locus-tag	class	description
WR51_RS00010	COG0592	DNA-directed DNA polymerase activity
WR51_RS00015	COG2501	S4 domain
WR51_RS00025	COG0187	DNA topoisomerase II activity
WR51_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR51_RS00065	COG0517	IMP dehydrogenase activity
WR51_RS00065	COG0516	GMP reductase activity
WR51_RS00070	COG1686	Belongs to the peptidase S11 family
WR51_RS00100	COG1428	Deoxynucleoside kinase
WR51_RS00105	COG1428	Deoxynucleoside kinase
WR51_RS00110	COG1335	isochorismatase
WR51_RS00115	COG0590	tRNA wobble adenosine to inosine editing
WR51_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WR51_RS00180	COG1982	Orn Lys Arg decarboxylase major
WR51_RS00190	COG0470	DNA polymerase III
WR51_RS00195	COG1774	PSP1 C-terminal conserved region
WR51_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WR51_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WR51_RS00220	COG2002	toxin-antitoxin pair type II binding
WR51_RS00230	COG0084	hydrolase, TatD family'
WR51_RS00250	COG4466	Protein conserved in bacteria
WR51_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WR51_RS00270	COG0251	oxidation-reduction process
WR51_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WR51_RS00305	COG2002	toxin-antitoxin pair type II binding
WR51_RS00310	COG2244	polysaccharide biosynthetic process
WR51_RS00315	COG3956	TIGRFAM MazG family protein
WR51_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
WR51_RS00340	COG1098	S1 RNA binding domain
WR51_RS00355	COG2208	phosphoserine phosphatase activity
WR51_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WR51_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WR51_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WR51_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
WR51_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WR51_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WR51_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WR51_RS00420	COG1396	sequence-specific DNA binding
WR51_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WR51_RS00515	COG3880	PFAM UvrB UvrC protein
WR51_RS00525	COG0542	response to heat
WR51_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WR51_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
WR51_RS00560	COG1045	serine acetyltransferase
WR51_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WR51_RS00580	COG3688	RNA-binding protein containing a PIN domain
WR51_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WR51_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
WR51_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WR51_RS00615	COG0222	ribosome binding
WR51_RS00620	COG2813	Specifically methylates the guanine in position
WR51_RS00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WR51_RS00635	COG1358	cellular component organization or biogenesis
WR51_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WR51_RS00660	COG0051	transcription antitermination factor activity, RNA binding
WR51_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WR51_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
WR51_RS00765	COG0201	protein transport
WR51_RS00775	COG0024	Methionine aminopeptidase
WR51_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WR51_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WR51_RS00845	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_RS00850	COG0489	protein tyrosine kinase activity
WR51_RS00860	COG2194	sulfuric ester hydrolase activity
WR51_RS00865	COG0726	polysaccharide deacetylase
WR51_RS00945	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
WR51_RS00950	COG4856	YbbR-like protein
WR51_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS00995	COG2011	ABC-type metal ion transport system permease component
WR51_RS01000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WR51_RS01005	COG1464	Belongs to the NlpA lipoprotein family
WR51_RS01010	COG0604	alcohol dehydrogenase
WR51_RS01020	COG0277	FAD linked oxidase domain protein
WR51_RS01025	COG2271	Major facilitator Superfamily
WR51_RS01035	COG2814	Major facilitator Superfamily
WR51_RS01055	COG0601	transmembrane transport
WR51_RS01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_RS01065	COG0444	Belongs to the ABC transporter superfamily
WR51_RS01070	COG4608	Belongs to the ABC transporter superfamily
WR51_RS01075	COG4166	transmembrane transport
WR51_RS01085	COG4166	transmembrane transport
WR51_RS01090	COG4166	transmembrane transport
WR51_RS01095	COG0656	L-ascorbic acid biosynthetic process
WR51_RS01115	COG4149	molybdate abc transporter
WR51_RS01120	COG0725	ABC transporter, periplasmic molybdate-binding protein
WR51_RS01125	COG1910	domain protein
WR51_RS01135	COG0697	spore germination
WR51_RS01145	COG0204	Acyl-transferase
WR51_RS01150	COG1609	Transcriptional regulator
WR51_RS01160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS01180	COG5298	Protein conserved in bacteria
WR51_RS01200	COG0488	(ABC) transporter
WR51_RS01210	COG0747	negative chemotaxis
WR51_RS01215	COG0601	transmembrane transport
WR51_RS01220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_RS01225	COG0444	Belongs to the ABC transporter superfamily
WR51_RS01230	COG4608	Belongs to the ABC transporter superfamily
WR51_RS01235	COG0561	phosphatase activity
WR51_RS01265	COG3185	4-Hydroxyphenylpyruvate dioxygenase
WR51_RS01270	COG0179	Fumarylacetoacetate (FAA) hydrolase
WR51_RS01280	COG0531	amino acid
WR51_RS01285	COG2814	Major facilitator Superfamily
WR51_RS01295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WR51_RS01305	COG4294	response to UV
WR51_RS01310	COG0705	Rhomboid family
WR51_RS01320	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WR51_RS01325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR51_RS01330	COG0864	Transcriptional regulator
WR51_RS01335	COG2337	Toxic component of a toxin-antitoxin (TA) module
WR51_RS01340	COG2183	response to ionizing radiation
WR51_RS01435	COG0802	atpase or kinase
WR51_RS01440	COG1214	PFAM Peptidase M22, glycoprotease
WR51_RS01445	COG0456	acetyltransferase
WR51_RS01455	COG0488	(ABC) transporter
WR51_RS01470	COG1266	CAAX protease self-immunity
WR51_RS01500	COG2252	PERMEase
WR51_RS01510	COG5002	protein histidine kinase activity
WR51_RS01535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR51_RS01555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS01560	COG0506	proline dehydrogenase activity
WR51_RS01605	COG2205	protein histidine kinase activity
WR51_RS01610	COG0745	RESPONSE REGULATOR receiver
WR51_RS01630	COG0697	spore germination
WR51_RS01660	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WR51_RS01665	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WR51_RS01670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WR51_RS01680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WR51_RS01695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WR51_RS01705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WR51_RS01715	COG0151	Belongs to the GarS family
WR51_RS01725	COG0583	DNA-binding transcription factor activity
WR51_RS01750	COG0210	DNA helicase
WR51_RS01760	COG4851	CamS sex pheromone cAM373 precursor
WR51_RS01775	COG1335	isochorismatase
WR51_RS01785	COG2011	ABC-type metal ion transport system permease component
WR51_RS01790	COG1464	Belongs to the NlpA lipoprotein family
WR51_RS01800	COG0003	Pfam Anion-transporting ATPase
WR51_RS01805	COG1846	Transcriptional regulator
WR51_RS01810	COG4682	membrane
WR51_RS01830	COG1597	lipid kinase activity
WR51_RS01835	COG0546	phosphoglycolate phosphatase activity
WR51_RS01840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
WR51_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS01855	COG2076	Multidrug Resistance protein
WR51_RS01860	COG2309	aminopeptidase activity
WR51_RS01875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS01885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WR51_RS01890	COG4807	Protein conserved in bacteria
WR51_RS01915	COG1757	Na H antiporter
WR51_RS01920	COG1473	amidohydrolase
WR51_RS01940	COG0450	alkyl hydroperoxide reductase
WR51_RS01960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS01965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS01970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS01975	COG0492	ferredoxin-NADP+ reductase activity
WR51_RS01985	COG0166	Belongs to the GPI family
WR51_RS02010	COG5002	protein histidine kinase activity
WR51_RS02030	COG3541	Predicted nucleotidyltransferase
WR51_RS02035	COG2814	Major facilitator Superfamily
WR51_RS02040	COG0723	plastoquinol--plastocyanin reductase activity
WR51_RS02040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_RS02050	COG0765	amino acid transport
WR51_RS02055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_RS02065	COG0840	transmembrane signaling receptor activity
WR51_RS02090	COG0549	Belongs to the carbamate kinase family
WR51_RS02095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_RS02105	COG0277	FAD linked oxidase domain protein
WR51_RS02110	COG0366	Alpha amylase catalytic
WR51_RS02115	COG1263	PTS System
WR51_RS02115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_RS02115	COG2190	(PTS) system
WR51_RS02145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WR51_RS02165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_RS02170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_RS02175	COG1116	anion transmembrane transporter activity
WR51_RS02180	COG0488	(ABC) transporter
WR51_RS02225	COG2270	Major facilitator Superfamily
WR51_RS02255	COG2310	stress, protein
WR51_RS02260	COG2310	stress, protein
WR51_RS02265	COG2310	stress, protein
WR51_RS02270	COG0861	Integral membrane protein TerC family
WR51_RS02280	COG3853	Toxic anion resistance protein (TelA)
WR51_RS02295	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
WR51_RS02305	COG1295	ribonuclease BN
WR51_RS02310	COG2217	Heavy metal translocating P-type atpase
WR51_RS02315	COG0697	spore germination
WR51_RS02335	COG0586	Pfam SNARE associated Golgi protein
WR51_RS02350	COG3871	stress protein (general stress protein 26)
WR51_RS02355	COG0387	Pfam Sodium calcium exchanger
WR51_RS02365	COG0535	radical SAM domain protein
WR51_RS02385	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WR51_RS02390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WR51_RS02405	COG3829	transcription factor binding
WR51_RS02415	COG0833	amino acid
WR51_RS02420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR51_RS02445	COG1263	PTS System
WR51_RS02445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_RS02450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_RS02465	COG1216	Glycosyl transferase, family 2
WR51_RS02475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_RS02475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WR51_RS02480	COG0463	Glycosyl transferase, family 2
WR51_RS02490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WR51_RS02510	COG1228	amidohydrolase
WR51_RS02515	COG1090	epimerase
WR51_RS02545	COG1988	membrane-bound metal-dependent
WR51_RS02550	COG1194	a g-specific adenine glycosylase
WR51_RS02570	COG3557	Belongs to the UPF0374 family
WR51_RS02575	COG1132	(ABC) transporter
WR51_RS02580	COG4129	membrane
WR51_RS02585	COG0069	glutamate synthase activity
WR51_RS02585	COG0067	glutamate synthase
WR51_RS02585	COG0070	glutamate synthase
WR51_RS02595	COG4555	ABC transporter
WR51_RS02615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WR51_RS02620	COG0735	belongs to the Fur family
WR51_RS02800	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WR51_RS02825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WR51_RS02830	COG1716	ATPase activity
WR51_RS02830	COG5001	Diguanylate cyclase
WR51_RS02835	COG2766	serine protein kinase
WR51_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS02875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR51_RS02875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_RS02875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_RS02875	COG3321	synthase
WR51_RS02880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_RS02880	COG3321	synthase
WR51_RS02880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR51_RS02880	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS02880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_RS02905	COG2801	Transposase and inactivated derivatives
WR51_RS02930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR51_RS02940	COG1585	Membrane protein implicated in regulation of membrane protease activity
WR51_RS02945	COG2268	Band 7 protein
WR51_RS02955	COG3290	protein histidine kinase activity
WR51_RS02960	COG4565	transcriptional regulatory protein
WR51_RS02965	COG2851	Citrate transporter
WR51_RS02990	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WR51_RS02995	COG3842	ATPase activity
WR51_RS03000	COG1175	transmembrane transport
WR51_RS03005	COG0395	ABC-type sugar transport system, permease component
WR51_RS03015	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WR51_RS03020	COG0745	RESPONSE REGULATOR receiver
WR51_RS03025	COG5002	protein histidine kinase activity
WR51_RS03035	COG4990	cell redox homeostasis
WR51_RS03045	COG3290	protein histidine kinase activity
WR51_RS03050	COG4565	transcriptional regulatory protein
WR51_RS03055	COG3493	citrate carrier protein
WR51_RS03060	COG0281	malic enzyme
WR51_RS03070	COG0697	spore germination
WR51_RS03075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS03085	COG5002	protein histidine kinase activity
WR51_RS03090	COG0745	RESPONSE REGULATOR receiver
WR51_RS03100	COG0454	-acetyltransferase
WR51_RS03100	COG0456	acetyltransferase
WR51_RS03105	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WR51_RS03110	COG3383	formate dehydrogenase (NAD+) activity
WR51_RS03115	COG2427	Protein of unknown function (DUF1641)
WR51_RS03130	COG0531	amino acid
WR51_RS03140	COG0640	Transcriptional regulator
WR51_RS03145	COG2217	Heavy metal translocating P-type atpase
WR51_RS03150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
WR51_RS03160	COG3227	Zinc metalloprotease (Elastase)
WR51_RS03180	COG2720	vancomycin resistance protein
WR51_RS03185	COG1316	TRANSCRIPTIONal
WR51_RS03190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS03195	COG0346	lactoylglutathione lyase activity
WR51_RS03200	COG1253	flavin adenine dinucleotide binding
WR51_RS03205	COG1027	Aspartate ammonia-lyase
WR51_RS03210	COG1620	l-lactate permease
WR51_RS03225	COG3104	oligopeptide transport
WR51_RS03230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS03235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS03240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS03255	COG0156	8-amino-7-oxononanoate synthase activity
WR51_RS03260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_RS03265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WR51_RS03275	COG4548	von Willebrand factor, type A
WR51_RS03280	COG0714	Associated with various cellular activities
WR51_RS03300	COG0531	amino acid
WR51_RS03305	COG2188	Transcriptional regulator
WR51_RS03310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_RS03310	COG1263	PTS System
WR51_RS03315	COG0366	Alpha amylase catalytic
WR51_RS03330	COG0697	spore germination
WR51_RS03340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR51_RS03345	COG1115	amino acid carrier protein
WR51_RS03350	COG1126	abc transporter atp-binding protein
WR51_RS03355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_RS03360	COG0765	amino acid transport
WR51_RS03365	COG0765	amino acid transport
WR51_RS03370	COG0833	amino acid
WR51_RS03385	COG1595	DNA-templated transcription, initiation
WR51_RS03395	COG2378	regulation of single-species biofilm formation
WR51_RS03400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
WR51_RS03405	COG5002	protein histidine kinase activity
WR51_RS03430	COG0659	secondary active sulfate transmembrane transporter activity
WR51_RS03445	COG0747	negative chemotaxis
WR51_RS03455	COG0601	transmembrane transport
WR51_RS03460	COG4608	Belongs to the ABC transporter superfamily
WR51_RS03470	COG2271	Major facilitator Superfamily
WR51_RS03475	COG1846	Transcriptional regulator
WR51_RS03480	COG0477	Major facilitator Superfamily
WR51_RS03485	COG1609	Transcriptional regulator
WR51_RS03490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WR51_RS03505	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR51_RS03510	COG1879	ABC-type sugar transport system periplasmic component
WR51_RS03535	COG1063	alcohol dehydrogenase
WR51_RS03585	COG0840	transmembrane signaling receptor activity
WR51_RS03590	COG1388	LysM domain
WR51_RS03590	COG3584	3D domain protein
WR51_RS03595	COG1476	TRANSCRIPTIONal
WR51_RS03615	COG3104	oligopeptide transport
WR51_RS03620	COG1114	Component of the transport system for branched-chain amino acids
WR51_RS03635	COG1113	amino acid transport
WR51_RS03640	COG2252	PERMEase
WR51_RS03655	COG2153	protein acetylation
WR51_RS03665	COG0569	domain protein
WR51_RS03665	COG0475	glutathione-regulated potassium exporter activity
WR51_RS03675	COG1845	cytochrome c oxidase, subunit III
WR51_RS03680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WR51_RS03690	COG0833	amino acid
WR51_RS03695	COG4990	cell redox homeostasis
WR51_RS03710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_RS03715	COG0697	spore germination
WR51_RS03720	COG0531	amino acid
WR51_RS03730	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR51_RS03735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR51_RS03740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
WR51_RS03740	COG1918	ferrous iron import across plasma membrane
WR51_RS03745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WR51_RS03755	COG0581	inorganic phosphate transmembrane transporter activity
WR51_RS03765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WR51_RS03885	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
WR51_RS03905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WR51_RS03910	COG1116	anion transmembrane transporter activity
WR51_RS03915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_RS03920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_RS03925	COG0352	thiamine-phosphate diphosphorylase activity
WR51_RS03930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_RS03935	COG2104	thiamine diphosphate biosynthetic process
WR51_RS03945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_RS03950	COG0351	phosphomethylpyrimidine kinase
WR51_RS03990	COG2205	protein histidine kinase activity
WR51_RS03995	COG2814	Major facilitator Superfamily
WR51_RS04000	COG1846	Transcriptional regulator
WR51_RS04015	COG2801	Transposase and inactivated derivatives
WR51_RS04025	COG2252	PERMEase
WR51_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS04090	COG0778	Nitroreductase
WR51_RS04095	COG2719	SpoVR family
WR51_RS04105	COG1414	Transcriptional regulator
WR51_RS04120	COG0446	pyridine nucleotide-disulphide oxidoreductase
WR51_RS04125	COG1937	Protein conserved in bacteria
WR51_RS04130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_RS04130	COG0425	Belongs to the sulfur carrier protein TusA family
WR51_RS04135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_RS04140	COG0425	Belongs to the sulfur carrier protein TusA family
WR51_RS04145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_RS04155	COG2210	Belongs to the sulfur carrier protein TusA family
WR51_RS04160	COG0730	response to heat
WR51_RS04170	COG1316	TRANSCRIPTIONal
WR51_RS04175	COG0604	alcohol dehydrogenase
WR51_RS04180	COG1283	sodium-dependent phosphate transmembrane transporter activity
WR51_RS04195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_RS04195	COG3711	transcriptional antiterminator
WR51_RS04200	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR51_RS04205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR51_RS04225	COG3584	3D domain protein
WR51_RS04225	COG1388	LysM domain
WR51_RS04230	COG0577	efflux transmembrane transporter activity
WR51_RS04235	COG1136	(ABC) transporter
WR51_RS04245	COG5522	Integral membrane protein (intg_mem_TP0381)
WR51_RS04260	COG1114	Component of the transport system for branched-chain amino acids
WR51_RS04265	COG3546	catalase activity
WR51_RS04300	COG0586	Pfam SNARE associated Golgi protein
WR51_RS04330	COG0531	amino acid
WR51_RS04335	COG0475	glutathione-regulated potassium exporter activity
WR51_RS04345	COG1737	Transcriptional regulator
WR51_RS04355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_RS04355	COG1263	PTS System
WR51_RS04365	COG2259	Doxx family
WR51_RS04385	COG1522	sequence-specific DNA binding
WR51_RS04390	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WR51_RS04390	COG0165	Argininosuccinate lyase
WR51_RS04395	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS04415	COG1309	transcriptional regulator
WR51_RS04420	COG2814	Major facilitator Superfamily
WR51_RS04425	COG1733	regulation of RNA biosynthetic process
WR51_RS04445	COG0693	protein deglycase activity
WR51_RS04450	COG0753	catalase activity
WR51_RS04460	COG0531	amino acid
WR51_RS04475	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS04480	COG1132	(ABC) transporter
WR51_RS04485	COG1132	(ABC) transporter
WR51_RS04490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_RS04495	COG0765	amino acid transport
WR51_RS04500	COG1126	abc transporter atp-binding protein
WR51_RS04515	COG0189	ligase activity
WR51_RS04535	COG4585	Histidine kinase
WR51_RS04540	COG2197	response regulator
WR51_RS04560	COG0028	Belongs to the TPP enzyme family
WR51_RS04565	COG3527	Alpha-acetolactate decarboxylase
WR51_RS04575	COG0561	phosphatase activity
WR51_RS04585	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_RS04585	COG3409	Peptidoglycan-binding domain 1 protein
WR51_RS04590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WR51_RS04595	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_RS04610	COG0659	secondary active sulfate transmembrane transporter activity
WR51_RS04615	COG2244	polysaccharide biosynthetic process
WR51_RS04635	COG1024	Enoyl-CoA hydratase
WR51_RS04655	COG1363	Peptidase, m42
WR51_RS04695	COG0601	transmembrane transport
WR51_RS04700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_RS04705	COG0444	Belongs to the ABC transporter superfamily
WR51_RS04710	COG4608	Belongs to the ABC transporter superfamily
WR51_RS04750	COG0477	Major facilitator Superfamily
WR51_RS04755	COG3290	protein histidine kinase activity
WR51_RS04760	COG4565	transcriptional regulatory protein
WR51_RS04765	COG3181	Tripartite tricarboxylate transporter family receptor
WR51_RS04825	COG0305	Participates in initiation and elongation during chromosome replication
WR51_RS04855	COG0477	Major facilitator Superfamily
WR51_RS04865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS04880	COG5504	Zn-dependent protease
WR51_RS04885	COG0789	Transcriptional regulator
WR51_RS04920	COG1329	Transcriptional regulator
WR51_RS04935	COG1278	Cold shock
WR51_RS04950	COG1131	(ABC) transporter
WR51_RS05000	COG1073	alpha beta
WR51_RS05040	COG1183	phosphatidylcholine synthase activity
WR51_RS05055	COG2814	Major facilitator Superfamily
WR51_RS05060	COG0640	Transcriptional regulator
WR51_RS05070	COG2376	Dihydroxyacetone kinase
WR51_RS05080	COG2376	Dihydroxyacetone kinase
WR51_RS05110	COG0457	Tetratricopeptide repeat
WR51_RS05115	COG2373	Large extracellular alpha-helical protein
WR51_RS05155	COG3237	CsbD-like
WR51_RS05180	COG1191	sigma factor activity
WR51_RS05190	COG2208	phosphoserine phosphatase activity
WR51_RS05195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WR51_RS05200	COG2198	Histidine kinase
WR51_RS05200	COG2205	protein histidine kinase activity
WR51_RS05200	COG0784	Response regulator, receiver
WR51_RS05235	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
WR51_RS05255	COG0420	3'-5' exonuclease activity
WR51_RS05260	COG4717	serine-type aminopeptidase activity
WR51_RS05275	COG1280	lysine exporter protein (LysE YggA)
WR51_RS05280	COG0346	lactoylglutathione lyase activity
WR51_RS05285	COG0346	lactoylglutathione lyase activity
WR51_RS05295	COG0457	Tetratricopeptide repeat
WR51_RS05305	COG2267	carboxylic ester hydrolase activity
WR51_RS05320	COG2140	Oxalate decarboxylase
WR51_RS05325	COG3620	sequence-specific DNA binding
WR51_RS05335	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
WR51_RS05340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WR51_RS05350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WR51_RS05355	COG1595	DNA-templated transcription, initiation
WR51_RS05365	COG0772	Belongs to the SEDS family
WR51_RS05370	COG3973	AAA domain
WR51_RS05395	COG4980	gas vesicle protein
WR51_RS05400	COG0537	adenosine 5'-monophosphoramidase activity
WR51_RS05405	COG1131	(ABC) transporter
WR51_RS05410	COG4473	ABC transporter
WR51_RS05460	COG1309	transcriptional regulator
WR51_RS05470	COG3402	PFAM membrane-flanked domain
WR51_RS05475	COG3428	Bacterial PH domain
WR51_RS05515	COG0697	spore germination
WR51_RS05520	COG3402	PFAM membrane-flanked domain
WR51_RS05525	COG3428	Bacterial PH domain
WR51_RS05530	COG2329	Antibiotic biosynthesis monooxygenase
WR51_RS05535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_RS05550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
WR51_RS05585	COG1309	transcriptional regulator
WR51_RS05590	COG1511	domain protein
WR51_RS05610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS05615	COG1609	Transcriptional regulator
WR51_RS05625	COG1234	tRNA 3'-trailer cleavage
WR51_RS05630	COG0095	Lipoate-protein ligase
WR51_RS05640	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_RS05650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WR51_RS05660	COG4208	sulfate ABC transporter
WR51_RS05675	COG1408	metallophosphoesterase
WR51_RS05680	COG1078	dGTPase activity
WR51_RS05690	COG1595	DNA-templated transcription, initiation
WR51_RS05695	COG3708	Transcriptional regulator
WR51_RS05695	COG2207	Transcriptional regulator
WR51_RS05705	COG2205	protein histidine kinase activity
WR51_RS05710	COG0745	RESPONSE REGULATOR receiver
WR51_RS05730	COG0501	Belongs to the peptidase M48B family
WR51_RS05735	COG0840	transmembrane signaling receptor activity
WR51_RS05740	COG3693	PFAM glycoside hydrolase, family 10
WR51_RS05750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WR51_RS05755	COG2224	Isocitrate lyase
WR51_RS05770	COG1278	Cold shock
WR51_RS05790	COG0398	Pfam SNARE associated Golgi protein
WR51_RS05810	COG0202	RNA polymerase activity
WR51_RS05850	COG0179	Fumarylacetoacetate (FAA) hydrolase
WR51_RS05875	COG0367	asparagine synthase
WR51_RS05885	COG0753	catalase activity
WR51_RS05890	COG0004	ammonium transporteR
WR51_RS05910	COG2996	Protein conserved in bacteria
WR51_RS05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS05935	COG0561	phosphatase activity
WR51_RS05955	COG2267	carboxylic ester hydrolase activity
WR51_RS05970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR51_RS05975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WR51_RS05980	COG5504	Zn-dependent protease
WR51_RS05990	COG0180	Tryptophanyl-tRNA synthetase
WR51_RS06000	COG4166	transmembrane transport
WR51_RS06005	COG0601	transmembrane transport
WR51_RS06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WR51_RS06015	COG0444	Belongs to the ABC transporter superfamily
WR51_RS06020	COG4608	Belongs to the ABC transporter superfamily
WR51_RS06025	COG0534	Mate efflux family protein
WR51_RS06030	COG4166	transmembrane transport
WR51_RS06045	COG0861	Integral membrane protein TerC family
WR51_RS06055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_RS06065	COG1164	Oligoendopeptidase f
WR51_RS06075	COG2346	COG2346, Truncated hemoglobins
WR51_RS06080	COG4116	CYTH
WR51_RS06090	COG2357	RelA SpoT domain protein
WR51_RS06100	COG0564	pseudouridine synthase activity
WR51_RS06115	COG0772	Belongs to the SEDS family
WR51_RS06120	COG1216	Glycosyl transferase, family 2
WR51_RS06140	COG0463	Glycosyl transferase, family 2
WR51_RS06140	COG0457	Tetratricopeptide repeat
WR51_RS06160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WR51_RS06175	COG1091	dTDP-4-dehydrorhamnose reductase activity
WR51_RS06220	COG2153	protein acetylation
WR51_RS06230	COG2382	esterase
WR51_RS06260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_RS06270	COG0512	Glutamine amidotransferase of anthranilate synthase
WR51_RS06270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WR51_RS06315	COG1620	l-lactate permease
WR51_RS06325	COG5634	Uncharacterized conserved protein (DUF2278)
WR51_RS06375	COG2226	methyltransferase
WR51_RS06395	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR51_RS06405	COG1476	TRANSCRIPTIONal
WR51_RS06465	COG2226	methyltransferase
WR51_RS06475	COG1686	Belongs to the peptidase S11 family
WR51_RS06480	COG0681	Belongs to the peptidase S26 family
WR51_RS06515	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS06525	COG1176	ABC-type spermidine putrescine transport system, permease component I
WR51_RS06530	COG1177	transmembrane transport
WR51_RS06545	COG2409	Drug exporters of the RND superfamily
WR51_RS06555	COG0564	pseudouridine synthase activity
WR51_RS06565	COG2340	Cysteine-rich secretory protein family
WR51_RS06570	COG0247	lactate metabolic process
WR51_RS06575	COG0277	FAD linked oxidase domain protein
WR51_RS06580	COG3835	regulator
WR51_RS06590	COG0745	RESPONSE REGULATOR receiver
WR51_RS06595	COG5002	protein histidine kinase activity
WR51_RS06600	COG2186	Transcriptional regulator
WR51_RS06620	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
WR51_RS06630	COG2116	formate transmembrane transporter activity
WR51_RS06635	COG0861	Integral membrane protein TerC family
WR51_RS06640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR51_RS06650	COG2030	dehydratase
WR51_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS06675	COG3243	poly(R)-hydroxyalkanoic acid synthase
WR51_RS06685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR51_RS06700	COG1840	ABC-type Fe3 transport system, periplasmic component
WR51_RS06705	COG3842	ATPase activity
WR51_RS06730	COG1349	DNA-binding transcription factor activity
WR51_RS06745	COG0235	Class ii aldolase
WR51_RS06755	COG2861	carbohydrate metabolic process
WR51_RS06765	COG3852	Histidine kinase
WR51_RS06770	COG1846	Transcriptional regulator
WR51_RS06780	COG2318	DinB family
WR51_RS06790	COG5002	protein histidine kinase activity
WR51_RS06800	COG0720	synthase
WR51_RS06815	COG4873	Protein conserved in bacteria
WR51_RS06845	COG1780	Probably involved in ribonucleotide reductase function
WR51_RS06850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WR51_RS06855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WR51_RS06860	COG1725	Transcriptional regulator
WR51_RS06865	COG1131	(ABC) transporter
WR51_RS06875	COG1131	(ABC) transporter
WR51_RS06895	COG1522	sequence-specific DNA binding
WR51_RS06905	COG1335	isochorismatase
WR51_RS06915	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR51_RS06920	COG2070	2-Nitropropane dioxygenase
WR51_RS06925	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WR51_RS06935	COG1696	Membrane protein involved in D-alanine export
WR51_RS06960	COG0716	FMN binding
WR51_RS07015	COG1846	Transcriptional regulator
WR51_RS07025	COG1301	dicarboxylic acid transport
WR51_RS07030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WR51_RS07035	COG4709	membrane
WR51_RS07040	COG3874	Sporulation protein YtfJ
WR51_RS07060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_RS07065	COG0028	Belongs to the TPP enzyme family
WR51_RS07070	COG0440	acetolactate synthase activity
WR51_RS07145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WR51_RS07160	COG1183	phosphatidylcholine synthase activity
WR51_RS07165	COG1368	sulfuric ester hydrolase activity
WR51_RS07175	COG0019	diaminopimelate decarboxylase activity
WR51_RS07195	COG0529	Catalyzes the synthesis of activated sulfate
WR51_RS07200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WR51_RS07220	COG1648	precorrin-2 dehydrogenase activity
WR51_RS07225	COG0733	neurotransmitter:sodium symporter activity
WR51_RS07245	COG1757	Na H antiporter
WR51_RS07260	COG4758	membrane
WR51_RS07265	COG4585	Histidine kinase
WR51_RS07270	COG2197	response regulator
WR51_RS07280	COG1114	Component of the transport system for branched-chain amino acids
WR51_RS07290	COG2226	methyltransferase
WR51_RS07330	COG0730	response to heat
WR51_RS07335	COG0306	phosphate transporter
WR51_RS07340	COG1392	Phosphate transport regulator
WR51_RS07345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_RS07360	COG3852	Histidine kinase
WR51_RS07365	COG1801	Protein of unknown function DUF72
WR51_RS07375	COG0582	viral genome integration into host DNA
WR51_RS07380	COG5002	protein histidine kinase activity
WR51_RS07395	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WR51_RS07395	COG0392	lysyltransferase activity
WR51_RS07410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WR51_RS07415	COG1686	Belongs to the peptidase S11 family
WR51_RS07420	COG2715	membrane protein required for spore maturation
WR51_RS07425	COG0700	Nucleoside recognition
WR51_RS07430	COG1187	pseudouridine synthase activity
WR51_RS07440	COG1333	cytochrome c biogenesis protein
WR51_RS07445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WR51_RS07450	COG0745	RESPONSE REGULATOR receiver
WR51_RS07455	COG5002	protein histidine kinase activity
WR51_RS07460	COG2096	Adenosyltransferase
WR51_RS07475	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
WR51_RS07480	COG1141	Ferredoxin
WR51_RS07490	COG0514	ATP-dependent DNA helicase (RecQ)
WR51_RS07495	COG1266	CAAX protease self-immunity
WR51_RS07505	COG1408	metallophosphoesterase
WR51_RS07510	COG0789	Transcriptional regulator
WR51_RS07520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
WR51_RS07540	COG0492	ferredoxin-NADP+ reductase activity
WR51_RS07545	COG0252	asparaginase activity
WR51_RS07610	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR51_RS07625	COG0142	geranyltranstransferase activity
WR51_RS07635	COG0142	geranyltranstransferase activity
WR51_RS07660	COG0457	Tetratricopeptide repeat
WR51_RS07680	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WR51_RS07685	COG2010	Cytochrome c
WR51_RS07685	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WR51_RS07690	COG4347	Protein of unknown function (DUF1405)
WR51_RS07705	COG2738	Putative neutral zinc metallopeptidase
WR51_RS07715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS07720	COG1694	Mazg nucleotide pyrophosphohydrolase
WR51_RS07740	COG0438	transferase activity, transferring glycosyl groups
WR51_RS07775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WR51_RS07775	COG1199	ATP-dependent helicase activity
WR51_RS07795	COG3935	DnaD domain protein
WR51_RS07800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WR51_RS07810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_RS07810	COG4499	WXG100 protein secretion system (Wss), protein YukC
WR51_RS07865	COG0116	Belongs to the methyltransferase superfamily
WR51_RS07875	COG1199	ATP-dependent helicase activity
WR51_RS07880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WR51_RS07890	COG0024	Methionine aminopeptidase
WR51_RS07900	COG2233	PERMEase
WR51_RS07910	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR51_RS07920	COG0456	acetyltransferase
WR51_RS07970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR51_RS07985	COG3944	biosynthesis protein
WR51_RS07995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WR51_RS08010	COG1215	transferase activity, transferring glycosyl groups
WR51_RS08015	COG0438	transferase activity, transferring glycosyl groups
WR51_RS08050	COG0328	RNA-DNA hybrid ribonuclease activity
WR51_RS08085	COG3403	YqcI/YcgG family
WR51_RS08090	COG1280	lysine exporter protein (LysE YggA)
WR51_RS08110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_RS08115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR51_RS08125	COG0475	glutathione-regulated potassium exporter activity
WR51_RS08130	COG4978	Transcriptional regulator
WR51_RS08130	COG0789	Transcriptional regulator
WR51_RS08140	COG2323	membrane
WR51_RS08145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WR51_RS08155	COG2801	Transposase and inactivated derivatives
WR51_RS08215	COG1923	regulation of RNA biosynthetic process
WR51_RS08225	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WR51_RS08230	COG1360	Flagellar Motor Protein
WR51_RS08235	COG2201	protein-glutamate methylesterase activity
WR51_RS08240	COG2198	Histidine kinase
WR51_RS08240	COG0643	Histidine kinase
WR51_RS08245	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_RS08245	COG1776	CheC inhibitor of MCP methylation
WR51_RS08260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WR51_RS08280	COG1256	bacterial-type flagellum assembly
WR51_RS08285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WR51_RS08305	COG1815	bacterial-type flagellum-dependent cell motility
WR51_RS08310	COG1558	bacterial-type flagellum-dependent cell motility
WR51_RS08320	COG1766	The M ring may be actively involved in energy transduction
WR51_RS08325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_RS08335	COG1157	protein secretion by the type III secretion system
WR51_RS08355	COG1749	Flagellar hook protein flgE
WR51_RS08370	COG0835	chemotaxis
WR51_RS08370	COG0784	Response regulator, receiver
WR51_RS08385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WR51_RS08390	COG0741	lytic transglycosylase activity
WR51_RS08400	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_RS08405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WR51_RS08405	COG1776	CheC inhibitor of MCP methylation
WR51_RS08415	COG1338	Plays a role in the flagellum-specific transport system
WR51_RS08420	COG1987	bacterial-type flagellum assembly
WR51_RS08430	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WR51_RS08435	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WR51_RS08440	COG1419	protein localization to endoplasmic reticulum
WR51_RS08445	COG4786	Flagellar basal body rod
WR51_RS08450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR51_RS08455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WR51_RS08485	COG2329	Antibiotic biosynthesis monooxygenase
WR51_RS08510	COG0583	DNA-binding transcription factor activity
WR51_RS08515	COG3842	ATPase activity
WR51_RS08555	COG0406	alpha-ribazole phosphatase activity
WR51_RS08585	COG0367	asparagine synthase
WR51_RS08615	COG1802	Transcriptional regulator
WR51_RS08620	COG0697	spore germination
WR51_RS08630	COG0523	cobalamin synthesis protein
WR51_RS08635	COG0701	Predicted permease
WR51_RS08650	COG1757	Na H antiporter
WR51_RS08655	COG0789	Transcriptional regulator
WR51_RS08680	COG0534	Mate efflux family protein
WR51_RS08685	COG3340	Belongs to the peptidase S51 family
WR51_RS08705	COG0785	Cytochrome C biogenesis protein
WR51_RS08710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_RS08720	COG0457	Tetratricopeptide repeat
WR51_RS08740	COG2733	membrane
WR51_RS08775	COG1131	(ABC) transporter
WR51_RS08790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_RS08795	COG0528	UMP kinase activity
WR51_RS08805	COG1027	Aspartate ammonia-lyase
WR51_RS08810	COG0281	malic enzyme
WR51_RS08815	COG4191	Histidine kinase
WR51_RS08820	COG0784	Response regulator, receiver
WR51_RS08825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR51_RS08880	COG2814	Major facilitator Superfamily
WR51_RS08900	COG1695	Transcriptional regulator
WR51_RS08910	COG0477	Major facilitator Superfamily
WR51_RS08925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WR51_RS08930	COG2223	nitrite transmembrane transporter activity
WR51_RS08935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_RS08955	COG0733	neurotransmitter:sodium symporter activity
WR51_RS08965	COG5566	PFAM Mor transcription activator
WR51_RS08970	COG2323	membrane
WR51_RS08990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR51_RS09000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_RS09005	COG0028	Belongs to the TPP enzyme family
WR51_RS09025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WR51_RS09050	COG2814	Major facilitator Superfamily
WR51_RS09055	COG3384	dioxygenase
WR51_RS09065	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WR51_RS09070	COG3279	Response regulator of the LytR AlgR family
WR51_RS09075	COG0427	acetyl-CoA hydrolase
WR51_RS09110	COG4166	transmembrane transport
WR51_RS09140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS09160	COG1914	H( )-stimulated, divalent metal cation uptake system
WR51_RS09175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WR51_RS09185	COG0531	amino acid
WR51_RS09195	COG0083	homoserine kinase activity
WR51_RS09210	COG2309	aminopeptidase activity
WR51_RS09225	COG0456	acetyltransferase
WR51_RS09240	COG1309	transcriptional regulator
WR51_RS09245	COG2390	Transcriptional regulator
WR51_RS09255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS09260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WR51_RS09270	COG4846	Membrane protein involved in cytochrome C biogenesis
WR51_RS09290	COG0583	DNA-binding transcription factor activity
WR51_RS09305	COG0006	proline dipeptidase activity
WR51_RS09315	COG2132	Multicopper oxidase
WR51_RS09325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WR51_RS09345	COG1114	Component of the transport system for branched-chain amino acids
WR51_RS09355	COG1276	copper resistance
WR51_RS09355	COG2372	response to copper ion
WR51_RS09360	COG4549	nuclear export factor GLE1
WR51_RS09365	COG0697	spore germination
WR51_RS09370	COG0583	DNA-binding transcription factor activity
WR51_RS09375	COG1959	2 iron, 2 sulfur cluster binding
WR51_RS09380	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
WR51_RS09385	COG0778	Nitroreductase
WR51_RS09400	COG0628	permease
WR51_RS09410	COG1231	oxidoreductase activity
WR51_RS09415	COG0523	cobalamin synthesis protein
WR51_RS09425	COG0411	ABC transporter
WR51_RS09445	COG0583	DNA-binding transcription factor activity
WR51_RS09455	COG1942	4-Oxalocrotonate Tautomerase
WR51_RS09475	COG1271	oxidase subunit
WR51_RS09480	COG1294	oxidase, subunit
WR51_RS09485	COG4988	ABC transporter
WR51_RS09490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WR51_RS09500	COG1216	Glycosyl transferase, family 2
WR51_RS09540	COG1686	Belongs to the peptidase S11 family
WR51_RS09555	COG1388	LysM domain
WR51_RS09555	COG0791	NLP P60 protein
WR51_RS09565	COG1132	(ABC) transporter
WR51_RS09570	COG0745	RESPONSE REGULATOR receiver
WR51_RS09575	COG5002	protein histidine kinase activity
WR51_RS09585	COG0300	oxidoreductase activity
WR51_RS09590	COG4122	O-methyltransferase activity
WR51_RS09620	COG0460	homoserine dehydrogenase
WR51_RS09645	COG1316	TRANSCRIPTIONal
WR51_RS09655	COG0745	RESPONSE REGULATOR receiver
WR51_RS09660	COG5002	protein histidine kinase activity
WR51_RS09675	COG1285	pathogenesis
WR51_RS09680	COG1247	-acetyltransferase
WR51_RS09700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR51_RS09710	COG1082	Xylose isomerase domain protein TIM barrel
WR51_RS09720	COG2814	Major facilitator Superfamily
WR51_RS09725	COG1279	arginine transmembrane transporter activity
WR51_RS09730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS09740	COG1752	Esterase of the alpha-beta hydrolase superfamily
WR51_RS09775	COG0577	efflux transmembrane transporter activity
WR51_RS09780	COG2002	toxin-antitoxin pair type II binding
WR51_RS09785	COG1404	Belongs to the peptidase S8 family
WR51_RS09790	COG0640	Transcriptional regulator
WR51_RS09795	COG0667	Aldo Keto reductase
WR51_RS09825	COG0840	transmembrane signaling receptor activity
WR51_RS09840	COG3949	Membrane
WR51_RS09845	COG0783	Belongs to the Dps family
WR51_RS09860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR51_RS09870	COG1231	oxidoreductase activity
WR51_RS09875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS09880	COG4989	oxidoreductase activity
WR51_RS09885	COG0523	cobalamin synthesis protein
WR51_RS09890	COG0456	acetyltransferase
WR51_RS09895	COG0803	Belongs to the bacterial solute-binding protein 9 family
WR51_RS09900	COG0702	epimerase
WR51_RS09910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WR51_RS09920	COG4166	transmembrane transport
WR51_RS09945	COG5337	Spore coat protein CotH
WR51_RS09950	COG1051	belongs to the nudix hydrolase family
WR51_RS09955	COG0586	Pfam SNARE associated Golgi protein
WR51_RS09960	COG2244	polysaccharide biosynthetic process
WR51_RS09970	COG0701	Predicted permease
WR51_RS09975	COG3689	TIGRFAM TIGR03943 family protein
WR51_RS09980	COG1607	acyl-coa hydrolase
WR51_RS09985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_RS10000	COG0702	epimerase
WR51_RS10005	COG2839	Protein conserved in bacteria
WR51_RS10010	COG1253	flavin adenine dinucleotide binding
WR51_RS10025	COG1114	Component of the transport system for branched-chain amino acids
WR51_RS10030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WR51_RS10045	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_RS10055	COG1876	peptidase activity
WR51_RS10070	COG2211	Major facilitator Superfamily
WR51_RS10075	COG2801	Transposase and inactivated derivatives
WR51_RS10095	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_RS10105	COG0561	phosphatase activity
WR51_RS10110	COG1846	Transcriptional regulator
WR51_RS10115	COG2814	Major facilitator Superfamily
WR51_RS10125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR51_RS10130	COG4106	trans-aconitate 2-methyltransferase activity
WR51_RS10145	COG1819	glycosyl
WR51_RS10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS10155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS10185	COG0456	acetyltransferase
WR51_RS10235	COG3874	Sporulation protein YtfJ
WR51_RS10260	COG2226	methyltransferase
WR51_RS10280	COG1082	Xylose isomerase domain protein TIM barrel
WR51_RS10285	COG0346	lactoylglutathione lyase activity
WR51_RS10295	COG0604	alcohol dehydrogenase
WR51_RS10300	COG1595	DNA-templated transcription, initiation
WR51_RS10315	COG0426	domain, Protein
WR51_RS10315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WR51_RS10325	COG0386	Belongs to the glutathione peroxidase family
WR51_RS10330	COG1305	Transglutaminase-like
WR51_RS10335	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
WR51_RS10340	COG0714	Associated with various cellular activities
WR51_RS10345	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
WR51_RS10350	COG1140	nitrate reductase beta subunit
WR51_RS10355	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
WR51_RS10360	COG2181	nitrate reductase activity
WR51_RS10365	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_RS10370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WR51_RS10375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_RS10380	COG0303	'Molybdopterin
WR51_RS10385	COG0314	molybdopterin synthase activity
WR51_RS10395	COG2223	nitrite transmembrane transporter activity
WR51_RS10410	COG1648	precorrin-2 dehydrogenase activity
WR51_RS10420	COG1587	Uroporphyrinogen-III synthase
WR51_RS10420	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WR51_RS10425	COG2146	nitrite reductase [NAD(P)H] activity
WR51_RS10430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WR51_RS10435	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
WR51_RS10470	COG2359	stage V sporulation protein S
WR51_RS10490	COG1418	mRNA catabolic process
WR51_RS10495	COG0488	(ABC) transporter
WR51_RS10510	COG0629	single-stranded DNA binding
WR51_RS10520	COG1413	lyase activity
WR51_RS10535	COG2521	methyltransferase
WR51_RS10535	COG2136	Putative SAM-dependent methyltransferase
WR51_RS10540	COG0018	arginyl-trna synthetase
WR51_RS10580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WR51_RS10585	COG0017	Asparaginyl-tRNA synthetase
WR51_RS10605	COG1674	ftsk spoiiie
WR51_RS10710	COG0733	neurotransmitter:sodium symporter activity
WR51_RS10735	COG2610	gluconate transmembrane transporter activity
WR51_RS10745	COG1794	racemase activity, acting on amino acids and derivatives
WR51_RS10755	COG0456	acetyltransferase
WR51_RS10765	COG3655	Transcriptional regulator
WR51_RS10770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WR51_RS10780	COG1131	(ABC) transporter
WR51_RS10785	COG4473	ABC transporter
WR51_RS10795	COG0546	phosphoglycolate phosphatase activity
WR51_RS10805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_RS10820	COG0768	penicillin binding
WR51_RS10830	COG0204	Acyl-transferase
WR51_RS10835	COG1272	protein, Hemolysin III
WR51_RS10845	COG0805	protein transport
WR51_RS10855	COG1307	EDD domain protein, DegV family
WR51_RS10865	COG1999	signal sequence binding
WR51_RS10870	COG0071	Belongs to the small heat shock protein (HSP20) family
WR51_RS10875	COG0367	asparagine synthase
WR51_RS10890	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_RS10895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS10900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WR51_RS10920	COG1335	isochorismatase
WR51_RS10930	COG0668	transmembrane transport
WR51_RS10935	COG4585	Histidine kinase
WR51_RS10935	COG2203	Gaf domain
WR51_RS10940	COG2197	response regulator
WR51_RS10945	COG1737	Transcriptional regulator
WR51_RS10950	COG0384	phenazine biosynthesis protein PhzF
WR51_RS10955	COG1064	alcohol dehydrogenase
WR51_RS10970	COG1070	Carbohydrate kinase
WR51_RS10980	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WR51_RS11015	COG0517	IMP dehydrogenase activity
WR51_RS11015	COG1125	glycine betaine transport
WR51_RS11020	COG1174	glycine betaine transport
WR51_RS11055	COG1253	flavin adenine dinucleotide binding
WR51_RS11060	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS11065	COG5506	Protein of unknown function (DUF1694)
WR51_RS11080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR51_RS11085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
WR51_RS11090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
WR51_RS11095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR51_RS11100	COG0456	acetyltransferase
WR51_RS11105	COG3829	transcription factor binding
WR51_RS11110	COG1509	lysine 2,3-aminomutase activity
WR51_RS11140	COG3064	Membrane
WR51_RS11140	COG4991	sh3 domain protein
WR51_RS11140	COG0515	serine threonine protein kinase
WR51_RS11150	COG0671	phosphoesterase, PA-phosphatase related
WR51_RS11155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WR51_RS11160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_RS11250	COG0300	oxidoreductase activity
WR51_RS11270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_RS11270	COG4499	WXG100 protein secretion system (Wss), protein YukC
WR51_RS11280	COG2814	Major facilitator Superfamily
WR51_RS11285	COG4841	protein insertion into membrane
WR51_RS11290	COG0372	Belongs to the citrate synthase family
WR51_RS11295	COG2079	MmgE PrpD family protein
WR51_RS11300	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WR51_RS11305	COG1960	acyl-CoA dehydrogenase activity
WR51_RS11310	COG2084	Dehydrogenase
WR51_RS11320	COG1280	lysine exporter protein (LysE YggA)
WR51_RS11325	COG1024	Enoyl-CoA hydratase
WR51_RS11340	COG0420	3'-5' exonuclease activity
WR51_RS11345	COG0419	ATPase involved in DNA repair
WR51_RS11365	COG2223	nitrite transmembrane transporter activity
WR51_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS11375	COG1169	isochorismate synthase
WR51_RS11380	COG1021	2,3-dihydroxybenzoate-AMP ligase
WR51_RS11385	COG1535	isochorismatase
WR51_RS11385	COG3433	isochorismatase activity
WR51_RS11390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WR51_RS11395	COG3251	PFAM MbtH domain protein
WR51_RS11400	COG2814	Major facilitator Superfamily
WR51_RS11415	COG0776	regulation of translation
WR51_RS11425	COG2318	DinB family
WR51_RS11435	COG1115	amino acid carrier protein
WR51_RS11455	COG1187	pseudouridine synthase activity
WR51_RS11460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WR51_RS11465	COG1136	(ABC) transporter
WR51_RS11475	COG0596	Alpha beta hydrolase
WR51_RS11480	COG0028	Belongs to the TPP enzyme family
WR51_RS11515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_RS11530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS11555	COG2801	Transposase and inactivated derivatives
WR51_RS11575	COG1247	-acetyltransferase
WR51_RS11600	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
WR51_RS11610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS11640	COG0583	DNA-binding transcription factor activity
WR51_RS11645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WR51_RS11665	COG0583	DNA-binding transcription factor activity
WR51_RS11670	COG2258	MOSC domain
WR51_RS11685	COG1132	(ABC) transporter
WR51_RS11690	COG1132	(ABC) transporter
WR51_RS11705	COG0582	viral genome integration into host DNA
WR51_RS11720	COG1396	sequence-specific DNA binding
WR51_RS11750	COG2002	toxin-antitoxin pair type II binding
WR51_RS11780	COG0582	viral genome integration into host DNA
WR51_RS11820	COG4626	Terminase
WR51_RS11820	COG1802	Transcriptional regulator
WR51_RS11830	COG0740	serine-type endopeptidase activity
WR51_RS11900	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_RS11930	COG1396	sequence-specific DNA binding
WR51_RS11965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR51_RS11970	COG1595	DNA-templated transcription, initiation
WR51_RS11995	COG1649	PFAM Uncharacterised BCR, COG1649
WR51_RS12020	COG2971	BadF BadG BcrA BcrD
WR51_RS12030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
WR51_RS12040	COG1846	Transcriptional regulator
WR51_RS12055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS12070	COG1309	transcriptional regulator
WR51_RS12160	COG3615	Tellurite resistance protein tehB
WR51_RS12160	COG0500	methyltransferase
WR51_RS12170	COG2226	methyltransferase
WR51_RS12175	COG3961	Belongs to the TPP enzyme family
WR51_RS12180	COG1846	Transcriptional regulator
WR51_RS12230	COG2195	Cleaves the N-terminal amino acid of tripeptides
WR51_RS12260	COG2002	toxin-antitoxin pair type II binding
WR51_RS12270	COG0730	response to heat
WR51_RS12275	COG0110	maltose O-acetyltransferase activity
WR51_RS12280	COG1686	Belongs to the peptidase S11 family
WR51_RS12295	COG2814	Major facilitator Superfamily
WR51_RS12330	COG1115	amino acid carrier protein
WR51_RS12335	COG2066	Belongs to the glutaminase family
WR51_RS12340	COG4191	Histidine kinase
WR51_RS12345	COG0784	Response regulator, receiver
WR51_RS12350	COG0697	spore germination
WR51_RS12355	COG0531	amino acid
WR51_RS12365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_RS12370	COG0531	amino acid
WR51_RS12375	COG0322	excinuclease ABC activity
WR51_RS12385	COG2207	Transcriptional regulator
WR51_RS12410	COG5002	protein histidine kinase activity
WR51_RS12455	COG0741	lytic transglycosylase activity
WR51_RS12460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS12475	COG1396	sequence-specific DNA binding
WR51_RS12495	COG1309	transcriptional regulator
WR51_RS12500	COG0367	asparagine synthase
WR51_RS12505	COG4585	Histidine kinase
WR51_RS12515	COG1404	Belongs to the peptidase S8 family
WR51_RS12560	COG0768	penicillin binding
WR51_RS12565	COG1595	DNA-templated transcription, initiation
WR51_RS12575	COG0768	penicillin binding
WR51_RS12580	COG0768	penicillin binding
WR51_RS12590	COG1408	metallophosphoesterase
WR51_RS12600	COG1131	(ABC) transporter
WR51_RS12610	COG1309	transcriptional regulator
WR51_RS12625	COG1960	acyl-CoA dehydrogenase activity
WR51_RS12630	COG0439	Biotin carboxylase
WR51_RS12635	COG0511	ligase activity, forming carbon-carbon bonds
WR51_RS12640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WR51_RS12645	COG1024	Enoyl-CoA hydratase
WR51_RS12650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WR51_RS12655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR51_RS12680	COG1686	Belongs to the peptidase S11 family
WR51_RS12705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WR51_RS12720	COG3227	Zinc metalloprotease (Elastase)
WR51_RS12725	COG2207	Transcriptional regulator
WR51_RS12755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WR51_RS12765	COG2814	Major facilitator Superfamily
WR51_RS12770	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS12775	COG1733	regulation of RNA biosynthetic process
WR51_RS12820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS12830	COG2368	4-hydroxyphenylacetate
WR51_RS12845	COG1063	alcohol dehydrogenase
WR51_RS12855	COG2323	membrane
WR51_RS12860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WR51_RS12865	COG0693	protein deglycase activity
WR51_RS12875	COG3386	PFAM SMP-30 Gluconolaconase
WR51_RS12880	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
WR51_RS12885	COG3773	Cell wall hydrolase
WR51_RS12895	COG0745	RESPONSE REGULATOR receiver
WR51_RS12900	COG2205	protein histidine kinase activity
WR51_RS12910	COG0488	(ABC) transporter
WR51_RS12925	COG1136	(ABC) transporter
WR51_RS12930	COG0577	efflux transmembrane transporter activity
WR51_RS12950	COG0460	homoserine dehydrogenase
WR51_RS12955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS12965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
WR51_RS12990	COG0582	viral genome integration into host DNA
WR51_RS13015	COG1396	sequence-specific DNA binding
WR51_RS13035	COG1484	DNA-dependent DNA replication
WR51_RS13055	COG2002	toxin-antitoxin pair type II binding
WR51_RS13120	COG0582	viral genome integration into host DNA
WR51_RS13150	COG5484	DNA packaging
WR51_RS13165	COG0740	serine-type endopeptidase activity
WR51_RS13285	COG2124	cytochrome p450
WR51_RS13320	COG0561	phosphatase activity
WR51_RS13325	COG5002	protein histidine kinase activity
WR51_RS13330	COG0768	penicillin binding
WR51_RS13340	COG1819	glycosyl
WR51_RS13345	COG1794	racemase activity, acting on amino acids and derivatives
WR51_RS13365	COG2205	protein histidine kinase activity
WR51_RS13415	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR51_RS13420	COG0604	alcohol dehydrogenase
WR51_RS13425	COG0671	phosphoesterase, PA-phosphatase related
WR51_RS13430	COG0768	penicillin binding
WR51_RS13440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_RS13485	COG2814	Major facilitator Superfamily
WR51_RS13500	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_RS13520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS13525	COG0697	spore germination
WR51_RS13560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_RS13570	COG2223	nitrite transmembrane transporter activity
WR51_RS13585	COG0592	DNA-directed DNA polymerase activity
WR51_RS13620	COG3878	Protein conserved in bacteria
WR51_RS13645	COG4667	esterase of the alpha-beta hydrolase superfamily
WR51_RS13685	COG0322	excinuclease ABC activity
WR51_RS13725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_RS13750	COG1011	Hydrolase
WR51_RS13755	COG0745	RESPONSE REGULATOR receiver
WR51_RS13760	COG5002	protein histidine kinase activity
WR51_RS13770	COG3813	Protein conserved in bacteria
WR51_RS13775	COG1522	sequence-specific DNA binding
WR51_RS13790	COG1136	(ABC) transporter
WR51_RS13795	COG0577	efflux transmembrane transporter activity
WR51_RS13805	COG0657	acetylesterase activity
WR51_RS13810	COG0076	glutamate decarboxylase activity
WR51_RS13825	COG1523	belongs to the glycosyl hydrolase 13 family
WR51_RS13830	COG3227	Zinc metalloprotease (Elastase)
WR51_RS13835	COG0737	Belongs to the 5'-nucleotidase family
WR51_RS13850	COG0201	protein transport
WR51_RS13865	COG0697	spore germination
WR51_RS13870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS13880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WR51_RS13910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS13925	COG2959	enzyme of heme biosynthesis
WR51_RS13965	COG1309	transcriptional regulator
WR51_RS13995	COG3284	Transcriptional regulator
WR51_RS14010	COG1349	DNA-binding transcription factor activity
WR51_RS14025	COG1959	2 iron, 2 sulfur cluster binding
WR51_RS14040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR51_RS14045	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR51_RS14050	COG0022	dehydrogenase e1 component
WR51_RS14055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR51_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS14070	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR51_RS14070	COG0456	acetyltransferase
WR51_RS14110	COG4176	ABC-type proline glycine betaine transport system permease component
WR51_RS14115	COG4175	Glycine betaine
WR51_RS14115	COG0517	IMP dehydrogenase activity
WR51_RS14145	COG2153	protein acetylation
WR51_RS14150	COG3397	chitin binding
WR51_RS14155	COG1819	glycosyl
WR51_RS14180	COG2315	Protein conserved in bacteria
WR51_RS14225	COG0456	acetyltransferase
WR51_RS14230	COG3973	AAA domain
WR51_RS14240	COG0514	ATP-dependent DNA helicase (RecQ)
WR51_RS14260	COG2801	Transposase and inactivated derivatives
WR51_RS14275	COG4637	Psort location Cytoplasmic, score
WR51_RS14295	COG3397	chitin binding
WR51_RS14310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WR51_RS14315	COG1115	amino acid carrier protein
WR51_RS14320	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS14325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WR51_RS14335	COG3938	Belongs to the proline racemase family
WR51_RS14340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WR51_RS14380	COG0586	Pfam SNARE associated Golgi protein
WR51_RS14390	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
WR51_RS14395	COG4166	transmembrane transport
WR51_RS14405	COG4948	Mandelate Racemase Muconate Lactonizing
WR51_RS14420	COG0667	Aldo Keto reductase
WR51_RS14460	COG3850	Histidine kinase
WR51_RS14460	COG5002	protein histidine kinase activity
WR51_RS14465	COG0745	RESPONSE REGULATOR receiver
WR51_RS14505	COG1164	Oligoendopeptidase f
WR51_RS14510	COG1307	EDD domain protein, DegV family
WR51_RS14550	COG2814	Major facilitator Superfamily
WR51_RS14560	COG1664	Polymer-forming cytoskeletal
WR51_RS14565	COG0789	Transcriptional regulator
WR51_RS14570	COG4533	DNA binding
WR51_RS14575	COG0477	Major facilitator Superfamily
WR51_RS14575	COG2814	Major facilitator Superfamily
WR51_RS14600	COG2261	transglycosylase associated protein
WR51_RS14615	COG2226	methyltransferase
WR51_RS14650	COG0436	Aminotransferase
WR51_RS14655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WR51_RS14665	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
WR51_RS14680	COG1131	(ABC) transporter
WR51_RS14745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WR51_RS14750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_RS14755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_RS14795	COG2746	aminoglycoside 3-N-acetyltransferase activity
WR51_RS14805	COG0697	spore germination
WR51_RS14830	COG4912	Dna alkylation repair
WR51_RS14835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_RS14840	COG0346	lactoylglutathione lyase activity
WR51_RS14845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS14870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_RS14875	COG0861	Integral membrane protein TerC family
WR51_RS14880	COG1368	sulfuric ester hydrolase activity
WR51_RS14885	COG0488	(ABC) transporter
WR51_RS14890	COG1033	growth of symbiont in host cell
WR51_RS14890	COG2409	Drug exporters of the RND superfamily
WR51_RS14895	COG1309	transcriptional regulator
WR51_RS14900	COG1051	belongs to the nudix hydrolase family
WR51_RS14915	COG0287	Prephenate dehydrogenase
WR51_RS14930	COG1605	Chorismate mutase
WR51_RS14930	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR51_RS14975	COG1388	LysM domain
WR51_RS14975	COG3584	3D domain protein
WR51_RS14985	COG0277	FAD linked oxidase domain protein
WR51_RS15010	COG1879	ABC-type sugar transport system periplasmic component
WR51_RS15015	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR51_RS15020	COG1172	Belongs to the binding-protein-dependent transport system permease family
WR51_RS15030	COG2390	Transcriptional regulator
WR51_RS15035	COG1070	Carbohydrate kinase
WR51_RS15055	COG2329	Antibiotic biosynthesis monooxygenase
WR51_RS15070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS15085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_RS15090	COG4187	Peptidase family M20/M25/M40
WR51_RS15095	COG1414	Transcriptional regulator
WR51_RS15100	COG0833	amino acid
WR51_RS15115	COG3239	Fatty acid desaturase
WR51_RS15125	COG2720	vancomycin resistance protein
WR51_RS15130	COG1785	Belongs to the alkaline phosphatase family
WR51_RS15140	COG3655	Transcriptional regulator
WR51_RS15165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS15170	COG0346	lactoylglutathione lyase activity
WR51_RS15195	COG0714	Associated with various cellular activities
WR51_RS15215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WR51_RS15220	COG0753	catalase activity
WR51_RS15255	COG0778	Nitroreductase
WR51_RS15260	COG1846	Transcriptional regulator
WR51_RS15295	COG1725	Transcriptional regulator
WR51_RS15300	COG4282	regulation of fungal-type cell wall biogenesis
WR51_RS15325	COG0456	acetyltransferase
WR51_RS15340	COG0697	spore germination
WR51_RS15345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS15385	COG0730	response to heat
WR51_RS15395	COG0833	amino acid
WR51_RS15405	COG4335	DNA alkylation repair
WR51_RS15435	COG0768	penicillin binding
WR51_RS15465	COG1984	allophanate hydrolase subunit 2
WR51_RS15470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
WR51_RS15475	COG1414	Transcriptional regulator
WR51_RS15490	COG3142	Participates in the control of copper homeostasis
WR51_RS15495	COG0640	Transcriptional regulator
WR51_RS15505	COG1960	acyl-CoA dehydrogenase activity
WR51_RS15520	COG3314	Sporulation integral membrane protein YlbJ
WR51_RS15540	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
WR51_RS15565	COG3848	Pyruvate phosphate dikinase
WR51_RS15565	COG0574	Belongs to the PEP-utilizing enzyme family
WR51_RS15570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS15590	COG1063	alcohol dehydrogenase
WR51_RS15600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR51_RS15610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WR51_RS15625	COG0737	Belongs to the 5'-nucleotidase family
WR51_RS15630	COG2267	carboxylic ester hydrolase activity
WR51_RS15635	COG1335	isochorismatase
WR51_RS15655	COG0583	DNA-binding transcription factor activity
WR51_RS15660	COG1846	Transcriptional regulator
WR51_RS15665	COG0598	Magnesium transport protein CorA
WR51_RS15705	COG0415	Belongs to the DNA photolyase family
WR51_RS15720	COG0288	reversible hydration of carbon dioxide
WR51_RS15730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WR51_RS15735	COG5609	conserved protein (DUF2294)
WR51_RS15745	COG0456	acetyltransferase
WR51_RS15750	COG1575	Belongs to the MenA family. Type 1 subfamily
WR51_RS15770	COG0798	PFAM Bile acid sodium symporter
WR51_RS15775	COG0346	lactoylglutathione lyase activity
WR51_RS15780	COG0640	Transcriptional regulator
WR51_RS15795	COG2169	Transcriptional regulator
WR51_RS15810	COG1309	transcriptional regulator
WR51_RS15815	COG2814	Major facilitator Superfamily
WR51_RS15820	COG1309	transcriptional regulator
WR51_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS15830	COG1522	sequence-specific DNA binding
WR51_RS15845	COG0346	lactoylglutathione lyase activity
WR51_RS15875	COG0814	amino acid
WR51_RS15880	COG0583	DNA-binding transcription factor activity
WR51_RS15910	COG1131	(ABC) transporter
WR51_RS15915	COG1725	Transcriptional regulator
WR51_RS15955	COG0745	RESPONSE REGULATOR receiver
WR51_RS15960	COG5002	protein histidine kinase activity
WR51_RS15960	COG3850	Histidine kinase
WR51_RS16000	COG1136	(ABC) transporter
WR51_RS16035	COG2814	Major facilitator Superfamily
WR51_RS16055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
WR51_RS16065	COG1690	Belongs to the RtcB family
WR51_RS16075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
WR51_RS16095	COG0577	efflux transmembrane transporter activity
WR51_RS16115	COG3850	Histidine kinase
WR51_RS16115	COG5002	protein histidine kinase activity
WR51_RS16125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS16135	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR51_RS16155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WR51_RS16175	COG0662	Cupin 2, conserved barrel domain protein
WR51_RS16180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS16180	COG2207	Transcriptional regulator
WR51_RS16200	COG3409	Peptidoglycan-binding domain 1 protein
WR51_RS16200	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_RS16210	COG2814	Major facilitator Superfamily
WR51_RS16230	COG1876	peptidase activity
WR51_RS16235	COG2843	Capsule synthesis protein
WR51_RS16245	COG0477	Major facilitator Superfamily
WR51_RS16260	COG1846	Transcriptional regulator
WR51_RS16265	COG2814	Major facilitator Superfamily
WR51_RS16275	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WR51_RS16280	COG1131	(ABC) transporter
WR51_RS16300	COG2076	Multidrug Resistance protein
WR51_RS16305	COG1309	transcriptional regulator
WR51_RS16325	COG2031	fatty acid transporter
WR51_RS16335	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR51_RS16370	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
WR51_RS16390	COG1288	antiporter activity
WR51_RS16395	COG2356	endonuclease I
WR51_RS16425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WR51_RS16445	COG1733	regulation of RNA biosynthetic process
WR51_RS16450	COG0778	Nitroreductase
WR51_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS16490	COG1131	(ABC) transporter
WR51_RS16520	COG1011	Hydrolase
WR51_RS16530	COG2365	Tyrosine phosphatase family
WR51_RS16555	COG0346	lactoylglutathione lyase activity
WR51_RS16560	COG1940	carbohydrate kinase activity
WR51_RS16570	COG0110	maltose O-acetyltransferase activity
WR51_RS16585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS16600	COG0628	permease
WR51_RS16620	COG0500	methyltransferase
WR51_RS16630	COG0477	Major facilitator Superfamily
WR51_RS16670	COG1253	flavin adenine dinucleotide binding
WR51_RS16675	COG0789	Transcriptional regulator
WR51_RS16685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR51_RS16710	COG0697	spore germination
WR51_RS16720	COG1357	PFAM Pentapeptide repeats (8 copies)
WR51_RS16725	COG3813	Protein conserved in bacteria
WR51_RS16730	COG2706	6-phosphogluconolactonase activity
WR51_RS16735	COG1070	Carbohydrate kinase
WR51_RS16750	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
WR51_RS16755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WR51_RS16760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WR51_RS16765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
WR51_RS16790	COG0814	amino acid
WR51_RS16815	COG2188	Transcriptional regulator
WR51_RS16820	COG0673	inositol 2-dehydrogenase activity
WR51_RS16840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS16860	COG0384	phenazine biosynthesis protein PhzF
WR51_RS16875	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_RS16880	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR51_RS16885	COG1733	regulation of RNA biosynthetic process
WR51_RS16890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WR51_RS16905	COG2801	Transposase and inactivated derivatives
WR51_RS16915	COG0726	polysaccharide deacetylase
WR51_RS16925	COG1191	sigma factor activity
WR51_RS16955	COG1280	lysine exporter protein (LysE YggA)
WR51_RS17000	COG1151	hydroxylamine reductase activity
WR51_RS17010	COG3409	Peptidoglycan-binding domain 1 protein
WR51_RS17010	COG3757	hydrolase, family 25
WR51_RS17045	COG2072	flavoprotein involved in K transport
WR51_RS17080	COG0604	alcohol dehydrogenase
WR51_RS17085	COG1113	amino acid transport
WR51_RS17090	COG2814	Major facilitator Superfamily
WR51_RS17120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
WR51_RS17125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR51_RS17140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS17145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS17150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS17155	COG3739	integral membrane protein
WR51_RS17175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS17190	COG0583	DNA-binding transcription factor activity
WR51_RS17210	COG1193	negative regulation of DNA recombination
WR51_RS17225	COG2162	N-hydroxyarylamine O-acetyltransferase activity
WR51_RS17230	COG1164	Oligoendopeptidase f
WR51_RS17260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
WR51_RS17285	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_RS17325	COG0640	Transcriptional regulator
WR51_RS17330	COG0604	alcohol dehydrogenase
WR51_RS17340	COG0457	Tetratricopeptide repeat
WR51_RS17350	COG2808	Putative FMN-binding domain
WR51_RS17355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR51_RS17365	COG0277	FAD linked oxidase domain protein
WR51_RS17380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS17380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_RS17385	COG1252	NADH dehydrogenase
WR51_RS17400	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_RS17435	COG0823	Involved in the tonB-independent uptake of proteins
WR51_RS17440	COG3397	chitin binding
WR51_RS17450	COG0697	spore germination
WR51_RS17470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR51_RS17480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WR51_RS17495	COG0457	Tetratricopeptide repeat
WR51_RS17520	COG1404	Belongs to the peptidase S8 family
WR51_RS17545	COG5001	Diguanylate cyclase
WR51_RS17545	COG3300	MHYT domain
WR51_RS17550	COG0488	(ABC) transporter
WR51_RS17555	COG1309	transcriptional regulator
WR51_RS17570	COG1876	peptidase activity
WR51_RS17595	COG3852	Histidine kinase
WR51_RS17605	COG1285	pathogenesis
WR51_RS17615	COG2514	catechol 2,3-dioxygenase activity
WR51_RS17620	COG2720	vancomycin resistance protein
WR51_RS17655	COG0716	FMN binding
WR51_RS17665	COG1051	belongs to the nudix hydrolase family
WR51_RS17685	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS17695	COG0165	Argininosuccinate lyase
WR51_RS17710	COG4145	pantothenate transmembrane transporter activity
WR51_RS17720	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS17725	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS17735	COG1657	PFAM Prenyltransferase squalene oxidase
WR51_RS17740	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
WR51_RS17745	COG2962	Rard protein
WR51_RS17750	COG3326	Membrane
WR51_RS17765	COG0489	protein tyrosine kinase activity
WR51_RS17775	COG0314	molybdopterin synthase activity
WR51_RS17780	COG0303	'Molybdopterin
WR51_RS17785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_RS17790	COG2116	formate transmembrane transporter activity
WR51_RS17800	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WR51_RS17805	COG5609	conserved protein (DUF2294)
WR51_RS17810	COG2427	Protein of unknown function (DUF1641)
WR51_RS17815	COG3383	formate dehydrogenase (NAD+) activity
WR51_RS17820	COG0697	spore germination
WR51_RS17835	COG0531	amino acid
WR51_RS17870	COG2226	methyltransferase
WR51_RS17875	COG4166	transmembrane transport
WR51_RS17885	COG2801	Transposase and inactivated derivatives
WR51_RS17890	COG4166	transmembrane transport
WR51_RS17895	COG4166	transmembrane transport
WR51_RS17900	COG1316	TRANSCRIPTIONal
WR51_RS17910	COG1595	DNA-templated transcription, initiation
WR51_RS17920	COG1131	(ABC) transporter
WR51_RS17940	COG0673	inositol 2-dehydrogenase activity
WR51_RS17945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR51_RS17950	COG0187	DNA topoisomerase II activity
WR51_RS17955	COG1832	CoA-binding protein
WR51_RS17960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_RS17965	COG0745	RESPONSE REGULATOR receiver
WR51_RS17985	COG4841	protein insertion into membrane
WR51_RS17990	COG0824	Thioesterase
WR51_RS18015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_RS18025	COG2274	protein secretion by the type I secretion system
WR51_RS18030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
WR51_RS18060	COG2211	Major facilitator Superfamily
WR51_RS18070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WR51_RS18085	COG0183	Belongs to the thiolase family
WR51_RS18090	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_RS18095	COG1268	BioY protein
WR51_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_RS18110	COG5002	protein histidine kinase activity
WR51_RS18125	COG1136	(ABC) transporter
WR51_RS18140	COG1131	(ABC) transporter
WR51_RS18230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS18240	COG5002	protein histidine kinase activity
WR51_RS18245	COG0400	carboxylic ester hydrolase activity
WR51_RS18250	COG0346	lactoylglutathione lyase activity
WR51_RS18255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WR51_RS18260	COG0069	glutamate synthase activity
WR51_RS18265	COG1902	pentaerythritol trinitrate reductase activity
WR51_RS18270	COG1329	Transcriptional regulator
WR51_RS18275	COG0010	Belongs to the arginase family
WR51_RS18300	COG2226	methyltransferase
WR51_RS18325	COG4846	Membrane protein involved in cytochrome C biogenesis
WR51_RS18330	COG0785	Cytochrome C biogenesis protein
WR51_RS18340	COG1473	amidohydrolase
WR51_RS18350	COG1131	(ABC) transporter
WR51_RS18365	COG0583	DNA-binding transcription factor activity
WR51_RS18375	COG1346	cytolysis
WR51_RS18390	COG0730	response to heat
WR51_RS18415	COG1132	(ABC) transporter
WR51_RS18420	COG1132	(ABC) transporter
WR51_RS18455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_RS18460	COG0737	Belongs to the 5'-nucleotidase family
WR51_RS18470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WR51_RS18490	COG1695	Transcriptional regulator
WR51_RS18500	COG1388	LysM domain
WR51_RS18500	COG3409	Peptidoglycan-binding domain 1 protein
WR51_RS18500	COG5632	N-Acetylmuramoyl-L-alanine amidase
WR51_RS18535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WR51_RS18540	COG0174	glutamine synthetase
WR51_RS18545	COG0789	Transcriptional regulator
WR51_RS18550	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
WR51_RS18555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WR51_RS18560	COG2860	membrane
WR51_RS18570	COG0464	growth
WR51_RS18600	COG1388	LysM domain
WR51_RS18600	COG3584	3D domain protein
WR51_RS18605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WR51_RS18605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WR51_RS18605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_RS18610	COG1105	Belongs to the carbohydrate kinase PfkB family
WR51_RS18615	COG1349	DNA-binding transcription factor activity
WR51_RS18620	COG1979	alcohol dehydrogenase
WR51_RS18625	COG2322	membrane
WR51_RS18640	COG1113	amino acid transport
WR51_RS18650	COG1408	metallophosphoesterase
WR51_RS18655	COG2116	formate transmembrane transporter activity
WR51_RS18670	COG2217	Heavy metal translocating P-type atpase
WR51_RS18675	COG2608	mercury ion transmembrane transporter activity
WR51_RS18680	COG2801	Transposase and inactivated derivatives
WR51_RS18690	COG1937	Protein conserved in bacteria
WR51_RS18700	COG2819	hydrolase of the alpha beta superfamily
WR51_RS18705	COG1120	ATPase activity
WR51_RS18710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS18715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS18720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS18725	COG0708	Exodeoxyribonuclease III
WR51_RS18730	COG2169	Transcriptional regulator
WR51_RS18735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WR51_RS18740	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
WR51_RS18750	COG2364	Membrane
WR51_RS18765	COG2267	carboxylic ester hydrolase activity
WR51_RS18770	COG3300	MHYT domain
WR51_RS18770	COG5001	Diguanylate cyclase
WR51_RS18790	COG1086	Polysaccharide biosynthesis protein
WR51_RS18805	COG1346	cytolysis
WR51_RS18815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WR51_RS18825	COG2188	Transcriptional regulator
WR51_RS18830	COG2723	6-phospho-beta-galactosidase activity
WR51_RS18840	COG1404	Belongs to the peptidase S8 family
WR51_RS18845	COG3773	Cell wall hydrolase
WR51_RS18855	COG1368	sulfuric ester hydrolase activity
WR51_RS18860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
WR51_RS18885	COG4550	Control of competence regulator ComK, YlbF/YmcA
WR51_RS18895	COG1013	pyruvate-flavodoxin oxidoreductase activity
WR51_RS18900	COG0674	pyruvate-flavodoxin oxidoreductase activity
WR51_RS18900	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WR51_RS18910	COG2359	stage V sporulation protein S
WR51_RS18915	COG1692	metallophosphoesterase
WR51_RS18940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WR51_RS18945	COG1426	Protein conserved in bacteria
WR51_RS18960	COG0300	oxidoreductase activity
WR51_RS18965	COG0612	Peptidase, M16
WR51_RS18970	COG0612	Peptidase, M16
WR51_RS18975	COG1079	Belongs to the binding-protein-dependent transport system permease family
WR51_RS18980	COG4603	Belongs to the binding-protein-dependent transport system permease family
WR51_RS18985	COG3845	ABC transporter
WR51_RS18990	COG1744	ABC transporter substrate-binding protein PnrA-like
WR51_RS18995	COG2188	Transcriptional regulator
WR51_RS19015	COG0740	serine-type endopeptidase activity
WR51_RS19020	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR51_RS19030	COG0527	aspartate kinase activity
WR51_RS19035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WR51_RS19040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR51_RS19055	COG5444	nuclease activity
WR51_RS19065	COG0582	viral genome integration into host DNA
WR51_RS19115	COG0305	Participates in initiation and elongation during chromosome replication
WR51_RS19170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR51_RS19175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WR51_RS19180	COG1873	PFAM PRC-barrel domain
WR51_RS19185	COG0612	Peptidase, M16
WR51_RS19190	COG0726	polysaccharide deacetylase
WR51_RS19205	COG0196	riboflavin kinase activity
WR51_RS19215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WR51_RS19220	COG1550	Protein conserved in bacteria
WR51_RS19230	COG1358	cellular component organization or biogenesis
WR51_RS19235	COG2740	Nucleic-acid-binding protein implicated in transcription termination
WR51_RS19240	COG0195	Participates in both transcription termination and antitermination
WR51_RS19260	COG0750	zinc metalloprotease
WR51_RS19270	COG4589	Belongs to the CDS family
WR51_RS19315	COG4974	Belongs to the 'phage' integrase family
WR51_RS19325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
WR51_RS19330	COG0758	DNA mediated transformation
WR51_RS19335	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
WR51_RS19375	COG1837	Belongs to the UPF0109 family
WR51_RS19385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WR51_RS19395	COG0552	protein localization to endoplasmic reticulum
WR51_RS19400	COG1196	nuclear chromosome segregation
WR51_RS19410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WR51_RS19415	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS19420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
WR51_RS19435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WR51_RS19440	COG1461	Dihydroxyacetone kinase
WR51_RS19445	COG1302	Protein conserved in bacteria
WR51_RS19460	COG1564	THIamine pyrophosphokinase
WR51_RS19465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WR51_RS19475	COG0515	serine threonine protein kinase
WR51_RS19475	COG2815	serine threonine protein kinase
WR51_RS19480	COG0631	protein serine/threonine phosphatase activity
WR51_RS19490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WR51_RS19490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WR51_RS19505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WR51_RS19510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WR51_RS19530	COG1561	YicC-like family, N-terminal region
WR51_RS19535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
WR51_RS19550	COG0006	proline dipeptidase activity
WR51_RS19570	COG3069	C4-dicarboxylate transmembrane transporter activity
WR51_RS19635	COG0564	pseudouridine synthase activity
WR51_RS19655	COG3599	regulation of cell shape
WR51_RS19660	COG2302	S4 RNA-binding domain
WR51_RS19665	COG0762	integral membrane protein
WR51_RS19675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WR51_RS19685	COG1873	PFAM PRC-barrel domain
WR51_RS19690	COG1191	sigma factor activity
WR51_RS19695	COG1191	sigma factor activity
WR51_RS19705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WR51_RS19710	COG0849	cell division
WR51_RS19730	COG0772	Belongs to the SEDS family
WR51_RS19750	COG0768	penicillin binding
WR51_RS19755	COG0768	penicillin binding
WR51_RS19775	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WR51_RS19790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WR51_RS19795	COG1399	metal-binding, possibly nucleic acid-binding protein
WR51_RS19805	COG3480	Lon protease (S16) C-terminal proteolytic domain
WR51_RS19810	COG1752	Esterase of the alpha-beta hydrolase superfamily
WR51_RS19815	COG3314	Sporulation integral membrane protein YlbJ
WR51_RS19825	COG0742	ribosomal rna small subunit methyltransferase
WR51_RS19840	COG3679	Belongs to the UPF0342 family
WR51_RS19845	COG0406	alpha-ribazole phosphatase activity
WR51_RS19860	COG2340	Cysteine-rich secretory protein family
WR51_RS19875	COG3336	cytochrome c oxidase
WR51_RS19910	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
WR51_RS19915	COG0772	Belongs to the SEDS family
WR51_RS19925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WR51_RS19930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WR51_RS19940	COG4896	Protein conserved in bacteria
WR51_RS19955	COG1217	gtp-binding protein TYPA
WR51_RS19965	COG0483	inositol monophosphate 1-phosphatase activity
WR51_RS19985	COG1982	Orn Lys Arg decarboxylase major
WR51_RS20035	COG0022	dehydrogenase e1 component
WR51_RS20040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR51_RS20055	COG0561	phosphatase activity
WR51_RS20065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
WR51_RS20070	COG0569	domain protein
WR51_RS20090	COG0583	DNA-binding transcription factor activity
WR51_RS20095	COG0517	IMP dehydrogenase activity
WR51_RS20105	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
WR51_RS20115	COG4703	Protein of unknown function (DUF1797)
WR51_RS20130	COG2200	EAL domain
WR51_RS20135	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS20140	COG1408	metallophosphoesterase
WR51_RS20185	COG2814	Major facilitator Superfamily
WR51_RS20205	COG3209	COG3209 Rhs family protein
WR51_RS20215	COG2205	protein histidine kinase activity
WR51_RS20225	COG0436	Aminotransferase
WR51_RS20230	COG1609	Transcriptional regulator
WR51_RS20235	COG3833	ABC-type maltose transport systems, permease component
WR51_RS20240	COG1175	transmembrane transport
WR51_RS20245	COG2182	Extracellular solute-binding protein
WR51_RS20255	COG0366	Alpha amylase catalytic
WR51_RS20260	COG3842	ATPase activity
WR51_RS20300	COG0183	Belongs to the thiolase family
WR51_RS20330	COG1695	Transcriptional regulator
WR51_RS20335	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS20355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WR51_RS20360	COG0436	Aminotransferase
WR51_RS20395	COG2084	Dehydrogenase
WR51_RS20405	COG2199	diguanylate cyclase activity
WR51_RS20410	COG0778	Nitroreductase
WR51_RS20435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WR51_RS20435	COG2190	(PTS) system
WR51_RS20435	COG1263	PTS System
WR51_RS20440	COG3711	transcriptional antiterminator
WR51_RS20450	COG2188	Transcriptional regulator
WR51_RS20460	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WR51_RS20485	COG1547	Domain of unknown function (DUF309)
WR51_RS20490	COG0456	acetyltransferase
WR51_RS20495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WR51_RS20500	COG4086	secreted protein
WR51_RS20505	COG0561	phosphatase activity
WR51_RS20510	COG0697	spore germination
WR51_RS20525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR51_RS20550	COG0733	neurotransmitter:sodium symporter activity
WR51_RS20570	COG1686	Belongs to the peptidase S11 family
WR51_RS20575	COG1725	Transcriptional regulator
WR51_RS20580	COG1131	(ABC) transporter
WR51_RS20595	COG1846	Transcriptional regulator
WR51_RS20610	COG0598	Magnesium transport protein CorA
WR51_RS20635	COG4974	Belongs to the 'phage' integrase family
WR51_RS20645	COG0735	belongs to the Fur family
WR51_RS20650	COG1300	Membrane
WR51_RS20670	COG0667	Aldo Keto reductase
WR51_RS20675	COG0656	L-ascorbic acid biosynthetic process
WR51_RS20680	COG0456	acetyltransferase
WR51_RS20680	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
WR51_RS20690	COG4085	toxin activity
WR51_RS20690	COG0737	Belongs to the 5'-nucleotidase family
WR51_RS20690	COG1525	nuclease
WR51_RS20700	COG0596	Alpha beta hydrolase
WR51_RS20705	COG2056	Na+-H+ antiporter family
WR51_RS20710	COG1609	Transcriptional regulator
WR51_RS20715	COG0456	acetyltransferase
WR51_RS20720	COG1073	alpha beta
WR51_RS20735	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WR51_RS20735	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WR51_RS20740	COG0307	riboflavin synthase, alpha
WR51_RS20770	COG1073	alpha beta
WR51_RS20770	COG2226	methyltransferase
WR51_RS20785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WR51_RS20795	COG1757	Na H antiporter
WR51_RS20800	COG0737	Belongs to the 5'-nucleotidase family
WR51_RS20810	COG1522	sequence-specific DNA binding
WR51_RS20850	COG5444	nuclease activity
WR51_RS20885	COG0300	oxidoreductase activity
WR51_RS20890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS20895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_RS20900	COG1760	l-serine dehydratase
WR51_RS20905	COG1760	l-serine dehydratase
WR51_RS20930	COG1285	pathogenesis
WR51_RS20940	COG2195	Cleaves the N-terminal amino acid of tripeptides
WR51_RS20945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS20955	COG1376	ErfK ybiS ycfS ynhG family protein
WR51_RS20960	COG4129	membrane
WR51_RS20965	COG1126	abc transporter atp-binding protein
WR51_RS20970	COG0765	amino acid transport
WR51_RS20975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WR51_RS20995	COG2323	membrane
WR51_RS21000	COG0772	Belongs to the SEDS family
WR51_RS21005	COG0508	dehydrogenase complex catalyzes the overall conversion of
WR51_RS21010	COG0022	dehydrogenase e1 component
WR51_RS21015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WR51_RS21020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WR51_RS21035	COG0280	phosphate acetyltransferase
WR51_RS21040	COG3829	transcription factor binding
WR51_RS21040	COG3290	protein histidine kinase activity
WR51_RS21050	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_RS21055	COG3093	addiction module antidote protein HigA
WR51_RS21070	COG0750	zinc metalloprotease
WR51_RS21075	COG0497	DNA recombination
WR51_RS21085	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
WR51_RS21095	COG0142	geranyltranstransferase activity
WR51_RS21120	COG1302	Protein conserved in bacteria
WR51_RS21125	COG0439	Biotin carboxylase
WR51_RS21130	COG0511	ligase activity, forming carbon-carbon bonds
WR51_RS21170	COG3854	ATPases associated with a variety of cellular activities
WR51_RS21195	COG0006	proline dipeptidase activity
WR51_RS21210	COG3872	metal-dependent enzyme
WR51_RS21220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WR51_RS21255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_RS21265	COG1609	Transcriptional regulator
WR51_RS21275	COG2076	Multidrug Resistance protein
WR51_RS21280	COG2076	Multidrug Resistance protein
WR51_RS21315	COG1725	Transcriptional regulator
WR51_RS21345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR51_RS21410	COG1459	type II secretion system
WR51_RS21415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WR51_RS21480	COG0646	methionine synthase
WR51_RS21480	COG1410	methionine synthase
WR51_RS21485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
WR51_RS21485	COG0646	methionine synthase
WR51_RS21490	COG0626	cystathionine gamma-synthase activity
WR51_RS21495	COG0626	cystathionine gamma-synthase activity
WR51_RS21515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS21520	COG1940	carbohydrate kinase activity
WR51_RS21525	COG4483	Protein conserved in bacteria
WR51_RS21530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WR51_RS21535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WR51_RS21540	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WR51_RS21545	COG0704	Plays a role in the regulation of phosphate uptake
WR51_RS21555	COG0573	inorganic phosphate transmembrane transporter activity
WR51_RS21560	COG0573	inorganic phosphate transmembrane transporter activity
WR51_RS21565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
WR51_RS21570	COG0768	penicillin binding
WR51_RS21575	COG0477	Major facilitator Superfamily
WR51_RS21580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WR51_RS21590	COG5521	maltodextrose utilization protein MalA
WR51_RS21605	COG0735	belongs to the Fur family
WR51_RS21610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WR51_RS21615	COG1121	(ABC) transporter
WR51_RS21620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS21650	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WR51_RS21655	COG2384	SAM-dependent methyltransferase
WR51_RS21665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WR51_RS21670	COG0358	DNA primase activity
WR51_RS21680	COG0517	IMP dehydrogenase activity
WR51_RS21695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WR51_RS21700	COG0295	cytidine deaminase activity
WR51_RS21705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WR51_RS21715	COG1480	7TM receptor with intracellular HD hydrolase
WR51_RS21720	COG1702	phosphate starvation-inducible protein PhoH
WR51_RS21740	COG1610	YqeY-like protein
WR51_RS21745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WR51_RS21750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WR51_RS21755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WR51_RS21785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WR51_RS21790	COG1733	regulation of RNA biosynthetic process
WR51_RS21815	COG1466	dna polymerase III delta subunit
WR51_RS21825	COG0658	competence protein
WR51_RS21825	COG2333	competence protein COMEC
WR51_RS21830	COG2131	deaminase
WR51_RS21835	COG1596	polysaccharide export
WR51_RS21835	COG1555	photosystem II stabilization
WR51_RS21840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WR51_RS21845	COG2226	methyltransferase
WR51_RS21850	COG0799	negative regulation of ribosome biogenesis
WR51_RS21855	COG1713	HD superfamily hydrolase involved in NAD metabolism
WR51_RS21865	COG1534	Rna-binding protein
WR51_RS21875	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WR51_RS21880	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
WR51_RS21905	COG1595	DNA-templated transcription, initiation
WR51_RS21915	COG0778	Nitroreductase
WR51_RS21920	COG2357	RelA SpoT domain protein
WR51_RS21930	COG1785	Belongs to the alkaline phosphatase family
WR51_RS21940	COG2267	carboxylic ester hydrolase activity
WR51_RS21980	COG3186	Phenylalanine-4-hydroxylase
WR51_RS21990	COG2514	catechol 2,3-dioxygenase activity
WR51_RS21995	COG2259	Doxx family
WR51_RS22035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS22045	COG1454	alcohol dehydrogenase
WR51_RS22045	COG1012	belongs to the aldehyde dehydrogenase family
WR51_RS22050	COG0626	cystathionine gamma-synthase activity
WR51_RS22055	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WR51_RS22080	COG0768	penicillin binding
WR51_RS22095	COG0826	peptidase U32
WR51_RS22100	COG0826	peptidase U32
WR51_RS22105	COG4122	O-methyltransferase activity
WR51_RS22110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WR51_RS22125	COG4472	Bacterial protein of unknown function (DUF965)
WR51_RS22140	COG0628	permease
WR51_RS22160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WR51_RS22175	COG1104	cysteine desulfurase activity
WR51_RS22180	COG1959	2 iron, 2 sulfur cluster binding
WR51_RS22185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WR51_RS22195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WR51_RS22220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WR51_RS22230	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WR51_RS22230	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
WR51_RS22235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WR51_RS22240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WR51_RS22240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WR51_RS22250	COG2244	polysaccharide biosynthetic process
WR51_RS22255	COG2323	membrane
WR51_RS22265	COG1862	Preprotein translocase
WR51_RS22295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
WR51_RS22325	COG0157	Belongs to the NadC ModD family
WR51_RS22330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WR51_RS22335	COG1104	cysteine desulfurase activity
WR51_RS22340	COG1827	regulation of RNA biosynthetic process
WR51_RS22345	COG2258	MOSC domain
WR51_RS22350	COG0077	Prephenate dehydratase
WR51_RS22355	COG0577	efflux transmembrane transporter activity
WR51_RS22360	COG0577	efflux transmembrane transporter activity
WR51_RS22365	COG1136	(ABC) transporter
WR51_RS22370	COG5002	protein histidine kinase activity
WR51_RS22375	COG0745	RESPONSE REGULATOR receiver
WR51_RS22385	COG3290	protein histidine kinase activity
WR51_RS22395	COG2868	ribosomal protein
WR51_RS22405	COG1530	ribonuclease E activity
WR51_RS22410	COG1994	Peptidase M50
WR51_RS22415	COG0739	heme binding
WR51_RS22420	COG2894	cell division
WR51_RS22440	COG1077	Cell shape determining protein MreB Mrl
WR51_RS22460	COG0285	dihydrofolate synthase activity
WR51_RS22475	COG1388	LysM domain
WR51_RS22485	COG0113	porphobilinogen synthase activity
WR51_RS22490	COG1587	Uroporphyrinogen-III synthase
WR51_RS22500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WR51_RS22510	COG1846	Transcriptional regulator
WR51_RS22515	COG1764	response to oxidative stress
WR51_RS22530	COG0470	DNA polymerase III
WR51_RS22530	COG1067	ATP-dependent peptidase activity
WR51_RS22570	COG0622	Phosphoesterase
WR51_RS22585	COG5401	PFAM Sporulation and spore germination
WR51_RS22605	COG1309	transcriptional regulator
WR51_RS22615	COG2197	response regulator
WR51_RS22620	COG2233	PERMEase
WR51_RS22625	COG0402	S-adenosylhomocysteine deaminase activity
WR51_RS22630	COG1983	PspC domain protein
WR51_RS22635	COG1396	sequence-specific DNA binding
WR51_RS22640	COG0697	spore germination
WR51_RS22650	COG1959	2 iron, 2 sulfur cluster binding
WR51_RS22655	COG1668	transmembrane transport
WR51_RS22660	COG4152	abc transporter atp-binding protein
WR51_RS22665	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
WR51_RS22670	COG1360	Flagellar Motor Protein
WR51_RS22675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WR51_RS22680	COG1876	peptidase activity
WR51_RS22685	COG0824	Thioesterase
WR51_RS22690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WR51_RS22695	COG1053	succinate dehydrogenase
WR51_RS22700	COG2009	succinate dehydrogenase
WR51_RS22705	COG1719	4-vinyl reductase, 4VR
WR51_RS22715	COG3118	belongs to the thioredoxin family
WR51_RS22720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
WR51_RS22725	COG2086	electron transfer activity
WR51_RS22730	COG1024	Enoyl-CoA hydratase
WR51_RS22735	COG1309	transcriptional regulator
WR51_RS22740	COG0318	PFAM AMP-dependent synthetase and ligase
WR51_RS22765	COG2318	DinB family
WR51_RS22790	COG1131	(ABC) transporter
WR51_RS22795	COG2205	protein histidine kinase activity
WR51_RS22800	COG0745	RESPONSE REGULATOR receiver
WR51_RS22810	COG4895	conserved protein (DUF2196)
WR51_RS22815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WR51_RS22825	COG4509	Sortase family
WR51_RS22830	COG1120	ATPase activity
WR51_RS22845	COG5386	Cell surface protein
WR51_RS22855	COG5386	Cell surface protein
WR51_RS22860	COG1114	Component of the transport system for branched-chain amino acids
WR51_RS22865	COG1187	pseudouridine synthase activity
WR51_RS22875	COG1796	DNA polymerase
WR51_RS22875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WR51_RS22880	COG1286	toxin biosynthetic process
WR51_RS22915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WR51_RS22920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WR51_RS22930	COG1418	mRNA catabolic process
WR51_RS22950	COG2814	Major facilitator Superfamily
WR51_RS22955	COG1566	PFAM secretion protein HlyD family protein
WR51_RS22960	COG1309	transcriptional regulator
WR51_RS22965	COG1363	Peptidase, m42
WR51_RS22990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WR51_RS23005	COG1484	DNA-dependent DNA replication
WR51_RS23010	COG3611	Membrane attachment protein
WR51_RS23020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
WR51_RS23025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WR51_RS23030	COG0237	dephospho-CoA kinase activity
WR51_RS23035	COG1971	Probably functions as a manganese efflux pump
WR51_RS23045	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR51_RS23045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WR51_RS23050	COG5002	protein histidine kinase activity
WR51_RS23055	COG0745	RESPONSE REGULATOR receiver
WR51_RS23075	COG0538	isocitrate dehydrogenase activity
WR51_RS23080	COG0372	Belongs to the citrate synthase family
WR51_RS23090	COG0628	permease
WR51_RS23095	COG3030	protein affecting phage T7 exclusion by the F plasmid
WR51_RS23120	COG1725	Transcriptional regulator
WR51_RS23125	COG0281	malic enzyme
WR51_RS23130	COG0587	DNA-directed DNA polymerase activity
WR51_RS23145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WR51_RS23160	COG4109	DRTGG domain
WR51_RS23175	COG0006	proline dipeptidase activity
WR51_RS23210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS23215	COG0662	Cupin 2, conserved barrel domain protein
WR51_RS23230	COG1028	Short-chain dehydrogenase reductase Sdr
WR51_RS23235	COG0589	response to stress
WR51_RS23275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS23300	COG0827	DNA restriction-modification system
WR51_RS23305	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
WR51_RS23310	COG3874	Sporulation protein YtfJ
WR51_RS23325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
WR51_RS23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR51_RS23350	COG1104	cysteine desulfurase activity
WR51_RS23370	COG1136	(ABC) transporter
WR51_RS23395	COG0583	DNA-binding transcription factor activity
WR51_RS23400	COG0697	spore germination
WR51_RS23405	COG1309	transcriptional regulator
WR51_RS23410	COG1956	GAF domain-containing protein
WR51_RS23415	COG0626	cystathionine gamma-synthase activity
WR51_RS23445	COG1595	DNA-templated transcription, initiation
WR51_RS23455	COG0110	maltose O-acetyltransferase activity
WR51_RS23460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WR51_RS23465	COG0454	-acetyltransferase
WR51_RS23470	COG0517	IMP dehydrogenase activity
WR51_RS23475	COG0123	including yeast histone deacetylase and acetoin utilization protein
WR51_RS23480	COG2267	carboxylic ester hydrolase activity
WR51_RS23490	COG0745	RESPONSE REGULATOR receiver
WR51_RS23495	COG5002	protein histidine kinase activity
WR51_RS23500	COG0666	response to abiotic stimulus
WR51_RS23530	COG1609	Transcriptional regulator
WR51_RS23535	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR51_RS23535	COG1605	Chorismate mutase
WR51_RS23540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WR51_RS23540	COG1605	Chorismate mutase
WR51_RS23545	COG4851	CamS sex pheromone cAM373 precursor
WR51_RS23550	COG3118	belongs to the thioredoxin family
WR51_RS23560	COG2309	aminopeptidase activity
WR51_RS23575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS23580	COG0697	spore germination
WR51_RS23585	COG0789	Transcriptional regulator
WR51_RS23600	COG1674	ftsk spoiiie
WR51_RS23605	COG0860	N-Acetylmuramoyl-L-alanine amidase
WR51_RS23615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WR51_RS23625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_RS23630	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
WR51_RS23635	COG1363	Peptidase, m42
WR51_RS23645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS23660	COG0510	thiamine kinase activity
WR51_RS23665	COG1523	belongs to the glycosyl hydrolase 13 family
WR51_RS23675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WR51_RS23680	COG1349	DNA-binding transcription factor activity
WR51_RS23685	COG1187	pseudouridine synthase activity
WR51_RS23690	COG2244	polysaccharide biosynthetic process
WR51_RS23695	COG2081	HI0933 family
WR51_RS23700	COG2814	Major facilitator Superfamily
WR51_RS23710	COG3832	glyoxalase III activity
WR51_RS23730	COG1329	Transcriptional regulator
WR51_RS23755	COG0314	molybdopterin synthase activity
WR51_RS23760	COG1763	Mo-molybdopterin cofactor biosynthetic process
WR51_RS23765	COG0303	'Molybdopterin
WR51_RS23775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WR51_RS23780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WR51_RS23800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WR51_RS23810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WR51_RS23850	COG2814	Major facilitator Superfamily
WR51_RS23855	COG0475	glutathione-regulated potassium exporter activity
WR51_RS23860	COG0490	domain, Protein
WR51_RS23865	COG0582	viral genome integration into host DNA
WR51_RS23875	COG1136	(ABC) transporter
WR51_RS23895	COG1242	4 iron, 4 sulfur cluster binding
WR51_RS23900	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
WR51_RS23915	COG1794	racemase activity, acting on amino acids and derivatives
WR51_RS23935	COG2267	carboxylic ester hydrolase activity
WR51_RS23940	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WR51_RS23945	COG0671	phosphoesterase, PA-phosphatase related
WR51_RS23950	COG0438	transferase activity, transferring glycosyl groups
WR51_RS24030	COG5002	protein histidine kinase activity
WR51_RS24035	COG3852	Histidine kinase
WR51_RS24040	COG0753	catalase activity
WR51_RS24045	COG2267	carboxylic ester hydrolase activity
WR51_RS24050	COG1368	sulfuric ester hydrolase activity
WR51_RS24070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WR51_RS24075	COG1116	anion transmembrane transporter activity
WR51_RS24080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WR51_RS24095	COG0546	phosphoglycolate phosphatase activity
WR51_RS24105	COG0494	nUDIX hydrolase
WR51_RS24135	COG1854	S-ribosylhomocysteine lyase activity
WR51_RS24145	COG0288	reversible hydration of carbon dioxide
WR51_RS24150	COG1271	oxidase subunit
WR51_RS24155	COG1294	oxidase, subunit
WR51_RS24170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS24190	COG1842	Phage shock protein A
WR51_RS24215	COG3859	Proton-coupled thiamine transporter YuaJ
WR51_RS24220	COG5002	protein histidine kinase activity
WR51_RS24225	COG0745	RESPONSE REGULATOR receiver
WR51_RS24250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
WR51_RS24255	COG1597	lipid kinase activity
WR51_RS24280	COG0586	Pfam SNARE associated Golgi protein
WR51_RS24290	COG0577	efflux transmembrane transporter activity
WR51_RS24295	COG1136	(ABC) transporter
WR51_RS24300	COG3708	Transcriptional regulator
WR51_RS24300	COG2207	Transcriptional regulator
WR51_RS24310	COG5658	integral membrane protein
WR51_RS24315	COG0640	Transcriptional regulator
WR51_RS24320	COG0745	RESPONSE REGULATOR receiver
WR51_RS24325	COG2205	protein histidine kinase activity
WR51_RS24330	COG0577	efflux transmembrane transporter activity
WR51_RS24335	COG0577	efflux transmembrane transporter activity
WR51_RS24340	COG1136	(ABC) transporter
WR51_RS24345	COG0577	efflux transmembrane transporter activity
WR51_RS24370	COG2188	Transcriptional regulator
WR51_RS24390	COG3964	amidohydrolase
WR51_RS24410	COG4948	Mandelate Racemase Muconate Lactonizing
WR51_RS24420	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WR51_RS24425	COG0596	Alpha beta hydrolase
WR51_RS24435	COG1169	isochorismate synthase
WR51_RS24440	COG1575	Belongs to the MenA family. Type 1 subfamily
WR51_RS24445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WR51_RS24450	COG1278	Cold shock
WR51_RS24475	COG0058	SHG alpha-glucan phosphorylase activity
WR51_RS24485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WR51_RS24505	COG1404	Belongs to the peptidase S8 family
WR51_RS24640	COG1285	pathogenesis
WR51_RS24645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WR51_RS24660	COG2155	Conserved Protein
WR51_RS24665	COG1098	S1 RNA binding domain
WR51_RS24670	COG0436	Aminotransferase
WR51_RS24675	COG1522	sequence-specific DNA binding
WR51_RS24680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WR51_RS24685	COG2267	carboxylic ester hydrolase activity
WR51_RS24695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WR51_RS24715	COG5018	Exonuclease
WR51_RS24720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR51_RS24740	COG2050	protein possibly involved in aromatic compounds catabolism
WR51_RS24750	COG1268	BioY protein
WR51_RS24760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR51_RS24765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WR51_RS24785	COG2076	Multidrug Resistance protein
WR51_RS24790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WR51_RS24800	COG3584	3D domain protein
WR51_RS24815	COG1252	NADH dehydrogenase
WR51_RS24825	COG3708	Transcriptional regulator
WR51_RS24840	COG1683	Conserved Protein
WR51_RS24850	COG4122	O-methyltransferase activity
WR51_RS24865	COG0316	Belongs to the HesB IscA family
WR51_RS24880	COG1252	NADH dehydrogenase
WR51_RS24895	COG0390	transport system, permease component
WR51_RS24900	COG2824	Alkylphosphonate utilization operon protein PhnA
WR51_RS24925	COG4837	Protein of unknown function (DUF1462)
WR51_RS24930	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WR51_RS24940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WR51_RS24945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WR51_RS24965	COG1358	cellular component organization or biogenesis
WR51_RS24975	COG2249	NAD(P)H dehydrogenase (quinone) activity
WR51_RS24980	COG0647	UMP catabolic process
WR51_RS24990	COG2445	Protein of unknown function DUF86
WR51_RS24995	COG1494	fructose-1,6-bisphosphatase
WR51_RS25015	COG4470	Protein conserved in bacteria
WR51_RS25025	COG0789	Transcriptional regulator
WR51_RS25030	COG4377	Putative membrane peptidase family (DUF2324)
WR51_RS25055	COG0739	heme binding
WR51_RS25065	COG3377	Domain of unknown function (DUF1805)
WR51_RS25070	COG0737	Belongs to the 5'-nucleotidase family
WR51_RS25075	COG0719	Fe-S assembly protein
WR51_RS25080	COG0822	iron-sulfur transferase activity
WR51_RS25085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WR51_RS25090	COG0719	Fe-S assembly protein
WR51_RS25095	COG0396	ATPase activity
WR51_RS25100	COG1464	Belongs to the NlpA lipoprotein family
WR51_RS25105	COG1464	Belongs to the NlpA lipoprotein family
WR51_RS25110	COG2011	ABC-type metal ion transport system permease component
WR51_RS25125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WR51_RS25130	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
WR51_RS25140	COG1393	Belongs to the ArsC family
WR51_RS25175	COG0039	L-malate dehydrogenase activity
WR51_RS25195	COG1309	transcriptional regulator
WR51_RS25200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WR51_RS25205	COG1960	acyl-CoA dehydrogenase activity
WR51_RS25210	COG0183	Belongs to the thiolase family
WR51_RS25215	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR51_RS25215	COG1024	Enoyl-CoA hydratase
WR51_RS25225	COG1686	Belongs to the peptidase S11 family
WR51_RS25240	COG0011	TIGRFAM Protein of
WR51_RS25245	COG0840	transmembrane signaling receptor activity
WR51_RS25260	COG2814	Major facilitator Superfamily
WR51_RS25265	COG0531	amino acid
WR51_RS25290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
WR51_RS25320	COG0586	Pfam SNARE associated Golgi protein
WR51_RS25330	COG1376	ErfK ybiS ycfS ynhG family protein
WR51_RS25335	COG0745	RESPONSE REGULATOR receiver
WR51_RS25340	COG5002	protein histidine kinase activity
WR51_RS25370	COG0840	transmembrane signaling receptor activity
WR51_RS25375	COG2151	metal-sulfur cluster biosynthetic enzyme
WR51_RS25380	COG3227	Zinc metalloprotease (Elastase)
WR51_RS25400	COG0586	Pfam SNARE associated Golgi protein
WR51_RS25405	COG0475	glutathione-regulated potassium exporter activity
WR51_RS25410	COG0490	domain, Protein
WR51_RS25415	COG1115	amino acid carrier protein
WR51_RS25420	COG0783	Belongs to the Dps family
WR51_RS25430	COG2318	DinB family
WR51_RS25440	COG1611	Belongs to the LOG family
WR51_RS25450	COG1528	Iron-storage protein
WR51_RS25460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS25465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS25470	COG1115	amino acid carrier protein
WR51_RS25475	COG1115	amino acid carrier protein
WR51_RS25480	COG2910	NAD(P)H-binding
WR51_RS25495	COG0656	L-ascorbic acid biosynthetic process
WR51_RS25500	COG2814	Major facilitator Superfamily
WR51_RS25505	COG1733	regulation of RNA biosynthetic process
WR51_RS25515	COG1252	NADH dehydrogenase
WR51_RS25520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WR51_RS25565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WR51_RS25580	COG1335	isochorismatase
WR51_RS25585	COG1522	sequence-specific DNA binding
WR51_RS25595	COG1522	sequence-specific DNA binding
WR51_RS25600	COG0288	reversible hydration of carbon dioxide
WR51_RS25605	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
WR51_RS25610	COG2233	PERMEase
WR51_RS25660	COG0557	exoribonuclease II activity
WR51_RS25665	COG1647	Serine aminopeptidase, S33
WR51_RS25670	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WR51_RS25675	COG1346	cytolysis
WR51_RS25710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WR51_RS25725	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WR51_RS25735	COG1668	transmembrane transport
WR51_RS25740	COG4152	abc transporter atp-binding protein
WR51_RS25745	COG4585	Histidine kinase
WR51_RS25810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WR51_RS25825	COG2323	membrane
WR51_RS25835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WR51_RS25845	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WR51_RS25855	COG1051	belongs to the nudix hydrolase family
WR51_RS25865	COG0492	ferredoxin-NADP+ reductase activity
WR51_RS25870	COG0457	Tetratricopeptide repeat
WR51_RS25875	COG0110	maltose O-acetyltransferase activity
WR51_RS25895	COG1950	PFAM Membrane protein of
WR51_RS25900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WR51_RS25920	COG0789	Transcriptional regulator
WR51_RS25940	COG0583	DNA-binding transcription factor activity
WR51_RS25950	COG0655	NAD(P)H dehydrogenase (quinone) activity
WR51_RS25955	COG0488	(ABC) transporter
WR51_RS25965	COG1132	(ABC) transporter
WR51_RS25970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_RS25975	COG0793	Belongs to the peptidase S41A family
WR51_RS25975	COG3409	Peptidoglycan-binding domain 1 protein
WR51_RS25980	COG2177	Part of the ABC transporter FtsEX involved in
WR51_RS25985	COG2884	Cell division ATP-binding protein ftsE
WR51_RS25995	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WR51_RS26010	COG1131	(ABC) transporter
WR51_RS26040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WR51_RS26045	COG1278	Cold shock
WR51_RS26050	COG1040	competence protein
WR51_RS26055	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
WR51_RS26060	COG1388	LysM domain
WR51_RS26060	COG0791	NLP P60 protein
WR51_RS26065	COG1733	regulation of RNA biosynthetic process
WR51_RS26070	COG1307	EDD domain protein, DegV family
WR51_RS26075	COG1739	Uncharacterized protein family UPF0029
WR51_RS26080	COG1316	TRANSCRIPTIONal
WR51_RS26085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WR51_RS26090	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR51_RS26095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WR51_RS26105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WR51_RS26105	COG3933	PFAM sigma-54 factor interaction domain-containing protein
WR51_RS26125	COG1486	melibiose metabolic process
WR51_RS26130	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR51_RS26135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR51_RS26145	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WR51_RS26155	COG1447	Phosphotransferase system cellobiose-specific component IIA
WR51_RS26165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WR51_RS26170	COG1301	dicarboxylic acid transport
WR51_RS26185	COG1511	domain protein
WR51_RS26190	COG0583	DNA-binding transcription factor activity
WR51_RS26195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
WR51_RS26205	COG1271	oxidase subunit
WR51_RS26210	COG1294	oxidase, subunit
WR51_RS26215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
WR51_RS26225	COG1620	l-lactate permease
WR51_RS26235	COG2389	metal-binding protein
WR51_RS26245	COG1368	sulfuric ester hydrolase activity
WR51_RS26255	COG0791	NLP P60 protein
WR51_RS26255	COG1388	LysM domain
WR51_RS26260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WR51_RS26270	COG1215	transferase activity, transferring glycosyl groups
WR51_RS26280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR51_RS26285	COG3584	3D domain protein
WR51_RS26285	COG1388	LysM domain
WR51_RS26310	COG4715	Zinc finger, swim domain protein
WR51_RS26315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WR51_RS26355	COG0577	efflux transmembrane transporter activity
WR51_RS26360	COG1136	(ABC) transporter
WR51_RS26385	COG5002	protein histidine kinase activity
WR51_RS26390	COG0745	RESPONSE REGULATOR receiver
WR51_RS26395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR51_RS26400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR51_RS26410	COG1316	TRANSCRIPTIONal
WR51_RS26420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
WR51_RS26435	COG0438	transferase activity, transferring glycosyl groups
WR51_RS26440	COG1215	transferase activity, transferring glycosyl groups
WR51_RS26445	COG0438	transferase activity, transferring glycosyl groups
WR51_RS26460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WR51_RS26465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WR51_RS26470	COG1086	Polysaccharide biosynthesis protein
WR51_RS26475	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WR51_RS26480	COG4464	protein tyrosine phosphatase activity
WR51_RS26485	COG0489	protein tyrosine kinase activity
WR51_RS26490	COG3944	biosynthesis protein
WR51_RS26495	COG0489	protein tyrosine kinase activity
WR51_RS26510	COG1609	Transcriptional regulator
WR51_RS26520	COG0739	heme binding
WR51_RS26535	COG3279	Response regulator of the LytR AlgR family
WR51_RS26540	COG2385	sporulation resulting in formation of a cellular spore
WR51_RS26555	COG4836	Membrane
WR51_RS26560	COG1007	ATP synthesis coupled electron transport
WR51_RS26565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WR51_RS26570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
WR51_RS26580	COG0839	Belongs to the complex I subunit 6 family
WR51_RS26600	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WR51_RS26615	COG5001	Diguanylate cyclase
WR51_RS26615	COG3300	MHYT domain
WR51_RS26665	COG0356	it plays a direct role in the translocation of protons across the membrane
WR51_RS26700	COG0698	ribose 5-phosphate isomerase
WR51_RS26710	COG2190	(PTS) system
WR51_RS26715	COG2259	Doxx family
WR51_RS26720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
WR51_RS26740	COG0009	L-threonylcarbamoyladenylate synthase
WR51_RS26775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
WR51_RS26780	COG1494	fructose-1,6-bisphosphatase
WR51_RS26800	COG4821	SIS domain
WR51_RS26810	COG3343	RNA polymerase activity
WR51_RS26820	COG1960	acyl-CoA dehydrogenase activity
WR51_RS26825	COG1960	acyl-CoA dehydrogenase activity
WR51_RS26830	COG1250	3-hydroxyacyl-CoA dehydrogenase
WR51_RS26835	COG0183	Belongs to the thiolase family
WR51_RS26840	COG2181	nitrate reductase activity
WR51_RS26840	COG0247	lactate metabolic process
WR51_RS26845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WR51_RS26855	COG5001	Diguanylate cyclase
WR51_RS26855	COG3300	MHYT domain
WR51_RS26870	COG3227	Zinc metalloprotease (Elastase)
WR51_RS26875	COG2197	response regulator
WR51_RS26880	COG4585	Histidine kinase
WR51_RS26885	COG0842	Transport permease protein
WR51_RS26890	COG1131	(ABC) transporter
WR51_RS26895	COG0024	Methionine aminopeptidase
WR51_RS26905	COG2234	aminopeptidase activity
WR51_RS26925	COG1595	DNA-templated transcription, initiation
WR51_RS26935	COG4506	Protein conserved in bacteria
WR51_RS26940	COG1619	proteins homologs of microcin C7 resistance protein MccF
WR51_RS26965	COG2814	Major facilitator Superfamily
WR51_RS26970	COG0789	Transcriptional regulator
WR51_RS26975	COG0584	glycerophosphoryl diester phosphodiesterase
WR51_RS26980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WR51_RS26990	COG1994	Peptidase M50
WR51_RS27000	COG1078	dGTPase activity
WR51_RS27005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WR51_RS27010	COG1120	ATPase activity
WR51_RS27015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS27020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS27040	COG0280	phosphate acetyltransferase
WR51_RS27055	COG3773	Cell wall hydrolase
WR51_RS27065	COG2363	Small membrane protein
WR51_RS27075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WR51_RS27080	COG2233	PERMEase
WR51_RS27085	COG0561	phosphatase activity
WR51_RS27090	COG2814	Major facilitator Superfamily
WR51_RS27100	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
WR51_RS27105	COG1131	(ABC) transporter
WR51_RS27110	COG2755	lipolytic protein G-D-S-L family
WR51_RS27115	COG1609	Transcriptional regulator
WR51_RS27125	COG0460	homoserine dehydrogenase
WR51_RS27135	COG2873	o-acetylhomoserine
WR51_RS27145	COG1011	Hydrolase
WR51_RS27150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WR51_RS27160	COG2197	response regulator
WR51_RS27165	COG4585	Histidine kinase
WR51_RS27165	COG2203	Gaf domain
WR51_RS27170	COG0351	phosphomethylpyrimidine kinase
WR51_RS27175	COG3706	GGDEF domain
WR51_RS27180	COG2879	small protein
WR51_RS27185	COG1966	Carbon starvation protein
WR51_RS27190	COG3279	Response regulator of the LytR AlgR family
WR51_RS27195	COG0477	Major facilitator Superfamily
WR51_RS27205	COG0438	transferase activity, transferring glycosyl groups
WR51_RS27220	COG0840	transmembrane signaling receptor activity
WR51_RS27230	COG1607	acyl-coa hydrolase
WR51_RS27235	COG1216	Glycosyl transferase, family 2
WR51_RS27245	COG1216	Glycosyl transferase, family 2
WR51_RS27255	COG4485	Bacterial membrane protein, YfhO
WR51_RS27260	COG0463	Glycosyl transferase, family 2
WR51_RS27270	COG1309	transcriptional regulator
WR51_RS27275	COG0488	(ABC) transporter
WR51_RS27280	COG1309	transcriptional regulator
WR51_RS27285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WR51_RS27290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR51_RS27290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WR51_RS27295	COG0628	permease
WR51_RS27315	COG3275	phosphorelay sensor kinase activity
WR51_RS27320	COG2814	Major facilitator Superfamily
WR51_RS27325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
WR51_RS27330	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
WR51_RS27355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WR51_RS27360	COG1272	protein, Hemolysin III
WR51_RS27380	COG1164	Oligoendopeptidase f
WR51_RS27390	COG5002	protein histidine kinase activity
WR51_RS27405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WR51_RS27410	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
WR51_RS27415	COG4853	Protein conserved in bacteria
WR51_RS27425	COG5002	protein histidine kinase activity
WR51_RS27430	COG0745	RESPONSE REGULATOR receiver
WR51_RS27460	COG0305	Participates in initiation and elongation during chromosome replication
WR51_RS27470	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
WR51_RS27475	COG4241	membrane
WR51_RS27485	COG0629	single-stranded DNA binding
WR51_RS27495	COG0012	GTP binding
WR51_RS27500	COG4481	Protein conserved in bacteria
WR51_RS27505	COG0668	transmembrane transport
WR51_RS27515	COG1475	DNA binding
WR51_RS27520	COG1192	Involved in chromosome partitioning
WR51_RS27545	COG1847	R3H domain protein
WR51_RS27560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WR51_RS27595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
WR51_RS27670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WR51_RS27760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WR51_RS28270	COG4149	molybdate abc transporter
WR51_RS28275	COG0725	ABC transporter, periplasmic molybdate-binding protein
WR51_RS28430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WR51_RS29020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WR51_RS29165	COG0366	Alpha amylase catalytic
WR51_RS29280	COG0488	(ABC) transporter