00555	COG1396	sequence-specific DNA binding
FNB21_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNB21_RS00660	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS00665	COG5002	protein histidine kinase activity
FNB21_RS00675	COG0586	Pfam SNARE associated Golgi protein
FNB21_RS00685	COG0745	RESPONSE REGULATOR receiver
FNB21_RS00725	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FNB21_RS00730	COG4413	Urea transporter
FNB21_RS00735	COG0831	urea catabolic process
FNB21_RS00740	COG0832	Belongs to the urease beta subunit family
FNB21_RS00750	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FNB21_RS00755	COG0830	nickel cation binding
FNB21_RS00760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNB21_RS00770	COG1695	Transcriptional regulator
FNB21_RS00785	COG0456	acetyltransferase
FNB21_RS00840	COG3545	Serine hydrolase
FNB21_RS00860	COG2814	Major facilitator Superfamily
FNB21_RS00865	COG1082	Xylose isomerase domain protein TIM barrel
FNB21_RS00870	COG1082	Xylose isomerase domain protein TIM barrel
FNB21_RS00875	COG0673	inositol 2-dehydrogenase activity
FNB21_RS00880	COG1609	Transcriptional regulator
FNB21_RS00885	COG1349	DNA-binding transcription factor activity
FNB21_RS00890	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS00895	COG3718	enzyme involved in inositol metabolism
FNB21_RS00900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNB21_RS00905	COG3962	Belongs to the TPP enzyme family
FNB21_RS00910	COG0191	fructose-bisphosphate aldolase activity
FNB21_RS00925	COG1252	NADH dehydrogenase
FNB21_RS00935	COG2814	Major facilitator Superfamily
FNB21_RS00940	COG0583	DNA-binding transcription factor activity
FNB21_RS00950	COG1902	pentaerythritol trinitrate reductase activity
FNB21_RS00955	COG0789	Transcriptional regulator
FNB21_RS00960	COG0697	spore germination
FNB21_RS00965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNB21_RS00975	COG3469	chitinase activity
FNB21_RS00990	COG0672	)-iron permease
FNB21_RS01020	COG0110	maltose O-acetyltransferase activity
FNB21_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNB21_RS01040	COG0395	ABC-type sugar transport system, permease component
FNB21_RS01045	COG1175	transmembrane transport
FNB21_RS01055	COG1609	Transcriptional regulator
FNB21_RS01070	COG2910	NAD(P)H-binding
FNB21_RS01075	COG1733	regulation of RNA biosynthetic process
FNB21_RS01095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNB21_RS01100	COG0531	amino acid
FNB21_RS01120	COG1278	Cold shock
FNB21_RS01125	COG0604	alcohol dehydrogenase
FNB21_RS01160	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FNB21_RS01205	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FNB21_RS01220	COG1393	Belongs to the ArsC family
FNB21_RS01225	COG1464	Belongs to the NlpA lipoprotein family
FNB21_RS01235	COG0583	DNA-binding transcription factor activity
FNB21_RS01255	COG2814	Major facilitator Superfamily
FNB21_RS01270	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS01285	COG5583	Uncharacterized small protein (DUF2292)
FNB21_RS01340	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS01345	COG1733	regulation of RNA biosynthetic process
FNB21_RS01350	COG5553	Cysteine dioxygenase type I
FNB21_RS01360	COG2318	DinB family
FNB21_RS01430	COG2207	Transcriptional regulator
FNB21_RS01440	COG1228	amidohydrolase
FNB21_RS01445	COG0010	Belongs to the arginase family
FNB21_RS01450	COG2271	Major facilitator Superfamily
FNB21_RS01455	COG0477	Major facilitator Superfamily
FNB21_RS01460	COG2986	histidine ammonia-lyase
FNB21_RS01480	COG3773	Cell wall hydrolase
FNB21_RS01485	COG2261	transglycosylase associated protein
FNB21_RS01490	COG1994	Peptidase M50
FNB21_RS01510	COG0252	asparaginase activity
FNB21_RS01520	COG1027	Aspartate ammonia-lyase
FNB21_RS01535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS01560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNB21_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS01575	COG3321	synthase
FNB21_RS01575	COG0604	alcohol dehydrogenase
FNB21_RS01625	COG0822	iron-sulfur transferase activity
FNB21_RS01640	COG2072	flavoprotein involved in K transport
FNB21_RS01645	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS01680	COG0531	amino acid
FNB21_RS01690	COG1114	Component of the transport system for branched-chain amino acids
FNB21_RS01705	COG0531	amino acid
FNB21_RS01720	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNB21_RS01730	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS01755	COG1233	COG1233 Phytoene dehydrogenase and related
FNB21_RS01805	COG0804	urea catabolic process
FNB21_RS01815	COG0831	urea catabolic process
FNB21_RS01820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNB21_RS01825	COG1388	LysM domain
FNB21_RS01825	COG0791	NLP P60 protein
FNB21_RS01830	COG3584	3D domain protein
FNB21_RS01830	COG1388	LysM domain
FNB21_RS01835	COG0778	Nitroreductase
FNB21_RS01840	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNB21_RS01845	COG0586	Pfam SNARE associated Golgi protein
FNB21_RS01855	COG0400	carboxylic ester hydrolase activity
FNB21_RS01860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNB21_RS01865	COG2244	polysaccharide biosynthetic process
FNB21_RS01870	COG0697	spore germination
FNB21_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS01895	COG1132	(ABC) transporter
FNB21_RS01920	COG4195	phage-related replication protein
FNB21_RS01930	COG0783	Belongs to the Dps family
FNB21_RS01940	COG5577	PFAM Coat F domain
FNB21_RS01945	COG1253	flavin adenine dinucleotide binding
FNB21_RS01960	COG0516	GMP reductase activity
FNB21_RS01960	COG0517	IMP dehydrogenase activity
FNB21_RS01970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNB21_RS01970	COG0723	plastoquinol--plastocyanin reductase activity
FNB21_RS01985	COG0287	Prephenate dehydrogenase
FNB21_RS01995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FNB21_RS01995	COG1605	Chorismate mutase
FNB21_RS02005	COG2059	Chromate
FNB21_RS02020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNB21_RS02025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNB21_RS02030	COG2508	Transcriptional regulator
FNB21_RS02035	COG0011	TIGRFAM Protein of
FNB21_RS02040	COG0791	NLP P60 protein
FNB21_RS02040	COG1388	LysM domain
FNB21_RS02045	COG0753	catalase activity
FNB21_RS02055	COG0733	neurotransmitter:sodium symporter activity
FNB21_RS02100	COG0730	response to heat
FNB21_RS02105	COG1902	pentaerythritol trinitrate reductase activity
FNB21_RS02120	COG2205	protein histidine kinase activity
FNB21_RS02130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNB21_RS02160	COG0640	Transcriptional regulator
FNB21_RS02170	COG0778	Nitroreductase
FNB21_RS02190	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNB21_RS02190	COG3103	Sh3 type 3 domain protein
FNB21_RS02190	COG4991	sh3 domain protein
FNB21_RS02195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNB21_RS02200	COG2002	toxin-antitoxin pair type II binding
FNB21_RS02205	COG2318	DinB family
FNB21_RS02210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNB21_RS02220	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNB21_RS02225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS02240	COG2211	Major facilitator Superfamily
FNB21_RS02245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS02250	COG1597	lipid kinase activity
FNB21_RS02260	COG0372	Belongs to the citrate synthase family
FNB21_RS02265	COG0583	DNA-binding transcription factor activity
FNB21_RS02270	COG0697	spore germination
FNB21_RS02275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS02295	COG2202	Pas domain
FNB21_RS02295	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS02300	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS02330	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS02335	COG2261	transglycosylase associated protein
FNB21_RS02345	COG0740	serine-type endopeptidase activity
FNB21_RS02360	COG1027	Aspartate ammonia-lyase
FNB21_RS02365	COG0252	asparaginase activity
FNB21_RS02370	COG1396	sequence-specific DNA binding
FNB21_RS02385	COG0640	Transcriptional regulator
FNB21_RS02405	COG0531	amino acid
FNB21_RS02410	COG1959	2 iron, 2 sulfur cluster binding
FNB21_RS02430	COG0281	malic enzyme
FNB21_RS02435	COG2746	aminoglycoside 3-N-acetyltransferase activity
FNB21_RS02445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS02450	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS02460	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNB21_RS02465	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FNB21_RS02475	COG0477	Major facilitator Superfamily
FNB21_RS02480	COG1846	Transcriptional regulator
FNB21_RS02485	COG0789	Transcriptional regulator
FNB21_RS02490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS02525	COG1819	glycosyl
FNB21_RS02545	COG1902	pentaerythritol trinitrate reductase activity
FNB21_RS02555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNB21_RS02570	COG2814	Major facilitator Superfamily
FNB21_RS02580	COG1228	amidohydrolase
FNB21_RS02590	COG1316	TRANSCRIPTIONal
FNB21_RS02595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS02615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FNB21_RS02625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNB21_RS02690	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS02700	COG0531	amino acid
FNB21_RS02715	COG3764	Sortase (surface protein transpeptidase)
FNB21_RS02725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS02730	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FNB21_RS02765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS02780	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FNB21_RS02790	COG0501	Belongs to the peptidase M48B family
FNB21_RS02825	COG0131	Imidazoleglycerol-phosphate dehydratase
FNB21_RS02825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FNB21_RS02840	COG2076	Multidrug Resistance protein
FNB21_RS02845	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNB21_RS02850	COG1278	Cold shock
FNB21_RS02855	COG2323	membrane
FNB21_RS02865	COG2910	NAD(P)H-binding
FNB21_RS02890	COG4607	ABC-type enterochelin transport system periplasmic component
FNB21_RS02895	COG4604	ABC transporter, ATP-binding protein
FNB21_RS02900	COG4605	iron ion homeostasis
FNB21_RS02905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS02910	COG3773	Cell wall hydrolase
FNB21_RS02930	COG1063	alcohol dehydrogenase
FNB21_RS02935	COG3775	system Galactitol-specific IIC component
FNB21_RS02940	COG3414	Phosphotransferase system galactitol-specific IIB component
FNB21_RS02945	COG3414	Phosphotransferase system galactitol-specific IIB component
FNB21_RS02960	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS02965	COG0681	Belongs to the peptidase S26 family
FNB21_RS02985	COG1349	DNA-binding transcription factor activity
FNB21_RS03000	COG1193	negative regulation of DNA recombination
FNB21_RS03010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FNB21_RS03015	COG1396	sequence-specific DNA binding
FNB21_RS03020	COG0861	Integral membrane protein TerC family
FNB21_RS03025	COG1609	Transcriptional regulator
FNB21_RS03030	COG1959	2 iron, 2 sulfur cluster binding
FNB21_RS03090	COG3773	Cell wall hydrolase
FNB21_RS03095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNB21_RS03120	COG3546	catalase activity
FNB21_RS03140	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS03145	COG2207	Transcriptional regulator
FNB21_RS03145	COG1917	Cupin 2, conserved barrel domain protein
FNB21_RS03150	COG4585	Histidine kinase
FNB21_RS03170	COG3209	COG3209 Rhs family protein
FNB21_RS03190	COG1819	glycosyl
FNB21_RS03195	COG0456	acetyltransferase
FNB21_RS03210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNB21_RS03220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNB21_RS03240	COG0346	lactoylglutathione lyase activity
FNB21_RS03245	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNB21_RS03260	COG1136	(ABC) transporter
FNB21_RS03265	COG0577	efflux transmembrane transporter activity
FNB21_RS03270	COG3850	Histidine kinase
FNB21_RS03270	COG5002	protein histidine kinase activity
FNB21_RS03295	COG5002	protein histidine kinase activity
FNB21_RS03305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNB21_RS03330	COG4989	oxidoreductase activity
FNB21_RS03340	COG0697	spore germination
FNB21_RS03345	COG2207	Transcriptional regulator
FNB21_RS03345	COG1917	Cupin 2, conserved barrel domain protein
FNB21_RS03420	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FNB21_RS03430	COG0583	DNA-binding transcription factor activity
FNB21_RS03440	COG1301	dicarboxylic acid transport
FNB21_RS03445	COG2824	Alkylphosphonate utilization operon protein PhnA
FNB21_RS03475	COG0405	Gamma-glutamyltransferase
FNB21_RS03495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNB21_RS03500	COG4521	taurine ABC transporter
FNB21_RS03505	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FNB21_RS03510	COG2175	clavaminate synthase activity
FNB21_RS03515	COG2814	Major facilitator Superfamily
FNB21_RS03535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS03545	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS03550	COG1063	alcohol dehydrogenase
FNB21_RS03555	COG0745	RESPONSE REGULATOR receiver
FNB21_RS03560	COG0642	Histidine kinase
FNB21_RS03565	COG1136	(ABC) transporter
FNB21_RS03570	COG0577	efflux transmembrane transporter activity
FNB21_RS03580	COG0412	Dienelactone hydrolase
FNB21_RS03585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS03590	COG0730	response to heat
FNB21_RS03595	COG0425	Belongs to the sulfur carrier protein TusA family
FNB21_RS03600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNB21_RS03600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS03605	COG0425	Belongs to the sulfur carrier protein TusA family
FNB21_RS03605	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNB21_RS03620	COG2210	Belongs to the sulfur carrier protein TusA family
FNB21_RS03625	COG0425	Belongs to the sulfur carrier protein TusA family
FNB21_RS03630	COG1937	Protein conserved in bacteria
FNB21_RS03660	COG0583	DNA-binding transcription factor activity
FNB21_RS03675	COG2188	Transcriptional regulator
FNB21_RS03685	COG2723	6-phospho-beta-galactosidase activity
FNB21_RS03710	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS03725	COG0583	DNA-binding transcription factor activity
FNB21_RS03730	COG2814	Major facilitator Superfamily
FNB21_RS03735	COG0346	lactoylglutathione lyase activity
FNB21_RS03750	COG2723	6-phospho-beta-galactosidase activity
FNB21_RS03760	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNB21_RS03775	COG0778	Nitroreductase
FNB21_RS03780	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS03800	COG1704	LemA family
FNB21_RS03805	COG0726	polysaccharide deacetylase
FNB21_RS03820	COG1733	regulation of RNA biosynthetic process
FNB21_RS03825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNB21_RS03835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS03850	COG2304	oxidoreductase activity
FNB21_RS03860	COG0346	lactoylglutathione lyase activity
FNB21_RS03865	COG2808	Putative FMN-binding domain
FNB21_RS03900	COG4807	Protein conserved in bacteria
FNB21_RS03910	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FNB21_RS03920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS03925	COG1278	Cold shock
FNB21_RS03930	COG1278	Cold shock
FNB21_RS03940	COG0747	negative chemotaxis
FNB21_RS03950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNB21_RS03955	COG0444	Belongs to the ABC transporter superfamily
FNB21_RS03960	COG4608	Belongs to the ABC transporter superfamily
FNB21_RS03970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNB21_RS03975	COG1301	dicarboxylic acid transport
FNB21_RS03990	COG0477	Major facilitator Superfamily
FNB21_RS04030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNB21_RS04035	COG0659	secondary active sulfate transmembrane transporter activity
FNB21_RS04045	COG2211	Major facilitator Superfamily
FNB21_RS04050	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FNB21_RS04055	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FNB21_RS04060	COG1691	(AIR) carboxylase
FNB21_RS04065	COG1606	tRNA processing
FNB21_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS04080	COG1904	glucuronate isomerase
FNB21_RS04115	COG2329	Antibiotic biosynthesis monooxygenase
FNB21_RS04155	COG3655	Transcriptional regulator
FNB21_RS04165	COG0583	DNA-binding transcription factor activity
FNB21_RS04170	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS04185	COG1609	Transcriptional regulator
FNB21_RS04190	COG1082	Xylose isomerase domain protein TIM barrel
FNB21_RS04195	COG0673	inositol 2-dehydrogenase activity
FNB21_RS04215	COG3718	enzyme involved in inositol metabolism
FNB21_RS04220	COG3962	Belongs to the TPP enzyme family
FNB21_RS04225	COG1349	DNA-binding transcription factor activity
FNB21_RS04230	COG0191	fructose-bisphosphate aldolase activity
FNB21_RS04235	COG1082	Xylose isomerase domain protein TIM barrel
FNB21_RS04240	COG2814	Major facilitator Superfamily
FNB21_RS04255	COG1064	alcohol dehydrogenase
FNB21_RS04260	COG0789	Transcriptional regulator
FNB21_RS04275	COG0662	Cupin 2, conserved barrel domain protein
FNB21_RS04295	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS04300	COG1278	Cold shock
FNB21_RS04305	COG1876	peptidase activity
FNB21_RS04325	COG0598	Magnesium transport protein CorA
FNB21_RS04330	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS04340	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS04360	COG4335	DNA alkylation repair
FNB21_RS04365	COG0454	-acetyltransferase
FNB21_RS04385	COG2814	Major facilitator Superfamily
FNB21_RS04390	COG0574	Belongs to the PEP-utilizing enzyme family
FNB21_RS04390	COG3848	Pyruvate phosphate dikinase
FNB21_RS04395	COG3848	Pyruvate phosphate dikinase
FNB21_RS04395	COG0574	Belongs to the PEP-utilizing enzyme family
FNB21_RS04410	COG2186	Transcriptional regulator
FNB21_RS04430	COG3619	membrane
FNB21_RS04440	COG1349	DNA-binding transcription factor activity
FNB21_RS04445	COG0561	phosphatase activity
FNB21_RS04455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNB21_RS04475	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS04500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNB21_RS04515	COG2814	Major facilitator Superfamily
FNB21_RS04520	COG2160	L-arabinose isomerase activity
FNB21_RS04535	COG1609	Transcriptional regulator
FNB21_RS04540	COG1078	dGTPase activity
FNB21_RS04560	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FNB21_RS04565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FNB21_RS04570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FNB21_RS04570	COG1918	ferrous iron import across plasma membrane
FNB21_RS04595	COG1846	Transcriptional regulator
FNB21_RS04630	COG0697	spore germination
FNB21_RS04635	COG0791	NLP P60 protein
FNB21_RS04635	COG1388	LysM domain
FNB21_RS04640	COG2258	MOSC domain
FNB21_RS04645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNB21_RS04680	COG4974	Belongs to the 'phage' integrase family
FNB21_RS04710	COG1309	transcriptional regulator
FNB21_RS04715	COG3844	kynureninase activity
FNB21_RS04720	COG1113	amino acid transport
FNB21_RS04725	COG3483	tryptophan 2,3-dioxygenase activity
FNB21_RS04730	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FNB21_RS04735	COG1942	4-Oxalocrotonate Tautomerase
FNB21_RS04765	COG0251	oxidation-reduction process
FNB21_RS04780	COG0431	NADPH-dependent FMN reductase
FNB21_RS04785	COG0196	riboflavin kinase activity
FNB21_RS04790	COG2368	4-hydroxyphenylacetate
FNB21_RS04810	COG0789	Transcriptional regulator
FNB21_RS04845	COG5646	InterPro IPR014922
FNB21_RS04850	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FNB21_RS04870	COG2258	MOSC domain
FNB21_RS04885	COG0477	Major facilitator Superfamily
FNB21_RS04890	COG0583	DNA-binding transcription factor activity
FNB21_RS04895	COG2070	2-Nitropropane dioxygenase
FNB21_RS04900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNB21_RS04910	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS04940	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS04945	COG2188	Transcriptional regulator
FNB21_RS04955	COG1501	Belongs to the glycosyl hydrolase 31 family
FNB21_RS04965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNB21_RS04975	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FNB21_RS04985	COG0300	oxidoreductase activity
FNB21_RS04995	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNB21_RS04995	COG0596	Alpha beta hydrolase
FNB21_RS05000	COG1309	transcriptional regulator
FNB21_RS05005	COG1733	regulation of RNA biosynthetic process
FNB21_RS05010	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS05015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNB21_RS05020	COG2226	methyltransferase
FNB21_RS05035	COG1942	4-Oxalocrotonate Tautomerase
FNB21_RS05040	COG0583	DNA-binding transcription factor activity
FNB21_RS05060	COG2267	carboxylic ester hydrolase activity
FNB21_RS05070	COG1335	isochorismatase
FNB21_RS05080	COG0346	lactoylglutathione lyase activity
FNB21_RS05085	COG2259	Doxx family
FNB21_RS05090	COG0039	L-malate dehydrogenase activity
FNB21_RS05095	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FNB21_RS05100	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FNB21_RS05120	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS05120	COG1454	alcohol dehydrogenase
FNB21_RS05130	COG4302	ethanolamine ammonia-lyase activity
FNB21_RS05135	COG4303	Ethanolamine ammonia lyase large subunit
FNB21_RS05145	COG4917	ethanolamine utilization protein
FNB21_RS05155	COG3192	ethanolamine utilization protein
FNB21_RS05185	COG1309	transcriptional regulator
FNB21_RS05190	COG2076	Multidrug Resistance protein
FNB21_RS05220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNB21_RS05230	COG2851	Citrate transporter
FNB21_RS05240	COG0477	Major facilitator Superfamily
FNB21_RS05250	COG0477	Major facilitator Superfamily
FNB21_RS05255	COG1309	transcriptional regulator
FNB21_RS05270	COG2318	DinB family
FNB21_RS05275	COG0156	8-amino-7-oxononanoate synthase activity
FNB21_RS05280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FNB21_RS05295	COG1378	Sugar-specific transcriptional regulator TrmB
FNB21_RS05300	COG0697	spore germination
FNB21_RS05310	COG0583	DNA-binding transcription factor activity
FNB21_RS05345	COG1266	CAAX protease self-immunity
FNB21_RS05365	COG0252	asparaginase activity
FNB21_RS05385	COG1695	Transcriptional regulator
FNB21_RS05390	COG0656	L-ascorbic acid biosynthetic process
FNB21_RS05400	COG0583	DNA-binding transcription factor activity
FNB21_RS05415	COG2814	Major facilitator Superfamily
FNB21_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS05440	COG1309	transcriptional regulator
FNB21_RS05560	COG3339	Conserved Protein
FNB21_RS05575	COG3708	Transcriptional regulator
FNB21_RS05575	COG2207	Transcriptional regulator
FNB21_RS05590	COG1357	PFAM Pentapeptide repeats (8 copies)
FNB21_RS05600	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS05605	COG1733	regulation of RNA biosynthetic process
FNB21_RS05645	COG0303	'Molybdopterin
FNB21_RS05655	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNB21_RS05660	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNB21_RS05665	COG1079	Belongs to the binding-protein-dependent transport system permease family
FNB21_RS05670	COG4603	Belongs to the binding-protein-dependent transport system permease family
FNB21_RS05675	COG3845	ABC transporter
FNB21_RS05700	COG2828	Protein conserved in bacteria
FNB21_RS05705	COG0583	DNA-binding transcription factor activity
FNB21_RS05710	COG2851	Citrate transporter
FNB21_RS05725	COG0670	Belongs to the BI1 family
FNB21_RS05745	COG0791	NLP P60 protein
FNB21_RS05750	COG2814	Major facilitator Superfamily
FNB21_RS05755	COG1846	Transcriptional regulator
FNB21_RS05775	COG1278	Cold shock
FNB21_RS05790	COG1113	amino acid transport
FNB21_RS05795	COG1113	amino acid transport
FNB21_RS05800	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS05805	COG0506	proline dehydrogenase activity
FNB21_RS05810	COG3878	Protein conserved in bacteria
FNB21_RS05825	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNB21_RS05830	COG5001	Diguanylate cyclase
FNB21_RS05830	COG3300	MHYT domain
FNB21_RS05880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FNB21_RS05885	COG5609	conserved protein (DUF2294)
FNB21_RS05895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNB21_RS05920	COG0454	-acetyltransferase
FNB21_RS05935	COG0789	Transcriptional regulator
FNB21_RS05940	COG0667	Aldo Keto reductase
FNB21_RS05950	COG0789	Transcriptional regulator
FNB21_RS05975	COG1621	beta-fructofuranosidase activity
FNB21_RS05980	COG4980	gas vesicle protein
FNB21_RS06005	COG1752	Esterase of the alpha-beta hydrolase superfamily
FNB21_RS06010	COG0577	efflux transmembrane transporter activity
FNB21_RS06015	COG1136	(ABC) transporter
FNB21_RS06025	COG0642	Histidine kinase
FNB21_RS06040	COG1289	transmembrane transporter activity
FNB21_RS06045	COG1937	Protein conserved in bacteria
FNB21_RS06050	COG3209	COG3209 Rhs family protein
FNB21_RS06060	COG3973	AAA domain
FNB21_RS06065	COG1024	Enoyl-CoA hydratase
FNB21_RS06070	COG1733	regulation of RNA biosynthetic process
FNB21_RS06085	COG2124	cytochrome p450
FNB21_RS06090	COG2259	Doxx family
FNB21_RS06095	COG0463	Glycosyl transferase, family 2
FNB21_RS06105	COG0463	Glycosyl transferase, family 2
FNB21_RS06120	COG1388	LysM domain
FNB21_RS06120	COG0791	NLP P60 protein
FNB21_RS06125	COG0840	transmembrane signaling receptor activity
FNB21_RS06130	COG1846	Transcriptional regulator
FNB21_RS06140	COG1595	DNA-templated transcription, initiation
FNB21_RS06145	COG0726	polysaccharide deacetylase
FNB21_RS06170	COG0833	amino acid
FNB21_RS06180	COG0405	Gamma-glutamyltransferase
FNB21_RS06200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNB21_RS06205	COG0569	domain protein
FNB21_RS06215	COG1522	sequence-specific DNA binding
FNB21_RS06225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNB21_RS06230	COG0745	RESPONSE REGULATOR receiver
FNB21_RS06235	COG2770	Histidine kinase
FNB21_RS06235	COG2205	protein histidine kinase activity
FNB21_RS06240	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FNB21_RS06245	COG1607	acyl-coa hydrolase
FNB21_RS06250	COG1802	Transcriptional regulator
FNB21_RS06255	COG0697	spore germination
FNB21_RS06265	COG0006	proline dipeptidase activity
FNB21_RS06285	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS06290	COG5522	Integral membrane protein (intg_mem_TP0381)
FNB21_RS06300	COG1125	glycine betaine transport
FNB21_RS06300	COG0517	IMP dehydrogenase activity
FNB21_RS06315	COG2814	Major facilitator Superfamily
FNB21_RS06325	COG0395	ABC-type sugar transport system, permease component
FNB21_RS06345	COG1609	Transcriptional regulator
FNB21_RS06350	COG2205	protein histidine kinase activity
FNB21_RS06355	COG0730	response to heat
FNB21_RS06360	COG1301	dicarboxylic acid transport
FNB21_RS06375	COG0753	catalase activity
FNB21_RS06400	COG1368	sulfuric ester hydrolase activity
FNB21_RS06410	COG0697	spore germination
FNB21_RS06415	COG1902	pentaerythritol trinitrate reductase activity
FNB21_RS06430	COG1113	amino acid transport
FNB21_RS06435	COG5505	Protein of unknown function (DUF819)
FNB21_RS06440	COG1309	transcriptional regulator
FNB21_RS06450	COG0583	DNA-binding transcription factor activity
FNB21_RS06455	COG0730	response to heat
FNB21_RS06465	COG2910	NAD(P)H-binding
FNB21_RS06470	COG1285	pathogenesis
FNB21_RS06475	COG2226	methyltransferase
FNB21_RS06480	COG4195	phage-related replication protein
FNB21_RS06485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS06500	COG1113	amino acid transport
FNB21_RS06530	COG0463	Glycosyl transferase, family 2
FNB21_RS06550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNB21_RS06555	COG2514	catechol 2,3-dioxygenase activity
FNB21_RS06575	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS06580	COG1115	amino acid carrier protein
FNB21_RS06590	COG0385	Bile acid
FNB21_RS06595	COG0668	transmembrane transport
FNB21_RS06600	COG2340	Cysteine-rich secretory protein family
FNB21_RS06605	COG1253	flavin adenine dinucleotide binding
FNB21_RS06615	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNB21_RS06620	COG0589	response to stress
FNB21_RS06625	COG0205	6-phosphofructokinase activity
FNB21_RS06630	COG1388	LysM domain
FNB21_RS06630	COG0791	NLP P60 protein
FNB21_RS06640	COG0432	Pfam Uncharacterised protein family UPF0047
FNB21_RS06645	COG0697	spore germination
FNB21_RS06650	COG0814	amino acid
FNB21_RS06675	COG1131	(ABC) transporter
FNB21_RS06690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS06705	COG0584	glycerophosphoryl diester phosphodiesterase
FNB21_RS06715	COG1131	(ABC) transporter
FNB21_RS06730	COG0706	membrane insertase activity
FNB21_RS06740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS06740	COG1263	PTS System
FNB21_RS06750	COG2190	(PTS) system
FNB21_RS06755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNB21_RS06770	COG0772	Belongs to the SEDS family
FNB21_RS06775	COG0659	secondary active sulfate transmembrane transporter activity
FNB21_RS06780	COG0813	purine-nucleoside phosphorylase activity
FNB21_RS06790	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS06795	COG4326	sporulation control protein
FNB21_RS06800	COG0515	serine threonine protein kinase
FNB21_RS06825	COG4479	Belongs to the UPF0346 family
FNB21_RS06835	COG3594	Acyltransferase
FNB21_RS06850	COG1509	lysine 2,3-aminomutase activity
FNB21_RS06855	COG0456	acetyltransferase
FNB21_RS06860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNB21_RS06865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNB21_RS06870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNB21_RS06875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNB21_RS06890	COG4191	Histidine kinase
FNB21_RS06915	COG2755	lipolytic protein G-D-S-L family
FNB21_RS06920	COG1999	signal sequence binding
FNB21_RS06930	COG1307	EDD domain protein, DegV family
FNB21_RS06940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNB21_RS06950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FNB21_RS06960	COG0788	formyltetrahydrofolate deformylase activity
FNB21_RS06990	COG0076	glutamate decarboxylase activity
FNB21_RS07010	COG0415	Belongs to the DNA photolyase family
FNB21_RS07015	COG3852	Histidine kinase
FNB21_RS07030	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS07050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNB21_RS07060	COG4846	Membrane protein involved in cytochrome C biogenesis
FNB21_RS07065	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FNB21_RS07070	COG0785	Cytochrome C biogenesis protein
FNB21_RS07080	COG1132	(ABC) transporter
FNB21_RS07085	COG1132	(ABC) transporter
FNB21_RS07105	COG4224	UPF0291 protein
FNB21_RS07110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNB21_RS07135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNB21_RS07140	COG0531	amino acid
FNB21_RS07150	COG0174	glutamine synthetase
FNB21_RS07155	COG0789	Transcriptional regulator
FNB21_RS07160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FNB21_RS07165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNB21_RS07185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNB21_RS07195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNB21_RS07200	COG0531	amino acid
FNB21_RS07210	COG4550	Control of competence regulator ComK, YlbF/YmcA
FNB21_RS07215	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNB21_RS07220	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNB21_RS07225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNB21_RS07225	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNB21_RS07235	COG2359	stage V sporulation protein S
FNB21_RS07240	COG1692	metallophosphoesterase
FNB21_RS07250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNB21_RS07255	COG1546	Belongs to the CinA family
FNB21_RS07255	COG1058	Belongs to the CinA family
FNB21_RS07260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNB21_RS07280	COG0300	oxidoreductase activity
FNB21_RS07285	COG0612	Peptidase, M16
FNB21_RS07290	COG0612	Peptidase, M16
FNB21_RS07295	COG1079	Belongs to the binding-protein-dependent transport system permease family
FNB21_RS07300	COG4603	Belongs to the binding-protein-dependent transport system permease family
FNB21_RS07310	COG1744	ABC transporter substrate-binding protein PnrA-like
FNB21_RS07315	COG2188	Transcriptional regulator
FNB21_RS07320	COG1674	ftsk spoiiie
FNB21_RS07320	COG4980	gas vesicle protein
FNB21_RS07330	COG0740	serine-type endopeptidase activity
FNB21_RS07335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNB21_RS07350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNB21_RS07355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNB21_RS07360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNB21_RS07365	COG1873	PFAM PRC-barrel domain
FNB21_RS07370	COG0612	Peptidase, M16
FNB21_RS07375	COG0726	polysaccharide deacetylase
FNB21_RS07380	COG1185	polyribonucleotide nucleotidyltransferase activity
FNB21_RS07385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNB21_RS07390	COG0196	riboflavin kinase activity
FNB21_RS07400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNB21_RS07405	COG1550	Protein conserved in bacteria
FNB21_RS07415	COG1358	cellular component organization or biogenesis
FNB21_RS07420	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FNB21_RS07425	COG0195	Participates in both transcription termination and antitermination
FNB21_RS07430	COG0779	Required for maturation of 30S ribosomal subunits
FNB21_RS07440	COG0442	prolyl-tRNA aminoacylation
FNB21_RS07445	COG0750	zinc metalloprotease
FNB21_RS07455	COG4589	Belongs to the CDS family
FNB21_RS07465	COG0233	cytoplasmic translational termination
FNB21_RS07475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNB21_RS07490	COG1191	sigma factor activity
FNB21_RS07495	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FNB21_RS07500	COG0835	chemotaxis
FNB21_RS07505	COG0643	Histidine kinase
FNB21_RS07505	COG2198	Histidine kinase
FNB21_RS07510	COG2201	protein-glutamate methylesterase activity
FNB21_RS07515	COG0455	bacterial-type flagellum organization
FNB21_RS07520	COG1419	protein localization to endoplasmic reticulum
FNB21_RS07525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FNB21_RS07530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FNB21_RS07540	COG1987	bacterial-type flagellum assembly
FNB21_RS07545	COG1338	Plays a role in the flagellum-specific transport system
FNB21_RS07550	COG3190	flagellar
FNB21_RS07555	COG2201	protein-glutamate methylesterase activity
FNB21_RS07560	COG1776	CheC inhibitor of MCP methylation
FNB21_RS07560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNB21_RS07565	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNB21_RS07575	COG1582	Flagellar protein (FlbD)
FNB21_RS07580	COG4786	Flagellar basal body rod
FNB21_RS07585	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FNB21_RS07605	COG1157	protein secretion by the type III secretion system
FNB21_RS07610	COG1317	bacterial-type flagellum organization
FNB21_RS07615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNB21_RS07620	COG1766	The M ring may be actively involved in energy transduction
FNB21_RS07625	COG1677	Flagellar hook-basal body complex protein FliE
FNB21_RS07630	COG1558	bacterial-type flagellum-dependent cell motility
FNB21_RS07635	COG1815	bacterial-type flagellum-dependent cell motility
FNB21_RS07640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FNB21_RS07645	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNB21_RS07655	COG4974	Belongs to the 'phage' integrase family
FNB21_RS07660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FNB21_RS07665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNB21_RS07670	COG0758	DNA mediated transformation
FNB21_RS07675	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FNB21_RS07680	COG0045	succinate-CoA ligase (ADP-forming) activity
FNB21_RS07700	COG0335	large ribosomal subunit rRNA binding
FNB21_RS07710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNB21_RS07720	COG1837	Belongs to the UPF0109 family
FNB21_RS07725	COG0228	four-way junction DNA binding
FNB21_RS07730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNB21_RS07740	COG0552	protein localization to endoplasmic reticulum
FNB21_RS07745	COG1196	nuclear chromosome segregation
FNB21_RS07750	COG0571	ribonuclease III activity
FNB21_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS07765	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNB21_RS07770	COG0416	fatty acid biosynthetic process
FNB21_RS07775	COG1349	DNA-binding transcription factor activity
FNB21_RS07780	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNB21_RS07785	COG1760	l-serine dehydratase
FNB21_RS07790	COG1760	l-serine dehydratase
FNB21_RS07800	COG1461	Dihydroxyacetone kinase
FNB21_RS07805	COG1302	Protein conserved in bacteria
FNB21_RS07810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNB21_RS07820	COG1564	THIamine pyrophosphokinase
FNB21_RS07825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNB21_RS07830	COG1162	GTPase activity
FNB21_RS07835	COG2815	serine threonine protein kinase
FNB21_RS07835	COG0515	serine threonine protein kinase
FNB21_RS07840	COG0631	protein serine/threonine phosphatase activity
FNB21_RS07850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNB21_RS07850	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNB21_RS07855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNB21_RS07865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FNB21_RS07870	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FNB21_RS07875	COG1758	RNA polymerase activity
FNB21_RS07880	COG0194	GDP metabolic process
FNB21_RS07885	COG2052	Domain of unknown function (DUF370)
FNB21_RS07890	COG1561	YicC-like family, N-terminal region
FNB21_RS07895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNB21_RS07905	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNB21_RS07935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNB21_RS07940	COG0540	Belongs to the ATCase OTCase family
FNB21_RS07950	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FNB21_RS07955	COG0564	pseudouridine synthase activity
FNB21_RS07960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNB21_RS07975	COG3599	regulation of cell shape
FNB21_RS07980	COG2302	S4 RNA-binding domain
FNB21_RS07985	COG0762	integral membrane protein
FNB21_RS07990	COG1799	cell septum assembly
FNB21_RS07995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNB21_RS08005	COG1873	PFAM PRC-barrel domain
FNB21_RS08010	COG1191	sigma factor activity
FNB21_RS08015	COG1191	sigma factor activity
FNB21_RS08025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNB21_RS08030	COG0849	cell division
FNB21_RS08035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FNB21_RS08040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FNB21_RS08045	COG0772	Belongs to the SEDS family
FNB21_RS08050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNB21_RS08055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNB21_RS08060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNB21_RS08065	COG0768	penicillin binding
FNB21_RS08070	COG0768	penicillin binding
FNB21_RS08075	COG4839	cell division protein FtsL
FNB21_RS08085	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FNB21_RS08095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNB21_RS08100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNB21_RS08105	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FNB21_RS08110	COG0439	Biotin carboxylase
FNB21_RS08115	COG0454	-acetyltransferase
FNB21_RS08125	COG1024	Enoyl-CoA hydratase
FNB21_RS08130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNB21_RS08135	COG1399	metal-binding, possibly nucleic acid-binding protein
FNB21_RS08140	COG1323	Belongs to the UPF0348 family
FNB21_RS08145	COG3480	Lon protease (S16) C-terminal proteolytic domain
FNB21_RS08160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNB21_RS08165	COG0742	ribosomal rna small subunit methyltransferase
FNB21_RS08175	COG4471	UPF0298 protein
FNB21_RS08185	COG3679	Belongs to the UPF0342 family
FNB21_RS08205	COG4347	Protein of unknown function (DUF1405)
FNB21_RS08215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNB21_RS08230	COG5582	Belongs to the UPF0302 family
FNB21_RS08235	COG0457	Tetratricopeptide repeat
FNB21_RS08240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNB21_RS08245	COG0287	Prephenate dehydrogenase
FNB21_RS08250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNB21_RS08255	COG0159	tryptophan synthase activity
FNB21_RS08265	COG0135	phosphoribosylanthranilate isomerase activity
FNB21_RS08270	COG0134	indole-3-glycerol-phosphate synthase activity
FNB21_RS08275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNB21_RS08285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNB21_RS08290	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNB21_RS08295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FNB21_RS08300	COG0105	UTP biosynthetic process
FNB21_RS08305	COG0142	geranyltranstransferase activity
FNB21_RS08310	COG2226	methyltransferase
FNB21_RS08315	COG0142	geranyltranstransferase activity
FNB21_RS08325	COG0302	gtp cyclohydrolase
FNB21_RS08330	COG0776	regulation of translation
FNB21_RS08335	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FNB21_RS08370	COG2271	Major facilitator Superfamily
FNB21_RS08375	COG1304	FMN binding
FNB21_RS08380	COG0539	negative regulation of cytoplasmic translation
FNB21_RS08390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNB21_RS08405	COG3773	Cell wall hydrolase
FNB21_RS08405	COG3409	Peptidoglycan-binding domain 1 protein
FNB21_RS08410	COG2339	peptidase activity
FNB21_RS08415	COG0252	asparaginase activity
FNB21_RS08420	COG0492	ferredoxin-NADP+ reductase activity
FNB21_RS08425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNB21_RS08430	COG4862	establishment of competence for transformation
FNB21_RS08435	COG0789	Transcriptional regulator
FNB21_RS08440	COG1408	metallophosphoesterase
FNB21_RS08455	COG1266	CAAX protease self-immunity
FNB21_RS08460	COG0514	ATP-dependent DNA helicase (RecQ)
FNB21_RS08470	COG1141	Ferredoxin
FNB21_RS08475	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FNB21_RS08480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNB21_RS08485	COG0739	heme binding
FNB21_RS08490	COG5002	protein histidine kinase activity
FNB21_RS08495	COG0745	RESPONSE REGULATOR receiver
FNB21_RS08500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNB21_RS08505	COG1333	cytochrome c biogenesis protein
FNB21_RS08510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS08515	COG1187	pseudouridine synthase activity
FNB21_RS08520	COG0700	Nucleoside recognition
FNB21_RS08525	COG2715	membrane protein required for spore maturation
FNB21_RS08530	COG1686	Belongs to the peptidase S11 family
FNB21_RS08535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNB21_RS08540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNB21_RS08550	COG1547	Domain of unknown function (DUF309)
FNB21_RS08560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNB21_RS08565	COG4086	secreted protein
FNB21_RS08575	COG0697	spore germination
FNB21_RS08590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNB21_RS08625	COG1686	Belongs to the peptidase S11 family
FNB21_RS08640	COG4974	Belongs to the 'phage' integrase family
FNB21_RS08650	COG0735	belongs to the Fur family
FNB21_RS08655	COG1300	Membrane
FNB21_RS08660	COG0494	nUDIX hydrolase
FNB21_RS08670	COG0667	Aldo Keto reductase
FNB21_RS08680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNB21_RS08685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNB21_RS08695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNB21_RS08700	COG1073	alpha beta
FNB21_RS08715	COG0300	oxidoreductase activity
FNB21_RS08720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS08725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNB21_RS08730	COG1902	pentaerythritol trinitrate reductase activity
FNB21_RS08740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNB21_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS08750	COG2508	Transcriptional regulator
FNB21_RS08770	COG0167	dihydroorotate dehydrogenase activity
FNB21_RS08770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FNB21_RS08775	COG0493	'glutamate synthase
FNB21_RS08780	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNB21_RS08785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNB21_RS08790	COG0346	lactoylglutathione lyase activity
FNB21_RS08795	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS08800	COG4129	membrane
FNB21_RS08805	COG1126	abc transporter atp-binding protein
FNB21_RS08810	COG0765	amino acid transport
FNB21_RS08815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNB21_RS08825	COG1703	isobutyryl-CoA mutase activity
FNB21_RS08830	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNB21_RS08830	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNB21_RS08835	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNB21_RS08835	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNB21_RS08840	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNB21_RS08845	COG0022	dehydrogenase e1 component
FNB21_RS08850	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNB21_RS08855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNB21_RS08870	COG0280	phosphate acetyltransferase
FNB21_RS08875	COG3290	protein histidine kinase activity
FNB21_RS08875	COG3829	transcription factor binding
FNB21_RS08885	COG0584	glycerophosphoryl diester phosphodiesterase
FNB21_RS08890	COG3093	addiction module antidote protein HigA
FNB21_RS08895	COG3104	oligopeptide transport
FNB21_RS08900	COG0745	RESPONSE REGULATOR receiver
FNB21_RS08905	COG0750	zinc metalloprotease
FNB21_RS08910	COG0497	DNA recombination
FNB21_RS08920	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FNB21_RS08935	COG1722	exodeoxyribonuclease VII activity
FNB21_RS08945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNB21_RS08950	COG1302	Protein conserved in bacteria
FNB21_RS08955	COG0439	Biotin carboxylase
FNB21_RS08960	COG0511	ligase activity, forming carbon-carbon bonds
FNB21_RS09000	COG3854	ATPases associated with a variety of cellular activities
FNB21_RS09010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNB21_RS09015	COG0006	proline dipeptidase activity
FNB21_RS09020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNB21_RS09030	COG3872	metal-dependent enzyme
FNB21_RS09040	COG1752	Esterase of the alpha-beta hydrolase superfamily
FNB21_RS09045	COG1321	iron dependent repressor
FNB21_RS09050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNB21_RS09055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNB21_RS09060	COG0095	Lipoate-protein ligase
FNB21_RS09075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNB21_RS09080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNB21_RS09085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNB21_RS09115	COG4970	Tfp pilus assembly protein FimT
FNB21_RS09120	COG4537	Required for transformation and DNA binding
FNB21_RS09125	COG1459	type II secretion system
FNB21_RS09130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FNB21_RS09135	COG1393	Belongs to the ArsC family
FNB21_RS09145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS09160	COG1940	carbohydrate kinase activity
FNB21_RS09165	COG4483	Protein conserved in bacteria
FNB21_RS09170	COG0457	Tetratricopeptide repeat
FNB21_RS09170	COG0705	Rhomboid family
FNB21_RS09180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNB21_RS09190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNB21_RS09205	COG0704	Plays a role in the regulation of phosphate uptake
FNB21_RS09215	COG0768	penicillin binding
FNB21_RS09220	COG0477	Major facilitator Superfamily
FNB21_RS09255	COG2839	Protein conserved in bacteria
FNB21_RS09265	COG2814	Major facilitator Superfamily
FNB21_RS09270	COG1388	LysM domain
FNB21_RS09275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNB21_RS09280	COG4709	membrane
FNB21_RS09285	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FNB21_RS09290	COG0735	belongs to the Fur family
FNB21_RS09295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNB21_RS09300	COG1121	(ABC) transporter
FNB21_RS09310	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNB21_RS09315	COG0513	Belongs to the DEAD box helicase family
FNB21_RS09325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNB21_RS09330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNB21_RS09335	COG2384	SAM-dependent methyltransferase
FNB21_RS09340	COG2010	Cytochrome c
FNB21_RS09345	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS09350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNB21_RS09355	COG0358	DNA primase activity
FNB21_RS09360	COG1671	Belongs to the UPF0178 family
FNB21_RS09365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FNB21_RS09370	COG0517	IMP dehydrogenase activity
FNB21_RS09385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNB21_RS09390	COG0295	cytidine deaminase activity
FNB21_RS09395	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FNB21_RS09405	COG1480	7TM receptor with intracellular HD hydrolase
FNB21_RS09410	COG1702	phosphate starvation-inducible protein PhoH
FNB21_RS09440	COG1610	YqeY-like protein
FNB21_RS09450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNB21_RS09460	COG2264	protein methyltransferase activity
FNB21_RS09475	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNB21_RS09480	COG1420	regulation of RNA biosynthetic process
FNB21_RS09485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNB21_RS09490	COG0481	GTPase activity
FNB21_RS09500	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FNB21_RS09505	COG0268	Binds directly to 16S ribosomal RNA
FNB21_RS09510	COG1466	dna polymerase III delta subunit
FNB21_RS09520	COG0658	competence protein
FNB21_RS09520	COG2333	competence protein COMEC
FNB21_RS09525	COG2131	deaminase
FNB21_RS09530	COG1555	photosystem II stabilization
FNB21_RS09530	COG1596	polysaccharide export
FNB21_RS09535	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNB21_RS09540	COG2226	methyltransferase
FNB21_RS09545	COG0799	negative regulation of ribosome biogenesis
FNB21_RS09550	COG1713	HD superfamily hydrolase involved in NAD metabolism
FNB21_RS09555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNB21_RS09560	COG1534	Rna-binding protein
FNB21_RS09565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNB21_RS09570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FNB21_RS09575	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FNB21_RS09585	COG0688	phosphatidylethanolamine metabolic process
FNB21_RS09590	COG1183	phosphatidylcholine synthase activity
FNB21_RS09610	COG0626	cystathionine gamma-synthase activity
FNB21_RS09615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNB21_RS09620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNB21_RS09625	COG2226	methyltransferase
FNB21_RS09640	COG0768	penicillin binding
FNB21_RS09645	COG1335	isochorismatase
FNB21_RS09650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNB21_RS09655	COG0572	uridine kinase
FNB21_RS09660	COG0826	peptidase U32
FNB21_RS09665	COG0826	peptidase U32
FNB21_RS09670	COG4122	O-methyltransferase activity
FNB21_RS09680	COG3906	Belongs to the UPF0473 family
FNB21_RS09690	COG4472	Bacterial protein of unknown function (DUF965)
FNB21_RS09700	COG0628	permease
FNB21_RS09715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNB21_RS09725	COG0482	sulfurtransferase activity
FNB21_RS09730	COG1104	cysteine desulfurase activity
FNB21_RS09735	COG1959	2 iron, 2 sulfur cluster binding
FNB21_RS09740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNB21_RS09745	COG0581	inorganic phosphate transmembrane transporter activity
FNB21_RS09750	COG0573	inorganic phosphate transmembrane transporter activity
FNB21_RS09755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNB21_RS09760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FNB21_RS09770	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNB21_RS09775	COG0124	histidyl-tRNA synthetase
FNB21_RS09785	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNB21_RS09790	COG1490	D-aminoacyl-tRNA deacylase activity
FNB21_RS09795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNB21_RS09800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNB21_RS09805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FNB21_RS09805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FNB21_RS09810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNB21_RS09810	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNB21_RS09820	COG2244	polysaccharide biosynthetic process
FNB21_RS09825	COG2323	membrane
FNB21_RS09835	COG1862	Preprotein translocase
FNB21_RS09840	COG0343	queuine tRNA-ribosyltransferase activity
FNB21_RS09845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNB21_RS09855	COG2255	four-way junction helicase activity
FNB21_RS09860	COG0632	four-way junction helicase activity
FNB21_RS09890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNB21_RS09895	COG0157	Belongs to the NadC ModD family
FNB21_RS09900	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNB21_RS09905	COG1104	cysteine desulfurase activity
FNB21_RS09910	COG1827	regulation of RNA biosynthetic process
FNB21_RS09915	COG0077	Prephenate dehydratase
FNB21_RS09920	COG4492	Belongs to the UPF0735 family
FNB21_RS09925	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNB21_RS09930	COG3290	protein histidine kinase activity
FNB21_RS09940	COG2868	ribosomal protein
FNB21_RS09950	COG1530	ribonuclease E activity
FNB21_RS09955	COG1994	Peptidase M50
FNB21_RS09960	COG0739	heme binding
FNB21_RS09965	COG2894	cell division
FNB21_RS09970	COG0850	regulation of cytokinetic process
FNB21_RS09975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FNB21_RS09980	COG1792	Involved in formation and maintenance of cell shape
FNB21_RS09985	COG1077	Cell shape determining protein MreB Mrl
FNB21_RS09990	COG2003	Belongs to the UPF0758 family
FNB21_RS09995	COG0424	maF-like protein
FNB21_RS10005	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FNB21_RS10015	COG2322	membrane
FNB21_RS10020	COG0285	dihydrofolate synthase activity
FNB21_RS10035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FNB21_RS10040	COG1388	LysM domain
FNB21_RS10045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNB21_RS10050	COG0113	porphobilinogen synthase activity
FNB21_RS10055	COG1587	Uroporphyrinogen-III synthase
FNB21_RS10060	COG0181	hydroxymethylbilane synthase activity
FNB21_RS10065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNB21_RS10085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNB21_RS10090	COG1067	ATP-dependent peptidase activity
FNB21_RS10090	COG0470	DNA polymerase III
FNB21_RS10095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNB21_RS10100	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNB21_RS10105	COG0457	Tetratricopeptide repeat
FNB21_RS10105	COG1477	protein flavinylation
FNB21_RS10110	COG0066	3-isopropylmalate dehydratase activity
FNB21_RS10115	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNB21_RS10125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNB21_RS10130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNB21_RS10135	COG0440	acetolactate synthase activity
FNB21_RS10140	COG0028	Belongs to the TPP enzyme family
FNB21_RS10150	COG0622	Phosphoesterase
FNB21_RS10165	COG5401	PFAM Sporulation and spore germination
FNB21_RS10170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNB21_RS10175	COG1846	Transcriptional regulator
FNB21_RS10185	COG0306	phosphate transporter
FNB21_RS10190	COG1392	Phosphate transport regulator
FNB21_RS10205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS10210	COG0431	NADPH-dependent FMN reductase
FNB21_RS10215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNB21_RS10220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNB21_RS10225	COG1116	anion transmembrane transporter activity
FNB21_RS10230	COG0475	glutathione-regulated potassium exporter activity
FNB21_RS10235	COG0490	domain, Protein
FNB21_RS10245	COG2197	response regulator
FNB21_RS10250	COG0824	Thioesterase
FNB21_RS10255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNB21_RS10260	COG1053	succinate dehydrogenase
FNB21_RS10265	COG2009	succinate dehydrogenase
FNB21_RS10270	COG1719	4-vinyl reductase, 4VR
FNB21_RS10275	COG0527	aspartate kinase activity
FNB21_RS10285	COG3118	belongs to the thioredoxin family
FNB21_RS10290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNB21_RS10295	COG2086	electron transfer activity
FNB21_RS10300	COG1024	Enoyl-CoA hydratase
FNB21_RS10305	COG1309	transcriptional regulator
FNB21_RS10310	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS10315	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FNB21_RS10320	COG3766	membrane
FNB21_RS10325	COG1193	negative regulation of DNA recombination
FNB21_RS10330	COG1796	DNA polymerase
FNB21_RS10330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNB21_RS10335	COG1286	toxin biosynthetic process
FNB21_RS10340	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FNB21_RS10345	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNB21_RS10350	COG0072	phenylalanine-tRNA ligase activity
FNB21_RS10350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNB21_RS10355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNB21_RS10360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNB21_RS10370	COG1363	Peptidase, m42
FNB21_RS10390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNB21_RS10395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNB21_RS10400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNB21_RS10405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNB21_RS10415	COG1484	DNA-dependent DNA replication
FNB21_RS10420	COG3611	Membrane attachment protein
FNB21_RS10425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FNB21_RS10435	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FNB21_RS10440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FNB21_RS10445	COG0237	dephospho-CoA kinase activity
FNB21_RS10450	COG1971	Probably functions as a manganese efflux pump
FNB21_RS10455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNB21_RS10460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNB21_RS10460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNB21_RS10465	COG5002	protein histidine kinase activity
FNB21_RS10470	COG0745	RESPONSE REGULATOR receiver
FNB21_RS10480	COG0039	L-malate dehydrogenase activity
FNB21_RS10485	COG0538	isocitrate dehydrogenase activity
FNB21_RS10490	COG0372	Belongs to the citrate synthase family
FNB21_RS10495	COG2707	UPF0756 membrane protein
FNB21_RS10500	COG0628	permease
FNB21_RS10505	COG3030	protein affecting phage T7 exclusion by the F plasmid
FNB21_RS10515	COG0825	malonyl-CoA metabolic process
FNB21_RS10520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FNB21_RS10525	COG2186	Transcriptional regulator
FNB21_RS10530	COG0281	malic enzyme
FNB21_RS10535	COG0587	DNA-directed DNA polymerase activity
FNB21_RS10550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FNB21_RS10560	COG4109	DRTGG domain
FNB21_RS10570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNB21_RS10580	COG0165	Argininosuccinate lyase
FNB21_RS10585	COG0137	argininosuccinate synthase activity
FNB21_RS10600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNB21_RS10605	COG0827	DNA restriction-modification system
FNB21_RS10610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FNB21_RS10615	COG3874	Sporulation protein YtfJ
FNB21_RS10625	COG1714	RDD family
FNB21_RS10630	COG0616	signal peptide processing
FNB21_RS10635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNB21_RS10640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FNB21_RS10650	COG0301	tRNA thio-modification
FNB21_RS10655	COG1104	cysteine desulfurase activity
FNB21_RS10660	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FNB21_RS10665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNB21_RS10670	COG1309	transcriptional regulator
FNB21_RS10675	COG1956	GAF domain-containing protein
FNB21_RS10690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNB21_RS10695	COG0454	-acetyltransferase
FNB21_RS10700	COG0517	IMP dehydrogenase activity
FNB21_RS10705	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNB21_RS10725	COG1605	Chorismate mutase
FNB21_RS10725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FNB21_RS10730	COG3118	belongs to the thioredoxin family
FNB21_RS10735	COG4980	gas vesicle protein
FNB21_RS10750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNB21_RS10760	COG1674	ftsk spoiiie
FNB21_RS10765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNB21_RS10770	COG4848	Belongs to the UPF0354 family
FNB21_RS10775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS10780	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FNB21_RS10785	COG1363	Peptidase, m42
FNB21_RS10790	COG5584	Small secreted protein
FNB21_RS10795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS10800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNB21_RS10810	COG0510	thiamine kinase activity
FNB21_RS10815	COG1523	belongs to the glycosyl hydrolase 13 family
FNB21_RS10825	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FNB21_RS10830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNB21_RS10835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNB21_RS10840	COG1349	DNA-binding transcription factor activity
FNB21_RS10845	COG1187	pseudouridine synthase activity
FNB21_RS10850	COG2244	polysaccharide biosynthetic process
FNB21_RS10855	COG2081	HI0933 family
FNB21_RS10865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FNB21_RS10870	COG0495	leucyl-tRNA aminoacylation
FNB21_RS10880	COG2610	gluconate transmembrane transporter activity
FNB21_RS10885	COG2814	Major facilitator Superfamily
FNB21_RS10900	COG1242	4 iron, 4 sulfur cluster binding
FNB21_RS10905	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FNB21_RS10915	COG2267	carboxylic ester hydrolase activity
FNB21_RS10920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNB21_RS10925	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS10935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNB21_RS10940	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FNB21_RS10950	COG1506	peptidase
FNB21_RS10955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNB21_RS10960	COG1116	anion transmembrane transporter activity
FNB21_RS10965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNB21_RS10970	COG0494	nUDIX hydrolase
FNB21_RS10980	COG4824	toxin secretion phage lysis holin
FNB21_RS10985	COG0783	Belongs to the Dps family
FNB21_RS10995	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNB21_RS11000	COG0288	reversible hydration of carbon dioxide
FNB21_RS11005	COG0523	cobalamin synthesis protein
FNB21_RS11015	COG0254	rRNA binding
FNB21_RS11020	COG1271	oxidase subunit
FNB21_RS11025	COG1294	oxidase, subunit
FNB21_RS11030	COG0716	FMN binding
FNB21_RS11055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNB21_RS11065	COG4948	Mandelate Racemase Muconate Lactonizing
FNB21_RS11070	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS11075	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FNB21_RS11080	COG0596	Alpha beta hydrolase
FNB21_RS11085	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FNB21_RS11090	COG1169	isochorismate synthase
FNB21_RS11095	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNB21_RS11105	COG0058	SHG alpha-glucan phosphorylase activity
FNB21_RS11110	COG0297	glycogen (starch) synthase activity
FNB21_RS11115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNB21_RS11120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNB21_RS11250	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS11255	COG1285	pathogenesis
FNB21_RS11275	COG0529	Catalyzes the synthesis of activated sulfate
FNB21_RS11285	COG0306	phosphate transporter
FNB21_RS11295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FNB21_RS11300	COG0346	lactoylglutathione lyase activity
FNB21_RS11305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNB21_RS11320	COG0166	Belongs to the GPI family
FNB21_RS11330	COG2111	Na H antiporter
FNB21_RS11330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNB21_RS11335	COG2111	Na H antiporter
FNB21_RS11340	COG1006	Multisubunit Na H antiporter MnhC subunit
FNB21_RS11345	COG0651	ATP synthesis coupled electron transport
FNB21_RS11350	COG1863	multisubunit Na H antiporter MnhE subunit
FNB21_RS11355	COG2212	antiporter activity
FNB21_RS11360	COG1320	monovalent cation:proton antiporter activity
FNB21_RS11365	COG1979	alcohol dehydrogenase
FNB21_RS11370	COG2155	Conserved Protein
FNB21_RS11375	COG1098	S1 RNA binding domain
FNB21_RS11380	COG0436	Aminotransferase
FNB21_RS11385	COG1522	sequence-specific DNA binding
FNB21_RS11390	COG2267	carboxylic ester hydrolase activity
FNB21_RS11395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FNB21_RS11400	COG2032	superoxide dismutase activity
FNB21_RS11415	COG5018	Exonuclease
FNB21_RS11420	COG2050	protein possibly involved in aromatic compounds catabolism
FNB21_RS11430	COG1418	mRNA catabolic process
FNB21_RS11440	COG2056	Na+-H+ antiporter family
FNB21_RS11445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNB21_RS11450	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FNB21_RS11455	COG3584	3D domain protein
FNB21_RS11465	COG1252	NADH dehydrogenase
FNB21_RS11470	COG0492	ferredoxin-NADP+ reductase activity
FNB21_RS11480	COG0316	Belongs to the HesB IscA family
FNB21_RS11485	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNB21_RS11490	COG4844	belongs to the
FNB21_RS11495	COG1252	NADH dehydrogenase
FNB21_RS11500	COG4837	Protein of unknown function (DUF1462)
FNB21_RS11505	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FNB21_RS11510	COG0083	homoserine kinase activity
FNB21_RS11515	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNB21_RS11520	COG0460	homoserine dehydrogenase
FNB21_RS11525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNB21_RS11530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FNB21_RS11535	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FNB21_RS11540	COG0647	UMP catabolic process
FNB21_RS11545	COG2445	Protein of unknown function DUF86
FNB21_RS11555	COG4470	Protein conserved in bacteria
FNB21_RS11565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNB21_RS11570	COG0739	heme binding
FNB21_RS11580	COG0733	neurotransmitter:sodium symporter activity
FNB21_RS11590	COG3377	Domain of unknown function (DUF1805)
FNB21_RS11595	COG1801	Protein of unknown function DUF72
FNB21_RS11600	COG0719	Fe-S assembly protein
FNB21_RS11605	COG0822	iron-sulfur transferase activity
FNB21_RS11610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNB21_RS11615	COG0719	Fe-S assembly protein
FNB21_RS11620	COG0396	ATPase activity
FNB21_RS11625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNB21_RS11630	COG1464	Belongs to the NlpA lipoprotein family
FNB21_RS11635	COG2011	ABC-type metal ion transport system permease component
FNB21_RS11640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNB21_RS11645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS11650	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FNB21_RS11660	COG0509	glycine decarboxylation via glycine cleavage system
FNB21_RS11665	COG1393	Belongs to the ArsC family
FNB21_RS11670	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS11675	COG0183	Belongs to the thiolase family
FNB21_RS11680	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNB21_RS11680	COG1024	Enoyl-CoA hydratase
FNB21_RS11705	COG1120	ATPase activity
FNB21_RS11715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS11720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNB21_RS11730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNB21_RS11735	COG1309	transcriptional regulator
FNB21_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS11750	COG0477	Major facilitator Superfamily
FNB21_RS11760	COG3850	Histidine kinase
FNB21_RS11760	COG5002	protein histidine kinase activity
FNB21_RS11765	COG0745	RESPONSE REGULATOR receiver
FNB21_RS11770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNB21_RS11775	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS11785	COG1846	Transcriptional regulator
FNB21_RS11790	COG0778	Nitroreductase
FNB21_RS11795	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FNB21_RS11800	COG0314	molybdopterin synthase activity
FNB21_RS11805	COG1763	Mo-molybdopterin cofactor biosynthetic process
FNB21_RS11810	COG0303	'Molybdopterin
FNB21_RS11815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNB21_RS11820	COG0746	molybdenum cofactor guanylyltransferase activity
FNB21_RS11830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FNB21_RS11835	COG5609	conserved protein (DUF2294)
FNB21_RS11840	COG3383	formate dehydrogenase (NAD+) activity
FNB21_RS11845	COG2427	Protein of unknown function (DUF1641)
FNB21_RS11850	COG0725	ABC transporter, periplasmic molybdate-binding protein
FNB21_RS11855	COG4149	molybdate abc transporter
FNB21_RS11865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNB21_RS11870	COG0557	exoribonuclease II activity
FNB21_RS11875	COG1647	Serine aminopeptidase, S33
FNB21_RS11880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNB21_RS11890	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNB21_RS11920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FNB21_RS11940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNB21_RS11950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FNB21_RS11955	COG1660	Displays ATPase and GTPase activities
FNB21_RS11960	COG1051	belongs to the nudix hydrolase family
FNB21_RS11965	COG0492	ferredoxin-NADP+ reductase activity
FNB21_RS11970	COG0457	Tetratricopeptide repeat
FNB21_RS11975	COG0140	phosphoribosyl-ATP diphosphatase activity
FNB21_RS11975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNB21_RS11980	COG0107	imidazoleglycerol-phosphate synthase activity
FNB21_RS11985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNB21_RS11990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNB21_RS11995	COG0131	Imidazoleglycerol-phosphate dehydratase
FNB21_RS12000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNB21_RS12005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNB21_RS12010	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FNB21_RS12015	COG0110	maltose O-acetyltransferase activity
FNB21_RS12020	COG0546	phosphoglycolate phosphatase activity
FNB21_RS12025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNB21_RS12030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FNB21_RS12035	COG1950	PFAM Membrane protein of
FNB21_RS12040	COG1983	PspC domain protein
FNB21_RS12045	COG3595	metallopeptidase activity
FNB21_RS12055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNB21_RS12060	COG0556	nucleotide-excision repair
FNB21_RS12065	COG2204	response regulator
FNB21_RS12070	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS12075	COG0506	proline dehydrogenase activity
FNB21_RS12080	COG4897	Protein conserved in bacteria
FNB21_RS12085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNB21_RS12090	COG3409	Peptidoglycan-binding domain 1 protein
FNB21_RS12090	COG0793	Belongs to the peptidase S41A family
FNB21_RS12095	COG0739	heme binding
FNB21_RS12100	COG2177	Part of the ABC transporter FtsEX involved in
FNB21_RS12105	COG2884	Cell division ATP-binding protein ftsE
FNB21_RS12110	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS12120	COG0805	protein transport
FNB21_RS12125	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNB21_RS12130	COG3540	Alkaline phosphatase
FNB21_RS12140	COG0653	protein targeting
FNB21_RS12145	COG0456	acetyltransferase
FNB21_RS12150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNB21_RS12160	COG1516	flagellar protein fliS
FNB21_RS12165	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FNB21_RS12175	COG1113	amino acid transport
FNB21_RS12185	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS12190	COG1454	alcohol dehydrogenase
FNB21_RS12195	COG1510	regulation of RNA biosynthetic process
FNB21_RS12200	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FNB21_RS12205	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FNB21_RS12210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FNB21_RS12215	COG4786	Flagellar basal body rod
FNB21_RS12215	COG1256	bacterial-type flagellum assembly
FNB21_RS12235	COG1040	competence protein
FNB21_RS12240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FNB21_RS12245	COG1307	EDD domain protein, DegV family
FNB21_RS12250	COG1728	Protein conserved in bacteria
FNB21_RS12260	COG2197	response regulator
FNB21_RS12265	COG4585	Histidine kinase
FNB21_RS12270	COG1739	Uncharacterized protein family UPF0029
FNB21_RS12275	COG1316	TRANSCRIPTIONal
FNB21_RS12280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNB21_RS12285	COG1585	Membrane protein implicated in regulation of membrane protease activity
FNB21_RS12290	COG2268	Band 7 protein
FNB21_RS12295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FNB21_RS12305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNB21_RS12315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FNB21_RS12320	COG0791	NLP P60 protein
FNB21_RS12320	COG1388	LysM domain
FNB21_RS12325	COG0629	single-stranded DNA binding
FNB21_RS12345	COG4786	Flagellar basal body rod
FNB21_RS12355	COG1077	Cell shape determining protein MreB Mrl
FNB21_RS12360	COG1609	Transcriptional regulator
FNB21_RS12365	COG0739	heme binding
FNB21_RS12370	COG2385	sporulation resulting in formation of a cellular spore
FNB21_RS12385	COG4836	Membrane
FNB21_RS12390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNB21_RS12395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNB21_RS12400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNB21_RS12405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNB21_RS12410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNB21_RS12415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNB21_RS12420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNB21_RS12425	COG0356	it plays a direct role in the translocation of protons across the membrane
FNB21_RS12445	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FNB21_RS12450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNB21_RS12465	COG0698	ribose 5-phosphate isomerase
FNB21_RS12475	COG1971	Probably functions as a manganese efflux pump
FNB21_RS12480	COG0009	L-threonylcarbamoyladenylate synthase
FNB21_RS12500	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNB21_RS12515	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNB21_RS12525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNB21_RS12530	COG0191	fructose-bisphosphate aldolase activity
FNB21_RS12535	COG2204	response regulator
FNB21_RS12540	COG4821	SIS domain
FNB21_RS12545	COG0504	CTP synthase activity
FNB21_RS12555	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNB21_RS12555	COG1703	isobutyryl-CoA mutase activity
FNB21_RS12555	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNB21_RS12565	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS12570	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS12575	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNB21_RS12580	COG0183	Belongs to the thiolase family
FNB21_RS12585	COG0247	lactate metabolic process
FNB21_RS12585	COG2181	nitrate reductase activity
FNB21_RS12590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNB21_RS12595	COG4294	response to UV
FNB21_RS12600	COG0018	arginyl-trna synthetase
FNB21_RS12605	COG4506	Protein conserved in bacteria
FNB21_RS12610	COG0010	Belongs to the arginase family
FNB21_RS12615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNB21_RS12620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNB21_RS12630	COG1994	Peptidase M50
FNB21_RS12635	COG1942	4-Oxalocrotonate Tautomerase
FNB21_RS12640	COG3465	dGTPase activity
FNB21_RS12645	COG1078	dGTPase activity
FNB21_RS12650	COG4844	belongs to the
FNB21_RS12660	COG0095	Lipoate-protein ligase
FNB21_RS12665	COG0280	phosphate acetyltransferase
FNB21_RS12670	COG3253	May function as heme-dependent peroxidase
FNB21_RS12675	COG3773	Cell wall hydrolase
FNB21_RS12685	COG2363	Small membrane protein
FNB21_RS12695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNB21_RS12705	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNB21_RS12710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNB21_RS12715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FNB21_RS12715	COG2508	Transcriptional regulator
FNB21_RS12720	COG0686	Belongs to the AlaDH PNT family
FNB21_RS12730	COG0351	phosphomethylpyrimidine kinase
FNB21_RS12735	COG0561	phosphatase activity
FNB21_RS12740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNB21_RS12745	COG2190	(PTS) system
FNB21_RS12745	COG1263	PTS System
FNB21_RS12745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS12755	COG0438	transferase activity, transferring glycosyl groups
FNB21_RS12770	COG2076	Multidrug Resistance protein
FNB21_RS12780	COG0728	peptidoglycan biosynthetic process
FNB21_RS12795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FNB21_RS12800	COG4988	ABC transporter
FNB21_RS12805	COG1294	oxidase, subunit
FNB21_RS12810	COG1271	oxidase subunit
FNB21_RS12815	COG3610	response to peptide
FNB21_RS12820	COG2966	Psort location CytoplasmicMembrane, score
FNB21_RS12825	COG1609	Transcriptional regulator
FNB21_RS12835	COG2814	Major facilitator Superfamily
FNB21_RS12850	COG1966	Carbon starvation protein
FNB21_RS12855	COG0753	catalase activity
FNB21_RS12870	COG0471	metal ion transport
FNB21_RS12875	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNB21_RS12885	COG0745	RESPONSE REGULATOR receiver
FNB21_RS12890	COG5002	protein histidine kinase activity
FNB21_RS12905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNB21_RS12910	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNB21_RS12920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNB21_RS12925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNB21_RS12930	COG4853	Protein conserved in bacteria
FNB21_RS12945	COG0745	RESPONSE REGULATOR receiver
FNB21_RS12970	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNB21_RS12975	COG0305	Participates in initiation and elongation during chromosome replication
FNB21_RS12985	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FNB21_RS12995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNB21_RS13005	COG0360	Binds together with S18 to 16S ribosomal RNA
FNB21_RS13010	COG0012	GTP binding
FNB21_RS13015	COG4481	Protein conserved in bacteria
FNB21_RS13020	COG0668	transmembrane transport
FNB21_RS13035	COG1475	DNA binding
FNB21_RS13040	COG1192	Involved in chromosome partitioning
FNB21_RS13045	COG1475	DNA binding
FNB21_RS13055	COG0445	tRNA wobble uridine modification
FNB21_RS13060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNB21_RS13065	COG1847	R3H domain protein
FNB21_RS13070	COG0706	membrane insertase activity
FNB21_RS13075	COG0594	ribonuclease P activity
FNB21_RS13080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNB21_RS13085	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNB21_RS13090	COG0592	DNA-directed DNA polymerase activity
FNB21_RS13095	COG2501	S4 domain
FNB21_RS13100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNB21_RS13105	COG0187	DNA topoisomerase II activity
FNB21_RS13110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNB21_RS13145	COG0517	IMP dehydrogenase activity
FNB21_RS13145	COG0516	GMP reductase activity
FNB21_RS13160	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FNB21_RS13175	COG1428	Deoxynucleoside kinase
FNB21_RS13180	COG1428	Deoxynucleoside kinase
FNB21_RS13185	COG1388	LysM domain
FNB21_RS13185	COG3858	chitin binding
FNB21_RS13190	COG1335	isochorismatase
FNB21_RS13195	COG0590	tRNA wobble adenosine to inosine editing
FNB21_RS13205	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNB21_RS13210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNB21_RS13215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNB21_RS13320	COG1982	Orn Lys Arg decarboxylase major
FNB21_RS13325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNB21_RS13330	COG3870	Protein conserved in bacteria
FNB21_RS13335	COG0470	DNA polymerase III
FNB21_RS13340	COG1774	PSP1 C-terminal conserved region
FNB21_RS13345	COG4467	Involved in initiation control of chromosome replication
FNB21_RS13350	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FNB21_RS13355	COG2827	Endonuclease containing a URI domain
FNB21_RS13360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNB21_RS13365	COG2002	toxin-antitoxin pair type II binding
FNB21_RS13375	COG0084	hydrolase, TatD family'
FNB21_RS13385	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNB21_RS13395	COG4466	Protein conserved in bacteria
FNB21_RS13410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNB21_RS13415	COG0251	oxidation-reduction process
FNB21_RS13420	COG2088	sporulation resulting in formation of a cellular spore
FNB21_RS13425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNB21_RS13435	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNB21_RS13440	COG0193	aminoacyl-tRNA hydrolase activity
FNB21_RS13450	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNB21_RS13460	COG2002	toxin-antitoxin pair type II binding
FNB21_RS13465	COG2244	polysaccharide biosynthetic process
FNB21_RS13470	COG3956	TIGRFAM MazG family protein
FNB21_RS13475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FNB21_RS13490	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FNB21_RS13495	COG1098	S1 RNA binding domain
FNB21_RS13515	COG2304	oxidoreductase activity
FNB21_RS13520	COG0515	serine threonine protein kinase
FNB21_RS13525	COG0037	tRNA processing
FNB21_RS13530	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FNB21_RS13535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNB21_RS13540	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FNB21_RS13545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FNB21_RS13550	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNB21_RS13555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNB21_RS13560	COG0512	Glutamine amidotransferase of anthranilate synthase
FNB21_RS13565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNB21_RS13570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNB21_RS13575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNB21_RS13600	COG3880	PFAM UvrB UvrC protein
FNB21_RS13605	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FNB21_RS13610	COG0542	response to heat
FNB21_RS13615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FNB21_RS13620	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FNB21_RS13625	COG4956	integral membrane protein (PIN domain superfamily)
FNB21_RS13630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNB21_RS13640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNB21_RS13645	COG1045	serine acetyltransferase
FNB21_RS13650	COG0215	cysteine-tRNA ligase activity
FNB21_RS13660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNB21_RS13665	COG3688	RNA-binding protein containing a PIN domain
FNB21_RS13675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNB21_RS13680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNB21_RS13685	COG0250	Participates in transcription elongation, termination and antitermination
FNB21_RS13690	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNB21_RS13695	COG0081	regulation of translation
FNB21_RS13700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNB21_RS13705	COG0222	ribosome binding
FNB21_RS13710	COG2813	Specifically methylates the guanine in position
FNB21_RS13715	COG0085	RNA polymerase activity
FNB21_RS13725	COG1358	cellular component organization or biogenesis
FNB21_RS13730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNB21_RS13735	COG0049	tRNA binding
FNB21_RS13745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNB21_RS13750	COG0051	transcription antitermination factor activity, RNA binding
FNB21_RS13755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNB21_RS13760	COG0088	Forms part of the polypeptide exit tunnel
FNB21_RS13765	COG0089	rRNA binding
FNB21_RS13770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNB21_RS13775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNB21_RS13780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNB21_RS13790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNB21_RS13795	COG0255	Belongs to the universal ribosomal protein uL29 family
FNB21_RS13800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNB21_RS13805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNB21_RS13820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNB21_RS13835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNB21_RS13840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNB21_RS13845	COG1841	ribosomal large subunit assembly
FNB21_RS13855	COG0201	protein transport
FNB21_RS13860	COG0563	adenylate kinase activity
FNB21_RS13865	COG0024	Methionine aminopeptidase
FNB21_RS13870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNB21_RS13875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNB21_RS13880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNB21_RS13890	COG0202	RNA polymerase activity
FNB21_RS13895	COG0203	ribosomal protein L17
FNB21_RS13900	COG1122	ATPase activity
FNB21_RS13905	COG1122	ATPase activity
FNB21_RS13910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FNB21_RS13915	COG0101	tRNA pseudouridine synthase activity
FNB21_RS13920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNB21_RS13935	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNB21_RS13940	COG0489	protein tyrosine kinase activity
FNB21_RS13945	COG0583	DNA-binding transcription factor activity
FNB21_RS13955	COG2194	sulfuric ester hydrolase activity
FNB21_RS13960	COG0726	polysaccharide deacetylase
FNB21_RS14040	COG1595	DNA-templated transcription, initiation
FNB21_RS14045	COG5662	AntiSigma factor
FNB21_RS14050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FNB21_RS14060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNB21_RS14065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNB21_RS14080	COG3103	Sh3 type 3 domain protein
FNB21_RS14080	COG0791	NLP P60 protein
FNB21_RS14080	COG1388	LysM domain
FNB21_RS14085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNB21_RS14085	COG2213	PTS system mannitol-specific
FNB21_RS14090	COG3711	transcriptional antiterminator
FNB21_RS14095	COG0246	Mannitol dehydrogenase
FNB21_RS14105	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS14110	COG1970	mechanosensitive ion channel activity
FNB21_RS14135	COG1177	transmembrane transport
FNB21_RS14140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNB21_RS14150	COG0745	RESPONSE REGULATOR receiver
FNB21_RS14155	COG5002	protein histidine kinase activity
FNB21_RS14170	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FNB21_RS14170	COG3976	FMN-binding domain protein
FNB21_RS14175	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNB21_RS14180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNB21_RS14185	COG0513	Belongs to the DEAD box helicase family
FNB21_RS14190	COG4294	response to UV
FNB21_RS14195	COG0705	Rhomboid family
FNB21_RS14200	COG0736	holo-[acyl-carrier-protein] synthase activity
FNB21_RS14205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FNB21_RS14210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNB21_RS14215	COG0864	Transcriptional regulator
FNB21_RS14220	COG2337	Toxic component of a toxin-antitoxin (TA) module
FNB21_RS14225	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS14230	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS14235	COG2172	sigma factor antagonist activity
FNB21_RS14240	COG2208	phosphoserine phosphatase activity
FNB21_RS14245	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS14255	COG1191	sigma factor activity
FNB21_RS14260	COG2208	phosphoserine phosphatase activity
FNB21_RS14265	COG2183	response to ionizing radiation
FNB21_RS14360	COG0802	atpase or kinase
FNB21_RS14365	COG1214	PFAM Peptidase M22, glycoprotease
FNB21_RS14370	COG0456	acetyltransferase
FNB21_RS14380	COG0488	(ABC) transporter
FNB21_RS14385	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNB21_RS14390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNB21_RS14395	COG0805	protein transport
FNB21_RS14405	COG1266	CAAX protease self-immunity
FNB21_RS14410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNB21_RS14420	COG0714	Associated with various cellular activities
FNB21_RS14425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FNB21_RS14430	COG1305	Transglutaminase-like
FNB21_RS14435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNB21_RS14435	COG0519	Catalyzes the synthesis of GMP from XMP
FNB21_RS14440	COG2252	PERMEase
FNB21_RS14495	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FNB21_RS14500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FNB21_RS14505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNB21_RS14510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNB21_RS14515	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNB21_RS14520	COG0047	phosphoribosylformylglycinamidine synthase activity
FNB21_RS14525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNB21_RS14530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNB21_RS14535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNB21_RS14540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNB21_RS14545	COG0138	bifunctional purine biosynthesis protein purh
FNB21_RS14550	COG0151	Belongs to the GarS family
FNB21_RS14565	COG4496	protein, YerC YecD
FNB21_RS14570	COG0423	glycine-tRNA ligase activity
FNB21_RS14580	COG0210	DNA helicase
FNB21_RS14590	COG4851	CamS sex pheromone cAM373 precursor
FNB21_RS14600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNB21_RS14605	COG0154	amidase activity
FNB21_RS14615	COG1597	lipid kinase activity
FNB21_RS14625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS14635	COG0166	Belongs to the GPI family
FNB21_RS14640	COG1744	ABC transporter substrate-binding protein PnrA-like
FNB21_RS14645	COG3852	Histidine kinase
FNB21_RS14650	COG0024	Methionine aminopeptidase
FNB21_RS14655	COG2706	6-phosphogluconolactonase activity
FNB21_RS14665	COG4978	Transcriptional regulator
FNB21_RS14665	COG0789	Transcriptional regulator
FNB21_RS14670	COG2814	Major facilitator Superfamily
FNB21_RS14685	COG1126	abc transporter atp-binding protein
FNB21_RS14695	COG0765	amino acid transport
FNB21_RS14700	COG0765	amino acid transport
FNB21_RS14705	COG1113	amino acid transport
FNB21_RS14710	COG2733	membrane
FNB21_RS14715	COG3212	peptidase
FNB21_RS14720	COG3212	peptidase
FNB21_RS14725	COG5002	protein histidine kinase activity
FNB21_RS14725	COG3850	Histidine kinase
FNB21_RS14730	COG0745	RESPONSE REGULATOR receiver
FNB21_RS14735	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS14740	COG1764	response to oxidative stress
FNB21_RS14745	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FNB21_RS14755	COG2259	Doxx family
FNB21_RS14760	COG0693	protein deglycase activity
FNB21_RS14770	COG2318	DinB family
FNB21_RS14780	COG1115	amino acid carrier protein
FNB21_RS14795	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FNB21_RS14800	COG0598	Magnesium transport protein CorA
FNB21_RS14805	COG3290	protein histidine kinase activity
FNB21_RS14825	COG4191	Histidine kinase
FNB21_RS14830	COG0513	Belongs to the DEAD box helicase family
FNB21_RS14850	COG4842	Belongs to the WXG100 family
FNB21_RS14855	COG5417	Belongs to the EsaB family
FNB21_RS14860	COG4499	WXG100 protein secretion system (Wss), protein YukC
FNB21_RS14865	COG1674	ftsk spoiiie
FNB21_RS14865	COG0433	COG0433 Predicted ATPase
FNB21_RS14870	COG1511	domain protein
FNB21_RS14885	COG2356	endonuclease I
FNB21_RS14895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNB21_RS14910	COG0488	(ABC) transporter
FNB21_RS14915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNB21_RS14920	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FNB21_RS14930	COG1959	2 iron, 2 sulfur cluster binding
FNB21_RS14935	COG1017	nitric oxide dioxygenase activity
FNB21_RS14935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNB21_RS14945	COG0693	protein deglycase activity
FNB21_RS14950	COG2340	Cysteine-rich secretory protein family
FNB21_RS14955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FNB21_RS14960	COG4840	Belongs to the UPF0435 family
FNB21_RS14965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNB21_RS14970	COG4980	gas vesicle protein
FNB21_RS14975	COG1295	ribonuclease BN
FNB21_RS14980	COG2217	Heavy metal translocating P-type atpase
FNB21_RS14990	COG0640	Transcriptional regulator
FNB21_RS15000	COG0477	Major facilitator Superfamily
FNB21_RS15005	COG3479	Phenolic acid decarboxylase
FNB21_RS15015	COG3871	stress protein (general stress protein 26)
FNB21_RS15020	COG0387	Pfam Sodium calcium exchanger
FNB21_RS15030	COG0535	radical SAM domain protein
FNB21_RS15050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNB21_RS15060	COG1113	amino acid transport
FNB21_RS15065	COG5002	protein histidine kinase activity
FNB21_RS15085	COG1090	epimerase
FNB21_RS15095	COG4221	oxidoreductase activity
FNB21_RS15115	COG1988	membrane-bound metal-dependent
FNB21_RS15120	COG1194	a g-specific adenine glycosylase
FNB21_RS15130	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS15145	COG3557	Belongs to the UPF0374 family
FNB21_RS15150	COG1132	(ABC) transporter
FNB21_RS15155	COG4129	membrane
FNB21_RS15160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNB21_RS15165	COG4555	ABC transporter
FNB21_RS15185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNB21_RS15190	COG0735	belongs to the Fur family
FNB21_RS15300	COG4974	Belongs to the 'phage' integrase family
FNB21_RS15395	COG3382	B3 4 domain protein
FNB21_RS15410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNB21_RS15430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNB21_RS15445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNB21_RS15455	COG1968	undecaprenyl-diphosphatase activity
FNB21_RS15460	COG1301	dicarboxylic acid transport
FNB21_RS15465	COG0628	permease
FNB21_RS15470	COG0586	Pfam SNARE associated Golgi protein
FNB21_RS15475	COG2217	Heavy metal translocating P-type atpase
FNB21_RS15480	COG0531	amino acid
FNB21_RS15495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNB21_RS15500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FNB21_RS15505	COG3842	ATPase activity
FNB21_RS15510	COG1175	transmembrane transport
FNB21_RS15525	COG0584	glycerophosphoryl diester phosphodiesterase
FNB21_RS15540	COG4948	Mandelate Racemase Muconate Lactonizing
FNB21_RS15585	COG3584	3D domain protein
FNB21_RS15585	COG3583	domain protein
FNB21_RS15590	COG1876	peptidase activity
FNB21_RS15605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS15605	COG0456	acetyltransferase
FNB21_RS15610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNB21_RS15630	COG1609	Transcriptional regulator
FNB21_RS15635	COG2814	Major facilitator Superfamily
FNB21_RS15640	COG0673	inositol 2-dehydrogenase activity
FNB21_RS15665	COG1609	Transcriptional regulator
FNB21_RS15680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS15685	COG1522	sequence-specific DNA binding
FNB21_RS15705	COG2814	Major facilitator Superfamily
FNB21_RS15710	COG1309	transcriptional regulator
FNB21_RS15715	COG1187	pseudouridine synthase activity
FNB21_RS15725	COG1942	4-Oxalocrotonate Tautomerase
FNB21_RS15730	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNB21_RS15735	COG0747	negative chemotaxis
FNB21_RS15755	COG0084	hydrolase, TatD family'
FNB21_RS15760	COG2962	Rard protein
FNB21_RS15770	COG0628	permease
FNB21_RS15785	COG0604	alcohol dehydrogenase
FNB21_RS15790	COG1620	l-lactate permease
FNB21_RS15800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNB21_RS15810	COG0564	pseudouridine synthase activity
FNB21_RS15820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNB21_RS15825	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS15830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNB21_RS15830	COG3153	acetyltransferase
FNB21_RS15835	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FNB21_RS15840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNB21_RS15850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FNB21_RS15855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNB21_RS15860	COG1268	BioY protein
FNB21_RS15870	COG2719	SpoVR family
FNB21_RS15880	COG1959	2 iron, 2 sulfur cluster binding
FNB21_RS15885	COG0604	alcohol dehydrogenase
FNB21_RS15895	COG1126	abc transporter atp-binding protein
FNB21_RS15900	COG0765	amino acid transport
FNB21_RS15905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNB21_RS15915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNB21_RS15925	COG0352	thiamine-phosphate diphosphorylase activity
FNB21_RS15930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNB21_RS15945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FNB21_RS15950	COG0351	phosphomethylpyrimidine kinase
FNB21_RS15965	COG0702	epimerase
FNB21_RS15970	COG1253	flavin adenine dinucleotide binding
FNB21_RS15985	COG3842	ATPase activity
FNB21_RS15990	COG2508	Transcriptional regulator
FNB21_RS16005	COG0189	ligase activity
FNB21_RS16010	COG0189	ligase activity
FNB21_RS16020	COG3679	Belongs to the UPF0342 family
FNB21_RS16025	COG0561	phosphatase activity
FNB21_RS16030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNB21_RS16035	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS16040	COG1024	Enoyl-CoA hydratase
FNB21_RS16055	COG4152	abc transporter atp-binding protein
FNB21_RS16060	COG1668	transmembrane transport
FNB21_RS16080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNB21_RS16105	COG1846	Transcriptional regulator
FNB21_RS16120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNB21_RS16125	COG1695	Transcriptional regulator
FNB21_RS16130	COG2153	protein acetylation
FNB21_RS16135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNB21_RS16135	COG2755	lipolytic protein G-D-S-L family
FNB21_RS16140	COG0537	adenosine 5'-monophosphoramidase activity
FNB21_RS16145	COG1131	(ABC) transporter
FNB21_RS16150	COG4473	ABC transporter
FNB21_RS16160	COG1473	amidohydrolase
FNB21_RS16165	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS16170	COG3069	C4-dicarboxylate transmembrane transporter activity
FNB21_RS16175	COG2329	Antibiotic biosynthesis monooxygenase
FNB21_RS16180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNB21_RS16185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNB21_RS16190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNB21_RS16195	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FNB21_RS16205	COG0768	penicillin binding
FNB21_RS16230	COG1234	tRNA 3'-trailer cleavage
FNB21_RS16240	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS16245	COG1024	Enoyl-CoA hydratase
FNB21_RS16360	COG0501	Belongs to the peptidase M48B family
FNB21_RS16365	COG2224	Isocitrate lyase
FNB21_RS16375	COG4946	Tricorn protease homolog
FNB21_RS16375	COG0823	Involved in the tonB-independent uptake of proteins
FNB21_RS16375	COG1506	peptidase
FNB21_RS16380	COG0398	Pfam SNARE associated Golgi protein
FNB21_RS16385	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS16390	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FNB21_RS16395	COG1074	ATP-dependent DNA helicase activity
FNB21_RS16400	COG0420	3'-5' exonuclease activity
FNB21_RS16405	COG0419	ATPase involved in DNA repair
FNB21_RS16410	COG1403	HNH endonuclease
FNB21_RS16445	COG2311	Membrane
FNB21_RS16460	COG0367	asparagine synthase
FNB21_RS16475	COG1562	ergosterol biosynthetic process
FNB21_RS16485	COG0366	Alpha amylase catalytic
FNB21_RS16485	COG1874	Beta-galactosidase
FNB21_RS16490	COG1609	Transcriptional regulator
FNB21_RS16495	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS16500	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNB21_RS16505	COG4187	Peptidase family M20/M25/M40
FNB21_RS16510	COG0833	amino acid
FNB21_RS16515	COG3829	transcription factor binding
FNB21_RS16520	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS16525	COG1666	GTP binding
FNB21_RS16530	COG2996	Protein conserved in bacteria
FNB21_RS16540	COG1307	EDD domain protein, DegV family
FNB21_RS16545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS16555	COG0561	phosphatase activity
FNB21_RS16560	COG2151	metal-sulfur cluster biosynthetic enzyme
FNB21_RS16565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNB21_RS16570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNB21_RS16575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNB21_RS16580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNB21_RS16600	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNB21_RS16615	COG0542	response to heat
FNB21_RS16630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNB21_RS16635	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FNB21_RS16640	COG2084	Dehydrogenase
FNB21_RS16650	COG2267	carboxylic ester hydrolase activity
FNB21_RS16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNB21_RS16675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNB21_RS16680	COG5504	Zn-dependent protease
FNB21_RS16685	COG0444	Belongs to the ABC transporter superfamily
FNB21_RS16690	COG4608	Belongs to the ABC transporter superfamily
FNB21_RS16700	COG0601	transmembrane transport
FNB21_RS16715	COG0180	Tryptophanyl-tRNA synthetase
FNB21_RS16730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNB21_RS16735	COG0444	Belongs to the ABC transporter superfamily
FNB21_RS16740	COG4608	Belongs to the ABC transporter superfamily
FNB21_RS16745	COG0456	acetyltransferase
FNB21_RS16750	COG1113	amino acid transport
FNB21_RS16755	COG0531	amino acid
FNB21_RS16760	COG1393	Belongs to the ArsC family
FNB21_RS16765	COG0583	DNA-binding transcription factor activity
FNB21_RS16780	COG0861	Integral membrane protein TerC family
FNB21_RS16790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNB21_RS16800	COG1164	Oligoendopeptidase f
FNB21_RS16810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNB21_RS16815	COG2346	COG2346, Truncated hemoglobins
FNB21_RS16820	COG0741	lytic transglycosylase activity
FNB21_RS16825	COG4116	CYTH
FNB21_RS16835	COG2357	RelA SpoT domain protein
FNB21_RS16845	COG0564	pseudouridine synthase activity
FNB21_RS16855	COG2239	Acts as a magnesium transporter
FNB21_RS16860	COG0569	domain protein
FNB21_RS16860	COG0475	glutathione-regulated potassium exporter activity
FNB21_RS16910	COG0210	DNA helicase
FNB21_RS16920	COG2323	membrane
FNB21_RS16925	COG2153	protein acetylation
FNB21_RS16935	COG2382	esterase
FNB21_RS16945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FNB21_RS16955	COG1737	Transcriptional regulator
FNB21_RS16960	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNB21_RS16965	COG1070	Carbohydrate kinase
FNB21_RS16970	COG1953	Uracil, thiamine, allantoin
FNB21_RS16990	COG1522	sequence-specific DNA binding
FNB21_RS17000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNB21_RS17015	COG3142	Participates in the control of copper homeostasis
FNB21_RS17020	COG1113	amino acid transport
FNB21_RS17030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS17035	COG1309	transcriptional regulator
FNB21_RS17040	COG3711	transcriptional antiterminator
FNB21_RS17040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNB21_RS17045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FNB21_RS17050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FNB21_RS17055	COG1447	Phosphotransferase system cellobiose-specific component IIA
FNB21_RS17060	COG1486	melibiose metabolic process
FNB21_RS17070	COG3279	Response regulator of the LytR AlgR family
FNB21_RS17080	COG1346	cytolysis
FNB21_RS17090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNB21_RS17095	COG0243	molybdopterin cofactor binding
FNB21_RS17100	COG2223	nitrite transmembrane transporter activity
FNB21_RS17105	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNB21_RS17120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNB21_RS17130	COG0028	Belongs to the TPP enzyme family
FNB21_RS17130	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FNB21_RS17135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNB21_RS17135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNB21_RS17145	COG3527	Alpha-acetolactate decarboxylase
FNB21_RS17150	COG0028	Belongs to the TPP enzyme family
FNB21_RS17160	COG4895	conserved protein (DUF2196)
FNB21_RS17170	COG1733	regulation of RNA biosynthetic process
FNB21_RS17175	COG2814	Major facilitator Superfamily
FNB21_RS17180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS17205	COG3052	prosthetic group binding
FNB21_RS17220	COG0784	Response regulator, receiver
FNB21_RS17225	COG4191	Histidine kinase
FNB21_RS17230	COG2066	Belongs to the glutaminase family
FNB21_RS17235	COG1115	amino acid carrier protein
FNB21_RS17240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNB21_RS17255	COG0531	amino acid
FNB21_RS17265	COG1607	acyl-coa hydrolase
FNB21_RS17275	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FNB21_RS17290	COG0390	transport system, permease component
FNB21_RS17295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNB21_RS17310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNB21_RS17315	COG1136	(ABC) transporter
FNB21_RS17320	COG0577	efflux transmembrane transporter activity
FNB21_RS17330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNB21_RS17350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNB21_RS17355	COG0833	amino acid
FNB21_RS17365	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FNB21_RS17370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNB21_RS17380	COG0861	Integral membrane protein TerC family
FNB21_RS17385	COG1301	dicarboxylic acid transport
FNB21_RS17390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNB21_RS17395	COG3290	protein histidine kinase activity
FNB21_RS17435	COG1476	TRANSCRIPTIONal
FNB21_RS17445	COG1368	sulfuric ester hydrolase activity
FNB21_RS17460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS17465	COG2040	homocysteine
FNB21_RS17475	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNB21_RS17490	COG2851	Citrate transporter
FNB21_RS17495	COG3290	protein histidine kinase activity
FNB21_RS17500	COG4565	transcriptional regulatory protein
FNB21_RS17505	COG3181	Tripartite tricarboxylate transporter family receptor
FNB21_RS17515	COG0583	DNA-binding transcription factor activity
FNB21_RS17520	COG3180	Ammonia monooxygenase
FNB21_RS17525	COG2226	methyltransferase
FNB21_RS17540	COG2113	Glycine betaine
FNB21_RS17545	COG1309	transcriptional regulator
FNB21_RS17550	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS17565	COG0531	amino acid
FNB21_RS17570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNB21_RS17575	COG1464	Belongs to the NlpA lipoprotein family
FNB21_RS17580	COG2011	ABC-type metal ion transport system permease component
FNB21_RS17585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNB21_RS17600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS17610	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FNB21_RS17615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS17620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS17645	COG1737	Transcriptional regulator
FNB21_RS17650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS17650	COG1263	PTS System
FNB21_RS17660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNB21_RS17665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FNB21_RS17670	COG1116	anion transmembrane transporter activity
FNB21_RS17675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNB21_RS17680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNB21_RS17690	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNB21_RS17695	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FNB21_RS17700	COG1733	regulation of RNA biosynthetic process
FNB21_RS17735	COG1511	domain protein
FNB21_RS17745	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FNB21_RS17750	COG1733	regulation of RNA biosynthetic process
FNB21_RS17755	COG4221	oxidoreductase activity
FNB21_RS17755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FNB21_RS17755	COG3321	synthase
FNB21_RS17755	COG0604	alcohol dehydrogenase
FNB21_RS17765	COG1132	(ABC) transporter
FNB21_RS17770	COG1132	(ABC) transporter
FNB21_RS17780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNB21_RS17785	COG3162	membrane
FNB21_RS17795	COG1414	Transcriptional regulator
FNB21_RS17800	COG0656	L-ascorbic acid biosynthetic process
FNB21_RS17805	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FNB21_RS17810	COG1846	Transcriptional regulator
FNB21_RS17815	COG1566	PFAM secretion protein HlyD family protein
FNB21_RS17820	COG2814	Major facilitator Superfamily
FNB21_RS17825	COG0655	NAD(P)H dehydrogenase (quinone) activity
FNB21_RS17840	COG1609	Transcriptional regulator
FNB21_RS17845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNB21_RS17855	COG1129	ABC transporter
FNB21_RS17860	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNB21_RS17865	COG1879	ABC-type sugar transport system periplasmic component
FNB21_RS17870	COG3584	3D domain protein
FNB21_RS17870	COG3583	domain protein
FNB21_RS17880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNB21_RS17930	COG0745	RESPONSE REGULATOR receiver
FNB21_RS17935	COG5002	protein histidine kinase activity
FNB21_RS17945	COG2267	carboxylic ester hydrolase activity
FNB21_RS17955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNB21_RS17970	COG0402	S-adenosylhomocysteine deaminase activity
FNB21_RS17975	COG2252	PERMEase
FNB21_RS17980	COG1609	Transcriptional regulator
FNB21_RS17985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNB21_RS17990	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS18000	COG0710	3-dehydroquinate dehydratase activity
FNB21_RS18010	COG1263	PTS System
FNB21_RS18010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS18015	COG0366	Alpha amylase catalytic
FNB21_RS18020	COG2188	Transcriptional regulator
FNB21_RS18025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNB21_RS18030	COG1984	allophanate hydrolase subunit 2
FNB21_RS18035	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNB21_RS18040	COG1914	H( )-stimulated, divalent metal cation uptake system
FNB21_RS18045	COG1272	protein, Hemolysin III
FNB21_RS18060	COG0778	Nitroreductase
FNB21_RS18065	COG0628	permease
FNB21_RS18095	COG2271	Major facilitator Superfamily
FNB21_RS18100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNB21_RS18105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNB21_RS18110	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS18125	COG0439	Biotin carboxylase
FNB21_RS18140	COG0531	amino acid
FNB21_RS18145	COG0402	S-adenosylhomocysteine deaminase activity
FNB21_RS18150	COG1278	Cold shock
FNB21_RS18155	COG2910	NAD(P)H-binding
FNB21_RS18160	COG0673	inositol 2-dehydrogenase activity
FNB21_RS18165	COG0450	alkyl hydroperoxide reductase
FNB21_RS18170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS18195	COG4251	negative regulation of phosphorylation
FNB21_RS18195	COG2203	Gaf domain
FNB21_RS18195	COG3706	GGDEF domain
FNB21_RS18195	COG5001	Diguanylate cyclase
FNB21_RS18200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNB21_RS18280	COG1649	PFAM Uncharacterised BCR, COG1649
FNB21_RS18285	COG1737	Transcriptional regulator
FNB21_RS18305	COG1486	melibiose metabolic process
FNB21_RS18315	COG1447	Phosphotransferase system cellobiose-specific component IIA
FNB21_RS18325	COG2971	BadF BadG BcrA BcrD
FNB21_RS18330	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNB21_RS18335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNB21_RS18345	COG3037	sugar-specific permease SgaT UlaA
FNB21_RS18360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNB21_RS18375	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS18380	COG4106	trans-aconitate 2-methyltransferase activity
FNB21_RS18385	COG0583	DNA-binding transcription factor activity
FNB21_RS18400	COG0667	Aldo Keto reductase
FNB21_RS18415	COG0154	amidase activity
FNB21_RS18425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FNB21_RS18460	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FNB21_RS18470	COG1733	regulation of RNA biosynthetic process
FNB21_RS18485	COG0385	Bile acid
FNB21_RS18495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNB21_RS18500	COG4191	Histidine kinase
FNB21_RS18505	COG0784	Response regulator, receiver
FNB21_RS18520	COG0791	NLP P60 protein
FNB21_RS18520	COG1388	LysM domain
FNB21_RS18530	COG2385	sporulation resulting in formation of a cellular spore
FNB21_RS18535	COG0656	L-ascorbic acid biosynthetic process
FNB21_RS18550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNB21_RS18555	COG4948	Mandelate Racemase Muconate Lactonizing
FNB21_RS18575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNB21_RS18590	COG0477	Major facilitator Superfamily
FNB21_RS18595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNB21_RS18605	COG0640	Transcriptional regulator
FNB21_RS18610	COG5658	integral membrane protein
FNB21_RS18630	COG5001	Diguanylate cyclase
FNB21_RS18630	COG3300	MHYT domain
FNB21_RS18635	COG0302	gtp cyclohydrolase
FNB21_RS18655	COG0531	amino acid
FNB21_RS18675	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FNB21_RS18710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FNB21_RS18720	COG1396	sequence-specific DNA binding
FNB21_RS18740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNB21_RS18760	COG1215	transferase activity, transferring glycosyl groups
FNB21_RS18775	COG2385	sporulation resulting in formation of a cellular spore
FNB21_RS18775	COG2247	cell wall binding repeat
FNB21_RS18790	COG4464	protein tyrosine phosphatase activity
FNB21_RS18795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNB21_RS18800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNB21_RS18805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNB21_RS18810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNB21_RS18815	COG0438	transferase activity, transferring glycosyl groups
FNB21_RS18840	COG0110	maltose O-acetyltransferase activity
FNB21_RS18850	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FNB21_RS18865	COG1482	cell wall glycoprotein biosynthetic process
FNB21_RS18870	COG3944	biosynthesis protein
FNB21_RS18875	COG0489	protein tyrosine kinase activity
FNB21_RS18880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNB21_RS18895	COG1215	transferase activity, transferring glycosyl groups
FNB21_RS18895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNB21_RS18915	COG1682	transport, permease protein
FNB21_RS18920	COG1134	teichoic acid transport
FNB21_RS18925	COG1316	TRANSCRIPTIONal
FNB21_RS18945	COG0028	Belongs to the TPP enzyme family
FNB21_RS18950	COG0069	glutamate synthase activity
FNB21_RS18960	COG2084	Dehydrogenase
FNB21_RS18990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNB21_RS18995	COG2146	nitrite reductase [NAD(P)H] activity
FNB21_RS19005	COG2116	formate transmembrane transporter activity
FNB21_RS19015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNB21_RS19020	COG4975	Glucose uptake
FNB21_RS19035	COG0534	Mate efflux family protein
FNB21_RS19045	COG1316	TRANSCRIPTIONal
FNB21_RS19055	COG0598	Magnesium transport protein CorA
FNB21_RS19060	COG1404	Belongs to the peptidase S8 family
FNB21_RS19080	COG4821	SIS domain
FNB21_RS19085	COG2188	Transcriptional regulator
FNB21_RS19090	COG0363	glucosamine-6-phosphate deaminase activity
FNB21_RS19095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNB21_RS19100	COG1263	PTS System
FNB21_RS19100	COG2190	(PTS) system
FNB21_RS19100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS19105	COG1811	Na channel or pump
FNB21_RS19145	COG1131	(ABC) transporter
FNB21_RS19150	COG1253	flavin adenine dinucleotide binding
FNB21_RS19155	COG0789	Transcriptional regulator
FNB21_RS19165	COG0346	lactoylglutathione lyase activity
FNB21_RS19170	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FNB21_RS19170	COG2105	PFAM AIG2 family protein
FNB21_RS19215	COG0456	acetyltransferase
FNB21_RS19220	COG1473	amidohydrolase
FNB21_RS19230	COG4187	Peptidase family M20/M25/M40
FNB21_RS19245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FNB21_RS19245	COG0456	acetyltransferase
FNB21_RS19265	COG2252	PERMEase
FNB21_RS19275	COG3279	Response regulator of the LytR AlgR family
FNB21_RS19280	COG4555	ABC transporter
FNB21_RS19290	COG0789	Transcriptional regulator
FNB21_RS19295	COG1846	Transcriptional regulator
FNB21_RS19300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNB21_RS19300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNB21_RS19320	COG1785	Belongs to the alkaline phosphatase family
FNB21_RS19330	COG2205	protein histidine kinase activity
FNB21_RS19330	COG0784	Response regulator, receiver
FNB21_RS19335	COG0861	Integral membrane protein TerC family
FNB21_RS19340	COG1191	sigma factor activity
FNB21_RS19370	COG3243	poly(R)-hydroxyalkanoic acid synthase
FNB21_RS19375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNB21_RS19385	COG2186	Transcriptional regulator
FNB21_RS19390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FNB21_RS19400	COG0247	lactate metabolic process
FNB21_RS19405	COG1139	Iron-sulfur cluster binding protein
FNB21_RS19410	COG1556	Lactate utilization protein
FNB21_RS19415	COG5002	protein histidine kinase activity
FNB21_RS19420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNB21_RS19425	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FNB21_RS19430	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FNB21_RS19435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNB21_RS19440	COG0436	Aminotransferase
FNB21_RS19445	COG1850	ribulose-bisphosphate carboxylase activity
FNB21_RS19450	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FNB21_RS19455	COG0235	Class ii aldolase
FNB21_RS19460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FNB21_RS19470	COG1129	ABC transporter
FNB21_RS19475	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNB21_RS19505	COG1846	Transcriptional regulator
FNB21_RS19515	COG4191	Histidine kinase
FNB21_RS19525	COG0542	response to heat
FNB21_RS19530	COG1757	Na H antiporter
FNB21_RS19540	COG0300	oxidoreductase activity
FNB21_RS19545	COG0697	spore germination
FNB21_RS19565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FNB21_RS19570	COG0720	synthase
FNB21_RS19580	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FNB21_RS19585	COG0702	epimerase
FNB21_RS19595	COG4873	Protein conserved in bacteria
FNB21_RS19615	COG3773	Cell wall hydrolase
FNB21_RS19655	COG1410	methionine synthase
FNB21_RS19655	COG0646	methionine synthase
FNB21_RS19660	COG0646	methionine synthase
FNB21_RS19660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FNB21_RS19665	COG3949	Membrane
FNB21_RS19675	COG0307	riboflavin synthase, alpha
FNB21_RS19685	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNB21_RS19695	COG3711	transcriptional antiterminator
FNB21_RS19700	COG2190	(PTS) system
FNB21_RS19700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS19700	COG1263	PTS System
FNB21_RS19715	COG1346	cytolysis
FNB21_RS19725	COG0583	DNA-binding transcription factor activity
FNB21_RS19735	COG0456	acetyltransferase
FNB21_RS19740	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS19745	COG0778	Nitroreductase
FNB21_RS19770	COG0784	Response regulator, receiver
FNB21_RS19770	COG0835	chemotaxis
FNB21_RS19785	COG0248	Ppx GppA phosphatase
FNB21_RS19800	COG1408	metallophosphoesterase
FNB21_RS19805	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS19810	COG2200	EAL domain
FNB21_RS19825	COG4703	Protein of unknown function (DUF1797)
FNB21_RS19830	COG0517	IMP dehydrogenase activity
FNB21_RS19835	COG0583	DNA-binding transcription factor activity
FNB21_RS19840	COG2171	N-acyltransferase activity
FNB21_RS19845	COG1473	amidohydrolase
FNB21_RS19855	COG0668	transmembrane transport
FNB21_RS19860	COG0450	alkyl hydroperoxide reductase
FNB21_RS19865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS19870	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FNB21_RS19880	COG1132	(ABC) transporter
FNB21_RS19885	COG1132	(ABC) transporter
FNB21_RS19890	COG0569	domain protein
FNB21_RS19895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNB21_RS19900	COG5503	Protein of unknown function (DUF1447)
FNB21_RS19905	COG0561	phosphatase activity
FNB21_RS19930	COG0022	dehydrogenase e1 component
FNB21_RS19935	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNB21_RS19965	COG4476	Belongs to the UPF0223 family
FNB21_RS19970	COG4493	Belongs to the UPF0637 family
FNB21_RS19980	COG0483	inositol monophosphate 1-phosphatase activity
FNB21_RS19990	COG1217	gtp-binding protein TYPA
FNB21_RS20005	COG4896	Protein conserved in bacteria
FNB21_RS20020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNB21_RS20025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNB21_RS20030	COG4838	Belongs to the UPF0358 family
FNB21_RS20035	COG0772	Belongs to the SEDS family
FNB21_RS20045	COG1612	heme a metabolic process
FNB21_RS20050	COG0109	protoheme IX farnesyltransferase activity
FNB21_RS20085	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FNB21_RS20090	COG2340	Cysteine-rich secretory protein family
FNB21_RS20100	COG2738	Putative neutral zinc metallopeptidase
FNB21_RS20105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS20110	COG1694	Mazg nucleotide pyrophosphohydrolase
FNB21_RS20115	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNB21_RS20120	COG1803	Methylglyoxal synthase
FNB21_RS20125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNB21_RS20130	COG0438	transferase activity, transferring glycosyl groups
FNB21_RS20135	COG0617	tRNA 3'-terminal CCA addition
FNB21_RS20140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FNB21_RS20140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FNB21_RS20150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNB21_RS20155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNB21_RS20160	COG1199	ATP-dependent helicase activity
FNB21_RS20160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNB21_RS20180	COG0436	Aminotransferase
FNB21_RS20185	COG0017	Asparaginyl-tRNA synthetase
FNB21_RS20190	COG3935	DnaD domain protein
FNB21_RS20195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNB21_RS20205	COG4499	WXG100 protein secretion system (Wss), protein YukC
FNB21_RS20205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNB21_RS20210	COG3331	DNA recombination
FNB21_RS20245	COG5337	Spore coat protein CotH
FNB21_RS20260	COG0626	cystathionine gamma-synthase activity
FNB21_RS20265	COG0626	cystathionine gamma-synthase activity
FNB21_RS20280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNB21_RS20300	COG3706	GGDEF domain
FNB21_RS20310	COG1205	dead DEAH box helicase
FNB21_RS20310	COG1111	helicase
FNB21_RS20315	COG3359	exonuclease
FNB21_RS20325	COG4474	Belongs to the UPF0398 family
FNB21_RS20330	COG3599	regulation of cell shape
FNB21_RS20360	COG2197	response regulator
FNB21_RS20365	COG0366	Alpha amylase catalytic
FNB21_RS20370	COG0116	Belongs to the methyltransferase superfamily
FNB21_RS20385	COG1175	transmembrane transport
FNB21_RS20395	COG3842	ATPase activity
FNB21_RS20405	COG1199	ATP-dependent helicase activity
FNB21_RS20410	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FNB21_RS20420	COG2233	PERMEase
FNB21_RS20425	COG0583	DNA-binding transcription factor activity
FNB21_RS20430	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS20440	COG3424	synthase
FNB21_RS20445	COG1755	Isoprenylcysteine carboxyl methyltransferase
FNB21_RS20450	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FNB21_RS20455	COG3541	Predicted nucleotidyltransferase
FNB21_RS20480	COG0328	RNA-DNA hybrid ribonuclease activity
FNB21_RS20485	COG0328	RNA-DNA hybrid ribonuclease activity
FNB21_RS20510	COG2814	Major facilitator Superfamily
FNB21_RS20520	COG2233	PERMEase
FNB21_RS20525	COG2362	D-Aminopeptidase
FNB21_RS20530	COG0601	transmembrane transport
FNB21_RS20535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNB21_RS20540	COG0444	Belongs to the ABC transporter superfamily
FNB21_RS20545	COG4166	transmembrane transport
FNB21_RS20550	COG1619	proteins homologs of microcin C7 resistance protein MccF
FNB21_RS20555	COG0791	NLP P60 protein
FNB21_RS20560	COG4608	Belongs to the ABC transporter superfamily
FNB21_RS20580	COG3300	MHYT domain
FNB21_RS20580	COG5001	Diguanylate cyclase
FNB21_RS20610	COG2197	response regulator
FNB21_RS20615	COG4585	Histidine kinase
FNB21_RS20620	COG3239	Fatty acid desaturase
FNB21_RS20625	COG2205	protein histidine kinase activity
FNB21_RS20635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNB21_RS20650	COG0791	NLP P60 protein
FNB21_RS20650	COG1388	LysM domain
FNB21_RS20655	COG1819	glycosyl
FNB21_RS20660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNB21_RS20675	COG2814	Major facilitator Superfamily
FNB21_RS20685	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS20690	COG3964	amidohydrolase
FNB21_RS20710	COG2188	Transcriptional regulator
FNB21_RS20720	COG0434	BtpA family
FNB21_RS20725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNB21_RS20735	COG1785	Belongs to the alkaline phosphatase family
FNB21_RS20740	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNB21_RS20745	COG1404	Belongs to the peptidase S8 family
FNB21_RS20755	COG1846	Transcriptional regulator
FNB21_RS20760	COG1566	PFAM secretion protein HlyD family protein
FNB21_RS20765	COG2814	Major facilitator Superfamily
FNB21_RS20770	COG1846	Transcriptional regulator
FNB21_RS20790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS20795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS20800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNB21_RS20805	COG1120	ATPase activity
FNB21_RS20810	COG0492	ferredoxin-NADP+ reductase activity
FNB21_RS20820	COG2814	Major facilitator Superfamily
FNB21_RS20840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNB21_RS20845	COG1733	regulation of RNA biosynthetic process
FNB21_RS20860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNB21_RS20870	COG3448	diguanylate cyclase activity
FNB21_RS20870	COG4175	Glycine betaine
FNB21_RS20875	COG4176	ABC-type proline glycine betaine transport system permease component
FNB21_RS20885	COG2205	protein histidine kinase activity
FNB21_RS20885	COG0784	Response regulator, receiver
FNB21_RS20890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FNB21_RS20895	COG2208	phosphoserine phosphatase activity
FNB21_RS20905	COG0531	amino acid
FNB21_RS20915	COG1011	Hydrolase
FNB21_RS20920	COG0405	Gamma-glutamyltransferase
FNB21_RS20930	COG1621	beta-fructofuranosidase activity
FNB21_RS20935	COG2193	ferroxidase activity
FNB21_RS20940	COG0477	Major facilitator Superfamily
FNB21_RS20945	COG0156	8-amino-7-oxononanoate synthase activity
FNB21_RS20950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNB21_RS20960	COG2814	Major facilitator Superfamily
FNB21_RS20975	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS20990	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS20995	COG1113	amino acid transport
FNB21_RS21005	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FNB21_RS21025	COG1113	amino acid transport
FNB21_RS21045	COG1609	Transcriptional regulator
FNB21_RS21060	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FNB21_RS21065	COG1621	beta-fructofuranosidase activity
FNB21_RS21070	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FNB21_RS21070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FNB21_RS21075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNB21_RS21080	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNB21_RS21085	COG3715	PTS system
FNB21_RS21090	COG3716	PTS system mannose fructose sorbose family IID component
FNB21_RS21095	COG1621	beta-fructofuranosidase activity
FNB21_RS21100	COG0765	amino acid transport
FNB21_RS21105	COG0765	amino acid transport
FNB21_RS21110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNB21_RS21115	COG1464	Belongs to the NlpA lipoprotein family
FNB21_RS21120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNB21_RS21125	COG2011	ABC-type metal ion transport system permease component
FNB21_RS21145	COG1464	Belongs to the NlpA lipoprotein family
FNB21_RS21150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNB21_RS21155	COG2011	ABC-type metal ion transport system permease component
FNB21_RS21160	COG1464	Belongs to the NlpA lipoprotein family
FNB21_RS21165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS21170	COG0024	Methionine aminopeptidase
FNB21_RS21190	COG0596	Alpha beta hydrolase
FNB21_RS21195	COG0697	spore germination
FNB21_RS21210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNB21_RS21215	COG0531	amino acid
FNB21_RS21230	COG2723	6-phospho-beta-galactosidase activity
FNB21_RS21235	COG2188	Transcriptional regulator
FNB21_RS21245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNB21_RS21255	COG0656	L-ascorbic acid biosynthetic process
FNB21_RS21260	COG2986	histidine ammonia-lyase
FNB21_RS21270	COG1228	amidohydrolase
FNB21_RS21275	COG0010	Belongs to the arginase family
FNB21_RS21290	COG0473	3-isopropylmalate dehydrogenase activity
FNB21_RS21295	COG1288	antiporter activity
FNB21_RS21300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNB21_RS21345	COG2364	Membrane
FNB21_RS21350	COG1846	Transcriptional regulator
FNB21_RS21355	COG0456	acetyltransferase
FNB21_RS21360	COG0640	Transcriptional regulator
FNB21_RS21425	COG0574	Belongs to the PEP-utilizing enzyme family
FNB21_RS21425	COG3848	Pyruvate phosphate dikinase
FNB21_RS21430	COG1309	transcriptional regulator
FNB21_RS21440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FNB21_RS21445	COG3958	Transketolase
FNB21_RS21450	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS21455	COG2186	Transcriptional regulator
FNB21_RS21465	COG0205	6-phosphofructokinase activity
FNB21_RS21475	COG0698	ribose 5-phosphate isomerase
FNB21_RS21500	COG0791	NLP P60 protein
FNB21_RS21500	COG1388	LysM domain
FNB21_RS21505	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FNB21_RS21520	COG2318	DinB family
FNB21_RS21545	COG0583	DNA-binding transcription factor activity
FNB21_RS21550	COG0596	Alpha beta hydrolase
FNB21_RS21580	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS21595	COG5002	protein histidine kinase activity
FNB21_RS21595	COG3850	Histidine kinase
FNB21_RS21600	COG0745	RESPONSE REGULATOR receiver
FNB21_RS21625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FNB21_RS21635	COG0697	spore germination
FNB21_RS21665	COG0387	Pfam Sodium calcium exchanger
FNB21_RS21670	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS21685	COG1309	transcriptional regulator
FNB21_RS21690	COG0861	Integral membrane protein TerC family
FNB21_RS21700	COG5577	PFAM Coat F domain
FNB21_RS21710	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS21720	COG1522	sequence-specific DNA binding
FNB21_RS21725	COG3813	Protein conserved in bacteria
FNB21_RS21745	COG2076	Multidrug Resistance protein
FNB21_RS21770	COG1278	Cold shock
FNB21_RS21780	COG0513	Belongs to the DEAD box helicase family
FNB21_RS21785	COG1278	Cold shock
FNB21_RS21800	COG0028	Belongs to the TPP enzyme family
FNB21_RS21835	COG2172	sigma factor antagonist activity
FNB21_RS21845	COG1376	ErfK ybiS ycfS ynhG family protein
FNB21_RS21850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNB21_RS21875	COG2226	methyltransferase
FNB21_RS21885	COG1733	regulation of RNA biosynthetic process
FNB21_RS21890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS21905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS21910	COG3420	alginic acid biosynthetic process
FNB21_RS21930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNB21_RS21935	COG0640	Transcriptional regulator
FNB21_RS21945	COG0346	lactoylglutathione lyase activity
FNB21_RS21950	COG0475	glutathione-regulated potassium exporter activity
FNB21_RS21950	COG0589	response to stress
FNB21_RS21960	COG2076	Multidrug Resistance protein
FNB21_RS21965	COG2076	Multidrug Resistance protein
FNB21_RS21995	COG0488	(ABC) transporter
FNB21_RS22020	COG0583	DNA-binding transcription factor activity
FNB21_RS22025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FNB21_RS22035	COG0753	catalase activity
FNB21_RS22050	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS22055	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS22075	COG0384	phenazine biosynthesis protein PhzF
FNB21_RS22085	COG5577	PFAM Coat F domain
FNB21_RS22095	COG1063	alcohol dehydrogenase
FNB21_RS22100	COG5577	PFAM Coat F domain
FNB21_RS22120	COG0784	Response regulator, receiver
FNB21_RS22120	COG2205	protein histidine kinase activity
FNB21_RS22140	COG0673	inositol 2-dehydrogenase activity
FNB21_RS22150	COG1082	Xylose isomerase domain protein TIM barrel
FNB21_RS22155	COG2814	Major facilitator Superfamily
FNB21_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS22190	COG0789	Transcriptional regulator
FNB21_RS22195	COG1278	Cold shock
FNB21_RS22245	COG1113	amino acid transport
FNB21_RS22255	COG2207	Transcriptional regulator
FNB21_RS22265	COG2376	Dihydroxyacetone kinase
FNB21_RS22285	COG0745	RESPONSE REGULATOR receiver
FNB21_RS22290	COG0745	RESPONSE REGULATOR receiver
FNB21_RS22295	COG5002	protein histidine kinase activity
FNB21_RS22300	COG0671	phosphoesterase, PA-phosphatase related
FNB21_RS22360	COG2318	DinB family
FNB21_RS22365	COG2890	protein-(glutamine-N5) methyltransferase activity
FNB21_RS22405	COG2311	Membrane
FNB21_RS22435	COG1114	Component of the transport system for branched-chain amino acids
FNB21_RS22445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNB21_RS22455	COG4282	regulation of fungal-type cell wall biogenesis
FNB21_RS22485	COG0574	Belongs to the PEP-utilizing enzyme family
FNB21_RS22485	COG3848	Pyruvate phosphate dikinase
FNB21_RS22490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNB21_RS22500	COG0601	transmembrane transport
FNB21_RS22505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNB21_RS22510	COG0444	Belongs to the ABC transporter superfamily
FNB21_RS22515	COG4608	Belongs to the ABC transporter superfamily
FNB21_RS22520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNB21_RS22525	COG0477	Major facilitator Superfamily
FNB21_RS22545	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS22580	COG0517	IMP dehydrogenase activity
FNB21_RS22600	COG1309	transcriptional regulator
FNB21_RS22615	COG1070	Carbohydrate kinase
FNB21_RS22620	COG0477	Major facilitator Superfamily
FNB21_RS22620	COG2814	Major facilitator Superfamily
FNB21_RS22630	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNB21_RS22635	COG1845	cytochrome c oxidase, subunit III
FNB21_RS22645	COG0589	response to stress
FNB21_RS22655	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS22660	COG1612	heme a metabolic process
FNB21_RS22665	COG2072	flavoprotein involved in K transport
FNB21_RS22675	COG2252	PERMEase
FNB21_RS22685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNB21_RS22695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNB21_RS22700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNB21_RS22705	COG3284	Transcriptional regulator
FNB21_RS22720	COG1846	Transcriptional regulator
FNB21_RS22745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNB21_RS22775	COG0589	response to stress
FNB21_RS22780	COG5002	protein histidine kinase activity
FNB21_RS22790	COG1937	Protein conserved in bacteria
FNB21_RS22795	COG2608	mercury ion transmembrane transporter activity
FNB21_RS22800	COG2217	Heavy metal translocating P-type atpase
FNB21_RS22810	COG1388	LysM domain
FNB21_RS22815	COG2271	Major facilitator Superfamily
FNB21_RS22845	COG0640	Transcriptional regulator
FNB21_RS22850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FNB21_RS22855	COG0551	DNA topoisomerase type I activity
FNB21_RS22855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNB21_RS22860	COG5444	nuclease activity
FNB21_RS22880	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FNB21_RS22885	COG2323	membrane
FNB21_RS22900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNB21_RS22910	COG0473	3-isopropylmalate dehydrogenase activity
FNB21_RS22915	COG2814	Major facilitator Superfamily
FNB21_RS22920	COG1733	regulation of RNA biosynthetic process
FNB21_RS22925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNB21_RS22925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNB21_RS22930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNB21_RS22930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNB21_RS22955	COG5566	PFAM Mor transcription activator
FNB21_RS22970	COG0561	phosphatase activity
FNB21_RS22975	COG1876	peptidase activity
FNB21_RS23020	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FNB21_RS23035	COG0386	Belongs to the glutathione peroxidase family
FNB21_RS23040	COG1418	mRNA catabolic process
FNB21_RS23045	COG0488	(ABC) transporter
FNB21_RS23050	COG1413	lyase activity
FNB21_RS23055	COG0726	polysaccharide deacetylase
FNB21_RS23065	COG2521	methyltransferase
FNB21_RS23065	COG2136	Putative SAM-dependent methyltransferase
FNB21_RS23075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS23080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNB21_RS23090	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNB21_RS23095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNB21_RS23100	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FNB21_RS23105	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNB21_RS23110	COG0406	alpha-ribazole phosphatase activity
FNB21_RS23120	COG2096	Adenosyltransferase
FNB21_RS23125	COG2962	Rard protein
FNB21_RS23135	COG0523	cobalamin synthesis protein
FNB21_RS23140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FNB21_RS23145	COG0322	excinuclease ABC activity
FNB21_RS23155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNB21_RS23160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNB21_RS23165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNB21_RS23175	COG3011	Protein conserved in bacteria
FNB21_RS23180	COG1595	DNA-templated transcription, initiation
FNB21_RS23200	COG2002	toxin-antitoxin pair type II binding
FNB21_RS23205	COG0534	Mate efflux family protein
FNB21_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS23235	COG1368	sulfuric ester hydrolase activity
FNB21_RS23245	COG3853	Toxic anion resistance protein (TelA)
FNB21_RS23270	COG2234	aminopeptidase activity
FNB21_RS23275	COG5002	protein histidine kinase activity
FNB21_RS23285	COG1823	symporter activity
FNB21_RS23290	COG1523	belongs to the glycosyl hydrolase 13 family
FNB21_RS23295	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS23300	COG2124	cytochrome p450
FNB21_RS23305	COG2112	serine threonine protein kinase
FNB21_RS23315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FNB21_RS23335	COG3361	conserved protein (COG2071)
FNB21_RS23340	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNB21_RS23345	COG1757	Na H antiporter
FNB21_RS23355	COG0833	amino acid
FNB21_RS23360	COG3594	Acyltransferase
FNB21_RS23365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNB21_RS23370	COG0745	RESPONSE REGULATOR receiver
FNB21_RS23375	COG5002	protein histidine kinase activity
FNB21_RS23380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNB21_RS23385	COG3104	oligopeptide transport
FNB21_RS23395	COG0281	malic enzyme
FNB21_RS23400	COG3493	citrate carrier protein
FNB21_RS23405	COG0561	phosphatase activity
FNB21_RS23415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS23425	COG0456	acetyltransferase
FNB21_RS23430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNB21_RS23435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNB21_RS23440	COG0765	amino acid transport
FNB21_RS23445	COG0765	amino acid transport
FNB21_RS23450	COG1126	abc transporter atp-binding protein
FNB21_RS23455	COG0196	riboflavin kinase activity
FNB21_RS23460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS23470	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNB21_RS23490	COG2188	Transcriptional regulator
FNB21_RS23495	COG1070	Carbohydrate kinase
FNB21_RS23500	COG2140	Oxalate decarboxylase
FNB21_RS23505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNB21_RS23530	COG0363	glucosamine-6-phosphate deaminase activity
FNB21_RS23535	COG0738	Major facilitator superfamily
FNB21_RS23560	COG1611	Belongs to the LOG family
FNB21_RS23565	COG0281	malic enzyme
FNB21_RS23570	COG3402	PFAM membrane-flanked domain
FNB21_RS23575	COG3428	Bacterial PH domain
FNB21_RS23590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNB21_RS23595	COG0109	protoheme IX farnesyltransferase activity
FNB21_RS23600	COG4195	phage-related replication protein
FNB21_RS23610	COG0789	Transcriptional regulator
FNB21_RS23645	COG0583	DNA-binding transcription factor activity
FNB21_RS23650	COG0070	glutamate synthase
FNB21_RS23650	COG0069	glutamate synthase activity
FNB21_RS23650	COG0067	glutamate synthase
FNB21_RS23655	COG0493	'glutamate synthase
FNB21_RS23675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNB21_RS23690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNB21_RS23705	COG1846	Transcriptional regulator
FNB21_RS23710	COG1380	Effector of murein hydrolase LrgA
FNB21_RS23715	COG1346	cytolysis
FNB21_RS23720	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS23735	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNB21_RS23740	COG0463	Glycosyl transferase, family 2
FNB21_RS23750	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNB21_RS23755	COG0745	RESPONSE REGULATOR receiver
FNB21_RS23765	COG5583	Uncharacterized small protein (DUF2292)
FNB21_RS23775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FNB21_RS23785	COG4208	sulfate ABC transporter
FNB21_RS23800	COG0745	RESPONSE REGULATOR receiver
FNB21_RS23825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS23835	COG1349	DNA-binding transcription factor activity
FNB21_RS23840	COG1105	Belongs to the carbohydrate kinase PfkB family
FNB21_RS23845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNB21_RS23845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FNB21_RS23845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNB21_RS23850	COG0527	aspartate kinase activity
FNB21_RS23860	COG2032	superoxide dismutase activity
FNB21_RS23865	COG1233	COG1233 Phytoene dehydrogenase and related
FNB21_RS23875	COG0300	oxidoreductase activity
FNB21_RS23880	COG0640	Transcriptional regulator
FNB21_RS23885	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS23890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FNB21_RS23905	COG0733	neurotransmitter:sodium symporter activity
FNB21_RS23915	COG3773	Cell wall hydrolase
FNB21_RS23935	COG0673	inositol 2-dehydrogenase activity
FNB21_RS23940	COG1082	Xylose isomerase domain protein TIM barrel
FNB21_RS23945	COG2094	Belongs to the DNA glycosylase MPG family
FNB21_RS23955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNB21_RS23965	COG0454	-acetyltransferase
FNB21_RS23975	COG2814	Major facilitator Superfamily
FNB21_RS23990	COG3871	stress protein (general stress protein 26)
FNB21_RS24015	COG1595	DNA-templated transcription, initiation
FNB21_RS24025	COG0714	Associated with various cellular activities
FNB21_RS24030	COG4548	von Willebrand factor, type A
FNB21_RS24035	COG0697	spore germination
FNB21_RS24045	COG2207	Transcriptional regulator
FNB21_RS24050	COG1994	Peptidase M50
FNB21_RS24055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS24060	COG1119	ATPase activity
FNB21_RS24075	COG1657	PFAM Prenyltransferase squalene oxidase
FNB21_RS24085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FNB21_RS24085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNB21_RS24105	COG1378	Sugar-specific transcriptional regulator TrmB
FNB21_RS24110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNB21_RS24135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS24170	COG1396	sequence-specific DNA binding
FNB21_RS24185	COG0494	nUDIX hydrolase
FNB21_RS24190	COG1335	isochorismatase
FNB21_RS24195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FNB21_RS24200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNB21_RS24205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNB21_RS24210	COG1098	S1 RNA binding domain
FNB21_RS24215	COG1404	Belongs to the peptidase S8 family
FNB21_RS24220	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS24225	COG1254	Belongs to the acylphosphatase family
FNB21_RS24230	COG2223	nitrite transmembrane transporter activity
FNB21_RS24235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS24245	COG2207	Transcriptional regulator
FNB21_RS24245	COG0662	Cupin 2, conserved barrel domain protein
FNB21_RS24255	COG0488	(ABC) transporter
FNB21_RS24260	COG0697	spore germination
FNB21_RS24265	COG0531	amino acid
FNB21_RS24280	COG1131	(ABC) transporter
FNB21_RS24285	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FNB21_RS24290	COG1757	Na H antiporter
FNB21_RS24295	COG1609	Transcriptional regulator
FNB21_RS24305	COG1533	DNA photolyase activity
FNB21_RS24325	COG0551	DNA topoisomerase type I activity
FNB21_RS24325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNB21_RS24335	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNB21_RS24360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNB21_RS24380	COG1757	Na H antiporter
FNB21_RS24405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNB21_RS24415	COG2720	vancomycin resistance protein
FNB21_RS24455	COG0514	ATP-dependent DNA helicase (RecQ)
FNB21_RS24470	COG1012	belongs to the aldehyde dehydrogenase family
FNB21_RS24485	COG1575	Belongs to the MenA family. Type 1 subfamily
FNB21_RS24490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNB21_RS24505	COG2814	Major facilitator Superfamily
FNB21_RS24510	COG0583	DNA-binding transcription factor activity
FNB21_RS24515	COG1725	Transcriptional regulator
FNB21_RS24520	COG1131	(ABC) transporter
FNB21_RS24530	COG1595	DNA-templated transcription, initiation
FNB21_RS24545	COG1764	response to oxidative stress
FNB21_RS24550	COG1846	Transcriptional regulator
FNB21_RS24565	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
FNB21_RS24575	COG3584	3D domain protein
FNB21_RS24575	COG1388	LysM domain
FNB21_RS24595	COG5002	protein histidine kinase activity
FNB21_RS24600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNB21_RS24605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNB21_RS24610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNB21_RS24625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNB21_RS24645	COG1834	amidinotransferase
FNB21_RS24655	COG1295	ribonuclease BN
FNB21_RS24735	COG0110	maltose O-acetyltransferase activity
FNB21_RS24740	COG0346	lactoylglutathione lyase activity
FNB21_RS24750	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS24760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNB21_RS24770	COG2176	DNA-directed DNA polymerase activity
FNB21_RS24785	COG0114	fumarate hydratase activity
FNB21_RS24795	COG3757	hydrolase, family 25
FNB21_RS24795	COG3409	Peptidoglycan-binding domain 1 protein
FNB21_RS24845	COG0778	Nitroreductase
FNB21_RS24855	COG0300	oxidoreductase activity
FNB21_RS24860	COG3290	protein histidine kinase activity
FNB21_RS24865	COG4565	transcriptional regulatory protein
FNB21_RS24870	COG2851	Citrate transporter
FNB21_RS24880	COG2610	gluconate transmembrane transporter activity
FNB21_RS24885	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS24890	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNB21_RS24915	COG4122	O-methyltransferase activity
FNB21_RS24920	COG0583	DNA-binding transcription factor activity
FNB21_RS24930	COG1301	dicarboxylic acid transport
FNB21_RS24935	COG0019	diaminopimelate decarboxylase activity
FNB21_RS24945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNB21_RS24955	COG4191	Histidine kinase
FNB21_RS24970	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS24975	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS24985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNB21_RS24990	COG1024	Enoyl-CoA hydratase
FNB21_RS25005	COG2045	Belongs to the ComB family
FNB21_RS25010	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS25015	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS25020	COG1024	Enoyl-CoA hydratase
FNB21_RS25035	COG1141	Ferredoxin
FNB21_RS25045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNB21_RS25055	COG0183	Belongs to the thiolase family
FNB21_RS25060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNB21_RS25065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNB21_RS25085	COG1509	lysine 2,3-aminomutase activity
FNB21_RS25095	COG0833	amino acid
FNB21_RS25100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS25115	COG1979	alcohol dehydrogenase
FNB21_RS25120	COG0738	Major facilitator superfamily
FNB21_RS25125	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNB21_RS25145	COG3977	Valine--pyruvate aminotransferase
FNB21_RS25150	COG3773	Cell wall hydrolase
FNB21_RS25155	COG3119	arylsulfatase activity
FNB21_RS25160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNB21_RS25170	COG0531	amino acid
FNB21_RS25175	COG2814	Major facilitator Superfamily
FNB21_RS25180	COG1846	Transcriptional regulator
FNB21_RS25185	COG2409	Drug exporters of the RND superfamily
FNB21_RS25185	COG1033	growth of symbiont in host cell
FNB21_RS25190	COG2202	Pas domain
FNB21_RS25190	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS25195	COG3832	glyoxalase III activity
FNB21_RS25200	COG0640	Transcriptional regulator
FNB21_RS25220	COG3386	PFAM SMP-30 Gluconolaconase
FNB21_RS25230	COG2368	4-hydroxyphenylacetate
FNB21_RS25235	COG3739	integral membrane protein
FNB21_RS25245	COG0326	Molecular chaperone. Has ATPase activity
FNB21_RS25250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNB21_RS25265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNB21_RS25270	COG3409	Peptidoglycan-binding domain 1 protein
FNB21_RS25270	COG3757	hydrolase, family 25
FNB21_RS25280	COG0697	spore germination
FNB21_RS25285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS25300	COG4572	Cation transport regulator
FNB21_RS25305	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FNB21_RS25310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNB21_RS25360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNB21_RS25375	COG0494	nUDIX hydrolase
FNB21_RS25380	COG0702	epimerase
FNB21_RS25385	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS25390	COG1846	Transcriptional regulator
FNB21_RS25395	COG2720	vancomycin resistance protein
FNB21_RS25400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNB21_RS25425	COG0076	glutamate decarboxylase activity
FNB21_RS25455	COG2116	formate transmembrane transporter activity
FNB21_RS25460	COG5609	conserved protein (DUF2294)
FNB21_RS25475	COG2271	Major facilitator Superfamily
FNB21_RS25480	COG0277	FAD linked oxidase domain protein
FNB21_RS25485	COG0840	transmembrane signaling receptor activity
FNB21_RS25495	COG0622	Phosphoesterase
FNB21_RS25505	COG1408	metallophosphoesterase
FNB21_RS25510	COG3663	DNA glycosylase
FNB21_RS25515	COG0791	NLP P60 protein
FNB21_RS25515	COG3883	PFAM NLP P60 protein
FNB21_RS25520	COG1587	Uroporphyrinogen-III synthase
FNB21_RS25525	COG1414	Transcriptional regulator
FNB21_RS25530	COG0439	Biotin carboxylase
FNB21_RS25535	COG0511	ligase activity, forming carbon-carbon bonds
FNB21_RS25545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FNB21_RS25555	COG1914	H( )-stimulated, divalent metal cation uptake system
FNB21_RS25560	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNB21_RS25575	COG0318	PFAM AMP-dependent synthetase and ligase
FNB21_RS25580	COG1268	BioY protein
FNB21_RS25605	COG0431	NADPH-dependent FMN reductase
FNB21_RS25610	COG2197	response regulator
FNB21_RS25635	COG0697	spore germination
FNB21_RS25645	COG2153	protein acetylation
FNB21_RS25650	COG0129	dihydroxy-acid dehydratase activity
FNB21_RS25655	COG2267	carboxylic ester hydrolase activity
FNB21_RS25660	COG1227	inorganic diphosphatase activity
FNB21_RS25680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNB21_RS25690	COG0204	Acyl-transferase
FNB21_RS25695	COG2233	PERMEase
FNB21_RS25700	COG3195	allantoin biosynthetic process
FNB21_RS25700	COG3648	Uricase
FNB21_RS25725	COG1914	H( )-stimulated, divalent metal cation uptake system
FNB21_RS25740	COG1011	Hydrolase
FNB21_RS25745	COG1846	Transcriptional regulator
FNB21_RS25755	COG4974	Belongs to the 'phage' integrase family
FNB21_RS25770	COG0531	amino acid
FNB21_RS25775	COG4302	ethanolamine ammonia-lyase activity
FNB21_RS25780	COG4303	Ethanolamine ammonia lyase large subunit
FNB21_RS25785	COG4819	ethanolamine utilization protein
FNB21_RS25795	COG0833	amino acid
FNB21_RS25805	COG1247	-acetyltransferase
FNB21_RS25810	COG1335	isochorismatase
FNB21_RS25820	COG3403	YqcI/YcgG family
FNB21_RS25825	COG1280	lysine exporter protein (LysE YggA)
FNB21_RS25830	COG2267	carboxylic ester hydrolase activity
FNB21_RS25835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNB21_RS25840	COG0187	DNA topoisomerase II activity
FNB21_RS25845	COG1832	CoA-binding protein
FNB21_RS25850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNB21_RS25855	COG4841	protein insertion into membrane
FNB21_RS25860	COG0824	Thioesterase
FNB21_RS25890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNB21_RS25895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNB21_RS25915	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNB21_RS25950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FNB21_RS25955	COG2068	MobA-Related Protein
FNB21_RS25960	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNB21_RS26015	COG1183	phosphatidylcholine synthase activity
FNB21_RS26030	COG2814	Major facilitator Superfamily
FNB21_RS26035	COG1683	Conserved Protein
FNB21_RS26040	COG1302	Protein conserved in bacteria
FNB21_RS26055	COG1295	ribonuclease BN
FNB21_RS26070	COG2814	Major facilitator Superfamily
FNB21_RS26080	COG2814	Major facilitator Superfamily
FNB21_RS26085	COG0789	Transcriptional regulator
FNB21_RS26095	COG0288	reversible hydration of carbon dioxide
FNB21_RS26100	COG0659	secondary active sulfate transmembrane transporter activity
FNB21_RS26105	COG0745	RESPONSE REGULATOR receiver
FNB21_RS26110	COG5002	protein histidine kinase activity
FNB21_RS26120	COG0477	Major facilitator Superfamily
FNB21_RS26125	COG4282	regulation of fungal-type cell wall biogenesis
FNB21_RS26140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNB21_RS26145	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FNB21_RS26215	COG1363	Peptidase, m42
FNB21_RS26225	COG1114	Component of the transport system for branched-chain amino acids
FNB21_RS26245	COG0004	ammonium transporteR
FNB21_RS26260	COG1252	NADH dehydrogenase
FNB21_RS26265	COG0679	Auxin Efflux Carrier
FNB21_RS26270	COG0281	malic enzyme
FNB21_RS26275	COG1473	amidohydrolase
FNB21_RS26280	COG2271	Major facilitator Superfamily
FNB21_RS26300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FNB21_RS26305	COG0163	prenyltransferase activity
FNB21_RS26310	COG0583	DNA-binding transcription factor activity
FNB21_RS26315	COG0679	Auxin Efflux Carrier
FNB21_RS26335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS26340	COG0247	lactate metabolic process
FNB21_RS26345	COG0277	FAD linked oxidase domain protein
FNB21_RS26350	COG3835	regulator
FNB21_RS26355	COG0693	protein deglycase activity
FNB21_RS26365	COG2610	gluconate transmembrane transporter activity
FNB21_RS26385	COG1131	(ABC) transporter
FNB21_RS26395	COG2197	response regulator
FNB21_RS26430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS26440	COG0586	Pfam SNARE associated Golgi protein
FNB21_RS26445	COG1515	deoxyribonuclease V activity
FNB21_RS26450	COG0584	glycerophosphoryl diester phosphodiesterase
FNB21_RS26495	COG2849	repeat protein
FNB21_RS26500	COG5444	nuclease activity
FNB21_RS26515	COG0534	Mate efflux family protein
FNB21_RS26520	COG1566	PFAM secretion protein HlyD family protein
FNB21_RS26530	COG1846	Transcriptional regulator
FNB21_RS26535	COG0708	Exodeoxyribonuclease III
FNB21_RS26550	COG0673	inositol 2-dehydrogenase activity
FNB21_RS26555	COG1349	DNA-binding transcription factor activity
FNB21_RS26560	COG3853	Toxic anion resistance protein (TelA)
FNB21_RS26570	COG2310	stress, protein
FNB21_RS26575	COG2310	stress, protein
FNB21_RS26580	COG2310	stress, protein
FNB21_RS26585	COG0737	Belongs to the 5'-nucleotidase family
FNB21_RS26605	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FNB21_RS26610	COG1131	(ABC) transporter
FNB21_RS26620	COG2084	Dehydrogenase
FNB21_RS26625	COG1278	Cold shock
FNB21_RS26630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNB21_RS26640	COG0028	Belongs to the TPP enzyme family
FNB21_RS26645	COG1278	Cold shock
FNB21_RS26675	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS26685	COG0427	acetyl-CoA hydrolase
FNB21_RS26690	COG3279	Response regulator of the LytR AlgR family
FNB21_RS26695	COG2323	membrane
FNB21_RS26700	COG2814	Major facilitator Superfamily
FNB21_RS26705	COG3584	3D domain protein
FNB21_RS26705	COG1388	LysM domain
FNB21_RS26710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNB21_RS26735	COG3340	Belongs to the peptidase S51 family
FNB21_RS26765	COG3586	endonuclease activity
FNB21_RS26815	COG0582	viral genome integration into host DNA
FNB21_RS26880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNB21_RS26895	COG3973	AAA domain
FNB21_RS26900	COG0210	DNA helicase
FNB21_RS26915	COG0210	DNA helicase
FNB21_RS26920	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FNB21_RS26925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNB21_RS26925	COG1215	transferase activity, transferring glycosyl groups
FNB21_RS26935	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNB21_RS26935	COG1215	transferase activity, transferring glycosyl groups
FNB21_RS26940	COG1442	glycosyl transferase family 8
FNB21_RS26940	COG1216	Glycosyl transferase, family 2
FNB21_RS26960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNB21_RS26965	COG3955	Domain of unknown function (DUF1919)
FNB21_RS27010	COG5444	nuclease activity
FNB21_RS27040	COG2318	DinB family
FNB21_RS27050	COG0579	oxidoreductase
FNB21_RS27080	COG0488	(ABC) transporter
FNB21_RS27085	COG1486	melibiose metabolic process
FNB21_RS27090	COG0395	ABC-type sugar transport system, permease component
FNB21_RS27095	COG1175	transmembrane transport
FNB21_RS27100	COG1653	transport
FNB21_RS27105	COG1609	Transcriptional regulator
FNB21_RS27125	COG1929	Belongs to the glycerate kinase type-1 family
FNB21_RS27130	COG2610	gluconate transmembrane transporter activity
FNB21_RS27135	COG3835	regulator
FNB21_RS27140	COG1454	alcohol dehydrogenase
FNB21_RS27145	COG3152	Membrane
FNB21_RS27160	COG0492	ferredoxin-NADP+ reductase activity
FNB21_RS27175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNB21_RS27180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS27185	COG3152	Membrane
FNB21_RS27205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FNB21_RS27215	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FNB21_RS27230	COG2390	Transcriptional regulator
FNB21_RS27260	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNB21_RS27265	COG0501	Belongs to the peptidase M48B family
FNB21_RS27270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNB21_RS27275	COG1742	UPF0060 membrane protein
FNB21_RS27280	COG2182	Extracellular solute-binding protein
FNB21_RS27300	COG2031	fatty acid transporter
FNB21_RS27325	COG2391	methyltransferase activity
FNB21_RS27340	COG1979	alcohol dehydrogenase
FNB21_RS27345	COG0583	DNA-binding transcription factor activity
FNB21_RS27355	COG0456	acetyltransferase
FNB21_RS27385	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS27390	COG1063	alcohol dehydrogenase
FNB21_RS27415	COG0025	NhaP-type Na H and K H
FNB21_RS27420	COG1253	flavin adenine dinucleotide binding
FNB21_RS27445	COG4608	Belongs to the ABC transporter superfamily
FNB21_RS27455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNB21_RS27460	COG0601	transmembrane transport
FNB21_RS27465	COG0747	negative chemotaxis
FNB21_RS27475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS27515	COG0626	cystathionine gamma-synthase activity
FNB21_RS27520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNB21_RS27525	COG2814	Major facilitator Superfamily
FNB21_RS27530	COG0583	DNA-binding transcription factor activity
FNB21_RS27540	COG0656	L-ascorbic acid biosynthetic process
FNB21_RS27545	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS27550	COG0693	protein deglycase activity
FNB21_RS27570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNB21_RS27575	COG1733	regulation of RNA biosynthetic process
FNB21_RS27580	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FNB21_RS27585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNB21_RS27590	COG0300	oxidoreductase activity
FNB21_RS27620	COG0640	Transcriptional regulator
FNB21_RS27625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS27630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS27635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS27640	COG1902	pentaerythritol trinitrate reductase activity
FNB21_RS27655	COG1733	regulation of RNA biosynthetic process
FNB21_RS27670	COG0579	oxidoreductase
FNB21_RS27675	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FNB21_RS27680	COG0561	phosphatase activity
FNB21_RS27695	COG0668	transmembrane transport
FNB21_RS27725	COG2309	aminopeptidase activity
FNB21_RS27730	COG1414	Transcriptional regulator
FNB21_RS27735	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNB21_RS27740	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNB21_RS27745	COG0277	FAD linked oxidase domain protein
FNB21_RS27755	COG0277	FAD linked oxidase domain protein
FNB21_RS27760	COG1620	l-lactate permease
FNB21_RS27780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FNB21_RS27785	COG1131	(ABC) transporter
FNB21_RS27805	COG1595	DNA-templated transcription, initiation
FNB21_RS27825	COG4682	membrane
FNB21_RS27840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNB21_RS27845	COG1366	Belongs to the anti-sigma-factor antagonist family
FNB21_RS27850	COG0598	Magnesium transport protein CorA
FNB21_RS27855	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FNB21_RS27865	COG2323	membrane
FNB21_RS27870	COG1876	peptidase activity
FNB21_RS27885	COG5002	protein histidine kinase activity
FNB21_RS27890	COG0745	RESPONSE REGULATOR receiver
FNB21_RS27910	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNB21_RS27915	COG0567	Dehydrogenase, E1 component
FNB21_RS27925	COG2814	Major facilitator Superfamily
FNB21_RS27940	COG2311	Membrane
FNB21_RS28000	COG0347	Belongs to the P(II) protein family
FNB21_RS28005	COG0004	ammonium transporteR
FNB21_RS28010	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FNB21_RS28025	COG0596	Alpha beta hydrolase
FNB21_RS28045	COG0456	acetyltransferase
FNB21_RS28045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FNB21_RS28050	COG1960	acyl-CoA dehydrogenase activity
FNB21_RS28090	COG4604	ABC transporter, ATP-binding protein
FNB21_RS28095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNB21_RS28100	COG1492	cobalamin metabolic process
FNB21_RS28110	COG0531	amino acid
FNB21_RS28120	COG1028	Short-chain dehydrogenase reductase Sdr
FNB21_RS28125	COG2404	hydrolase activity, acting on ester bonds
FNB21_RS28130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNB21_RS28140	COG1609	Transcriptional regulator
FNB21_RS28150	COG2271	Major facilitator Superfamily
FNB21_RS28155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway