locus-tag	class	description
BF28_RS00005	COG4856	YbbR-like protein
BF28_RS00130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF28_RS00360	COG2194	sulfuric ester hydrolase activity
BF28_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF28_RS00635	COG0542	response to heat
BF28_RS00760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_RS01125	COG0706	membrane insertase activity
BF28_RS01180	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF28_RS01190	COG0305	Participates in initiation and elongation during chromosome replication
BF28_RS01370	COG0628	permease
BF28_RS01470	COG0477	Major facilitator Superfamily
BF28_RS01490	COG2199	diguanylate cyclase activity
BF28_RS01820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS01830	COG0183	Belongs to the thiolase family
BF28_RS01915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF28_RS01935	COG2890	protein-(glutamine-N5) methyltransferase activity
BF28_RS02170	COG0110	maltose O-acetyltransferase activity
BF28_RS02335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_RS02405	COG1368	sulfuric ester hydrolase activity
BF28_RS02500	COG1511	domain protein
BF28_RS02530	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF28_RS02610	COG0726	polysaccharide deacetylase
BF28_RS02615	COG2194	sulfuric ester hydrolase activity
BF28_RS02625	COG0489	protein tyrosine kinase activity
BF28_RS02630	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_RS02655	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF28_RS02690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BF28_RS02700	COG0024	Methionine aminopeptidase
BF28_RS02710	COG0201	protein transport
BF28_RS02770	COG0255	Belongs to the universal ribosomal protein uL29 family
BF28_RS02840	COG1358	cellular component organization or biogenesis
BF28_RS02855	COG2813	Specifically methylates the guanine in position
BF28_RS02875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BF28_RS02880	COG0250	Participates in transcription elongation, termination and antitermination
BF28_RS02885	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF28_RS02900	COG3688	RNA-binding protein containing a PIN domain
BF28_RS02905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF28_RS02920	COG1045	serine acetyltransferase
BF28_RS02940	COG4956	integral membrane protein (PIN domain superfamily)
BF28_RS02950	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF28_RS02955	COG0542	response to heat
BF28_RS02965	COG3880	PFAM UvrB UvrC protein
BF28_RS03055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF28_RS03060	COG1396	sequence-specific DNA binding
BF28_RS03065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF28_RS03070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF28_RS03075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF28_RS03080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_RS03085	COG0512	Glutamine amidotransferase of anthranilate synthase
BF28_RS03090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF28_RS03095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_RS03110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF28_RS03115	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF28_RS03125	COG2208	phosphoserine phosphatase activity
BF28_RS03140	COG1098	S1 RNA binding domain
BF28_RS03160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF28_RS03165	COG3956	TIGRFAM MazG family protein
BF28_RS03170	COG2244	polysaccharide biosynthetic process
BF28_RS03175	COG2002	toxin-antitoxin pair type II binding
BF28_RS03180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF28_RS03210	COG0251	oxidation-reduction process
BF28_RS03215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF28_RS03230	COG4466	Protein conserved in bacteria
BF28_RS03245	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF28_RS03250	COG0084	hydrolase, TatD family'
BF28_RS03255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_RS03255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_RS03260	COG2002	toxin-antitoxin pair type II binding
BF28_RS03265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF28_RS03275	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF28_RS03285	COG1774	PSP1 C-terminal conserved region
BF28_RS03290	COG0470	DNA polymerase III
BF28_RS03300	COG1982	Orn Lys Arg decarboxylase major
BF28_RS03345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF28_RS03350	COG0590	tRNA wobble adenosine to inosine editing
BF28_RS03360	COG1335	isochorismatase
BF28_RS03365	COG1428	Deoxynucleoside kinase
BF28_RS03370	COG1428	Deoxynucleoside kinase
BF28_RS03400	COG1686	Belongs to the peptidase S11 family
BF28_RS03405	COG0517	IMP dehydrogenase activity
BF28_RS03405	COG0516	GMP reductase activity
BF28_RS03440	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF28_RS03445	COG0187	DNA topoisomerase II activity
BF28_RS03455	COG2501	S4 domain
BF28_RS03460	COG0592	DNA-directed DNA polymerase activity
BF28_RS03470	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BF28_RS03480	COG0706	membrane insertase activity
BF28_RS03485	COG1847	R3H domain protein
BF28_RS03510	COG1192	Involved in chromosome partitioning
BF28_RS03515	COG1475	DNA binding
BF28_RS03525	COG0668	transmembrane transport
BF28_RS03530	COG4481	Protein conserved in bacteria
BF28_RS03535	COG0012	GTP binding
BF28_RS03545	COG0629	single-stranded DNA binding
BF28_RS03555	COG4241	membrane
BF28_RS03560	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BF28_RS03570	COG0305	Participates in initiation and elongation during chromosome replication
BF28_RS03600	COG0745	RESPONSE REGULATOR receiver
BF28_RS03605	COG5002	protein histidine kinase activity
BF28_RS03610	COG4863	YycH protein
BF28_RS03615	COG4853	Protein conserved in bacteria
BF28_RS03620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF28_RS03625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF28_RS03655	COG1164	Oligoendopeptidase f
BF28_RS03680	COG1272	protein, Hemolysin III
BF28_RS03685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF28_RS03705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF28_RS03710	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BF28_RS03715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_RS03720	COG2814	Major facilitator Superfamily
BF28_RS03725	COG3275	phosphorelay sensor kinase activity
BF28_RS03730	COG3279	Response regulator of the LytR AlgR family
BF28_RS03745	COG0628	permease
BF28_RS03750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF28_RS03750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF28_RS03755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF28_RS03760	COG1309	transcriptional regulator
BF28_RS03765	COG0463	Glycosyl transferase, family 2
BF28_RS03785	COG0488	(ABC) transporter
BF28_RS03800	COG1607	acyl-coa hydrolase
BF28_RS03810	COG0840	transmembrane signaling receptor activity
BF28_RS03835	COG0477	Major facilitator Superfamily
BF28_RS03840	COG3279	Response regulator of the LytR AlgR family
BF28_RS03845	COG1966	Carbon starvation protein
BF28_RS03850	COG2879	small protein
BF28_RS03855	COG3706	GGDEF domain
BF28_RS03860	COG0351	phosphomethylpyrimidine kinase
BF28_RS03865	COG2203	Gaf domain
BF28_RS03865	COG4585	Histidine kinase
BF28_RS03870	COG2197	response regulator
BF28_RS03880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF28_RS03885	COG1011	Hydrolase
BF28_RS03890	COG2873	o-acetylhomoserine
BF28_RS03900	COG0460	homoserine dehydrogenase
BF28_RS03910	COG1609	Transcriptional regulator
BF28_RS03915	COG2755	lipolytic protein G-D-S-L family
BF28_RS03920	COG1131	(ABC) transporter
BF28_RS03925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF28_RS03935	COG2814	Major facilitator Superfamily
BF28_RS03940	COG0561	phosphatase activity
BF28_RS03945	COG2233	PERMEase
BF28_RS03950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF28_RS03960	COG2363	Small membrane protein
BF28_RS03970	COG3773	Cell wall hydrolase
BF28_RS03985	COG0280	phosphate acetyltransferase
BF28_RS03990	COG0095	Lipoate-protein ligase
BF28_RS04010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS04015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS04020	COG1120	ATPase activity
BF28_RS04025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS04030	COG1078	dGTPase activity
BF28_RS04040	COG1994	Peptidase M50
BF28_RS04050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_RS04055	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_RS04060	COG0789	Transcriptional regulator
BF28_RS04065	COG2814	Major facilitator Superfamily
BF28_RS04075	COG0010	Belongs to the arginase family
BF28_RS04095	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_RS04100	COG4506	Protein conserved in bacteria
BF28_RS04110	COG1595	DNA-templated transcription, initiation
BF28_RS04130	COG2234	aminopeptidase activity
BF28_RS04140	COG0024	Methionine aminopeptidase
BF28_RS04145	COG1131	(ABC) transporter
BF28_RS04150	COG0842	Transport permease protein
BF28_RS04155	COG4585	Histidine kinase
BF28_RS04160	COG2197	response regulator
BF28_RS04175	COG3300	MHYT domain
BF28_RS04175	COG5001	Diguanylate cyclase
BF28_RS04185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS04190	COG2181	nitrate reductase activity
BF28_RS04190	COG0247	lactate metabolic process
BF28_RS04195	COG0183	Belongs to the thiolase family
BF28_RS04200	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF28_RS04205	COG1960	acyl-CoA dehydrogenase activity
BF28_RS04210	COG1960	acyl-CoA dehydrogenase activity
BF28_RS04230	COG4821	SIS domain
BF28_RS04250	COG1494	fructose-1,6-bisphosphatase
BF28_RS04255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BF28_RS04275	COG2890	protein-(glutamine-N5) methyltransferase activity
BF28_RS04290	COG0009	L-threonylcarbamoyladenylate synthase
BF28_RS04310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF28_RS04315	COG2259	Doxx family
BF28_RS04320	COG2190	(PTS) system
BF28_RS04330	COG0698	ribose 5-phosphate isomerase
BF28_RS04365	COG0356	it plays a direct role in the translocation of protons across the membrane
BF28_RS04415	COG5001	Diguanylate cyclase
BF28_RS04415	COG3300	MHYT domain
BF28_RS04430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF28_RS04450	COG0839	Belongs to the complex I subunit 6 family
BF28_RS04460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF28_RS04465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF28_RS04470	COG1007	ATP synthesis coupled electron transport
BF28_RS04475	COG4836	Membrane
BF28_RS04490	COG2385	sporulation resulting in formation of a cellular spore
BF28_RS04495	COG3279	Response regulator of the LytR AlgR family
BF28_RS04510	COG0739	heme binding
BF28_RS04545	COG0726	polysaccharide deacetylase
BF28_RS04550	COG1609	Transcriptional regulator
BF28_RS04595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF28_RS04600	COG1682	transport, permease protein
BF28_RS04610	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF28_RS04630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF28_RS04635	COG0745	RESPONSE REGULATOR receiver
BF28_RS04640	COG5002	protein histidine kinase activity
BF28_RS04675	COG1136	(ABC) transporter
BF28_RS04680	COG0577	efflux transmembrane transporter activity
BF28_RS04725	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_RS04730	COG4715	Zinc finger, swim domain protein
BF28_RS04755	COG3584	3D domain protein
BF28_RS04755	COG1388	LysM domain
BF28_RS04760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_RS04770	COG1215	transferase activity, transferring glycosyl groups
BF28_RS04780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS04785	COG1388	LysM domain
BF28_RS04785	COG0791	NLP P60 protein
BF28_RS04795	COG1368	sulfuric ester hydrolase activity
BF28_RS04805	COG2389	metal-binding protein
BF28_RS04815	COG1620	l-lactate permease
BF28_RS04840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_RS04845	COG1294	oxidase, subunit
BF28_RS04850	COG1271	oxidase subunit
BF28_RS04860	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BF28_RS04865	COG0583	DNA-binding transcription factor activity
BF28_RS04870	COG1511	domain protein
BF28_RS04875	COG0346	lactoylglutathione lyase activity
BF28_RS04885	COG1301	dicarboxylic acid transport
BF28_RS04890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF28_RS04900	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF28_RS04910	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BF28_RS04920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF28_RS04925	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF28_RS04930	COG1486	melibiose metabolic process
BF28_RS04935	COG3394	polysaccharide catabolic process
BF28_RS04950	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BF28_RS04950	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BF28_RS04960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF28_RS04965	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BF28_RS04970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF28_RS04975	COG1316	TRANSCRIPTIONal
BF28_RS04980	COG1739	Uncharacterized protein family UPF0029
BF28_RS04985	COG1307	EDD domain protein, DegV family
BF28_RS04995	COG1733	regulation of RNA biosynthetic process
BF28_RS05000	COG1388	LysM domain
BF28_RS05000	COG0791	NLP P60 protein
BF28_RS05005	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BF28_RS05010	COG1040	competence protein
BF28_RS05015	COG1278	Cold shock
BF28_RS05020	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF28_RS05030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF28_RS05045	COG2884	Cell division ATP-binding protein ftsE
BF28_RS05050	COG2177	Part of the ABC transporter FtsEX involved in
BF28_RS05055	COG3409	Peptidoglycan-binding domain 1 protein
BF28_RS05055	COG0793	Belongs to the peptidase S41A family
BF28_RS05060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF28_RS05065	COG1132	(ABC) transporter
BF28_RS05075	COG0488	(ABC) transporter
BF28_RS05080	COG0655	NAD(P)H dehydrogenase (quinone) activity
BF28_RS05090	COG0583	DNA-binding transcription factor activity
BF28_RS05095	COG2855	membrane
BF28_RS05125	COG0789	Transcriptional regulator
BF28_RS05140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BF28_RS05150	COG1950	PFAM Membrane protein of
BF28_RS05170	COG0110	maltose O-acetyltransferase activity
BF28_RS05175	COG0457	Tetratricopeptide repeat
BF28_RS05180	COG0492	ferredoxin-NADP+ reductase activity
BF28_RS05190	COG1051	belongs to the nudix hydrolase family
BF28_RS05200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BF28_RS05210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_RS05220	COG2323	membrane
BF28_RS05235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_RS05265	COG0457	Tetratricopeptide repeat
BF28_RS05285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BF28_RS05300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF28_RS05335	COG1346	cytolysis
BF28_RS05340	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BF28_RS05345	COG1647	Serine aminopeptidase, S33
BF28_RS05350	COG0557	exoribonuclease II activity
BF28_RS05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS05440	COG3290	protein histidine kinase activity
BF28_RS05440	COG0840	transmembrane signaling receptor activity
BF28_RS05460	COG1252	NADH dehydrogenase
BF28_RS05470	COG1733	regulation of RNA biosynthetic process
BF28_RS05475	COG2814	Major facilitator Superfamily
BF28_RS05480	COG0656	L-ascorbic acid biosynthetic process
BF28_RS05495	COG2910	NAD(P)H-binding
BF28_RS05500	COG1115	amino acid carrier protein
BF28_RS05505	COG1115	amino acid carrier protein
BF28_RS05510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS05515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS05535	COG1611	Belongs to the LOG family
BF28_RS05550	COG0783	Belongs to the Dps family
BF28_RS05555	COG1115	amino acid carrier protein
BF28_RS05565	COG0490	domain, Protein
BF28_RS05570	COG0475	glutathione-regulated potassium exporter activity
BF28_RS05585	COG1741	Belongs to the pirin family
BF28_RS05590	COG3227	Zinc metalloprotease (Elastase)
BF28_RS05595	COG2151	metal-sulfur cluster biosynthetic enzyme
BF28_RS05600	COG0840	transmembrane signaling receptor activity
BF28_RS05625	COG5002	protein histidine kinase activity
BF28_RS05630	COG0745	RESPONSE REGULATOR receiver
BF28_RS05635	COG1376	ErfK ybiS ycfS ynhG family protein
BF28_RS05645	COG0586	Pfam SNARE associated Golgi protein
BF28_RS05675	COG1131	(ABC) transporter
BF28_RS05685	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF28_RS05690	COG0745	RESPONSE REGULATOR receiver
BF28_RS05695	COG5002	protein histidine kinase activity
BF28_RS05710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS05720	COG0706	membrane insertase activity
BF28_RS05735	COG0531	amino acid
BF28_RS05740	COG2814	Major facilitator Superfamily
BF28_RS05760	COG0840	transmembrane signaling receptor activity
BF28_RS05765	COG0011	TIGRFAM Protein of
BF28_RS05780	COG1686	Belongs to the peptidase S11 family
BF28_RS05790	COG1024	Enoyl-CoA hydratase
BF28_RS05790	COG1250	3-hydroxyacyl-CoA dehydrogenase
BF28_RS05795	COG0183	Belongs to the thiolase family
BF28_RS05800	COG1960	acyl-CoA dehydrogenase activity
BF28_RS05805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS05810	COG1309	transcriptional regulator
BF28_RS05815	COG1396	sequence-specific DNA binding
BF28_RS05870	COG1393	Belongs to the ArsC family
BF28_RS05880	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BF28_RS05885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_RS05905	COG2011	ABC-type metal ion transport system permease component
BF28_RS05910	COG1464	Belongs to the NlpA lipoprotein family
BF28_RS05915	COG1464	Belongs to the NlpA lipoprotein family
BF28_RS05920	COG0396	ATPase activity
BF28_RS05925	COG0719	Fe-S assembly protein
BF28_RS05930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF28_RS05935	COG0822	iron-sulfur transferase activity
BF28_RS05940	COG0719	Fe-S assembly protein
BF28_RS05945	COG0737	Belongs to the 5'-nucleotidase family
BF28_RS05950	COG3377	Domain of unknown function (DUF1805)
BF28_RS05960	COG0739	heme binding
BF28_RS05985	COG4377	Putative membrane peptidase family (DUF2324)
BF28_RS05990	COG0789	Transcriptional regulator
BF28_RS06000	COG4470	Protein conserved in bacteria
BF28_RS06020	COG1494	fructose-1,6-bisphosphatase
BF28_RS06025	COG2445	Protein of unknown function DUF86
BF28_RS06035	COG0647	UMP catabolic process
BF28_RS06045	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_RS06060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BF28_RS06065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF28_RS06075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BF28_RS06080	COG4837	Protein of unknown function (DUF1462)
BF28_RS06095	COG2824	Alkylphosphonate utilization operon protein PhnA
BF28_RS06100	COG0390	transport system, permease component
BF28_RS06105	COG2274	protein secretion by the type I secretion system
BF28_RS06115	COG1252	NADH dehydrogenase
BF28_RS06130	COG0316	Belongs to the HesB IscA family
BF28_RS06150	COG1683	Conserved Protein
BF28_RS06165	COG3708	Transcriptional regulator
BF28_RS06180	COG1252	NADH dehydrogenase
BF28_RS06195	COG3584	3D domain protein
BF28_RS06210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF28_RS06215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BF28_RS06220	COG1268	BioY protein
BF28_RS06230	COG2050	protein possibly involved in aromatic compounds catabolism
BF28_RS06250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_RS06255	COG5018	Exonuclease
BF28_RS06275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF28_RS06285	COG2267	carboxylic ester hydrolase activity
BF28_RS06290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF28_RS06295	COG1522	sequence-specific DNA binding
BF28_RS06300	COG0436	Aminotransferase
BF28_RS06305	COG1098	S1 RNA binding domain
BF28_RS06310	COG2155	Conserved Protein
BF28_RS06330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF28_RS06335	COG1285	pathogenesis
BF28_RS06370	COG0544	peptidyl-prolyl cis-trans isomerase activity
BF28_RS06490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF28_RS06500	COG0058	SHG alpha-glucan phosphorylase activity
BF28_RS06525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BF28_RS06530	COG1575	Belongs to the MenA family. Type 1 subfamily
BF28_RS06535	COG1169	isochorismate synthase
BF28_RS06545	COG0596	Alpha beta hydrolase
BF28_RS06550	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BF28_RS06560	COG4948	Mandelate Racemase Muconate Lactonizing
BF28_RS06580	COG0590	tRNA wobble adenosine to inosine editing
BF28_RS06585	COG2233	PERMEase
BF28_RS06590	COG0583	DNA-binding transcription factor activity
BF28_RS06595	COG3964	amidohydrolase
BF28_RS06615	COG2188	Transcriptional regulator
BF28_RS06630	COG0577	efflux transmembrane transporter activity
BF28_RS06635	COG1136	(ABC) transporter
BF28_RS06640	COG0577	efflux transmembrane transporter activity
BF28_RS06645	COG0577	efflux transmembrane transporter activity
BF28_RS06650	COG2205	protein histidine kinase activity
BF28_RS06655	COG0745	RESPONSE REGULATOR receiver
BF28_RS06660	COG0640	Transcriptional regulator
BF28_RS06665	COG5658	integral membrane protein
BF28_RS06670	COG1131	(ABC) transporter
BF28_RS06680	COG2207	Transcriptional regulator
BF28_RS06680	COG3708	Transcriptional regulator
BF28_RS06685	COG1136	(ABC) transporter
BF28_RS06690	COG0577	efflux transmembrane transporter activity
BF28_RS06700	COG4977	sequence-specific DNA binding
BF28_RS06710	COG0586	Pfam SNARE associated Golgi protein
BF28_RS06735	COG1597	lipid kinase activity
BF28_RS06740	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF28_RS06765	COG0745	RESPONSE REGULATOR receiver
BF28_RS06770	COG5002	protein histidine kinase activity
BF28_RS06800	COG1842	Phage shock protein A
BF28_RS06825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS06845	COG1294	oxidase, subunit
BF28_RS06850	COG1271	oxidase subunit
BF28_RS06855	COG0288	reversible hydration of carbon dioxide
BF28_RS06885	COG0494	nUDIX hydrolase
BF28_RS06910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_RS06915	COG1116	anion transmembrane transporter activity
BF28_RS06920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF28_RS06935	COG1368	sulfuric ester hydrolase activity
BF28_RS06940	COG2267	carboxylic ester hydrolase activity
BF28_RS06945	COG4191	Histidine kinase
BF28_RS06950	COG5002	protein histidine kinase activity
BF28_RS06960	COG1349	DNA-binding transcription factor activity
BF28_RS06965	COG0546	phosphoglycolate phosphatase activity
BF28_RS06970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF28_RS07015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS07030	COG0521	Mo-molybdopterin cofactor biosynthetic process
BF28_RS07040	COG0438	transferase activity, transferring glycosyl groups
BF28_RS07045	COG0671	phosphoesterase, PA-phosphatase related
BF28_RS07050	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF28_RS07055	COG2267	carboxylic ester hydrolase activity
BF28_RS07080	COG5504	Zn-dependent protease
BF28_RS07090	COG1794	racemase activity, acting on amino acids and derivatives
BF28_RS07100	COG1131	(ABC) transporter
BF28_RS07105	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BF28_RS07110	COG1242	4 iron, 4 sulfur cluster binding
BF28_RS07130	COG1136	(ABC) transporter
BF28_RS07145	COG0582	viral genome integration into host DNA
BF28_RS07150	COG0490	domain, Protein
BF28_RS07155	COG0475	glutathione-regulated potassium exporter activity
BF28_RS07160	COG2814	Major facilitator Superfamily
BF28_RS07205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BF28_RS07215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_RS07235	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF28_RS07240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_RS07250	COG0303	'Molybdopterin
BF28_RS07255	COG1763	Mo-molybdopterin cofactor biosynthetic process
BF28_RS07260	COG0314	molybdopterin synthase activity
BF28_RS07285	COG1329	Transcriptional regulator
BF28_RS07305	COG3832	glyoxalase III activity
BF28_RS07315	COG2814	Major facilitator Superfamily
BF28_RS07320	COG2081	HI0933 family
BF28_RS07325	COG2244	polysaccharide biosynthetic process
BF28_RS07330	COG1187	pseudouridine synthase activity
BF28_RS07335	COG1349	DNA-binding transcription factor activity
BF28_RS07340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF28_RS07355	COG1523	belongs to the glycosyl hydrolase 13 family
BF28_RS07360	COG0510	thiamine kinase activity
BF28_RS07375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS07385	COG1363	Peptidase, m42
BF28_RS07390	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BF28_RS07395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_RS07405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_RS07415	COG1674	ftsk spoiiie
BF28_RS07435	COG1695	Transcriptional regulator
BF28_RS07440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS07460	COG2309	aminopeptidase activity
BF28_RS07470	COG3118	belongs to the thioredoxin family
BF28_RS07475	COG4851	CamS sex pheromone cAM373 precursor
BF28_RS07490	COG1609	Transcriptional regulator
BF28_RS07525	COG0666	response to abiotic stimulus
BF28_RS07535	COG0745	RESPONSE REGULATOR receiver
BF28_RS07545	COG2267	carboxylic ester hydrolase activity
BF28_RS07550	COG0123	including yeast histone deacetylase and acetoin utilization protein
BF28_RS07555	COG0517	IMP dehydrogenase activity
BF28_RS07560	COG0454	-acetyltransferase
BF28_RS07565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF28_RS07575	COG1595	DNA-templated transcription, initiation
BF28_RS07640	COG0626	cystathionine gamma-synthase activity
BF28_RS07645	COG1956	GAF domain-containing protein
BF28_RS07650	COG1309	transcriptional regulator
BF28_RS07655	COG0697	spore germination
BF28_RS07660	COG0583	DNA-binding transcription factor activity
BF28_RS07670	COG1104	cysteine desulfurase activity
BF28_RS07685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF28_RS07695	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BF28_RS07710	COG3874	Sporulation protein YtfJ
BF28_RS07715	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF28_RS07720	COG0827	DNA restriction-modification system
BF28_RS07740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS07780	COG0589	response to stress
BF28_RS07785	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS07800	COG1476	TRANSCRIPTIONal
BF28_RS07810	COG0662	Cupin 2, conserved barrel domain protein
BF28_RS07850	COG0006	proline dipeptidase activity
BF28_RS07865	COG4109	DRTGG domain
BF28_RS07875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF28_RS07890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF28_RS07905	COG0587	DNA-directed DNA polymerase activity
BF28_RS07910	COG0281	malic enzyme
BF28_RS07915	COG1725	Transcriptional regulator
BF28_RS07940	COG3030	protein affecting phage T7 exclusion by the F plasmid
BF28_RS07945	COG0628	permease
BF28_RS07960	COG0372	Belongs to the citrate synthase family
BF28_RS07965	COG0538	isocitrate dehydrogenase activity
BF28_RS07985	COG0745	RESPONSE REGULATOR receiver
BF28_RS07990	COG5002	protein histidine kinase activity
BF28_RS07995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF28_RS07995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF28_RS08005	COG1971	Probably functions as a manganese efflux pump
BF28_RS08015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BF28_RS08025	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BF28_RS08035	COG3611	Membrane attachment protein
BF28_RS08040	COG1484	DNA-dependent DNA replication
BF28_RS08050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF28_RS08075	COG1363	Peptidase, m42
BF28_RS08080	COG1309	transcriptional regulator
BF28_RS08085	COG1566	PFAM secretion protein HlyD family protein
BF28_RS08090	COG2814	Major facilitator Superfamily
BF28_RS08105	COG1418	mRNA catabolic process
BF28_RS08115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF28_RS08160	COG1286	toxin biosynthetic process
BF28_RS08165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF28_RS08165	COG1796	DNA polymerase
BF28_RS08180	COG1187	pseudouridine synthase activity
BF28_RS08185	COG1114	Component of the transport system for branched-chain amino acids
BF28_RS08190	COG5386	Cell surface protein
BF28_RS08195	COG5386	Cell surface protein
BF28_RS08210	COG1120	ATPase activity
BF28_RS08215	COG4509	Sortase family
BF28_RS08230	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF28_RS08235	COG4895	conserved protein (DUF2196)
BF28_RS08245	COG0745	RESPONSE REGULATOR receiver
BF28_RS08250	COG2205	protein histidine kinase activity
BF28_RS08255	COG1131	(ABC) transporter
BF28_RS08280	COG2318	DinB family
BF28_RS08295	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS08300	COG1309	transcriptional regulator
BF28_RS08305	COG1024	Enoyl-CoA hydratase
BF28_RS08310	COG2086	electron transfer activity
BF28_RS08315	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF28_RS08320	COG3118	belongs to the thioredoxin family
BF28_RS08330	COG1719	4-vinyl reductase, 4VR
BF28_RS08335	COG2009	succinate dehydrogenase
BF28_RS08340	COG1053	succinate dehydrogenase
BF28_RS08345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF28_RS08350	COG0824	Thioesterase
BF28_RS08355	COG1876	peptidase activity
BF28_RS08360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF28_RS08365	COG1360	Flagellar Motor Protein
BF28_RS08370	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BF28_RS08375	COG4152	abc transporter atp-binding protein
BF28_RS08380	COG1668	transmembrane transport
BF28_RS08385	COG1959	2 iron, 2 sulfur cluster binding
BF28_RS08395	COG0697	spore germination
BF28_RS08400	COG1396	sequence-specific DNA binding
BF28_RS08405	COG1983	PspC domain protein
BF28_RS08415	COG3279	Response regulator of the LytR AlgR family
BF28_RS08420	COG3275	phosphorelay sensor kinase activity
BF28_RS08425	COG4608	Belongs to the ABC transporter superfamily
BF28_RS08430	COG0444	Belongs to the ABC transporter superfamily
BF28_RS08440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_RS08450	COG0402	S-adenosylhomocysteine deaminase activity
BF28_RS08455	COG0402	S-adenosylhomocysteine deaminase activity
BF28_RS08465	COG2233	PERMEase
BF28_RS08470	COG2197	response regulator
BF28_RS08485	COG5401	PFAM Sporulation and spore germination
BF28_RS08500	COG0622	Phosphoesterase
BF28_RS08515	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BF28_RS08600	COG0470	DNA polymerase III
BF28_RS08600	COG1067	ATP-dependent peptidase activity
BF28_RS08615	COG1764	response to oxidative stress
BF28_RS08620	COG1846	Transcriptional regulator
BF28_RS08630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF28_RS08640	COG1587	Uroporphyrinogen-III synthase
BF28_RS08645	COG0113	porphobilinogen synthase activity
BF28_RS08655	COG1388	LysM domain
BF28_RS08670	COG0285	dihydrofolate synthase activity
BF28_RS08690	COG1077	Cell shape determining protein MreB Mrl
BF28_RS08710	COG2894	cell division
BF28_RS08715	COG0739	heme binding
BF28_RS08720	COG1994	Peptidase M50
BF28_RS08725	COG1530	ribonuclease E activity
BF28_RS08735	COG2868	ribosomal protein
BF28_RS08745	COG3290	protein histidine kinase activity
BF28_RS08755	COG0745	RESPONSE REGULATOR receiver
BF28_RS08760	COG5002	protein histidine kinase activity
BF28_RS08765	COG1136	(ABC) transporter
BF28_RS08770	COG0577	efflux transmembrane transporter activity
BF28_RS08775	COG0577	efflux transmembrane transporter activity
BF28_RS08780	COG0077	Prephenate dehydratase
BF28_RS08785	COG2258	MOSC domain
BF28_RS08790	COG1827	regulation of RNA biosynthetic process
BF28_RS08795	COG1104	cysteine desulfurase activity
BF28_RS08800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF28_RS08805	COG0157	Belongs to the NadC ModD family
BF28_RS08830	COG0640	Transcriptional regulator
BF28_RS08835	COG0697	spore germination
BF28_RS08845	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF28_RS08875	COG1862	Preprotein translocase
BF28_RS08885	COG2323	membrane
BF28_RS08890	COG2244	polysaccharide biosynthetic process
BF28_RS08900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF28_RS08900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF28_RS08905	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF28_RS08910	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF28_RS08910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF28_RS08920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF28_RS08950	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF28_RS08960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF28_RS08965	COG1959	2 iron, 2 sulfur cluster binding
BF28_RS08970	COG1104	cysteine desulfurase activity
BF28_RS08985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF28_RS09005	COG0628	permease
BF28_RS09035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF28_RS09040	COG4122	O-methyltransferase activity
BF28_RS09045	COG0826	peptidase U32
BF28_RS09050	COG0826	peptidase U32
BF28_RS09065	COG0768	penicillin binding
BF28_RS09090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_RS09095	COG0626	cystathionine gamma-synthase activity
BF28_RS09100	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS09100	COG1454	alcohol dehydrogenase
BF28_RS09110	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BF28_RS09150	COG2259	Doxx family
BF28_RS09155	COG2514	catechol 2,3-dioxygenase activity
BF28_RS09165	COG3186	Phenylalanine-4-hydroxylase
BF28_RS09170	COG1404	Belongs to the peptidase S8 family
BF28_RS09205	COG2267	carboxylic ester hydrolase activity
BF28_RS09215	COG1785	Belongs to the alkaline phosphatase family
BF28_RS09225	COG2357	RelA SpoT domain protein
BF28_RS09230	COG0778	Nitroreductase
BF28_RS09240	COG1595	DNA-templated transcription, initiation
BF28_RS09275	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BF28_RS09280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BF28_RS09290	COG1534	Rna-binding protein
BF28_RS09300	COG1713	HD superfamily hydrolase involved in NAD metabolism
BF28_RS09305	COG0799	negative regulation of ribosome biogenesis
BF28_RS09310	COG2226	methyltransferase
BF28_RS09315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_RS09320	COG1596	polysaccharide export
BF28_RS09320	COG1555	photosystem II stabilization
BF28_RS09325	COG2131	deaminase
BF28_RS09330	COG2333	competence protein COMEC
BF28_RS09330	COG0658	competence protein
BF28_RS09340	COG1466	dna polymerase III delta subunit
BF28_RS09365	COG1733	regulation of RNA biosynthetic process
BF28_RS09370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF28_RS09400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BF28_RS09405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF28_RS09410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BF28_RS09415	COG1610	YqeY-like protein
BF28_RS09435	COG1702	phosphate starvation-inducible protein PhoH
BF28_RS09440	COG1480	7TM receptor with intracellular HD hydrolase
BF28_RS09450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BF28_RS09455	COG0295	cytidine deaminase activity
BF28_RS09460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF28_RS09475	COG0517	IMP dehydrogenase activity
BF28_RS09495	COG0358	DNA primase activity
BF28_RS09500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF28_RS09505	COG2010	Cytochrome c
BF28_RS09510	COG2384	SAM-dependent methyltransferase
BF28_RS09515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF28_RS09545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS09550	COG1121	(ABC) transporter
BF28_RS09555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF28_RS09560	COG0735	belongs to the Fur family
BF28_RS09585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF28_RS09590	COG0477	Major facilitator Superfamily
BF28_RS09595	COG0768	penicillin binding
BF28_RS09600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF28_RS09605	COG0573	inorganic phosphate transmembrane transporter activity
BF28_RS09610	COG0581	inorganic phosphate transmembrane transporter activity
BF28_RS09620	COG0704	Plays a role in the regulation of phosphate uptake
BF28_RS09625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF28_RS09630	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF28_RS09635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF28_RS09640	COG4483	Protein conserved in bacteria
BF28_RS09645	COG1940	carbohydrate kinase activity
BF28_RS09655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS09675	COG0626	cystathionine gamma-synthase activity
BF28_RS09680	COG0626	cystathionine gamma-synthase activity
BF28_RS09690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF28_RS09690	COG0646	methionine synthase
BF28_RS09695	COG1410	methionine synthase
BF28_RS09695	COG0646	methionine synthase
BF28_RS09745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BF28_RS09750	COG1459	type II secretion system
BF28_RS09760	COG4970	Tfp pilus assembly protein FimT
BF28_RS09815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_RS09845	COG1725	Transcriptional regulator
BF28_RS09850	COG1131	(ABC) transporter
BF28_RS09890	COG2076	Multidrug Resistance protein
BF28_RS09895	COG2076	Multidrug Resistance protein
BF28_RS09905	COG1609	Transcriptional regulator
BF28_RS09915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_RS09920	COG0095	Lipoate-protein ligase
BF28_RS09950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF28_RS09960	COG3872	metal-dependent enzyme
BF28_RS09975	COG0006	proline dipeptidase activity
BF28_RS10000	COG3854	ATPases associated with a variety of cellular activities
BF28_RS10045	COG0511	ligase activity, forming carbon-carbon bonds
BF28_RS10050	COG0439	Biotin carboxylase
BF28_RS10055	COG1302	Protein conserved in bacteria
BF28_RS10080	COG0142	geranyltranstransferase activity
BF28_RS10090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BF28_RS10100	COG0497	DNA recombination
BF28_RS10105	COG0750	zinc metalloprotease
BF28_RS10110	COG0745	RESPONSE REGULATOR receiver
BF28_RS10135	COG3093	addiction module antidote protein HigA
BF28_RS10140	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_RS10150	COG3829	transcription factor binding
BF28_RS10150	COG3290	protein histidine kinase activity
BF28_RS10160	COG0280	phosphate acetyltransferase
BF28_RS10175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF28_RS10180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF28_RS10185	COG0022	dehydrogenase e1 component
BF28_RS10190	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF28_RS10200	COG0772	Belongs to the SEDS family
BF28_RS10205	COG2323	membrane
BF28_RS10230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_RS10235	COG0765	amino acid transport
BF28_RS10240	COG1126	abc transporter atp-binding protein
BF28_RS10245	COG4129	membrane
BF28_RS10250	COG1376	ErfK ybiS ycfS ynhG family protein
BF28_RS10265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS10270	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF28_RS10300	COG1760	l-serine dehydratase
BF28_RS10305	COG1760	l-serine dehydratase
BF28_RS10310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_RS10315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS10320	COG0300	oxidoreductase activity
BF28_RS10345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF28_RS10365	COG1522	sequence-specific DNA binding
BF28_RS10375	COG0737	Belongs to the 5'-nucleotidase family
BF28_RS10380	COG1757	Na H antiporter
BF28_RS10390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF28_RS10405	COG2226	methyltransferase
BF28_RS10405	COG1073	alpha beta
BF28_RS10410	COG4106	trans-aconitate 2-methyltransferase activity
BF28_RS10435	COG0307	riboflavin synthase, alpha
BF28_RS10440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_RS10440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_RS10455	COG1073	alpha beta
BF28_RS10460	COG0456	acetyltransferase
BF28_RS10465	COG1609	Transcriptional regulator
BF28_RS10470	COG2056	Na+-H+ antiporter family
BF28_RS10475	COG0596	Alpha beta hydrolase
BF28_RS10485	COG4085	toxin activity
BF28_RS10485	COG1525	nuclease
BF28_RS10485	COG0737	Belongs to the 5'-nucleotidase family
BF28_RS10495	COG0456	acetyltransferase
BF28_RS10495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF28_RS10500	COG0656	L-ascorbic acid biosynthetic process
BF28_RS10505	COG0667	Aldo Keto reductase
BF28_RS10525	COG1300	Membrane
BF28_RS10530	COG0735	belongs to the Fur family
BF28_RS10540	COG4974	Belongs to the 'phage' integrase family
BF28_RS10565	COG0598	Magnesium transport protein CorA
BF28_RS10580	COG1846	Transcriptional regulator
BF28_RS10605	COG1131	(ABC) transporter
BF28_RS10610	COG1725	Transcriptional regulator
BF28_RS10615	COG1686	Belongs to the peptidase S11 family
BF28_RS10635	COG0733	neurotransmitter:sodium symporter activity
BF28_RS10660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_RS10675	COG0697	spore germination
BF28_RS10680	COG0561	phosphatase activity
BF28_RS10685	COG4086	secreted protein
BF28_RS10690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BF28_RS10700	COG0456	acetyltransferase
BF28_RS10705	COG1547	Domain of unknown function (DUF309)
BF28_RS10735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF28_RS10745	COG2188	Transcriptional regulator
BF28_RS10755	COG3711	transcriptional antiterminator
BF28_RS10760	COG2190	(PTS) system
BF28_RS10760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_RS10760	COG1263	PTS System
BF28_RS10785	COG0778	Nitroreductase
BF28_RS10790	COG2199	diguanylate cyclase activity
BF28_RS10795	COG2084	Dehydrogenase
BF28_RS10830	COG0436	Aminotransferase
BF28_RS10835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF28_RS10855	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS10860	COG1695	Transcriptional regulator
BF28_RS10900	COG0183	Belongs to the thiolase family
BF28_RS10940	COG3842	ATPase activity
BF28_RS10945	COG0366	Alpha amylase catalytic
BF28_RS10955	COG2182	Extracellular solute-binding protein
BF28_RS10960	COG1175	transmembrane transport
BF28_RS10965	COG3833	ABC-type maltose transport systems, permease component
BF28_RS10970	COG1609	Transcriptional regulator
BF28_RS10975	COG0436	Aminotransferase
BF28_RS10985	COG2205	protein histidine kinase activity
BF28_RS10995	COG3209	COG3209 Rhs family protein
BF28_RS11020	COG2814	Major facilitator Superfamily
BF28_RS11060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF28_RS11070	COG1408	metallophosphoesterase
BF28_RS11075	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS11080	COG2200	EAL domain
BF28_RS11095	COG4703	Protein of unknown function (DUF1797)
BF28_RS11105	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BF28_RS11115	COG0517	IMP dehydrogenase activity
BF28_RS11120	COG0583	DNA-binding transcription factor activity
BF28_RS11140	COG0569	domain protein
BF28_RS11145	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF28_RS11155	COG0561	phosphatase activity
BF28_RS11160	COG0242	peptide deformylase activity
BF28_RS11170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF28_RS11175	COG0022	dehydrogenase e1 component
BF28_RS11225	COG1982	Orn Lys Arg decarboxylase major
BF28_RS11245	COG0483	inositol monophosphate 1-phosphatase activity
BF28_RS11255	COG1217	gtp-binding protein TYPA
BF28_RS11270	COG4896	Protein conserved in bacteria
BF28_RS11280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF28_RS11285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BF28_RS11295	COG0772	Belongs to the SEDS family
BF28_RS11300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BF28_RS11335	COG3336	cytochrome c oxidase
BF28_RS11350	COG2340	Cysteine-rich secretory protein family
BF28_RS11365	COG0406	alpha-ribazole phosphatase activity
BF28_RS11370	COG3679	Belongs to the UPF0342 family
BF28_RS11385	COG0742	ribosomal rna small subunit methyltransferase
BF28_RS11395	COG3314	Sporulation integral membrane protein YlbJ
BF28_RS11400	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF28_RS11405	COG3480	Lon protease (S16) C-terminal proteolytic domain
BF28_RS11415	COG1399	metal-binding, possibly nucleic acid-binding protein
BF28_RS11420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BF28_RS11435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF28_RS11450	COG4839	cell division protein FtsL
BF28_RS11455	COG0768	penicillin binding
BF28_RS11460	COG0768	penicillin binding
BF28_RS11465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF28_RS11480	COG0772	Belongs to the SEDS family
BF28_RS11495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BF28_RS11500	COG0849	cell division
BF28_RS11505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF28_RS11515	COG1191	sigma factor activity
BF28_RS11520	COG1191	sigma factor activity
BF28_RS11525	COG1873	PFAM PRC-barrel domain
BF28_RS11530	COG1496	oxidoreductase activity
BF28_RS11535	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF28_RS11545	COG0762	integral membrane protein
BF28_RS11550	COG2302	S4 RNA-binding domain
BF28_RS11555	COG3599	regulation of cell shape
BF28_RS11575	COG0564	pseudouridine synthase activity
BF28_RS11635	COG3069	C4-dicarboxylate transmembrane transporter activity
BF28_RS11655	COG0006	proline dipeptidase activity
BF28_RS11665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF28_RS11670	COG1561	YicC-like family, N-terminal region
BF28_RS11690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF28_RS11695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF28_RS11700	COG0242	peptide deformylase activity
BF28_RS11710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BF28_RS11710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF28_RS11720	COG0631	protein serine/threonine phosphatase activity
BF28_RS11725	COG2815	serine threonine protein kinase
BF28_RS11725	COG0515	serine threonine protein kinase
BF28_RS11735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF28_RS11740	COG1564	THIamine pyrophosphokinase
BF28_RS11755	COG1302	Protein conserved in bacteria
BF28_RS11760	COG1461	Dihydroxyacetone kinase
BF28_RS11765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF28_RS11780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF28_RS11785	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS11790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF28_RS11800	COG1196	nuclear chromosome segregation
BF28_RS11805	COG0552	protein localization to endoplasmic reticulum
BF28_RS11815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF28_RS11825	COG1837	Belongs to the UPF0109 family
BF28_RS11865	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF28_RS11870	COG0758	DNA mediated transformation
BF28_RS11875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF28_RS11885	COG4974	Belongs to the 'phage' integrase family
BF28_RS11915	COG0528	UMP kinase activity
BF28_RS11930	COG4589	Belongs to the CDS family
BF28_RS11940	COG0750	zinc metalloprotease
BF28_RS11960	COG0195	Participates in both transcription termination and antitermination
BF28_RS11965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BF28_RS11970	COG1358	cellular component organization or biogenesis
BF28_RS11980	COG1550	Protein conserved in bacteria
BF28_RS11995	COG0196	riboflavin kinase activity
BF28_RS12010	COG0726	polysaccharide deacetylase
BF28_RS12015	COG0612	Peptidase, M16
BF28_RS12020	COG1873	PFAM PRC-barrel domain
BF28_RS12025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF28_RS12030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BF28_RS12035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF28_RS12040	COG0527	aspartate kinase activity
BF28_RS12055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF28_RS12060	COG0740	serine-type endopeptidase activity
BF28_RS12070	COG1674	ftsk spoiiie
BF28_RS12075	COG2188	Transcriptional regulator
BF28_RS12080	COG1744	ABC transporter substrate-binding protein PnrA-like
BF28_RS12085	COG3845	ABC transporter
BF28_RS12090	COG4603	Belongs to the binding-protein-dependent transport system permease family
BF28_RS12095	COG1079	Belongs to the binding-protein-dependent transport system permease family
BF28_RS12100	COG0612	Peptidase, M16
BF28_RS12105	COG0612	Peptidase, M16
BF28_RS12110	COG0300	oxidoreductase activity
BF28_RS12125	COG1426	Protein conserved in bacteria
BF28_RS12130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BF28_RS12155	COG1692	metallophosphoesterase
BF28_RS12160	COG2359	stage V sporulation protein S
BF28_RS12170	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF28_RS12170	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF28_RS12175	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF28_RS12185	COG4550	Control of competence regulator ComK, YlbF/YmcA
BF28_RS12205	COG0640	Transcriptional regulator
BF28_RS12215	COG2814	Major facilitator Superfamily
BF28_RS12220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF28_RS12250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF28_RS12255	COG1368	sulfuric ester hydrolase activity
BF28_RS12260	COG0562	UDP-galactopyranose mutase
BF28_RS12265	COG3773	Cell wall hydrolase
BF28_RS12270	COG1404	Belongs to the peptidase S8 family
BF28_RS12285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS12290	COG1380	Effector of murein hydrolase LrgA
BF28_RS12310	COG3300	MHYT domain
BF28_RS12310	COG5001	Diguanylate cyclase
BF28_RS12315	COG0346	lactoylglutathione lyase activity
BF28_RS12335	COG2364	Membrane
BF28_RS12345	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF28_RS12350	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF28_RS12355	COG2169	Transcriptional regulator
BF28_RS12360	COG0708	Exodeoxyribonuclease III
BF28_RS12365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS12370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS12375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS12380	COG1120	ATPase activity
BF28_RS12385	COG2819	hydrolase of the alpha beta superfamily
BF28_RS12395	COG1937	Protein conserved in bacteria
BF28_RS12400	COG2608	mercury ion transmembrane transporter activity
BF28_RS12405	COG2217	Heavy metal translocating P-type atpase
BF28_RS12415	COG2116	formate transmembrane transporter activity
BF28_RS12420	COG1408	metallophosphoesterase
BF28_RS12430	COG1113	amino acid transport
BF28_RS12445	COG2322	membrane
BF28_RS12450	COG1979	alcohol dehydrogenase
BF28_RS12455	COG1349	DNA-binding transcription factor activity
BF28_RS12460	COG1105	Belongs to the carbohydrate kinase PfkB family
BF28_RS12465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF28_RS12465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_RS12465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BF28_RS12470	COG3584	3D domain protein
BF28_RS12470	COG1388	LysM domain
BF28_RS12500	COG0464	growth
BF28_RS12510	COG2860	membrane
BF28_RS12515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF28_RS12520	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BF28_RS12525	COG0789	Transcriptional regulator
BF28_RS12530	COG0174	glutamine synthetase
BF28_RS12660	COG1595	DNA-templated transcription, initiation
BF28_RS12830	COG1122	ATPase activity
BF28_RS12860	COG1695	Transcriptional regulator
BF28_RS12880	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BF28_RS12890	COG0737	Belongs to the 5'-nucleotidase family
BF28_RS12905	COG3639	organic phosphonate transmembrane transporter activity
BF28_RS12930	COG1132	(ABC) transporter
BF28_RS12935	COG1132	(ABC) transporter
BF28_RS12960	COG0730	response to heat
BF28_RS12975	COG1346	cytolysis
BF28_RS12985	COG0583	DNA-binding transcription factor activity
BF28_RS12995	COG1131	(ABC) transporter
BF28_RS13015	COG0785	Cytochrome C biogenesis protein
BF28_RS13020	COG4846	Membrane protein involved in cytochrome C biogenesis
BF28_RS13065	COG2226	methyltransferase
BF28_RS13090	COG0010	Belongs to the arginase family
BF28_RS13095	COG1329	Transcriptional regulator
BF28_RS13100	COG1902	pentaerythritol trinitrate reductase activity
BF28_RS13105	COG0069	glutamate synthase activity
BF28_RS13110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_RS13115	COG0346	lactoylglutathione lyase activity
BF28_RS13120	COG0400	carboxylic ester hydrolase activity
BF28_RS13125	COG5002	protein histidine kinase activity
BF28_RS13135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS13180	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS13185	COG1268	BioY protein
BF28_RS13190	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS13195	COG0183	Belongs to the thiolase family
BF28_RS13210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF28_RS13220	COG2211	Major facilitator Superfamily
BF28_RS13250	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BF28_RS13255	COG1132	(ABC) transporter
BF28_RS13265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_RS13295	COG0824	Thioesterase
BF28_RS13300	COG4841	protein insertion into membrane
BF28_RS13320	COG0745	RESPONSE REGULATOR receiver
BF28_RS13325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF28_RS13330	COG1832	CoA-binding protein
BF28_RS13340	COG0187	DNA topoisomerase II activity
BF28_RS13345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BF28_RS13350	COG0673	inositol 2-dehydrogenase activity
BF28_RS13360	COG1131	(ABC) transporter
BF28_RS13375	COG1595	DNA-templated transcription, initiation
BF28_RS13385	COG1316	TRANSCRIPTIONal
BF28_RS13390	COG1301	dicarboxylic acid transport
BF28_RS13395	COG4166	transmembrane transport
BF28_RS13400	COG4166	transmembrane transport
BF28_RS13405	COG4166	transmembrane transport
BF28_RS13410	COG2226	methyltransferase
BF28_RS13455	COG0697	spore germination
BF28_RS13465	COG3383	formate dehydrogenase (NAD+) activity
BF28_RS13470	COG2427	Protein of unknown function (DUF1641)
BF28_RS13475	COG5609	conserved protein (DUF2294)
BF28_RS13480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF28_RS13490	COG2116	formate transmembrane transporter activity
BF28_RS13495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_RS13500	COG0303	'Molybdopterin
BF28_RS13505	COG0314	molybdopterin synthase activity
BF28_RS13515	COG0489	protein tyrosine kinase activity
BF28_RS13530	COG3326	Membrane
BF28_RS13535	COG2962	Rard protein
BF28_RS13540	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BF28_RS13545	COG1657	PFAM Prenyltransferase squalene oxidase
BF28_RS13555	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS13560	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS13570	COG4145	pantothenate transmembrane transporter activity
BF28_RS13585	COG0165	Argininosuccinate lyase
BF28_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS13625	COG0716	FMN binding
BF28_RS13665	COG2720	vancomycin resistance protein
BF28_RS13670	COG2514	catechol 2,3-dioxygenase activity
BF28_RS13685	COG1285	pathogenesis
BF28_RS13695	COG1024	Enoyl-CoA hydratase
BF28_RS13700	COG1216	Glycosyl transferase, family 2
BF28_RS13735	COG0277	FAD linked oxidase domain protein
BF28_RS13740	COG0385	Bile acid
BF28_RS13755	COG2808	Putative FMN-binding domain
BF28_RS13765	COG0457	Tetratricopeptide repeat
BF28_RS13775	COG0604	alcohol dehydrogenase
BF28_RS13780	COG0640	Transcriptional regulator
BF28_RS13805	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_RS13840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_RS13845	COG1164	Oligoendopeptidase f
BF28_RS13850	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BF28_RS13855	COG1193	negative regulation of DNA recombination
BF28_RS13885	COG0583	DNA-binding transcription factor activity
BF28_RS13920	COG0384	phenazine biosynthesis protein PhzF
BF28_RS13925	COG3739	integral membrane protein
BF28_RS13930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS13935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS13940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS13955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_RS13960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF28_RS13995	COG2814	Major facilitator Superfamily
BF28_RS14000	COG1113	amino acid transport
BF28_RS14005	COG0604	alcohol dehydrogenase
BF28_RS14025	COG0714	Associated with various cellular activities
BF28_RS14065	COG2072	flavoprotein involved in K transport
BF28_RS14075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_RS14115	COG1151	hydroxylamine reductase activity
BF28_RS14140	COG3152	Membrane
BF28_RS14180	COG1309	transcriptional regulator
BF28_RS14195	COG1191	sigma factor activity
BF28_RS14225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF28_RS14230	COG1733	regulation of RNA biosynthetic process
BF28_RS14235	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_RS14240	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS14260	COG0384	phenazine biosynthesis protein PhzF
BF28_RS14280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS14300	COG1733	regulation of RNA biosynthetic process
BF28_RS14305	COG1733	regulation of RNA biosynthetic process
BF28_RS14310	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF28_RS14315	COG0673	inositol 2-dehydrogenase activity
BF28_RS14320	COG2188	Transcriptional regulator
BF28_RS14325	COG1733	regulation of RNA biosynthetic process
BF28_RS14335	COG1393	Belongs to the ArsC family
BF28_RS14360	COG0814	amino acid
BF28_RS14365	COG0346	lactoylglutathione lyase activity
BF28_RS14380	COG2814	Major facilitator Superfamily
BF28_RS14385	COG0656	L-ascorbic acid biosynthetic process
BF28_RS14400	COG1733	regulation of RNA biosynthetic process
BF28_RS14405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF28_RS14405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF28_RS14410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_RS14410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF28_RS14425	COG0840	transmembrane signaling receptor activity
BF28_RS14440	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS14460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF28_RS14465	COG0604	alcohol dehydrogenase
BF28_RS14470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF28_RS14475	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF28_RS14485	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BF28_RS14490	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF28_RS14500	COG1070	Carbohydrate kinase
BF28_RS14505	COG2706	6-phosphogluconolactonase activity
BF28_RS14510	COG3813	Protein conserved in bacteria
BF28_RS14515	COG1357	PFAM Pentapeptide repeats (8 copies)
BF28_RS14520	COG0697	spore germination
BF28_RS14550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF28_RS14560	COG0789	Transcriptional regulator
BF28_RS14565	COG1253	flavin adenine dinucleotide binding
BF28_RS14595	COG0477	Major facilitator Superfamily
BF28_RS14605	COG2226	methyltransferase
BF28_RS14625	COG0628	permease
BF28_RS14640	COG1136	(ABC) transporter
BF28_RS14640	COG0577	efflux transmembrane transporter activity
BF28_RS14650	COG0110	maltose O-acetyltransferase activity
BF28_RS14660	COG1940	carbohydrate kinase activity
BF28_RS14665	COG0346	lactoylglutathione lyase activity
BF28_RS14695	COG2365	Tyrosine phosphatase family
BF28_RS14705	COG1011	Hydrolase
BF28_RS14730	COG1131	(ABC) transporter
BF28_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS14760	COG0778	Nitroreductase
BF28_RS14765	COG1733	regulation of RNA biosynthetic process
BF28_RS14785	COG2197	response regulator
BF28_RS14795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF28_RS14805	COG3620	sequence-specific DNA binding
BF28_RS14820	COG0789	Transcriptional regulator
BF28_RS14845	COG1288	antiporter activity
BF28_RS14865	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BF28_RS14900	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_RS14910	COG2031	fatty acid transporter
BF28_RS14930	COG2814	Major facilitator Superfamily
BF28_RS14935	COG1846	Transcriptional regulator
BF28_RS14945	COG0477	Major facilitator Superfamily
BF28_RS14985	COG2814	Major facilitator Superfamily
BF28_RS15000	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF28_RS15000	COG3409	Peptidoglycan-binding domain 1 protein
BF28_RS15030	COG2207	Transcriptional regulator
BF28_RS15030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS15040	COG0662	Cupin 2, conserved barrel domain protein
BF28_RS15055	COG1595	DNA-templated transcription, initiation
BF28_RS15075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF28_RS15090	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_RS15115	COG0583	DNA-binding transcription factor activity
BF28_RS15125	COG1139	Iron-sulfur cluster binding protein
BF28_RS15130	COG1556	Lactate utilization protein
BF28_RS15135	COG2271	Major facilitator Superfamily
BF28_RS15140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS15145	COG2808	Putative FMN-binding domain
BF28_RS15150	COG0456	acetyltransferase
BF28_RS15155	COG1846	Transcriptional regulator
BF28_RS15160	COG2364	Membrane
BF28_RS15170	COG5002	protein histidine kinase activity
BF28_RS15170	COG3850	Histidine kinase
BF28_RS15190	COG0577	efflux transmembrane transporter activity
BF28_RS15210	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BF28_RS15215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_RS15225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF28_RS15230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS15245	COG1476	TRANSCRIPTIONal
BF28_RS15265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BF28_RS15315	COG2814	Major facilitator Superfamily
BF28_RS15355	COG2169	Transcriptional regulator
BF28_RS15375	COG0346	lactoylglutathione lyase activity
BF28_RS15395	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS15405	COG0443	Heat shock 70 kDa protein
BF28_RS15420	COG0640	Transcriptional regulator
BF28_RS15425	COG0346	lactoylglutathione lyase activity
BF28_RS15430	COG0798	PFAM Bile acid sodium symporter
BF28_RS15460	COG0577	efflux transmembrane transporter activity
BF28_RS15465	COG1136	(ABC) transporter
BF28_RS15470	COG4641	Protein conserved in bacteria
BF28_RS15475	COG2267	carboxylic ester hydrolase activity
BF28_RS15500	COG1575	Belongs to the MenA family. Type 1 subfamily
BF28_RS15510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS15525	COG1329	Transcriptional regulator
BF28_RS15555	COG5609	conserved protein (DUF2294)
BF28_RS15560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF28_RS15570	COG0288	reversible hydration of carbon dioxide
BF28_RS15600	COG0598	Magnesium transport protein CorA
BF28_RS15605	COG0753	catalase activity
BF28_RS15610	COG0737	Belongs to the 5'-nucleotidase family
BF28_RS15620	COG0531	amino acid
BF28_RS15625	COG0534	Mate efflux family protein
BF28_RS15630	COG0723	plastoquinol--plastocyanin reductase activity
BF28_RS15630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_RS15650	COG1115	amino acid carrier protein
BF28_RS15655	COG2066	Belongs to the glutaminase family
BF28_RS15660	COG4191	Histidine kinase
BF28_RS15665	COG0784	Response regulator, receiver
BF28_RS15670	COG0697	spore germination
BF28_RS15675	COG0531	amino acid
BF28_RS15685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_RS15690	COG0531	amino acid
BF28_RS15695	COG0322	excinuclease ABC activity
BF28_RS15700	COG2801	Transposase and inactivated derivatives
BF28_RS15705	COG1396	sequence-specific DNA binding
BF28_RS15710	COG0252	asparaginase activity
BF28_RS15715	COG1027	Aspartate ammonia-lyase
BF28_RS15725	COG1136	(ABC) transporter
BF28_RS15740	COG0789	Transcriptional regulator
BF28_RS15750	COG1063	alcohol dehydrogenase
BF28_RS15780	COG1113	amino acid transport
BF28_RS15785	COG1280	lysine exporter protein (LysE YggA)
BF28_RS15790	COG3403	YqcI/YcgG family
BF28_RS15795	COG5577	PFAM Coat F domain
BF28_RS15810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS15820	COG3848	Pyruvate phosphate dikinase
BF28_RS15820	COG0574	Belongs to the PEP-utilizing enzyme family
BF28_RS15840	COG3314	Sporulation integral membrane protein YlbJ
BF28_RS15855	COG1960	acyl-CoA dehydrogenase activity
BF28_RS15865	COG0640	Transcriptional regulator
BF28_RS15870	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_RS15890	COG1414	Transcriptional regulator
BF28_RS15895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BF28_RS15900	COG1984	allophanate hydrolase subunit 2
BF28_RS15935	COG0768	penicillin binding
BF28_RS15965	COG4335	DNA alkylation repair
BF28_RS15975	COG0833	amino acid
BF28_RS15985	COG0730	response to heat
BF28_RS16015	COG0596	Alpha beta hydrolase
BF28_RS16020	COG0745	RESPONSE REGULATOR receiver
BF28_RS16025	COG0642	Histidine kinase
BF28_RS16040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS16060	COG0456	acetyltransferase
BF28_RS16065	COG2207	Transcriptional regulator
BF28_RS16090	COG1136	(ABC) transporter
BF28_RS16100	COG1725	Transcriptional regulator
BF28_RS16135	COG1846	Transcriptional regulator
BF28_RS16140	COG0778	Nitroreductase
BF28_RS16150	COG0714	Associated with various cellular activities
BF28_RS16175	COG1280	lysine exporter protein (LysE YggA)
BF28_RS16185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BF28_RS16190	COG1846	Transcriptional regulator
BF28_RS16205	COG1116	anion transmembrane transporter activity
BF28_RS16210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_RS16215	COG0753	catalase activity
BF28_RS16220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF28_RS16230	COG0463	Glycosyl transferase, family 2
BF28_RS16255	COG0463	Glycosyl transferase, family 2
BF28_RS16280	COG0714	Associated with various cellular activities
BF28_RS16305	COG0346	lactoylglutathione lyase activity
BF28_RS16330	COG3279	Response regulator of the LytR AlgR family
BF28_RS16340	COG4377	Putative membrane peptidase family (DUF2324)
BF28_RS16355	COG3655	Transcriptional regulator
BF28_RS16365	COG1785	Belongs to the alkaline phosphatase family
BF28_RS16370	COG3239	Fatty acid desaturase
BF28_RS16375	COG1690	Belongs to the RtcB family
BF28_RS16380	COG0833	amino acid
BF28_RS16385	COG1414	Transcriptional regulator
BF28_RS16390	COG4187	Peptidase family M20/M25/M40
BF28_RS16395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_RS16410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS16430	COG2329	Antibiotic biosynthesis monooxygenase
BF28_RS16465	COG1070	Carbohydrate kinase
BF28_RS16470	COG2390	Transcriptional regulator
BF28_RS16480	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF28_RS16490	COG1879	ABC-type sugar transport system periplasmic component
BF28_RS16515	COG1024	Enoyl-CoA hydratase
BF28_RS16520	COG2610	gluconate transmembrane transporter activity
BF28_RS16530	COG1388	LysM domain
BF28_RS16530	COG3584	3D domain protein
BF28_RS16565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF28_RS16565	COG1605	Chorismate mutase
BF28_RS16580	COG0287	Prephenate dehydrogenase
BF28_RS16595	COG1309	transcriptional regulator
BF28_RS16600	COG2409	Drug exporters of the RND superfamily
BF28_RS16600	COG1033	growth of symbiont in host cell
BF28_RS16615	COG0488	(ABC) transporter
BF28_RS16620	COG1368	sulfuric ester hydrolase activity
BF28_RS16625	COG0861	Integral membrane protein TerC family
BF28_RS16630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_RS16670	COG2318	DinB family
BF28_RS16675	COG0697	spore germination
BF28_RS16695	COG2746	aminoglycoside 3-N-acetyltransferase activity
BF28_RS16740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF28_RS16745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_RS16750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF28_RS16765	COG0628	permease
BF28_RS16815	COG1131	(ABC) transporter
BF28_RS16840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF28_RS16845	COG0436	Aminotransferase
BF28_RS16880	COG2226	methyltransferase
BF28_RS16895	COG2261	transglycosylase associated protein
BF28_RS16915	COG2814	Major facilitator Superfamily
BF28_RS16915	COG0477	Major facilitator Superfamily
BF28_RS16920	COG4533	DNA binding
BF28_RS16925	COG0789	Transcriptional regulator
BF28_RS16930	COG1664	Polymer-forming cytoskeletal
BF28_RS16940	COG2814	Major facilitator Superfamily
BF28_RS16975	COG1307	EDD domain protein, DegV family
BF28_RS16990	COG1164	Oligoendopeptidase f
BF28_RS17030	COG0745	RESPONSE REGULATOR receiver
BF28_RS17035	COG5002	protein histidine kinase activity
BF28_RS17040	COG2936	dipeptidyl-peptidase activity
BF28_RS17085	COG4948	Mandelate Racemase Muconate Lactonizing
BF28_RS17095	COG4166	transmembrane transport
BF28_RS17100	COG0519	Catalyzes the synthesis of GMP from XMP
BF28_RS17105	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF28_RS17120	COG0586	Pfam SNARE associated Golgi protein
BF28_RS17125	COG1078	dGTPase activity
BF28_RS17175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_RS17180	COG3938	Belongs to the proline racemase family
BF28_RS17190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF28_RS17195	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS17200	COG1115	amino acid carrier protein
BF28_RS17205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BF28_RS17215	COG3397	chitin binding
BF28_RS17235	COG4637	Psort location Cytoplasmic, score
BF28_RS17265	COG0514	ATP-dependent DNA helicase (RecQ)
BF28_RS17270	COG2105	PFAM AIG2 family protein
BF28_RS17285	COG3973	AAA domain
BF28_RS17330	COG0658	competence protein
BF28_RS17330	COG2333	competence protein COMEC
BF28_RS17340	COG2315	Protein conserved in bacteria
BF28_RS17345	COG2226	methyltransferase
BF28_RS17350	COG2205	protein histidine kinase activity
BF28_RS17365	COG3397	chitin binding
BF28_RS17370	COG2153	protein acetylation
BF28_RS17400	COG0517	IMP dehydrogenase activity
BF28_RS17400	COG4175	Glycine betaine
BF28_RS17405	COG4176	ABC-type proline glycine betaine transport system permease component
BF28_RS17430	COG0494	nUDIX hydrolase
BF28_RS17440	COG0572	uridine kinase
BF28_RS17445	COG0456	acetyltransferase
BF28_RS17445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BF28_RS17450	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS17460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BF28_RS17465	COG0022	dehydrogenase e1 component
BF28_RS17470	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF28_RS17475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF28_RS17495	COG1349	DNA-binding transcription factor activity
BF28_RS17515	COG3284	Transcriptional regulator
BF28_RS17545	COG1309	transcriptional regulator
BF28_RS17580	COG2959	enzyme of heme biosynthesis
BF28_RS17595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS17630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS17635	COG0697	spore germination
BF28_RS17645	COG0201	protein transport
BF28_RS17650	COG0346	lactoylglutathione lyase activity
BF28_RS17670	COG3227	Zinc metalloprotease (Elastase)
BF28_RS17675	COG1523	belongs to the glycosyl hydrolase 13 family
BF28_RS17700	COG1011	Hydrolase
BF28_RS17720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_RS17760	COG0322	excinuclease ABC activity
BF28_RS17775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF28_RS17800	COG4667	esterase of the alpha-beta hydrolase superfamily
BF28_RS17825	COG3878	Protein conserved in bacteria
BF28_RS17845	COG1051	belongs to the nudix hydrolase family
BF28_RS17850	COG0592	DNA-directed DNA polymerase activity
BF28_RS17855	COG2816	NAD+ diphosphatase activity
BF28_RS17860	COG2223	nitrite transmembrane transporter activity
BF28_RS17900	COG0697	spore germination
BF28_RS17905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS17925	COG0584	glycerophosphoryl diester phosphodiesterase
BF28_RS17940	COG2814	Major facilitator Superfamily
BF28_RS17955	COG2816	NAD+ diphosphatase activity
BF28_RS18000	COG0693	protein deglycase activity
BF28_RS18050	COG0768	penicillin binding
BF28_RS18055	COG0671	phosphoesterase, PA-phosphatase related
BF28_RS18060	COG0604	alcohol dehydrogenase
BF28_RS18075	COG2205	protein histidine kinase activity
BF28_RS18095	COG1794	racemase activity, acting on amino acids and derivatives
BF28_RS18100	COG1819	glycosyl
BF28_RS18105	COG0768	penicillin binding
BF28_RS18110	COG5002	protein histidine kinase activity
BF28_RS18115	COG0561	phosphatase activity
BF28_RS18150	COG2124	cytochrome p450
BF28_RS18245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF28_RS18255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS18260	COG0460	homoserine dehydrogenase
BF28_RS18280	COG0577	efflux transmembrane transporter activity
BF28_RS18285	COG1136	(ABC) transporter
BF28_RS18300	COG0488	(ABC) transporter
BF28_RS18310	COG2205	protein histidine kinase activity
BF28_RS18315	COG0745	RESPONSE REGULATOR receiver
BF28_RS18325	COG3773	Cell wall hydrolase
BF28_RS18330	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BF28_RS18340	COG3386	PFAM SMP-30 Gluconolaconase
BF28_RS18350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF28_RS18375	COG2323	membrane
BF28_RS18380	COG1063	alcohol dehydrogenase
BF28_RS18395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS18435	COG2226	methyltransferase
BF28_RS18445	COG2814	Major facilitator Superfamily
BF28_RS18485	COG3227	Zinc metalloprotease (Elastase)
BF28_RS18510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF28_RS18535	COG1686	Belongs to the peptidase S11 family
BF28_RS18540	COG2318	DinB family
BF28_RS18550	COG0572	uridine kinase
BF28_RS18555	COG1247	-acetyltransferase
BF28_RS18575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF28_RS18580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF28_RS18585	COG1024	Enoyl-CoA hydratase
BF28_RS18590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF28_RS18595	COG0511	ligase activity, forming carbon-carbon bonds
BF28_RS18600	COG0439	Biotin carboxylase
BF28_RS18605	COG1960	acyl-CoA dehydrogenase activity
BF28_RS18620	COG1309	transcriptional regulator
BF28_RS18630	COG1131	(ABC) transporter
BF28_RS18645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_RS18680	COG0488	(ABC) transporter
BF28_RS18685	COG1309	transcriptional regulator
BF28_RS18705	COG1876	peptidase activity
BF28_RS18720	COG1476	TRANSCRIPTIONal
BF28_RS18725	COG0457	Tetratricopeptide repeat
BF28_RS18735	COG0737	Belongs to the 5'-nucleotidase family
BF28_RS18750	COG3718	enzyme involved in inositol metabolism
BF28_RS18780	COG0673	inositol 2-dehydrogenase activity
BF28_RS18785	COG2814	Major facilitator Superfamily
BF28_RS18790	COG1609	Transcriptional regulator
BF28_RS18795	COG0671	phosphoesterase, PA-phosphatase related
BF28_RS18800	COG2367	Beta-lactamase
BF28_RS18805	COG0768	penicillin binding
BF28_RS18810	COG0768	penicillin binding
BF28_RS18820	COG1595	DNA-templated transcription, initiation
BF28_RS18835	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF28_RS18875	COG1846	Transcriptional regulator
BF28_RS18880	COG3961	Belongs to the TPP enzyme family
BF28_RS18890	COG3615	Tellurite resistance protein tehB
BF28_RS18890	COG0500	methyltransferase
BF28_RS18895	COG0577	efflux transmembrane transporter activity
BF28_RS18895	COG1136	(ABC) transporter
BF28_RS18910	COG1309	transcriptional regulator
BF28_RS18935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS18955	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF28_RS18965	COG2971	BadF BadG BcrA BcrD
BF28_RS18990	COG1649	PFAM Uncharacterised BCR, COG1649
BF28_RS19015	COG1595	DNA-templated transcription, initiation
BF28_RS19030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF28_RS19060	COG1396	sequence-specific DNA binding
BF28_RS19080	COG1132	(ABC) transporter
BF28_RS19085	COG1132	(ABC) transporter
BF28_RS19100	COG2258	MOSC domain
BF28_RS19105	COG0583	DNA-binding transcription factor activity
BF28_RS19120	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF28_RS19125	COG0583	DNA-binding transcription factor activity
BF28_RS19130	COG2814	Major facilitator Superfamily
BF28_RS19135	COG1846	Transcriptional regulator
BF28_RS19145	COG0010	Belongs to the arginase family
BF28_RS19160	COG1278	Cold shock
BF28_RS19170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS19185	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF28_RS19210	COG1247	-acetyltransferase
BF28_RS19245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS19280	COG2226	methyltransferase
BF28_RS19290	COG0028	Belongs to the TPP enzyme family
BF28_RS19305	COG2814	Major facilitator Superfamily
BF28_RS19310	COG0596	Alpha beta hydrolase
BF28_RS19320	COG1136	(ABC) transporter
BF28_RS19325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF28_RS19330	COG1187	pseudouridine synthase activity
BF28_RS19335	COG2329	Antibiotic biosynthesis monooxygenase
BF28_RS19350	COG1115	amino acid carrier protein
BF28_RS19360	COG2318	DinB family
BF28_RS19370	COG0776	regulation of translation
BF28_RS19385	COG2814	Major facilitator Superfamily
BF28_RS19395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BF28_RS19400	COG3433	isochorismatase activity
BF28_RS19400	COG1535	isochorismatase
BF28_RS19405	COG1021	2,3-dihydroxybenzoate-AMP ligase
BF28_RS19410	COG1169	isochorismate synthase
BF28_RS19415	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS19420	COG2223	nitrite transmembrane transporter activity
BF28_RS19450	COG0419	ATPase involved in DNA repair
BF28_RS19455	COG0420	3'-5' exonuclease activity
BF28_RS19470	COG1024	Enoyl-CoA hydratase
BF28_RS19475	COG1280	lysine exporter protein (LysE YggA)
BF28_RS19485	COG2084	Dehydrogenase
BF28_RS19490	COG1960	acyl-CoA dehydrogenase activity
BF28_RS19495	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BF28_RS19500	COG2079	MmgE PrpD family protein
BF28_RS19505	COG0372	Belongs to the citrate synthase family
BF28_RS19510	COG4841	protein insertion into membrane
BF28_RS19515	COG2814	Major facilitator Superfamily
BF28_RS19525	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF28_RS19525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_RS19565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF28_RS19635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_RS19640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF28_RS19645	COG0671	phosphoesterase, PA-phosphatase related
BF28_RS19650	COG4326	sporulation control protein
BF28_RS19655	COG0515	serine threonine protein kinase
BF28_RS19655	COG4991	sh3 domain protein
BF28_RS19655	COG3064	Membrane
BF28_RS19690	COG1509	lysine 2,3-aminomutase activity
BF28_RS19695	COG3829	transcription factor binding
BF28_RS19700	COG0456	acetyltransferase
BF28_RS19705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF28_RS19710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BF28_RS19715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BF28_RS19720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF28_RS19735	COG5506	Protein of unknown function (DUF1694)
BF28_RS19740	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS19745	COG1253	flavin adenine dinucleotide binding
BF28_RS19780	COG1174	glycine betaine transport
BF28_RS19785	COG0517	IMP dehydrogenase activity
BF28_RS19785	COG1125	glycine betaine transport
BF28_RS19840	COG1064	alcohol dehydrogenase
BF28_RS19845	COG1737	Transcriptional regulator
BF28_RS19850	COG2197	response regulator
BF28_RS19855	COG2203	Gaf domain
BF28_RS19855	COG4585	Histidine kinase
BF28_RS19860	COG0668	transmembrane transport
BF28_RS19870	COG1051	belongs to the nudix hydrolase family
BF28_RS19875	COG1335	isochorismatase
BF28_RS19895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_RS19900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS19920	COG0367	asparagine synthase
BF28_RS19925	COG0071	Belongs to the small heat shock protein (HSP20) family
BF28_RS19930	COG1999	signal sequence binding
BF28_RS19935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BF28_RS19940	COG1307	EDD domain protein, DegV family
BF28_RS19950	COG0805	protein transport
BF28_RS19960	COG1272	protein, Hemolysin III
BF28_RS19965	COG0204	Acyl-transferase
BF28_RS19975	COG0768	penicillin binding
BF28_RS19990	COG3250	beta-galactosidase activity
BF28_RS19995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_RS20015	COG0546	phosphoglycolate phosphatase activity
BF28_RS20025	COG4473	ABC transporter
BF28_RS20030	COG1131	(ABC) transporter
BF28_RS20040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF28_RS20045	COG0456	acetyltransferase
BF28_RS20055	COG1794	racemase activity, acting on amino acids and derivatives
BF28_RS20060	COG1454	alcohol dehydrogenase
BF28_RS20065	COG2610	gluconate transmembrane transporter activity
BF28_RS20090	COG0733	neurotransmitter:sodium symporter activity
BF28_RS20165	COG1674	ftsk spoiiie
BF28_RS20185	COG0017	Asparaginyl-tRNA synthetase
BF28_RS20190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF28_RS20225	COG2521	methyltransferase
BF28_RS20225	COG2136	Putative SAM-dependent methyltransferase
BF28_RS20240	COG1413	lyase activity
BF28_RS20255	COG0629	single-stranded DNA binding
BF28_RS20270	COG0488	(ABC) transporter
BF28_RS20275	COG1418	mRNA catabolic process
BF28_RS20310	COG2359	stage V sporulation protein S
BF28_RS20345	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF28_RS20350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF28_RS20355	COG2146	nitrite reductase [NAD(P)H] activity
BF28_RS20360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BF28_RS20360	COG1587	Uroporphyrinogen-III synthase
BF28_RS20370	COG1648	precorrin-2 dehydrogenase activity
BF28_RS20385	COG2223	nitrite transmembrane transporter activity
BF28_RS20395	COG0314	molybdopterin synthase activity
BF28_RS20400	COG0303	'Molybdopterin
BF28_RS20405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_RS20410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF28_RS20415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF28_RS20420	COG2181	nitrate reductase activity
BF28_RS20425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BF28_RS20430	COG1140	nitrate reductase beta subunit
BF28_RS20435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BF28_RS20450	COG0714	Associated with various cellular activities
BF28_RS20455	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BF28_RS20460	COG1305	Transglutaminase-like
BF28_RS20465	COG0386	Belongs to the glutathione peroxidase family
BF28_RS20475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BF28_RS20475	COG0426	domain, Protein
BF28_RS20490	COG1595	DNA-templated transcription, initiation
BF28_RS20495	COG0604	alcohol dehydrogenase
BF28_RS20505	COG0346	lactoylglutathione lyase activity
BF28_RS20510	COG1082	Xylose isomerase domain protein TIM barrel
BF28_RS20530	COG2226	methyltransferase
BF28_RS20555	COG3874	Sporulation protein YtfJ
BF28_RS20620	COG0456	acetyltransferase
BF28_RS20650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS20655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS20660	COG1819	glycosyl
BF28_RS20680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF28_RS20690	COG0561	phosphatase activity
BF28_RS20710	COG2211	Major facilitator Superfamily
BF28_RS20715	COG0154	amidase activity
BF28_RS20725	COG1876	peptidase activity
BF28_RS20735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_RS20755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF28_RS20760	COG1114	Component of the transport system for branched-chain amino acids
BF28_RS20775	COG1253	flavin adenine dinucleotide binding
BF28_RS20780	COG2839	Protein conserved in bacteria
BF28_RS20785	COG0702	epimerase
BF28_RS20800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS20805	COG1607	acyl-coa hydrolase
BF28_RS20810	COG3689	TIGRFAM TIGR03943 family protein
BF28_RS20815	COG0701	Predicted permease
BF28_RS20825	COG2244	polysaccharide biosynthetic process
BF28_RS20830	COG0586	Pfam SNARE associated Golgi protein
BF28_RS20835	COG1051	belongs to the nudix hydrolase family
BF28_RS20840	COG5337	Spore coat protein CotH
BF28_RS20850	COG0406	alpha-ribazole phosphatase activity
BF28_RS20865	COG4166	transmembrane transport
BF28_RS20875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BF28_RS20885	COG0702	epimerase
BF28_RS20895	COG3443	Belongs to the bacterial solute-binding protein 9 family
BF28_RS20895	COG0803	Belongs to the bacterial solute-binding protein 9 family
BF28_RS20955	COG0456	acetyltransferase
BF28_RS20960	COG0523	cobalamin synthesis protein
BF28_RS20965	COG4989	oxidoreductase activity
BF28_RS20975	COG1231	oxidoreductase activity
BF28_RS20985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BF28_RS21000	COG0783	Belongs to the Dps family
BF28_RS21005	COG3949	Membrane
BF28_RS21025	COG0840	transmembrane signaling receptor activity
BF28_RS21050	COG2814	Major facilitator Superfamily
BF28_RS21055	COG0667	Aldo Keto reductase
BF28_RS21060	COG0640	Transcriptional regulator
BF28_RS21065	COG1404	Belongs to the peptidase S8 family
BF28_RS21070	COG2002	toxin-antitoxin pair type II binding
BF28_RS21075	COG0577	efflux transmembrane transporter activity
BF28_RS21110	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF28_RS21120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS21125	COG1279	arginine transmembrane transporter activity
BF28_RS21130	COG2814	Major facilitator Superfamily
BF28_RS21140	COG1082	Xylose isomerase domain protein TIM barrel
BF28_RS21150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF28_RS21170	COG1247	-acetyltransferase
BF28_RS21175	COG1285	pathogenesis
BF28_RS21190	COG5002	protein histidine kinase activity
BF28_RS21195	COG0745	RESPONSE REGULATOR receiver
BF28_RS21205	COG1316	TRANSCRIPTIONal
BF28_RS21230	COG0460	homoserine dehydrogenase
BF28_RS21260	COG4122	O-methyltransferase activity
BF28_RS21265	COG0300	oxidoreductase activity
BF28_RS21275	COG5002	protein histidine kinase activity
BF28_RS21280	COG0745	RESPONSE REGULATOR receiver
BF28_RS21285	COG1132	(ABC) transporter
BF28_RS21295	COG0791	NLP P60 protein
BF28_RS21295	COG1388	LysM domain
BF28_RS21310	COG1686	Belongs to the peptidase S11 family
BF28_RS21315	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_RS21330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BF28_RS21335	COG4988	ABC transporter
BF28_RS21340	COG1294	oxidase, subunit
BF28_RS21345	COG1271	oxidase subunit
BF28_RS21370	COG1942	4-Oxalocrotonate Tautomerase
BF28_RS21380	COG0583	DNA-binding transcription factor activity
BF28_RS21400	COG0411	ABC transporter
BF28_RS21410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_RS21415	COG2030	dehydratase
BF28_RS21420	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS21435	COG0523	cobalamin synthesis protein
BF28_RS21440	COG1231	oxidoreductase activity
BF28_RS21450	COG0628	permease
BF28_RS21465	COG0778	Nitroreductase
BF28_RS21470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF28_RS21475	COG1959	2 iron, 2 sulfur cluster binding
BF28_RS21480	COG0583	DNA-binding transcription factor activity
BF28_RS21485	COG0697	spore germination
BF28_RS21495	COG4549	nuclear export factor GLE1
BF28_RS21500	COG2372	response to copper ion
BF28_RS21500	COG1276	copper resistance
BF28_RS21510	COG1114	Component of the transport system for branched-chain amino acids
BF28_RS21530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF28_RS21535	COG2002	toxin-antitoxin pair type II binding
BF28_RS21550	COG1131	(ABC) transporter
BF28_RS21565	COG1132	(ABC) transporter
BF28_RS21595	COG0006	proline dipeptidase activity
BF28_RS21620	COG4846	Membrane protein involved in cytochrome C biogenesis
BF28_RS21630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BF28_RS21635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS21645	COG2390	Transcriptional regulator
BF28_RS21670	COG0531	amino acid
BF28_RS21680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF28_RS21695	COG1914	H( )-stimulated, divalent metal cation uptake system
BF28_RS21720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS21745	COG4166	transmembrane transport
BF28_RS21750	COG1073	alpha beta
BF28_RS21770	COG0427	acetyl-CoA hydrolase
BF28_RS21775	COG3279	Response regulator of the LytR AlgR family
BF28_RS21785	COG3384	dioxygenase
BF28_RS21790	COG2814	Major facilitator Superfamily
BF28_RS21815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BF28_RS21835	COG0028	Belongs to the TPP enzyme family
BF28_RS21840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_RS21850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF28_RS21865	COG2323	membrane
BF28_RS21870	COG5566	PFAM Mor transcription activator
BF28_RS21880	COG0733	neurotransmitter:sodium symporter activity
BF28_RS21885	COG2244	polysaccharide biosynthetic process
BF28_RS21900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF28_RS21905	COG2223	nitrite transmembrane transporter activity
BF28_RS21910	COG4166	transmembrane transport
BF28_RS21915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF28_RS21925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_RS21930	COG0477	Major facilitator Superfamily
BF28_RS21940	COG1695	Transcriptional regulator
BF28_RS21955	COG1105	Belongs to the carbohydrate kinase PfkB family
BF28_RS21970	COG2222	sugar isomerase
BF28_RS21975	COG2188	Transcriptional regulator
BF28_RS21985	COG0395	ABC-type sugar transport system, permease component
BF28_RS21990	COG1175	transmembrane transport
BF28_RS22000	COG2508	Transcriptional regulator
BF28_RS22005	COG3842	ATPase activity
BF28_RS22020	COG2814	Major facilitator Superfamily
BF28_RS22030	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_RS22035	COG1051	belongs to the nudix hydrolase family
BF28_RS22070	COG3620	sequence-specific DNA binding
BF28_RS22095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF28_RS22100	COG0784	Response regulator, receiver
BF28_RS22105	COG4191	Histidine kinase
BF28_RS22110	COG0281	malic enzyme
BF28_RS22115	COG1027	Aspartate ammonia-lyase
BF28_RS22125	COG0528	UMP kinase activity
BF28_RS22130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS22145	COG1131	(ABC) transporter
BF28_RS22180	COG2733	membrane
BF28_RS22205	COG0785	Cytochrome C biogenesis protein
BF28_RS22225	COG3340	Belongs to the peptidase S51 family
BF28_RS22230	COG0534	Mate efflux family protein
BF28_RS22250	COG0114	fumarate hydratase activity
BF28_RS22255	COG1757	Na H antiporter
BF28_RS22260	COG0438	transferase activity, transferring glycosyl groups
BF28_RS22260	COG1216	Glycosyl transferase, family 2
BF28_RS22265	COG0523	cobalamin synthesis protein
BF28_RS22270	COG0697	spore germination
BF28_RS22275	COG1802	Transcriptional regulator
BF28_RS22305	COG0367	asparagine synthase
BF28_RS22315	COG1846	Transcriptional regulator
BF28_RS22335	COG0406	alpha-ribazole phosphatase activity
BF28_RS22345	COG1686	Belongs to the peptidase S11 family
BF28_RS22370	COG1234	tRNA 3'-trailer cleavage
BF28_RS22380	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF28_RS22385	COG3842	ATPase activity
BF28_RS22390	COG0583	DNA-binding transcription factor activity
BF28_RS22415	COG2329	Antibiotic biosynthesis monooxygenase
BF28_RS22435	COG1309	transcriptional regulator
BF28_RS22465	COG4786	Flagellar basal body rod
BF28_RS22470	COG1419	protein localization to endoplasmic reticulum
BF28_RS22475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF28_RS22480	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BF28_RS22490	COG1987	bacterial-type flagellum assembly
BF28_RS22495	COG1338	Plays a role in the flagellum-specific transport system
BF28_RS22505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_RS22505	COG1776	CheC inhibitor of MCP methylation
BF28_RS22510	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_RS22520	COG0741	lytic transglycosylase activity
BF28_RS22525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_RS22525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_RS22530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_RS22540	COG0784	Response regulator, receiver
BF28_RS22540	COG0835	chemotaxis
BF28_RS22575	COG1157	protein secretion by the type III secretion system
BF28_RS22585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_RS22590	COG1766	The M ring may be actively involved in energy transduction
BF28_RS22600	COG1558	bacterial-type flagellum-dependent cell motility
BF28_RS22605	COG1815	bacterial-type flagellum-dependent cell motility
BF28_RS22625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BF28_RS22630	COG1256	bacterial-type flagellum assembly
BF28_RS22650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF28_RS22665	COG1776	CheC inhibitor of MCP methylation
BF28_RS22665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BF28_RS22670	COG2198	Histidine kinase
BF28_RS22670	COG0643	Histidine kinase
BF28_RS22675	COG2201	protein-glutamate methylesterase activity
BF28_RS22680	COG1360	Flagellar Motor Protein
BF28_RS22685	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BF28_RS22695	COG1923	regulation of RNA biosynthetic process
BF28_RS22760	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BF28_RS22765	COG2323	membrane
BF28_RS22775	COG0789	Transcriptional regulator
BF28_RS22775	COG4978	Transcriptional regulator
BF28_RS22780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BF28_RS22785	COG0475	glutathione-regulated potassium exporter activity
BF28_RS22795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF28_RS22800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_RS22805	COG3162	membrane
BF28_RS22820	COG1280	lysine exporter protein (LysE YggA)
BF28_RS22825	COG3403	YqcI/YcgG family
BF28_RS22860	COG0328	RNA-DNA hybrid ribonuclease activity
BF28_RS22880	COG0454	-acetyltransferase
BF28_RS22895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF28_RS22910	COG0754	glutathionylspermidine amidase activity
BF28_RS22935	COG0456	acetyltransferase
BF28_RS22945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF28_RS22950	COG2311	Membrane
BF28_RS22955	COG2233	PERMEase
BF28_RS22965	COG0024	Methionine aminopeptidase
BF28_RS22970	COG3173	Aminoglycoside phosphotransferase
BF28_RS22980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BF28_RS22985	COG1199	ATP-dependent helicase activity
BF28_RS22995	COG0116	Belongs to the methyltransferase superfamily
BF28_RS23045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_RS23045	COG4499	WXG100 protein secretion system (Wss), protein YukC
BF28_RS23055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF28_RS23060	COG3935	DnaD domain protein
BF28_RS23080	COG1199	ATP-dependent helicase activity
BF28_RS23080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BF28_RS23120	COG0438	transferase activity, transferring glycosyl groups
BF28_RS23125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BF28_RS23140	COG1694	Mazg nucleotide pyrophosphohydrolase
BF28_RS23150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS23160	COG2738	Putative neutral zinc metallopeptidase
BF28_RS23175	COG4347	Protein of unknown function (DUF1405)
BF28_RS23185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BF28_RS23205	COG0457	Tetratricopeptide repeat
BF28_RS23230	COG0142	geranyltranstransferase activity
BF28_RS23240	COG0142	geranyltranstransferase activity
BF28_RS23255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BF28_RS23325	COG0252	asparaginase activity
BF28_RS23330	COG0492	ferredoxin-NADP+ reductase activity
BF28_RS23350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF28_RS23355	COG4862	establishment of competence for transformation
BF28_RS23365	COG1408	metallophosphoesterase
BF28_RS23375	COG1266	CAAX protease self-immunity
BF28_RS23380	COG0514	ATP-dependent DNA helicase (RecQ)
BF28_RS23390	COG1141	Ferredoxin
BF28_RS23395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BF28_RS23405	COG4942	peptidase
BF28_RS23410	COG2096	Adenosyltransferase
BF28_RS23415	COG5002	protein histidine kinase activity
BF28_RS23420	COG0745	RESPONSE REGULATOR receiver
BF28_RS23425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF28_RS23430	COG1333	cytochrome c biogenesis protein
BF28_RS23440	COG1187	pseudouridine synthase activity
BF28_RS23445	COG0700	Nucleoside recognition
BF28_RS23450	COG2715	membrane protein required for spore maturation
BF28_RS23455	COG1686	Belongs to the peptidase S11 family
BF28_RS23460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BF28_RS23475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BF28_RS23475	COG0392	lysyltransferase activity
BF28_RS23495	COG5002	protein histidine kinase activity
BF28_RS23500	COG0582	viral genome integration into host DNA
BF28_RS23510	COG1801	Protein of unknown function DUF72
BF28_RS23515	COG3852	Histidine kinase
BF28_RS23530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_RS23535	COG1392	Phosphate transport regulator
BF28_RS23540	COG0306	phosphate transporter
BF28_RS23545	COG0730	response to heat
BF28_RS23590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BF28_RS23600	COG1114	Component of the transport system for branched-chain amino acids
BF28_RS23610	COG2197	response regulator
BF28_RS23615	COG4585	Histidine kinase
BF28_RS23620	COG4758	membrane
BF28_RS23635	COG1757	Na H antiporter
BF28_RS23655	COG0733	neurotransmitter:sodium symporter activity
BF28_RS23665	COG1648	precorrin-2 dehydrogenase activity
BF28_RS23685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BF28_RS23690	COG0529	Catalyzes the synthesis of activated sulfate
BF28_RS23710	COG0019	diaminopimelate decarboxylase activity
BF28_RS23720	COG1368	sulfuric ester hydrolase activity
BF28_RS23725	COG1183	phosphatidylcholine synthase activity
BF28_RS23730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF28_RS23740	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BF28_RS23815	COG0440	acetolactate synthase activity
BF28_RS23820	COG0028	Belongs to the TPP enzyme family
BF28_RS23825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF28_RS23855	COG3874	Sporulation protein YtfJ
BF28_RS23860	COG4709	membrane
BF28_RS23865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF28_RS23870	COG1301	dicarboxylic acid transport
BF28_RS23880	COG1846	Transcriptional regulator
BF28_RS23895	COG1968	undecaprenyl-diphosphatase activity
BF28_RS23920	COG3173	Aminoglycoside phosphotransferase
BF28_RS23935	COG0716	FMN binding
BF28_RS23960	COG1696	Membrane protein involved in D-alanine export
BF28_RS23970	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BF28_RS23975	COG2070	2-Nitropropane dioxygenase
BF28_RS23980	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF28_RS23990	COG1335	isochorismatase
BF28_RS24000	COG1522	sequence-specific DNA binding
BF28_RS24010	COG1266	CAAX protease self-immunity
BF28_RS24015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BF28_RS24020	COG1131	(ABC) transporter
BF28_RS24030	COG1131	(ABC) transporter
BF28_RS24035	COG1725	Transcriptional regulator
BF28_RS24040	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF28_RS24045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF28_RS24050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF28_RS24055	COG1780	Probably involved in ribonucleotide reductase function
BF28_RS24095	COG4873	Protein conserved in bacteria
BF28_RS24110	COG0720	synthase
BF28_RS24120	COG5002	protein histidine kinase activity
BF28_RS24130	COG2318	DinB family
BF28_RS24140	COG1846	Transcriptional regulator
BF28_RS24145	COG3852	Histidine kinase
BF28_RS24155	COG2861	carbohydrate metabolic process
BF28_RS24165	COG0235	Class ii aldolase
BF28_RS24180	COG1349	DNA-binding transcription factor activity
BF28_RS24205	COG3842	ATPase activity
BF28_RS24210	COG1840	ABC-type Fe3 transport system, periplasmic component
BF28_RS24225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF28_RS24235	COG3243	poly(R)-hydroxyalkanoic acid synthase
BF28_RS24240	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS24260	COG2030	dehydratase
BF28_RS24270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF28_RS24275	COG0861	Integral membrane protein TerC family
BF28_RS24280	COG2116	formate transmembrane transporter activity
BF28_RS24290	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BF28_RS24310	COG2186	Transcriptional regulator
BF28_RS24315	COG5002	protein histidine kinase activity
BF28_RS24320	COG0745	RESPONSE REGULATOR receiver
BF28_RS24330	COG3835	regulator
BF28_RS24335	COG0277	FAD linked oxidase domain protein
BF28_RS24340	COG0247	lactate metabolic process
BF28_RS24345	COG2340	Cysteine-rich secretory protein family
BF28_RS24355	COG0564	pseudouridine synthase activity
BF28_RS24365	COG2409	Drug exporters of the RND superfamily
BF28_RS24375	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BF28_RS24380	COG1177	transmembrane transport
BF28_RS24385	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF28_RS24395	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS24430	COG0681	Belongs to the peptidase S26 family
BF28_RS24435	COG1686	Belongs to the peptidase S11 family
BF28_RS24445	COG2226	methyltransferase
BF28_RS24535	COG1476	TRANSCRIPTIONal
BF28_RS24545	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF28_RS24565	COG2226	methyltransferase
BF28_RS24600	COG5634	Uncharacterized conserved protein (DUF2278)
BF28_RS24605	COG1620	l-lactate permease
BF28_RS24640	COG0512	Glutamine amidotransferase of anthranilate synthase
BF28_RS24640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF28_RS24655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_RS24660	COG5492	domain, Protein
BF28_RS24675	COG2382	esterase
BF28_RS24685	COG2153	protein acetylation
BF28_RS24730	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF28_RS24745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF28_RS24765	COG0463	Glycosyl transferase, family 2
BF28_RS24765	COG0457	Tetratricopeptide repeat
BF28_RS24785	COG0463	Glycosyl transferase, family 2
BF28_RS24785	COG1216	Glycosyl transferase, family 2
BF28_RS24790	COG0772	Belongs to the SEDS family
BF28_RS24805	COG0564	pseudouridine synthase activity
BF28_RS24815	COG2357	RelA SpoT domain protein
BF28_RS24825	COG4116	CYTH
BF28_RS24830	COG2346	COG2346, Truncated hemoglobins
BF28_RS24845	COG1164	Oligoendopeptidase f
BF28_RS24855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS24860	COG4862	establishment of competence for transformation
BF28_RS24865	COG0861	Integral membrane protein TerC family
BF28_RS24885	COG4166	transmembrane transport
BF28_RS24890	COG0534	Mate efflux family protein
BF28_RS24895	COG4608	Belongs to the ABC transporter superfamily
BF28_RS24900	COG0444	Belongs to the ABC transporter superfamily
BF28_RS24905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_RS24910	COG0601	transmembrane transport
BF28_RS24915	COG4166	transmembrane transport
BF28_RS24925	COG0180	Tryptophanyl-tRNA synthetase
BF28_RS24935	COG5504	Zn-dependent protease
BF28_RS24940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF28_RS24945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF28_RS24960	COG2267	carboxylic ester hydrolase activity
BF28_RS24970	COG0542	response to heat
BF28_RS24985	COG0561	phosphatase activity
BF28_RS25000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS25010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF28_RS25015	COG2996	Protein conserved in bacteria
BF28_RS25040	COG0004	ammonium transporteR
BF28_RS25045	COG0753	catalase activity
BF28_RS25055	COG0367	asparagine synthase
BF28_RS25080	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF28_RS25140	COG0398	Pfam SNARE associated Golgi protein
BF28_RS25145	COG4903	ComK protein
BF28_RS25160	COG1278	Cold shock
BF28_RS25170	COG2224	Isocitrate lyase
BF28_RS25175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BF28_RS25195	COG0697	spore germination
BF28_RS25200	COG0840	transmembrane signaling receptor activity
BF28_RS25205	COG0501	Belongs to the peptidase M48B family
BF28_RS25230	COG0745	RESPONSE REGULATOR receiver
BF28_RS25235	COG2205	protein histidine kinase activity
BF28_RS25250	COG2207	Transcriptional regulator
BF28_RS25250	COG3708	Transcriptional regulator
BF28_RS25255	COG1595	DNA-templated transcription, initiation
BF28_RS25265	COG1078	dGTPase activity
BF28_RS25270	COG1408	metallophosphoesterase
BF28_RS25290	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS25300	COG0095	Lipoate-protein ligase
BF28_RS25305	COG1234	tRNA 3'-trailer cleavage
BF28_RS25315	COG1609	Transcriptional regulator
BF28_RS25320	COG2378	regulation of single-species biofilm formation
BF28_RS25330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF28_RS25345	COG1511	domain protein
BF28_RS25350	COG1309	transcriptional regulator
BF28_RS25385	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF28_RS25400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF28_RS25405	COG2329	Antibiotic biosynthesis monooxygenase
BF28_RS25410	COG3428	Bacterial PH domain
BF28_RS25415	COG3402	PFAM membrane-flanked domain
BF28_RS25460	COG3428	Bacterial PH domain
BF28_RS25465	COG3402	PFAM membrane-flanked domain
BF28_RS25475	COG1309	transcriptional regulator
BF28_RS25540	COG4473	ABC transporter
BF28_RS25545	COG1131	(ABC) transporter
BF28_RS25550	COG0537	adenosine 5'-monophosphoramidase activity
BF28_RS25555	COG4980	gas vesicle protein
BF28_RS25580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF28_RS25585	COG3973	AAA domain
BF28_RS25595	COG0477	Major facilitator Superfamily
BF28_RS25600	COG0477	Major facilitator Superfamily
BF28_RS25640	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BF28_RS25650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BF28_RS25655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF28_RS25680	COG2267	carboxylic ester hydrolase activity
BF28_RS25690	COG0457	Tetratricopeptide repeat
BF28_RS25695	COG0346	lactoylglutathione lyase activity
BF28_RS25700	COG0346	lactoylglutathione lyase activity
BF28_RS25740	COG4717	serine-type aminopeptidase activity
BF28_RS25745	COG0420	3'-5' exonuclease activity
BF28_RS25795	COG2205	protein histidine kinase activity
BF28_RS25800	COG0745	RESPONSE REGULATOR receiver
BF28_RS25835	COG2205	protein histidine kinase activity
BF28_RS25835	COG0784	Response regulator, receiver
BF28_RS25835	COG5002	protein histidine kinase activity
BF28_RS25840	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BF28_RS25845	COG2208	phosphoserine phosphatase activity
BF28_RS25855	COG1191	sigma factor activity
BF28_RS25880	COG3237	CsbD-like
BF28_RS25935	COG3437	response regulator, receiver
BF28_RS25935	COG2770	Histidine kinase
BF28_RS25975	COG1959	2 iron, 2 sulfur cluster binding
BF28_RS25995	COG2376	Dihydroxyacetone kinase
BF28_RS26025	COG1183	phosphatidylcholine synthase activity
BF28_RS26035	COG2723	6-phospho-beta-galactosidase activity
BF28_RS26040	COG1263	PTS System
BF28_RS26040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_RS26040	COG2190	(PTS) system
BF28_RS26045	COG3711	transcriptional antiterminator
BF28_RS26055	COG1309	transcriptional regulator
BF28_RS26060	COG3320	Male sterility
BF28_RS26060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF28_RS26145	COG0305	Participates in initiation and elongation during chromosome replication
BF28_RS26160	COG4978	Transcriptional regulator
BF28_RS26160	COG0789	Transcriptional regulator
BF28_RS26195	COG1104	cysteine desulfurase activity
BF28_RS26205	COG0419	ATPase involved in DNA repair
BF28_RS26215	COG0433	COG0433 Predicted ATPase
BF28_RS26260	COG0556	nucleotide-excision repair
BF28_RS26280	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF28_RS26290	COG4608	Belongs to the ABC transporter superfamily
BF28_RS26295	COG0444	Belongs to the ABC transporter superfamily
BF28_RS26300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_RS26305	COG0601	transmembrane transport
BF28_RS26335	COG3938	Belongs to the proline racemase family
BF28_RS26355	COG1363	Peptidase, m42
BF28_RS26375	COG1024	Enoyl-CoA hydratase
BF28_RS26390	COG1696	Membrane protein involved in D-alanine export
BF28_RS26405	COG4196	transglutaminase domain protein
BF28_RS26410	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF28_RS26420	COG2244	polysaccharide biosynthetic process
BF28_RS26450	COG0659	secondary active sulfate transmembrane transporter activity
BF28_RS26460	COG0318	PFAM AMP-dependent synthetase and ligase
BF28_RS26465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF28_RS26470	COG5632	N-Acetylmuramoyl-L-alanine amidase
BF28_RS26470	COG3409	Peptidoglycan-binding domain 1 protein
BF28_RS26480	COG0561	phosphatase activity
BF28_RS26490	COG3527	Alpha-acetolactate decarboxylase
BF28_RS26495	COG0028	Belongs to the TPP enzyme family
BF28_RS26535	COG2197	response regulator
BF28_RS26540	COG4585	Histidine kinase
BF28_RS26565	COG0189	ligase activity
BF28_RS26580	COG1126	abc transporter atp-binding protein
BF28_RS26585	COG0765	amino acid transport
BF28_RS26590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_RS26595	COG1132	(ABC) transporter
BF28_RS26600	COG1132	(ABC) transporter
BF28_RS26610	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS26615	COG0531	amino acid
BF28_RS26625	COG0753	catalase activity
BF28_RS26625	COG0693	protein deglycase activity
BF28_RS26630	COG0693	protein deglycase activity
BF28_RS26640	COG2211	Major facilitator Superfamily
BF28_RS26645	COG4533	DNA binding
BF28_RS26650	COG2249	NAD(P)H dehydrogenase (quinone) activity
BF28_RS26660	COG1733	regulation of RNA biosynthetic process
BF28_RS26665	COG1063	alcohol dehydrogenase
BF28_RS26675	COG2124	cytochrome p450
BF28_RS26680	COG1309	transcriptional regulator
BF28_RS26685	COG0657	acetylesterase activity
BF28_RS26690	COG0477	Major facilitator Superfamily
BF28_RS26695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BF28_RS26700	COG1846	Transcriptional regulator
BF28_RS26710	COG2814	Major facilitator Superfamily
BF28_RS26715	COG1309	transcriptional regulator
BF28_RS26720	COG2076	Multidrug Resistance protein
BF28_RS26735	COG1522	sequence-specific DNA binding
BF28_RS26755	COG2259	Doxx family
BF28_RS26780	COG1737	Transcriptional regulator
BF28_RS26790	COG0475	glutathione-regulated potassium exporter activity
BF28_RS26795	COG0531	amino acid
BF28_RS26830	COG0586	Pfam SNARE associated Golgi protein
BF28_RS26865	COG3546	catalase activity
BF28_RS26870	COG1114	Component of the transport system for branched-chain amino acids
BF28_RS26875	COG0577	efflux transmembrane transporter activity
BF28_RS26890	COG5522	Integral membrane protein (intg_mem_TP0381)
BF28_RS26900	COG1136	(ABC) transporter
BF28_RS26905	COG0577	efflux transmembrane transporter activity
BF28_RS26910	COG3584	3D domain protein
BF28_RS26910	COG1388	LysM domain
BF28_RS26930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BF28_RS26935	COG1447	Phosphotransferase system cellobiose-specific component IIA
BF28_RS26940	COG3711	transcriptional antiterminator
BF28_RS26940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BF28_RS26955	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF28_RS26960	COG0604	alcohol dehydrogenase
BF28_RS26965	COG1316	TRANSCRIPTIONal
BF28_RS26975	COG0730	response to heat
BF28_RS26980	COG2210	Belongs to the sulfur carrier protein TusA family
BF28_RS26990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_RS26995	COG0425	Belongs to the sulfur carrier protein TusA family
BF28_RS27000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF28_RS27000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_RS27005	COG0425	Belongs to the sulfur carrier protein TusA family
BF28_RS27005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BF28_RS27010	COG1937	Protein conserved in bacteria
BF28_RS27015	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF28_RS27025	COG2719	SpoVR family
BF28_RS27030	COG0778	Nitroreductase
BF28_RS27070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF28_RS27090	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS27095	COG2252	PERMEase
BF28_RS27110	COG1846	Transcriptional regulator
BF28_RS27115	COG2814	Major facilitator Superfamily
BF28_RS27120	COG2205	protein histidine kinase activity
BF28_RS27160	COG0351	phosphomethylpyrimidine kinase
BF28_RS27165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BF28_RS27175	COG2104	thiamine diphosphate biosynthetic process
BF28_RS27180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_RS27185	COG0352	thiamine-phosphate diphosphorylase activity
BF28_RS27190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BF28_RS27195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_RS27200	COG1116	anion transmembrane transporter activity
BF28_RS27205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BF28_RS27230	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BF28_RS27350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF28_RS27360	COG0581	inorganic phosphate transmembrane transporter activity
BF28_RS27365	COG0573	inorganic phosphate transmembrane transporter activity
BF28_RS27370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BF28_RS27375	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF28_RS27375	COG1918	ferrous iron import across plasma membrane
BF28_RS27380	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF28_RS27385	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF28_RS27400	COG0531	amino acid
BF28_RS27405	COG0697	spore germination
BF28_RS27410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF28_RS27425	COG4990	cell redox homeostasis
BF28_RS27430	COG0833	amino acid
BF28_RS27435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BF28_RS27440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BF28_RS27455	COG0569	domain protein
BF28_RS27455	COG0475	glutathione-regulated potassium exporter activity
BF28_RS27465	COG2153	protein acetylation
BF28_RS27480	COG2252	PERMEase
BF28_RS27485	COG1113	amino acid transport
BF28_RS27500	COG1114	Component of the transport system for branched-chain amino acids
BF28_RS27505	COG3104	oligopeptide transport
BF28_RS27520	COG1476	TRANSCRIPTIONal
BF28_RS27525	COG1388	LysM domain
BF28_RS27525	COG3584	3D domain protein
BF28_RS27530	COG0840	transmembrane signaling receptor activity
BF28_RS27560	COG3568	Endonuclease Exonuclease Phosphatase
BF28_RS27585	COG1063	alcohol dehydrogenase
BF28_RS27610	COG1879	ABC-type sugar transport system periplasmic component
BF28_RS27615	COG1172	Belongs to the binding-protein-dependent transport system permease family
BF28_RS27630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF28_RS27635	COG1609	Transcriptional regulator
BF28_RS27640	COG0477	Major facilitator Superfamily
BF28_RS27645	COG1846	Transcriptional regulator
BF28_RS27650	COG2271	Major facilitator Superfamily
BF28_RS27660	COG4608	Belongs to the ABC transporter superfamily
BF28_RS27665	COG0601	transmembrane transport
BF28_RS27675	COG0747	negative chemotaxis
BF28_RS27690	COG0659	secondary active sulfate transmembrane transporter activity
BF28_RS27705	COG5002	protein histidine kinase activity
BF28_RS27710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BF28_RS27715	COG2378	regulation of single-species biofilm formation
BF28_RS27740	COG0833	amino acid
BF28_RS27745	COG0765	amino acid transport
BF28_RS27750	COG0765	amino acid transport
BF28_RS27755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_RS27760	COG1126	abc transporter atp-binding protein
BF28_RS27765	COG1115	amino acid carrier protein
BF28_RS27770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BF28_RS27780	COG0697	spore germination
BF28_RS27795	COG0366	Alpha amylase catalytic
BF28_RS27800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_RS27800	COG1263	PTS System
BF28_RS27805	COG2188	Transcriptional regulator
BF28_RS27810	COG0531	amino acid
BF28_RS27830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF28_RS27835	COG0714	Associated with various cellular activities
BF28_RS27840	COG4548	von Willebrand factor, type A
BF28_RS27850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BF28_RS27855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF28_RS27860	COG0156	8-amino-7-oxononanoate synthase activity
BF28_RS27865	COG2226	methyltransferase
BF28_RS27875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS27880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS27885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS27890	COG3104	oligopeptide transport
BF28_RS27905	COG1620	l-lactate permease
BF28_RS27910	COG1027	Aspartate ammonia-lyase
BF28_RS27915	COG1253	flavin adenine dinucleotide binding
BF28_RS27920	COG0346	lactoylglutathione lyase activity
BF28_RS27925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS27930	COG1316	TRANSCRIPTIONal
BF28_RS27935	COG2720	vancomycin resistance protein
BF28_RS27955	COG3227	Zinc metalloprotease (Elastase)
BF28_RS27965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF28_RS27970	COG2217	Heavy metal translocating P-type atpase
BF28_RS27975	COG0640	Transcriptional regulator
BF28_RS27980	COG0531	amino acid
BF28_RS27995	COG2427	Protein of unknown function (DUF1641)
BF28_RS28000	COG3383	formate dehydrogenase (NAD+) activity
BF28_RS28005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BF28_RS28010	COG0456	acetyltransferase
BF28_RS28010	COG0454	-acetyltransferase
BF28_RS28020	COG0745	RESPONSE REGULATOR receiver
BF28_RS28025	COG5002	protein histidine kinase activity
BF28_RS28035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BF28_RS28040	COG0697	spore germination
BF28_RS28050	COG0281	malic enzyme
BF28_RS28055	COG3493	citrate carrier protein
BF28_RS28060	COG4565	transcriptional regulatory protein
BF28_RS28065	COG3290	protein histidine kinase activity
BF28_RS28075	COG4990	cell redox homeostasis
BF28_RS28085	COG5002	protein histidine kinase activity
BF28_RS28090	COG0745	RESPONSE REGULATOR receiver
BF28_RS28095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BF28_RS28105	COG0395	ABC-type sugar transport system, permease component
BF28_RS28110	COG1175	transmembrane transport
BF28_RS28115	COG3842	ATPase activity
BF28_RS28120	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BF28_RS28140	COG2851	Citrate transporter
BF28_RS28150	COG4565	transcriptional regulatory protein
BF28_RS28155	COG3290	protein histidine kinase activity
BF28_RS28165	COG2268	Band 7 protein
BF28_RS28170	COG1585	Membrane protein implicated in regulation of membrane protease activity
BF28_RS28180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BF28_RS28185	COG0765	amino acid transport
BF28_RS28190	COG0765	amino acid transport
BF28_RS28195	COG1126	abc transporter atp-binding protein
BF28_RS28200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_RS28225	COG2766	serine protein kinase
BF28_RS28240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BF28_RS28250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF28_RS28260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BF28_RS28265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF28_RS28380	COG0735	belongs to the Fur family
BF28_RS28385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF28_RS28405	COG4555	ABC transporter
BF28_RS28415	COG0067	glutamate synthase
BF28_RS28415	COG0069	glutamate synthase activity
BF28_RS28415	COG0070	glutamate synthase
BF28_RS28420	COG4129	membrane
BF28_RS28425	COG1132	(ABC) transporter
BF28_RS28450	COG1194	a g-specific adenine glycosylase
BF28_RS28455	COG1988	membrane-bound metal-dependent
BF28_RS28485	COG1090	epimerase
BF28_RS28510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF28_RS28530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF28_RS28530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF28_RS28540	COG0463	Glycosyl transferase, family 2
BF28_RS28560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BF28_RS28565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_RS28565	COG1263	PTS System
BF28_RS28600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF28_RS28605	COG0833	amino acid
BF28_RS28615	COG3829	transcription factor binding
BF28_RS28630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF28_RS28635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BF28_RS28655	COG0535	radical SAM domain protein
BF28_RS28665	COG0387	Pfam Sodium calcium exchanger
BF28_RS28670	COG3871	stress protein (general stress protein 26)
BF28_RS28685	COG0586	Pfam SNARE associated Golgi protein
BF28_RS28695	COG0681	Belongs to the peptidase S26 family
BF28_RS28705	COG0697	spore germination
BF28_RS28710	COG2217	Heavy metal translocating P-type atpase
BF28_RS28715	COG1295	ribonuclease BN
BF28_RS28725	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF28_RS28740	COG3853	Toxic anion resistance protein (TelA)
BF28_RS28750	COG0861	Integral membrane protein TerC family
BF28_RS28755	COG2310	stress, protein
BF28_RS28760	COG2310	stress, protein
BF28_RS28765	COG2310	stress, protein
BF28_RS28795	COG2270	Major facilitator Superfamily
BF28_RS28840	COG0488	(ABC) transporter
BF28_RS28850	COG1116	anion transmembrane transporter activity
BF28_RS28860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BF28_RS28875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF28_RS28910	COG1263	PTS System
BF28_RS28910	COG2190	(PTS) system
BF28_RS28910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BF28_RS28915	COG0366	Alpha amylase catalytic
BF28_RS28920	COG0840	transmembrane signaling receptor activity
BF28_RS28925	COG0840	transmembrane signaling receptor activity
BF28_RS28935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF28_RS28940	COG0765	amino acid transport
BF28_RS28950	COG0723	plastoquinol--plastocyanin reductase activity
BF28_RS28950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF28_RS28955	COG2814	Major facilitator Superfamily
BF28_RS29010	COG0166	Belongs to the GPI family
BF28_RS29030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BF28_RS29035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS29040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF28_RS29060	COG0450	alkyl hydroperoxide reductase
BF28_RS29075	COG1473	amidohydrolase
BF28_RS29080	COG1757	Na H antiporter
BF28_RS29105	COG4807	Protein conserved in bacteria
BF28_RS29110	COG5002	protein histidine kinase activity
BF28_RS29120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF28_RS29125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF28_RS29130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BF28_RS29145	COG2309	aminopeptidase activity
BF28_RS29150	COG2076	Multidrug Resistance protein
BF28_RS29155	COG1012	belongs to the aldehyde dehydrogenase family
BF28_RS29165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BF28_RS29170	COG0546	phosphoglycolate phosphatase activity
BF28_RS29175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BF28_RS29180	COG1597	lipid kinase activity
BF28_RS29200	COG4682	membrane
BF28_RS29205	COG1846	Transcriptional regulator
BF28_RS29210	COG0003	Pfam Anion-transporting ATPase
BF28_RS29225	COG1464	Belongs to the NlpA lipoprotein family
BF28_RS29230	COG2011	ABC-type metal ion transport system permease component
BF28_RS29240	COG1335	isochorismatase
BF28_RS29260	COG4851	CamS sex pheromone cAM373 precursor
BF28_RS29270	COG0210	DNA helicase
BF28_RS29300	COG0151	Belongs to the GarS family
BF28_RS29310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF28_RS29320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF28_RS29335	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF28_RS29345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BF28_RS29350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BF28_RS29380	COG0697	spore germination
BF28_RS29400	COG0745	RESPONSE REGULATOR receiver
BF28_RS29405	COG2205	protein histidine kinase activity
BF28_RS29470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BF28_RS29495	COG5002	protein histidine kinase activity
BF28_RS29505	COG2252	PERMEase
BF28_RS29520	COG5444	nuclease activity
BF28_RS29535	COG1266	CAAX protease self-immunity
BF28_RS29550	COG0488	(ABC) transporter
BF28_RS29560	COG0456	acetyltransferase
BF28_RS29565	COG1214	PFAM Peptidase M22, glycoprotease
BF28_RS29570	COG0802	atpase or kinase
BF28_RS29665	COG2183	response to ionizing radiation
BF28_RS29670	COG2337	Toxic component of a toxin-antitoxin (TA) module
BF28_RS29675	COG0864	Transcriptional regulator
BF28_RS29680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF28_RS29685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BF28_RS29695	COG0457	Tetratricopeptide repeat
BF28_RS29695	COG0705	Rhomboid family
BF28_RS29700	COG4294	response to UV
BF28_RS29710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF28_RS29730	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF28_RS29735	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BF28_RS29770	COG0561	phosphatase activity
BF28_RS29775	COG4608	Belongs to the ABC transporter superfamily
BF28_RS29780	COG0444	Belongs to the ABC transporter superfamily
BF28_RS29785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_RS29790	COG0601	transmembrane transport
BF28_RS29795	COG0747	negative chemotaxis
BF28_RS29810	COG0488	(ABC) transporter
BF28_RS29835	COG5298	Protein conserved in bacteria
BF28_RS29845	COG0084	hydrolase, TatD family'
BF28_RS29860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF28_RS29870	COG1609	Transcriptional regulator
BF28_RS29880	COG0204	Acyl-transferase
BF28_RS29890	COG0697	spore germination
BF28_RS29915	COG1910	domain protein
BF28_RS29920	COG0725	ABC transporter, periplasmic molybdate-binding protein
BF28_RS29925	COG4149	molybdate abc transporter
BF28_RS29945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF28_RS29950	COG0656	L-ascorbic acid biosynthetic process
BF28_RS29955	COG4166	transmembrane transport
BF28_RS29960	COG4166	transmembrane transport
BF28_RS29970	COG1309	transcriptional regulator
BF28_RS29980	COG2207	Transcriptional regulator
BF28_RS29990	COG4166	transmembrane transport
BF28_RS29995	COG4608	Belongs to the ABC transporter superfamily
BF28_RS30000	COG0444	Belongs to the ABC transporter superfamily
BF28_RS30005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BF28_RS30010	COG0601	transmembrane transport
BF28_RS30025	COG2814	Major facilitator Superfamily
BF28_RS30035	COG2271	Major facilitator Superfamily
BF28_RS30040	COG0277	FAD linked oxidase domain protein
BF28_RS30050	COG0604	alcohol dehydrogenase
BF28_RS30055	COG1464	Belongs to the NlpA lipoprotein family
BF28_RS30065	COG2011	ABC-type metal ion transport system permease component
BF28_RS30070	COG1028	Short-chain dehydrogenase reductase Sdr
BF28_RS30100	COG1506	peptidase
BF28_RS30100	COG4946	Tricorn protease homolog
BF28_RS30100	COG0823	Involved in the tonB-independent uptake of proteins
BF28_RS30105	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF28_RS30125	COG0596	Alpha beta hydrolase
BF28_RS30200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF28_RS30310	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BF28_RS30315	COG0110	maltose O-acetyltransferase activity
BF28_RS30330	COG1620	l-lactate permease
BF28_RS30420	COG2376	Dihydroxyacetone kinase