locus-tag	class	description
NXY85_RS00015	COG1785	Belongs to the alkaline phosphatase family
NXY85_RS00020	COG0791	NLP P60 protein
NXY85_RS00020	COG1388	LysM domain
NXY85_RS00025	COG0583	DNA-binding transcription factor activity
NXY85_RS00030	COG0372	Belongs to the citrate synthase family
NXY85_RS00035	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS00040	COG0531	amino acid
NXY85_RS00045	COG0733	neurotransmitter:sodium symporter activity
NXY85_RS00055	COG0456	acetyltransferase
NXY85_RS00060	COG0833	amino acid
NXY85_RS00065	COG4187	Peptidase family M20/M25/M40
NXY85_RS00070	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS00075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXY85_RS00090	COG1595	DNA-templated transcription, initiation
NXY85_RS00095	COG0667	Aldo Keto reductase
NXY85_RS00100	COG0204	Acyl-transferase
NXY85_RS00105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXY85_RS00110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY85_RS00115	COG1253	flavin adenine dinucleotide binding
NXY85_RS00120	COG0789	Transcriptional regulator
NXY85_RS00125	COG1253	flavin adenine dinucleotide binding
NXY85_RS00130	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXY85_RS00135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXY85_RS00140	COG0584	glycerophosphoryl diester phosphodiesterase
NXY85_RS00150	COG0668	transmembrane transport
NXY85_RS00155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXY85_RS00160	COG0726	polysaccharide deacetylase
NXY85_RS00165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXY85_RS00170	COG1757	Na H antiporter
NXY85_RS00175	COG0589	response to stress
NXY85_RS00180	COG1132	(ABC) transporter
NXY85_RS00185	COG1132	(ABC) transporter
NXY85_RS00190	COG0702	epimerase
NXY85_RS00210	COG0189	ligase activity
NXY85_RS00215	COG0189	ligase activity
NXY85_RS00220	COG4399	Belongs to the UPF0754 family
NXY85_RS00230	COG4335	DNA alkylation repair
NXY85_RS00235	COG0561	phosphatase activity
NXY85_RS00240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXY85_RS00250	COG0475	glutathione-regulated potassium exporter activity
NXY85_RS00255	COG0490	domain, Protein
NXY85_RS00265	COG1024	Enoyl-CoA hydratase
NXY85_RS00275	COG4152	abc transporter atp-binding protein
NXY85_RS00280	COG1668	transmembrane transport
NXY85_RS00285	COG0420	3'-5' exonuclease activity
NXY85_RS00290	COG4717	serine-type aminopeptidase activity
NXY85_RS00295	COG3481	metal-dependent phosphohydrolase, HD sub domain
NXY85_RS00305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXY85_RS00340	COG4980	gas vesicle protein
NXY85_RS00355	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXY85_RS00360	COG0537	adenosine 5'-monophosphoramidase activity
NXY85_RS00365	COG1131	(ABC) transporter
NXY85_RS00370	COG4473	ABC transporter
NXY85_RS00380	COG1473	amidohydrolase
NXY85_RS00385	COG3069	C4-dicarboxylate transmembrane transporter activity
NXY85_RS00390	COG2329	Antibiotic biosynthesis monooxygenase
NXY85_RS00395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXY85_RS00400	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NXY85_RS00405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NXY85_RS00410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NXY85_RS00415	COG1309	transcriptional regulator
NXY85_RS00420	COG1511	domain protein
NXY85_RS00425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXY85_RS00435	COG1363	Peptidase, m42
NXY85_RS00440	COG1301	dicarboxylic acid transport
NXY85_RS00450	COG1234	tRNA 3'-trailer cleavage
NXY85_RS00455	COG0095	Lipoate-protein ligase
NXY85_RS00460	COG0702	epimerase
NXY85_RS00465	COG0318	PFAM AMP-dependent synthetase and ligase
NXY85_RS00475	COG0501	Belongs to the peptidase M48B family
NXY85_RS00480	COG1404	Belongs to the peptidase S8 family
NXY85_RS00485	COG0456	acetyltransferase
NXY85_RS00490	COG0604	alcohol dehydrogenase
NXY85_RS00495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NXY85_RS00500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS00505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS00510	COG0406	alpha-ribazole phosphatase activity
NXY85_RS00520	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS00525	COG2084	Dehydrogenase
NXY85_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS00535	COG1024	Enoyl-CoA hydratase
NXY85_RS00545	COG0840	transmembrane signaling receptor activity
NXY85_RS00550	COG0723	plastoquinol--plastocyanin reductase activity
NXY85_RS00550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXY85_RS00555	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS00570	COG4974	Belongs to the 'phage' integrase family
NXY85_RS00585	COG1192	Involved in chromosome partitioning
NXY85_RS00620	COG5444	nuclease activity
NXY85_RS00660	COG1309	transcriptional regulator
NXY85_RS00675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS00690	COG0398	Pfam SNARE associated Golgi protein
NXY85_RS00695	COG0681	Belongs to the peptidase S26 family
NXY85_RS00700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NXY85_RS00705	COG1846	Transcriptional regulator
NXY85_RS00710	COG3180	Ammonia monooxygenase
NXY85_RS00720	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NXY85_RS00725	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NXY85_RS00730	COG1074	ATP-dependent DNA helicase activity
NXY85_RS00735	COG0420	3'-5' exonuclease activity
NXY85_RS00740	COG0419	ATPase involved in DNA repair
NXY85_RS00745	COG1403	HNH endonuclease
NXY85_RS00780	COG2311	Membrane
NXY85_RS00790	COG5337	Spore coat protein CotH
NXY85_RS00795	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXY85_RS00805	COG1404	Belongs to the peptidase S8 family
NXY85_RS00815	COG0367	asparagine synthase
NXY85_RS00820	COG1562	ergosterol biosynthetic process
NXY85_RS00825	COG0534	Mate efflux family protein
NXY85_RS00830	COG2207	Transcriptional regulator
NXY85_RS00830	COG1917	Cupin 2, conserved barrel domain protein
NXY85_RS00835	COG0109	protoheme IX farnesyltransferase activity
NXY85_RS00840	COG1609	Transcriptional regulator
NXY85_RS00845	COG0673	inositol 2-dehydrogenase activity
NXY85_RS00850	COG2318	DinB family
NXY85_RS00865	COG1357	PFAM Pentapeptide repeats (8 copies)
NXY85_RS00875	COG2267	carboxylic ester hydrolase activity
NXY85_RS00880	COG0529	Catalyzes the synthesis of activated sulfate
NXY85_RS00885	COG2046	Belongs to the sulfate adenylyltransferase family
NXY85_RS00890	COG0175	sulfate reduction
NXY85_RS00895	COG2045	Belongs to the ComB family
NXY85_RS00900	COG1809	phosphosulfolactate synthase activity
NXY85_RS00905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS00910	COG4948	Mandelate Racemase Muconate Lactonizing
NXY85_RS00915	COG2814	Major facilitator Superfamily
NXY85_RS00920	COG0454	-acetyltransferase
NXY85_RS00925	COG2153	protein acetylation
NXY85_RS00930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXY85_RS00930	COG0646	methionine synthase
NXY85_RS00940	COG2996	Protein conserved in bacteria
NXY85_RS00955	COG1307	EDD domain protein, DegV family
NXY85_RS00960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS00980	COG0561	phosphatase activity
NXY85_RS00985	COG1073	alpha beta
NXY85_RS00990	COG2151	metal-sulfur cluster biosynthetic enzyme
NXY85_RS01000	COG0277	FAD linked oxidase domain protein
NXY85_RS01005	COG2271	Major facilitator Superfamily
NXY85_RS01010	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXY85_RS01015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NXY85_RS01025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXY85_RS01030	COG0505	Belongs to the CarA family
NXY85_RS01035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXY85_RS01040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXY85_RS01055	COG2267	carboxylic ester hydrolase activity
NXY85_RS01065	COG1744	ABC transporter substrate-binding protein PnrA-like
NXY85_RS01080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXY85_RS01085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXY85_RS01090	COG5504	Zn-dependent protease
NXY85_RS01095	COG0444	Belongs to the ABC transporter superfamily
NXY85_RS01100	COG4608	Belongs to the ABC transporter superfamily
NXY85_RS01110	COG0601	transmembrane transport
NXY85_RS01115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NXY85_RS01125	COG0180	Tryptophanyl-tRNA synthetase
NXY85_RS01130	COG4166	transmembrane transport
NXY85_RS01135	COG0601	transmembrane transport
NXY85_RS01140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NXY85_RS01145	COG0444	Belongs to the ABC transporter superfamily
NXY85_RS01150	COG4608	Belongs to the ABC transporter superfamily
NXY85_RS01165	COG0456	acetyltransferase
NXY85_RS01170	COG1393	Belongs to the ArsC family
NXY85_RS01175	COG0861	Integral membrane protein TerC family
NXY85_RS01185	COG4862	establishment of competence for transformation
NXY85_RS01190	COG4469	Competence protein
NXY85_RS01195	COG1164	Oligoendopeptidase f
NXY85_RS01205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NXY85_RS01210	COG2346	COG2346, Truncated hemoglobins
NXY85_RS01215	COG0741	lytic transglycosylase activity
NXY85_RS01220	COG4116	CYTH
NXY85_RS01230	COG2357	RelA SpoT domain protein
NXY85_RS01235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXY85_RS01240	COG0564	pseudouridine synthase activity
NXY85_RS01250	COG0569	domain protein
NXY85_RS01250	COG0475	glutathione-regulated potassium exporter activity
NXY85_RS01255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NXY85_RS01260	COG0352	thiamine-phosphate diphosphorylase activity
NXY85_RS01265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXY85_RS01270	COG2104	thiamine diphosphate biosynthetic process
NXY85_RS01275	COG2022	thiamine diphosphate biosynthetic process
NXY85_RS01280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXY85_RS01285	COG0351	phosphomethylpyrimidine kinase
NXY85_RS01290	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXY85_RS01345	COG0210	DNA helicase
NXY85_RS01365	COG2153	protein acetylation
NXY85_RS01375	COG2382	esterase
NXY85_RS01380	COG0626	cystathionine gamma-synthase activity
NXY85_RS01385	COG0626	cystathionine gamma-synthase activity
NXY85_RS01390	COG5505	Protein of unknown function (DUF819)
NXY85_RS01425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NXY85_RS01455	COG3209	COG3209 Rhs family protein
NXY85_RS01460	COG1285	pathogenesis
NXY85_RS01480	COG0726	polysaccharide deacetylase
NXY85_RS01490	COG2205	protein histidine kinase activity
NXY85_RS01500	COG3383	formate dehydrogenase (NAD+) activity
NXY85_RS01505	COG2427	Protein of unknown function (DUF1641)
NXY85_RS01515	COG1051	belongs to the nudix hydrolase family
NXY85_RS01525	COG2124	cytochrome p450
NXY85_RS01530	COG1819	glycosyl
NXY85_RS01550	COG1587	Uroporphyrinogen-III synthase
NXY85_RS01560	COG0390	transport system, permease component
NXY85_RS01565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXY85_RS01570	COG0697	spore germination
NXY85_RS01575	COG4297	protein containing double-stranded beta helix domain
NXY85_RS01585	COG1252	NADH dehydrogenase
NXY85_RS01590	COG1904	glucuronate isomerase
NXY85_RS01595	COG2211	Major facilitator Superfamily
NXY85_RS01600	COG1609	Transcriptional regulator
NXY85_RS01605	COG0246	Mannitol dehydrogenase
NXY85_RS01610	COG2721	sulfolactate sulfo-lyase activity
NXY85_RS01615	COG0730	response to heat
NXY85_RS01625	COG2318	DinB family
NXY85_RS01630	COG0457	Tetratricopeptide repeat
NXY85_RS01640	COG1388	LysM domain
NXY85_RS01640	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS01640	COG5632	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS01650	COG4195	phage-related replication protein
NXY85_RS01655	COG2856	Zn peptidase
NXY85_RS01660	COG1396	sequence-specific DNA binding
NXY85_RS01670	COG1522	sequence-specific DNA binding
NXY85_RS01675	COG1484	DNA-dependent DNA replication
NXY85_RS01695	COG1595	DNA-templated transcription, initiation
NXY85_RS01700	COG3728	DNA packaging
NXY85_RS01700	COG5484	DNA packaging
NXY85_RS01705	COG1783	phage Terminase large subunit
NXY85_RS01710	COG5518	Phage portal protein
NXY85_RS01715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NXY85_RS01720	COG4653	Phage capsid family
NXY85_RS01770	COG5412	phage tail tape measure protein
NXY85_RS01770	COG5412	phage tail tape measure protein
NXY85_RS01770	COG3953	SLT domain
NXY85_RS01770	COG5412	phage tail tape measure protein
NXY85_RS01770	COG3953	SLT domain
NXY85_RS01770	COG3953	SLT domain
NXY85_RS01775	COG1652	LysM domain
NXY85_RS01780	COG4193	domain, Protein
NXY85_RS01795	COG3628	GPW Gp25 family protein
NXY85_RS01800	COG3299	homolog of phage Mu protein gp47
NXY85_RS01805	COG3778	Protein conserved in bacteria
NXY85_RS01845	COG5632	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS01845	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS01865	COG0306	phosphate transporter
NXY85_RS01870	COG1392	Phosphate transport regulator
NXY85_RS01875	COG0531	amino acid
NXY85_RS01880	COG0346	lactoylglutathione lyase activity
NXY85_RS01885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NXY85_RS01890	COG0463	Glycosyl transferase, family 2
NXY85_RS01900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY85_RS01905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXY85_RS01910	COG2362	D-Aminopeptidase
NXY85_RS01915	COG0601	transmembrane transport
NXY85_RS01920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NXY85_RS01925	COG0444	Belongs to the ABC transporter superfamily
NXY85_RS01930	COG4166	transmembrane transport
NXY85_RS01935	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXY85_RS01940	COG4948	Mandelate Racemase Muconate Lactonizing
NXY85_RS01945	COG0791	NLP P60 protein
NXY85_RS01950	COG4608	Belongs to the ABC transporter superfamily
NXY85_RS01955	COG2706	6-phosphogluconolactonase activity
NXY85_RS01960	COG1834	amidinotransferase
NXY85_RS01965	COG1607	acyl-coa hydrolase
NXY85_RS01970	COG2323	membrane
NXY85_RS01975	COG1695	Transcriptional regulator
NXY85_RS01990	COG2318	DinB family
NXY85_RS02000	COG2076	Multidrug Resistance protein
NXY85_RS02005	COG2076	Multidrug Resistance protein
NXY85_RS02010	COG0788	formyltetrahydrofolate deformylase activity
NXY85_RS02015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NXY85_RS02020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXY85_RS02025	COG1764	response to oxidative stress
NXY85_RS02030	COG1846	Transcriptional regulator
NXY85_RS02035	COG1764	response to oxidative stress
NXY85_RS02050	COG0457	Tetratricopeptide repeat
NXY85_RS02050	COG0463	Glycosyl transferase, family 2
NXY85_RS02060	COG0590	tRNA wobble adenosine to inosine editing
NXY85_RS02070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NXY85_RS02075	COG1404	Belongs to the peptidase S8 family
NXY85_RS02080	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS02085	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NXY85_RS02090	COG1122	ATPase activity
NXY85_RS02095	COG4721	ABC-type cobalt transport system, permease component
NXY85_RS02105	COG0745	RESPONSE REGULATOR receiver
NXY85_RS02110	COG3850	Histidine kinase
NXY85_RS02110	COG5002	protein histidine kinase activity
NXY85_RS02115	COG3212	peptidase
NXY85_RS02120	COG3212	peptidase
NXY85_RS02130	COG2239	Acts as a magnesium transporter
NXY85_RS02135	COG0789	Transcriptional regulator
NXY85_RS02150	COG1846	Transcriptional regulator
NXY85_RS02155	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXY85_RS02160	COG0726	polysaccharide deacetylase
NXY85_RS02165	COG1408	metallophosphoesterase
NXY85_RS02180	COG0463	Glycosyl transferase, family 2
NXY85_RS02185	COG1793	dna ligase
NXY85_RS02185	COG3285	dna ligase
NXY85_RS02190	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NXY85_RS02210	COG0586	Pfam SNARE associated Golgi protein
NXY85_RS02220	COG1191	sigma factor activity
NXY85_RS02240	COG0501	Belongs to the peptidase M48B family
NXY85_RS02245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXY85_RS02250	COG2323	membrane
NXY85_RS02265	COG3594	Acyltransferase
NXY85_RS02270	COG5002	protein histidine kinase activity
NXY85_RS02275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXY85_RS02290	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NXY85_RS02295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXY85_RS02300	COG0436	Aminotransferase
NXY85_RS02305	COG1850	ribulose-bisphosphate carboxylase activity
NXY85_RS02315	COG0235	Class ii aldolase
NXY85_RS02320	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NXY85_RS02325	COG3339	Conserved Protein
NXY85_RS02340	COG3852	Histidine kinase
NXY85_RS02345	COG1846	Transcriptional regulator
NXY85_RS02350	COG1360	Flagellar Motor Protein
NXY85_RS02355	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NXY85_RS02360	COG0542	response to heat
NXY85_RS02365	COG3949	Membrane
NXY85_RS02380	COG0720	synthase
NXY85_RS02385	COG0602	queuosine metabolic process
NXY85_RS02390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXY85_RS02395	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS02410	COG4873	Protein conserved in bacteria
NXY85_RS02420	COG3773	Cell wall hydrolase
NXY85_RS02425	COG2244	polysaccharide biosynthetic process
NXY85_RS02430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS02435	COG2217	Heavy metal translocating P-type atpase
NXY85_RS02445	COG0006	proline dipeptidase activity
NXY85_RS02455	COG1609	Transcriptional regulator
NXY85_RS02460	COG3711	transcriptional antiterminator
NXY85_RS02465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS02465	COG1263	PTS System
NXY85_RS02465	COG2190	(PTS) system
NXY85_RS02470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS02475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXY85_RS02485	COG1533	DNA photolyase activity
NXY85_RS02495	COG0840	transmembrane signaling receptor activity
NXY85_RS02500	COG2084	Dehydrogenase
NXY85_RS02505	COG2340	Cysteine-rich secretory protein family
NXY85_RS02510	COG0768	penicillin binding
NXY85_RS02515	COG4191	Histidine kinase
NXY85_RS02520	COG0436	Aminotransferase
NXY85_RS02530	COG0835	chemotaxis
NXY85_RS02530	COG0784	Response regulator, receiver
NXY85_RS02540	COG2814	Major facilitator Superfamily
NXY85_RS02545	COG1376	ErfK ybiS ycfS ynhG family protein
NXY85_RS02550	COG1408	metallophosphoesterase
NXY85_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS02560	COG2200	EAL domain
NXY85_RS02565	COG3546	catalase activity
NXY85_RS02570	COG4703	Protein of unknown function (DUF1797)
NXY85_RS02575	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NXY85_RS02585	COG0517	IMP dehydrogenase activity
NXY85_RS02590	COG0583	DNA-binding transcription factor activity
NXY85_RS02595	COG0716	FMN binding
NXY85_RS02605	COG0716	FMN binding
NXY85_RS02610	COG2171	N-acyltransferase activity
NXY85_RS02615	COG1473	amidohydrolase
NXY85_RS02625	COG0668	transmembrane transport
NXY85_RS02630	COG0450	alkyl hydroperoxide reductase
NXY85_RS02635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS02650	COG0746	molybdenum cofactor guanylyltransferase activity
NXY85_RS02655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXY85_RS02660	COG0303	'Molybdopterin
NXY85_RS02665	COG1763	Mo-molybdopterin cofactor biosynthetic process
NXY85_RS02670	COG0314	molybdopterin synthase activity
NXY85_RS02675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NXY85_RS02680	COG1132	(ABC) transporter
NXY85_RS02685	COG1132	(ABC) transporter
NXY85_RS02695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY85_RS02700	COG1136	(ABC) transporter
NXY85_RS02705	COG0577	efflux transmembrane transporter activity
NXY85_RS02710	COG1349	DNA-binding transcription factor activity
NXY85_RS02715	COG1105	Belongs to the carbohydrate kinase PfkB family
NXY85_RS02720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NXY85_RS02720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NXY85_RS02720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS02725	COG0681	Belongs to the peptidase S26 family
NXY85_RS02735	COG0488	(ABC) transporter
NXY85_RS02740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXY85_RS02745	COG2309	aminopeptidase activity
NXY85_RS02755	COG1077	Cell shape determining protein MreB Mrl
NXY85_RS02760	COG2002	toxin-antitoxin pair type II binding
NXY85_RS02765	COG3852	Histidine kinase
NXY85_RS02770	COG2105	PFAM AIG2 family protein
NXY85_RS02770	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
NXY85_RS02775	COG0569	domain protein
NXY85_RS02780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NXY85_RS02785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NXY85_RS02795	COG0561	phosphatase activity
NXY85_RS02800	COG0242	peptide deformylase activity
NXY85_RS02810	COG0497	DNA recombination
NXY85_RS02815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NXY85_RS02820	COG0022	dehydrogenase e1 component
NXY85_RS02825	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXY85_RS02830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXY85_RS02835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS02850	COG1982	Orn Lys Arg decarboxylase major
NXY85_RS02855	COG4476	Belongs to the UPF0223 family
NXY85_RS02860	COG4493	Belongs to the UPF0637 family
NXY85_RS02870	COG0483	inositol monophosphate 1-phosphatase activity
NXY85_RS02880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NXY85_RS02910	COG1217	gtp-binding protein TYPA
NXY85_RS02920	COG4896	Protein conserved in bacteria
NXY85_RS02930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXY85_RS02935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NXY85_RS02940	COG2066	Belongs to the glutaminase family
NXY85_RS02945	COG4838	Belongs to the UPF0358 family
NXY85_RS02950	COG0772	Belongs to the SEDS family
NXY85_RS02955	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NXY85_RS02960	COG1612	heme a metabolic process
NXY85_RS02970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NXY85_RS02970	COG2010	Cytochrome c
NXY85_RS02975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NXY85_RS02980	COG1845	cytochrome c oxidase, subunit III
NXY85_RS02985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NXY85_RS02990	COG3336	cytochrome c oxidase
NXY85_RS03000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NXY85_RS03005	COG2340	Cysteine-rich secretory protein family
NXY85_RS03025	COG3679	Belongs to the UPF0342 family
NXY85_RS03030	COG4471	UPF0298 protein
NXY85_RS03040	COG0742	ribosomal rna small subunit methyltransferase
NXY85_RS03045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXY85_RS03050	COG3314	Sporulation integral membrane protein YlbJ
NXY85_RS03055	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXY85_RS03060	COG3480	Lon protease (S16) C-terminal proteolytic domain
NXY85_RS03065	COG1323	Belongs to the UPF0348 family
NXY85_RS03075	COG1399	metal-binding, possibly nucleic acid-binding protein
NXY85_RS03095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXY85_RS03100	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NXY85_RS03105	COG2001	Belongs to the MraZ family
NXY85_RS03110	COG0275	rRNA processing
NXY85_RS03115	COG4839	cell division protein FtsL
NXY85_RS03120	COG0768	penicillin binding
NXY85_RS03125	COG0768	penicillin binding
NXY85_RS03130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXY85_RS03135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXY85_RS03140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXY85_RS03145	COG0772	Belongs to the SEDS family
NXY85_RS03150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXY85_RS03155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXY85_RS03160	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NXY85_RS03165	COG3879	Bacterial protein of unknown function (DUF881)
NXY85_RS03170	COG3879	Bacterial protein of unknown function (DUF881)
NXY85_RS03175	COG3856	small basic protein
NXY85_RS03180	COG0849	cell division
NXY85_RS03185	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXY85_RS03190	COG1404	Belongs to the peptidase S8 family
NXY85_RS03190	COG4412	M6 family metalloprotease domain protein
NXY85_RS03200	COG1191	sigma factor activity
NXY85_RS03205	COG1191	sigma factor activity
NXY85_RS03210	COG1119	ATPase activity
NXY85_RS03215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXY85_RS03220	COG1873	PFAM PRC-barrel domain
NXY85_RS03225	COG1496	oxidoreductase activity
NXY85_RS03230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXY85_RS03235	COG1799	cell septum assembly
NXY85_RS03240	COG0762	integral membrane protein
NXY85_RS03245	COG2302	S4 RNA-binding domain
NXY85_RS03250	COG3599	regulation of cell shape
NXY85_RS03255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXY85_RS03260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NXY85_RS03265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXY85_RS03270	COG0564	pseudouridine synthase activity
NXY85_RS03280	COG2233	PERMEase
NXY85_RS03285	COG0540	Belongs to the ATCase OTCase family
NXY85_RS03290	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NXY85_RS03295	COG0505	Belongs to the CarA family
NXY85_RS03300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXY85_RS03305	COG0543	2 iron, 2 sulfur cluster binding
NXY85_RS03310	COG0167	dihydroorotate dehydrogenase activity
NXY85_RS03315	COG0284	orotidine-5'-phosphate decarboxylase activity
NXY85_RS03320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXY85_RS03325	COG0175	sulfate reduction
NXY85_RS03330	COG0306	phosphate transporter
NXY85_RS03335	COG2046	Belongs to the sulfate adenylyltransferase family
NXY85_RS03340	COG0529	Catalyzes the synthesis of activated sulfate
NXY85_RS03345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NXY85_RS03350	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NXY85_RS03355	COG1648	precorrin-2 dehydrogenase activity
NXY85_RS03360	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NXY85_RS03365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXY85_RS03370	COG1561	YicC-like family, N-terminal region
NXY85_RS03380	COG0194	GDP metabolic process
NXY85_RS03385	COG1758	RNA polymerase activity
NXY85_RS03390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NXY85_RS03395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXY85_RS03400	COG0242	peptide deformylase activity
NXY85_RS03405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXY85_RS03410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NXY85_RS03410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXY85_RS03420	COG0631	protein serine/threonine phosphatase activity
NXY85_RS03425	COG0515	serine threonine protein kinase
NXY85_RS03425	COG2815	serine threonine protein kinase
NXY85_RS03430	COG1162	GTPase activity
NXY85_RS03435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXY85_RS03440	COG1564	THIamine pyrophosphokinase
NXY85_RS03450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXY85_RS03455	COG1302	Protein conserved in bacteria
NXY85_RS03460	COG1461	Dihydroxyacetone kinase
NXY85_RS03465	COG1760	l-serine dehydratase
NXY85_RS03470	COG1760	l-serine dehydratase
NXY85_RS03475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXY85_RS03480	COG1349	DNA-binding transcription factor activity
NXY85_RS03480	COG2050	protein possibly involved in aromatic compounds catabolism
NXY85_RS03490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXY85_RS03495	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS03505	COG0571	ribonuclease III activity
NXY85_RS03510	COG1196	nuclear chromosome segregation
NXY85_RS03515	COG0552	protein localization to endoplasmic reticulum
NXY85_RS03520	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NXY85_RS03525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXY85_RS03530	COG0228	four-way junction DNA binding
NXY85_RS03535	COG1837	Belongs to the UPF0109 family
NXY85_RS03545	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXY85_RS03560	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NXY85_RS03565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXY85_RS03575	COG2257	FlhB HrpN YscU SpaS Family
NXY85_RS03585	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXY85_RS03590	COG0758	DNA mediated transformation
NXY85_RS03595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXY85_RS03600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NXY85_RS03605	COG4974	Belongs to the 'phage' integrase family
NXY85_RS03610	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NXY85_RS03615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NXY85_RS03625	COG1815	bacterial-type flagellum-dependent cell motility
NXY85_RS03630	COG1558	bacterial-type flagellum-dependent cell motility
NXY85_RS03635	COG1677	Flagellar hook-basal body complex protein FliE
NXY85_RS03640	COG1766	The M ring may be actively involved in energy transduction
NXY85_RS03645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NXY85_RS03650	COG1317	bacterial-type flagellum organization
NXY85_RS03655	COG1157	protein secretion by the type III secretion system
NXY85_RS03660	COG2882	bacterial-type flagellum organization
NXY85_RS03665	COG3334	PFAM MgtE intracellular
NXY85_RS03670	COG3144	bacterial-type flagellum assembly
NXY85_RS03675	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NXY85_RS03680	COG4786	Flagellar basal body rod
NXY85_RS03685	COG1582	Flagellar protein (FlbD)
NXY85_RS03690	COG1580	Controls the rotational direction of flagella during chemotaxis
NXY85_RS03695	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NXY85_RS03700	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NXY85_RS03700	COG1776	CheC inhibitor of MCP methylation
NXY85_RS03705	COG2201	protein-glutamate methylesterase activity
NXY85_RS03710	COG3190	flagellar
NXY85_RS03715	COG1338	Plays a role in the flagellum-specific transport system
NXY85_RS03720	COG1987	bacterial-type flagellum assembly
NXY85_RS03725	COG1684	flagellar biosynthetic protein fliR
NXY85_RS03730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NXY85_RS03735	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NXY85_RS03740	COG1419	protein localization to endoplasmic reticulum
NXY85_RS03745	COG0455	bacterial-type flagellum organization
NXY85_RS03750	COG2201	protein-glutamate methylesterase activity
NXY85_RS03755	COG0643	Histidine kinase
NXY85_RS03755	COG2198	Histidine kinase
NXY85_RS03760	COG0835	chemotaxis
NXY85_RS03765	COG1776	CheC inhibitor of MCP methylation
NXY85_RS03770	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NXY85_RS03775	COG1191	sigma factor activity
NXY85_RS03790	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXY85_RS03795	COG0528	UMP kinase activity
NXY85_RS03800	COG0233	cytoplasmic translational termination
NXY85_RS03805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXY85_RS03810	COG4589	Belongs to the CDS family
NXY85_RS03815	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXY85_RS03820	COG0750	zinc metalloprotease
NXY85_RS03825	COG0442	prolyl-tRNA aminoacylation
NXY85_RS03830	COG2176	DNA-directed DNA polymerase activity
NXY85_RS03835	COG0779	Required for maturation of 30S ribosomal subunits
NXY85_RS03840	COG0195	Participates in both transcription termination and antitermination
NXY85_RS03845	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NXY85_RS03850	COG1358	cellular component organization or biogenesis
NXY85_RS03855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXY85_RS03860	COG1550	Protein conserved in bacteria
NXY85_RS03865	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXY85_RS03870	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXY85_RS03875	COG0196	riboflavin kinase activity
NXY85_RS03885	COG1185	polyribonucleotide nucleotidyltransferase activity
NXY85_RS03890	COG0726	polysaccharide deacetylase
NXY85_RS03895	COG0612	Peptidase, M16
NXY85_RS03900	COG1873	PFAM PRC-barrel domain
NXY85_RS03905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXY85_RS03910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NXY85_RS03915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXY85_RS03920	COG0527	aspartate kinase activity
NXY85_RS03930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NXY85_RS03935	COG0740	serine-type endopeptidase activity
NXY85_RS03945	COG4980	gas vesicle protein
NXY85_RS03945	COG1674	ftsk spoiiie
NXY85_RS03950	COG2188	Transcriptional regulator
NXY85_RS03955	COG2814	Major facilitator Superfamily
NXY85_RS03965	COG0612	Peptidase, M16
NXY85_RS03970	COG0612	Peptidase, M16
NXY85_RS03975	COG0300	oxidoreductase activity
NXY85_RS03990	COG1426	Protein conserved in bacteria
NXY85_RS03995	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXY85_RS04000	COG1546	Belongs to the CinA family
NXY85_RS04000	COG1058	Belongs to the CinA family
NXY85_RS04005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXY85_RS04010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NXY85_RS04020	COG1692	metallophosphoesterase
NXY85_RS04025	COG2359	stage V sporulation protein S
NXY85_RS04030	COG1063	alcohol dehydrogenase
NXY85_RS04035	COG0156	8-amino-7-oxononanoate synthase activity
NXY85_RS04050	COG4550	Control of competence regulator ComK, YlbF/YmcA
NXY85_RS04060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXY85_RS04065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXY85_RS04080	COG3226	Transcriptional regulator
NXY85_RS04085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY85_RS04090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXY85_RS04095	COG3321	synthase
NXY85_RS04100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXY85_RS04100	COG2070	2-Nitropropane dioxygenase
NXY85_RS04105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXY85_RS04110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXY85_RS04115	COG3425	synthase
NXY85_RS04120	COG1024	Enoyl-CoA hydratase
NXY85_RS04125	COG1024	Enoyl-CoA hydratase
NXY85_RS04130	COG3321	synthase
NXY85_RS04130	COG0318	PFAM AMP-dependent synthetase and ligase
NXY85_RS04130	COG0300	oxidoreductase activity
NXY85_RS04130	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS04130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXY85_RS04135	COG4221	oxidoreductase activity
NXY85_RS04135	COG0300	oxidoreductase activity
NXY85_RS04135	COG3321	synthase
NXY85_RS04140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXY85_RS04140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY85_RS04140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS04140	COG3321	synthase
NXY85_RS04145	COG3321	synthase
NXY85_RS04145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS04145	COG4221	oxidoreductase activity
NXY85_RS04150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXY85_RS04150	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NXY85_RS04150	COG3321	synthase
NXY85_RS04150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXY85_RS04155	COG2124	cytochrome p450
NXY85_RS04165	COG1404	Belongs to the peptidase S8 family
NXY85_RS04175	COG4195	phage-related replication protein
NXY85_RS04180	COG1764	response to oxidative stress
NXY85_RS04190	COG2076	Multidrug Resistance protein
NXY85_RS04210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXY85_RS04235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NXY85_RS04240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NXY85_RS04245	COG4112	unkown
NXY85_RS04250	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS04255	COG0464	growth
NXY85_RS04260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXY85_RS04265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NXY85_RS04270	COG0789	Transcriptional regulator
NXY85_RS04275	COG0174	glutamine synthetase
NXY85_RS04320	COG2851	Citrate transporter
NXY85_RS04325	COG0456	acetyltransferase
NXY85_RS04360	COG3391	amine dehydrogenase activity
NXY85_RS04370	COG0657	acetylesterase activity
NXY85_RS04380	COG1011	Hydrolase
NXY85_RS04395	COG2318	DinB family
NXY85_RS04400	COG2367	Beta-lactamase
NXY85_RS04425	COG2720	vancomycin resistance protein
NXY85_RS04430	COG5553	Cysteine dioxygenase type I
NXY85_RS04445	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS04460	COG0456	acetyltransferase
NXY85_RS04465	COG0789	Transcriptional regulator
NXY85_RS04465	COG4978	Transcriptional regulator
NXY85_RS04470	COG2030	dehydratase
NXY85_RS04485	COG2135	peptidase activity
NXY85_RS04500	COG0457	Tetratricopeptide repeat
NXY85_RS04515	COG1131	(ABC) transporter
NXY85_RS04565	COG4195	phage-related replication protein
NXY85_RS04570	COG3619	membrane
NXY85_RS04590	COG4195	phage-related replication protein
NXY85_RS04615	COG5577	PFAM Coat F domain
NXY85_RS04625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NXY85_RS04630	COG1388	LysM domain
NXY85_RS04635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXY85_RS04640	COG4224	UPF0291 protein
NXY85_RS04645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NXY85_RS04655	COG3763	UPF0154 protein
NXY85_RS04665	COG0785	Cytochrome C biogenesis protein
NXY85_RS04670	COG2201	protein-glutamate methylesterase activity
NXY85_RS04675	COG4846	Membrane protein involved in cytochrome C biogenesis
NXY85_RS04685	COG0071	Belongs to the small heat shock protein (HSP20) family
NXY85_RS04700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NXY85_RS04705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS04725	COG0824	Thioesterase
NXY85_RS04735	COG4841	protein insertion into membrane
NXY85_RS04740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NXY85_RS04745	COG1832	CoA-binding protein
NXY85_RS04750	COG0187	DNA topoisomerase II activity
NXY85_RS04755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NXY85_RS04770	COG1115	amino acid carrier protein
NXY85_RS04780	COG2246	polysaccharide biosynthetic process
NXY85_RS04785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NXY85_RS04790	COG0586	Pfam SNARE associated Golgi protein
NXY85_RS04795	COG2404	hydrolase activity, acting on ester bonds
NXY85_RS04800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXY85_RS04805	COG1024	Enoyl-CoA hydratase
NXY85_RS04810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXY85_RS04815	COG0511	ligase activity, forming carbon-carbon bonds
NXY85_RS04820	COG0439	Biotin carboxylase
NXY85_RS04825	COG0318	PFAM AMP-dependent synthetase and ligase
NXY85_RS04830	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS04835	COG1649	PFAM Uncharacterised BCR, COG1649
NXY85_RS04845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04845	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NXY85_RS04850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS04870	COG1017	nitric oxide dioxygenase activity
NXY85_RS04870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NXY85_RS04875	COG2027	D-alanyl-D-alanine carboxypeptidase
NXY85_RS04880	COG2017	converts alpha-aldose to the beta-anomer
NXY85_RS04900	COG0582	viral genome integration into host DNA
NXY85_RS04905	COG0166	Belongs to the GPI family
NXY85_RS04910	COG0405	Gamma-glutamyltransferase
NXY85_RS04920	COG0604	alcohol dehydrogenase
NXY85_RS04925	COG0493	'glutamate synthase
NXY85_RS04930	COG0070	glutamate synthase
NXY85_RS04930	COG0067	glutamate synthase
NXY85_RS04930	COG0069	glutamate synthase activity
NXY85_RS04935	COG0583	DNA-binding transcription factor activity
NXY85_RS04940	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NXY85_RS04975	COG0693	protein deglycase activity
NXY85_RS04985	COG0300	oxidoreductase activity
NXY85_RS04990	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NXY85_RS04995	COG2318	DinB family
NXY85_RS05000	COG2814	Major facilitator Superfamily
NXY85_RS05005	COG1070	Carbohydrate kinase
NXY85_RS05010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXY85_RS05015	COG0243	molybdopterin cofactor binding
NXY85_RS05030	COG1309	transcriptional regulator
NXY85_RS05035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY85_RS05040	COG0662	Cupin 2, conserved barrel domain protein
NXY85_RS05040	COG2207	Transcriptional regulator
NXY85_RS05050	COG1309	transcriptional regulator
NXY85_RS05060	COG3708	Transcriptional regulator
NXY85_RS05065	COG2378	regulation of single-species biofilm formation
NXY85_RS05075	COG0640	Transcriptional regulator
NXY85_RS05080	COG0741	lytic transglycosylase activity
NXY85_RS05085	COG2322	membrane
NXY85_RS05100	COG3239	Fatty acid desaturase
NXY85_RS05105	COG4585	Histidine kinase
NXY85_RS05110	COG2197	response regulator
NXY85_RS05120	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS05125	COG3584	3D domain protein
NXY85_RS05125	COG1388	LysM domain
NXY85_RS05130	COG0514	ATP-dependent DNA helicase (RecQ)
NXY85_RS05140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NXY85_RS05145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NXY85_RS05165	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS05170	COG1657	PFAM Prenyltransferase squalene oxidase
NXY85_RS05175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NXY85_RS05180	COG0733	neurotransmitter:sodium symporter activity
NXY85_RS05185	COG0385	Bile acid
NXY85_RS05190	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXY85_RS05195	COG0567	Dehydrogenase, E1 component
NXY85_RS05200	COG4548	von Willebrand factor, type A
NXY85_RS05205	COG0714	Associated with various cellular activities
NXY85_RS05210	COG2032	superoxide dismutase activity
NXY85_RS05215	COG0791	NLP P60 protein
NXY85_RS05215	COG1388	LysM domain
NXY85_RS05220	COG1819	glycosyl
NXY85_RS05225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXY85_RS05230	COG0534	Mate efflux family protein
NXY85_RS05245	COG0457	Tetratricopeptide repeat
NXY85_RS05255	COG5444	nuclease activity
NXY85_RS05275	COG5632	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS05275	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS05280	COG4824	toxin secretion phage lysis holin
NXY85_RS05300	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS05305	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXY85_RS05315	COG3953	SLT domain
NXY85_RS05315	COG5280	Phage tail tape measure protein TP901
NXY85_RS05425	COG1595	DNA-templated transcription, initiation
NXY85_RS05450	COG0305	Participates in initiation and elongation during chromosome replication
NXY85_RS05510	COG0582	viral genome integration into host DNA
NXY85_RS05520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NXY85_RS05525	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NXY85_RS05535	COG2962	Rard protein
NXY85_RS05555	COG1942	4-Oxalocrotonate Tautomerase
NXY85_RS05560	COG1733	regulation of RNA biosynthetic process
NXY85_RS05565	COG0778	Nitroreductase
NXY85_RS05570	COG0400	carboxylic ester hydrolase activity
NXY85_RS05575	COG0346	lactoylglutathione lyase activity
NXY85_RS05585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS05590	COG0793	Belongs to the peptidase S41A family
NXY85_RS05590	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS05595	COG2226	methyltransferase
NXY85_RS05605	COG1876	peptidase activity
NXY85_RS05610	COG0813	purine-nucleoside phosphorylase activity
NXY85_RS05625	COG0671	phosphoesterase, PA-phosphatase related
NXY85_RS05655	COG1509	lysine 2,3-aminomutase activity
NXY85_RS05660	COG0456	acetyltransferase
NXY85_RS05665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXY85_RS05670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NXY85_RS05675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NXY85_RS05680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXY85_RS05690	COG0456	acetyltransferase
NXY85_RS05695	COG0463	Glycosyl transferase, family 2
NXY85_RS05710	COG4641	Protein conserved in bacteria
NXY85_RS05715	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NXY85_RS05725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXY85_RS05740	COG0366	Alpha amylase catalytic
NXY85_RS05745	COG3397	chitin binding
NXY85_RS05755	COG3655	Transcriptional regulator
NXY85_RS05760	COG3739	integral membrane protein
NXY85_RS05770	COG3708	Transcriptional regulator
NXY85_RS05770	COG2207	Transcriptional regulator
NXY85_RS05790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXY85_RS05795	COG1846	Transcriptional regulator
NXY85_RS05800	COG0534	Mate efflux family protein
NXY85_RS05810	COG4698	Protein conserved in bacteria
NXY85_RS05815	COG2755	lipolytic protein G-D-S-L family
NXY85_RS05820	COG1999	signal sequence binding
NXY85_RS05830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NXY85_RS05835	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NXY85_RS05840	COG1272	protein, Hemolysin III
NXY85_RS05845	COG0204	Acyl-transferase
NXY85_RS05850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NXY85_RS05860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXY85_RS05870	COG2521	methyltransferase
NXY85_RS05870	COG2136	Putative SAM-dependent methyltransferase
NXY85_RS05885	COG1413	lyase activity
NXY85_RS05890	COG1418	mRNA catabolic process
NXY85_RS05895	COG0386	Belongs to the glutathione peroxidase family
NXY85_RS05900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXY85_RS05905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXY85_RS05910	COG1278	Cold shock
NXY85_RS05930	COG0328	RNA-DNA hybrid ribonuclease activity
NXY85_RS05935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NXY85_RS05940	COG0328	RNA-DNA hybrid ribonuclease activity
NXY85_RS05950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY85_RS05965	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NXY85_RS05975	COG1755	Isoprenylcysteine carboxyl methyltransferase
NXY85_RS05980	COG3424	synthase
NXY85_RS05985	COG2233	PERMEase
NXY85_RS05990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXY85_RS05995	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NXY85_RS06005	COG0800	Aldolase
NXY85_RS06010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY85_RS06015	COG1609	Transcriptional regulator
NXY85_RS06020	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXY85_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS06030	COG1199	ATP-dependent helicase activity
NXY85_RS06045	COG0116	Belongs to the methyltransferase superfamily
NXY85_RS06075	COG3359	exonuclease
NXY85_RS06080	COG1111	helicase
NXY85_RS06080	COG1205	dead DEAH box helicase
NXY85_RS06085	COG2190	(PTS) system
NXY85_RS06090	COG0071	Belongs to the small heat shock protein (HSP20) family
NXY85_RS06125	COG3331	DNA recombination
NXY85_RS06130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXY85_RS06130	COG4499	WXG100 protein secretion system (Wss), protein YukC
NXY85_RS06140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXY85_RS06145	COG3935	DnaD domain protein
NXY85_RS06150	COG0017	Asparaginyl-tRNA synthetase
NXY85_RS06155	COG0436	Aminotransferase
NXY85_RS06160	COG5353	protein conserved in bacteria
NXY85_RS06170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NXY85_RS06170	COG1199	ATP-dependent helicase activity
NXY85_RS06175	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXY85_RS06180	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXY85_RS06185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXY85_RS06190	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NXY85_RS06190	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NXY85_RS06195	COG0617	tRNA 3'-terminal CCA addition
NXY85_RS06200	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS06205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NXY85_RS06220	COG1694	Mazg nucleotide pyrophosphohydrolase
NXY85_RS06225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS06230	COG2140	Oxalate decarboxylase
NXY85_RS06240	COG4347	Protein of unknown function (DUF1405)
NXY85_RS06245	COG2010	Cytochrome c
NXY85_RS06245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NXY85_RS06250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NXY85_RS06255	COG0723	plastoquinol--plastocyanin reductase activity
NXY85_RS06265	COG5582	Belongs to the UPF0302 family
NXY85_RS06270	COG0457	Tetratricopeptide repeat
NXY85_RS06275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXY85_RS06280	COG0287	Prephenate dehydrogenase
NXY85_RS06285	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXY85_RS06290	COG0159	tryptophan synthase activity
NXY85_RS06310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXY85_RS06315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXY85_RS06320	COG4401	Chorismate mutase type I
NXY85_RS06325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXY85_RS06335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NXY85_RS06340	COG0105	UTP biosynthetic process
NXY85_RS06345	COG0142	geranyltranstransferase activity
NXY85_RS06355	COG0142	geranyltranstransferase activity
NXY85_RS06365	COG0302	gtp cyclohydrolase
NXY85_RS06370	COG0776	regulation of translation
NXY85_RS06375	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NXY85_RS06390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXY85_RS06395	COG1160	GTP binding
NXY85_RS06420	COG1304	FMN binding
NXY85_RS06425	COG0539	negative regulation of cytoplasmic translation
NXY85_RS06430	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXY85_RS06440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NXY85_RS06445	COG2959	enzyme of heme biosynthesis
NXY85_RS06450	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS06450	COG3773	Cell wall hydrolase
NXY85_RS06455	COG2339	peptidase activity
NXY85_RS06460	COG0492	ferredoxin-NADP+ reductase activity
NXY85_RS06465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXY85_RS06470	COG4862	establishment of competence for transformation
NXY85_RS06475	COG1408	metallophosphoesterase
NXY85_RS06485	COG1388	LysM domain
NXY85_RS06490	COG1266	CAAX protease self-immunity
NXY85_RS06495	COG0514	ATP-dependent DNA helicase (RecQ)
NXY85_RS06500	COG4955	Helix-turn-helix domain
NXY85_RS06505	COG1141	Ferredoxin
NXY85_RS06510	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NXY85_RS06515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXY85_RS06520	COG0710	3-dehydroquinate dehydratase activity
NXY85_RS06530	COG1595	DNA-templated transcription, initiation
NXY85_RS06535	COG5002	protein histidine kinase activity
NXY85_RS06540	COG0745	RESPONSE REGULATOR receiver
NXY85_RS06545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXY85_RS06550	COG1333	cytochrome c biogenesis protein
NXY85_RS06555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS06560	COG1187	pseudouridine synthase activity
NXY85_RS06565	COG0700	Nucleoside recognition
NXY85_RS06570	COG2715	membrane protein required for spore maturation
NXY85_RS06575	COG1686	Belongs to the peptidase S11 family
NXY85_RS06585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NXY85_RS06590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NXY85_RS06600	COG1547	Domain of unknown function (DUF309)
NXY85_RS06605	COG0456	acetyltransferase
NXY85_RS06610	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXY85_RS06615	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXY85_RS06615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXY85_RS06620	COG0307	riboflavin synthase, alpha
NXY85_RS06625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXY85_RS06625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXY85_RS06635	COG0681	Belongs to the peptidase S26 family
NXY85_RS06640	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NXY85_RS06650	COG1278	Cold shock
NXY85_RS06660	COG0673	inositol 2-dehydrogenase activity
NXY85_RS06680	COG2182	Extracellular solute-binding protein
NXY85_RS06685	COG1175	transmembrane transport
NXY85_RS06690	COG3833	ABC-type maltose transport systems, permease component
NXY85_RS06695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXY85_RS06710	COG3420	alginic acid biosynthetic process
NXY85_RS06720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXY85_RS06725	COG4086	secreted protein
NXY85_RS06730	COG0019	diaminopimelate decarboxylase activity
NXY85_RS06735	COG0697	spore germination
NXY85_RS06750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXY85_RS06770	COG1191	sigma factor activity
NXY85_RS06775	COG2172	sigma factor antagonist activity
NXY85_RS06780	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS06785	COG1686	Belongs to the peptidase S11 family
NXY85_RS06790	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXY85_RS06795	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NXY85_RS06800	COG4974	Belongs to the 'phage' integrase family
NXY85_RS06810	COG0735	belongs to the Fur family
NXY85_RS06815	COG1300	Membrane
NXY85_RS06825	COG0281	malic enzyme
NXY85_RS06830	COG1757	Na H antiporter
NXY85_RS06835	COG1027	Aspartate ammonia-lyase
NXY85_RS06840	COG0252	asparaginase activity
NXY85_RS06845	COG1396	sequence-specific DNA binding
NXY85_RS06850	COG1379	DNA repair
NXY85_RS06855	COG0494	nUDIX hydrolase
NXY85_RS06865	COG0667	Aldo Keto reductase
NXY85_RS06875	COG1073	alpha beta
NXY85_RS06885	COG4918	Iron-sulphur cluster biosynthesis
NXY85_RS06890	COG0456	acetyltransferase
NXY85_RS06890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NXY85_RS06895	COG2329	Antibiotic biosynthesis monooxygenase
NXY85_RS06900	COG0456	acetyltransferase
NXY85_RS06910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NXY85_RS06920	COG0628	permease
NXY85_RS06940	COG0346	lactoylglutathione lyase activity
NXY85_RS06945	COG1072	(Pantothenic acid kinase))
NXY85_RS06950	COG3048	D-serine ammonia-lyase activity
NXY85_RS06960	COG0300	oxidoreductase activity
NXY85_RS06965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY85_RS06970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXY85_RS06975	COG4187	Peptidase family M20/M25/M40
NXY85_RS06980	COG1902	pentaerythritol trinitrate reductase activity
NXY85_RS06985	COG0596	Alpha beta hydrolase
NXY85_RS06995	COG1234	tRNA 3'-trailer cleavage
NXY85_RS07000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXY85_RS07005	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXY85_RS07010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NXY85_RS07020	COG0706	membrane insertase activity
NXY85_RS07025	COG3361	conserved protein (COG2071)
NXY85_RS07030	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXY85_RS07035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXY85_RS07040	COG0346	lactoylglutathione lyase activity
NXY85_RS07050	COG1376	ErfK ybiS ycfS ynhG family protein
NXY85_RS07055	COG4129	membrane
NXY85_RS07060	COG1126	abc transporter atp-binding protein
NXY85_RS07065	COG0765	amino acid transport
NXY85_RS07070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY85_RS07080	COG1597	lipid kinase activity
NXY85_RS07090	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXY85_RS07095	COG0022	dehydrogenase e1 component
NXY85_RS07100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NXY85_RS07105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXY85_RS07110	COG3426	butyrate kinase activity
NXY85_RS07115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXY85_RS07120	COG0280	phosphate acetyltransferase
NXY85_RS07125	COG3290	protein histidine kinase activity
NXY85_RS07125	COG3829	transcription factor binding
NXY85_RS07135	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NXY85_RS07140	COG2079	MmgE PrpD family protein
NXY85_RS07145	COG0372	Belongs to the citrate synthase family
NXY85_RS07150	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS07155	COG1250	3-hydroxyacyl-CoA dehydrogenase
NXY85_RS07160	COG0183	Belongs to the thiolase family
NXY85_RS07165	COG0584	glycerophosphoryl diester phosphodiesterase
NXY85_RS07170	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS07180	COG1902	pentaerythritol trinitrate reductase activity
NXY85_RS07190	COG0745	RESPONSE REGULATOR receiver
NXY85_RS07195	COG0750	zinc metalloprotease
NXY85_RS07200	COG0497	DNA recombination
NXY85_RS07205	COG1438	arginine binding
NXY85_RS07210	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NXY85_RS07215	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXY85_RS07220	COG0142	geranyltranstransferase activity
NXY85_RS07225	COG1722	exodeoxyribonuclease VII activity
NXY85_RS07230	COG1570	exodeoxyribonuclease VII activity
NXY85_RS07235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXY85_RS07240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXY85_RS07245	COG1302	Protein conserved in bacteria
NXY85_RS07250	COG0439	Biotin carboxylase
NXY85_RS07255	COG0511	ligase activity, forming carbon-carbon bonds
NXY85_RS07295	COG3854	ATPases associated with a variety of cellular activities
NXY85_RS07305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXY85_RS07310	COG0006	proline dipeptidase activity
NXY85_RS07315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NXY85_RS07325	COG3872	metal-dependent enzyme
NXY85_RS07335	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXY85_RS07340	COG1321	iron dependent repressor
NXY85_RS07345	COG0095	Lipoate-protein ligase
NXY85_RS07350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NXY85_RS07355	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXY85_RS07360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXY85_RS07365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXY85_RS07370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXY85_RS07385	COG1396	sequence-specific DNA binding
NXY85_RS07395	COG0681	Belongs to the peptidase S26 family
NXY85_RS07420	COG4940	Competence protein ComGF
NXY85_RS07430	COG4970	Tfp pilus assembly protein FimT
NXY85_RS07435	COG4537	Required for transformation and DNA binding
NXY85_RS07440	COG1459	type II secretion system
NXY85_RS07445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NXY85_RS07450	COG0598	Magnesium transport protein CorA
NXY85_RS07455	COG1253	flavin adenine dinucleotide binding
NXY85_RS07460	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS07470	COG1393	Belongs to the ArsC family
NXY85_RS07480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY85_RS07490	COG0011	TIGRFAM Protein of
NXY85_RS07500	COG2866	Carboxypeptidase
NXY85_RS07505	COG1368	sulfuric ester hydrolase activity
NXY85_RS07510	COG1940	carbohydrate kinase activity
NXY85_RS07515	COG4483	Protein conserved in bacteria
NXY85_RS07520	COG0705	Rhomboid family
NXY85_RS07520	COG0457	Tetratricopeptide repeat
NXY85_RS07530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXY85_RS07540	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS07555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXY85_RS07560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXY85_RS07565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXY85_RS07570	COG0581	inorganic phosphate transmembrane transporter activity
NXY85_RS07575	COG0573	inorganic phosphate transmembrane transporter activity
NXY85_RS07580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NXY85_RS07585	COG0768	penicillin binding
NXY85_RS07590	COG0477	Major facilitator Superfamily
NXY85_RS07595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NXY85_RS07600	COG2839	Protein conserved in bacteria
NXY85_RS07605	COG5521	maltodextrose utilization protein MalA
NXY85_RS07610	COG1388	LysM domain
NXY85_RS07620	COG4709	membrane
NXY85_RS07625	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NXY85_RS07630	COG0735	belongs to the Fur family
NXY85_RS07635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS07645	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXY85_RS07650	COG0513	Belongs to the DEAD box helicase family
NXY85_RS07660	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXY85_RS07665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXY85_RS07670	COG2384	SAM-dependent methyltransferase
NXY85_RS07675	COG2010	Cytochrome c
NXY85_RS07680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXY85_RS07685	COG0358	DNA primase activity
NXY85_RS07690	COG1671	Belongs to the UPF0178 family
NXY85_RS07695	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NXY85_RS07700	COG0517	IMP dehydrogenase activity
NXY85_RS07705	COG0751	glycine-tRNA ligase activity
NXY85_RS07710	COG0752	glycyl-tRNA synthetase alpha subunit
NXY85_RS07715	COG1381	Involved in DNA repair and RecF pathway recombination
NXY85_RS07725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXY85_RS07730	COG0295	cytidine deaminase activity
NXY85_RS07735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NXY85_RS07740	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXY85_RS07745	COG1480	7TM receptor with intracellular HD hydrolase
NXY85_RS07750	COG1702	phosphate starvation-inducible protein PhoH
NXY85_RS07755	COG0561	phosphatase activity
NXY85_RS07770	COG4864	UPF0365 protein
NXY85_RS07775	COG1030	water channel activity
NXY85_RS07780	COG1610	YqeY-like protein
NXY85_RS07790	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXY85_RS07795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXY85_RS07800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NXY85_RS07820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXY85_RS07825	COG1420	regulation of RNA biosynthetic process
NXY85_RS07830	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXY85_RS07835	COG0481	GTPase activity
NXY85_RS07845	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS07860	COG1466	dna polymerase III delta subunit
NXY85_RS07875	COG2333	competence protein COMEC
NXY85_RS07875	COG0658	competence protein
NXY85_RS07880	COG2131	deaminase
NXY85_RS07885	COG1555	photosystem II stabilization
NXY85_RS07885	COG1596	polysaccharide export
NXY85_RS07890	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXY85_RS07895	COG2226	methyltransferase
NXY85_RS07900	COG0799	negative regulation of ribosome biogenesis
NXY85_RS07905	COG1713	HD superfamily hydrolase involved in NAD metabolism
NXY85_RS07910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXY85_RS07915	COG1534	Rna-binding protein
NXY85_RS07920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXY85_RS07925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NXY85_RS07930	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NXY85_RS07945	COG2755	lipolytic protein G-D-S-L family
NXY85_RS07960	COG0398	Pfam SNARE associated Golgi protein
NXY85_RS07970	COG1309	transcriptional regulator
NXY85_RS07975	COG2814	Major facilitator Superfamily
NXY85_RS07985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXY85_RS08005	COG0577	efflux transmembrane transporter activity
NXY85_RS08010	COG3850	Histidine kinase
NXY85_RS08010	COG5002	protein histidine kinase activity
NXY85_RS08015	COG0745	RESPONSE REGULATOR receiver
NXY85_RS08020	COG0730	response to heat
NXY85_RS08025	COG0425	Belongs to the sulfur carrier protein TusA family
NXY85_RS08040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NXY85_RS08040	COG0425	Belongs to the sulfur carrier protein TusA family
NXY85_RS08055	COG1937	Protein conserved in bacteria
NXY85_RS08065	COG0662	Cupin 2, conserved barrel domain protein
NXY85_RS08080	COG2085	NADP oxidoreductase coenzyme F420-dependent
NXY85_RS08085	COG1733	regulation of RNA biosynthetic process
NXY85_RS08110	COG2124	cytochrome p450
NXY85_RS08115	COG1309	transcriptional regulator
NXY85_RS08120	COG2732	(Barnase) inhibitor
NXY85_RS08160	COG1725	Transcriptional regulator
NXY85_RS08175	COG0583	DNA-binding transcription factor activity
NXY85_RS08185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXY85_RS08205	COG3443	Belongs to the bacterial solute-binding protein 9 family
NXY85_RS08220	COG0583	DNA-binding transcription factor activity
NXY85_RS08225	COG2814	Major facilitator Superfamily
NXY85_RS08230	COG2176	DNA-directed DNA polymerase activity
NXY85_RS08235	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NXY85_RS08235	COG2124	cytochrome p450
NXY85_RS08240	COG1309	transcriptional regulator
NXY85_RS08245	COG2226	methyltransferase
NXY85_RS08265	COG2116	formate transmembrane transporter activity
NXY85_RS08270	COG5609	conserved protein (DUF2294)
NXY85_RS08275	COG3383	formate dehydrogenase (NAD+) activity
NXY85_RS08280	COG2427	Protein of unknown function (DUF1641)
NXY85_RS08290	COG0626	cystathionine gamma-synthase activity
NXY85_RS08295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXY85_RS08300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXY85_RS08305	COG2226	methyltransferase
NXY85_RS08320	COG0768	penicillin binding
NXY85_RS08325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXY85_RS08355	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS08360	COG4824	toxin secretion phage lysis holin
NXY85_RS08380	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS08385	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXY85_RS08505	COG0582	viral genome integration into host DNA
NXY85_RS08640	COG4974	Belongs to the 'phage' integrase family
NXY85_RS08665	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS08670	COG4824	toxin secretion phage lysis holin
NXY85_RS08690	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS08815	COG0582	viral genome integration into host DNA
NXY85_RS08950	COG4974	Belongs to the 'phage' integrase family
NXY85_RS08955	COG0572	uridine kinase
NXY85_RS08960	COG0826	peptidase U32
NXY85_RS08965	COG0826	peptidase U32
NXY85_RS08970	COG4122	O-methyltransferase activity
NXY85_RS08975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXY85_RS08980	COG3906	Belongs to the UPF0473 family
NXY85_RS08985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXY85_RS08990	COG4472	Bacterial protein of unknown function (DUF965)
NXY85_RS08995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXY85_RS09000	COG0628	permease
NXY85_RS09005	COG1126	abc transporter atp-binding protein
NXY85_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY85_RS09015	COG0765	amino acid transport
NXY85_RS09020	COG0765	amino acid transport
NXY85_RS09035	COG3881	PFAM PRC-barrel domain
NXY85_RS09040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXY85_RS09045	COG0457	Tetratricopeptide repeat
NXY85_RS09055	COG1104	cysteine desulfurase activity
NXY85_RS09060	COG1959	2 iron, 2 sulfur cluster binding
NXY85_RS09065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXY85_RS09070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXY85_RS09080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXY85_RS09095	COG4991	sh3 domain protein
NXY85_RS09095	COG3103	Sh3 type 3 domain protein
NXY85_RS09095	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS09100	COG1490	D-aminoacyl-tRNA deacylase activity
NXY85_RS09105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXY85_RS09115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NXY85_RS09115	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NXY85_RS09120	COG5416	Lipopolysaccharide assembly protein A domain
NXY85_RS09125	COG0490	domain, Protein
NXY85_RS09130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXY85_RS09130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXY85_RS09140	COG2244	polysaccharide biosynthetic process
NXY85_RS09145	COG2323	membrane
NXY85_RS09155	COG1862	Preprotein translocase
NXY85_RS09165	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXY85_RS09175	COG2255	four-way junction helicase activity
NXY85_RS09180	COG0632	four-way junction helicase activity
NXY85_RS09190	COG2814	Major facilitator Superfamily
NXY85_RS09195	COG2112	serine threonine protein kinase
NXY85_RS09215	COG0217	transcriptional regulatory protein
NXY85_RS09235	COG3394	polysaccharide catabolic process
NXY85_RS09240	COG2188	Transcriptional regulator
NXY85_RS09245	COG1486	melibiose metabolic process
NXY85_RS09250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NXY85_RS09255	COG1447	Phosphotransferase system cellobiose-specific component IIA
NXY85_RS09260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NXY85_RS09275	COG1388	LysM domain
NXY85_RS09280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXY85_RS09285	COG0157	Belongs to the NadC ModD family
NXY85_RS09290	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NXY85_RS09295	COG1104	cysteine desulfurase activity
NXY85_RS09300	COG1827	regulation of RNA biosynthetic process
NXY85_RS09305	COG0077	Prephenate dehydratase
NXY85_RS09310	COG4492	Belongs to the UPF0735 family
NXY85_RS09315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXY85_RS09320	COG3290	protein histidine kinase activity
NXY85_RS09325	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXY85_RS09330	COG2868	ribosomal protein
NXY85_RS09335	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXY85_RS09340	COG1994	Peptidase M50
NXY85_RS09345	COG0739	heme binding
NXY85_RS09350	COG2894	cell division
NXY85_RS09355	COG0850	regulation of cytokinetic process
NXY85_RS09360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NXY85_RS09370	COG1077	Cell shape determining protein MreB Mrl
NXY85_RS09405	COG5632	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS09405	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS09405	COG1388	LysM domain
NXY85_RS09410	COG4824	toxin secretion phage lysis holin
NXY85_RS09430	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS09435	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXY85_RS09445	COG5412	phage tail tape measure protein
NXY85_RS09445	COG3953	SLT domain
NXY85_RS09550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY85_RS09550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY85_RS09595	COG1396	sequence-specific DNA binding
NXY85_RS09615	COG0424	maF-like protein
NXY85_RS09625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NXY85_RS09630	COG0285	dihydrofolate synthase activity
NXY85_RS09635	COG0525	valine-tRNA ligase activity
NXY85_RS09645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NXY85_RS09650	COG1388	LysM domain
NXY85_RS09655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NXY85_RS09660	COG0113	porphobilinogen synthase activity
NXY85_RS09665	COG1587	Uroporphyrinogen-III synthase
NXY85_RS09675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXY85_RS09680	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NXY85_RS09690	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXY85_RS09695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXY85_RS09700	COG1067	ATP-dependent peptidase activity
NXY85_RS09700	COG0470	DNA polymerase III
NXY85_RS09710	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXY85_RS09715	COG0457	Tetratricopeptide repeat
NXY85_RS09715	COG1477	protein flavinylation
NXY85_RS09720	COG0066	3-isopropylmalate dehydratase activity
NXY85_RS09725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXY85_RS09730	COG0473	3-isopropylmalate dehydrogenase activity
NXY85_RS09735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXY85_RS09740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXY85_RS09745	COG0440	acetolactate synthase activity
NXY85_RS09750	COG0028	Belongs to the TPP enzyme family
NXY85_RS09755	COG0454	-acetyltransferase
NXY85_RS09760	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NXY85_RS09780	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NXY85_RS09815	COG0622	Phosphoesterase
NXY85_RS09820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXY85_RS09825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NXY85_RS09830	COG5401	PFAM Sporulation and spore germination
NXY85_RS09835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXY85_RS09840	COG1846	Transcriptional regulator
NXY85_RS09845	COG2197	response regulator
NXY85_RS09850	COG0824	Thioesterase
NXY85_RS09855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXY85_RS09860	COG1053	succinate dehydrogenase
NXY85_RS09865	COG2009	succinate dehydrogenase
NXY85_RS09870	COG1719	4-vinyl reductase, 4VR
NXY85_RS09875	COG0527	aspartate kinase activity
NXY85_RS09880	COG0322	excinuclease ABC activity
NXY85_RS09885	COG3118	belongs to the thioredoxin family
NXY85_RS09890	COG3534	alpha-L-arabinofuranosidase
NXY85_RS09895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXY85_RS09900	COG2086	electron transfer activity
NXY85_RS09905	COG1024	Enoyl-CoA hydratase
NXY85_RS09910	COG1309	transcriptional regulator
NXY85_RS09915	COG0318	PFAM AMP-dependent synthetase and ligase
NXY85_RS09920	COG3766	membrane
NXY85_RS09925	COG1193	negative regulation of DNA recombination
NXY85_RS09930	COG1796	DNA polymerase
NXY85_RS09930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NXY85_RS09935	COG1286	toxin biosynthetic process
NXY85_RS09950	COG0072	phenylalanine-tRNA ligase activity
NXY85_RS09950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY85_RS09955	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXY85_RS09960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXY85_RS09970	COG3835	regulator
NXY85_RS09975	COG0277	FAD linked oxidase domain protein
NXY85_RS09980	COG0247	lactate metabolic process
NXY85_RS09985	COG0346	lactoylglutathione lyase activity
NXY85_RS09990	COG1966	Carbon starvation protein
NXY85_RS09995	COG3534	alpha-L-arabinofuranosidase
NXY85_RS10000	COG0395	ABC-type sugar transport system, permease component
NXY85_RS10005	COG1175	transmembrane transport
NXY85_RS10010	COG1653	transport
NXY85_RS10015	COG0371	Dehydrogenase
NXY85_RS10020	COG0647	UMP catabolic process
NXY85_RS10025	COG0235	Class ii aldolase
NXY85_RS10030	COG1069	ribulokinase activity
NXY85_RS10035	COG2160	L-arabinose isomerase activity
NXY85_RS10060	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY85_RS10065	COG1363	Peptidase, m42
NXY85_RS10075	COG3326	Membrane
NXY85_RS10080	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXY85_RS10085	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXY85_RS10090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXY85_RS10105	COG1346	cytolysis
NXY85_RS10115	COG3279	Response regulator of the LytR AlgR family
NXY85_RS10120	COG3275	phosphorelay sensor kinase activity
NXY85_RS10125	COG1011	Hydrolase
NXY85_RS10130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXY85_RS10140	COG0398	Pfam SNARE associated Golgi protein
NXY85_RS10145	COG1484	DNA-dependent DNA replication
NXY85_RS10150	COG3611	Membrane attachment protein
NXY85_RS10155	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXY85_RS10160	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NXY85_RS10165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NXY85_RS10170	COG1733	regulation of RNA biosynthetic process
NXY85_RS10175	COG2814	Major facilitator Superfamily
NXY85_RS10180	COG0656	L-ascorbic acid biosynthetic process
NXY85_RS10185	COG0237	dephospho-CoA kinase activity
NXY85_RS10190	COG1971	Probably functions as a manganese efflux pump
NXY85_RS10195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NXY85_RS10200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY85_RS10200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY85_RS10205	COG5002	protein histidine kinase activity
NXY85_RS10210	COG0745	RESPONSE REGULATOR receiver
NXY85_RS10220	COG0538	isocitrate dehydrogenase activity
NXY85_RS10225	COG0372	Belongs to the citrate synthase family
NXY85_RS10230	COG2707	UPF0756 membrane protein
NXY85_RS10235	COG0628	permease
NXY85_RS10240	COG3030	protein affecting phage T7 exclusion by the F plasmid
NXY85_RS10245	COG0469	pyruvate kinase activity
NXY85_RS10255	COG0825	malonyl-CoA metabolic process
NXY85_RS10260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NXY85_RS10265	COG0281	malic enzyme
NXY85_RS10270	COG0587	DNA-directed DNA polymerase activity
NXY85_RS10290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXY85_RS10300	COG4109	DRTGG domain
NXY85_RS10305	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NXY85_RS10310	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS10320	COG0165	Argininosuccinate lyase
NXY85_RS10325	COG0137	argininosuccinate synthase activity
NXY85_RS10330	COG0521	Mo-molybdopterin cofactor biosynthetic process
NXY85_RS10340	COG0827	DNA restriction-modification system
NXY85_RS10345	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXY85_RS10350	COG3874	Sporulation protein YtfJ
NXY85_RS10360	COG1714	RDD family
NXY85_RS10365	COG0616	signal peptide processing
NXY85_RS10370	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXY85_RS10375	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NXY85_RS10380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXY85_RS10390	COG0301	tRNA thio-modification
NXY85_RS10395	COG1104	cysteine desulfurase activity
NXY85_RS10400	COG1114	Component of the transport system for branched-chain amino acids
NXY85_RS10410	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NXY85_RS10415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NXY85_RS10420	COG1309	transcriptional regulator
NXY85_RS10425	COG1956	GAF domain-containing protein
NXY85_RS10430	COG2203	Gaf domain
NXY85_RS10430	COG2199	diguanylate cyclase activity
NXY85_RS10455	COG2323	membrane
NXY85_RS10460	COG0697	spore germination
NXY85_RS10465	COG0583	DNA-binding transcription factor activity
NXY85_RS10475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXY85_RS10480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXY85_RS10485	COG0454	-acetyltransferase
NXY85_RS10490	COG0517	IMP dehydrogenase activity
NXY85_RS10495	COG0123	including yeast histone deacetylase and acetoin utilization protein
NXY85_RS10500	COG1360	Flagellar Motor Protein
NXY85_RS10505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NXY85_RS10510	COG1609	Transcriptional regulator
NXY85_RS10515	COG1605	Chorismate mutase
NXY85_RS10515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXY85_RS10520	COG3118	belongs to the thioredoxin family
NXY85_RS10525	COG4980	gas vesicle protein
NXY85_RS10530	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NXY85_RS10540	COG1674	ftsk spoiiie
NXY85_RS10545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY85_RS10550	COG4848	Belongs to the UPF0354 family
NXY85_RS10555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS10565	COG1363	Peptidase, m42
NXY85_RS10570	COG5584	Small secreted protein
NXY85_RS10575	COG0281	malic enzyme
NXY85_RS10580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY85_RS10585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXY85_RS10595	COG0510	thiamine kinase activity
NXY85_RS10600	COG1523	belongs to the glycosyl hydrolase 13 family
NXY85_RS10605	COG1597	lipid kinase activity
NXY85_RS10615	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NXY85_RS10620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXY85_RS10625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXY85_RS10630	COG2252	PERMEase
NXY85_RS10635	COG1349	DNA-binding transcription factor activity
NXY85_RS10640	COG1187	pseudouridine synthase activity
NXY85_RS10645	COG2244	polysaccharide biosynthetic process
NXY85_RS10650	COG2081	HI0933 family
NXY85_RS10655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NXY85_RS10665	COG5578	integral membrane protein
NXY85_RS10670	COG0673	inositol 2-dehydrogenase activity
NXY85_RS10675	COG1653	transport
NXY85_RS10680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXY85_RS10685	COG4209	transmembrane transport
NXY85_RS10690	COG2207	Transcriptional regulator
NXY85_RS10695	COG1653	transport
NXY85_RS10700	COG0395	ABC-type sugar transport system, permease component
NXY85_RS10705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY85_RS10710	COG2124	cytochrome p450
NXY85_RS10715	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXY85_RS10725	COG0156	8-amino-7-oxononanoate synthase activity
NXY85_RS10730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXY85_RS10735	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NXY85_RS10740	COG1073	alpha beta
NXY85_RS10745	COG1653	transport
NXY85_RS10750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NXY85_RS10755	COG0495	leucyl-tRNA aminoacylation
NXY85_RS10765	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS10765	COG2202	Pas domain
NXY85_RS10770	COG2814	Major facilitator Superfamily
NXY85_RS10775	COG2433	Pfam Transposase IS66
NXY85_RS10780	COG0577	efflux transmembrane transporter activity
NXY85_RS10785	COG1136	(ABC) transporter
NXY85_RS10790	COG2205	protein histidine kinase activity
NXY85_RS10795	COG0745	RESPONSE REGULATOR receiver
NXY85_RS10800	COG0577	efflux transmembrane transporter activity
NXY85_RS10805	COG1136	(ABC) transporter
NXY85_RS10815	COG1131	(ABC) transporter
NXY85_RS10820	COG1725	Transcriptional regulator
NXY85_RS10835	COG1242	4 iron, 4 sulfur cluster binding
NXY85_RS10840	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NXY85_RS10850	COG2267	carboxylic ester hydrolase activity
NXY85_RS10855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXY85_RS10860	COG1113	amino acid transport
NXY85_RS10865	COG0367	asparagine synthase
NXY85_RS10875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXY85_RS10885	COG1506	peptidase
NXY85_RS10890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NXY85_RS10895	COG1116	anion transmembrane transporter activity
NXY85_RS10900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NXY85_RS10905	COG0494	nUDIX hydrolase
NXY85_RS10915	COG4824	toxin secretion phage lysis holin
NXY85_RS10920	COG0783	Belongs to the Dps family
NXY85_RS10940	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXY85_RS10945	COG0288	reversible hydration of carbon dioxide
NXY85_RS10950	COG0523	cobalamin synthesis protein
NXY85_RS10960	COG1271	oxidase subunit
NXY85_RS10965	COG1294	oxidase, subunit
NXY85_RS10975	COG4305	rare lipoprotein A
NXY85_RS10985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXY85_RS10990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXY85_RS10990	COG1321	iron dependent repressor
NXY85_RS10995	COG1121	(ABC) transporter
NXY85_RS11000	COG0803	Belongs to the bacterial solute-binding protein 9 family
NXY85_RS11005	COG4948	Mandelate Racemase Muconate Lactonizing
NXY85_RS11010	COG0318	PFAM AMP-dependent synthetase and ligase
NXY85_RS11015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXY85_RS11020	COG0596	Alpha beta hydrolase
NXY85_RS11025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXY85_RS11030	COG1169	isochorismate synthase
NXY85_RS11035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NXY85_RS11040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXY85_RS11045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY85_RS11050	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS11060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NXY85_RS11065	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS11070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NXY85_RS11075	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NXY85_RS11080	COG0058	SHG alpha-glucan phosphorylase activity
NXY85_RS11085	COG0297	glycogen (starch) synthase activity
NXY85_RS11090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NXY85_RS11095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NXY85_RS11100	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXY85_RS11225	COG3859	Proton-coupled thiamine transporter YuaJ
NXY85_RS11230	COG3764	Sortase (surface protein transpeptidase)
NXY85_RS11240	COG2268	Band 7 protein
NXY85_RS11245	COG1585	Membrane protein implicated in regulation of membrane protease activity
NXY85_RS11250	COG2318	DinB family
NXY85_RS11260	COG1454	alcohol dehydrogenase
NXY85_RS11265	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS11270	COG1510	regulation of RNA biosynthetic process
NXY85_RS11280	COG0569	domain protein
NXY85_RS11285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXY85_RS11290	COG4682	membrane
NXY85_RS11295	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXY85_RS11300	COG0477	Major facilitator Superfamily
NXY85_RS11315	COG0628	permease
NXY85_RS11320	COG0673	inositol 2-dehydrogenase activity
NXY85_RS11325	COG0693	protein deglycase activity
NXY85_RS11330	COG4806	L-rhamnose isomerase
NXY85_RS11335	COG3254	rhamnose metabolic process
NXY85_RS11340	COG1070	Carbohydrate kinase
NXY85_RS11345	COG1349	DNA-binding transcription factor activity
NXY85_RS11350	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS11350	COG3347	Dehydrogenase
NXY85_RS11355	COG0840	transmembrane signaling receptor activity
NXY85_RS11360	COG0840	transmembrane signaling receptor activity
NXY85_RS11365	COG0840	transmembrane signaling receptor activity
NXY85_RS11370	COG0840	transmembrane signaling receptor activity
NXY85_RS11385	COG2070	2-Nitropropane dioxygenase
NXY85_RS11390	COG0432	Pfam Uncharacterised protein family UPF0047
NXY85_RS11395	COG0366	Alpha amylase catalytic
NXY85_RS11400	COG1253	flavin adenine dinucleotide binding
NXY85_RS11405	COG2738	Putative neutral zinc metallopeptidase
NXY85_RS11420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXY85_RS11435	COG0166	Belongs to the GPI family
NXY85_RS11440	COG1979	alcohol dehydrogenase
NXY85_RS11445	COG1979	alcohol dehydrogenase
NXY85_RS11450	COG2155	Conserved Protein
NXY85_RS11455	COG1098	S1 RNA binding domain
NXY85_RS11460	COG0436	Aminotransferase
NXY85_RS11465	COG1522	sequence-specific DNA binding
NXY85_RS11470	COG2267	carboxylic ester hydrolase activity
NXY85_RS11480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXY85_RS11485	COG2205	protein histidine kinase activity
NXY85_RS11495	COG5018	Exonuclease
NXY85_RS11500	COG2814	Major facilitator Superfamily
NXY85_RS11505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXY85_RS11510	COG3011	Protein conserved in bacteria
NXY85_RS11520	COG3290	protein histidine kinase activity
NXY85_RS11525	COG4565	transcriptional regulatory protein
NXY85_RS11530	COG1744	ABC transporter substrate-binding protein PnrA-like
NXY85_RS11535	COG3845	ABC transporter
NXY85_RS11540	COG4603	Belongs to the binding-protein-dependent transport system permease family
NXY85_RS11545	COG1079	Belongs to the binding-protein-dependent transport system permease family
NXY85_RS11550	COG3493	citrate carrier protein
NXY85_RS11560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXY85_RS11560	COG2111	Na H antiporter
NXY85_RS11565	COG2111	Na H antiporter
NXY85_RS11570	COG1006	Multisubunit Na H antiporter MnhC subunit
NXY85_RS11575	COG0651	ATP synthesis coupled electron transport
NXY85_RS11580	COG1863	multisubunit Na H antiporter MnhE subunit
NXY85_RS11585	COG2212	antiporter activity
NXY85_RS11590	COG1320	monovalent cation:proton antiporter activity
NXY85_RS11595	COG2050	protein possibly involved in aromatic compounds catabolism
NXY85_RS11600	COG2197	response regulator
NXY85_RS11615	COG0142	geranyltranstransferase activity
NXY85_RS11630	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NXY85_RS11635	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXY85_RS11640	COG1335	isochorismatase
NXY85_RS11645	COG5506	Protein of unknown function (DUF1694)
NXY85_RS11660	COG0628	permease
NXY85_RS11670	COG1418	mRNA catabolic process
NXY85_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS11685	COG1511	domain protein
NXY85_RS11690	COG0433	COG0433 Predicted ATPase
NXY85_RS11690	COG1674	ftsk spoiiie
NXY85_RS11695	COG4499	WXG100 protein secretion system (Wss), protein YukC
NXY85_RS11700	COG5417	Belongs to the EsaB family
NXY85_RS11705	COG4842	Belongs to the WXG100 family
NXY85_RS11710	COG2508	Transcriptional regulator
NXY85_RS11710	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NXY85_RS11715	COG0686	Belongs to the AlaDH PNT family
NXY85_RS11720	COG5634	Uncharacterized conserved protein (DUF2278)
NXY85_RS11725	COG3251	PFAM MbtH domain protein
NXY85_RS11730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS11735	COG1535	isochorismatase
NXY85_RS11735	COG3433	isochorismatase activity
NXY85_RS11740	COG1021	2,3-dihydroxybenzoate-AMP ligase
NXY85_RS11745	COG1169	isochorismate synthase
NXY85_RS11750	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS11755	COG2819	hydrolase of the alpha beta superfamily
NXY85_RS11770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NXY85_RS11775	COG1268	BioY protein
NXY85_RS11780	COG2056	Na+-H+ antiporter family
NXY85_RS11785	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NXY85_RS11790	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NXY85_RS11795	COG3584	3D domain protein
NXY85_RS11810	COG1252	NADH dehydrogenase
NXY85_RS11825	COG0516	GMP reductase activity
NXY85_RS11855	COG0316	Belongs to the HesB IscA family
NXY85_RS11860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXY85_RS11865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NXY85_RS11870	COG4844	belongs to the
NXY85_RS11875	COG1252	NADH dehydrogenase
NXY85_RS11880	COG3479	Phenolic acid decarboxylase
NXY85_RS11885	COG4837	Protein of unknown function (DUF1462)
NXY85_RS11890	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NXY85_RS11895	COG4946	Tricorn protease homolog
NXY85_RS11895	COG1506	peptidase
NXY85_RS11895	COG0823	Involved in the tonB-independent uptake of proteins
NXY85_RS11900	COG0083	homoserine kinase activity
NXY85_RS11905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NXY85_RS11910	COG0460	homoserine dehydrogenase
NXY85_RS11915	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NXY85_RS11920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXY85_RS11925	COG0647	UMP catabolic process
NXY85_RS11930	COG2445	Protein of unknown function DUF86
NXY85_RS11935	COG4470	Protein conserved in bacteria
NXY85_RS11950	COG0739	heme binding
NXY85_RS11960	COG3377	Domain of unknown function (DUF1805)
NXY85_RS11965	COG0737	Belongs to the 5'-nucleotidase family
NXY85_RS11970	COG0730	response to heat
NXY85_RS11975	COG1801	Protein of unknown function DUF72
NXY85_RS11990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NXY85_RS11995	COG2508	Transcriptional regulator
NXY85_RS12000	COG2233	PERMEase
NXY85_RS12005	COG1595	DNA-templated transcription, initiation
NXY85_RS12085	COG1131	(ABC) transporter
NXY85_RS12100	COG2814	Major facilitator Superfamily
NXY85_RS12115	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NXY85_RS12120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXY85_RS12125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXY85_RS12130	COG2356	endonuclease I
NXY85_RS12140	COG3842	ATPase activity
NXY85_RS12145	COG2188	Transcriptional regulator
NXY85_RS12150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY85_RS12155	COG0395	ABC-type sugar transport system, permease component
NXY85_RS12160	COG1175	transmembrane transport
NXY85_RS12165	COG1653	transport
NXY85_RS12170	COG2222	sugar isomerase
NXY85_RS12175	COG0322	excinuclease ABC activity
NXY85_RS12180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXY85_RS12185	COG0719	Fe-S assembly protein
NXY85_RS12190	COG0822	iron-sulfur transferase activity
NXY85_RS12195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXY85_RS12200	COG0719	Fe-S assembly protein
NXY85_RS12205	COG0396	ATPase activity
NXY85_RS12215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NXY85_RS12220	COG1464	Belongs to the NlpA lipoprotein family
NXY85_RS12225	COG2011	ABC-type metal ion transport system permease component
NXY85_RS12230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NXY85_RS12240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS12245	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NXY85_RS12255	COG0509	glycine decarboxylation via glycine cleavage system
NXY85_RS12260	COG1393	Belongs to the ArsC family
NXY85_RS12265	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS12270	COG0183	Belongs to the thiolase family
NXY85_RS12275	COG1250	3-hydroxyacyl-CoA dehydrogenase
NXY85_RS12275	COG1024	Enoyl-CoA hydratase
NXY85_RS12295	COG5577	PFAM Coat F domain
NXY85_RS12300	COG1846	Transcriptional regulator
NXY85_RS12305	COG0477	Major facilitator Superfamily
NXY85_RS12315	COG1120	ATPase activity
NXY85_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS12335	COG0783	Belongs to the Dps family
NXY85_RS12340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY85_RS12345	COG0745	RESPONSE REGULATOR receiver
NXY85_RS12350	COG2770	Histidine kinase
NXY85_RS12350	COG2205	protein histidine kinase activity
NXY85_RS12360	COG1309	transcriptional regulator
NXY85_RS12365	COG0114	fumarate hydratase activity
NXY85_RS12375	COG0697	spore germination
NXY85_RS12380	COG0814	amino acid
NXY85_RS12390	COG2197	response regulator
NXY85_RS12400	COG4758	membrane
NXY85_RS12405	COG3595	metallopeptidase activity
NXY85_RS12410	COG1842	Phage shock protein A
NXY85_RS12415	COG4758	membrane
NXY85_RS12420	COG2814	Major facilitator Superfamily
NXY85_RS12425	COG2096	Adenosyltransferase
NXY85_RS12430	COG1120	ATPase activity
NXY85_RS12435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS12440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NXY85_RS12445	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS12450	COG3386	PFAM SMP-30 Gluconolaconase
NXY85_RS12455	COG2205	protein histidine kinase activity
NXY85_RS12460	COG0745	RESPONSE REGULATOR receiver
NXY85_RS12470	COG1191	sigma factor activity
NXY85_RS12480	COG2140	Oxalate decarboxylase
NXY85_RS12490	COG0577	efflux transmembrane transporter activity
NXY85_RS12495	COG1136	(ABC) transporter
NXY85_RS12500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY85_RS12505	COG1120	ATPase activity
NXY85_RS12510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS12515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS12520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NXY85_RS12530	COG0531	amino acid
NXY85_RS12545	COG1988	membrane-bound metal-dependent
NXY85_RS12550	COG1368	sulfuric ester hydrolase activity
NXY85_RS12555	COG1910	domain protein
NXY85_RS12560	COG0725	ABC transporter, periplasmic molybdate-binding protein
NXY85_RS12565	COG4149	molybdate abc transporter
NXY85_RS12575	COG0656	L-ascorbic acid biosynthetic process
NXY85_RS12595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NXY85_RS12600	COG3973	AAA domain
NXY85_RS12605	COG2860	membrane
NXY85_RS12615	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NXY85_RS12620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NXY85_RS12625	COG2217	Heavy metal translocating P-type atpase
NXY85_RS12630	COG2217	Heavy metal translocating P-type atpase
NXY85_RS12635	COG2608	mercury ion transmembrane transporter activity
NXY85_RS12640	COG1937	Protein conserved in bacteria
NXY85_RS12645	COG0673	inositol 2-dehydrogenase activity
NXY85_RS12655	COG1289	transmembrane transporter activity
NXY85_RS12665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXY85_RS12670	COG0557	exoribonuclease II activity
NXY85_RS12675	COG1647	Serine aminopeptidase, S33
NXY85_RS12680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXY85_RS12685	COG1476	TRANSCRIPTIONal
NXY85_RS12690	COG1396	sequence-specific DNA binding
NXY85_RS12695	COG1396	sequence-specific DNA binding
NXY85_RS12700	COG1733	regulation of RNA biosynthetic process
NXY85_RS12705	COG0840	transmembrane signaling receptor activity
NXY85_RS12710	COG1174	glycine betaine transport
NXY85_RS12715	COG1732	Glycine betaine
NXY85_RS12720	COG1174	glycine betaine transport
NXY85_RS12725	COG0517	IMP dehydrogenase activity
NXY85_RS12725	COG1125	glycine betaine transport
NXY85_RS12730	COG1510	regulation of RNA biosynthetic process
NXY85_RS12735	COG1174	glycine betaine transport
NXY85_RS12740	COG1732	Glycine betaine
NXY85_RS12745	COG1174	glycine betaine transport
NXY85_RS12750	COG1125	glycine betaine transport
NXY85_RS12750	COG0517	IMP dehydrogenase activity
NXY85_RS12755	COG1510	regulation of RNA biosynthetic process
NXY85_RS12765	COG3064	Membrane
NXY85_RS12770	COG4640	response to antibiotic
NXY85_RS12775	COG0456	acetyltransferase
NXY85_RS12780	COG1136	(ABC) transporter
NXY85_RS12785	COG0577	efflux transmembrane transporter activity
NXY85_RS12785	COG0577	efflux transmembrane transporter activity
NXY85_RS12795	COG1131	(ABC) transporter
NXY85_RS12835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXY85_RS12840	COG0149	triose-phosphate isomerase activity
NXY85_RS12845	COG0126	phosphoglycerate kinase activity
NXY85_RS12850	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NXY85_RS12855	COG2390	Transcriptional regulator
NXY85_RS12860	COG2814	Major facilitator Superfamily
NXY85_RS12865	COG1609	Transcriptional regulator
NXY85_RS12870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NXY85_RS12875	COG0583	DNA-binding transcription factor activity
NXY85_RS12880	COG0697	spore germination
NXY85_RS12885	COG1113	amino acid transport
NXY85_RS12890	COG3858	chitin binding
NXY85_RS12895	COG1556	Lactate utilization protein
NXY85_RS12900	COG1139	Iron-sulfur cluster binding protein
NXY85_RS12905	COG0247	lactate metabolic process
NXY85_RS12915	COG2186	Transcriptional regulator
NXY85_RS12920	COG1620	l-lactate permease
NXY85_RS12925	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NXY85_RS12935	COG5039	Polysaccharide pyruvyl transferase
NXY85_RS12940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXY85_RS12945	COG0110	maltose O-acetyltransferase activity
NXY85_RS12950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXY85_RS12955	COG2244	polysaccharide biosynthetic process
NXY85_RS12960	COG1216	Glycosyl transferase, family 2
NXY85_RS12965	COG5039	Polysaccharide pyruvyl transferase
NXY85_RS12970	COG1216	Glycosyl transferase, family 2
NXY85_RS12980	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS12985	COG1215	transferase activity, transferring glycosyl groups
NXY85_RS12990	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS12995	COG1086	Polysaccharide biosynthesis protein
NXY85_RS13000	COG0489	protein tyrosine kinase activity
NXY85_RS13005	COG3944	biosynthesis protein
NXY85_RS13010	COG1396	sequence-specific DNA binding
NXY85_RS13015	COG2272	Belongs to the type-B carboxylesterase lipase family
NXY85_RS13030	COG1621	beta-fructofuranosidase activity
NXY85_RS13035	COG1621	beta-fructofuranosidase activity
NXY85_RS13040	COG0531	amino acid
NXY85_RS13045	COG1309	transcriptional regulator
NXY85_RS13050	COG2076	Multidrug Resistance protein
NXY85_RS13055	COG2076	Multidrug Resistance protein
NXY85_RS13060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS13085	COG1611	Belongs to the LOG family
NXY85_RS13090	COG1694	Mazg nucleotide pyrophosphohydrolase
NXY85_RS13095	COG0659	secondary active sulfate transmembrane transporter activity
NXY85_RS13100	COG0288	reversible hydration of carbon dioxide
NXY85_RS13105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXY85_RS13110	COG0577	efflux transmembrane transporter activity
NXY85_RS13115	COG1136	(ABC) transporter
NXY85_RS13120	COG5002	protein histidine kinase activity
NXY85_RS13125	COG0745	RESPONSE REGULATOR receiver
NXY85_RS13130	COG4290	ribonuclease
NXY85_RS13135	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NXY85_RS13140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS13150	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NXY85_RS13155	COG1660	Displays ATPase and GTPase activities
NXY85_RS13160	COG1051	belongs to the nudix hydrolase family
NXY85_RS13165	COG0492	ferredoxin-NADP+ reductase activity
NXY85_RS13170	COG0791	NLP P60 protein
NXY85_RS13170	COG3883	PFAM NLP P60 protein
NXY85_RS13175	COG0457	Tetratricopeptide repeat
NXY85_RS13180	COG1132	(ABC) transporter
NXY85_RS13200	COG0140	phosphoribosyl-ATP diphosphatase activity
NXY85_RS13200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXY85_RS13205	COG0107	imidazoleglycerol-phosphate synthase activity
NXY85_RS13210	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXY85_RS13220	COG0131	Imidazoleglycerol-phosphate dehydratase
NXY85_RS13225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXY85_RS13230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXY85_RS13235	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NXY85_RS13240	COG4990	cell redox homeostasis
NXY85_RS13245	COG5297	Belongs to the glycosyl hydrolase family 6
NXY85_RS13250	COG0110	maltose O-acetyltransferase activity
NXY85_RS13255	COG0546	phosphoglycolate phosphatase activity
NXY85_RS13260	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXY85_RS13265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXY85_RS13270	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NXY85_RS13275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXY85_RS13285	COG2188	Transcriptional regulator
NXY85_RS13290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NXY85_RS13295	COG1950	PFAM Membrane protein of
NXY85_RS13300	COG1983	PspC domain protein
NXY85_RS13305	COG3595	metallopeptidase activity
NXY85_RS13320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NXY85_RS13330	COG4897	Protein conserved in bacteria
NXY85_RS13335	COG3848	Pyruvate phosphate dikinase
NXY85_RS13335	COG0574	Belongs to the PEP-utilizing enzyme family
NXY85_RS13340	COG1309	transcriptional regulator
NXY85_RS13345	COG2814	Major facilitator Superfamily
NXY85_RS13355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY85_RS13365	COG0793	Belongs to the peptidase S41A family
NXY85_RS13365	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS13370	COG2177	Part of the ABC transporter FtsEX involved in
NXY85_RS13375	COG2884	Cell division ATP-binding protein ftsE
NXY85_RS13380	COG2010	Cytochrome c
NXY85_RS13385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS13395	COG0653	protein targeting
NXY85_RS13400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NXY85_RS13415	COG1516	flagellar protein fliS
NXY85_RS13420	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NXY85_RS13425	COG1334	flagellar protein FlaG
NXY85_RS13430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NXY85_RS13435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NXY85_RS13440	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NXY85_RS13450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NXY85_RS13455	COG1256	bacterial-type flagellum assembly
NXY85_RS13455	COG4786	Flagellar basal body rod
NXY85_RS13460	COG3418	PFAM FlgN family protein
NXY85_RS13465	COG2747	anti-sigma28 factor FlgM
NXY85_RS13475	COG1040	competence protein
NXY85_RS13485	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NXY85_RS13490	COG1307	EDD domain protein, DegV family
NXY85_RS13495	COG2197	response regulator
NXY85_RS13500	COG4585	Histidine kinase
NXY85_RS13505	COG1739	Uncharacterized protein family UPF0029
NXY85_RS13510	COG1316	TRANSCRIPTIONal
NXY85_RS13515	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXY85_RS13520	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS13525	COG1215	transferase activity, transferring glycosyl groups
NXY85_RS13530	COG3206	protein involved in exopolysaccharide biosynthesis
NXY85_RS13535	COG3307	-O-antigen
NXY85_RS13540	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXY85_RS13545	COG0297	glycogen (starch) synthase activity
NXY85_RS13545	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS13550	COG2244	polysaccharide biosynthetic process
NXY85_RS13560	COG2247	cell wall binding repeat
NXY85_RS13560	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS13565	COG2247	cell wall binding repeat
NXY85_RS13565	COG2385	sporulation resulting in formation of a cellular spore
NXY85_RS13575	COG1316	TRANSCRIPTIONal
NXY85_RS13580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NXY85_RS13585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NXY85_RS13595	COG1682	transport, permease protein
NXY85_RS13600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXY85_RS13605	COG0438	transferase activity, transferring glycosyl groups
NXY85_RS13610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NXY85_RS13615	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NXY85_RS13620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXY85_RS13625	COG4193	domain, Protein
NXY85_RS13630	COG1482	cell wall glycoprotein biosynthetic process
NXY85_RS13635	COG0697	spore germination
NXY85_RS13640	COG0814	amino acid
NXY85_RS13655	COG2814	Major facilitator Superfamily
NXY85_RS13660	COG1316	TRANSCRIPTIONal
NXY85_RS13665	COG0561	phosphatase activity
NXY85_RS13670	COG0791	NLP P60 protein
NXY85_RS13680	COG2843	Capsule synthesis protein
NXY85_RS13690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXY85_RS13695	COG0697	spore germination
NXY85_RS13700	COG0531	amino acid
NXY85_RS13710	COG1609	Transcriptional regulator
NXY85_RS13715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY85_RS13720	COG1869	D-ribose catabolic process
NXY85_RS13725	COG1129	ABC transporter
NXY85_RS13730	COG1172	Belongs to the binding-protein-dependent transport system permease family
NXY85_RS13735	COG1879	ABC-type sugar transport system periplasmic component
NXY85_RS13740	COG3103	Sh3 type 3 domain protein
NXY85_RS13750	COG2249	NAD(P)H dehydrogenase (quinone) activity
NXY85_RS13755	COG3527	Alpha-acetolactate decarboxylase
NXY85_RS13760	COG0028	Belongs to the TPP enzyme family
NXY85_RS13765	COG0583	DNA-binding transcription factor activity
NXY85_RS13770	COG5337	Spore coat protein CotH
NXY85_RS13780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NXY85_RS13785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS13800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXY85_RS13810	COG0405	Gamma-glutamyltransferase
NXY85_RS13815	COG1522	sequence-specific DNA binding
NXY85_RS13820	COG2059	Chromate
NXY85_RS13825	COG2059	Chromate
NXY85_RS13835	COG0655	NAD(P)H dehydrogenase (quinone) activity
NXY85_RS13840	COG0583	DNA-binding transcription factor activity
NXY85_RS13860	COG5444	nuclease activity
NXY85_RS13880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXY85_RS13890	COG4464	protein tyrosine phosphatase activity
NXY85_RS13895	COG0489	protein tyrosine kinase activity
NXY85_RS13900	COG3944	biosynthesis protein
NXY85_RS13910	COG4715	Zinc finger, swim domain protein
NXY85_RS13915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXY85_RS13920	COG0561	phosphatase activity
NXY85_RS13925	COG1349	DNA-binding transcription factor activity
NXY85_RS13930	COG0629	single-stranded DNA binding
NXY85_RS13945	COG1970	mechanosensitive ion channel activity
NXY85_RS13955	COG0457	Tetratricopeptide repeat
NXY85_RS13960	COG4786	Flagellar basal body rod
NXY85_RS13965	COG4786	Flagellar basal body rod
NXY85_RS13970	COG1077	Cell shape determining protein MreB Mrl
NXY85_RS13975	COG1609	Transcriptional regulator
NXY85_RS13985	COG1846	Transcriptional regulator
NXY85_RS13990	COG2814	Major facilitator Superfamily
NXY85_RS13995	COG1953	Uracil, thiamine, allantoin
NXY85_RS14000	COG0477	Major facilitator Superfamily
NXY85_RS14005	COG1335	isochorismatase
NXY85_RS14015	COG0004	ammonium transporteR
NXY85_RS14020	COG0347	Belongs to the P(II) protein family
NXY85_RS14025	COG0772	Belongs to the SEDS family
NXY85_RS14030	COG0671	phosphoesterase, PA-phosphatase related
NXY85_RS14040	COG0739	heme binding
NXY85_RS14045	COG1247	-acetyltransferase
NXY85_RS14055	COG1086	Polysaccharide biosynthesis protein
NXY85_RS14060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY85_RS14065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXY85_RS14070	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NXY85_RS14085	COG2089	acid synthase
NXY85_RS14095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXY85_RS14100	COG0789	Transcriptional regulator
NXY85_RS14110	COG2910	NAD(P)H-binding
NXY85_RS14115	COG1959	2 iron, 2 sulfur cluster binding
NXY85_RS14120	COG0804	urea catabolic process
NXY85_RS14130	COG0831	urea catabolic process
NXY85_RS14135	COG3237	CsbD-like
NXY85_RS14140	COG1994	Peptidase M50
NXY85_RS14145	COG0457	Tetratricopeptide repeat
NXY85_RS14155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NXY85_RS14165	COG2304	oxidoreductase activity
NXY85_RS14170	COG2304	oxidoreductase activity
NXY85_RS14175	COG2385	sporulation resulting in formation of a cellular spore
NXY85_RS14180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXY85_RS14190	COG4836	Membrane
NXY85_RS14200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXY85_RS14205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXY85_RS14210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXY85_RS14220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXY85_RS14225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXY85_RS14245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXY85_RS14250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXY85_RS14255	COG4475	Protein of unknown function (DUF436)
NXY85_RS14260	COG0698	ribose 5-phosphate isomerase
NXY85_RS14265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXY85_RS14270	COG1971	Probably functions as a manganese efflux pump
NXY85_RS14275	COG0009	L-threonylcarbamoyladenylate synthase
NXY85_RS14280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NXY85_RS14300	COG2890	protein-(glutamine-N5) methyltransferase activity
NXY85_RS14305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXY85_RS14310	COG0346	lactoylglutathione lyase activity
NXY85_RS14315	COG0789	Transcriptional regulator
NXY85_RS14320	COG0679	Auxin Efflux Carrier
NXY85_RS14325	COG0281	malic enzyme
NXY85_RS14335	COG0254	rRNA binding
NXY85_RS14340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NXY85_RS14350	COG1494	fructose-1,6-bisphosphatase
NXY85_RS14355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXY85_RS14365	COG0191	fructose-bisphosphate aldolase activity
NXY85_RS14370	COG2204	response regulator
NXY85_RS14375	COG4821	SIS domain
NXY85_RS14380	COG0504	CTP synthase activity
NXY85_RS14385	COG3343	RNA polymerase activity
NXY85_RS14390	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS14395	COG0247	lactate metabolic process
NXY85_RS14395	COG2181	nitrate reductase activity
NXY85_RS14400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXY85_RS14405	COG4294	response to UV
NXY85_RS14415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NXY85_RS14420	COG1132	(ABC) transporter
NXY85_RS14425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXY85_RS14430	COG2181	nitrate reductase activity
NXY85_RS14435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NXY85_RS14440	COG1140	nitrate reductase beta subunit
NXY85_RS14445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NXY85_RS14450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXY85_RS14460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXY85_RS14465	COG2223	nitrite transmembrane transporter activity
NXY85_RS14470	COG0018	arginyl-trna synthetase
NXY85_RS14475	COG4506	Protein conserved in bacteria
NXY85_RS14495	COG3391	amine dehydrogenase activity
NXY85_RS14505	COG1388	LysM domain
NXY85_RS14510	COG0457	Tetratricopeptide repeat
NXY85_RS14520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXY85_RS14525	COG0010	Belongs to the arginase family
NXY85_RS14530	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NXY85_RS14535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXY85_RS14550	COG1994	Peptidase M50
NXY85_RS14555	COG1942	4-Oxalocrotonate Tautomerase
NXY85_RS14560	COG1846	Transcriptional regulator
NXY85_RS14565	COG0531	amino acid
NXY85_RS14570	COG3465	dGTPase activity
NXY85_RS14575	COG1078	dGTPase activity
NXY85_RS14580	COG4844	belongs to the
NXY85_RS14590	COG0697	spore germination
NXY85_RS14595	COG0095	Lipoate-protein ligase
NXY85_RS14600	COG0583	DNA-binding transcription factor activity
NXY85_RS14610	COG0280	phosphate acetyltransferase
NXY85_RS14615	COG3253	May function as heme-dependent peroxidase
NXY85_RS14620	COG2814	Major facilitator Superfamily
NXY85_RS14625	COG2814	Major facilitator Superfamily
NXY85_RS14635	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NXY85_RS14640	COG1091	dTDP-4-dehydrorhamnose reductase activity
NXY85_RS14645	COG1088	dTDP-glucose 4,6-dehydratase activity
NXY85_RS14650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXY85_RS14655	COG0456	acetyltransferase
NXY85_RS14660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXY85_RS14665	COG0463	Glycosyl transferase, family 2
NXY85_RS14675	COG2363	Small membrane protein
NXY85_RS14680	COG2233	PERMEase
NXY85_RS14690	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS14695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXY85_RS14700	COG1216	Glycosyl transferase, family 2
NXY85_RS14715	COG1695	Transcriptional regulator
NXY85_RS14720	COG0351	phosphomethylpyrimidine kinase
NXY85_RS14730	COG0110	maltose O-acetyltransferase activity
NXY85_RS14735	COG1621	beta-fructofuranosidase activity
NXY85_RS14740	COG1263	PTS System
NXY85_RS14740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS14750	COG3711	transcriptional antiterminator
NXY85_RS14760	COG1404	Belongs to the peptidase S8 family
NXY85_RS14770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NXY85_RS14775	COG0778	Nitroreductase
NXY85_RS14780	COG0772	Belongs to the SEDS family
NXY85_RS14795	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NXY85_RS14805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NXY85_RS14810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NXY85_RS14815	COG2261	transglycosylase associated protein
NXY85_RS14820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NXY85_RS14825	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXY85_RS14830	COG2246	polysaccharide biosynthetic process
NXY85_RS14835	COG1309	transcriptional regulator
NXY85_RS14855	COG3162	membrane
NXY85_RS14860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS14865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NXY85_RS14870	COG0352	thiamine-phosphate diphosphorylase activity
NXY85_RS14875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NXY85_RS14880	COG0583	DNA-binding transcription factor activity
NXY85_RS14890	COG1346	cytolysis
NXY85_RS14895	COG1131	(ABC) transporter
NXY85_RS14910	COG4895	conserved protein (DUF2196)
NXY85_RS14915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXY85_RS14920	COG0346	lactoylglutathione lyase activity
NXY85_RS14925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NXY85_RS14935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS14935	COG1263	PTS System
NXY85_RS14940	COG3711	transcriptional antiterminator
NXY85_RS14945	COG1442	glycosyl transferase family 8
NXY85_RS14950	COG5522	Integral membrane protein (intg_mem_TP0381)
NXY85_RS14955	COG2234	aminopeptidase activity
NXY85_RS14960	COG0457	Tetratricopeptide repeat
NXY85_RS14965	COG1846	Transcriptional regulator
NXY85_RS14970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXY85_RS14975	COG2357	RelA SpoT domain protein
NXY85_RS14980	COG1575	Belongs to the MenA family. Type 1 subfamily
NXY85_RS14990	COG0569	domain protein
NXY85_RS15000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS15005	COG1696	Membrane protein involved in D-alanine export
NXY85_RS15015	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NXY85_RS15020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXY85_RS15025	COG1486	melibiose metabolic process
NXY85_RS15030	COG1447	Phosphotransferase system cellobiose-specific component IIA
NXY85_RS15035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NXY85_RS15040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NXY85_RS15045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS15045	COG3711	transcriptional antiterminator
NXY85_RS15055	COG2094	Belongs to the DNA glycosylase MPG family
NXY85_RS15060	COG0753	catalase activity
NXY85_RS15065	COG2814	Major facilitator Superfamily
NXY85_RS15070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NXY85_RS15075	COG1131	(ABC) transporter
NXY85_RS15095	COG1595	DNA-templated transcription, initiation
NXY85_RS15100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NXY85_RS15105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXY85_RS15110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NXY85_RS15115	COG4988	ABC transporter
NXY85_RS15120	COG1294	oxidase, subunit
NXY85_RS15125	COG1271	oxidase subunit
NXY85_RS15135	COG3493	citrate carrier protein
NXY85_RS15145	COG0726	polysaccharide deacetylase
NXY85_RS15150	COG3842	ATPase activity
NXY85_RS15155	COG2508	Transcriptional regulator
NXY85_RS15160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS15170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXY85_RS15175	COG1881	PFAM PEBP family protein
NXY85_RS15190	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXY85_RS15205	COG4894	glucomannan catabolic process
NXY85_RS15210	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NXY85_RS15215	COG3290	protein histidine kinase activity
NXY85_RS15215	COG3829	transcription factor binding
NXY85_RS15220	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS15225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NXY85_RS15230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NXY85_RS15235	COG2610	gluconate transmembrane transporter activity
NXY85_RS15240	COG0500	methyltransferase
NXY85_RS15245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NXY85_RS15260	COG0693	protein deglycase activity
NXY85_RS15260	COG0753	catalase activity
NXY85_RS15265	COG2851	Citrate transporter
NXY85_RS15275	COG3711	transcriptional antiterminator
NXY85_RS15285	COG2270	Major facilitator Superfamily
NXY85_RS15290	COG0513	Belongs to the DEAD box helicase family
NXY85_RS15295	COG0346	lactoylglutathione lyase activity
NXY85_RS15305	COG2755	lipolytic protein G-D-S-L family
NXY85_RS15305	COG3401	FG-GAP repeat protein
NXY85_RS15340	COG3209	COG3209 Rhs family protein
NXY85_RS15345	COG3866	Pectate lyase
NXY85_RS15350	COG0697	spore germination
NXY85_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS15375	COG0589	response to stress
NXY85_RS15380	COG2723	6-phospho-beta-galactosidase activity
NXY85_RS15385	COG1263	PTS System
NXY85_RS15385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS15385	COG2190	(PTS) system
NXY85_RS15390	COG3977	Valine--pyruvate aminotransferase
NXY85_RS15405	COG1181	Belongs to the D-alanine--D-alanine ligase family
NXY85_RS15420	COG0494	nUDIX hydrolase
NXY85_RS15425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXY85_RS15430	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY85_RS15440	COG2986	histidine ammonia-lyase
NXY85_RS15445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXY85_RS15450	COG1228	amidohydrolase
NXY85_RS15455	COG0010	Belongs to the arginase family
NXY85_RS15460	COG0833	amino acid
NXY85_RS15465	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NXY85_RS15470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NXY85_RS15475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXY85_RS15480	COG2390	Transcriptional regulator
NXY85_RS15490	COG3192	ethanolamine utilization protein
NXY85_RS15495	COG1940	carbohydrate kinase activity
NXY85_RS15500	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NXY85_RS15505	COG0561	phosphatase activity
NXY85_RS15530	COG5294	Protein conserved in bacteria
NXY85_RS15535	COG0577	efflux transmembrane transporter activity
NXY85_RS15540	COG1136	(ABC) transporter
NXY85_RS15545	COG2205	protein histidine kinase activity
NXY85_RS15550	COG0745	RESPONSE REGULATOR receiver
NXY85_RS15560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NXY85_RS15575	COG1082	Xylose isomerase domain protein TIM barrel
NXY85_RS15580	COG0673	inositol 2-dehydrogenase activity
NXY85_RS15585	COG2814	Major facilitator Superfamily
NXY85_RS15590	COG1082	Xylose isomerase domain protein TIM barrel
NXY85_RS15595	COG3962	Belongs to the TPP enzyme family
NXY85_RS15600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY85_RS15615	COG1349	DNA-binding transcription factor activity
NXY85_RS15620	COG0667	Aldo Keto reductase
NXY85_RS15640	COG2814	Major facilitator Superfamily
NXY85_RS15645	COG0326	Molecular chaperone. Has ATPase activity
NXY85_RS15655	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS15660	COG1309	transcriptional regulator
NXY85_RS15665	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS15675	COG1714	RDD family
NXY85_RS15680	COG2311	Membrane
NXY85_RS15685	COG1917	Cupin 2, conserved barrel domain protein
NXY85_RS15690	COG1309	transcriptional regulator
NXY85_RS15720	COG5039	Polysaccharide pyruvyl transferase
NXY85_RS15725	COG1929	Belongs to the glycerate kinase type-1 family
NXY85_RS15730	COG2610	gluconate transmembrane transporter activity
NXY85_RS15735	COG3835	regulator
NXY85_RS15740	COG1802	Transcriptional regulator
NXY85_RS15745	COG1070	Carbohydrate kinase
NXY85_RS15750	COG2610	gluconate transmembrane transporter activity
NXY85_RS15755	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXY85_RS15760	COG0450	alkyl hydroperoxide reductase
NXY85_RS15765	COG3634	alkyl hydroperoxide reductase activity
NXY85_RS15775	COG1113	amino acid transport
NXY85_RS15800	COG1131	(ABC) transporter
NXY85_RS15805	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXY85_RS15810	COG0038	chloride channel
NXY85_RS15815	COG2323	membrane
NXY85_RS15835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXY85_RS15845	COG1063	alcohol dehydrogenase
NXY85_RS15860	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NXY85_RS15865	COG0456	acetyltransferase
NXY85_RS15870	COG0010	Belongs to the arginase family
NXY85_RS15875	COG0833	amino acid
NXY85_RS15880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXY85_RS15885	COG3829	transcription factor binding
NXY85_RS15895	COG0488	(ABC) transporter
NXY85_RS15910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXY85_RS15915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY85_RS15920	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXY85_RS15925	COG4853	Protein conserved in bacteria
NXY85_RS15930	COG4863	YycH protein
NXY85_RS15935	COG5002	protein histidine kinase activity
NXY85_RS15940	COG0745	RESPONSE REGULATOR receiver
NXY85_RS15975	COG0346	lactoylglutathione lyase activity
NXY85_RS15980	COG0305	Participates in initiation and elongation during chromosome replication
NXY85_RS15995	COG3093	addiction module antidote protein HigA
NXY85_RS16000	COG2807	transmembrane transport
NXY85_RS16010	COG0359	binds to the 23S rRNA
NXY85_RS16015	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NXY85_RS16020	COG4241	membrane
NXY85_RS16030	COG5577	PFAM Coat F domain
NXY85_RS16035	COG1733	regulation of RNA biosynthetic process
NXY85_RS16050	COG2271	Major facilitator Superfamily
NXY85_RS16055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS16075	COG5444	nuclease activity
NXY85_RS16090	COG0473	3-isopropylmalate dehydrogenase activity
NXY85_RS16095	COG1802	Transcriptional regulator
NXY85_RS16100	COG0789	Transcriptional regulator
NXY85_RS16100	COG4978	Transcriptional regulator
NXY85_RS16115	COG2409	Drug exporters of the RND superfamily
NXY85_RS16120	COG2197	response regulator
NXY85_RS16125	COG4585	Histidine kinase
NXY85_RS16135	COG1331	Highly conserved protein containing a thioredoxin domain
NXY85_RS16140	COG0745	RESPONSE REGULATOR receiver
NXY85_RS16145	COG2205	protein histidine kinase activity
NXY85_RS16165	COG2856	Zn peptidase
NXY85_RS16175	COG1331	Highly conserved protein containing a thioredoxin domain
NXY85_RS16180	COG2814	Major facilitator Superfamily
NXY85_RS16180	COG0477	Major facilitator Superfamily
NXY85_RS16185	COG0346	lactoylglutathione lyase activity
NXY85_RS16190	COG1609	Transcriptional regulator
NXY85_RS16195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXY85_RS16200	COG2169	Transcriptional regulator
NXY85_RS16205	COG0708	Exodeoxyribonuclease III
NXY85_RS16210	COG0697	spore germination
NXY85_RS16215	COG1802	Transcriptional regulator
NXY85_RS16225	COG0629	single-stranded DNA binding
NXY85_RS16230	COG0360	Binds together with S18 to 16S ribosomal RNA
NXY85_RS16235	COG0012	GTP binding
NXY85_RS16240	COG0243	molybdopterin cofactor binding
NXY85_RS16245	COG4481	Protein conserved in bacteria
NXY85_RS16250	COG3949	Membrane
NXY85_RS16260	COG1475	DNA binding
NXY85_RS16265	COG1192	Involved in chromosome partitioning
NXY85_RS16275	COG1475	DNA binding
NXY85_RS16280	COG0357	Ribosomal RNA small subunit methyltransferase G
NXY85_RS16285	COG0445	tRNA wobble uridine modification
NXY85_RS16295	COG1847	R3H domain protein
NXY85_RS16300	COG0706	membrane insertase activity
NXY85_RS16305	COG0594	ribonuclease P activity
NXY85_RS16315	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXY85_RS16320	COG0592	DNA-directed DNA polymerase activity
NXY85_RS16325	COG2501	S4 domain
NXY85_RS16330	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXY85_RS16340	COG0187	DNA topoisomerase II activity
NXY85_RS16345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NXY85_RS16380	COG0516	GMP reductase activity
NXY85_RS16380	COG0517	IMP dehydrogenase activity
NXY85_RS16385	COG1686	Belongs to the peptidase S11 family
NXY85_RS16410	COG1428	Deoxynucleoside kinase
NXY85_RS16415	COG1428	Deoxynucleoside kinase
NXY85_RS16420	COG1388	LysM domain
NXY85_RS16420	COG3858	chitin binding
NXY85_RS16425	COG1335	isochorismatase
NXY85_RS16430	COG0590	tRNA wobble adenosine to inosine editing
NXY85_RS16440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXY85_RS16445	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NXY85_RS16450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXY85_RS16495	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NXY85_RS16500	COG3853	Toxic anion resistance protein (TelA)
NXY85_RS16505	COG1982	Orn Lys Arg decarboxylase major
NXY85_RS16510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NXY85_RS16515	COG3870	Protein conserved in bacteria
NXY85_RS16520	COG1728	Protein conserved in bacteria
NXY85_RS16525	COG0470	DNA polymerase III
NXY85_RS16530	COG1774	PSP1 C-terminal conserved region
NXY85_RS16540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXY85_RS16545	COG2827	Endonuclease containing a URI domain
NXY85_RS16550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXY85_RS16555	COG2002	toxin-antitoxin pair type II binding
NXY85_RS16560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY85_RS16560	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY85_RS16565	COG0084	hydrolase, TatD family'
NXY85_RS16570	COG3583	domain protein
NXY85_RS16570	COG3584	3D domain protein
NXY85_RS16575	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NXY85_RS16580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXY85_RS16590	COG4466	Protein conserved in bacteria
NXY85_RS16600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXY85_RS16605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXY85_RS16610	COG0251	oxidation-reduction process
NXY85_RS16625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXY85_RS16630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXY85_RS16635	COG0193	aminoacyl-tRNA hydrolase activity
NXY85_RS16645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NXY85_RS16650	COG2002	toxin-antitoxin pair type II binding
NXY85_RS16655	COG2244	polysaccharide biosynthetic process
NXY85_RS16660	COG3956	TIGRFAM MazG family protein
NXY85_RS16665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXY85_RS16680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NXY85_RS16685	COG1098	S1 RNA binding domain
NXY85_RS16700	COG2208	phosphoserine phosphatase activity
NXY85_RS16705	COG2304	oxidoreductase activity
NXY85_RS16710	COG0515	serine threonine protein kinase
NXY85_RS16715	COG0037	tRNA processing
NXY85_RS16720	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXY85_RS16725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXY85_RS16740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXY85_RS16745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXY85_RS16750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXY85_RS16755	COG0512	Glutamine amidotransferase of anthranilate synthase
NXY85_RS16760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXY85_RS16765	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXY85_RS16770	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NXY85_RS16775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXY85_RS16780	COG1396	sequence-specific DNA binding
NXY85_RS16785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXY85_RS16790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXY85_RS16870	COG4463	regulation of RNA biosynthetic process
NXY85_RS16875	COG3880	PFAM UvrB UvrC protein
NXY85_RS16880	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NXY85_RS16885	COG0542	response to heat
NXY85_RS16890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXY85_RS16895	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NXY85_RS16900	COG4956	integral membrane protein (PIN domain superfamily)
NXY85_RS16905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXY85_RS16910	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXY85_RS16915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXY85_RS16920	COG1045	serine acetyltransferase
NXY85_RS16925	COG0215	cysteine-tRNA ligase activity
NXY85_RS16930	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NXY85_RS16935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXY85_RS16940	COG3688	RNA-binding protein containing a PIN domain
NXY85_RS16945	COG1595	DNA-templated transcription, initiation
NXY85_RS16955	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXY85_RS16960	COG0250	Participates in transcription elongation, termination and antitermination
NXY85_RS16975	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXY85_RS16985	COG2813	Specifically methylates the guanine in position
NXY85_RS16990	COG0085	RNA polymerase activity
NXY85_RS17000	COG1358	cellular component organization or biogenesis
NXY85_RS17010	COG0049	tRNA binding
NXY85_RS17015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXY85_RS17025	COG0596	Alpha beta hydrolase
NXY85_RS17035	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXY85_RS17050	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXY85_RS17080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXY85_RS17105	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXY85_RS17115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXY85_RS17120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXY85_RS17130	COG0200	Binds to the 23S rRNA
NXY85_RS17135	COG0201	protein transport
NXY85_RS17145	COG0024	Methionine aminopeptidase
NXY85_RS17150	COG2163	COG2163 Ribosomal protein L14E L6E L27E
NXY85_RS17160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXY85_RS17170	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXY85_RS17180	COG0203	ribosomal protein L17
NXY85_RS17185	COG1122	ATPase activity
NXY85_RS17190	COG1122	ATPase activity
NXY85_RS17195	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NXY85_RS17200	COG0101	tRNA pseudouridine synthase activity
NXY85_RS17210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXY85_RS17215	COG2226	methyltransferase
NXY85_RS17225	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY85_RS17230	COG0489	protein tyrosine kinase activity
NXY85_RS17240	COG2194	sulfuric ester hydrolase activity
NXY85_RS17245	COG0726	polysaccharide deacetylase
NXY85_RS17275	COG0738	Major facilitator superfamily
NXY85_RS17280	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NXY85_RS17290	COG1063	alcohol dehydrogenase
NXY85_RS17295	COG0659	secondary active sulfate transmembrane transporter activity
NXY85_RS17300	COG0385	Bile acid
NXY85_RS17305	COG2819	hydrolase of the alpha beta superfamily
NXY85_RS17310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS17315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS17320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NXY85_RS17325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NXY85_RS17325	COG2207	Transcriptional regulator
NXY85_RS17330	COG3876	Protein conserved in bacteria
NXY85_RS17335	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY85_RS17340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NXY85_RS17345	COG1263	PTS System
NXY85_RS17345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS17350	COG1737	Transcriptional regulator
NXY85_RS17355	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXY85_RS17360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS17365	COG1683	Conserved Protein
NXY85_RS17395	COG1595	DNA-templated transcription, initiation
NXY85_RS17400	COG5662	AntiSigma factor
NXY85_RS17405	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXY85_RS17410	COG4856	YbbR-like protein
NXY85_RS17415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXY85_RS17425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXY85_RS17430	COG3002	Belongs to the UPF0753 family
NXY85_RS17435	COG0288	reversible hydration of carbon dioxide
NXY85_RS17445	COG5609	conserved protein (DUF2294)
NXY85_RS17450	COG0640	Transcriptional regulator
NXY85_RS17455	COG2814	Major facilitator Superfamily
NXY85_RS17475	COG1413	lyase activity
NXY85_RS17500	COG0076	glutamate decarboxylase activity
NXY85_RS17515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXY85_RS17520	COG2808	Putative FMN-binding domain
NXY85_RS17525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXY85_RS17535	COG1346	cytolysis
NXY85_RS17540	COG1380	Effector of murein hydrolase LrgA
NXY85_RS17545	COG1846	Transcriptional regulator
NXY85_RS17550	COG1113	amino acid transport
NXY85_RS17565	COG2602	Beta-lactamase
NXY85_RS17570	COG2124	cytochrome p450
NXY85_RS17585	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXY85_RS17590	COG0584	glycerophosphoryl diester phosphodiesterase
NXY85_RS17595	COG2271	Major facilitator Superfamily
NXY85_RS17610	COG3409	Peptidoglycan-binding domain 1 protein
NXY85_RS17620	COG0371	Dehydrogenase
NXY85_RS17625	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXY85_RS17635	COG0596	Alpha beta hydrolase
NXY85_RS17640	COG1183	phosphatidylcholine synthase activity
NXY85_RS17645	COG0586	Pfam SNARE associated Golgi protein
NXY85_RS17650	COG0688	phosphatidylethanolamine metabolic process
NXY85_RS17655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXY85_RS17665	COG1404	Belongs to the peptidase S8 family
NXY85_RS17670	COG2312	Erythromycin esterase
NXY85_RS17675	COG2207	Transcriptional regulator
NXY85_RS17680	COG1054	Belongs to the UPF0176 family
NXY85_RS17685	COG1301	dicarboxylic acid transport
NXY85_RS17690	COG1263	PTS System
NXY85_RS17690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS17690	COG2190	(PTS) system
NXY85_RS17695	COG0363	glucosamine-6-phosphate deaminase activity
NXY85_RS17700	COG2188	Transcriptional regulator
NXY85_RS17710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXY85_RS17715	COG0833	amino acid
NXY85_RS17720	COG2040	homocysteine
NXY85_RS17725	COG1115	amino acid carrier protein
NXY85_RS17730	COG2066	Belongs to the glutaminase family
NXY85_RS17735	COG4191	Histidine kinase
NXY85_RS17740	COG0784	Response regulator, receiver
NXY85_RS17745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXY85_RS17750	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS17755	COG2271	Major facilitator Superfamily
NXY85_RS17760	COG4948	Mandelate Racemase Muconate Lactonizing
NXY85_RS17765	COG2186	Transcriptional regulator
NXY85_RS17770	COG2721	sulfolactate sulfo-lyase activity
NXY85_RS17775	COG3173	Aminoglycoside phosphotransferase
NXY85_RS17795	COG0745	RESPONSE REGULATOR receiver
NXY85_RS17805	COG1131	(ABC) transporter
NXY85_RS17830	COG3773	Cell wall hydrolase
NXY85_RS17835	COG3540	Alkaline phosphatase
NXY85_RS17840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXY85_RS17845	COG0805	protein transport
NXY85_RS17855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXY85_RS17860	COG0477	Major facilitator Superfamily
NXY85_RS17865	COG1309	transcriptional regulator
NXY85_RS17870	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NXY85_RS17875	COG3012	SEC-C Motif Domain Protein
NXY85_RS17875	COG1405	negative regulation of cell septum assembly
NXY85_RS17880	COG0667	Aldo Keto reductase
NXY85_RS17890	COG1595	DNA-templated transcription, initiation
NXY85_RS17895	COG0735	belongs to the Fur family
NXY85_RS17900	COG1595	DNA-templated transcription, initiation
NXY85_RS17905	COG1876	peptidase activity
NXY85_RS17910	COG0457	Tetratricopeptide repeat
NXY85_RS17915	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS17920	COG0366	Alpha amylase catalytic
NXY85_RS17925	COG0803	Belongs to the bacterial solute-binding protein 9 family
NXY85_RS17930	COG1121	(ABC) transporter
NXY85_RS17935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXY85_RS17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NXY85_RS17945	COG2310	stress, protein
NXY85_RS17950	COG2310	stress, protein
NXY85_RS17955	COG2310	stress, protein
NXY85_RS17960	COG0861	Integral membrane protein TerC family
NXY85_RS17990	COG3853	Toxic anion resistance protein (TelA)
NXY85_RS17995	COG0477	Major facilitator Superfamily
NXY85_RS18000	COG0517	IMP dehydrogenase activity
NXY85_RS18000	COG4175	Glycine betaine
NXY85_RS18005	COG4176	ABC-type proline glycine betaine transport system permease component
NXY85_RS18010	COG2113	Glycine betaine
NXY85_RS18015	COG1473	amidohydrolase
NXY85_RS18020	COG1288	antiporter activity
NXY85_RS18030	COG0039	L-malate dehydrogenase activity
NXY85_RS18035	COG1620	l-lactate permease
NXY85_RS18040	COG2814	Major facilitator Superfamily
NXY85_RS18045	COG1846	Transcriptional regulator
NXY85_RS18050	COG1280	lysine exporter protein (LysE YggA)
NXY85_RS18055	COG3403	YqcI/YcgG family
NXY85_RS18060	COG1113	amino acid transport
NXY85_RS18065	COG3665	Urea carboxylase-associated protein
NXY85_RS18075	COG1660	Displays ATPase and GTPase activities
NXY85_RS18080	COG1082	Xylose isomerase domain protein TIM barrel
NXY85_RS18085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXY85_RS18095	COG3458	cephalosporin-C deacetylase activity
NXY85_RS18100	COG3541	Predicted nucleotidyltransferase
NXY85_RS18105	COG0506	proline dehydrogenase activity
NXY85_RS18110	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS18115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS18120	COG2508	Transcriptional regulator
NXY85_RS18125	COG3689	TIGRFAM TIGR03943 family protein
NXY85_RS18130	COG0701	Predicted permease
NXY85_RS18135	COG2267	carboxylic ester hydrolase activity
NXY85_RS18140	COG0492	ferredoxin-NADP+ reductase activity
NXY85_RS18145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NXY85_RS18145	COG1587	Uroporphyrinogen-III synthase
NXY85_RS18150	COG2146	nitrite reductase [NAD(P)H] activity
NXY85_RS18155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NXY85_RS18160	COG0243	molybdopterin cofactor binding
NXY85_RS18165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NXY85_RS18170	COG2223	nitrite transmembrane transporter activity
NXY85_RS18175	COG1469	GTP cyclohydrolase I activity
NXY85_RS18180	COG1376	ErfK ybiS ycfS ynhG family protein
NXY85_RS18185	COG0523	cobalamin synthesis protein
NXY85_RS18190	COG0765	amino acid transport
NXY85_RS18195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY85_RS18200	COG1063	alcohol dehydrogenase
NXY85_RS18205	COG1714	RDD family
NXY85_RS18220	COG2723	6-phospho-beta-galactosidase activity
NXY85_RS18230	COG3209	COG3209 Rhs family protein
NXY85_RS18235	COG0840	transmembrane signaling receptor activity
NXY85_RS18235	COG3290	protein histidine kinase activity
NXY85_RS18240	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NXY85_RS18245	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NXY85_RS18250	COG1733	regulation of RNA biosynthetic process
NXY85_RS18255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS18275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS18280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NXY85_RS18285	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NXY85_RS18295	COG0697	spore germination
NXY85_RS18300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXY85_RS18310	COG2364	Membrane
NXY85_RS18315	COG1126	abc transporter atp-binding protein
NXY85_RS18320	COG0765	amino acid transport
NXY85_RS18325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY85_RS18330	COG0583	DNA-binding transcription factor activity
NXY85_RS18335	COG0163	prenyltransferase activity
NXY85_RS18340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NXY85_RS18355	COG0596	Alpha beta hydrolase
NXY85_RS18360	COG3104	oligopeptide transport
NXY85_RS18365	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS18375	COG0697	spore germination
NXY85_RS18385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NXY85_RS18390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NXY85_RS18395	COG0456	acetyltransferase
NXY85_RS18400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY85_RS18405	COG0765	amino acid transport
NXY85_RS18410	COG1126	abc transporter atp-binding protein
NXY85_RS18415	COG1473	amidohydrolase
NXY85_RS18420	COG2079	MmgE PrpD family protein
NXY85_RS18425	COG1136	(ABC) transporter
NXY85_RS18430	COG0577	efflux transmembrane transporter activity
NXY85_RS18435	COG0745	RESPONSE REGULATOR receiver
NXY85_RS18440	COG3850	Histidine kinase
NXY85_RS18440	COG5002	protein histidine kinase activity
NXY85_RS18445	COG0457	Tetratricopeptide repeat
NXY85_RS18465	COG0527	aspartate kinase activity
NXY85_RS18470	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS18475	COG4605	iron ion homeostasis
NXY85_RS18480	COG4604	ABC transporter, ATP-binding protein
NXY85_RS18485	COG4607	ABC-type enterochelin transport system periplasmic component
NXY85_RS18490	COG2814	Major facilitator Superfamily
NXY85_RS18495	COG1309	transcriptional regulator
NXY85_RS18500	COG0457	Tetratricopeptide repeat
NXY85_RS18505	COG0778	Nitroreductase
NXY85_RS18510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NXY85_RS18515	COG0640	Transcriptional regulator
NXY85_RS18525	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NXY85_RS18530	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS18535	COG4975	Glucose uptake
NXY85_RS18540	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS18545	COG4549	nuclear export factor GLE1
NXY85_RS18550	COG1276	copper resistance
NXY85_RS18550	COG2372	response to copper ion
NXY85_RS18555	COG1349	DNA-binding transcription factor activity
NXY85_RS18565	COG2213	PTS system mannitol-specific
NXY85_RS18570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS18575	COG0246	Mannitol dehydrogenase
NXY85_RS18580	COG0412	Dienelactone hydrolase
NXY85_RS18585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXY85_RS18600	COG0561	phosphatase activity
NXY85_RS18605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NXY85_RS18610	COG1914	H( )-stimulated, divalent metal cation uptake system
NXY85_RS18615	COG4336	lyase activity
NXY85_RS18620	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NXY85_RS18625	COG1984	allophanate hydrolase subunit 2
NXY85_RS18630	COG1414	Transcriptional regulator
NXY85_RS18635	COG2755	lipolytic protein G-D-S-L family
NXY85_RS18645	COG2329	Antibiotic biosynthesis monooxygenase
NXY85_RS18650	COG0768	penicillin binding
NXY85_RS18655	COG4989	oxidoreductase activity
NXY85_RS18660	COG3711	transcriptional antiterminator
NXY85_RS18665	COG0318	PFAM AMP-dependent synthetase and ligase
NXY85_RS18670	COG2226	methyltransferase
NXY85_RS18675	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS18685	COG3871	stress protein (general stress protein 26)
NXY85_RS18700	COG2814	Major facilitator Superfamily
NXY85_RS18715	COG1522	sequence-specific DNA binding
NXY85_RS18720	COG0551	DNA topoisomerase type I activity
NXY85_RS18720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXY85_RS18725	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NXY85_RS18730	COG3706	GGDEF domain
NXY85_RS18735	COG5298	Protein conserved in bacteria
NXY85_RS18740	COG1215	transferase activity, transferring glycosyl groups
NXY85_RS18750	COG0531	amino acid
NXY85_RS18760	COG0028	Belongs to the TPP enzyme family
NXY85_RS18785	COG1914	H( )-stimulated, divalent metal cation uptake system
NXY85_RS18790	COG2261	transglycosylase associated protein
NXY85_RS18795	COG4876	unkown
NXY85_RS18800	COG2217	Heavy metal translocating P-type atpase
NXY85_RS18810	COG3729	General stress protein
NXY85_RS18815	COG0662	Cupin 2, conserved barrel domain protein
NXY85_RS18825	COG3546	catalase activity
NXY85_RS18830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NXY85_RS18835	COG3290	protein histidine kinase activity
NXY85_RS18840	COG4565	transcriptional regulatory protein
NXY85_RS18845	COG1301	dicarboxylic acid transport
NXY85_RS18850	COG0628	permease
NXY85_RS18855	COG1131	(ABC) transporter
NXY85_RS18860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NXY85_RS18870	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS18885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NXY85_RS18890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY85_RS18895	COG1181	Belongs to the D-alanine--D-alanine ligase family
NXY85_RS18900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXY85_RS18910	COG0513	Belongs to the DEAD box helicase family
NXY85_RS18915	COG3402	PFAM membrane-flanked domain
NXY85_RS18920	COG3428	Bacterial PH domain
NXY85_RS18925	COG0705	Rhomboid family
NXY85_RS18930	COG0736	holo-[acyl-carrier-protein] synthase activity
NXY85_RS18935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NXY85_RS18940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXY85_RS18945	COG0864	Transcriptional regulator
NXY85_RS18950	COG2337	Toxic component of a toxin-antitoxin (TA) module
NXY85_RS18955	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS18960	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS18965	COG2172	sigma factor antagonist activity
NXY85_RS18970	COG2208	phosphoserine phosphatase activity
NXY85_RS18975	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS18980	COG2172	sigma factor antagonist activity
NXY85_RS18985	COG1191	sigma factor activity
NXY85_RS18990	COG2208	phosphoserine phosphatase activity
NXY85_RS18995	COG2183	response to ionizing radiation
NXY85_RS19005	COG3091	SprT-like family
NXY85_RS19065	COG0659	secondary active sulfate transmembrane transporter activity
NXY85_RS19070	COG0589	response to stress
NXY85_RS19075	COG1959	2 iron, 2 sulfur cluster binding
NXY85_RS19095	COG3048	D-serine ammonia-lyase activity
NXY85_RS19105	COG1316	TRANSCRIPTIONal
NXY85_RS19120	COG5002	protein histidine kinase activity
NXY85_RS19125	COG0745	RESPONSE REGULATOR receiver
NXY85_RS19130	COG3239	Fatty acid desaturase
NXY85_RS19140	COG1278	Cold shock
NXY85_RS19145	COG1329	Transcriptional regulator
NXY85_RS19155	COG2315	Protein conserved in bacteria
NXY85_RS19175	COG2364	Membrane
NXY85_RS19180	COG1846	Transcriptional regulator
NXY85_RS19185	COG0456	acetyltransferase
NXY85_RS19195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXY85_RS19205	COG2814	Major facilitator Superfamily
NXY85_RS19225	COG0697	spore germination
NXY85_RS19230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXY85_RS19235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY85_RS19250	COG0640	Transcriptional regulator
NXY85_RS19255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NXY85_RS19260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXY85_RS19270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS19295	COG1621	beta-fructofuranosidase activity
NXY85_RS19300	COG3716	PTS system mannose fructose sorbose family IID component
NXY85_RS19305	COG3715	PTS system
NXY85_RS19310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS19315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS19320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NXY85_RS19320	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NXY85_RS19330	COG1846	Transcriptional regulator
NXY85_RS19335	COG1033	growth of symbiont in host cell
NXY85_RS19335	COG2409	Drug exporters of the RND superfamily
NXY85_RS19340	COG3711	transcriptional antiterminator
NXY85_RS19340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS19345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NXY85_RS19345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NXY85_RS19345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NXY85_RS19350	COG1482	cell wall glycoprotein biosynthetic process
NXY85_RS19365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS19370	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NXY85_RS19375	COG1522	sequence-specific DNA binding
NXY85_RS19380	COG0488	(ABC) transporter
NXY85_RS19385	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS19395	COG1942	4-Oxalocrotonate Tautomerase
NXY85_RS19400	COG0583	DNA-binding transcription factor activity
NXY85_RS19405	COG5566	PFAM Mor transcription activator
NXY85_RS19425	COG2602	Beta-lactamase
NXY85_RS19435	COG2814	Major facilitator Superfamily
NXY85_RS19445	COG3858	chitin binding
NXY85_RS19445	COG1388	LysM domain
NXY85_RS19450	COG1819	glycosyl
NXY85_RS19465	COG1785	Belongs to the alkaline phosphatase family
NXY85_RS19475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NXY85_RS19480	COG1125	glycine betaine transport
NXY85_RS19480	COG0517	IMP dehydrogenase activity
NXY85_RS19485	COG1174	glycine betaine transport
NXY85_RS19490	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS19495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS19510	COG2814	Major facilitator Superfamily
NXY85_RS19515	COG2186	Transcriptional regulator
NXY85_RS19520	COG2807	transmembrane transport
NXY85_RS19535	COG1378	Sugar-specific transcriptional regulator TrmB
NXY85_RS19575	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXY85_RS19580	COG0802	atpase or kinase
NXY85_RS19585	COG1214	PFAM Peptidase M22, glycoprotease
NXY85_RS19590	COG0456	acetyltransferase
NXY85_RS19595	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXY85_RS19600	COG0488	(ABC) transporter
NXY85_RS19605	COG0315	cyclic pyranopterin monophosphate synthase activity
NXY85_RS19615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXY85_RS19620	COG0805	protein transport
NXY85_RS19630	COG1266	CAAX protease self-immunity
NXY85_RS19670	COG0457	Tetratricopeptide repeat
NXY85_RS19675	COG1063	alcohol dehydrogenase
NXY85_RS19680	COG2211	Major facilitator Superfamily
NXY85_RS19685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY85_RS19690	COG1842	Phage shock protein A
NXY85_RS19695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXY85_RS19700	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NXY85_RS19705	COG4260	virion core protein, lumpy skin disease virus
NXY85_RS19715	COG1595	DNA-templated transcription, initiation
NXY85_RS19725	COG0778	Nitroreductase
NXY85_RS19730	COG1846	Transcriptional regulator
NXY85_RS19735	COG2814	Major facilitator Superfamily
NXY85_RS19740	COG1063	alcohol dehydrogenase
NXY85_RS19745	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NXY85_RS19750	COG0823	Involved in the tonB-independent uptake of proteins
NXY85_RS19760	COG2267	carboxylic ester hydrolase activity
NXY85_RS19770	COG2132	Multicopper oxidase
NXY85_RS19775	COG1113	amino acid transport
NXY85_RS19785	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NXY85_RS19790	COG0714	Associated with various cellular activities
NXY85_RS19795	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NXY85_RS19800	COG1305	Transglutaminase-like
NXY85_RS19805	COG0519	Catalyzes the synthesis of GMP from XMP
NXY85_RS19805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXY85_RS19825	COG1131	(ABC) transporter
NXY85_RS19835	COG2252	PERMEase
NXY85_RS19840	COG3064	Membrane
NXY85_RS19850	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NXY85_RS19860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXY85_RS19865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NXY85_RS19870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NXY85_RS19875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXY85_RS19880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NXY85_RS19885	COG0047	phosphoribosylformylglycinamidine synthase activity
NXY85_RS19890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NXY85_RS19895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXY85_RS19905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NXY85_RS19910	COG0138	bifunctional purine biosynthesis protein purh
NXY85_RS19915	COG0151	Belongs to the GarS family
NXY85_RS19920	COG1522	sequence-specific DNA binding
NXY85_RS19935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NXY85_RS19940	COG1470	cell adhesion involved in biofilm formation
NXY85_RS19945	COG4496	protein, YerC YecD
NXY85_RS19950	COG0069	glutamate synthase activity
NXY85_RS19955	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NXY85_RS19960	COG0210	DNA helicase
NXY85_RS19965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXY85_RS19970	COG4851	CamS sex pheromone cAM373 precursor
NXY85_RS19975	COG2211	Major facilitator Superfamily
NXY85_RS19985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NXY85_RS19995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NXY85_RS20000	COG1250	3-hydroxyacyl-CoA dehydrogenase
NXY85_RS20015	COG1960	acyl-CoA dehydrogenase activity
NXY85_RS20035	COG0300	oxidoreductase activity
NXY85_RS20035	COG4221	oxidoreductase activity
NXY85_RS20035	COG3321	synthase
NXY85_RS20035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXY85_RS20045	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NXY85_RS20050	COG1785	Belongs to the alkaline phosphatase family
NXY85_RS20055	COG1285	pathogenesis
NXY85_RS20060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY85_RS20070	COG0154	amidase activity
NXY85_RS20080	COG1309	transcriptional regulator
NXY85_RS20085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXY85_RS20090	COG1597	lipid kinase activity
NXY85_RS20095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXY85_RS20120	COG5444	nuclease activity
NXY85_RS20125	COG0457	Tetratricopeptide repeat
NXY85_RS20145	COG5444	nuclease activity
NXY85_RS20155	COG0457	Tetratricopeptide repeat
NXY85_RS20185	COG3546	catalase activity
NXY85_RS20190	COG0454	-acetyltransferase
NXY85_RS20200	COG5578	integral membrane protein
NXY85_RS20205	COG2972	Histidine kinase
NXY85_RS20210	COG4753	response regulator
NXY85_RS20210	COG2207	Transcriptional regulator
NXY85_RS20215	COG1653	transport
NXY85_RS20220	COG1175	transmembrane transport
NXY85_RS20225	COG0395	ABC-type sugar transport system, permease component
NXY85_RS20230	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXY85_RS20235	COG2207	Transcriptional regulator
NXY85_RS20240	COG2755	lipolytic protein G-D-S-L family
NXY85_RS20250	COG5578	integral membrane protein
NXY85_RS20255	COG3401	FG-GAP repeat protein
NXY85_RS20260	COG3401	FG-GAP repeat protein
NXY85_RS20265	COG0667	Aldo Keto reductase
NXY85_RS20270	COG2755	lipolytic protein G-D-S-L family
NXY85_RS20275	COG1874	Beta-galactosidase
NXY85_RS20285	COG1653	transport
NXY85_RS20290	COG4209	transmembrane transport
NXY85_RS20295	COG0395	ABC-type sugar transport system, permease component
NXY85_RS20300	COG1486	melibiose metabolic process
NXY85_RS20305	COG2323	membrane
NXY85_RS20310	COG2329	Antibiotic biosynthesis monooxygenase
NXY85_RS20315	COG0346	lactoylglutathione lyase activity
NXY85_RS20320	COG1366	Belongs to the anti-sigma-factor antagonist family
NXY85_RS20325	COG5583	Uncharacterized small protein (DUF2292)
NXY85_RS20330	COG0196	riboflavin kinase activity
NXY85_RS20335	COG0670	Belongs to the BI1 family
NXY85_RS20345	COG2124	cytochrome p450
NXY85_RS20345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NXY85_RS20360	COG1131	(ABC) transporter
NXY85_RS20405	COG4106	trans-aconitate 2-methyltransferase activity
NXY85_RS20410	COG1368	sulfuric ester hydrolase activity
NXY85_RS20415	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXY85_RS20420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY85_RS20425	COG1442	glycosyl transferase family 8
NXY85_RS20430	COG1216	Glycosyl transferase, family 2
NXY85_RS20435	COG1442	glycosyl transferase family 8
NXY85_RS20440	COG2223	nitrite transmembrane transporter activity
NXY85_RS20445	COG0531	amino acid
NXY85_RS20450	COG1012	belongs to the aldehyde dehydrogenase family
NXY85_RS20455	COG0840	transmembrane signaling receptor activity
NXY85_RS20460	COG0463	Glycosyl transferase, family 2
NXY85_RS20465	COG0488	(ABC) transporter
NXY85_RS20470	COG0789	Transcriptional regulator
NXY85_RS20475	COG2814	Major facilitator Superfamily
NXY85_RS20480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXY85_RS20485	COG0488	(ABC) transporter
NXY85_RS20490	COG0513	Belongs to the DEAD box helicase family
NXY85_RS20495	COG2130	NADP-dependent
NXY85_RS20500	COG1120	ATPase activity
NXY85_RS20505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS20510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS20515	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NXY85_RS20530	COG3866	Pectate lyase
NXY85_RS20540	COG0471	metal ion transport
NXY85_RS20545	COG3290	protein histidine kinase activity
NXY85_RS20550	COG4565	transcriptional regulatory protein
NXY85_RS20555	COG3181	Tripartite tricarboxylate transporter family receptor
NXY85_RS20560	COG2851	Citrate transporter
NXY85_RS20565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY85_RS20570	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NXY85_RS20575	COG1254	Belongs to the acylphosphatase family
NXY85_RS20580	COG2258	MOSC domain
NXY85_RS20600	COG0024	Methionine aminopeptidase
NXY85_RS20605	COG1263	PTS System
NXY85_RS20605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS20610	COG1368	sulfuric ester hydrolase activity
NXY85_RS20620	COG1115	amino acid carrier protein
NXY85_RS20625	COG1263	PTS System
NXY85_RS20625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS20630	COG0366	Alpha amylase catalytic
NXY85_RS20635	COG2188	Transcriptional regulator
NXY85_RS20640	COG0778	Nitroreductase
NXY85_RS20645	COG0737	Belongs to the 5'-nucleotidase family
NXY85_RS20650	COG0693	protein deglycase activity
NXY85_RS20660	COG4840	Belongs to the UPF0435 family
NXY85_RS20665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXY85_RS20670	COG4980	gas vesicle protein
NXY85_RS20675	COG1295	ribonuclease BN
NXY85_RS20680	COG0477	Major facilitator Superfamily
NXY85_RS20685	COG0387	Pfam Sodium calcium exchanger
NXY85_RS20695	COG0668	transmembrane transport
NXY85_RS20700	COG0535	radical SAM domain protein
NXY85_RS20710	COG0726	polysaccharide deacetylase
NXY85_RS20715	COG2084	Dehydrogenase
NXY85_RS20725	COG0598	Magnesium transport protein CorA
NXY85_RS20730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NXY85_RS20745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXY85_RS20750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXY85_RS20755	COG4637	Psort location Cytoplasmic, score
NXY85_RS20760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NXY85_RS20765	COG0022	dehydrogenase e1 component
NXY85_RS20770	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXY85_RS20775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXY85_RS20780	COG3284	Transcriptional regulator
NXY85_RS20790	COG1742	UPF0060 membrane protein
NXY85_RS20810	COG4842	Belongs to the WXG100 family
NXY85_RS20815	COG1486	melibiose metabolic process
NXY85_RS20820	COG1737	Transcriptional regulator
NXY85_RS20825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NXY85_RS20825	COG1263	PTS System
NXY85_RS20830	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY85_RS20835	COG1132	(ABC) transporter
NXY85_RS20840	COG1132	(ABC) transporter
NXY85_RS20845	COG2259	Doxx family
NXY85_RS20850	COG2514	catechol 2,3-dioxygenase activity
NXY85_RS20860	COG1695	Transcriptional regulator
NXY85_RS20865	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NXY85_RS20870	COG2732	(Barnase) inhibitor
NXY85_RS20880	COG2318	DinB family
NXY85_RS20885	COG2814	Major facilitator Superfamily
NXY85_RS20890	COG1846	Transcriptional regulator
NXY85_RS20895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NXY85_RS20895	COG0392	lysyltransferase activity
NXY85_RS20900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NXY85_RS20905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS20910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY85_RS20920	COG0778	Nitroreductase
NXY85_RS20935	COG1090	epimerase
NXY85_RS20940	COG2137	regulation of response to DNA damage stimulus
NXY85_RS20950	COG2814	Major facilitator Superfamily
NXY85_RS20965	COG3103	Sh3 type 3 domain protein
NXY85_RS20970	COG5658	integral membrane protein
NXY85_RS20975	COG0596	Alpha beta hydrolase
NXY85_RS20980	COG0463	Glycosyl transferase, family 2
NXY85_RS20985	COG4485	Bacterial membrane protein, YfhO
NXY85_RS20990	COG1988	membrane-bound metal-dependent
NXY85_RS20995	COG1194	a g-specific adenine glycosylase
NXY85_RS21005	COG1028	Short-chain dehydrogenase reductase Sdr
NXY85_RS21020	COG3557	Belongs to the UPF0374 family
NXY85_RS21025	COG1132	(ABC) transporter
NXY85_RS21030	COG4129	membrane
NXY85_RS21035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NXY85_RS21040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXY85_RS21045	COG0735	belongs to the Fur family
NXY85_RS21155	COG1063	alcohol dehydrogenase
NXY85_RS21170	COG4326	sporulation control protein
NXY85_RS21175	COG3340	Belongs to the peptidase S51 family
NXY85_RS21180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXY85_RS21190	COG0753	catalase activity
NXY85_RS21195	COG1116	anion transmembrane transporter activity
NXY85_RS21200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NXY85_RS21205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NXY85_RS21215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXY85_RS21225	COG1476	TRANSCRIPTIONal
NXY85_RS21235	COG3382	B3 4 domain protein
NXY85_RS21240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXY85_RS21250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NXY85_RS21255	COG0789	Transcriptional regulator
NXY85_RS21260	COG1664	Polymer-forming cytoskeletal
NXY85_RS21265	COG1664	Polymer-forming cytoskeletal
NXY85_RS21270	COG2766	serine protein kinase
NXY85_RS21275	COG2718	Belongs to the UPF0229 family
NXY85_RS21280	COG1846	Transcriptional regulator
NXY85_RS21285	COG1566	PFAM secretion protein HlyD family protein
NXY85_RS21290	COG2814	Major facilitator Superfamily
NXY85_RS21295	COG0655	NAD(P)H dehydrogenase (quinone) activity
NXY85_RS21310	COG1725	Transcriptional regulator
NXY85_RS21315	COG1131	(ABC) transporter
NXY85_RS21320	COG1131	(ABC) transporter
NXY85_RS21325	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NXY85_RS21330	COG1278	Cold shock
NXY85_RS21345	COG1464	Belongs to the NlpA lipoprotein family
NXY85_RS21350	COG3706	GGDEF domain
NXY85_RS21355	COG1823	symporter activity
NXY85_RS21375	COG5577	PFAM Coat F domain
NXY85_RS21385	COG4085	toxin activity
NXY85_RS21385	COG0737	Belongs to the 5'-nucleotidase family
NXY85_RS21385	COG1525	nuclease
NXY85_RS21390	COG3764	Sortase (surface protein transpeptidase)
NXY85_RS21395	COG0564	pseudouridine synthase activity
NXY85_RS21405	COG0517	IMP dehydrogenase activity
NXY85_RS21410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXY85_RS21415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXY85_RS21415	COG3153	acetyltransferase
NXY85_RS21425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXY85_RS21430	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NXY85_RS21435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXY85_RS21440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NXY85_RS21445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family