locus-tag	class	description
BC0002	COG0592	DNA-directed DNA polymerase activity
BC0003	COG2501	S4 domain
BC0005	COG0187	DNA topoisomerase II activity
BC0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC0013	COG0517	IMP dehydrogenase activity
BC0013	COG0516	GMP reductase activity
BC0014	COG1686	Belongs to the peptidase S11 family
BC0021	COG1428	Deoxynucleoside kinase
BC0022	COG1335	isochorismatase
BC0023	COG0590	tRNA wobble adenosine to inosine editing
BC0024	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BC0035	COG1982	Orn Lys Arg decarboxylase major
BC0037	COG0470	DNA polymerase III
BC0038	COG1774	PSP1 C-terminal conserved region
BC0040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BC0041	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BC0042	COG2002	toxin-antitoxin pair type II binding
BC0044	COG0084	hydrolase, TatD family'
BC0048	COG4466	Protein conserved in bacteria
BC0051	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BC0052	COG0251	oxidation-reduction process
BC0058	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BC0059	COG2002	toxin-antitoxin pair type II binding
BC0060	COG2244	polysaccharide biosynthetic process
BC0061	COG3956	TIGRFAM MazG family protein
BC0062	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BC0066	COG1098	S1 RNA binding domain
BC0069	COG2208	phosphoserine phosphatase activity
BC0071	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BC0072	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BC0075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC0076	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BC0077	COG0512	Glutamine amidotransferase of anthranilate synthase
BC0078	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC0079	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BC0080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BC0081	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BC0082	COG1396	sequence-specific DNA binding
BC0083	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC0100	COG3880	PFAM UvrB UvrC protein
BC0102	COG0542	response to heat
BC0103	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BC0105	COG4956	integral membrane protein (PIN domain superfamily)
BC0109	COG1045	serine acetyltransferase
BC0112	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC0113	COG3688	RNA-binding protein containing a PIN domain
BC0115	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC0116	COG0250	Participates in transcription elongation, termination and antitermination
BC0121	COG2813	Specifically methylates the guanine in position
BC0124	COG1358	cellular component organization or biogenesis
BC0125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BC0153	COG0024	Methionine aminopeptidase
BC0155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BC0162	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BC0167	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC0168	COG0489	protein tyrosine kinase activity
BC0170	COG2194	sulfuric ester hydrolase activity
BC0171	COG0726	polysaccharide deacetylase
BC0186	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BC0187	COG4856	YbbR-like protein
BC0195	COG1028	Short-chain dehydrogenase reductase Sdr
BC0196	COG2011	ABC-type metal ion transport system permease component
BC0198	COG1464	Belongs to the NlpA lipoprotein family
BC0199	COG0604	alcohol dehydrogenase
BC0201	COG0277	FAD linked oxidase domain protein
BC0202	COG2271	Major facilitator Superfamily
BC0204	COG2814	Major facilitator Superfamily
BC0207	COG0601	transmembrane transport
BC0208	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC0209	COG0444	Belongs to the ABC transporter superfamily
BC0210	COG4608	Belongs to the ABC transporter superfamily
BC0211	COG4166	transmembrane transport
BC0213	COG2207	Transcriptional regulator
BC0215	COG4166	transmembrane transport
BC0216	COG4166	transmembrane transport
BC0217	COG0656	L-ascorbic acid biosynthetic process
BC0220	COG4149	molybdate abc transporter
BC0221	COG0725	ABC transporter, periplasmic molybdate-binding protein
BC0222	COG1910	domain protein
BC0225	COG0697	spore germination
BC0228	COG0204	Acyl-transferase
BC0230	COG1609	Transcriptional regulator
BC0232	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC0235	COG5298	Protein conserved in bacteria
BC0239	COG0488	(ABC) transporter
BC0241	COG0747	negative chemotaxis
BC0242	COG0601	transmembrane transport
BC0243	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC0244	COG0444	Belongs to the ABC transporter superfamily
BC0245	COG4608	Belongs to the ABC transporter superfamily
BC0246	COG0561	phosphatase activity
BC0252	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BC0253	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC0255	COG0531	amino acid
BC0256	COG2814	Major facilitator Superfamily
BC0258	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BC0260	COG4294	response to UV
BC0261	COG0705	Rhomboid family
BC0263	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BC0264	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC0265	COG0864	Transcriptional regulator
BC0266	COG2337	Toxic component of a toxin-antitoxin (TA) module
BC0267	COG2183	response to ionizing radiation
BC0286	COG0802	atpase or kinase
BC0287	COG1214	PFAM Peptidase M22, glycoprotease
BC0288	COG0456	acetyltransferase
BC0290	COG0488	(ABC) transporter
BC0293	COG1266	CAAX protease self-immunity
BC0297	COG2252	PERMEase
BC0299	COG5002	protein histidine kinase activity
BC0304	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC0310	COG2226	methyltransferase
BC0312	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC0314	COG1215	transferase activity, transferring glycosyl groups
BC0318	COG0697	spore germination
BC0323	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BC0324	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BC0325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BC0327	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BC0330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BC0332	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BC0334	COG0151	Belongs to the GarS family
BC0340	COG0210	DNA helicase
BC0342	COG4851	CamS sex pheromone cAM373 precursor
BC0345	COG1335	isochorismatase
BC0347	COG2011	ABC-type metal ion transport system permease component
BC0348	COG1464	Belongs to the NlpA lipoprotein family
BC0349	COG4682	membrane
BC0353	COG1597	lipid kinase activity
BC0355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BC0357	COG1012	belongs to the aldehyde dehydrogenase family
BC0358	COG2076	Multidrug Resistance protein
BC0360	COG2309	aminopeptidase activity
BC0363	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC0365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BC0368	COG4807	Protein conserved in bacteria
BC0373	COG1757	Na H antiporter
BC0374	COG1473	amidohydrolase
BC0377	COG0450	alkyl hydroperoxide reductase
BC0381	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC0382	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC0383	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC0385	COG0492	ferredoxin-NADP+ reductase activity
BC0388	COG0166	Belongs to the GPI family
BC0393	COG5002	protein histidine kinase activity
BC0397	COG3541	Predicted nucleotidyltransferase
BC0398	COG2814	Major facilitator Superfamily
BC0399	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC0399	COG0723	plastoquinol--plastocyanin reductase activity
BC0401	COG0765	amino acid transport
BC0402	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC0403	COG1126	abc transporter atp-binding protein
BC0404	COG0840	transmembrane signaling receptor activity
BC0409	COG0549	Belongs to the carbamate kinase family
BC0410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC0412	COG0277	FAD linked oxidase domain protein
BC0413	COG0366	Alpha amylase catalytic
BC0414	COG1263	PTS System
BC0414	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC0414	COG2190	(PTS) system
BC0421	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BC0425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC0426	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC0427	COG1116	anion transmembrane transporter activity
BC0428	COG0488	(ABC) transporter
BC0436	COG2270	Major facilitator Superfamily
BC0442	COG2310	stress, protein
BC0443	COG2310	stress, protein
BC0444	COG2310	stress, protein
BC0445	COG0861	Integral membrane protein TerC family
BC0447	COG3853	Toxic anion resistance protein (TelA)
BC0450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BC0452	COG1295	ribonuclease BN
BC0453	COG2217	Heavy metal translocating P-type atpase
BC0454	COG0697	spore germination
BC0456	COG0681	Belongs to the peptidase S26 family
BC0458	COG0586	Pfam SNARE associated Golgi protein
BC0461	COG3871	stress protein (general stress protein 26)
BC0462	COG0387	Pfam Sodium calcium exchanger
BC0464	COG0535	radical SAM domain protein
BC0468	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BC0473	COG3829	transcription factor binding
BC0476	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC0482	COG1263	PTS System
BC0482	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC0483	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC0486	COG0463	Glycosyl transferase, family 2
BC0488	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC0488	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC0492	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BC0496	COG1228	amidohydrolase
BC0497	COG1090	epimerase
BC0503	COG1988	membrane-bound metal-dependent
BC0504	COG1194	a g-specific adenine glycosylase
BC0509	COG1132	(ABC) transporter
BC0510	COG4129	membrane
BC0511	COG0070	glutamate synthase
BC0511	COG0067	glutamate synthase
BC0511	COG0069	glutamate synthase activity
BC0513	COG4555	ABC transporter
BC0517	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BC0518	COG0735	belongs to the Fur family
BC0541	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BC0546	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BC0548	COG2766	serine protein kinase
BC0555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC0557	COG1585	Membrane protein implicated in regulation of membrane protease activity
BC0558	COG2268	Band 7 protein
BC0560	COG3290	protein histidine kinase activity
BC0561	COG4565	transcriptional regulatory protein
BC0562	COG2851	Citrate transporter
BC0566	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC0567	COG3842	ATPase activity
BC0568	COG1175	transmembrane transport
BC0569	COG0395	ABC-type sugar transport system, permease component
BC0571	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BC0572	COG0745	RESPONSE REGULATOR receiver
BC0573	COG5002	protein histidine kinase activity
BC0575	COG4990	cell redox homeostasis
BC0577	COG3290	protein histidine kinase activity
BC0578	COG4565	transcriptional regulatory protein
BC0579	COG3493	citrate carrier protein
BC0580	COG0281	malic enzyme
BC0582	COG0697	spore germination
BC0583	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC0585	COG5002	protein histidine kinase activity
BC0587	COG0456	acetyltransferase
BC0587	COG0454	-acetyltransferase
BC0588	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC0589	COG3383	formate dehydrogenase (NAD+) activity
BC0590	COG2427	Protein of unknown function (DUF1641)
BC0593	COG0531	amino acid
BC0595	COG0640	Transcriptional regulator
BC0596	COG2217	Heavy metal translocating P-type atpase
BC0597	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BC0602	COG3227	Zinc metalloprotease (Elastase)
BC0606	COG2720	vancomycin resistance protein
BC0607	COG1316	TRANSCRIPTIONal
BC0608	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC0609	COG0346	lactoylglutathione lyase activity
BC0610	COG1253	flavin adenine dinucleotide binding
BC0611	COG1027	Aspartate ammonia-lyase
BC0612	COG1620	l-lactate permease
BC0615	COG3104	oligopeptide transport
BC0616	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC0618	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC0622	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC0624	COG4548	von Willebrand factor, type A
BC0625	COG0714	Associated with various cellular activities
BC0629	COG0531	amino acid
BC0630	COG2188	Transcriptional regulator
BC0631	COG1263	PTS System
BC0631	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC0632	COG0366	Alpha amylase catalytic
BC0635	COG0697	spore germination
BC0637	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC0638	COG1115	amino acid carrier protein
BC0639	COG1126	abc transporter atp-binding protein
BC0640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC0641	COG0765	amino acid transport
BC0642	COG0765	amino acid transport
BC0643	COG0833	amino acid
BC0649	COG2378	regulation of single-species biofilm formation
BC0650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC0651	COG5002	protein histidine kinase activity
BC0654	COG0659	secondary active sulfate transmembrane transporter activity
BC0656	COG2271	Major facilitator Superfamily
BC0657	COG1846	Transcriptional regulator
BC0658	COG0477	Major facilitator Superfamily
BC0659	COG1609	Transcriptional regulator
BC0660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC0663	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC0668	COG1063	alcohol dehydrogenase
BC0678	COG0840	transmembrane signaling receptor activity
BC0679	COG3584	3D domain protein
BC0679	COG3583	domain protein
BC0680	COG1476	TRANSCRIPTIONal
BC0684	COG3104	oligopeptide transport
BC0685	COG1114	Component of the transport system for branched-chain amino acids
BC0688	COG1113	amino acid transport
BC0689	COG2252	PERMEase
BC0692	COG2153	protein acetylation
BC0694	COG0475	glutathione-regulated potassium exporter activity
BC0694	COG0569	domain protein
BC0697	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BC0699	COG0833	amino acid
BC0700	COG4990	cell redox homeostasis
BC0703	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC0705	COG0531	amino acid
BC0707	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC0708	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC0709	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BC0709	COG1918	ferrous iron import across plasma membrane
BC0710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC0711	COG0573	inorganic phosphate transmembrane transporter activity
BC0712	COG0581	inorganic phosphate transmembrane transporter activity
BC0714	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC0737	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BC0742	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC0743	COG1116	anion transmembrane transporter activity
BC0744	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC0745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC0746	COG0352	thiamine-phosphate diphosphorylase activity
BC0747	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC0748	COG2104	thiamine diphosphate biosynthetic process
BC0750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC0751	COG0351	phosphomethylpyrimidine kinase
BC0756	COG2205	protein histidine kinase activity
BC0757	COG2814	Major facilitator Superfamily
BC0758	COG1846	Transcriptional regulator
BC0764	COG1136	(ABC) transporter
BC0766	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC0767	COG1129	ABC transporter
BC0769	COG2252	PERMEase
BC0770	COG1028	Short-chain dehydrogenase reductase Sdr
BC0773	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BC0774	COG1621	beta-fructofuranosidase activity
BC0775	COG1263	PTS System
BC0775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC0776	COG1609	Transcriptional regulator
BC0786	COG0778	Nitroreductase
BC0787	COG2719	SpoVR family
BC0789	COG3591	Belongs to the peptidase S1B family
BC0791	COG0446	pyridine nucleotide-disulphide oxidoreductase
BC0792	COG1937	Protein conserved in bacteria
BC0793	COG0425	Belongs to the sulfur carrier protein TusA family
BC0793	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC0794	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC0794	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC0795	COG0425	Belongs to the sulfur carrier protein TusA family
BC0796	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC0796	COG0425	Belongs to the sulfur carrier protein TusA family
BC0797	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC0798	COG2210	Belongs to the sulfur carrier protein TusA family
BC0799	COG0730	response to heat
BC0801	COG1316	TRANSCRIPTIONal
BC0802	COG0604	alcohol dehydrogenase
BC0803	COG1283	sodium-dependent phosphate transmembrane transporter activity
BC0806	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC0806	COG3711	transcriptional antiterminator
BC0807	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC0808	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC0813	COG1388	LysM domain
BC0813	COG3584	3D domain protein
BC0814	COG0577	efflux transmembrane transporter activity
BC0815	COG1136	(ABC) transporter
BC0817	COG5522	Integral membrane protein (intg_mem_TP0381)
BC0820	COG1114	Component of the transport system for branched-chain amino acids
BC0821	COG3546	catalase activity
BC0828	COG0586	Pfam SNARE associated Golgi protein
BC0838	COG0475	glutathione-regulated potassium exporter activity
BC0840	COG1737	Transcriptional regulator
BC0842	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC0842	COG1263	PTS System
BC0844	COG2259	Doxx family
BC0848	COG1522	sequence-specific DNA binding
BC0849	COG0165	Argininosuccinate lyase
BC0849	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BC0850	COG1028	Short-chain dehydrogenase reductase Sdr
BC0854	COG1309	transcriptional regulator
BC0855	COG2814	Major facilitator Superfamily
BC0856	COG1733	regulation of RNA biosynthetic process
BC0859	COG4533	DNA binding
BC0860	COG2211	Major facilitator Superfamily
BC0862	COG0693	protein deglycase activity
BC0863	COG0693	protein deglycase activity
BC0863	COG0753	catalase activity
BC0865	COG0531	amino acid
BC0866	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BC0868	COG1012	belongs to the aldehyde dehydrogenase family
BC0870	COG1132	(ABC) transporter
BC0871	COG1132	(ABC) transporter
BC0872	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC0873	COG0765	amino acid transport
BC0874	COG1126	abc transporter atp-binding protein
BC0877	COG0189	ligase activity
BC0881	COG4585	Histidine kinase
BC0882	COG2197	response regulator
BC0883	COG0028	Belongs to the TPP enzyme family
BC0884	COG3527	Alpha-acetolactate decarboxylase
BC0886	COG0561	phosphatase activity
BC0888	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC0888	COG3409	Peptidoglycan-binding domain 1 protein
BC0889	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC0890	COG0318	PFAM AMP-dependent synthetase and ligase
BC0893	COG0659	secondary active sulfate transmembrane transporter activity
BC0894	COG2244	polysaccharide biosynthetic process
BC0898	COG1024	Enoyl-CoA hydratase
BC0901	COG1363	Peptidase, m42
BC0908	COG0601	transmembrane transport
BC0909	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC0910	COG0444	Belongs to the ABC transporter superfamily
BC0911	COG4608	Belongs to the ABC transporter superfamily
BC0913	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC0935	COG0477	Major facilitator Superfamily
BC0936	COG3290	protein histidine kinase activity
BC0937	COG4565	transcriptional regulatory protein
BC0938	COG3181	Tripartite tricarboxylate transporter family receptor
BC0939	COG1401	restriction endodeoxyribonuclease activity
BC0945	COG0582	viral genome integration into host DNA
BC0953	COG4978	Transcriptional regulator
BC0953	COG0789	Transcriptional regulator
BC0956	COG0305	Participates in initiation and elongation during chromosome replication
BC0962	COG0477	Major facilitator Superfamily
BC0964	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC0968	COG1073	alpha beta
BC0976	COG1183	phosphatidylcholine synthase activity
BC0979	COG2376	Dihydroxyacetone kinase
BC0981	COG2376	Dihydroxyacetone kinase
BC0986	COG0457	Tetratricopeptide repeat
BC0991	COG2373	Large extracellular alpha-helical protein
BC1004	COG1191	sigma factor activity
BC1006	COG2208	phosphoserine phosphatase activity
BC1007	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC1015	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BC1019	COG0420	3'-5' exonuclease activity
BC1020	COG4717	serine-type aminopeptidase activity
BC1023	COG1280	lysine exporter protein (LysE YggA)
BC1024	COG0346	lactoylglutathione lyase activity
BC1025	COG0346	lactoylglutathione lyase activity
BC1026	COG0457	Tetratricopeptide repeat
BC1027	COG2267	carboxylic ester hydrolase activity
BC1031	COG2140	Oxalate decarboxylase
BC1032	COG3620	sequence-specific DNA binding
BC1033	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BC1034	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BC1036	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BC1037	COG1695	Transcriptional regulator
BC1041	COG3973	AAA domain
BC1048	COG4980	gas vesicle protein
BC1049	COG0537	adenosine 5'-monophosphoramidase activity
BC1050	COG1131	(ABC) transporter
BC1051	COG4473	ABC transporter
BC1055	COG3402	PFAM membrane-flanked domain
BC1056	COG3428	Bacterial PH domain
BC1063	COG0697	spore germination
BC1064	COG3402	PFAM membrane-flanked domain
BC1065	COG3428	Bacterial PH domain
BC1066	COG2329	Antibiotic biosynthesis monooxygenase
BC1067	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC1070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BC1077	COG1309	transcriptional regulator
BC1078	COG1511	domain protein
BC1082	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC1083	COG1609	Transcriptional regulator
BC1085	COG1234	tRNA 3'-trailer cleavage
BC1086	COG0095	Lipoate-protein ligase
BC1088	COG0318	PFAM AMP-dependent synthetase and ligase
BC1093	COG4208	sulfate ABC transporter
BC1111	COG1408	metallophosphoesterase
BC1112	COG1078	dGTPase activity
BC1114	COG1595	DNA-templated transcription, initiation
BC1115	COG2207	Transcriptional regulator
BC1115	COG3708	Transcriptional regulator
BC1118	COG2205	protein histidine kinase activity
BC1119	COG0745	RESPONSE REGULATOR receiver
BC1123	COG0501	Belongs to the peptidase M48B family
BC1124	COG0840	transmembrane signaling receptor activity
BC1125	COG3693	PFAM glycoside hydrolase, family 10
BC1127	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BC1128	COG2224	Isocitrate lyase
BC1135	COG0398	Pfam SNARE associated Golgi protein
BC1147	COG0179	Fumarylacetoacetate (FAA) hydrolase
BC1155	COG0753	catalase activity
BC1156	COG0004	ammonium transporteR
BC1160	COG2996	Protein conserved in bacteria
BC1163	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC1165	COG0561	phosphatase activity
BC1170	COG2267	carboxylic ester hydrolase activity
BC1174	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BC1175	COG5504	Zn-dependent protease
BC1179	COG4166	transmembrane transport
BC1180	COG0601	transmembrane transport
BC1181	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BC1182	COG0444	Belongs to the ABC transporter superfamily
BC1183	COG4608	Belongs to the ABC transporter superfamily
BC1184	COG0534	Mate efflux family protein
BC1185	COG4166	transmembrane transport
BC1189	COG0861	Integral membrane protein TerC family
BC1193	COG1164	Oligoendopeptidase f
BC1195	COG2346	COG2346, Truncated hemoglobins
BC1196	COG4116	CYTH
BC1198	COG2357	RelA SpoT domain protein
BC1200	COG0564	pseudouridine synthase activity
BC1203	COG0772	Belongs to the SEDS family
BC1204	COG1216	Glycosyl transferase, family 2
BC1208	COG0463	Glycosyl transferase, family 2
BC1208	COG0457	Tetratricopeptide repeat
BC1212	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BC1215	COG1091	dTDP-4-dehydrorhamnose reductase activity
BC1224	COG2153	protein acetylation
BC1226	COG2382	esterase
BC1231	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC1233	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BC1233	COG0512	Glutamine amidotransferase of anthranilate synthase
BC1240	COG1620	l-lactate permease
BC1241	COG5634	Uncharacterized conserved protein (DUF2278)
BC1251	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC1253	COG1476	TRANSCRIPTIONal
BC1272	COG0582	viral genome integration into host DNA
BC1277	COG1686	Belongs to the peptidase S11 family
BC1278	COG0681	Belongs to the peptidase S26 family
BC1285	COG1012	belongs to the aldehyde dehydrogenase family
BC1287	COG1176	ABC-type spermidine putrescine transport system, permease component I
BC1288	COG1177	transmembrane transport
BC1291	COG2409	Drug exporters of the RND superfamily
BC1293	COG0564	pseudouridine synthase activity
BC1295	COG2340	Cysteine-rich secretory protein family
BC1296	COG0247	lactate metabolic process
BC1297	COG0277	FAD linked oxidase domain protein
BC1298	COG3835	regulator
BC1300	COG0745	RESPONSE REGULATOR receiver
BC1301	COG5002	protein histidine kinase activity
BC1302	COG2186	Transcriptional regulator
BC1306	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BC1308	COG2116	formate transmembrane transporter activity
BC1309	COG0861	Integral membrane protein TerC family
BC1310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC1312	COG2030	dehydratase
BC1317	COG1028	Short-chain dehydrogenase reductase Sdr
BC1318	COG3243	poly(R)-hydroxyalkanoic acid synthase
BC1320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC1323	COG1840	ABC-type Fe3 transport system, periplasmic component
BC1324	COG3842	ATPase activity
BC1329	COG1349	DNA-binding transcription factor activity
BC1334	COG2861	carbohydrate metabolic process
BC1336	COG3852	Histidine kinase
BC1337	COG1846	Transcriptional regulator
BC1339	COG2318	DinB family
BC1340	COG5002	protein histidine kinase activity
BC1342	COG0720	synthase
BC1345	COG4873	Protein conserved in bacteria
BC1353	COG1780	Probably involved in ribonucleotide reductase function
BC1354	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC1355	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BC1356	COG1725	Transcriptional regulator
BC1357	COG1131	(ABC) transporter
BC1359	COG1131	(ABC) transporter
BC1361	COG1266	CAAX protease self-immunity
BC1363	COG1522	sequence-specific DNA binding
BC1365	COG1335	isochorismatase
BC1367	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC1368	COG2070	2-Nitropropane dioxygenase
BC1369	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BC1371	COG1696	Membrane protein involved in D-alanine export
BC1376	COG0716	FMN binding
BC1387	COG1846	Transcriptional regulator
BC1389	COG1301	dicarboxylic acid transport
BC1390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BC1391	COG4709	membrane
BC1392	COG3874	Sporulation protein YtfJ
BC1396	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC1398	COG0440	acetolactate synthase activity
BC1413	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC1416	COG1183	phosphatidylcholine synthase activity
BC1417	COG1368	sulfuric ester hydrolase activity
BC1419	COG0019	diaminopimelate decarboxylase activity
BC1423	COG0529	Catalyzes the synthesis of activated sulfate
BC1424	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC1428	COG1648	precorrin-2 dehydrogenase activity
BC1430	COG0733	neurotransmitter:sodium symporter activity
BC1434	COG1757	Na H antiporter
BC1437	COG4758	membrane
BC1438	COG4585	Histidine kinase
BC1439	COG2197	response regulator
BC1441	COG1114	Component of the transport system for branched-chain amino acids
BC1452	COG0730	response to heat
BC1453	COG0306	phosphate transporter
BC1454	COG1392	Phosphate transport regulator
BC1455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC1458	COG3852	Histidine kinase
BC1459	COG1801	Protein of unknown function DUF72
BC1461	COG0582	viral genome integration into host DNA
BC1465	COG0392	lysyltransferase activity
BC1465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BC1468	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BC1469	COG1686	Belongs to the peptidase S11 family
BC1470	COG2715	membrane protein required for spore maturation
BC1471	COG0700	Nucleoside recognition
BC1472	COG1187	pseudouridine synthase activity
BC1476	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC1477	COG0745	RESPONSE REGULATOR receiver
BC1478	COG5002	protein histidine kinase activity
BC1479	COG2096	Adenosyltransferase
BC1482	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BC1483	COG1141	Ferredoxin
BC1485	COG0514	ATP-dependent DNA helicase (RecQ)
BC1486	COG1266	CAAX protease self-immunity
BC1488	COG1408	metallophosphoesterase
BC1489	COG0789	Transcriptional regulator
BC1491	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BC1495	COG0492	ferredoxin-NADP+ reductase activity
BC1496	COG0252	asparaginase activity
BC1509	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC1512	COG0142	geranyltranstransferase activity
BC1514	COG0142	geranyltranstransferase activity
BC1519	COG0457	Tetratricopeptide repeat
BC1523	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC1524	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BC1524	COG2010	Cytochrome c
BC1525	COG4347	Protein of unknown function (DUF1405)
BC1528	COG2738	Putative neutral zinc metallopeptidase
BC1530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC1531	COG1694	Mazg nucleotide pyrophosphohydrolase
BC1535	COG0438	transferase activity, transferring glycosyl groups
BC1547	COG3935	DnaD domain protein
BC1548	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BC1550	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC1550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC1553	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC1553	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC1563	COG0116	Belongs to the methyltransferase superfamily
BC1565	COG1199	ATP-dependent helicase activity
BC1566	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BC1568	COG0024	Methionine aminopeptidase
BC1570	COG2233	PERMEase
BC1571	COG2311	Membrane
BC1572	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC1574	COG0456	acetyltransferase
BC1582	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC1584	COG3944	biosynthesis protein
BC1586	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC1589	COG1215	transferase activity, transferring glycosyl groups
BC1590	COG0438	transferase activity, transferring glycosyl groups
BC1593	COG0454	-acetyltransferase
BC1597	COG0328	RNA-DNA hybrid ribonuclease activity
BC1604	COG3403	YqcI/YcgG family
BC1605	COG1280	lysine exporter protein (LysE YggA)
BC1609	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC1610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC1612	COG0475	glutathione-regulated potassium exporter activity
BC1613	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC1614	COG4978	Transcriptional regulator
BC1614	COG0789	Transcriptional regulator
BC1616	COG2323	membrane
BC1617	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BC1623	COG1923	regulation of RNA biosynthetic process
BC1625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC1626	COG1360	Flagellar Motor Protein
BC1627	COG2201	protein-glutamate methylesterase activity
BC1628	COG2198	Histidine kinase
BC1628	COG0643	Histidine kinase
BC1629	COG1776	CheC inhibitor of MCP methylation
BC1629	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC1632	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BC1636	COG1256	bacterial-type flagellum assembly
BC1637	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC1638	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BC1641	COG1815	bacterial-type flagellum-dependent cell motility
BC1642	COG1558	bacterial-type flagellum-dependent cell motility
BC1644	COG1766	The M ring may be actively involved in energy transduction
BC1645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC1647	COG1157	protein secretion by the type III secretion system
BC1654	COG0784	Response regulator, receiver
BC1654	COG0835	chemotaxis
BC1656	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC1657	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC1658	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC1659	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BC1660	COG0741	lytic transglycosylase activity
BC1662	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC1663	COG1776	CheC inhibitor of MCP methylation
BC1663	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BC1665	COG1338	Plays a role in the flagellum-specific transport system
BC1666	COG1987	bacterial-type flagellum assembly
BC1668	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BC1671	COG4786	Flagellar basal body rod
BC1672	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BC1678	COG2329	Antibiotic biosynthesis monooxygenase
BC1683	COG0583	DNA-binding transcription factor activity
BC1691	COG0406	alpha-ribazole phosphatase activity
BC1697	COG0367	asparagine synthase
BC1703	COG1802	Transcriptional regulator
BC1704	COG0697	spore germination
BC1705	COG0523	cobalamin synthesis protein
BC1706	COG0701	Predicted permease
BC1709	COG1757	Na H antiporter
BC1710	COG0789	Transcriptional regulator
BC1716	COG0534	Mate efflux family protein
BC1717	COG3340	Belongs to the peptidase S51 family
BC1721	COG0785	Cytochrome C biogenesis protein
BC1726	COG2733	membrane
BC1734	COG1131	(ABC) transporter
BC1737	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC1738	COG0528	UMP kinase activity
BC1740	COG1027	Aspartate ammonia-lyase
BC1741	COG0281	malic enzyme
BC1742	COG4191	Histidine kinase
BC1743	COG0784	Response regulator, receiver
BC1744	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC1753	COG2814	Major facilitator Superfamily
BC1756	COG1695	Transcriptional regulator
BC1759	COG0477	Major facilitator Superfamily
BC1761	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC1762	COG2223	nitrite transmembrane transporter activity
BC1763	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC1767	COG0733	neurotransmitter:sodium symporter activity
BC1769	COG5566	PFAM Mor transcription activator
BC1770	COG2323	membrane
BC1774	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC1776	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC1777	COG0028	Belongs to the TPP enzyme family
BC1781	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BC1786	COG2814	Major facilitator Superfamily
BC1787	COG3384	dioxygenase
BC1789	COG3279	Response regulator of the LytR AlgR family
BC1790	COG0427	acetyl-CoA hydrolase
BC1794	COG4166	transmembrane transport
BC1799	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC1800	COG0745	RESPONSE REGULATOR receiver
BC1803	COG1914	H( )-stimulated, divalent metal cation uptake system
BC1806	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC1807	COG0531	amino acid
BC1812	COG2309	aminopeptidase activity
BC1815	COG0456	acetyltransferase
BC1818	COG1309	transcriptional regulator
BC1819	COG2390	Transcriptional regulator
BC1821	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC1822	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BC1823	COG0295	cytidine deaminase activity
BC1824	COG2963	transposase activity
BC1825	COG2801	Transposase and inactivated derivatives
BC1826	COG4846	Membrane protein involved in cytochrome C biogenesis
BC1828	COG0006	proline dipeptidase activity
BC1830	COG2132	Multicopper oxidase
BC1832	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC1836	COG1114	Component of the transport system for branched-chain amino acids
BC1838	COG2372	response to copper ion
BC1838	COG1276	copper resistance
BC1839	COG4549	nuclear export factor GLE1
BC1840	COG0697	spore germination
BC1841	COG0583	DNA-binding transcription factor activity
BC1842	COG1959	2 iron, 2 sulfur cluster binding
BC1843	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BC1844	COG0778	Nitroreductase
BC1846	COG0154	amidase activity
BC1847	COG1396	sequence-specific DNA binding
BC1864	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC1864	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC1884	COG2002	toxin-antitoxin pair type II binding
BC1922	COG0154	amidase activity
BC1923	COG0628	permease
BC1925	COG1231	oxidoreductase activity
BC1926	COG0523	cobalamin synthesis protein
BC1928	COG0411	ABC transporter
BC1932	COG0583	DNA-binding transcription factor activity
BC1938	COG1271	oxidase subunit
BC1939	COG1294	oxidase, subunit
BC1940	COG4988	ABC transporter
BC1941	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BC1943	COG1216	Glycosyl transferase, family 2
BC1951	COG1686	Belongs to the peptidase S11 family
BC1953	COG1388	LysM domain
BC1953	COG0791	NLP P60 protein
BC1955	COG1132	(ABC) transporter
BC1956	COG0745	RESPONSE REGULATOR receiver
BC1957	COG5002	protein histidine kinase activity
BC1958	COG0300	oxidoreductase activity
BC1964	COG0460	homoserine dehydrogenase
BC1969	COG1316	TRANSCRIPTIONal
BC1972	COG0745	RESPONSE REGULATOR receiver
BC1973	COG5002	protein histidine kinase activity
BC1976	COG1285	pathogenesis
BC1977	COG1247	-acetyltransferase
BC1981	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC1983	COG1082	Xylose isomerase domain protein TIM barrel
BC1986	COG1279	arginine transmembrane transporter activity
BC1987	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC1989	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC1995	COG0577	efflux transmembrane transporter activity
BC1996	COG2002	toxin-antitoxin pair type II binding
BC1997	COG1404	Belongs to the peptidase S8 family
BC1998	COG0640	Transcriptional regulator
BC1999	COG0667	Aldo Keto reductase
BC2001	COG3152	Membrane
BC2006	COG0840	transmembrane signaling receptor activity
BC2010	COG3949	Membrane
BC2011	COG0783	Belongs to the Dps family
BC2014	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC2016	COG1231	oxidoreductase activity
BC2017	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC2018	COG4989	oxidoreductase activity
BC2019	COG0523	cobalamin synthesis protein
BC2020	COG0456	acetyltransferase
BC2021	COG0803	Belongs to the bacterial solute-binding protein 9 family
BC2022	COG0702	epimerase
BC2024	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC2026	COG4166	transmembrane transport
BC2031	COG5337	Spore coat protein CotH
BC2032	COG1051	belongs to the nudix hydrolase family
BC2033	COG0586	Pfam SNARE associated Golgi protein
BC2034	COG2244	polysaccharide biosynthetic process
BC2036	COG0701	Predicted permease
BC2037	COG3689	TIGRFAM TIGR03943 family protein
BC2038	COG1607	acyl-coa hydrolase
BC2039	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC2042	COG0702	epimerase
BC2043	COG2839	Protein conserved in bacteria
BC2044	COG1253	flavin adenine dinucleotide binding
BC2047	COG1114	Component of the transport system for branched-chain amino acids
BC2048	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC2050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC2052	COG1876	peptidase activity
BC2054	COG0154	amidase activity
BC2055	COG2211	Major facilitator Superfamily
BC2058	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC2060	COG0561	phosphatase activity
BC2063	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BC2066	COG1819	glycosyl
BC2067	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC2068	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC2074	COG0456	acetyltransferase
BC2080	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC2095	COG3874	Sporulation protein YtfJ
BC2100	COG2226	methyltransferase
BC2104	COG1082	Xylose isomerase domain protein TIM barrel
BC2105	COG0346	lactoylglutathione lyase activity
BC2107	COG0604	alcohol dehydrogenase
BC2108	COG1595	DNA-templated transcription, initiation
BC2110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BC2114	COG0386	Belongs to the glutathione peroxidase family
BC2115	COG1305	Transglutaminase-like
BC2117	COG0714	Associated with various cellular activities
BC2118	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BC2119	COG1140	nitrate reductase beta subunit
BC2120	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BC2121	COG2181	nitrate reductase activity
BC2122	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC2123	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC2124	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC2125	COG0303	'Molybdopterin
BC2126	COG0314	molybdopterin synthase activity
BC2128	COG2223	nitrite transmembrane transporter activity
BC2132	COG1648	precorrin-2 dehydrogenase activity
BC2134	COG1587	Uroporphyrinogen-III synthase
BC2134	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BC2135	COG2146	nitrite reductase [NAD(P)H] activity
BC2136	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BC2137	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BC2142	COG2359	stage V sporulation protein S
BC2147	COG0457	Tetratricopeptide repeat
BC2150	COG1418	mRNA catabolic process
BC2151	COG0488	(ABC) transporter
BC2154	COG0629	single-stranded DNA binding
BC2155	COG1413	lyase activity
BC2158	COG2521	methyltransferase
BC2158	COG2136	Putative SAM-dependent methyltransferase
BC2169	COG0017	Asparaginyl-tRNA synthetase
BC2170	COG0733	neurotransmitter:sodium symporter activity
BC2175	COG2610	gluconate transmembrane transporter activity
BC2177	COG1794	racemase activity, acting on amino acids and derivatives
BC2179	COG0456	acetyltransferase
BC2181	COG3655	Transcriptional regulator
BC2182	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BC2184	COG1131	(ABC) transporter
BC2185	COG4473	ABC transporter
BC2187	COG0546	phosphoglycolate phosphatase activity
BC2190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC2193	COG0768	penicillin binding
BC2195	COG0204	Acyl-transferase
BC2196	COG1272	protein, Hemolysin III
BC2198	COG0805	protein transport
BC2200	COG1307	EDD domain protein, DegV family
BC2202	COG1999	signal sequence binding
BC2203	COG0071	Belongs to the small heat shock protein (HSP20) family
BC2204	COG0367	asparagine synthase
BC2207	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC2208	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC2209	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BC2213	COG1335	isochorismatase
BC2215	COG0668	transmembrane transport
BC2216	COG4585	Histidine kinase
BC2216	COG2203	Gaf domain
BC2217	COG2197	response regulator
BC2218	COG1737	Transcriptional regulator
BC2219	COG0384	phenazine biosynthesis protein PhzF
BC2220	COG1064	alcohol dehydrogenase
BC2225	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC2232	COG0517	IMP dehydrogenase activity
BC2232	COG1125	glycine betaine transport
BC2233	COG1174	glycine betaine transport
BC2240	COG1253	flavin adenine dinucleotide binding
BC2241	COG1012	belongs to the aldehyde dehydrogenase family
BC2242	COG5506	Protein of unknown function (DUF1694)
BC2245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC2246	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BC2247	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BC2248	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC2249	COG0456	acetyltransferase
BC2250	COG3829	transcription factor binding
BC2251	COG1509	lysine 2,3-aminomutase activity
BC2258	COG4991	sh3 domain protein
BC2258	COG0515	serine threonine protein kinase
BC2258	COG3064	Membrane
BC2260	COG0671	phosphoesterase, PA-phosphatase related
BC2261	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC2262	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC2278	COG0300	oxidoreductase activity
BC2281	COG4499	WXG100 protein secretion system (Wss), protein YukC
BC2281	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC2283	COG2814	Major facilitator Superfamily
BC2284	COG4841	protein insertion into membrane
BC2285	COG0372	Belongs to the citrate synthase family
BC2286	COG2079	MmgE PrpD family protein
BC2287	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BC2288	COG1960	acyl-CoA dehydrogenase activity
BC2289	COG2084	Dehydrogenase
BC2291	COG1280	lysine exporter protein (LysE YggA)
BC2292	COG1024	Enoyl-CoA hydratase
BC2295	COG0420	3'-5' exonuclease activity
BC2296	COG0419	ATPase involved in DNA repair
BC2300	COG2223	nitrite transmembrane transporter activity
BC2302	COG1028	Short-chain dehydrogenase reductase Sdr
BC2303	COG1169	isochorismate synthase
BC2304	COG1021	2,3-dihydroxybenzoate-AMP ligase
BC2305	COG3433	isochorismatase activity
BC2305	COG1535	isochorismatase
BC2308	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC2309	COG3251	PFAM MbtH domain protein
BC2310	COG2814	Major facilitator Superfamily
BC2313	COG0776	regulation of translation
BC2315	COG2318	DinB family
BC2317	COG1115	amino acid carrier protein
BC2321	COG1187	pseudouridine synthase activity
BC2322	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC2323	COG1136	(ABC) transporter
BC2325	COG2814	Major facilitator Superfamily
BC2328	COG0028	Belongs to the TPP enzyme family
BC2335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC2339	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC2342	COG2801	Transposase and inactivated derivatives
BC2343	COG2963	transposase activity
BC2349	COG1247	-acetyltransferase
BC2354	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BC2356	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC2362	COG0583	DNA-binding transcription factor activity
BC2363	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC2367	COG0583	DNA-binding transcription factor activity
BC2368	COG2258	MOSC domain
BC2371	COG1132	(ABC) transporter
BC2372	COG1132	(ABC) transporter
BC2379	COG1396	sequence-specific DNA binding
BC2385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC2386	COG1595	DNA-templated transcription, initiation
BC2392	COG1649	PFAM Uncharacterised BCR, COG1649
BC2397	COG2971	BadF BadG BcrA BcrD
BC2399	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BC2401	COG1846	Transcriptional regulator
BC2406	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC2410	COG1309	transcriptional regulator
BC2421	COG0582	viral genome integration into host DNA
BC2430	COG3615	Tellurite resistance protein tehB
BC2430	COG0500	methyltransferase
BC2432	COG2226	methyltransferase
BC2433	COG3961	Belongs to the TPP enzyme family
BC2434	COG1846	Transcriptional regulator
BC2439	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC2444	COG2002	toxin-antitoxin pair type II binding
BC2446	COG0730	response to heat
BC2447	COG0110	maltose O-acetyltransferase activity
BC2448	COG1686	Belongs to the peptidase S11 family
BC2450	COG2814	Major facilitator Superfamily
BC2451	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BC2460	COG2312	Erythromycin esterase
BC2461	COG0741	lytic transglycosylase activity
BC2462	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC2467	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC2468	COG0768	penicillin binding
BC2469	COG1595	DNA-templated transcription, initiation
BC2471	COG0768	penicillin binding
BC2474	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC2476	COG1408	metallophosphoesterase
BC2478	COG1131	(ABC) transporter
BC2480	COG1309	transcriptional regulator
BC2484	COG0439	Biotin carboxylase
BC2485	COG0511	ligase activity, forming carbon-carbon bonds
BC2486	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BC2487	COG1024	Enoyl-CoA hydratase
BC2488	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BC2489	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC2490	COG2963	transposase activity
BC2491	COG2801	Transposase and inactivated derivatives
BC2496	COG1686	Belongs to the peptidase S11 family
BC2503	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BC2506	COG3227	Zinc metalloprotease (Elastase)
BC2507	COG2207	Transcriptional regulator
BC2513	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC2515	COG2814	Major facilitator Superfamily
BC2516	COG1028	Short-chain dehydrogenase reductase Sdr
BC2517	COG1733	regulation of RNA biosynthetic process
BC2526	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC2529	COG1063	alcohol dehydrogenase
BC2531	COG2323	membrane
BC2532	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BC2534	COG3386	PFAM SMP-30 Gluconolaconase
BC2535	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BC2536	COG3773	Cell wall hydrolase
BC2538	COG0745	RESPONSE REGULATOR receiver
BC2539	COG2205	protein histidine kinase activity
BC2541	COG0488	(ABC) transporter
BC2543	COG1136	(ABC) transporter
BC2544	COG0577	efflux transmembrane transporter activity
BC2548	COG0460	homoserine dehydrogenase
BC2549	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC2551	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BC2556	COG0582	viral genome integration into host DNA
BC2575	COG0582	viral genome integration into host DNA
BC2599	COG4824	toxin secretion phage lysis holin
BC2609	COG2124	cytochrome p450
BC2613	COG2124	cytochrome p450
BC2618	COG0561	phosphatase activity
BC2619	COG5002	protein histidine kinase activity
BC2620	COG0768	penicillin binding
BC2622	COG1819	glycosyl
BC2623	COG1794	racemase activity, acting on amino acids and derivatives
BC2629	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BC2632	COG3708	Transcriptional regulator
BC2632	COG2207	Transcriptional regulator
BC2640	COG1335	isochorismatase
BC2643	COG0546	phosphoglycolate phosphatase activity
BC2645	COG0519	Catalyzes the synthesis of GMP from XMP
BC2646	COG3344	reverse transcriptase
BC2659	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC2660	COG0604	alcohol dehydrogenase
BC2661	COG0671	phosphoesterase, PA-phosphatase related
BC2662	COG0768	penicillin binding
BC2671	COG0693	protein deglycase activity
BC2673	COG2814	Major facilitator Superfamily
BC2676	COG0584	glycerophosphoryl diester phosphodiesterase
BC2680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC2681	COG0697	spore germination
BC2688	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC2689	COG2223	nitrite transmembrane transporter activity
BC2693	COG0592	DNA-directed DNA polymerase activity
BC2697	COG0251	oxidation-reduction process
BC2698	COG3878	Protein conserved in bacteria
BC2704	COG4667	esterase of the alpha-beta hydrolase superfamily
BC2713	COG0322	excinuclease ABC activity
BC2719	COG1131	(ABC) transporter
BC2723	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC2730	COG1011	Hydrolase
BC2733	COG1073	alpha beta
BC2734	COG1523	belongs to the glycosyl hydrolase 13 family
BC2735	COG3227	Zinc metalloprotease (Elastase)
BC2740	COG0201	protein transport
BC2741	COG0697	spore germination
BC2742	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC2743	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC2749	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC2752	COG2959	enzyme of heme biosynthesis
BC2760	COG1309	transcriptional regulator
BC2766	COG3284	Transcriptional regulator
BC2770	COG1349	DNA-binding transcription factor activity
BC2773	COG1959	2 iron, 2 sulfur cluster binding
BC2776	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC2777	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC2778	COG0022	dehydrogenase e1 component
BC2779	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC2781	COG1028	Short-chain dehydrogenase reductase Sdr
BC2782	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC2782	COG0456	acetyltransferase
BC2790	COG4176	ABC-type proline glycine betaine transport system permease component
BC2791	COG4175	Glycine betaine
BC2791	COG0517	IMP dehydrogenase activity
BC2797	COG2153	protein acetylation
BC2798	COG3397	chitin binding
BC2799	COG1819	glycosyl
BC2802	COG2205	protein histidine kinase activity
BC2803	COG2226	methyltransferase
BC2804	COG2315	Protein conserved in bacteria
BC2815	COG0514	ATP-dependent DNA helicase (RecQ)
BC2821	COG2801	Transposase and inactivated derivatives
BC2824	COG4637	Psort location Cytoplasmic, score
BC2827	COG3397	chitin binding
BC2830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BC2831	COG1115	amino acid carrier protein
BC2832	COG1012	belongs to the aldehyde dehydrogenase family
BC2833	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BC2835	COG3938	Belongs to the proline racemase family
BC2836	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BC2846	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BC2848	COG4166	transmembrane transport
BC2850	COG4948	Mandelate Racemase Muconate Lactonizing
BC2853	COG0667	Aldo Keto reductase
BC2863	COG3850	Histidine kinase
BC2863	COG5002	protein histidine kinase activity
BC2864	COG0745	RESPONSE REGULATOR receiver
BC2870	COG1164	Oligoendopeptidase f
BC2871	COG1307	EDD domain protein, DegV family
BC2880	COG2814	Major facilitator Superfamily
BC2882	COG1664	Polymer-forming cytoskeletal
BC2883	COG0789	Transcriptional regulator
BC2884	COG4533	DNA binding
BC2885	COG2814	Major facilitator Superfamily
BC2885	COG0477	Major facilitator Superfamily
BC2888	COG2261	transglycosylase associated protein
BC2891	COG2226	methyltransferase
BC2896	COG0436	Aminotransferase
BC2897	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BC2902	COG1131	(ABC) transporter
BC2907	COG0628	permease
BC2909	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC2910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC2911	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC2919	COG2746	aminoglycoside 3-N-acetyltransferase activity
BC2921	COG0697	spore germination
BC2922	COG2318	DinB family
BC2926	COG4912	Dna alkylation repair
BC2927	COG0346	lactoylglutathione lyase activity
BC2928	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC2931	COG0861	Integral membrane protein TerC family
BC2932	COG1368	sulfuric ester hydrolase activity
BC2933	COG0488	(ABC) transporter
BC2936	COG1309	transcriptional regulator
BC2939	COG0287	Prephenate dehydrogenase
BC2942	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC2942	COG1605	Chorismate mutase
BC2952	COG3584	3D domain protein
BC2952	COG1388	LysM domain
BC2954	COG0346	lactoylglutathione lyase activity
BC2960	COG1879	ABC-type sugar transport system periplasmic component
BC2961	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC2962	COG1172	Belongs to the binding-protein-dependent transport system permease family
BC2964	COG2390	Transcriptional regulator
BC2965	COG1070	Carbohydrate kinase
BC2969	COG2329	Antibiotic biosynthesis monooxygenase
BC2973	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC2977	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC2978	COG4187	Peptidase family M20/M25/M40
BC2979	COG1414	Transcriptional regulator
BC2980	COG0833	amino acid
BC2983	COG3239	Fatty acid desaturase
BC2985	COG2720	vancomycin resistance protein
BC2986	COG1785	Belongs to the alkaline phosphatase family
BC2988	COG3655	Transcriptional regulator
BC2992	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC2993	COG0346	lactoylglutathione lyase activity
BC2997	COG0714	Associated with various cellular activities
BC3001	COG0463	Glycosyl transferase, family 2
BC3007	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BC3008	COG0753	catalase activity
BC3018	COG0714	Associated with various cellular activities
BC3024	COG0778	Nitroreductase
BC3025	COG1846	Transcriptional regulator
BC3034	COG0037	tRNA processing
BC3034	COG0590	tRNA wobble adenosine to inosine editing
BC3035	COG0456	acetyltransferase
BC3039	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC3042	COG0642	Histidine kinase
BC3043	COG0745	RESPONSE REGULATOR receiver
BC3044	COG0596	Alpha beta hydrolase
BC3050	COG0730	response to heat
BC3052	COG0833	amino acid
BC3054	COG4335	DNA alkylation repair
BC3061	COG0768	penicillin binding
BC3067	COG1984	allophanate hydrolase subunit 2
BC3068	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BC3069	COG1414	Transcriptional regulator
BC3071	COG3142	Participates in the control of copper homeostasis
BC3072	COG0640	Transcriptional regulator
BC3077	COG3314	Sporulation integral membrane protein YlbJ
BC3081	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BC3087	COG0574	Belongs to the PEP-utilizing enzyme family
BC3087	COG3848	Pyruvate phosphate dikinase
BC3088	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC3092	COG1063	alcohol dehydrogenase
BC3093	COG1027	Aspartate ammonia-lyase
BC3094	COG0252	asparaginase activity
BC3095	COG1396	sequence-specific DNA binding
BC3100	COG5002	protein histidine kinase activity
BC3105	COG2207	Transcriptional regulator
BC3107	COG0322	excinuclease ABC activity
BC3108	COG0531	amino acid
BC3109	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC3111	COG0531	amino acid
BC3113	COG0784	Response regulator, receiver
BC3114	COG4191	Histidine kinase
BC3116	COG1115	amino acid carrier protein
BC3118	COG2124	cytochrome p450
BC3121	COG0737	Belongs to the 5'-nucleotidase family
BC3122	COG2267	carboxylic ester hydrolase activity
BC3123	COG1335	isochorismatase
BC3127	COG0583	DNA-binding transcription factor activity
BC3128	COG1846	Transcriptional regulator
BC3129	COG0598	Magnesium transport protein CorA
BC3133	COG1073	alpha beta
BC3137	COG0415	Belongs to the DNA photolyase family
BC3140	COG0288	reversible hydration of carbon dioxide
BC3142	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC3143	COG5609	conserved protein (DUF2294)
BC3144	COG5609	conserved protein (DUF2294)
BC3148	COG0456	acetyltransferase
BC3149	COG1575	Belongs to the MenA family. Type 1 subfamily
BC3151	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC3153	COG0798	PFAM Bile acid sodium symporter
BC3154	COG0346	lactoylglutathione lyase activity
BC3155	COG0640	Transcriptional regulator
BC3158	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BC3159	COG3320	Male sterility
BC3159	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC3160	COG1309	transcriptional regulator
BC3162	COG2814	Major facilitator Superfamily
BC3163	COG1309	transcriptional regulator
BC3164	COG2068	MobA-Related Protein
BC3165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BC3174	COG1028	Short-chain dehydrogenase reductase Sdr
BC3175	COG1522	sequence-specific DNA binding
BC3178	COG0346	lactoylglutathione lyase activity
BC3189	COG0814	amino acid
BC3190	COG0583	DNA-binding transcription factor activity
BC3191	COG0697	spore germination
BC3200	COG0745	RESPONSE REGULATOR receiver
BC3201	COG5002	protein histidine kinase activity
BC3201	COG3850	Histidine kinase
BC3212	COG2814	Major facilitator Superfamily
BC3216	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BC3219	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BC3223	COG0577	efflux transmembrane transporter activity
BC3227	COG5002	protein histidine kinase activity
BC3227	COG3850	Histidine kinase
BC3229	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC3231	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC3233	COG0738	Major facilitator superfamily
BC3235	COG0738	Major facilitator superfamily
BC3241	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BC3243	COG1335	isochorismatase
BC3244	COG1522	sequence-specific DNA binding
BC3245	COG0531	amino acid
BC3248	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BC3252	COG0662	Cupin 2, conserved barrel domain protein
BC3253	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC3253	COG2207	Transcriptional regulator
BC3257	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC3257	COG3409	Peptidoglycan-binding domain 1 protein
BC3294	COG5444	nuclease activity
BC3307	COG1876	peptidase activity
BC3308	COG2843	Capsule synthesis protein
BC3310	COG0477	Major facilitator Superfamily
BC3313	COG1846	Transcriptional regulator
BC3314	COG2814	Major facilitator Superfamily
BC3316	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BC3320	COG1733	regulation of RNA biosynthetic process
BC3321	COG0778	Nitroreductase
BC3327	COG1028	Short-chain dehydrogenase reductase Sdr
BC3329	COG1131	(ABC) transporter
BC3334	COG1011	Hydrolase
BC3335	COG2365	Tyrosine phosphatase family
BC3342	COG0628	permease
BC3347	COG0500	methyltransferase
BC3349	COG0477	Major facilitator Superfamily
BC3355	COG1253	flavin adenine dinucleotide binding
BC3356	COG0789	Transcriptional regulator
BC3358	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC3364	COG0697	spore germination
BC3366	COG1357	PFAM Pentapeptide repeats (8 copies)
BC3367	COG3813	Protein conserved in bacteria
BC3368	COG2706	6-phosphogluconolactonase activity
BC3369	COG1070	Carbohydrate kinase
BC3372	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BC3377	COG0604	alcohol dehydrogenase
BC3378	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BC3382	COG1028	Short-chain dehydrogenase reductase Sdr
BC3385	COG0840	transmembrane signaling receptor activity
BC3387	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC3387	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC3388	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC3388	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BC3389	COG1733	regulation of RNA biosynthetic process
BC3392	COG0656	L-ascorbic acid biosynthetic process
BC3393	COG2814	Major facilitator Superfamily
BC3398	COG0814	amino acid
BC3404	COG1733	regulation of RNA biosynthetic process
BC3405	COG2188	Transcriptional regulator
BC3406	COG0673	inositol 2-dehydrogenase activity
BC3407	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BC3408	COG1733	regulation of RNA biosynthetic process
BC3409	COG1733	regulation of RNA biosynthetic process
BC3414	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC3418	COG0384	phenazine biosynthesis protein PhzF
BC3419	COG0318	PFAM AMP-dependent synthetase and ligase
BC3420	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC3421	COG1733	regulation of RNA biosynthetic process
BC3426	COG1191	sigma factor activity
BC3428	COG1280	lysine exporter protein (LysE YggA)
BC3439	COG1151	hydroxylamine reductase activity
BC3441	COG3409	Peptidoglycan-binding domain 1 protein
BC3441	COG3757	hydrolase, family 25
BC3447	COG2072	flavoprotein involved in K transport
BC3455	COG1113	amino acid transport
BC3456	COG2814	Major facilitator Superfamily
BC3462	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BC3463	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC3465	COG1247	-acetyltransferase
BC3466	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC3467	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC3468	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC3469	COG3739	integral membrane protein
BC3473	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC3476	COG0583	DNA-binding transcription factor activity
BC3480	COG1193	negative regulation of DNA recombination
BC3483	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BC3484	COG1164	Oligoendopeptidase f
BC3490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BC3495	COG0584	glycerophosphoryl diester phosphodiesterase
BC3497	COG0640	Transcriptional regulator
BC3498	COG0604	alcohol dehydrogenase
BC3501	COG0457	Tetratricopeptide repeat
BC3504	COG0277	FAD linked oxidase domain protein
BC3509	COG1183	phosphatidylcholine synthase activity
BC3511	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC3511	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC3512	COG1252	NADH dehydrogenase
BC3514	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC3516	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BC3518	COG0457	Tetratricopeptide repeat
BC3522	COG1309	transcriptional regulator
BC3528	COG3852	Histidine kinase
BC3530	COG1285	pathogenesis
BC3532	COG2514	catechol 2,3-dioxygenase activity
BC3533	COG2720	vancomycin resistance protein
BC3541	COG0716	FMN binding
BC3543	COG0494	nUDIX hydrolase
BC3548	COG1028	Short-chain dehydrogenase reductase Sdr
BC3550	COG0165	Argininosuccinate lyase
BC3553	COG4145	pantothenate transmembrane transporter activity
BC3555	COG1012	belongs to the aldehyde dehydrogenase family
BC3556	COG1028	Short-chain dehydrogenase reductase Sdr
BC3557	COG1657	PFAM Prenyltransferase squalene oxidase
BC3558	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BC3559	COG2962	Rard protein
BC3560	COG3326	Membrane
BC3563	COG0489	protein tyrosine kinase activity
BC3565	COG0314	molybdopterin synthase activity
BC3566	COG0303	'Molybdopterin
BC3568	COG2116	formate transmembrane transporter activity
BC3570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BC3571	COG5609	conserved protein (DUF2294)
BC3572	COG2427	Protein of unknown function (DUF1641)
BC3573	COG3383	formate dehydrogenase (NAD+) activity
BC3574	COG0697	spore germination
BC3577	COG0531	amino acid
BC3583	COG2226	methyltransferase
BC3584	COG4166	transmembrane transport
BC3585	COG4166	transmembrane transport
BC3586	COG4166	transmembrane transport
BC3587	COG1316	TRANSCRIPTIONal
BC3589	COG1595	DNA-templated transcription, initiation
BC3591	COG1131	(ABC) transporter
BC3595	COG0673	inositol 2-dehydrogenase activity
BC3596	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BC3597	COG0187	DNA topoisomerase II activity
BC3599	COG1832	CoA-binding protein
BC3600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC3601	COG0745	RESPONSE REGULATOR receiver
BC3605	COG4841	protein insertion into membrane
BC3606	COG0824	Thioesterase
BC3612	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC3616	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BC3622	COG2211	Major facilitator Superfamily
BC3627	COG0183	Belongs to the thiolase family
BC3628	COG0318	PFAM AMP-dependent synthetase and ligase
BC3629	COG1268	BioY protein
BC3639	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC3641	COG5002	protein histidine kinase activity
BC3642	COG0400	carboxylic ester hydrolase activity
BC3643	COG0346	lactoylglutathione lyase activity
BC3644	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BC3646	COG0069	glutamate synthase activity
BC3647	COG1902	pentaerythritol trinitrate reductase activity
BC3648	COG1329	Transcriptional regulator
BC3661	COG4846	Membrane protein involved in cytochrome C biogenesis
BC3662	COG0785	Cytochrome C biogenesis protein
BC3664	COG1473	amidohydrolase
BC3666	COG1131	(ABC) transporter
BC3668	COG0583	DNA-binding transcription factor activity
BC3670	COG1346	cytolysis
BC3673	COG0730	response to heat
BC3678	COG1132	(ABC) transporter
BC3679	COG1132	(ABC) transporter
BC3684	COG3639	organic phosphonate transmembrane transporter activity
BC3686	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC3687	COG0737	Belongs to the 5'-nucleotidase family
BC3689	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BC3693	COG1695	Transcriptional regulator
BC3694	COG5632	N-Acetylmuramoyl-L-alanine amidase
BC3698	COG1196	nuclear chromosome segregation
BC3698	COG0741	lytic transglycosylase activity
BC3698	COG0739	heme binding
BC3699	COG0741	lytic transglycosylase activity
BC3704	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BC3706	COG0789	Transcriptional regulator
BC3707	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BC3708	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BC3709	COG2860	membrane
BC3718	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC3718	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BC3718	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC3719	COG1105	Belongs to the carbohydrate kinase PfkB family
BC3720	COG1349	DNA-binding transcription factor activity
BC3721	COG1979	alcohol dehydrogenase
BC3722	COG2322	membrane
BC3724	COG1113	amino acid transport
BC3726	COG1408	metallophosphoesterase
BC3727	COG2116	formate transmembrane transporter activity
BC3730	COG2217	Heavy metal translocating P-type atpase
BC3731	COG2608	mercury ion transmembrane transporter activity
BC3732	COG1937	Protein conserved in bacteria
BC3734	COG2819	hydrolase of the alpha beta superfamily
BC3735	COG1120	ATPase activity
BC3736	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC3737	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC3738	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC3739	COG0708	Exodeoxyribonuclease III
BC3740	COG2169	Transcriptional regulator
BC3741	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BC3742	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BC3746	COG2267	carboxylic ester hydrolase activity
BC3747	COG5001	Diguanylate cyclase
BC3747	COG3300	MHYT domain
BC3750	COG1086	Polysaccharide biosynthesis protein
BC3754	COG1346	cytolysis
BC3756	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BC3759	COG2723	6-phospho-beta-galactosidase activity
BC3760	COG2723	6-phospho-beta-galactosidase activity
BC3762	COG1404	Belongs to the peptidase S8 family
BC3765	COG1368	sulfuric ester hydrolase activity
BC3766	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BC3771	COG4550	Control of competence regulator ComK, YlbF/YmcA
BC3773	COG1013	pyruvate-flavodoxin oxidoreductase activity
BC3774	COG0674	pyruvate-flavodoxin oxidoreductase activity
BC3774	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BC3776	COG2359	stage V sporulation protein S
BC3777	COG1692	metallophosphoesterase
BC3781	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BC3782	COG1426	Protein conserved in bacteria
BC3785	COG0300	oxidoreductase activity
BC3786	COG0612	Peptidase, M16
BC3787	COG0612	Peptidase, M16
BC3788	COG1079	Belongs to the binding-protein-dependent transport system permease family
BC3790	COG3845	ABC transporter
BC3791	COG1744	ABC transporter substrate-binding protein PnrA-like
BC3792	COG2188	Transcriptional regulator
BC3795	COG0740	serine-type endopeptidase activity
BC3796	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC3798	COG0527	aspartate kinase activity
BC3799	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BC3800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC3801	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC3802	COG1873	PFAM PRC-barrel domain
BC3803	COG0612	Peptidase, M16
BC3804	COG0726	polysaccharide deacetylase
BC3807	COG0196	riboflavin kinase activity
BC3809	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BC3810	COG1550	Protein conserved in bacteria
BC3812	COG1358	cellular component organization or biogenesis
BC3813	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BC3814	COG0195	Participates in both transcription termination and antitermination
BC3820	COG4589	Belongs to the CDS family
BC3829	COG4974	Belongs to the 'phage' integrase family
BC3831	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BC3832	COG0758	DNA mediated transformation
BC3833	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BC3841	COG1837	Belongs to the UPF0109 family
BC3843	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BC3845	COG0552	protein localization to endoplasmic reticulum
BC3846	COG1196	nuclear chromosome segregation
BC3848	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BC3849	COG1028	Short-chain dehydrogenase reductase Sdr
BC3850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BC3853	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BC3854	COG1461	Dihydroxyacetone kinase
BC3855	COG1302	Protein conserved in bacteria
BC3857	COG1564	THIamine pyrophosphokinase
BC3858	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BC3860	COG0515	serine threonine protein kinase
BC3860	COG2815	serine threonine protein kinase
BC3861	COG0631	protein serine/threonine phosphatase activity
BC3863	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BC3863	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BC3866	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BC3867	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BC3871	COG1561	YicC-like family, N-terminal region
BC3875	COG0006	proline dipeptidase activity
BC3879	COG3069	C4-dicarboxylate transmembrane transporter activity
BC3892	COG0564	pseudouridine synthase activity
BC3896	COG3599	regulation of cell shape
BC3897	COG2302	S4 RNA-binding domain
BC3898	COG0762	integral membrane protein
BC3900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BC3902	COG1873	PFAM PRC-barrel domain
BC3903	COG1191	sigma factor activity
BC3904	COG1191	sigma factor activity
BC3906	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BC3907	COG0849	cell division
BC3911	COG0772	Belongs to the SEDS family
BC3915	COG0768	penicillin binding
BC3916	COG0768	penicillin binding
BC3920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BC3923	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BC3924	COG1399	metal-binding, possibly nucleic acid-binding protein
BC3926	COG3480	Lon protease (S16) C-terminal proteolytic domain
BC3927	COG1752	Esterase of the alpha-beta hydrolase superfamily
BC3928	COG3314	Sporulation integral membrane protein YlbJ
BC3930	COG0742	ribosomal rna small subunit methyltransferase
BC3933	COG3679	Belongs to the UPF0342 family
BC3934	COG0406	alpha-ribazole phosphatase activity
BC3937	COG2340	Cysteine-rich secretory protein family
BC3940	COG3336	cytochrome c oxidase
BC3947	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BC3948	COG0772	Belongs to the SEDS family
BC3950	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BC3951	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BC3953	COG4896	Protein conserved in bacteria
BC3956	COG1217	gtp-binding protein TYPA
BC3958	COG0483	inositol monophosphate 1-phosphatase activity
BC3972	COG0022	dehydrogenase e1 component
BC3973	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC3975	COG0561	phosphatase activity
BC3977	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BC3978	COG0569	domain protein
BC3982	COG0583	DNA-binding transcription factor activity
BC3983	COG0517	IMP dehydrogenase activity
BC3985	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BC3986	COG4703	Protein of unknown function (DUF1797)
BC3989	COG2200	EAL domain
BC3990	COG1028	Short-chain dehydrogenase reductase Sdr
BC3991	COG1408	metallophosphoesterase
BC4000	COG2814	Major facilitator Superfamily
BC4005	COG3209	COG3209 Rhs family protein
BC4007	COG2205	protein histidine kinase activity
BC4009	COG0436	Aminotransferase
BC4010	COG1609	Transcriptional regulator
BC4011	COG3833	ABC-type maltose transport systems, permease component
BC4012	COG1175	transmembrane transport
BC4015	COG0366	Alpha amylase catalytic
BC4016	COG3842	ATPase activity
BC4023	COG0183	Belongs to the thiolase family
BC4029	COG1695	Transcriptional regulator
BC4030	COG1028	Short-chain dehydrogenase reductase Sdr
BC4034	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BC4035	COG0436	Aminotransferase
BC4042	COG2084	Dehydrogenase
BC4044	COG2199	diguanylate cyclase activity
BC4045	COG0778	Nitroreductase
BC4050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BC4050	COG2190	(PTS) system
BC4050	COG1263	PTS System
BC4051	COG3711	transcriptional antiterminator
BC4053	COG2188	Transcriptional regulator
BC4055	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BC4059	COG1547	Domain of unknown function (DUF309)
BC4060	COG0456	acetyltransferase
BC4061	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BC4062	COG4086	secreted protein
BC4063	COG0561	phosphatase activity
BC4064	COG0697	spore germination
BC4067	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC4071	COG0733	neurotransmitter:sodium symporter activity
BC4075	COG1686	Belongs to the peptidase S11 family
BC4076	COG1725	Transcriptional regulator
BC4077	COG1131	(ABC) transporter
BC4081	COG1846	Transcriptional regulator
BC4084	COG0598	Magnesium transport protein CorA
BC4089	COG4974	Belongs to the 'phage' integrase family
BC4091	COG0735	belongs to the Fur family
BC4092	COG1300	Membrane
BC4096	COG0667	Aldo Keto reductase
BC4097	COG0656	L-ascorbic acid biosynthetic process
BC4098	COG0456	acetyltransferase
BC4098	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BC4100	COG0737	Belongs to the 5'-nucleotidase family
BC4100	COG4085	toxin activity
BC4100	COG1525	nuclease
BC4102	COG0596	Alpha beta hydrolase
BC4103	COG2056	Na+-H+ antiporter family
BC4104	COG1609	Transcriptional regulator
BC4105	COG0456	acetyltransferase
BC4106	COG1073	alpha beta
BC4109	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC4109	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BC4110	COG0307	riboflavin synthase, alpha
BC4116	COG2226	methyltransferase
BC4116	COG1073	alpha beta
BC4119	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BC4121	COG1757	Na H antiporter
BC4124	COG1522	sequence-specific DNA binding
BC4133	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC4134	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC4135	COG1760	l-serine dehydratase
BC4136	COG1760	l-serine dehydratase
BC4141	COG1285	pathogenesis
BC4143	COG2195	Cleaves the N-terminal amino acid of tripeptides
BC4144	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC4146	COG1376	ErfK ybiS ycfS ynhG family protein
BC4147	COG4129	membrane
BC4148	COG1126	abc transporter atp-binding protein
BC4149	COG0765	amino acid transport
BC4150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BC4153	COG2816	NAD+ diphosphatase activity
BC4154	COG2323	membrane
BC4155	COG0772	Belongs to the SEDS family
BC4157	COG0508	dehydrogenase complex catalyzes the overall conversion of
BC4158	COG0022	dehydrogenase e1 component
BC4159	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BC4160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BC4163	COG0280	phosphate acetyltransferase
BC4165	COG3290	protein histidine kinase activity
BC4165	COG3829	transcription factor binding
BC4167	COG0584	glycerophosphoryl diester phosphodiesterase
BC4168	COG3093	addiction module antidote protein HigA
BC4172	COG0750	zinc metalloprotease
BC4175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BC4177	COG0142	geranyltranstransferase activity
BC4182	COG1302	Protein conserved in bacteria
BC4183	COG0439	Biotin carboxylase
BC4184	COG0511	ligase activity, forming carbon-carbon bonds
BC4193	COG3854	ATPases associated with a variety of cellular activities
BC4198	COG0006	proline dipeptidase activity
BC4201	COG3872	metal-dependent enzyme
BC4203	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BC4210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC4211	COG1609	Transcriptional regulator
BC4213	COG2076	Multidrug Resistance protein
BC4214	COG2076	Multidrug Resistance protein
BC4221	COG1131	(ABC) transporter
BC4222	COG1725	Transcriptional regulator
BC4227	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC4238	COG1459	type II secretion system
BC4239	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BC4250	COG0646	methionine synthase
BC4250	COG1410	methionine synthase
BC4251	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BC4251	COG0646	methionine synthase
BC4253	COG0626	cystathionine gamma-synthase activity
BC4254	COG0626	cystathionine gamma-synthase activity
BC4258	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC4260	COG1940	carbohydrate kinase activity
BC4261	COG4483	Protein conserved in bacteria
BC4262	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BC4263	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BC4264	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BC4265	COG0704	Plays a role in the regulation of phosphate uptake
BC4267	COG0573	inorganic phosphate transmembrane transporter activity
BC4268	COG0573	inorganic phosphate transmembrane transporter activity
BC4269	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BC4270	COG0768	penicillin binding
BC4271	COG0477	Major facilitator Superfamily
BC4274	COG5521	maltodextrose utilization protein MalA
BC4277	COG0735	belongs to the Fur family
BC4278	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BC4279	COG1121	(ABC) transporter
BC4280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC4286	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BC4287	COG2384	SAM-dependent methyltransferase
BC4289	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BC4290	COG0358	DNA primase activity
BC4294	COG0517	IMP dehydrogenase activity
BC4297	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BC4298	COG0295	cytidine deaminase activity
BC4299	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BC4301	COG1480	7TM receptor with intracellular HD hydrolase
BC4302	COG1702	phosphate starvation-inducible protein PhoH
BC4306	COG1610	YqeY-like protein
BC4307	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BC4308	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BC4309	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BC4315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BC4316	COG1733	regulation of RNA biosynthetic process
BC4321	COG1466	dna polymerase III delta subunit
BC4322	COG2333	competence protein COMEC
BC4322	COG0658	competence protein
BC4323	COG2131	deaminase
BC4324	COG1596	polysaccharide export
BC4324	COG1555	photosystem II stabilization
BC4325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BC4326	COG2226	methyltransferase
BC4327	COG0799	negative regulation of ribosome biogenesis
BC4328	COG1713	HD superfamily hydrolase involved in NAD metabolism
BC4332	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BC4333	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BC4340	COG0778	Nitroreductase
BC4341	COG2357	RelA SpoT domain protein
BC4343	COG1785	Belongs to the alkaline phosphatase family
BC4345	COG2267	carboxylic ester hydrolase activity
BC4351	COG1404	Belongs to the peptidase S8 family
BC4352	COG3186	Phenylalanine-4-hydroxylase
BC4354	COG2514	catechol 2,3-dioxygenase activity
BC4355	COG2259	Doxx family
BC4363	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BC4365	COG1012	belongs to the aldehyde dehydrogenase family
BC4365	COG1454	alcohol dehydrogenase
BC4366	COG0626	cystathionine gamma-synthase activity
BC4367	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BC4372	COG0768	penicillin binding
BC4376	COG0826	peptidase U32
BC4377	COG0826	peptidase U32
BC4378	COG4122	O-methyltransferase activity
BC4379	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BC4385	COG0628	permease
BC4389	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BC4392	COG1104	cysteine desulfurase activity
BC4393	COG1959	2 iron, 2 sulfur cluster binding
BC4394	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BC4396	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BC4401	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BC4403	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BC4403	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BC4404	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BC4405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC4405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BC4407	COG2244	polysaccharide biosynthetic process
BC4408	COG2323	membrane
BC4410	COG1862	Preprotein translocase
BC4416	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BC4422	COG0157	Belongs to the NadC ModD family
BC4423	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BC4424	COG1104	cysteine desulfurase activity
BC4425	COG1827	regulation of RNA biosynthetic process
BC4426	COG2258	MOSC domain
BC4427	COG0077	Prephenate dehydratase
BC4430	COG0577	efflux transmembrane transporter activity
BC4431	COG1136	(ABC) transporter
BC4432	COG5002	protein histidine kinase activity
BC4433	COG0745	RESPONSE REGULATOR receiver
BC4435	COG3290	protein histidine kinase activity
BC4437	COG2868	ribosomal protein
BC4439	COG1530	ribonuclease E activity
BC4440	COG1994	Peptidase M50
BC4441	COG0739	heme binding
BC4442	COG2894	cell division
BC4446	COG1077	Cell shape determining protein MreB Mrl
BC4456	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC4457	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BC4464	COG0285	dihydrofolate synthase activity
BC4467	COG1388	LysM domain
BC4469	COG0113	porphobilinogen synthase activity
BC4470	COG1587	Uroporphyrinogen-III synthase
BC4472	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BC4474	COG1846	Transcriptional regulator
BC4475	COG1764	response to oxidative stress
BC4478	COG1067	ATP-dependent peptidase activity
BC4478	COG0470	DNA polymerase III
BC4487	COG0210	DNA helicase
BC4492	COG0622	Phosphoesterase
BC4495	COG5401	PFAM Sporulation and spore germination
BC4499	COG1309	transcriptional regulator
BC4501	COG2197	response regulator
BC4502	COG2233	PERMEase
BC4503	COG0402	S-adenosylhomocysteine deaminase activity
BC4504	COG1983	PspC domain protein
BC4505	COG1396	sequence-specific DNA binding
BC4508	COG1959	2 iron, 2 sulfur cluster binding
BC4509	COG1668	transmembrane transport
BC4510	COG4152	abc transporter atp-binding protein
BC4511	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BC4512	COG1360	Flagellar Motor Protein
BC4513	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BC4514	COG1876	peptidase activity
BC4515	COG0824	Thioesterase
BC4516	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BC4517	COG1053	succinate dehydrogenase
BC4518	COG2009	succinate dehydrogenase
BC4519	COG1719	4-vinyl reductase, 4VR
BC4521	COG3118	belongs to the thioredoxin family
BC4523	COG2086	electron transfer activity
BC4524	COG1024	Enoyl-CoA hydratase
BC4525	COG1309	transcriptional regulator
BC4526	COG0318	PFAM AMP-dependent synthetase and ligase
BC4531	COG2318	DinB family
BC4537	COG1131	(ABC) transporter
BC4538	COG2205	protein histidine kinase activity
BC4539	COG0745	RESPONSE REGULATOR receiver
BC4540	COG4895	conserved protein (DUF2196)
BC4541	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BC4543	COG4509	Sortase family
BC4544	COG1120	ATPase activity
BC4547	COG5386	Cell surface protein
BC4549	COG5386	Cell surface protein
BC4550	COG1114	Component of the transport system for branched-chain amino acids
BC4551	COG1187	pseudouridine synthase activity
BC4553	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BC4553	COG1796	DNA polymerase
BC4554	COG1286	toxin biosynthetic process
BC4562	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BC4564	COG1418	mRNA catabolic process
BC4568	COG2814	Major facilitator Superfamily
BC4569	COG1566	PFAM secretion protein HlyD family protein
BC4570	COG1309	transcriptional regulator
BC4571	COG1363	Peptidase, m42
BC4576	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BC4579	COG1484	DNA-dependent DNA replication
BC4580	COG3611	Membrane attachment protein
BC4582	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BC4583	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC4585	COG1971	Probably functions as a manganese efflux pump
BC4587	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC4587	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BC4588	COG5002	protein histidine kinase activity
BC4589	COG0745	RESPONSE REGULATOR receiver
BC4593	COG0538	isocitrate dehydrogenase activity
BC4594	COG0372	Belongs to the citrate synthase family
BC4597	COG0628	permease
BC4598	COG3030	protein affecting phage T7 exclusion by the F plasmid
BC4603	COG1725	Transcriptional regulator
BC4604	COG0281	malic enzyme
BC4605	COG0587	DNA-directed DNA polymerase activity
BC4608	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BC4611	COG4109	DRTGG domain
BC4614	COG0006	proline dipeptidase activity
BC4620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC4621	COG0662	Cupin 2, conserved barrel domain protein
BC4624	COG1028	Short-chain dehydrogenase reductase Sdr
BC4625	COG0589	response to stress
BC4633	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC4638	COG0827	DNA restriction-modification system
BC4639	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BC4640	COG3874	Sporulation protein YtfJ
BC4643	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BC4645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC4648	COG1104	cysteine desulfurase activity
BC4650	COG0583	DNA-binding transcription factor activity
BC4651	COG0697	spore germination
BC4652	COG1309	transcriptional regulator
BC4653	COG1956	GAF domain-containing protein
BC4654	COG0626	cystathionine gamma-synthase activity
BC4658	COG0110	maltose O-acetyltransferase activity
BC4659	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BC4660	COG0454	-acetyltransferase
BC4661	COG0517	IMP dehydrogenase activity
BC4662	COG0123	including yeast histone deacetylase and acetoin utilization protein
BC4665	COG0745	RESPONSE REGULATOR receiver
BC4667	COG0666	response to abiotic stimulus
BC4672	COG1609	Transcriptional regulator
BC4674	COG1605	Chorismate mutase
BC4674	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BC4675	COG4851	CamS sex pheromone cAM373 precursor
BC4676	COG3118	belongs to the thioredoxin family
BC4678	COG2309	aminopeptidase activity
BC4683	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC4686	COG1674	ftsk spoiiie
BC4687	COG1388	LysM domain
BC4687	COG0860	N-Acetylmuramoyl-L-alanine amidase
BC4689	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BC4691	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC4692	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BC4693	COG1363	Peptidase, m42
BC4695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC4698	COG0510	thiamine kinase activity
BC4702	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BC4703	COG1349	DNA-binding transcription factor activity
BC4704	COG1187	pseudouridine synthase activity
BC4705	COG2244	polysaccharide biosynthetic process
BC4706	COG2081	HI0933 family
BC4707	COG2814	Major facilitator Superfamily
BC4709	COG3832	glyoxalase III activity
BC4714	COG1329	Transcriptional regulator
BC4719	COG0314	molybdopterin synthase activity
BC4720	COG1763	Mo-molybdopterin cofactor biosynthetic process
BC4721	COG0303	'Molybdopterin
BC4723	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BC4724	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BC4728	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BC4730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BC4738	COG2814	Major facilitator Superfamily
BC4739	COG0475	glutathione-regulated potassium exporter activity
BC4740	COG0490	domain, Protein
BC4741	COG0582	viral genome integration into host DNA
BC4743	COG1136	(ABC) transporter
BC4746	COG1242	4 iron, 4 sulfur cluster binding
BC4747	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BC4750	COG1794	racemase activity, acting on amino acids and derivatives
BC4753	COG2267	carboxylic ester hydrolase activity
BC4754	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BC4755	COG0671	phosphoesterase, PA-phosphatase related
BC4756	COG0438	transferase activity, transferring glycosyl groups
BC4760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC4770	COG5002	protein histidine kinase activity
BC4771	COG3852	Histidine kinase
BC4774	COG2267	carboxylic ester hydrolase activity
BC4775	COG1368	sulfuric ester hydrolase activity
BC4778	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BC4779	COG1116	anion transmembrane transporter activity
BC4780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BC4785	COG0494	nUDIX hydrolase
BC4789	COG1854	S-ribosylhomocysteine lyase activity
BC4791	COG0288	reversible hydration of carbon dioxide
BC4792	COG1271	oxidase subunit
BC4793	COG1294	oxidase, subunit
BC4796	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC4801	COG1842	Phage shock protein A
BC4803	COG2801	Transposase and inactivated derivatives
BC4809	COG5002	protein histidine kinase activity
BC4810	COG0745	RESPONSE REGULATOR receiver
BC4815	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BC4816	COG1597	lipid kinase activity
BC4823	COG0577	efflux transmembrane transporter activity
BC4828	COG0586	Pfam SNARE associated Golgi protein
BC4829	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BC4830	COG0577	efflux transmembrane transporter activity
BC4831	COG1136	(ABC) transporter
BC4832	COG3708	Transcriptional regulator
BC4832	COG2207	Transcriptional regulator
BC4833	COG5658	integral membrane protein
BC4834	COG0640	Transcriptional regulator
BC4835	COG0745	RESPONSE REGULATOR receiver
BC4836	COG2205	protein histidine kinase activity
BC4837	COG0577	efflux transmembrane transporter activity
BC4838	COG0577	efflux transmembrane transporter activity
BC4839	COG1136	(ABC) transporter
BC4840	COG0577	efflux transmembrane transporter activity
BC4842	COG2188	Transcriptional regulator
BC4846	COG3964	amidohydrolase
BC4853	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BC4854	COG0596	Alpha beta hydrolase
BC4856	COG1169	isochorismate synthase
BC4857	COG1575	Belongs to the MenA family. Type 1 subfamily
BC4858	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BC4863	COG0058	SHG alpha-glucan phosphorylase activity
BC4869	COG1404	Belongs to the peptidase S8 family
BC4889	COG0544	peptidyl-prolyl cis-trans isomerase activity
BC4895	COG1285	pathogenesis
BC4899	COG2155	Conserved Protein
BC4900	COG1098	S1 RNA binding domain
BC4901	COG0436	Aminotransferase
BC4902	COG1522	sequence-specific DNA binding
BC4903	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BC4904	COG2267	carboxylic ester hydrolase activity
BC4906	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BC4910	COG5018	Exonuclease
BC4911	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC4915	COG2050	protein possibly involved in aromatic compounds catabolism
BC4917	COG1268	BioY protein
BC4918	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC4919	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BC4922	COG3584	3D domain protein
BC4925	COG1252	NADH dehydrogenase
BC4928	COG3708	Transcriptional regulator
BC4931	COG1683	Conserved Protein
BC4933	COG4122	O-methyltransferase activity
BC4935	COG0316	Belongs to the HesB IscA family
BC4938	COG1252	NADH dehydrogenase
BC4941	COG0390	transport system, permease component
BC4942	COG2824	Alkylphosphonate utilization operon protein PhnA
BC4951	COG4837	Protein of unknown function (DUF1462)
BC4952	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BC4954	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BC4955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BC4958	COG2249	NAD(P)H dehydrogenase (quinone) activity
BC4959	COG0647	UMP catabolic process
BC4961	COG2445	Protein of unknown function DUF86
BC4962	COG1494	fructose-1,6-bisphosphatase
BC4966	COG4470	Protein conserved in bacteria
BC4968	COG0789	Transcriptional regulator
BC4969	COG4377	Putative membrane peptidase family (DUF2324)
BC4974	COG0739	heme binding
BC4976	COG3377	Domain of unknown function (DUF1805)
BC4977	COG0737	Belongs to the 5'-nucleotidase family
BC4979	COG0719	Fe-S assembly protein
BC4980	COG0822	iron-sulfur transferase activity
BC4981	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BC4982	COG0719	Fe-S assembly protein
BC4983	COG0396	ATPase activity
BC4984	COG1464	Belongs to the NlpA lipoprotein family
BC4985	COG1464	Belongs to the NlpA lipoprotein family
BC4986	COG2011	ABC-type metal ion transport system permease component
BC4989	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BC4990	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BC4992	COG1393	Belongs to the ArsC family
BC5000	COG1309	transcriptional regulator
BC5001	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BC5002	COG1960	acyl-CoA dehydrogenase activity
BC5003	COG0183	Belongs to the thiolase family
BC5004	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC5004	COG1024	Enoyl-CoA hydratase
BC5005	COG1686	Belongs to the peptidase S11 family
BC5008	COG0011	TIGRFAM Protein of
BC5009	COG0840	transmembrane signaling receptor activity
BC5012	COG2814	Major facilitator Superfamily
BC5013	COG0531	amino acid
BC5018	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BC5025	COG0586	Pfam SNARE associated Golgi protein
BC5027	COG1376	ErfK ybiS ycfS ynhG family protein
BC5028	COG0745	RESPONSE REGULATOR receiver
BC5029	COG5002	protein histidine kinase activity
BC5034	COG0840	transmembrane signaling receptor activity
BC5035	COG2151	metal-sulfur cluster biosynthetic enzyme
BC5036	COG3227	Zinc metalloprotease (Elastase)
BC5037	COG1741	Belongs to the pirin family
BC5040	COG0586	Pfam SNARE associated Golgi protein
BC5041	COG0475	glutathione-regulated potassium exporter activity
BC5042	COG0490	domain, Protein
BC5043	COG1115	amino acid carrier protein
BC5044	COG0783	Belongs to the Dps family
BC5046	COG1611	Belongs to the LOG family
BC5048	COG1528	Iron-storage protein
BC5050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC5051	COG1115	amino acid carrier protein
BC5054	COG2910	NAD(P)H-binding
BC5057	COG0656	L-ascorbic acid biosynthetic process
BC5058	COG2814	Major facilitator Superfamily
BC5059	COG1733	regulation of RNA biosynthetic process
BC5061	COG1252	NADH dehydrogenase
BC5065	COG3290	protein histidine kinase activity
BC5065	COG0840	transmembrane signaling receptor activity
BC5072	COG0488	(ABC) transporter
BC5073	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BC5076	COG4221	oxidoreductase activity
BC5079	COG1028	Short-chain dehydrogenase reductase Sdr
BC5097	COG1522	sequence-specific DNA binding
BC5129	COG0557	exoribonuclease II activity
BC5130	COG1647	Serine aminopeptidase, S33
BC5131	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BC5132	COG1346	cytolysis
BC5140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BC5143	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BC5148	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BC5151	COG2323	membrane
BC5153	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BC5155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BC5157	COG1051	belongs to the nudix hydrolase family
BC5159	COG0492	ferredoxin-NADP+ reductase activity
BC5160	COG0457	Tetratricopeptide repeat
BC5161	COG0110	maltose O-acetyltransferase activity
BC5165	COG1950	PFAM Membrane protein of
BC5167	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BC5171	COG0789	Transcriptional regulator
BC5175	COG0583	DNA-binding transcription factor activity
BC5177	COG0655	NAD(P)H dehydrogenase (quinone) activity
BC5178	COG0488	(ABC) transporter
BC5179	COG2963	transposase activity
BC5180	COG2801	Transposase and inactivated derivatives
BC5182	COG1132	(ABC) transporter
BC5183	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC5184	COG0793	Belongs to the peptidase S41A family
BC5184	COG3409	Peptidoglycan-binding domain 1 protein
BC5185	COG2177	Part of the ABC transporter FtsEX involved in
BC5186	COG2884	Cell division ATP-binding protein ftsE
BC5188	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BC5190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BC5191	COG1278	Cold shock
BC5192	COG1040	competence protein
BC5193	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BC5196	COG0791	NLP P60 protein
BC5196	COG1388	LysM domain
BC5197	COG1733	regulation of RNA biosynthetic process
BC5198	COG1307	EDD domain protein, DegV family
BC5199	COG1739	Uncharacterized protein family UPF0029
BC5200	COG1316	TRANSCRIPTIONal
BC5201	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BC5202	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BC5203	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BC5205	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BC5205	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BC5209	COG1486	melibiose metabolic process
BC5210	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC5211	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC5215	COG1447	Phosphotransferase system cellobiose-specific component IIA
BC5217	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BC5218	COG1301	dicarboxylic acid transport
BC5221	COG1511	domain protein
BC5222	COG0583	DNA-binding transcription factor activity
BC5223	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BC5224	COG1271	oxidase subunit
BC5225	COG1294	oxidase, subunit
BC5226	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BC5228	COG1620	l-lactate permease
BC5230	COG2389	metal-binding protein
BC5232	COG1368	sulfuric ester hydrolase activity
BC5234	COG0791	NLP P60 protein
BC5234	COG1388	LysM domain
BC5235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BC5237	COG1215	transferase activity, transferring glycosyl groups
BC5238	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC5239	COG3584	3D domain protein
BC5239	COG1388	LysM domain
BC5244	COG4715	Zinc finger, swim domain protein
BC5245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BC5253	COG0577	efflux transmembrane transporter activity
BC5254	COG1136	(ABC) transporter
BC5261	COG5002	protein histidine kinase activity
BC5262	COG0745	RESPONSE REGULATOR receiver
BC5263	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC5267	COG1216	Glycosyl transferase, family 2
BC5267	COG1442	glycosyl transferase family 8
BC5270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BC5272	COG1181	Belongs to the D-alanine--D-alanine ligase family
BC5273	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BC5274	COG1086	Polysaccharide biosynthesis protein
BC5275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BC5276	COG4464	protein tyrosine phosphatase activity
BC5277	COG0489	protein tyrosine kinase activity
BC5278	COG3944	biosynthesis protein
BC5279	COG0489	protein tyrosine kinase activity
BC5282	COG1609	Transcriptional regulator
BC5283	COG0739	heme binding
BC5286	COG3279	Response regulator of the LytR AlgR family
BC5287	COG2385	sporulation resulting in formation of a cellular spore
BC5290	COG4836	Membrane
BC5291	COG1007	ATP synthesis coupled electron transport
BC5292	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC5293	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BC5295	COG0839	Belongs to the complex I subunit 6 family
BC5299	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BC5302	COG3300	MHYT domain
BC5302	COG5001	Diguanylate cyclase
BC5312	COG0356	it plays a direct role in the translocation of protons across the membrane
BC5318	COG0698	ribose 5-phosphate isomerase
BC5321	COG2259	Doxx family
BC5322	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BC5325	COG0009	L-threonylcarbamoyladenylate synthase
BC5332	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BC5333	COG1494	fructose-1,6-bisphosphatase
BC5337	COG4821	SIS domain
BC5341	COG1960	acyl-CoA dehydrogenase activity
BC5342	COG1960	acyl-CoA dehydrogenase activity
BC5343	COG1250	3-hydroxyacyl-CoA dehydrogenase
BC5344	COG0183	Belongs to the thiolase family
BC5345	COG2181	nitrate reductase activity
BC5345	COG0247	lactate metabolic process
BC5346	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BC5351	COG3227	Zinc metalloprotease (Elastase)
BC5352	COG2197	response regulator
BC5353	COG4585	Histidine kinase
BC5354	COG0842	Transport permease protein
BC5355	COG1131	(ABC) transporter
BC5356	COG0024	Methionine aminopeptidase
BC5359	COG2234	aminopeptidase activity
BC5363	COG1595	DNA-templated transcription, initiation
BC5365	COG4506	Protein conserved in bacteria
BC5366	COG1619	proteins homologs of microcin C7 resistance protein MccF
BC5372	COG2814	Major facilitator Superfamily
BC5373	COG0789	Transcriptional regulator
BC5374	COG0584	glycerophosphoryl diester phosphodiesterase
BC5375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BC5377	COG1994	Peptidase M50
BC5379	COG1078	dGTPase activity
BC5380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BC5381	COG1120	ATPase activity
BC5382	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC5383	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BC5387	COG0280	phosphate acetyltransferase
BC5390	COG3773	Cell wall hydrolase
BC5392	COG2363	Small membrane protein
BC5394	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BC5396	COG0561	phosphatase activity
BC5397	COG2814	Major facilitator Superfamily
BC5399	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BC5400	COG1131	(ABC) transporter
BC5401	COG2755	lipolytic protein G-D-S-L family
BC5402	COG1609	Transcriptional regulator
BC5404	COG0460	homoserine dehydrogenase
BC5406	COG2873	o-acetylhomoserine
BC5408	COG1011	Hydrolase
BC5409	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BC5411	COG2197	response regulator
BC5412	COG2203	Gaf domain
BC5412	COG4585	Histidine kinase
BC5413	COG0351	phosphomethylpyrimidine kinase
BC5414	COG3706	GGDEF domain
BC5415	COG2879	small protein
BC5416	COG1966	Carbon starvation protein
BC5417	COG3279	Response regulator of the LytR AlgR family
BC5418	COG0477	Major facilitator Superfamily
BC5420	COG0438	transferase activity, transferring glycosyl groups
BC5424	COG0840	transmembrane signaling receptor activity
BC5426	COG1607	acyl-coa hydrolase
BC5427	COG1216	Glycosyl transferase, family 2
BC5429	COG1216	Glycosyl transferase, family 2
BC5432	COG0463	Glycosyl transferase, family 2
BC5433	COG0488	(ABC) transporter
BC5434	COG1309	transcriptional regulator
BC5435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BC5436	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC5436	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BC5437	COG0628	permease
BC5442	COG2814	Major facilitator Superfamily
BC5443	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BC5444	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BC5448	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BC5449	COG1272	protein, Hemolysin III
BC5453	COG1164	Oligoendopeptidase f
BC5455	COG5002	protein histidine kinase activity
BC5458	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BC5460	COG4853	Protein conserved in bacteria
BC5462	COG5002	protein histidine kinase activity
BC5463	COG0745	RESPONSE REGULATOR receiver
BC5472	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BC5473	COG4241	membrane
BC5477	COG0012	GTP binding
BC5478	COG4481	Protein conserved in bacteria
BC5479	COG0668	transmembrane transport
BC5481	COG1475	DNA binding
BC5482	COG1192	Involved in chromosome partitioning
BC5487	COG1847	R3H domain protein
BC5490	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCp0007	COG0187	DNA topoisomerase II activity