locus-tag	class	description
A7A70_RS00025	COG1388	LysM domain
A7A70_RS00025	COG3584	3D domain protein
A7A70_RS00030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A70_RS00030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A70_RS00030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A70_RS00035	COG1105	Belongs to the carbohydrate kinase PfkB family
A7A70_RS00040	COG1349	DNA-binding transcription factor activity
A7A70_RS00045	COG1979	alcohol dehydrogenase
A7A70_RS00050	COG2322	membrane
A7A70_RS00065	COG1113	amino acid transport
A7A70_RS00085	COG1408	metallophosphoesterase
A7A70_RS00090	COG2116	formate transmembrane transporter activity
A7A70_RS00105	COG2217	Heavy metal translocating P-type atpase
A7A70_RS00110	COG2608	mercury ion transmembrane transporter activity
A7A70_RS00115	COG1937	Protein conserved in bacteria
A7A70_RS00125	COG2819	hydrolase of the alpha beta superfamily
A7A70_RS00130	COG1120	ATPase activity
A7A70_RS00135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS00140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS00145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS00150	COG0708	Exodeoxyribonuclease III
A7A70_RS00155	COG2169	Transcriptional regulator
A7A70_RS00160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7A70_RS00165	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A7A70_RS00175	COG2364	Membrane
A7A70_RS00190	COG2267	carboxylic ester hydrolase activity
A7A70_RS00195	COG5001	Diguanylate cyclase
A7A70_RS00195	COG3300	MHYT domain
A7A70_RS00230	COG0384	phenazine biosynthesis protein PhzF
A7A70_RS00240	COG1346	cytolysis
A7A70_RS00245	COG1380	Effector of murein hydrolase LrgA
A7A70_RS00250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS00270	COG1404	Belongs to the peptidase S8 family
A7A70_RS00275	COG3773	Cell wall hydrolase
A7A70_RS00290	COG1368	sulfuric ester hydrolase activity
A7A70_RS00295	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7A70_RS00305	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
A7A70_RS00330	COG1131	(ABC) transporter
A7A70_RS00350	COG4550	Control of competence regulator ComK, YlbF/YmcA
A7A70_RS00360	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7A70_RS00365	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7A70_RS00365	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7A70_RS00375	COG2359	stage V sporulation protein S
A7A70_RS00380	COG1692	metallophosphoesterase
A7A70_RS00400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A7A70_RS00405	COG1426	Protein conserved in bacteria
A7A70_RS00420	COG0300	oxidoreductase activity
A7A70_RS00425	COG0612	Peptidase, M16
A7A70_RS00430	COG0612	Peptidase, M16
A7A70_RS00435	COG1079	Belongs to the binding-protein-dependent transport system permease family
A7A70_RS00440	COG4603	Belongs to the binding-protein-dependent transport system permease family
A7A70_RS00445	COG3845	ABC transporter
A7A70_RS00450	COG1744	ABC transporter substrate-binding protein PnrA-like
A7A70_RS00455	COG2188	Transcriptional regulator
A7A70_RS00465	COG1674	ftsk spoiiie
A7A70_RS00475	COG0740	serine-type endopeptidase activity
A7A70_RS00480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7A70_RS00495	COG0527	aspartate kinase activity
A7A70_RS00505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A7A70_RS00510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7A70_RS00515	COG1873	PFAM PRC-barrel domain
A7A70_RS00520	COG0612	Peptidase, M16
A7A70_RS00525	COG0726	polysaccharide deacetylase
A7A70_RS00540	COG0196	riboflavin kinase activity
A7A70_RS00555	COG1550	Protein conserved in bacteria
A7A70_RS00565	COG1358	cellular component organization or biogenesis
A7A70_RS00570	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A7A70_RS00575	COG0195	Participates in both transcription termination and antitermination
A7A70_RS00595	COG0750	zinc metalloprotease
A7A70_RS00605	COG4589	Belongs to the CDS family
A7A70_RS00620	COG0528	UMP kinase activity
A7A70_RS00660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7A70_RS00665	COG0758	DNA mediated transformation
A7A70_RS00670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A7A70_RS00710	COG1837	Belongs to the UPF0109 family
A7A70_RS00720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7A70_RS00730	COG0552	protein localization to endoplasmic reticulum
A7A70_RS00735	COG1196	nuclear chromosome segregation
A7A70_RS00745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A70_RS00750	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS00755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A7A70_RS00770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A7A70_RS00775	COG1461	Dihydroxyacetone kinase
A7A70_RS00780	COG1302	Protein conserved in bacteria
A7A70_RS00795	COG1564	THIamine pyrophosphokinase
A7A70_RS00800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A7A70_RS00810	COG2815	serine threonine protein kinase
A7A70_RS00810	COG0515	serine threonine protein kinase
A7A70_RS00815	COG0631	protein serine/threonine phosphatase activity
A7A70_RS00825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7A70_RS00825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7A70_RS00835	COG0242	peptide deformylase activity
A7A70_RS00840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A7A70_RS00865	COG1561	YicC-like family, N-terminal region
A7A70_RS00885	COG0006	proline dipeptidase activity
A7A70_RS00900	COG3069	C4-dicarboxylate transmembrane transporter activity
A7A70_RS00965	COG0564	pseudouridine synthase activity
A7A70_RS00985	COG3599	regulation of cell shape
A7A70_RS00990	COG2302	S4 RNA-binding domain
A7A70_RS00995	COG0762	integral membrane protein
A7A70_RS01005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A7A70_RS01015	COG1873	PFAM PRC-barrel domain
A7A70_RS01020	COG1191	sigma factor activity
A7A70_RS01025	COG1191	sigma factor activity
A7A70_RS01035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7A70_RS01040	COG0849	cell division
A7A70_RS01045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A7A70_RS01060	COG0772	Belongs to the SEDS family
A7A70_RS01075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A7A70_RS01080	COG0768	penicillin binding
A7A70_RS01085	COG0768	penicillin binding
A7A70_RS01090	COG4839	cell division protein FtsL
A7A70_RS01105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7A70_RS01120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A7A70_RS01125	COG1399	metal-binding, possibly nucleic acid-binding protein
A7A70_RS01135	COG3480	Lon protease (S16) C-terminal proteolytic domain
A7A70_RS01140	COG1752	Esterase of the alpha-beta hydrolase superfamily
A7A70_RS01145	COG3314	Sporulation integral membrane protein YlbJ
A7A70_RS01155	COG0742	ribosomal rna small subunit methyltransferase
A7A70_RS01170	COG3679	Belongs to the UPF0342 family
A7A70_RS01175	COG0406	alpha-ribazole phosphatase activity
A7A70_RS01190	COG2340	Cysteine-rich secretory protein family
A7A70_RS01200	COG3336	cytochrome c oxidase
A7A70_RS01235	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A7A70_RS01245	COG0772	Belongs to the SEDS family
A7A70_RS01255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A7A70_RS01260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
A7A70_RS01270	COG4896	Protein conserved in bacteria
A7A70_RS01285	COG1217	gtp-binding protein TYPA
A7A70_RS01295	COG0483	inositol monophosphate 1-phosphatase activity
A7A70_RS01315	COG1982	Orn Lys Arg decarboxylase major
A7A70_RS01365	COG0022	dehydrogenase e1 component
A7A70_RS01370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7A70_RS01380	COG0242	peptide deformylase activity
A7A70_RS01385	COG0561	phosphatase activity
A7A70_RS01400	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7A70_RS01405	COG0569	domain protein
A7A70_RS01425	COG0583	DNA-binding transcription factor activity
A7A70_RS01430	COG0517	IMP dehydrogenase activity
A7A70_RS01440	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
A7A70_RS01450	COG4703	Protein of unknown function (DUF1797)
A7A70_RS01465	COG2200	EAL domain
A7A70_RS01470	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS01475	COG1408	metallophosphoesterase
A7A70_RS01490	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A7A70_RS01530	COG2814	Major facilitator Superfamily
A7A70_RS01550	COG3209	COG3209 Rhs family protein
A7A70_RS01560	COG2205	protein histidine kinase activity
A7A70_RS01570	COG0436	Aminotransferase
A7A70_RS01575	COG1609	Transcriptional regulator
A7A70_RS01580	COG3833	ABC-type maltose transport systems, permease component
A7A70_RS01585	COG1175	transmembrane transport
A7A70_RS01590	COG2182	Extracellular solute-binding protein
A7A70_RS01600	COG0366	Alpha amylase catalytic
A7A70_RS01605	COG3842	ATPase activity
A7A70_RS01645	COG0183	Belongs to the thiolase family
A7A70_RS01680	COG1695	Transcriptional regulator
A7A70_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS01705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7A70_RS01710	COG0436	Aminotransferase
A7A70_RS01745	COG2084	Dehydrogenase
A7A70_RS01755	COG2199	diguanylate cyclase activity
A7A70_RS01760	COG0778	Nitroreductase
A7A70_RS01790	COG3711	transcriptional antiterminator
A7A70_RS01800	COG2188	Transcriptional regulator
A7A70_RS01810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A7A70_RS01840	COG1547	Domain of unknown function (DUF309)
A7A70_RS01845	COG0456	acetyltransferase
A7A70_RS01855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A7A70_RS01860	COG4086	secreted protein
A7A70_RS01865	COG0561	phosphatase activity
A7A70_RS01870	COG0697	spore germination
A7A70_RS01885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A70_RS01910	COG0733	neurotransmitter:sodium symporter activity
A7A70_RS01930	COG1686	Belongs to the peptidase S11 family
A7A70_RS01940	COG1725	Transcriptional regulator
A7A70_RS01945	COG1131	(ABC) transporter
A7A70_RS01970	COG1846	Transcriptional regulator
A7A70_RS01985	COG0598	Magnesium transport protein CorA
A7A70_RS02010	COG4974	Belongs to the 'phage' integrase family
A7A70_RS02020	COG0735	belongs to the Fur family
A7A70_RS02025	COG1300	Membrane
A7A70_RS02045	COG0667	Aldo Keto reductase
A7A70_RS02050	COG0656	L-ascorbic acid biosynthetic process
A7A70_RS02055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A7A70_RS02055	COG0456	acetyltransferase
A7A70_RS02065	COG4085	toxin activity
A7A70_RS02065	COG1525	nuclease
A7A70_RS02065	COG0737	Belongs to the 5'-nucleotidase family
A7A70_RS02075	COG0596	Alpha beta hydrolase
A7A70_RS02080	COG2056	Na+-H+ antiporter family
A7A70_RS02085	COG1609	Transcriptional regulator
A7A70_RS02090	COG0456	acetyltransferase
A7A70_RS02095	COG1073	alpha beta
A7A70_RS02110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7A70_RS02110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7A70_RS02115	COG0307	riboflavin synthase, alpha
A7A70_RS02140	COG4106	trans-aconitate 2-methyltransferase activity
A7A70_RS02145	COG1073	alpha beta
A7A70_RS02145	COG2226	methyltransferase
A7A70_RS02160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7A70_RS02170	COG1757	Na H antiporter
A7A70_RS02175	COG0737	Belongs to the 5'-nucleotidase family
A7A70_RS02185	COG1522	sequence-specific DNA binding
A7A70_RS02205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7A70_RS02230	COG0300	oxidoreductase activity
A7A70_RS02235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS02240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A70_RS02245	COG1760	l-serine dehydratase
A7A70_RS02250	COG1760	l-serine dehydratase
A7A70_RS02285	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7A70_RS02290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS02305	COG1376	ErfK ybiS ycfS ynhG family protein
A7A70_RS02310	COG4129	membrane
A7A70_RS02315	COG1126	abc transporter atp-binding protein
A7A70_RS02320	COG0765	amino acid transport
A7A70_RS02325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A70_RS02345	COG2323	membrane
A7A70_RS02350	COG0772	Belongs to the SEDS family
A7A70_RS02360	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A70_RS02365	COG0022	dehydrogenase e1 component
A7A70_RS02370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7A70_RS02375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7A70_RS02390	COG0280	phosphate acetyltransferase
A7A70_RS02400	COG3829	transcription factor binding
A7A70_RS02400	COG3290	protein histidine kinase activity
A7A70_RS02410	COG0584	glycerophosphoryl diester phosphodiesterase
A7A70_RS02415	COG3093	addiction module antidote protein HigA
A7A70_RS02425	COG0745	RESPONSE REGULATOR receiver
A7A70_RS02435	COG0750	zinc metalloprotease
A7A70_RS02440	COG0497	DNA recombination
A7A70_RS02450	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A7A70_RS02460	COG0142	geranyltranstransferase activity
A7A70_RS02485	COG1302	Protein conserved in bacteria
A7A70_RS02490	COG0439	Biotin carboxylase
A7A70_RS02495	COG0511	ligase activity, forming carbon-carbon bonds
A7A70_RS02540	COG3854	ATPases associated with a variety of cellular activities
A7A70_RS02565	COG0006	proline dipeptidase activity
A7A70_RS02580	COG3872	metal-dependent enzyme
A7A70_RS02590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A7A70_RS02625	COG0095	Lipoate-protein ligase
A7A70_RS02630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A70_RS02640	COG1609	Transcriptional regulator
A7A70_RS02650	COG2076	Multidrug Resistance protein
A7A70_RS02655	COG2076	Multidrug Resistance protein
A7A70_RS02700	COG1725	Transcriptional regulator
A7A70_RS02735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7A70_RS02800	COG4970	Tfp pilus assembly protein FimT
A7A70_RS02810	COG1459	type II secretion system
A7A70_RS02815	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A7A70_RS02865	COG1410	methionine synthase
A7A70_RS02865	COG0646	methionine synthase
A7A70_RS02870	COG0646	methionine synthase
A7A70_RS02870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A7A70_RS02875	COG0626	cystathionine gamma-synthase activity
A7A70_RS02880	COG0626	cystathionine gamma-synthase activity
A7A70_RS02900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS02910	COG1940	carbohydrate kinase activity
A7A70_RS02915	COG4483	Protein conserved in bacteria
A7A70_RS02920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A7A70_RS02925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A7A70_RS02930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7A70_RS02935	COG0704	Plays a role in the regulation of phosphate uptake
A7A70_RS02945	COG0581	inorganic phosphate transmembrane transporter activity
A7A70_RS02950	COG0573	inorganic phosphate transmembrane transporter activity
A7A70_RS02955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7A70_RS02960	COG0768	penicillin binding
A7A70_RS02965	COG0477	Major facilitator Superfamily
A7A70_RS02970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7A70_RS02995	COG0735	belongs to the Fur family
A7A70_RS03000	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A7A70_RS03005	COG1121	(ABC) transporter
A7A70_RS03010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS03040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7A70_RS03045	COG2384	SAM-dependent methyltransferase
A7A70_RS03050	COG2010	Cytochrome c
A7A70_RS03055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A7A70_RS03060	COG0358	DNA primase activity
A7A70_RS03080	COG0517	IMP dehydrogenase activity
A7A70_RS03095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A7A70_RS03100	COG0295	cytidine deaminase activity
A7A70_RS03105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A7A70_RS03115	COG1480	7TM receptor with intracellular HD hydrolase
A7A70_RS03120	COG1702	phosphate starvation-inducible protein PhoH
A7A70_RS03140	COG1610	YqeY-like protein
A7A70_RS03145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A7A70_RS03155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7A70_RS03160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A7A70_RS03190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7A70_RS03195	COG1733	regulation of RNA biosynthetic process
A7A70_RS03220	COG1466	dna polymerase III delta subunit
A7A70_RS03230	COG0658	competence protein
A7A70_RS03230	COG2333	competence protein COMEC
A7A70_RS03235	COG2131	deaminase
A7A70_RS03240	COG1596	polysaccharide export
A7A70_RS03240	COG1555	photosystem II stabilization
A7A70_RS03245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A70_RS03250	COG2226	methyltransferase
A7A70_RS03255	COG0799	negative regulation of ribosome biogenesis
A7A70_RS03260	COG1713	HD superfamily hydrolase involved in NAD metabolism
A7A70_RS03270	COG1534	Rna-binding protein
A7A70_RS03280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A7A70_RS03285	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A7A70_RS03310	COG1595	DNA-templated transcription, initiation
A7A70_RS03320	COG0778	Nitroreductase
A7A70_RS03325	COG2357	RelA SpoT domain protein
A7A70_RS03335	COG1785	Belongs to the alkaline phosphatase family
A7A70_RS03345	COG2267	carboxylic ester hydrolase activity
A7A70_RS03380	COG1404	Belongs to the peptidase S8 family
A7A70_RS03390	COG3186	Phenylalanine-4-hydroxylase
A7A70_RS03400	COG2514	catechol 2,3-dioxygenase activity
A7A70_RS03405	COG2259	Doxx family
A7A70_RS03445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS03460	COG1012	belongs to the aldehyde dehydrogenase family
A7A70_RS03460	COG1454	alcohol dehydrogenase
A7A70_RS03465	COG0626	cystathionine gamma-synthase activity
A7A70_RS03470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7A70_RS03495	COG0768	penicillin binding
A7A70_RS03510	COG0826	peptidase U32
A7A70_RS03515	COG0826	peptidase U32
A7A70_RS03520	COG4122	O-methyltransferase activity
A7A70_RS03525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A7A70_RS03555	COG0628	permease
A7A70_RS03575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A7A70_RS03590	COG1104	cysteine desulfurase activity
A7A70_RS03595	COG1959	2 iron, 2 sulfur cluster binding
A7A70_RS03600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7A70_RS03615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A7A70_RS03640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7A70_RS03650	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A7A70_RS03650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A7A70_RS03655	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7A70_RS03660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7A70_RS03660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7A70_RS03670	COG2244	polysaccharide biosynthetic process
A7A70_RS03675	COG2323	membrane
A7A70_RS03685	COG1862	Preprotein translocase
A7A70_RS03715	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A7A70_RS03725	COG0697	spore germination
A7A70_RS03730	COG0640	Transcriptional regulator
A7A70_RS03755	COG0157	Belongs to the NadC ModD family
A7A70_RS03760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7A70_RS03765	COG1104	cysteine desulfurase activity
A7A70_RS03770	COG1827	regulation of RNA biosynthetic process
A7A70_RS03775	COG2258	MOSC domain
A7A70_RS03780	COG0077	Prephenate dehydratase
A7A70_RS03785	COG0577	efflux transmembrane transporter activity
A7A70_RS03790	COG0577	efflux transmembrane transporter activity
A7A70_RS03795	COG1136	(ABC) transporter
A7A70_RS03800	COG5002	protein histidine kinase activity
A7A70_RS03805	COG0745	RESPONSE REGULATOR receiver
A7A70_RS03815	COG3290	protein histidine kinase activity
A7A70_RS03825	COG2868	ribosomal protein
A7A70_RS03835	COG1530	ribonuclease E activity
A7A70_RS03845	COG0739	heme binding
A7A70_RS03850	COG2894	cell division
A7A70_RS03870	COG1077	Cell shape determining protein MreB Mrl
A7A70_RS03895	COG0285	dihydrofolate synthase activity
A7A70_RS03910	COG1388	LysM domain
A7A70_RS03920	COG0113	porphobilinogen synthase activity
A7A70_RS03925	COG1587	Uroporphyrinogen-III synthase
A7A70_RS03935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7A70_RS03945	COG1846	Transcriptional regulator
A7A70_RS03950	COG1764	response to oxidative stress
A7A70_RS03965	COG0470	DNA polymerase III
A7A70_RS03965	COG1067	ATP-dependent peptidase activity
A7A70_RS04020	COG0622	Phosphoesterase
A7A70_RS04035	COG5401	PFAM Sporulation and spore germination
A7A70_RS04055	COG1309	transcriptional regulator
A7A70_RS04070	COG2197	response regulator
A7A70_RS04075	COG2233	PERMEase
A7A70_RS04085	COG0402	S-adenosylhomocysteine deaminase activity
A7A70_RS04090	COG0402	S-adenosylhomocysteine deaminase activity
A7A70_RS04100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A70_RS04110	COG0444	Belongs to the ABC transporter superfamily
A7A70_RS04115	COG4608	Belongs to the ABC transporter superfamily
A7A70_RS04120	COG3275	phosphorelay sensor kinase activity
A7A70_RS04140	COG1396	sequence-specific DNA binding
A7A70_RS04145	COG0697	spore germination
A7A70_RS04155	COG1959	2 iron, 2 sulfur cluster binding
A7A70_RS04160	COG1668	transmembrane transport
A7A70_RS04165	COG4152	abc transporter atp-binding protein
A7A70_RS04170	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A7A70_RS04180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A7A70_RS04185	COG1876	peptidase activity
A7A70_RS04190	COG0824	Thioesterase
A7A70_RS04195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A7A70_RS04200	COG1053	succinate dehydrogenase
A7A70_RS04205	COG2009	succinate dehydrogenase
A7A70_RS04210	COG1719	4-vinyl reductase, 4VR
A7A70_RS04220	COG3118	belongs to the thioredoxin family
A7A70_RS04225	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
A7A70_RS04230	COG2086	electron transfer activity
A7A70_RS04235	COG1024	Enoyl-CoA hydratase
A7A70_RS04240	COG1309	transcriptional regulator
A7A70_RS04245	COG0318	PFAM AMP-dependent synthetase and ligase
A7A70_RS04255	COG2318	DinB family
A7A70_RS04285	COG1131	(ABC) transporter
A7A70_RS04290	COG2205	protein histidine kinase activity
A7A70_RS04295	COG0745	RESPONSE REGULATOR receiver
A7A70_RS04305	COG4895	conserved protein (DUF2196)
A7A70_RS04310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A7A70_RS04320	COG4509	Sortase family
A7A70_RS04325	COG1120	ATPase activity
A7A70_RS04340	COG5386	Cell surface protein
A7A70_RS04350	COG5386	Cell surface protein
A7A70_RS04355	COG1114	Component of the transport system for branched-chain amino acids
A7A70_RS04360	COG1187	pseudouridine synthase activity
A7A70_RS04380	COG1286	toxin biosynthetic process
A7A70_RS04425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7A70_RS04435	COG1418	mRNA catabolic process
A7A70_RS04470	COG2814	Major facilitator Superfamily
A7A70_RS04475	COG1566	PFAM secretion protein HlyD family protein
A7A70_RS04480	COG1309	transcriptional regulator
A7A70_RS04485	COG1363	Peptidase, m42
A7A70_RS04510	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7A70_RS04520	COG1484	DNA-dependent DNA replication
A7A70_RS04525	COG3611	Membrane attachment protein
A7A70_RS04535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A7A70_RS04540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7A70_RS04545	COG0237	dephospho-CoA kinase activity
A7A70_RS04550	COG1971	Probably functions as a manganese efflux pump
A7A70_RS04560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7A70_RS04560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7A70_RS04565	COG5002	protein histidine kinase activity
A7A70_RS04570	COG0745	RESPONSE REGULATOR receiver
A7A70_RS04590	COG0538	isocitrate dehydrogenase activity
A7A70_RS04595	COG0372	Belongs to the citrate synthase family
A7A70_RS04610	COG0628	permease
A7A70_RS04615	COG3030	protein affecting phage T7 exclusion by the F plasmid
A7A70_RS04640	COG1725	Transcriptional regulator
A7A70_RS04645	COG0281	malic enzyme
A7A70_RS04650	COG0587	DNA-directed DNA polymerase activity
A7A70_RS04665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A7A70_RS04690	COG4109	DRTGG domain
A7A70_RS04705	COG0006	proline dipeptidase activity
A7A70_RS04745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS04750	COG0662	Cupin 2, conserved barrel domain protein
A7A70_RS04760	COG1476	TRANSCRIPTIONal
A7A70_RS04775	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS04780	COG0589	response to stress
A7A70_RS04815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS04845	COG0827	DNA restriction-modification system
A7A70_RS04850	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
A7A70_RS04855	COG3874	Sporulation protein YtfJ
A7A70_RS04870	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A7A70_RS04880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7A70_RS04895	COG1104	cysteine desulfurase activity
A7A70_RS04905	COG0583	DNA-binding transcription factor activity
A7A70_RS04910	COG0697	spore germination
A7A70_RS04915	COG1309	transcriptional regulator
A7A70_RS04920	COG1956	GAF domain-containing protein
A7A70_RS04925	COG0626	cystathionine gamma-synthase activity
A7A70_RS04955	COG1595	DNA-templated transcription, initiation
A7A70_RS04965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7A70_RS04970	COG0454	-acetyltransferase
A7A70_RS04975	COG0517	IMP dehydrogenase activity
A7A70_RS04980	COG0123	including yeast histone deacetylase and acetoin utilization protein
A7A70_RS04995	COG0745	RESPONSE REGULATOR receiver
A7A70_RS05000	COG5002	protein histidine kinase activity
A7A70_RS05005	COG0666	response to abiotic stimulus
A7A70_RS05040	COG1609	Transcriptional regulator
A7A70_RS05050	COG4851	CamS sex pheromone cAM373 precursor
A7A70_RS05055	COG3118	belongs to the thioredoxin family
A7A70_RS05065	COG2309	aminopeptidase activity
A7A70_RS05080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS05085	COG0697	spore germination
A7A70_RS05090	COG0789	Transcriptional regulator
A7A70_RS05095	COG1695	Transcriptional regulator
A7A70_RS05115	COG1674	ftsk spoiiie
A7A70_RS05130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A70_RS05140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A70_RS05145	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
A7A70_RS05150	COG1363	Peptidase, m42
A7A70_RS05160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS05175	COG0510	thiamine kinase activity
A7A70_RS05180	COG1523	belongs to the glycosyl hydrolase 13 family
A7A70_RS05195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A70_RS05200	COG1349	DNA-binding transcription factor activity
A7A70_RS05205	COG1187	pseudouridine synthase activity
A7A70_RS05210	COG2244	polysaccharide biosynthetic process
A7A70_RS05215	COG2081	HI0933 family
A7A70_RS05225	COG2814	Major facilitator Superfamily
A7A70_RS05235	COG3832	glyoxalase III activity
A7A70_RS05260	COG1329	Transcriptional regulator
A7A70_RS05285	COG0314	molybdopterin synthase activity
A7A70_RS05290	COG1763	Mo-molybdopterin cofactor biosynthetic process
A7A70_RS05295	COG0303	'Molybdopterin
A7A70_RS05305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7A70_RS05310	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7A70_RS05335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A70_RS05345	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A7A70_RS05395	COG2814	Major facilitator Superfamily
A7A70_RS05400	COG0475	glutathione-regulated potassium exporter activity
A7A70_RS05405	COG0490	domain, Protein
A7A70_RS05410	COG0582	viral genome integration into host DNA
A7A70_RS05420	COG1136	(ABC) transporter
A7A70_RS05440	COG1242	4 iron, 4 sulfur cluster binding
A7A70_RS05445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A7A70_RS05460	COG1794	racemase activity, acting on amino acids and derivatives
A7A70_RS05485	COG2267	carboxylic ester hydrolase activity
A7A70_RS05490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A7A70_RS05495	COG0671	phosphoesterase, PA-phosphatase related
A7A70_RS05500	COG0438	transferase activity, transferring glycosyl groups
A7A70_RS05510	COG0521	Mo-molybdopterin cofactor biosynthetic process
A7A70_RS05525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS05595	COG5002	protein histidine kinase activity
A7A70_RS05600	COG4191	Histidine kinase
A7A70_RS05605	COG2267	carboxylic ester hydrolase activity
A7A70_RS05610	COG1368	sulfuric ester hydrolase activity
A7A70_RS05625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7A70_RS05630	COG1116	anion transmembrane transporter activity
A7A70_RS05635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7A70_RS05660	COG0494	nUDIX hydrolase
A7A70_RS05695	COG0288	reversible hydration of carbon dioxide
A7A70_RS05700	COG1271	oxidase subunit
A7A70_RS05705	COG1294	oxidase, subunit
A7A70_RS05730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS05805	COG5002	protein histidine kinase activity
A7A70_RS05810	COG0745	RESPONSE REGULATOR receiver
A7A70_RS05835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A7A70_RS05840	COG1597	lipid kinase activity
A7A70_RS05855	COG0577	efflux transmembrane transporter activity
A7A70_RS05860	COG1136	(ABC) transporter
A7A70_RS05885	COG0586	Pfam SNARE associated Golgi protein
A7A70_RS05895	COG4977	sequence-specific DNA binding
A7A70_RS05905	COG0577	efflux transmembrane transporter activity
A7A70_RS05910	COG1136	(ABC) transporter
A7A70_RS05915	COG3708	Transcriptional regulator
A7A70_RS05915	COG2207	Transcriptional regulator
A7A70_RS05920	COG5658	integral membrane protein
A7A70_RS05925	COG0640	Transcriptional regulator
A7A70_RS05930	COG0745	RESPONSE REGULATOR receiver
A7A70_RS05935	COG2205	protein histidine kinase activity
A7A70_RS05940	COG0577	efflux transmembrane transporter activity
A7A70_RS05945	COG0577	efflux transmembrane transporter activity
A7A70_RS05950	COG1136	(ABC) transporter
A7A70_RS05955	COG0577	efflux transmembrane transporter activity
A7A70_RS05985	COG2188	Transcriptional regulator
A7A70_RS06040	COG1136	(ABC) transporter
A7A70_RS06045	COG0577	efflux transmembrane transporter activity
A7A70_RS06050	COG4948	Mandelate Racemase Muconate Lactonizing
A7A70_RS06060	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A7A70_RS06065	COG0596	Alpha beta hydrolase
A7A70_RS06075	COG1169	isochorismate synthase
A7A70_RS06080	COG1575	Belongs to the MenA family. Type 1 subfamily
A7A70_RS06085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A7A70_RS06115	COG0058	SHG alpha-glucan phosphorylase activity
A7A70_RS06125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7A70_RS06160	COG1595	DNA-templated transcription, initiation
A7A70_RS06255	COG0544	peptidyl-prolyl cis-trans isomerase activity
A7A70_RS06290	COG1285	pathogenesis
A7A70_RS06295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A7A70_RS06315	COG2155	Conserved Protein
A7A70_RS06320	COG1098	S1 RNA binding domain
A7A70_RS06325	COG0436	Aminotransferase
A7A70_RS06330	COG1522	sequence-specific DNA binding
A7A70_RS06335	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7A70_RS06340	COG2267	carboxylic ester hydrolase activity
A7A70_RS06350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
A7A70_RS06370	COG5018	Exonuclease
A7A70_RS06395	COG2050	protein possibly involved in aromatic compounds catabolism
A7A70_RS06405	COG1268	BioY protein
A7A70_RS06410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7A70_RS06415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7A70_RS06430	COG3584	3D domain protein
A7A70_RS06445	COG1252	NADH dehydrogenase
A7A70_RS06455	COG3708	Transcriptional regulator
A7A70_RS06470	COG1683	Conserved Protein
A7A70_RS06495	COG0316	Belongs to the HesB IscA family
A7A70_RS06510	COG1252	NADH dehydrogenase
A7A70_RS06525	COG0390	transport system, permease component
A7A70_RS06530	COG2824	Alkylphosphonate utilization operon protein PhnA
A7A70_RS06550	COG4837	Protein of unknown function (DUF1462)
A7A70_RS06555	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A7A70_RS06570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A70_RS06575	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A7A70_RS06585	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7A70_RS06590	COG0647	UMP catabolic process
A7A70_RS06600	COG2445	Protein of unknown function DUF86
A7A70_RS06605	COG1494	fructose-1,6-bisphosphatase
A7A70_RS06625	COG4470	Protein conserved in bacteria
A7A70_RS06640	COG4377	Putative membrane peptidase family (DUF2324)
A7A70_RS06665	COG0739	heme binding
A7A70_RS06675	COG3377	Domain of unknown function (DUF1805)
A7A70_RS06680	COG0737	Belongs to the 5'-nucleotidase family
A7A70_RS06685	COG1695	Transcriptional regulator
A7A70_RS06695	COG0719	Fe-S assembly protein
A7A70_RS06700	COG0822	iron-sulfur transferase activity
A7A70_RS06705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7A70_RS06710	COG0719	Fe-S assembly protein
A7A70_RS06715	COG0396	ATPase activity
A7A70_RS06720	COG1464	Belongs to the NlpA lipoprotein family
A7A70_RS06725	COG1464	Belongs to the NlpA lipoprotein family
A7A70_RS06730	COG2011	ABC-type metal ion transport system permease component
A7A70_RS06735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7A70_RS06745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A70_RS06750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7A70_RS06760	COG1393	Belongs to the ArsC family
A7A70_RS06845	COG1309	transcriptional regulator
A7A70_RS06850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS06855	COG1960	acyl-CoA dehydrogenase activity
A7A70_RS06865	COG0183	Belongs to the thiolase family
A7A70_RS06870	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7A70_RS06870	COG1024	Enoyl-CoA hydratase
A7A70_RS06880	COG1686	Belongs to the peptidase S11 family
A7A70_RS06895	COG0011	TIGRFAM Protein of
A7A70_RS06900	COG0840	transmembrane signaling receptor activity
A7A70_RS06920	COG2814	Major facilitator Superfamily
A7A70_RS06925	COG0531	amino acid
A7A70_RS06950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS06990	COG0586	Pfam SNARE associated Golgi protein
A7A70_RS07000	COG1376	ErfK ybiS ycfS ynhG family protein
A7A70_RS07005	COG0745	RESPONSE REGULATOR receiver
A7A70_RS07010	COG5002	protein histidine kinase activity
A7A70_RS07030	COG0840	transmembrane signaling receptor activity
A7A70_RS07035	COG0840	transmembrane signaling receptor activity
A7A70_RS07040	COG2151	metal-sulfur cluster biosynthetic enzyme
A7A70_RS07050	COG3227	Zinc metalloprotease (Elastase)
A7A70_RS07055	COG1741	Belongs to the pirin family
A7A70_RS07070	COG0586	Pfam SNARE associated Golgi protein
A7A70_RS07075	COG0475	glutathione-regulated potassium exporter activity
A7A70_RS07080	COG0490	domain, Protein
A7A70_RS07090	COG1115	amino acid carrier protein
A7A70_RS07095	COG0783	Belongs to the Dps family
A7A70_RS07115	COG1611	Belongs to the LOG family
A7A70_RS07135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS07140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS07145	COG1115	amino acid carrier protein
A7A70_RS07150	COG1115	amino acid carrier protein
A7A70_RS07155	COG2910	NAD(P)H-binding
A7A70_RS07170	COG0656	L-ascorbic acid biosynthetic process
A7A70_RS07175	COG2814	Major facilitator Superfamily
A7A70_RS07180	COG1733	regulation of RNA biosynthetic process
A7A70_RS07190	COG1252	NADH dehydrogenase
A7A70_RS07200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A7A70_RS07215	COG3290	protein histidine kinase activity
A7A70_RS07215	COG0840	transmembrane signaling receptor activity
A7A70_RS07225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7A70_RS07245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS07320	COG1309	transcriptional regulator
A7A70_RS07340	COG0557	exoribonuclease II activity
A7A70_RS07345	COG1647	Serine aminopeptidase, S33
A7A70_RS07350	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7A70_RS07355	COG1346	cytolysis
A7A70_RS07390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7A70_RS07405	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
A7A70_RS07430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A70_RS07445	COG2323	membrane
A7A70_RS07455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A70_RS07465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
A7A70_RS07475	COG1051	belongs to the nudix hydrolase family
A7A70_RS07485	COG0492	ferredoxin-NADP+ reductase activity
A7A70_RS07490	COG0457	Tetratricopeptide repeat
A7A70_RS07495	COG0110	maltose O-acetyltransferase activity
A7A70_RS07515	COG1950	PFAM Membrane protein of
A7A70_RS07525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7A70_RS07530	COG0556	nucleotide-excision repair
A7A70_RS07545	COG0789	Transcriptional regulator
A7A70_RS07565	COG0583	DNA-binding transcription factor activity
A7A70_RS07575	COG0655	NAD(P)H dehydrogenase (quinone) activity
A7A70_RS07580	COG0488	(ABC) transporter
A7A70_RS07595	COG1132	(ABC) transporter
A7A70_RS07605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A70_RS07610	COG3409	Peptidoglycan-binding domain 1 protein
A7A70_RS07610	COG0793	Belongs to the peptidase S41A family
A7A70_RS07615	COG2177	Part of the ABC transporter FtsEX involved in
A7A70_RS07620	COG2884	Cell division ATP-binding protein ftsE
A7A70_RS07630	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
A7A70_RS07640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A7A70_RS07645	COG1278	Cold shock
A7A70_RS07650	COG1040	competence protein
A7A70_RS07665	COG1733	regulation of RNA biosynthetic process
A7A70_RS07675	COG1307	EDD domain protein, DegV family
A7A70_RS07680	COG1739	Uncharacterized protein family UPF0029
A7A70_RS07685	COG1316	TRANSCRIPTIONal
A7A70_RS07690	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
A7A70_RS07695	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A7A70_RS07700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7A70_RS07710	COG3933	PFAM sigma-54 factor interaction domain-containing protein
A7A70_RS07710	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
A7A70_RS07730	COG1486	melibiose metabolic process
A7A70_RS07735	COG1447	Phosphotransferase system cellobiose-specific component IIA
A7A70_RS07740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A70_RS07760	COG1447	Phosphotransferase system cellobiose-specific component IIA
A7A70_RS07770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A70_RS07775	COG1301	dicarboxylic acid transport
A7A70_RS07785	COG0346	lactoylglutathione lyase activity
A7A70_RS07790	COG1511	domain protein
A7A70_RS07795	COG0583	DNA-binding transcription factor activity
A7A70_RS07800	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
A7A70_RS07810	COG1271	oxidase subunit
A7A70_RS07815	COG1294	oxidase, subunit
A7A70_RS07820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7A70_RS07830	COG1620	l-lactate permease
A7A70_RS07840	COG2389	metal-binding protein
A7A70_RS07850	COG1368	sulfuric ester hydrolase activity
A7A70_RS07860	COG1388	LysM domain
A7A70_RS07860	COG0791	NLP P60 protein
A7A70_RS07865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS07875	COG1215	transferase activity, transferring glycosyl groups
A7A70_RS07885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7A70_RS07895	COG3584	3D domain protein
A7A70_RS07895	COG1388	LysM domain
A7A70_RS07920	COG4715	Zinc finger, swim domain protein
A7A70_RS07925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7A70_RS07965	COG0577	efflux transmembrane transporter activity
A7A70_RS07970	COG1136	(ABC) transporter
A7A70_RS07995	COG5002	protein histidine kinase activity
A7A70_RS08000	COG0745	RESPONSE REGULATOR receiver
A7A70_RS08005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7A70_RS08025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A7A70_RS08030	COG1134	teichoic acid transport
A7A70_RS08035	COG1682	transport, permease protein
A7A70_RS08040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7A70_RS08055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
A7A70_RS08065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7A70_RS08075	COG1609	Transcriptional regulator
A7A70_RS08085	COG0739	heme binding
A7A70_RS08100	COG3279	Response regulator of the LytR AlgR family
A7A70_RS08105	COG2385	sporulation resulting in formation of a cellular spore
A7A70_RS08120	COG4836	Membrane
A7A70_RS08125	COG1007	ATP synthesis coupled electron transport
A7A70_RS08130	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7A70_RS08135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7A70_RS08145	COG0839	Belongs to the complex I subunit 6 family
A7A70_RS08165	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7A70_RS08180	COG3300	MHYT domain
A7A70_RS08180	COG5001	Diguanylate cyclase
A7A70_RS08230	COG0356	it plays a direct role in the translocation of protons across the membrane
A7A70_RS08265	COG0698	ribose 5-phosphate isomerase
A7A70_RS08275	COG2190	(PTS) system
A7A70_RS08280	COG2259	Doxx family
A7A70_RS08285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7A70_RS08300	COG0009	L-threonylcarbamoyladenylate synthase
A7A70_RS08315	COG2890	protein-(glutamine-N5) methyltransferase activity
A7A70_RS08335	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A7A70_RS08345	COG1494	fructose-1,6-bisphosphatase
A7A70_RS08365	COG4821	SIS domain
A7A70_RS08385	COG1960	acyl-CoA dehydrogenase activity
A7A70_RS08390	COG1960	acyl-CoA dehydrogenase activity
A7A70_RS08395	COG1250	3-hydroxyacyl-CoA dehydrogenase
A7A70_RS08400	COG0183	Belongs to the thiolase family
A7A70_RS08405	COG2181	nitrate reductase activity
A7A70_RS08405	COG0247	lactate metabolic process
A7A70_RS08420	COG5001	Diguanylate cyclase
A7A70_RS08420	COG3300	MHYT domain
A7A70_RS08445	COG2197	response regulator
A7A70_RS08450	COG4585	Histidine kinase
A7A70_RS08455	COG0842	Transport permease protein
A7A70_RS08460	COG1131	(ABC) transporter
A7A70_RS08465	COG0024	Methionine aminopeptidase
A7A70_RS08470	COG2234	aminopeptidase activity
A7A70_RS08515	COG1595	DNA-templated transcription, initiation
A7A70_RS08525	COG4506	Protein conserved in bacteria
A7A70_RS08530	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7A70_RS08555	COG2814	Major facilitator Superfamily
A7A70_RS08560	COG0789	Transcriptional regulator
A7A70_RS08565	COG0584	glycerophosphoryl diester phosphodiesterase
A7A70_RS08570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A70_RS08580	COG1994	Peptidase M50
A7A70_RS08590	COG1078	dGTPase activity
A7A70_RS08595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS08600	COG1120	ATPase activity
A7A70_RS08605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS08610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS08635	COG0280	phosphate acetyltransferase
A7A70_RS08650	COG3773	Cell wall hydrolase
A7A70_RS08660	COG2363	Small membrane protein
A7A70_RS08670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A7A70_RS08675	COG2233	PERMEase
A7A70_RS08680	COG0561	phosphatase activity
A7A70_RS08685	COG2814	Major facilitator Superfamily
A7A70_RS08695	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A7A70_RS08700	COG1131	(ABC) transporter
A7A70_RS08705	COG2755	lipolytic protein G-D-S-L family
A7A70_RS08710	COG1609	Transcriptional regulator
A7A70_RS08720	COG0460	homoserine dehydrogenase
A7A70_RS08730	COG2873	o-acetylhomoserine
A7A70_RS08740	COG1011	Hydrolase
A7A70_RS08745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7A70_RS08755	COG2197	response regulator
A7A70_RS08760	COG2203	Gaf domain
A7A70_RS08760	COG4585	Histidine kinase
A7A70_RS08765	COG0351	phosphomethylpyrimidine kinase
A7A70_RS08770	COG3706	GGDEF domain
A7A70_RS08775	COG2879	small protein
A7A70_RS08780	COG1966	Carbon starvation protein
A7A70_RS08785	COG3279	Response regulator of the LytR AlgR family
A7A70_RS08790	COG0477	Major facilitator Superfamily
A7A70_RS08830	COG1607	acyl-coa hydrolase
A7A70_RS08845	COG0488	(ABC) transporter
A7A70_RS08865	COG0463	Glycosyl transferase, family 2
A7A70_RS08870	COG1309	transcriptional regulator
A7A70_RS08875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A7A70_RS08880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7A70_RS08880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A7A70_RS08885	COG0628	permease
A7A70_RS08900	COG3279	Response regulator of the LytR AlgR family
A7A70_RS08905	COG3275	phosphorelay sensor kinase activity
A7A70_RS08910	COG2814	Major facilitator Superfamily
A7A70_RS08915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7A70_RS08920	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
A7A70_RS08930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7A70_RS08950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7A70_RS08955	COG1272	protein, Hemolysin III
A7A70_RS09000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A70_RS09005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A7A70_RS09010	COG4853	Protein conserved in bacteria
A7A70_RS09015	COG4863	YycH protein
A7A70_RS09020	COG5002	protein histidine kinase activity
A7A70_RS09025	COG0745	RESPONSE REGULATOR receiver
A7A70_RS09055	COG0305	Participates in initiation and elongation during chromosome replication
A7A70_RS09065	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7A70_RS09070	COG4241	membrane
A7A70_RS09080	COG0629	single-stranded DNA binding
A7A70_RS09090	COG0012	GTP binding
A7A70_RS09095	COG4481	Protein conserved in bacteria
A7A70_RS09100	COG0668	transmembrane transport
A7A70_RS09110	COG1475	DNA binding
A7A70_RS09115	COG1192	Involved in chromosome partitioning
A7A70_RS09140	COG1847	R3H domain protein
A7A70_RS09145	COG0706	membrane insertase activity
A7A70_RS09155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A7A70_RS09165	COG0592	DNA-directed DNA polymerase activity
A7A70_RS09170	COG2501	S4 domain
A7A70_RS09180	COG0187	DNA topoisomerase II activity
A7A70_RS09185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7A70_RS09220	COG0517	IMP dehydrogenase activity
A7A70_RS09220	COG0516	GMP reductase activity
A7A70_RS09225	COG1686	Belongs to the peptidase S11 family
A7A70_RS09255	COG1428	Deoxynucleoside kinase
A7A70_RS09260	COG1428	Deoxynucleoside kinase
A7A70_RS09265	COG1335	isochorismatase
A7A70_RS09275	COG0590	tRNA wobble adenosine to inosine editing
A7A70_RS09285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A7A70_RS09330	COG1982	Orn Lys Arg decarboxylase major
A7A70_RS09340	COG0470	DNA polymerase III
A7A70_RS09345	COG1774	PSP1 C-terminal conserved region
A7A70_RS09355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A7A70_RS09365	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A7A70_RS09370	COG2002	toxin-antitoxin pair type II binding
A7A70_RS09380	COG0084	hydrolase, TatD family'
A7A70_RS09385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
A7A70_RS09400	COG4466	Protein conserved in bacteria
A7A70_RS09415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7A70_RS09420	COG0251	oxidation-reduction process
A7A70_RS09455	COG2002	toxin-antitoxin pair type II binding
A7A70_RS09460	COG2244	polysaccharide biosynthetic process
A7A70_RS09465	COG3956	TIGRFAM MazG family protein
A7A70_RS09470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A7A70_RS09490	COG1098	S1 RNA binding domain
A7A70_RS09505	COG2208	phosphoserine phosphatase activity
A7A70_RS09515	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
A7A70_RS09520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7A70_RS09535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7A70_RS09540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A7A70_RS09545	COG0512	Glutamine amidotransferase of anthranilate synthase
A7A70_RS09550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A70_RS09555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7A70_RS09560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A7A70_RS09565	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A7A70_RS09570	COG1396	sequence-specific DNA binding
A7A70_RS09575	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7A70_RS09605	COG3880	PFAM UvrB UvrC protein
A7A70_RS09615	COG0542	response to heat
A7A70_RS09620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
A7A70_RS09630	COG4956	integral membrane protein (PIN domain superfamily)
A7A70_RS09640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A7A70_RS09650	COG1045	serine acetyltransferase
A7A70_RS09665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A7A70_RS09670	COG3688	RNA-binding protein containing a PIN domain
A7A70_RS09685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A7A70_RS09690	COG0250	Participates in transcription elongation, termination and antitermination
A7A70_RS09695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A7A70_RS09715	COG2813	Specifically methylates the guanine in position
A7A70_RS09730	COG1358	cellular component organization or biogenesis
A7A70_RS09805	COG0255	Belongs to the universal ribosomal protein uL29 family
A7A70_RS09865	COG0201	protein transport
A7A70_RS09875	COG0024	Methionine aminopeptidase
A7A70_RS09885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A7A70_RS09920	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7A70_RS09945	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS09950	COG0489	protein tyrosine kinase activity
A7A70_RS09960	COG2194	sulfuric ester hydrolase activity
A7A70_RS09965	COG0726	polysaccharide deacetylase
A7A70_RS10040	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A7A70_RS10045	COG4856	YbbR-like protein
A7A70_RS10060	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7A70_RS10065	COG0596	Alpha beta hydrolase
A7A70_RS10085	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A7A70_RS10110	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS10115	COG2011	ABC-type metal ion transport system permease component
A7A70_RS10120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A7A70_RS10125	COG1464	Belongs to the NlpA lipoprotein family
A7A70_RS10130	COG0604	alcohol dehydrogenase
A7A70_RS10140	COG0277	FAD linked oxidase domain protein
A7A70_RS10145	COG2271	Major facilitator Superfamily
A7A70_RS10155	COG2814	Major facilitator Superfamily
A7A70_RS10175	COG0601	transmembrane transport
A7A70_RS10180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A70_RS10185	COG0444	Belongs to the ABC transporter superfamily
A7A70_RS10190	COG4608	Belongs to the ABC transporter superfamily
A7A70_RS10195	COG4166	transmembrane transport
A7A70_RS10210	COG4166	transmembrane transport
A7A70_RS10215	COG4166	transmembrane transport
A7A70_RS10220	COG0656	L-ascorbic acid biosynthetic process
A7A70_RS10235	COG4149	molybdate abc transporter
A7A70_RS10240	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7A70_RS10245	COG1910	domain protein
A7A70_RS10265	COG0697	spore germination
A7A70_RS10285	COG0204	Acyl-transferase
A7A70_RS10305	COG1609	Transcriptional regulator
A7A70_RS10315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS10330	COG0084	hydrolase, TatD family'
A7A70_RS10340	COG5298	Protein conserved in bacteria
A7A70_RS10365	COG0488	(ABC) transporter
A7A70_RS10370	COG4585	Histidine kinase
A7A70_RS10375	COG2197	response regulator
A7A70_RS10380	COG1131	(ABC) transporter
A7A70_RS10385	COG1511	domain protein
A7A70_RS10385	COG0842	Transport permease protein
A7A70_RS10390	COG0842	Transport permease protein
A7A70_RS10400	COG0747	negative chemotaxis
A7A70_RS10405	COG0747	negative chemotaxis
A7A70_RS10410	COG0601	transmembrane transport
A7A70_RS10415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A70_RS10420	COG0444	Belongs to the ABC transporter superfamily
A7A70_RS10425	COG4608	Belongs to the ABC transporter superfamily
A7A70_RS10430	COG0561	phosphatase activity
A7A70_RS10465	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A7A70_RS10470	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7A70_RS10480	COG0531	amino acid
A7A70_RS10485	COG2814	Major facilitator Superfamily
A7A70_RS10495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7A70_RS10505	COG4294	response to UV
A7A70_RS10510	COG0705	Rhomboid family
A7A70_RS10520	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A7A70_RS10525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7A70_RS10530	COG0864	Transcriptional regulator
A7A70_RS10535	COG2337	Toxic component of a toxin-antitoxin (TA) module
A7A70_RS10540	COG2183	response to ionizing radiation
A7A70_RS10645	COG0802	atpase or kinase
A7A70_RS10650	COG1214	PFAM Peptidase M22, glycoprotease
A7A70_RS10655	COG0456	acetyltransferase
A7A70_RS10665	COG0488	(ABC) transporter
A7A70_RS10680	COG1266	CAAX protease self-immunity
A7A70_RS10690	COG0459	protein refolding
A7A70_RS10700	COG2252	PERMEase
A7A70_RS10735	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A7A70_RS10765	COG2226	methyltransferase
A7A70_RS10785	COG1215	transferase activity, transferring glycosyl groups
A7A70_RS10805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS10810	COG0506	proline dehydrogenase activity
A7A70_RS10830	COG0697	spore germination
A7A70_RS10860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7A70_RS10865	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A7A70_RS10870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7A70_RS10880	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7A70_RS10895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7A70_RS10905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A7A70_RS10915	COG0151	Belongs to the GarS family
A7A70_RS10945	COG0210	DNA helicase
A7A70_RS10975	COG1335	isochorismatase
A7A70_RS10990	COG2011	ABC-type metal ion transport system permease component
A7A70_RS10995	COG1464	Belongs to the NlpA lipoprotein family
A7A70_RS11010	COG0003	Pfam Anion-transporting ATPase
A7A70_RS11015	COG1846	Transcriptional regulator
A7A70_RS11020	COG4682	membrane
A7A70_RS11040	COG1597	lipid kinase activity
A7A70_RS11045	COG0546	phosphoglycolate phosphatase activity
A7A70_RS11050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7A70_RS11060	COG1012	belongs to the aldehyde dehydrogenase family
A7A70_RS11065	COG2076	Multidrug Resistance protein
A7A70_RS11070	COG2309	aminopeptidase activity
A7A70_RS11085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS11090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7A70_RS11095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A7A70_RS11100	COG5002	protein histidine kinase activity
A7A70_RS11105	COG4807	Protein conserved in bacteria
A7A70_RS11130	COG1757	Na H antiporter
A7A70_RS11135	COG1473	amidohydrolase
A7A70_RS11150	COG0450	alkyl hydroperoxide reductase
A7A70_RS11160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7A70_RS11170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS11175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS11180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS11205	COG0166	Belongs to the GPI family
A7A70_RS11240	COG4191	Histidine kinase
A7A70_RS11260	COG3541	Predicted nucleotidyltransferase
A7A70_RS11265	COG2814	Major facilitator Superfamily
A7A70_RS11270	COG0723	plastoquinol--plastocyanin reductase activity
A7A70_RS11270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A70_RS11280	COG0765	amino acid transport
A7A70_RS11285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A70_RS11295	COG0840	transmembrane signaling receptor activity
A7A70_RS11320	COG0549	Belongs to the carbamate kinase family
A7A70_RS11325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7A70_RS11335	COG0277	FAD linked oxidase domain protein
A7A70_RS11340	COG0366	Alpha amylase catalytic
A7A70_RS11345	COG2190	(PTS) system
A7A70_RS11345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A70_RS11345	COG1263	PTS System
A7A70_RS11380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
A7A70_RS11395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7A70_RS11405	COG1116	anion transmembrane transporter activity
A7A70_RS11415	COG0488	(ABC) transporter
A7A70_RS11460	COG2270	Major facilitator Superfamily
A7A70_RS11490	COG2310	stress, protein
A7A70_RS11495	COG2310	stress, protein
A7A70_RS11500	COG2310	stress, protein
A7A70_RS11505	COG0861	Integral membrane protein TerC family
A7A70_RS11515	COG3853	Toxic anion resistance protein (TelA)
A7A70_RS11530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A7A70_RS11540	COG1295	ribonuclease BN
A7A70_RS11545	COG2217	Heavy metal translocating P-type atpase
A7A70_RS11560	COG0681	Belongs to the peptidase S26 family
A7A70_RS11570	COG0586	Pfam SNARE associated Golgi protein
A7A70_RS11585	COG3871	stress protein (general stress protein 26)
A7A70_RS11590	COG0387	Pfam Sodium calcium exchanger
A7A70_RS11600	COG0535	radical SAM domain protein
A7A70_RS11620	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
A7A70_RS11650	COG0833	amino acid
A7A70_RS11655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A70_RS11695	COG1263	PTS System
A7A70_RS11695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A70_RS11700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A70_RS11735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A70_RS11735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A7A70_RS11755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A7A70_RS11780	COG1090	epimerase
A7A70_RS11810	COG1988	membrane-bound metal-dependent
A7A70_RS11815	COG1194	a g-specific adenine glycosylase
A7A70_RS11840	COG1132	(ABC) transporter
A7A70_RS11845	COG4129	membrane
A7A70_RS11850	COG0067	glutamate synthase
A7A70_RS11850	COG0070	glutamate synthase
A7A70_RS11850	COG0069	glutamate synthase activity
A7A70_RS11860	COG4555	ABC transporter
A7A70_RS11880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7A70_RS11885	COG0735	belongs to the Fur family
A7A70_RS12000	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A7A70_RS12005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A7A70_RS12020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A7A70_RS12030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A7A70_RS12045	COG2766	serine protein kinase
A7A70_RS12070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A7A70_RS12080	COG1585	Membrane protein implicated in regulation of membrane protease activity
A7A70_RS12085	COG2268	Band 7 protein
A7A70_RS12095	COG3290	protein histidine kinase activity
A7A70_RS12100	COG4565	transcriptional regulatory protein
A7A70_RS12105	COG2851	Citrate transporter
A7A70_RS12130	COG0745	RESPONSE REGULATOR receiver
A7A70_RS12135	COG5002	protein histidine kinase activity
A7A70_RS12145	COG4990	cell redox homeostasis
A7A70_RS12160	COG4565	transcriptional regulatory protein
A7A70_RS12165	COG3493	citrate carrier protein
A7A70_RS12170	COG0281	malic enzyme
A7A70_RS12180	COG0697	spore germination
A7A70_RS12185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS12195	COG5002	protein histidine kinase activity
A7A70_RS12200	COG0745	RESPONSE REGULATOR receiver
A7A70_RS12215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7A70_RS12220	COG3383	formate dehydrogenase (NAD+) activity
A7A70_RS12225	COG2427	Protein of unknown function (DUF1641)
A7A70_RS12240	COG0531	amino acid
A7A70_RS12245	COG0640	Transcriptional regulator
A7A70_RS12250	COG2217	Heavy metal translocating P-type atpase
A7A70_RS12255	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A7A70_RS12265	COG3227	Zinc metalloprotease (Elastase)
A7A70_RS12290	COG1316	TRANSCRIPTIONal
A7A70_RS12295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS12300	COG0346	lactoylglutathione lyase activity
A7A70_RS12305	COG1253	flavin adenine dinucleotide binding
A7A70_RS12310	COG1027	Aspartate ammonia-lyase
A7A70_RS12315	COG1620	l-lactate permease
A7A70_RS12330	COG3104	oligopeptide transport
A7A70_RS12335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS12340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS12345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS12355	COG2226	methyltransferase
A7A70_RS12360	COG0156	8-amino-7-oxononanoate synthase activity
A7A70_RS12365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7A70_RS12370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A7A70_RS12385	COG0714	Associated with various cellular activities
A7A70_RS12390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A70_RS12415	COG0531	amino acid
A7A70_RS12420	COG2188	Transcriptional regulator
A7A70_RS12425	COG1263	PTS System
A7A70_RS12425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A70_RS12430	COG0366	Alpha amylase catalytic
A7A70_RS12450	COG0697	spore germination
A7A70_RS12455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A70_RS12460	COG1115	amino acid carrier protein
A7A70_RS12465	COG1126	abc transporter atp-binding protein
A7A70_RS12470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A70_RS12475	COG0765	amino acid transport
A7A70_RS12480	COG0765	amino acid transport
A7A70_RS12485	COG0833	amino acid
A7A70_RS12500	COG1595	DNA-templated transcription, initiation
A7A70_RS12510	COG2378	regulation of single-species biofilm formation
A7A70_RS12515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7A70_RS12520	COG5002	protein histidine kinase activity
A7A70_RS12535	COG0659	secondary active sulfate transmembrane transporter activity
A7A70_RS12560	COG0601	transmembrane transport
A7A70_RS12565	COG4608	Belongs to the ABC transporter superfamily
A7A70_RS12575	COG2271	Major facilitator Superfamily
A7A70_RS12580	COG1846	Transcriptional regulator
A7A70_RS12585	COG0477	Major facilitator Superfamily
A7A70_RS12590	COG1609	Transcriptional regulator
A7A70_RS12595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A70_RS12610	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7A70_RS12615	COG1879	ABC-type sugar transport system periplasmic component
A7A70_RS12635	COG1063	alcohol dehydrogenase
A7A70_RS12650	COG3568	Endonuclease Exonuclease Phosphatase
A7A70_RS12680	COG0840	transmembrane signaling receptor activity
A7A70_RS12685	COG3584	3D domain protein
A7A70_RS12685	COG3583	domain protein
A7A70_RS12690	COG1476	TRANSCRIPTIONal
A7A70_RS12710	COG1114	Component of the transport system for branched-chain amino acids
A7A70_RS12725	COG1113	amino acid transport
A7A70_RS12730	COG2252	PERMEase
A7A70_RS12745	COG2153	protein acetylation
A7A70_RS12755	COG0569	domain protein
A7A70_RS12755	COG0475	glutathione-regulated potassium exporter activity
A7A70_RS12770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A7A70_RS12775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A7A70_RS12780	COG0833	amino acid
A7A70_RS12785	COG4990	cell redox homeostasis
A7A70_RS12800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A70_RS12805	COG0697	spore germination
A7A70_RS12810	COG0531	amino acid
A7A70_RS12825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7A70_RS12830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7A70_RS12835	COG1918	ferrous iron import across plasma membrane
A7A70_RS12835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
A7A70_RS12840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A7A70_RS12845	COG0573	inorganic phosphate transmembrane transporter activity
A7A70_RS12850	COG0581	inorganic phosphate transmembrane transporter activity
A7A70_RS12980	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
A7A70_RS13005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A7A70_RS13010	COG1116	anion transmembrane transporter activity
A7A70_RS13015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7A70_RS13020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7A70_RS13025	COG0352	thiamine-phosphate diphosphorylase activity
A7A70_RS13030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A70_RS13035	COG2104	thiamine diphosphate biosynthetic process
A7A70_RS13045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7A70_RS13050	COG0351	phosphomethylpyrimidine kinase
A7A70_RS13090	COG2205	protein histidine kinase activity
A7A70_RS13100	COG1846	Transcriptional regulator
A7A70_RS13115	COG2252	PERMEase
A7A70_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS13135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7A70_RS13140	COG1621	beta-fructofuranosidase activity
A7A70_RS13145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A70_RS13145	COG1263	PTS System
A7A70_RS13150	COG1609	Transcriptional regulator
A7A70_RS13160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A70_RS13200	COG0778	Nitroreductase
A7A70_RS13205	COG2719	SpoVR family
A7A70_RS13210	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7A70_RS13215	COG1937	Protein conserved in bacteria
A7A70_RS13220	COG0425	Belongs to the sulfur carrier protein TusA family
A7A70_RS13220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A70_RS13225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A70_RS13225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS13230	COG0425	Belongs to the sulfur carrier protein TusA family
A7A70_RS13235	COG0425	Belongs to the sulfur carrier protein TusA family
A7A70_RS13245	COG0425	Belongs to the sulfur carrier protein TusA family
A7A70_RS13245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7A70_RS13255	COG2210	Belongs to the sulfur carrier protein TusA family
A7A70_RS13260	COG0730	response to heat
A7A70_RS13275	COG0604	alcohol dehydrogenase
A7A70_RS13280	COG1283	sodium-dependent phosphate transmembrane transporter activity
A7A70_RS13285	COG2814	Major facilitator Superfamily
A7A70_RS13295	COG3711	transcriptional antiterminator
A7A70_RS13295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A70_RS13300	COG1447	Phosphotransferase system cellobiose-specific component IIA
A7A70_RS13305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A7A70_RS13330	COG3584	3D domain protein
A7A70_RS13330	COG1388	LysM domain
A7A70_RS13335	COG0577	efflux transmembrane transporter activity
A7A70_RS13340	COG1136	(ABC) transporter
A7A70_RS13345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A7A70_RS13350	COG5522	Integral membrane protein (intg_mem_TP0381)
A7A70_RS13365	COG1114	Component of the transport system for branched-chain amino acids
A7A70_RS13405	COG0586	Pfam SNARE associated Golgi protein
A7A70_RS13440	COG0531	amino acid
A7A70_RS13445	COG0475	glutathione-regulated potassium exporter activity
A7A70_RS13455	COG1737	Transcriptional regulator
A7A70_RS13465	COG1263	PTS System
A7A70_RS13465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A70_RS13475	COG2259	Doxx family
A7A70_RS13495	COG1522	sequence-specific DNA binding
A7A70_RS13505	COG0300	oxidoreductase activity
A7A70_RS13520	COG2076	Multidrug Resistance protein
A7A70_RS13525	COG1309	transcriptional regulator
A7A70_RS13530	COG2814	Major facilitator Superfamily
A7A70_RS13535	COG1733	regulation of RNA biosynthetic process
A7A70_RS13545	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7A70_RS13550	COG0747	negative chemotaxis
A7A70_RS13555	COG2211	Major facilitator Superfamily
A7A70_RS13565	COG0693	protein deglycase activity
A7A70_RS13570	COG0753	catalase activity
A7A70_RS13580	COG0531	amino acid
A7A70_RS13585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A7A70_RS13595	COG1012	belongs to the aldehyde dehydrogenase family
A7A70_RS13615	COG1132	(ABC) transporter
A7A70_RS13620	COG1132	(ABC) transporter
A7A70_RS13630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A70_RS13635	COG0765	amino acid transport
A7A70_RS13640	COG1126	abc transporter atp-binding protein
A7A70_RS13655	COG0189	ligase activity
A7A70_RS13685	COG0028	Belongs to the TPP enzyme family
A7A70_RS13690	COG3527	Alpha-acetolactate decarboxylase
A7A70_RS13705	COG0561	phosphatase activity
A7A70_RS13715	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS13715	COG3409	Peptidoglycan-binding domain 1 protein
A7A70_RS13720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A7A70_RS13740	COG0659	secondary active sulfate transmembrane transporter activity
A7A70_RS13755	COG0653	protein targeting
A7A70_RS13760	COG2244	polysaccharide biosynthetic process
A7A70_RS13775	COG4196	transglutaminase domain protein
A7A70_RS13795	COG1024	Enoyl-CoA hydratase
A7A70_RS13815	COG1363	Peptidase, m42
A7A70_RS13870	COG0305	Participates in initiation and elongation during chromosome replication
A7A70_RS13920	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS13940	COG1396	sequence-specific DNA binding
A7A70_RS13945	COG3409	Peptidoglycan-binding domain 1 protein
A7A70_RS13960	COG0477	Major facilitator Superfamily
A7A70_RS13965	COG3290	protein histidine kinase activity
A7A70_RS13970	COG4565	transcriptional regulatory protein
A7A70_RS13975	COG3181	Tripartite tricarboxylate transporter family receptor
A7A70_RS14010	COG4978	Transcriptional regulator
A7A70_RS14010	COG0789	Transcriptional regulator
A7A70_RS14025	COG0305	Participates in initiation and elongation during chromosome replication
A7A70_RS14065	COG0477	Major facilitator Superfamily
A7A70_RS14140	COG3711	transcriptional antiterminator
A7A70_RS14145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A7A70_RS14145	COG2190	(PTS) system
A7A70_RS14145	COG1263	PTS System
A7A70_RS14150	COG2723	6-phospho-beta-galactosidase activity
A7A70_RS14160	COG1183	phosphatidylcholine synthase activity
A7A70_RS14180	COG2376	Dihydroxyacetone kinase
A7A70_RS14190	COG2376	Dihydroxyacetone kinase
A7A70_RS14220	COG3437	response regulator, receiver
A7A70_RS14220	COG2770	Histidine kinase
A7A70_RS14285	COG1136	(ABC) transporter
A7A70_RS14290	COG0577	efflux transmembrane transporter activity
A7A70_RS14295	COG0596	Alpha beta hydrolase
A7A70_RS14315	COG3237	CsbD-like
A7A70_RS14340	COG1191	sigma factor activity
A7A70_RS14350	COG2208	phosphoserine phosphatase activity
A7A70_RS14355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A7A70_RS14360	COG2205	protein histidine kinase activity
A7A70_RS14360	COG2198	Histidine kinase
A7A70_RS14360	COG0784	Response regulator, receiver
A7A70_RS14420	COG0420	3'-5' exonuclease activity
A7A70_RS14425	COG4717	serine-type aminopeptidase activity
A7A70_RS14435	COG1309	transcriptional regulator
A7A70_RS14440	COG2814	Major facilitator Superfamily
A7A70_RS14445	COG0346	lactoylglutathione lyase activity
A7A70_RS14450	COG0346	lactoylglutathione lyase activity
A7A70_RS14455	COG0457	Tetratricopeptide repeat
A7A70_RS14460	COG2267	carboxylic ester hydrolase activity
A7A70_RS14480	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
A7A70_RS14485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A7A70_RS14495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A7A70_RS14520	COG0772	Belongs to the SEDS family
A7A70_RS14540	COG0477	Major facilitator Superfamily
A7A70_RS14550	COG3973	AAA domain
A7A70_RS14555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7A70_RS14575	COG4980	gas vesicle protein
A7A70_RS14580	COG0537	adenosine 5'-monophosphoramidase activity
A7A70_RS14585	COG1131	(ABC) transporter
A7A70_RS14590	COG4473	ABC transporter
A7A70_RS14605	COG1309	transcriptional regulator
A7A70_RS14615	COG3402	PFAM membrane-flanked domain
A7A70_RS14660	COG1131	(ABC) transporter
A7A70_RS14665	COG1725	Transcriptional regulator
A7A70_RS14705	COG3428	Bacterial PH domain
A7A70_RS14715	COG2329	Antibiotic biosynthesis monooxygenase
A7A70_RS14720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A70_RS14735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7A70_RS14760	COG1309	transcriptional regulator
A7A70_RS14790	COG2378	regulation of single-species biofilm formation
A7A70_RS14795	COG1609	Transcriptional regulator
A7A70_RS14805	COG1234	tRNA 3'-trailer cleavage
A7A70_RS14810	COG0095	Lipoate-protein ligase
A7A70_RS14820	COG0318	PFAM AMP-dependent synthetase and ligase
A7A70_RS14845	COG1073	alpha beta
A7A70_RS14850	COG1408	metallophosphoesterase
A7A70_RS14855	COG1078	dGTPase activity
A7A70_RS14865	COG0477	Major facilitator Superfamily
A7A70_RS14875	COG1595	DNA-templated transcription, initiation
A7A70_RS14880	COG2207	Transcriptional regulator
A7A70_RS14880	COG3708	Transcriptional regulator
A7A70_RS14895	COG2205	protein histidine kinase activity
A7A70_RS14900	COG0745	RESPONSE REGULATOR receiver
A7A70_RS14925	COG0501	Belongs to the peptidase M48B family
A7A70_RS14930	COG0840	transmembrane signaling receptor activity
A7A70_RS14935	COG0697	spore germination
A7A70_RS14955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A7A70_RS14960	COG2224	Isocitrate lyase
A7A70_RS14985	COG4903	ComK protein
A7A70_RS14995	COG0398	Pfam SNARE associated Golgi protein
A7A70_RS15080	COG0367	asparagine synthase
A7A70_RS15095	COG0004	ammonium transporteR
A7A70_RS15130	COG2996	Protein conserved in bacteria
A7A70_RS15135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7A70_RS15145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS15160	COG0561	phosphatase activity
A7A70_RS15190	COG2267	carboxylic ester hydrolase activity
A7A70_RS15205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A70_RS15210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A7A70_RS15215	COG5504	Zn-dependent protease
A7A70_RS15225	COG0180	Tryptophanyl-tRNA synthetase
A7A70_RS15240	COG4166	transmembrane transport
A7A70_RS15245	COG0601	transmembrane transport
A7A70_RS15250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7A70_RS15255	COG0444	Belongs to the ABC transporter superfamily
A7A70_RS15260	COG4608	Belongs to the ABC transporter superfamily
A7A70_RS15265	COG0534	Mate efflux family protein
A7A70_RS15270	COG4166	transmembrane transport
A7A70_RS15290	COG0861	Integral membrane protein TerC family
A7A70_RS15295	COG4862	establishment of competence for transformation
A7A70_RS15300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A70_RS15310	COG1164	Oligoendopeptidase f
A7A70_RS15325	COG2346	COG2346, Truncated hemoglobins
A7A70_RS15330	COG4116	CYTH
A7A70_RS15340	COG2357	RelA SpoT domain protein
A7A70_RS15350	COG0564	pseudouridine synthase activity
A7A70_RS15365	COG0772	Belongs to the SEDS family
A7A70_RS15370	COG1216	Glycosyl transferase, family 2
A7A70_RS15410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A7A70_RS15425	COG1091	dTDP-4-dehydrorhamnose reductase activity
A7A70_RS15470	COG2153	protein acetylation
A7A70_RS15480	COG2382	esterase
A7A70_RS15495	COG5492	domain, Protein
A7A70_RS15500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A70_RS15515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A7A70_RS15515	COG0512	Glutamine amidotransferase of anthranilate synthase
A7A70_RS15550	COG1620	l-lactate permease
A7A70_RS15555	COG5634	Uncharacterized conserved protein (DUF2278)
A7A70_RS15615	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A70_RS15625	COG1476	TRANSCRIPTIONal
A7A70_RS15700	COG2226	methyltransferase
A7A70_RS15710	COG1686	Belongs to the peptidase S11 family
A7A70_RS15715	COG0681	Belongs to the peptidase S26 family
A7A70_RS15735	COG1396	sequence-specific DNA binding
A7A70_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
A7A70_RS15760	COG1176	ABC-type spermidine putrescine transport system, permease component I
A7A70_RS15765	COG1177	transmembrane transport
A7A70_RS15770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A7A70_RS15780	COG2409	Drug exporters of the RND superfamily
A7A70_RS15800	COG2340	Cysteine-rich secretory protein family
A7A70_RS15805	COG0247	lactate metabolic process
A7A70_RS15810	COG0277	FAD linked oxidase domain protein
A7A70_RS15815	COG3835	regulator
A7A70_RS15825	COG0745	RESPONSE REGULATOR receiver
A7A70_RS15830	COG5002	protein histidine kinase activity
A7A70_RS15835	COG2186	Transcriptional regulator
A7A70_RS15855	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
A7A70_RS15865	COG2116	formate transmembrane transporter activity
A7A70_RS15870	COG0861	Integral membrane protein TerC family
A7A70_RS15885	COG2030	dehydratase
A7A70_RS15905	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS15910	COG3243	poly(R)-hydroxyalkanoic acid synthase
A7A70_RS15920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7A70_RS15940	COG1840	ABC-type Fe3 transport system, periplasmic component
A7A70_RS15945	COG3842	ATPase activity
A7A70_RS15970	COG1349	DNA-binding transcription factor activity
A7A70_RS15985	COG0235	Class ii aldolase
A7A70_RS15995	COG2861	carbohydrate metabolic process
A7A70_RS16005	COG3852	Histidine kinase
A7A70_RS16010	COG1846	Transcriptional regulator
A7A70_RS16020	COG2318	DinB family
A7A70_RS16030	COG5002	protein histidine kinase activity
A7A70_RS16040	COG0720	synthase
A7A70_RS16055	COG4873	Protein conserved in bacteria
A7A70_RS16095	COG1780	Probably involved in ribonucleotide reductase function
A7A70_RS16100	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7A70_RS16105	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7A70_RS16110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7A70_RS16115	COG1725	Transcriptional regulator
A7A70_RS16120	COG1131	(ABC) transporter
A7A70_RS16130	COG1131	(ABC) transporter
A7A70_RS16135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A7A70_RS16140	COG1266	CAAX protease self-immunity
A7A70_RS16150	COG1522	sequence-specific DNA binding
A7A70_RS16160	COG1335	isochorismatase
A7A70_RS16170	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7A70_RS16175	COG2070	2-Nitropropane dioxygenase
A7A70_RS16180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A7A70_RS16190	COG1696	Membrane protein involved in D-alanine export
A7A70_RS16215	COG0716	FMN binding
A7A70_RS16250	COG0534	Mate efflux family protein
A7A70_RS16270	COG1846	Transcriptional regulator
A7A70_RS16280	COG1301	dicarboxylic acid transport
A7A70_RS16285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7A70_RS16290	COG4709	membrane
A7A70_RS16295	COG3874	Sporulation protein YtfJ
A7A70_RS16325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A70_RS16330	COG0028	Belongs to the TPP enzyme family
A7A70_RS16335	COG0440	acetolactate synthase activity
A7A70_RS16410	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7A70_RS16425	COG1183	phosphatidylcholine synthase activity
A7A70_RS16430	COG1368	sulfuric ester hydrolase activity
A7A70_RS16440	COG0019	diaminopimelate decarboxylase activity
A7A70_RS16460	COG0529	Catalyzes the synthesis of activated sulfate
A7A70_RS16465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7A70_RS16485	COG1648	precorrin-2 dehydrogenase activity
A7A70_RS16490	COG0733	neurotransmitter:sodium symporter activity
A7A70_RS16510	COG1757	Na H antiporter
A7A70_RS16525	COG4758	membrane
A7A70_RS16530	COG4585	Histidine kinase
A7A70_RS16535	COG2197	response regulator
A7A70_RS16595	COG0730	response to heat
A7A70_RS16600	COG0306	phosphate transporter
A7A70_RS16605	COG1392	Phosphate transport regulator
A7A70_RS16610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A70_RS16625	COG3852	Histidine kinase
A7A70_RS16630	COG1801	Protein of unknown function DUF72
A7A70_RS16640	COG0582	viral genome integration into host DNA
A7A70_RS16645	COG5002	protein histidine kinase activity
A7A70_RS16660	COG0392	lysyltransferase activity
A7A70_RS16660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A7A70_RS16675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A7A70_RS16680	COG1686	Belongs to the peptidase S11 family
A7A70_RS16685	COG2715	membrane protein required for spore maturation
A7A70_RS16690	COG0700	Nucleoside recognition
A7A70_RS16695	COG1187	pseudouridine synthase activity
A7A70_RS16705	COG1333	cytochrome c biogenesis protein
A7A70_RS16710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A7A70_RS16715	COG0745	RESPONSE REGULATOR receiver
A7A70_RS16720	COG5002	protein histidine kinase activity
A7A70_RS16725	COG2096	Adenosyltransferase
A7A70_RS16730	COG4942	peptidase
A7A70_RS16740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A7A70_RS16745	COG1141	Ferredoxin
A7A70_RS16755	COG0514	ATP-dependent DNA helicase (RecQ)
A7A70_RS16760	COG1266	CAAX protease self-immunity
A7A70_RS16770	COG1408	metallophosphoesterase
A7A70_RS16780	COG4862	establishment of competence for transformation
A7A70_RS16785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7A70_RS16805	COG0492	ferredoxin-NADP+ reductase activity
A7A70_RS16880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7A70_RS16895	COG0142	geranyltranstransferase activity
A7A70_RS16905	COG0142	geranyltranstransferase activity
A7A70_RS16935	COG0457	Tetratricopeptide repeat
A7A70_RS16955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7A70_RS16960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A7A70_RS16960	COG2010	Cytochrome c
A7A70_RS16965	COG4347	Protein of unknown function (DUF1405)
A7A70_RS16980	COG2738	Putative neutral zinc metallopeptidase
A7A70_RS16990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS16995	COG1694	Mazg nucleotide pyrophosphohydrolase
A7A70_RS17010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7A70_RS17015	COG0438	transferase activity, transferring glycosyl groups
A7A70_RS17075	COG3935	DnaD domain protein
A7A70_RS17080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7A70_RS17090	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7A70_RS17090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A70_RS17150	COG0116	Belongs to the methyltransferase superfamily
A7A70_RS17160	COG1199	ATP-dependent helicase activity
A7A70_RS17165	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A7A70_RS17175	COG0024	Methionine aminopeptidase
A7A70_RS17185	COG2233	PERMEase
A7A70_RS17190	COG2311	Membrane
A7A70_RS17195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
A7A70_RS17205	COG0456	acetyltransferase
A7A70_RS17240	COG0754	glutathionylspermidine amidase activity
A7A70_RS17255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A7A70_RS17280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A7A70_RS17295	COG1215	transferase activity, transferring glycosyl groups
A7A70_RS17300	COG0438	transferase activity, transferring glycosyl groups
A7A70_RS17315	COG0454	-acetyltransferase
A7A70_RS17335	COG0328	RNA-DNA hybrid ribonuclease activity
A7A70_RS17370	COG3403	YqcI/YcgG family
A7A70_RS17375	COG1280	lysine exporter protein (LysE YggA)
A7A70_RS17390	COG3162	membrane
A7A70_RS17410	COG0475	glutathione-regulated potassium exporter activity
A7A70_RS17415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7A70_RS17420	COG0789	Transcriptional regulator
A7A70_RS17420	COG4978	Transcriptional regulator
A7A70_RS17430	COG2323	membrane
A7A70_RS17435	COG1434	Gram-negative-bacterium-type cell wall biogenesis
A7A70_RS17460	COG2814	Major facilitator Superfamily
A7A70_RS17470	COG2814	Major facilitator Superfamily
A7A70_RS17490	COG1923	regulation of RNA biosynthetic process
A7A70_RS17505	COG1360	Flagellar Motor Protein
A7A70_RS17510	COG2201	protein-glutamate methylesterase activity
A7A70_RS17515	COG0643	Histidine kinase
A7A70_RS17515	COG2198	Histidine kinase
A7A70_RS17520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A70_RS17520	COG1776	CheC inhibitor of MCP methylation
A7A70_RS17535	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A7A70_RS17555	COG1256	bacterial-type flagellum assembly
A7A70_RS17560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7A70_RS17570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
A7A70_RS17585	COG1815	bacterial-type flagellum-dependent cell motility
A7A70_RS17590	COG1558	bacterial-type flagellum-dependent cell motility
A7A70_RS17600	COG1766	The M ring may be actively involved in energy transduction
A7A70_RS17605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A70_RS17615	COG1157	protein secretion by the type III secretion system
A7A70_RS17650	COG0835	chemotaxis
A7A70_RS17650	COG0784	Response regulator, receiver
A7A70_RS17670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A7A70_RS17685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A70_RS17690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A7A70_RS17690	COG1776	CheC inhibitor of MCP methylation
A7A70_RS17700	COG1338	Plays a role in the flagellum-specific transport system
A7A70_RS17705	COG1987	bacterial-type flagellum assembly
A7A70_RS17715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7A70_RS17720	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A7A70_RS17725	COG1419	protein localization to endoplasmic reticulum
A7A70_RS17730	COG4786	Flagellar basal body rod
A7A70_RS17735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7A70_RS17760	COG1309	transcriptional regulator
A7A70_RS17780	COG2329	Antibiotic biosynthesis monooxygenase
A7A70_RS17795	COG3764	Sortase (surface protein transpeptidase)
A7A70_RS17800	COG3764	Sortase (surface protein transpeptidase)
A7A70_RS17830	COG0583	DNA-binding transcription factor activity
A7A70_RS17835	COG3842	ATPase activity
A7A70_RS17840	COG1840	ABC-type Fe3 transport system, periplasmic component
A7A70_RS17850	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7A70_RS17880	COG1686	Belongs to the peptidase S11 family
A7A70_RS17890	COG0406	alpha-ribazole phosphatase activity
A7A70_RS17910	COG1846	Transcriptional regulator
A7A70_RS17920	COG0367	asparagine synthase
A7A70_RS17950	COG1802	Transcriptional regulator
A7A70_RS17955	COG0697	spore germination
A7A70_RS17960	COG0523	cobalamin synthesis protein
A7A70_RS17970	COG0701	Predicted permease
A7A70_RS17980	COG0438	transferase activity, transferring glycosyl groups
A7A70_RS17980	COG1216	Glycosyl transferase, family 2
A7A70_RS17990	COG1757	Na H antiporter
A7A70_RS17995	COG0789	Transcriptional regulator
A7A70_RS18000	COG4221	oxidoreductase activity
A7A70_RS18005	COG0114	fumarate hydratase activity
A7A70_RS18030	COG0534	Mate efflux family protein
A7A70_RS18035	COG3340	Belongs to the peptidase S51 family
A7A70_RS18055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A70_RS18075	COG2733	membrane
A7A70_RS18115	COG1131	(ABC) transporter
A7A70_RS18130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A70_RS18135	COG0528	UMP kinase activity
A7A70_RS18145	COG1027	Aspartate ammonia-lyase
A7A70_RS18150	COG0281	malic enzyme
A7A70_RS18155	COG4191	Histidine kinase
A7A70_RS18160	COG0784	Response regulator, receiver
A7A70_RS18165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7A70_RS18220	COG1051	belongs to the nudix hydrolase family
A7A70_RS18265	COG0477	Major facilitator Superfamily
A7A70_RS18270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A70_RS18280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7A70_RS18285	COG4166	transmembrane transport
A7A70_RS18290	COG2223	nitrite transmembrane transporter activity
A7A70_RS18295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7A70_RS18310	COG2244	polysaccharide biosynthetic process
A7A70_RS18315	COG0733	neurotransmitter:sodium symporter activity
A7A70_RS18325	COG5566	PFAM Mor transcription activator
A7A70_RS18330	COG2323	membrane
A7A70_RS18355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A70_RS18360	COG0028	Belongs to the TPP enzyme family
A7A70_RS18380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A7A70_RS18405	COG2814	Major facilitator Superfamily
A7A70_RS18410	COG3384	dioxygenase
A7A70_RS18420	COG3279	Response regulator of the LytR AlgR family
A7A70_RS18445	COG1073	alpha beta
A7A70_RS18450	COG4166	transmembrane transport
A7A70_RS18475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS18495	COG1914	H( )-stimulated, divalent metal cation uptake system
A7A70_RS18510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7A70_RS18520	COG0531	amino acid
A7A70_RS18555	COG1309	transcriptional regulator
A7A70_RS18560	COG2390	Transcriptional regulator
A7A70_RS18570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS18575	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A7A70_RS18590	COG4846	Membrane protein involved in cytochrome C biogenesis
A7A70_RS18600	COG0006	proline dipeptidase activity
A7A70_RS18605	COG2132	Multicopper oxidase
A7A70_RS18615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7A70_RS18650	COG1276	copper resistance
A7A70_RS18650	COG2372	response to copper ion
A7A70_RS18655	COG4549	nuclear export factor GLE1
A7A70_RS18660	COG0697	spore germination
A7A70_RS18665	COG0583	DNA-binding transcription factor activity
A7A70_RS18670	COG1959	2 iron, 2 sulfur cluster binding
A7A70_RS18675	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A7A70_RS18680	COG0778	Nitroreductase
A7A70_RS18695	COG0628	permease
A7A70_RS18705	COG1231	oxidoreductase activity
A7A70_RS18715	COG0523	cobalamin synthesis protein
A7A70_RS18725	COG0318	PFAM AMP-dependent synthetase and ligase
A7A70_RS18730	COG2030	dehydratase
A7A70_RS18735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7A70_RS18750	COG0411	ABC transporter
A7A70_RS18770	COG0583	DNA-binding transcription factor activity
A7A70_RS18800	COG1271	oxidase subunit
A7A70_RS18805	COG1294	oxidase, subunit
A7A70_RS18810	COG4988	ABC transporter
A7A70_RS18815	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A7A70_RS18825	COG1216	Glycosyl transferase, family 2
A7A70_RS18855	COG1686	Belongs to the peptidase S11 family
A7A70_RS18870	COG0791	NLP P60 protein
A7A70_RS18870	COG1388	LysM domain
A7A70_RS18880	COG1132	(ABC) transporter
A7A70_RS18885	COG0745	RESPONSE REGULATOR receiver
A7A70_RS18890	COG5002	protein histidine kinase activity
A7A70_RS18900	COG0300	oxidoreductase activity
A7A70_RS18905	COG4122	O-methyltransferase activity
A7A70_RS18940	COG0460	homoserine dehydrogenase
A7A70_RS18965	COG1316	TRANSCRIPTIONal
A7A70_RS18975	COG0745	RESPONSE REGULATOR receiver
A7A70_RS18980	COG5002	protein histidine kinase activity
A7A70_RS18995	COG1285	pathogenesis
A7A70_RS19000	COG1247	-acetyltransferase
A7A70_RS19020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A70_RS19030	COG1082	Xylose isomerase domain protein TIM barrel
A7A70_RS19040	COG2814	Major facilitator Superfamily
A7A70_RS19045	COG1279	arginine transmembrane transporter activity
A7A70_RS19050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS19060	COG1752	Esterase of the alpha-beta hydrolase superfamily
A7A70_RS19100	COG0577	efflux transmembrane transporter activity
A7A70_RS19105	COG2002	toxin-antitoxin pair type II binding
A7A70_RS19110	COG1404	Belongs to the peptidase S8 family
A7A70_RS19115	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A7A70_RS19120	COG0640	Transcriptional regulator
A7A70_RS19125	COG0667	Aldo Keto reductase
A7A70_RS19180	COG3949	Membrane
A7A70_RS19185	COG3949	Membrane
A7A70_RS19190	COG0783	Belongs to the Dps family
A7A70_RS19205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A70_RS19215	COG1231	oxidoreductase activity
A7A70_RS19220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS19225	COG4989	oxidoreductase activity
A7A70_RS19230	COG0523	cobalamin synthesis protein
A7A70_RS19250	COG0803	Belongs to the bacterial solute-binding protein 9 family
A7A70_RS19250	COG3443	Belongs to the bacterial solute-binding protein 9 family
A7A70_RS19260	COG0702	epimerase
A7A70_RS19270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A7A70_RS19280	COG4166	transmembrane transport
A7A70_RS19295	COG0406	alpha-ribazole phosphatase activity
A7A70_RS19305	COG5337	Spore coat protein CotH
A7A70_RS19310	COG1051	belongs to the nudix hydrolase family
A7A70_RS19315	COG0586	Pfam SNARE associated Golgi protein
A7A70_RS19320	COG2244	polysaccharide biosynthetic process
A7A70_RS19330	COG0701	Predicted permease
A7A70_RS19335	COG3689	TIGRFAM TIGR03943 family protein
A7A70_RS19340	COG1607	acyl-coa hydrolase
A7A70_RS19350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A7A70_RS19365	COG0702	epimerase
A7A70_RS19370	COG2839	Protein conserved in bacteria
A7A70_RS19375	COG1253	flavin adenine dinucleotide binding
A7A70_RS19390	COG1114	Component of the transport system for branched-chain amino acids
A7A70_RS19395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7A70_RS19415	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS19425	COG1876	peptidase activity
A7A70_RS19435	COG0154	amidase activity
A7A70_RS19440	COG2211	Major facilitator Superfamily
A7A70_RS19460	COG0561	phosphatase activity
A7A70_RS19470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A7A70_RS19475	COG4106	trans-aconitate 2-methyltransferase activity
A7A70_RS19490	COG1819	glycosyl
A7A70_RS19495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS19500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS19530	COG0456	acetyltransferase
A7A70_RS19565	COG3874	Sporulation protein YtfJ
A7A70_RS19590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7A70_RS19610	COG0346	lactoylglutathione lyase activity
A7A70_RS19620	COG0604	alcohol dehydrogenase
A7A70_RS19625	COG1595	DNA-templated transcription, initiation
A7A70_RS19655	COG0386	Belongs to the glutathione peroxidase family
A7A70_RS19660	COG1305	Transglutaminase-like
A7A70_RS19670	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A7A70_RS19675	COG0714	Associated with various cellular activities
A7A70_RS19680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
A7A70_RS19685	COG1140	nitrate reductase beta subunit
A7A70_RS19690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
A7A70_RS19695	COG2181	nitrate reductase activity
A7A70_RS19705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7A70_RS19710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7A70_RS19715	COG0303	'Molybdopterin
A7A70_RS19720	COG0314	molybdopterin synthase activity
A7A70_RS19730	COG2223	nitrite transmembrane transporter activity
A7A70_RS19745	COG1648	precorrin-2 dehydrogenase activity
A7A70_RS19755	COG1587	Uroporphyrinogen-III synthase
A7A70_RS19755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A7A70_RS19760	COG2146	nitrite reductase [NAD(P)H] activity
A7A70_RS19765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7A70_RS19770	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
A7A70_RS19795	COG2359	stage V sporulation protein S
A7A70_RS19810	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS19825	COG1418	mRNA catabolic process
A7A70_RS19830	COG0488	(ABC) transporter
A7A70_RS19845	COG0629	single-stranded DNA binding
A7A70_RS19850	COG1413	lyase activity
A7A70_RS19865	COG2521	methyltransferase
A7A70_RS19865	COG2136	Putative SAM-dependent methyltransferase
A7A70_RS19870	COG0018	arginyl-trna synthetase
A7A70_RS19910	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A7A70_RS19920	COG0017	Asparaginyl-tRNA synthetase
A7A70_RS19940	COG1674	ftsk spoiiie
A7A70_RS20030	COG0733	neurotransmitter:sodium symporter activity
A7A70_RS20055	COG2610	gluconate transmembrane transporter activity
A7A70_RS20060	COG1454	alcohol dehydrogenase
A7A70_RS20065	COG1794	racemase activity, acting on amino acids and derivatives
A7A70_RS20075	COG0456	acetyltransferase
A7A70_RS20080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
A7A70_RS20090	COG1131	(ABC) transporter
A7A70_RS20095	COG4473	ABC transporter
A7A70_RS20105	COG0546	phosphoglycolate phosphatase activity
A7A70_RS20120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A70_RS20135	COG0768	penicillin binding
A7A70_RS20150	COG0204	Acyl-transferase
A7A70_RS20155	COG1272	protein, Hemolysin III
A7A70_RS20165	COG0805	protein transport
A7A70_RS20175	COG1307	EDD domain protein, DegV family
A7A70_RS20180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7A70_RS20185	COG1999	signal sequence binding
A7A70_RS20190	COG0071	Belongs to the small heat shock protein (HSP20) family
A7A70_RS20195	COG0367	asparagine synthase
A7A70_RS20215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS20220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A7A70_RS20235	COG1335	isochorismatase
A7A70_RS20240	COG1051	belongs to the nudix hydrolase family
A7A70_RS20245	COG0071	Belongs to the small heat shock protein (HSP20) family
A7A70_RS20250	COG0668	transmembrane transport
A7A70_RS20255	COG4585	Histidine kinase
A7A70_RS20255	COG2203	Gaf domain
A7A70_RS20260	COG2197	response regulator
A7A70_RS20265	COG1737	Transcriptional regulator
A7A70_RS20275	COG1064	alcohol dehydrogenase
A7A70_RS20300	COG1070	Carbohydrate kinase
A7A70_RS20305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A7A70_RS20345	COG1125	glycine betaine transport
A7A70_RS20345	COG0517	IMP dehydrogenase activity
A7A70_RS20350	COG1174	glycine betaine transport
A7A70_RS20395	COG5506	Protein of unknown function (DUF1694)
A7A70_RS20410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7A70_RS20415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A7A70_RS20420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A7A70_RS20425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7A70_RS20430	COG0456	acetyltransferase
A7A70_RS20435	COG3829	transcription factor binding
A7A70_RS20440	COG1509	lysine 2,3-aminomutase activity
A7A70_RS20475	COG3064	Membrane
A7A70_RS20475	COG4991	sh3 domain protein
A7A70_RS20475	COG0515	serine threonine protein kinase
A7A70_RS20480	COG4326	sporulation control protein
A7A70_RS20485	COG0671	phosphoesterase, PA-phosphatase related
A7A70_RS20490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7A70_RS20495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A70_RS20545	COG1595	DNA-templated transcription, initiation
A7A70_RS20585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A7A70_RS20620	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS20640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A7A70_RS20640	COG4499	WXG100 protein secretion system (Wss), protein YukC
A7A70_RS20650	COG2814	Major facilitator Superfamily
A7A70_RS20655	COG4841	protein insertion into membrane
A7A70_RS20660	COG0372	Belongs to the citrate synthase family
A7A70_RS20665	COG2079	MmgE PrpD family protein
A7A70_RS20670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
A7A70_RS20675	COG1960	acyl-CoA dehydrogenase activity
A7A70_RS20680	COG2084	Dehydrogenase
A7A70_RS20690	COG1280	lysine exporter protein (LysE YggA)
A7A70_RS20695	COG1024	Enoyl-CoA hydratase
A7A70_RS20710	COG0420	3'-5' exonuclease activity
A7A70_RS20740	COG2223	nitrite transmembrane transporter activity
A7A70_RS20745	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS20750	COG1169	isochorismate synthase
A7A70_RS20755	COG1021	2,3-dihydroxybenzoate-AMP ligase
A7A70_RS20760	COG1535	isochorismatase
A7A70_RS20760	COG3433	isochorismatase activity
A7A70_RS20765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A7A70_RS20770	COG3251	PFAM MbtH domain protein
A7A70_RS20775	COG2814	Major facilitator Superfamily
A7A70_RS20790	COG0776	regulation of translation
A7A70_RS20800	COG2318	DinB family
A7A70_RS20810	COG1115	amino acid carrier protein
A7A70_RS20825	COG2329	Antibiotic biosynthesis monooxygenase
A7A70_RS20830	COG1187	pseudouridine synthase activity
A7A70_RS20835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7A70_RS20845	COG1136	(ABC) transporter
A7A70_RS20875	COG0028	Belongs to the TPP enzyme family
A7A70_RS20885	COG2226	methyltransferase
A7A70_RS20920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7A70_RS20935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS20970	COG1247	-acetyltransferase
A7A70_RS20995	COG0596	Alpha beta hydrolase
A7A70_RS21000	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
A7A70_RS21010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS21020	COG1278	Cold shock
A7A70_RS21035	COG0010	Belongs to the arginase family
A7A70_RS21040	COG0561	phosphatase activity
A7A70_RS21050	COG0583	DNA-binding transcription factor activity
A7A70_RS21055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A7A70_RS21070	COG0583	DNA-binding transcription factor activity
A7A70_RS21075	COG2258	MOSC domain
A7A70_RS21090	COG1132	(ABC) transporter
A7A70_RS21095	COG1132	(ABC) transporter
A7A70_RS21100	COG0582	viral genome integration into host DNA
A7A70_RS21145	COG1484	DNA-dependent DNA replication
A7A70_RS21210	COG0582	viral genome integration into host DNA
A7A70_RS21260	COG4626	Terminase
A7A70_RS21260	COG1802	Transcriptional regulator
A7A70_RS21270	COG0740	serine-type endopeptidase activity
A7A70_RS21370	COG1396	sequence-specific DNA binding
A7A70_RS21400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A7A70_RS21410	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
A7A70_RS21415	COG1595	DNA-templated transcription, initiation
A7A70_RS21440	COG1649	PFAM Uncharacterised BCR, COG1649
A7A70_RS21465	COG2971	BadF BadG BcrA BcrD
A7A70_RS21475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7A70_RS21495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS21540	COG1309	transcriptional regulator
A7A70_RS21555	COG1136	(ABC) transporter
A7A70_RS21555	COG0577	efflux transmembrane transporter activity
A7A70_RS21560	COG3615	Tellurite resistance protein tehB
A7A70_RS21560	COG0500	methyltransferase
A7A70_RS21570	COG2226	methyltransferase
A7A70_RS21575	COG3961	Belongs to the TPP enzyme family
A7A70_RS21580	COG1846	Transcriptional regulator
A7A70_RS21610	COG2195	Cleaves the N-terminal amino acid of tripeptides
A7A70_RS21625	COG0110	maltose O-acetyltransferase activity
A7A70_RS21635	COG0768	penicillin binding
A7A70_RS21640	COG1595	DNA-templated transcription, initiation
A7A70_RS21650	COG0768	penicillin binding
A7A70_RS21655	COG0768	penicillin binding
A7A70_RS21660	COG2367	Beta-lactamase
A7A70_RS21680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS21735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS21770	COG1131	(ABC) transporter
A7A70_RS21780	COG1309	transcriptional regulator
A7A70_RS21795	COG1960	acyl-CoA dehydrogenase activity
A7A70_RS21800	COG0439	Biotin carboxylase
A7A70_RS21805	COG0511	ligase activity, forming carbon-carbon bonds
A7A70_RS21810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A7A70_RS21815	COG1024	Enoyl-CoA hydratase
A7A70_RS21820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7A70_RS21825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7A70_RS21850	COG0572	uridine kinase
A7A70_RS21860	COG2318	DinB family
A7A70_RS21865	COG1686	Belongs to the peptidase S11 family
A7A70_RS21895	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A7A70_RS21915	COG3227	Zinc metalloprotease (Elastase)
A7A70_RS21930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A7A70_RS21955	COG2814	Major facilitator Superfamily
A7A70_RS21965	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS21970	COG1733	regulation of RNA biosynthetic process
A7A70_RS21975	COG2226	methyltransferase
A7A70_RS21990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A7A70_RS22005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS22015	COG2368	4-hydroxyphenylacetate
A7A70_RS22040	COG2323	membrane
A7A70_RS22050	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A7A70_RS22065	COG3773	Cell wall hydrolase
A7A70_RS22075	COG0745	RESPONSE REGULATOR receiver
A7A70_RS22080	COG2205	protein histidine kinase activity
A7A70_RS22095	COG0488	(ABC) transporter
A7A70_RS22110	COG1136	(ABC) transporter
A7A70_RS22115	COG0577	efflux transmembrane transporter activity
A7A70_RS22135	COG0460	homoserine dehydrogenase
A7A70_RS22140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS22150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A7A70_RS22210	COG2124	cytochrome p450
A7A70_RS22245	COG0561	phosphatase activity
A7A70_RS22250	COG5002	protein histidine kinase activity
A7A70_RS22255	COG1819	glycosyl
A7A70_RS22260	COG1794	racemase activity, acting on amino acids and derivatives
A7A70_RS22285	COG2205	protein histidine kinase activity
A7A70_RS22295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A7A70_RS22300	COG0604	alcohol dehydrogenase
A7A70_RS22305	COG0671	phosphoesterase, PA-phosphatase related
A7A70_RS22310	COG0768	penicillin binding
A7A70_RS22320	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS22370	COG0693	protein deglycase activity
A7A70_RS22400	COG0584	glycerophosphoryl diester phosphodiesterase
A7A70_RS22415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS22420	COG0697	spore germination
A7A70_RS22450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A70_RS22460	COG2223	nitrite transmembrane transporter activity
A7A70_RS22475	COG2816	NAD+ diphosphatase activity
A7A70_RS22480	COG0592	DNA-directed DNA polymerase activity
A7A70_RS22485	COG1051	belongs to the nudix hydrolase family
A7A70_RS22515	COG3878	Protein conserved in bacteria
A7A70_RS22540	COG4667	esterase of the alpha-beta hydrolase superfamily
A7A70_RS22580	COG0322	excinuclease ABC activity
A7A70_RS22625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A70_RS22650	COG1011	Hydrolase
A7A70_RS22670	COG1523	belongs to the glycosyl hydrolase 13 family
A7A70_RS22675	COG3227	Zinc metalloprotease (Elastase)
A7A70_RS22685	COG0201	protein transport
A7A70_RS22695	COG0697	spore germination
A7A70_RS22700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS22740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS22795	COG1309	transcriptional regulator
A7A70_RS22815	COG3284	Transcriptional regulator
A7A70_RS22835	COG1349	DNA-binding transcription factor activity
A7A70_RS22860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A7A70_RS22865	COG0508	dehydrogenase complex catalyzes the overall conversion of
A7A70_RS22870	COG0022	dehydrogenase e1 component
A7A70_RS22875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A7A70_RS22885	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS22890	COG0456	acetyltransferase
A7A70_RS22890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A7A70_RS22930	COG4176	ABC-type proline glycine betaine transport system permease component
A7A70_RS22965	COG2153	protein acetylation
A7A70_RS22970	COG3397	chitin binding
A7A70_RS22975	COG1819	glycosyl
A7A70_RS22995	COG2205	protein histidine kinase activity
A7A70_RS23000	COG2226	methyltransferase
A7A70_RS23005	COG2315	Protein conserved in bacteria
A7A70_RS23015	COG2333	competence protein COMEC
A7A70_RS23015	COG0658	competence protein
A7A70_RS23065	COG3973	AAA domain
A7A70_RS23080	COG2105	PFAM AIG2 family protein
A7A70_RS23085	COG0514	ATP-dependent DNA helicase (RecQ)
A7A70_RS23120	COG4637	Psort location Cytoplasmic, score
A7A70_RS23145	COG3397	chitin binding
A7A70_RS23155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A7A70_RS23160	COG1115	amino acid carrier protein
A7A70_RS23165	COG1012	belongs to the aldehyde dehydrogenase family
A7A70_RS23170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7A70_RS23180	COG3938	Belongs to the proline racemase family
A7A70_RS23185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7A70_RS23260	COG4166	transmembrane transport
A7A70_RS23270	COG4948	Mandelate Racemase Muconate Lactonizing
A7A70_RS23320	COG2936	dipeptidyl-peptidase activity
A7A70_RS23325	COG5002	protein histidine kinase activity
A7A70_RS23325	COG3850	Histidine kinase
A7A70_RS23330	COG0745	RESPONSE REGULATOR receiver
A7A70_RS23365	COG1164	Oligoendopeptidase f
A7A70_RS23375	COG1307	EDD domain protein, DegV family
A7A70_RS23425	COG2814	Major facilitator Superfamily
A7A70_RS23435	COG1664	Polymer-forming cytoskeletal
A7A70_RS23440	COG0789	Transcriptional regulator
A7A70_RS23445	COG4533	DNA binding
A7A70_RS23450	COG0477	Major facilitator Superfamily
A7A70_RS23450	COG2814	Major facilitator Superfamily
A7A70_RS23475	COG2261	transglycosylase associated protein
A7A70_RS23490	COG2226	methyltransferase
A7A70_RS23535	COG0436	Aminotransferase
A7A70_RS23540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A7A70_RS23550	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A7A70_RS23595	COG0628	permease
A7A70_RS23610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A70_RS23615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A7A70_RS23620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A7A70_RS23665	COG2746	aminoglycoside 3-N-acetyltransferase activity
A7A70_RS23690	COG0697	spore germination
A7A70_RS23695	COG2318	DinB family
A7A70_RS23725	COG0346	lactoylglutathione lyase activity
A7A70_RS23750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A70_RS23755	COG0861	Integral membrane protein TerC family
A7A70_RS23760	COG1368	sulfuric ester hydrolase activity
A7A70_RS23770	COG0488	(ABC) transporter
A7A70_RS23815	COG0582	viral genome integration into host DNA
A7A70_RS23845	COG4974	Belongs to the 'phage' integrase family
A7A70_RS23855	COG1033	growth of symbiont in host cell
A7A70_RS23855	COG2409	Drug exporters of the RND superfamily
A7A70_RS23860	COG1309	transcriptional regulator
A7A70_RS23875	COG0287	Prephenate dehydrogenase
A7A70_RS23880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7A70_RS23890	COG1605	Chorismate mutase
A7A70_RS23890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A7A70_RS23925	COG3584	3D domain protein
A7A70_RS23925	COG1388	LysM domain
A7A70_RS23950	COG1172	Belongs to the binding-protein-dependent transport system permease family
A7A70_RS23965	COG2390	Transcriptional regulator
A7A70_RS23970	COG1070	Carbohydrate kinase
A7A70_RS24005	COG2329	Antibiotic biosynthesis monooxygenase
A7A70_RS24020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A7A70_RS24035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A7A70_RS24040	COG4187	Peptidase family M20/M25/M40
A7A70_RS24045	COG1414	Transcriptional regulator
A7A70_RS24055	COG0833	amino acid
A7A70_RS24070	COG3239	Fatty acid desaturase
A7A70_RS24080	COG1785	Belongs to the alkaline phosphatase family
A7A70_RS24090	COG3655	Transcriptional regulator
A7A70_RS24105	COG4377	Putative membrane peptidase family (DUF2324)
A7A70_RS24115	COG3279	Response regulator of the LytR AlgR family
A7A70_RS24130	COG0346	lactoylglutathione lyase activity
A7A70_RS24155	COG0714	Associated with various cellular activities
A7A70_RS24175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A7A70_RS24180	COG0753	catalase activity
A7A70_RS24195	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A7A70_RS24220	COG0714	Associated with various cellular activities
A7A70_RS24230	COG0778	Nitroreductase
A7A70_RS24235	COG1846	Transcriptional regulator
A7A70_RS24260	COG3831	ATPase activity
A7A70_RS24260	COG4884	unkown
A7A70_RS24265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A7A70_RS24285	COG0456	acetyltransferase
A7A70_RS24300	COG0697	spore germination
A7A70_RS24305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7A70_RS24345	COG0730	response to heat
A7A70_RS24355	COG0833	amino acid
A7A70_RS24400	COG0768	penicillin binding
A7A70_RS24440	COG1984	allophanate hydrolase subunit 2
A7A70_RS24445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7A70_RS24460	COG3142	Participates in the control of copper homeostasis
A7A70_RS24465	COG0860	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS24470	COG0640	Transcriptional regulator
A7A70_RS24480	COG1960	acyl-CoA dehydrogenase activity
A7A70_RS24495	COG3314	Sporulation integral membrane protein YlbJ
A7A70_RS24520	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
A7A70_RS24535	COG0574	Belongs to the PEP-utilizing enzyme family
A7A70_RS24535	COG3848	Pyruvate phosphate dikinase
A7A70_RS24545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS24565	COG1063	alcohol dehydrogenase
A7A70_RS24575	COG0252	asparaginase activity
A7A70_RS24580	COG1396	sequence-specific DNA binding
A7A70_RS24615	COG5002	protein histidine kinase activity
A7A70_RS24640	COG2207	Transcriptional regulator
A7A70_RS24660	COG0322	excinuclease ABC activity
A7A70_RS24665	COG0531	amino acid
A7A70_RS24680	COG0531	amino acid
A7A70_RS24685	COG0697	spore germination
A7A70_RS24690	COG0784	Response regulator, receiver
A7A70_RS24695	COG4191	Histidine kinase
A7A70_RS24700	COG2066	Belongs to the glutaminase family
A7A70_RS24705	COG1115	amino acid carrier protein
A7A70_RS24735	COG0737	Belongs to the 5'-nucleotidase family
A7A70_RS24740	COG2267	carboxylic ester hydrolase activity
A7A70_RS24745	COG1335	isochorismatase
A7A70_RS24765	COG0583	DNA-binding transcription factor activity
A7A70_RS24780	COG0598	Magnesium transport protein CorA
A7A70_RS24835	COG0415	Belongs to the DNA photolyase family
A7A70_RS24860	COG0657	acetylesterase activity
A7A70_RS24865	COG0288	reversible hydration of carbon dioxide
A7A70_RS24875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7A70_RS24880	COG5609	conserved protein (DUF2294)
A7A70_RS24895	COG0697	spore germination
A7A70_RS24905	COG1575	Belongs to the MenA family. Type 1 subfamily
A7A70_RS24910	COG4641	Protein conserved in bacteria
A7A70_RS24915	COG1136	(ABC) transporter
A7A70_RS24950	COG0798	PFAM Bile acid sodium symporter
A7A70_RS24955	COG0346	lactoylglutathione lyase activity
A7A70_RS24960	COG0640	Transcriptional regulator
A7A70_RS24975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A7A70_RS24990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A7A70_RS24990	COG3320	Male sterility
A7A70_RS24995	COG1309	transcriptional regulator
A7A70_RS25000	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS25005	COG1522	sequence-specific DNA binding
A7A70_RS25020	COG0346	lactoylglutathione lyase activity
A7A70_RS25030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A7A70_RS25055	COG2814	Major facilitator Superfamily
A7A70_RS25100	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A7A70_RS25125	COG1476	TRANSCRIPTIONal
A7A70_RS25145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A7A70_RS25165	COG0577	efflux transmembrane transporter activity
A7A70_RS25185	COG5002	protein histidine kinase activity
A7A70_RS25185	COG3850	Histidine kinase
A7A70_RS25195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS25215	COG1619	proteins homologs of microcin C7 resistance protein MccF
A7A70_RS25230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7A70_RS25250	COG0662	Cupin 2, conserved barrel domain protein
A7A70_RS25260	COG2207	Transcriptional regulator
A7A70_RS25260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS25275	COG3409	Peptidoglycan-binding domain 1 protein
A7A70_RS25275	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS25310	COG1876	peptidase activity
A7A70_RS25315	COG2843	Capsule synthesis protein
A7A70_RS25325	COG0477	Major facilitator Superfamily
A7A70_RS25340	COG1846	Transcriptional regulator
A7A70_RS25345	COG2814	Major facilitator Superfamily
A7A70_RS25355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
A7A70_RS25380	COG2076	Multidrug Resistance protein
A7A70_RS25385	COG1309	transcriptional regulator
A7A70_RS25405	COG2031	fatty acid transporter
A7A70_RS25445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7A70_RS25460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A7A70_RS25465	COG1288	antiporter activity
A7A70_RS25470	COG2356	endonuclease I
A7A70_RS25485	COG3620	sequence-specific DNA binding
A7A70_RS25500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A7A70_RS25520	COG1733	regulation of RNA biosynthetic process
A7A70_RS25525	COG0778	Nitroreductase
A7A70_RS25545	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS25555	COG1131	(ABC) transporter
A7A70_RS25580	COG1011	Hydrolase
A7A70_RS25590	COG2365	Tyrosine phosphatase family
A7A70_RS25610	COG0346	lactoylglutathione lyase activity
A7A70_RS25615	COG1940	carbohydrate kinase activity
A7A70_RS25620	COG0110	maltose O-acetyltransferase activity
A7A70_RS25635	COG0628	permease
A7A70_RS25665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A7A70_RS25675	COG0477	Major facilitator Superfamily
A7A70_RS25705	COG1253	flavin adenine dinucleotide binding
A7A70_RS25710	COG0789	Transcriptional regulator
A7A70_RS25720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A7A70_RS25745	COG0697	spore germination
A7A70_RS25750	COG1357	PFAM Pentapeptide repeats (8 copies)
A7A70_RS25755	COG3813	Protein conserved in bacteria
A7A70_RS25760	COG2706	6-phosphogluconolactonase activity
A7A70_RS25765	COG1070	Carbohydrate kinase
A7A70_RS25775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A7A70_RS25780	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A7A70_RS25790	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7A70_RS25795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A7A70_RS25800	COG0604	alcohol dehydrogenase
A7A70_RS25805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A7A70_RS25825	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS25840	COG0840	transmembrane signaling receptor activity
A7A70_RS25850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7A70_RS25850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A7A70_RS25855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7A70_RS25855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A7A70_RS25875	COG0656	L-ascorbic acid biosynthetic process
A7A70_RS25880	COG2814	Major facilitator Superfamily
A7A70_RS25895	COG0346	lactoylglutathione lyase activity
A7A70_RS25900	COG0814	amino acid
A7A70_RS25925	COG1393	Belongs to the ArsC family
A7A70_RS25930	COG1733	regulation of RNA biosynthetic process
A7A70_RS25935	COG2188	Transcriptional regulator
A7A70_RS25940	COG0673	inositol 2-dehydrogenase activity
A7A70_RS25945	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A7A70_RS25950	COG1733	regulation of RNA biosynthetic process
A7A70_RS25955	COG1733	regulation of RNA biosynthetic process
A7A70_RS25975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7A70_RS25995	COG0384	phenazine biosynthesis protein PhzF
A7A70_RS26020	COG0318	PFAM AMP-dependent synthetase and ligase
A7A70_RS26025	COG2249	NAD(P)H dehydrogenase (quinone) activity
A7A70_RS26030	COG1733	regulation of RNA biosynthetic process
A7A70_RS26065	COG1191	sigma factor activity
A7A70_RS26075	COG1280	lysine exporter protein (LysE YggA)
A7A70_RS26095	COG3152	Membrane
A7A70_RS26120	COG1151	hydroxylamine reductase activity
A7A70_RS26135	COG3409	Peptidoglycan-binding domain 1 protein
A7A70_RS26135	COG3757	hydrolase, family 25
A7A70_RS26175	COG2072	flavoprotein involved in K transport
A7A70_RS26215	COG1113	amino acid transport
A7A70_RS26220	COG2814	Major facilitator Superfamily
A7A70_RS26250	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A7A70_RS26255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7A70_RS26270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7A70_RS26275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS26280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS26285	COG3739	integral membrane protein
A7A70_RS26305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7A70_RS26320	COG0583	DNA-binding transcription factor activity
A7A70_RS26340	COG1193	negative regulation of DNA recombination
A7A70_RS26360	COG2162	N-hydroxyarylamine O-acetyltransferase activity
A7A70_RS26365	COG1164	Oligoendopeptidase f
A7A70_RS26390	COG3781	membrane
A7A70_RS26445	COG0640	Transcriptional regulator
A7A70_RS26450	COG0604	alcohol dehydrogenase
A7A70_RS26460	COG0457	Tetratricopeptide repeat
A7A70_RS26470	COG2808	Putative FMN-binding domain
A7A70_RS26475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A7A70_RS26485	COG0385	Bile acid
A7A70_RS26490	COG0277	FAD linked oxidase domain protein
A7A70_RS26500	COG0825	malonyl-CoA metabolic process
A7A70_RS26520	COG1309	transcriptional regulator
A7A70_RS26550	COG3852	Histidine kinase
A7A70_RS26560	COG1285	pathogenesis
A7A70_RS26580	COG2514	catechol 2,3-dioxygenase activity
A7A70_RS26585	COG2720	vancomycin resistance protein
A7A70_RS26625	COG0716	FMN binding
A7A70_RS26635	COG0494	nUDIX hydrolase
A7A70_RS26655	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS26665	COG0165	Argininosuccinate lyase
A7A70_RS26680	COG4145	pantothenate transmembrane transporter activity
A7A70_RS26690	COG1012	belongs to the aldehyde dehydrogenase family
A7A70_RS26695	COG1028	Short-chain dehydrogenase reductase Sdr
A7A70_RS26705	COG1657	PFAM Prenyltransferase squalene oxidase
A7A70_RS26710	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
A7A70_RS26715	COG2962	Rard protein
A7A70_RS26720	COG3326	Membrane
A7A70_RS26735	COG0489	protein tyrosine kinase activity
A7A70_RS26745	COG0314	molybdopterin synthase activity
A7A70_RS26750	COG0303	'Molybdopterin
A7A70_RS26755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7A70_RS26760	COG2116	formate transmembrane transporter activity
A7A70_RS26770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7A70_RS26775	COG5609	conserved protein (DUF2294)
A7A70_RS26780	COG2427	Protein of unknown function (DUF1641)
A7A70_RS26785	COG3383	formate dehydrogenase (NAD+) activity
A7A70_RS26795	COG0697	spore germination
A7A70_RS26810	COG0531	amino acid
A7A70_RS26845	COG2226	methyltransferase
A7A70_RS26850	COG4166	transmembrane transport
A7A70_RS26855	COG4166	transmembrane transport
A7A70_RS26860	COG4166	transmembrane transport
A7A70_RS26865	COG1301	dicarboxylic acid transport
A7A70_RS26870	COG1316	TRANSCRIPTIONal
A7A70_RS26880	COG1595	DNA-templated transcription, initiation
A7A70_RS26895	COG1131	(ABC) transporter
A7A70_RS26915	COG0673	inositol 2-dehydrogenase activity
A7A70_RS26920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A7A70_RS26925	COG0187	DNA topoisomerase II activity
A7A70_RS26930	COG1832	CoA-binding protein
A7A70_RS26935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7A70_RS26940	COG0745	RESPONSE REGULATOR receiver
A7A70_RS26960	COG4841	protein insertion into membrane
A7A70_RS26965	COG0824	Thioesterase
A7A70_RS26995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A7A70_RS27005	COG2274	protein secretion by the type I secretion system
A7A70_RS27010	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A7A70_RS27040	COG2211	Major facilitator Superfamily
A7A70_RS27050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7A70_RS27065	COG0183	Belongs to the thiolase family
A7A70_RS27070	COG0318	PFAM AMP-dependent synthetase and ligase
A7A70_RS27075	COG1268	BioY protein
A7A70_RS27080	COG0318	PFAM AMP-dependent synthetase and ligase
A7A70_RS27095	COG1396	sequence-specific DNA binding
A7A70_RS27155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A7A70_RS27170	COG5002	protein histidine kinase activity
A7A70_RS27175	COG0400	carboxylic ester hydrolase activity
A7A70_RS27180	COG0346	lactoylglutathione lyase activity
A7A70_RS27185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7A70_RS27195	COG0069	glutamate synthase activity
A7A70_RS27200	COG1902	pentaerythritol trinitrate reductase activity
A7A70_RS27205	COG1329	Transcriptional regulator
A7A70_RS27210	COG0010	Belongs to the arginase family
A7A70_RS27235	COG2226	methyltransferase
A7A70_RS27265	COG4846	Membrane protein involved in cytochrome C biogenesis
A7A70_RS27270	COG0785	Cytochrome C biogenesis protein
A7A70_RS27285	COG1473	amidohydrolase
A7A70_RS27295	COG1131	(ABC) transporter
A7A70_RS27305	COG0583	DNA-binding transcription factor activity
A7A70_RS27315	COG1346	cytolysis
A7A70_RS27330	COG0730	response to heat
A7A70_RS27340	COG3409	Peptidoglycan-binding domain 1 protein
A7A70_RS27340	COG5632	N-Acetylmuramoyl-L-alanine amidase
A7A70_RS27355	COG1132	(ABC) transporter
A7A70_RS27360	COG1132	(ABC) transporter
A7A70_RS27390	COG3639	organic phosphonate transmembrane transporter activity
A7A70_RS27400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A7A70_RS27405	COG0737	Belongs to the 5'-nucleotidase family
A7A70_RS27415	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A7A70_RS27435	COG1695	Transcriptional regulator
A7A70_RS27465	COG0174	glutamine synthetase
A7A70_RS27470	COG0789	Transcriptional regulator
A7A70_RS27475	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
A7A70_RS27480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7A70_RS27485	COG2860	membrane
A7A70_RS27490	COG0464	growth
A7A70_RS27530	COG1349	DNA-binding transcription factor activity
A7A70_RS27645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7A70_RS27735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A70_RS27735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A7A70_RS27735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A7A70_RS28095	COG0612	Peptidase, M16
A7A70_RS28110	COG3845	ABC transporter
A7A70_RS28130	COG1674	ftsk spoiiie
A7A70_RS28325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7A70_RS28335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A7A70_RS28450	COG0515	serine threonine protein kinase
A7A70_RS28450	COG2815	serine threonine protein kinase
A7A70_RS28515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A7A70_RS28690	COG1191	sigma factor activity
A7A70_RS28795	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A7A70_RS29370	COG0598	Magnesium transport protein CorA
A7A70_RS29500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A7A70_RS29520	COG0737	Belongs to the 5'-nucleotidase family
A7A70_RS29665	COG0772	Belongs to the SEDS family
A7A70_RS29735	COG0750	zinc metalloprotease