locus-tag	class	description
J8Y16_RS00010	COG0592	DNA-directed DNA polymerase activity
J8Y16_RS00015	COG2501	S4 domain
J8Y16_RS00025	COG0187	DNA topoisomerase II activity
J8Y16_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J8Y16_RS00065	COG0516	GMP reductase activity
J8Y16_RS00065	COG0517	IMP dehydrogenase activity
J8Y16_RS00070	COG1686	Belongs to the peptidase S11 family
J8Y16_RS00100	COG1428	Deoxynucleoside kinase
J8Y16_RS00105	COG1428	Deoxynucleoside kinase
J8Y16_RS00110	COG1335	isochorismatase
J8Y16_RS00115	COG0590	tRNA wobble adenosine to inosine editing
J8Y16_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J8Y16_RS00180	COG1982	Orn Lys Arg decarboxylase major
J8Y16_RS00190	COG0470	DNA polymerase III
J8Y16_RS00195	COG1774	PSP1 C-terminal conserved region
J8Y16_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
J8Y16_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J8Y16_RS00220	COG2002	toxin-antitoxin pair type II binding
J8Y16_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Y16_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Y16_RS00230	COG0084	hydrolase, TatD family'
J8Y16_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J8Y16_RS00250	COG4466	Protein conserved in bacteria
J8Y16_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J8Y16_RS00270	COG0251	oxidation-reduction process
J8Y16_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J8Y16_RS00305	COG2002	toxin-antitoxin pair type II binding
J8Y16_RS00310	COG2244	polysaccharide biosynthetic process
J8Y16_RS00315	COG3956	TIGRFAM MazG family protein
J8Y16_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J8Y16_RS00340	COG1098	S1 RNA binding domain
J8Y16_RS00355	COG2208	phosphoserine phosphatase activity
J8Y16_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J8Y16_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J8Y16_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Y16_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J8Y16_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
J8Y16_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y16_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J8Y16_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J8Y16_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J8Y16_RS00420	COG1396	sequence-specific DNA binding
J8Y16_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8Y16_RS00515	COG3880	PFAM UvrB UvrC protein
J8Y16_RS00525	COG0542	response to heat
J8Y16_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J8Y16_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
J8Y16_RS00560	COG1045	serine acetyltransferase
J8Y16_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Y16_RS00580	COG3688	RNA-binding protein containing a PIN domain
J8Y16_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8Y16_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
J8Y16_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J8Y16_RS00625	COG2813	Specifically methylates the guanine in position
J8Y16_RS00640	COG1358	cellular component organization or biogenesis
J8Y16_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
J8Y16_RS00770	COG0201	protein transport
J8Y16_RS00780	COG0024	Methionine aminopeptidase
J8Y16_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J8Y16_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J8Y16_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS00855	COG0489	protein tyrosine kinase activity
J8Y16_RS00865	COG2194	sulfuric ester hydrolase activity
J8Y16_RS00870	COG0726	polysaccharide deacetylase
J8Y16_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
J8Y16_RS00955	COG4856	YbbR-like protein
J8Y16_RS01000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J8Y16_RS01005	COG1506	peptidase
J8Y16_RS01005	COG0823	Involved in the tonB-independent uptake of proteins
J8Y16_RS01005	COG4946	Tricorn protease homolog
J8Y16_RS01035	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS01040	COG2011	ABC-type metal ion transport system permease component
J8Y16_RS01045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J8Y16_RS01050	COG1464	Belongs to the NlpA lipoprotein family
J8Y16_RS01055	COG0604	alcohol dehydrogenase
J8Y16_RS01065	COG0277	FAD linked oxidase domain protein
J8Y16_RS01070	COG2271	Major facilitator Superfamily
J8Y16_RS01080	COG2814	Major facilitator Superfamily
J8Y16_RS01095	COG0601	transmembrane transport
J8Y16_RS01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y16_RS01105	COG0444	Belongs to the ABC transporter superfamily
J8Y16_RS01110	COG4608	Belongs to the ABC transporter superfamily
J8Y16_RS01115	COG4166	transmembrane transport
J8Y16_RS01125	COG2207	Transcriptional regulator
J8Y16_RS01140	COG4166	transmembrane transport
J8Y16_RS01145	COG4166	transmembrane transport
J8Y16_RS01150	COG0656	L-ascorbic acid biosynthetic process
J8Y16_RS01155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y16_RS01170	COG4149	molybdate abc transporter
J8Y16_RS01175	COG0725	ABC transporter, periplasmic molybdate-binding protein
J8Y16_RS01180	COG1910	domain protein
J8Y16_RS01195	COG0697	spore germination
J8Y16_RS01210	COG0204	Acyl-transferase
J8Y16_RS01220	COG1609	Transcriptional regulator
J8Y16_RS01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS01240	COG0084	hydrolase, TatD family'
J8Y16_RS01250	COG5298	Protein conserved in bacteria
J8Y16_RS01275	COG0488	(ABC) transporter
J8Y16_RS01285	COG0747	negative chemotaxis
J8Y16_RS01290	COG0747	negative chemotaxis
J8Y16_RS01295	COG0601	transmembrane transport
J8Y16_RS01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y16_RS01305	COG0444	Belongs to the ABC transporter superfamily
J8Y16_RS01310	COG4608	Belongs to the ABC transporter superfamily
J8Y16_RS01315	COG0561	phosphatase activity
J8Y16_RS01345	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J8Y16_RS01350	COG0179	Fumarylacetoacetate (FAA) hydrolase
J8Y16_RS01360	COG2814	Major facilitator Superfamily
J8Y16_RS01370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J8Y16_RS01380	COG4294	response to UV
J8Y16_RS01385	COG0457	Tetratricopeptide repeat
J8Y16_RS01385	COG0705	Rhomboid family
J8Y16_RS01395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J8Y16_RS01400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8Y16_RS01405	COG0864	Transcriptional regulator
J8Y16_RS01410	COG2337	Toxic component of a toxin-antitoxin (TA) module
J8Y16_RS01415	COG2183	response to ionizing radiation
J8Y16_RS01510	COG0802	atpase or kinase
J8Y16_RS01515	COG1214	PFAM Peptidase M22, glycoprotease
J8Y16_RS01520	COG0456	acetyltransferase
J8Y16_RS01530	COG0488	(ABC) transporter
J8Y16_RS01545	COG1266	CAAX protease self-immunity
J8Y16_RS01585	COG1674	ftsk spoiiie
J8Y16_RS01595	COG2946	Replication initiation factor
J8Y16_RS01630	COG2252	PERMEase
J8Y16_RS01640	COG5002	protein histidine kinase activity
J8Y16_RS01665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J8Y16_RS01735	COG2205	protein histidine kinase activity
J8Y16_RS01740	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS01760	COG0697	spore germination
J8Y16_RS01785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J8Y16_RS01790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J8Y16_RS01795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J8Y16_RS01805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J8Y16_RS01820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J8Y16_RS01830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J8Y16_RS01840	COG0151	Belongs to the GarS family
J8Y16_RS01865	COG0210	DNA helicase
J8Y16_RS01875	COG4851	CamS sex pheromone cAM373 precursor
J8Y16_RS01895	COG1335	isochorismatase
J8Y16_RS01900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J8Y16_RS01905	COG2011	ABC-type metal ion transport system permease component
J8Y16_RS01910	COG1464	Belongs to the NlpA lipoprotein family
J8Y16_RS01925	COG0003	Pfam Anion-transporting ATPase
J8Y16_RS01930	COG1846	Transcriptional regulator
J8Y16_RS01935	COG4682	membrane
J8Y16_RS01955	COG1597	lipid kinase activity
J8Y16_RS01960	COG0546	phosphoglycolate phosphatase activity
J8Y16_RS01965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J8Y16_RS01975	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS01980	COG2076	Multidrug Resistance protein
J8Y16_RS01985	COG2309	aminopeptidase activity
J8Y16_RS02000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS02005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J8Y16_RS02010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J8Y16_RS02015	COG5002	protein histidine kinase activity
J8Y16_RS02020	COG4807	Protein conserved in bacteria
J8Y16_RS02045	COG1757	Na H antiporter
J8Y16_RS02050	COG1473	amidohydrolase
J8Y16_RS02065	COG0450	alkyl hydroperoxide reductase
J8Y16_RS02085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS02090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS02095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS02110	COG0166	Belongs to the GPI family
J8Y16_RS02135	COG5002	protein histidine kinase activity
J8Y16_RS02155	COG3541	Predicted nucleotidyltransferase
J8Y16_RS02160	COG2814	Major facilitator Superfamily
J8Y16_RS02165	COG0723	plastoquinol--plastocyanin reductase activity
J8Y16_RS02165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y16_RS02175	COG0765	amino acid transport
J8Y16_RS02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y16_RS02190	COG0840	transmembrane signaling receptor activity
J8Y16_RS02195	COG0366	Alpha amylase catalytic
J8Y16_RS02200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y16_RS02200	COG1263	PTS System
J8Y16_RS02200	COG2190	(PTS) system
J8Y16_RS02230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
J8Y16_RS02245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y16_RS02255	COG1116	anion transmembrane transporter activity
J8Y16_RS02265	COG0488	(ABC) transporter
J8Y16_RS02315	COG2270	Major facilitator Superfamily
J8Y16_RS02345	COG2310	stress, protein
J8Y16_RS02350	COG2310	stress, protein
J8Y16_RS02355	COG2310	stress, protein
J8Y16_RS02360	COG0861	Integral membrane protein TerC family
J8Y16_RS02370	COG3853	Toxic anion resistance protein (TelA)
J8Y16_RS02385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J8Y16_RS02395	COG1295	ribonuclease BN
J8Y16_RS02400	COG2217	Heavy metal translocating P-type atpase
J8Y16_RS02405	COG0697	spore germination
J8Y16_RS02425	COG0586	Pfam SNARE associated Golgi protein
J8Y16_RS02440	COG3871	stress protein (general stress protein 26)
J8Y16_RS02445	COG0387	Pfam Sodium calcium exchanger
J8Y16_RS02455	COG0535	radical SAM domain protein
J8Y16_RS02475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J8Y16_RS02480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J8Y16_RS02495	COG3829	transcription factor binding
J8Y16_RS02505	COG0833	amino acid
J8Y16_RS02510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Y16_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y16_RS02540	COG1263	PTS System
J8Y16_RS02545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y16_RS02565	COG0463	Glycosyl transferase, family 2
J8Y16_RS02575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y16_RS02575	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J8Y16_RS02595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
J8Y16_RS02615	COG1228	amidohydrolase
J8Y16_RS02620	COG1090	epimerase
J8Y16_RS02650	COG1988	membrane-bound metal-dependent
J8Y16_RS02655	COG1194	a g-specific adenine glycosylase
J8Y16_RS02680	COG1132	(ABC) transporter
J8Y16_RS02685	COG4129	membrane
J8Y16_RS02690	COG0070	glutamate synthase
J8Y16_RS02690	COG0069	glutamate synthase activity
J8Y16_RS02690	COG0067	glutamate synthase
J8Y16_RS02700	COG4555	ABC transporter
J8Y16_RS02720	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J8Y16_RS02725	COG0735	belongs to the Fur family
J8Y16_RS02840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J8Y16_RS02845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J8Y16_RS02855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J8Y16_RS02865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J8Y16_RS02870	COG1716	ATPase activity
J8Y16_RS02870	COG5001	Diguanylate cyclase
J8Y16_RS02875	COG2766	serine protein kinase
J8Y16_RS02895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Y16_RS02905	COG1585	Membrane protein implicated in regulation of membrane protease activity
J8Y16_RS02910	COG2268	Band 7 protein
J8Y16_RS02920	COG3290	protein histidine kinase activity
J8Y16_RS02925	COG4565	transcriptional regulatory protein
J8Y16_RS02930	COG2851	Citrate transporter
J8Y16_RS02950	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J8Y16_RS02955	COG3842	ATPase activity
J8Y16_RS02960	COG1175	transmembrane transport
J8Y16_RS02965	COG0395	ABC-type sugar transport system, permease component
J8Y16_RS02975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J8Y16_RS02980	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS02985	COG5002	protein histidine kinase activity
J8Y16_RS02995	COG4990	cell redox homeostasis
J8Y16_RS03010	COG3290	protein histidine kinase activity
J8Y16_RS03015	COG4565	transcriptional regulatory protein
J8Y16_RS03020	COG3493	citrate carrier protein
J8Y16_RS03025	COG0281	malic enzyme
J8Y16_RS03040	COG0697	spore germination
J8Y16_RS03045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS03055	COG5002	protein histidine kinase activity
J8Y16_RS03060	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS03065	COG0456	acetyltransferase
J8Y16_RS03065	COG0454	-acetyltransferase
J8Y16_RS03070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J8Y16_RS03075	COG3383	formate dehydrogenase (NAD+) activity
J8Y16_RS03080	COG2427	Protein of unknown function (DUF1641)
J8Y16_RS03095	COG0531	amino acid
J8Y16_RS03100	COG0640	Transcriptional regulator
J8Y16_RS03105	COG2217	Heavy metal translocating P-type atpase
J8Y16_RS03110	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J8Y16_RS03125	COG3227	Zinc metalloprotease (Elastase)
J8Y16_RS03145	COG2720	vancomycin resistance protein
J8Y16_RS03150	COG1316	TRANSCRIPTIONal
J8Y16_RS03155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS03160	COG0346	lactoylglutathione lyase activity
J8Y16_RS03165	COG1253	flavin adenine dinucleotide binding
J8Y16_RS03170	COG1027	Aspartate ammonia-lyase
J8Y16_RS03175	COG1620	l-lactate permease
J8Y16_RS03190	COG3104	oligopeptide transport
J8Y16_RS03195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS03200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS03205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS03215	COG2226	methyltransferase
J8Y16_RS03220	COG0156	8-amino-7-oxononanoate synthase activity
J8Y16_RS03225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y16_RS03230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J8Y16_RS03240	COG4548	von Willebrand factor, type A
J8Y16_RS03245	COG0714	Associated with various cellular activities
J8Y16_RS03250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y16_RS03265	COG0531	amino acid
J8Y16_RS03270	COG2188	Transcriptional regulator
J8Y16_RS03275	COG1263	PTS System
J8Y16_RS03275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y16_RS03280	COG0366	Alpha amylase catalytic
J8Y16_RS03295	COG0697	spore germination
J8Y16_RS03305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8Y16_RS03310	COG1115	amino acid carrier protein
J8Y16_RS03315	COG1126	abc transporter atp-binding protein
J8Y16_RS03320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y16_RS03325	COG0765	amino acid transport
J8Y16_RS03330	COG0765	amino acid transport
J8Y16_RS03335	COG0833	amino acid
J8Y16_RS03360	COG2378	regulation of single-species biofilm formation
J8Y16_RS03365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J8Y16_RS03370	COG5002	protein histidine kinase activity
J8Y16_RS03385	COG0659	secondary active sulfate transmembrane transporter activity
J8Y16_RS03400	COG0747	negative chemotaxis
J8Y16_RS03410	COG0601	transmembrane transport
J8Y16_RS03415	COG4608	Belongs to the ABC transporter superfamily
J8Y16_RS03425	COG2271	Major facilitator Superfamily
J8Y16_RS03430	COG1846	Transcriptional regulator
J8Y16_RS03435	COG0477	Major facilitator Superfamily
J8Y16_RS03440	COG1609	Transcriptional regulator
J8Y16_RS03445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J8Y16_RS03460	COG1172	Belongs to the binding-protein-dependent transport system permease family
J8Y16_RS03465	COG1879	ABC-type sugar transport system periplasmic component
J8Y16_RS03485	COG1063	alcohol dehydrogenase
J8Y16_RS03500	COG3568	Endonuclease Exonuclease Phosphatase
J8Y16_RS03530	COG0840	transmembrane signaling receptor activity
J8Y16_RS03535	COG1388	LysM domain
J8Y16_RS03535	COG3584	3D domain protein
J8Y16_RS03540	COG1476	TRANSCRIPTIONal
J8Y16_RS03555	COG3104	oligopeptide transport
J8Y16_RS03560	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS03575	COG1113	amino acid transport
J8Y16_RS03580	COG2252	PERMEase
J8Y16_RS03595	COG2153	protein acetylation
J8Y16_RS03605	COG0569	domain protein
J8Y16_RS03605	COG0475	glutathione-regulated potassium exporter activity
J8Y16_RS03620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J8Y16_RS03625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J8Y16_RS03635	COG4990	cell redox homeostasis
J8Y16_RS03650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y16_RS03655	COG0697	spore germination
J8Y16_RS03660	COG0531	amino acid
J8Y16_RS03670	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Y16_RS03675	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Y16_RS03680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
J8Y16_RS03680	COG1918	ferrous iron import across plasma membrane
J8Y16_RS03685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8Y16_RS03690	COG0573	inorganic phosphate transmembrane transporter activity
J8Y16_RS03695	COG0581	inorganic phosphate transmembrane transporter activity
J8Y16_RS03700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Y16_RS03820	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
J8Y16_RS03840	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J8Y16_RS03845	COG1116	anion transmembrane transporter activity
J8Y16_RS03850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y16_RS03855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y16_RS03860	COG0352	thiamine-phosphate diphosphorylase activity
J8Y16_RS03865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y16_RS03870	COG2104	thiamine diphosphate biosynthetic process
J8Y16_RS03880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y16_RS03885	COG0351	phosphomethylpyrimidine kinase
J8Y16_RS03925	COG2205	protein histidine kinase activity
J8Y16_RS03930	COG2814	Major facilitator Superfamily
J8Y16_RS03935	COG1846	Transcriptional regulator
J8Y16_RS03960	COG1136	(ABC) transporter
J8Y16_RS03960	COG0577	efflux transmembrane transporter activity
J8Y16_RS03970	COG2252	PERMEase
J8Y16_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS03980	COG1376	ErfK ybiS ycfS ynhG family protein
J8Y16_RS03995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y16_RS04035	COG0778	Nitroreductase
J8Y16_RS04040	COG2719	SpoVR family
J8Y16_RS04065	COG0446	pyridine nucleotide-disulphide oxidoreductase
J8Y16_RS04070	COG1937	Protein conserved in bacteria
J8Y16_RS04075	COG0425	Belongs to the sulfur carrier protein TusA family
J8Y16_RS04075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y16_RS04080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y16_RS04080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS04085	COG0425	Belongs to the sulfur carrier protein TusA family
J8Y16_RS04090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y16_RS04100	COG2210	Belongs to the sulfur carrier protein TusA family
J8Y16_RS04105	COG0730	response to heat
J8Y16_RS04115	COG1316	TRANSCRIPTIONal
J8Y16_RS04120	COG0604	alcohol dehydrogenase
J8Y16_RS04125	COG1283	sodium-dependent phosphate transmembrane transporter activity
J8Y16_RS04140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Y16_RS04140	COG3711	transcriptional antiterminator
J8Y16_RS04145	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y16_RS04150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y16_RS04175	COG3584	3D domain protein
J8Y16_RS04175	COG1388	LysM domain
J8Y16_RS04180	COG0577	efflux transmembrane transporter activity
J8Y16_RS04185	COG1136	(ABC) transporter
J8Y16_RS04195	COG5522	Integral membrane protein (intg_mem_TP0381)
J8Y16_RS04210	COG0577	efflux transmembrane transporter activity
J8Y16_RS04220	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS04225	COG3546	catalase activity
J8Y16_RS04260	COG0586	Pfam SNARE associated Golgi protein
J8Y16_RS04295	COG0531	amino acid
J8Y16_RS04300	COG0475	glutathione-regulated potassium exporter activity
J8Y16_RS04310	COG1737	Transcriptional regulator
J8Y16_RS04320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y16_RS04320	COG1263	PTS System
J8Y16_RS04330	COG2259	Doxx family
J8Y16_RS04350	COG1522	sequence-specific DNA binding
J8Y16_RS04365	COG2076	Multidrug Resistance protein
J8Y16_RS04370	COG1309	transcriptional regulator
J8Y16_RS04375	COG2814	Major facilitator Superfamily
J8Y16_RS04380	COG4533	DNA binding
J8Y16_RS04385	COG2211	Major facilitator Superfamily
J8Y16_RS04395	COG0693	protein deglycase activity
J8Y16_RS04400	COG0753	catalase activity
J8Y16_RS04410	COG0531	amino acid
J8Y16_RS04425	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS04430	COG1132	(ABC) transporter
J8Y16_RS04435	COG1132	(ABC) transporter
J8Y16_RS04440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y16_RS04445	COG0765	amino acid transport
J8Y16_RS04450	COG1126	abc transporter atp-binding protein
J8Y16_RS04465	COG0189	ligase activity
J8Y16_RS04495	COG0028	Belongs to the TPP enzyme family
J8Y16_RS04500	COG3527	Alpha-acetolactate decarboxylase
J8Y16_RS04510	COG0561	phosphatase activity
J8Y16_RS04515	COG5632	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS04515	COG3409	Peptidoglycan-binding domain 1 protein
J8Y16_RS04520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8Y16_RS04540	COG0659	secondary active sulfate transmembrane transporter activity
J8Y16_RS04555	COG0653	protein targeting
J8Y16_RS04560	COG2244	polysaccharide biosynthetic process
J8Y16_RS04570	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS04575	COG4196	transglutaminase domain protein
J8Y16_RS04595	COG1024	Enoyl-CoA hydratase
J8Y16_RS04620	COG1363	Peptidase, m42
J8Y16_RS04640	COG3938	Belongs to the proline racemase family
J8Y16_RS04685	COG0601	transmembrane transport
J8Y16_RS04690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y16_RS04695	COG0444	Belongs to the ABC transporter superfamily
J8Y16_RS04700	COG4608	Belongs to the ABC transporter superfamily
J8Y16_RS04730	COG0477	Major facilitator Superfamily
J8Y16_RS04735	COG3290	protein histidine kinase activity
J8Y16_RS04740	COG4565	transcriptional regulatory protein
J8Y16_RS04745	COG3181	Tripartite tricarboxylate transporter family receptor
J8Y16_RS04805	COG0305	Participates in initiation and elongation during chromosome replication
J8Y16_RS04895	COG1183	phosphatidylcholine synthase activity
J8Y16_RS04950	COG2376	Dihydroxyacetone kinase
J8Y16_RS04960	COG2376	Dihydroxyacetone kinase
J8Y16_RS04965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J8Y16_RS04970	COG1959	2 iron, 2 sulfur cluster binding
J8Y16_RS04990	COG2770	Histidine kinase
J8Y16_RS04990	COG3437	response regulator, receiver
J8Y16_RS05040	COG3237	CsbD-like
J8Y16_RS05065	COG1191	sigma factor activity
J8Y16_RS05075	COG2208	phosphoserine phosphatase activity
J8Y16_RS05080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J8Y16_RS05085	COG0784	Response regulator, receiver
J8Y16_RS05085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y16_RS05085	COG2198	Histidine kinase
J8Y16_RS05085	COG2205	protein histidine kinase activity
J8Y16_RS05115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y16_RS05120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8Y16_RS05145	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS05150	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J8Y16_RS05155	COG0778	Nitroreductase
J8Y16_RS05185	COG0420	3'-5' exonuclease activity
J8Y16_RS05240	COG0346	lactoylglutathione lyase activity
J8Y16_RS05245	COG0346	lactoylglutathione lyase activity
J8Y16_RS05250	COG0457	Tetratricopeptide repeat
J8Y16_RS05260	COG2267	carboxylic ester hydrolase activity
J8Y16_RS05280	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
J8Y16_RS05285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J8Y16_RS05295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J8Y16_RS05340	COG0477	Major facilitator Superfamily
J8Y16_RS05345	COG0477	Major facilitator Superfamily
J8Y16_RS05355	COG3973	AAA domain
J8Y16_RS05360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8Y16_RS05380	COG4980	gas vesicle protein
J8Y16_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
J8Y16_RS05390	COG1131	(ABC) transporter
J8Y16_RS05395	COG4473	ABC transporter
J8Y16_RS05455	COG1309	transcriptional regulator
J8Y16_RS05465	COG3402	PFAM membrane-flanked domain
J8Y16_RS05470	COG3428	Bacterial PH domain
J8Y16_RS05510	COG3402	PFAM membrane-flanked domain
J8Y16_RS05515	COG3428	Bacterial PH domain
J8Y16_RS05520	COG2329	Antibiotic biosynthesis monooxygenase
J8Y16_RS05525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y16_RS05540	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J8Y16_RS05565	COG1309	transcriptional regulator
J8Y16_RS05570	COG1511	domain protein
J8Y16_RS05585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS05595	COG2378	regulation of single-species biofilm formation
J8Y16_RS05600	COG1609	Transcriptional regulator
J8Y16_RS05610	COG1234	tRNA 3'-trailer cleavage
J8Y16_RS05615	COG0095	Lipoate-protein ligase
J8Y16_RS05625	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS05670	COG1408	metallophosphoesterase
J8Y16_RS05675	COG1078	dGTPase activity
J8Y16_RS05685	COG1595	DNA-templated transcription, initiation
J8Y16_RS05690	COG2207	Transcriptional regulator
J8Y16_RS05690	COG3708	Transcriptional regulator
J8Y16_RS05695	COG2205	protein histidine kinase activity
J8Y16_RS05700	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS05720	COG0501	Belongs to the peptidase M48B family
J8Y16_RS05725	COG0840	transmembrane signaling receptor activity
J8Y16_RS05730	COG0697	spore germination
J8Y16_RS05750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J8Y16_RS05755	COG2224	Isocitrate lyase
J8Y16_RS05765	COG1278	Cold shock
J8Y16_RS05780	COG4903	ComK protein
J8Y16_RS05785	COG0398	Pfam SNARE associated Golgi protein
J8Y16_RS05845	COG0179	Fumarylacetoacetate (FAA) hydrolase
J8Y16_RS05870	COG0367	asparagine synthase
J8Y16_RS05880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J8Y16_RS05885	COG0753	catalase activity
J8Y16_RS05890	COG0004	ammonium transporteR
J8Y16_RS05910	COG2996	Protein conserved in bacteria
J8Y16_RS05920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8Y16_RS05930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS05945	COG0561	phosphatase activity
J8Y16_RS05955	COG0542	response to heat
J8Y16_RS05965	COG2267	carboxylic ester hydrolase activity
J8Y16_RS05990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y16_RS05995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J8Y16_RS06000	COG5504	Zn-dependent protease
J8Y16_RS06010	COG0180	Tryptophanyl-tRNA synthetase
J8Y16_RS06020	COG4166	transmembrane transport
J8Y16_RS06025	COG0601	transmembrane transport
J8Y16_RS06030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J8Y16_RS06035	COG0444	Belongs to the ABC transporter superfamily
J8Y16_RS06040	COG4608	Belongs to the ABC transporter superfamily
J8Y16_RS06045	COG0534	Mate efflux family protein
J8Y16_RS06050	COG4166	transmembrane transport
J8Y16_RS06065	COG0861	Integral membrane protein TerC family
J8Y16_RS06070	COG4862	establishment of competence for transformation
J8Y16_RS06075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y16_RS06085	COG1164	Oligoendopeptidase f
J8Y16_RS06100	COG2346	COG2346, Truncated hemoglobins
J8Y16_RS06105	COG4116	CYTH
J8Y16_RS06115	COG2357	RelA SpoT domain protein
J8Y16_RS06125	COG0564	pseudouridine synthase activity
J8Y16_RS06140	COG0772	Belongs to the SEDS family
J8Y16_RS06145	COG1216	Glycosyl transferase, family 2
J8Y16_RS06165	COG0457	Tetratricopeptide repeat
J8Y16_RS06165	COG0463	Glycosyl transferase, family 2
J8Y16_RS06185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J8Y16_RS06200	COG1091	dTDP-4-dehydrorhamnose reductase activity
J8Y16_RS06245	COG2153	protein acetylation
J8Y16_RS06255	COG2382	esterase
J8Y16_RS06270	COG5492	domain, Protein
J8Y16_RS06275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y16_RS06285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J8Y16_RS06285	COG0512	Glutamine amidotransferase of anthranilate synthase
J8Y16_RS06320	COG1620	l-lactate permease
J8Y16_RS06325	COG5634	Uncharacterized conserved protein (DUF2278)
J8Y16_RS06380	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y16_RS06390	COG1476	TRANSCRIPTIONal
J8Y16_RS06450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y16_RS06465	COG4152	abc transporter atp-binding protein
J8Y16_RS06470	COG1668	transmembrane transport
J8Y16_RS06505	COG4974	Belongs to the 'phage' integrase family
J8Y16_RS06520	COG2226	methyltransferase
J8Y16_RS06530	COG1686	Belongs to the peptidase S11 family
J8Y16_RS06535	COG0681	Belongs to the peptidase S26 family
J8Y16_RS06570	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS06580	COG1176	ABC-type spermidine putrescine transport system, permease component I
J8Y16_RS06585	COG1177	transmembrane transport
J8Y16_RS06590	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J8Y16_RS06600	COG2409	Drug exporters of the RND superfamily
J8Y16_RS06610	COG0564	pseudouridine synthase activity
J8Y16_RS06625	COG2340	Cysteine-rich secretory protein family
J8Y16_RS06630	COG0247	lactate metabolic process
J8Y16_RS06635	COG0277	FAD linked oxidase domain protein
J8Y16_RS06640	COG3835	regulator
J8Y16_RS06650	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS06655	COG5002	protein histidine kinase activity
J8Y16_RS06660	COG2186	Transcriptional regulator
J8Y16_RS06680	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
J8Y16_RS06690	COG2116	formate transmembrane transporter activity
J8Y16_RS06695	COG0861	Integral membrane protein TerC family
J8Y16_RS06700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Y16_RS06710	COG2030	dehydratase
J8Y16_RS06730	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS06735	COG3243	poly(R)-hydroxyalkanoic acid synthase
J8Y16_RS06740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y16_RS06745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Y16_RS06760	COG1840	ABC-type Fe3 transport system, periplasmic component
J8Y16_RS06765	COG3842	ATPase activity
J8Y16_RS06790	COG1349	DNA-binding transcription factor activity
J8Y16_RS06800	COG0235	Class ii aldolase
J8Y16_RS06810	COG2861	carbohydrate metabolic process
J8Y16_RS06820	COG3852	Histidine kinase
J8Y16_RS06825	COG1846	Transcriptional regulator
J8Y16_RS06835	COG2318	DinB family
J8Y16_RS06840	COG5002	protein histidine kinase activity
J8Y16_RS06850	COG0720	synthase
J8Y16_RS06865	COG4873	Protein conserved in bacteria
J8Y16_RS06895	COG1780	Probably involved in ribonucleotide reductase function
J8Y16_RS06930	COG1725	Transcriptional regulator
J8Y16_RS06935	COG1131	(ABC) transporter
J8Y16_RS06945	COG1131	(ABC) transporter
J8Y16_RS06950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J8Y16_RS06965	COG1522	sequence-specific DNA binding
J8Y16_RS06975	COG1335	isochorismatase
J8Y16_RS06985	COG1619	proteins homologs of microcin C7 resistance protein MccF
J8Y16_RS06990	COG2070	2-Nitropropane dioxygenase
J8Y16_RS06995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J8Y16_RS07005	COG1696	Membrane protein involved in D-alanine export
J8Y16_RS07030	COG0716	FMN binding
J8Y16_RS07065	COG0534	Mate efflux family protein
J8Y16_RS07070	COG1968	undecaprenyl-diphosphatase activity
J8Y16_RS07085	COG1846	Transcriptional regulator
J8Y16_RS07095	COG1301	dicarboxylic acid transport
J8Y16_RS07100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J8Y16_RS07105	COG4709	membrane
J8Y16_RS07110	COG3874	Sporulation protein YtfJ
J8Y16_RS07135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y16_RS07140	COG0028	Belongs to the TPP enzyme family
J8Y16_RS07145	COG0440	acetolactate synthase activity
J8Y16_RS07220	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J8Y16_RS07235	COG1183	phosphatidylcholine synthase activity
J8Y16_RS07240	COG1368	sulfuric ester hydrolase activity
J8Y16_RS07250	COG0019	diaminopimelate decarboxylase activity
J8Y16_RS07270	COG0529	Catalyzes the synthesis of activated sulfate
J8Y16_RS07275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8Y16_RS07295	COG1648	precorrin-2 dehydrogenase activity
J8Y16_RS07300	COG0733	neurotransmitter:sodium symporter activity
J8Y16_RS07320	COG1757	Na H antiporter
J8Y16_RS07335	COG4758	membrane
J8Y16_RS07340	COG4585	Histidine kinase
J8Y16_RS07345	COG2197	response regulator
J8Y16_RS07355	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS07365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J8Y16_RS07405	COG0730	response to heat
J8Y16_RS07410	COG0306	phosphate transporter
J8Y16_RS07415	COG1392	Phosphate transport regulator
J8Y16_RS07420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y16_RS07435	COG3852	Histidine kinase
J8Y16_RS07440	COG1801	Protein of unknown function DUF72
J8Y16_RS07450	COG0582	viral genome integration into host DNA
J8Y16_RS07455	COG5002	protein histidine kinase activity
J8Y16_RS07475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J8Y16_RS07475	COG0392	lysyltransferase activity
J8Y16_RS07490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8Y16_RS07495	COG1686	Belongs to the peptidase S11 family
J8Y16_RS07500	COG2715	membrane protein required for spore maturation
J8Y16_RS07505	COG0700	Nucleoside recognition
J8Y16_RS07510	COG1187	pseudouridine synthase activity
J8Y16_RS07520	COG1333	cytochrome c biogenesis protein
J8Y16_RS07525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Y16_RS07530	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS07535	COG5002	protein histidine kinase activity
J8Y16_RS07540	COG2096	Adenosyltransferase
J8Y16_RS07545	COG4942	peptidase
J8Y16_RS07555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
J8Y16_RS07565	COG1141	Ferredoxin
J8Y16_RS07575	COG0514	ATP-dependent DNA helicase (RecQ)
J8Y16_RS07580	COG1266	CAAX protease self-immunity
J8Y16_RS07590	COG1408	metallophosphoesterase
J8Y16_RS07600	COG4862	establishment of competence for transformation
J8Y16_RS07605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J8Y16_RS07625	COG0492	ferredoxin-NADP+ reductase activity
J8Y16_RS07630	COG0252	asparaginase activity
J8Y16_RS07700	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8Y16_RS07715	COG0142	geranyltranstransferase activity
J8Y16_RS07725	COG0142	geranyltranstransferase activity
J8Y16_RS07745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J8Y16_RS07750	COG0457	Tetratricopeptide repeat
J8Y16_RS07770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J8Y16_RS07780	COG4347	Protein of unknown function (DUF1405)
J8Y16_RS07795	COG2738	Putative neutral zinc metallopeptidase
J8Y16_RS07805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS07810	COG1694	Mazg nucleotide pyrophosphohydrolase
J8Y16_RS07825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J8Y16_RS07830	COG0438	transferase activity, transferring glycosyl groups
J8Y16_RS07865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J8Y16_RS07865	COG1199	ATP-dependent helicase activity
J8Y16_RS07885	COG3935	DnaD domain protein
J8Y16_RS07890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J8Y16_RS07900	COG4499	WXG100 protein secretion system (Wss), protein YukC
J8Y16_RS07900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y16_RS07960	COG0116	Belongs to the methyltransferase superfamily
J8Y16_RS07970	COG1199	ATP-dependent helicase activity
J8Y16_RS07975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
J8Y16_RS07985	COG3173	Aminoglycoside phosphotransferase
J8Y16_RS07990	COG0024	Methionine aminopeptidase
J8Y16_RS08000	COG2233	PERMEase
J8Y16_RS08005	COG2311	Membrane
J8Y16_RS08010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8Y16_RS08020	COG0456	acetyltransferase
J8Y16_RS08060	COG0754	glutathionylspermidine amidase activity
J8Y16_RS08075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y16_RS08090	COG0454	-acetyltransferase
J8Y16_RS08110	COG0328	RNA-DNA hybrid ribonuclease activity
J8Y16_RS08145	COG3403	YqcI/YcgG family
J8Y16_RS08150	COG1280	lysine exporter protein (LysE YggA)
J8Y16_RS08165	COG3162	membrane
J8Y16_RS08170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y16_RS08175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y16_RS08185	COG0475	glutathione-regulated potassium exporter activity
J8Y16_RS08190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J8Y16_RS08195	COG4978	Transcriptional regulator
J8Y16_RS08195	COG0789	Transcriptional regulator
J8Y16_RS08205	COG2323	membrane
J8Y16_RS08210	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J8Y16_RS08265	COG1923	regulation of RNA biosynthetic process
J8Y16_RS08275	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8Y16_RS08280	COG1360	Flagellar Motor Protein
J8Y16_RS08285	COG2201	protein-glutamate methylesterase activity
J8Y16_RS08290	COG0643	Histidine kinase
J8Y16_RS08290	COG2198	Histidine kinase
J8Y16_RS08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y16_RS08295	COG1776	CheC inhibitor of MCP methylation
J8Y16_RS08310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J8Y16_RS08330	COG1256	bacterial-type flagellum assembly
J8Y16_RS08335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Y16_RS08340	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
J8Y16_RS08355	COG1815	bacterial-type flagellum-dependent cell motility
J8Y16_RS08360	COG1558	bacterial-type flagellum-dependent cell motility
J8Y16_RS08370	COG1766	The M ring may be actively involved in energy transduction
J8Y16_RS08375	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y16_RS08385	COG1157	protein secretion by the type III secretion system
J8Y16_RS08425	COG0835	chemotaxis
J8Y16_RS08425	COG0784	Response regulator, receiver
J8Y16_RS08435	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Y16_RS08440	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J8Y16_RS08445	COG0741	lytic transglycosylase activity
J8Y16_RS08455	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y16_RS08460	COG1776	CheC inhibitor of MCP methylation
J8Y16_RS08460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J8Y16_RS08470	COG1338	Plays a role in the flagellum-specific transport system
J8Y16_RS08475	COG1987	bacterial-type flagellum assembly
J8Y16_RS08485	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J8Y16_RS08490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J8Y16_RS08495	COG1419	protein localization to endoplasmic reticulum
J8Y16_RS08500	COG4786	Flagellar basal body rod
J8Y16_RS08505	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J8Y16_RS08550	COG2329	Antibiotic biosynthesis monooxygenase
J8Y16_RS08575	COG0583	DNA-binding transcription factor activity
J8Y16_RS08580	COG3842	ATPase activity
J8Y16_RS08585	COG0725	ABC transporter, periplasmic molybdate-binding protein
J8Y16_RS08595	COG1234	tRNA 3'-trailer cleavage
J8Y16_RS08625	COG1686	Belongs to the peptidase S11 family
J8Y16_RS08655	COG1846	Transcriptional regulator
J8Y16_RS08665	COG0367	asparagine synthase
J8Y16_RS08695	COG1802	Transcriptional regulator
J8Y16_RS08700	COG0697	spore germination
J8Y16_RS08705	COG0523	cobalamin synthesis protein
J8Y16_RS08710	COG0701	Predicted permease
J8Y16_RS08725	COG1757	Na H antiporter
J8Y16_RS08730	COG0114	fumarate hydratase activity
J8Y16_RS08745	COG0534	Mate efflux family protein
J8Y16_RS08750	COG3340	Belongs to the peptidase S51 family
J8Y16_RS08770	COG0785	Cytochrome C biogenesis protein
J8Y16_RS08800	COG2733	membrane
J8Y16_RS08835	COG1131	(ABC) transporter
J8Y16_RS08850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y16_RS08855	COG0528	UMP kinase activity
J8Y16_RS08865	COG1027	Aspartate ammonia-lyase
J8Y16_RS08870	COG0281	malic enzyme
J8Y16_RS08875	COG4191	Histidine kinase
J8Y16_RS08880	COG0784	Response regulator, receiver
J8Y16_RS08885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J8Y16_RS08935	COG1051	belongs to the nudix hydrolase family
J8Y16_RS08950	COG2814	Major facilitator Superfamily
J8Y16_RS08965	COG1966	Carbon starvation protein
J8Y16_RS08975	COG1695	Transcriptional regulator
J8Y16_RS08985	COG0477	Major facilitator Superfamily
J8Y16_RS08990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y16_RS08995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J8Y16_RS09000	COG4166	transmembrane transport
J8Y16_RS09005	COG2223	nitrite transmembrane transporter activity
J8Y16_RS09010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Y16_RS09025	COG2244	polysaccharide biosynthetic process
J8Y16_RS09030	COG0733	neurotransmitter:sodium symporter activity
J8Y16_RS09040	COG5566	PFAM Mor transcription activator
J8Y16_RS09045	COG2323	membrane
J8Y16_RS09060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Y16_RS09065	COG2132	Multicopper oxidase
J8Y16_RS09075	COG5002	protein histidine kinase activity
J8Y16_RS09080	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS09090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y16_RS09095	COG0028	Belongs to the TPP enzyme family
J8Y16_RS09100	COG0440	acetolactate synthase activity
J8Y16_RS09105	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J8Y16_RS09115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J8Y16_RS09140	COG2814	Major facilitator Superfamily
J8Y16_RS09145	COG3384	dioxygenase
J8Y16_RS09155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J8Y16_RS09160	COG3279	Response regulator of the LytR AlgR family
J8Y16_RS09165	COG0427	acetyl-CoA hydrolase
J8Y16_RS09185	COG4166	transmembrane transport
J8Y16_RS09220	COG0535	radical SAM domain protein
J8Y16_RS09225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS09245	COG1914	H( )-stimulated, divalent metal cation uptake system
J8Y16_RS09260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J8Y16_RS09265	COG0531	amino acid
J8Y16_RS09290	COG2390	Transcriptional regulator
J8Y16_RS09300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS09305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J8Y16_RS09335	COG0006	proline dipeptidase activity
J8Y16_RS09340	COG2132	Multicopper oxidase
J8Y16_RS09360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Y16_RS09375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J8Y16_RS09380	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS09390	COG2372	response to copper ion
J8Y16_RS09390	COG1276	copper resistance
J8Y16_RS09395	COG4549	nuclear export factor GLE1
J8Y16_RS09400	COG0697	spore germination
J8Y16_RS09405	COG0583	DNA-binding transcription factor activity
J8Y16_RS09410	COG1959	2 iron, 2 sulfur cluster binding
J8Y16_RS09415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J8Y16_RS09420	COG0778	Nitroreductase
J8Y16_RS09435	COG0628	permease
J8Y16_RS09450	COG1231	oxidoreductase activity
J8Y16_RS09455	COG0523	cobalamin synthesis protein
J8Y16_RS09470	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS09475	COG2030	dehydratase
J8Y16_RS09480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y16_RS09490	COG0411	ABC transporter
J8Y16_RS09510	COG0583	DNA-binding transcription factor activity
J8Y16_RS09520	COG1942	4-Oxalocrotonate Tautomerase
J8Y16_RS09540	COG1271	oxidase subunit
J8Y16_RS09545	COG1294	oxidase, subunit
J8Y16_RS09550	COG4988	ABC transporter
J8Y16_RS09555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J8Y16_RS09575	COG1686	Belongs to the peptidase S11 family
J8Y16_RS09590	COG1388	LysM domain
J8Y16_RS09590	COG0791	NLP P60 protein
J8Y16_RS09600	COG1132	(ABC) transporter
J8Y16_RS09605	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS09610	COG5002	protein histidine kinase activity
J8Y16_RS09620	COG0300	oxidoreductase activity
J8Y16_RS09625	COG4122	O-methyltransferase activity
J8Y16_RS09640	COG5658	integral membrane protein
J8Y16_RS09655	COG0460	homoserine dehydrogenase
J8Y16_RS09680	COG1316	TRANSCRIPTIONal
J8Y16_RS09690	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS09695	COG5002	protein histidine kinase activity
J8Y16_RS09710	COG1285	pathogenesis
J8Y16_RS09715	COG1247	-acetyltransferase
J8Y16_RS09735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y16_RS09745	COG1082	Xylose isomerase domain protein TIM barrel
J8Y16_RS09755	COG2814	Major facilitator Superfamily
J8Y16_RS09760	COG1279	arginine transmembrane transporter activity
J8Y16_RS09770	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8Y16_RS09805	COG0577	efflux transmembrane transporter activity
J8Y16_RS09810	COG2002	toxin-antitoxin pair type II binding
J8Y16_RS09815	COG1404	Belongs to the peptidase S8 family
J8Y16_RS09820	COG0640	Transcriptional regulator
J8Y16_RS09825	COG0667	Aldo Keto reductase
J8Y16_RS09830	COG2814	Major facilitator Superfamily
J8Y16_RS09855	COG0840	transmembrane signaling receptor activity
J8Y16_RS09870	COG3949	Membrane
J8Y16_RS09875	COG0783	Belongs to the Dps family
J8Y16_RS09890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J8Y16_RS09900	COG1231	oxidoreductase activity
J8Y16_RS09910	COG4989	oxidoreductase activity
J8Y16_RS09915	COG0523	cobalamin synthesis protein
J8Y16_RS09920	COG0456	acetyltransferase
J8Y16_RS09935	COG0803	Belongs to the bacterial solute-binding protein 9 family
J8Y16_RS09935	COG3443	Belongs to the bacterial solute-binding protein 9 family
J8Y16_RS09945	COG0702	epimerase
J8Y16_RS09955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J8Y16_RS09965	COG4166	transmembrane transport
J8Y16_RS09980	COG0406	alpha-ribazole phosphatase activity
J8Y16_RS09990	COG5337	Spore coat protein CotH
J8Y16_RS09995	COG1051	belongs to the nudix hydrolase family
J8Y16_RS10000	COG0586	Pfam SNARE associated Golgi protein
J8Y16_RS10005	COG2244	polysaccharide biosynthetic process
J8Y16_RS10015	COG0701	Predicted permease
J8Y16_RS10020	COG3689	TIGRFAM TIGR03943 family protein
J8Y16_RS10025	COG1607	acyl-coa hydrolase
J8Y16_RS10035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y16_RS10050	COG0702	epimerase
J8Y16_RS10055	COG2839	Protein conserved in bacteria
J8Y16_RS10060	COG1253	flavin adenine dinucleotide binding
J8Y16_RS10075	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS10080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Y16_RS10100	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS10110	COG1876	peptidase activity
J8Y16_RS10120	COG0154	amidase activity
J8Y16_RS10125	COG2211	Major facilitator Superfamily
J8Y16_RS10140	COG2368	4-hydroxyphenylacetate
J8Y16_RS10150	COG0196	riboflavin kinase activity
J8Y16_RS10165	COG0251	oxidation-reduction process
J8Y16_RS10175	COG3971	2-oxopent-4-enoate hydratase activity
J8Y16_RS10195	COG1942	4-Oxalocrotonate Tautomerase
J8Y16_RS10205	COG0561	phosphatase activity
J8Y16_RS10215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J8Y16_RS10235	COG1819	glycosyl
J8Y16_RS10240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS10275	COG0456	acetyltransferase
J8Y16_RS10300	COG3874	Sporulation protein YtfJ
J8Y16_RS10325	COG2226	methyltransferase
J8Y16_RS10350	COG0346	lactoylglutathione lyase activity
J8Y16_RS10360	COG0604	alcohol dehydrogenase
J8Y16_RS10365	COG1595	DNA-templated transcription, initiation
J8Y16_RS10380	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J8Y16_RS10390	COG0426	domain, Protein
J8Y16_RS10390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8Y16_RS10400	COG0386	Belongs to the glutathione peroxidase family
J8Y16_RS10405	COG1305	Transglutaminase-like
J8Y16_RS10410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
J8Y16_RS10415	COG0714	Associated with various cellular activities
J8Y16_RS10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J8Y16_RS10435	COG1140	nitrate reductase beta subunit
J8Y16_RS10440	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J8Y16_RS10445	COG2181	nitrate reductase activity
J8Y16_RS10450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Y16_RS10455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J8Y16_RS10460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y16_RS10465	COG0303	'Molybdopterin
J8Y16_RS10470	COG0314	molybdopterin synthase activity
J8Y16_RS10480	COG2223	nitrite transmembrane transporter activity
J8Y16_RS10490	COG1648	precorrin-2 dehydrogenase activity
J8Y16_RS10500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J8Y16_RS10500	COG1587	Uroporphyrinogen-III synthase
J8Y16_RS10505	COG2146	nitrite reductase [NAD(P)H] activity
J8Y16_RS10510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J8Y16_RS10515	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
J8Y16_RS10550	COG2359	stage V sporulation protein S
J8Y16_RS10580	COG1418	mRNA catabolic process
J8Y16_RS10585	COG0488	(ABC) transporter
J8Y16_RS10600	COG0629	single-stranded DNA binding
J8Y16_RS10615	COG1413	lyase activity
J8Y16_RS10630	COG2136	Putative SAM-dependent methyltransferase
J8Y16_RS10630	COG2521	methyltransferase
J8Y16_RS10660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J8Y16_RS10680	COG0017	Asparaginyl-tRNA synthetase
J8Y16_RS10700	COG1674	ftsk spoiiie
J8Y16_RS10775	COG1929	Belongs to the glycerate kinase type-1 family
J8Y16_RS10780	COG0471	metal ion transport
J8Y16_RS10785	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS10790	COG5002	protein histidine kinase activity
J8Y16_RS10790	COG3850	Histidine kinase
J8Y16_RS10805	COG0733	neurotransmitter:sodium symporter activity
J8Y16_RS10830	COG2610	gluconate transmembrane transporter activity
J8Y16_RS10835	COG1454	alcohol dehydrogenase
J8Y16_RS10840	COG1794	racemase activity, acting on amino acids and derivatives
J8Y16_RS10850	COG0456	acetyltransferase
J8Y16_RS10855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J8Y16_RS10865	COG1131	(ABC) transporter
J8Y16_RS10870	COG4473	ABC transporter
J8Y16_RS10880	COG0546	phosphoglycolate phosphatase activity
J8Y16_RS10900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y16_RS10905	COG3250	beta-galactosidase activity
J8Y16_RS10920	COG0768	penicillin binding
J8Y16_RS10930	COG0204	Acyl-transferase
J8Y16_RS10935	COG1272	protein, Hemolysin III
J8Y16_RS10945	COG0805	protein transport
J8Y16_RS10955	COG1307	EDD domain protein, DegV family
J8Y16_RS10960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J8Y16_RS10965	COG1999	signal sequence binding
J8Y16_RS10970	COG0071	Belongs to the small heat shock protein (HSP20) family
J8Y16_RS10975	COG0367	asparagine synthase
J8Y16_RS10995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS11000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J8Y16_RS11020	COG1335	isochorismatase
J8Y16_RS11025	COG0071	Belongs to the small heat shock protein (HSP20) family
J8Y16_RS11030	COG0668	transmembrane transport
J8Y16_RS11035	COG4585	Histidine kinase
J8Y16_RS11035	COG2203	Gaf domain
J8Y16_RS11040	COG2197	response regulator
J8Y16_RS11050	COG1064	alcohol dehydrogenase
J8Y16_RS11075	COG1070	Carbohydrate kinase
J8Y16_RS11080	COG1070	Carbohydrate kinase
J8Y16_RS11110	COG1125	glycine betaine transport
J8Y16_RS11110	COG0517	IMP dehydrogenase activity
J8Y16_RS11115	COG1174	glycine betaine transport
J8Y16_RS11150	COG1253	flavin adenine dinucleotide binding
J8Y16_RS11155	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS11160	COG5506	Protein of unknown function (DUF1694)
J8Y16_RS11175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y16_RS11180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J8Y16_RS11185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J8Y16_RS11190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Y16_RS11195	COG0456	acetyltransferase
J8Y16_RS11200	COG3829	transcription factor binding
J8Y16_RS11205	COG1509	lysine 2,3-aminomutase activity
J8Y16_RS11240	COG0515	serine threonine protein kinase
J8Y16_RS11240	COG3064	Membrane
J8Y16_RS11240	COG4991	sh3 domain protein
J8Y16_RS11245	COG4326	sporulation control protein
J8Y16_RS11250	COG0671	phosphoesterase, PA-phosphatase related
J8Y16_RS11255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J8Y16_RS11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y16_RS11325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J8Y16_RS11360	COG0300	oxidoreductase activity
J8Y16_RS11380	COG4499	WXG100 protein secretion system (Wss), protein YukC
J8Y16_RS11380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y16_RS11385	COG2814	Major facilitator Superfamily
J8Y16_RS11390	COG4841	protein insertion into membrane
J8Y16_RS11395	COG0372	Belongs to the citrate synthase family
J8Y16_RS11400	COG2079	MmgE PrpD family protein
J8Y16_RS11405	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
J8Y16_RS11410	COG1960	acyl-CoA dehydrogenase activity
J8Y16_RS11415	COG2084	Dehydrogenase
J8Y16_RS11425	COG1280	lysine exporter protein (LysE YggA)
J8Y16_RS11430	COG1024	Enoyl-CoA hydratase
J8Y16_RS11445	COG0420	3'-5' exonuclease activity
J8Y16_RS11450	COG0419	ATPase involved in DNA repair
J8Y16_RS11465	COG2223	nitrite transmembrane transporter activity
J8Y16_RS11470	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS11475	COG1169	isochorismate synthase
J8Y16_RS11480	COG1021	2,3-dihydroxybenzoate-AMP ligase
J8Y16_RS11485	COG1535	isochorismatase
J8Y16_RS11485	COG3433	isochorismatase activity
J8Y16_RS11490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J8Y16_RS11495	COG3251	PFAM MbtH domain protein
J8Y16_RS11500	COG2814	Major facilitator Superfamily
J8Y16_RS11515	COG0776	regulation of translation
J8Y16_RS11525	COG2318	DinB family
J8Y16_RS11535	COG1115	amino acid carrier protein
J8Y16_RS11555	COG2329	Antibiotic biosynthesis monooxygenase
J8Y16_RS11560	COG1187	pseudouridine synthase activity
J8Y16_RS11565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J8Y16_RS11570	COG1136	(ABC) transporter
J8Y16_RS11580	COG0596	Alpha beta hydrolase
J8Y16_RS11585	COG2814	Major facilitator Superfamily
J8Y16_RS11605	COG2226	methyltransferase
J8Y16_RS11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS11675	COG1247	-acetyltransferase
J8Y16_RS11705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
J8Y16_RS11715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS11725	COG1278	Cold shock
J8Y16_RS11740	COG0010	Belongs to the arginase family
J8Y16_RS11750	COG0583	DNA-binding transcription factor activity
J8Y16_RS11755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J8Y16_RS11770	COG0583	DNA-binding transcription factor activity
J8Y16_RS11775	COG2258	MOSC domain
J8Y16_RS11790	COG1132	(ABC) transporter
J8Y16_RS11795	COG1132	(ABC) transporter
J8Y16_RS11815	COG1396	sequence-specific DNA binding
J8Y16_RS11850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8Y16_RS11860	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
J8Y16_RS11865	COG1595	DNA-templated transcription, initiation
J8Y16_RS11890	COG1649	PFAM Uncharacterised BCR, COG1649
J8Y16_RS11915	COG2971	BadF BadG BcrA BcrD
J8Y16_RS11925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J8Y16_RS11980	COG1309	transcriptional regulator
J8Y16_RS11995	COG1136	(ABC) transporter
J8Y16_RS11995	COG0577	efflux transmembrane transporter activity
J8Y16_RS12010	COG2226	methyltransferase
J8Y16_RS12045	COG1846	Transcriptional regulator
J8Y16_RS12080	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Y16_RS12090	COG0110	maltose O-acetyltransferase activity
J8Y16_RS12095	COG1686	Belongs to the peptidase S11 family
J8Y16_RS12105	COG0768	penicillin binding
J8Y16_RS12120	COG0768	penicillin binding
J8Y16_RS12125	COG0768	penicillin binding
J8Y16_RS12130	COG2367	Beta-lactamase
J8Y16_RS12135	COG0671	phosphoesterase, PA-phosphatase related
J8Y16_RS12140	COG1609	Transcriptional regulator
J8Y16_RS12145	COG2814	Major facilitator Superfamily
J8Y16_RS12150	COG0673	inositol 2-dehydrogenase activity
J8Y16_RS12180	COG3718	enzyme involved in inositol metabolism
J8Y16_RS12195	COG0737	Belongs to the 5'-nucleotidase family
J8Y16_RS12205	COG0457	Tetratricopeptide repeat
J8Y16_RS12210	COG1476	TRANSCRIPTIONal
J8Y16_RS12225	COG1876	peptidase activity
J8Y16_RS12245	COG1309	transcriptional regulator
J8Y16_RS12250	COG0488	(ABC) transporter
J8Y16_RS12270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS12305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y16_RS12335	COG1960	acyl-CoA dehydrogenase activity
J8Y16_RS12340	COG0439	Biotin carboxylase
J8Y16_RS12345	COG0511	ligase activity, forming carbon-carbon bonds
J8Y16_RS12350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J8Y16_RS12355	COG1024	Enoyl-CoA hydratase
J8Y16_RS12360	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J8Y16_RS12365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Y16_RS12380	COG0572	uridine kinase
J8Y16_RS12390	COG2318	DinB family
J8Y16_RS12395	COG1686	Belongs to the peptidase S11 family
J8Y16_RS12420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J8Y16_RS12440	COG3227	Zinc metalloprotease (Elastase)
J8Y16_RS12455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J8Y16_RS12520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS12545	COG1063	alcohol dehydrogenase
J8Y16_RS12580	COG3386	PFAM SMP-30 Gluconolaconase
J8Y16_RS12590	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
J8Y16_RS12595	COG3773	Cell wall hydrolase
J8Y16_RS12605	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS12610	COG2205	protein histidine kinase activity
J8Y16_RS12620	COG0488	(ABC) transporter
J8Y16_RS12635	COG1136	(ABC) transporter
J8Y16_RS12640	COG0577	efflux transmembrane transporter activity
J8Y16_RS12660	COG0460	homoserine dehydrogenase
J8Y16_RS12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS12675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J8Y16_RS12800	COG2124	cytochrome p450
J8Y16_RS12835	COG0561	phosphatase activity
J8Y16_RS12840	COG5002	protein histidine kinase activity
J8Y16_RS12845	COG0768	penicillin binding
J8Y16_RS12850	COG1819	glycosyl
J8Y16_RS12855	COG1794	racemase activity, acting on amino acids and derivatives
J8Y16_RS12880	COG2205	protein histidine kinase activity
J8Y16_RS12890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y16_RS12895	COG0604	alcohol dehydrogenase
J8Y16_RS12900	COG0768	penicillin binding
J8Y16_RS12910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y16_RS12945	COG0693	protein deglycase activity
J8Y16_RS12970	COG2814	Major facilitator Superfamily
J8Y16_RS12985	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y16_RS13005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS13010	COG0697	spore germination
J8Y16_RS13045	COG2223	nitrite transmembrane transporter activity
J8Y16_RS13050	COG2816	NAD+ diphosphatase activity
J8Y16_RS13055	COG0592	DNA-directed DNA polymerase activity
J8Y16_RS13060	COG1051	belongs to the nudix hydrolase family
J8Y16_RS13085	COG0406	alpha-ribazole phosphatase activity
J8Y16_RS13095	COG3878	Protein conserved in bacteria
J8Y16_RS13115	COG4667	esterase of the alpha-beta hydrolase superfamily
J8Y16_RS13140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J8Y16_RS13155	COG0322	excinuclease ABC activity
J8Y16_RS13195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y16_RS13220	COG1011	Hydrolase
J8Y16_RS13240	COG1523	belongs to the glycosyl hydrolase 13 family
J8Y16_RS13245	COG3227	Zinc metalloprotease (Elastase)
J8Y16_RS13265	COG0201	protein transport
J8Y16_RS13280	COG0697	spore germination
J8Y16_RS13285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS13320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS13335	COG2959	enzyme of heme biosynthesis
J8Y16_RS13370	COG1309	transcriptional regulator
J8Y16_RS13400	COG3284	Transcriptional regulator
J8Y16_RS13415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS13420	COG1349	DNA-binding transcription factor activity
J8Y16_RS13440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Y16_RS13445	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y16_RS13450	COG0022	dehydrogenase e1 component
J8Y16_RS13455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8Y16_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS13470	COG0456	acetyltransferase
J8Y16_RS13470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y16_RS13480	COG0494	nUDIX hydrolase
J8Y16_RS13505	COG4176	ABC-type proline glycine betaine transport system permease component
J8Y16_RS13510	COG0517	IMP dehydrogenase activity
J8Y16_RS13510	COG4175	Glycine betaine
J8Y16_RS13535	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J8Y16_RS13540	COG2153	protein acetylation
J8Y16_RS13545	COG3397	chitin binding
J8Y16_RS13555	COG2205	protein histidine kinase activity
J8Y16_RS13560	COG2226	methyltransferase
J8Y16_RS13565	COG2315	Protein conserved in bacteria
J8Y16_RS13575	COG2333	competence protein COMEC
J8Y16_RS13575	COG0658	competence protein
J8Y16_RS13625	COG3973	AAA domain
J8Y16_RS13655	COG2105	PFAM AIG2 family protein
J8Y16_RS13660	COG0514	ATP-dependent DNA helicase (RecQ)
J8Y16_RS13680	COG4637	Psort location Cytoplasmic, score
J8Y16_RS13700	COG3397	chitin binding
J8Y16_RS13715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J8Y16_RS13720	COG1115	amino acid carrier protein
J8Y16_RS13725	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS13730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J8Y16_RS13740	COG3938	Belongs to the proline racemase family
J8Y16_RS13745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J8Y16_RS13795	COG1078	dGTPase activity
J8Y16_RS13800	COG0586	Pfam SNARE associated Golgi protein
J8Y16_RS13815	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
J8Y16_RS13820	COG0519	Catalyzes the synthesis of GMP from XMP
J8Y16_RS13825	COG4166	transmembrane transport
J8Y16_RS13835	COG4948	Mandelate Racemase Muconate Lactonizing
J8Y16_RS13880	COG2936	dipeptidyl-peptidase activity
J8Y16_RS13885	COG5002	protein histidine kinase activity
J8Y16_RS13890	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS13925	COG1164	Oligoendopeptidase f
J8Y16_RS13930	COG0531	amino acid
J8Y16_RS13935	COG1522	sequence-specific DNA binding
J8Y16_RS13940	COG1307	EDD domain protein, DegV family
J8Y16_RS13960	COG2814	Major facilitator Superfamily
J8Y16_RS13970	COG1664	Polymer-forming cytoskeletal
J8Y16_RS13975	COG0789	Transcriptional regulator
J8Y16_RS13980	COG4533	DNA binding
J8Y16_RS13985	COG0477	Major facilitator Superfamily
J8Y16_RS13985	COG2814	Major facilitator Superfamily
J8Y16_RS14005	COG2261	transglycosylase associated protein
J8Y16_RS14020	COG2226	methyltransferase
J8Y16_RS14050	COG0436	Aminotransferase
J8Y16_RS14055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J8Y16_RS14060	COG5146	pantothenate kinase activity
J8Y16_RS14065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J8Y16_RS14080	COG1131	(ABC) transporter
J8Y16_RS14130	COG0628	permease
J8Y16_RS14140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J8Y16_RS14145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y16_RS14150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y16_RS14180	COG2816	NAD+ diphosphatase activity
J8Y16_RS14200	COG2746	aminoglycoside 3-N-acetyltransferase activity
J8Y16_RS14225	COG0697	spore germination
J8Y16_RS14230	COG2318	DinB family
J8Y16_RS14270	COG0861	Integral membrane protein TerC family
J8Y16_RS14275	COG1368	sulfuric ester hydrolase activity
J8Y16_RS14280	COG0488	(ABC) transporter
J8Y16_RS14290	COG1033	growth of symbiont in host cell
J8Y16_RS14290	COG2409	Drug exporters of the RND superfamily
J8Y16_RS14295	COG1309	transcriptional regulator
J8Y16_RS14310	COG0287	Prephenate dehydrogenase
J8Y16_RS14315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J8Y16_RS14325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
J8Y16_RS14325	COG1605	Chorismate mutase
J8Y16_RS14370	COG2610	gluconate transmembrane transporter activity
J8Y16_RS14375	COG1024	Enoyl-CoA hydratase
J8Y16_RS14385	COG3290	protein histidine kinase activity
J8Y16_RS14385	COG3829	transcription factor binding
J8Y16_RS14400	COG1879	ABC-type sugar transport system periplasmic component
J8Y16_RS14410	COG1172	Belongs to the binding-protein-dependent transport system permease family
J8Y16_RS14420	COG2390	Transcriptional regulator
J8Y16_RS14460	COG2329	Antibiotic biosynthesis monooxygenase
J8Y16_RS14480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS14495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y16_RS14500	COG4187	Peptidase family M20/M25/M40
J8Y16_RS14505	COG1414	Transcriptional regulator
J8Y16_RS14510	COG0833	amino acid
J8Y16_RS14515	COG1690	Belongs to the RtcB family
J8Y16_RS14520	COG3239	Fatty acid desaturase
J8Y16_RS14525	COG1785	Belongs to the alkaline phosphatase family
J8Y16_RS14535	COG3655	Transcriptional regulator
J8Y16_RS14550	COG4377	Putative membrane peptidase family (DUF2324)
J8Y16_RS14560	COG3279	Response regulator of the LytR AlgR family
J8Y16_RS14580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS14585	COG0346	lactoylglutathione lyase activity
J8Y16_RS14610	COG0714	Associated with various cellular activities
J8Y16_RS14635	COG0463	Glycosyl transferase, family 2
J8Y16_RS14650	COG0463	Glycosyl transferase, family 2
J8Y16_RS14660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8Y16_RS14665	COG0753	catalase activity
J8Y16_RS14675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J8Y16_RS14685	COG1280	lysine exporter protein (LysE YggA)
J8Y16_RS14690	COG3403	YqcI/YcgG family
J8Y16_RS14720	COG0714	Associated with various cellular activities
J8Y16_RS14730	COG0778	Nitroreductase
J8Y16_RS14735	COG1846	Transcriptional regulator
J8Y16_RS14770	COG1136	(ABC) transporter
J8Y16_RS14770	COG0577	efflux transmembrane transporter activity
J8Y16_RS14795	COG2207	Transcriptional regulator
J8Y16_RS14800	COG0456	acetyltransferase
J8Y16_RS14820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS14860	COG0730	response to heat
J8Y16_RS14870	COG0833	amino acid
J8Y16_RS14880	COG4335	DNA alkylation repair
J8Y16_RS14910	COG0768	penicillin binding
J8Y16_RS14940	COG1984	allophanate hydrolase subunit 2
J8Y16_RS14945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J8Y16_RS14950	COG1414	Transcriptional regulator
J8Y16_RS14965	COG0860	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS14970	COG0640	Transcriptional regulator
J8Y16_RS14980	COG1960	acyl-CoA dehydrogenase activity
J8Y16_RS15000	COG3314	Sporulation integral membrane protein YlbJ
J8Y16_RS15025	COG0574	Belongs to the PEP-utilizing enzyme family
J8Y16_RS15025	COG3848	Pyruvate phosphate dikinase
J8Y16_RS15030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS15045	COG5577	PFAM Coat F domain
J8Y16_RS15050	COG3403	YqcI/YcgG family
J8Y16_RS15055	COG1280	lysine exporter protein (LysE YggA)
J8Y16_RS15060	COG1113	amino acid transport
J8Y16_RS15090	COG1063	alcohol dehydrogenase
J8Y16_RS15100	COG1027	Aspartate ammonia-lyase
J8Y16_RS15105	COG0252	asparaginase activity
J8Y16_RS15110	COG1396	sequence-specific DNA binding
J8Y16_RS15140	COG5002	protein histidine kinase activity
J8Y16_RS15165	COG2207	Transcriptional regulator
J8Y16_RS15180	COG0322	excinuclease ABC activity
J8Y16_RS15185	COG0531	amino acid
J8Y16_RS15190	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS15205	COG0281	malic enzyme
J8Y16_RS15220	COG0531	amino acid
J8Y16_RS15225	COG0697	spore germination
J8Y16_RS15230	COG0784	Response regulator, receiver
J8Y16_RS15235	COG4191	Histidine kinase
J8Y16_RS15240	COG2066	Belongs to the glutaminase family
J8Y16_RS15245	COG1115	amino acid carrier protein
J8Y16_RS15275	COG0737	Belongs to the 5'-nucleotidase family
J8Y16_RS15280	COG2814	Major facilitator Superfamily
J8Y16_RS15285	COG1846	Transcriptional regulator
J8Y16_RS15290	COG1846	Transcriptional regulator
J8Y16_RS15295	COG2124	cytochrome p450
J8Y16_RS15325	COG2267	carboxylic ester hydrolase activity
J8Y16_RS15330	COG4990	cell redox homeostasis
J8Y16_RS15335	COG2323	membrane
J8Y16_RS15340	COG3443	Belongs to the bacterial solute-binding protein 9 family
J8Y16_RS15340	COG0803	Belongs to the bacterial solute-binding protein 9 family
J8Y16_RS15350	COG2329	Antibiotic biosynthesis monooxygenase
J8Y16_RS15360	COG0598	Magnesium transport protein CorA
J8Y16_RS15420	COG0657	acetylesterase activity
J8Y16_RS15425	COG0288	reversible hydration of carbon dioxide
J8Y16_RS15435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J8Y16_RS15440	COG5609	conserved protein (DUF2294)
J8Y16_RS15455	COG0714	Associated with various cellular activities
J8Y16_RS15465	COG1575	Belongs to the MenA family. Type 1 subfamily
J8Y16_RS15490	COG0803	Belongs to the bacterial solute-binding protein 9 family
J8Y16_RS15495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J8Y16_RS15500	COG1121	(ABC) transporter
J8Y16_RS15515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS15525	COG0798	PFAM Bile acid sodium symporter
J8Y16_RS15530	COG0346	lactoylglutathione lyase activity
J8Y16_RS15535	COG0640	Transcriptional regulator
J8Y16_RS15545	COG0456	acetyltransferase
J8Y16_RS15555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y16_RS15555	COG3320	Male sterility
J8Y16_RS15560	COG1309	transcriptional regulator
J8Y16_RS15565	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS15570	COG1522	sequence-specific DNA binding
J8Y16_RS15585	COG0346	lactoylglutathione lyase activity
J8Y16_RS15625	COG2814	Major facilitator Superfamily
J8Y16_RS15650	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS15655	COG5002	protein histidine kinase activity
J8Y16_RS15655	COG3850	Histidine kinase
J8Y16_RS15685	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J8Y16_RS15710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS15715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J8Y16_RS15740	COG2309	aminopeptidase activity
J8Y16_RS15750	COG0789	Transcriptional regulator
J8Y16_RS15755	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J8Y16_RS15775	COG0577	efflux transmembrane transporter activity
J8Y16_RS15790	COG3850	Histidine kinase
J8Y16_RS15790	COG5002	protein histidine kinase activity
J8Y16_RS15800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS15820	COG1619	proteins homologs of microcin C7 resistance protein MccF
J8Y16_RS15835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J8Y16_RS15855	COG1595	DNA-templated transcription, initiation
J8Y16_RS15870	COG0662	Cupin 2, conserved barrel domain protein
J8Y16_RS15875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS15875	COG2207	Transcriptional regulator
J8Y16_RS15905	COG5632	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS15905	COG3409	Peptidoglycan-binding domain 1 protein
J8Y16_RS15945	COG0477	Major facilitator Superfamily
J8Y16_RS15955	COG1846	Transcriptional regulator
J8Y16_RS15960	COG2814	Major facilitator Superfamily
J8Y16_RS15970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J8Y16_RS15975	COG1131	(ABC) transporter
J8Y16_RS15995	COG2076	Multidrug Resistance protein
J8Y16_RS16000	COG1309	transcriptional regulator
J8Y16_RS16010	COG2814	Major facilitator Superfamily
J8Y16_RS16030	COG2031	fatty acid transporter
J8Y16_RS16040	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y16_RS16075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J8Y16_RS16090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J8Y16_RS16095	COG1288	antiporter activity
J8Y16_RS16100	COG2356	endonuclease I
J8Y16_RS16115	COG3620	sequence-specific DNA binding
J8Y16_RS16125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J8Y16_RS16145	COG1733	regulation of RNA biosynthetic process
J8Y16_RS16150	COG0778	Nitroreductase
J8Y16_RS16170	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS16180	COG1131	(ABC) transporter
J8Y16_RS16205	COG1011	Hydrolase
J8Y16_RS16215	COG2365	Tyrosine phosphatase family
J8Y16_RS16235	COG0346	lactoylglutathione lyase activity
J8Y16_RS16240	COG1940	carbohydrate kinase activity
J8Y16_RS16245	COG0110	maltose O-acetyltransferase activity
J8Y16_RS16260	COG0628	permease
J8Y16_RS16280	COG2226	methyltransferase
J8Y16_RS16290	COG0477	Major facilitator Superfamily
J8Y16_RS16320	COG1253	flavin adenine dinucleotide binding
J8Y16_RS16325	COG0789	Transcriptional regulator
J8Y16_RS16330	COG0697	spore germination
J8Y16_RS16335	COG1357	PFAM Pentapeptide repeats (8 copies)
J8Y16_RS16340	COG3813	Protein conserved in bacteria
J8Y16_RS16345	COG2706	6-phosphogluconolactonase activity
J8Y16_RS16350	COG1070	Carbohydrate kinase
J8Y16_RS16360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J8Y16_RS16365	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J8Y16_RS16375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J8Y16_RS16390	COG3321	synthase
J8Y16_RS16390	COG0604	alcohol dehydrogenase
J8Y16_RS16410	COG0814	amino acid
J8Y16_RS16430	COG1393	Belongs to the ArsC family
J8Y16_RS16440	COG2188	Transcriptional regulator
J8Y16_RS16445	COG0673	inositol 2-dehydrogenase activity
J8Y16_RS16450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J8Y16_RS16455	COG1733	regulation of RNA biosynthetic process
J8Y16_RS16460	COG1733	regulation of RNA biosynthetic process
J8Y16_RS16475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS16495	COG0384	phenazine biosynthesis protein PhzF
J8Y16_RS16505	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS16520	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS16525	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y16_RS16530	COG1733	regulation of RNA biosynthetic process
J8Y16_RS16550	COG1191	sigma factor activity
J8Y16_RS16560	COG1266	CAAX protease self-immunity
J8Y16_RS16570	COG1309	transcriptional regulator
J8Y16_RS16635	COG1151	hydroxylamine reductase activity
J8Y16_RS16645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS16650	COG3757	hydrolase, family 25
J8Y16_RS16650	COG3409	Peptidoglycan-binding domain 1 protein
J8Y16_RS16685	COG2072	flavoprotein involved in K transport
J8Y16_RS16730	COG1695	Transcriptional regulator
J8Y16_RS16735	COG0604	alcohol dehydrogenase
J8Y16_RS16740	COG1113	amino acid transport
J8Y16_RS16745	COG2814	Major facilitator Superfamily
J8Y16_RS16775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J8Y16_RS16780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Y16_RS16795	COG3739	integral membrane protein
J8Y16_RS16800	COG0384	phenazine biosynthesis protein PhzF
J8Y16_RS16820	COG0583	DNA-binding transcription factor activity
J8Y16_RS16840	COG1193	negative regulation of DNA recombination
J8Y16_RS16855	COG2162	N-hydroxyarylamine O-acetyltransferase activity
J8Y16_RS16860	COG1164	Oligoendopeptidase f
J8Y16_RS16865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J8Y16_RS16895	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y16_RS16920	COG0640	Transcriptional regulator
J8Y16_RS16925	COG0604	alcohol dehydrogenase
J8Y16_RS16935	COG0457	Tetratricopeptide repeat
J8Y16_RS16945	COG0385	Bile acid
J8Y16_RS16950	COG0277	FAD linked oxidase domain protein
J8Y16_RS16985	COG1216	Glycosyl transferase, family 2
J8Y16_RS16990	COG1024	Enoyl-CoA hydratase
J8Y16_RS17000	COG1285	pathogenesis
J8Y16_RS17015	COG2514	catechol 2,3-dioxygenase activity
J8Y16_RS17020	COG2720	vancomycin resistance protein
J8Y16_RS17055	COG0716	FMN binding
J8Y16_RS17085	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS17095	COG0165	Argininosuccinate lyase
J8Y16_RS17110	COG4145	pantothenate transmembrane transporter activity
J8Y16_RS17120	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS17125	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS17135	COG1657	PFAM Prenyltransferase squalene oxidase
J8Y16_RS17140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
J8Y16_RS17145	COG2962	Rard protein
J8Y16_RS17150	COG3326	Membrane
J8Y16_RS17165	COG0489	protein tyrosine kinase activity
J8Y16_RS17175	COG0314	molybdopterin synthase activity
J8Y16_RS17180	COG0303	'Molybdopterin
J8Y16_RS17185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y16_RS17190	COG2116	formate transmembrane transporter activity
J8Y16_RS17200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J8Y16_RS17205	COG5609	conserved protein (DUF2294)
J8Y16_RS17210	COG2427	Protein of unknown function (DUF1641)
J8Y16_RS17215	COG3383	formate dehydrogenase (NAD+) activity
J8Y16_RS17220	COG0697	spore germination
J8Y16_RS17260	COG2226	methyltransferase
J8Y16_RS17265	COG4166	transmembrane transport
J8Y16_RS17270	COG4166	transmembrane transport
J8Y16_RS17275	COG4166	transmembrane transport
J8Y16_RS17280	COG1301	dicarboxylic acid transport
J8Y16_RS17285	COG1316	TRANSCRIPTIONal
J8Y16_RS17295	COG1595	DNA-templated transcription, initiation
J8Y16_RS17315	COG1131	(ABC) transporter
J8Y16_RS17325	COG0673	inositol 2-dehydrogenase activity
J8Y16_RS17330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J8Y16_RS17335	COG0187	DNA topoisomerase II activity
J8Y16_RS17340	COG1832	CoA-binding protein
J8Y16_RS17345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Y16_RS17350	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS17370	COG4841	protein insertion into membrane
J8Y16_RS17375	COG0824	Thioesterase
J8Y16_RS17405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y16_RS17415	COG1132	(ABC) transporter
J8Y16_RS17420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J8Y16_RS17460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J8Y16_RS17475	COG0183	Belongs to the thiolase family
J8Y16_RS17480	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS17485	COG1268	BioY protein
J8Y16_RS17490	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS17505	COG1396	sequence-specific DNA binding
J8Y16_RS17555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS17565	COG5002	protein histidine kinase activity
J8Y16_RS17570	COG0400	carboxylic ester hydrolase activity
J8Y16_RS17575	COG0346	lactoylglutathione lyase activity
J8Y16_RS17580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J8Y16_RS17585	COG0069	glutamate synthase activity
J8Y16_RS17590	COG1902	pentaerythritol trinitrate reductase activity
J8Y16_RS17595	COG1329	Transcriptional regulator
J8Y16_RS17600	COG0010	Belongs to the arginase family
J8Y16_RS17625	COG2226	methyltransferase
J8Y16_RS17660	COG4846	Membrane protein involved in cytochrome C biogenesis
J8Y16_RS17665	COG0785	Cytochrome C biogenesis protein
J8Y16_RS17675	COG1473	amidohydrolase
J8Y16_RS17685	COG1131	(ABC) transporter
J8Y16_RS17695	COG0583	DNA-binding transcription factor activity
J8Y16_RS17705	COG1346	cytolysis
J8Y16_RS17720	COG0730	response to heat
J8Y16_RS17730	COG3409	Peptidoglycan-binding domain 1 protein
J8Y16_RS17730	COG5632	N-Acetylmuramoyl-L-alanine amidase
J8Y16_RS17760	COG1132	(ABC) transporter
J8Y16_RS17765	COG1132	(ABC) transporter
J8Y16_RS17790	COG3639	organic phosphonate transmembrane transporter activity
J8Y16_RS17805	COG0737	Belongs to the 5'-nucleotidase family
J8Y16_RS17815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J8Y16_RS17835	COG1695	Transcriptional regulator
J8Y16_RS17840	COG0174	glutamine synthetase
J8Y16_RS17845	COG0789	Transcriptional regulator
J8Y16_RS17850	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
J8Y16_RS17860	COG2860	membrane
J8Y16_RS17865	COG0464	growth
J8Y16_RS17895	COG1388	LysM domain
J8Y16_RS17895	COG3584	3D domain protein
J8Y16_RS17900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Y16_RS17900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J8Y16_RS17900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Y16_RS17905	COG1105	Belongs to the carbohydrate kinase PfkB family
J8Y16_RS17910	COG1349	DNA-binding transcription factor activity
J8Y16_RS17915	COG1979	alcohol dehydrogenase
J8Y16_RS17920	COG2322	membrane
J8Y16_RS17930	COG1113	amino acid transport
J8Y16_RS17940	COG1408	metallophosphoesterase
J8Y16_RS17945	COG2116	formate transmembrane transporter activity
J8Y16_RS17960	COG2217	Heavy metal translocating P-type atpase
J8Y16_RS17965	COG2608	mercury ion transmembrane transporter activity
J8Y16_RS17970	COG1937	Protein conserved in bacteria
J8Y16_RS17980	COG2819	hydrolase of the alpha beta superfamily
J8Y16_RS17985	COG1120	ATPase activity
J8Y16_RS17990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS18000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS18005	COG0708	Exodeoxyribonuclease III
J8Y16_RS18010	COG2169	Transcriptional regulator
J8Y16_RS18015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J8Y16_RS18020	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
J8Y16_RS18030	COG2364	Membrane
J8Y16_RS18045	COG2267	carboxylic ester hydrolase activity
J8Y16_RS18050	COG0346	lactoylglutathione lyase activity
J8Y16_RS18055	COG3300	MHYT domain
J8Y16_RS18055	COG5001	Diguanylate cyclase
J8Y16_RS18070	COG1346	cytolysis
J8Y16_RS18075	COG1380	Effector of murein hydrolase LrgA
J8Y16_RS18080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J8Y16_RS18085	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y16_RS18085	COG0596	Alpha beta hydrolase
J8Y16_RS18090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J8Y16_RS18110	COG1404	Belongs to the peptidase S8 family
J8Y16_RS18115	COG3773	Cell wall hydrolase
J8Y16_RS18120	COG0562	UDP-galactopyranose mutase
J8Y16_RS18125	COG1368	sulfuric ester hydrolase activity
J8Y16_RS18130	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J8Y16_RS18140	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
J8Y16_RS18165	COG1131	(ABC) transporter
J8Y16_RS18185	COG4550	Control of competence regulator ComK, YlbF/YmcA
J8Y16_RS18195	COG1013	pyruvate-flavodoxin oxidoreductase activity
J8Y16_RS18200	COG0674	pyruvate-flavodoxin oxidoreductase activity
J8Y16_RS18200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J8Y16_RS18210	COG2359	stage V sporulation protein S
J8Y16_RS18215	COG1692	metallophosphoesterase
J8Y16_RS18240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J8Y16_RS18245	COG1426	Protein conserved in bacteria
J8Y16_RS18260	COG0300	oxidoreductase activity
J8Y16_RS18265	COG0612	Peptidase, M16
J8Y16_RS18270	COG0612	Peptidase, M16
J8Y16_RS18275	COG1079	Belongs to the binding-protein-dependent transport system permease family
J8Y16_RS18280	COG4603	Belongs to the binding-protein-dependent transport system permease family
J8Y16_RS18285	COG3845	ABC transporter
J8Y16_RS18290	COG1744	ABC transporter substrate-binding protein PnrA-like
J8Y16_RS18295	COG2188	Transcriptional regulator
J8Y16_RS18300	COG1674	ftsk spoiiie
J8Y16_RS18310	COG0740	serine-type endopeptidase activity
J8Y16_RS18315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J8Y16_RS18325	COG0527	aspartate kinase activity
J8Y16_RS18330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J8Y16_RS18335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J8Y16_RS18340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8Y16_RS18345	COG1873	PFAM PRC-barrel domain
J8Y16_RS18350	COG0612	Peptidase, M16
J8Y16_RS18355	COG0726	polysaccharide deacetylase
J8Y16_RS18370	COG0196	riboflavin kinase activity
J8Y16_RS18385	COG1550	Protein conserved in bacteria
J8Y16_RS18395	COG1358	cellular component organization or biogenesis
J8Y16_RS18400	COG2740	Nucleic-acid-binding protein implicated in transcription termination
J8Y16_RS18405	COG0195	Participates in both transcription termination and antitermination
J8Y16_RS18425	COG0750	zinc metalloprotease
J8Y16_RS18435	COG4589	Belongs to the CDS family
J8Y16_RS18450	COG0528	UMP kinase activity
J8Y16_RS18480	COG4974	Belongs to the 'phage' integrase family
J8Y16_RS18490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J8Y16_RS18495	COG0758	DNA mediated transformation
J8Y16_RS18500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J8Y16_RS18540	COG1837	Belongs to the UPF0109 family
J8Y16_RS18550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J8Y16_RS18560	COG0552	protein localization to endoplasmic reticulum
J8Y16_RS18565	COG1196	nuclear chromosome segregation
J8Y16_RS18575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J8Y16_RS18580	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS18585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J8Y16_RS18600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J8Y16_RS18605	COG1461	Dihydroxyacetone kinase
J8Y16_RS18610	COG1302	Protein conserved in bacteria
J8Y16_RS18625	COG1564	THIamine pyrophosphokinase
J8Y16_RS18630	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J8Y16_RS18640	COG2815	serine threonine protein kinase
J8Y16_RS18640	COG0515	serine threonine protein kinase
J8Y16_RS18645	COG0631	protein serine/threonine phosphatase activity
J8Y16_RS18655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J8Y16_RS18655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J8Y16_RS18665	COG0242	peptide deformylase activity
J8Y16_RS18670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J8Y16_RS18675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J8Y16_RS18695	COG1561	YicC-like family, N-terminal region
J8Y16_RS18700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J8Y16_RS18715	COG0006	proline dipeptidase activity
J8Y16_RS18730	COG3069	C4-dicarboxylate transmembrane transporter activity
J8Y16_RS18805	COG0564	pseudouridine synthase activity
J8Y16_RS18825	COG3599	regulation of cell shape
J8Y16_RS18830	COG2302	S4 RNA-binding domain
J8Y16_RS18835	COG0762	integral membrane protein
J8Y16_RS18845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J8Y16_RS18850	COG1496	oxidoreductase activity
J8Y16_RS18855	COG1873	PFAM PRC-barrel domain
J8Y16_RS18865	COG1191	sigma factor activity
J8Y16_RS18870	COG1191	sigma factor activity
J8Y16_RS18880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J8Y16_RS18885	COG0849	cell division
J8Y16_RS18890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J8Y16_RS18895	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J8Y16_RS18905	COG0772	Belongs to the SEDS family
J8Y16_RS18920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J8Y16_RS18925	COG0768	penicillin binding
J8Y16_RS18930	COG0768	penicillin binding
J8Y16_RS18935	COG4839	cell division protein FtsL
J8Y16_RS18950	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J8Y16_RS18965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J8Y16_RS18970	COG1399	metal-binding, possibly nucleic acid-binding protein
J8Y16_RS18980	COG3480	Lon protease (S16) C-terminal proteolytic domain
J8Y16_RS18985	COG1752	Esterase of the alpha-beta hydrolase superfamily
J8Y16_RS18990	COG3314	Sporulation integral membrane protein YlbJ
J8Y16_RS19000	COG0742	ribosomal rna small subunit methyltransferase
J8Y16_RS19015	COG3679	Belongs to the UPF0342 family
J8Y16_RS19020	COG0406	alpha-ribazole phosphatase activity
J8Y16_RS19035	COG2340	Cysteine-rich secretory protein family
J8Y16_RS19050	COG3336	cytochrome c oxidase
J8Y16_RS19085	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J8Y16_RS19090	COG0772	Belongs to the SEDS family
J8Y16_RS19100	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J8Y16_RS19105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J8Y16_RS19115	COG4896	Protein conserved in bacteria
J8Y16_RS19135	COG1217	gtp-binding protein TYPA
J8Y16_RS19145	COG0483	inositol monophosphate 1-phosphatase activity
J8Y16_RS19165	COG1982	Orn Lys Arg decarboxylase major
J8Y16_RS19215	COG0022	dehydrogenase e1 component
J8Y16_RS19220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8Y16_RS19230	COG0242	peptide deformylase activity
J8Y16_RS19235	COG0561	phosphatase activity
J8Y16_RS19245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J8Y16_RS19250	COG0569	domain protein
J8Y16_RS19270	COG0583	DNA-binding transcription factor activity
J8Y16_RS19275	COG0517	IMP dehydrogenase activity
J8Y16_RS19285	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
J8Y16_RS19295	COG4703	Protein of unknown function (DUF1797)
J8Y16_RS19310	COG2200	EAL domain
J8Y16_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS19320	COG1408	metallophosphoesterase
J8Y16_RS19330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J8Y16_RS19370	COG2814	Major facilitator Superfamily
J8Y16_RS19390	COG3209	COG3209 Rhs family protein
J8Y16_RS19400	COG2205	protein histidine kinase activity
J8Y16_RS19410	COG0436	Aminotransferase
J8Y16_RS19415	COG1609	Transcriptional regulator
J8Y16_RS19420	COG3833	ABC-type maltose transport systems, permease component
J8Y16_RS19425	COG1175	transmembrane transport
J8Y16_RS19430	COG2182	Extracellular solute-binding protein
J8Y16_RS19440	COG0366	Alpha amylase catalytic
J8Y16_RS19445	COG3842	ATPase activity
J8Y16_RS19490	COG0183	Belongs to the thiolase family
J8Y16_RS19525	COG1695	Transcriptional regulator
J8Y16_RS19530	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS19550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J8Y16_RS19555	COG0436	Aminotransferase
J8Y16_RS19590	COG2084	Dehydrogenase
J8Y16_RS19595	COG2199	diguanylate cyclase activity
J8Y16_RS19600	COG0778	Nitroreductase
J8Y16_RS19625	COG1263	PTS System
J8Y16_RS19625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J8Y16_RS19625	COG2190	(PTS) system
J8Y16_RS19630	COG3711	transcriptional antiterminator
J8Y16_RS19640	COG2188	Transcriptional regulator
J8Y16_RS19650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J8Y16_RS19675	COG1547	Domain of unknown function (DUF309)
J8Y16_RS19680	COG0456	acetyltransferase
J8Y16_RS19685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J8Y16_RS19690	COG4086	secreted protein
J8Y16_RS19695	COG0561	phosphatase activity
J8Y16_RS19700	COG0697	spore germination
J8Y16_RS19715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y16_RS19740	COG0733	neurotransmitter:sodium symporter activity
J8Y16_RS19760	COG1686	Belongs to the peptidase S11 family
J8Y16_RS19765	COG1725	Transcriptional regulator
J8Y16_RS19770	COG1131	(ABC) transporter
J8Y16_RS19790	COG1846	Transcriptional regulator
J8Y16_RS19805	COG0598	Magnesium transport protein CorA
J8Y16_RS19830	COG4974	Belongs to the 'phage' integrase family
J8Y16_RS19840	COG0735	belongs to the Fur family
J8Y16_RS19845	COG1300	Membrane
J8Y16_RS19865	COG0667	Aldo Keto reductase
J8Y16_RS19870	COG0656	L-ascorbic acid biosynthetic process
J8Y16_RS19875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J8Y16_RS19875	COG0456	acetyltransferase
J8Y16_RS19885	COG0737	Belongs to the 5'-nucleotidase family
J8Y16_RS19885	COG4085	toxin activity
J8Y16_RS19885	COG1525	nuclease
J8Y16_RS19895	COG0596	Alpha beta hydrolase
J8Y16_RS19900	COG2056	Na+-H+ antiporter family
J8Y16_RS19905	COG1609	Transcriptional regulator
J8Y16_RS19910	COG0456	acetyltransferase
J8Y16_RS19915	COG1073	alpha beta
J8Y16_RS19930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Y16_RS19930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J8Y16_RS19935	COG0307	riboflavin synthase, alpha
J8Y16_RS19960	COG4106	trans-aconitate 2-methyltransferase activity
J8Y16_RS19965	COG1073	alpha beta
J8Y16_RS19965	COG2226	methyltransferase
J8Y16_RS19980	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J8Y16_RS19990	COG1757	Na H antiporter
J8Y16_RS19995	COG0737	Belongs to the 5'-nucleotidase family
J8Y16_RS20005	COG1522	sequence-specific DNA binding
J8Y16_RS20025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J8Y16_RS20035	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J8Y16_RS20050	COG0300	oxidoreductase activity
J8Y16_RS20055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS20060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y16_RS20065	COG1760	l-serine dehydratase
J8Y16_RS20070	COG1760	l-serine dehydratase
J8Y16_RS20090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J8Y16_RS20100	COG2195	Cleaves the N-terminal amino acid of tripeptides
J8Y16_RS20105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS20120	COG1376	ErfK ybiS ycfS ynhG family protein
J8Y16_RS20125	COG4129	membrane
J8Y16_RS20130	COG1126	abc transporter atp-binding protein
J8Y16_RS20135	COG0765	amino acid transport
J8Y16_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J8Y16_RS20155	COG2816	NAD+ diphosphatase activity
J8Y16_RS20160	COG0772	Belongs to the SEDS family
J8Y16_RS20165	COG0508	dehydrogenase complex catalyzes the overall conversion of
J8Y16_RS20170	COG0022	dehydrogenase e1 component
J8Y16_RS20175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J8Y16_RS20180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J8Y16_RS20195	COG0280	phosphate acetyltransferase
J8Y16_RS20200	COG3290	protein histidine kinase activity
J8Y16_RS20200	COG3829	transcription factor binding
J8Y16_RS20210	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y16_RS20215	COG3093	addiction module antidote protein HigA
J8Y16_RS20225	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS20230	COG0750	zinc metalloprotease
J8Y16_RS20235	COG0497	DNA recombination
J8Y16_RS20245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J8Y16_RS20255	COG0142	geranyltranstransferase activity
J8Y16_RS20280	COG1302	Protein conserved in bacteria
J8Y16_RS20285	COG0439	Biotin carboxylase
J8Y16_RS20290	COG0511	ligase activity, forming carbon-carbon bonds
J8Y16_RS20335	COG3854	ATPases associated with a variety of cellular activities
J8Y16_RS20360	COG0006	proline dipeptidase activity
J8Y16_RS20375	COG3872	metal-dependent enzyme
J8Y16_RS20385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J8Y16_RS20400	COG1695	Transcriptional regulator
J8Y16_RS20415	COG0095	Lipoate-protein ligase
J8Y16_RS20420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y16_RS20425	COG1609	Transcriptional regulator
J8Y16_RS20435	COG2076	Multidrug Resistance protein
J8Y16_RS20440	COG2076	Multidrug Resistance protein
J8Y16_RS20475	COG1131	(ABC) transporter
J8Y16_RS20480	COG1725	Transcriptional regulator
J8Y16_RS20510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J8Y16_RS20565	COG4970	Tfp pilus assembly protein FimT
J8Y16_RS20575	COG1459	type II secretion system
J8Y16_RS20580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J8Y16_RS20625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J8Y16_RS20630	COG0646	methionine synthase
J8Y16_RS20630	COG1410	methionine synthase
J8Y16_RS20635	COG0646	methionine synthase
J8Y16_RS20635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J8Y16_RS20640	COG0626	cystathionine gamma-synthase activity
J8Y16_RS20645	COG0626	cystathionine gamma-synthase activity
J8Y16_RS20665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS20675	COG1940	carbohydrate kinase activity
J8Y16_RS20680	COG4483	Protein conserved in bacteria
J8Y16_RS20685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J8Y16_RS20690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J8Y16_RS20695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J8Y16_RS20700	COG0704	Plays a role in the regulation of phosphate uptake
J8Y16_RS20710	COG0581	inorganic phosphate transmembrane transporter activity
J8Y16_RS20715	COG0573	inorganic phosphate transmembrane transporter activity
J8Y16_RS20720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J8Y16_RS20725	COG0768	penicillin binding
J8Y16_RS20730	COG0477	Major facilitator Superfamily
J8Y16_RS20735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8Y16_RS20760	COG0735	belongs to the Fur family
J8Y16_RS20765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J8Y16_RS20770	COG1121	(ABC) transporter
J8Y16_RS20775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS20805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J8Y16_RS20810	COG2384	SAM-dependent methyltransferase
J8Y16_RS20815	COG2010	Cytochrome c
J8Y16_RS20820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J8Y16_RS20825	COG0358	DNA primase activity
J8Y16_RS20835	COG0517	IMP dehydrogenase activity
J8Y16_RS20850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J8Y16_RS20855	COG0295	cytidine deaminase activity
J8Y16_RS20860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J8Y16_RS20870	COG1480	7TM receptor with intracellular HD hydrolase
J8Y16_RS20875	COG1702	phosphate starvation-inducible protein PhoH
J8Y16_RS20890	COG1610	YqeY-like protein
J8Y16_RS20895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J8Y16_RS20900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J8Y16_RS20905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J8Y16_RS20935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J8Y16_RS20940	COG1733	regulation of RNA biosynthetic process
J8Y16_RS20965	COG1466	dna polymerase III delta subunit
J8Y16_RS20975	COG0658	competence protein
J8Y16_RS20975	COG2333	competence protein COMEC
J8Y16_RS20980	COG2131	deaminase
J8Y16_RS20985	COG1555	photosystem II stabilization
J8Y16_RS20985	COG1596	polysaccharide export
J8Y16_RS20990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J8Y16_RS20995	COG2226	methyltransferase
J8Y16_RS21000	COG0799	negative regulation of ribosome biogenesis
J8Y16_RS21005	COG1713	HD superfamily hydrolase involved in NAD metabolism
J8Y16_RS21015	COG1534	Rna-binding protein
J8Y16_RS21025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
J8Y16_RS21030	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
J8Y16_RS21055	COG1595	DNA-templated transcription, initiation
J8Y16_RS21065	COG0778	Nitroreductase
J8Y16_RS21070	COG2357	RelA SpoT domain protein
J8Y16_RS21080	COG1785	Belongs to the alkaline phosphatase family
J8Y16_RS21090	COG2267	carboxylic ester hydrolase activity
J8Y16_RS21125	COG1404	Belongs to the peptidase S8 family
J8Y16_RS21130	COG3186	Phenylalanine-4-hydroxylase
J8Y16_RS21140	COG2514	catechol 2,3-dioxygenase activity
J8Y16_RS21145	COG2259	Doxx family
J8Y16_RS21185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS21195	COG1454	alcohol dehydrogenase
J8Y16_RS21195	COG1012	belongs to the aldehyde dehydrogenase family
J8Y16_RS21200	COG0626	cystathionine gamma-synthase activity
J8Y16_RS21205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J8Y16_RS21230	COG0768	penicillin binding
J8Y16_RS21245	COG0826	peptidase U32
J8Y16_RS21250	COG0826	peptidase U32
J8Y16_RS21255	COG4122	O-methyltransferase activity
J8Y16_RS21260	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J8Y16_RS21290	COG0628	permease
J8Y16_RS21310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J8Y16_RS21325	COG1104	cysteine desulfurase activity
J8Y16_RS21330	COG1959	2 iron, 2 sulfur cluster binding
J8Y16_RS21335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J8Y16_RS21345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J8Y16_RS21370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J8Y16_RS21380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
J8Y16_RS21380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J8Y16_RS21385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J8Y16_RS21390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Y16_RS21390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J8Y16_RS21400	COG2244	polysaccharide biosynthetic process
J8Y16_RS21405	COG2323	membrane
J8Y16_RS21415	COG1862	Preprotein translocase
J8Y16_RS21445	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J8Y16_RS21455	COG0697	spore germination
J8Y16_RS21460	COG0640	Transcriptional regulator
J8Y16_RS21485	COG0157	Belongs to the NadC ModD family
J8Y16_RS21490	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J8Y16_RS21495	COG1104	cysteine desulfurase activity
J8Y16_RS21500	COG1827	regulation of RNA biosynthetic process
J8Y16_RS21505	COG2258	MOSC domain
J8Y16_RS21510	COG0077	Prephenate dehydratase
J8Y16_RS21515	COG0577	efflux transmembrane transporter activity
J8Y16_RS21520	COG0577	efflux transmembrane transporter activity
J8Y16_RS21525	COG1136	(ABC) transporter
J8Y16_RS21530	COG5002	protein histidine kinase activity
J8Y16_RS21535	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS21545	COG3290	protein histidine kinase activity
J8Y16_RS21555	COG2868	ribosomal protein
J8Y16_RS21565	COG1530	ribonuclease E activity
J8Y16_RS21570	COG1994	Peptidase M50
J8Y16_RS21575	COG0739	heme binding
J8Y16_RS21580	COG2894	cell division
J8Y16_RS21600	COG1077	Cell shape determining protein MreB Mrl
J8Y16_RS21665	COG1309	transcriptional regulator
J8Y16_RS21670	COG1683	Conserved Protein
J8Y16_RS21720	COG0285	dihydrofolate synthase activity
J8Y16_RS21725	COG0525	valine-tRNA ligase activity
J8Y16_RS21735	COG1388	LysM domain
J8Y16_RS21745	COG0113	porphobilinogen synthase activity
J8Y16_RS21750	COG1587	Uroporphyrinogen-III synthase
J8Y16_RS21760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J8Y16_RS21770	COG1846	Transcriptional regulator
J8Y16_RS21775	COG1764	response to oxidative stress
J8Y16_RS21790	COG0470	DNA polymerase III
J8Y16_RS21790	COG1067	ATP-dependent peptidase activity
J8Y16_RS21835	COG0622	Phosphoesterase
J8Y16_RS21850	COG5401	PFAM Sporulation and spore germination
J8Y16_RS21870	COG1309	transcriptional regulator
J8Y16_RS21885	COG2197	response regulator
J8Y16_RS21890	COG2233	PERMEase
J8Y16_RS21895	COG0402	S-adenosylhomocysteine deaminase activity
J8Y16_RS21900	COG1983	PspC domain protein
J8Y16_RS21905	COG1396	sequence-specific DNA binding
J8Y16_RS21910	COG0697	spore germination
J8Y16_RS21920	COG1959	2 iron, 2 sulfur cluster binding
J8Y16_RS21925	COG1668	transmembrane transport
J8Y16_RS21930	COG4152	abc transporter atp-binding protein
J8Y16_RS21935	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
J8Y16_RS21940	COG1360	Flagellar Motor Protein
J8Y16_RS21945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J8Y16_RS21950	COG1876	peptidase activity
J8Y16_RS21955	COG0824	Thioesterase
J8Y16_RS21960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J8Y16_RS21965	COG1053	succinate dehydrogenase
J8Y16_RS21970	COG2009	succinate dehydrogenase
J8Y16_RS21975	COG1719	4-vinyl reductase, 4VR
J8Y16_RS21985	COG3118	belongs to the thioredoxin family
J8Y16_RS21990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J8Y16_RS21995	COG2086	electron transfer activity
J8Y16_RS22000	COG1024	Enoyl-CoA hydratase
J8Y16_RS22005	COG1309	transcriptional regulator
J8Y16_RS22010	COG0318	PFAM AMP-dependent synthetase and ligase
J8Y16_RS22030	COG2318	DinB family
J8Y16_RS22050	COG1131	(ABC) transporter
J8Y16_RS22055	COG2205	protein histidine kinase activity
J8Y16_RS22060	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS22070	COG4895	conserved protein (DUF2196)
J8Y16_RS22075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J8Y16_RS22090	COG4509	Sortase family
J8Y16_RS22095	COG1120	ATPase activity
J8Y16_RS22110	COG5386	Cell surface protein
J8Y16_RS22115	COG5386	Cell surface protein
J8Y16_RS22120	COG1114	Component of the transport system for branched-chain amino acids
J8Y16_RS22125	COG1187	pseudouridine synthase activity
J8Y16_RS22135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
J8Y16_RS22135	COG1796	DNA polymerase
J8Y16_RS22140	COG1286	toxin biosynthetic process
J8Y16_RS22185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J8Y16_RS22195	COG1418	mRNA catabolic process
J8Y16_RS22220	COG2814	Major facilitator Superfamily
J8Y16_RS22225	COG1566	PFAM secretion protein HlyD family protein
J8Y16_RS22230	COG1309	transcriptional regulator
J8Y16_RS22235	COG1363	Peptidase, m42
J8Y16_RS22260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J8Y16_RS22270	COG1484	DNA-dependent DNA replication
J8Y16_RS22275	COG3611	Membrane attachment protein
J8Y16_RS22285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J8Y16_RS22290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8Y16_RS22295	COG0237	dephospho-CoA kinase activity
J8Y16_RS22300	COG1971	Probably functions as a manganese efflux pump
J8Y16_RS22310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y16_RS22310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J8Y16_RS22315	COG5002	protein histidine kinase activity
J8Y16_RS22320	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS22335	COG0538	isocitrate dehydrogenase activity
J8Y16_RS22340	COG0372	Belongs to the citrate synthase family
J8Y16_RS22350	COG0628	permease
J8Y16_RS22355	COG3030	protein affecting phage T7 exclusion by the F plasmid
J8Y16_RS22380	COG1725	Transcriptional regulator
J8Y16_RS22385	COG0281	malic enzyme
J8Y16_RS22390	COG0587	DNA-directed DNA polymerase activity
J8Y16_RS22405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J8Y16_RS22425	COG4109	DRTGG domain
J8Y16_RS22440	COG0006	proline dipeptidase activity
J8Y16_RS22470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS22475	COG0662	Cupin 2, conserved barrel domain protein
J8Y16_RS22490	COG1028	Short-chain dehydrogenase reductase Sdr
J8Y16_RS22495	COG0589	response to stress
J8Y16_RS22535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS22550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J8Y16_RS22555	COG0827	DNA restriction-modification system
J8Y16_RS22560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J8Y16_RS22565	COG3874	Sporulation protein YtfJ
J8Y16_RS22580	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J8Y16_RS22590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Y16_RS22605	COG1104	cysteine desulfurase activity
J8Y16_RS22615	COG0583	DNA-binding transcription factor activity
J8Y16_RS22620	COG0697	spore germination
J8Y16_RS22625	COG1309	transcriptional regulator
J8Y16_RS22630	COG1956	GAF domain-containing protein
J8Y16_RS22635	COG0626	cystathionine gamma-synthase activity
J8Y16_RS22665	COG1595	DNA-templated transcription, initiation
J8Y16_RS22675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J8Y16_RS22680	COG0454	-acetyltransferase
J8Y16_RS22685	COG0517	IMP dehydrogenase activity
J8Y16_RS22690	COG0123	including yeast histone deacetylase and acetoin utilization protein
J8Y16_RS22705	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS22710	COG5002	protein histidine kinase activity
J8Y16_RS22715	COG0666	response to abiotic stimulus
J8Y16_RS22750	COG1609	Transcriptional regulator
J8Y16_RS22760	COG4851	CamS sex pheromone cAM373 precursor
J8Y16_RS22765	COG3118	belongs to the thioredoxin family
J8Y16_RS22775	COG2309	aminopeptidase activity
J8Y16_RS22795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS22800	COG1695	Transcriptional regulator
J8Y16_RS22820	COG1674	ftsk spoiiie
J8Y16_RS22830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J8Y16_RS22840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y16_RS22845	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
J8Y16_RS22850	COG1363	Peptidase, m42
J8Y16_RS22860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS22875	COG0510	thiamine kinase activity
J8Y16_RS22880	COG1523	belongs to the glycosyl hydrolase 13 family
J8Y16_RS22890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J8Y16_RS22895	COG1349	DNA-binding transcription factor activity
J8Y16_RS22900	COG1187	pseudouridine synthase activity
J8Y16_RS22905	COG2244	polysaccharide biosynthetic process
J8Y16_RS22910	COG2081	HI0933 family
J8Y16_RS22915	COG2814	Major facilitator Superfamily
J8Y16_RS22925	COG3832	glyoxalase III activity
J8Y16_RS22955	COG1329	Transcriptional regulator
J8Y16_RS22980	COG0314	molybdopterin synthase activity
J8Y16_RS22995	COG1763	Mo-molybdopterin cofactor biosynthetic process
J8Y16_RS23000	COG0303	'Molybdopterin
J8Y16_RS23010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
J8Y16_RS23015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J8Y16_RS23035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J8Y16_RS23045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J8Y16_RS23090	COG2814	Major facilitator Superfamily
J8Y16_RS23095	COG0475	glutathione-regulated potassium exporter activity
J8Y16_RS23100	COG0490	domain, Protein
J8Y16_RS23105	COG0582	viral genome integration into host DNA
J8Y16_RS23115	COG1136	(ABC) transporter
J8Y16_RS23135	COG1242	4 iron, 4 sulfur cluster binding
J8Y16_RS23140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
J8Y16_RS23155	COG1794	racemase activity, acting on amino acids and derivatives
J8Y16_RS23165	COG5504	Zn-dependent protease
J8Y16_RS23190	COG2267	carboxylic ester hydrolase activity
J8Y16_RS23195	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J8Y16_RS23200	COG0671	phosphoesterase, PA-phosphatase related
J8Y16_RS23205	COG0438	transferase activity, transferring glycosyl groups
J8Y16_RS23215	COG0521	Mo-molybdopterin cofactor biosynthetic process
J8Y16_RS23275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J8Y16_RS23280	COG0546	phosphoglycolate phosphatase activity
J8Y16_RS23285	COG1349	DNA-binding transcription factor activity
J8Y16_RS23295	COG5002	protein histidine kinase activity
J8Y16_RS23300	COG4191	Histidine kinase
J8Y16_RS23305	COG2267	carboxylic ester hydrolase activity
J8Y16_RS23310	COG1368	sulfuric ester hydrolase activity
J8Y16_RS23325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J8Y16_RS23330	COG1116	anion transmembrane transporter activity
J8Y16_RS23335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J8Y16_RS23350	COG0546	phosphoglycolate phosphatase activity
J8Y16_RS23360	COG0494	nUDIX hydrolase
J8Y16_RS23395	COG0288	reversible hydration of carbon dioxide
J8Y16_RS23400	COG1271	oxidase subunit
J8Y16_RS23405	COG1294	oxidase, subunit
J8Y16_RS23425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS23450	COG1842	Phage shock protein A
J8Y16_RS23490	COG5002	protein histidine kinase activity
J8Y16_RS23495	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS23520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J8Y16_RS23525	COG1597	lipid kinase activity
J8Y16_RS23540	COG0577	efflux transmembrane transporter activity
J8Y16_RS23545	COG1136	(ABC) transporter
J8Y16_RS23560	COG0586	Pfam SNARE associated Golgi protein
J8Y16_RS23570	COG0577	efflux transmembrane transporter activity
J8Y16_RS23575	COG1136	(ABC) transporter
J8Y16_RS23580	COG3708	Transcriptional regulator
J8Y16_RS23580	COG2207	Transcriptional regulator
J8Y16_RS23585	COG5658	integral membrane protein
J8Y16_RS23590	COG0640	Transcriptional regulator
J8Y16_RS23595	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS23600	COG2205	protein histidine kinase activity
J8Y16_RS23605	COG0577	efflux transmembrane transporter activity
J8Y16_RS23610	COG0577	efflux transmembrane transporter activity
J8Y16_RS23615	COG1136	(ABC) transporter
J8Y16_RS23620	COG0577	efflux transmembrane transporter activity
J8Y16_RS23645	COG2188	Transcriptional regulator
J8Y16_RS23665	COG3964	amidohydrolase
J8Y16_RS23675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J8Y16_RS23700	COG4948	Mandelate Racemase Muconate Lactonizing
J8Y16_RS23710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J8Y16_RS23715	COG0596	Alpha beta hydrolase
J8Y16_RS23725	COG1169	isochorismate synthase
J8Y16_RS23730	COG1575	Belongs to the MenA family. Type 1 subfamily
J8Y16_RS23735	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J8Y16_RS23765	COG0058	SHG alpha-glucan phosphorylase activity
J8Y16_RS23775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J8Y16_RS23795	COG1404	Belongs to the peptidase S8 family
J8Y16_RS23810	COG1595	DNA-templated transcription, initiation
J8Y16_RS23905	COG0544	peptidyl-prolyl cis-trans isomerase activity
J8Y16_RS23940	COG1285	pathogenesis
J8Y16_RS23945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8Y16_RS23960	COG2155	Conserved Protein
J8Y16_RS23965	COG1098	S1 RNA binding domain
J8Y16_RS23970	COG0436	Aminotransferase
J8Y16_RS23975	COG1522	sequence-specific DNA binding
J8Y16_RS23980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J8Y16_RS23985	COG2267	carboxylic ester hydrolase activity
J8Y16_RS23995	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J8Y16_RS24015	COG5018	Exonuclease
J8Y16_RS24020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Y16_RS24040	COG2050	protein possibly involved in aromatic compounds catabolism
J8Y16_RS24050	COG1268	BioY protein
J8Y16_RS24055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J8Y16_RS24060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J8Y16_RS24075	COG3584	3D domain protein
J8Y16_RS24090	COG1252	NADH dehydrogenase
J8Y16_RS24105	COG3708	Transcriptional regulator
J8Y16_RS24120	COG1683	Conserved Protein
J8Y16_RS24130	COG0316	Belongs to the HesB IscA family
J8Y16_RS24145	COG1252	NADH dehydrogenase
J8Y16_RS24155	COG2274	protein secretion by the type I secretion system
J8Y16_RS24160	COG0390	transport system, permease component
J8Y16_RS24165	COG2824	Alkylphosphonate utilization operon protein PhnA
J8Y16_RS24185	COG4837	Protein of unknown function (DUF1462)
J8Y16_RS24190	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J8Y16_RS24200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J8Y16_RS24205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J8Y16_RS24245	COG1136	(ABC) transporter
J8Y16_RS24265	COG1132	(ABC) transporter
J8Y16_RS24310	COG2249	NAD(P)H dehydrogenase (quinone) activity
J8Y16_RS24315	COG0647	UMP catabolic process
J8Y16_RS24325	COG2445	Protein of unknown function DUF86
J8Y16_RS24330	COG1494	fructose-1,6-bisphosphatase
J8Y16_RS24345	COG4470	Protein conserved in bacteria
J8Y16_RS24355	COG0789	Transcriptional regulator
J8Y16_RS24360	COG4377	Putative membrane peptidase family (DUF2324)
J8Y16_RS24385	COG0739	heme binding
J8Y16_RS24395	COG3377	Domain of unknown function (DUF1805)
J8Y16_RS24400	COG0737	Belongs to the 5'-nucleotidase family
J8Y16_RS24405	COG1695	Transcriptional regulator
J8Y16_RS24415	COG0719	Fe-S assembly protein
J8Y16_RS24420	COG0822	iron-sulfur transferase activity
J8Y16_RS24425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J8Y16_RS24430	COG0719	Fe-S assembly protein
J8Y16_RS24435	COG0396	ATPase activity
J8Y16_RS24440	COG1464	Belongs to the NlpA lipoprotein family
J8Y16_RS24445	COG1464	Belongs to the NlpA lipoprotein family
J8Y16_RS24450	COG2011	ABC-type metal ion transport system permease component
J8Y16_RS24455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J8Y16_RS24465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J8Y16_RS24470	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
J8Y16_RS24480	COG1393	Belongs to the ArsC family
J8Y16_RS24560	COG1309	transcriptional regulator
J8Y16_RS24565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J8Y16_RS24570	COG1960	acyl-CoA dehydrogenase activity
J8Y16_RS24575	COG0183	Belongs to the thiolase family
J8Y16_RS24580	COG1024	Enoyl-CoA hydratase
J8Y16_RS24580	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8Y16_RS24590	COG1686	Belongs to the peptidase S11 family
J8Y16_RS24605	COG0011	TIGRFAM Protein of
J8Y16_RS24610	COG0840	transmembrane signaling receptor activity
J8Y16_RS24630	COG2814	Major facilitator Superfamily
J8Y16_RS24635	COG0531	amino acid
J8Y16_RS24655	COG0706	membrane insertase activity
J8Y16_RS24665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
J8Y16_RS24700	COG0586	Pfam SNARE associated Golgi protein
J8Y16_RS24710	COG1376	ErfK ybiS ycfS ynhG family protein
J8Y16_RS24715	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS24720	COG5002	protein histidine kinase activity
J8Y16_RS24745	COG0840	transmembrane signaling receptor activity
J8Y16_RS24750	COG2151	metal-sulfur cluster biosynthetic enzyme
J8Y16_RS24755	COG3227	Zinc metalloprotease (Elastase)
J8Y16_RS24760	COG1741	Belongs to the pirin family
J8Y16_RS24775	COG0475	glutathione-regulated potassium exporter activity
J8Y16_RS24780	COG0490	domain, Protein
J8Y16_RS24785	COG1115	amino acid carrier protein
J8Y16_RS24790	COG0783	Belongs to the Dps family
J8Y16_RS24805	COG1611	Belongs to the LOG family
J8Y16_RS24820	COG2311	Membrane
J8Y16_RS24825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS24830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS24835	COG1115	amino acid carrier protein
J8Y16_RS24840	COG2910	NAD(P)H-binding
J8Y16_RS24855	COG0656	L-ascorbic acid biosynthetic process
J8Y16_RS24860	COG2814	Major facilitator Superfamily
J8Y16_RS24865	COG1733	regulation of RNA biosynthetic process
J8Y16_RS24875	COG1252	NADH dehydrogenase
J8Y16_RS24880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J8Y16_RS24905	COG0840	transmembrane signaling receptor activity
J8Y16_RS24905	COG3290	protein histidine kinase activity
J8Y16_RS24915	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J8Y16_RS24940	COG0488	(ABC) transporter
J8Y16_RS24945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J8Y16_RS24955	COG2814	Major facilitator Superfamily
J8Y16_RS25015	COG0557	exoribonuclease II activity
J8Y16_RS25020	COG1647	Serine aminopeptidase, S33
J8Y16_RS25025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J8Y16_RS25030	COG1346	cytolysis
J8Y16_RS25065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J8Y16_RS25080	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
J8Y16_RS25100	COG0457	Tetratricopeptide repeat
J8Y16_RS25135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J8Y16_RS25150	COG2323	membrane
J8Y16_RS25160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J8Y16_RS25170	COG0391	Required for morphogenesis under gluconeogenic growth conditions
J8Y16_RS25180	COG1051	belongs to the nudix hydrolase family
J8Y16_RS25190	COG0492	ferredoxin-NADP+ reductase activity
J8Y16_RS25195	COG0457	Tetratricopeptide repeat
J8Y16_RS25200	COG0110	maltose O-acetyltransferase activity
J8Y16_RS25220	COG1950	PFAM Membrane protein of
J8Y16_RS25230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J8Y16_RS25250	COG0789	Transcriptional regulator
J8Y16_RS25275	COG2855	membrane
J8Y16_RS25280	COG0583	DNA-binding transcription factor activity
J8Y16_RS25290	COG0655	NAD(P)H dehydrogenase (quinone) activity
J8Y16_RS25305	COG1132	(ABC) transporter
J8Y16_RS25310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Y16_RS25315	COG0793	Belongs to the peptidase S41A family
J8Y16_RS25315	COG3409	Peptidoglycan-binding domain 1 protein
J8Y16_RS25320	COG2177	Part of the ABC transporter FtsEX involved in
J8Y16_RS25325	COG2884	Cell division ATP-binding protein ftsE
J8Y16_RS25345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J8Y16_RS25350	COG1278	Cold shock
J8Y16_RS25355	COG1040	competence protein
J8Y16_RS25360	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
J8Y16_RS25370	COG1733	regulation of RNA biosynthetic process
J8Y16_RS25375	COG1307	EDD domain protein, DegV family
J8Y16_RS25380	COG1739	Uncharacterized protein family UPF0029
J8Y16_RS25385	COG1316	TRANSCRIPTIONal
J8Y16_RS25390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J8Y16_RS25395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J8Y16_RS25400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J8Y16_RS25410	COG3933	PFAM sigma-54 factor interaction domain-containing protein
J8Y16_RS25410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
J8Y16_RS25430	COG1486	melibiose metabolic process
J8Y16_RS25435	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y16_RS25440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y16_RS25450	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J8Y16_RS25460	COG1447	Phosphotransferase system cellobiose-specific component IIA
J8Y16_RS25470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
J8Y16_RS25475	COG1301	dicarboxylic acid transport
J8Y16_RS25485	COG0346	lactoylglutathione lyase activity
J8Y16_RS25505	COG1511	domain protein
J8Y16_RS25510	COG0583	DNA-binding transcription factor activity
J8Y16_RS25515	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
J8Y16_RS25530	COG1271	oxidase subunit
J8Y16_RS25535	COG1294	oxidase, subunit
J8Y16_RS25540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
J8Y16_RS25550	COG1620	l-lactate permease
J8Y16_RS25560	COG2389	metal-binding protein
J8Y16_RS25570	COG1368	sulfuric ester hydrolase activity
J8Y16_RS25580	COG0791	NLP P60 protein
J8Y16_RS25580	COG1388	LysM domain
J8Y16_RS25585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
J8Y16_RS25595	COG1215	transferase activity, transferring glycosyl groups
J8Y16_RS25600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Y16_RS25605	COG1388	LysM domain
J8Y16_RS25605	COG3584	3D domain protein
J8Y16_RS25630	COG4715	Zinc finger, swim domain protein
J8Y16_RS25635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J8Y16_RS25680	COG0577	efflux transmembrane transporter activity
J8Y16_RS25685	COG1136	(ABC) transporter
J8Y16_RS25710	COG5002	protein histidine kinase activity
J8Y16_RS25715	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS25720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J8Y16_RS25745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J8Y16_RS25750	COG1134	teichoic acid transport
J8Y16_RS25755	COG1682	transport, permease protein
J8Y16_RS25760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J8Y16_RS25780	COG1216	Glycosyl transferase, family 2
J8Y16_RS25780	COG1442	glycosyl transferase family 8
J8Y16_RS25800	COG1609	Transcriptional regulator
J8Y16_RS25805	COG0726	polysaccharide deacetylase
J8Y16_RS25815	COG0739	heme binding
J8Y16_RS25830	COG3279	Response regulator of the LytR AlgR family
J8Y16_RS25835	COG2385	sporulation resulting in formation of a cellular spore
J8Y16_RS25850	COG4836	Membrane
J8Y16_RS25855	COG1007	ATP synthesis coupled electron transport
J8Y16_RS25860	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8Y16_RS25865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J8Y16_RS25875	COG0839	Belongs to the complex I subunit 6 family
J8Y16_RS25895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J8Y16_RS25910	COG3300	MHYT domain
J8Y16_RS25910	COG5001	Diguanylate cyclase
J8Y16_RS25960	COG0356	it plays a direct role in the translocation of protons across the membrane
J8Y16_RS25995	COG0698	ribose 5-phosphate isomerase
J8Y16_RS26005	COG2190	(PTS) system
J8Y16_RS26010	COG2259	Doxx family
J8Y16_RS26015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J8Y16_RS26035	COG0009	L-threonylcarbamoyladenylate synthase
J8Y16_RS26050	COG2890	protein-(glutamine-N5) methyltransferase activity
J8Y16_RS26070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J8Y16_RS26075	COG1494	fructose-1,6-bisphosphatase
J8Y16_RS26095	COG4821	SIS domain
J8Y16_RS26115	COG1960	acyl-CoA dehydrogenase activity
J8Y16_RS26120	COG1960	acyl-CoA dehydrogenase activity
J8Y16_RS26125	COG1250	3-hydroxyacyl-CoA dehydrogenase
J8Y16_RS26130	COG0183	Belongs to the thiolase family
J8Y16_RS26135	COG2181	nitrate reductase activity
J8Y16_RS26135	COG0247	lactate metabolic process
J8Y16_RS26140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J8Y16_RS26150	COG5001	Diguanylate cyclase
J8Y16_RS26150	COG3300	MHYT domain
J8Y16_RS26170	COG2197	response regulator
J8Y16_RS26175	COG4585	Histidine kinase
J8Y16_RS26180	COG0842	Transport permease protein
J8Y16_RS26185	COG1131	(ABC) transporter
J8Y16_RS26190	COG0024	Methionine aminopeptidase
J8Y16_RS26200	COG2234	aminopeptidase activity
J8Y16_RS26220	COG1595	DNA-templated transcription, initiation
J8Y16_RS26230	COG4506	Protein conserved in bacteria
J8Y16_RS26235	COG1619	proteins homologs of microcin C7 resistance protein MccF
J8Y16_RS26250	COG0010	Belongs to the arginase family
J8Y16_RS26260	COG2814	Major facilitator Superfamily
J8Y16_RS26265	COG0789	Transcriptional regulator
J8Y16_RS26270	COG0584	glycerophosphoryl diester phosphodiesterase
J8Y16_RS26275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J8Y16_RS26285	COG1994	Peptidase M50
J8Y16_RS26295	COG1078	dGTPase activity
J8Y16_RS26300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J8Y16_RS26305	COG1120	ATPase activity
J8Y16_RS26310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS26315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J8Y16_RS26335	COG0095	Lipoate-protein ligase
J8Y16_RS26340	COG0280	phosphate acetyltransferase
J8Y16_RS26355	COG3773	Cell wall hydrolase
J8Y16_RS26365	COG2363	Small membrane protein
J8Y16_RS26375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J8Y16_RS26380	COG2233	PERMEase
J8Y16_RS26385	COG0561	phosphatase activity
J8Y16_RS26390	COG2814	Major facilitator Superfamily
J8Y16_RS26400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
J8Y16_RS26405	COG1131	(ABC) transporter
J8Y16_RS26410	COG2755	lipolytic protein G-D-S-L family
J8Y16_RS26415	COG1609	Transcriptional regulator
J8Y16_RS26425	COG0460	homoserine dehydrogenase
J8Y16_RS26435	COG2873	o-acetylhomoserine
J8Y16_RS26440	COG1011	Hydrolase
J8Y16_RS26445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J8Y16_RS26455	COG2197	response regulator
J8Y16_RS26460	COG4585	Histidine kinase
J8Y16_RS26460	COG2203	Gaf domain
J8Y16_RS26465	COG0351	phosphomethylpyrimidine kinase
J8Y16_RS26470	COG3706	GGDEF domain
J8Y16_RS26475	COG2879	small protein
J8Y16_RS26480	COG1966	Carbon starvation protein
J8Y16_RS26485	COG3279	Response regulator of the LytR AlgR family
J8Y16_RS26490	COG0477	Major facilitator Superfamily
J8Y16_RS26515	COG0840	transmembrane signaling receptor activity
J8Y16_RS26525	COG1607	acyl-coa hydrolase
J8Y16_RS26540	COG0488	(ABC) transporter
J8Y16_RS26560	COG0463	Glycosyl transferase, family 2
J8Y16_RS26565	COG1309	transcriptional regulator
J8Y16_RS26570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J8Y16_RS26575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Y16_RS26575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J8Y16_RS26580	COG0628	permease
J8Y16_RS26595	COG3279	Response regulator of the LytR AlgR family
J8Y16_RS26600	COG3275	phosphorelay sensor kinase activity
J8Y16_RS26605	COG2814	Major facilitator Superfamily
J8Y16_RS26610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J8Y16_RS26615	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
J8Y16_RS26620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J8Y16_RS26640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J8Y16_RS26645	COG1272	protein, Hemolysin III
J8Y16_RS26670	COG1164	Oligoendopeptidase f
J8Y16_RS26690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J8Y16_RS26695	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J8Y16_RS26700	COG4853	Protein conserved in bacteria
J8Y16_RS26705	COG4863	YycH protein
J8Y16_RS26710	COG5002	protein histidine kinase activity
J8Y16_RS26715	COG0745	RESPONSE REGULATOR receiver
J8Y16_RS26745	COG0305	Participates in initiation and elongation during chromosome replication
J8Y16_RS26755	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
J8Y16_RS26760	COG4241	membrane
J8Y16_RS26770	COG0629	single-stranded DNA binding
J8Y16_RS26780	COG0012	GTP binding
J8Y16_RS26785	COG4481	Protein conserved in bacteria
J8Y16_RS26790	COG0668	transmembrane transport
J8Y16_RS26800	COG1475	DNA binding
J8Y16_RS26805	COG1192	Involved in chromosome partitioning
J8Y16_RS26830	COG1847	R3H domain protein
J8Y16_RS26835	COG0706	membrane insertase activity
J8Y16_RS26845	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J8Y16_RS27025	COG1403	HNH endonuclease
J8Y16_RS27085	COG1388	LysM domain
J8Y16_RS27085	COG3584	3D domain protein