locus-tag	class	description
RA13_RS00015	COG2113	Glycine betaine
RA13_RS00020	COG4176	ABC-type proline glycine betaine transport system permease component
RA13_RS00030	COG0477	Major facilitator Superfamily
RA13_RS00035	COG3853	Toxic anion resistance protein (TelA)
RA13_RS00060	COG0861	Integral membrane protein TerC family
RA13_RS00065	COG2310	stress, protein
RA13_RS00070	COG2310	stress, protein
RA13_RS00075	COG2310	stress, protein
RA13_RS00080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RA13_RS00085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RA13_RS00090	COG1121	(ABC) transporter
RA13_RS00095	COG0803	Belongs to the bacterial solute-binding protein 9 family
RA13_RS00100	COG0366	Alpha amylase catalytic
RA13_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS00110	COG0457	Tetratricopeptide repeat
RA13_RS00115	COG1876	peptidase activity
RA13_RS00120	COG1595	DNA-templated transcription, initiation
RA13_RS00125	COG0735	belongs to the Fur family
RA13_RS00140	COG0667	Aldo Keto reductase
RA13_RS00145	COG3012	SEC-C Motif Domain Protein
RA13_RS00145	COG1405	negative regulation of cell septum assembly
RA13_RS00150	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RA13_RS00155	COG0252	asparaginase activity
RA13_RS00160	COG1309	transcriptional regulator
RA13_RS00165	COG0477	Major facilitator Superfamily
RA13_RS00170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RA13_RS00180	COG0805	protein transport
RA13_RS00185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RA13_RS00190	COG3540	Alkaline phosphatase
RA13_RS00195	COG3773	Cell wall hydrolase
RA13_RS00220	COG1131	(ABC) transporter
RA13_RS00225	COG2205	protein histidine kinase activity
RA13_RS00230	COG0745	RESPONSE REGULATOR receiver
RA13_RS00250	COG2721	sulfolactate sulfo-lyase activity
RA13_RS00255	COG2186	Transcriptional regulator
RA13_RS00260	COG4948	Mandelate Racemase Muconate Lactonizing
RA13_RS00265	COG2271	Major facilitator Superfamily
RA13_RS00270	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS00275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RA13_RS00280	COG0784	Response regulator, receiver
RA13_RS00285	COG4191	Histidine kinase
RA13_RS00290	COG2066	Belongs to the glutaminase family
RA13_RS00295	COG1115	amino acid carrier protein
RA13_RS00300	COG2040	homocysteine
RA13_RS00310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RA13_RS00320	COG2188	Transcriptional regulator
RA13_RS00325	COG0363	glucosamine-6-phosphate deaminase activity
RA13_RS00330	COG1263	PTS System
RA13_RS00330	COG2190	(PTS) system
RA13_RS00330	COG2190	(PTS) system
RA13_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS00330	COG1263	PTS System
RA13_RS00330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS00335	COG1301	dicarboxylic acid transport
RA13_RS00340	COG1054	Belongs to the UPF0176 family
RA13_RS00345	COG2207	Transcriptional regulator
RA13_RS00355	COG1404	Belongs to the peptidase S8 family
RA13_RS00370	COG0688	phosphatidylethanolamine metabolic process
RA13_RS00375	COG0586	Pfam SNARE associated Golgi protein
RA13_RS00380	COG1183	phosphatidylcholine synthase activity
RA13_RS00395	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RA13_RS00400	COG0371	Dehydrogenase
RA13_RS00405	COG0697	spore germination
RA13_RS00410	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS00435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RA13_RS00440	COG0463	Glycosyl transferase, family 2
RA13_RS00445	COG1215	transferase activity, transferring glycosyl groups
RA13_RS00445	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RA13_RS00450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RA13_RS00450	COG1215	transferase activity, transferring glycosyl groups
RA13_RS00460	COG2271	Major facilitator Superfamily
RA13_RS00465	COG0584	glycerophosphoryl diester phosphodiesterase
RA13_RS00470	COG1283	sodium-dependent phosphate transmembrane transporter activity
RA13_RS00480	COG2124	cytochrome p450
RA13_RS00485	COG2602	Beta-lactamase
RA13_RS00500	COG1113	amino acid transport
RA13_RS00505	COG1846	Transcriptional regulator
RA13_RS00510	COG1380	Effector of murein hydrolase LrgA
RA13_RS00515	COG1346	cytolysis
RA13_RS00525	COG0642	Histidine kinase
RA13_RS00530	COG0745	RESPONSE REGULATOR receiver
RA13_RS00535	COG0596	Alpha beta hydrolase
RA13_RS00540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RA13_RS00545	COG2808	Putative FMN-binding domain
RA13_RS00550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RA13_RS00560	COG0076	glutamate decarboxylase activity
RA13_RS00585	COG1413	lyase activity
RA13_RS00610	COG0640	Transcriptional regulator
RA13_RS00620	COG5609	conserved protein (DUF2294)
RA13_RS00630	COG0288	reversible hydration of carbon dioxide
RA13_RS00650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RA13_RS00655	COG4856	YbbR-like protein
RA13_RS00660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RA13_RS00665	COG5662	AntiSigma factor
RA13_RS00670	COG1595	DNA-templated transcription, initiation
RA13_RS00700	COG1683	Conserved Protein
RA13_RS00705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RA13_RS00710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RA13_RS00715	COG1737	Transcriptional regulator
RA13_RS00720	COG1263	PTS System
RA13_RS00720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS00725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RA13_RS00730	COG1472	Belongs to the glycosyl hydrolase 3 family
RA13_RS00735	COG3876	Protein conserved in bacteria
RA13_RS00740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RA13_RS00740	COG2207	Transcriptional regulator
RA13_RS00745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RA13_RS00750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS00755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS00760	COG2819	hydrolase of the alpha beta superfamily
RA13_RS00765	COG0385	Bile acid
RA13_RS00770	COG0659	secondary active sulfate transmembrane transporter activity
RA13_RS00775	COG1063	alcohol dehydrogenase
RA13_RS00785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RA13_RS00790	COG0738	Major facilitator superfamily
RA13_RS00820	COG0726	polysaccharide deacetylase
RA13_RS00825	COG2194	sulfuric ester hydrolase activity
RA13_RS00835	COG0489	protein tyrosine kinase activity
RA13_RS00840	COG0860	N-Acetylmuramoyl-L-alanine amidase
RA13_RS00860	COG2226	methyltransferase
RA13_RS00870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RA13_RS00880	COG0101	tRNA pseudouridine synthase activity
RA13_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RA13_RS00890	COG1122	ATPase activity
RA13_RS00895	COG1122	ATPase activity
RA13_RS00900	COG0203	ribosomal protein L17
RA13_RS00910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RA13_RS00920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RA13_RS00930	COG2163	COG2163 Ribosomal protein L14E L6E L27E
RA13_RS00935	COG0024	Methionine aminopeptidase
RA13_RS00945	COG0201	protein transport
RA13_RS00960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RA13_RS00965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RA13_RS00975	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RA13_RS01000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RA13_RS01030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RA13_RS01045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RA13_RS01055	COG0596	Alpha beta hydrolase
RA13_RS01065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RA13_RS01070	COG0049	tRNA binding
RA13_RS01080	COG1358	cellular component organization or biogenesis
RA13_RS01090	COG0085	RNA polymerase activity
RA13_RS01095	COG2813	Specifically methylates the guanine in position
RA13_RS01105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RA13_RS01120	COG0250	Participates in transcription elongation, termination and antitermination
RA13_RS01125	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RA13_RS01135	COG1595	DNA-templated transcription, initiation
RA13_RS01140	COG3688	RNA-binding protein containing a PIN domain
RA13_RS01145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RA13_RS01150	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RA13_RS01155	COG0215	cysteine-tRNA ligase activity
RA13_RS01165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RA13_RS01170	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RA13_RS01175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RA13_RS01180	COG4956	integral membrane protein (PIN domain superfamily)
RA13_RS01185	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
RA13_RS01190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RA13_RS01195	COG0542	response to heat
RA13_RS01200	COG3869	Catalyzes the specific phosphorylation of arginine residues in
RA13_RS01205	COG3880	PFAM UvrB UvrC protein
RA13_RS01210	COG4463	regulation of RNA biosynthetic process
RA13_RS01290	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RA13_RS01295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RA13_RS01300	COG1396	sequence-specific DNA binding
RA13_RS01305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RA13_RS01310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RA13_RS01315	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RA13_RS01320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RA13_RS01325	COG0512	Glutamine amidotransferase of anthranilate synthase
RA13_RS01330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RA13_RS01335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RA13_RS01340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RA13_RS01355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RA13_RS01360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
RA13_RS01365	COG0037	tRNA processing
RA13_RS01370	COG0515	serine threonine protein kinase
RA13_RS01375	COG2304	oxidoreductase activity
RA13_RS01380	COG2208	phosphoserine phosphatase activity
RA13_RS01395	COG1098	S1 RNA binding domain
RA13_RS01400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RA13_RS01415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
RA13_RS01420	COG3956	TIGRFAM MazG family protein
RA13_RS01425	COG2244	polysaccharide biosynthetic process
RA13_RS01430	COG2002	toxin-antitoxin pair type II binding
RA13_RS01435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RA13_RS01450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RA13_RS01455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RA13_RS01470	COG0251	oxidation-reduction process
RA13_RS01475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RA13_RS01480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RA13_RS01490	COG4466	Protein conserved in bacteria
RA13_RS01500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RA13_RS01505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RA13_RS01510	COG3583	domain protein
RA13_RS01510	COG3584	3D domain protein
RA13_RS01520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RA13_RS01520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RA13_RS01525	COG2002	toxin-antitoxin pair type II binding
RA13_RS01530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RA13_RS01535	COG2827	Endonuclease containing a URI domain
RA13_RS01540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RA13_RS01550	COG1774	PSP1 C-terminal conserved region
RA13_RS01555	COG0470	DNA polymerase III
RA13_RS01560	COG1728	Protein conserved in bacteria
RA13_RS01565	COG3870	Protein conserved in bacteria
RA13_RS01570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RA13_RS01580	COG3853	Toxic anion resistance protein (TelA)
RA13_RS01585	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
RA13_RS01630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RA13_RS01635	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RA13_RS01640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RA13_RS01650	COG0590	tRNA wobble adenosine to inosine editing
RA13_RS01655	COG1335	isochorismatase
RA13_RS01660	COG3858	chitin binding
RA13_RS01660	COG1388	LysM domain
RA13_RS01665	COG1428	Deoxynucleoside kinase
RA13_RS01670	COG1428	Deoxynucleoside kinase
RA13_RS01695	COG1686	Belongs to the peptidase S11 family
RA13_RS01700	COG0517	IMP dehydrogenase activity
RA13_RS01700	COG0516	GMP reductase activity
RA13_RS01765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RA13_RS01770	COG0187	DNA topoisomerase II activity
RA13_RS01780	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RA13_RS01785	COG2501	S4 domain
RA13_RS01790	COG0592	DNA-directed DNA polymerase activity
RA13_RS01795	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RA13_RS01805	COG0594	ribonuclease P activity
RA13_RS01810	COG0706	membrane insertase activity
RA13_RS01815	COG1847	R3H domain protein
RA13_RS01825	COG0445	tRNA wobble uridine modification
RA13_RS01835	COG1475	DNA binding
RA13_RS01845	COG1192	Involved in chromosome partitioning
RA13_RS01850	COG1475	DNA binding
RA13_RS01860	COG3949	Membrane
RA13_RS01865	COG4481	Protein conserved in bacteria
RA13_RS01870	COG0243	molybdopterin cofactor binding
RA13_RS01875	COG0012	GTP binding
RA13_RS01880	COG0360	Binds together with S18 to 16S ribosomal RNA
RA13_RS01885	COG0629	single-stranded DNA binding
RA13_RS01900	COG1802	Transcriptional regulator
RA13_RS01905	COG0697	spore germination
RA13_RS01910	COG0708	Exodeoxyribonuclease III
RA13_RS01915	COG2169	Transcriptional regulator
RA13_RS01925	COG1609	Transcriptional regulator
RA13_RS01930	COG0346	lactoylglutathione lyase activity
RA13_RS01940	COG1331	Highly conserved protein containing a thioredoxin domain
RA13_RS01950	COG2856	Zn peptidase
RA13_RS01965	COG2205	protein histidine kinase activity
RA13_RS01970	COG0745	RESPONSE REGULATOR receiver
RA13_RS01985	COG4585	Histidine kinase
RA13_RS01990	COG2197	response regulator
RA13_RS01995	COG2409	Drug exporters of the RND superfamily
RA13_RS02005	COG4978	Transcriptional regulator
RA13_RS02005	COG0789	Transcriptional regulator
RA13_RS02010	COG1802	Transcriptional regulator
RA13_RS02015	COG0473	3-isopropylmalate dehydrogenase activity
RA13_RS02025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RA13_RS02030	COG2271	Major facilitator Superfamily
RA13_RS02045	COG1733	regulation of RNA biosynthetic process
RA13_RS02050	COG5577	PFAM Coat F domain
RA13_RS02060	COG4241	membrane
RA13_RS02065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
RA13_RS02070	COG0359	binds to the 23S rRNA
RA13_RS02075	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RA13_RS02080	COG2807	transmembrane transport
RA13_RS02085	COG3093	addiction module antidote protein HigA
RA13_RS02100	COG0305	Participates in initiation and elongation during chromosome replication
RA13_RS02105	COG0346	lactoylglutathione lyase activity
RA13_RS02135	COG0745	RESPONSE REGULATOR receiver
RA13_RS02140	COG5002	protein histidine kinase activity
RA13_RS02145	COG4863	YycH protein
RA13_RS02150	COG4853	Protein conserved in bacteria
RA13_RS02155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RA13_RS02160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RA13_RS02180	COG0488	(ABC) transporter
RA13_RS02190	COG3829	transcription factor binding
RA13_RS02195	COG0640	Transcriptional regulator
RA13_RS02200	COG5658	integral membrane protein
RA13_RS02205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RA13_RS02210	COG0833	amino acid
RA13_RS02215	COG0010	Belongs to the arginase family
RA13_RS02220	COG0456	acetyltransferase
RA13_RS02225	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
RA13_RS02235	COG1063	alcohol dehydrogenase
RA13_RS02245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RA13_RS02275	COG2003	Belongs to the UPF0758 family
RA13_RS02340	COG2323	membrane
RA13_RS02345	COG0038	chloride channel
RA13_RS02350	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
RA13_RS02355	COG1131	(ABC) transporter
RA13_RS02375	COG1113	amino acid transport
RA13_RS02385	COG3634	alkyl hydroperoxide reductase activity
RA13_RS02390	COG0450	alkyl hydroperoxide reductase
RA13_RS02405	COG2610	gluconate transmembrane transporter activity
RA13_RS02410	COG1070	Carbohydrate kinase
RA13_RS02415	COG1802	Transcriptional regulator
RA13_RS02420	COG3835	regulator
RA13_RS02425	COG2610	gluconate transmembrane transporter activity
RA13_RS02430	COG1929	Belongs to the glycerate kinase type-1 family
RA13_RS02435	COG5039	Polysaccharide pyruvyl transferase
RA13_RS02475	COG1309	transcriptional regulator
RA13_RS02480	COG1917	Cupin 2, conserved barrel domain protein
RA13_RS02485	COG2311	Membrane
RA13_RS02490	COG1714	RDD family
RA13_RS02500	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS02505	COG1309	transcriptional regulator
RA13_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS02515	COG0326	Molecular chaperone. Has ATPase activity
RA13_RS02520	COG2814	Major facilitator Superfamily
RA13_RS02540	COG0667	Aldo Keto reductase
RA13_RS02545	COG1349	DNA-binding transcription factor activity
RA13_RS02560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RA13_RS02565	COG3962	Belongs to the TPP enzyme family
RA13_RS02570	COG1082	Xylose isomerase domain protein TIM barrel
RA13_RS02575	COG2814	Major facilitator Superfamily
RA13_RS02580	COG0673	inositol 2-dehydrogenase activity
RA13_RS02585	COG1082	Xylose isomerase domain protein TIM barrel
RA13_RS02600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RA13_RS02610	COG0745	RESPONSE REGULATOR receiver
RA13_RS02615	COG2205	protein histidine kinase activity
RA13_RS02620	COG1136	(ABC) transporter
RA13_RS02625	COG0577	efflux transmembrane transporter activity
RA13_RS02630	COG5294	Protein conserved in bacteria
RA13_RS02655	COG0561	phosphatase activity
RA13_RS02660	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
RA13_RS02670	COG3192	ethanolamine utilization protein
RA13_RS02680	COG2390	Transcriptional regulator
RA13_RS02685	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RA13_RS02690	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RA13_RS02695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RA13_RS02705	COG0010	Belongs to the arginase family
RA13_RS02710	COG1228	amidohydrolase
RA13_RS02715	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RA13_RS02720	COG2986	histidine ammonia-lyase
RA13_RS02780	COG3507	Belongs to the glycosyl hydrolase 43 family
RA13_RS02790	COG1181	Belongs to the D-alanine--D-alanine ligase family
RA13_RS02805	COG3977	Valine--pyruvate aminotransferase
RA13_RS02810	COG1263	PTS System
RA13_RS02810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS02810	COG2190	(PTS) system
RA13_RS02815	COG2723	6-phospho-beta-galactosidase activity
RA13_RS02820	COG0589	response to stress
RA13_RS02850	COG0697	spore germination
RA13_RS02930	COG2755	lipolytic protein G-D-S-L family
RA13_RS02930	COG3401	FG-GAP repeat protein
RA13_RS02935	COG1357	PFAM Pentapeptide repeats (8 copies)
RA13_RS02940	COG0346	lactoylglutathione lyase activity
RA13_RS02945	COG0513	Belongs to the DEAD box helicase family
RA13_RS02950	COG2270	Major facilitator Superfamily
RA13_RS02960	COG3711	transcriptional antiterminator
RA13_RS02970	COG2851	Citrate transporter
RA13_RS02975	COG0693	protein deglycase activity
RA13_RS02975	COG0753	catalase activity
RA13_RS02990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RA13_RS02995	COG0500	methyltransferase
RA13_RS03000	COG2610	gluconate transmembrane transporter activity
RA13_RS03005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RA13_RS03010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RA13_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS03020	COG3290	protein histidine kinase activity
RA13_RS03020	COG3829	transcription factor binding
RA13_RS03025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RA13_RS03030	COG4894	glucomannan catabolic process
RA13_RS03045	COG2195	Cleaves the N-terminal amino acid of tripeptides
RA13_RS03055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RA13_RS03065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS03070	COG2508	Transcriptional regulator
RA13_RS03075	COG3842	ATPase activity
RA13_RS03080	COG0726	polysaccharide deacetylase
RA13_RS03090	COG3493	citrate carrier protein
RA13_RS03095	COG1271	oxidase subunit
RA13_RS03100	COG1294	oxidase, subunit
RA13_RS03105	COG4988	ABC transporter
RA13_RS03110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RA13_RS03115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RA13_RS03120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RA13_RS03125	COG1595	DNA-templated transcription, initiation
RA13_RS03145	COG1131	(ABC) transporter
RA13_RS03150	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RA13_RS03155	COG2814	Major facilitator Superfamily
RA13_RS03160	COG0753	catalase activity
RA13_RS03165	COG2094	Belongs to the DNA glycosylase MPG family
RA13_RS03175	COG3711	transcriptional antiterminator
RA13_RS03175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS03180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RA13_RS03185	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RA13_RS03190	COG1447	Phosphotransferase system cellobiose-specific component IIA
RA13_RS03195	COG1486	melibiose metabolic process
RA13_RS03200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RA13_RS03205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
RA13_RS03215	COG1696	Membrane protein involved in D-alanine export
RA13_RS03220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS03230	COG0569	domain protein
RA13_RS03240	COG2357	RelA SpoT domain protein
RA13_RS03245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RA13_RS03250	COG1846	Transcriptional regulator
RA13_RS03255	COG0457	Tetratricopeptide repeat
RA13_RS03260	COG2234	aminopeptidase activity
RA13_RS03265	COG5522	Integral membrane protein (intg_mem_TP0381)
RA13_RS03270	COG1442	glycosyl transferase family 8
RA13_RS03275	COG3711	transcriptional antiterminator
RA13_RS03280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS03280	COG1263	PTS System
RA13_RS03285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RA13_RS03290	COG0346	lactoylglutathione lyase activity
RA13_RS03295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RA13_RS03300	COG4895	conserved protein (DUF2196)
RA13_RS03330	COG1131	(ABC) transporter
RA13_RS03335	COG1346	cytolysis
RA13_RS03345	COG0583	DNA-binding transcription factor activity
RA13_RS03350	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
RA13_RS03355	COG0352	thiamine-phosphate diphosphorylase activity
RA13_RS03360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RA13_RS03365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS03370	COG3162	membrane
RA13_RS03390	COG1309	transcriptional regulator
RA13_RS03395	COG2246	polysaccharide biosynthetic process
RA13_RS03400	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RA13_RS03405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
RA13_RS03410	COG2261	transglycosylase associated protein
RA13_RS03415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RA13_RS03420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RA13_RS03430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RA13_RS03445	COG0772	Belongs to the SEDS family
RA13_RS03450	COG0778	Nitroreductase
RA13_RS03455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RA13_RS03470	COG3711	transcriptional antiterminator
RA13_RS03485	COG1621	beta-fructofuranosidase activity
RA13_RS03500	COG0351	phosphomethylpyrimidine kinase
RA13_RS03505	COG1695	Transcriptional regulator
RA13_RS03520	COG1216	Glycosyl transferase, family 2
RA13_RS03525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RA13_RS03530	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS03540	COG2233	PERMEase
RA13_RS03545	COG2363	Small membrane protein
RA13_RS03555	COG0463	Glycosyl transferase, family 2
RA13_RS03560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RA13_RS03565	COG0456	acetyltransferase
RA13_RS03570	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
RA13_RS03575	COG1088	dTDP-glucose 4,6-dehydratase activity
RA13_RS03585	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RA13_RS03595	COG2814	Major facilitator Superfamily
RA13_RS03600	COG2814	Major facilitator Superfamily
RA13_RS03605	COG3253	May function as heme-dependent peroxidase
RA13_RS03610	COG0280	phosphate acetyltransferase
RA13_RS03620	COG0583	DNA-binding transcription factor activity
RA13_RS03625	COG0095	Lipoate-protein ligase
RA13_RS03630	COG0697	spore germination
RA13_RS03640	COG4844	belongs to the
RA13_RS03645	COG1078	dGTPase activity
RA13_RS03650	COG3465	dGTPase activity
RA13_RS03655	COG0531	amino acid
RA13_RS03660	COG1846	Transcriptional regulator
RA13_RS03665	COG1942	4-Oxalocrotonate Tautomerase
RA13_RS03670	COG1994	Peptidase M50
RA13_RS03680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RA13_RS03685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RA13_RS03690	COG0010	Belongs to the arginase family
RA13_RS03700	COG1131	(ABC) transporter
RA13_RS03730	COG0457	Tetratricopeptide repeat
RA13_RS03735	COG1388	LysM domain
RA13_RS03740	COG3391	amine dehydrogenase activity
RA13_RS03745	COG3391	amine dehydrogenase activity
RA13_RS03770	COG4506	Protein conserved in bacteria
RA13_RS03775	COG0018	arginyl-trna synthetase
RA13_RS03785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RA13_RS03795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RA13_RS03800	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
RA13_RS03805	COG1140	nitrate reductase beta subunit
RA13_RS03810	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
RA13_RS03815	COG2181	nitrate reductase activity
RA13_RS03820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RA13_RS03825	COG1132	(ABC) transporter
RA13_RS03830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RA13_RS03840	COG4294	response to UV
RA13_RS03845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RA13_RS03850	COG0247	lactate metabolic process
RA13_RS03850	COG2181	nitrate reductase activity
RA13_RS03855	COG1960	acyl-CoA dehydrogenase activity
RA13_RS03860	COG3343	RNA polymerase activity
RA13_RS03865	COG0504	CTP synthase activity
RA13_RS03870	COG4821	SIS domain
RA13_RS03875	COG2204	response regulator
RA13_RS03880	COG0191	fructose-bisphosphate aldolase activity
RA13_RS03890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RA13_RS03895	COG1494	fructose-1,6-bisphosphatase
RA13_RS03900	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
RA13_RS03905	COG0254	rRNA binding
RA13_RS03915	COG0281	malic enzyme
RA13_RS03920	COG0679	Auxin Efflux Carrier
RA13_RS03925	COG0789	Transcriptional regulator
RA13_RS03930	COG0346	lactoylglutathione lyase activity
RA13_RS03935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RA13_RS03940	COG2890	protein-(glutamine-N5) methyltransferase activity
RA13_RS03960	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RA13_RS03965	COG0009	L-threonylcarbamoyladenylate synthase
RA13_RS03970	COG1971	Probably functions as a manganese efflux pump
RA13_RS03975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RA13_RS03980	COG0698	ribose 5-phosphate isomerase
RA13_RS03985	COG4475	Protein of unknown function (DUF436)
RA13_RS03990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RA13_RS03995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RA13_RS04015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RA13_RS04020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RA13_RS04030	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RA13_RS04035	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RA13_RS04040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RA13_RS04050	COG4836	Membrane
RA13_RS04060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RA13_RS04065	COG2385	sporulation resulting in formation of a cellular spore
RA13_RS04075	COG2304	oxidoreductase activity
RA13_RS04080	COG2304	oxidoreductase activity
RA13_RS04085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RA13_RS04095	COG0457	Tetratricopeptide repeat
RA13_RS04100	COG1994	Peptidase M50
RA13_RS04105	COG3237	CsbD-like
RA13_RS04110	COG0831	urea catabolic process
RA13_RS04120	COG0804	urea catabolic process
RA13_RS04125	COG1959	2 iron, 2 sulfur cluster binding
RA13_RS04130	COG2910	NAD(P)H-binding
RA13_RS04140	COG0789	Transcriptional regulator
RA13_RS04145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RA13_RS04155	COG2089	acid synthase
RA13_RS04170	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
RA13_RS04175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RA13_RS04180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS04185	COG1086	Polysaccharide biosynthesis protein
RA13_RS04195	COG1247	-acetyltransferase
RA13_RS04200	COG0739	heme binding
RA13_RS04210	COG0671	phosphoesterase, PA-phosphatase related
RA13_RS04215	COG0772	Belongs to the SEDS family
RA13_RS04220	COG0347	Belongs to the P(II) protein family
RA13_RS04225	COG0004	ammonium transporteR
RA13_RS04235	COG1335	isochorismatase
RA13_RS04240	COG0477	Major facilitator Superfamily
RA13_RS04245	COG1953	Uracil, thiamine, allantoin
RA13_RS04250	COG2814	Major facilitator Superfamily
RA13_RS04255	COG1846	Transcriptional regulator
RA13_RS04265	COG1609	Transcriptional regulator
RA13_RS04270	COG1077	Cell shape determining protein MreB Mrl
RA13_RS04275	COG4786	Flagellar basal body rod
RA13_RS04280	COG4786	Flagellar basal body rod
RA13_RS04285	COG0457	Tetratricopeptide repeat
RA13_RS04295	COG1970	mechanosensitive ion channel activity
RA13_RS04310	COG0629	single-stranded DNA binding
RA13_RS04315	COG1349	DNA-binding transcription factor activity
RA13_RS04320	COG0561	phosphatase activity
RA13_RS04325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RA13_RS04330	COG4715	Zinc finger, swim domain protein
RA13_RS04340	COG3944	biosynthesis protein
RA13_RS04345	COG0489	protein tyrosine kinase activity
RA13_RS04350	COG4464	protein tyrosine phosphatase activity
RA13_RS04360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RA13_RS04380	COG5444	nuclease activity
RA13_RS04385	COG2849	repeat protein
RA13_RS04415	COG0583	DNA-binding transcription factor activity
RA13_RS04420	COG0655	NAD(P)H dehydrogenase (quinone) activity
RA13_RS04430	COG2059	Chromate
RA13_RS04435	COG2059	Chromate
RA13_RS04440	COG1522	sequence-specific DNA binding
RA13_RS04445	COG0405	Gamma-glutamyltransferase
RA13_RS04455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RA13_RS04470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS04475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RA13_RS04485	COG5337	Spore coat protein CotH
RA13_RS04495	COG0028	Belongs to the TPP enzyme family
RA13_RS04500	COG3527	Alpha-acetolactate decarboxylase
RA13_RS04505	COG2249	NAD(P)H dehydrogenase (quinone) activity
RA13_RS04515	COG3103	Sh3 type 3 domain protein
RA13_RS04520	COG1879	ABC-type sugar transport system periplasmic component
RA13_RS04525	COG1172	Belongs to the binding-protein-dependent transport system permease family
RA13_RS04530	COG1129	ABC transporter
RA13_RS04535	COG1869	D-ribose catabolic process
RA13_RS04540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RA13_RS04545	COG1609	Transcriptional regulator
RA13_RS04555	COG0531	amino acid
RA13_RS04560	COG0697	spore germination
RA13_RS04565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RA13_RS04575	COG2843	Capsule synthesis protein
RA13_RS04580	COG0791	NLP P60 protein
RA13_RS04585	COG0561	phosphatase activity
RA13_RS04590	COG1316	TRANSCRIPTIONal
RA13_RS04595	COG2814	Major facilitator Superfamily
RA13_RS04610	COG0814	amino acid
RA13_RS04615	COG0697	spore germination
RA13_RS04620	COG1482	cell wall glycoprotein biosynthetic process
RA13_RS04625	COG4193	domain, Protein
RA13_RS04630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RA13_RS04635	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RA13_RS04640	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RA13_RS04650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RA13_RS04655	COG1682	transport, permease protein
RA13_RS04660	COG1134	teichoic acid transport
RA13_RS04665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RA13_RS04670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RA13_RS04675	COG1316	TRANSCRIPTIONal
RA13_RS04685	COG2247	cell wall binding repeat
RA13_RS04685	COG2385	sporulation resulting in formation of a cellular spore
RA13_RS04690	COG2247	cell wall binding repeat
RA13_RS04690	COG0860	N-Acetylmuramoyl-L-alanine amidase
RA13_RS04710	COG0297	glycogen (starch) synthase activity
RA13_RS04710	COG0438	transferase activity, transferring glycosyl groups
RA13_RS04715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RA13_RS04720	COG3307	-O-antigen
RA13_RS04725	COG3206	protein involved in exopolysaccharide biosynthesis
RA13_RS04730	COG1215	transferase activity, transferring glycosyl groups
RA13_RS04735	COG0438	transferase activity, transferring glycosyl groups
RA13_RS04740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RA13_RS04745	COG1316	TRANSCRIPTIONal
RA13_RS04750	COG1739	Uncharacterized protein family UPF0029
RA13_RS04755	COG4585	Histidine kinase
RA13_RS04760	COG2197	response regulator
RA13_RS04765	COG1307	EDD domain protein, DegV family
RA13_RS04770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
RA13_RS04780	COG1040	competence protein
RA13_RS04790	COG2747	anti-sigma28 factor FlgM
RA13_RS04795	COG3418	PFAM FlgN family protein
RA13_RS04800	COG4786	Flagellar basal body rod
RA13_RS04800	COG1256	bacterial-type flagellum assembly
RA13_RS04805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RA13_RS04815	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
RA13_RS04820	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RA13_RS04825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RA13_RS04830	COG1334	flagellar protein FlaG
RA13_RS04835	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
RA13_RS04840	COG1516	flagellar protein fliS
RA13_RS04855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RA13_RS04860	COG0653	protein targeting
RA13_RS04870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS04875	COG2010	Cytochrome c
RA13_RS04880	COG2884	Cell division ATP-binding protein ftsE
RA13_RS04885	COG2177	Part of the ABC transporter FtsEX involved in
RA13_RS04890	COG0793	Belongs to the peptidase S41A family
RA13_RS04890	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS04900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RA13_RS04910	COG2814	Major facilitator Superfamily
RA13_RS04915	COG1309	transcriptional regulator
RA13_RS04920	COG3848	Pyruvate phosphate dikinase
RA13_RS04920	COG0574	Belongs to the PEP-utilizing enzyme family
RA13_RS04925	COG4897	Protein conserved in bacteria
RA13_RS04935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RA13_RS04950	COG3595	metallopeptidase activity
RA13_RS04955	COG1983	PspC domain protein
RA13_RS04960	COG1950	PFAM Membrane protein of
RA13_RS04965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RA13_RS04970	COG2188	Transcriptional regulator
RA13_RS04980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RA13_RS04985	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
RA13_RS04990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RA13_RS04995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RA13_RS05000	COG0546	phosphoglycolate phosphatase activity
RA13_RS05005	COG0110	maltose O-acetyltransferase activity
RA13_RS05010	COG5297	Belongs to the glycosyl hydrolase family 6
RA13_RS05015	COG4990	cell redox homeostasis
RA13_RS05025	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RA13_RS05030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RA13_RS05035	COG0131	Imidazoleglycerol-phosphate dehydratase
RA13_RS05045	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RA13_RS05050	COG0107	imidazoleglycerol-phosphate synthase activity
RA13_RS05055	COG0140	phosphoribosyl-ATP diphosphatase activity
RA13_RS05055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RA13_RS05060	COG1247	-acetyltransferase
RA13_RS05075	COG0457	Tetratricopeptide repeat
RA13_RS05080	COG3883	PFAM NLP P60 protein
RA13_RS05080	COG0791	NLP P60 protein
RA13_RS05085	COG0492	ferredoxin-NADP+ reductase activity
RA13_RS05090	COG1051	belongs to the nudix hydrolase family
RA13_RS05095	COG1660	Displays ATPase and GTPase activities
RA13_RS05100	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RA13_RS05110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS05115	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RA13_RS05120	COG4290	ribonuclease
RA13_RS05125	COG0745	RESPONSE REGULATOR receiver
RA13_RS05130	COG5002	protein histidine kinase activity
RA13_RS05135	COG1136	(ABC) transporter
RA13_RS05140	COG0577	efflux transmembrane transporter activity
RA13_RS05145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RA13_RS05155	COG0659	secondary active sulfate transmembrane transporter activity
RA13_RS05160	COG1694	Mazg nucleotide pyrophosphohydrolase
RA13_RS05165	COG1611	Belongs to the LOG family
RA13_RS05190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RA13_RS05195	COG2076	Multidrug Resistance protein
RA13_RS05200	COG2076	Multidrug Resistance protein
RA13_RS05205	COG1309	transcriptional regulator
RA13_RS05220	COG1621	beta-fructofuranosidase activity
RA13_RS05240	COG1131	(ABC) transporter
RA13_RS05260	COG2272	Belongs to the type-B carboxylesterase lipase family
RA13_RS05265	COG1396	sequence-specific DNA binding
RA13_RS05270	COG3944	biosynthesis protein
RA13_RS05275	COG0489	protein tyrosine kinase activity
RA13_RS05280	COG1086	Polysaccharide biosynthesis protein
RA13_RS05285	COG0438	transferase activity, transferring glycosyl groups
RA13_RS05290	COG1215	transferase activity, transferring glycosyl groups
RA13_RS05295	COG0438	transferase activity, transferring glycosyl groups
RA13_RS05305	COG1216	Glycosyl transferase, family 2
RA13_RS05310	COG5039	Polysaccharide pyruvyl transferase
RA13_RS05315	COG1216	Glycosyl transferase, family 2
RA13_RS05320	COG2244	polysaccharide biosynthetic process
RA13_RS05325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RA13_RS05330	COG0110	maltose O-acetyltransferase activity
RA13_RS05335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RA13_RS05340	COG5039	Polysaccharide pyruvyl transferase
RA13_RS05350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RA13_RS05355	COG1620	l-lactate permease
RA13_RS05360	COG2186	Transcriptional regulator
RA13_RS05365	COG2208	phosphoserine phosphatase activity
RA13_RS05370	COG0247	lactate metabolic process
RA13_RS05375	COG1139	Iron-sulfur cluster binding protein
RA13_RS05380	COG1556	Lactate utilization protein
RA13_RS05390	COG1113	amino acid transport
RA13_RS05395	COG0697	spore germination
RA13_RS05400	COG0583	DNA-binding transcription factor activity
RA13_RS05405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RA13_RS05410	COG1609	Transcriptional regulator
RA13_RS05415	COG2814	Major facilitator Superfamily
RA13_RS05420	COG2390	Transcriptional regulator
RA13_RS05425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RA13_RS05430	COG0126	phosphoglycerate kinase activity
RA13_RS05440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RA13_RS05450	COG2234	aminopeptidase activity
RA13_RS05460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RA13_RS05465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS05485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RA13_RS05500	COG0456	acetyltransferase
RA13_RS05505	COG4640	response to antibiotic
RA13_RS05510	COG3064	Membrane
RA13_RS05520	COG1510	regulation of RNA biosynthetic process
RA13_RS05525	COG1125	glycine betaine transport
RA13_RS05525	COG0517	IMP dehydrogenase activity
RA13_RS05530	COG1174	glycine betaine transport
RA13_RS05535	COG1732	Glycine betaine
RA13_RS05540	COG1174	glycine betaine transport
RA13_RS05545	COG1510	regulation of RNA biosynthetic process
RA13_RS05550	COG1125	glycine betaine transport
RA13_RS05550	COG0517	IMP dehydrogenase activity
RA13_RS05560	COG1732	Glycine betaine
RA13_RS05565	COG1174	glycine betaine transport
RA13_RS05570	COG0840	transmembrane signaling receptor activity
RA13_RS05575	COG1733	regulation of RNA biosynthetic process
RA13_RS05580	COG1396	sequence-specific DNA binding
RA13_RS05585	COG1396	sequence-specific DNA binding
RA13_RS05590	COG1476	TRANSCRIPTIONal
RA13_RS05595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RA13_RS05600	COG1647	Serine aminopeptidase, S33
RA13_RS05605	COG0557	exoribonuclease II activity
RA13_RS05610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RA13_RS05625	COG0673	inositol 2-dehydrogenase activity
RA13_RS05630	COG1937	Protein conserved in bacteria
RA13_RS05635	COG2608	mercury ion transmembrane transporter activity
RA13_RS05640	COG2217	Heavy metal translocating P-type atpase
RA13_RS05645	COG2217	Heavy metal translocating P-type atpase
RA13_RS05650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RA13_RS05655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RA13_RS05665	COG2860	membrane
RA13_RS05670	COG3973	AAA domain
RA13_RS05675	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RA13_RS05700	COG0656	L-ascorbic acid biosynthetic process
RA13_RS05710	COG4149	molybdate abc transporter
RA13_RS05715	COG0725	ABC transporter, periplasmic molybdate-binding protein
RA13_RS05720	COG1910	domain protein
RA13_RS05725	COG1368	sulfuric ester hydrolase activity
RA13_RS05730	COG1988	membrane-bound metal-dependent
RA13_RS05745	COG0531	amino acid
RA13_RS05755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RA13_RS05760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS05765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS05770	COG1120	ATPase activity
RA13_RS05775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RA13_RS05780	COG1136	(ABC) transporter
RA13_RS05785	COG0577	efflux transmembrane transporter activity
RA13_RS05795	COG2140	Oxalate decarboxylase
RA13_RS05805	COG1191	sigma factor activity
RA13_RS05815	COG0745	RESPONSE REGULATOR receiver
RA13_RS05820	COG2205	protein histidine kinase activity
RA13_RS05825	COG3386	PFAM SMP-30 Gluconolaconase
RA13_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS05835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RA13_RS05840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS05845	COG1120	ATPase activity
RA13_RS05850	COG2096	Adenosyltransferase
RA13_RS05855	COG2814	Major facilitator Superfamily
RA13_RS05860	COG4758	membrane
RA13_RS05865	COG1842	Phage shock protein A
RA13_RS05870	COG3595	metallopeptidase activity
RA13_RS05875	COG4758	membrane
RA13_RS05880	COG4585	Histidine kinase
RA13_RS05885	COG2197	response regulator
RA13_RS05910	COG0114	fumarate hydratase activity
RA13_RS05915	COG1309	transcriptional regulator
RA13_RS05925	COG2770	Histidine kinase
RA13_RS05925	COG2205	protein histidine kinase activity
RA13_RS05930	COG0745	RESPONSE REGULATOR receiver
RA13_RS05935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RA13_RS05940	COG0783	Belongs to the Dps family
RA13_RS05945	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS05960	COG1120	ATPase activity
RA13_RS05970	COG0477	Major facilitator Superfamily
RA13_RS05975	COG1846	Transcriptional regulator
RA13_RS05980	COG5577	PFAM Coat F domain
RA13_RS06000	COG1024	Enoyl-CoA hydratase
RA13_RS06000	COG1250	3-hydroxyacyl-CoA dehydrogenase
RA13_RS06005	COG0183	Belongs to the thiolase family
RA13_RS06010	COG1960	acyl-CoA dehydrogenase activity
RA13_RS06015	COG1393	Belongs to the ArsC family
RA13_RS06020	COG0509	glycine decarboxylation via glycine cleavage system
RA13_RS06030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
RA13_RS06035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS06045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RA13_RS06050	COG2011	ABC-type metal ion transport system permease component
RA13_RS06055	COG1464	Belongs to the NlpA lipoprotein family
RA13_RS06060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RA13_RS06070	COG0396	ATPase activity
RA13_RS06075	COG0719	Fe-S assembly protein
RA13_RS06080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RA13_RS06085	COG0822	iron-sulfur transferase activity
RA13_RS06090	COG0719	Fe-S assembly protein
RA13_RS06095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RA13_RS06100	COG0322	excinuclease ABC activity
RA13_RS06105	COG2222	sugar isomerase
RA13_RS06110	COG1653	transport
RA13_RS06115	COG1175	transmembrane transport
RA13_RS06120	COG0395	ABC-type sugar transport system, permease component
RA13_RS06125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RA13_RS06130	COG2188	Transcriptional regulator
RA13_RS06135	COG3842	ATPase activity
RA13_RS06145	COG2356	endonuclease I
RA13_RS06150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RA13_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RA13_RS06160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RA13_RS06170	COG2814	Major facilitator Superfamily
RA13_RS06190	COG1131	(ABC) transporter
RA13_RS06270	COG1595	DNA-templated transcription, initiation
RA13_RS06280	COG2508	Transcriptional regulator
RA13_RS06285	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RA13_RS06300	COG1801	Protein of unknown function DUF72
RA13_RS06305	COG0730	response to heat
RA13_RS06310	COG0737	Belongs to the 5'-nucleotidase family
RA13_RS06315	COG3377	Domain of unknown function (DUF1805)
RA13_RS06325	COG0739	heme binding
RA13_RS06340	COG4470	Protein conserved in bacteria
RA13_RS06345	COG2445	Protein of unknown function DUF86
RA13_RS06350	COG0647	UMP catabolic process
RA13_RS06355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RA13_RS06365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RA13_RS06370	COG0460	homoserine dehydrogenase
RA13_RS06375	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RA13_RS06380	COG0083	homoserine kinase activity
RA13_RS06385	COG4946	Tricorn protease homolog
RA13_RS06385	COG0823	Involved in the tonB-independent uptake of proteins
RA13_RS06385	COG1506	peptidase
RA13_RS06390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RA13_RS06395	COG4837	Protein of unknown function (DUF1462)
RA13_RS06400	COG3479	Phenolic acid decarboxylase
RA13_RS06405	COG1252	NADH dehydrogenase
RA13_RS06410	COG4844	belongs to the
RA13_RS06415	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RA13_RS06420	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RA13_RS06425	COG0316	Belongs to the HesB IscA family
RA13_RS06430	COG0516	GMP reductase activity
RA13_RS06445	COG1252	NADH dehydrogenase
RA13_RS06455	COG3584	3D domain protein
RA13_RS06460	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
RA13_RS06465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RA13_RS06470	COG2056	Na+-H+ antiporter family
RA13_RS06475	COG1268	BioY protein
RA13_RS06480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RA13_RS06495	COG2819	hydrolase of the alpha beta superfamily
RA13_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS06505	COG1169	isochorismate synthase
RA13_RS06515	COG3433	isochorismatase activity
RA13_RS06515	COG1535	isochorismatase
RA13_RS06520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS06525	COG3251	PFAM MbtH domain protein
RA13_RS06530	COG5634	Uncharacterized conserved protein (DUF2278)
RA13_RS06535	COG0686	Belongs to the AlaDH PNT family
RA13_RS06540	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RA13_RS06540	COG2508	Transcriptional regulator
RA13_RS06545	COG4842	Belongs to the WXG100 family
RA13_RS06550	COG5417	Belongs to the EsaB family
RA13_RS06555	COG4499	WXG100 protein secretion system (Wss), protein YukC
RA13_RS06560	COG1674	ftsk spoiiie
RA13_RS06560	COG0433	COG0433 Predicted ATPase
RA13_RS06565	COG1511	domain protein
RA13_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS06580	COG1418	mRNA catabolic process
RA13_RS06590	COG0628	permease
RA13_RS06605	COG5506	Protein of unknown function (DUF1694)
RA13_RS06610	COG1335	isochorismatase
RA13_RS06615	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RA13_RS06620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RA13_RS06635	COG0142	geranyltranstransferase activity
RA13_RS06645	COG4585	Histidine kinase
RA13_RS06650	COG2197	response regulator
RA13_RS06655	COG2050	protein possibly involved in aromatic compounds catabolism
RA13_RS06660	COG1320	monovalent cation:proton antiporter activity
RA13_RS06665	COG2212	antiporter activity
RA13_RS06670	COG1863	multisubunit Na H antiporter MnhE subunit
RA13_RS06675	COG0651	ATP synthesis coupled electron transport
RA13_RS06680	COG1006	Multisubunit Na H antiporter MnhC subunit
RA13_RS06685	COG2111	Na H antiporter
RA13_RS06700	COG3493	citrate carrier protein
RA13_RS06705	COG1079	Belongs to the binding-protein-dependent transport system permease family
RA13_RS06710	COG4603	Belongs to the binding-protein-dependent transport system permease family
RA13_RS06715	COG3845	ABC transporter
RA13_RS06720	COG1744	ABC transporter substrate-binding protein PnrA-like
RA13_RS06725	COG4565	transcriptional regulatory protein
RA13_RS06730	COG3290	protein histidine kinase activity
RA13_RS06740	COG3011	Protein conserved in bacteria
RA13_RS06745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RA13_RS06750	COG2814	Major facilitator Superfamily
RA13_RS06760	COG5018	Exonuclease
RA13_RS06770	COG2205	protein histidine kinase activity
RA13_RS06775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RA13_RS06785	COG2267	carboxylic ester hydrolase activity
RA13_RS06790	COG1522	sequence-specific DNA binding
RA13_RS06795	COG0436	Aminotransferase
RA13_RS06800	COG1098	S1 RNA binding domain
RA13_RS06805	COG2155	Conserved Protein
RA13_RS06810	COG1979	alcohol dehydrogenase
RA13_RS06815	COG1979	alcohol dehydrogenase
RA13_RS06825	COG0166	Belongs to the GPI family
RA13_RS06840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RA13_RS06855	COG2738	Putative neutral zinc metallopeptidase
RA13_RS06860	COG1253	flavin adenine dinucleotide binding
RA13_RS06870	COG0432	Pfam Uncharacterised protein family UPF0047
RA13_RS06875	COG2070	2-Nitropropane dioxygenase
RA13_RS06890	COG0840	transmembrane signaling receptor activity
RA13_RS06895	COG0840	transmembrane signaling receptor activity
RA13_RS06900	COG0840	transmembrane signaling receptor activity
RA13_RS06905	COG0840	transmembrane signaling receptor activity
RA13_RS06910	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS06910	COG3347	Dehydrogenase
RA13_RS06915	COG1349	DNA-binding transcription factor activity
RA13_RS06920	COG1070	Carbohydrate kinase
RA13_RS06925	COG3254	rhamnose metabolic process
RA13_RS06930	COG4806	L-rhamnose isomerase
RA13_RS06935	COG0693	protein deglycase activity
RA13_RS06940	COG0673	inositol 2-dehydrogenase activity
RA13_RS06945	COG0628	permease
RA13_RS07020	COG3677	Transposase
RA13_RS07030	COG0477	Major facilitator Superfamily
RA13_RS07035	COG1705	Flagellar rod assembly protein muramidase FlgJ
RA13_RS07045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RA13_RS07050	COG0569	domain protein
RA13_RS07060	COG1510	regulation of RNA biosynthetic process
RA13_RS07065	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS07070	COG1454	alcohol dehydrogenase
RA13_RS07080	COG2318	DinB family
RA13_RS07085	COG1585	Membrane protein implicated in regulation of membrane protease activity
RA13_RS07090	COG2268	Band 7 protein
RA13_RS07100	COG3764	Sortase (surface protein transpeptidase)
RA13_RS07105	COG3859	Proton-coupled thiamine transporter YuaJ
RA13_RS07230	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RA13_RS07235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RA13_RS07240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RA13_RS07245	COG0297	glycogen (starch) synthase activity
RA13_RS07250	COG0058	SHG alpha-glucan phosphorylase activity
RA13_RS07255	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
RA13_RS07260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RA13_RS07265	COG0438	transferase activity, transferring glycosyl groups
RA13_RS07270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RA13_RS07280	COG0438	transferase activity, transferring glycosyl groups
RA13_RS07285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS07295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RA13_RS07300	COG1169	isochorismate synthase
RA13_RS07305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RA13_RS07310	COG0596	Alpha beta hydrolase
RA13_RS07315	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RA13_RS07320	COG0318	PFAM AMP-dependent synthetase and ligase
RA13_RS07325	COG4948	Mandelate Racemase Muconate Lactonizing
RA13_RS07330	COG0803	Belongs to the bacterial solute-binding protein 9 family
RA13_RS07335	COG1121	(ABC) transporter
RA13_RS07340	COG1321	iron dependent repressor
RA13_RS07340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RA13_RS07345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RA13_RS07350	COG4305	rare lipoprotein A
RA13_RS07360	COG1294	oxidase, subunit
RA13_RS07365	COG1271	oxidase subunit
RA13_RS07375	COG0523	cobalamin synthesis protein
RA13_RS07380	COG0288	reversible hydration of carbon dioxide
RA13_RS07385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RA13_RS07405	COG0783	Belongs to the Dps family
RA13_RS07410	COG4824	toxin secretion phage lysis holin
RA13_RS07420	COG0494	nUDIX hydrolase
RA13_RS07425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RA13_RS07430	COG1116	anion transmembrane transporter activity
RA13_RS07435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RA13_RS07440	COG1506	peptidase
RA13_RS07450	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RA13_RS07460	COG0367	asparagine synthase
RA13_RS07465	COG1113	amino acid transport
RA13_RS07470	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RA13_RS07475	COG2267	carboxylic ester hydrolase activity
RA13_RS07485	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
RA13_RS07505	COG1725	Transcriptional regulator
RA13_RS07510	COG1131	(ABC) transporter
RA13_RS07520	COG1136	(ABC) transporter
RA13_RS07525	COG0577	efflux transmembrane transporter activity
RA13_RS07530	COG0745	RESPONSE REGULATOR receiver
RA13_RS07535	COG2205	protein histidine kinase activity
RA13_RS07540	COG1136	(ABC) transporter
RA13_RS07545	COG0577	efflux transmembrane transporter activity
RA13_RS07550	COG2433	Pfam Transposase IS66
RA13_RS07555	COG2814	Major facilitator Superfamily
RA13_RS07560	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS07560	COG2202	Pas domain
RA13_RS07570	COG0495	leucyl-tRNA aminoacylation
RA13_RS07575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RA13_RS07580	COG1653	transport
RA13_RS07585	COG1073	alpha beta
RA13_RS07590	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
RA13_RS07595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RA13_RS07600	COG0156	8-amino-7-oxononanoate synthase activity
RA13_RS07610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RA13_RS07615	COG2124	cytochrome p450
RA13_RS07620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS07625	COG0395	ABC-type sugar transport system, permease component
RA13_RS07630	COG1653	transport
RA13_RS07635	COG2207	Transcriptional regulator
RA13_RS07640	COG4209	transmembrane transport
RA13_RS07645	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RA13_RS07650	COG1653	transport
RA13_RS07655	COG0673	inositol 2-dehydrogenase activity
RA13_RS07660	COG5578	integral membrane protein
RA13_RS07670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
RA13_RS07675	COG2081	HI0933 family
RA13_RS07680	COG2244	polysaccharide biosynthetic process
RA13_RS07685	COG1187	pseudouridine synthase activity
RA13_RS07690	COG1349	DNA-binding transcription factor activity
RA13_RS07695	COG2252	PERMEase
RA13_RS07700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RA13_RS07705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RA13_RS07710	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
RA13_RS07720	COG1597	lipid kinase activity
RA13_RS07725	COG1523	belongs to the glycosyl hydrolase 13 family
RA13_RS07730	COG0510	thiamine kinase activity
RA13_RS07740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RA13_RS07745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RA13_RS07750	COG0281	malic enzyme
RA13_RS07755	COG5584	Small secreted protein
RA13_RS07770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS07775	COG4848	Belongs to the UPF0354 family
RA13_RS07780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RA13_RS07785	COG1674	ftsk spoiiie
RA13_RS07795	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RA13_RS07800	COG4980	gas vesicle protein
RA13_RS07805	COG3118	belongs to the thioredoxin family
RA13_RS07810	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RA13_RS07810	COG1605	Chorismate mutase
RA13_RS07815	COG1609	Transcriptional regulator
RA13_RS07820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RA13_RS07825	COG1360	Flagellar Motor Protein
RA13_RS07830	COG0123	including yeast histone deacetylase and acetoin utilization protein
RA13_RS07835	COG0517	IMP dehydrogenase activity
RA13_RS07840	COG0454	-acetyltransferase
RA13_RS07845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RA13_RS07850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RA13_RS07855	COG0583	DNA-binding transcription factor activity
RA13_RS07865	COG0400	carboxylic ester hydrolase activity
RA13_RS07875	COG0346	lactoylglutathione lyase activity
RA13_RS07880	COG2259	Doxx family
RA13_RS07900	COG1335	isochorismatase
RA13_RS07925	COG2203	Gaf domain
RA13_RS07925	COG2199	diguanylate cyclase activity
RA13_RS07930	COG1956	GAF domain-containing protein
RA13_RS07935	COG1309	transcriptional regulator
RA13_RS07940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RA13_RS07945	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
RA13_RS07950	COG1114	Component of the transport system for branched-chain amino acids
RA13_RS07955	COG1104	cysteine desulfurase activity
RA13_RS07960	COG0301	tRNA thio-modification
RA13_RS07970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RA13_RS07975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
RA13_RS07980	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RA13_RS07985	COG0616	signal peptide processing
RA13_RS07990	COG1714	RDD family
RA13_RS08000	COG3874	Sporulation protein YtfJ
RA13_RS08005	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
RA13_RS08010	COG0827	DNA restriction-modification system
RA13_RS08020	COG0521	Mo-molybdopterin cofactor biosynthetic process
RA13_RS08025	COG0137	argininosuccinate synthase activity
RA13_RS08030	COG0165	Argininosuccinate lyase
RA13_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS08040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RA13_RS08045	COG4109	DRTGG domain
RA13_RS08055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RA13_RS08080	COG0281	malic enzyme
RA13_RS08085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RA13_RS08090	COG0825	malonyl-CoA metabolic process
RA13_RS08100	COG0469	pyruvate kinase activity
RA13_RS08105	COG3030	protein affecting phage T7 exclusion by the F plasmid
RA13_RS08110	COG0628	permease
RA13_RS08115	COG2707	UPF0756 membrane protein
RA13_RS08120	COG0372	Belongs to the citrate synthase family
RA13_RS08125	COG0538	isocitrate dehydrogenase activity
RA13_RS08135	COG0745	RESPONSE REGULATOR receiver
RA13_RS08140	COG5002	protein histidine kinase activity
RA13_RS08145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RA13_RS08145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RA13_RS08150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RA13_RS08155	COG1971	Probably functions as a manganese efflux pump
RA13_RS08160	COG0237	dephospho-CoA kinase activity
RA13_RS08165	COG0656	L-ascorbic acid biosynthetic process
RA13_RS08170	COG2814	Major facilitator Superfamily
RA13_RS08175	COG1733	regulation of RNA biosynthetic process
RA13_RS08180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RA13_RS08185	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RA13_RS08190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RA13_RS08195	COG3611	Membrane attachment protein
RA13_RS08200	COG1484	DNA-dependent DNA replication
RA13_RS08205	COG0398	Pfam SNARE associated Golgi protein
RA13_RS08215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RA13_RS08220	COG1011	Hydrolase
RA13_RS08225	COG3275	phosphorelay sensor kinase activity
RA13_RS08230	COG3279	Response regulator of the LytR AlgR family
RA13_RS08240	COG1346	cytolysis
RA13_RS08260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RA13_RS08265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RA13_RS08270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RA13_RS08275	COG3326	Membrane
RA13_RS08285	COG1363	Peptidase, m42
RA13_RS08290	COG3507	Belongs to the glycosyl hydrolase 43 family
RA13_RS08315	COG2160	L-arabinose isomerase activity
RA13_RS08320	COG1069	ribulokinase activity
RA13_RS08325	COG0235	Class ii aldolase
RA13_RS08330	COG0647	UMP catabolic process
RA13_RS08335	COG0371	Dehydrogenase
RA13_RS08340	COG1653	transport
RA13_RS08345	COG1175	transmembrane transport
RA13_RS08350	COG0395	ABC-type sugar transport system, permease component
RA13_RS08355	COG3534	alpha-L-arabinofuranosidase
RA13_RS08360	COG1966	Carbon starvation protein
RA13_RS08365	COG0346	lactoylglutathione lyase activity
RA13_RS08370	COG0247	lactate metabolic process
RA13_RS08375	COG0277	FAD linked oxidase domain protein
RA13_RS08380	COG3835	regulator
RA13_RS08390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RA13_RS08395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RA13_RS08400	COG0072	phenylalanine-tRNA ligase activity
RA13_RS08400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RA13_RS08410	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
RA13_RS08415	COG1286	toxin biosynthetic process
RA13_RS08420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RA13_RS08420	COG1796	DNA polymerase
RA13_RS08425	COG1193	negative regulation of DNA recombination
RA13_RS08430	COG3766	membrane
RA13_RS08435	COG0318	PFAM AMP-dependent synthetase and ligase
RA13_RS08440	COG1309	transcriptional regulator
RA13_RS08445	COG1024	Enoyl-CoA hydratase
RA13_RS08450	COG2086	electron transfer activity
RA13_RS08455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RA13_RS08460	COG3534	alpha-L-arabinofuranosidase
RA13_RS08465	COG3118	belongs to the thioredoxin family
RA13_RS08470	COG0322	excinuclease ABC activity
RA13_RS08475	COG0527	aspartate kinase activity
RA13_RS08480	COG1719	4-vinyl reductase, 4VR
RA13_RS08485	COG2009	succinate dehydrogenase
RA13_RS08490	COG1053	succinate dehydrogenase
RA13_RS08500	COG0824	Thioesterase
RA13_RS08505	COG2197	response regulator
RA13_RS08510	COG1846	Transcriptional regulator
RA13_RS08515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RA13_RS08520	COG5401	PFAM Sporulation and spore germination
RA13_RS08525	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RA13_RS08530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RA13_RS08535	COG0622	Phosphoesterase
RA13_RS08545	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
RA13_RS08550	COG0454	-acetyltransferase
RA13_RS08555	COG0028	Belongs to the TPP enzyme family
RA13_RS08560	COG0440	acetolactate synthase activity
RA13_RS08565	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RA13_RS08570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RA13_RS08575	COG0473	3-isopropylmalate dehydrogenase activity
RA13_RS08580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RA13_RS08585	COG0066	3-isopropylmalate dehydratase activity
RA13_RS08590	COG1477	protein flavinylation
RA13_RS08590	COG0457	Tetratricopeptide repeat
RA13_RS08595	COG0544	peptidyl-prolyl cis-trans isomerase activity
RA13_RS08610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RA13_RS08625	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RA13_RS08630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RA13_RS08640	COG1587	Uroporphyrinogen-III synthase
RA13_RS08645	COG0113	porphobilinogen synthase activity
RA13_RS08650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RA13_RS08655	COG1388	LysM domain
RA13_RS08660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RA13_RS08670	COG0525	valine-tRNA ligase activity
RA13_RS08675	COG0285	dihydrofolate synthase activity
RA13_RS08680	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RA13_RS08690	COG0424	maF-like protein
RA13_RS08695	COG2003	Belongs to the UPF0758 family
RA13_RS08700	COG1077	Cell shape determining protein MreB Mrl
RA13_RS08710	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RA13_RS08715	COG0850	regulation of cytokinetic process
RA13_RS08720	COG2894	cell division
RA13_RS08725	COG0739	heme binding
RA13_RS08730	COG1994	Peptidase M50
RA13_RS08735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RA13_RS08740	COG2868	ribosomal protein
RA13_RS08745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RA13_RS08750	COG3290	protein histidine kinase activity
RA13_RS08755	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RA13_RS08765	COG0077	Prephenate dehydratase
RA13_RS08770	COG1827	regulation of RNA biosynthetic process
RA13_RS08775	COG1104	cysteine desulfurase activity
RA13_RS08780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RA13_RS08785	COG0157	Belongs to the NadC ModD family
RA13_RS08790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RA13_RS08795	COG1388	LysM domain
RA13_RS08810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RA13_RS08815	COG1447	Phosphotransferase system cellobiose-specific component IIA
RA13_RS08820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
RA13_RS08825	COG1486	melibiose metabolic process
RA13_RS08830	COG2188	Transcriptional regulator
RA13_RS08835	COG3394	polysaccharide catabolic process
RA13_RS08855	COG0217	transcriptional regulatory protein
RA13_RS08870	COG2112	serine threonine protein kinase
RA13_RS08875	COG2814	Major facilitator Superfamily
RA13_RS08885	COG0632	four-way junction helicase activity
RA13_RS08890	COG2255	four-way junction helicase activity
RA13_RS08900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RA13_RS08910	COG1862	Preprotein translocase
RA13_RS08920	COG2323	membrane
RA13_RS08925	COG2244	polysaccharide biosynthetic process
RA13_RS08935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RA13_RS08935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RA13_RS08940	COG0490	domain, Protein
RA13_RS08945	COG5416	Lipopolysaccharide assembly protein A domain
RA13_RS08950	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RA13_RS08950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RA13_RS08965	COG1490	D-aminoacyl-tRNA deacylase activity
RA13_RS08970	COG3103	Sh3 type 3 domain protein
RA13_RS08970	COG4991	sh3 domain protein
RA13_RS08970	COG0860	N-Acetylmuramoyl-L-alanine amidase
RA13_RS08980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RA13_RS08990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RA13_RS08995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RA13_RS09000	COG1959	2 iron, 2 sulfur cluster binding
RA13_RS09005	COG1104	cysteine desulfurase activity
RA13_RS09015	COG0457	Tetratricopeptide repeat
RA13_RS09020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RA13_RS09025	COG3881	PFAM PRC-barrel domain
RA13_RS09040	COG0765	amino acid transport
RA13_RS09045	COG0765	amino acid transport
RA13_RS09050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RA13_RS09055	COG1126	abc transporter atp-binding protein
RA13_RS09060	COG0628	permease
RA13_RS09065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RA13_RS09070	COG4472	Bacterial protein of unknown function (DUF965)
RA13_RS09075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RA13_RS09080	COG3906	Belongs to the UPF0473 family
RA13_RS09085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RA13_RS09090	COG4122	O-methyltransferase activity
RA13_RS09095	COG0826	peptidase U32
RA13_RS09100	COG0826	peptidase U32
RA13_RS09105	COG0572	uridine kinase
RA13_RS09110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RA13_RS09130	COG2226	methyltransferase
RA13_RS09135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RA13_RS09140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RA13_RS09145	COG0626	cystathionine gamma-synthase activity
RA13_RS09155	COG2427	Protein of unknown function (DUF1641)
RA13_RS09160	COG3383	formate dehydrogenase (NAD+) activity
RA13_RS09165	COG5609	conserved protein (DUF2294)
RA13_RS09175	COG2116	formate transmembrane transporter activity
RA13_RS09190	COG2226	methyltransferase
RA13_RS09195	COG1309	transcriptional regulator
RA13_RS09200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RA13_RS09200	COG2124	cytochrome p450
RA13_RS09205	COG2176	DNA-directed DNA polymerase activity
RA13_RS09210	COG2814	Major facilitator Superfamily
RA13_RS09215	COG0583	DNA-binding transcription factor activity
RA13_RS09230	COG3443	Belongs to the bacterial solute-binding protein 9 family
RA13_RS09245	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RA13_RS09255	COG0583	DNA-binding transcription factor activity
RA13_RS09270	COG1725	Transcriptional regulator
RA13_RS09295	COG2732	(Barnase) inhibitor
RA13_RS09300	COG1309	transcriptional regulator
RA13_RS09340	COG1733	regulation of RNA biosynthetic process
RA13_RS09345	COG2085	NADP oxidoreductase coenzyme F420-dependent
RA13_RS09365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RA13_RS09410	COG0398	Pfam SNARE associated Golgi protein
RA13_RS09425	COG2755	lipolytic protein G-D-S-L family
RA13_RS09435	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RA13_RS09440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RA13_RS09445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RA13_RS09450	COG1534	Rna-binding protein
RA13_RS09455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RA13_RS09460	COG1713	HD superfamily hydrolase involved in NAD metabolism
RA13_RS09465	COG0799	negative regulation of ribosome biogenesis
RA13_RS09470	COG2226	methyltransferase
RA13_RS09475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RA13_RS09480	COG1596	polysaccharide export
RA13_RS09480	COG1555	photosystem II stabilization
RA13_RS09485	COG2131	deaminase
RA13_RS09490	COG0658	competence protein
RA13_RS09490	COG2333	competence protein COMEC
RA13_RS09500	COG1466	dna polymerase III delta subunit
RA13_RS09515	COG0860	N-Acetylmuramoyl-L-alanine amidase
RA13_RS09525	COG0481	GTPase activity
RA13_RS09530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RA13_RS09535	COG1420	regulation of RNA biosynthetic process
RA13_RS09540	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RA13_RS09560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RA13_RS09565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RA13_RS09570	COG1283	sodium-dependent phosphate transmembrane transporter activity
RA13_RS09580	COG1610	YqeY-like protein
RA13_RS09590	COG4864	UPF0365 protein
RA13_RS09625	COG0561	phosphatase activity
RA13_RS09630	COG1702	phosphate starvation-inducible protein PhoH
RA13_RS09635	COG1480	7TM receptor with intracellular HD hydrolase
RA13_RS09645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RA13_RS09650	COG0295	cytidine deaminase activity
RA13_RS09655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RA13_RS09665	COG1381	Involved in DNA repair and RecF pathway recombination
RA13_RS09670	COG0752	glycyl-tRNA synthetase alpha subunit
RA13_RS09675	COG0751	glycine-tRNA ligase activity
RA13_RS09680	COG0517	IMP dehydrogenase activity
RA13_RS09685	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RA13_RS09690	COG1671	Belongs to the UPF0178 family
RA13_RS09695	COG0358	DNA primase activity
RA13_RS09700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RA13_RS09705	COG2010	Cytochrome c
RA13_RS09710	COG2384	SAM-dependent methyltransferase
RA13_RS09715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RA13_RS09720	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RA13_RS09730	COG0513	Belongs to the DEAD box helicase family
RA13_RS09735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
RA13_RS09745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS09750	COG0735	belongs to the Fur family
RA13_RS09755	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
RA13_RS09760	COG4709	membrane
RA13_RS09770	COG1388	LysM domain
RA13_RS09775	COG5521	maltodextrose utilization protein MalA
RA13_RS09780	COG2839	Protein conserved in bacteria
RA13_RS09785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RA13_RS09790	COG0477	Major facilitator Superfamily
RA13_RS09795	COG0768	penicillin binding
RA13_RS09800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RA13_RS09805	COG0573	inorganic phosphate transmembrane transporter activity
RA13_RS09810	COG0581	inorganic phosphate transmembrane transporter activity
RA13_RS09815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RA13_RS09820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RA13_RS09825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RA13_RS09840	COG0438	transferase activity, transferring glycosyl groups
RA13_RS09850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RA13_RS09860	COG0705	Rhomboid family
RA13_RS09860	COG0457	Tetratricopeptide repeat
RA13_RS09865	COG4483	Protein conserved in bacteria
RA13_RS09870	COG1940	carbohydrate kinase activity
RA13_RS09875	COG1368	sulfuric ester hydrolase activity
RA13_RS09880	COG2866	Carboxypeptidase
RA13_RS09890	COG0011	TIGRFAM Protein of
RA13_RS09900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RA13_RS09910	COG1393	Belongs to the ArsC family
RA13_RS09920	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS09925	COG1253	flavin adenine dinucleotide binding
RA13_RS09930	COG0598	Magnesium transport protein CorA
RA13_RS09935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RA13_RS09940	COG1459	type II secretion system
RA13_RS09945	COG4537	Required for transformation and DNA binding
RA13_RS09950	COG4970	Tfp pilus assembly protein FimT
RA13_RS09960	COG4940	Competence protein ComGF
RA13_RS09985	COG0681	Belongs to the peptidase S26 family
RA13_RS09995	COG1396	sequence-specific DNA binding
RA13_RS10010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RA13_RS10015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RA13_RS10020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RA13_RS10025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RA13_RS10030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RA13_RS10035	COG0095	Lipoate-protein ligase
RA13_RS10040	COG1321	iron dependent repressor
RA13_RS10055	COG3872	metal-dependent enzyme
RA13_RS10065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RA13_RS10070	COG0006	proline dipeptidase activity
RA13_RS10075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RA13_RS10085	COG3854	ATPases associated with a variety of cellular activities
RA13_RS10125	COG0511	ligase activity, forming carbon-carbon bonds
RA13_RS10130	COG0439	Biotin carboxylase
RA13_RS10135	COG1302	Protein conserved in bacteria
RA13_RS10140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RA13_RS10145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RA13_RS10150	COG1570	exodeoxyribonuclease VII activity
RA13_RS10155	COG1722	exodeoxyribonuclease VII activity
RA13_RS10160	COG0142	geranyltranstransferase activity
RA13_RS10165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RA13_RS10170	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RA13_RS10175	COG1438	arginine binding
RA13_RS10180	COG0497	DNA recombination
RA13_RS10185	COG0750	zinc metalloprotease
RA13_RS10190	COG0745	RESPONSE REGULATOR receiver
RA13_RS10200	COG1902	pentaerythritol trinitrate reductase activity
RA13_RS10210	COG0860	N-Acetylmuramoyl-L-alanine amidase
RA13_RS10215	COG0584	glycerophosphoryl diester phosphodiesterase
RA13_RS10220	COG0183	Belongs to the thiolase family
RA13_RS10225	COG1250	3-hydroxyacyl-CoA dehydrogenase
RA13_RS10230	COG1960	acyl-CoA dehydrogenase activity
RA13_RS10235	COG0372	Belongs to the citrate synthase family
RA13_RS10240	COG2079	MmgE PrpD family protein
RA13_RS10245	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RA13_RS10260	COG0280	phosphate acetyltransferase
RA13_RS10270	COG3426	butyrate kinase activity
RA13_RS10280	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RA13_RS10285	COG0022	dehydrogenase e1 component
RA13_RS10290	COG0508	dehydrogenase complex catalyzes the overall conversion of
RA13_RS10300	COG1597	lipid kinase activity
RA13_RS10310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RA13_RS10315	COG0765	amino acid transport
RA13_RS10320	COG1126	abc transporter atp-binding protein
RA13_RS10325	COG4129	membrane
RA13_RS10330	COG1376	ErfK ybiS ycfS ynhG family protein
RA13_RS10335	COG0346	lactoylglutathione lyase activity
RA13_RS10340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RA13_RS10345	COG2195	Cleaves the N-terminal amino acid of tripeptides
RA13_RS10350	COG3361	conserved protein (COG2071)
RA13_RS10355	COG0706	membrane insertase activity
RA13_RS10365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RA13_RS10370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RA13_RS10375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RA13_RS10390	COG0596	Alpha beta hydrolase
RA13_RS10395	COG1902	pentaerythritol trinitrate reductase activity
RA13_RS10400	COG4187	Peptidase family M20/M25/M40
RA13_RS10405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RA13_RS10410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RA13_RS10415	COG0300	oxidoreductase activity
RA13_RS10420	COG3048	D-serine ammonia-lyase activity
RA13_RS10425	COG1072	(Pantothenic acid kinase))
RA13_RS10450	COG0628	permease
RA13_RS10460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RA13_RS10470	COG0456	acetyltransferase
RA13_RS10475	COG2329	Antibiotic biosynthesis monooxygenase
RA13_RS10480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RA13_RS10480	COG0456	acetyltransferase
RA13_RS10485	COG4918	Iron-sulphur cluster biosynthesis
RA13_RS10495	COG1073	alpha beta
RA13_RS10505	COG0667	Aldo Keto reductase
RA13_RS10515	COG0494	nUDIX hydrolase
RA13_RS10520	COG1379	DNA repair
RA13_RS10525	COG1396	sequence-specific DNA binding
RA13_RS10530	COG0252	asparaginase activity
RA13_RS10535	COG1027	Aspartate ammonia-lyase
RA13_RS10540	COG1757	Na H antiporter
RA13_RS10545	COG0281	malic enzyme
RA13_RS10555	COG1300	Membrane
RA13_RS10560	COG0735	belongs to the Fur family
RA13_RS10570	COG4974	Belongs to the 'phage' integrase family
RA13_RS10575	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RA13_RS10580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RA13_RS10585	COG1686	Belongs to the peptidase S11 family
RA13_RS10590	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS10595	COG2172	sigma factor antagonist activity
RA13_RS10600	COG1191	sigma factor activity
RA13_RS10620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RA13_RS10635	COG0697	spore germination
RA13_RS10640	COG0019	diaminopimelate decarboxylase activity
RA13_RS10645	COG4086	secreted protein
RA13_RS10650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RA13_RS10660	COG3420	alginic acid biosynthetic process
RA13_RS10680	COG3833	ABC-type maltose transport systems, permease component
RA13_RS10685	COG1175	transmembrane transport
RA13_RS10690	COG2182	Extracellular solute-binding protein
RA13_RS10710	COG0673	inositol 2-dehydrogenase activity
RA13_RS10720	COG1278	Cold shock
RA13_RS10725	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
RA13_RS10730	COG0681	Belongs to the peptidase S26 family
RA13_RS10740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RA13_RS10740	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RA13_RS10745	COG0307	riboflavin synthase, alpha
RA13_RS10750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RA13_RS10750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RA13_RS10755	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RA13_RS10760	COG0456	acetyltransferase
RA13_RS10765	COG1547	Domain of unknown function (DUF309)
RA13_RS10775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
RA13_RS10780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RA13_RS10790	COG1686	Belongs to the peptidase S11 family
RA13_RS10795	COG2715	membrane protein required for spore maturation
RA13_RS10800	COG0700	Nucleoside recognition
RA13_RS10805	COG1187	pseudouridine synthase activity
RA13_RS10810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS10815	COG1333	cytochrome c biogenesis protein
RA13_RS10820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RA13_RS10825	COG0745	RESPONSE REGULATOR receiver
RA13_RS10830	COG5002	protein histidine kinase activity
RA13_RS10835	COG1595	DNA-templated transcription, initiation
RA13_RS10845	COG0710	3-dehydroquinate dehydratase activity
RA13_RS10850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RA13_RS10855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
RA13_RS10860	COG1141	Ferredoxin
RA13_RS10865	COG4955	Helix-turn-helix domain
RA13_RS10870	COG0514	ATP-dependent DNA helicase (RecQ)
RA13_RS10875	COG1266	CAAX protease self-immunity
RA13_RS10880	COG1388	LysM domain
RA13_RS10890	COG1408	metallophosphoesterase
RA13_RS10895	COG4862	establishment of competence for transformation
RA13_RS10900	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RA13_RS10910	COG2339	peptidase activity
RA13_RS10915	COG3773	Cell wall hydrolase
RA13_RS10915	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS10920	COG2959	enzyme of heme biosynthesis
RA13_RS10925	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
RA13_RS10935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RA13_RS10940	COG0539	negative regulation of cytoplasmic translation
RA13_RS10945	COG1304	FMN binding
RA13_RS10970	COG1160	GTP binding
RA13_RS10975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RA13_RS10990	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RA13_RS10995	COG0776	regulation of translation
RA13_RS11000	COG0302	gtp cyclohydrolase
RA13_RS11010	COG0142	geranyltranstransferase activity
RA13_RS11020	COG0142	geranyltranstransferase activity
RA13_RS11025	COG0105	UTP biosynthetic process
RA13_RS11030	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RA13_RS11045	COG4401	Chorismate mutase type I
RA13_RS11050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RA13_RS11075	COG0159	tryptophan synthase activity
RA13_RS11080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RA13_RS11085	COG0287	Prephenate dehydrogenase
RA13_RS11090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RA13_RS11095	COG0457	Tetratricopeptide repeat
RA13_RS11100	COG5582	Belongs to the UPF0302 family
RA13_RS11110	COG0723	plastoquinol--plastocyanin reductase activity
RA13_RS11115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RA13_RS11120	COG2010	Cytochrome c
RA13_RS11120	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RA13_RS11125	COG4347	Protein of unknown function (DUF1405)
RA13_RS11135	COG2140	Oxalate decarboxylase
RA13_RS11140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS11145	COG1694	Mazg nucleotide pyrophosphohydrolase
RA13_RS11160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RA13_RS11165	COG0438	transferase activity, transferring glycosyl groups
RA13_RS11170	COG0617	tRNA 3'-terminal CCA addition
RA13_RS11175	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
RA13_RS11175	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
RA13_RS11180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RA13_RS11185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RA13_RS11190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RA13_RS11195	COG1199	ATP-dependent helicase activity
RA13_RS11195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RA13_RS11205	COG5353	protein conserved in bacteria
RA13_RS11210	COG0436	Aminotransferase
RA13_RS11215	COG0017	Asparaginyl-tRNA synthetase
RA13_RS11220	COG3935	DnaD domain protein
RA13_RS11225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RA13_RS11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RA13_RS11235	COG4499	WXG100 protein secretion system (Wss), protein YukC
RA13_RS11240	COG3331	DNA recombination
RA13_RS11275	COG0071	Belongs to the small heat shock protein (HSP20) family
RA13_RS11280	COG2190	(PTS) system
RA13_RS11290	COG3359	exonuclease
RA13_RS11320	COG0116	Belongs to the methyltransferase superfamily
RA13_RS11335	COG1199	ATP-dependent helicase activity
RA13_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS11345	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
RA13_RS11350	COG1609	Transcriptional regulator
RA13_RS11355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RA13_RS11360	COG0800	Aldolase
RA13_RS11370	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
RA13_RS11375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RA13_RS11380	COG2233	PERMEase
RA13_RS11385	COG3424	synthase
RA13_RS11390	COG1755	Isoprenylcysteine carboxyl methyltransferase
RA13_RS11400	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
RA13_RS11415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RA13_RS11425	COG0328	RNA-DNA hybrid ribonuclease activity
RA13_RS11430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RA13_RS11435	COG0328	RNA-DNA hybrid ribonuclease activity
RA13_RS11455	COG1278	Cold shock
RA13_RS11460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RA13_RS11465	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RA13_RS11475	COG1418	mRNA catabolic process
RA13_RS11480	COG1413	lyase activity
RA13_RS11495	COG2136	Putative SAM-dependent methyltransferase
RA13_RS11495	COG2521	methyltransferase
RA13_RS11505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RA13_RS11515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
RA13_RS11520	COG0204	Acyl-transferase
RA13_RS11525	COG1272	protein, Hemolysin III
RA13_RS11530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RA13_RS11535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RA13_RS11545	COG1999	signal sequence binding
RA13_RS11550	COG2755	lipolytic protein G-D-S-L family
RA13_RS11555	COG4698	Protein conserved in bacteria
RA13_RS11565	COG0534	Mate efflux family protein
RA13_RS11570	COG1846	Transcriptional regulator
RA13_RS11575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RA13_RS11600	COG2207	Transcriptional regulator
RA13_RS11600	COG3708	Transcriptional regulator
RA13_RS11605	COG5444	nuclease activity
RA13_RS11615	COG3655	Transcriptional regulator
RA13_RS11625	COG3397	chitin binding
RA13_RS11630	COG0366	Alpha amylase catalytic
RA13_RS11645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RA13_RS11650	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
RA13_RS11655	COG4641	Protein conserved in bacteria
RA13_RS11670	COG0463	Glycosyl transferase, family 2
RA13_RS11675	COG0456	acetyltransferase
RA13_RS11685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RA13_RS11690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RA13_RS11695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RA13_RS11700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RA13_RS11705	COG0456	acetyltransferase
RA13_RS11710	COG1509	lysine 2,3-aminomutase activity
RA13_RS11735	COG0671	phosphoesterase, PA-phosphatase related
RA13_RS11750	COG0813	purine-nucleoside phosphorylase activity
RA13_RS11755	COG1876	peptidase activity
RA13_RS11765	COG2226	methyltransferase
RA13_RS11770	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS11770	COG0793	Belongs to the peptidase S41A family
RA13_RS11775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS11785	COG0346	lactoylglutathione lyase activity
RA13_RS11790	COG0400	carboxylic ester hydrolase activity
RA13_RS11795	COG0778	Nitroreductase
RA13_RS11800	COG1733	regulation of RNA biosynthetic process
RA13_RS11805	COG1942	4-Oxalocrotonate Tautomerase
RA13_RS11825	COG2962	Rard protein
RA13_RS11835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RA13_RS11840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RA13_RS11845	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS11850	COG0582	viral genome integration into host DNA
RA13_RS11905	COG0305	Participates in initiation and elongation during chromosome replication
RA13_RS11925	COG1595	DNA-templated transcription, initiation
RA13_RS11970	COG4626	Terminase
RA13_RS11970	COG1802	Transcriptional regulator
RA13_RS12050	COG1705	Flagellar rod assembly protein muramidase FlgJ
RA13_RS12055	COG5434	Belongs to the glycosyl hydrolase 28 family
RA13_RS12075	COG4824	toxin secretion phage lysis holin
RA13_RS12080	COG5632	N-Acetylmuramoyl-L-alanine amidase
RA13_RS12080	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS12100	COG5444	nuclease activity
RA13_RS12125	COG0534	Mate efflux family protein
RA13_RS12130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RA13_RS12140	COG0791	NLP P60 protein
RA13_RS12140	COG1388	LysM domain
RA13_RS12145	COG2032	superoxide dismutase activity
RA13_RS12150	COG0714	Associated with various cellular activities
RA13_RS12155	COG4548	von Willebrand factor, type A
RA13_RS12160	COG0567	Dehydrogenase, E1 component
RA13_RS12165	COG0508	dehydrogenase complex catalyzes the overall conversion of
RA13_RS12170	COG0385	Bile acid
RA13_RS12175	COG0733	neurotransmitter:sodium symporter activity
RA13_RS12180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RA13_RS12185	COG1657	PFAM Prenyltransferase squalene oxidase
RA13_RS12190	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS12210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RA13_RS12215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RA13_RS12225	COG0514	ATP-dependent DNA helicase (RecQ)
RA13_RS12230	COG3584	3D domain protein
RA13_RS12230	COG1388	LysM domain
RA13_RS12235	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS12245	COG2197	response regulator
RA13_RS12250	COG4585	Histidine kinase
RA13_RS12255	COG3239	Fatty acid desaturase
RA13_RS12270	COG2322	membrane
RA13_RS12275	COG0741	lytic transglycosylase activity
RA13_RS12280	COG0640	Transcriptional regulator
RA13_RS12295	COG3708	Transcriptional regulator
RA13_RS12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RA13_RS12305	COG1309	transcriptional regulator
RA13_RS12310	COG2207	Transcriptional regulator
RA13_RS12310	COG0662	Cupin 2, conserved barrel domain protein
RA13_RS12315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RA13_RS12320	COG1309	transcriptional regulator
RA13_RS12340	COG0243	molybdopterin cofactor binding
RA13_RS12345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RA13_RS12350	COG1070	Carbohydrate kinase
RA13_RS12355	COG2814	Major facilitator Superfamily
RA13_RS12360	COG2318	DinB family
RA13_RS12365	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
RA13_RS12370	COG0300	oxidoreductase activity
RA13_RS12380	COG0693	protein deglycase activity
RA13_RS12415	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RA13_RS12420	COG0583	DNA-binding transcription factor activity
RA13_RS12425	COG0070	glutamate synthase
RA13_RS12425	COG0069	glutamate synthase activity
RA13_RS12425	COG0067	glutamate synthase
RA13_RS12435	COG0604	alcohol dehydrogenase
RA13_RS12445	COG0405	Gamma-glutamyltransferase
RA13_RS12450	COG0166	Belongs to the GPI family
RA13_RS12455	COG0582	viral genome integration into host DNA
RA13_RS12470	COG4824	toxin secretion phage lysis holin
RA13_RS12485	COG0457	Tetratricopeptide repeat
RA13_RS12505	COG2017	converts alpha-aldose to the beta-anomer
RA13_RS12510	COG2027	D-alanyl-D-alanine carboxypeptidase
RA13_RS12515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RA13_RS12515	COG1017	nitric oxide dioxygenase activity
RA13_RS12520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS12525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS12530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS12540	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RA13_RS12540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS12550	COG1649	PFAM Uncharacterised BCR, COG1649
RA13_RS12555	COG1960	acyl-CoA dehydrogenase activity
RA13_RS12560	COG0318	PFAM AMP-dependent synthetase and ligase
RA13_RS12565	COG0439	Biotin carboxylase
RA13_RS12570	COG0511	ligase activity, forming carbon-carbon bonds
RA13_RS12580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RA13_RS12585	COG2404	hydrolase activity, acting on ester bonds
RA13_RS12590	COG0586	Pfam SNARE associated Golgi protein
RA13_RS12595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RA13_RS12600	COG2246	polysaccharide biosynthetic process
RA13_RS12620	COG1115	amino acid carrier protein
RA13_RS12630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RA13_RS12635	COG0187	DNA topoisomerase II activity
RA13_RS12640	COG1832	CoA-binding protein
RA13_RS12645	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RA13_RS12650	COG4841	protein insertion into membrane
RA13_RS12660	COG0824	Thioesterase
RA13_RS12680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS12685	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RA13_RS12700	COG0071	Belongs to the small heat shock protein (HSP20) family
RA13_RS12710	COG4846	Membrane protein involved in cytochrome C biogenesis
RA13_RS12715	COG2201	protein-glutamate methylesterase activity
RA13_RS12720	COG0785	Cytochrome C biogenesis protein
RA13_RS12730	COG3763	UPF0154 protein
RA13_RS12740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RA13_RS12745	COG4224	UPF0291 protein
RA13_RS12750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
RA13_RS12755	COG1388	LysM domain
RA13_RS12760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RA13_RS12770	COG5577	PFAM Coat F domain
RA13_RS12790	COG4195	phage-related replication protein
RA13_RS12810	COG3619	membrane
RA13_RS12860	COG1131	(ABC) transporter
RA13_RS12875	COG0457	Tetratricopeptide repeat
RA13_RS12890	COG2135	peptidase activity
RA13_RS12905	COG2030	dehydratase
RA13_RS12910	COG0789	Transcriptional regulator
RA13_RS12910	COG4978	Transcriptional regulator
RA13_RS12915	COG0456	acetyltransferase
RA13_RS12940	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS12950	COG5553	Cysteine dioxygenase type I
RA13_RS12970	COG0135	phosphoribosylanthranilate isomerase activity
RA13_RS13010	COG2367	Beta-lactamase
RA13_RS13050	COG1011	Hydrolase
RA13_RS13060	COG0657	acetylesterase activity
RA13_RS13080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS13085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RA13_RS13115	COG3118	belongs to the thioredoxin family
RA13_RS13125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS13135	COG0509	glycine decarboxylation via glycine cleavage system
RA13_RS13145	COG1309	transcriptional regulator
RA13_RS13150	COG1609	Transcriptional regulator
RA13_RS13160	COG1175	transmembrane transport
RA13_RS13195	COG3391	amine dehydrogenase activity
RA13_RS13265	COG2273	Hydrolase Family 16
RA13_RS13315	COG5444	nuclease activity
RA13_RS13320	COG1136	(ABC) transporter
RA13_RS13350	COG4282	regulation of fungal-type cell wall biogenesis
RA13_RS13370	COG0456	acetyltransferase
RA13_RS13455	COG0174	glutamine synthetase
RA13_RS13460	COG0789	Transcriptional regulator
RA13_RS13465	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RA13_RS13470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RA13_RS13485	COG3331	DNA recombination
RA13_RS13505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RA13_RS13555	COG4112	unkown
RA13_RS13570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS13575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RA13_RS13595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RA13_RS13595	COG1372	Participates in initiation and elongation during chromosome replication
RA13_RS13600	COG1780	Probably involved in ribonucleotide reductase function
RA13_RS13700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RA13_RS13710	COG3584	3D domain protein
RA13_RS13715	COG0587	DNA-directed DNA polymerase activity
RA13_RS13720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RA13_RS13725	COG0358	DNA primase activity
RA13_RS13730	COG0305	Participates in initiation and elongation during chromosome replication
RA13_RS13740	COG2887	Belongs to the helicase family. UvrD subfamily
RA13_RS13770	COG3420	alginic acid biosynthetic process
RA13_RS13770	COG5434	Belongs to the glycosyl hydrolase 28 family
RA13_RS13775	COG4195	phage-related replication protein
RA13_RS13810	COG1793	dna ligase
RA13_RS13855	COG1388	LysM domain
RA13_RS13920	COG3655	Transcriptional regulator
RA13_RS14015	COG3655	Transcriptional regulator
RA13_RS14100	COG0776	regulation of translation
RA13_RS14250	COG1196	nuclear chromosome segregation
RA13_RS14250	COG0739	heme binding
RA13_RS14250	COG0741	lytic transglycosylase activity
RA13_RS14260	COG2433	Pfam Transposase IS66
RA13_RS14270	COG5434	Belongs to the glycosyl hydrolase 28 family
RA13_RS14300	COG0457	Tetratricopeptide repeat
RA13_RS14310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RA13_RS14360	COG5444	nuclease activity
RA13_RS14365	COG4282	regulation of fungal-type cell wall biogenesis
RA13_RS14370	COG1525	nuclease
RA13_RS14390	COG0464	growth
RA13_RS14395	COG0860	N-Acetylmuramoyl-L-alanine amidase
RA13_RS14400	COG4112	unkown
RA13_RS14405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RA13_RS14410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RA13_RS14435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RA13_RS14455	COG2076	Multidrug Resistance protein
RA13_RS14465	COG1764	response to oxidative stress
RA13_RS14470	COG4195	phage-related replication protein
RA13_RS14480	COG1404	Belongs to the peptidase S8 family
RA13_RS14490	COG2124	cytochrome p450
RA13_RS14500	COG3321	synthase
RA13_RS14500	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS14500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS14500	COG4221	oxidoreductase activity
RA13_RS14505	COG3321	synthase
RA13_RS14505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS14505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS14505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RA13_RS14505	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS14520	COG1024	Enoyl-CoA hydratase
RA13_RS14525	COG1024	Enoyl-CoA hydratase
RA13_RS14530	COG3425	synthase
RA13_RS14540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RA13_RS14550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RA13_RS14555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RA13_RS14560	COG3226	Transcriptional regulator
RA13_RS14575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RA13_RS14580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RA13_RS14590	COG4550	Control of competence regulator ComK, YlbF/YmcA
RA13_RS14605	COG0156	8-amino-7-oxononanoate synthase activity
RA13_RS14610	COG1063	alcohol dehydrogenase
RA13_RS14615	COG2359	stage V sporulation protein S
RA13_RS14620	COG1692	metallophosphoesterase
RA13_RS14630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RA13_RS14635	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RA13_RS14645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RA13_RS14650	COG1426	Protein conserved in bacteria
RA13_RS14670	COG0612	Peptidase, M16
RA13_RS14675	COG0612	Peptidase, M16
RA13_RS14685	COG2814	Major facilitator Superfamily
RA13_RS14690	COG2188	Transcriptional regulator
RA13_RS14695	COG4980	gas vesicle protein
RA13_RS14695	COG1674	ftsk spoiiie
RA13_RS14705	COG0740	serine-type endopeptidase activity
RA13_RS14710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RA13_RS14720	COG0527	aspartate kinase activity
RA13_RS14725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RA13_RS14730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RA13_RS14735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RA13_RS14740	COG1873	PFAM PRC-barrel domain
RA13_RS14745	COG0612	Peptidase, M16
RA13_RS14750	COG0726	polysaccharide deacetylase
RA13_RS14755	COG1185	polyribonucleotide nucleotidyltransferase activity
RA13_RS14765	COG0196	riboflavin kinase activity
RA13_RS14770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RA13_RS14775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RA13_RS14780	COG1550	Protein conserved in bacteria
RA13_RS14785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RA13_RS14790	COG1358	cellular component organization or biogenesis
RA13_RS14795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
RA13_RS14800	COG0195	Participates in both transcription termination and antitermination
RA13_RS14805	COG0779	Required for maturation of 30S ribosomal subunits
RA13_RS14840	COG4589	Belongs to the CDS family
RA13_RS14845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RA13_RS14850	COG0233	cytoplasmic translational termination
RA13_RS14855	COG0528	UMP kinase activity
RA13_RS14860	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RA13_RS14875	COG1191	sigma factor activity
RA13_RS14880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RA13_RS14885	COG1776	CheC inhibitor of MCP methylation
RA13_RS14890	COG0835	chemotaxis
RA13_RS14895	COG2198	Histidine kinase
RA13_RS14895	COG0643	Histidine kinase
RA13_RS14900	COG2201	protein-glutamate methylesterase activity
RA13_RS14905	COG0455	bacterial-type flagellum organization
RA13_RS14910	COG1419	protein localization to endoplasmic reticulum
RA13_RS14915	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RA13_RS14920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RA13_RS14925	COG1684	flagellar biosynthetic protein fliR
RA13_RS14930	COG1987	bacterial-type flagellum assembly
RA13_RS14935	COG1338	Plays a role in the flagellum-specific transport system
RA13_RS14940	COG3190	flagellar
RA13_RS14945	COG2201	protein-glutamate methylesterase activity
RA13_RS14950	COG1776	CheC inhibitor of MCP methylation
RA13_RS14950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RA13_RS14955	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RA13_RS14960	COG1580	Controls the rotational direction of flagella during chemotaxis
RA13_RS14965	COG1582	Flagellar protein (FlbD)
RA13_RS14970	COG4786	Flagellar basal body rod
RA13_RS14975	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
RA13_RS14980	COG3144	bacterial-type flagellum assembly
RA13_RS14985	COG3334	PFAM MgtE intracellular
RA13_RS14990	COG2882	bacterial-type flagellum organization
RA13_RS14995	COG1157	protein secretion by the type III secretion system
RA13_RS15000	COG1317	bacterial-type flagellum organization
RA13_RS15005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RA13_RS15010	COG1766	The M ring may be actively involved in energy transduction
RA13_RS15015	COG1677	Flagellar hook-basal body complex protein FliE
RA13_RS15020	COG1558	bacterial-type flagellum-dependent cell motility
RA13_RS15025	COG1815	bacterial-type flagellum-dependent cell motility
RA13_RS15035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RA13_RS15040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RA13_RS15045	COG4974	Belongs to the 'phage' integrase family
RA13_RS15050	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
RA13_RS15055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RA13_RS15060	COG0758	DNA mediated transformation
RA13_RS15065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RA13_RS15075	COG2257	FlhB HrpN YscU SpaS Family
RA13_RS15085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RA13_RS15090	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RA13_RS15105	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RA13_RS15115	COG1837	Belongs to the UPF0109 family
RA13_RS15120	COG0228	four-way junction DNA binding
RA13_RS15130	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
RA13_RS15135	COG0552	protein localization to endoplasmic reticulum
RA13_RS15140	COG1196	nuclear chromosome segregation
RA13_RS15145	COG0571	ribonuclease III activity
RA13_RS15155	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS15160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RA13_RS15170	COG1349	DNA-binding transcription factor activity
RA13_RS15170	COG2050	protein possibly involved in aromatic compounds catabolism
RA13_RS15175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RA13_RS15180	COG1760	l-serine dehydratase
RA13_RS15185	COG1760	l-serine dehydratase
RA13_RS15190	COG1461	Dihydroxyacetone kinase
RA13_RS15195	COG1302	Protein conserved in bacteria
RA13_RS15200	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RA13_RS15210	COG1564	THIamine pyrophosphokinase
RA13_RS15215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RA13_RS15220	COG1162	GTPase activity
RA13_RS15225	COG0515	serine threonine protein kinase
RA13_RS15225	COG2815	serine threonine protein kinase
RA13_RS15230	COG0631	protein serine/threonine phosphatase activity
RA13_RS15240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RA13_RS15240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RA13_RS15245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RA13_RS15250	COG0242	peptide deformylase activity
RA13_RS15255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RA13_RS15260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RA13_RS15265	COG1758	RNA polymerase activity
RA13_RS15270	COG0194	GDP metabolic process
RA13_RS15280	COG1561	YicC-like family, N-terminal region
RA13_RS15285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RA13_RS15290	COG1293	RNA-binding protein homologous to eukaryotic snRNP
RA13_RS15305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RA13_RS15310	COG0529	Catalyzes the synthesis of activated sulfate
RA13_RS15315	COG2046	Belongs to the sulfate adenylyltransferase family
RA13_RS15320	COG0306	phosphate transporter
RA13_RS15325	COG0175	sulfate reduction
RA13_RS15330	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RA13_RS15335	COG0284	orotidine-5'-phosphate decarboxylase activity
RA13_RS15340	COG0167	dihydroorotate dehydrogenase activity
RA13_RS15345	COG0543	2 iron, 2 sulfur cluster binding
RA13_RS15350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RA13_RS15355	COG0505	Belongs to the CarA family
RA13_RS15360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RA13_RS15365	COG0540	Belongs to the ATCase OTCase family
RA13_RS15370	COG2233	PERMEase
RA13_RS15385	COG0564	pseudouridine synthase activity
RA13_RS15395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RA13_RS15400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RA13_RS15410	COG3599	regulation of cell shape
RA13_RS15415	COG2302	S4 RNA-binding domain
RA13_RS15420	COG0762	integral membrane protein
RA13_RS15425	COG1799	cell septum assembly
RA13_RS15430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RA13_RS15435	COG1496	oxidoreductase activity
RA13_RS15440	COG1873	PFAM PRC-barrel domain
RA13_RS15445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RA13_RS15450	COG1119	ATPase activity
RA13_RS15455	COG1191	sigma factor activity
RA13_RS15460	COG1191	sigma factor activity
RA13_RS15470	COG4412	M6 family metalloprotease domain protein
RA13_RS15470	COG1404	Belongs to the peptidase S8 family
RA13_RS15475	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RA13_RS15485	COG3856	small basic protein
RA13_RS15495	COG3879	Bacterial protein of unknown function (DUF881)
RA13_RS15500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RA13_RS15505	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RA13_RS15510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RA13_RS15515	COG0772	Belongs to the SEDS family
RA13_RS15520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RA13_RS15525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RA13_RS15530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RA13_RS15535	COG0768	penicillin binding
RA13_RS15540	COG0768	penicillin binding
RA13_RS15545	COG4839	cell division protein FtsL
RA13_RS15550	COG0275	rRNA processing
RA13_RS15555	COG2001	Belongs to the MraZ family
RA13_RS15560	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
RA13_RS15585	COG1399	metal-binding, possibly nucleic acid-binding protein
RA13_RS15590	COG1323	Belongs to the UPF0348 family
RA13_RS15595	COG3480	Lon protease (S16) C-terminal proteolytic domain
RA13_RS15600	COG1752	Esterase of the alpha-beta hydrolase superfamily
RA13_RS15605	COG3314	Sporulation integral membrane protein YlbJ
RA13_RS15610	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RA13_RS15615	COG0742	ribosomal rna small subunit methyltransferase
RA13_RS15620	COG4471	UPF0298 protein
RA13_RS15625	COG3679	Belongs to the UPF0342 family
RA13_RS15645	COG2340	Cysteine-rich secretory protein family
RA13_RS15650	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
RA13_RS15660	COG3336	cytochrome c oxidase
RA13_RS15665	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RA13_RS15670	COG1845	cytochrome c oxidase, subunit III
RA13_RS15675	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RA13_RS15680	COG2010	Cytochrome c
RA13_RS15680	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RA13_RS15690	COG1612	heme a metabolic process
RA13_RS15695	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
RA13_RS15700	COG0772	Belongs to the SEDS family
RA13_RS15705	COG4838	Belongs to the UPF0358 family
RA13_RS15715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RA13_RS15720	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RA13_RS15730	COG4896	Protein conserved in bacteria
RA13_RS15740	COG1217	gtp-binding protein TYPA
RA13_RS15765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RA13_RS15775	COG0483	inositol monophosphate 1-phosphatase activity
RA13_RS15785	COG4493	Belongs to the UPF0637 family
RA13_RS15790	COG4476	Belongs to the UPF0223 family
RA13_RS15795	COG1982	Orn Lys Arg decarboxylase major
RA13_RS15810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS15815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RA13_RS15820	COG0508	dehydrogenase complex catalyzes the overall conversion of
RA13_RS15825	COG0022	dehydrogenase e1 component
RA13_RS15830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RA13_RS15835	COG0497	DNA recombination
RA13_RS15845	COG0242	peptide deformylase activity
RA13_RS15850	COG0561	phosphatase activity
RA13_RS15860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RA13_RS15865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RA13_RS15870	COG0569	domain protein
RA13_RS15875	COG2105	PFAM AIG2 family protein
RA13_RS15875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
RA13_RS15880	COG3852	Histidine kinase
RA13_RS15885	COG2002	toxin-antitoxin pair type II binding
RA13_RS15890	COG1077	Cell shape determining protein MreB Mrl
RA13_RS15900	COG2309	aminopeptidase activity
RA13_RS15905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RA13_RS15910	COG0488	(ABC) transporter
RA13_RS15920	COG0681	Belongs to the peptidase S26 family
RA13_RS15925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS15925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RA13_RS15925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RA13_RS15930	COG1105	Belongs to the carbohydrate kinase PfkB family
RA13_RS15935	COG1349	DNA-binding transcription factor activity
RA13_RS15940	COG0577	efflux transmembrane transporter activity
RA13_RS15950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RA13_RS15960	COG1132	(ABC) transporter
RA13_RS15965	COG1132	(ABC) transporter
RA13_RS15970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RA13_RS15975	COG0314	molybdopterin synthase activity
RA13_RS15980	COG1763	Mo-molybdopterin cofactor biosynthetic process
RA13_RS15985	COG0303	'Molybdopterin
RA13_RS15990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RA13_RS15995	COG0746	molybdenum cofactor guanylyltransferase activity
RA13_RS16010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS16015	COG0450	alkyl hydroperoxide reductase
RA13_RS16020	COG0668	transmembrane transport
RA13_RS16030	COG1473	amidohydrolase
RA13_RS16035	COG2171	N-acyltransferase activity
RA13_RS16040	COG0716	FMN binding
RA13_RS16050	COG0716	FMN binding
RA13_RS16055	COG0583	DNA-binding transcription factor activity
RA13_RS16060	COG0517	IMP dehydrogenase activity
RA13_RS16070	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
RA13_RS16075	COG4703	Protein of unknown function (DUF1797)
RA13_RS16080	COG3546	catalase activity
RA13_RS16085	COG2200	EAL domain
RA13_RS16090	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS16095	COG1408	metallophosphoesterase
RA13_RS16100	COG1376	ErfK ybiS ycfS ynhG family protein
RA13_RS16105	COG2814	Major facilitator Superfamily
RA13_RS16115	COG0835	chemotaxis
RA13_RS16115	COG0784	Response regulator, receiver
RA13_RS16120	COG0436	Aminotransferase
RA13_RS16125	COG4191	Histidine kinase
RA13_RS16130	COG0768	penicillin binding
RA13_RS16135	COG2340	Cysteine-rich secretory protein family
RA13_RS16140	COG2084	Dehydrogenase
RA13_RS16145	COG0840	transmembrane signaling receptor activity
RA13_RS16150	COG0456	acetyltransferase
RA13_RS16155	COG1533	DNA photolyase activity
RA13_RS16165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RA13_RS16170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS16175	COG2190	(PTS) system
RA13_RS16175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS16175	COG1263	PTS System
RA13_RS16180	COG3711	transcriptional antiterminator
RA13_RS16185	COG1609	Transcriptional regulator
RA13_RS16190	COG0006	proline dipeptidase activity
RA13_RS16200	COG2217	Heavy metal translocating P-type atpase
RA13_RS16205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS16210	COG2244	polysaccharide biosynthetic process
RA13_RS16215	COG3773	Cell wall hydrolase
RA13_RS16225	COG4873	Protein conserved in bacteria
RA13_RS16240	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS16245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RA13_RS16250	COG0602	queuosine metabolic process
RA13_RS16255	COG0720	synthase
RA13_RS16270	COG3949	Membrane
RA13_RS16275	COG0542	response to heat
RA13_RS16280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RA13_RS16285	COG1360	Flagellar Motor Protein
RA13_RS16290	COG1846	Transcriptional regulator
RA13_RS16295	COG3852	Histidine kinase
RA13_RS16315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
RA13_RS16320	COG0235	Class ii aldolase
RA13_RS16330	COG1850	ribulose-bisphosphate carboxylase activity
RA13_RS16335	COG0436	Aminotransferase
RA13_RS16340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RA13_RS16345	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
RA13_RS16355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RA13_RS16360	COG5002	protein histidine kinase activity
RA13_RS16365	COG3594	Acyltransferase
RA13_RS16375	COG2323	membrane
RA13_RS16380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RA13_RS16385	COG0501	Belongs to the peptidase M48B family
RA13_RS16405	COG1191	sigma factor activity
RA13_RS16410	COG0861	Integral membrane protein TerC family
RA13_RS16420	COG0586	Pfam SNARE associated Golgi protein
RA13_RS16440	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RA13_RS16445	COG1793	dna ligase
RA13_RS16445	COG3285	dna ligase
RA13_RS16465	COG1408	metallophosphoesterase
RA13_RS16470	COG0726	polysaccharide deacetylase
RA13_RS16475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RA13_RS16480	COG1846	Transcriptional regulator
RA13_RS16495	COG0789	Transcriptional regulator
RA13_RS16500	COG2239	Acts as a magnesium transporter
RA13_RS16510	COG3212	peptidase
RA13_RS16550	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RA13_RS16555	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS16565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RA13_RS16575	COG0590	tRNA wobble adenosine to inosine editing
RA13_RS16585	COG0463	Glycosyl transferase, family 2
RA13_RS16585	COG0457	Tetratricopeptide repeat
RA13_RS16600	COG1764	response to oxidative stress
RA13_RS16605	COG1846	Transcriptional regulator
RA13_RS16610	COG1764	response to oxidative stress
RA13_RS16615	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RA13_RS16620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
RA13_RS16625	COG0788	formyltetrahydrofolate deformylase activity
RA13_RS16630	COG2076	Multidrug Resistance protein
RA13_RS16635	COG2076	Multidrug Resistance protein
RA13_RS16640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RA13_RS16645	COG2318	DinB family
RA13_RS16660	COG1695	Transcriptional regulator
RA13_RS16665	COG2323	membrane
RA13_RS16670	COG1607	acyl-coa hydrolase
RA13_RS16675	COG1834	amidinotransferase
RA13_RS16680	COG2706	6-phosphogluconolactonase activity
RA13_RS16685	COG4608	Belongs to the ABC transporter superfamily
RA13_RS16690	COG0791	NLP P60 protein
RA13_RS16695	COG4948	Mandelate Racemase Muconate Lactonizing
RA13_RS16700	COG1619	proteins homologs of microcin C7 resistance protein MccF
RA13_RS16705	COG4166	transmembrane transport
RA13_RS16720	COG0601	transmembrane transport
RA13_RS16725	COG2362	D-Aminopeptidase
RA13_RS16730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RA13_RS16735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RA13_RS16745	COG0463	Glycosyl transferase, family 2
RA13_RS16750	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RA13_RS16755	COG0346	lactoylglutathione lyase activity
RA13_RS16760	COG0531	amino acid
RA13_RS16765	COG1392	Phosphate transport regulator
RA13_RS16770	COG0306	phosphate transporter
RA13_RS16790	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS16790	COG5632	N-Acetylmuramoyl-L-alanine amidase
RA13_RS16830	COG3778	Protein conserved in bacteria
RA13_RS16835	COG3299	homolog of phage Mu protein gp47
RA13_RS16840	COG3628	GPW Gp25 family protein
RA13_RS16855	COG4193	domain, Protein
RA13_RS16860	COG1652	LysM domain
RA13_RS16865	COG3953	SLT domain
RA13_RS16865	COG5412	phage tail tape measure protein
RA13_RS16915	COG4653	Phage capsid family
RA13_RS16925	COG5518	Phage portal protein
RA13_RS16930	COG1783	phage Terminase large subunit
RA13_RS16935	COG5484	DNA packaging
RA13_RS16935	COG3728	DNA packaging
RA13_RS16940	COG1595	DNA-templated transcription, initiation
RA13_RS16955	COG1484	DNA-dependent DNA replication
RA13_RS16960	COG1522	sequence-specific DNA binding
RA13_RS16970	COG1396	sequence-specific DNA binding
RA13_RS16975	COG2856	Zn peptidase
RA13_RS16980	COG4195	phage-related replication protein
RA13_RS16990	COG1388	LysM domain
RA13_RS16990	COG3409	Peptidoglycan-binding domain 1 protein
RA13_RS16990	COG5632	N-Acetylmuramoyl-L-alanine amidase
RA13_RS17005	COG0457	Tetratricopeptide repeat
RA13_RS17010	COG2318	DinB family
RA13_RS17015	COG0730	response to heat
RA13_RS17020	COG2721	sulfolactate sulfo-lyase activity
RA13_RS17025	COG0246	Mannitol dehydrogenase
RA13_RS17035	COG2211	Major facilitator Superfamily
RA13_RS17040	COG1904	glucuronate isomerase
RA13_RS17050	COG2318	DinB family
RA13_RS17055	COG1252	NADH dehydrogenase
RA13_RS17065	COG4297	protein containing double-stranded beta helix domain
RA13_RS17070	COG0697	spore germination
RA13_RS17075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RA13_RS17080	COG0390	transport system, permease component
RA13_RS17085	COG1587	Uroporphyrinogen-III synthase
RA13_RS17110	COG2124	cytochrome p450
RA13_RS17120	COG1051	belongs to the nudix hydrolase family
RA13_RS17130	COG2427	Protein of unknown function (DUF1641)
RA13_RS17135	COG3383	formate dehydrogenase (NAD+) activity
RA13_RS17145	COG2205	protein histidine kinase activity
RA13_RS17155	COG0726	polysaccharide deacetylase
RA13_RS17175	COG1285	pathogenesis
RA13_RS17180	COG3209	COG3209 Rhs family protein
RA13_RS17235	COG5444	nuclease activity
RA13_RS17250	COG5505	Protein of unknown function (DUF819)
RA13_RS17260	COG0626	cystathionine gamma-synthase activity
RA13_RS17265	COG0626	cystathionine gamma-synthase activity
RA13_RS17270	COG2382	esterase
RA13_RS17280	COG2153	protein acetylation
RA13_RS17305	COG0210	DNA helicase
RA13_RS17360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RA13_RS17365	COG0351	phosphomethylpyrimidine kinase
RA13_RS17370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RA13_RS17375	COG2022	thiamine diphosphate biosynthetic process
RA13_RS17380	COG2104	thiamine diphosphate biosynthetic process
RA13_RS17385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RA13_RS17390	COG0352	thiamine-phosphate diphosphorylase activity
RA13_RS17395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
RA13_RS17400	COG0569	domain protein
RA13_RS17400	COG0475	glutathione-regulated potassium exporter activity
RA13_RS17415	COG0564	pseudouridine synthase activity
RA13_RS17420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RA13_RS17425	COG2357	RelA SpoT domain protein
RA13_RS17435	COG4116	CYTH
RA13_RS17440	COG0741	lytic transglycosylase activity
RA13_RS17445	COG2346	COG2346, Truncated hemoglobins
RA13_RS17450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RA13_RS17460	COG1164	Oligoendopeptidase f
RA13_RS17465	COG4469	Competence protein
RA13_RS17470	COG4862	establishment of competence for transformation
RA13_RS17475	COG0861	Integral membrane protein TerC family
RA13_RS17480	COG1393	Belongs to the ArsC family
RA13_RS17485	COG0456	acetyltransferase
RA13_RS17500	COG4608	Belongs to the ABC transporter superfamily
RA13_RS17505	COG0444	Belongs to the ABC transporter superfamily
RA13_RS17510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RA13_RS17515	COG0601	transmembrane transport
RA13_RS17520	COG4166	transmembrane transport
RA13_RS17530	COG0180	Tryptophanyl-tRNA synthetase
RA13_RS17540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RA13_RS17545	COG0601	transmembrane transport
RA13_RS17555	COG4608	Belongs to the ABC transporter superfamily
RA13_RS17560	COG0444	Belongs to the ABC transporter superfamily
RA13_RS17565	COG5504	Zn-dependent protease
RA13_RS17570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RA13_RS17575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RA13_RS17590	COG1744	ABC transporter substrate-binding protein PnrA-like
RA13_RS17600	COG2267	carboxylic ester hydrolase activity
RA13_RS17615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RA13_RS17620	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RA13_RS17625	COG0505	Belongs to the CarA family
RA13_RS17630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RA13_RS17645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RA13_RS17650	COG2271	Major facilitator Superfamily
RA13_RS17655	COG0277	FAD linked oxidase domain protein
RA13_RS17665	COG2151	metal-sulfur cluster biosynthetic enzyme
RA13_RS17675	COG0561	phosphatase activity
RA13_RS17690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS17695	COG1307	EDD domain protein, DegV family
RA13_RS17710	COG2996	Protein conserved in bacteria
RA13_RS17720	COG0646	methionine synthase
RA13_RS17720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
RA13_RS17725	COG2153	protein acetylation
RA13_RS17730	COG0454	-acetyltransferase
RA13_RS17735	COG2814	Major facilitator Superfamily
RA13_RS17740	COG4948	Mandelate Racemase Muconate Lactonizing
RA13_RS17745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS17750	COG1809	phosphosulfolactate synthase activity
RA13_RS17760	COG0175	sulfate reduction
RA13_RS17765	COG2046	Belongs to the sulfate adenylyltransferase family
RA13_RS17770	COG0529	Catalyzes the synthesis of activated sulfate
RA13_RS17785	COG1357	PFAM Pentapeptide repeats (8 copies)
RA13_RS17800	COG2318	DinB family
RA13_RS17805	COG0673	inositol 2-dehydrogenase activity
RA13_RS17810	COG1609	Transcriptional regulator
RA13_RS17815	COG0109	protoheme IX farnesyltransferase activity
RA13_RS17820	COG2207	Transcriptional regulator
RA13_RS17820	COG1917	Cupin 2, conserved barrel domain protein
RA13_RS17825	COG0534	Mate efflux family protein
RA13_RS17830	COG1562	ergosterol biosynthetic process
RA13_RS17835	COG0367	asparagine synthase
RA13_RS17855	COG0179	Fumarylacetoacetate (FAA) hydrolase
RA13_RS17860	COG5337	Spore coat protein CotH
RA13_RS17870	COG2311	Membrane
RA13_RS17905	COG1403	HNH endonuclease
RA13_RS17910	COG0419	ATPase involved in DNA repair
RA13_RS17915	COG0420	3'-5' exonuclease activity
RA13_RS17920	COG1074	ATP-dependent DNA helicase activity
RA13_RS17925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
RA13_RS17930	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RA13_RS17940	COG4533	DNA binding
RA13_RS17945	COG2814	Major facilitator Superfamily
RA13_RS17945	COG0477	Major facilitator Superfamily
RA13_RS17950	COG3180	Ammonia monooxygenase
RA13_RS17955	COG1846	Transcriptional regulator
RA13_RS17960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RA13_RS17965	COG0681	Belongs to the peptidase S26 family
RA13_RS17970	COG0398	Pfam SNARE associated Golgi protein
RA13_RS17985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS17995	COG4903	ComK protein
RA13_RS18005	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS18010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RA13_RS18010	COG0723	plastoquinol--plastocyanin reductase activity
RA13_RS18015	COG0840	transmembrane signaling receptor activity
RA13_RS18025	COG1024	Enoyl-CoA hydratase
RA13_RS18030	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS18035	COG2084	Dehydrogenase
RA13_RS18040	COG1960	acyl-CoA dehydrogenase activity
RA13_RS18045	COG0183	Belongs to the thiolase family
RA13_RS18050	COG0406	alpha-ribazole phosphatase activity
RA13_RS18055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS18060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS18065	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RA13_RS18070	COG0604	alcohol dehydrogenase
RA13_RS18075	COG0456	acetyltransferase
RA13_RS18080	COG1404	Belongs to the peptidase S8 family
RA13_RS18085	COG0501	Belongs to the peptidase M48B family
RA13_RS18100	COG0702	epimerase
RA13_RS18105	COG0095	Lipoate-protein ligase
RA13_RS18110	COG1234	tRNA 3'-trailer cleavage
RA13_RS18120	COG1301	dicarboxylic acid transport
RA13_RS18125	COG1363	Peptidase, m42
RA13_RS18135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RA13_RS18140	COG1511	domain protein
RA13_RS18145	COG1309	transcriptional regulator
RA13_RS18150	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
RA13_RS18160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RA13_RS18165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RA13_RS18170	COG2329	Antibiotic biosynthesis monooxygenase
RA13_RS18175	COG3069	C4-dicarboxylate transmembrane transporter activity
RA13_RS18180	COG1473	amidohydrolase
RA13_RS18190	COG4473	ABC transporter
RA13_RS18195	COG1131	(ABC) transporter
RA13_RS18200	COG0537	adenosine 5'-monophosphoramidase activity
RA13_RS18205	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RA13_RS18220	COG4980	gas vesicle protein
RA13_RS18260	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RA13_RS18270	COG3481	metal-dependent phosphohydrolase, HD sub domain
RA13_RS18275	COG4717	serine-type aminopeptidase activity
RA13_RS18280	COG0420	3'-5' exonuclease activity
RA13_RS18285	COG1668	transmembrane transport
RA13_RS18290	COG4152	abc transporter atp-binding protein
RA13_RS18300	COG1024	Enoyl-CoA hydratase
RA13_RS18310	COG0490	domain, Protein
RA13_RS18315	COG0475	glutathione-regulated potassium exporter activity
RA13_RS18325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RA13_RS18330	COG0561	phosphatase activity
RA13_RS18345	COG4399	Belongs to the UPF0754 family
RA13_RS18355	COG0189	ligase activity
RA13_RS18360	COG0189	ligase activity
RA13_RS18380	COG0702	epimerase
RA13_RS18385	COG1132	(ABC) transporter
RA13_RS18390	COG1132	(ABC) transporter
RA13_RS18395	COG0589	response to stress
RA13_RS18400	COG1757	Na H antiporter
RA13_RS18405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RA13_RS18410	COG0726	polysaccharide deacetylase
RA13_RS18415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RA13_RS18420	COG0668	transmembrane transport
RA13_RS18430	COG0584	glycerophosphoryl diester phosphodiesterase
RA13_RS18435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RA13_RS18440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RA13_RS18445	COG1253	flavin adenine dinucleotide binding
RA13_RS18455	COG0789	Transcriptional regulator
RA13_RS18460	COG1253	flavin adenine dinucleotide binding
RA13_RS18465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS18470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RA13_RS18475	COG0204	Acyl-transferase
RA13_RS18480	COG0667	Aldo Keto reductase
RA13_RS18485	COG1595	DNA-templated transcription, initiation
RA13_RS18500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RA13_RS18505	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS18510	COG4187	Peptidase family M20/M25/M40
RA13_RS18515	COG0833	amino acid
RA13_RS18520	COG0456	acetyltransferase
RA13_RS18540	COG0531	amino acid
RA13_RS18545	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS18550	COG0372	Belongs to the citrate synthase family
RA13_RS18555	COG0583	DNA-binding transcription factor activity
RA13_RS18560	COG0791	NLP P60 protein
RA13_RS18560	COG1388	LysM domain
RA13_RS18565	COG1785	Belongs to the alkaline phosphatase family
RA13_RS18570	COG2719	SpoVR family
RA13_RS18575	COG0668	transmembrane transport
RA13_RS18580	COG1959	2 iron, 2 sulfur cluster binding
RA13_RS18585	COG0791	NLP P60 protein
RA13_RS18585	COG1388	LysM domain
RA13_RS18600	COG0431	NADPH-dependent FMN reductase
RA13_RS18605	COG2197	response regulator
RA13_RS18610	COG2203	Gaf domain
RA13_RS18610	COG4585	Histidine kinase
RA13_RS18615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RA13_RS18620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RA13_RS18625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RA13_RS18630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RA13_RS18635	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
RA13_RS18640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RA13_RS18650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RA13_RS18650	COG3153	acetyltransferase
RA13_RS18655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RA13_RS18660	COG0517	IMP dehydrogenase activity
RA13_RS18670	COG0564	pseudouridine synthase activity
RA13_RS18675	COG3764	Sortase (surface protein transpeptidase)
RA13_RS18690	COG5577	PFAM Coat F domain
RA13_RS18710	COG1823	symporter activity
RA13_RS18715	COG3706	GGDEF domain
RA13_RS18720	COG1464	Belongs to the NlpA lipoprotein family
RA13_RS18730	COG1278	Cold shock
RA13_RS18735	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RA13_RS18740	COG1131	(ABC) transporter
RA13_RS18745	COG1131	(ABC) transporter
RA13_RS18750	COG1725	Transcriptional regulator
RA13_RS18765	COG0655	NAD(P)H dehydrogenase (quinone) activity
RA13_RS18770	COG2814	Major facilitator Superfamily
RA13_RS18775	COG1566	PFAM secretion protein HlyD family protein
RA13_RS18780	COG1846	Transcriptional regulator
RA13_RS18785	COG2718	Belongs to the UPF0229 family
RA13_RS18790	COG2766	serine protein kinase
RA13_RS18795	COG1664	Polymer-forming cytoskeletal
RA13_RS18800	COG1664	Polymer-forming cytoskeletal
RA13_RS18805	COG0789	Transcriptional regulator
RA13_RS18810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RA13_RS18820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RA13_RS18825	COG3382	B3 4 domain protein
RA13_RS18835	COG1476	TRANSCRIPTIONal
RA13_RS18845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RA13_RS18855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RA13_RS18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RA13_RS18870	COG0753	catalase activity
RA13_RS18880	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RA13_RS18890	COG4326	sporulation control protein
RA13_RS19015	COG0735	belongs to the Fur family
RA13_RS19020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RA13_RS19025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RA13_RS19030	COG4129	membrane
RA13_RS19035	COG1132	(ABC) transporter
RA13_RS19040	COG3557	Belongs to the UPF0374 family
RA13_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS19065	COG1194	a g-specific adenine glycosylase
RA13_RS19070	COG1988	membrane-bound metal-dependent
RA13_RS19075	COG4485	Bacterial membrane protein, YfhO
RA13_RS19080	COG0463	Glycosyl transferase, family 2
RA13_RS19085	COG0596	Alpha beta hydrolase
RA13_RS19090	COG5658	integral membrane protein
RA13_RS19095	COG3103	Sh3 type 3 domain protein
RA13_RS19110	COG2814	Major facilitator Superfamily
RA13_RS19120	COG2137	regulation of response to DNA damage stimulus
RA13_RS19125	COG1090	epimerase
RA13_RS19140	COG0778	Nitroreductase
RA13_RS19145	COG0384	phenazine biosynthesis protein PhzF
RA13_RS19150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS19155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS19165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RA13_RS19175	COG1846	Transcriptional regulator
RA13_RS19180	COG2814	Major facilitator Superfamily
RA13_RS19185	COG2318	DinB family
RA13_RS19190	COG0604	alcohol dehydrogenase
RA13_RS19195	COG2732	(Barnase) inhibitor
RA13_RS19200	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
RA13_RS19205	COG1695	Transcriptional regulator
RA13_RS19210	COG0842	Transport permease protein
RA13_RS19220	COG2514	catechol 2,3-dioxygenase activity
RA13_RS19225	COG2259	Doxx family
RA13_RS19230	COG1132	(ABC) transporter
RA13_RS19235	COG1132	(ABC) transporter
RA13_RS19240	COG5434	Belongs to the glycosyl hydrolase 28 family
RA13_RS19245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS19245	COG1263	PTS System
RA13_RS19250	COG1737	Transcriptional regulator
RA13_RS19255	COG1486	melibiose metabolic process
RA13_RS19260	COG4842	Belongs to the WXG100 family
RA13_RS19280	COG1742	UPF0060 membrane protein
RA13_RS19290	COG3284	Transcriptional regulator
RA13_RS19295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RA13_RS19300	COG0508	dehydrogenase complex catalyzes the overall conversion of
RA13_RS19310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RA13_RS19315	COG4637	Psort location Cytoplasmic, score
RA13_RS19320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RA13_RS19325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RA13_RS19335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
RA13_RS19340	COG0598	Magnesium transport protein CorA
RA13_RS19350	COG2084	Dehydrogenase
RA13_RS19355	COG0726	polysaccharide deacetylase
RA13_RS19365	COG0535	radical SAM domain protein
RA13_RS19370	COG0668	transmembrane transport
RA13_RS19380	COG0387	Pfam Sodium calcium exchanger
RA13_RS19385	COG0477	Major facilitator Superfamily
RA13_RS19390	COG1295	ribonuclease BN
RA13_RS19395	COG4980	gas vesicle protein
RA13_RS19400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RA13_RS19405	COG4840	Belongs to the UPF0435 family
RA13_RS19410	COG2814	Major facilitator Superfamily
RA13_RS19420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RA13_RS19425	COG2814	Major facilitator Superfamily
RA13_RS19430	COG1609	Transcriptional regulator
RA13_RS19435	COG0693	protein deglycase activity
RA13_RS19440	COG0737	Belongs to the 5'-nucleotidase family
RA13_RS19445	COG0778	Nitroreductase
RA13_RS19450	COG2188	Transcriptional regulator
RA13_RS19455	COG0366	Alpha amylase catalytic
RA13_RS19460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS19460	COG1263	PTS System
RA13_RS19475	COG1368	sulfuric ester hydrolase activity
RA13_RS19480	COG1263	PTS System
RA13_RS19480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RA13_RS19485	COG0024	Methionine aminopeptidase
RA13_RS19505	COG2258	MOSC domain
RA13_RS19510	COG1254	Belongs to the acylphosphatase family
RA13_RS19515	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RA13_RS19520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RA13_RS19525	COG2851	Citrate transporter
RA13_RS19530	COG3181	Tripartite tricarboxylate transporter family receptor
RA13_RS19535	COG4565	transcriptional regulatory protein
RA13_RS19545	COG0471	metal ion transport
RA13_RS19555	COG3866	Pectate lyase
RA13_RS19570	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
RA13_RS19575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS19580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS19585	COG1120	ATPase activity
RA13_RS19590	COG2130	NADP-dependent
RA13_RS19595	COG0513	Belongs to the DEAD box helicase family
RA13_RS19600	COG0488	(ABC) transporter
RA13_RS19605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RA13_RS19610	COG2814	Major facilitator Superfamily
RA13_RS19615	COG0789	Transcriptional regulator
RA13_RS19620	COG0488	(ABC) transporter
RA13_RS19625	COG0463	Glycosyl transferase, family 2
RA13_RS19630	COG0840	transmembrane signaling receptor activity
RA13_RS19635	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS19640	COG0531	amino acid
RA13_RS19645	COG2223	nitrite transmembrane transporter activity
RA13_RS19650	COG1442	glycosyl transferase family 8
RA13_RS19655	COG1216	Glycosyl transferase, family 2
RA13_RS19660	COG1442	glycosyl transferase family 8
RA13_RS19665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RA13_RS19670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RA13_RS19675	COG1368	sulfuric ester hydrolase activity
RA13_RS19685	COG1131	(ABC) transporter
RA13_RS19700	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RA13_RS19700	COG2124	cytochrome p450
RA13_RS19710	COG0670	Belongs to the BI1 family
RA13_RS19715	COG0196	riboflavin kinase activity
RA13_RS19720	COG5583	Uncharacterized small protein (DUF2292)
RA13_RS19725	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS19730	COG0346	lactoylglutathione lyase activity
RA13_RS19735	COG2329	Antibiotic biosynthesis monooxygenase
RA13_RS19740	COG2323	membrane
RA13_RS19745	COG1486	melibiose metabolic process
RA13_RS19750	COG0395	ABC-type sugar transport system, permease component
RA13_RS19755	COG4209	transmembrane transport
RA13_RS19760	COG1653	transport
RA13_RS19770	COG1874	Beta-galactosidase
RA13_RS19775	COG2755	lipolytic protein G-D-S-L family
RA13_RS19780	COG0667	Aldo Keto reductase
RA13_RS19785	COG3401	FG-GAP repeat protein
RA13_RS19790	COG3401	FG-GAP repeat protein
RA13_RS19795	COG5578	integral membrane protein
RA13_RS19805	COG2755	lipolytic protein G-D-S-L family
RA13_RS19810	COG2207	Transcriptional regulator
RA13_RS19815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RA13_RS19825	COG1175	transmembrane transport
RA13_RS19830	COG1653	transport
RA13_RS19835	COG4753	response regulator
RA13_RS19835	COG2207	Transcriptional regulator
RA13_RS19845	COG5578	integral membrane protein
RA13_RS19855	COG0454	-acetyltransferase
RA13_RS19860	COG3546	catalase activity
RA13_RS19885	COG0457	Tetratricopeptide repeat
RA13_RS19895	COG5444	nuclease activity
RA13_RS19910	COG0457	Tetratricopeptide repeat
RA13_RS19945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RA13_RS19950	COG1597	lipid kinase activity
RA13_RS19955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RA13_RS19960	COG1309	transcriptional regulator
RA13_RS19970	COG0154	amidase activity
RA13_RS19980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS19985	COG1285	pathogenesis
RA13_RS19990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RA13_RS20000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RA13_RS20005	COG0210	DNA helicase
RA13_RS20010	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
RA13_RS20015	COG0069	glutamate synthase activity
RA13_RS20020	COG4496	protein, YerC YecD
RA13_RS20025	COG1470	cell adhesion involved in biofilm formation
RA13_RS20030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RA13_RS20040	COG0531	amino acid
RA13_RS20045	COG1522	sequence-specific DNA binding
RA13_RS20050	COG0151	Belongs to the GarS family
RA13_RS20055	COG0138	bifunctional purine biosynthesis protein purh
RA13_RS20060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RA13_RS20070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RA13_RS20075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RA13_RS20080	COG0047	phosphoribosylformylglycinamidine synthase activity
RA13_RS20085	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RA13_RS20090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RA13_RS20095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RA13_RS20100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RA13_RS20105	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RA13_RS20115	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
RA13_RS20125	COG3064	Membrane
RA13_RS20130	COG2252	PERMEase
RA13_RS20150	COG1305	Transglutaminase-like
RA13_RS20155	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
RA13_RS20160	COG0714	Associated with various cellular activities
RA13_RS20165	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RA13_RS20175	COG1113	amino acid transport
RA13_RS20180	COG2132	Multicopper oxidase
RA13_RS20190	COG2267	carboxylic ester hydrolase activity
RA13_RS20205	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RA13_RS20210	COG1063	alcohol dehydrogenase
RA13_RS20215	COG2814	Major facilitator Superfamily
RA13_RS20220	COG1846	Transcriptional regulator
RA13_RS20225	COG0778	Nitroreductase
RA13_RS20235	COG1595	DNA-templated transcription, initiation
RA13_RS20245	COG4260	virion core protein, lumpy skin disease virus
RA13_RS20250	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RA13_RS20255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RA13_RS20260	COG1842	Phage shock protein A
RA13_RS20265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RA13_RS20275	COG1063	alcohol dehydrogenase
RA13_RS20280	COG0457	Tetratricopeptide repeat
RA13_RS20320	COG1266	CAAX protease self-immunity
RA13_RS20330	COG0805	protein transport
RA13_RS20335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RA13_RS20345	COG0315	cyclic pyranopterin monophosphate synthase activity
RA13_RS20350	COG0488	(ABC) transporter
RA13_RS20355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RA13_RS20360	COG0456	acetyltransferase
RA13_RS20365	COG1214	PFAM Peptidase M22, glycoprotease
RA13_RS20370	COG0802	atpase or kinase
RA13_RS20375	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RA13_RS20415	COG1378	Sugar-specific transcriptional regulator TrmB
RA13_RS20430	COG2807	transmembrane transport
RA13_RS20435	COG2186	Transcriptional regulator
RA13_RS20440	COG2814	Major facilitator Superfamily
RA13_RS20455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RA13_RS20460	COG5434	Belongs to the glycosyl hydrolase 28 family
RA13_RS20465	COG1174	glycine betaine transport
RA13_RS20470	COG1125	glycine betaine transport
RA13_RS20470	COG0517	IMP dehydrogenase activity
RA13_RS20485	COG1785	Belongs to the alkaline phosphatase family
RA13_RS20500	COG1819	glycosyl
RA13_RS20505	COG1388	LysM domain
RA13_RS20505	COG3858	chitin binding
RA13_RS20515	COG2814	Major facilitator Superfamily
RA13_RS20525	COG2602	Beta-lactamase
RA13_RS20540	COG0596	Alpha beta hydrolase
RA13_RS20545	COG0488	(ABC) transporter
RA13_RS20555	COG1522	sequence-specific DNA binding
RA13_RS20560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RA13_RS20580	COG1482	cell wall glycoprotein biosynthetic process
RA13_RS20585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RA13_RS20585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RA13_RS20585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS20590	COG3711	transcriptional antiterminator
RA13_RS20590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS20595	COG2409	Drug exporters of the RND superfamily
RA13_RS20595	COG1033	growth of symbiont in host cell
RA13_RS20600	COG1846	Transcriptional regulator
RA13_RS20610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS20620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RA13_RS20625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RA13_RS20630	COG0640	Transcriptional regulator
RA13_RS20635	COG0640	Transcriptional regulator
RA13_RS20640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
RA13_RS20645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RA13_RS20650	COG0697	spore germination
RA13_RS20665	COG2814	Major facilitator Superfamily
RA13_RS20685	COG0697	spore germination
RA13_RS20690	COG0456	acetyltransferase
RA13_RS20695	COG1846	Transcriptional regulator
RA13_RS20700	COG2364	Membrane
RA13_RS20705	COG2315	Protein conserved in bacteria
RA13_RS20710	COG1329	Transcriptional regulator
RA13_RS20715	COG1278	Cold shock
RA13_RS20725	COG3239	Fatty acid desaturase
RA13_RS20730	COG2814	Major facilitator Superfamily
RA13_RS20735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RA13_RS20750	COG1522	sequence-specific DNA binding
RA13_RS20765	COG0745	RESPONSE REGULATOR receiver
RA13_RS20770	COG5002	protein histidine kinase activity
RA13_RS20825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RA13_RS20830	COG0251	oxidation-reduction process
RA13_RS20900	COG3091	SprT-like family
RA13_RS20910	COG2183	response to ionizing radiation
RA13_RS20915	COG2208	phosphoserine phosphatase activity
RA13_RS20920	COG1191	sigma factor activity
RA13_RS20925	COG2172	sigma factor antagonist activity
RA13_RS20930	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS20935	COG2208	phosphoserine phosphatase activity
RA13_RS20940	COG2172	sigma factor antagonist activity
RA13_RS20945	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS20950	COG1366	Belongs to the anti-sigma-factor antagonist family
RA13_RS20955	COG2337	Toxic component of a toxin-antitoxin (TA) module
RA13_RS20960	COG0864	Transcriptional regulator
RA13_RS20965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RA13_RS20970	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RA13_RS20975	COG0736	holo-[acyl-carrier-protein] synthase activity
RA13_RS20980	COG0705	Rhomboid family
RA13_RS20985	COG3428	Bacterial PH domain
RA13_RS20990	COG3402	PFAM membrane-flanked domain
RA13_RS20995	COG0513	Belongs to the DEAD box helicase family
RA13_RS21005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RA13_RS21010	COG1181	Belongs to the D-alanine--D-alanine ligase family
RA13_RS21015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RA13_RS21020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
RA13_RS21035	COG1960	acyl-CoA dehydrogenase activity
RA13_RS21045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
RA13_RS21050	COG1131	(ABC) transporter
RA13_RS21055	COG0628	permease
RA13_RS21060	COG1301	dicarboxylic acid transport
RA13_RS21065	COG4565	transcriptional regulatory protein
RA13_RS21070	COG3290	protein histidine kinase activity
RA13_RS21075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
RA13_RS21080	COG3546	catalase activity
RA13_RS21090	COG0662	Cupin 2, conserved barrel domain protein
RA13_RS21095	COG3729	General stress protein
RA13_RS21100	COG2217	Heavy metal translocating P-type atpase
RA13_RS21105	COG4876	unkown
RA13_RS21110	COG2261	transglycosylase associated protein
RA13_RS21115	COG1914	H( )-stimulated, divalent metal cation uptake system
RA13_RS21145	COG0028	Belongs to the TPP enzyme family
RA13_RS21155	COG0531	amino acid
RA13_RS21170	COG3706	GGDEF domain
RA13_RS21175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
RA13_RS21185	COG1522	sequence-specific DNA binding
RA13_RS21200	COG2814	Major facilitator Superfamily
RA13_RS21215	COG3871	stress protein (general stress protein 26)
RA13_RS21220	COG1917	Cupin 2, conserved barrel domain protein
RA13_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS21235	COG0318	PFAM AMP-dependent synthetase and ligase
RA13_RS21240	COG3711	transcriptional antiterminator
RA13_RS21245	COG4989	oxidoreductase activity
RA13_RS21250	COG0768	penicillin binding
RA13_RS21255	COG2329	Antibiotic biosynthesis monooxygenase
RA13_RS21270	COG1414	Transcriptional regulator
RA13_RS21275	COG1984	allophanate hydrolase subunit 2
RA13_RS21280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RA13_RS21285	COG4336	lyase activity
RA13_RS21290	COG1914	H( )-stimulated, divalent metal cation uptake system
RA13_RS21295	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RA13_RS21300	COG0561	phosphatase activity
RA13_RS21315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RA13_RS21320	COG0412	Dienelactone hydrolase
RA13_RS21325	COG0246	Mannitol dehydrogenase
RA13_RS21330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RA13_RS21335	COG2213	PTS system mannitol-specific
RA13_RS21345	COG1349	DNA-binding transcription factor activity
RA13_RS21350	COG2372	response to copper ion
RA13_RS21350	COG1276	copper resistance
RA13_RS21355	COG4549	nuclear export factor GLE1
RA13_RS21360	COG1028	Short-chain dehydrogenase reductase Sdr
RA13_RS21365	COG4975	Glucose uptake
RA13_RS21370	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS21375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RA13_RS21380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RA13_RS21385	COG0640	Transcriptional regulator
RA13_RS21390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
RA13_RS21395	COG0778	Nitroreductase
RA13_RS21400	COG0457	Tetratricopeptide repeat
RA13_RS21405	COG1309	transcriptional regulator
RA13_RS21410	COG2814	Major facilitator Superfamily
RA13_RS21415	COG4607	ABC-type enterochelin transport system periplasmic component
RA13_RS21420	COG4604	ABC transporter, ATP-binding protein
RA13_RS21425	COG4605	iron ion homeostasis
RA13_RS21430	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RA13_RS21435	COG0527	aspartate kinase activity
RA13_RS21455	COG0457	Tetratricopeptide repeat
RA13_RS21460	COG3850	Histidine kinase
RA13_RS21460	COG5002	protein histidine kinase activity
RA13_RS21470	COG0577	efflux transmembrane transporter activity
RA13_RS21475	COG1136	(ABC) transporter
RA13_RS21480	COG2079	MmgE PrpD family protein
RA13_RS21485	COG1473	amidohydrolase
RA13_RS21490	COG1126	abc transporter atp-binding protein
RA13_RS21495	COG0765	amino acid transport
RA13_RS21500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RA13_RS21505	COG0456	acetyltransferase
RA13_RS21510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RA13_RS21515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
RA13_RS21535	COG5434	Belongs to the glycosyl hydrolase 28 family
RA13_RS21540	COG3104	oligopeptide transport
RA13_RS21545	COG0596	Alpha beta hydrolase
RA13_RS21560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RA13_RS21565	COG0163	prenyltransferase activity
RA13_RS21570	COG0583	DNA-binding transcription factor activity
RA13_RS21575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RA13_RS21585	COG1126	abc transporter atp-binding protein
RA13_RS21590	COG2364	Membrane
RA13_RS21600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RA13_RS21605	COG0697	spore germination
RA13_RS21615	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
RA13_RS21620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS21625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS21630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RA13_RS21635	COG1733	regulation of RNA biosynthetic process
RA13_RS21640	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
RA13_RS21645	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RA13_RS21650	COG0840	transmembrane signaling receptor activity
RA13_RS21650	COG3290	protein histidine kinase activity
RA13_RS21655	COG3209	COG3209 Rhs family protein
RA13_RS21665	COG2723	6-phospho-beta-galactosidase activity
RA13_RS21680	COG1714	RDD family
RA13_RS21690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RA13_RS21695	COG0765	amino acid transport
RA13_RS21700	COG0523	cobalamin synthesis protein
RA13_RS21705	COG1376	ErfK ybiS ycfS ynhG family protein
RA13_RS21710	COG1469	GTP cyclohydrolase I activity
RA13_RS21715	COG2223	nitrite transmembrane transporter activity
RA13_RS21720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RA13_RS21725	COG0243	molybdopterin cofactor binding
RA13_RS21730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RA13_RS21735	COG2146	nitrite reductase [NAD(P)H] activity
RA13_RS21740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RA13_RS21740	COG1587	Uroporphyrinogen-III synthase
RA13_RS21755	COG0701	Predicted permease
RA13_RS21760	COG3689	TIGRFAM TIGR03943 family protein
RA13_RS21765	COG2508	Transcriptional regulator
RA13_RS21770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RA13_RS21775	COG1012	belongs to the aldehyde dehydrogenase family
RA13_RS21785	COG3541	Predicted nucleotidyltransferase
RA13_RS21790	COG3458	cephalosporin-C deacetylase activity
RA13_RS21800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RA13_RS21805	COG1082	Xylose isomerase domain protein TIM barrel
RA13_RS21810	COG1660	Displays ATPase and GTPase activities
RA13_RS21820	COG3665	Urea carboxylase-associated protein
RA13_RS21825	COG1113	amino acid transport
RA13_RS21830	COG3403	YqcI/YcgG family
RA13_RS21835	COG1280	lysine exporter protein (LysE YggA)
RA13_RS21840	COG1846	Transcriptional regulator
RA13_RS21845	COG2814	Major facilitator Superfamily
RA13_RS21850	COG1620	l-lactate permease
RA13_RS21855	COG0039	L-malate dehydrogenase activity