locus-tag	class	description
TD68_RS00015	COG1785	Belongs to the alkaline phosphatase family
TD68_RS00025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD68_RS00030	COG1125	glycine betaine transport
TD68_RS00030	COG0517	IMP dehydrogenase activity
TD68_RS00035	COG1174	glycine betaine transport
TD68_RS00040	COG5434	Belongs to the glycosyl hydrolase 28 family
TD68_RS00045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS00060	COG2814	Major facilitator Superfamily
TD68_RS00065	COG2186	Transcriptional regulator
TD68_RS00070	COG2807	transmembrane transport
TD68_RS00085	COG1378	Sugar-specific transcriptional regulator TrmB
TD68_RS00130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TD68_RS00135	COG0802	atpase or kinase
TD68_RS00140	COG1214	PFAM Peptidase M22, glycoprotease
TD68_RS00145	COG0456	acetyltransferase
TD68_RS00150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TD68_RS00155	COG0488	(ABC) transporter
TD68_RS00160	COG0315	cyclic pyranopterin monophosphate synthase activity
TD68_RS00170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TD68_RS00175	COG0805	protein transport
TD68_RS00185	COG1266	CAAX protease self-immunity
TD68_RS00215	COG2197	response regulator
TD68_RS00220	COG0457	Tetratricopeptide repeat
TD68_RS00225	COG1063	alcohol dehydrogenase
TD68_RS00230	COG2211	Major facilitator Superfamily
TD68_RS00235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_RS00240	COG1842	Phage shock protein A
TD68_RS00245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TD68_RS00250	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
TD68_RS00255	COG4260	virion core protein, lumpy skin disease virus
TD68_RS00265	COG1595	DNA-templated transcription, initiation
TD68_RS00275	COG0778	Nitroreductase
TD68_RS00280	COG1846	Transcriptional regulator
TD68_RS00285	COG2814	Major facilitator Superfamily
TD68_RS00290	COG1063	alcohol dehydrogenase
TD68_RS00295	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TD68_RS00300	COG0823	Involved in the tonB-independent uptake of proteins
TD68_RS00310	COG2267	carboxylic ester hydrolase activity
TD68_RS00320	COG2132	Multicopper oxidase
TD68_RS00325	COG1113	amino acid transport
TD68_RS00335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TD68_RS00340	COG0714	Associated with various cellular activities
TD68_RS00345	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
TD68_RS00350	COG1305	Transglutaminase-like
TD68_RS00355	COG0519	Catalyzes the synthesis of GMP from XMP
TD68_RS00355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TD68_RS00370	COG2252	PERMEase
TD68_RS00375	COG3064	Membrane
TD68_RS00380	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
TD68_RS00390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TD68_RS00395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TD68_RS00400	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TD68_RS00405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TD68_RS00410	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TD68_RS00415	COG0047	phosphoribosylformylglycinamidine synthase activity
TD68_RS00420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TD68_RS00425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TD68_RS00435	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TD68_RS00440	COG0138	bifunctional purine biosynthesis protein purh
TD68_RS00445	COG0151	Belongs to the GarS family
TD68_RS00450	COG1522	sequence-specific DNA binding
TD68_RS00455	COG0531	amino acid
TD68_RS00465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TD68_RS00470	COG1470	cell adhesion involved in biofilm formation
TD68_RS00475	COG4496	protein, YerC YecD
TD68_RS00480	COG0069	glutamate synthase activity
TD68_RS00485	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TD68_RS00490	COG0210	DNA helicase
TD68_RS00495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TD68_RS00500	COG4851	CamS sex pheromone cAM373 precursor
TD68_RS00505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_RS00510	COG1285	pathogenesis
TD68_RS00515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_RS00525	COG0154	amidase activity
TD68_RS00535	COG1309	transcriptional regulator
TD68_RS00540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TD68_RS00545	COG1597	lipid kinase activity
TD68_RS00550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TD68_RS00555	COG2197	response regulator
TD68_RS00565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_RS00575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD68_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS00590	COG1131	(ABC) transporter
TD68_RS00615	COG0457	Tetratricopeptide repeat
TD68_RS00630	COG3391	amine dehydrogenase activity
TD68_RS00635	COG3391	amine dehydrogenase activity
TD68_RS00645	COG0457	Tetratricopeptide repeat
TD68_RS00665	COG3546	catalase activity
TD68_RS00670	COG0454	-acetyltransferase
TD68_RS00680	COG5578	integral membrane protein
TD68_RS00685	COG2972	Histidine kinase
TD68_RS00690	COG2207	Transcriptional regulator
TD68_RS00690	COG4753	response regulator
TD68_RS00695	COG1653	transport
TD68_RS00700	COG1175	transmembrane transport
TD68_RS00705	COG0395	ABC-type sugar transport system, permease component
TD68_RS00710	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
TD68_RS00715	COG2207	Transcriptional regulator
TD68_RS00720	COG2755	lipolytic protein G-D-S-L family
TD68_RS00730	COG5578	integral membrane protein
TD68_RS00735	COG3401	FG-GAP repeat protein
TD68_RS00740	COG3401	FG-GAP repeat protein
TD68_RS00745	COG2755	lipolytic protein G-D-S-L family
TD68_RS00750	COG1874	Beta-galactosidase
TD68_RS00760	COG1653	transport
TD68_RS00765	COG4209	transmembrane transport
TD68_RS00770	COG0395	ABC-type sugar transport system, permease component
TD68_RS00775	COG1486	melibiose metabolic process
TD68_RS00780	COG2323	membrane
TD68_RS00785	COG2329	Antibiotic biosynthesis monooxygenase
TD68_RS00790	COG0346	lactoylglutathione lyase activity
TD68_RS00795	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS00800	COG0196	riboflavin kinase activity
TD68_RS00805	COG0670	Belongs to the BI1 family
TD68_RS00815	COG2124	cytochrome p450
TD68_RS00815	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TD68_RS00830	COG1131	(ABC) transporter
TD68_RS00840	COG1368	sulfuric ester hydrolase activity
TD68_RS00845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TD68_RS00850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS00855	COG1442	glycosyl transferase family 8
TD68_RS00860	COG1216	Glycosyl transferase, family 2
TD68_RS00865	COG1442	glycosyl transferase family 8
TD68_RS00870	COG2223	nitrite transmembrane transporter activity
TD68_RS00875	COG0531	amino acid
TD68_RS00880	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS00885	COG0840	transmembrane signaling receptor activity
TD68_RS00890	COG0463	Glycosyl transferase, family 2
TD68_RS00895	COG0488	(ABC) transporter
TD68_RS00900	COG0789	Transcriptional regulator
TD68_RS00905	COG2814	Major facilitator Superfamily
TD68_RS00910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS00915	COG0488	(ABC) transporter
TD68_RS00920	COG0513	Belongs to the DEAD box helicase family
TD68_RS00925	COG0457	Tetratricopeptide repeat
TD68_RS00930	COG2130	NADP-dependent
TD68_RS00935	COG1120	ATPase activity
TD68_RS00940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS00945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS00950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
TD68_RS00965	COG3866	Pectate lyase
TD68_RS00975	COG0471	metal ion transport
TD68_RS00995	COG3290	protein histidine kinase activity
TD68_RS01000	COG4565	transcriptional regulatory protein
TD68_RS01005	COG3181	Tripartite tricarboxylate transporter family receptor
TD68_RS01010	COG2851	Citrate transporter
TD68_RS01015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_RS01020	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
TD68_RS01025	COG1254	Belongs to the acylphosphatase family
TD68_RS01030	COG2258	MOSC domain
TD68_RS01040	COG0024	Methionine aminopeptidase
TD68_RS01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS01045	COG1263	PTS System
TD68_RS01050	COG1368	sulfuric ester hydrolase activity
TD68_RS01060	COG1115	amino acid carrier protein
TD68_RS01065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS01065	COG1263	PTS System
TD68_RS01070	COG0366	Alpha amylase catalytic
TD68_RS01075	COG2188	Transcriptional regulator
TD68_RS01080	COG0778	Nitroreductase
TD68_RS01085	COG0737	Belongs to the 5'-nucleotidase family
TD68_RS01090	COG0693	protein deglycase activity
TD68_RS01095	COG1609	Transcriptional regulator
TD68_RS01100	COG2814	Major facilitator Superfamily
TD68_RS01105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TD68_RS01115	COG2814	Major facilitator Superfamily
TD68_RS01120	COG4840	Belongs to the UPF0435 family
TD68_RS01125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD68_RS01130	COG4980	gas vesicle protein
TD68_RS01135	COG1295	ribonuclease BN
TD68_RS01140	COG0477	Major facilitator Superfamily
TD68_RS01145	COG0387	Pfam Sodium calcium exchanger
TD68_RS01155	COG0668	transmembrane transport
TD68_RS01160	COG0535	radical SAM domain protein
TD68_RS01170	COG0726	polysaccharide deacetylase
TD68_RS01175	COG2084	Dehydrogenase
TD68_RS01185	COG0598	Magnesium transport protein CorA
TD68_RS01190	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TD68_RS01200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TD68_RS01205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TD68_RS01210	COG4637	Psort location Cytoplasmic, score
TD68_RS01215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD68_RS01220	COG0022	dehydrogenase e1 component
TD68_RS01225	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_RS01230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD68_RS01235	COG3284	Transcriptional regulator
TD68_RS01245	COG1742	UPF0060 membrane protein
TD68_RS01265	COG4842	Belongs to the WXG100 family
TD68_RS01270	COG1486	melibiose metabolic process
TD68_RS01275	COG1737	Transcriptional regulator
TD68_RS01280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS01280	COG1263	PTS System
TD68_RS01285	COG5434	Belongs to the glycosyl hydrolase 28 family
TD68_RS01290	COG1132	(ABC) transporter
TD68_RS01295	COG1132	(ABC) transporter
TD68_RS01300	COG2259	Doxx family
TD68_RS01305	COG2514	catechol 2,3-dioxygenase activity
TD68_RS01310	COG0842	Transport permease protein
TD68_RS01315	COG1695	Transcriptional regulator
TD68_RS01320	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
TD68_RS01325	COG2732	(Barnase) inhibitor
TD68_RS01330	COG0604	alcohol dehydrogenase
TD68_RS01335	COG2318	DinB family
TD68_RS01340	COG2814	Major facilitator Superfamily
TD68_RS01345	COG1846	Transcriptional regulator
TD68_RS01350	COG0392	lysyltransferase activity
TD68_RS01350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
TD68_RS01355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_RS01360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS01365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS01370	COG0384	phenazine biosynthesis protein PhzF
TD68_RS01375	COG0778	Nitroreductase
TD68_RS01385	COG1090	epimerase
TD68_RS01390	COG2137	regulation of response to DNA damage stimulus
TD68_RS01400	COG2814	Major facilitator Superfamily
TD68_RS01415	COG3103	Sh3 type 3 domain protein
TD68_RS01420	COG5658	integral membrane protein
TD68_RS01425	COG0596	Alpha beta hydrolase
TD68_RS01430	COG0463	Glycosyl transferase, family 2
TD68_RS01435	COG4485	Bacterial membrane protein, YfhO
TD68_RS01440	COG1988	membrane-bound metal-dependent
TD68_RS01445	COG1194	a g-specific adenine glycosylase
TD68_RS01455	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS01470	COG3557	Belongs to the UPF0374 family
TD68_RS01475	COG1132	(ABC) transporter
TD68_RS01480	COG4129	membrane
TD68_RS01485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TD68_RS01490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TD68_RS01495	COG0735	belongs to the Fur family
TD68_RS01605	COG1063	alcohol dehydrogenase
TD68_RS01610	COG5577	PFAM Coat F domain
TD68_RS01620	COG4326	sporulation control protein
TD68_RS01625	COG3340	Belongs to the peptidase S51 family
TD68_RS01630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TD68_RS01645	COG1116	anion transmembrane transporter activity
TD68_RS01650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD68_RS01655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD68_RS01665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TD68_RS01675	COG1476	TRANSCRIPTIONal
TD68_RS01685	COG3382	B3 4 domain protein
TD68_RS01690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TD68_RS01700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TD68_RS01705	COG0789	Transcriptional regulator
TD68_RS01710	COG1664	Polymer-forming cytoskeletal
TD68_RS01715	COG1664	Polymer-forming cytoskeletal
TD68_RS01720	COG2766	serine protein kinase
TD68_RS01725	COG2718	Belongs to the UPF0229 family
TD68_RS01730	COG1846	Transcriptional regulator
TD68_RS01735	COG1566	PFAM secretion protein HlyD family protein
TD68_RS01740	COG2814	Major facilitator Superfamily
TD68_RS01745	COG0655	NAD(P)H dehydrogenase (quinone) activity
TD68_RS01760	COG1725	Transcriptional regulator
TD68_RS01765	COG1131	(ABC) transporter
TD68_RS01770	COG1131	(ABC) transporter
TD68_RS01775	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD68_RS01780	COG1278	Cold shock
TD68_RS01785	COG1464	Belongs to the NlpA lipoprotein family
TD68_RS01790	COG3706	GGDEF domain
TD68_RS01795	COG1823	symporter activity
TD68_RS01820	COG4085	toxin activity
TD68_RS01820	COG1525	nuclease
TD68_RS01820	COG0737	Belongs to the 5'-nucleotidase family
TD68_RS01825	COG3764	Sortase (surface protein transpeptidase)
TD68_RS01830	COG0564	pseudouridine synthase activity
TD68_RS01840	COG0517	IMP dehydrogenase activity
TD68_RS01845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TD68_RS01850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TD68_RS01850	COG3153	acetyltransferase
TD68_RS01860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD68_RS01865	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
TD68_RS01870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TD68_RS01875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TD68_RS01880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TD68_RS01885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TD68_RS01890	COG4585	Histidine kinase
TD68_RS01890	COG2203	Gaf domain
TD68_RS01895	COG2197	response regulator
TD68_RS01900	COG0431	NADPH-dependent FMN reductase
TD68_RS01915	COG0791	NLP P60 protein
TD68_RS01915	COG1388	LysM domain
TD68_RS01920	COG1959	2 iron, 2 sulfur cluster binding
TD68_RS01925	COG0668	transmembrane transport
TD68_RS01930	COG2719	SpoVR family
TD68_RS01935	COG1785	Belongs to the alkaline phosphatase family
TD68_RS01940	COG1388	LysM domain
TD68_RS01940	COG0791	NLP P60 protein
TD68_RS01945	COG0583	DNA-binding transcription factor activity
TD68_RS01950	COG0372	Belongs to the citrate synthase family
TD68_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS01960	COG0531	amino acid
TD68_RS01965	COG0733	neurotransmitter:sodium symporter activity
TD68_RS01970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS01975	COG0456	acetyltransferase
TD68_RS01980	COG0833	amino acid
TD68_RS01985	COG4187	Peptidase family M20/M25/M40
TD68_RS01990	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS01995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_RS02010	COG1595	DNA-templated transcription, initiation
TD68_RS02015	COG0667	Aldo Keto reductase
TD68_RS02020	COG0204	Acyl-transferase
TD68_RS02025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_RS02030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS02035	COG1253	flavin adenine dinucleotide binding
TD68_RS02040	COG0789	Transcriptional regulator
TD68_RS02045	COG1253	flavin adenine dinucleotide binding
TD68_RS02050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TD68_RS02055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TD68_RS02060	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_RS02065	COG0668	transmembrane transport
TD68_RS02070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TD68_RS02075	COG0726	polysaccharide deacetylase
TD68_RS02080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_RS02085	COG1757	Na H antiporter
TD68_RS02090	COG0589	response to stress
TD68_RS02095	COG1132	(ABC) transporter
TD68_RS02100	COG1132	(ABC) transporter
TD68_RS02105	COG0702	epimerase
TD68_RS02120	COG0189	ligase activity
TD68_RS02125	COG0189	ligase activity
TD68_RS02135	COG4399	Belongs to the UPF0754 family
TD68_RS02145	COG4335	DNA alkylation repair
TD68_RS02150	COG0561	phosphatase activity
TD68_RS02155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TD68_RS02165	COG0475	glutathione-regulated potassium exporter activity
TD68_RS02170	COG0490	domain, Protein
TD68_RS02180	COG1024	Enoyl-CoA hydratase
TD68_RS02190	COG4152	abc transporter atp-binding protein
TD68_RS02195	COG1668	transmembrane transport
TD68_RS02200	COG0420	3'-5' exonuclease activity
TD68_RS02205	COG4717	serine-type aminopeptidase activity
TD68_RS02210	COG3481	metal-dependent phosphohydrolase, HD sub domain
TD68_RS02220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD68_RS02255	COG4980	gas vesicle protein
TD68_RS02270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TD68_RS02275	COG0537	adenosine 5'-monophosphoramidase activity
TD68_RS02280	COG1131	(ABC) transporter
TD68_RS02285	COG4473	ABC transporter
TD68_RS02295	COG1473	amidohydrolase
TD68_RS02300	COG3069	C4-dicarboxylate transmembrane transporter activity
TD68_RS02305	COG2329	Antibiotic biosynthesis monooxygenase
TD68_RS02310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_RS02315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TD68_RS02320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TD68_RS02325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TD68_RS02330	COG1309	transcriptional regulator
TD68_RS02335	COG1511	domain protein
TD68_RS02340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD68_RS02350	COG1363	Peptidase, m42
TD68_RS02355	COG1301	dicarboxylic acid transport
TD68_RS02360	COG1234	tRNA 3'-trailer cleavage
TD68_RS02365	COG0095	Lipoate-protein ligase
TD68_RS02370	COG0702	epimerase
TD68_RS02375	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_RS02385	COG0501	Belongs to the peptidase M48B family
TD68_RS02390	COG1404	Belongs to the peptidase S8 family
TD68_RS02395	COG0456	acetyltransferase
TD68_RS02400	COG0604	alcohol dehydrogenase
TD68_RS02405	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
TD68_RS02410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS02415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS02420	COG0406	alpha-ribazole phosphatase activity
TD68_RS02425	COG0183	Belongs to the thiolase family
TD68_RS02430	COG1960	acyl-CoA dehydrogenase activity
TD68_RS02435	COG2084	Dehydrogenase
TD68_RS02440	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS02445	COG1024	Enoyl-CoA hydratase
TD68_RS02455	COG0840	transmembrane signaling receptor activity
TD68_RS02460	COG0723	plastoquinol--plastocyanin reductase activity
TD68_RS02460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_RS02465	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS02475	COG4903	ComK protein
TD68_RS02485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_RS02500	COG0398	Pfam SNARE associated Golgi protein
TD68_RS02505	COG0681	Belongs to the peptidase S26 family
TD68_RS02510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TD68_RS02515	COG1846	Transcriptional regulator
TD68_RS02520	COG3180	Ammonia monooxygenase
TD68_RS02530	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
TD68_RS02535	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TD68_RS02540	COG1074	ATP-dependent DNA helicase activity
TD68_RS02545	COG0420	3'-5' exonuclease activity
TD68_RS02550	COG0419	ATPase involved in DNA repair
TD68_RS02555	COG1403	HNH endonuclease
TD68_RS02590	COG2311	Membrane
TD68_RS02600	COG5337	Spore coat protein CotH
TD68_RS02605	COG0179	Fumarylacetoacetate (FAA) hydrolase
TD68_RS02615	COG1404	Belongs to the peptidase S8 family
TD68_RS02625	COG0367	asparagine synthase
TD68_RS02630	COG1562	ergosterol biosynthetic process
TD68_RS02635	COG0534	Mate efflux family protein
TD68_RS02640	COG2207	Transcriptional regulator
TD68_RS02640	COG1917	Cupin 2, conserved barrel domain protein
TD68_RS02645	COG0109	protoheme IX farnesyltransferase activity
TD68_RS02650	COG1609	Transcriptional regulator
TD68_RS02655	COG0673	inositol 2-dehydrogenase activity
TD68_RS02660	COG2318	DinB family
TD68_RS02665	COG1279	arginine transmembrane transporter activity
TD68_RS02670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS02675	COG1357	PFAM Pentapeptide repeats (8 copies)
TD68_RS02685	COG2267	carboxylic ester hydrolase activity
TD68_RS02690	COG0529	Catalyzes the synthesis of activated sulfate
TD68_RS02695	COG2046	Belongs to the sulfate adenylyltransferase family
TD68_RS02700	COG0175	sulfate reduction
TD68_RS02705	COG2045	Belongs to the ComB family
TD68_RS02710	COG1809	phosphosulfolactate synthase activity
TD68_RS02715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS02720	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_RS02725	COG2814	Major facilitator Superfamily
TD68_RS02735	COG2153	protein acetylation
TD68_RS02740	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TD68_RS02740	COG0646	methionine synthase
TD68_RS02750	COG2996	Protein conserved in bacteria
TD68_RS02765	COG1307	EDD domain protein, DegV family
TD68_RS02770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS02785	COG0561	phosphatase activity
TD68_RS02790	COG1073	alpha beta
TD68_RS02795	COG2151	metal-sulfur cluster biosynthetic enzyme
TD68_RS02800	COG0277	FAD linked oxidase domain protein
TD68_RS02805	COG2271	Major facilitator Superfamily
TD68_RS02810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TD68_RS02815	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TD68_RS02825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TD68_RS02830	COG0505	Belongs to the CarA family
TD68_RS02835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TD68_RS02840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TD68_RS02855	COG2267	carboxylic ester hydrolase activity
TD68_RS02865	COG1744	ABC transporter substrate-binding protein PnrA-like
TD68_RS02880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD68_RS02885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD68_RS02890	COG5504	Zn-dependent protease
TD68_RS02900	COG4608	Belongs to the ABC transporter superfamily
TD68_RS02910	COG0601	transmembrane transport
TD68_RS02915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD68_RS02925	COG0180	Tryptophanyl-tRNA synthetase
TD68_RS02930	COG4166	transmembrane transport
TD68_RS02935	COG0601	transmembrane transport
TD68_RS02940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD68_RS02945	COG0444	Belongs to the ABC transporter superfamily
TD68_RS02950	COG4608	Belongs to the ABC transporter superfamily
TD68_RS02955	COG2814	Major facilitator Superfamily
TD68_RS02965	COG0456	acetyltransferase
TD68_RS02970	COG1393	Belongs to the ArsC family
TD68_RS02975	COG0861	Integral membrane protein TerC family
TD68_RS02980	COG4862	establishment of competence for transformation
TD68_RS02985	COG4469	Competence protein
TD68_RS02990	COG1164	Oligoendopeptidase f
TD68_RS03000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TD68_RS03010	COG0741	lytic transglycosylase activity
TD68_RS03015	COG4116	CYTH
TD68_RS03025	COG2357	RelA SpoT domain protein
TD68_RS03030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TD68_RS03035	COG0564	pseudouridine synthase activity
TD68_RS03045	COG0475	glutathione-regulated potassium exporter activity
TD68_RS03045	COG0569	domain protein
TD68_RS03050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
TD68_RS03055	COG0352	thiamine-phosphate diphosphorylase activity
TD68_RS03060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_RS03065	COG2104	thiamine diphosphate biosynthetic process
TD68_RS03070	COG2022	thiamine diphosphate biosynthetic process
TD68_RS03075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD68_RS03080	COG0351	phosphomethylpyrimidine kinase
TD68_RS03085	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TD68_RS03135	COG0210	DNA helicase
TD68_RS03160	COG2153	protein acetylation
TD68_RS03170	COG2382	esterase
TD68_RS03175	COG0626	cystathionine gamma-synthase activity
TD68_RS03180	COG0626	cystathionine gamma-synthase activity
TD68_RS03185	COG5505	Protein of unknown function (DUF819)
TD68_RS03245	COG3209	COG3209 Rhs family protein
TD68_RS03250	COG1285	pathogenesis
TD68_RS03270	COG0726	polysaccharide deacetylase
TD68_RS03280	COG2205	protein histidine kinase activity
TD68_RS03290	COG3383	formate dehydrogenase (NAD+) activity
TD68_RS03295	COG2427	Protein of unknown function (DUF1641)
TD68_RS03305	COG1051	belongs to the nudix hydrolase family
TD68_RS03315	COG2124	cytochrome p450
TD68_RS03320	COG1819	glycosyl
TD68_RS03340	COG1587	Uroporphyrinogen-III synthase
TD68_RS03345	COG0390	transport system, permease component
TD68_RS03350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD68_RS03355	COG0697	spore germination
TD68_RS03360	COG4297	protein containing double-stranded beta helix domain
TD68_RS03370	COG1252	NADH dehydrogenase
TD68_RS03375	COG1904	glucuronate isomerase
TD68_RS03380	COG2211	Major facilitator Superfamily
TD68_RS03385	COG1609	Transcriptional regulator
TD68_RS03390	COG0246	Mannitol dehydrogenase
TD68_RS03395	COG2721	sulfolactate sulfo-lyase activity
TD68_RS03400	COG0730	response to heat
TD68_RS03405	COG2318	DinB family
TD68_RS03410	COG0457	Tetratricopeptide repeat
TD68_RS03420	COG1388	LysM domain
TD68_RS03420	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS03420	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD68_RS03430	COG4195	phage-related replication protein
TD68_RS03435	COG2856	Zn peptidase
TD68_RS03440	COG1396	sequence-specific DNA binding
TD68_RS03450	COG1522	sequence-specific DNA binding
TD68_RS03455	COG1484	DNA-dependent DNA replication
TD68_RS03470	COG1595	DNA-templated transcription, initiation
TD68_RS03475	COG5484	DNA packaging
TD68_RS03475	COG3728	DNA packaging
TD68_RS03480	COG1783	phage Terminase large subunit
TD68_RS03485	COG5518	Phage portal protein
TD68_RS03490	COG0338	D12 class N6 adenine-specific DNA methyltransferase
TD68_RS03495	COG4653	Phage capsid family
TD68_RS03540	COG5412	phage tail tape measure protein
TD68_RS03540	COG3953	SLT domain
TD68_RS03545	COG1652	LysM domain
TD68_RS03550	COG4193	domain, Protein
TD68_RS03565	COG3628	GPW Gp25 family protein
TD68_RS03570	COG3299	homolog of phage Mu protein gp47
TD68_RS03575	COG3778	Protein conserved in bacteria
TD68_RS03615	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS03615	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD68_RS03630	COG0306	phosphate transporter
TD68_RS03635	COG1392	Phosphate transport regulator
TD68_RS03640	COG0531	amino acid
TD68_RS03645	COG0346	lactoylglutathione lyase activity
TD68_RS03650	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TD68_RS03655	COG0463	Glycosyl transferase, family 2
TD68_RS03665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_RS03670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD68_RS03675	COG2362	D-Aminopeptidase
TD68_RS03680	COG0601	transmembrane transport
TD68_RS03685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TD68_RS03690	COG0444	Belongs to the ABC transporter superfamily
TD68_RS03695	COG4166	transmembrane transport
TD68_RS03700	COG1619	proteins homologs of microcin C7 resistance protein MccF
TD68_RS03705	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_RS03710	COG0791	NLP P60 protein
TD68_RS03715	COG4608	Belongs to the ABC transporter superfamily
TD68_RS03720	COG2706	6-phosphogluconolactonase activity
TD68_RS03725	COG1834	amidinotransferase
TD68_RS03730	COG1607	acyl-coa hydrolase
TD68_RS03735	COG2323	membrane
TD68_RS03740	COG1695	Transcriptional regulator
TD68_RS03755	COG2318	DinB family
TD68_RS03760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS03765	COG2076	Multidrug Resistance protein
TD68_RS03770	COG2076	Multidrug Resistance protein
TD68_RS03775	COG0788	formyltetrahydrofolate deformylase activity
TD68_RS03780	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TD68_RS03785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TD68_RS03790	COG1764	response to oxidative stress
TD68_RS03795	COG1846	Transcriptional regulator
TD68_RS03800	COG1764	response to oxidative stress
TD68_RS03815	COG0457	Tetratricopeptide repeat
TD68_RS03815	COG0463	Glycosyl transferase, family 2
TD68_RS03825	COG0590	tRNA wobble adenosine to inosine editing
TD68_RS03835	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TD68_RS03840	COG1404	Belongs to the peptidase S8 family
TD68_RS03845	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS03850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TD68_RS03855	COG1122	ATPase activity
TD68_RS03860	COG4721	ABC-type cobalt transport system, permease component
TD68_RS03870	COG0745	RESPONSE REGULATOR receiver
TD68_RS03875	COG5002	protein histidine kinase activity
TD68_RS03875	COG3850	Histidine kinase
TD68_RS03880	COG3212	peptidase
TD68_RS03885	COG3212	peptidase
TD68_RS03890	COG2239	Acts as a magnesium transporter
TD68_RS03895	COG0789	Transcriptional regulator
TD68_RS03905	COG1846	Transcriptional regulator
TD68_RS03910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD68_RS03915	COG0726	polysaccharide deacetylase
TD68_RS03920	COG1408	metallophosphoesterase
TD68_RS03935	COG0463	Glycosyl transferase, family 2
TD68_RS03940	COG3285	dna ligase
TD68_RS03940	COG1793	dna ligase
TD68_RS03945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
TD68_RS03950	COG5001	Diguanylate cyclase
TD68_RS03950	COG3300	MHYT domain
TD68_RS03955	COG5001	Diguanylate cyclase
TD68_RS03955	COG3300	MHYT domain
TD68_RS03960	COG3300	MHYT domain
TD68_RS03960	COG5001	Diguanylate cyclase
TD68_RS03965	COG0586	Pfam SNARE associated Golgi protein
TD68_RS03970	COG0861	Integral membrane protein TerC family
TD68_RS03975	COG1191	sigma factor activity
TD68_RS03995	COG0501	Belongs to the peptidase M48B family
TD68_RS04000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD68_RS04005	COG2323	membrane
TD68_RS04010	COG3594	Acyltransferase
TD68_RS04015	COG5002	protein histidine kinase activity
TD68_RS04020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TD68_RS04030	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
TD68_RS04035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TD68_RS04040	COG0436	Aminotransferase
TD68_RS04045	COG1850	ribulose-bisphosphate carboxylase activity
TD68_RS04055	COG0235	Class ii aldolase
TD68_RS04060	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
TD68_RS04065	COG3339	Conserved Protein
TD68_RS04080	COG3852	Histidine kinase
TD68_RS04085	COG1846	Transcriptional regulator
TD68_RS04090	COG1360	Flagellar Motor Protein
TD68_RS04095	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TD68_RS04100	COG0542	response to heat
TD68_RS04105	COG3949	Membrane
TD68_RS04120	COG0720	synthase
TD68_RS04125	COG0602	queuosine metabolic process
TD68_RS04130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TD68_RS04135	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS04145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS04150	COG4873	Protein conserved in bacteria
TD68_RS04160	COG3773	Cell wall hydrolase
TD68_RS04165	COG2244	polysaccharide biosynthetic process
TD68_RS04170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS04175	COG2217	Heavy metal translocating P-type atpase
TD68_RS04185	COG0006	proline dipeptidase activity
TD68_RS04190	COG1609	Transcriptional regulator
TD68_RS04195	COG3711	transcriptional antiterminator
TD68_RS04200	COG1263	PTS System
TD68_RS04200	COG2190	(PTS) system
TD68_RS04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS04205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS04210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TD68_RS04220	COG1533	DNA photolyase activity
TD68_RS04225	COG0456	acetyltransferase
TD68_RS04230	COG0840	transmembrane signaling receptor activity
TD68_RS04235	COG2084	Dehydrogenase
TD68_RS04240	COG2340	Cysteine-rich secretory protein family
TD68_RS04245	COG0768	penicillin binding
TD68_RS04250	COG4191	Histidine kinase
TD68_RS04255	COG0436	Aminotransferase
TD68_RS04260	COG0835	chemotaxis
TD68_RS04260	COG0784	Response regulator, receiver
TD68_RS04270	COG2814	Major facilitator Superfamily
TD68_RS04275	COG1376	ErfK ybiS ycfS ynhG family protein
TD68_RS04280	COG1408	metallophosphoesterase
TD68_RS04285	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS04290	COG2200	EAL domain
TD68_RS04295	COG3546	catalase activity
TD68_RS04300	COG4703	Protein of unknown function (DUF1797)
TD68_RS04305	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
TD68_RS04315	COG0517	IMP dehydrogenase activity
TD68_RS04320	COG0583	DNA-binding transcription factor activity
TD68_RS04325	COG0716	FMN binding
TD68_RS04335	COG0716	FMN binding
TD68_RS04340	COG2171	N-acyltransferase activity
TD68_RS04345	COG1473	amidohydrolase
TD68_RS04355	COG0668	transmembrane transport
TD68_RS04360	COG0450	alkyl hydroperoxide reductase
TD68_RS04365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS04380	COG0746	molybdenum cofactor guanylyltransferase activity
TD68_RS04385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TD68_RS04390	COG0303	'Molybdopterin
TD68_RS04395	COG1763	Mo-molybdopterin cofactor biosynthetic process
TD68_RS04400	COG0314	molybdopterin synthase activity
TD68_RS04405	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
TD68_RS04410	COG1132	(ABC) transporter
TD68_RS04415	COG1132	(ABC) transporter
TD68_RS04425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TD68_RS04430	COG1136	(ABC) transporter
TD68_RS04435	COG0577	efflux transmembrane transporter activity
TD68_RS04440	COG1349	DNA-binding transcription factor activity
TD68_RS04445	COG1105	Belongs to the carbohydrate kinase PfkB family
TD68_RS04450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_RS04450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS04450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_RS04455	COG0681	Belongs to the peptidase S26 family
TD68_RS04465	COG0488	(ABC) transporter
TD68_RS04470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD68_RS04475	COG2309	aminopeptidase activity
TD68_RS04480	COG1077	Cell shape determining protein MreB Mrl
TD68_RS04485	COG2002	toxin-antitoxin pair type II binding
TD68_RS04490	COG3852	Histidine kinase
TD68_RS04495	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
TD68_RS04495	COG2105	PFAM AIG2 family protein
TD68_RS04500	COG0569	domain protein
TD68_RS04505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TD68_RS04510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TD68_RS04520	COG0561	phosphatase activity
TD68_RS04525	COG0242	peptide deformylase activity
TD68_RS04535	COG0497	DNA recombination
TD68_RS04540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD68_RS04545	COG0022	dehydrogenase e1 component
TD68_RS04550	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_RS04555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD68_RS04560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS04570	COG1982	Orn Lys Arg decarboxylase major
TD68_RS04575	COG4476	Belongs to the UPF0223 family
TD68_RS04580	COG4493	Belongs to the UPF0637 family
TD68_RS04590	COG0483	inositol monophosphate 1-phosphatase activity
TD68_RS04600	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
TD68_RS04620	COG1595	DNA-templated transcription, initiation
TD68_RS04640	COG1217	gtp-binding protein TYPA
TD68_RS04650	COG4896	Protein conserved in bacteria
TD68_RS04660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TD68_RS04665	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TD68_RS04670	COG2066	Belongs to the glutaminase family
TD68_RS04675	COG4838	Belongs to the UPF0358 family
TD68_RS04680	COG0772	Belongs to the SEDS family
TD68_RS04685	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
TD68_RS04690	COG1612	heme a metabolic process
TD68_RS04700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TD68_RS04700	COG2010	Cytochrome c
TD68_RS04705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TD68_RS04710	COG1845	cytochrome c oxidase, subunit III
TD68_RS04715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
TD68_RS04720	COG3336	cytochrome c oxidase
TD68_RS04730	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
TD68_RS04735	COG2340	Cysteine-rich secretory protein family
TD68_RS04755	COG3679	Belongs to the UPF0342 family
TD68_RS04760	COG4471	UPF0298 protein
TD68_RS04765	COG0742	ribosomal rna small subunit methyltransferase
TD68_RS04770	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TD68_RS04775	COG3314	Sporulation integral membrane protein YlbJ
TD68_RS04780	COG1752	Esterase of the alpha-beta hydrolase superfamily
TD68_RS04785	COG3480	Lon protease (S16) C-terminal proteolytic domain
TD68_RS04790	COG1323	Belongs to the UPF0348 family
TD68_RS04795	COG1399	metal-binding, possibly nucleic acid-binding protein
TD68_RS04815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD68_RS04820	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
TD68_RS04825	COG2001	Belongs to the MraZ family
TD68_RS04830	COG0275	rRNA processing
TD68_RS04835	COG4839	cell division protein FtsL
TD68_RS04840	COG0768	penicillin binding
TD68_RS04845	COG0768	penicillin binding
TD68_RS04850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TD68_RS04855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TD68_RS04860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TD68_RS04865	COG0772	Belongs to the SEDS family
TD68_RS04870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD68_RS04875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TD68_RS04880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TD68_RS04885	COG3879	Bacterial protein of unknown function (DUF881)
TD68_RS04890	COG3879	Bacterial protein of unknown function (DUF881)
TD68_RS04895	COG3856	small basic protein
TD68_RS04900	COG0849	cell division
TD68_RS04905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TD68_RS04910	COG1404	Belongs to the peptidase S8 family
TD68_RS04910	COG4412	M6 family metalloprotease domain protein
TD68_RS04920	COG1191	sigma factor activity
TD68_RS04925	COG1191	sigma factor activity
TD68_RS04930	COG1119	ATPase activity
TD68_RS04935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_RS04940	COG1873	PFAM PRC-barrel domain
TD68_RS04945	COG1496	oxidoreductase activity
TD68_RS04950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TD68_RS04955	COG1799	cell septum assembly
TD68_RS04960	COG0762	integral membrane protein
TD68_RS04965	COG2302	S4 RNA-binding domain
TD68_RS04970	COG3599	regulation of cell shape
TD68_RS04975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TD68_RS04980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD68_RS04985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TD68_RS04990	COG0564	pseudouridine synthase activity
TD68_RS05000	COG2233	PERMEase
TD68_RS05005	COG0540	Belongs to the ATCase OTCase family
TD68_RS05010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TD68_RS05015	COG0505	Belongs to the CarA family
TD68_RS05020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TD68_RS05025	COG0543	2 iron, 2 sulfur cluster binding
TD68_RS05030	COG0167	dihydroorotate dehydrogenase activity
TD68_RS05035	COG0284	orotidine-5'-phosphate decarboxylase activity
TD68_RS05040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TD68_RS05045	COG0175	sulfate reduction
TD68_RS05050	COG0306	phosphate transporter
TD68_RS05055	COG2046	Belongs to the sulfate adenylyltransferase family
TD68_RS05060	COG0529	Catalyzes the synthesis of activated sulfate
TD68_RS05065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TD68_RS05070	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
TD68_RS05075	COG1648	precorrin-2 dehydrogenase activity
TD68_RS05080	COG1293	RNA-binding protein homologous to eukaryotic snRNP
TD68_RS05085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TD68_RS05090	COG1561	YicC-like family, N-terminal region
TD68_RS05100	COG0194	GDP metabolic process
TD68_RS05105	COG1758	RNA polymerase activity
TD68_RS05110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TD68_RS05115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TD68_RS05120	COG0242	peptide deformylase activity
TD68_RS05125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TD68_RS05130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TD68_RS05130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TD68_RS05140	COG0631	protein serine/threonine phosphatase activity
TD68_RS05145	COG2815	serine threonine protein kinase
TD68_RS05145	COG0515	serine threonine protein kinase
TD68_RS05150	COG1162	GTPase activity
TD68_RS05155	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TD68_RS05160	COG1564	THIamine pyrophosphokinase
TD68_RS05170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TD68_RS05175	COG1302	Protein conserved in bacteria
TD68_RS05180	COG1461	Dihydroxyacetone kinase
TD68_RS05185	COG1760	l-serine dehydratase
TD68_RS05190	COG1760	l-serine dehydratase
TD68_RS05195	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TD68_RS05200	COG2050	protein possibly involved in aromatic compounds catabolism
TD68_RS05200	COG1349	DNA-binding transcription factor activity
TD68_RS05210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD68_RS05215	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS05225	COG0571	ribonuclease III activity
TD68_RS05230	COG1196	nuclear chromosome segregation
TD68_RS05235	COG0552	protein localization to endoplasmic reticulum
TD68_RS05240	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
TD68_RS05245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TD68_RS05250	COG0228	four-way junction DNA binding
TD68_RS05255	COG1837	Belongs to the UPF0109 family
TD68_RS05265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TD68_RS05280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TD68_RS05285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TD68_RS05295	COG2257	FlhB HrpN YscU SpaS Family
TD68_RS05305	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TD68_RS05310	COG0758	DNA mediated transformation
TD68_RS05315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TD68_RS05320	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TD68_RS05325	COG4974	Belongs to the 'phage' integrase family
TD68_RS05330	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TD68_RS05335	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TD68_RS05345	COG1815	bacterial-type flagellum-dependent cell motility
TD68_RS05350	COG1558	bacterial-type flagellum-dependent cell motility
TD68_RS05355	COG1677	Flagellar hook-basal body complex protein FliE
TD68_RS05360	COG1766	The M ring may be actively involved in energy transduction
TD68_RS05365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD68_RS05370	COG1317	bacterial-type flagellum organization
TD68_RS05375	COG1157	protein secretion by the type III secretion system
TD68_RS05380	COG2882	bacterial-type flagellum organization
TD68_RS05385	COG3334	PFAM MgtE intracellular
TD68_RS05390	COG3144	bacterial-type flagellum assembly
TD68_RS05395	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TD68_RS05400	COG4786	Flagellar basal body rod
TD68_RS05405	COG1582	Flagellar protein (FlbD)
TD68_RS05410	COG1580	Controls the rotational direction of flagella during chemotaxis
TD68_RS05415	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD68_RS05420	COG1776	CheC inhibitor of MCP methylation
TD68_RS05420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TD68_RS05425	COG2201	protein-glutamate methylesterase activity
TD68_RS05430	COG3190	flagellar
TD68_RS05435	COG1338	Plays a role in the flagellum-specific transport system
TD68_RS05440	COG1987	bacterial-type flagellum assembly
TD68_RS05445	COG1684	flagellar biosynthetic protein fliR
TD68_RS05450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TD68_RS05455	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TD68_RS05460	COG1419	protein localization to endoplasmic reticulum
TD68_RS05465	COG0455	bacterial-type flagellum organization
TD68_RS05470	COG2201	protein-glutamate methylesterase activity
TD68_RS05475	COG2198	Histidine kinase
TD68_RS05475	COG0643	Histidine kinase
TD68_RS05480	COG0835	chemotaxis
TD68_RS05485	COG1776	CheC inhibitor of MCP methylation
TD68_RS05490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
TD68_RS05495	COG1191	sigma factor activity
TD68_RS05510	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TD68_RS05515	COG0528	UMP kinase activity
TD68_RS05520	COG0233	cytoplasmic translational termination
TD68_RS05525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TD68_RS05530	COG4589	Belongs to the CDS family
TD68_RS05535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TD68_RS05540	COG0750	zinc metalloprotease
TD68_RS05545	COG0442	prolyl-tRNA aminoacylation
TD68_RS05550	COG2176	DNA-directed DNA polymerase activity
TD68_RS05555	COG0779	Required for maturation of 30S ribosomal subunits
TD68_RS05560	COG0195	Participates in both transcription termination and antitermination
TD68_RS05565	COG2740	Nucleic-acid-binding protein implicated in transcription termination
TD68_RS05570	COG1358	cellular component organization or biogenesis
TD68_RS05575	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TD68_RS05580	COG1550	Protein conserved in bacteria
TD68_RS05585	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TD68_RS05590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TD68_RS05595	COG0196	riboflavin kinase activity
TD68_RS05605	COG1185	polyribonucleotide nucleotidyltransferase activity
TD68_RS05610	COG0726	polysaccharide deacetylase
TD68_RS05615	COG0612	Peptidase, M16
TD68_RS05620	COG1873	PFAM PRC-barrel domain
TD68_RS05625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TD68_RS05630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TD68_RS05635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TD68_RS05640	COG0527	aspartate kinase activity
TD68_RS05650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TD68_RS05655	COG0740	serine-type endopeptidase activity
TD68_RS05665	COG1674	ftsk spoiiie
TD68_RS05665	COG4980	gas vesicle protein
TD68_RS05670	COG2188	Transcriptional regulator
TD68_RS05675	COG2814	Major facilitator Superfamily
TD68_RS05680	COG0612	Peptidase, M16
TD68_RS05685	COG0612	Peptidase, M16
TD68_RS05690	COG0300	oxidoreductase activity
TD68_RS05705	COG1426	Protein conserved in bacteria
TD68_RS05710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TD68_RS05715	COG1058	Belongs to the CinA family
TD68_RS05715	COG1546	Belongs to the CinA family
TD68_RS05720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TD68_RS05725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD68_RS05735	COG1692	metallophosphoesterase
TD68_RS05740	COG2359	stage V sporulation protein S
TD68_RS05745	COG1063	alcohol dehydrogenase
TD68_RS05750	COG0156	8-amino-7-oxononanoate synthase activity
TD68_RS05765	COG4550	Control of competence regulator ComK, YlbF/YmcA
TD68_RS05775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TD68_RS05780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TD68_RS05795	COG3226	Transcriptional regulator
TD68_RS05800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_RS05805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD68_RS05810	COG3321	synthase
TD68_RS05815	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TD68_RS05815	COG2070	2-Nitropropane dioxygenase
TD68_RS05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_RS05825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TD68_RS05830	COG3425	synthase
TD68_RS05835	COG1024	Enoyl-CoA hydratase
TD68_RS05840	COG1024	Enoyl-CoA hydratase
TD68_RS05845	COG0300	oxidoreductase activity
TD68_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS05845	COG3321	synthase
TD68_RS05845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS05845	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_RS05850	COG4221	oxidoreductase activity
TD68_RS05850	COG3321	synthase
TD68_RS05850	COG0300	oxidoreductase activity
TD68_RS05850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_RS05855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_RS05855	COG3321	synthase
TD68_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS05855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS05855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS05860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS05860	COG4221	oxidoreductase activity
TD68_RS05860	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS05860	COG3321	synthase
TD68_RS05865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TD68_RS05865	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
TD68_RS05865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TD68_RS05865	COG3321	synthase
TD68_RS05870	COG2124	cytochrome p450
TD68_RS05880	COG1404	Belongs to the peptidase S8 family
TD68_RS05890	COG4195	phage-related replication protein
TD68_RS05895	COG1764	response to oxidative stress
TD68_RS05905	COG2076	Multidrug Resistance protein
TD68_RS05925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TD68_RS05950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TD68_RS05955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TD68_RS05960	COG4112	unkown
TD68_RS05965	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_RS05970	COG0464	growth
TD68_RS05975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TD68_RS05980	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
TD68_RS05985	COG0789	Transcriptional regulator
TD68_RS05990	COG0174	glutamine synthetase
TD68_RS06005	COG0456	acetyltransferase
TD68_RS06010	COG1525	nuclease
TD68_RS06015	COG4282	regulation of fungal-type cell wall biogenesis
TD68_RS06020	COG5444	nuclease activity
TD68_RS06035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS06055	COG0346	lactoylglutathione lyase activity
TD68_RS06075	COG2273	Hydrolase Family 16
TD68_RS06095	COG3391	amine dehydrogenase activity
TD68_RS06110	COG0657	acetylesterase activity
TD68_RS06120	COG1011	Hydrolase
TD68_RS06125	COG0667	Aldo Keto reductase
TD68_RS06145	COG2318	DinB family
TD68_RS06150	COG2367	Beta-lactamase
TD68_RS06155	COG1388	LysM domain
TD68_RS06155	COG4641	Protein conserved in bacteria
TD68_RS06160	COG1388	LysM domain
TD68_RS06165	COG3858	chitin binding
TD68_RS06170	COG2720	vancomycin resistance protein
TD68_RS06175	COG5553	Cysteine dioxygenase type I
TD68_RS06185	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS06205	COG0456	acetyltransferase
TD68_RS06210	COG4978	Transcriptional regulator
TD68_RS06210	COG0789	Transcriptional regulator
TD68_RS06215	COG2030	dehydratase
TD68_RS06230	COG2135	peptidase activity
TD68_RS06245	COG0457	Tetratricopeptide repeat
TD68_RS06260	COG1131	(ABC) transporter
TD68_RS06305	COG4195	phage-related replication protein
TD68_RS06310	COG3619	membrane
TD68_RS06330	COG4195	phage-related replication protein
TD68_RS06355	COG5577	PFAM Coat F domain
TD68_RS06365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TD68_RS06370	COG1388	LysM domain
TD68_RS06375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TD68_RS06380	COG4224	UPF0291 protein
TD68_RS06385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TD68_RS06395	COG3763	UPF0154 protein
TD68_RS06405	COG0785	Cytochrome C biogenesis protein
TD68_RS06410	COG2201	protein-glutamate methylesterase activity
TD68_RS06415	COG4846	Membrane protein involved in cytochrome C biogenesis
TD68_RS06425	COG0071	Belongs to the small heat shock protein (HSP20) family
TD68_RS06440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TD68_RS06445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS06460	COG0824	Thioesterase
TD68_RS06470	COG4841	protein insertion into membrane
TD68_RS06475	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TD68_RS06480	COG1832	CoA-binding protein
TD68_RS06485	COG0187	DNA topoisomerase II activity
TD68_RS06490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TD68_RS06500	COG1115	amino acid carrier protein
TD68_RS06510	COG0745	RESPONSE REGULATOR receiver
TD68_RS06520	COG3507	Belongs to the glycosyl hydrolase 43 family
TD68_RS06525	COG2246	polysaccharide biosynthetic process
TD68_RS06535	COG0586	Pfam SNARE associated Golgi protein
TD68_RS06540	COG2404	hydrolase activity, acting on ester bonds
TD68_RS06545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TD68_RS06550	COG1024	Enoyl-CoA hydratase
TD68_RS06555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TD68_RS06560	COG0511	ligase activity, forming carbon-carbon bonds
TD68_RS06565	COG0439	Biotin carboxylase
TD68_RS06570	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_RS06575	COG1960	acyl-CoA dehydrogenase activity
TD68_RS06580	COG1649	PFAM Uncharacterised BCR, COG1649
TD68_RS06590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
TD68_RS06590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS06595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS06600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS06605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS06610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS06615	COG1017	nitric oxide dioxygenase activity
TD68_RS06615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TD68_RS06620	COG2027	D-alanyl-D-alanine carboxypeptidase
TD68_RS06625	COG2017	converts alpha-aldose to the beta-anomer
TD68_RS06635	COG2207	Transcriptional regulator
TD68_RS06635	COG3708	Transcriptional regulator
TD68_RS06640	COG0457	Tetratricopeptide repeat
TD68_RS06650	COG1388	LysM domain
TD68_RS06650	COG5632	N-Acetylmuramoyl-L-alanine amidase
TD68_RS06650	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS06660	COG0582	viral genome integration into host DNA
TD68_RS06665	COG0166	Belongs to the GPI family
TD68_RS06670	COG0405	Gamma-glutamyltransferase
TD68_RS06680	COG0604	alcohol dehydrogenase
TD68_RS06685	COG0493	'glutamate synthase
TD68_RS06690	COG0067	glutamate synthase
TD68_RS06690	COG0069	glutamate synthase activity
TD68_RS06690	COG0070	glutamate synthase
TD68_RS06695	COG0583	DNA-binding transcription factor activity
TD68_RS06700	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TD68_RS06755	COG3331	DNA recombination
TD68_RS06765	COG0252	asparaginase activity
TD68_RS06770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TD68_RS06775	COG0251	oxidation-reduction process
TD68_RS06810	COG0756	dUTP diphosphatase activity
TD68_RS06855	COG0693	protein deglycase activity
TD68_RS06990	COG3655	Transcriptional regulator
TD68_RS07005	COG0582	viral genome integration into host DNA
TD68_RS07085	COG3655	Transcriptional regulator
TD68_RS07130	COG1395	domain, Protein
TD68_RS07150	COG0776	regulation of translation
TD68_RS07280	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_RS07310	COG0741	lytic transglycosylase activity
TD68_RS07310	COG0739	heme binding
TD68_RS07310	COG1196	nuclear chromosome segregation
TD68_RS07315	COG1196	nuclear chromosome segregation
TD68_RS07315	COG0741	lytic transglycosylase activity
TD68_RS07315	COG0739	heme binding
TD68_RS07325	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_RS07355	COG4282	regulation of fungal-type cell wall biogenesis
TD68_RS07360	COG0693	protein deglycase activity
TD68_RS07365	COG0300	oxidoreductase activity
TD68_RS07370	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
TD68_RS07375	COG2318	DinB family
TD68_RS07380	COG2814	Major facilitator Superfamily
TD68_RS07385	COG1070	Carbohydrate kinase
TD68_RS07390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TD68_RS07395	COG0243	molybdopterin cofactor binding
TD68_RS07410	COG1309	transcriptional regulator
TD68_RS07415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_RS07420	COG0662	Cupin 2, conserved barrel domain protein
TD68_RS07420	COG2207	Transcriptional regulator
TD68_RS07425	COG1309	transcriptional regulator
TD68_RS07430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_RS07435	COG3708	Transcriptional regulator
TD68_RS07440	COG2378	regulation of single-species biofilm formation
TD68_RS07450	COG0640	Transcriptional regulator
TD68_RS07455	COG0741	lytic transglycosylase activity
TD68_RS07460	COG2322	membrane
TD68_RS07475	COG3239	Fatty acid desaturase
TD68_RS07480	COG4585	Histidine kinase
TD68_RS07485	COG2197	response regulator
TD68_RS07495	COG3584	3D domain protein
TD68_RS07495	COG1388	LysM domain
TD68_RS07500	COG0514	ATP-dependent DNA helicase (RecQ)
TD68_RS07505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD68_RS07510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD68_RS07525	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS07530	COG1657	PFAM Prenyltransferase squalene oxidase
TD68_RS07535	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD68_RS07540	COG0733	neurotransmitter:sodium symporter activity
TD68_RS07545	COG0385	Bile acid
TD68_RS07550	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_RS07555	COG0567	Dehydrogenase, E1 component
TD68_RS07560	COG4548	von Willebrand factor, type A
TD68_RS07565	COG0714	Associated with various cellular activities
TD68_RS07570	COG2032	superoxide dismutase activity
TD68_RS07575	COG0791	NLP P60 protein
TD68_RS07575	COG1388	LysM domain
TD68_RS07580	COG1819	glycosyl
TD68_RS07585	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TD68_RS07590	COG0534	Mate efflux family protein
TD68_RS07595	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS07600	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_RS07605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_RS07615	COG2962	Rard protein
TD68_RS07635	COG2318	DinB family
TD68_RS07645	COG1942	4-Oxalocrotonate Tautomerase
TD68_RS07650	COG1733	regulation of RNA biosynthetic process
TD68_RS07655	COG0778	Nitroreductase
TD68_RS07660	COG0400	carboxylic ester hydrolase activity
TD68_RS07665	COG0346	lactoylglutathione lyase activity
TD68_RS07675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_RS07680	COG0793	Belongs to the peptidase S41A family
TD68_RS07680	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS07685	COG2226	methyltransferase
TD68_RS07695	COG1876	peptidase activity
TD68_RS07700	COG0813	purine-nucleoside phosphorylase activity
TD68_RS07710	COG0671	phosphoesterase, PA-phosphatase related
TD68_RS07735	COG1509	lysine 2,3-aminomutase activity
TD68_RS07740	COG0456	acetyltransferase
TD68_RS07745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_RS07750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TD68_RS07755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
TD68_RS07760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD68_RS07770	COG0456	acetyltransferase
TD68_RS07775	COG0463	Glycosyl transferase, family 2
TD68_RS07790	COG4641	Protein conserved in bacteria
TD68_RS07795	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
TD68_RS07800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TD68_RS07805	COG0366	Alpha amylase catalytic
TD68_RS07810	COG3397	chitin binding
TD68_RS07820	COG3655	Transcriptional regulator
TD68_RS07825	COG3739	integral membrane protein
TD68_RS07830	COG3708	Transcriptional regulator
TD68_RS07830	COG2207	Transcriptional regulator
TD68_RS07850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TD68_RS07855	COG1846	Transcriptional regulator
TD68_RS07860	COG0534	Mate efflux family protein
TD68_RS07870	COG4698	Protein conserved in bacteria
TD68_RS07875	COG2755	lipolytic protein G-D-S-L family
TD68_RS07880	COG1999	signal sequence binding
TD68_RS07890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TD68_RS07895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TD68_RS07900	COG1272	protein, Hemolysin III
TD68_RS07905	COG0204	Acyl-transferase
TD68_RS07910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TD68_RS07920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TD68_RS07930	COG2136	Putative SAM-dependent methyltransferase
TD68_RS07930	COG2521	methyltransferase
TD68_RS07945	COG1413	lyase activity
TD68_RS07950	COG1418	mRNA catabolic process
TD68_RS07955	COG0386	Belongs to the glutathione peroxidase family
TD68_RS07960	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TD68_RS07965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TD68_RS07970	COG1278	Cold shock
TD68_RS07990	COG0328	RNA-DNA hybrid ribonuclease activity
TD68_RS07995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
TD68_RS08000	COG0328	RNA-DNA hybrid ribonuclease activity
TD68_RS08010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD68_RS08020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD68_RS08025	COG1755	Isoprenylcysteine carboxyl methyltransferase
TD68_RS08030	COG3424	synthase
TD68_RS08035	COG2233	PERMEase
TD68_RS08040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TD68_RS08045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TD68_RS08055	COG0800	Aldolase
TD68_RS08060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_RS08065	COG1609	Transcriptional regulator
TD68_RS08070	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
TD68_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS08080	COG1199	ATP-dependent helicase activity
TD68_RS08090	COG0116	Belongs to the methyltransferase superfamily
TD68_RS08105	COG3359	exonuclease
TD68_RS08110	COG1111	helicase
TD68_RS08110	COG1205	dead DEAH box helicase
TD68_RS08115	COG2190	(PTS) system
TD68_RS08120	COG0071	Belongs to the small heat shock protein (HSP20) family
TD68_RS08155	COG3331	DNA recombination
TD68_RS08160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_RS08160	COG4499	WXG100 protein secretion system (Wss), protein YukC
TD68_RS08170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TD68_RS08175	COG3935	DnaD domain protein
TD68_RS08180	COG0017	Asparaginyl-tRNA synthetase
TD68_RS08185	COG0436	Aminotransferase
TD68_RS08190	COG5353	protein conserved in bacteria
TD68_RS08195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TD68_RS08195	COG1199	ATP-dependent helicase activity
TD68_RS08200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TD68_RS08205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TD68_RS08210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TD68_RS08220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TD68_RS08220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TD68_RS08225	COG0617	tRNA 3'-terminal CCA addition
TD68_RS08230	COG0438	transferase activity, transferring glycosyl groups
TD68_RS08235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_RS08250	COG1694	Mazg nucleotide pyrophosphohydrolase
TD68_RS08255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS08260	COG2140	Oxalate decarboxylase
TD68_RS08270	COG4347	Protein of unknown function (DUF1405)
TD68_RS08275	COG2010	Cytochrome c
TD68_RS08275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TD68_RS08280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TD68_RS08285	COG0723	plastoquinol--plastocyanin reductase activity
TD68_RS08295	COG5582	Belongs to the UPF0302 family
TD68_RS08300	COG0457	Tetratricopeptide repeat
TD68_RS08305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TD68_RS08310	COG0287	Prephenate dehydrogenase
TD68_RS08315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TD68_RS08320	COG0159	tryptophan synthase activity
TD68_RS08340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TD68_RS08345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TD68_RS08350	COG4401	Chorismate mutase type I
TD68_RS08355	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TD68_RS08365	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TD68_RS08370	COG0105	UTP biosynthetic process
TD68_RS08375	COG0142	geranyltranstransferase activity
TD68_RS08385	COG0142	geranyltranstransferase activity
TD68_RS08395	COG0302	gtp cyclohydrolase
TD68_RS08400	COG0776	regulation of translation
TD68_RS08405	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
TD68_RS08420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TD68_RS08425	COG1160	GTP binding
TD68_RS08445	COG1304	FMN binding
TD68_RS08450	COG0539	negative regulation of cytoplasmic translation
TD68_RS08455	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TD68_RS08460	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
TD68_RS08465	COG2959	enzyme of heme biosynthesis
TD68_RS08470	COG3773	Cell wall hydrolase
TD68_RS08470	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS08475	COG2339	peptidase activity
TD68_RS08480	COG0492	ferredoxin-NADP+ reductase activity
TD68_RS08485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_RS08490	COG4862	establishment of competence for transformation
TD68_RS08495	COG1408	metallophosphoesterase
TD68_RS08505	COG1388	LysM domain
TD68_RS08510	COG1266	CAAX protease self-immunity
TD68_RS08515	COG0514	ATP-dependent DNA helicase (RecQ)
TD68_RS08520	COG4955	Helix-turn-helix domain
TD68_RS08525	COG1141	Ferredoxin
TD68_RS08530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
TD68_RS08535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TD68_RS08540	COG0710	3-dehydroquinate dehydratase activity
TD68_RS08550	COG1595	DNA-templated transcription, initiation
TD68_RS08555	COG5002	protein histidine kinase activity
TD68_RS08560	COG0745	RESPONSE REGULATOR receiver
TD68_RS08565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TD68_RS08570	COG1333	cytochrome c biogenesis protein
TD68_RS08575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS08580	COG1187	pseudouridine synthase activity
TD68_RS08585	COG0700	Nucleoside recognition
TD68_RS08590	COG2715	membrane protein required for spore maturation
TD68_RS08595	COG1686	Belongs to the peptidase S11 family
TD68_RS08605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TD68_RS08610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TD68_RS08615	COG1547	Domain of unknown function (DUF309)
TD68_RS08620	COG0456	acetyltransferase
TD68_RS08625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TD68_RS08630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TD68_RS08630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TD68_RS08635	COG0307	riboflavin synthase, alpha
TD68_RS08640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TD68_RS08640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TD68_RS08655	COG0681	Belongs to the peptidase S26 family
TD68_RS08660	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
TD68_RS08665	COG1278	Cold shock
TD68_RS08670	COG0823	Involved in the tonB-independent uptake of proteins
TD68_RS08680	COG3420	alginic acid biosynthetic process
TD68_RS08690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TD68_RS08700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TD68_RS08735	COG0322	excinuclease ABC activity
TD68_RS08740	COG3584	3D domain protein
TD68_RS08820	COG1428	Deoxynucleoside kinase
TD68_RS08830	COG1435	thymidine kinase activity
TD68_RS08845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TD68_RS09045	COG0457	Tetratricopeptide repeat
TD68_RS09070	COG4086	secreted protein
TD68_RS09075	COG0019	diaminopimelate decarboxylase activity
TD68_RS09080	COG0697	spore germination
TD68_RS09095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TD68_RS09115	COG1191	sigma factor activity
TD68_RS09120	COG2172	sigma factor antagonist activity
TD68_RS09125	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS09130	COG1686	Belongs to the peptidase S11 family
TD68_RS09135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TD68_RS09140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TD68_RS09145	COG4974	Belongs to the 'phage' integrase family
TD68_RS09155	COG0735	belongs to the Fur family
TD68_RS09160	COG1300	Membrane
TD68_RS09170	COG0281	malic enzyme
TD68_RS09175	COG1757	Na H antiporter
TD68_RS09180	COG1027	Aspartate ammonia-lyase
TD68_RS09185	COG0252	asparaginase activity
TD68_RS09190	COG1396	sequence-specific DNA binding
TD68_RS09195	COG1379	DNA repair
TD68_RS09200	COG0494	nUDIX hydrolase
TD68_RS09210	COG0667	Aldo Keto reductase
TD68_RS09220	COG1073	alpha beta
TD68_RS09230	COG4918	Iron-sulphur cluster biosynthesis
TD68_RS09235	COG0456	acetyltransferase
TD68_RS09235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
TD68_RS09245	COG0456	acetyltransferase
TD68_RS09255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_RS09265	COG0628	permease
TD68_RS09270	COG2211	Major facilitator Superfamily
TD68_RS09275	COG0346	lactoylglutathione lyase activity
TD68_RS09280	COG1072	(Pantothenic acid kinase))
TD68_RS09285	COG3048	D-serine ammonia-lyase activity
TD68_RS09290	COG0300	oxidoreductase activity
TD68_RS09295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_RS09300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD68_RS09305	COG4187	Peptidase family M20/M25/M40
TD68_RS09310	COG1902	pentaerythritol trinitrate reductase activity
TD68_RS09315	COG0596	Alpha beta hydrolase
TD68_RS09325	COG1234	tRNA 3'-trailer cleavage
TD68_RS09330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TD68_RS09335	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TD68_RS09340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_RS09350	COG0706	membrane insertase activity
TD68_RS09355	COG3361	conserved protein (COG2071)
TD68_RS09360	COG2195	Cleaves the N-terminal amino acid of tripeptides
TD68_RS09365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TD68_RS09370	COG0346	lactoylglutathione lyase activity
TD68_RS09375	COG1376	ErfK ybiS ycfS ynhG family protein
TD68_RS09380	COG4129	membrane
TD68_RS09385	COG1126	abc transporter atp-binding protein
TD68_RS09390	COG0765	amino acid transport
TD68_RS09395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_RS09405	COG1597	lipid kinase activity
TD68_RS09415	COG0508	dehydrogenase complex catalyzes the overall conversion of
TD68_RS09420	COG0022	dehydrogenase e1 component
TD68_RS09425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TD68_RS09430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TD68_RS09435	COG3426	butyrate kinase activity
TD68_RS09440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_RS09445	COG0280	phosphate acetyltransferase
TD68_RS09450	COG3829	transcription factor binding
TD68_RS09450	COG3290	protein histidine kinase activity
TD68_RS09460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TD68_RS09465	COG2079	MmgE PrpD family protein
TD68_RS09475	COG1960	acyl-CoA dehydrogenase activity
TD68_RS09480	COG1250	3-hydroxyacyl-CoA dehydrogenase
TD68_RS09485	COG0183	Belongs to the thiolase family
TD68_RS09490	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_RS09495	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_RS09505	COG1902	pentaerythritol trinitrate reductase activity
TD68_RS09515	COG0745	RESPONSE REGULATOR receiver
TD68_RS09520	COG0750	zinc metalloprotease
TD68_RS09525	COG0497	DNA recombination
TD68_RS09530	COG1438	arginine binding
TD68_RS09535	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
TD68_RS09540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TD68_RS09545	COG0142	geranyltranstransferase activity
TD68_RS09550	COG1722	exodeoxyribonuclease VII activity
TD68_RS09555	COG1570	exodeoxyribonuclease VII activity
TD68_RS09560	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TD68_RS09565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TD68_RS09570	COG1302	Protein conserved in bacteria
TD68_RS09575	COG0439	Biotin carboxylase
TD68_RS09580	COG0511	ligase activity, forming carbon-carbon bonds
TD68_RS09620	COG3854	ATPases associated with a variety of cellular activities
TD68_RS09630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TD68_RS09635	COG0006	proline dipeptidase activity
TD68_RS09640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TD68_RS09650	COG3872	metal-dependent enzyme
TD68_RS09660	COG1752	Esterase of the alpha-beta hydrolase superfamily
TD68_RS09665	COG1321	iron dependent repressor
TD68_RS09670	COG0095	Lipoate-protein ligase
TD68_RS09675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD68_RS09680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TD68_RS09685	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TD68_RS09690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TD68_RS09695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD68_RS09710	COG1396	sequence-specific DNA binding
TD68_RS09720	COG0681	Belongs to the peptidase S26 family
TD68_RS09745	COG4940	Competence protein ComGF
TD68_RS09755	COG4970	Tfp pilus assembly protein FimT
TD68_RS09760	COG4537	Required for transformation and DNA binding
TD68_RS09765	COG1459	type II secretion system
TD68_RS09770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TD68_RS09775	COG0598	Magnesium transport protein CorA
TD68_RS09780	COG1253	flavin adenine dinucleotide binding
TD68_RS09785	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS09795	COG1393	Belongs to the ArsC family
TD68_RS09805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_RS09815	COG0011	TIGRFAM Protein of
TD68_RS09825	COG2866	Carboxypeptidase
TD68_RS09830	COG1368	sulfuric ester hydrolase activity
TD68_RS09835	COG1940	carbohydrate kinase activity
TD68_RS09840	COG4483	Protein conserved in bacteria
TD68_RS09845	COG0705	Rhomboid family
TD68_RS09845	COG0457	Tetratricopeptide repeat
TD68_RS09850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TD68_RS09855	COG0438	transferase activity, transferring glycosyl groups
TD68_RS09870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TD68_RS09875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD68_RS09880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TD68_RS09885	COG0581	inorganic phosphate transmembrane transporter activity
TD68_RS09890	COG0573	inorganic phosphate transmembrane transporter activity
TD68_RS09895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TD68_RS09900	COG0768	penicillin binding
TD68_RS09905	COG0477	Major facilitator Superfamily
TD68_RS09910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TD68_RS09915	COG2839	Protein conserved in bacteria
TD68_RS09920	COG5521	maltodextrose utilization protein MalA
TD68_RS09925	COG1388	LysM domain
TD68_RS09935	COG4709	membrane
TD68_RS09940	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
TD68_RS09945	COG0735	belongs to the Fur family
TD68_RS09950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS09960	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TD68_RS09965	COG0513	Belongs to the DEAD box helicase family
TD68_RS09975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TD68_RS09980	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TD68_RS09985	COG2384	SAM-dependent methyltransferase
TD68_RS09990	COG2010	Cytochrome c
TD68_RS09995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TD68_RS10000	COG0358	DNA primase activity
TD68_RS10005	COG1671	Belongs to the UPF0178 family
TD68_RS10010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
TD68_RS10015	COG0517	IMP dehydrogenase activity
TD68_RS10020	COG0751	glycine-tRNA ligase activity
TD68_RS10025	COG0752	glycyl-tRNA synthetase alpha subunit
TD68_RS10030	COG1381	Involved in DNA repair and RecF pathway recombination
TD68_RS10035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TD68_RS10040	COG0295	cytidine deaminase activity
TD68_RS10045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TD68_RS10055	COG1480	7TM receptor with intracellular HD hydrolase
TD68_RS10060	COG1702	phosphate starvation-inducible protein PhoH
TD68_RS10065	COG0561	phosphatase activity
TD68_RS10080	COG4864	UPF0365 protein
TD68_RS10085	COG1030	water channel activity
TD68_RS10090	COG1610	YqeY-like protein
TD68_RS10100	COG1283	sodium-dependent phosphate transmembrane transporter activity
TD68_RS10105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TD68_RS10110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TD68_RS10130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TD68_RS10135	COG1420	regulation of RNA biosynthetic process
TD68_RS10140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TD68_RS10145	COG0481	GTPase activity
TD68_RS10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_RS10170	COG1466	dna polymerase III delta subunit
TD68_RS10180	COG0658	competence protein
TD68_RS10180	COG2333	competence protein COMEC
TD68_RS10185	COG2131	deaminase
TD68_RS10190	COG1555	photosystem II stabilization
TD68_RS10190	COG1596	polysaccharide export
TD68_RS10195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TD68_RS10200	COG2226	methyltransferase
TD68_RS10205	COG0799	negative regulation of ribosome biogenesis
TD68_RS10210	COG1713	HD superfamily hydrolase involved in NAD metabolism
TD68_RS10215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TD68_RS10220	COG1534	Rna-binding protein
TD68_RS10225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TD68_RS10230	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TD68_RS10235	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TD68_RS10245	COG2755	lipolytic protein G-D-S-L family
TD68_RS10260	COG0398	Pfam SNARE associated Golgi protein
TD68_RS10270	COG5444	nuclease activity
TD68_RS10285	COG2732	(Barnase) inhibitor
TD68_RS10305	COG1725	Transcriptional regulator
TD68_RS10315	COG0583	DNA-binding transcription factor activity
TD68_RS10325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TD68_RS10345	COG0583	DNA-binding transcription factor activity
TD68_RS10350	COG2814	Major facilitator Superfamily
TD68_RS10355	COG2176	DNA-directed DNA polymerase activity
TD68_RS10360	COG2124	cytochrome p450
TD68_RS10360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TD68_RS10365	COG1309	transcriptional regulator
TD68_RS10370	COG2226	methyltransferase
TD68_RS10375	COG2116	formate transmembrane transporter activity
TD68_RS10380	COG5609	conserved protein (DUF2294)
TD68_RS10385	COG3383	formate dehydrogenase (NAD+) activity
TD68_RS10390	COG2427	Protein of unknown function (DUF1641)
TD68_RS10400	COG0626	cystathionine gamma-synthase activity
TD68_RS10405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD68_RS10410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TD68_RS10415	COG2226	methyltransferase
TD68_RS10430	COG0768	penicillin binding
TD68_RS10435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TD68_RS10440	COG0572	uridine kinase
TD68_RS10445	COG0826	peptidase U32
TD68_RS10450	COG0826	peptidase U32
TD68_RS10455	COG4122	O-methyltransferase activity
TD68_RS10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TD68_RS10465	COG3906	Belongs to the UPF0473 family
TD68_RS10470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TD68_RS10475	COG4472	Bacterial protein of unknown function (DUF965)
TD68_RS10480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TD68_RS10485	COG0628	permease
TD68_RS10490	COG1126	abc transporter atp-binding protein
TD68_RS10495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_RS10500	COG0765	amino acid transport
TD68_RS10505	COG0765	amino acid transport
TD68_RS10515	COG3881	PFAM PRC-barrel domain
TD68_RS10520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TD68_RS10525	COG0457	Tetratricopeptide repeat
TD68_RS10530	COG0482	sulfurtransferase activity
TD68_RS10535	COG1104	cysteine desulfurase activity
TD68_RS10540	COG1959	2 iron, 2 sulfur cluster binding
TD68_RS10545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TD68_RS10550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TD68_RS10555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TD68_RS10565	COG3103	Sh3 type 3 domain protein
TD68_RS10565	COG4991	sh3 domain protein
TD68_RS10565	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_RS10570	COG1490	D-aminoacyl-tRNA deacylase activity
TD68_RS10575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TD68_RS10585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TD68_RS10585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TD68_RS10590	COG5416	Lipopolysaccharide assembly protein A domain
TD68_RS10595	COG0490	domain, Protein
TD68_RS10600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TD68_RS10600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TD68_RS10610	COG2244	polysaccharide biosynthetic process
TD68_RS10615	COG2323	membrane
TD68_RS10625	COG1862	Preprotein translocase
TD68_RS10635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TD68_RS10645	COG2255	four-way junction helicase activity
TD68_RS10660	COG2814	Major facilitator Superfamily
TD68_RS10665	COG2112	serine threonine protein kinase
TD68_RS10675	COG1115	amino acid carrier protein
TD68_RS10680	COG0217	transcriptional regulatory protein
TD68_RS10695	COG3394	polysaccharide catabolic process
TD68_RS10700	COG2188	Transcriptional regulator
TD68_RS10705	COG1486	melibiose metabolic process
TD68_RS10710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_RS10715	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD68_RS10720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_RS10730	COG1388	LysM domain
TD68_RS10735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TD68_RS10740	COG0157	Belongs to the NadC ModD family
TD68_RS10745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TD68_RS10750	COG1104	cysteine desulfurase activity
TD68_RS10755	COG1827	regulation of RNA biosynthetic process
TD68_RS10760	COG0077	Prephenate dehydratase
TD68_RS10765	COG4492	Belongs to the UPF0735 family
TD68_RS10770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TD68_RS10775	COG3290	protein histidine kinase activity
TD68_RS10780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TD68_RS10785	COG2868	ribosomal protein
TD68_RS10790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TD68_RS10795	COG1994	Peptidase M50
TD68_RS10800	COG0739	heme binding
TD68_RS10805	COG2894	cell division
TD68_RS10810	COG0850	regulation of cytokinetic process
TD68_RS10815	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
TD68_RS10825	COG1077	Cell shape determining protein MreB Mrl
TD68_RS10830	COG2003	Belongs to the UPF0758 family
TD68_RS10835	COG0424	maF-like protein
TD68_RS10845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TD68_RS10850	COG0285	dihydrofolate synthase activity
TD68_RS10855	COG0525	valine-tRNA ligase activity
TD68_RS10865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_RS10870	COG1388	LysM domain
TD68_RS10870	COG1388	LysM domain
TD68_RS10875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TD68_RS10880	COG0113	porphobilinogen synthase activity
TD68_RS10885	COG1587	Uroporphyrinogen-III synthase
TD68_RS10895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TD68_RS10900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TD68_RS10910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TD68_RS10915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TD68_RS10920	COG0470	DNA polymerase III
TD68_RS10920	COG1067	ATP-dependent peptidase activity
TD68_RS10930	COG0544	peptidyl-prolyl cis-trans isomerase activity
TD68_RS10935	COG0457	Tetratricopeptide repeat
TD68_RS10935	COG1477	protein flavinylation
TD68_RS10940	COG0066	3-isopropylmalate dehydratase activity
TD68_RS10945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TD68_RS10950	COG0473	3-isopropylmalate dehydrogenase activity
TD68_RS10955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TD68_RS10960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TD68_RS10965	COG0440	acetolactate synthase activity
TD68_RS10970	COG0028	Belongs to the TPP enzyme family
TD68_RS10975	COG0454	-acetyltransferase
TD68_RS10980	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
TD68_RS10990	COG0622	Phosphoesterase
TD68_RS10995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TD68_RS11000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TD68_RS11005	COG5401	PFAM Sporulation and spore germination
TD68_RS11010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TD68_RS11015	COG1846	Transcriptional regulator
TD68_RS11020	COG2197	response regulator
TD68_RS11025	COG0824	Thioesterase
TD68_RS11030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TD68_RS11035	COG1053	succinate dehydrogenase
TD68_RS11040	COG2009	succinate dehydrogenase
TD68_RS11045	COG1719	4-vinyl reductase, 4VR
TD68_RS11050	COG0527	aspartate kinase activity
TD68_RS11055	COG0322	excinuclease ABC activity
TD68_RS11060	COG3118	belongs to the thioredoxin family
TD68_RS11065	COG3534	alpha-L-arabinofuranosidase
TD68_RS11070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TD68_RS11075	COG2086	electron transfer activity
TD68_RS11080	COG1024	Enoyl-CoA hydratase
TD68_RS11085	COG1309	transcriptional regulator
TD68_RS11090	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_RS11095	COG3766	membrane
TD68_RS11100	COG1193	negative regulation of DNA recombination
TD68_RS11105	COG1796	DNA polymerase
TD68_RS11105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TD68_RS11110	COG1286	toxin biosynthetic process
TD68_RS11115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
TD68_RS11125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_RS11125	COG0072	phenylalanine-tRNA ligase activity
TD68_RS11130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TD68_RS11135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TD68_RS11145	COG3835	regulator
TD68_RS11150	COG0277	FAD linked oxidase domain protein
TD68_RS11155	COG0247	lactate metabolic process
TD68_RS11160	COG0346	lactoylglutathione lyase activity
TD68_RS11165	COG1966	Carbon starvation protein
TD68_RS11170	COG3534	alpha-L-arabinofuranosidase
TD68_RS11175	COG0395	ABC-type sugar transport system, permease component
TD68_RS11180	COG1175	transmembrane transport
TD68_RS11185	COG1653	transport
TD68_RS11190	COG0371	Dehydrogenase
TD68_RS11195	COG0647	UMP catabolic process
TD68_RS11200	COG0235	Class ii aldolase
TD68_RS11205	COG1069	ribulokinase activity
TD68_RS11210	COG2160	L-arabinose isomerase activity
TD68_RS11235	COG3507	Belongs to the glycosyl hydrolase 43 family
TD68_RS11240	COG1363	Peptidase, m42
TD68_RS11250	COG3326	Membrane
TD68_RS11255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TD68_RS11260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TD68_RS11265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TD68_RS11280	COG1346	cytolysis
TD68_RS11290	COG3279	Response regulator of the LytR AlgR family
TD68_RS11295	COG3275	phosphorelay sensor kinase activity
TD68_RS11300	COG1011	Hydrolase
TD68_RS11305	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TD68_RS11315	COG0398	Pfam SNARE associated Golgi protein
TD68_RS11320	COG1484	DNA-dependent DNA replication
TD68_RS11325	COG3611	Membrane attachment protein
TD68_RS11330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TD68_RS11335	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TD68_RS11340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TD68_RS11345	COG1733	regulation of RNA biosynthetic process
TD68_RS11350	COG2814	Major facilitator Superfamily
TD68_RS11355	COG0656	L-ascorbic acid biosynthetic process
TD68_RS11360	COG0237	dephospho-CoA kinase activity
TD68_RS11365	COG1971	Probably functions as a manganese efflux pump
TD68_RS11370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TD68_RS11375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD68_RS11375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TD68_RS11380	COG5002	protein histidine kinase activity
TD68_RS11385	COG0745	RESPONSE REGULATOR receiver
TD68_RS11395	COG0538	isocitrate dehydrogenase activity
TD68_RS11400	COG0372	Belongs to the citrate synthase family
TD68_RS11405	COG2707	UPF0756 membrane protein
TD68_RS11410	COG0628	permease
TD68_RS11415	COG3030	protein affecting phage T7 exclusion by the F plasmid
TD68_RS11420	COG0469	pyruvate kinase activity
TD68_RS11430	COG0825	malonyl-CoA metabolic process
TD68_RS11435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TD68_RS11440	COG0281	malic enzyme
TD68_RS11445	COG0587	DNA-directed DNA polymerase activity
TD68_RS11465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TD68_RS11475	COG4109	DRTGG domain
TD68_RS11480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TD68_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS11490	COG0165	Argininosuccinate lyase
TD68_RS11495	COG0137	argininosuccinate synthase activity
TD68_RS11500	COG0521	Mo-molybdopterin cofactor biosynthetic process
TD68_RS11510	COG0827	DNA restriction-modification system
TD68_RS11515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TD68_RS11520	COG3874	Sporulation protein YtfJ
TD68_RS11530	COG1714	RDD family
TD68_RS11535	COG0616	signal peptide processing
TD68_RS11540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TD68_RS11545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TD68_RS11550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD68_RS11560	COG0301	tRNA thio-modification
TD68_RS11565	COG1104	cysteine desulfurase activity
TD68_RS11570	COG1114	Component of the transport system for branched-chain amino acids
TD68_RS11575	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
TD68_RS11580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TD68_RS11585	COG1309	transcriptional regulator
TD68_RS11590	COG1956	GAF domain-containing protein
TD68_RS11595	COG2203	Gaf domain
TD68_RS11595	COG2199	diguanylate cyclase activity
TD68_RS11605	COG2267	carboxylic ester hydrolase activity
TD68_RS11620	COG1335	isochorismatase
TD68_RS11635	COG1846	Transcriptional regulator
TD68_RS11640	COG2259	Doxx family
TD68_RS11645	COG0346	lactoylglutathione lyase activity
TD68_RS11650	COG0400	carboxylic ester hydrolase activity
TD68_RS11660	COG0697	spore germination
TD68_RS11665	COG0583	DNA-binding transcription factor activity
TD68_RS11670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TD68_RS11675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TD68_RS11680	COG0454	-acetyltransferase
TD68_RS11685	COG0517	IMP dehydrogenase activity
TD68_RS11690	COG0123	including yeast histone deacetylase and acetoin utilization protein
TD68_RS11695	COG1360	Flagellar Motor Protein
TD68_RS11700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TD68_RS11705	COG1609	Transcriptional regulator
TD68_RS11710	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TD68_RS11710	COG1605	Chorismate mutase
TD68_RS11715	COG3118	belongs to the thioredoxin family
TD68_RS11720	COG4980	gas vesicle protein
TD68_RS11725	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
TD68_RS11735	COG1674	ftsk spoiiie
TD68_RS11740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_RS11745	COG4848	Belongs to the UPF0354 family
TD68_RS11750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS11760	COG1363	Peptidase, m42
TD68_RS11765	COG5584	Small secreted protein
TD68_RS11770	COG0281	malic enzyme
TD68_RS11775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TD68_RS11780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TD68_RS11790	COG0510	thiamine kinase activity
TD68_RS11795	COG1523	belongs to the glycosyl hydrolase 13 family
TD68_RS11800	COG1597	lipid kinase activity
TD68_RS11810	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TD68_RS11815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD68_RS11820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_RS11825	COG2252	PERMEase
TD68_RS11830	COG1349	DNA-binding transcription factor activity
TD68_RS11835	COG1187	pseudouridine synthase activity
TD68_RS11840	COG2244	polysaccharide biosynthetic process
TD68_RS11845	COG2081	HI0933 family
TD68_RS11850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TD68_RS11860	COG5578	integral membrane protein
TD68_RS11865	COG0673	inositol 2-dehydrogenase activity
TD68_RS11870	COG1653	transport
TD68_RS11875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
TD68_RS11880	COG4209	transmembrane transport
TD68_RS11890	COG1653	transport
TD68_RS11895	COG0395	ABC-type sugar transport system, permease component
TD68_RS11900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS11905	COG2124	cytochrome p450
TD68_RS11910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TD68_RS11920	COG0156	8-amino-7-oxononanoate synthase activity
TD68_RS11925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TD68_RS11930	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
TD68_RS11935	COG1073	alpha beta
TD68_RS11940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD68_RS11945	COG0495	leucyl-tRNA aminoacylation
TD68_RS11955	COG2202	Pas domain
TD68_RS11955	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS11960	COG2814	Major facilitator Superfamily
TD68_RS11965	COG2433	Pfam Transposase IS66
TD68_RS11970	COG0577	efflux transmembrane transporter activity
TD68_RS11975	COG1136	(ABC) transporter
TD68_RS11980	COG2205	protein histidine kinase activity
TD68_RS11985	COG0745	RESPONSE REGULATOR receiver
TD68_RS11990	COG0577	efflux transmembrane transporter activity
TD68_RS11995	COG1136	(ABC) transporter
TD68_RS12010	COG1131	(ABC) transporter
TD68_RS12015	COG1725	Transcriptional regulator
TD68_RS12030	COG0477	Major facilitator Superfamily
TD68_RS12035	COG1242	4 iron, 4 sulfur cluster binding
TD68_RS12040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TD68_RS12050	COG2267	carboxylic ester hydrolase activity
TD68_RS12055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
TD68_RS12060	COG1113	amino acid transport
TD68_RS12065	COG0367	asparagine synthase
TD68_RS12075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TD68_RS12085	COG1506	peptidase
TD68_RS12090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TD68_RS12095	COG1116	anion transmembrane transporter activity
TD68_RS12100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TD68_RS12105	COG0494	nUDIX hydrolase
TD68_RS12115	COG4824	toxin secretion phage lysis holin
TD68_RS12120	COG0783	Belongs to the Dps family
TD68_RS12140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TD68_RS12145	COG0288	reversible hydration of carbon dioxide
TD68_RS12150	COG0523	cobalamin synthesis protein
TD68_RS12160	COG1271	oxidase subunit
TD68_RS12165	COG1294	oxidase, subunit
TD68_RS12170	COG4305	rare lipoprotein A
TD68_RS12175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD68_RS12180	COG1321	iron dependent repressor
TD68_RS12180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD68_RS12185	COG1121	(ABC) transporter
TD68_RS12190	COG0803	Belongs to the bacterial solute-binding protein 9 family
TD68_RS12195	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_RS12200	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_RS12205	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TD68_RS12210	COG0596	Alpha beta hydrolase
TD68_RS12215	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TD68_RS12220	COG1169	isochorismate synthase
TD68_RS12225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TD68_RS12235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS12240	COG0438	transferase activity, transferring glycosyl groups
TD68_RS12250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_RS12255	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
TD68_RS12260	COG0058	SHG alpha-glucan phosphorylase activity
TD68_RS12265	COG0297	glycogen (starch) synthase activity
TD68_RS12270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TD68_RS12275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TD68_RS12280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TD68_RS12405	COG3859	Proton-coupled thiamine transporter YuaJ
TD68_RS12410	COG3764	Sortase (surface protein transpeptidase)
TD68_RS12425	COG2268	Band 7 protein
TD68_RS12430	COG1585	Membrane protein implicated in regulation of membrane protease activity
TD68_RS12435	COG2318	DinB family
TD68_RS12445	COG1454	alcohol dehydrogenase
TD68_RS12450	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS12455	COG1510	regulation of RNA biosynthetic process
TD68_RS12465	COG0569	domain protein
TD68_RS12470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TD68_RS12475	COG4682	membrane
TD68_RS12480	COG1705	Flagellar rod assembly protein muramidase FlgJ
TD68_RS12485	COG0477	Major facilitator Superfamily
TD68_RS12500	COG0628	permease
TD68_RS12505	COG0673	inositol 2-dehydrogenase activity
TD68_RS12510	COG0693	protein deglycase activity
TD68_RS12515	COG4806	L-rhamnose isomerase
TD68_RS12520	COG3254	rhamnose metabolic process
TD68_RS12525	COG1070	Carbohydrate kinase
TD68_RS12530	COG1349	DNA-binding transcription factor activity
TD68_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS12535	COG3347	Dehydrogenase
TD68_RS12540	COG0840	transmembrane signaling receptor activity
TD68_RS12545	COG0840	transmembrane signaling receptor activity
TD68_RS12550	COG0840	transmembrane signaling receptor activity
TD68_RS12555	COG0840	transmembrane signaling receptor activity
TD68_RS12570	COG2070	2-Nitropropane dioxygenase
TD68_RS12575	COG0432	Pfam Uncharacterised protein family UPF0047
TD68_RS12580	COG0366	Alpha amylase catalytic
TD68_RS12585	COG1253	flavin adenine dinucleotide binding
TD68_RS12590	COG2738	Putative neutral zinc metallopeptidase
TD68_RS12605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TD68_RS12620	COG0166	Belongs to the GPI family
TD68_RS12625	COG1979	alcohol dehydrogenase
TD68_RS12630	COG1979	alcohol dehydrogenase
TD68_RS12635	COG2155	Conserved Protein
TD68_RS12640	COG1098	S1 RNA binding domain
TD68_RS12645	COG0436	Aminotransferase
TD68_RS12650	COG1522	sequence-specific DNA binding
TD68_RS12655	COG2267	carboxylic ester hydrolase activity
TD68_RS12665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TD68_RS12670	COG2205	protein histidine kinase activity
TD68_RS12680	COG5018	Exonuclease
TD68_RS12690	COG2814	Major facilitator Superfamily
TD68_RS12695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_RS12700	COG3011	Protein conserved in bacteria
TD68_RS12710	COG3290	protein histidine kinase activity
TD68_RS12715	COG4565	transcriptional regulatory protein
TD68_RS12720	COG1744	ABC transporter substrate-binding protein PnrA-like
TD68_RS12725	COG3845	ABC transporter
TD68_RS12730	COG4603	Belongs to the binding-protein-dependent transport system permease family
TD68_RS12735	COG1079	Belongs to the binding-protein-dependent transport system permease family
TD68_RS12740	COG3493	citrate carrier protein
TD68_RS12750	COG2111	Na H antiporter
TD68_RS12750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TD68_RS12755	COG2111	Na H antiporter
TD68_RS12760	COG1006	Multisubunit Na H antiporter MnhC subunit
TD68_RS12765	COG0651	ATP synthesis coupled electron transport
TD68_RS12770	COG1863	multisubunit Na H antiporter MnhE subunit
TD68_RS12775	COG2212	antiporter activity
TD68_RS12780	COG1320	monovalent cation:proton antiporter activity
TD68_RS12785	COG2050	protein possibly involved in aromatic compounds catabolism
TD68_RS12790	COG2197	response regulator
TD68_RS12795	COG4585	Histidine kinase
TD68_RS12805	COG0142	geranyltranstransferase activity
TD68_RS12820	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
TD68_RS12825	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TD68_RS12830	COG1335	isochorismatase
TD68_RS12835	COG5506	Protein of unknown function (DUF1694)
TD68_RS12850	COG0628	permease
TD68_RS12860	COG1418	mRNA catabolic process
TD68_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS12875	COG1511	domain protein
TD68_RS12880	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
TD68_RS12880	COG2508	Transcriptional regulator
TD68_RS12885	COG0686	Belongs to the AlaDH PNT family
TD68_RS12890	COG5634	Uncharacterized conserved protein (DUF2278)
TD68_RS12895	COG3251	PFAM MbtH domain protein
TD68_RS12900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS12905	COG3433	isochorismatase activity
TD68_RS12905	COG1535	isochorismatase
TD68_RS12910	COG1021	2,3-dihydroxybenzoate-AMP ligase
TD68_RS12915	COG1169	isochorismate synthase
TD68_RS12920	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS12925	COG2819	hydrolase of the alpha beta superfamily
TD68_RS12940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TD68_RS12945	COG1268	BioY protein
TD68_RS12950	COG2056	Na+-H+ antiporter family
TD68_RS12955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TD68_RS12960	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TD68_RS12965	COG3584	3D domain protein
TD68_RS12975	COG1252	NADH dehydrogenase
TD68_RS12985	COG0516	GMP reductase activity
TD68_RS12990	COG0316	Belongs to the HesB IscA family
TD68_RS12995	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TD68_RS13000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD68_RS13005	COG4844	belongs to the
TD68_RS13010	COG1252	NADH dehydrogenase
TD68_RS13015	COG3479	Phenolic acid decarboxylase
TD68_RS13020	COG4837	Protein of unknown function (DUF1462)
TD68_RS13025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
TD68_RS13030	COG0823	Involved in the tonB-independent uptake of proteins
TD68_RS13030	COG1506	peptidase
TD68_RS13030	COG4946	Tricorn protease homolog
TD68_RS13035	COG0083	homoserine kinase activity
TD68_RS13040	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TD68_RS13045	COG0460	homoserine dehydrogenase
TD68_RS13050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TD68_RS13055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TD68_RS13060	COG0647	UMP catabolic process
TD68_RS13065	COG2445	Protein of unknown function DUF86
TD68_RS13070	COG4470	Protein conserved in bacteria
TD68_RS13085	COG0739	heme binding
TD68_RS13095	COG3377	Domain of unknown function (DUF1805)
TD68_RS13100	COG0737	Belongs to the 5'-nucleotidase family
TD68_RS13105	COG0730	response to heat
TD68_RS13110	COG1801	Protein of unknown function DUF72
TD68_RS13125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TD68_RS13130	COG2508	Transcriptional regulator
TD68_RS13135	COG2233	PERMEase
TD68_RS13140	COG1595	DNA-templated transcription, initiation
TD68_RS13195	COG1131	(ABC) transporter
TD68_RS13205	COG2080	2 iron, 2 sulfur cluster binding
TD68_RS13220	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
TD68_RS13225	COG2814	Major facilitator Superfamily
TD68_RS13230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TD68_RS13235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TD68_RS13240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TD68_RS13245	COG2356	endonuclease I
TD68_RS13255	COG3842	ATPase activity
TD68_RS13260	COG2188	Transcriptional regulator
TD68_RS13265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_RS13270	COG0395	ABC-type sugar transport system, permease component
TD68_RS13275	COG1175	transmembrane transport
TD68_RS13280	COG1653	transport
TD68_RS13285	COG2222	sugar isomerase
TD68_RS13290	COG0322	excinuclease ABC activity
TD68_RS13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TD68_RS13300	COG0719	Fe-S assembly protein
TD68_RS13305	COG0822	iron-sulfur transferase activity
TD68_RS13310	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TD68_RS13315	COG0719	Fe-S assembly protein
TD68_RS13320	COG0396	ATPase activity
TD68_RS13325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TD68_RS13330	COG1464	Belongs to the NlpA lipoprotein family
TD68_RS13335	COG2011	ABC-type metal ion transport system permease component
TD68_RS13340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TD68_RS13350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS13355	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
TD68_RS13365	COG0509	glycine decarboxylation via glycine cleavage system
TD68_RS13370	COG1393	Belongs to the ArsC family
TD68_RS13375	COG1960	acyl-CoA dehydrogenase activity
TD68_RS13380	COG0183	Belongs to the thiolase family
TD68_RS13385	COG1024	Enoyl-CoA hydratase
TD68_RS13385	COG1250	3-hydroxyacyl-CoA dehydrogenase
TD68_RS13400	COG5577	PFAM Coat F domain
TD68_RS13405	COG1846	Transcriptional regulator
TD68_RS13410	COG0477	Major facilitator Superfamily
TD68_RS13420	COG1120	ATPase activity
TD68_RS13435	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS13440	COG0783	Belongs to the Dps family
TD68_RS13445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_RS13450	COG0745	RESPONSE REGULATOR receiver
TD68_RS13455	COG2770	Histidine kinase
TD68_RS13455	COG2205	protein histidine kinase activity
TD68_RS13460	COG1309	transcriptional regulator
TD68_RS13465	COG0114	fumarate hydratase activity
TD68_RS13475	COG0697	spore germination
TD68_RS13480	COG0814	amino acid
TD68_RS13490	COG2197	response regulator
TD68_RS13495	COG4585	Histidine kinase
TD68_RS13500	COG4758	membrane
TD68_RS13505	COG3595	metallopeptidase activity
TD68_RS13510	COG1842	Phage shock protein A
TD68_RS13515	COG4758	membrane
TD68_RS13520	COG2814	Major facilitator Superfamily
TD68_RS13525	COG2096	Adenosyltransferase
TD68_RS13530	COG1120	ATPase activity
TD68_RS13535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS13540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS13550	COG3386	PFAM SMP-30 Gluconolaconase
TD68_RS13555	COG2205	protein histidine kinase activity
TD68_RS13560	COG0745	RESPONSE REGULATOR receiver
TD68_RS13570	COG1191	sigma factor activity
TD68_RS13575	COG2140	Oxalate decarboxylase
TD68_RS13585	COG0577	efflux transmembrane transporter activity
TD68_RS13590	COG1136	(ABC) transporter
TD68_RS13595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TD68_RS13600	COG1120	ATPase activity
TD68_RS13605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS13610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS13615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_RS13620	COG0531	amino acid
TD68_RS13635	COG1988	membrane-bound metal-dependent
TD68_RS13640	COG1368	sulfuric ester hydrolase activity
TD68_RS13645	COG1910	domain protein
TD68_RS13650	COG0725	ABC transporter, periplasmic molybdate-binding protein
TD68_RS13655	COG4149	molybdate abc transporter
TD68_RS13665	COG0656	L-ascorbic acid biosynthetic process
TD68_RS13690	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TD68_RS13695	COG3973	AAA domain
TD68_RS13700	COG2860	membrane
TD68_RS13710	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TD68_RS13715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TD68_RS13720	COG2217	Heavy metal translocating P-type atpase
TD68_RS13725	COG2217	Heavy metal translocating P-type atpase
TD68_RS13730	COG2608	mercury ion transmembrane transporter activity
TD68_RS13735	COG1937	Protein conserved in bacteria
TD68_RS13740	COG0673	inositol 2-dehydrogenase activity
TD68_RS13745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TD68_RS13750	COG1289	transmembrane transporter activity
TD68_RS13755	COG1846	Transcriptional regulator
TD68_RS13765	COG2076	Multidrug Resistance protein
TD68_RS13770	COG1309	transcriptional regulator
TD68_RS13775	COG1216	Glycosyl transferase, family 2
TD68_RS13775	COG1442	glycosyl transferase family 8
TD68_RS13780	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TD68_RS13785	COG0557	exoribonuclease II activity
TD68_RS13790	COG1647	Serine aminopeptidase, S33
TD68_RS13795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TD68_RS13800	COG1476	TRANSCRIPTIONal
TD68_RS13805	COG1396	sequence-specific DNA binding
TD68_RS13810	COG1396	sequence-specific DNA binding
TD68_RS13815	COG1733	regulation of RNA biosynthetic process
TD68_RS13820	COG0840	transmembrane signaling receptor activity
TD68_RS13825	COG1174	glycine betaine transport
TD68_RS13830	COG1732	Glycine betaine
TD68_RS13835	COG1174	glycine betaine transport
TD68_RS13840	COG1125	glycine betaine transport
TD68_RS13840	COG0517	IMP dehydrogenase activity
TD68_RS13845	COG1510	regulation of RNA biosynthetic process
TD68_RS13850	COG1174	glycine betaine transport
TD68_RS13855	COG1732	Glycine betaine
TD68_RS13860	COG1174	glycine betaine transport
TD68_RS13865	COG0517	IMP dehydrogenase activity
TD68_RS13865	COG1125	glycine betaine transport
TD68_RS13870	COG1510	regulation of RNA biosynthetic process
TD68_RS13875	COG2095	MarC family integral membrane protein
TD68_RS13880	COG3064	Membrane
TD68_RS13885	COG4640	response to antibiotic
TD68_RS13890	COG0456	acetyltransferase
TD68_RS13905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TD68_RS13925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS13930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TD68_RS13940	COG2234	aminopeptidase activity
TD68_RS13950	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TD68_RS13960	COG0126	phosphoglycerate kinase activity
TD68_RS13965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TD68_RS13970	COG2390	Transcriptional regulator
TD68_RS13975	COG2814	Major facilitator Superfamily
TD68_RS13980	COG1609	Transcriptional regulator
TD68_RS13985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_RS13990	COG0583	DNA-binding transcription factor activity
TD68_RS13995	COG0697	spore germination
TD68_RS14000	COG1113	amino acid transport
TD68_RS14005	COG3858	chitin binding
TD68_RS14010	COG1556	Lactate utilization protein
TD68_RS14015	COG1139	Iron-sulfur cluster binding protein
TD68_RS14020	COG0247	lactate metabolic process
TD68_RS14025	COG2186	Transcriptional regulator
TD68_RS14030	COG1620	l-lactate permease
TD68_RS14035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
TD68_RS14045	COG5039	Polysaccharide pyruvyl transferase
TD68_RS14050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TD68_RS14055	COG0110	maltose O-acetyltransferase activity
TD68_RS14060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TD68_RS14065	COG2244	polysaccharide biosynthetic process
TD68_RS14070	COG1216	Glycosyl transferase, family 2
TD68_RS14075	COG5039	Polysaccharide pyruvyl transferase
TD68_RS14080	COG1216	Glycosyl transferase, family 2
TD68_RS14090	COG0438	transferase activity, transferring glycosyl groups
TD68_RS14095	COG1215	transferase activity, transferring glycosyl groups
TD68_RS14100	COG0438	transferase activity, transferring glycosyl groups
TD68_RS14105	COG1086	Polysaccharide biosynthesis protein
TD68_RS14110	COG0489	protein tyrosine kinase activity
TD68_RS14115	COG3944	biosynthesis protein
TD68_RS14120	COG1396	sequence-specific DNA binding
TD68_RS14140	COG1131	(ABC) transporter
TD68_RS14160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TD68_RS14165	COG0583	DNA-binding transcription factor activity
TD68_RS14170	COG1621	beta-fructofuranosidase activity
TD68_RS14175	COG1621	beta-fructofuranosidase activity
TD68_RS14180	COG0531	amino acid
TD68_RS14185	COG1309	transcriptional regulator
TD68_RS14190	COG2076	Multidrug Resistance protein
TD68_RS14195	COG2076	Multidrug Resistance protein
TD68_RS14200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS14225	COG1611	Belongs to the LOG family
TD68_RS14230	COG1694	Mazg nucleotide pyrophosphohydrolase
TD68_RS14235	COG0659	secondary active sulfate transmembrane transporter activity
TD68_RS14240	COG0288	reversible hydration of carbon dioxide
TD68_RS14245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TD68_RS14250	COG0577	efflux transmembrane transporter activity
TD68_RS14255	COG1136	(ABC) transporter
TD68_RS14260	COG5002	protein histidine kinase activity
TD68_RS14265	COG0745	RESPONSE REGULATOR receiver
TD68_RS14270	COG4290	ribonuclease
TD68_RS14275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
TD68_RS14280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS14290	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TD68_RS14295	COG1660	Displays ATPase and GTPase activities
TD68_RS14300	COG1051	belongs to the nudix hydrolase family
TD68_RS14305	COG0492	ferredoxin-NADP+ reductase activity
TD68_RS14310	COG0791	NLP P60 protein
TD68_RS14310	COG3883	PFAM NLP P60 protein
TD68_RS14315	COG0457	Tetratricopeptide repeat
TD68_RS14320	COG1132	(ABC) transporter
TD68_RS14330	COG1247	-acetyltransferase
TD68_RS14335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TD68_RS14335	COG0140	phosphoribosyl-ATP diphosphatase activity
TD68_RS14340	COG0107	imidazoleglycerol-phosphate synthase activity
TD68_RS14345	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TD68_RS14355	COG0131	Imidazoleglycerol-phosphate dehydratase
TD68_RS14360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TD68_RS14365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TD68_RS14370	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TD68_RS14375	COG4990	cell redox homeostasis
TD68_RS14380	COG5297	Belongs to the glycosyl hydrolase family 6
TD68_RS14385	COG0110	maltose O-acetyltransferase activity
TD68_RS14390	COG0546	phosphoglycolate phosphatase activity
TD68_RS14395	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TD68_RS14400	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TD68_RS14405	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TD68_RS14410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TD68_RS14420	COG2188	Transcriptional regulator
TD68_RS14425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TD68_RS14430	COG1950	PFAM Membrane protein of
TD68_RS14435	COG1983	PspC domain protein
TD68_RS14440	COG3595	metallopeptidase activity
TD68_RS14455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TD68_RS14465	COG4897	Protein conserved in bacteria
TD68_RS14470	COG0574	Belongs to the PEP-utilizing enzyme family
TD68_RS14470	COG3848	Pyruvate phosphate dikinase
TD68_RS14475	COG1309	transcriptional regulator
TD68_RS14480	COG2814	Major facilitator Superfamily
TD68_RS14495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_RS14505	COG0793	Belongs to the peptidase S41A family
TD68_RS14505	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS14510	COG2177	Part of the ABC transporter FtsEX involved in
TD68_RS14515	COG2884	Cell division ATP-binding protein ftsE
TD68_RS14520	COG2010	Cytochrome c
TD68_RS14525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS14530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TD68_RS14535	COG0653	protein targeting
TD68_RS14540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TD68_RS14555	COG1516	flagellar protein fliS
TD68_RS14560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
TD68_RS14565	COG1334	flagellar protein FlaG
TD68_RS14570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TD68_RS14575	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TD68_RS14580	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TD68_RS14590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TD68_RS14595	COG1256	bacterial-type flagellum assembly
TD68_RS14595	COG4786	Flagellar basal body rod
TD68_RS14600	COG3418	PFAM FlgN family protein
TD68_RS14605	COG2747	anti-sigma28 factor FlgM
TD68_RS14615	COG1040	competence protein
TD68_RS14625	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
TD68_RS14630	COG1307	EDD domain protein, DegV family
TD68_RS14635	COG2197	response regulator
TD68_RS14640	COG4585	Histidine kinase
TD68_RS14645	COG1739	Uncharacterized protein family UPF0029
TD68_RS14650	COG1316	TRANSCRIPTIONal
TD68_RS14655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TD68_RS14660	COG0438	transferase activity, transferring glycosyl groups
TD68_RS14665	COG1215	transferase activity, transferring glycosyl groups
TD68_RS14670	COG3206	protein involved in exopolysaccharide biosynthesis
TD68_RS14675	COG3307	-O-antigen
TD68_RS14680	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD68_RS14685	COG0438	transferase activity, transferring glycosyl groups
TD68_RS14685	COG0297	glycogen (starch) synthase activity
TD68_RS14690	COG2244	polysaccharide biosynthetic process
TD68_RS14705	COG2247	cell wall binding repeat
TD68_RS14705	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_RS14710	COG2247	cell wall binding repeat
TD68_RS14710	COG2385	sporulation resulting in formation of a cellular spore
TD68_RS14720	COG1316	TRANSCRIPTIONal
TD68_RS14725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TD68_RS14730	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TD68_RS14735	COG1134	teichoic acid transport
TD68_RS14740	COG1682	transport, permease protein
TD68_RS14745	COG0463	Glycosyl transferase, family 2
TD68_RS14745	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_RS14750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_RS14755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TD68_RS14760	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
TD68_RS14765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_RS14770	COG4193	domain, Protein
TD68_RS14775	COG1482	cell wall glycoprotein biosynthetic process
TD68_RS14780	COG0697	spore germination
TD68_RS14785	COG0814	amino acid
TD68_RS14800	COG2814	Major facilitator Superfamily
TD68_RS14805	COG1316	TRANSCRIPTIONal
TD68_RS14810	COG0561	phosphatase activity
TD68_RS14815	COG0791	NLP P60 protein
TD68_RS14820	COG2843	Capsule synthesis protein
TD68_RS14830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TD68_RS14835	COG0697	spore germination
TD68_RS14840	COG0531	amino acid
TD68_RS14850	COG1609	Transcriptional regulator
TD68_RS14855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_RS14860	COG1869	D-ribose catabolic process
TD68_RS14865	COG1129	ABC transporter
TD68_RS14870	COG1172	Belongs to the binding-protein-dependent transport system permease family
TD68_RS14875	COG1879	ABC-type sugar transport system periplasmic component
TD68_RS14880	COG3103	Sh3 type 3 domain protein
TD68_RS14890	COG2249	NAD(P)H dehydrogenase (quinone) activity
TD68_RS14895	COG3527	Alpha-acetolactate decarboxylase
TD68_RS14900	COG0028	Belongs to the TPP enzyme family
TD68_RS14905	COG0583	DNA-binding transcription factor activity
TD68_RS14910	COG5337	Spore coat protein CotH
TD68_RS14920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TD68_RS14925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS14940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TD68_RS14950	COG0405	Gamma-glutamyltransferase
TD68_RS14955	COG1522	sequence-specific DNA binding
TD68_RS14960	COG2059	Chromate
TD68_RS14965	COG2059	Chromate
TD68_RS14975	COG0655	NAD(P)H dehydrogenase (quinone) activity
TD68_RS14980	COG0583	DNA-binding transcription factor activity
TD68_RS15005	COG5444	nuclease activity
TD68_RS15025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD68_RS15030	COG4464	protein tyrosine phosphatase activity
TD68_RS15035	COG0489	protein tyrosine kinase activity
TD68_RS15040	COG3944	biosynthesis protein
TD68_RS15045	COG4715	Zinc finger, swim domain protein
TD68_RS15050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TD68_RS15055	COG0561	phosphatase activity
TD68_RS15060	COG1349	DNA-binding transcription factor activity
TD68_RS15065	COG0629	single-stranded DNA binding
TD68_RS15080	COG1970	mechanosensitive ion channel activity
TD68_RS15090	COG0457	Tetratricopeptide repeat
TD68_RS15095	COG4786	Flagellar basal body rod
TD68_RS15100	COG4786	Flagellar basal body rod
TD68_RS15105	COG1077	Cell shape determining protein MreB Mrl
TD68_RS15110	COG1609	Transcriptional regulator
TD68_RS15115	COG1846	Transcriptional regulator
TD68_RS15120	COG2814	Major facilitator Superfamily
TD68_RS15125	COG1953	Uracil, thiamine, allantoin
TD68_RS15130	COG0477	Major facilitator Superfamily
TD68_RS15135	COG1335	isochorismatase
TD68_RS15145	COG0004	ammonium transporteR
TD68_RS15150	COG0347	Belongs to the P(II) protein family
TD68_RS15155	COG0772	Belongs to the SEDS family
TD68_RS15160	COG0671	phosphoesterase, PA-phosphatase related
TD68_RS15170	COG0739	heme binding
TD68_RS15175	COG1247	-acetyltransferase
TD68_RS15185	COG1086	Polysaccharide biosynthesis protein
TD68_RS15190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TD68_RS15195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TD68_RS15200	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
TD68_RS15215	COG2089	acid synthase
TD68_RS15225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD68_RS15230	COG0789	Transcriptional regulator
TD68_RS15240	COG2910	NAD(P)H-binding
TD68_RS15250	COG0804	urea catabolic process
TD68_RS15260	COG0831	urea catabolic process
TD68_RS15265	COG3237	CsbD-like
TD68_RS15270	COG1994	Peptidase M50
TD68_RS15275	COG0457	Tetratricopeptide repeat
TD68_RS15285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TD68_RS15290	COG2304	oxidoreductase activity
TD68_RS15295	COG2304	oxidoreductase activity
TD68_RS15300	COG2385	sporulation resulting in formation of a cellular spore
TD68_RS15305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TD68_RS15315	COG4836	Membrane
TD68_RS15325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TD68_RS15330	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TD68_RS15335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TD68_RS15345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TD68_RS15350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TD68_RS15370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TD68_RS15375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TD68_RS15380	COG4475	Protein of unknown function (DUF436)
TD68_RS15385	COG0698	ribose 5-phosphate isomerase
TD68_RS15390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD68_RS15395	COG1971	Probably functions as a manganese efflux pump
TD68_RS15400	COG0009	L-threonylcarbamoyladenylate synthase
TD68_RS15405	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TD68_RS15425	COG2890	protein-(glutamine-N5) methyltransferase activity
TD68_RS15430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TD68_RS15435	COG0346	lactoylglutathione lyase activity
TD68_RS15440	COG0789	Transcriptional regulator
TD68_RS15445	COG0679	Auxin Efflux Carrier
TD68_RS15450	COG0281	malic enzyme
TD68_RS15460	COG0254	rRNA binding
TD68_RS15465	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TD68_RS15470	COG1494	fructose-1,6-bisphosphatase
TD68_RS15475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TD68_RS15485	COG0191	fructose-bisphosphate aldolase activity
TD68_RS15490	COG2204	response regulator
TD68_RS15495	COG4821	SIS domain
TD68_RS15500	COG0504	CTP synthase activity
TD68_RS15505	COG3343	RNA polymerase activity
TD68_RS15510	COG1960	acyl-CoA dehydrogenase activity
TD68_RS15515	COG2181	nitrate reductase activity
TD68_RS15515	COG0247	lactate metabolic process
TD68_RS15520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD68_RS15525	COG4294	response to UV
TD68_RS15535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TD68_RS15540	COG1132	(ABC) transporter
TD68_RS15545	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TD68_RS15550	COG2181	nitrate reductase activity
TD68_RS15555	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
TD68_RS15560	COG1140	nitrate reductase beta subunit
TD68_RS15565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
TD68_RS15570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TD68_RS15580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TD68_RS15585	COG2223	nitrite transmembrane transporter activity
TD68_RS15590	COG0018	arginyl-trna synthetase
TD68_RS15595	COG4506	Protein conserved in bacteria
TD68_RS15605	COG0535	radical SAM domain protein
TD68_RS15615	COG1131	(ABC) transporter
TD68_RS15640	COG3391	amine dehydrogenase activity
TD68_RS15645	COG3391	amine dehydrogenase activity
TD68_RS15650	COG1388	LysM domain
TD68_RS15655	COG0457	Tetratricopeptide repeat
TD68_RS15665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TD68_RS15670	COG0010	Belongs to the arginase family
TD68_RS15675	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TD68_RS15680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TD68_RS15690	COG1994	Peptidase M50
TD68_RS15695	COG1942	4-Oxalocrotonate Tautomerase
TD68_RS15700	COG1846	Transcriptional regulator
TD68_RS15705	COG0531	amino acid
TD68_RS15710	COG3465	dGTPase activity
TD68_RS15715	COG1078	dGTPase activity
TD68_RS15720	COG4844	belongs to the
TD68_RS15730	COG0697	spore germination
TD68_RS15735	COG0095	Lipoate-protein ligase
TD68_RS15740	COG0583	DNA-binding transcription factor activity
TD68_RS15750	COG0280	phosphate acetyltransferase
TD68_RS15755	COG3253	May function as heme-dependent peroxidase
TD68_RS15760	COG2814	Major facilitator Superfamily
TD68_RS15765	COG2814	Major facilitator Superfamily
TD68_RS15775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
TD68_RS15780	COG1091	dTDP-4-dehydrorhamnose reductase activity
TD68_RS15785	COG1088	dTDP-glucose 4,6-dehydratase activity
TD68_RS15790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TD68_RS15795	COG0456	acetyltransferase
TD68_RS15800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_RS15805	COG0463	Glycosyl transferase, family 2
TD68_RS15815	COG2363	Small membrane protein
TD68_RS15820	COG2233	PERMEase
TD68_RS15830	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS15835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TD68_RS15840	COG1216	Glycosyl transferase, family 2
TD68_RS15850	COG1695	Transcriptional regulator
TD68_RS15855	COG0351	phosphomethylpyrimidine kinase
TD68_RS15865	COG0110	maltose O-acetyltransferase activity
TD68_RS15870	COG1621	beta-fructofuranosidase activity
TD68_RS15875	COG1263	PTS System
TD68_RS15875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS15880	COG2116	formate transmembrane transporter activity
TD68_RS15885	COG3711	transcriptional antiterminator
TD68_RS15895	COG1404	Belongs to the peptidase S8 family
TD68_RS15905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_RS15910	COG0778	Nitroreductase
TD68_RS15915	COG0772	Belongs to the SEDS family
TD68_RS15930	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
TD68_RS15940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TD68_RS15945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TD68_RS15950	COG2261	transglycosylase associated protein
TD68_RS15955	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
TD68_RS15960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TD68_RS15965	COG2246	polysaccharide biosynthetic process
TD68_RS15970	COG1309	transcriptional regulator
TD68_RS15990	COG3162	membrane
TD68_RS15995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_RS16000	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TD68_RS16005	COG0352	thiamine-phosphate diphosphorylase activity
TD68_RS16010	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TD68_RS16015	COG0583	DNA-binding transcription factor activity
TD68_RS16025	COG1346	cytolysis
TD68_RS16030	COG1131	(ABC) transporter
TD68_RS16050	COG1346	cytolysis
TD68_RS16055	COG4895	conserved protein (DUF2196)
TD68_RS16060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TD68_RS16065	COG0346	lactoylglutathione lyase activity
TD68_RS16070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_RS16080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS16080	COG1263	PTS System
TD68_RS16085	COG3711	transcriptional antiterminator
TD68_RS16090	COG1442	glycosyl transferase family 8
TD68_RS16095	COG5522	Integral membrane protein (intg_mem_TP0381)
TD68_RS16100	COG2234	aminopeptidase activity
TD68_RS16105	COG0457	Tetratricopeptide repeat
TD68_RS16110	COG1846	Transcriptional regulator
TD68_RS16115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TD68_RS16120	COG2357	RelA SpoT domain protein
TD68_RS16125	COG1575	Belongs to the MenA family. Type 1 subfamily
TD68_RS16130	COG0569	domain protein
TD68_RS16140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS16145	COG1696	Membrane protein involved in D-alanine export
TD68_RS16155	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
TD68_RS16160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_RS16165	COG1486	melibiose metabolic process
TD68_RS16170	COG1447	Phosphotransferase system cellobiose-specific component IIA
TD68_RS16175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_RS16180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TD68_RS16185	COG3711	transcriptional antiterminator
TD68_RS16185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS16190	COG2094	Belongs to the DNA glycosylase MPG family
TD68_RS16200	COG0753	catalase activity
TD68_RS16210	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD68_RS16215	COG1131	(ABC) transporter
TD68_RS16235	COG1595	DNA-templated transcription, initiation
TD68_RS16240	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TD68_RS16245	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TD68_RS16250	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
TD68_RS16255	COG4988	ABC transporter
TD68_RS16260	COG1294	oxidase, subunit
TD68_RS16265	COG1271	oxidase subunit
TD68_RS16270	COG3493	citrate carrier protein
TD68_RS16280	COG0726	polysaccharide deacetylase
TD68_RS16285	COG3842	ATPase activity
TD68_RS16290	COG2508	Transcriptional regulator
TD68_RS16300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS16310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TD68_RS16320	COG4585	Histidine kinase
TD68_RS16325	COG2197	response regulator
TD68_RS16330	COG2195	Cleaves the N-terminal amino acid of tripeptides
TD68_RS16340	COG4894	glucomannan catabolic process
TD68_RS16345	COG0457	Tetratricopeptide repeat
TD68_RS16360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TD68_RS16390	COG2002	toxin-antitoxin pair type II binding
TD68_RS16400	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TD68_RS16405	COG3290	protein histidine kinase activity
TD68_RS16405	COG3829	transcription factor binding
TD68_RS16410	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS16415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TD68_RS16420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
TD68_RS16425	COG2610	gluconate transmembrane transporter activity
TD68_RS16430	COG0500	methyltransferase
TD68_RS16435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD68_RS16450	COG0693	protein deglycase activity
TD68_RS16450	COG0753	catalase activity
TD68_RS16455	COG2851	Citrate transporter
TD68_RS16465	COG3711	transcriptional antiterminator
TD68_RS16475	COG2270	Major facilitator Superfamily
TD68_RS16480	COG0513	Belongs to the DEAD box helicase family
TD68_RS16485	COG0346	lactoylglutathione lyase activity
TD68_RS16490	COG1357	PFAM Pentapeptide repeats (8 copies)
TD68_RS16495	COG3401	FG-GAP repeat protein
TD68_RS16495	COG2755	lipolytic protein G-D-S-L family
TD68_RS16525	COG0697	spore germination
TD68_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS16550	COG0589	response to stress
TD68_RS16555	COG2723	6-phospho-beta-galactosidase activity
TD68_RS16560	COG2190	(PTS) system
TD68_RS16560	COG1263	PTS System
TD68_RS16560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS16565	COG3977	Valine--pyruvate aminotransferase
TD68_RS16580	COG1181	Belongs to the D-alanine--D-alanine ligase family
TD68_RS16595	COG0494	nUDIX hydrolase
TD68_RS16600	COG3507	Belongs to the glycosyl hydrolase 43 family
TD68_RS16610	COG2986	histidine ammonia-lyase
TD68_RS16615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
TD68_RS16620	COG1228	amidohydrolase
TD68_RS16625	COG0010	Belongs to the arginase family
TD68_RS16630	COG0833	amino acid
TD68_RS16635	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TD68_RS16640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
TD68_RS16645	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TD68_RS16650	COG2390	Transcriptional regulator
TD68_RS16660	COG3192	ethanolamine utilization protein
TD68_RS16665	COG1940	carbohydrate kinase activity
TD68_RS16670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
TD68_RS16675	COG0561	phosphatase activity
TD68_RS16700	COG5294	Protein conserved in bacteria
TD68_RS16705	COG0577	efflux transmembrane transporter activity
TD68_RS16710	COG1136	(ABC) transporter
TD68_RS16715	COG2205	protein histidine kinase activity
TD68_RS16720	COG0745	RESPONSE REGULATOR receiver
TD68_RS16730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_RS16745	COG1082	Xylose isomerase domain protein TIM barrel
TD68_RS16750	COG0673	inositol 2-dehydrogenase activity
TD68_RS16755	COG2814	Major facilitator Superfamily
TD68_RS16760	COG1082	Xylose isomerase domain protein TIM barrel
TD68_RS16765	COG3962	Belongs to the TPP enzyme family
TD68_RS16770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TD68_RS16785	COG1349	DNA-binding transcription factor activity
TD68_RS16790	COG0667	Aldo Keto reductase
TD68_RS16810	COG2814	Major facilitator Superfamily
TD68_RS16815	COG0326	Molecular chaperone. Has ATPase activity
TD68_RS16820	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS16825	COG1309	transcriptional regulator
TD68_RS16830	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS16840	COG1714	RDD family
TD68_RS16845	COG2311	Membrane
TD68_RS16850	COG1917	Cupin 2, conserved barrel domain protein
TD68_RS16855	COG1309	transcriptional regulator
TD68_RS16870	COG5039	Polysaccharide pyruvyl transferase
TD68_RS16875	COG1929	Belongs to the glycerate kinase type-1 family
TD68_RS16880	COG2610	gluconate transmembrane transporter activity
TD68_RS16885	COG3835	regulator
TD68_RS16890	COG1802	Transcriptional regulator
TD68_RS16895	COG1070	Carbohydrate kinase
TD68_RS16900	COG2610	gluconate transmembrane transporter activity
TD68_RS16905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TD68_RS16915	COG0450	alkyl hydroperoxide reductase
TD68_RS16920	COG3634	alkyl hydroperoxide reductase activity
TD68_RS16930	COG1113	amino acid transport
TD68_RS16940	COG1131	(ABC) transporter
TD68_RS16945	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
TD68_RS17040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TD68_RS17050	COG1063	alcohol dehydrogenase
TD68_RS17065	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
TD68_RS17070	COG0456	acetyltransferase
TD68_RS17075	COG0010	Belongs to the arginase family
TD68_RS17080	COG0833	amino acid
TD68_RS17085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TD68_RS17090	COG5658	integral membrane protein
TD68_RS17095	COG0640	Transcriptional regulator
TD68_RS17100	COG3829	transcription factor binding
TD68_RS17110	COG0488	(ABC) transporter
TD68_RS17125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TD68_RS17130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TD68_RS17135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TD68_RS17140	COG4853	Protein conserved in bacteria
TD68_RS17145	COG4863	YycH protein
TD68_RS17150	COG5002	protein histidine kinase activity
TD68_RS17155	COG0745	RESPONSE REGULATOR receiver
TD68_RS17185	COG0346	lactoylglutathione lyase activity
TD68_RS17190	COG0305	Participates in initiation and elongation during chromosome replication
TD68_RS17205	COG2807	transmembrane transport
TD68_RS17210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TD68_RS17215	COG0359	binds to the 23S rRNA
TD68_RS17220	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
TD68_RS17225	COG4241	membrane
TD68_RS17235	COG5577	PFAM Coat F domain
TD68_RS17240	COG1733	regulation of RNA biosynthetic process
TD68_RS17255	COG2271	Major facilitator Superfamily
TD68_RS17260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS17270	COG0473	3-isopropylmalate dehydrogenase activity
TD68_RS17275	COG1802	Transcriptional regulator
TD68_RS17280	COG0789	Transcriptional regulator
TD68_RS17280	COG4978	Transcriptional regulator
TD68_RS17290	COG0745	RESPONSE REGULATOR receiver
TD68_RS17295	COG2205	protein histidine kinase activity
TD68_RS17305	COG0477	Major facilitator Superfamily
TD68_RS17315	COG0425	Belongs to the sulfur carrier protein TusA family
TD68_RS17315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TD68_RS17330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS17335	COG1331	Highly conserved protein containing a thioredoxin domain
TD68_RS17340	COG2814	Major facilitator Superfamily
TD68_RS17340	COG0477	Major facilitator Superfamily
TD68_RS17345	COG0346	lactoylglutathione lyase activity
TD68_RS17350	COG1609	Transcriptional regulator
TD68_RS17355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TD68_RS17360	COG2169	Transcriptional regulator
TD68_RS17365	COG0708	Exodeoxyribonuclease III
TD68_RS17370	COG0697	spore germination
TD68_RS17375	COG1802	Transcriptional regulator
TD68_RS17390	COG0629	single-stranded DNA binding
TD68_RS17395	COG0360	Binds together with S18 to 16S ribosomal RNA
TD68_RS17400	COG0012	GTP binding
TD68_RS17405	COG0243	molybdopterin cofactor binding
TD68_RS17410	COG4481	Protein conserved in bacteria
TD68_RS17415	COG3949	Membrane
TD68_RS17425	COG1475	DNA binding
TD68_RS17430	COG1192	Involved in chromosome partitioning
TD68_RS17440	COG1475	DNA binding
TD68_RS17445	COG0357	Ribosomal RNA small subunit methyltransferase G
TD68_RS17450	COG0445	tRNA wobble uridine modification
TD68_RS17460	COG1847	R3H domain protein
TD68_RS17465	COG0706	membrane insertase activity
TD68_RS17470	COG0594	ribonuclease P activity
TD68_RS17480	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TD68_RS17485	COG0592	DNA-directed DNA polymerase activity
TD68_RS17490	COG2501	S4 domain
TD68_RS17495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TD68_RS17505	COG0187	DNA topoisomerase II activity
TD68_RS17510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TD68_RS17535	COG0517	IMP dehydrogenase activity
TD68_RS17535	COG0516	GMP reductase activity
TD68_RS17540	COG1686	Belongs to the peptidase S11 family
TD68_RS17565	COG1428	Deoxynucleoside kinase
TD68_RS17570	COG1428	Deoxynucleoside kinase
TD68_RS17575	COG1388	LysM domain
TD68_RS17575	COG3858	chitin binding
TD68_RS17580	COG1335	isochorismatase
TD68_RS17585	COG0590	tRNA wobble adenosine to inosine editing
TD68_RS17590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TD68_RS17595	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TD68_RS17600	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TD68_RS17635	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
TD68_RS17640	COG3853	Toxic anion resistance protein (TelA)
TD68_RS17645	COG1982	Orn Lys Arg decarboxylase major
TD68_RS17650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TD68_RS17655	COG3870	Protein conserved in bacteria
TD68_RS17660	COG1728	Protein conserved in bacteria
TD68_RS17665	COG0470	DNA polymerase III
TD68_RS17670	COG1774	PSP1 C-terminal conserved region
TD68_RS17680	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TD68_RS17685	COG2827	Endonuclease containing a URI domain
TD68_RS17690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TD68_RS17695	COG2002	toxin-antitoxin pair type II binding
TD68_RS17700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_RS17700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TD68_RS17705	COG0084	hydrolase, TatD family'
TD68_RS17710	COG3584	3D domain protein
TD68_RS17710	COG3583	domain protein
TD68_RS17715	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
TD68_RS17720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TD68_RS17730	COG4466	Protein conserved in bacteria
TD68_RS17740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TD68_RS17745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TD68_RS17750	COG0251	oxidation-reduction process
TD68_RS17765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TD68_RS17770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TD68_RS17775	COG0193	aminoacyl-tRNA hydrolase activity
TD68_RS17785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TD68_RS17790	COG2002	toxin-antitoxin pair type II binding
TD68_RS17795	COG2244	polysaccharide biosynthetic process
TD68_RS17800	COG3956	TIGRFAM MazG family protein
TD68_RS17805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TD68_RS17820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
TD68_RS17825	COG1098	S1 RNA binding domain
TD68_RS17840	COG2208	phosphoserine phosphatase activity
TD68_RS17845	COG2304	oxidoreductase activity
TD68_RS17850	COG0515	serine threonine protein kinase
TD68_RS17855	COG0037	tRNA processing
TD68_RS17860	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TD68_RS17865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TD68_RS17880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TD68_RS17885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TD68_RS17890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TD68_RS17895	COG0512	Glutamine amidotransferase of anthranilate synthase
TD68_RS17900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_RS17905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TD68_RS17910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TD68_RS17915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TD68_RS17920	COG1396	sequence-specific DNA binding
TD68_RS17925	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TD68_RS17930	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TD68_RS18015	COG4463	regulation of RNA biosynthetic process
TD68_RS18020	COG3880	PFAM UvrB UvrC protein
TD68_RS18025	COG3869	Catalyzes the specific phosphorylation of arginine residues in
TD68_RS18030	COG0542	response to heat
TD68_RS18035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TD68_RS18040	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
TD68_RS18045	COG4956	integral membrane protein (PIN domain superfamily)
TD68_RS18050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TD68_RS18055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TD68_RS18060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TD68_RS18065	COG1045	serine acetyltransferase
TD68_RS18070	COG0215	cysteine-tRNA ligase activity
TD68_RS18075	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
TD68_RS18080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TD68_RS18085	COG3688	RNA-binding protein containing a PIN domain
TD68_RS18090	COG1595	DNA-templated transcription, initiation
TD68_RS18100	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TD68_RS18105	COG0250	Participates in transcription elongation, termination and antitermination
TD68_RS18120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TD68_RS18130	COG2813	Specifically methylates the guanine in position
TD68_RS18135	COG0085	RNA polymerase activity
TD68_RS18145	COG1358	cellular component organization or biogenesis
TD68_RS18155	COG0049	tRNA binding
TD68_RS18160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TD68_RS18170	COG0596	Alpha beta hydrolase
TD68_RS18180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TD68_RS18195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TD68_RS18225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TD68_RS18250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TD68_RS18260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TD68_RS18265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TD68_RS18275	COG0200	Binds to the 23S rRNA
TD68_RS18280	COG0201	protein transport
TD68_RS18290	COG0024	Methionine aminopeptidase
TD68_RS18295	COG2163	COG2163 Ribosomal protein L14E L6E L27E
TD68_RS18305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TD68_RS18315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TD68_RS18325	COG0203	ribosomal protein L17
TD68_RS18330	COG1122	ATPase activity
TD68_RS18335	COG1122	ATPase activity
TD68_RS18340	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TD68_RS18345	COG0101	tRNA pseudouridine synthase activity
TD68_RS18355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TD68_RS18360	COG2226	methyltransferase
TD68_RS18370	COG0860	N-Acetylmuramoyl-L-alanine amidase
TD68_RS18375	COG0489	protein tyrosine kinase activity
TD68_RS18385	COG2194	sulfuric ester hydrolase activity
TD68_RS18390	COG0726	polysaccharide deacetylase
TD68_RS18420	COG0738	Major facilitator superfamily
TD68_RS18425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TD68_RS18435	COG1063	alcohol dehydrogenase
TD68_RS18440	COG0659	secondary active sulfate transmembrane transporter activity
TD68_RS18445	COG0385	Bile acid
TD68_RS18450	COG2819	hydrolase of the alpha beta superfamily
TD68_RS18455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS18460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS18465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_RS18470	COG2207	Transcriptional regulator
TD68_RS18470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TD68_RS18475	COG3876	Protein conserved in bacteria
TD68_RS18480	COG1472	Belongs to the glycosyl hydrolase 3 family
TD68_RS18485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
TD68_RS18490	COG1263	PTS System
TD68_RS18490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS18495	COG1737	Transcriptional regulator
TD68_RS18500	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TD68_RS18505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS18510	COG1683	Conserved Protein
TD68_RS18540	COG1595	DNA-templated transcription, initiation
TD68_RS18545	COG5662	AntiSigma factor
TD68_RS18550	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TD68_RS18555	COG4856	YbbR-like protein
TD68_RS18560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TD68_RS18570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TD68_RS18575	COG3002	Belongs to the UPF0753 family
TD68_RS18580	COG0288	reversible hydration of carbon dioxide
TD68_RS18590	COG5609	conserved protein (DUF2294)
TD68_RS18595	COG0640	Transcriptional regulator
TD68_RS18600	COG2814	Major facilitator Superfamily
TD68_RS18605	COG1413	lyase activity
TD68_RS18630	COG0076	glutamate decarboxylase activity
TD68_RS18640	COG1346	cytolysis
TD68_RS18645	COG1380	Effector of murein hydrolase LrgA
TD68_RS18650	COG1846	Transcriptional regulator
TD68_RS18655	COG1113	amino acid transport
TD68_RS18670	COG2602	Beta-lactamase
TD68_RS18675	COG2124	cytochrome p450
TD68_RS18685	COG0531	amino acid
TD68_RS18690	COG0584	glycerophosphoryl diester phosphodiesterase
TD68_RS18695	COG2271	Major facilitator Superfamily
TD68_RS18710	COG1134	teichoic acid transport
TD68_RS18720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TD68_RS18735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TD68_RS18755	COG3409	Peptidoglycan-binding domain 1 protein
TD68_RS18760	COG0697	spore germination
TD68_RS18765	COG0371	Dehydrogenase
TD68_RS18770	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
TD68_RS18780	COG0596	Alpha beta hydrolase
TD68_RS18785	COG1183	phosphatidylcholine synthase activity
TD68_RS18790	COG0586	Pfam SNARE associated Golgi protein
TD68_RS18795	COG0688	phosphatidylethanolamine metabolic process
TD68_RS18800	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TD68_RS18810	COG1404	Belongs to the peptidase S8 family
TD68_RS18815	COG2312	Erythromycin esterase
TD68_RS18820	COG2207	Transcriptional regulator
TD68_RS18825	COG1054	Belongs to the UPF0176 family
TD68_RS18830	COG1301	dicarboxylic acid transport
TD68_RS18835	COG2190	(PTS) system
TD68_RS18835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS18835	COG1263	PTS System
TD68_RS18835	COG1263	PTS System
TD68_RS18835	COG2190	(PTS) system
TD68_RS18835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TD68_RS18840	COG0363	glucosamine-6-phosphate deaminase activity
TD68_RS18845	COG2188	Transcriptional regulator
TD68_RS18855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TD68_RS18860	COG0833	amino acid
TD68_RS18865	COG2040	homocysteine
TD68_RS18870	COG1115	amino acid carrier protein
TD68_RS18875	COG2066	Belongs to the glutaminase family
TD68_RS18880	COG4191	Histidine kinase
TD68_RS18885	COG0784	Response regulator, receiver
TD68_RS18890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TD68_RS18895	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS18900	COG2271	Major facilitator Superfamily
TD68_RS18905	COG4948	Mandelate Racemase Muconate Lactonizing
TD68_RS18910	COG2186	Transcriptional regulator
TD68_RS18915	COG2721	sulfolactate sulfo-lyase activity
TD68_RS18920	COG3173	Aminoglycoside phosphotransferase
TD68_RS18935	COG0745	RESPONSE REGULATOR receiver
TD68_RS18940	COG2205	protein histidine kinase activity
TD68_RS18945	COG1131	(ABC) transporter
TD68_RS18970	COG3773	Cell wall hydrolase
TD68_RS18975	COG3540	Alkaline phosphatase
TD68_RS18980	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TD68_RS18985	COG0805	protein transport
TD68_RS18995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TD68_RS19000	COG0477	Major facilitator Superfamily
TD68_RS19005	COG1309	transcriptional regulator
TD68_RS19010	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
TD68_RS19015	COG3012	SEC-C Motif Domain Protein
TD68_RS19015	COG1405	negative regulation of cell septum assembly
TD68_RS19020	COG0667	Aldo Keto reductase
TD68_RS19030	COG1595	DNA-templated transcription, initiation
TD68_RS19035	COG0735	belongs to the Fur family
TD68_RS19040	COG1595	DNA-templated transcription, initiation
TD68_RS19045	COG1876	peptidase activity
TD68_RS19050	COG0457	Tetratricopeptide repeat
TD68_RS19055	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS19060	COG0366	Alpha amylase catalytic
TD68_RS19065	COG0803	Belongs to the bacterial solute-binding protein 9 family
TD68_RS19070	COG1121	(ABC) transporter
TD68_RS19075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TD68_RS19080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_RS19085	COG2310	stress, protein
TD68_RS19090	COG2310	stress, protein
TD68_RS19095	COG2310	stress, protein
TD68_RS19100	COG0861	Integral membrane protein TerC family
TD68_RS19130	COG3853	Toxic anion resistance protein (TelA)
TD68_RS19135	COG0477	Major facilitator Superfamily
TD68_RS19140	COG4175	Glycine betaine
TD68_RS19140	COG0517	IMP dehydrogenase activity
TD68_RS19145	COG4176	ABC-type proline glycine betaine transport system permease component
TD68_RS19150	COG2113	Glycine betaine
TD68_RS19155	COG1473	amidohydrolase
TD68_RS19160	COG1288	antiporter activity
TD68_RS19170	COG0039	L-malate dehydrogenase activity
TD68_RS19175	COG1620	l-lactate permease
TD68_RS19180	COG2814	Major facilitator Superfamily
TD68_RS19185	COG1846	Transcriptional regulator
TD68_RS19190	COG1280	lysine exporter protein (LysE YggA)
TD68_RS19195	COG3403	YqcI/YcgG family
TD68_RS19200	COG1113	amino acid transport
TD68_RS19205	COG3665	Urea carboxylase-associated protein
TD68_RS19215	COG1660	Displays ATPase and GTPase activities
TD68_RS19220	COG1082	Xylose isomerase domain protein TIM barrel
TD68_RS19225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TD68_RS19235	COG3458	cephalosporin-C deacetylase activity
TD68_RS19240	COG3541	Predicted nucleotidyltransferase
TD68_RS19245	COG0506	proline dehydrogenase activity
TD68_RS19250	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS19255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_RS19260	COG2508	Transcriptional regulator
TD68_RS19280	COG3689	TIGRFAM TIGR03943 family protein
TD68_RS19285	COG0701	Predicted permease
TD68_RS19290	COG2267	carboxylic ester hydrolase activity
TD68_RS19295	COG0492	ferredoxin-NADP+ reductase activity
TD68_RS19300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TD68_RS19300	COG1587	Uroporphyrinogen-III synthase
TD68_RS19305	COG2146	nitrite reductase [NAD(P)H] activity
TD68_RS19310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TD68_RS19315	COG0243	molybdopterin cofactor binding
TD68_RS19320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TD68_RS19325	COG2223	nitrite transmembrane transporter activity
TD68_RS19330	COG1469	GTP cyclohydrolase I activity
TD68_RS19335	COG1376	ErfK ybiS ycfS ynhG family protein
TD68_RS19340	COG0523	cobalamin synthesis protein
TD68_RS19345	COG0765	amino acid transport
TD68_RS19350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_RS19355	COG1063	alcohol dehydrogenase
TD68_RS19360	COG1714	RDD family
TD68_RS19385	COG2723	6-phospho-beta-galactosidase activity
TD68_RS19395	COG3209	COG3209 Rhs family protein
TD68_RS19400	COG0840	transmembrane signaling receptor activity
TD68_RS19400	COG3290	protein histidine kinase activity
TD68_RS19405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TD68_RS19410	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
TD68_RS19415	COG1733	regulation of RNA biosynthetic process
TD68_RS19420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS19430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TD68_RS19435	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
TD68_RS19445	COG0697	spore germination
TD68_RS19450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS19460	COG2364	Membrane
TD68_RS19465	COG1126	abc transporter atp-binding protein
TD68_RS19470	COG0765	amino acid transport
TD68_RS19475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_RS19480	COG0583	DNA-binding transcription factor activity
TD68_RS19485	COG0163	prenyltransferase activity
TD68_RS19490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TD68_RS19505	COG0596	Alpha beta hydrolase
TD68_RS19510	COG3104	oligopeptide transport
TD68_RS19515	COG5434	Belongs to the glycosyl hydrolase 28 family
TD68_RS19525	COG0697	spore germination
TD68_RS19535	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
TD68_RS19540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TD68_RS19545	COG0456	acetyltransferase
TD68_RS19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TD68_RS19555	COG0765	amino acid transport
TD68_RS19560	COG1126	abc transporter atp-binding protein
TD68_RS19565	COG1473	amidohydrolase
TD68_RS19570	COG2079	MmgE PrpD family protein
TD68_RS19575	COG0457	Tetratricopeptide repeat
TD68_RS19585	COG0527	aspartate kinase activity
TD68_RS19590	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TD68_RS19595	COG4605	iron ion homeostasis
TD68_RS19600	COG4604	ABC transporter, ATP-binding protein
TD68_RS19605	COG4607	ABC-type enterochelin transport system periplasmic component
TD68_RS19610	COG2814	Major facilitator Superfamily
TD68_RS19615	COG1309	transcriptional regulator
TD68_RS19620	COG0457	Tetratricopeptide repeat
TD68_RS19625	COG0778	Nitroreductase
TD68_RS19630	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
TD68_RS19635	COG0640	Transcriptional regulator
TD68_RS19640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS19645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TD68_RS19650	COG1012	belongs to the aldehyde dehydrogenase family
TD68_RS19655	COG4975	Glucose uptake
TD68_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS19665	COG4549	nuclear export factor GLE1
TD68_RS19670	COG1276	copper resistance
TD68_RS19670	COG2372	response to copper ion
TD68_RS19675	COG1349	DNA-binding transcription factor activity
TD68_RS19685	COG2213	PTS system mannitol-specific
TD68_RS19690	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS19695	COG0246	Mannitol dehydrogenase
TD68_RS19700	COG0412	Dienelactone hydrolase
TD68_RS19705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TD68_RS19715	COG0561	phosphatase activity
TD68_RS19720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TD68_RS19725	COG1914	H( )-stimulated, divalent metal cation uptake system
TD68_RS19730	COG4336	lyase activity
TD68_RS19735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TD68_RS19740	COG1984	allophanate hydrolase subunit 2
TD68_RS19745	COG1414	Transcriptional regulator
TD68_RS19750	COG2755	lipolytic protein G-D-S-L family
TD68_RS19760	COG2329	Antibiotic biosynthesis monooxygenase
TD68_RS19765	COG0768	penicillin binding
TD68_RS19770	COG4989	oxidoreductase activity
TD68_RS19775	COG3711	transcriptional antiterminator
TD68_RS19780	COG0318	PFAM AMP-dependent synthetase and ligase
TD68_RS19785	COG2226	methyltransferase
TD68_RS19790	COG1028	Short-chain dehydrogenase reductase Sdr
TD68_RS19795	COG1917	Cupin 2, conserved barrel domain protein
TD68_RS19800	COG3871	stress protein (general stress protein 26)
TD68_RS19815	COG2814	Major facilitator Superfamily
TD68_RS19830	COG1522	sequence-specific DNA binding
TD68_RS19835	COG0551	DNA topoisomerase type I activity
TD68_RS19835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TD68_RS19840	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
TD68_RS19845	COG3706	GGDEF domain
TD68_RS19850	COG5298	Protein conserved in bacteria
TD68_RS19855	COG1215	transferase activity, transferring glycosyl groups
TD68_RS19865	COG0531	amino acid
TD68_RS19870	COG0494	nUDIX hydrolase
TD68_RS19875	COG0028	Belongs to the TPP enzyme family
TD68_RS19885	COG1914	H( )-stimulated, divalent metal cation uptake system
TD68_RS19890	COG2261	transglycosylase associated protein
TD68_RS19895	COG4876	unkown
TD68_RS19900	COG2217	Heavy metal translocating P-type atpase
TD68_RS19905	COG3729	General stress protein
TD68_RS19910	COG0662	Cupin 2, conserved barrel domain protein
TD68_RS19915	COG2329	Antibiotic biosynthesis monooxygenase
TD68_RS19920	COG3546	catalase activity
TD68_RS19925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TD68_RS19930	COG3290	protein histidine kinase activity
TD68_RS19935	COG4565	transcriptional regulatory protein
TD68_RS19940	COG1301	dicarboxylic acid transport
TD68_RS19945	COG0628	permease
TD68_RS19950	COG1131	(ABC) transporter
TD68_RS19955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TD68_RS19965	COG1960	acyl-CoA dehydrogenase activity
TD68_RS19975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TD68_RS19980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TD68_RS19985	COG1181	Belongs to the D-alanine--D-alanine ligase family
TD68_RS19990	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TD68_RS20000	COG0513	Belongs to the DEAD box helicase family
TD68_RS20005	COG3402	PFAM membrane-flanked domain
TD68_RS20010	COG3428	Bacterial PH domain
TD68_RS20015	COG0705	Rhomboid family
TD68_RS20020	COG0736	holo-[acyl-carrier-protein] synthase activity
TD68_RS20025	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TD68_RS20030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TD68_RS20035	COG0864	Transcriptional regulator
TD68_RS20040	COG2337	Toxic component of a toxin-antitoxin (TA) module
TD68_RS20045	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS20050	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS20055	COG2172	sigma factor antagonist activity
TD68_RS20060	COG2208	phosphoserine phosphatase activity
TD68_RS20065	COG1366	Belongs to the anti-sigma-factor antagonist family
TD68_RS20070	COG2172	sigma factor antagonist activity
TD68_RS20075	COG1191	sigma factor activity
TD68_RS20080	COG2208	phosphoserine phosphatase activity
TD68_RS20085	COG2183	response to ionizing radiation
TD68_RS20090	COG3091	SprT-like family
TD68_RS20130	COG0582	viral genome integration into host DNA
TD68_RS20135	COG2856	Zn peptidase
TD68_RS20140	COG1396	sequence-specific DNA binding
TD68_RS20170	COG1674	ftsk spoiiie
TD68_RS20175	COG2946	Replication initiation factor
TD68_RS20220	COG0433	COG0433 Predicted ATPase
TD68_RS20230	COG5644	endopeptidase inhibitor activity
TD68_RS20240	COG0791	NLP P60 protein
TD68_RS20240	COG0741	lytic transglycosylase activity
TD68_RS20260	COG0457	Tetratricopeptide repeat
TD68_RS20270	COG3239	Fatty acid desaturase
TD68_RS20275	COG1278	Cold shock
TD68_RS20280	COG1329	Transcriptional regulator
TD68_RS20285	COG1802	Transcriptional regulator
TD68_RS20290	COG0697	spore germination
TD68_RS20300	COG5444	nuclease activity
TD68_RS20305	COG2364	Membrane
TD68_RS20310	COG1846	Transcriptional regulator
TD68_RS20315	COG0456	acetyltransferase
TD68_RS20320	COG2808	Putative FMN-binding domain
TD68_RS20325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS20335	COG2814	Major facilitator Superfamily
TD68_RS20340	COG0697	spore germination
TD68_RS20345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS20350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TD68_RS20360	COG0640	Transcriptional regulator
TD68_RS20365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TD68_RS20370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TD68_RS20380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TD68_RS20390	COG1846	Transcriptional regulator
TD68_RS20395	COG2409	Drug exporters of the RND superfamily
TD68_RS20395	COG1033	growth of symbiont in host cell
TD68_RS20400	COG3711	transcriptional antiterminator
TD68_RS20400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS20405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_RS20405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TD68_RS20405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TD68_RS20410	COG1482	cell wall glycoprotein biosynthetic process
TD68_RS20415	COG0697	spore germination
TD68_RS20420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TD68_RS20425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TD68_RS20430	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TD68_RS20435	COG1522	sequence-specific DNA binding
TD68_RS20445	COG0488	(ABC) transporter
TD68_RS20450	COG0596	Alpha beta hydrolase
TD68_RS20465	COG2602	Beta-lactamase
TD68_RS20475	COG2814	Major facilitator Superfamily
TD68_RS20485	COG3858	chitin binding
TD68_RS20485	COG1388	LysM domain
TD68_RS20490	COG1819	glycosyl
TD68_RS20515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TD68_RS20525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TD68_RS20530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD68_RS20535	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TD68_RS20540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family