locus-tag	class	description
BBEV_RS00015	COG0592	DNA-directed DNA polymerase activity
BBEV_RS00020	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBEV_RS00025	COG0594	ribonuclease P activity
BBEV_RS00030	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBEV_RS00035	COG0706	membrane insertase activity
BBEV_RS00040	COG1847	R3H domain protein
BBEV_RS00045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBEV_RS00050	COG0445	tRNA wobble uridine modification
BBEV_RS00060	COG1475	DNA binding
BBEV_RS00065	COG1192	Involved in chromosome partitioning
BBEV_RS00070	COG1475	DNA binding
BBEV_RS00075	COG1104	cysteine desulfurase activity
BBEV_RS00080	COG1811	Na channel or pump
BBEV_RS00085	COG4481	Protein conserved in bacteria
BBEV_RS00090	COG0012	GTP binding
BBEV_RS00095	COG0360	Binds together with S18 to 16S ribosomal RNA
BBEV_RS00100	COG0629	single-stranded DNA binding
BBEV_RS00105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBEV_RS00110	COG4241	membrane
BBEV_RS00115	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BBEV_RS00120	COG0359	binds to the 23S rRNA
BBEV_RS00125	COG0305	Participates in initiation and elongation during chromosome replication
BBEV_RS00130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBEV_RS00170	COG0745	RESPONSE REGULATOR receiver
BBEV_RS00175	COG5002	protein histidine kinase activity
BBEV_RS00180	COG4863	YycH protein
BBEV_RS00185	COG4853	Protein conserved in bacteria
BBEV_RS00190	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBEV_RS00195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBEV_RS00210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBEV_RS00220	COG1088	dTDP-glucose 4,6-dehydratase activity
BBEV_RS00230	COG1187	pseudouridine synthase activity
BBEV_RS00235	COG0579	oxidoreductase
BBEV_RS00240	COG4251	negative regulation of phosphorylation
BBEV_RS00240	COG3706	GGDEF domain
BBEV_RS00240	COG5001	Diguanylate cyclase
BBEV_RS00240	COG2203	Gaf domain
BBEV_RS00250	COG1131	(ABC) transporter
BBEV_RS00260	COG3239	Fatty acid desaturase
BBEV_RS00265	COG4585	Histidine kinase
BBEV_RS00270	COG2197	response regulator
BBEV_RS00275	COG2199	diguanylate cyclase activity
BBEV_RS00285	COG0493	'glutamate synthase
BBEV_RS00295	COG2897	thiosulfate sulfurtransferase activity
BBEV_RS00300	COG0398	Pfam SNARE associated Golgi protein
BBEV_RS00305	COG4134	Bacterial extracellular solute-binding protein
BBEV_RS00320	COG3842	ATPase activity
BBEV_RS00330	COG4608	Belongs to the ABC transporter superfamily
BBEV_RS00335	COG0444	Belongs to the ABC transporter superfamily
BBEV_RS00340	COG0601	transmembrane transport
BBEV_RS00345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_RS00350	COG0747	negative chemotaxis
BBEV_RS00355	COG0527	aspartate kinase activity
BBEV_RS00370	COG0561	phosphatase activity
BBEV_RS00375	COG0083	homoserine kinase activity
BBEV_RS00380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBEV_RS00385	COG0460	homoserine dehydrogenase
BBEV_RS00415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BBEV_RS00420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBEV_RS00425	COG1794	racemase activity, acting on amino acids and derivatives
BBEV_RS00445	COG1072	(Pantothenic acid kinase))
BBEV_RS00450	COG0251	oxidation-reduction process
BBEV_RS00455	COG3314	Sporulation integral membrane protein YlbJ
BBEV_RS00460	COG2309	aminopeptidase activity
BBEV_RS00465	COG1368	sulfuric ester hydrolase activity
BBEV_RS00480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBEV_RS00485	COG0840	transmembrane signaling receptor activity
BBEV_RS00505	COG1621	beta-fructofuranosidase activity
BBEV_RS00510	COG2201	protein-glutamate methylesterase activity
BBEV_RS00515	COG2084	Dehydrogenase
BBEV_RS00520	COG5002	protein histidine kinase activity
BBEV_RS00525	COG0702	epimerase
BBEV_RS00540	COG0456	acetyltransferase
BBEV_RS00545	COG2363	Small membrane protein
BBEV_RS00550	COG3253	May function as heme-dependent peroxidase
BBEV_RS00555	COG1024	Enoyl-CoA hydratase
BBEV_RS00560	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_RS00560	COG1902	pentaerythritol trinitrate reductase activity
BBEV_RS00565	COG0280	phosphate acetyltransferase
BBEV_RS00570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BBEV_RS00580	COG0095	Lipoate-protein ligase
BBEV_RS00585	COG4844	belongs to the
BBEV_RS00590	COG1078	dGTPase activity
BBEV_RS00610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BBEV_RS00615	COG0010	Belongs to the arginase family
BBEV_RS00635	COG0601	transmembrane transport
BBEV_RS00640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_RS00645	COG0444	Belongs to the ABC transporter superfamily
BBEV_RS00650	COG4608	Belongs to the ABC transporter superfamily
BBEV_RS00655	COG3620	sequence-specific DNA binding
BBEV_RS00665	COG0018	arginyl-trna synthetase
BBEV_RS00670	COG0840	transmembrane signaling receptor activity
BBEV_RS00670	COG3290	protein histidine kinase activity
BBEV_RS00675	COG1349	DNA-binding transcription factor activity
BBEV_RS00680	COG3395	kinase activity
BBEV_RS00685	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BBEV_RS00690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBEV_RS00700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBEV_RS00700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBEV_RS00705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBEV_RS00705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBEV_RS00710	COG1725	Transcriptional regulator
BBEV_RS00715	COG1131	(ABC) transporter
BBEV_RS00725	COG1132	(ABC) transporter
BBEV_RS00740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BBEV_RS00750	COG0247	lactate metabolic process
BBEV_RS00750	COG2181	nitrate reductase activity
BBEV_RS00755	COG0183	Belongs to the thiolase family
BBEV_RS00760	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBEV_RS00765	COG1960	acyl-CoA dehydrogenase activity
BBEV_RS00770	COG1960	acyl-CoA dehydrogenase activity
BBEV_RS00780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBEV_RS00780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBEV_RS00780	COG1703	isobutyryl-CoA mutase activity
BBEV_RS00785	COG3343	RNA polymerase activity
BBEV_RS00790	COG0504	CTP synthase activity
BBEV_RS00800	COG2204	response regulator
BBEV_RS00810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBEV_RS00815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBEV_RS00820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBEV_RS00825	COG0254	rRNA binding
BBEV_RS00830	COG1435	thymidine kinase activity
BBEV_RS00835	COG0840	transmembrane signaling receptor activity
BBEV_RS00840	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_RS00845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBEV_RS00850	COG2890	protein-(glutamine-N5) methyltransferase activity
BBEV_RS00855	COG0009	L-threonylcarbamoyladenylate synthase
BBEV_RS00865	COG0840	transmembrane signaling receptor activity
BBEV_RS00870	COG0698	ribose 5-phosphate isomerase
BBEV_RS00885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBEV_RS00890	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBEV_RS00895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBEV_RS00910	COG0356	it plays a direct role in the translocation of protons across the membrane
BBEV_RS00925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBEV_RS00930	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBEV_RS00935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBEV_RS00940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBEV_RS00945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBEV_RS00955	COG1879	ABC-type sugar transport system periplasmic component
BBEV_RS00960	COG2972	Histidine kinase
BBEV_RS00965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBEV_RS00965	COG2207	Transcriptional regulator
BBEV_RS00970	COG4213	ABC transporter substrate-binding protein
BBEV_RS00975	COG1129	ABC transporter
BBEV_RS00980	COG4214	carbohydrate transport
BBEV_RS00990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBEV_RS00995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBEV_RS01000	COG0649	NAD binding
BBEV_RS01005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BBEV_RS01015	COG0839	Belongs to the complex I subunit 6 family
BBEV_RS01020	COG0713	ATP synthesis coupled electron transport
BBEV_RS01025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BBEV_RS01035	COG1007	ATP synthesis coupled electron transport
BBEV_RS01045	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBEV_RS01050	COG1077	Cell shape determining protein MreB Mrl
BBEV_RS01055	COG4786	Flagellar basal body rod
BBEV_RS01090	COG2244	polysaccharide biosynthetic process
BBEV_RS01100	COG3883	PFAM NLP P60 protein
BBEV_RS01100	COG0791	NLP P60 protein
BBEV_RS01105	COG1316	TRANSCRIPTIONal
BBEV_RS01110	COG0791	NLP P60 protein
BBEV_RS01110	COG1388	LysM domain
BBEV_RS01115	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBEV_RS01125	COG2843	Capsule synthesis protein
BBEV_RS01145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBEV_RS01150	COG0778	Nitroreductase
BBEV_RS01185	COG1609	Transcriptional regulator
BBEV_RS01190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBEV_RS01195	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BBEV_RS01220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBEV_RS01240	COG3944	biosynthesis protein
BBEV_RS01245	COG0489	protein tyrosine kinase activity
BBEV_RS01250	COG4464	protein tyrosine phosphatase activity
BBEV_RS01255	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBEV_RS01270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBEV_RS01275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBEV_RS01320	COG1216	Glycosyl transferase, family 2
BBEV_RS01320	COG1442	glycosyl transferase family 8
BBEV_RS01345	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBEV_RS01375	COG1484	DNA-dependent DNA replication
BBEV_RS01390	COG1316	TRANSCRIPTIONal
BBEV_RS01410	COG2340	Cysteine-rich secretory protein family
BBEV_RS01415	COG2385	sporulation resulting in formation of a cellular spore
BBEV_RS01415	COG2247	cell wall binding repeat
BBEV_RS01430	COG1404	Belongs to the peptidase S8 family
BBEV_RS01435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BBEV_RS01455	COG0463	Glycosyl transferase, family 2
BBEV_RS01490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBEV_RS01495	COG2385	sporulation resulting in formation of a cellular spore
BBEV_RS01500	COG1316	TRANSCRIPTIONal
BBEV_RS01505	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBEV_RS01505	COG2247	cell wall binding repeat
BBEV_RS01520	COG0405	Gamma-glutamyltransferase
BBEV_RS01565	COG0464	growth
BBEV_RS01570	COG1523	belongs to the glycosyl hydrolase 13 family
BBEV_RS01575	COG0737	Belongs to the 5'-nucleotidase family
BBEV_RS01590	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BBEV_RS01610	COG1476	TRANSCRIPTIONal
BBEV_RS01640	COG0243	molybdopterin cofactor binding
BBEV_RS01645	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS01660	COG0243	molybdopterin cofactor binding
BBEV_RS01665	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS01710	COG0791	NLP P60 protein
BBEV_RS01710	COG3883	PFAM NLP P60 protein
BBEV_RS01715	COG1653	transport
BBEV_RS01735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBEV_RS01740	COG0477	Major facilitator Superfamily
BBEV_RS01755	COG0445	tRNA wobble uridine modification
BBEV_RS01770	COG1175	transmembrane transport
BBEV_RS01775	COG0395	ABC-type sugar transport system, permease component
BBEV_RS01785	COG2207	Transcriptional regulator
BBEV_RS01795	COG1472	Belongs to the glycosyl hydrolase 3 family
BBEV_RS01820	COG0745	RESPONSE REGULATOR receiver
BBEV_RS01835	COG1388	LysM domain
BBEV_RS01835	COG0791	NLP P60 protein
BBEV_RS01850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_RS01860	COG3037	sugar-specific permease SgaT UlaA
BBEV_RS01865	COG0561	phosphatase activity
BBEV_RS01870	COG2258	MOSC domain
BBEV_RS01890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBEV_RS01900	COG2508	Transcriptional regulator
BBEV_RS01915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBEV_RS01920	COG1869	D-ribose catabolic process
BBEV_RS01925	COG1129	ABC transporter
BBEV_RS01930	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBEV_RS01935	COG1879	ABC-type sugar transport system periplasmic component
BBEV_RS01965	COG1523	belongs to the glycosyl hydrolase 13 family
BBEV_RS02005	COG3046	protein related to deoxyribodipyrimidine photolyase
BBEV_RS02010	COG1349	DNA-binding transcription factor activity
BBEV_RS02015	COG1105	Belongs to the carbohydrate kinase PfkB family
BBEV_RS02020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBEV_RS02020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBEV_RS02020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_RS02030	COG3706	GGDEF domain
BBEV_RS02040	COG5002	protein histidine kinase activity
BBEV_RS02045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BBEV_RS02055	COG1131	(ABC) transporter
BBEV_RS02060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBEV_RS02070	COG2376	Dihydroxyacetone kinase
BBEV_RS02075	COG1461	Dihydroxyacetone kinase
BBEV_RS02080	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BBEV_RS02090	COG2376	Dihydroxyacetone kinase
BBEV_RS02105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_RS02115	COG3290	protein histidine kinase activity
BBEV_RS02115	COG3829	transcription factor binding
BBEV_RS02120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBEV_RS02125	COG4608	Belongs to the ABC transporter superfamily
BBEV_RS02130	COG0444	Belongs to the ABC transporter superfamily
BBEV_RS02145	COG0747	negative chemotaxis
BBEV_RS02155	COG0701	Predicted permease
BBEV_RS02170	COG0574	Belongs to the PEP-utilizing enzyme family
BBEV_RS02170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBEV_RS02175	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBEV_RS02190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBEV_RS02195	COG0583	DNA-binding transcription factor activity
BBEV_RS02200	COG1802	Transcriptional regulator
BBEV_RS02250	COG1053	succinate dehydrogenase
BBEV_RS02255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBEV_RS02260	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS02265	COG0386	Belongs to the glutathione peroxidase family
BBEV_RS02270	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS02275	COG1620	l-lactate permease
BBEV_RS02285	COG0745	RESPONSE REGULATOR receiver
BBEV_RS02290	COG5002	protein histidine kinase activity
BBEV_RS02305	COG0385	Bile acid
BBEV_RS02320	COG3458	cephalosporin-C deacetylase activity
BBEV_RS02325	COG2318	DinB family
BBEV_RS02335	COG1482	cell wall glycoprotein biosynthetic process
BBEV_RS02340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBEV_RS02345	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBEV_RS02350	COG1984	allophanate hydrolase subunit 2
BBEV_RS02395	COG0326	Molecular chaperone. Has ATPase activity
BBEV_RS02420	COG1363	Peptidase, m42
BBEV_RS02430	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBEV_RS02435	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBEV_RS02440	COG1757	Na H antiporter
BBEV_RS02450	COG0717	Belongs to the dCTP deaminase family
BBEV_RS02460	COG1739	Uncharacterized protein family UPF0029
BBEV_RS02475	COG1307	EDD domain protein, DegV family
BBEV_RS02480	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBEV_RS02485	COG1040	competence protein
BBEV_RS02495	COG2747	anti-sigma28 factor FlgM
BBEV_RS02505	COG1256	bacterial-type flagellum assembly
BBEV_RS02505	COG4786	Flagellar basal body rod
BBEV_RS02510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBEV_RS02520	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BBEV_RS02525	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBEV_RS02535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBEV_RS02545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBEV_RS02550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBEV_RS02560	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BBEV_RS02590	COG1278	Cold shock
BBEV_RS02605	COG1979	alcohol dehydrogenase
BBEV_RS02615	COG1295	ribonuclease BN
BBEV_RS02620	COG2267	carboxylic ester hydrolase activity
BBEV_RS02630	COG0702	epimerase
BBEV_RS02635	COG3437	response regulator, receiver
BBEV_RS02645	COG2203	Gaf domain
BBEV_RS02645	COG2199	diguanylate cyclase activity
BBEV_RS02650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBEV_RS02655	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBEV_RS02665	COG1334	flagellar protein FlaG
BBEV_RS02675	COG1516	flagellar protein fliS
BBEV_RS02700	COG1278	Cold shock
BBEV_RS02705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBEV_RS02710	COG2190	(PTS) system
BBEV_RS02710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBEV_RS02710	COG1263	PTS System
BBEV_RS02720	COG3711	transcriptional antiterminator
BBEV_RS02725	COG0653	protein targeting
BBEV_RS02730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBEV_RS02735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBEV_RS02745	COG2884	Cell division ATP-binding protein ftsE
BBEV_RS02750	COG2177	Part of the ABC transporter FtsEX involved in
BBEV_RS02755	COG0741	lytic transglycosylase activity
BBEV_RS02755	COG0739	heme binding
BBEV_RS02755	COG1196	nuclear chromosome segregation
BBEV_RS02760	COG0793	Belongs to the peptidase S41A family
BBEV_RS02760	COG3409	Peptidoglycan-binding domain 1 protein
BBEV_RS02765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBEV_RS02770	COG0556	nucleotide-excision repair
BBEV_RS02775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBEV_RS02780	COG3595	metallopeptidase activity
BBEV_RS02785	COG1983	PspC domain protein
BBEV_RS02790	COG1950	PFAM Membrane protein of
BBEV_RS02795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBEV_RS02800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBEV_RS02805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBEV_RS02810	COG0546	phosphoglycolate phosphatase activity
BBEV_RS02815	COG0110	maltose O-acetyltransferase activity
BBEV_RS02820	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBEV_RS02825	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BBEV_RS02830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBEV_RS02835	COG0131	Imidazoleglycerol-phosphate dehydratase
BBEV_RS02840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBEV_RS02845	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBEV_RS02850	COG0107	imidazoleglycerol-phosphate synthase activity
BBEV_RS02855	COG0140	phosphoribosyl-ATP diphosphatase activity
BBEV_RS02855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBEV_RS02860	COG1233	COG1233 Phytoene dehydrogenase and related
BBEV_RS02870	COG0492	ferredoxin-NADP+ reductase activity
BBEV_RS02875	COG1660	Displays ATPase and GTPase activities
BBEV_RS02880	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BBEV_RS02885	COG1481	regulation of sporulation
BBEV_RS02890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_RS02895	COG0740	serine-type endopeptidase activity
BBEV_RS02900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BBEV_RS02910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBEV_RS02920	COG0149	triose-phosphate isomerase activity
BBEV_RS02925	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBEV_RS02930	COG0148	phosphopyruvate hydratase activity
BBEV_RS02935	COG0673	inositol 2-dehydrogenase activity
BBEV_RS02940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBEV_RS02950	COG1647	Serine aminopeptidase, S33
BBEV_RS02955	COG0557	exoribonuclease II activity
BBEV_RS02960	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBEV_RS02970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBEV_RS02975	COG0129	dihydroxy-acid dehydratase activity
BBEV_RS02995	COG5002	protein histidine kinase activity
BBEV_RS03000	COG0745	RESPONSE REGULATOR receiver
BBEV_RS03010	COG0201	protein transport
BBEV_RS03015	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBEV_RS03015	COG1024	Enoyl-CoA hydratase
BBEV_RS03020	COG0183	Belongs to the thiolase family
BBEV_RS03025	COG1960	acyl-CoA dehydrogenase activity
BBEV_RS03035	COG0509	glycine decarboxylation via glycine cleavage system
BBEV_RS03045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBEV_RS03050	COG2011	ABC-type metal ion transport system permease component
BBEV_RS03055	COG1464	Belongs to the NlpA lipoprotein family
BBEV_RS03070	COG0396	ATPase activity
BBEV_RS03075	COG0719	Fe-S assembly protein
BBEV_RS03080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBEV_RS03085	COG0822	iron-sulfur transferase activity
BBEV_RS03090	COG0719	Fe-S assembly protein
BBEV_RS03095	COG1801	Protein of unknown function DUF72
BBEV_RS03100	COG0730	response to heat
BBEV_RS03105	COG0737	Belongs to the 5'-nucleotidase family
BBEV_RS03115	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BBEV_RS03120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBEV_RS03125	COG1757	Na H antiporter
BBEV_RS03135	COG4470	Protein conserved in bacteria
BBEV_RS03145	COG1494	fructose-1,6-bisphosphatase
BBEV_RS03150	COG2445	Protein of unknown function DUF86
BBEV_RS03160	COG0647	UMP catabolic process
BBEV_RS03165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBEV_RS03170	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BBEV_RS03175	COG4837	Protein of unknown function (DUF1462)
BBEV_RS03180	COG1252	NADH dehydrogenase
BBEV_RS03185	COG4844	belongs to the
BBEV_RS03195	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_RS03200	COG0316	Belongs to the HesB IscA family
BBEV_RS03205	COG0492	ferredoxin-NADP+ reductase activity
BBEV_RS03210	COG1252	NADH dehydrogenase
BBEV_RS03225	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BBEV_RS03235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBEV_RS03240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBEV_RS03360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBEV_RS03365	COG0644	oxidoreductase
BBEV_RS03375	COG1522	sequence-specific DNA binding
BBEV_RS03380	COG0436	Aminotransferase
BBEV_RS03385	COG1098	S1 RNA binding domain
BBEV_RS03390	COG0166	Belongs to the GPI family
BBEV_RS03395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBEV_RS03410	COG0582	viral genome integration into host DNA
BBEV_RS03415	COG4372	Transposase
BBEV_RS03465	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBEV_RS03480	COG3290	protein histidine kinase activity
BBEV_RS03480	COG0840	transmembrane signaling receptor activity
BBEV_RS03495	COG0733	neurotransmitter:sodium symporter activity
BBEV_RS03515	COG2210	Belongs to the sulfur carrier protein TusA family
BBEV_RS03520	COG1937	Protein conserved in bacteria
BBEV_RS03525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_RS03530	COG1011	Hydrolase
BBEV_RS03535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBEV_RS03560	COG0589	response to stress
BBEV_RS03565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BBEV_RS03575	COG3383	formate dehydrogenase (NAD+) activity
BBEV_RS03575	COG0243	molybdopterin cofactor binding
BBEV_RS03580	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS03595	COG0746	molybdenum cofactor guanylyltransferase activity
BBEV_RS03610	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBEV_RS03615	COG0494	nUDIX hydrolase
BBEV_RS03620	COG1506	peptidase
BBEV_RS03630	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BBEV_RS03635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBEV_RS03640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BBEV_RS03645	COG2267	carboxylic ester hydrolase activity
BBEV_RS03655	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BBEV_RS03660	COG1242	4 iron, 4 sulfur cluster binding
BBEV_RS03665	COG0495	leucyl-tRNA aminoacylation
BBEV_RS03680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBEV_RS03685	COG0432	Pfam Uncharacterised protein family UPF0047
BBEV_RS03690	COG0772	Belongs to the SEDS family
BBEV_RS03695	COG0772	Belongs to the SEDS family
BBEV_RS03700	COG1187	pseudouridine synthase activity
BBEV_RS03705	COG1349	DNA-binding transcription factor activity
BBEV_RS03740	COG0058	SHG alpha-glucan phosphorylase activity
BBEV_RS03745	COG0297	glycogen (starch) synthase activity
BBEV_RS03750	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBEV_RS03755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BBEV_RS03760	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BBEV_RS03765	COG1523	belongs to the glycosyl hydrolase 13 family
BBEV_RS03770	COG0510	thiamine kinase activity
BBEV_RS03775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BBEV_RS03780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_RS03795	COG1363	Peptidase, m42
BBEV_RS03815	COG4848	Belongs to the UPF0354 family
BBEV_RS03835	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBEV_RS03855	COG3118	belongs to the thioredoxin family
BBEV_RS03860	COG0849	cell division
BBEV_RS03865	COG1605	Chorismate mutase
BBEV_RS03865	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBEV_RS03885	COG0454	-acetyltransferase
BBEV_RS03890	COG0517	IMP dehydrogenase activity
BBEV_RS03895	COG0123	including yeast histone deacetylase and acetoin utilization protein
BBEV_RS03910	COG0656	L-ascorbic acid biosynthetic process
BBEV_RS03920	COG1131	(ABC) transporter
BBEV_RS03940	COG0798	PFAM Bile acid sodium symporter
BBEV_RS03965	COG0628	permease
BBEV_RS03980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBEV_RS04000	COG0535	radical SAM domain protein
BBEV_RS04010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_RS04015	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BBEV_RS04020	COG1140	nitrate reductase beta subunit
BBEV_RS04025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BBEV_RS04030	COG2181	nitrate reductase activity
BBEV_RS04035	COG2223	nitrite transmembrane transporter activity
BBEV_RS04040	COG2223	nitrite transmembrane transporter activity
BBEV_RS04065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_RS04075	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BBEV_RS04090	COG1138	Cytochrome C-type biogenesis protein
BBEV_RS04110	COG1131	(ABC) transporter
BBEV_RS04120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBEV_RS04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_RS04130	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BBEV_RS04135	COG0351	phosphomethylpyrimidine kinase
BBEV_RS04140	COG0352	thiamine-phosphate diphosphorylase activity
BBEV_RS04150	COG0708	Exodeoxyribonuclease III
BBEV_RS04155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBEV_RS04185	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BBEV_RS04190	COG0732	type I restriction modification DNA specificity domain
BBEV_RS04195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBEV_RS04235	COG1309	transcriptional regulator
BBEV_RS04290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBEV_RS04295	COG2203	Gaf domain
BBEV_RS04295	COG2199	diguanylate cyclase activity
BBEV_RS04300	COG1956	GAF domain-containing protein
BBEV_RS04305	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBEV_RS04310	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BBEV_RS04320	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BBEV_RS04325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBEV_RS04330	COG0616	signal peptide processing
BBEV_RS04335	COG1714	RDD family
BBEV_RS04340	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BBEV_RS04350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBEV_RS04365	COG0589	response to stress
BBEV_RS04370	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS04375	COG0006	proline dipeptidase activity
BBEV_RS04380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBEV_RS04390	COG4109	DRTGG domain
BBEV_RS04400	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBEV_RS04405	COG0587	DNA-directed DNA polymerase activity
BBEV_RS04410	COG0281	malic enzyme
BBEV_RS04415	COG2186	Transcriptional regulator
BBEV_RS04420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBEV_RS04425	COG0825	malonyl-CoA metabolic process
BBEV_RS04430	COG0205	6-phosphofructokinase activity
BBEV_RS04440	COG3030	protein affecting phage T7 exclusion by the F plasmid
BBEV_RS04445	COG2707	UPF0756 membrane protein
BBEV_RS04450	COG0372	Belongs to the citrate synthase family
BBEV_RS04455	COG0538	isocitrate dehydrogenase activity
BBEV_RS04460	COG0039	L-malate dehydrogenase activity
BBEV_RS04470	COG0745	RESPONSE REGULATOR receiver
BBEV_RS04475	COG5002	protein histidine kinase activity
BBEV_RS04480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBEV_RS04480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBEV_RS04485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBEV_RS04490	COG0237	dephospho-CoA kinase activity
BBEV_RS04495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BBEV_RS04505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBEV_RS04510	COG3611	Membrane attachment protein
BBEV_RS04515	COG1484	DNA-dependent DNA replication
BBEV_RS04520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_RS04525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBEV_RS04535	COG5001	Diguanylate cyclase
BBEV_RS04535	COG1716	ATPase activity
BBEV_RS04540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBEV_RS04545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBEV_RS04550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBEV_RS04565	COG4585	Histidine kinase
BBEV_RS04570	COG2197	response regulator
BBEV_RS04575	COG1131	(ABC) transporter
BBEV_RS04600	COG1363	Peptidase, m42
BBEV_RS04615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBEV_RS04620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBEV_RS04625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_RS04625	COG0072	phenylalanine-tRNA ligase activity
BBEV_RS04640	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BBEV_RS04650	COG1796	DNA polymerase
BBEV_RS04650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBEV_RS04655	COG1193	negative regulation of DNA recombination
BBEV_RS04660	COG3766	membrane
BBEV_RS04670	COG0318	PFAM AMP-dependent synthetase and ligase
BBEV_RS04675	COG0318	PFAM AMP-dependent synthetase and ligase
BBEV_RS04680	COG1309	transcriptional regulator
BBEV_RS04685	COG1024	Enoyl-CoA hydratase
BBEV_RS04690	COG2086	electron transfer activity
BBEV_RS04695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBEV_RS04700	COG3118	belongs to the thioredoxin family
BBEV_RS04705	COG0322	excinuclease ABC activity
BBEV_RS04715	COG1719	4-vinyl reductase, 4VR
BBEV_RS04720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBEV_RS04725	COG2009	succinate dehydrogenase
BBEV_RS04730	COG1053	succinate dehydrogenase
BBEV_RS04735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBEV_RS04740	COG0824	Thioesterase
BBEV_RS04745	COG3711	transcriptional antiterminator
BBEV_RS04750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_RS04755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBEV_RS04760	COG1846	Transcriptional regulator
BBEV_RS04775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBEV_RS04780	COG0622	Phosphoesterase
BBEV_RS04795	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBEV_RS04800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBEV_RS04810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBEV_RS04815	COG1126	abc transporter atp-binding protein
BBEV_RS04820	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BBEV_RS04825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBEV_RS04830	COG0181	hydroxymethylbilane synthase activity
BBEV_RS04840	COG0113	porphobilinogen synthase activity
BBEV_RS04845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBEV_RS04875	COG2197	response regulator
BBEV_RS04880	COG0189	ligase activity
BBEV_RS04885	COG0189	ligase activity
BBEV_RS04890	COG0285	dihydrofolate synthase activity
BBEV_RS04910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBEV_RS04920	COG1459	type II secretion system
BBEV_RS04935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBEV_RS04960	COG1027	Aspartate ammonia-lyase
BBEV_RS04965	COG0424	maF-like protein
BBEV_RS04970	COG2003	Belongs to the UPF0758 family
BBEV_RS04975	COG1077	Cell shape determining protein MreB Mrl
BBEV_RS04980	COG1792	Involved in formation and maintenance of cell shape
BBEV_RS04985	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BBEV_RS04990	COG0850	regulation of cytokinetic process
BBEV_RS04995	COG2894	cell division
BBEV_RS05000	COG1653	transport
BBEV_RS05005	COG1609	Transcriptional regulator
BBEV_RS05020	COG1530	ribonuclease E activity
BBEV_RS05025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BBEV_RS05030	COG2868	ribosomal protein
BBEV_RS05040	COG1234	tRNA 3'-trailer cleavage
BBEV_RS05050	COG0573	inorganic phosphate transmembrane transporter activity
BBEV_RS05055	COG0581	inorganic phosphate transmembrane transporter activity
BBEV_RS05060	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBEV_RS05065	COG0704	Plays a role in the regulation of phosphate uptake
BBEV_RS05085	COG3290	protein histidine kinase activity
BBEV_RS05085	COG0840	transmembrane signaling receptor activity
BBEV_RS05095	COG0243	molybdopterin cofactor binding
BBEV_RS05100	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS05120	COG0686	Belongs to the AlaDH PNT family
BBEV_RS05135	COG5001	Diguanylate cyclase
BBEV_RS05135	COG3300	MHYT domain
BBEV_RS05140	COG0745	RESPONSE REGULATOR receiver
BBEV_RS05145	COG5002	protein histidine kinase activity
BBEV_RS05160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBEV_RS05170	COG3153	acetyltransferase
BBEV_RS05170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBEV_RS05175	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BBEV_RS05180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBEV_RS05190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BBEV_RS05195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBEV_RS05200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBEV_RS05220	COG0066	3-isopropylmalate dehydratase activity
BBEV_RS05225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBEV_RS05230	COG0473	3-isopropylmalate dehydrogenase activity
BBEV_RS05235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBEV_RS05240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BBEV_RS05245	COG0440	acetolactate synthase activity
BBEV_RS05250	COG0028	Belongs to the TPP enzyme family
BBEV_RS05255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBEV_RS05275	COG0667	Aldo Keto reductase
BBEV_RS05290	COG0024	Methionine aminopeptidase
BBEV_RS05300	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_RS05320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBEV_RS05325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBEV_RS05325	COG1522	sequence-specific DNA binding
BBEV_RS05330	COG2313	pseudouridylate synthase activity
BBEV_RS05340	COG1131	(ABC) transporter
BBEV_RS05345	COG1294	oxidase, subunit
BBEV_RS05350	COG1271	oxidase subunit
BBEV_RS05360	COG0702	epimerase
BBEV_RS05370	COG3842	ATPase activity
BBEV_RS05375	COG2508	Transcriptional regulator
BBEV_RS05385	COG4399	Belongs to the UPF0754 family
BBEV_RS05390	COG3679	Belongs to the UPF0342 family
BBEV_RS05405	COG0420	3'-5' exonuclease activity
BBEV_RS05410	COG4717	serine-type aminopeptidase activity
BBEV_RS05415	COG0745	RESPONSE REGULATOR receiver
BBEV_RS05420	COG2770	Histidine kinase
BBEV_RS05420	COG2205	protein histidine kinase activity
BBEV_RS05425	COG3481	metal-dependent phosphohydrolase, HD sub domain
BBEV_RS05445	COG1846	Transcriptional regulator
BBEV_RS05455	COG0537	adenosine 5'-monophosphoramidase activity
BBEV_RS05460	COG1131	(ABC) transporter
BBEV_RS05475	COG1473	amidohydrolase
BBEV_RS05480	COG0785	Cytochrome C biogenesis protein
BBEV_RS05485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBEV_RS05490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BBEV_RS05495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BBEV_RS05500	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BBEV_RS05510	COG3290	protein histidine kinase activity
BBEV_RS05515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBEV_RS05520	COG4492	Belongs to the UPF0735 family
BBEV_RS05525	COG0077	Prephenate dehydratase
BBEV_RS05530	COG0632	four-way junction helicase activity
BBEV_RS05545	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBEV_RS05550	COG0343	queuine tRNA-ribosyltransferase activity
BBEV_RS05555	COG1862	Preprotein translocase
BBEV_RS05575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBEV_RS05575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBEV_RS05580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBEV_RS05590	COG1490	D-aminoacyl-tRNA deacylase activity
BBEV_RS05595	COG0124	histidyl-tRNA synthetase
BBEV_RS05600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBEV_RS05610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BBEV_RS05615	COG1620	l-lactate permease
BBEV_RS05620	COG0247	lactate metabolic process
BBEV_RS05625	COG1139	Iron-sulfur cluster binding protein
BBEV_RS05630	COG1556	Lactate utilization protein
BBEV_RS05640	COG2364	Membrane
BBEV_RS05645	COG1959	2 iron, 2 sulfur cluster binding
BBEV_RS05650	COG1104	cysteine desulfurase activity
BBEV_RS05655	COG0482	sulfurtransferase activity
BBEV_RS05665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBEV_RS05675	COG4472	Bacterial protein of unknown function (DUF965)
BBEV_RS05680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBEV_RS05685	COG3906	Belongs to the UPF0473 family
BBEV_RS05695	COG4122	O-methyltransferase activity
BBEV_RS05700	COG0826	peptidase U32
BBEV_RS05705	COG0826	peptidase U32
BBEV_RS05710	COG0572	uridine kinase
BBEV_RS05715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBEV_RS05725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBEV_RS05740	COG1506	peptidase
BBEV_RS05740	COG0823	Involved in the tonB-independent uptake of proteins
BBEV_RS05740	COG4946	Tricorn protease homolog
BBEV_RS05750	COG0366	Alpha amylase catalytic
BBEV_RS05755	COG0803	Belongs to the bacterial solute-binding protein 9 family
BBEV_RS05760	COG1278	Cold shock
BBEV_RS05765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBEV_RS05780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_RS05780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_RS05790	COG0658	competence protein
BBEV_RS05790	COG2333	competence protein COMEC
BBEV_RS05795	COG5522	Integral membrane protein (intg_mem_TP0381)
BBEV_RS05800	COG0494	nUDIX hydrolase
BBEV_RS05805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBEV_RS05810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBEV_RS05830	COG0484	heat shock protein binding
BBEV_RS05840	COG3300	MHYT domain
BBEV_RS05840	COG5001	Diguanylate cyclase
BBEV_RS05850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBEV_RS05855	COG0656	L-ascorbic acid biosynthetic process
BBEV_RS05860	COG0095	Lipoate-protein ligase
BBEV_RS05865	COG0671	phosphoesterase, PA-phosphatase related
BBEV_RS05875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_RS05880	COG0450	alkyl hydroperoxide reductase
BBEV_RS05885	COG3620	sequence-specific DNA binding
BBEV_RS05885	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBEV_RS05885	COG0617	tRNA 3'-terminal CCA addition
BBEV_RS05890	COG1183	phosphatidylcholine synthase activity
BBEV_RS05895	COG0688	phosphatidylethanolamine metabolic process
BBEV_RS05900	COG3835	regulator
BBEV_RS05905	COG0277	FAD linked oxidase domain protein
BBEV_RS05910	COG0247	lactate metabolic process
BBEV_RS05920	COG1320	monovalent cation:proton antiporter activity
BBEV_RS05925	COG2212	antiporter activity
BBEV_RS05930	COG1863	multisubunit Na H antiporter MnhE subunit
BBEV_RS05935	COG0651	ATP synthesis coupled electron transport
BBEV_RS05940	COG1006	Multisubunit Na H antiporter MnhC subunit
BBEV_RS05945	COG2111	Na H antiporter
BBEV_RS05950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BBEV_RS05950	COG2111	Na H antiporter
BBEV_RS05955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BBEV_RS05960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBEV_RS05970	COG1534	Rna-binding protein
BBEV_RS05975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBEV_RS05980	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBEV_RS05985	COG0799	negative regulation of ribosome biogenesis
BBEV_RS05990	COG2226	methyltransferase
BBEV_RS05995	COG1555	photosystem II stabilization
BBEV_RS05995	COG1596	polysaccharide export
BBEV_RS06000	COG2333	competence protein COMEC
BBEV_RS06000	COG0658	competence protein
BBEV_RS06010	COG1466	dna polymerase III delta subunit
BBEV_RS06015	COG0268	Binds directly to 16S ribosomal RNA
BBEV_RS06020	COG0481	GTPase activity
BBEV_RS06025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBEV_RS06030	COG1420	regulation of RNA biosynthetic process
BBEV_RS06045	COG0484	heat shock protein binding
BBEV_RS06050	COG2264	protein methyltransferase activity
BBEV_RS06055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBEV_RS06060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBEV_RS06065	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BBEV_RS06070	COG1610	YqeY-like protein
BBEV_RS06075	COG1030	water channel activity
BBEV_RS06080	COG4864	UPF0365 protein
BBEV_RS06090	COG1702	phosphate starvation-inducible protein PhoH
BBEV_RS06095	COG1480	7TM receptor with intracellular HD hydrolase
BBEV_RS06105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBEV_RS06110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBEV_RS06115	COG1381	Involved in DNA repair and RecF pathway recombination
BBEV_RS06120	COG0752	glycyl-tRNA synthetase alpha subunit
BBEV_RS06125	COG0751	glycine-tRNA ligase activity
BBEV_RS06130	COG0517	IMP dehydrogenase activity
BBEV_RS06135	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBEV_RS06145	COG0358	DNA primase activity
BBEV_RS06150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBEV_RS06170	COG2384	SAM-dependent methyltransferase
BBEV_RS06175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBEV_RS06180	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBEV_RS06185	COG1329	Transcriptional regulator
BBEV_RS06190	COG0513	Belongs to the DEAD box helicase family
BBEV_RS06195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BBEV_RS06200	COG1121	(ABC) transporter
BBEV_RS06205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBEV_RS06215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBEV_RS06225	COG1121	(ABC) transporter
BBEV_RS06230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBEV_RS06235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBEV_RS06240	COG0735	belongs to the Fur family
BBEV_RS06245	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BBEV_RS06250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BBEV_RS06255	COG4086	secreted protein
BBEV_RS06265	COG5521	maltodextrose utilization protein MalA
BBEV_RS06290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BBEV_RS06300	COG0768	penicillin binding
BBEV_RS06315	COG3481	metal-dependent phosphohydrolase, HD sub domain
BBEV_RS06320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBEV_RS06325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBEV_RS06335	COG0705	Rhomboid family
BBEV_RS06335	COG0457	Tetratricopeptide repeat
BBEV_RS06350	COG1940	carbohydrate kinase activity
BBEV_RS06355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBEV_RS06360	COG0390	transport system, permease component
BBEV_RS06370	COG0011	TIGRFAM Protein of
BBEV_RS06380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_RS06400	COG4980	gas vesicle protein
BBEV_RS06405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBEV_RS06415	COG4537	Required for transformation and DNA binding
BBEV_RS06440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBEV_RS06450	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBEV_RS06455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS06460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBEV_RS06470	COG1321	iron dependent repressor
BBEV_RS06485	COG0006	proline dipeptidase activity
BBEV_RS06490	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBEV_RS06505	COG0511	ligase activity, forming carbon-carbon bonds
BBEV_RS06510	COG0439	Biotin carboxylase
BBEV_RS06515	COG1302	Protein conserved in bacteria
BBEV_RS06520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBEV_RS06530	COG1570	exodeoxyribonuclease VII activity
BBEV_RS06535	COG1722	exodeoxyribonuclease VII activity
BBEV_RS06550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBEV_RS06555	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBEV_RS06560	COG1438	arginine binding
BBEV_RS06565	COG0497	DNA recombination
BBEV_RS06580	COG3829	transcription factor binding
BBEV_RS06580	COG3290	protein histidine kinase activity
BBEV_RS06585	COG0280	phosphate acetyltransferase
BBEV_RS06600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBEV_RS06605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBEV_RS06610	COG0022	dehydrogenase e1 component
BBEV_RS06615	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_RS06640	COG4129	membrane
BBEV_RS06645	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBEV_RS06645	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBEV_RS06650	COG0346	lactoylglutathione lyase activity
BBEV_RS06655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBEV_RS06660	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBEV_RS06675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBEV_RS06685	COG2257	FlhB HrpN YscU SpaS Family
BBEV_RS06700	COG1728	Protein conserved in bacteria
BBEV_RS06705	COG0366	Alpha amylase catalytic
BBEV_RS06710	COG1609	Transcriptional regulator
BBEV_RS06725	COG1902	pentaerythritol trinitrate reductase activity
BBEV_RS06730	COG0517	IMP dehydrogenase activity
BBEV_RS06745	COG0789	Transcriptional regulator
BBEV_RS06760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBEV_RS06765	COG0300	oxidoreductase activity
BBEV_RS06775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBEV_RS06785	COG2414	aldehyde ferredoxin oxidoreductase
BBEV_RS06810	COG1562	ergosterol biosynthetic process
BBEV_RS06840	COG0561	phosphatase activity
BBEV_RS06845	COG2190	(PTS) system
BBEV_RS06850	COG1968	undecaprenyl-diphosphatase activity
BBEV_RS06855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_RS06860	COG0667	Aldo Keto reductase
BBEV_RS06865	COG0494	nUDIX hydrolase
BBEV_RS06870	COG0735	belongs to the Fur family
BBEV_RS06875	COG4974	Belongs to the 'phage' integrase family
BBEV_RS06880	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBEV_RS06895	COG0019	diaminopimelate decarboxylase activity
BBEV_RS06900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBEV_RS06920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBEV_RS06920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBEV_RS06925	COG0307	riboflavin synthase, alpha
BBEV_RS06930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBEV_RS06930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBEV_RS06935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BBEV_RS06940	COG1547	Domain of unknown function (DUF309)
BBEV_RS06945	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBEV_RS06950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBEV_RS06975	COG1187	pseudouridine synthase activity
BBEV_RS06980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_RS06985	COG1333	cytochrome c biogenesis protein
BBEV_RS06990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBEV_RS06995	COG0745	RESPONSE REGULATOR receiver
BBEV_RS07000	COG5002	protein histidine kinase activity
BBEV_RS07005	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBEV_RS07010	COG2096	Adenosyltransferase
BBEV_RS07015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBEV_RS07020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBEV_RS07025	COG2186	Transcriptional regulator
BBEV_RS07035	COG1141	Ferredoxin
BBEV_RS07040	COG4955	Helix-turn-helix domain
BBEV_RS07045	COG0514	ATP-dependent DNA helicase (RecQ)
BBEV_RS07090	COG0789	Transcriptional regulator
BBEV_RS07095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_RS07100	COG0492	ferredoxin-NADP+ reductase activity
BBEV_RS07110	COG2339	peptidase activity
BBEV_RS07125	COG0204	Acyl-transferase
BBEV_RS07145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBEV_RS07150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BBEV_RS07170	COG0302	gtp cyclohydrolase
BBEV_RS07180	COG0142	geranyltranstransferase activity
BBEV_RS07185	COG2226	methyltransferase
BBEV_RS07190	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BBEV_RS07195	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BBEV_RS07200	COG0142	geranyltranstransferase activity
BBEV_RS07205	COG0105	UTP biosynthetic process
BBEV_RS07210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBEV_RS07220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBEV_RS07225	COG4401	Chorismate mutase type I
BBEV_RS07235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBEV_RS07240	COG0134	indole-3-glycerol-phosphate synthase activity
BBEV_RS07245	COG0133	tryptophan synthase activity
BBEV_RS07250	COG0159	tryptophan synthase activity
BBEV_RS07255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBEV_RS07260	COG0287	Prephenate dehydrogenase
BBEV_RS07265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BBEV_RS07275	COG5582	Belongs to the UPF0302 family
BBEV_RS07285	COG0723	plastoquinol--plastocyanin reductase activity
BBEV_RS07290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BBEV_RS07295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BBEV_RS07295	COG2010	Cytochrome c
BBEV_RS07300	COG4347	Protein of unknown function (DUF1405)
BBEV_RS07305	COG2738	Putative neutral zinc metallopeptidase
BBEV_RS07310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBEV_RS07315	COG1694	Mazg nucleotide pyrophosphohydrolase
BBEV_RS07320	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BBEV_RS07325	COG1803	Methylglyoxal synthase
BBEV_RS07335	COG0438	transferase activity, transferring glycosyl groups
BBEV_RS07340	COG0617	tRNA 3'-terminal CCA addition
BBEV_RS07350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BBEV_RS07355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBEV_RS07365	COG1199	ATP-dependent helicase activity
BBEV_RS07365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBEV_RS07370	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_RS07380	COG0436	Aminotransferase
BBEV_RS07385	COG0017	Asparaginyl-tRNA synthetase
BBEV_RS07390	COG3935	DnaD domain protein
BBEV_RS07395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBEV_RS07400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBEV_RS07400	COG4499	WXG100 protein secretion system (Wss), protein YukC
BBEV_RS07405	COG3331	DNA recombination
BBEV_RS07425	COG1335	isochorismatase
BBEV_RS07435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_RS07445	COG1413	lyase activity
BBEV_RS07455	COG3402	PFAM membrane-flanked domain
BBEV_RS07460	COG3428	Bacterial PH domain
BBEV_RS07480	COG2199	diguanylate cyclase activity
BBEV_RS07495	COG1597	lipid kinase activity
BBEV_RS07510	COG0805	protein transport
BBEV_RS07520	COG1428	Deoxynucleoside kinase
BBEV_RS07525	COG1428	Deoxynucleoside kinase
BBEV_RS07540	COG3383	formate dehydrogenase (NAD+) activity
BBEV_RS07550	COG4667	esterase of the alpha-beta hydrolase superfamily
BBEV_RS07560	COG2814	Major facilitator Superfamily
BBEV_RS07575	COG2322	membrane
BBEV_RS07580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBEV_RS07585	COG1554	hydrolase, family 65, central catalytic
BBEV_RS07590	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS07595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBEV_RS07600	COG0114	fumarate hydratase activity
BBEV_RS07615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_RS07620	COG1686	Belongs to the peptidase S11 family
BBEV_RS07630	COG0436	Aminotransferase
BBEV_RS07635	COG0567	Dehydrogenase, E1 component
BBEV_RS07640	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_RS07645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBEV_RS07665	COG2002	toxin-antitoxin pair type II binding
BBEV_RS07680	COG0583	DNA-binding transcription factor activity
BBEV_RS07685	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_RS07690	COG2205	protein histidine kinase activity
BBEV_RS07695	COG4372	Transposase
BBEV_RS07745	COG2508	Transcriptional regulator
BBEV_RS07750	COG0006	proline dipeptidase activity
BBEV_RS07755	COG0626	cystathionine gamma-synthase activity
BBEV_RS07765	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS07770	COG0444	Belongs to the ABC transporter superfamily
BBEV_RS07775	COG4608	Belongs to the ABC transporter superfamily
BBEV_RS07780	COG0747	negative chemotaxis
BBEV_RS07785	COG0601	transmembrane transport
BBEV_RS07790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_RS07795	COG2814	Major facilitator Superfamily
BBEV_RS07805	COG0626	cystathionine gamma-synthase activity
BBEV_RS07810	COG2200	EAL domain
BBEV_RS07815	COG1067	ATP-dependent peptidase activity
BBEV_RS07820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_RS07830	COG1597	lipid kinase activity
BBEV_RS07835	COG0133	tryptophan synthase activity
BBEV_RS07850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBEV_RS07880	COG4152	abc transporter atp-binding protein
BBEV_RS07885	COG1668	transmembrane transport
BBEV_RS07890	COG0525	valine-tRNA ligase activity
BBEV_RS07900	COG2056	Na+-H+ antiporter family
BBEV_RS07910	COG0205	6-phosphofructokinase activity
BBEV_RS07915	COG1765	OsmC-like protein
BBEV_RS07925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BBEV_RS07935	COG0247	lactate metabolic process
BBEV_RS07960	COG0697	spore germination
BBEV_RS07965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BBEV_RS07980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBEV_RS07985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBEV_RS08000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBEV_RS08005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBEV_RS08010	COG0398	Pfam SNARE associated Golgi protein
BBEV_RS08035	COG0488	(ABC) transporter
BBEV_RS08040	COG1454	alcohol dehydrogenase
BBEV_RS08040	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS08055	COG1902	pentaerythritol trinitrate reductase activity
BBEV_RS08055	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_RS08060	COG1764	response to oxidative stress
BBEV_RS08065	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_RS08075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBEV_RS08080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBEV_RS08085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBEV_RS08095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBEV_RS08105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBEV_RS08110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBEV_RS08115	COG0137	argininosuccinate synthase activity
BBEV_RS08120	COG0165	Argininosuccinate lyase
BBEV_RS08130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBEV_RS08145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBEV_RS08155	COG0582	viral genome integration into host DNA
BBEV_RS08160	COG3180	Ammonia monooxygenase
BBEV_RS08165	COG1917	Cupin 2, conserved barrel domain protein
BBEV_RS08170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBEV_RS08180	COG1217	gtp-binding protein TYPA
BBEV_RS08185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBEV_RS08200	COG2848	UPF0210 protein
BBEV_RS08215	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BBEV_RS08225	COG0004	ammonium transporteR
BBEV_RS08235	COG2176	DNA-directed DNA polymerase activity
BBEV_RS08240	COG0371	Dehydrogenase
BBEV_RS08250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBEV_RS08255	COG2996	Protein conserved in bacteria
BBEV_RS08260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBEV_RS08265	COG1408	metallophosphoesterase
BBEV_RS08285	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BBEV_RS08290	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BBEV_RS08300	COG0561	phosphatase activity
BBEV_RS08310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBEV_RS08315	COG0187	DNA topoisomerase II activity
BBEV_RS08320	COG1832	CoA-binding protein
BBEV_RS08325	COG0589	response to stress
BBEV_RS08330	COG1174	glycine betaine transport
BBEV_RS08335	COG1125	glycine betaine transport
BBEV_RS08335	COG0517	IMP dehydrogenase activity
BBEV_RS08340	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BBEV_RS08350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBEV_RS08355	COG0116	Belongs to the methyltransferase superfamily
BBEV_RS08365	COG0328	RNA-DNA hybrid ribonuclease activity
BBEV_RS08370	COG3599	regulation of cell shape
BBEV_RS08375	COG4474	Belongs to the UPF0398 family
BBEV_RS08380	COG2176	DNA-directed DNA polymerase activity
BBEV_RS08390	COG3359	exonuclease
BBEV_RS08395	COG1111	helicase
BBEV_RS08395	COG1205	dead DEAH box helicase
BBEV_RS08405	COG2814	Major facilitator Superfamily
BBEV_RS08420	COG1418	mRNA catabolic process
BBEV_RS08430	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBEV_RS08440	COG0784	Response regulator, receiver
BBEV_RS08440	COG0835	chemotaxis
BBEV_RS08455	COG1131	(ABC) transporter
BBEV_RS08460	COG1725	Transcriptional regulator
BBEV_RS08465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BBEV_RS08470	COG1131	(ABC) transporter
BBEV_RS08515	COG2814	Major facilitator Superfamily
BBEV_RS08520	COG2200	EAL domain
BBEV_RS08525	COG0613	PHP domain protein
BBEV_RS08530	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BBEV_RS08540	COG0824	Thioesterase
BBEV_RS08545	COG0464	growth
BBEV_RS08555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBEV_RS08590	COG5278	phosphoserine phosphatase activity
BBEV_RS08590	COG0840	transmembrane signaling receptor activity
BBEV_RS08595	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_RS08600	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BBEV_RS08610	COG0500	methyltransferase
BBEV_RS08610	COG3615	Tellurite resistance protein tehB
BBEV_RS08625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBEV_RS08630	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBEV_RS08655	COG4846	Membrane protein involved in cytochrome C biogenesis
BBEV_RS08675	COG2217	Heavy metal translocating P-type atpase
BBEV_RS08680	COG1937	Protein conserved in bacteria
BBEV_RS08685	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BBEV_RS08690	COG3763	UPF0154 protein
BBEV_RS08695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBEV_RS08700	COG4224	UPF0291 protein
BBEV_RS08705	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BBEV_RS08715	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBEV_RS08725	COG0174	glutamine synthetase
BBEV_RS08730	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BBEV_RS08735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBEV_RS08740	COG1923	regulation of RNA biosynthetic process
BBEV_RS08745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBEV_RS08750	COG2136	Putative SAM-dependent methyltransferase
BBEV_RS08750	COG2521	methyltransferase
BBEV_RS08755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBEV_RS08760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBEV_RS08765	COG4550	Control of competence regulator ComK, YlbF/YmcA
BBEV_RS08770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBEV_RS08775	COG0156	8-amino-7-oxononanoate synthase activity
BBEV_RS08780	COG1063	alcohol dehydrogenase
BBEV_RS08785	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBEV_RS08790	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBEV_RS08790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBEV_RS08800	COG2359	stage V sporulation protein S
BBEV_RS08805	COG1692	metallophosphoesterase
BBEV_RS08810	COG1418	mRNA catabolic process
BBEV_RS08815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBEV_RS08820	COG0513	Belongs to the DEAD box helicase family
BBEV_RS08825	COG1546	Belongs to the CinA family
BBEV_RS08825	COG1058	Belongs to the CinA family
BBEV_RS08830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBEV_RS08835	COG1426	Protein conserved in bacteria
BBEV_RS08845	COG0300	oxidoreductase activity
BBEV_RS08850	COG0612	Peptidase, M16
BBEV_RS08855	COG0612	Peptidase, M16
BBEV_RS08860	COG2188	Transcriptional regulator
BBEV_RS08865	COG1674	ftsk spoiiie
BBEV_RS08865	COG4980	gas vesicle protein
BBEV_RS08870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBEV_RS08875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBEV_RS08880	COG0527	aspartate kinase activity
BBEV_RS08885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBEV_RS08890	COG0612	Peptidase, M16
BBEV_RS08895	COG1185	polyribonucleotide nucleotidyltransferase activity
BBEV_RS08900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBEV_RS08905	COG0196	riboflavin kinase activity
BBEV_RS08915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBEV_RS08920	COG1550	Protein conserved in bacteria
BBEV_RS08925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBEV_RS08935	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBEV_RS08940	COG0195	Participates in both transcription termination and antitermination
BBEV_RS08945	COG0779	Required for maturation of 30S ribosomal subunits
BBEV_RS08950	COG2176	DNA-directed DNA polymerase activity
BBEV_RS08955	COG0442	prolyl-tRNA aminoacylation
BBEV_RS08960	COG0750	zinc metalloprotease
BBEV_RS08970	COG4589	Belongs to the CDS family
BBEV_RS08975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBEV_RS08980	COG0233	cytoplasmic translational termination
BBEV_RS08985	COG0528	UMP kinase activity
BBEV_RS08990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBEV_RS08995	COG0052	Belongs to the universal ribosomal protein uS2 family
BBEV_RS09015	COG1191	sigma factor activity
BBEV_RS09025	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BBEV_RS09030	COG1776	CheC inhibitor of MCP methylation
BBEV_RS09035	COG0835	chemotaxis
BBEV_RS09040	COG2198	Histidine kinase
BBEV_RS09040	COG0643	Histidine kinase
BBEV_RS09045	COG2201	protein-glutamate methylesterase activity
BBEV_RS09050	COG0455	bacterial-type flagellum organization
BBEV_RS09055	COG1419	protein localization to endoplasmic reticulum
BBEV_RS09060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBEV_RS09065	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBEV_RS09070	COG1684	flagellar biosynthetic protein fliR
BBEV_RS09075	COG1987	bacterial-type flagellum assembly
BBEV_RS09080	COG1338	Plays a role in the flagellum-specific transport system
BBEV_RS09085	COG3190	flagellar
BBEV_RS09090	COG2201	protein-glutamate methylesterase activity
BBEV_RS09095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBEV_RS09095	COG1776	CheC inhibitor of MCP methylation
BBEV_RS09100	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBEV_RS09110	COG1582	Flagellar protein (FlbD)
BBEV_RS09125	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BBEV_RS09145	COG1157	protein secretion by the type III secretion system
BBEV_RS09150	COG1317	bacterial-type flagellum organization
BBEV_RS09155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBEV_RS09160	COG1766	The M ring may be actively involved in energy transduction
BBEV_RS09165	COG1677	Flagellar hook-basal body complex protein FliE
BBEV_RS09170	COG1558	bacterial-type flagellum-dependent cell motility
BBEV_RS09175	COG1815	bacterial-type flagellum-dependent cell motility
BBEV_RS09180	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBEV_RS09185	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBEV_RS09190	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBEV_RS09195	COG4974	Belongs to the 'phage' integrase family
BBEV_RS09200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBEV_RS09205	COG0758	DNA mediated transformation
BBEV_RS09210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBEV_RS09215	COG0045	succinate-CoA ligase (ADP-forming) activity
BBEV_RS09220	COG2257	FlhB HrpN YscU SpaS Family
BBEV_RS09230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBEV_RS09245	COG0335	large ribosomal subunit rRNA binding
BBEV_RS09250	COG0336	Belongs to the RNA methyltransferase TrmD family
BBEV_RS09255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBEV_RS09265	COG1837	Belongs to the UPF0109 family
BBEV_RS09270	COG0228	four-way junction DNA binding
BBEV_RS09275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBEV_RS09280	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BBEV_RS09285	COG0552	protein localization to endoplasmic reticulum
BBEV_RS09290	COG1196	nuclear chromosome segregation
BBEV_RS09295	COG4840	Belongs to the UPF0435 family
BBEV_RS09305	COG0571	ribonuclease III activity
BBEV_RS09310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBEV_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS09320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBEV_RS09325	COG0416	fatty acid biosynthetic process
BBEV_RS09330	COG1349	DNA-binding transcription factor activity
BBEV_RS09335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBEV_RS09340	COG1760	l-serine dehydratase
BBEV_RS09345	COG1760	l-serine dehydratase
BBEV_RS09350	COG1307	EDD domain protein, DegV family
BBEV_RS09355	COG1461	Dihydroxyacetone kinase
BBEV_RS09360	COG1302	Protein conserved in bacteria
BBEV_RS09365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBEV_RS09370	COG1564	THIamine pyrophosphokinase
BBEV_RS09375	COG3859	Proton-coupled thiamine transporter YuaJ
BBEV_RS09380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBEV_RS09385	COG1162	GTPase activity
BBEV_RS09390	COG0515	serine threonine protein kinase
BBEV_RS09390	COG2815	serine threonine protein kinase
BBEV_RS09395	COG0631	protein serine/threonine phosphatase activity
BBEV_RS09400	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBEV_RS09400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBEV_RS09405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBEV_RS09410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBEV_RS09415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBEV_RS09420	COG1758	RNA polymerase activity
BBEV_RS09425	COG0194	GDP metabolic process
BBEV_RS09430	COG2052	Domain of unknown function (DUF370)
BBEV_RS09435	COG1561	YicC-like family, N-terminal region
BBEV_RS09445	COG1132	(ABC) transporter
BBEV_RS09450	COG1132	(ABC) transporter
BBEV_RS09465	COG0167	dihydroorotate dehydrogenase activity
BBEV_RS09475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBEV_RS09480	COG0505	Belongs to the CarA family
BBEV_RS09485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBEV_RS09490	COG0540	Belongs to the ATCase OTCase family
BBEV_RS09500	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBEV_RS09505	COG0564	pseudouridine synthase activity
BBEV_RS09510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBEV_RS09515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBEV_RS09520	COG3599	regulation of cell shape
BBEV_RS09525	COG2302	S4 RNA-binding domain
BBEV_RS09530	COG0762	integral membrane protein
BBEV_RS09535	COG1799	cell septum assembly
BBEV_RS09540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBEV_RS09545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBEV_RS09550	COG0849	cell division
BBEV_RS09555	COG3856	small basic protein
BBEV_RS09560	COG3879	Bacterial protein of unknown function (DUF881)
BBEV_RS09565	COG3879	Bacterial protein of unknown function (DUF881)
BBEV_RS09570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BBEV_RS09575	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBEV_RS09580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBEV_RS09585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBEV_RS09590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBEV_RS09595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBEV_RS09600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBEV_RS09605	COG0768	penicillin binding
BBEV_RS09615	COG0275	rRNA processing
BBEV_RS09620	COG2001	Belongs to the MraZ family
BBEV_RS09625	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BBEV_RS09635	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBEV_RS09640	COG0454	-acetyltransferase
BBEV_RS09645	COG1024	Enoyl-CoA hydratase
BBEV_RS09650	COG1399	metal-binding, possibly nucleic acid-binding protein
BBEV_RS09655	COG1323	Belongs to the UPF0348 family
BBEV_RS09660	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBEV_RS09665	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBEV_RS09670	COG0742	ribosomal rna small subunit methyltransferase
BBEV_RS09675	COG4471	UPF0298 protein
BBEV_RS09680	COG3679	Belongs to the UPF0342 family
BBEV_RS09685	COG2340	Cysteine-rich secretory protein family
BBEV_RS09695	COG0628	permease
BBEV_RS09705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BBEV_RS09710	COG1845	cytochrome c oxidase, subunit III
BBEV_RS09715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BBEV_RS09720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BBEV_RS09720	COG2010	Cytochrome c
BBEV_RS09725	COG0109	protoheme IX farnesyltransferase activity
BBEV_RS09730	COG1612	heme a metabolic process
BBEV_RS09735	COG0783	Belongs to the Dps family
BBEV_RS09740	COG4838	Belongs to the UPF0358 family
BBEV_RS09745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BBEV_RS09755	COG4896	Protein conserved in bacteria
BBEV_RS09770	COG2801	Transposase and inactivated derivatives
BBEV_RS09775	COG0483	inositol monophosphate 1-phosphatase activity
BBEV_RS09785	COG4493	Belongs to the UPF0637 family
BBEV_RS09790	COG4476	Belongs to the UPF0223 family
BBEV_RS09795	COG1982	Orn Lys Arg decarboxylase major
BBEV_RS09825	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_RS09830	COG0022	dehydrogenase e1 component
BBEV_RS09850	COG0242	peptide deformylase activity
BBEV_RS09855	COG5503	Protein of unknown function (DUF1447)
BBEV_RS09860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBEV_RS09865	COG0569	domain protein
BBEV_RS09870	COG0668	transmembrane transport
BBEV_RS09875	COG1473	amidohydrolase
BBEV_RS09880	COG2171	N-acyltransferase activity
BBEV_RS09895	COG0668	transmembrane transport
BBEV_RS09900	COG0569	domain protein
BBEV_RS09905	COG1136	(ABC) transporter
BBEV_RS09910	COG0778	Nitroreductase
BBEV_RS09915	COG1854	S-ribosylhomocysteine lyase activity
BBEV_RS09930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBEV_RS09940	COG2151	metal-sulfur cluster biosynthetic enzyme
BBEV_RS09950	COG0656	L-ascorbic acid biosynthetic process
BBEV_RS09955	COG0534	Mate efflux family protein
BBEV_RS09975	COG1595	DNA-templated transcription, initiation
BBEV_RS09980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_RS09985	COG2224	Isocitrate lyase
BBEV_RS09990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BBEV_RS10000	COG0493	'glutamate synthase
BBEV_RS10005	COG0069	glutamate synthase activity
BBEV_RS10005	COG0067	glutamate synthase
BBEV_RS10005	COG0070	glutamate synthase
BBEV_RS10015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_RS10015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBEV_RS10020	COG5001	Diguanylate cyclase
BBEV_RS10020	COG3300	MHYT domain
BBEV_RS10030	COG0535	radical SAM domain protein
BBEV_RS10045	COG0739	heme binding
BBEV_RS10070	COG0564	pseudouridine synthase activity
BBEV_RS10075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBEV_RS10080	COG2357	RelA SpoT domain protein
BBEV_RS10090	COG0741	lytic transglycosylase activity
BBEV_RS10090	COG0739	heme binding
BBEV_RS10090	COG1196	nuclear chromosome segregation
BBEV_RS10095	COG2346	COG2346, Truncated hemoglobins
BBEV_RS10100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BBEV_RS10105	COG1164	Oligoendopeptidase f
BBEV_RS10115	COG4862	establishment of competence for transformation
BBEV_RS10120	COG1393	Belongs to the ArsC family
BBEV_RS10125	COG0456	acetyltransferase
BBEV_RS10135	COG1418	mRNA catabolic process
BBEV_RS10140	COG0530	calcium, potassium:sodium antiporter activity
BBEV_RS10145	COG0180	Tryptophanyl-tRNA synthetase
BBEV_RS10150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_RS10160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBEV_RS10165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBEV_RS10175	COG1744	ABC transporter substrate-binding protein PnrA-like
BBEV_RS10180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_RS10185	COG4841	protein insertion into membrane
BBEV_RS10190	COG0303	'Molybdopterin
BBEV_RS10195	COG1763	Mo-molybdopterin cofactor biosynthetic process
BBEV_RS10200	COG0314	molybdopterin synthase activity
BBEV_RS10210	COG1999	signal sequence binding
BBEV_RS10215	COG3336	cytochrome c oxidase
BBEV_RS10220	COG0561	phosphatase activity
BBEV_RS10235	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BBEV_RS10250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_RS10265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS10270	COG0628	permease
BBEV_RS10275	COG1609	Transcriptional regulator
BBEV_RS10280	COG3833	ABC-type maltose transport systems, permease component
BBEV_RS10285	COG1175	transmembrane transport
BBEV_RS10300	COG2207	Transcriptional regulator
BBEV_RS10300	COG0662	Cupin 2, conserved barrel domain protein
BBEV_RS10330	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_RS10335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_RS10350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS10355	COG0628	permease
BBEV_RS10360	COG1609	Transcriptional regulator
BBEV_RS10370	COG3833	ABC-type maltose transport systems, permease component
BBEV_RS10375	COG1175	transmembrane transport
BBEV_RS10385	COG0662	Cupin 2, conserved barrel domain protein
BBEV_RS10385	COG2207	Transcriptional regulator
BBEV_RS10390	COG0534	Mate efflux family protein
BBEV_RS10395	COG2358	TRAP transporter, solute receptor (TAXI family
BBEV_RS10405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBEV_RS10410	COG1509	lysine 2,3-aminomutase activity
BBEV_RS10425	COG1032	radical SAM domain protein
BBEV_RS10430	COG2249	NAD(P)H dehydrogenase (quinone) activity
BBEV_RS10435	COG5001	Diguanylate cyclase
BBEV_RS10435	COG3300	MHYT domain
BBEV_RS10440	COG2154	pterin-4-alpha-carbinolamine dehydratase
BBEV_RS10450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBEV_RS10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_RS10470	COG1309	transcriptional regulator
BBEV_RS10485	COG1079	Belongs to the binding-protein-dependent transport system permease family
BBEV_RS10490	COG4603	Belongs to the binding-protein-dependent transport system permease family
BBEV_RS10495	COG3845	ABC transporter
BBEV_RS10500	COG1744	ABC transporter substrate-binding protein PnrA-like
BBEV_RS10505	COG3192	ethanolamine utilization protein
BBEV_RS10510	COG1489	DNA binding
BBEV_RS10530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBEV_RS10570	COG0217	transcriptional regulatory protein
BBEV_RS10595	COG1335	isochorismatase
BBEV_RS10600	COG1510	regulation of RNA biosynthetic process
BBEV_RS10630	COG5278	phosphoserine phosphatase activity
BBEV_RS10630	COG0840	transmembrane signaling receptor activity
BBEV_RS10650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBEV_RS10655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBEV_RS10660	COG1116	anion transmembrane transporter activity
BBEV_RS10675	COG0584	glycerophosphoryl diester phosphodiesterase
BBEV_RS10680	COG2357	RelA SpoT domain protein
BBEV_RS10705	COG3381	protein complex oligomerization
BBEV_RS10710	COG0493	'glutamate synthase
BBEV_RS10710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBEV_RS10715	COG0243	molybdopterin cofactor binding
BBEV_RS10725	COG4585	Histidine kinase
BBEV_RS10735	COG2720	vancomycin resistance protein
BBEV_RS10740	COG1461	Dihydroxyacetone kinase
BBEV_RS10755	COG2116	formate transmembrane transporter activity
BBEV_RS10790	COG0583	DNA-binding transcription factor activity
BBEV_RS10820	COG0154	amidase activity
BBEV_RS10825	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS10855	COG0326	Molecular chaperone. Has ATPase activity
BBEV_RS10885	COG1104	cysteine desulfurase activity
BBEV_RS10895	COG0419	ATPase involved in DNA repair
BBEV_RS10940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBEV_RS10950	COG1360	Flagellar Motor Protein
BBEV_RS10990	COG3829	transcription factor binding
BBEV_RS10990	COG3290	protein histidine kinase activity
BBEV_RS11000	COG0840	transmembrane signaling receptor activity
BBEV_RS11005	COG0124	histidyl-tRNA synthetase
BBEV_RS11010	COG1349	DNA-binding transcription factor activity
BBEV_RS11015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBEV_RS11020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BBEV_RS11025	COG0246	Mannitol dehydrogenase
BBEV_RS11035	COG2213	PTS system mannitol-specific
BBEV_RS11045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBEV_RS11050	COG2048	Heterodisulfide reductase, subunit B
BBEV_RS11055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBEV_RS11060	COG1053	succinate dehydrogenase
BBEV_RS11070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BBEV_RS11070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BBEV_RS11075	COG0471	metal ion transport
BBEV_RS11080	COG4565	transcriptional regulatory protein
BBEV_RS11085	COG3290	protein histidine kinase activity
BBEV_RS11095	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS11100	COG0243	molybdopterin cofactor binding
BBEV_RS11105	COG3381	protein complex oligomerization
BBEV_RS11110	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS11115	COG0243	molybdopterin cofactor binding
BBEV_RS11120	COG2508	Transcriptional regulator
BBEV_RS11135	COG0579	oxidoreductase
BBEV_RS11150	COG1309	transcriptional regulator
BBEV_RS11185	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBEV_RS11190	COG2311	Membrane
BBEV_RS11220	COG1131	(ABC) transporter
BBEV_RS11235	COG0450	alkyl hydroperoxide reductase
BBEV_RS11250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBEV_RS11255	COG2022	thiamine diphosphate biosynthetic process
BBEV_RS11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBEV_RS11270	COG0352	thiamine-phosphate diphosphorylase activity
BBEV_RS11275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBEV_RS11285	COG0419	ATPase involved in DNA repair
BBEV_RS11290	COG0420	3'-5' exonuclease activity
BBEV_RS11295	COG4221	oxidoreductase activity
BBEV_RS11305	COG3835	regulator
BBEV_RS11310	COG0243	molybdopterin cofactor binding
BBEV_RS11325	COG3302	dmso reductase anchor subunit
BBEV_RS11330	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS11335	COG0243	molybdopterin cofactor binding
BBEV_RS11465	COG0735	belongs to the Fur family
BBEV_RS11490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBEV_RS11495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBEV_RS11500	COG0067	glutamate synthase
BBEV_RS11500	COG0069	glutamate synthase activity
BBEV_RS11500	COG0070	glutamate synthase
BBEV_RS11505	COG4129	membrane
BBEV_RS11515	COG1132	(ABC) transporter
BBEV_RS11520	COG3557	Belongs to the UPF0374 family
BBEV_RS11535	COG1215	transferase activity, transferring glycosyl groups
BBEV_RS11550	COG2059	Chromate
BBEV_RS11555	COG2059	Chromate
BBEV_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS11570	COG1194	a g-specific adenine glycosylase
BBEV_RS11575	COG1988	membrane-bound metal-dependent
BBEV_RS11590	COG2137	regulation of response to DNA damage stimulus
BBEV_RS11595	COG1090	epimerase
BBEV_RS11605	COG2188	Transcriptional regulator
BBEV_RS11625	COG0492	ferredoxin-NADP+ reductase activity
BBEV_RS11650	COG0601	transmembrane transport
BBEV_RS11665	COG1151	hydroxylamine reductase activity
BBEV_RS11685	COG0298	carbon dioxide binding
BBEV_RS11690	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BBEV_RS11695	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBEV_RS11700	COG0375	protein maturation
BBEV_RS11715	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BBEV_RS11730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBEV_RS11755	COG0535	radical SAM domain protein
BBEV_RS11760	COG0534	Mate efflux family protein
BBEV_RS11765	COG0477	Major facilitator Superfamily
BBEV_RS11800	COG1254	Belongs to the acylphosphatase family
BBEV_RS11810	COG0415	Belongs to the DNA photolyase family
BBEV_RS11820	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS11830	COG2226	methyltransferase
BBEV_RS11835	COG0288	reversible hydration of carbon dioxide
BBEV_RS11840	COG0425	Belongs to the sulfur carrier protein TusA family
BBEV_RS11845	COG0425	Belongs to the sulfur carrier protein TusA family
BBEV_RS11845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS11855	COG0628	permease
BBEV_RS11870	COG0488	(ABC) transporter
BBEV_RS11880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBEV_RS11885	COG0400	carboxylic ester hydrolase activity
BBEV_RS11890	COG0514	ATP-dependent DNA helicase (RecQ)
BBEV_RS11895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_RS11900	COG1937	Protein conserved in bacteria
BBEV_RS11905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BBEV_RS11910	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BBEV_RS11925	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBEV_RS11930	COG1132	(ABC) transporter
BBEV_RS11935	COG1132	(ABC) transporter
BBEV_RS11940	COG1929	Belongs to the glycerate kinase type-1 family
BBEV_RS11945	COG0366	Alpha amylase catalytic
BBEV_RS11950	COG2962	Rard protein
BBEV_RS11960	COG2801	Transposase and inactivated derivatives
BBEV_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS11985	COG4895	conserved protein (DUF2196)
BBEV_RS11990	COG5001	Diguanylate cyclase
BBEV_RS11990	COG3447	MASE1 domain protein
BBEV_RS11990	COG5002	protein histidine kinase activity
BBEV_RS12005	COG1554	hydrolase, family 65, central catalytic
BBEV_RS12010	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS12015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBEV_RS12020	COG4605	iron ion homeostasis
BBEV_RS12025	COG4604	ABC transporter, ATP-binding protein
BBEV_RS12030	COG4607	ABC-type enterochelin transport system periplasmic component
BBEV_RS12035	COG0194	GDP metabolic process
BBEV_RS12045	COG1070	Carbohydrate kinase
BBEV_RS12050	COG2115	Belongs to the xylose isomerase family
BBEV_RS12055	COG1940	carbohydrate kinase activity
BBEV_RS12060	COG1917	Cupin 2, conserved barrel domain protein
BBEV_RS12060	COG2207	Transcriptional regulator
BBEV_RS12065	COG2972	Histidine kinase
BBEV_RS12070	COG4753	response regulator
BBEV_RS12070	COG2207	Transcriptional regulator
BBEV_RS12075	COG1653	transport
BBEV_RS12090	COG3507	Belongs to the glycosyl hydrolase 43 family
BBEV_RS12095	COG5578	integral membrane protein
BBEV_RS12105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBEV_RS12120	COG5487	UPF0391 membrane protein
BBEV_RS12125	COG5487	UPF0391 membrane protein
BBEV_RS12135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBEV_RS12140	COG3584	3D domain protein
BBEV_RS12140	COG1388	LysM domain
BBEV_RS12155	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBEV_RS12160	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBEV_RS12160	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBEV_RS12170	COG3386	PFAM SMP-30 Gluconolaconase
BBEV_RS12175	COG2814	Major facilitator Superfamily
BBEV_RS12190	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBEV_RS12195	COG2755	lipolytic protein G-D-S-L family
BBEV_RS12195	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBEV_RS12205	COG2391	methyltransferase activity
BBEV_RS12220	COG2897	thiosulfate sulfurtransferase activity
BBEV_RS12230	COG0840	transmembrane signaling receptor activity
BBEV_RS12240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBEV_RS12245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBEV_RS12260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBEV_RS12285	COG1940	carbohydrate kinase activity
BBEV_RS12295	COG3973	AAA domain
BBEV_RS12300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBEV_RS12320	COG4372	Transposase
BBEV_RS12340	COG1309	transcriptional regulator
BBEV_RS12375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_RS12400	COG3850	Histidine kinase
BBEV_RS12405	COG1960	acyl-CoA dehydrogenase activity
BBEV_RS12435	COG1309	transcriptional regulator
BBEV_RS12440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBEV_RS12445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBEV_RS12450	COG1120	ATPase activity
BBEV_RS12455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BBEV_RS12465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBEV_RS12470	COG0406	alpha-ribazole phosphatase activity
BBEV_RS12485	COG2217	Heavy metal translocating P-type atpase
BBEV_RS12525	COG1733	regulation of RNA biosynthetic process
BBEV_RS12535	COG3842	ATPase activity
BBEV_RS12550	COG1910	domain protein
BBEV_RS12555	COG2346	COG2346, Truncated hemoglobins
BBEV_RS12560	COG2070	2-Nitropropane dioxygenase
BBEV_RS12570	COG0667	Aldo Keto reductase
BBEV_RS12575	COG0561	phosphatase activity
BBEV_RS12585	COG2514	catechol 2,3-dioxygenase activity
BBEV_RS12590	COG1966	Carbon starvation protein
BBEV_RS12595	COG3279	Response regulator of the LytR AlgR family
BBEV_RS12600	COG3275	phosphorelay sensor kinase activity
BBEV_RS12680	COG0456	acetyltransferase
BBEV_RS12740	COG3177	Filamentation induced by cAMP protein fic
BBEV_RS12765	COG4372	Transposase
BBEV_RS12790	COG1404	Belongs to the peptidase S8 family
BBEV_RS12815	COG4372	Transposase
BBEV_RS12820	COG3547	Transposase (IS116 IS110 IS902 family)
BBEV_RS12860	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBEV_RS12880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBEV_RS12900	COG0640	Transcriptional regulator
BBEV_RS12910	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBEV_RS12925	COG1597	lipid kinase activity
BBEV_RS12935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBEV_RS12940	COG0154	amidase activity
BBEV_RS12955	COG4851	CamS sex pheromone cAM373 precursor
BBEV_RS12960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBEV_RS12965	COG0210	DNA helicase
BBEV_RS12970	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BBEV_RS12975	COG0840	transmembrane signaling receptor activity
BBEV_RS12980	COG0494	nUDIX hydrolase
BBEV_RS13005	COG2124	cytochrome p450
BBEV_RS13015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBEV_RS13025	COG0523	cobalamin synthesis protein
BBEV_RS13040	COG0400	carboxylic ester hydrolase activity
BBEV_RS13045	COG0346	lactoylglutathione lyase activity
BBEV_RS13055	COG4496	protein, YerC YecD
BBEV_RS13060	COG1470	cell adhesion involved in biofilm formation
BBEV_RS13065	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBEV_RS13075	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBEV_RS13080	COG0405	Gamma-glutamyltransferase
BBEV_RS13085	COG0492	ferredoxin-NADP+ reductase activity
BBEV_RS13090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBEV_RS13100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BBEV_RS13110	COG3639	organic phosphonate transmembrane transporter activity
BBEV_RS13140	COG0110	maltose O-acetyltransferase activity
BBEV_RS13145	COG0517	IMP dehydrogenase activity
BBEV_RS13150	COG0151	Belongs to the GarS family
BBEV_RS13155	COG0138	bifunctional purine biosynthesis protein purh
BBEV_RS13160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBEV_RS13170	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBEV_RS13175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBEV_RS13180	COG0047	phosphoribosylformylglycinamidine synthase activity
BBEV_RS13185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBEV_RS13190	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BBEV_RS13195	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBEV_RS13200	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBEV_RS13205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBEV_RS13220	COG0542	response to heat
BBEV_RS13230	COG5002	protein histidine kinase activity
BBEV_RS13245	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBEV_RS13255	COG2252	PERMEase
BBEV_RS13260	COG0519	Catalyzes the synthesis of GMP from XMP
BBEV_RS13260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBEV_RS13265	COG1305	Transglutaminase-like
BBEV_RS13270	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BBEV_RS13275	COG0714	Associated with various cellular activities
BBEV_RS13290	COG0778	Nitroreductase
BBEV_RS13295	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_RS13300	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBEV_RS13305	COG4988	ABC transporter
BBEV_RS13320	COG0584	glycerophosphoryl diester phosphodiesterase
BBEV_RS13350	COG1132	(ABC) transporter
BBEV_RS13355	COG0745	RESPONSE REGULATOR receiver
BBEV_RS13360	COG3850	Histidine kinase
BBEV_RS13360	COG5002	protein histidine kinase activity
BBEV_RS13385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_RS13385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS13390	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BBEV_RS13405	COG1454	alcohol dehydrogenase
BBEV_RS13410	COG2133	pyrroloquinoline quinone binding
BBEV_RS13415	COG1827	regulation of RNA biosynthetic process
BBEV_RS13420	COG1104	cysteine desulfurase activity
BBEV_RS13425	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBEV_RS13430	COG0157	Belongs to the NadC ModD family
BBEV_RS13435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBEV_RS13440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBEV_RS13445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBEV_RS13450	COG1215	transferase activity, transferring glycosyl groups
BBEV_RS13475	COG0437	4 iron, 4 sulfur cluster binding
BBEV_RS13485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BBEV_RS13495	COG2351	hydroxyisourate hydrolase activity
BBEV_RS13505	COG3648	Uricase
BBEV_RS13505	COG3195	allantoin biosynthetic process
BBEV_RS13510	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_RS13515	COG0746	molybdenum cofactor guanylyltransferase activity
BBEV_RS13520	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBEV_RS13525	COG2080	2 iron, 2 sulfur cluster binding
BBEV_RS13530	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBEV_RS13535	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BBEV_RS13540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBEV_RS13545	COG0154	amidase activity
BBEV_RS13560	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_RS13565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBEV_RS13580	COG0402	S-adenosylhomocysteine deaminase activity
BBEV_RS13585	COG2508	Transcriptional regulator
BBEV_RS13595	COG0737	Belongs to the 5'-nucleotidase family
BBEV_RS13615	COG3437	response regulator, receiver
BBEV_RS13615	COG2770	Histidine kinase
BBEV_RS13625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BBEV_RS13650	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BBEV_RS13655	COG1053	succinate dehydrogenase
BBEV_RS13660	COG2009	succinate dehydrogenase
BBEV_RS13665	COG1027	Aspartate ammonia-lyase
BBEV_RS13680	COG4191	Histidine kinase
BBEV_RS13685	COG0784	Response regulator, receiver
BBEV_RS13700	COG0745	RESPONSE REGULATOR receiver
BBEV_RS13700	COG2972	Histidine kinase
BBEV_RS13715	COG3284	Transcriptional regulator
BBEV_RS13720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBEV_RS13725	COG0022	dehydrogenase e1 component
BBEV_RS13730	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBEV_RS13735	COG1063	alcohol dehydrogenase
BBEV_RS13740	COG0415	Belongs to the DNA photolyase family
BBEV_RS13750	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBEV_RS13770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBEV_RS13785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBEV_RS13790	COG0783	Belongs to the Dps family
BBEV_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS13805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBEV_RS13820	COG0471	metal ion transport
BBEV_RS13855	COG0702	epimerase
BBEV_RS13860	COG0346	lactoylglutathione lyase activity
BBEV_RS13865	COG0667	Aldo Keto reductase
BBEV_RS13870	COG0459	protein refolding
BBEV_RS13875	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBEV_RS13880	COG1266	CAAX protease self-immunity
BBEV_RS13895	COG0243	molybdopterin cofactor binding
BBEV_RS13930	COG2814	Major facilitator Superfamily
BBEV_RS13935	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BBEV_RS13945	COG0488	(ABC) transporter
BBEV_RS13950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBEV_RS13955	COG0456	acetyltransferase
BBEV_RS13960	COG1214	PFAM Peptidase M22, glycoprotease
BBEV_RS13965	COG0802	atpase or kinase
BBEV_RS13970	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BBEV_RS13975	COG0626	cystathionine gamma-synthase activity
BBEV_RS13980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BBEV_RS13985	COG4988	ABC transporter
BBEV_RS13990	COG1294	oxidase, subunit
BBEV_RS13995	COG1271	oxidase subunit
BBEV_RS14060	COG3091	SprT-like family
BBEV_RS14065	COG2183	response to ionizing radiation
BBEV_RS14075	COG1191	sigma factor activity
BBEV_RS14080	COG2172	sigma factor antagonist activity
BBEV_RS14085	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_RS14090	COG2208	phosphoserine phosphatase activity
BBEV_RS14095	COG2172	sigma factor antagonist activity
BBEV_RS14100	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_RS14105	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_RS14110	COG2337	Toxic component of a toxin-antitoxin (TA) module
BBEV_RS14120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBEV_RS14125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBEV_RS14125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBEV_RS14135	COG0705	Rhomboid family
BBEV_RS14140	COG1178	ABC-type Fe3 transport system permease component
BBEV_RS14150	COG3842	ATPase activity
BBEV_RS14160	COG0506	proline dehydrogenase activity
BBEV_RS14165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBEV_RS14170	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS14175	COG3829	transcription factor binding
BBEV_RS14190	COG1595	DNA-templated transcription, initiation
BBEV_RS14205	COG5001	Diguanylate cyclase
BBEV_RS14205	COG3300	MHYT domain
BBEV_RS14225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_RS14230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBEV_RS14235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBEV_RS14240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBEV_RS14240	COG1263	PTS System
BBEV_RS14245	COG1609	Transcriptional regulator
BBEV_RS14250	COG1278	Cold shock
BBEV_RS14260	COG0659	secondary active sulfate transmembrane transporter activity
BBEV_RS14265	COG0589	response to stress
BBEV_RS14270	COG2226	methyltransferase
BBEV_RS14275	COG0534	Mate efflux family protein
BBEV_RS14285	COG2202	Pas domain
BBEV_RS14285	COG1366	Belongs to the anti-sigma-factor antagonist family
BBEV_RS14290	COG0640	Transcriptional regulator
BBEV_RS14300	COG2239	Acts as a magnesium transporter
BBEV_RS14315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBEV_RS14320	COG0765	amino acid transport
BBEV_RS14335	COG1227	inorganic diphosphatase activity
BBEV_RS14340	COG1410	methionine synthase
BBEV_RS14340	COG0646	methionine synthase
BBEV_RS14350	COG0626	cystathionine gamma-synthase activity
BBEV_RS14355	COG0626	cystathionine gamma-synthase activity
BBEV_RS14375	COG1247	-acetyltransferase
BBEV_RS14380	COG0477	Major facilitator Superfamily
BBEV_RS14385	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BBEV_RS14390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBEV_RS14420	COG1131	(ABC) transporter
BBEV_RS14425	COG2188	Transcriptional regulator
BBEV_RS14440	COG0398	Pfam SNARE associated Golgi protein
BBEV_RS14455	COG0604	alcohol dehydrogenase
BBEV_RS14460	COG2860	membrane
BBEV_RS14475	COG1272	protein, Hemolysin III
BBEV_RS14480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBEV_RS14495	COG1234	tRNA 3'-trailer cleavage
BBEV_RS14500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BBEV_RS14510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBEV_RS14510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS14530	COG4989	oxidoreductase activity
BBEV_RS14535	COG0501	Belongs to the peptidase M48B family
BBEV_RS14550	COG0655	NAD(P)H dehydrogenase (quinone) activity
BBEV_RS14560	COG1846	Transcriptional regulator
BBEV_RS14565	COG0346	lactoylglutathione lyase activity
BBEV_RS14570	COG0398	Pfam SNARE associated Golgi protein
BBEV_RS14585	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BBEV_RS14590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBEV_RS14595	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBEV_RS14605	COG1609	Transcriptional regulator
BBEV_RS14625	COG1653	transport
BBEV_RS14635	COG1704	LemA family
BBEV_RS14640	COG0501	Belongs to the peptidase M48B family
BBEV_RS14645	COG1846	Transcriptional regulator
BBEV_RS14670	COG0739	heme binding
BBEV_RS14670	COG0741	lytic transglycosylase activity
BBEV_RS14670	COG1196	nuclear chromosome segregation
BBEV_RS14675	COG0745	RESPONSE REGULATOR receiver
BBEV_RS14680	COG0791	NLP P60 protein
BBEV_RS14680	COG1388	LysM domain
BBEV_RS14685	COG1874	Beta-galactosidase
BBEV_RS14695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBEV_RS14725	COG2135	peptidase activity
BBEV_RS14730	COG2746	aminoglycoside 3-N-acetyltransferase activity
BBEV_RS14745	COG2409	Drug exporters of the RND superfamily
BBEV_RS14755	COG0295	cytidine deaminase activity
BBEV_RS14785	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BBEV_RS14800	COG3711	transcriptional antiterminator
BBEV_RS14805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_RS14810	COG0246	Mannitol dehydrogenase
BBEV_RS14820	COG3173	Aminoglycoside phosphotransferase
BBEV_RS14835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBEV_RS14840	COG0427	acetyl-CoA hydrolase
BBEV_RS14845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBEV_RS14850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBEV_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
BBEV_RS14875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBEV_RS14880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBEV_RS14885	COG4856	YbbR-like protein
BBEV_RS14890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBEV_RS14895	COG5662	AntiSigma factor
BBEV_RS14900	COG1595	DNA-templated transcription, initiation
BBEV_RS14930	COG2194	sulfuric ester hydrolase activity
BBEV_RS14935	COG0489	protein tyrosine kinase activity
BBEV_RS14940	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BBEV_RS14950	COG0667	Aldo Keto reductase
BBEV_RS14965	COG0726	polysaccharide deacetylase
BBEV_RS14970	COG1132	(ABC) transporter
BBEV_RS14975	COG1132	(ABC) transporter
BBEV_RS14995	COG1510	regulation of RNA biosynthetic process
BBEV_RS15000	COG0517	IMP dehydrogenase activity
BBEV_RS15000	COG4175	Glycine betaine
BBEV_RS15015	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BBEV_RS15035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBEV_RS15040	COG0709	Synthesizes selenophosphate from selenide and ATP
BBEV_RS15045	COG0371	Dehydrogenase
BBEV_RS15050	COG1609	Transcriptional regulator
BBEV_RS15055	COG2160	L-arabinose isomerase activity
BBEV_RS15060	COG1069	ribulokinase activity
BBEV_RS15070	COG1653	transport
BBEV_RS15075	COG1175	transmembrane transport
BBEV_RS15080	COG0395	ABC-type sugar transport system, permease component
BBEV_RS15090	COG3534	alpha-L-arabinofuranosidase
BBEV_RS15100	COG4149	molybdate abc transporter
BBEV_RS15105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BBEV_RS15125	COG0395	ABC-type sugar transport system, permease component
BBEV_RS15135	COG1653	transport
BBEV_RS15140	COG5578	integral membrane protein
BBEV_RS15145	COG1609	Transcriptional regulator
BBEV_RS15155	COG1940	carbohydrate kinase activity
BBEV_RS15165	COG1595	DNA-templated transcription, initiation
BBEV_RS15175	COG5002	protein histidine kinase activity
BBEV_RS15195	COG1737	Transcriptional regulator
BBEV_RS15200	COG1653	transport
BBEV_RS15205	COG1486	melibiose metabolic process
BBEV_RS15210	COG1714	RDD family
BBEV_RS15215	COG2814	Major facilitator Superfamily
BBEV_RS15250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBEV_RS15260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBEV_RS15265	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBEV_RS15270	COG0716	FMN binding
BBEV_RS15275	COG1328	CTP reductase activity
BBEV_RS15290	COG0395	ABC-type sugar transport system, permease component
BBEV_RS15300	COG1653	transport
BBEV_RS15310	COG1609	Transcriptional regulator
BBEV_RS15315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBEV_RS15320	COG2267	carboxylic ester hydrolase activity
BBEV_RS15345	COG4585	Histidine kinase
BBEV_RS15350	COG2197	response regulator
BBEV_RS15365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBEV_RS15370	COG0386	Belongs to the glutathione peroxidase family
BBEV_RS15405	COG0673	inositol 2-dehydrogenase activity
BBEV_RS15410	COG1082	Xylose isomerase domain protein TIM barrel
BBEV_RS15415	COG0673	inositol 2-dehydrogenase activity
BBEV_RS15435	COG3976	FMN-binding domain protein
BBEV_RS15435	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BBEV_RS15440	COG0574	Belongs to the PEP-utilizing enzyme family
BBEV_RS15440	COG3848	Pyruvate phosphate dikinase
BBEV_RS15445	COG1309	transcriptional regulator
BBEV_RS15450	COG5001	Diguanylate cyclase
BBEV_RS15450	COG3447	MASE1 domain protein
BBEV_RS15450	COG5002	protein histidine kinase activity
BBEV_RS15460	COG1595	DNA-templated transcription, initiation
BBEV_RS15475	COG2226	methyltransferase
BBEV_RS15480	COG1595	DNA-templated transcription, initiation
BBEV_RS15495	COG1131	(ABC) transporter
BBEV_RS15535	COG0596	Alpha beta hydrolase
BBEV_RS15540	COG0596	Alpha beta hydrolase
BBEV_RS15560	COG2188	Transcriptional regulator
BBEV_RS15565	COG3394	polysaccharide catabolic process
BBEV_RS15570	COG1486	melibiose metabolic process
BBEV_RS15575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBEV_RS15580	COG1447	Phosphotransferase system cellobiose-specific component IIA
BBEV_RS15585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBEV_RS15590	COG4372	Transposase
BBEV_RS15615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBEV_RS15625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBEV_RS15630	COG0577	efflux transmembrane transporter activity
BBEV_RS15630	COG1136	(ABC) transporter
BBEV_RS15710	COG3177	Filamentation induced by cAMP protein fic
BBEV_RS15725	COG1278	Cold shock
BBEV_RS15730	COG3654	unkown
BBEV_RS15755	COG0071	Belongs to the small heat shock protein (HSP20) family
BBEV_RS15815	COG3706	GGDEF domain
BBEV_RS15850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBEV_RS15860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BBEV_RS15885	COG2130	NADP-dependent
BBEV_RS15905	COG1247	-acetyltransferase
BBEV_RS15925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBEV_RS15925	COG3711	transcriptional antiterminator
BBEV_RS15940	COG3037	sugar-specific permease SgaT UlaA
BBEV_RS15945	COG0159	tryptophan synthase activity
BBEV_RS15960	COG1737	Transcriptional regulator
BBEV_RS15965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BBEV_RS15970	COG3876	Protein conserved in bacteria
BBEV_RS15975	COG1486	melibiose metabolic process
BBEV_RS15980	COG2971	BadF BadG BcrA BcrD
BBEV_RS15985	COG0395	ABC-type sugar transport system, permease component
BBEV_RS15990	COG1175	transmembrane transport
BBEV_RS16005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBEV_RS16020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBEV_RS16025	COG0363	glucosamine-6-phosphate deaminase activity
BBEV_RS16030	COG2188	Transcriptional regulator
BBEV_RS16035	COG4821	SIS domain
BBEV_RS16050	COG2239	Acts as a magnesium transporter
BBEV_RS16065	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS16070	COG1510	regulation of RNA biosynthetic process
BBEV_RS16080	COG3829	transcription factor binding
BBEV_RS16080	COG3290	protein histidine kinase activity
BBEV_RS16095	COG1012	belongs to the aldehyde dehydrogenase family
BBEV_RS16100	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BBEV_RS16105	COG0385	Bile acid
BBEV_RS16110	COG0415	Belongs to the DNA photolyase family
BBEV_RS16115	COG1876	peptidase activity
BBEV_RS16120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBEV_RS16125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBEV_RS16130	COG0367	asparagine synthase
BBEV_RS16135	COG1902	pentaerythritol trinitrate reductase activity
BBEV_RS16140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BBEV_RS16145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBEV_RS16150	COG0101	tRNA pseudouridine synthase activity
BBEV_RS16155	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBEV_RS16165	COG1122	ATPase activity
BBEV_RS16170	COG0203	ribosomal protein L17
BBEV_RS16175	COG0202	RNA polymerase activity
BBEV_RS16180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBEV_RS16185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBEV_RS16190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBEV_RS16195	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBEV_RS16200	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BBEV_RS16205	COG0024	Methionine aminopeptidase
BBEV_RS16210	COG0563	adenylate kinase activity
BBEV_RS16215	COG0200	Binds to the 23S rRNA
BBEV_RS16220	COG1841	ribosomal large subunit assembly
BBEV_RS16230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBEV_RS16235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBEV_RS16240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBEV_RS16245	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBEV_RS16250	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBEV_RS16255	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBEV_RS16260	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBEV_RS16265	COG0255	Belongs to the universal ribosomal protein uL29 family
BBEV_RS16270	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBEV_RS16275	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBEV_RS16280	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBEV_RS16285	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBEV_RS16290	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBEV_RS16295	COG0089	rRNA binding
BBEV_RS16300	COG0088	Forms part of the polypeptide exit tunnel
BBEV_RS16305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBEV_RS16310	COG0051	transcription antitermination factor activity, RNA binding
BBEV_RS16325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBEV_RS16330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBEV_RS16335	COG0049	tRNA binding
BBEV_RS16340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBEV_RS16345	COG1358	cellular component organization or biogenesis
BBEV_RS16350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBEV_RS16355	COG0085	RNA polymerase activity
BBEV_RS16365	COG2813	Specifically methylates the guanine in position
BBEV_RS16370	COG0222	ribosome binding
BBEV_RS16380	COG0081	regulation of translation
BBEV_RS16385	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBEV_RS16390	COG0250	Participates in transcription elongation, termination and antitermination
BBEV_RS16395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBEV_RS16405	COG1595	DNA-templated transcription, initiation
BBEV_RS16415	COG3688	RNA-binding protein containing a PIN domain
BBEV_RS16420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBEV_RS16430	COG0215	cysteine-tRNA ligase activity
BBEV_RS16435	COG1045	serine acetyltransferase
BBEV_RS16440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBEV_RS16450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBEV_RS16455	COG4956	integral membrane protein (PIN domain superfamily)
BBEV_RS16460	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BBEV_RS16465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBEV_RS16470	COG0542	response to heat
BBEV_RS16475	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BBEV_RS16480	COG3880	PFAM UvrB UvrC protein
BBEV_RS16490	COG1285	pathogenesis
BBEV_RS16495	COG0716	FMN binding
BBEV_RS16585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBEV_RS16590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBEV_RS16595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBEV_RS16600	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBEV_RS16605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBEV_RS16610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBEV_RS16615	COG0512	Glutamine amidotransferase of anthranilate synthase
BBEV_RS16620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBEV_RS16630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBEV_RS16635	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBEV_RS16640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBEV_RS16645	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBEV_RS16650	COG0037	tRNA processing
BBEV_RS16665	COG1098	S1 RNA binding domain
BBEV_RS16675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BBEV_RS16680	COG3956	TIGRFAM MazG family protein
BBEV_RS16685	COG2244	polysaccharide biosynthetic process
BBEV_RS16690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBEV_RS16695	COG0193	aminoacyl-tRNA hydrolase activity
BBEV_RS16700	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBEV_RS16705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBEV_RS16710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBEV_RS16715	COG2088	sporulation resulting in formation of a cellular spore
BBEV_RS16720	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBEV_RS16725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBEV_RS16730	COG4466	Protein conserved in bacteria
BBEV_RS16735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBEV_RS16740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BBEV_RS16745	COG3583	domain protein
BBEV_RS16745	COG3584	3D domain protein
BBEV_RS16750	COG0084	hydrolase, TatD family'
BBEV_RS16755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_RS16755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBEV_RS16760	COG2002	toxin-antitoxin pair type II binding
BBEV_RS16765	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBEV_RS16770	COG2827	Endonuclease containing a URI domain
BBEV_RS16775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBEV_RS16780	COG4467	Involved in initiation control of chromosome replication
BBEV_RS16785	COG1774	PSP1 C-terminal conserved region
BBEV_RS16790	COG0470	DNA polymerase III
BBEV_RS16795	COG3870	Protein conserved in bacteria
BBEV_RS16800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBEV_RS16805	COG1982	Orn Lys Arg decarboxylase major
BBEV_RS16825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBEV_RS16855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBEV_RS16860	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBEV_RS16865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBEV_RS16880	COG0590	tRNA wobble adenosine to inosine editing
BBEV_RS16885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBEV_RS16890	COG0601	transmembrane transport
BBEV_RS16900	COG4608	Belongs to the ABC transporter superfamily
BBEV_RS16905	COG0444	Belongs to the ABC transporter superfamily
BBEV_RS16920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBEV_RS16925	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BBEV_RS16940	COG0517	IMP dehydrogenase activity
BBEV_RS16940	COG0516	GMP reductase activity
BBEV_RS16975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBEV_RS16980	COG0187	DNA topoisomerase II activity