locus-tag	class	description
FOC74_RS00005	COG1846	Transcriptional regulator
FOC74_RS00045	COG2217	Heavy metal translocating P-type atpase
FOC74_RS00050	COG1937	Protein conserved in bacteria
FOC74_RS00055	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC74_RS00055	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC74_RS00075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC74_RS00170	COG3118	belongs to the thioredoxin family
FOC74_RS00190	COG1126	abc transporter atp-binding protein
FOC74_RS00195	COG2304	oxidoreductase activity
FOC74_RS00200	COG2132	Multicopper oxidase
FOC74_RS00205	COG0745	RESPONSE REGULATOR receiver
FOC74_RS00210	COG5002	protein histidine kinase activity
FOC74_RS00220	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS00275	COG2918	glutathione biosynthetic process
FOC74_RS00275	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC74_RS00285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FOC74_RS00295	COG1733	regulation of RNA biosynthetic process
FOC74_RS00310	COG0697	spore germination
FOC74_RS00335	COG2323	membrane
FOC74_RS00350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS00385	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS00425	COG2207	Transcriptional regulator
FOC74_RS00425	COG3708	Transcriptional regulator
FOC74_RS00445	COG1335	isochorismatase
FOC74_RS00475	COG0546	phosphoglycolate phosphatase activity
FOC74_RS00515	COG3344	reverse transcriptase
FOC74_RS00535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS00585	COG1780	Probably involved in ribonucleotide reductase function
FOC74_RS00740	COG1466	dna polymerase III delta subunit
FOC74_RS00750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC74_RS00765	COG3344	reverse transcriptase
FOC74_RS00795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC74_RS00890	COG3344	reverse transcriptase
FOC74_RS00910	COG0741	lytic transglycosylase activity
FOC74_RS00910	COG0791	NLP P60 protein
FOC74_RS00945	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC74_RS01015	COG2318	DinB family
FOC74_RS01175	COG1674	ftsk spoiiie
FOC74_RS01220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC74_RS01230	COG0210	DNA helicase
FOC74_RS01235	COG0470	DNA polymerase III
FOC74_RS01255	COG2304	oxidoreductase activity
FOC74_RS01260	COG2002	toxin-antitoxin pair type II binding
FOC74_RS01330	COG0798	PFAM Bile acid sodium symporter
FOC74_RS01335	COG0640	Transcriptional regulator
FOC74_RS01350	COG0523	cobalamin synthesis protein
FOC74_RS01355	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC74_RS01365	COG3620	sequence-specific DNA binding
FOC74_RS01370	COG0306	phosphate transporter
FOC74_RS01375	COG0640	Transcriptional regulator
FOC74_RS01455	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOC74_RS01555	COG0305	Participates in initiation and elongation during chromosome replication
FOC74_RS01575	COG3723	Recombinational DNA repair protein, rece pathway
FOC74_RS01580	COG5377	YqaJ viral recombinase family
FOC74_RS01605	COG1396	sequence-specific DNA binding
FOC74_RS01640	COG1192	Involved in chromosome partitioning
FOC74_RS01680	COG0322	excinuclease ABC activity
FOC74_RS01695	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS01785	COG4653	Phage capsid family
FOC74_RS01790	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOC74_RS01795	COG2369	cell adhesion
FOC74_RS01800	COG5518	Phage portal protein
FOC74_RS01810	COG5484	DNA packaging
FOC74_RS01825	COG3409	Peptidoglycan-binding domain 1 protein
FOC74_RS01825	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS01845	COG2207	Transcriptional regulator
FOC74_RS01845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS01850	COG0662	Cupin 2, conserved barrel domain protein
FOC74_RS01865	COG1595	DNA-templated transcription, initiation
FOC74_RS01885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC74_RS01900	COG0531	amino acid
FOC74_RS01905	COG1522	sequence-specific DNA binding
FOC74_RS01910	COG1335	isochorismatase
FOC74_RS01920	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC74_RS01925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC74_RS01935	COG1760	l-serine dehydratase
FOC74_RS01940	COG1760	l-serine dehydratase
FOC74_RS01945	COG0814	amino acid
FOC74_RS01955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS01980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC74_RS02000	COG0457	Tetratricopeptide repeat
FOC74_RS02005	COG1609	Transcriptional regulator
FOC74_RS02010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC74_RS02015	COG0561	phosphatase activity
FOC74_RS02020	COG0673	inositol 2-dehydrogenase activity
FOC74_RS02025	COG0738	Major facilitator superfamily
FOC74_RS02045	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC74_RS02055	COG0583	DNA-binding transcription factor activity
FOC74_RS02065	COG1139	Iron-sulfur cluster binding protein
FOC74_RS02070	COG1556	Lactate utilization protein
FOC74_RS02075	COG2271	Major facilitator Superfamily
FOC74_RS02080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS02090	COG3850	Histidine kinase
FOC74_RS02090	COG5002	protein histidine kinase activity
FOC74_RS02105	COG0577	efflux transmembrane transporter activity
FOC74_RS02110	COG1136	(ABC) transporter
FOC74_RS02125	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC74_RS02145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS02155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC74_RS02160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS02185	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC74_RS02210	COG5002	protein histidine kinase activity
FOC74_RS02210	COG3850	Histidine kinase
FOC74_RS02215	COG0745	RESPONSE REGULATOR receiver
FOC74_RS02240	COG2814	Major facilitator Superfamily
FOC74_RS02295	COG2169	Transcriptional regulator
FOC74_RS02315	COG0346	lactoylglutathione lyase activity
FOC74_RS02330	COG1522	sequence-specific DNA binding
FOC74_RS02340	COG1309	transcriptional regulator
FOC74_RS02345	COG3320	Male sterility
FOC74_RS02345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC74_RS02355	COG0456	acetyltransferase
FOC74_RS02360	COG0745	RESPONSE REGULATOR receiver
FOC74_RS02365	COG5002	protein histidine kinase activity
FOC74_RS02385	COG0640	Transcriptional regulator
FOC74_RS02390	COG0798	PFAM Bile acid sodium symporter
FOC74_RS02415	COG1136	(ABC) transporter
FOC74_RS02420	COG4641	Protein conserved in bacteria
FOC74_RS02425	COG2267	carboxylic ester hydrolase activity
FOC74_RS02430	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC74_RS02445	COG5609	conserved protein (DUF2294)
FOC74_RS02450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC74_RS02460	COG0288	reversible hydration of carbon dioxide
FOC74_RS02465	COG0415	Belongs to the DNA photolyase family
FOC74_RS02500	COG0598	Magnesium transport protein CorA
FOC74_RS02505	COG1846	Transcriptional regulator
FOC74_RS02510	COG0583	DNA-binding transcription factor activity
FOC74_RS02530	COG1335	isochorismatase
FOC74_RS02535	COG2267	carboxylic ester hydrolase activity
FOC74_RS02540	COG0753	catalase activity
FOC74_RS02545	COG0737	Belongs to the 5'-nucleotidase family
FOC74_RS02555	COG1115	amino acid carrier protein
FOC74_RS02560	COG2066	Belongs to the glutaminase family
FOC74_RS02565	COG4191	Histidine kinase
FOC74_RS02570	COG0784	Response regulator, receiver
FOC74_RS02575	COG0697	spore germination
FOC74_RS02580	COG0531	amino acid
FOC74_RS02600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC74_RS02605	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS02610	COG0531	amino acid
FOC74_RS02615	COG0322	excinuclease ABC activity
FOC74_RS02625	COG1396	sequence-specific DNA binding
FOC74_RS02630	COG0252	asparaginase activity
FOC74_RS02635	COG1027	Aspartate ammonia-lyase
FOC74_RS02645	COG1063	alcohol dehydrogenase
FOC74_RS02675	COG1113	amino acid transport
FOC74_RS02680	COG1280	lysine exporter protein (LysE YggA)
FOC74_RS02685	COG3403	YqcI/YcgG family
FOC74_RS02690	COG5577	PFAM Coat F domain
FOC74_RS02705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS02710	COG3848	Pyruvate phosphate dikinase
FOC74_RS02710	COG0574	Belongs to the PEP-utilizing enzyme family
FOC74_RS02725	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC74_RS02755	COG1960	acyl-CoA dehydrogenase activity
FOC74_RS02765	COG0640	Transcriptional regulator
FOC74_RS02770	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS02785	COG1414	Transcriptional regulator
FOC74_RS02790	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC74_RS02795	COG1984	allophanate hydrolase subunit 2
FOC74_RS02825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC74_RS02865	COG4335	DNA alkylation repair
FOC74_RS02875	COG0833	amino acid
FOC74_RS02885	COG0730	response to heat
FOC74_RS02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS02950	COG0456	acetyltransferase
FOC74_RS02955	COG2207	Transcriptional regulator
FOC74_RS02980	COG1136	(ABC) transporter
FOC74_RS02990	COG1725	Transcriptional regulator
FOC74_RS03020	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC74_RS03025	COG2814	Major facilitator Superfamily
FOC74_RS03030	COG2508	Transcriptional regulator
FOC74_RS03040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC74_RS03055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC74_RS03060	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC74_RS03065	COG2723	6-phospho-beta-galactosidase activity
FOC74_RS03070	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC74_RS03075	COG1024	Enoyl-CoA hydratase
FOC74_RS03080	COG0183	Belongs to the thiolase family
FOC74_RS03085	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS03090	COG0824	Thioesterase
FOC74_RS03095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC74_RS03105	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC74_RS03125	COG1846	Transcriptional regulator
FOC74_RS03130	COG0778	Nitroreductase
FOC74_RS03160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC74_RS03170	COG0753	catalase activity
FOC74_RS03175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC74_RS03185	COG0463	Glycosyl transferase, family 2
FOC74_RS03205	COG0463	Glycosyl transferase, family 2
FOC74_RS03230	COG0714	Associated with various cellular activities
FOC74_RS03250	COG0346	lactoylglutathione lyase activity
FOC74_RS03255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS03265	COG3279	Response regulator of the LytR AlgR family
FOC74_RS03275	COG4377	Putative membrane peptidase family (DUF2324)
FOC74_RS03290	COG3655	Transcriptional regulator
FOC74_RS03300	COG1785	Belongs to the alkaline phosphatase family
FOC74_RS03305	COG3239	Fatty acid desaturase
FOC74_RS03310	COG1690	Belongs to the RtcB family
FOC74_RS03315	COG0833	amino acid
FOC74_RS03320	COG1414	Transcriptional regulator
FOC74_RS03325	COG4187	Peptidase family M20/M25/M40
FOC74_RS03350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC74_RS03355	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC74_RS03365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS03385	COG2329	Antibiotic biosynthesis monooxygenase
FOC74_RS03420	COG1070	Carbohydrate kinase
FOC74_RS03425	COG2390	Transcriptional regulator
FOC74_RS03435	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC74_RS03445	COG1879	ABC-type sugar transport system periplasmic component
FOC74_RS03460	COG3829	transcription factor binding
FOC74_RS03460	COG3290	protein histidine kinase activity
FOC74_RS03470	COG1024	Enoyl-CoA hydratase
FOC74_RS03475	COG2610	gluconate transmembrane transporter activity
FOC74_RS03485	COG1388	LysM domain
FOC74_RS03485	COG3584	3D domain protein
FOC74_RS03520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC74_RS03520	COG1605	Chorismate mutase
FOC74_RS03530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC74_RS03535	COG0287	Prephenate dehydrogenase
FOC74_RS03550	COG1309	transcriptional regulator
FOC74_RS03555	COG2409	Drug exporters of the RND superfamily
FOC74_RS03555	COG1033	growth of symbiont in host cell
FOC74_RS03565	COG0488	(ABC) transporter
FOC74_RS03570	COG1368	sulfuric ester hydrolase activity
FOC74_RS03575	COG0861	Integral membrane protein TerC family
FOC74_RS03595	COG4912	Dna alkylation repair
FOC74_RS03615	COG2318	DinB family
FOC74_RS03620	COG0697	spore germination
FOC74_RS03645	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC74_RS03690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC74_RS03695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC74_RS03700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC74_RS03710	COG0628	permease
FOC74_RS03760	COG1131	(ABC) transporter
FOC74_RS03775	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC74_RS03785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC74_RS03790	COG0436	Aminotransferase
FOC74_RS03830	COG2226	methyltransferase
FOC74_RS03845	COG2261	transglycosylase associated protein
FOC74_RS03865	COG0477	Major facilitator Superfamily
FOC74_RS03865	COG2814	Major facilitator Superfamily
FOC74_RS03870	COG4533	DNA binding
FOC74_RS03875	COG0789	Transcriptional regulator
FOC74_RS03880	COG1664	Polymer-forming cytoskeletal
FOC74_RS03890	COG2814	Major facilitator Superfamily
FOC74_RS03910	COG1307	EDD domain protein, DegV family
FOC74_RS03920	COG1164	Oligoendopeptidase f
FOC74_RS03955	COG0745	RESPONSE REGULATOR receiver
FOC74_RS03960	COG5002	protein histidine kinase activity
FOC74_RS03965	COG2936	dipeptidyl-peptidase activity
FOC74_RS04010	COG4948	Mandelate Racemase Muconate Lactonizing
FOC74_RS04020	COG4166	transmembrane transport
FOC74_RS04025	COG0519	Catalyzes the synthesis of GMP from XMP
FOC74_RS04030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC74_RS04045	COG0586	Pfam SNARE associated Golgi protein
FOC74_RS04085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC74_RS04090	COG3938	Belongs to the proline racemase family
FOC74_RS04100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC74_RS04105	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS04110	COG1115	amino acid carrier protein
FOC74_RS04115	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC74_RS04130	COG3397	chitin binding
FOC74_RS04155	COG4637	Psort location Cytoplasmic, score
FOC74_RS04175	COG0514	ATP-dependent DNA helicase (RecQ)
FOC74_RS04180	COG2105	PFAM AIG2 family protein
FOC74_RS04195	COG3973	AAA domain
FOC74_RS04245	COG0658	competence protein
FOC74_RS04245	COG2333	competence protein COMEC
FOC74_RS04270	COG2226	methyltransferase
FOC74_RS04275	COG2205	protein histidine kinase activity
FOC74_RS04290	COG1819	glycosyl
FOC74_RS04295	COG3397	chitin binding
FOC74_RS04300	COG2153	protein acetylation
FOC74_RS04305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC74_RS04330	COG4175	Glycine betaine
FOC74_RS04330	COG0517	IMP dehydrogenase activity
FOC74_RS04335	COG4176	ABC-type proline glycine betaine transport system permease component
FOC74_RS04375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC74_RS04375	COG0456	acetyltransferase
FOC74_RS04380	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS04390	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC74_RS04395	COG0022	dehydrogenase e1 component
FOC74_RS04400	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC74_RS04405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC74_RS04425	COG1349	DNA-binding transcription factor activity
FOC74_RS04445	COG3284	Transcriptional regulator
FOC74_RS04465	COG1309	transcriptional regulator
FOC74_RS04500	COG2959	enzyme of heme biosynthesis
FOC74_RS04515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS04550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS04555	COG0697	spore germination
FOC74_RS04565	COG0201	protein transport
FOC74_RS04585	COG3227	Zinc metalloprotease (Elastase)
FOC74_RS04590	COG1523	belongs to the glycosyl hydrolase 13 family
FOC74_RS04605	COG0076	glutamate decarboxylase activity
FOC74_RS04615	COG1073	alpha beta
FOC74_RS04630	COG1011	Hydrolase
FOC74_RS04655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC74_RS04695	COG0322	excinuclease ABC activity
FOC74_RS04710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC74_RS04735	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC74_RS04755	COG3878	Protein conserved in bacteria
FOC74_RS04790	COG1051	belongs to the nudix hydrolase family
FOC74_RS04795	COG0592	DNA-directed DNA polymerase activity
FOC74_RS04815	COG2223	nitrite transmembrane transporter activity
FOC74_RS04855	COG0697	spore germination
FOC74_RS04860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS04875	COG0584	glycerophosphoryl diester phosphodiesterase
FOC74_RS04890	COG2814	Major facilitator Superfamily
FOC74_RS04920	COG0693	protein deglycase activity
FOC74_RS04955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC74_RS04970	COG0671	phosphoesterase, PA-phosphatase related
FOC74_RS04975	COG0604	alcohol dehydrogenase
FOC74_RS04990	COG2205	protein histidine kinase activity
FOC74_RS05015	COG1794	racemase activity, acting on amino acids and derivatives
FOC74_RS05020	COG1819	glycosyl
FOC74_RS05030	COG5002	protein histidine kinase activity
FOC74_RS05035	COG0561	phosphatase activity
FOC74_RS05070	COG2124	cytochrome p450
FOC74_RS05115	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS05220	COG0582	viral genome integration into host DNA
FOC74_RS05265	COG0662	Cupin 2, conserved barrel domain protein
FOC74_RS05310	COG1484	DNA-dependent DNA replication
FOC74_RS05355	COG0582	viral genome integration into host DNA
FOC74_RS05390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC74_RS05400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS05405	COG0460	homoserine dehydrogenase
FOC74_RS05425	COG0577	efflux transmembrane transporter activity
FOC74_RS05430	COG1136	(ABC) transporter
FOC74_RS05455	COG2205	protein histidine kinase activity
FOC74_RS05460	COG0745	RESPONSE REGULATOR receiver
FOC74_RS05470	COG3773	Cell wall hydrolase
FOC74_RS05475	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FOC74_RS05485	COG3386	PFAM SMP-30 Gluconolaconase
FOC74_RS05505	COG1063	alcohol dehydrogenase
FOC74_RS05520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS05540	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC74_RS05560	COG2814	Major facilitator Superfamily
FOC74_RS05600	COG3227	Zinc metalloprotease (Elastase)
FOC74_RS05620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC74_RS05645	COG1686	Belongs to the peptidase S11 family
FOC74_RS05650	COG2318	DinB family
FOC74_RS05660	COG0572	uridine kinase
FOC74_RS05665	COG1247	-acetyltransferase
FOC74_RS05675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC74_RS05680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC74_RS05685	COG1024	Enoyl-CoA hydratase
FOC74_RS05690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC74_RS05695	COG0511	ligase activity, forming carbon-carbon bonds
FOC74_RS05700	COG0439	Biotin carboxylase
FOC74_RS05705	COG1960	acyl-CoA dehydrogenase activity
FOC74_RS05720	COG1309	transcriptional regulator
FOC74_RS05730	COG1131	(ABC) transporter
FOC74_RS05745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC74_RS05780	COG1309	transcriptional regulator
FOC74_RS05800	COG1876	peptidase activity
FOC74_RS05815	COG1476	TRANSCRIPTIONal
FOC74_RS05820	COG0457	Tetratricopeptide repeat
FOC74_RS05830	COG0737	Belongs to the 5'-nucleotidase family
FOC74_RS05845	COG3718	enzyme involved in inositol metabolism
FOC74_RS05875	COG0673	inositol 2-dehydrogenase activity
FOC74_RS05880	COG2814	Major facilitator Superfamily
FOC74_RS05885	COG1609	Transcriptional regulator
FOC74_RS05890	COG0671	phosphoesterase, PA-phosphatase related
FOC74_RS05895	COG2367	Beta-lactamase
FOC74_RS05915	COG1595	DNA-templated transcription, initiation
FOC74_RS05930	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC74_RS05965	COG1846	Transcriptional regulator
FOC74_RS05970	COG3961	Belongs to the TPP enzyme family
FOC74_RS05985	COG0500	methyltransferase
FOC74_RS05985	COG3615	Tellurite resistance protein tehB
FOC74_RS05990	COG1136	(ABC) transporter
FOC74_RS05990	COG0577	efflux transmembrane transporter activity
FOC74_RS06005	COG1309	transcriptional regulator
FOC74_RS06035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS06070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC74_RS06080	COG2971	BadF BadG BcrA BcrD
FOC74_RS06105	COG1649	PFAM Uncharacterised BCR, COG1649
FOC74_RS06130	COG1595	DNA-templated transcription, initiation
FOC74_RS06135	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC74_RS06145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC74_RS06175	COG1396	sequence-specific DNA binding
FOC74_RS06195	COG1132	(ABC) transporter
FOC74_RS06200	COG1132	(ABC) transporter
FOC74_RS06215	COG2258	MOSC domain
FOC74_RS06220	COG0583	DNA-binding transcription factor activity
FOC74_RS06235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC74_RS06240	COG0583	DNA-binding transcription factor activity
FOC74_RS06285	COG0561	phosphatase activity
FOC74_RS06290	COG0010	Belongs to the arginase family
FOC74_RS06305	COG1278	Cold shock
FOC74_RS06315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS06355	COG1247	-acetyltransferase
FOC74_RS06390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS06425	COG2226	methyltransferase
FOC74_RS06445	COG0596	Alpha beta hydrolase
FOC74_RS06455	COG1136	(ABC) transporter
FOC74_RS06460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC74_RS06465	COG1187	pseudouridine synthase activity
FOC74_RS06470	COG2329	Antibiotic biosynthesis monooxygenase
FOC74_RS06485	COG1115	amino acid carrier protein
FOC74_RS06495	COG2318	DinB family
FOC74_RS06505	COG0776	regulation of translation
FOC74_RS06520	COG2814	Major facilitator Superfamily
FOC74_RS06525	COG3251	PFAM MbtH domain protein
FOC74_RS06530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC74_RS06535	COG1535	isochorismatase
FOC74_RS06535	COG3433	isochorismatase activity
FOC74_RS06540	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC74_RS06545	COG1169	isochorismate synthase
FOC74_RS06550	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS06555	COG2223	nitrite transmembrane transporter activity
FOC74_RS06575	COG0419	ATPase involved in DNA repair
FOC74_RS06580	COG0420	3'-5' exonuclease activity
FOC74_RS06595	COG1024	Enoyl-CoA hydratase
FOC74_RS06600	COG1280	lysine exporter protein (LysE YggA)
FOC74_RS06610	COG2084	Dehydrogenase
FOC74_RS06615	COG1960	acyl-CoA dehydrogenase activity
FOC74_RS06620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC74_RS06625	COG2079	MmgE PrpD family protein
FOC74_RS06630	COG0372	Belongs to the citrate synthase family
FOC74_RS06635	COG4841	protein insertion into membrane
FOC74_RS06645	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC74_RS06645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC74_RS06685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC74_RS06775	COG1787	Restriction endonuclease
FOC74_RS06775	COG1715	Restriction endonuclease
FOC74_RS06805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC74_RS06810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC74_RS06815	COG0671	phosphoesterase, PA-phosphatase related
FOC74_RS06820	COG4326	sporulation control protein
FOC74_RS06860	COG1509	lysine 2,3-aminomutase activity
FOC74_RS06865	COG3829	transcription factor binding
FOC74_RS06870	COG0456	acetyltransferase
FOC74_RS06875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC74_RS06880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC74_RS06885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC74_RS06890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC74_RS06905	COG5506	Protein of unknown function (DUF1694)
FOC74_RS06910	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS06915	COG1253	flavin adenine dinucleotide binding
FOC74_RS06950	COG1174	glycine betaine transport
FOC74_RS06955	COG0517	IMP dehydrogenase activity
FOC74_RS06955	COG1125	glycine betaine transport
FOC74_RS06985	COG1070	Carbohydrate kinase
FOC74_RS06990	COG1070	Carbohydrate kinase
FOC74_RS07015	COG1064	alcohol dehydrogenase
FOC74_RS07025	COG2197	response regulator
FOC74_RS07030	COG2203	Gaf domain
FOC74_RS07030	COG4585	Histidine kinase
FOC74_RS07035	COG0668	transmembrane transport
FOC74_RS07040	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC74_RS07045	COG1051	belongs to the nudix hydrolase family
FOC74_RS07050	COG1335	isochorismatase
FOC74_RS07070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC74_RS07075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS07090	COG0367	asparagine synthase
FOC74_RS07095	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC74_RS07100	COG1999	signal sequence binding
FOC74_RS07105	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC74_RS07110	COG1307	EDD domain protein, DegV family
FOC74_RS07120	COG0805	protein transport
FOC74_RS07130	COG1272	protein, Hemolysin III
FOC74_RS07135	COG0204	Acyl-transferase
FOC74_RS07145	COG0768	penicillin binding
FOC74_RS07160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC74_RS07180	COG0546	phosphoglycolate phosphatase activity
FOC74_RS07190	COG4473	ABC transporter
FOC74_RS07195	COG1131	(ABC) transporter
FOC74_RS07205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC74_RS07210	COG0456	acetyltransferase
FOC74_RS07225	COG1454	alcohol dehydrogenase
FOC74_RS07230	COG2610	gluconate transmembrane transporter activity
FOC74_RS07255	COG0733	neurotransmitter:sodium symporter activity
FOC74_RS07270	COG3850	Histidine kinase
FOC74_RS07270	COG5002	protein histidine kinase activity
FOC74_RS07275	COG0745	RESPONSE REGULATOR receiver
FOC74_RS07280	COG0471	metal ion transport
FOC74_RS07285	COG1929	Belongs to the glycerate kinase type-1 family
FOC74_RS07330	COG1674	ftsk spoiiie
FOC74_RS07350	COG0017	Asparaginyl-tRNA synthetase
FOC74_RS07370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC74_RS07390	COG0018	arginyl-trna synthetase
FOC74_RS07420	COG1413	lyase activity
FOC74_RS07425	COG3344	reverse transcriptase
FOC74_RS07430	COG0629	single-stranded DNA binding
FOC74_RS07445	COG0488	(ABC) transporter
FOC74_RS07450	COG1418	mRNA catabolic process
FOC74_RS07475	COG2359	stage V sporulation protein S
FOC74_RS07510	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC74_RS07515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC74_RS07520	COG2146	nitrite reductase [NAD(P)H] activity
FOC74_RS07525	COG1587	Uroporphyrinogen-III synthase
FOC74_RS07525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC74_RS07535	COG1648	precorrin-2 dehydrogenase activity
FOC74_RS07545	COG2223	nitrite transmembrane transporter activity
FOC74_RS07555	COG0314	molybdopterin synthase activity
FOC74_RS07560	COG0303	'Molybdopterin
FOC74_RS07565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC74_RS07570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC74_RS07575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC74_RS07585	COG1335	isochorismatase
FOC74_RS07590	COG1764	response to oxidative stress
FOC74_RS07595	COG4918	Iron-sulphur cluster biosynthesis
FOC74_RS07600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC74_RS07605	COG3118	belongs to the thioredoxin family
FOC74_RS07610	COG1959	2 iron, 2 sulfur cluster binding
FOC74_RS07620	COG2181	nitrate reductase activity
FOC74_RS07625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC74_RS07630	COG1140	nitrate reductase beta subunit
FOC74_RS07635	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC74_RS07640	COG0714	Associated with various cellular activities
FOC74_RS07645	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC74_RS07650	COG1305	Transglutaminase-like
FOC74_RS07655	COG0386	Belongs to the glutathione peroxidase family
FOC74_RS07675	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC74_RS07690	COG1595	DNA-templated transcription, initiation
FOC74_RS07695	COG0604	alcohol dehydrogenase
FOC74_RS07705	COG0346	lactoylglutathione lyase activity
FOC74_RS07730	COG2226	methyltransferase
FOC74_RS07755	COG3874	Sporulation protein YtfJ
FOC74_RS07765	COG3344	reverse transcriptase
FOC74_RS07825	COG0456	acetyltransferase
FOC74_RS07855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS07860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS07865	COG1819	glycosyl
FOC74_RS07880	COG4106	trans-aconitate 2-methyltransferase activity
FOC74_RS07885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC74_RS07895	COG0561	phosphatase activity
FOC74_RS07915	COG2211	Major facilitator Superfamily
FOC74_RS07920	COG0154	amidase activity
FOC74_RS07930	COG1876	peptidase activity
FOC74_RS07940	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS07960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC74_RS07965	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS07980	COG1253	flavin adenine dinucleotide binding
FOC74_RS07985	COG2839	Protein conserved in bacteria
FOC74_RS07990	COG0702	epimerase
FOC74_RS08005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC74_RS08015	COG1607	acyl-coa hydrolase
FOC74_RS08020	COG3689	TIGRFAM TIGR03943 family protein
FOC74_RS08025	COG0701	Predicted permease
FOC74_RS08035	COG2244	polysaccharide biosynthetic process
FOC74_RS08040	COG0586	Pfam SNARE associated Golgi protein
FOC74_RS08045	COG1051	belongs to the nudix hydrolase family
FOC74_RS08050	COG5337	Spore coat protein CotH
FOC74_RS08060	COG0406	alpha-ribazole phosphatase activity
FOC74_RS08075	COG4166	transmembrane transport
FOC74_RS08085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC74_RS08095	COG0702	epimerase
FOC74_RS08105	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC74_RS08105	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC74_RS08160	COG0456	acetyltransferase
FOC74_RS08165	COG0523	cobalamin synthesis protein
FOC74_RS08170	COG4989	oxidoreductase activity
FOC74_RS08180	COG1231	oxidoreductase activity
FOC74_RS08190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC74_RS08205	COG0783	Belongs to the Dps family
FOC74_RS08210	COG3949	Membrane
FOC74_RS08225	COG0840	transmembrane signaling receptor activity
FOC74_RS08250	COG2814	Major facilitator Superfamily
FOC74_RS08255	COG0667	Aldo Keto reductase
FOC74_RS08260	COG0640	Transcriptional regulator
FOC74_RS08265	COG1404	Belongs to the peptidase S8 family
FOC74_RS08270	COG2002	toxin-antitoxin pair type II binding
FOC74_RS08275	COG0577	efflux transmembrane transporter activity
FOC74_RS08310	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC74_RS08320	COG1279	arginine transmembrane transporter activity
FOC74_RS08325	COG2814	Major facilitator Superfamily
FOC74_RS08335	COG1082	Xylose isomerase domain protein TIM barrel
FOC74_RS08350	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS08355	COG4264	IucA IucC family
FOC74_RS08365	COG1247	-acetyltransferase
FOC74_RS08370	COG1285	pathogenesis
FOC74_RS08385	COG5002	protein histidine kinase activity
FOC74_RS08390	COG0745	RESPONSE REGULATOR receiver
FOC74_RS08400	COG1316	TRANSCRIPTIONal
FOC74_RS08425	COG0460	homoserine dehydrogenase
FOC74_RS08440	COG5658	integral membrane protein
FOC74_RS08460	COG0300	oxidoreductase activity
FOC74_RS08470	COG5002	protein histidine kinase activity
FOC74_RS08475	COG0745	RESPONSE REGULATOR receiver
FOC74_RS08480	COG1132	(ABC) transporter
FOC74_RS08490	COG0791	NLP P60 protein
FOC74_RS08490	COG1388	LysM domain
FOC74_RS08505	COG1686	Belongs to the peptidase S11 family
FOC74_RS08525	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC74_RS08530	COG4988	ABC transporter
FOC74_RS08535	COG1294	oxidase, subunit
FOC74_RS08540	COG1271	oxidase subunit
FOC74_RS08570	COG0583	DNA-binding transcription factor activity
FOC74_RS08590	COG0411	ABC transporter
FOC74_RS08600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS08605	COG2030	dehydratase
FOC74_RS08610	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS08625	COG0523	cobalamin synthesis protein
FOC74_RS08630	COG1231	oxidoreductase activity
FOC74_RS08640	COG0628	permease
FOC74_RS08655	COG0778	Nitroreductase
FOC74_RS08660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC74_RS08665	COG1959	2 iron, 2 sulfur cluster binding
FOC74_RS08670	COG0583	DNA-binding transcription factor activity
FOC74_RS08675	COG0697	spore germination
FOC74_RS08680	COG4549	nuclear export factor GLE1
FOC74_RS08685	COG2372	response to copper ion
FOC74_RS08685	COG1276	copper resistance
FOC74_RS08695	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS08700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC74_RS08730	COG2132	Multicopper oxidase
FOC74_RS08735	COG0006	proline dipeptidase activity
FOC74_RS08760	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC74_RS08770	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC74_RS08775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS08785	COG2390	Transcriptional regulator
FOC74_RS08810	COG0531	amino acid
FOC74_RS08815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC74_RS08830	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC74_RS08850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS08880	COG4166	transmembrane transport
FOC74_RS08900	COG0427	acetyl-CoA hydrolase
FOC74_RS08905	COG3279	Response regulator of the LytR AlgR family
FOC74_RS08915	COG3384	dioxygenase
FOC74_RS08920	COG2814	Major facilitator Superfamily
FOC74_RS08945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC74_RS08955	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC74_RS08960	COG0440	acetolactate synthase activity
FOC74_RS08965	COG0028	Belongs to the TPP enzyme family
FOC74_RS08970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC74_RS08980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC74_RS08995	COG2323	membrane
FOC74_RS09000	COG5566	PFAM Mor transcription activator
FOC74_RS09010	COG0733	neurotransmitter:sodium symporter activity
FOC74_RS09015	COG2244	polysaccharide biosynthetic process
FOC74_RS09030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC74_RS09035	COG2223	nitrite transmembrane transporter activity
FOC74_RS09040	COG4166	transmembrane transport
FOC74_RS09045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC74_RS09055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS09060	COG0477	Major facilitator Superfamily
FOC74_RS09070	COG1966	Carbon starvation protein
FOC74_RS09085	COG2814	Major facilitator Superfamily
FOC74_RS09095	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS09100	COG1051	belongs to the nudix hydrolase family
FOC74_RS09155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC74_RS09160	COG0784	Response regulator, receiver
FOC74_RS09165	COG4191	Histidine kinase
FOC74_RS09170	COG0281	malic enzyme
FOC74_RS09175	COG1027	Aspartate ammonia-lyase
FOC74_RS09185	COG0528	UMP kinase activity
FOC74_RS09190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC74_RS09205	COG1131	(ABC) transporter
FOC74_RS09240	COG2733	membrane
FOC74_RS09270	COG0785	Cytochrome C biogenesis protein
FOC74_RS09290	COG3340	Belongs to the peptidase S51 family
FOC74_RS09295	COG0534	Mate efflux family protein
FOC74_RS09315	COG0114	fumarate hydratase activity
FOC74_RS09325	COG0789	Transcriptional regulator
FOC74_RS09330	COG1757	Na H antiporter
FOC74_RS09335	COG0438	transferase activity, transferring glycosyl groups
FOC74_RS09335	COG1216	Glycosyl transferase, family 2
FOC74_RS09345	COG0701	Predicted permease
FOC74_RS09350	COG0523	cobalamin synthesis protein
FOC74_RS09355	COG0697	spore germination
FOC74_RS09360	COG1802	Transcriptional regulator
FOC74_RS09390	COG0367	asparagine synthase
FOC74_RS09400	COG1846	Transcriptional regulator
FOC74_RS09420	COG0406	alpha-ribazole phosphatase activity
FOC74_RS09430	COG1686	Belongs to the peptidase S11 family
FOC74_RS09460	COG1234	tRNA 3'-trailer cleavage
FOC74_RS09475	COG3842	ATPase activity
FOC74_RS09480	COG0583	DNA-binding transcription factor activity
FOC74_RS09505	COG2329	Antibiotic biosynthesis monooxygenase
FOC74_RS09540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC74_RS09545	COG4786	Flagellar basal body rod
FOC74_RS09550	COG1419	protein localization to endoplasmic reticulum
FOC74_RS09555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC74_RS09560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC74_RS09570	COG1987	bacterial-type flagellum assembly
FOC74_RS09575	COG1338	Plays a role in the flagellum-specific transport system
FOC74_RS09585	COG1776	CheC inhibitor of MCP methylation
FOC74_RS09585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC74_RS09590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC74_RS09600	COG0741	lytic transglycosylase activity
FOC74_RS09605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC74_RS09610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC74_RS09620	COG0784	Response regulator, receiver
FOC74_RS09620	COG0835	chemotaxis
FOC74_RS09655	COG1157	protein secretion by the type III secretion system
FOC74_RS09665	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC74_RS09670	COG1766	The M ring may be actively involved in energy transduction
FOC74_RS09680	COG1558	bacterial-type flagellum-dependent cell motility
FOC74_RS09685	COG1815	bacterial-type flagellum-dependent cell motility
FOC74_RS09700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC74_RS09705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC74_RS09710	COG1256	bacterial-type flagellum assembly
FOC74_RS09730	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC74_RS09745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC74_RS09745	COG1776	CheC inhibitor of MCP methylation
FOC74_RS09750	COG0643	Histidine kinase
FOC74_RS09750	COG2198	Histidine kinase
FOC74_RS09755	COG2201	protein-glutamate methylesterase activity
FOC74_RS09760	COG1360	Flagellar Motor Protein
FOC74_RS09765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC74_RS09775	COG1923	regulation of RNA biosynthetic process
FOC74_RS09830	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC74_RS09835	COG2323	membrane
FOC74_RS09845	COG0789	Transcriptional regulator
FOC74_RS09845	COG4978	Transcriptional regulator
FOC74_RS09850	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC74_RS09855	COG0475	glutathione-regulated potassium exporter activity
FOC74_RS09865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC74_RS09870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC74_RS09875	COG3162	membrane
FOC74_RS09890	COG1280	lysine exporter protein (LysE YggA)
FOC74_RS09895	COG3403	YqcI/YcgG family
FOC74_RS09930	COG0328	RNA-DNA hybrid ribonuclease activity
FOC74_RS09950	COG0454	-acetyltransferase
FOC74_RS09965	COG0438	transferase activity, transferring glycosyl groups
FOC74_RS09970	COG1215	transferase activity, transferring glycosyl groups
FOC74_RS09985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC74_RS10010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC74_RS10025	COG0754	glutathionylspermidine amidase activity
FOC74_RS10060	COG0456	acetyltransferase
FOC74_RS10070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC74_RS10075	COG2311	Membrane
FOC74_RS10080	COG2233	PERMEase
FOC74_RS10090	COG0024	Methionine aminopeptidase
FOC74_RS10095	COG3173	Aminoglycoside phosphotransferase
FOC74_RS10105	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC74_RS10110	COG1199	ATP-dependent helicase activity
FOC74_RS10120	COG0116	Belongs to the methyltransferase superfamily
FOC74_RS10180	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC74_RS10180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC74_RS10190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC74_RS10195	COG3935	DnaD domain protein
FOC74_RS10215	COG1199	ATP-dependent helicase activity
FOC74_RS10215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC74_RS10250	COG0438	transferase activity, transferring glycosyl groups
FOC74_RS10255	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC74_RS10270	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC74_RS10275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS10285	COG2738	Putative neutral zinc metallopeptidase
FOC74_RS10300	COG4347	Protein of unknown function (DUF1405)
FOC74_RS10310	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC74_RS10330	COG0457	Tetratricopeptide repeat
FOC74_RS10335	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC74_RS10355	COG0142	geranyltranstransferase activity
FOC74_RS10365	COG0142	geranyltranstransferase activity
FOC74_RS10380	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC74_RS10455	COG0492	ferredoxin-NADP+ reductase activity
FOC74_RS10475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC74_RS10480	COG4862	establishment of competence for transformation
FOC74_RS10490	COG1408	metallophosphoesterase
FOC74_RS10500	COG1266	CAAX protease self-immunity
FOC74_RS10505	COG0514	ATP-dependent DNA helicase (RecQ)
FOC74_RS10515	COG1141	Ferredoxin
FOC74_RS10520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC74_RS10530	COG4942	peptidase
FOC74_RS10535	COG2096	Adenosyltransferase
FOC74_RS10540	COG5002	protein histidine kinase activity
FOC74_RS10545	COG0745	RESPONSE REGULATOR receiver
FOC74_RS10550	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC74_RS10555	COG1333	cytochrome c biogenesis protein
FOC74_RS10565	COG1187	pseudouridine synthase activity
FOC74_RS10570	COG0700	Nucleoside recognition
FOC74_RS10575	COG2715	membrane protein required for spore maturation
FOC74_RS10580	COG1686	Belongs to the peptidase S11 family
FOC74_RS10585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC74_RS10600	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC74_RS10600	COG0392	lysyltransferase activity
FOC74_RS10620	COG5002	protein histidine kinase activity
FOC74_RS10625	COG0582	viral genome integration into host DNA
FOC74_RS10635	COG1801	Protein of unknown function DUF72
FOC74_RS10640	COG3852	Histidine kinase
FOC74_RS10655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC74_RS10660	COG1392	Phosphate transport regulator
FOC74_RS10665	COG0306	phosphate transporter
FOC74_RS10670	COG0730	response to heat
FOC74_RS10710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC74_RS10720	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS10730	COG2197	response regulator
FOC74_RS10735	COG4585	Histidine kinase
FOC74_RS10740	COG4758	membrane
FOC74_RS10755	COG1757	Na H antiporter
FOC74_RS10775	COG0733	neurotransmitter:sodium symporter activity
FOC74_RS10780	COG1648	precorrin-2 dehydrogenase activity
FOC74_RS10800	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC74_RS10805	COG0529	Catalyzes the synthesis of activated sulfate
FOC74_RS10825	COG0019	diaminopimelate decarboxylase activity
FOC74_RS10835	COG1368	sulfuric ester hydrolase activity
FOC74_RS10840	COG1183	phosphatidylcholine synthase activity
FOC74_RS10855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC74_RS10930	COG0440	acetolactate synthase activity
FOC74_RS10935	COG0028	Belongs to the TPP enzyme family
FOC74_RS10940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC74_RS10960	COG3874	Sporulation protein YtfJ
FOC74_RS10965	COG4709	membrane
FOC74_RS10970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC74_RS10975	COG1301	dicarboxylic acid transport
FOC74_RS10985	COG1846	Transcriptional regulator
FOC74_RS11000	COG1968	undecaprenyl-diphosphatase activity
FOC74_RS11005	COG0534	Mate efflux family protein
FOC74_RS11040	COG0716	FMN binding
FOC74_RS11065	COG1696	Membrane protein involved in D-alanine export
FOC74_RS11075	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC74_RS11080	COG2070	2-Nitropropane dioxygenase
FOC74_RS11085	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC74_RS11095	COG1335	isochorismatase
FOC74_RS11105	COG1522	sequence-specific DNA binding
FOC74_RS11115	COG1266	CAAX protease self-immunity
FOC74_RS11120	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC74_RS11125	COG1131	(ABC) transporter
FOC74_RS11135	COG1131	(ABC) transporter
FOC74_RS11140	COG1725	Transcriptional regulator
FOC74_RS11145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC74_RS11165	COG1780	Probably involved in ribonucleotide reductase function
FOC74_RS11195	COG4873	Protein conserved in bacteria
FOC74_RS11210	COG0720	synthase
FOC74_RS11220	COG5002	protein histidine kinase activity
FOC74_RS11225	COG2318	DinB family
FOC74_RS11235	COG1846	Transcriptional regulator
FOC74_RS11240	COG3852	Histidine kinase
FOC74_RS11250	COG2861	carbohydrate metabolic process
FOC74_RS11260	COG0235	Class ii aldolase
FOC74_RS11270	COG1349	DNA-binding transcription factor activity
FOC74_RS11295	COG3842	ATPase activity
FOC74_RS11300	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC74_RS11315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC74_RS11325	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC74_RS11330	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS11350	COG2030	dehydratase
FOC74_RS11360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC74_RS11365	COG0861	Integral membrane protein TerC family
FOC74_RS11370	COG2116	formate transmembrane transporter activity
FOC74_RS11380	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC74_RS11400	COG2186	Transcriptional regulator
FOC74_RS11405	COG5002	protein histidine kinase activity
FOC74_RS11410	COG0745	RESPONSE REGULATOR receiver
FOC74_RS11420	COG3835	regulator
FOC74_RS11425	COG0277	FAD linked oxidase domain protein
FOC74_RS11430	COG0247	lactate metabolic process
FOC74_RS11435	COG2340	Cysteine-rich secretory protein family
FOC74_RS11445	COG0564	pseudouridine synthase activity
FOC74_RS11455	COG2409	Drug exporters of the RND superfamily
FOC74_RS11465	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC74_RS11470	COG1177	transmembrane transport
FOC74_RS11475	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC74_RS11485	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS11520	COG0681	Belongs to the peptidase S26 family
FOC74_RS11525	COG1686	Belongs to the peptidase S11 family
FOC74_RS11535	COG2226	methyltransferase
FOC74_RS11550	COG4974	Belongs to the 'phage' integrase family
FOC74_RS11570	COG4695	Portal protein
FOC74_RS11705	COG1476	TRANSCRIPTIONal
FOC74_RS11715	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC74_RS11780	COG5634	Uncharacterized conserved protein (DUF2278)
FOC74_RS11785	COG1620	l-lactate permease
FOC74_RS11820	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC74_RS11820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC74_RS11830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC74_RS11835	COG5492	domain, Protein
FOC74_RS11850	COG2382	esterase
FOC74_RS11860	COG2153	protein acetylation
FOC74_RS11905	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC74_RS11920	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC74_RS11940	COG0457	Tetratricopeptide repeat
FOC74_RS11940	COG0463	Glycosyl transferase, family 2
FOC74_RS11960	COG1216	Glycosyl transferase, family 2
FOC74_RS11960	COG0463	Glycosyl transferase, family 2
FOC74_RS11965	COG0772	Belongs to the SEDS family
FOC74_RS11980	COG0564	pseudouridine synthase activity
FOC74_RS11990	COG2357	RelA SpoT domain protein
FOC74_RS12000	COG4116	CYTH
FOC74_RS12005	COG2346	COG2346, Truncated hemoglobins
FOC74_RS12020	COG1164	Oligoendopeptidase f
FOC74_RS12030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC74_RS12035	COG4862	establishment of competence for transformation
FOC74_RS12040	COG0861	Integral membrane protein TerC family
FOC74_RS12055	COG4166	transmembrane transport
FOC74_RS12060	COG0534	Mate efflux family protein
FOC74_RS12065	COG4608	Belongs to the ABC transporter superfamily
FOC74_RS12070	COG0444	Belongs to the ABC transporter superfamily
FOC74_RS12075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC74_RS12080	COG0601	transmembrane transport
FOC74_RS12085	COG4166	transmembrane transport
FOC74_RS12095	COG0180	Tryptophanyl-tRNA synthetase
FOC74_RS12105	COG5504	Zn-dependent protease
FOC74_RS12110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC74_RS12115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS12130	COG2267	carboxylic ester hydrolase activity
FOC74_RS12140	COG0542	response to heat
FOC74_RS12150	COG0561	phosphatase activity
FOC74_RS12165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS12175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC74_RS12185	COG2996	Protein conserved in bacteria
FOC74_RS12205	COG0004	ammonium transporteR
FOC74_RS12210	COG0753	catalase activity
FOC74_RS12220	COG0367	asparagine synthase
FOC74_RS12245	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC74_RS12305	COG0398	Pfam SNARE associated Golgi protein
FOC74_RS12310	COG4903	ComK protein
FOC74_RS12335	COG2224	Isocitrate lyase
FOC74_RS12340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC74_RS12360	COG0697	spore germination
FOC74_RS12365	COG0501	Belongs to the peptidase M48B family
FOC74_RS12390	COG0745	RESPONSE REGULATOR receiver
FOC74_RS12395	COG2205	protein histidine kinase activity
FOC74_RS12410	COG2207	Transcriptional regulator
FOC74_RS12410	COG3708	Transcriptional regulator
FOC74_RS12415	COG1595	DNA-templated transcription, initiation
FOC74_RS12425	COG1078	dGTPase activity
FOC74_RS12435	COG1408	metallophosphoesterase
FOC74_RS12475	COG3209	COG3209 Rhs family protein
FOC74_RS12490	COG3209	COG3209 Rhs family protein
FOC74_RS12535	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS12545	COG0095	Lipoate-protein ligase
FOC74_RS12550	COG1234	tRNA 3'-trailer cleavage
FOC74_RS12560	COG1609	Transcriptional regulator
FOC74_RS12565	COG2378	regulation of single-species biofilm formation
FOC74_RS12575	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOC74_RS12595	COG1511	domain protein
FOC74_RS12600	COG1309	transcriptional regulator
FOC74_RS12645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC74_RS12650	COG2329	Antibiotic biosynthesis monooxygenase
FOC74_RS12655	COG3428	Bacterial PH domain
FOC74_RS12660	COG3402	PFAM membrane-flanked domain
FOC74_RS12700	COG3428	Bacterial PH domain
FOC74_RS12705	COG3402	PFAM membrane-flanked domain
FOC74_RS12715	COG1309	transcriptional regulator
FOC74_RS12770	COG4473	ABC transporter
FOC74_RS12775	COG1131	(ABC) transporter
FOC74_RS12780	COG0537	adenosine 5'-monophosphoramidase activity
FOC74_RS12785	COG4980	gas vesicle protein
FOC74_RS12805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC74_RS12810	COG3973	AAA domain
FOC74_RS12820	COG0477	Major facilitator Superfamily
FOC74_RS12825	COG0477	Major facilitator Superfamily
FOC74_RS12840	COG0772	Belongs to the SEDS family
FOC74_RS12865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC74_RS12875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC74_RS12880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC74_RS12900	COG2267	carboxylic ester hydrolase activity
FOC74_RS12910	COG0457	Tetratricopeptide repeat
FOC74_RS12915	COG0346	lactoylglutathione lyase activity
FOC74_RS12920	COG0346	lactoylglutathione lyase activity
FOC74_RS12935	COG5444	nuclease activity
FOC74_RS12955	COG4717	serine-type aminopeptidase activity
FOC74_RS12960	COG0420	3'-5' exonuclease activity
FOC74_RS13020	COG2205	protein histidine kinase activity
FOC74_RS13020	COG2198	Histidine kinase
FOC74_RS13020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC74_RS13020	COG0784	Response regulator, receiver
FOC74_RS13025	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC74_RS13030	COG2208	phosphoserine phosphatase activity
FOC74_RS13040	COG1191	sigma factor activity
FOC74_RS13065	COG3237	CsbD-like
FOC74_RS13115	COG3437	response regulator, receiver
FOC74_RS13115	COG2770	Histidine kinase
FOC74_RS13130	COG2376	Dihydroxyacetone kinase
FOC74_RS13140	COG2376	Dihydroxyacetone kinase
FOC74_RS13170	COG1183	phosphatidylcholine synthase activity
FOC74_RS13245	COG0477	Major facilitator Superfamily
FOC74_RS13265	COG0305	Participates in initiation and elongation during chromosome replication
FOC74_RS13325	COG0494	nUDIX hydrolase
FOC74_RS13330	COG3181	Tripartite tricarboxylate transporter family receptor
FOC74_RS13335	COG4565	transcriptional regulatory protein
FOC74_RS13340	COG3290	protein histidine kinase activity
FOC74_RS13345	COG0477	Major facilitator Superfamily
FOC74_RS13360	COG4608	Belongs to the ABC transporter superfamily
FOC74_RS13365	COG0444	Belongs to the ABC transporter superfamily
FOC74_RS13370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC74_RS13375	COG0601	transmembrane transport
FOC74_RS13415	COG3938	Belongs to the proline racemase family
FOC74_RS13435	COG1363	Peptidase, m42
FOC74_RS13455	COG1024	Enoyl-CoA hydratase
FOC74_RS13470	COG1696	Membrane protein involved in D-alanine export
FOC74_RS13490	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS13500	COG2244	polysaccharide biosynthetic process
FOC74_RS13505	COG0653	protein targeting
FOC74_RS13525	COG0659	secondary active sulfate transmembrane transporter activity
FOC74_RS13540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC74_RS13545	COG3409	Peptidoglycan-binding domain 1 protein
FOC74_RS13545	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS13555	COG0561	phosphatase activity
FOC74_RS13565	COG3527	Alpha-acetolactate decarboxylase
FOC74_RS13570	COG0028	Belongs to the TPP enzyme family
FOC74_RS13600	COG0189	ligase activity
FOC74_RS13615	COG1126	abc transporter atp-binding protein
FOC74_RS13620	COG0765	amino acid transport
FOC74_RS13625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC74_RS13630	COG1132	(ABC) transporter
FOC74_RS13635	COG1132	(ABC) transporter
FOC74_RS13640	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS13650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC74_RS13655	COG0531	amino acid
FOC74_RS13665	COG0753	catalase activity
FOC74_RS13665	COG0693	protein deglycase activity
FOC74_RS13670	COG0693	protein deglycase activity
FOC74_RS13680	COG2211	Major facilitator Superfamily
FOC74_RS13685	COG4533	DNA binding
FOC74_RS13695	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC74_RS13705	COG1733	regulation of RNA biosynthetic process
FOC74_RS13710	COG2814	Major facilitator Superfamily
FOC74_RS13715	COG1309	transcriptional regulator
FOC74_RS13720	COG2076	Multidrug Resistance protein
FOC74_RS13735	COG1522	sequence-specific DNA binding
FOC74_RS13755	COG2259	Doxx family
FOC74_RS13765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC74_RS13765	COG1263	PTS System
FOC74_RS13775	COG1737	Transcriptional regulator
FOC74_RS13785	COG0475	glutathione-regulated potassium exporter activity
FOC74_RS13790	COG0531	amino acid
FOC74_RS13825	COG0586	Pfam SNARE associated Golgi protein
FOC74_RS13860	COG3546	catalase activity
FOC74_RS13865	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS13880	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC74_RS13890	COG1136	(ABC) transporter
FOC74_RS13895	COG0577	efflux transmembrane transporter activity
FOC74_RS13900	COG1388	LysM domain
FOC74_RS13900	COG3584	3D domain protein
FOC74_RS13920	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC74_RS13925	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC74_RS13930	COG3711	transcriptional antiterminator
FOC74_RS13930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC74_RS13945	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC74_RS13950	COG0604	alcohol dehydrogenase
FOC74_RS13955	COG1316	TRANSCRIPTIONal
FOC74_RS13965	COG0730	response to heat
FOC74_RS13970	COG2210	Belongs to the sulfur carrier protein TusA family
FOC74_RS13980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC74_RS13985	COG0425	Belongs to the sulfur carrier protein TusA family
FOC74_RS13990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC74_RS13990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS13995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC74_RS13995	COG0425	Belongs to the sulfur carrier protein TusA family
FOC74_RS14000	COG1937	Protein conserved in bacteria
FOC74_RS14005	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC74_RS14015	COG3591	Belongs to the peptidase S1B family
FOC74_RS14025	COG2719	SpoVR family
FOC74_RS14030	COG0778	Nitroreductase
FOC74_RS14070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC74_RS14085	COG1376	ErfK ybiS ycfS ynhG family protein
FOC74_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS14095	COG2252	PERMEase
FOC74_RS14110	COG1846	Transcriptional regulator
FOC74_RS14115	COG2814	Major facilitator Superfamily
FOC74_RS14120	COG2205	protein histidine kinase activity
FOC74_RS14160	COG0351	phosphomethylpyrimidine kinase
FOC74_RS14165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC74_RS14175	COG2104	thiamine diphosphate biosynthetic process
FOC74_RS14180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC74_RS14185	COG0352	thiamine-phosphate diphosphorylase activity
FOC74_RS14190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC74_RS14195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC74_RS14200	COG1116	anion transmembrane transporter activity
FOC74_RS14205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC74_RS14225	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC74_RS14345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC74_RS14350	COG0581	inorganic phosphate transmembrane transporter activity
FOC74_RS14355	COG0573	inorganic phosphate transmembrane transporter activity
FOC74_RS14360	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC74_RS14365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC74_RS14365	COG1918	ferrous iron import across plasma membrane
FOC74_RS14370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC74_RS14375	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC74_RS14385	COG0531	amino acid
FOC74_RS14390	COG0697	spore germination
FOC74_RS14395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC74_RS14410	COG4990	cell redox homeostasis
FOC74_RS14415	COG0833	amino acid
FOC74_RS14420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC74_RS14425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC74_RS14440	COG0569	domain protein
FOC74_RS14440	COG0475	glutathione-regulated potassium exporter activity
FOC74_RS14450	COG2153	protein acetylation
FOC74_RS14465	COG2252	PERMEase
FOC74_RS14470	COG1113	amino acid transport
FOC74_RS14485	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS14490	COG3104	oligopeptide transport
FOC74_RS14505	COG1476	TRANSCRIPTIONal
FOC74_RS14510	COG3583	domain protein
FOC74_RS14510	COG3584	3D domain protein
FOC74_RS14515	COG0840	transmembrane signaling receptor activity
FOC74_RS14545	COG3568	Endonuclease Exonuclease Phosphatase
FOC74_RS14560	COG1063	alcohol dehydrogenase
FOC74_RS14580	COG1879	ABC-type sugar transport system periplasmic component
FOC74_RS14585	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC74_RS14600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC74_RS14605	COG1609	Transcriptional regulator
FOC74_RS14610	COG0477	Major facilitator Superfamily
FOC74_RS14615	COG1846	Transcriptional regulator
FOC74_RS14620	COG2271	Major facilitator Superfamily
FOC74_RS14630	COG4608	Belongs to the ABC transporter superfamily
FOC74_RS14635	COG0601	transmembrane transport
FOC74_RS14645	COG0747	negative chemotaxis
FOC74_RS14660	COG0659	secondary active sulfate transmembrane transporter activity
FOC74_RS14675	COG5002	protein histidine kinase activity
FOC74_RS14680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC74_RS14685	COG2378	regulation of single-species biofilm formation
FOC74_RS14695	COG1595	DNA-templated transcription, initiation
FOC74_RS14710	COG0833	amino acid
FOC74_RS14715	COG0765	amino acid transport
FOC74_RS14720	COG0765	amino acid transport
FOC74_RS14725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC74_RS14730	COG1126	abc transporter atp-binding protein
FOC74_RS14735	COG1115	amino acid carrier protein
FOC74_RS14740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC74_RS14750	COG0697	spore germination
FOC74_RS14765	COG0366	Alpha amylase catalytic
FOC74_RS14770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC74_RS14770	COG1263	PTS System
FOC74_RS14775	COG2188	Transcriptional regulator
FOC74_RS14780	COG0531	amino acid
FOC74_RS14800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC74_RS14805	COG0714	Associated with various cellular activities
FOC74_RS14810	COG4548	von Willebrand factor, type A
FOC74_RS14820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC74_RS14825	COG0156	8-amino-7-oxononanoate synthase activity
FOC74_RS14840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS14845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS14850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS14855	COG3104	oligopeptide transport
FOC74_RS14870	COG1620	l-lactate permease
FOC74_RS14875	COG1027	Aspartate ammonia-lyase
FOC74_RS14880	COG1253	flavin adenine dinucleotide binding
FOC74_RS14885	COG0346	lactoylglutathione lyase activity
FOC74_RS14890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS14895	COG1316	TRANSCRIPTIONal
FOC74_RS14900	COG2720	vancomycin resistance protein
FOC74_RS14920	COG3227	Zinc metalloprotease (Elastase)
FOC74_RS14935	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC74_RS14940	COG2217	Heavy metal translocating P-type atpase
FOC74_RS14945	COG0640	Transcriptional regulator
FOC74_RS14950	COG0531	amino acid
FOC74_RS14965	COG2427	Protein of unknown function (DUF1641)
FOC74_RS14970	COG3383	formate dehydrogenase (NAD+) activity
FOC74_RS14975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC74_RS14980	COG0454	-acetyltransferase
FOC74_RS14980	COG0456	acetyltransferase
FOC74_RS14985	COG0745	RESPONSE REGULATOR receiver
FOC74_RS14990	COG5002	protein histidine kinase activity
FOC74_RS15000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS15015	COG0281	malic enzyme
FOC74_RS15020	COG3493	citrate carrier protein
FOC74_RS15025	COG4565	transcriptional regulatory protein
FOC74_RS15030	COG3290	protein histidine kinase activity
FOC74_RS15040	COG4990	cell redox homeostasis
FOC74_RS15050	COG5002	protein histidine kinase activity
FOC74_RS15055	COG0745	RESPONSE REGULATOR receiver
FOC74_RS15060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC74_RS15070	COG0395	ABC-type sugar transport system, permease component
FOC74_RS15075	COG1175	transmembrane transport
FOC74_RS15080	COG3842	ATPase activity
FOC74_RS15085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC74_RS15105	COG2851	Citrate transporter
FOC74_RS15110	COG4565	transcriptional regulatory protein
FOC74_RS15115	COG3290	protein histidine kinase activity
FOC74_RS15125	COG2268	Band 7 protein
FOC74_RS15130	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC74_RS15140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC74_RS15160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC74_RS15270	COG4626	Terminase
FOC74_RS15270	COG1802	Transcriptional regulator
FOC74_RS15295	COG0582	viral genome integration into host DNA
FOC74_RS15300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC74_RS15345	COG0756	dUTP diphosphatase activity
FOC74_RS15370	COG0305	Participates in initiation and elongation during chromosome replication
FOC74_RS15405	COG1396	sequence-specific DNA binding
FOC74_RS15435	COG2766	serine protein kinase
FOC74_RS15445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC74_RS15455	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC74_RS15465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC74_RS15470	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC74_RS15585	COG0735	belongs to the Fur family
FOC74_RS15590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC74_RS15610	COG4555	ABC transporter
FOC74_RS15620	COG0069	glutamate synthase activity
FOC74_RS15620	COG0070	glutamate synthase
FOC74_RS15620	COG0067	glutamate synthase
FOC74_RS15625	COG4129	membrane
FOC74_RS15630	COG1132	(ABC) transporter
FOC74_RS15655	COG1194	a g-specific adenine glycosylase
FOC74_RS15660	COG1988	membrane-bound metal-dependent
FOC74_RS15690	COG1090	epimerase
FOC74_RS15695	COG1228	amidohydrolase
FOC74_RS15715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC74_RS15735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC74_RS15735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC74_RS15745	COG0463	Glycosyl transferase, family 2
FOC74_RS15760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC74_RS15765	COG1263	PTS System
FOC74_RS15765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC74_RS15795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC74_RS15810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC74_RS15815	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC74_RS15835	COG0535	radical SAM domain protein
FOC74_RS15845	COG0387	Pfam Sodium calcium exchanger
FOC74_RS15850	COG3871	stress protein (general stress protein 26)
FOC74_RS15865	COG0586	Pfam SNARE associated Golgi protein
FOC74_RS15890	COG0697	spore germination
FOC74_RS15895	COG2217	Heavy metal translocating P-type atpase
FOC74_RS15900	COG1295	ribonuclease BN
FOC74_RS15910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC74_RS15925	COG3853	Toxic anion resistance protein (TelA)
FOC74_RS15935	COG0861	Integral membrane protein TerC family
FOC74_RS15940	COG2310	stress, protein
FOC74_RS15945	COG2310	stress, protein
FOC74_RS15950	COG2310	stress, protein
FOC74_RS15980	COG2270	Major facilitator Superfamily
FOC74_RS16030	COG0488	(ABC) transporter
FOC74_RS16035	COG1116	anion transmembrane transporter activity
FOC74_RS16045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC74_RS16060	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC74_RS16090	COG2190	(PTS) system
FOC74_RS16090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC74_RS16090	COG1263	PTS System
FOC74_RS16095	COG0366	Alpha amylase catalytic
FOC74_RS16135	COG0840	transmembrane signaling receptor activity
FOC74_RS16145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC74_RS16150	COG0765	amino acid transport
FOC74_RS16160	COG0723	plastoquinol--plastocyanin reductase activity
FOC74_RS16160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC74_RS16165	COG2814	Major facilitator Superfamily
FOC74_RS16170	COG3541	Predicted nucleotidyltransferase
FOC74_RS16190	COG5002	protein histidine kinase activity
FOC74_RS16225	COG0166	Belongs to the GPI family
FOC74_RS16240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS16245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS16250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS16270	COG0450	alkyl hydroperoxide reductase
FOC74_RS16285	COG1473	amidohydrolase
FOC74_RS16315	COG4807	Protein conserved in bacteria
FOC74_RS16325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC74_RS16330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC74_RS16335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS16350	COG2309	aminopeptidase activity
FOC74_RS16355	COG2076	Multidrug Resistance protein
FOC74_RS16360	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS16370	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC74_RS16375	COG0546	phosphoglycolate phosphatase activity
FOC74_RS16380	COG1597	lipid kinase activity
FOC74_RS16400	COG4682	membrane
FOC74_RS16405	COG1846	Transcriptional regulator
FOC74_RS16410	COG0003	Pfam Anion-transporting ATPase
FOC74_RS16425	COG1464	Belongs to the NlpA lipoprotein family
FOC74_RS16430	COG2011	ABC-type metal ion transport system permease component
FOC74_RS16435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC74_RS16440	COG1335	isochorismatase
FOC74_RS16460	COG4851	CamS sex pheromone cAM373 precursor
FOC74_RS16470	COG0210	DNA helicase
FOC74_RS16495	COG0151	Belongs to the GarS family
FOC74_RS16505	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC74_RS16515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC74_RS16530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC74_RS16540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC74_RS16545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC74_RS16550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC74_RS16575	COG0697	spore germination
FOC74_RS16595	COG0745	RESPONSE REGULATOR receiver
FOC74_RS16600	COG2205	protein histidine kinase activity
FOC74_RS16640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC74_RS16665	COG5002	protein histidine kinase activity
FOC74_RS16675	COG2252	PERMEase
FOC74_RS16695	COG1266	CAAX protease self-immunity
FOC74_RS16710	COG0488	(ABC) transporter
FOC74_RS16720	COG0456	acetyltransferase
FOC74_RS16725	COG1214	PFAM Peptidase M22, glycoprotease
FOC74_RS16730	COG0802	atpase or kinase
FOC74_RS16825	COG2183	response to ionizing radiation
FOC74_RS16830	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC74_RS16835	COG0864	Transcriptional regulator
FOC74_RS16840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC74_RS16845	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC74_RS16855	COG0457	Tetratricopeptide repeat
FOC74_RS16855	COG0705	Rhomboid family
FOC74_RS16860	COG4294	response to UV
FOC74_RS16870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC74_RS16880	COG2814	Major facilitator Superfamily
FOC74_RS16890	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC74_RS16895	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC74_RS16925	COG0561	phosphatase activity
FOC74_RS16930	COG4608	Belongs to the ABC transporter superfamily
FOC74_RS16935	COG0444	Belongs to the ABC transporter superfamily
FOC74_RS16940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC74_RS16945	COG0601	transmembrane transport
FOC74_RS16950	COG0747	negative chemotaxis
FOC74_RS16965	COG0842	Transport permease protein
FOC74_RS16970	COG0842	Transport permease protein
FOC74_RS16970	COG1511	domain protein
FOC74_RS16975	COG1131	(ABC) transporter
FOC74_RS16980	COG2197	response regulator
FOC74_RS16985	COG4585	Histidine kinase
FOC74_RS16990	COG0488	(ABC) transporter
FOC74_RS17015	COG5298	Protein conserved in bacteria
FOC74_RS17020	COG0084	hydrolase, TatD family'
FOC74_RS17030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS17040	COG1609	Transcriptional regulator
FOC74_RS17050	COG0204	Acyl-transferase
FOC74_RS17065	COG0697	spore germination
FOC74_RS17080	COG1910	domain protein
FOC74_RS17085	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC74_RS17090	COG4149	molybdate abc transporter
FOC74_RS17105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC74_RS17110	COG0656	L-ascorbic acid biosynthetic process
FOC74_RS17115	COG4166	transmembrane transport
FOC74_RS17120	COG4166	transmembrane transport
FOC74_RS17130	COG1309	transcriptional regulator
FOC74_RS17140	COG2207	Transcriptional regulator
FOC74_RS17150	COG4166	transmembrane transport
FOC74_RS17155	COG4608	Belongs to the ABC transporter superfamily
FOC74_RS17160	COG0444	Belongs to the ABC transporter superfamily
FOC74_RS17165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC74_RS17170	COG0601	transmembrane transport
FOC74_RS17185	COG2814	Major facilitator Superfamily
FOC74_RS17195	COG2271	Major facilitator Superfamily
FOC74_RS17200	COG0277	FAD linked oxidase domain protein
FOC74_RS17210	COG0604	alcohol dehydrogenase
FOC74_RS17215	COG1464	Belongs to the NlpA lipoprotein family
FOC74_RS17220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC74_RS17225	COG2011	ABC-type metal ion transport system permease component
FOC74_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS17260	COG0823	Involved in the tonB-independent uptake of proteins
FOC74_RS17260	COG1506	peptidase
FOC74_RS17260	COG4946	Tricorn protease homolog
FOC74_RS17265	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC74_RS17285	COG0596	Alpha beta hydrolase
FOC74_RS17310	COG4856	YbbR-like protein
FOC74_RS17315	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC74_RS17395	COG0726	polysaccharide deacetylase
FOC74_RS17400	COG2194	sulfuric ester hydrolase activity
FOC74_RS17410	COG0489	protein tyrosine kinase activity
FOC74_RS17415	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS17440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC74_RS17475	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC74_RS17485	COG0024	Methionine aminopeptidase
FOC74_RS17495	COG0201	protein transport
FOC74_RS17555	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC74_RS17625	COG1358	cellular component organization or biogenesis
FOC74_RS17640	COG2813	Specifically methylates the guanine in position
FOC74_RS17660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC74_RS17665	COG0250	Participates in transcription elongation, termination and antitermination
FOC74_RS17670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC74_RS17685	COG3688	RNA-binding protein containing a PIN domain
FOC74_RS17690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC74_RS17705	COG1045	serine acetyltransferase
FOC74_RS17725	COG4956	integral membrane protein (PIN domain superfamily)
FOC74_RS17735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC74_RS17740	COG0542	response to heat
FOC74_RS17750	COG3880	PFAM UvrB UvrC protein
FOC74_RS17840	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC74_RS17845	COG1396	sequence-specific DNA binding
FOC74_RS17850	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC74_RS17855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC74_RS17860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC74_RS17865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC74_RS17870	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC74_RS17875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC74_RS17880	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC74_RS17895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC74_RS17910	COG2208	phosphoserine phosphatase activity
FOC74_RS17925	COG1098	S1 RNA binding domain
FOC74_RS17945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC74_RS17950	COG3956	TIGRFAM MazG family protein
FOC74_RS17955	COG2244	polysaccharide biosynthetic process
FOC74_RS17960	COG2002	toxin-antitoxin pair type II binding
FOC74_RS17965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC74_RS17995	COG0251	oxidation-reduction process
FOC74_RS18000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC74_RS18015	COG4466	Protein conserved in bacteria
FOC74_RS18030	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC74_RS18035	COG0084	hydrolase, TatD family'
FOC74_RS18040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC74_RS18040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC74_RS18045	COG2002	toxin-antitoxin pair type II binding
FOC74_RS18050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC74_RS18060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC74_RS18070	COG1774	PSP1 C-terminal conserved region
FOC74_RS18075	COG0470	DNA polymerase III
FOC74_RS18085	COG1982	Orn Lys Arg decarboxylase major
FOC74_RS18140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC74_RS18150	COG0590	tRNA wobble adenosine to inosine editing
FOC74_RS18155	COG1335	isochorismatase
FOC74_RS18160	COG1428	Deoxynucleoside kinase
FOC74_RS18165	COG1428	Deoxynucleoside kinase
FOC74_RS18195	COG1686	Belongs to the peptidase S11 family
FOC74_RS18200	COG0516	GMP reductase activity
FOC74_RS18200	COG0517	IMP dehydrogenase activity
FOC74_RS18235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC74_RS18240	COG0187	DNA topoisomerase II activity
FOC74_RS18250	COG2501	S4 domain
FOC74_RS18255	COG0592	DNA-directed DNA polymerase activity
FOC74_RS18265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC74_RS18275	COG0706	membrane insertase activity
FOC74_RS18280	COG1847	R3H domain protein
FOC74_RS18305	COG1192	Involved in chromosome partitioning
FOC74_RS18310	COG1475	DNA binding
FOC74_RS18320	COG0668	transmembrane transport
FOC74_RS18325	COG4481	Protein conserved in bacteria
FOC74_RS18330	COG0012	GTP binding
FOC74_RS18340	COG0629	single-stranded DNA binding
FOC74_RS18350	COG4241	membrane
FOC74_RS18355	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC74_RS18365	COG0305	Participates in initiation and elongation during chromosome replication
FOC74_RS18395	COG0745	RESPONSE REGULATOR receiver
FOC74_RS18400	COG5002	protein histidine kinase activity
FOC74_RS18405	COG4863	YycH protein
FOC74_RS18410	COG4853	Protein conserved in bacteria
FOC74_RS18415	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC74_RS18420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC74_RS18440	COG1164	Oligoendopeptidase f
FOC74_RS18465	COG1272	protein, Hemolysin III
FOC74_RS18470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC74_RS18490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC74_RS18495	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC74_RS18500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC74_RS18505	COG2814	Major facilitator Superfamily
FOC74_RS18510	COG3275	phosphorelay sensor kinase activity
FOC74_RS18515	COG3279	Response regulator of the LytR AlgR family
FOC74_RS18530	COG0628	permease
FOC74_RS18535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC74_RS18535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC74_RS18540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC74_RS18545	COG1309	transcriptional regulator
FOC74_RS18550	COG0463	Glycosyl transferase, family 2
FOC74_RS18570	COG0488	(ABC) transporter
FOC74_RS18585	COG1607	acyl-coa hydrolase
FOC74_RS18595	COG0840	transmembrane signaling receptor activity
FOC74_RS18620	COG0477	Major facilitator Superfamily
FOC74_RS18625	COG3279	Response regulator of the LytR AlgR family
FOC74_RS18630	COG1966	Carbon starvation protein
FOC74_RS18635	COG2879	small protein
FOC74_RS18640	COG3706	GGDEF domain
FOC74_RS18645	COG0351	phosphomethylpyrimidine kinase
FOC74_RS18650	COG4585	Histidine kinase
FOC74_RS18650	COG2203	Gaf domain
FOC74_RS18655	COG2197	response regulator
FOC74_RS18665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC74_RS18670	COG1011	Hydrolase
FOC74_RS18680	COG2873	o-acetylhomoserine
FOC74_RS18690	COG0460	homoserine dehydrogenase
FOC74_RS18700	COG1609	Transcriptional regulator
FOC74_RS18705	COG2755	lipolytic protein G-D-S-L family
FOC74_RS18710	COG1131	(ABC) transporter
FOC74_RS18715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC74_RS18725	COG2814	Major facilitator Superfamily
FOC74_RS18730	COG0561	phosphatase activity
FOC74_RS18735	COG2233	PERMEase
FOC74_RS18740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC74_RS18750	COG2363	Small membrane protein
FOC74_RS18760	COG3773	Cell wall hydrolase
FOC74_RS18775	COG0280	phosphate acetyltransferase
FOC74_RS18785	COG0095	Lipoate-protein ligase
FOC74_RS18805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS18810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS18815	COG1120	ATPase activity
FOC74_RS18820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS18825	COG1078	dGTPase activity
FOC74_RS18835	COG1994	Peptidase M50
FOC74_RS18845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC74_RS18850	COG0584	glycerophosphoryl diester phosphodiesterase
FOC74_RS18855	COG0789	Transcriptional regulator
FOC74_RS18860	COG2814	Major facilitator Superfamily
FOC74_RS18870	COG0010	Belongs to the arginase family
FOC74_RS18885	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC74_RS18890	COG4506	Protein conserved in bacteria
FOC74_RS18900	COG1595	DNA-templated transcription, initiation
FOC74_RS18920	COG2234	aminopeptidase activity
FOC74_RS18930	COG0024	Methionine aminopeptidase
FOC74_RS18960	COG5001	Diguanylate cyclase
FOC74_RS18960	COG3300	MHYT domain
FOC74_RS18970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC74_RS18975	COG0247	lactate metabolic process
FOC74_RS18975	COG2181	nitrate reductase activity
FOC74_RS18980	COG0183	Belongs to the thiolase family
FOC74_RS18985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC74_RS18990	COG1960	acyl-CoA dehydrogenase activity
FOC74_RS18995	COG1960	acyl-CoA dehydrogenase activity
FOC74_RS19015	COG4821	SIS domain
FOC74_RS19035	COG1494	fructose-1,6-bisphosphatase
FOC74_RS19040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC74_RS19060	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC74_RS19075	COG0009	L-threonylcarbamoyladenylate synthase
FOC74_RS19090	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC74_RS19095	COG2259	Doxx family
FOC74_RS19100	COG2190	(PTS) system
FOC74_RS19110	COG0698	ribose 5-phosphate isomerase
FOC74_RS19145	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC74_RS19195	COG3300	MHYT domain
FOC74_RS19195	COG5001	Diguanylate cyclase
FOC74_RS19210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC74_RS19230	COG0839	Belongs to the complex I subunit 6 family
FOC74_RS19240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC74_RS19245	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC74_RS19250	COG1007	ATP synthesis coupled electron transport
FOC74_RS19255	COG4836	Membrane
FOC74_RS19270	COG2385	sporulation resulting in formation of a cellular spore
FOC74_RS19275	COG3279	Response regulator of the LytR AlgR family
FOC74_RS19290	COG0739	heme binding
FOC74_RS19300	COG0726	polysaccharide deacetylase
FOC74_RS19300	COG1649	PFAM Uncharacterised BCR, COG1649
FOC74_RS19305	COG1609	Transcriptional regulator
FOC74_RS19315	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC74_RS19320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC74_RS19325	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC74_RS19325	COG0463	Glycosyl transferase, family 2
FOC74_RS19330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC74_RS19335	COG1682	transport, permease protein
FOC74_RS19340	COG1134	teichoic acid transport
FOC74_RS19345	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC74_RS19345	COG1215	transferase activity, transferring glycosyl groups
FOC74_RS19350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC74_RS19365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC74_RS19370	COG0745	RESPONSE REGULATOR receiver
FOC74_RS19375	COG5002	protein histidine kinase activity
FOC74_RS19400	COG1136	(ABC) transporter
FOC74_RS19405	COG0577	efflux transmembrane transporter activity
FOC74_RS19450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC74_RS19455	COG4715	Zinc finger, swim domain protein
FOC74_RS19480	COG3584	3D domain protein
FOC74_RS19480	COG1388	LysM domain
FOC74_RS19485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC74_RS19490	COG1215	transferase activity, transferring glycosyl groups
FOC74_RS19500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS19505	COG0791	NLP P60 protein
FOC74_RS19505	COG1388	LysM domain
FOC74_RS19515	COG1368	sulfuric ester hydrolase activity
FOC74_RS19525	COG2389	metal-binding protein
FOC74_RS19535	COG1620	l-lactate permease
FOC74_RS19565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC74_RS19570	COG1294	oxidase, subunit
FOC74_RS19575	COG1271	oxidase subunit
FOC74_RS19585	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC74_RS19590	COG0583	DNA-binding transcription factor activity
FOC74_RS19595	COG1511	domain protein
FOC74_RS19600	COG0346	lactoylglutathione lyase activity
FOC74_RS19610	COG1301	dicarboxylic acid transport
FOC74_RS19615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC74_RS19625	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC74_RS19635	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC74_RS19645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC74_RS19650	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC74_RS19655	COG1486	melibiose metabolic process
FOC74_RS19675	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC74_RS19675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC74_RS19685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC74_RS19690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC74_RS19695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC74_RS19700	COG1316	TRANSCRIPTIONal
FOC74_RS19705	COG1739	Uncharacterized protein family UPF0029
FOC74_RS19710	COG1307	EDD domain protein, DegV family
FOC74_RS19715	COG1733	regulation of RNA biosynthetic process
FOC74_RS19720	COG0791	NLP P60 protein
FOC74_RS19720	COG1388	LysM domain
FOC74_RS19725	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC74_RS19730	COG1040	competence protein
FOC74_RS19735	COG1278	Cold shock
FOC74_RS19740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC74_RS19760	COG2884	Cell division ATP-binding protein ftsE
FOC74_RS19765	COG2177	Part of the ABC transporter FtsEX involved in
FOC74_RS19770	COG0793	Belongs to the peptidase S41A family
FOC74_RS19770	COG3409	Peptidoglycan-binding domain 1 protein
FOC74_RS19775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC74_RS19780	COG1132	(ABC) transporter
FOC74_RS19795	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC74_RS19805	COG0583	DNA-binding transcription factor activity
FOC74_RS19810	COG2855	membrane
FOC74_RS19840	COG0789	Transcriptional regulator
FOC74_RS19855	COG0556	nucleotide-excision repair
FOC74_RS19860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC74_RS19870	COG1950	PFAM Membrane protein of
FOC74_RS19890	COG0110	maltose O-acetyltransferase activity
FOC74_RS19895	COG0457	Tetratricopeptide repeat
FOC74_RS19900	COG0492	ferredoxin-NADP+ reductase activity
FOC74_RS19910	COG1051	belongs to the nudix hydrolase family
FOC74_RS19920	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC74_RS19930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC74_RS19940	COG2323	membrane
FOC74_RS19955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS19980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC74_RS19995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC74_RS20030	COG1346	cytolysis
FOC74_RS20035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC74_RS20040	COG1647	Serine aminopeptidase, S33
FOC74_RS20045	COG0557	exoribonuclease II activity
FOC74_RS20105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS20135	COG3290	protein histidine kinase activity
FOC74_RS20135	COG0840	transmembrane signaling receptor activity
FOC74_RS20160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC74_RS20165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC74_RS20170	COG1252	NADH dehydrogenase
FOC74_RS20180	COG1733	regulation of RNA biosynthetic process
FOC74_RS20185	COG2814	Major facilitator Superfamily
FOC74_RS20190	COG0656	L-ascorbic acid biosynthetic process
FOC74_RS20210	COG2910	NAD(P)H-binding
FOC74_RS20215	COG1115	amino acid carrier protein
FOC74_RS20220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS20225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC74_RS20245	COG1611	Belongs to the LOG family
FOC74_RS20260	COG0783	Belongs to the Dps family
FOC74_RS20265	COG1115	amino acid carrier protein
FOC74_RS20270	COG0490	domain, Protein
FOC74_RS20275	COG0475	glutathione-regulated potassium exporter activity
FOC74_RS20290	COG1741	Belongs to the pirin family
FOC74_RS20295	COG3227	Zinc metalloprotease (Elastase)
FOC74_RS20300	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC74_RS20305	COG0840	transmembrane signaling receptor activity
FOC74_RS20330	COG5002	protein histidine kinase activity
FOC74_RS20335	COG0745	RESPONSE REGULATOR receiver
FOC74_RS20340	COG1376	ErfK ybiS ycfS ynhG family protein
FOC74_RS20350	COG0586	Pfam SNARE associated Golgi protein
FOC74_RS20385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS20395	COG0706	membrane insertase activity
FOC74_RS20405	COG0531	amino acid
FOC74_RS20410	COG2814	Major facilitator Superfamily
FOC74_RS20430	COG0840	transmembrane signaling receptor activity
FOC74_RS20435	COG0011	TIGRFAM Protein of
FOC74_RS20450	COG1686	Belongs to the peptidase S11 family
FOC74_RS20460	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC74_RS20460	COG1024	Enoyl-CoA hydratase
FOC74_RS20465	COG0183	Belongs to the thiolase family
FOC74_RS20475	COG1960	acyl-CoA dehydrogenase activity
FOC74_RS20480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS20485	COG1309	transcriptional regulator
FOC74_RS20490	COG1396	sequence-specific DNA binding
FOC74_RS20560	COG1393	Belongs to the ArsC family
FOC74_RS20570	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC74_RS20575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC74_RS20590	COG2011	ABC-type metal ion transport system permease component
FOC74_RS20595	COG1464	Belongs to the NlpA lipoprotein family
FOC74_RS20600	COG1464	Belongs to the NlpA lipoprotein family
FOC74_RS20605	COG0396	ATPase activity
FOC74_RS20610	COG0719	Fe-S assembly protein
FOC74_RS20615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC74_RS20620	COG0822	iron-sulfur transferase activity
FOC74_RS20625	COG0719	Fe-S assembly protein
FOC74_RS20630	COG0737	Belongs to the 5'-nucleotidase family
FOC74_RS20635	COG3377	Domain of unknown function (DUF1805)
FOC74_RS20645	COG0739	heme binding
FOC74_RS20670	COG4377	Putative membrane peptidase family (DUF2324)
FOC74_RS20675	COG0789	Transcriptional regulator
FOC74_RS20685	COG4470	Protein conserved in bacteria
FOC74_RS20700	COG1494	fructose-1,6-bisphosphatase
FOC74_RS20705	COG2445	Protein of unknown function DUF86
FOC74_RS20715	COG0647	UMP catabolic process
FOC74_RS20725	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC74_RS20735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC74_RS20740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC74_RS20750	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC74_RS20755	COG4837	Protein of unknown function (DUF1462)
FOC74_RS20775	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC74_RS20780	COG0390	transport system, permease component
FOC74_RS20785	COG2274	protein secretion by the type I secretion system
FOC74_RS20795	COG1252	NADH dehydrogenase
FOC74_RS20810	COG0316	Belongs to the HesB IscA family
FOC74_RS20820	COG1683	Conserved Protein
FOC74_RS20835	COG3708	Transcriptional regulator
FOC74_RS20850	COG1252	NADH dehydrogenase
FOC74_RS20870	COG3584	3D domain protein
FOC74_RS20885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC74_RS20890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC74_RS20895	COG1268	BioY protein
FOC74_RS20905	COG2050	protein possibly involved in aromatic compounds catabolism
FOC74_RS20925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC74_RS20930	COG5018	Exonuclease
FOC74_RS20950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC74_RS20960	COG2267	carboxylic ester hydrolase activity
FOC74_RS20965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC74_RS20970	COG1522	sequence-specific DNA binding
FOC74_RS20975	COG0436	Aminotransferase
FOC74_RS20980	COG1098	S1 RNA binding domain
FOC74_RS20985	COG2155	Conserved Protein
FOC74_RS21000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC74_RS21005	COG1285	pathogenesis
FOC74_RS21040	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC74_RS21135	COG1595	DNA-templated transcription, initiation
FOC74_RS21170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC74_RS21180	COG0058	SHG alpha-glucan phosphorylase activity
FOC74_RS21200	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC74_RS21205	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC74_RS21210	COG1169	isochorismate synthase
FOC74_RS21220	COG0596	Alpha beta hydrolase
FOC74_RS21225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC74_RS21235	COG4948	Mandelate Racemase Muconate Lactonizing
FOC74_RS21265	COG3964	amidohydrolase
FOC74_RS21285	COG2188	Transcriptional regulator
FOC74_RS21300	COG0577	efflux transmembrane transporter activity
FOC74_RS21305	COG1136	(ABC) transporter
FOC74_RS21310	COG0577	efflux transmembrane transporter activity
FOC74_RS21315	COG0577	efflux transmembrane transporter activity
FOC74_RS21320	COG2205	protein histidine kinase activity
FOC74_RS21325	COG0745	RESPONSE REGULATOR receiver
FOC74_RS21330	COG2207	Transcriptional regulator
FOC74_RS21330	COG3708	Transcriptional regulator
FOC74_RS21335	COG1136	(ABC) transporter
FOC74_RS21340	COG0577	efflux transmembrane transporter activity
FOC74_RS21350	COG0586	Pfam SNARE associated Golgi protein
FOC74_RS21375	COG1597	lipid kinase activity
FOC74_RS21405	COG0745	RESPONSE REGULATOR receiver
FOC74_RS21410	COG5002	protein histidine kinase activity
FOC74_RS21450	COG1842	Phage shock protein A
FOC74_RS21475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS21495	COG1294	oxidase, subunit
FOC74_RS21500	COG1271	oxidase subunit
FOC74_RS21505	COG0288	reversible hydration of carbon dioxide
FOC74_RS21540	COG0494	nUDIX hydrolase
FOC74_RS21550	COG0546	phosphoglycolate phosphatase activity
FOC74_RS21565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC74_RS21570	COG1116	anion transmembrane transporter activity
FOC74_RS21575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC74_RS21590	COG1368	sulfuric ester hydrolase activity
FOC74_RS21595	COG2267	carboxylic ester hydrolase activity
FOC74_RS21600	COG4191	Histidine kinase
FOC74_RS21605	COG5002	protein histidine kinase activity
FOC74_RS21610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC74_RS21665	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC74_RS21675	COG0438	transferase activity, transferring glycosyl groups
FOC74_RS21680	COG0671	phosphoesterase, PA-phosphatase related
FOC74_RS21685	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC74_RS21690	COG2267	carboxylic ester hydrolase activity
FOC74_RS21710	COG1794	racemase activity, acting on amino acids and derivatives
FOC74_RS21725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC74_RS21730	COG1242	4 iron, 4 sulfur cluster binding
FOC74_RS21750	COG1136	(ABC) transporter
FOC74_RS21760	COG0582	viral genome integration into host DNA
FOC74_RS21765	COG0490	domain, Protein
FOC74_RS21770	COG0475	glutathione-regulated potassium exporter activity
FOC74_RS21775	COG2814	Major facilitator Superfamily
FOC74_RS21815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC74_RS21825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC74_RS21845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC74_RS21850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC74_RS21860	COG0303	'Molybdopterin
FOC74_RS21865	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC74_RS21870	COG0314	molybdopterin synthase activity
FOC74_RS21895	COG1329	Transcriptional regulator
FOC74_RS21915	COG3832	glyoxalase III activity
FOC74_RS21925	COG2814	Major facilitator Superfamily
FOC74_RS21930	COG2081	HI0933 family
FOC74_RS21935	COG2244	polysaccharide biosynthetic process
FOC74_RS21940	COG1187	pseudouridine synthase activity
FOC74_RS21945	COG1349	DNA-binding transcription factor activity
FOC74_RS21950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC74_RS21960	COG1523	belongs to the glycosyl hydrolase 13 family
FOC74_RS21965	COG0510	thiamine kinase activity
FOC74_RS21980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS21990	COG1363	Peptidase, m42
FOC74_RS21995	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC74_RS22000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC74_RS22010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC74_RS22020	COG1674	ftsk spoiiie
FOC74_RS22035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS22060	COG2309	aminopeptidase activity
FOC74_RS22070	COG3118	belongs to the thioredoxin family
FOC74_RS22075	COG4851	CamS sex pheromone cAM373 precursor
FOC74_RS22080	COG1609	Transcriptional regulator
FOC74_RS22115	COG0666	response to abiotic stimulus
FOC74_RS22125	COG0745	RESPONSE REGULATOR receiver
FOC74_RS22135	COG2267	carboxylic ester hydrolase activity
FOC74_RS22140	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC74_RS22145	COG0517	IMP dehydrogenase activity
FOC74_RS22150	COG0454	-acetyltransferase
FOC74_RS22155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC74_RS22165	COG1595	DNA-templated transcription, initiation
FOC74_RS22195	COG0626	cystathionine gamma-synthase activity
FOC74_RS22200	COG1956	GAF domain-containing protein
FOC74_RS22205	COG1309	transcriptional regulator
FOC74_RS22210	COG0697	spore germination
FOC74_RS22215	COG0583	DNA-binding transcription factor activity
FOC74_RS22225	COG1104	cysteine desulfurase activity
FOC74_RS22240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC74_RS22250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC74_RS22265	COG3874	Sporulation protein YtfJ
FOC74_RS22270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC74_RS22275	COG0827	DNA restriction-modification system
FOC74_RS22300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS22340	COG0589	response to stress
FOC74_RS22345	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS22360	COG1476	TRANSCRIPTIONal
FOC74_RS22370	COG0662	Cupin 2, conserved barrel domain protein
FOC74_RS22415	COG0006	proline dipeptidase activity
FOC74_RS22430	COG4109	DRTGG domain
FOC74_RS22450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC74_RS22465	COG0587	DNA-directed DNA polymerase activity
FOC74_RS22470	COG0281	malic enzyme
FOC74_RS22475	COG1725	Transcriptional regulator
FOC74_RS22500	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC74_RS22505	COG0628	permease
FOC74_RS22515	COG0372	Belongs to the citrate synthase family
FOC74_RS22520	COG0538	isocitrate dehydrogenase activity
FOC74_RS22540	COG0745	RESPONSE REGULATOR receiver
FOC74_RS22545	COG5002	protein histidine kinase activity
FOC74_RS22550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC74_RS22550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC74_RS22560	COG1971	Probably functions as a manganese efflux pump
FOC74_RS22565	COG0237	dephospho-CoA kinase activity
FOC74_RS22570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC74_RS22575	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC74_RS22585	COG3611	Membrane attachment protein
FOC74_RS22590	COG1484	DNA-dependent DNA replication
FOC74_RS22600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC74_RS22625	COG1363	Peptidase, m42
FOC74_RS22630	COG1309	transcriptional regulator
FOC74_RS22635	COG1566	PFAM secretion protein HlyD family protein
FOC74_RS22640	COG2814	Major facilitator Superfamily
FOC74_RS22665	COG1418	mRNA catabolic process
FOC74_RS22675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC74_RS22720	COG1286	toxin biosynthetic process
FOC74_RS22725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC74_RS22725	COG1796	DNA polymerase
FOC74_RS22735	COG1187	pseudouridine synthase activity
FOC74_RS22740	COG1114	Component of the transport system for branched-chain amino acids
FOC74_RS22745	COG5386	Cell surface protein
FOC74_RS22755	COG5386	Cell surface protein
FOC74_RS22770	COG1120	ATPase activity
FOC74_RS22775	COG4509	Sortase family
FOC74_RS22790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC74_RS22795	COG4895	conserved protein (DUF2196)
FOC74_RS22805	COG0745	RESPONSE REGULATOR receiver
FOC74_RS22810	COG2205	protein histidine kinase activity
FOC74_RS22815	COG1131	(ABC) transporter
FOC74_RS22840	COG2318	DinB family
FOC74_RS22860	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS22865	COG1309	transcriptional regulator
FOC74_RS22870	COG1024	Enoyl-CoA hydratase
FOC74_RS22875	COG2086	electron transfer activity
FOC74_RS22880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC74_RS22885	COG3118	belongs to the thioredoxin family
FOC74_RS22895	COG1719	4-vinyl reductase, 4VR
FOC74_RS22900	COG2009	succinate dehydrogenase
FOC74_RS22905	COG1053	succinate dehydrogenase
FOC74_RS22910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC74_RS22915	COG0824	Thioesterase
FOC74_RS22920	COG1876	peptidase activity
FOC74_RS22925	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC74_RS22930	COG1360	Flagellar Motor Protein
FOC74_RS22935	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC74_RS22940	COG4152	abc transporter atp-binding protein
FOC74_RS22945	COG1668	transmembrane transport
FOC74_RS22950	COG1959	2 iron, 2 sulfur cluster binding
FOC74_RS22960	COG0697	spore germination
FOC74_RS22965	COG1396	sequence-specific DNA binding
FOC74_RS22970	COG1983	PspC domain protein
FOC74_RS22980	COG3279	Response regulator of the LytR AlgR family
FOC74_RS22985	COG3275	phosphorelay sensor kinase activity
FOC74_RS22990	COG4608	Belongs to the ABC transporter superfamily
FOC74_RS22995	COG0444	Belongs to the ABC transporter superfamily
FOC74_RS23015	COG0402	S-adenosylhomocysteine deaminase activity
FOC74_RS23020	COG0402	S-adenosylhomocysteine deaminase activity
FOC74_RS23030	COG2233	PERMEase
FOC74_RS23035	COG2197	response regulator
FOC74_RS23060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC74_RS23060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC74_RS23085	COG0798	PFAM Bile acid sodium symporter
FOC74_RS23100	COG0640	Transcriptional regulator
FOC74_RS23125	COG1595	DNA-templated transcription, initiation
FOC74_RS23130	COG2226	methyltransferase
FOC74_RS23165	COG2197	response regulator
FOC74_RS23180	COG1309	transcriptional regulator
FOC74_RS23200	COG5401	PFAM Sporulation and spore germination
FOC74_RS23215	COG0622	Phosphoesterase
FOC74_RS23265	COG0470	DNA polymerase III
FOC74_RS23265	COG1067	ATP-dependent peptidase activity
FOC74_RS23280	COG1764	response to oxidative stress
FOC74_RS23285	COG1846	Transcriptional regulator
FOC74_RS23295	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC74_RS23305	COG1587	Uroporphyrinogen-III synthase
FOC74_RS23310	COG0113	porphobilinogen synthase activity
FOC74_RS23320	COG1388	LysM domain
FOC74_RS23335	COG0285	dihydrofolate synthase activity
FOC74_RS23355	COG1077	Cell shape determining protein MreB Mrl
FOC74_RS23375	COG2894	cell division
FOC74_RS23380	COG0739	heme binding
FOC74_RS23385	COG1994	Peptidase M50
FOC74_RS23390	COG1530	ribonuclease E activity
FOC74_RS23400	COG2868	ribosomal protein
FOC74_RS23410	COG3290	protein histidine kinase activity
FOC74_RS23420	COG0745	RESPONSE REGULATOR receiver
FOC74_RS23425	COG5002	protein histidine kinase activity
FOC74_RS23430	COG1136	(ABC) transporter
FOC74_RS23435	COG0577	efflux transmembrane transporter activity
FOC74_RS23440	COG0577	efflux transmembrane transporter activity
FOC74_RS23445	COG0077	Prephenate dehydratase
FOC74_RS23450	COG2258	MOSC domain
FOC74_RS23455	COG1827	regulation of RNA biosynthetic process
FOC74_RS23460	COG1104	cysteine desulfurase activity
FOC74_RS23465	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC74_RS23470	COG0157	Belongs to the NadC ModD family
FOC74_RS23500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC74_RS23530	COG1862	Preprotein translocase
FOC74_RS23540	COG2323	membrane
FOC74_RS23545	COG2244	polysaccharide biosynthetic process
FOC74_RS23555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC74_RS23555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC74_RS23560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC74_RS23565	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC74_RS23565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC74_RS23575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC74_RS23605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC74_RS23615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC74_RS23620	COG1959	2 iron, 2 sulfur cluster binding
FOC74_RS23625	COG1104	cysteine desulfurase activity
FOC74_RS23640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC74_RS23660	COG0628	permease
FOC74_RS23690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC74_RS23695	COG4122	O-methyltransferase activity
FOC74_RS23720	COG0768	penicillin binding
FOC74_RS23745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC74_RS23750	COG0626	cystathionine gamma-synthase activity
FOC74_RS23755	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS23755	COG1454	alcohol dehydrogenase
FOC74_RS23765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS23805	COG2259	Doxx family
FOC74_RS23810	COG2514	catechol 2,3-dioxygenase activity
FOC74_RS23820	COG3186	Phenylalanine-4-hydroxylase
FOC74_RS23825	COG1404	Belongs to the peptidase S8 family
FOC74_RS23860	COG2267	carboxylic ester hydrolase activity
FOC74_RS23870	COG1785	Belongs to the alkaline phosphatase family
FOC74_RS23880	COG2357	RelA SpoT domain protein
FOC74_RS23885	COG0778	Nitroreductase
FOC74_RS23895	COG1595	DNA-templated transcription, initiation
FOC74_RS23920	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC74_RS23925	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC74_RS23935	COG1534	Rna-binding protein
FOC74_RS23945	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC74_RS23950	COG0799	negative regulation of ribosome biogenesis
FOC74_RS23955	COG2226	methyltransferase
FOC74_RS23960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC74_RS23965	COG1596	polysaccharide export
FOC74_RS23965	COG1555	photosystem II stabilization
FOC74_RS23970	COG2131	deaminase
FOC74_RS23975	COG2333	competence protein COMEC
FOC74_RS23975	COG0658	competence protein
FOC74_RS23985	COG1466	dna polymerase III delta subunit
FOC74_RS24010	COG1733	regulation of RNA biosynthetic process
FOC74_RS24015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC74_RS24045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC74_RS24050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC74_RS24055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC74_RS24060	COG1610	YqeY-like protein
FOC74_RS24075	COG1702	phosphate starvation-inducible protein PhoH
FOC74_RS24080	COG1480	7TM receptor with intracellular HD hydrolase
FOC74_RS24090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC74_RS24095	COG0295	cytidine deaminase activity
FOC74_RS24100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC74_RS24115	COG0517	IMP dehydrogenase activity
FOC74_RS24130	COG0358	DNA primase activity
FOC74_RS24135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC74_RS24140	COG2010	Cytochrome c
FOC74_RS24145	COG2384	SAM-dependent methyltransferase
FOC74_RS24150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC74_RS24180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS24185	COG1121	(ABC) transporter
FOC74_RS24190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC74_RS24195	COG0735	belongs to the Fur family
FOC74_RS24220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC74_RS24225	COG0477	Major facilitator Superfamily
FOC74_RS24235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC74_RS24240	COG0573	inorganic phosphate transmembrane transporter activity
FOC74_RS24245	COG0581	inorganic phosphate transmembrane transporter activity
FOC74_RS24255	COG0704	Plays a role in the regulation of phosphate uptake
FOC74_RS24260	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC74_RS24265	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC74_RS24270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC74_RS24275	COG4483	Protein conserved in bacteria
FOC74_RS24280	COG1940	carbohydrate kinase activity
FOC74_RS24290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS24310	COG0626	cystathionine gamma-synthase activity
FOC74_RS24315	COG0626	cystathionine gamma-synthase activity
FOC74_RS24320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC74_RS24320	COG0646	methionine synthase
FOC74_RS24325	COG0646	methionine synthase
FOC74_RS24325	COG1410	methionine synthase
FOC74_RS24330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC74_RS24375	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC74_RS24490	COG1459	type II secretion system
FOC74_RS24500	COG4970	Tfp pilus assembly protein FimT
FOC74_RS24555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC74_RS24585	COG1725	Transcriptional regulator
FOC74_RS24590	COG1131	(ABC) transporter
FOC74_RS24625	COG2076	Multidrug Resistance protein
FOC74_RS24630	COG2076	Multidrug Resistance protein
FOC74_RS24640	COG1609	Transcriptional regulator
FOC74_RS24645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC74_RS24650	COG0095	Lipoate-protein ligase
FOC74_RS24670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC74_RS24680	COG3872	metal-dependent enzyme
FOC74_RS24695	COG0006	proline dipeptidase activity
FOC74_RS24720	COG3854	ATPases associated with a variety of cellular activities
FOC74_RS24765	COG0511	ligase activity, forming carbon-carbon bonds
FOC74_RS24770	COG0439	Biotin carboxylase
FOC74_RS24775	COG1302	Protein conserved in bacteria
FOC74_RS24800	COG0142	geranyltranstransferase activity
FOC74_RS24810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC74_RS24820	COG0497	DNA recombination
FOC74_RS24825	COG0750	zinc metalloprotease
FOC74_RS24830	COG0745	RESPONSE REGULATOR receiver
FOC74_RS24840	COG3093	addiction module antidote protein HigA
FOC74_RS24845	COG0584	glycerophosphoryl diester phosphodiesterase
FOC74_RS24855	COG3290	protein histidine kinase activity
FOC74_RS24855	COG3829	transcription factor binding
FOC74_RS24860	COG0280	phosphate acetyltransferase
FOC74_RS24875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC74_RS24880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC74_RS24885	COG0022	dehydrogenase e1 component
FOC74_RS24890	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC74_RS24895	COG0772	Belongs to the SEDS family
FOC74_RS24900	COG2816	NAD+ diphosphatase activity
FOC74_RS24915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC74_RS24920	COG0765	amino acid transport
FOC74_RS24925	COG1126	abc transporter atp-binding protein
FOC74_RS24930	COG4129	membrane
FOC74_RS24935	COG1376	ErfK ybiS ycfS ynhG family protein
FOC74_RS24950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC74_RS24955	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC74_RS24965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC74_RS24985	COG1760	l-serine dehydratase
FOC74_RS24990	COG1760	l-serine dehydratase
FOC74_RS24995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC74_RS25000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS25005	COG0300	oxidoreductase activity
FOC74_RS25020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC74_RS25030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC74_RS25050	COG1522	sequence-specific DNA binding
FOC74_RS25060	COG0737	Belongs to the 5'-nucleotidase family
FOC74_RS25075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC74_RS25090	COG1073	alpha beta
FOC74_RS25090	COG2226	methyltransferase
FOC74_RS25095	COG4106	trans-aconitate 2-methyltransferase activity
FOC74_RS25120	COG0307	riboflavin synthase, alpha
FOC74_RS25125	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC74_RS25125	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC74_RS25140	COG1073	alpha beta
FOC74_RS25145	COG0456	acetyltransferase
FOC74_RS25150	COG1609	Transcriptional regulator
FOC74_RS25155	COG2056	Na+-H+ antiporter family
FOC74_RS25160	COG0596	Alpha beta hydrolase
FOC74_RS25170	COG4085	toxin activity
FOC74_RS25170	COG0737	Belongs to the 5'-nucleotidase family
FOC74_RS25170	COG1525	nuclease
FOC74_RS25180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC74_RS25180	COG0456	acetyltransferase
FOC74_RS25185	COG0656	L-ascorbic acid biosynthetic process
FOC74_RS25190	COG0667	Aldo Keto reductase
FOC74_RS25210	COG1300	Membrane
FOC74_RS25215	COG0735	belongs to the Fur family
FOC74_RS25225	COG4974	Belongs to the 'phage' integrase family
FOC74_RS25250	COG0598	Magnesium transport protein CorA
FOC74_RS25265	COG1846	Transcriptional regulator
FOC74_RS25280	COG1131	(ABC) transporter
FOC74_RS25285	COG1725	Transcriptional regulator
FOC74_RS25290	COG1686	Belongs to the peptidase S11 family
FOC74_RS25310	COG0733	neurotransmitter:sodium symporter activity
FOC74_RS25335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC74_RS25350	COG0697	spore germination
FOC74_RS25355	COG0561	phosphatase activity
FOC74_RS25360	COG4086	secreted protein
FOC74_RS25365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC74_RS25370	COG0456	acetyltransferase
FOC74_RS25375	COG1547	Domain of unknown function (DUF309)
FOC74_RS25400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC74_RS25410	COG2188	Transcriptional regulator
FOC74_RS25420	COG3711	transcriptional antiterminator
FOC74_RS25425	COG2190	(PTS) system
FOC74_RS25425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC74_RS25425	COG1263	PTS System
FOC74_RS25450	COG0778	Nitroreductase
FOC74_RS25455	COG3706	GGDEF domain
FOC74_RS25460	COG2084	Dehydrogenase
FOC74_RS25495	COG0436	Aminotransferase
FOC74_RS25500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC74_RS25520	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS25525	COG1695	Transcriptional regulator
FOC74_RS25560	COG0183	Belongs to the thiolase family
FOC74_RS25600	COG3842	ATPase activity
FOC74_RS25605	COG0366	Alpha amylase catalytic
FOC74_RS25615	COG2182	Extracellular solute-binding protein
FOC74_RS25620	COG1175	transmembrane transport
FOC74_RS25625	COG3833	ABC-type maltose transport systems, permease component
FOC74_RS25630	COG1609	Transcriptional regulator
FOC74_RS25635	COG0436	Aminotransferase
FOC74_RS25645	COG2205	protein histidine kinase activity
FOC74_RS25655	COG3209	COG3209 Rhs family protein
FOC74_RS25675	COG2814	Major facilitator Superfamily
FOC74_RS25710	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC74_RS25720	COG1408	metallophosphoesterase
FOC74_RS25725	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS25730	COG2200	EAL domain
FOC74_RS25745	COG4703	Protein of unknown function (DUF1797)
FOC74_RS25755	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC74_RS25765	COG0517	IMP dehydrogenase activity
FOC74_RS25770	COG0583	DNA-binding transcription factor activity
FOC74_RS25790	COG0569	domain protein
FOC74_RS25795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC74_RS25805	COG0561	phosphatase activity
FOC74_RS25810	COG0242	peptide deformylase activity
FOC74_RS25820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC74_RS25825	COG0022	dehydrogenase e1 component
FOC74_RS25875	COG1982	Orn Lys Arg decarboxylase major
FOC74_RS25895	COG0483	inositol monophosphate 1-phosphatase activity
FOC74_RS25920	COG4896	Protein conserved in bacteria
FOC74_RS25930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC74_RS25935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC74_RS25945	COG0772	Belongs to the SEDS family
FOC74_RS25950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC74_RS25985	COG3336	cytochrome c oxidase
FOC74_RS25995	COG3344	reverse transcriptase
FOC74_RS26010	COG2340	Cysteine-rich secretory protein family
FOC74_RS26025	COG0406	alpha-ribazole phosphatase activity
FOC74_RS26030	COG3679	Belongs to the UPF0342 family
FOC74_RS26045	COG0742	ribosomal rna small subunit methyltransferase
FOC74_RS26055	COG3314	Sporulation integral membrane protein YlbJ
FOC74_RS26060	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC74_RS26065	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC74_RS26075	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC74_RS26080	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC74_RS26095	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC74_RS26110	COG4839	cell division protein FtsL
FOC74_RS26120	COG0768	penicillin binding
FOC74_RS26125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC74_RS26140	COG0772	Belongs to the SEDS family
FOC74_RS26150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC74_RS26155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC74_RS26160	COG0849	cell division
FOC74_RS26165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC74_RS26175	COG1191	sigma factor activity
FOC74_RS26180	COG1191	sigma factor activity
FOC74_RS26185	COG1873	PFAM PRC-barrel domain
FOC74_RS26195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC74_RS26205	COG0762	integral membrane protein
FOC74_RS26210	COG2302	S4 RNA-binding domain
FOC74_RS26215	COG3599	regulation of cell shape
FOC74_RS26235	COG0564	pseudouridine synthase activity
FOC74_RS26300	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC74_RS26315	COG0006	proline dipeptidase activity
FOC74_RS26325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC74_RS26330	COG1561	YicC-like family, N-terminal region
FOC74_RS26350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC74_RS26355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC74_RS26360	COG0242	peptide deformylase activity
FOC74_RS26370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC74_RS26370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC74_RS26380	COG0631	protein serine/threonine phosphatase activity
FOC74_RS26385	COG0515	serine threonine protein kinase
FOC74_RS26385	COG2815	serine threonine protein kinase
FOC74_RS26390	COG1162	GTPase activity
FOC74_RS26395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC74_RS26400	COG1564	THIamine pyrophosphokinase
FOC74_RS26415	COG1302	Protein conserved in bacteria
FOC74_RS26420	COG1461	Dihydroxyacetone kinase
FOC74_RS26425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC74_RS26440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC74_RS26445	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS26450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC74_RS26460	COG1196	nuclear chromosome segregation
FOC74_RS26465	COG0552	protein localization to endoplasmic reticulum
FOC74_RS26475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC74_RS26485	COG1837	Belongs to the UPF0109 family
FOC74_RS26525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC74_RS26530	COG0758	DNA mediated transformation
FOC74_RS26535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC74_RS26545	COG4974	Belongs to the 'phage' integrase family
FOC74_RS26575	COG0528	UMP kinase activity
FOC74_RS26590	COG4589	Belongs to the CDS family
FOC74_RS26600	COG0750	zinc metalloprotease
FOC74_RS26620	COG0195	Participates in both transcription termination and antitermination
FOC74_RS26625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC74_RS26630	COG1358	cellular component organization or biogenesis
FOC74_RS26640	COG1550	Protein conserved in bacteria
FOC74_RS26650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC74_RS26655	COG0196	riboflavin kinase activity
FOC74_RS26670	COG0726	polysaccharide deacetylase
FOC74_RS26675	COG0612	Peptidase, M16
FOC74_RS26680	COG1873	PFAM PRC-barrel domain
FOC74_RS26685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC74_RS26690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC74_RS26695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC74_RS26700	COG0527	aspartate kinase activity
FOC74_RS26710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC74_RS26715	COG0740	serine-type endopeptidase activity
FOC74_RS26725	COG1674	ftsk spoiiie
FOC74_RS26730	COG2188	Transcriptional regulator
FOC74_RS26755	COG0612	Peptidase, M16
FOC74_RS26760	COG0612	Peptidase, M16
FOC74_RS26765	COG0300	oxidoreductase activity
FOC74_RS26780	COG1426	Protein conserved in bacteria
FOC74_RS26785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC74_RS26810	COG1692	metallophosphoesterase
FOC74_RS26815	COG2359	stage V sporulation protein S
FOC74_RS26825	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC74_RS26825	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC74_RS26830	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC74_RS26840	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC74_RS26860	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC74_RS26870	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC74_RS26875	COG1368	sulfuric ester hydrolase activity
FOC74_RS26880	COG0562	UDP-galactopyranose mutase
FOC74_RS26885	COG3773	Cell wall hydrolase
FOC74_RS26890	COG1404	Belongs to the peptidase S8 family
FOC74_RS26910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC74_RS26915	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC74_RS26915	COG0596	Alpha beta hydrolase
FOC74_RS26920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC74_RS26925	COG1380	Effector of murein hydrolase LrgA
FOC74_RS26930	COG1346	cytolysis
FOC74_RS26945	COG3300	MHYT domain
FOC74_RS26945	COG5001	Diguanylate cyclase
FOC74_RS26950	COG0346	lactoylglutathione lyase activity
FOC74_RS26955	COG2267	carboxylic ester hydrolase activity
FOC74_RS26970	COG2364	Membrane
FOC74_RS26980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC74_RS26985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC74_RS26990	COG2169	Transcriptional regulator
FOC74_RS26995	COG0708	Exodeoxyribonuclease III
FOC74_RS27000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS27005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS27010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS27015	COG1120	ATPase activity
FOC74_RS27020	COG2819	hydrolase of the alpha beta superfamily
FOC74_RS27030	COG1937	Protein conserved in bacteria
FOC74_RS27035	COG2608	mercury ion transmembrane transporter activity
FOC74_RS27040	COG2217	Heavy metal translocating P-type atpase
FOC74_RS27055	COG2116	formate transmembrane transporter activity
FOC74_RS27060	COG1408	metallophosphoesterase
FOC74_RS27075	COG1113	amino acid transport
FOC74_RS27085	COG2322	membrane
FOC74_RS27090	COG1979	alcohol dehydrogenase
FOC74_RS27095	COG1349	DNA-binding transcription factor activity
FOC74_RS27100	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC74_RS27105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC74_RS27105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC74_RS27105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC74_RS27110	COG3584	3D domain protein
FOC74_RS27110	COG1388	LysM domain
FOC74_RS27140	COG0464	growth
FOC74_RS27145	COG2860	membrane
FOC74_RS27150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC74_RS27155	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC74_RS27160	COG0789	Transcriptional regulator
FOC74_RS27165	COG0174	glutamine synthetase
FOC74_RS27180	COG5444	nuclease activity
FOC74_RS27195	COG1695	Transcriptional regulator
FOC74_RS27215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC74_RS27225	COG0737	Belongs to the 5'-nucleotidase family
FOC74_RS27235	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC74_RS27240	COG3639	organic phosphonate transmembrane transporter activity
FOC74_RS27270	COG1132	(ABC) transporter
FOC74_RS27275	COG1132	(ABC) transporter
FOC74_RS27290	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC74_RS27290	COG3409	Peptidoglycan-binding domain 1 protein
FOC74_RS27300	COG0730	response to heat
FOC74_RS27315	COG1346	cytolysis
FOC74_RS27325	COG0583	DNA-binding transcription factor activity
FOC74_RS27335	COG1131	(ABC) transporter
FOC74_RS27345	COG1473	amidohydrolase
FOC74_RS27355	COG0785	Cytochrome C biogenesis protein
FOC74_RS27360	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC74_RS27420	COG0010	Belongs to the arginase family
FOC74_RS27425	COG1329	Transcriptional regulator
FOC74_RS27430	COG1902	pentaerythritol trinitrate reductase activity
FOC74_RS27435	COG0069	glutamate synthase activity
FOC74_RS27440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC74_RS27445	COG0346	lactoylglutathione lyase activity
FOC74_RS27450	COG0400	carboxylic ester hydrolase activity
FOC74_RS27455	COG5002	protein histidine kinase activity
FOC74_RS27465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC74_RS27520	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS27525	COG1268	BioY protein
FOC74_RS27530	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS27535	COG0183	Belongs to the thiolase family
FOC74_RS27550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC74_RS27590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC74_RS27595	COG2274	protein secretion by the type I secretion system
FOC74_RS27605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC74_RS27635	COG0824	Thioesterase
FOC74_RS27640	COG4841	protein insertion into membrane
FOC74_RS27660	COG0745	RESPONSE REGULATOR receiver
FOC74_RS27665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC74_RS27670	COG1832	CoA-binding protein
FOC74_RS27675	COG0187	DNA topoisomerase II activity
FOC74_RS27680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC74_RS27685	COG0673	inositol 2-dehydrogenase activity
FOC74_RS27695	COG1131	(ABC) transporter
FOC74_RS27715	COG1595	DNA-templated transcription, initiation
FOC74_RS27725	COG1316	TRANSCRIPTIONal
FOC74_RS27730	COG1301	dicarboxylic acid transport
FOC74_RS27735	COG4166	transmembrane transport
FOC74_RS27740	COG4166	transmembrane transport
FOC74_RS27750	COG4166	transmembrane transport
FOC74_RS27755	COG2226	methyltransferase
FOC74_RS27795	COG0697	spore germination
FOC74_RS27800	COG3383	formate dehydrogenase (NAD+) activity
FOC74_RS27805	COG2427	Protein of unknown function (DUF1641)
FOC74_RS27810	COG5609	conserved protein (DUF2294)
FOC74_RS27815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC74_RS27825	COG2116	formate transmembrane transporter activity
FOC74_RS27830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC74_RS27835	COG0303	'Molybdopterin
FOC74_RS27840	COG0314	molybdopterin synthase activity
FOC74_RS27850	COG0489	protein tyrosine kinase activity
FOC74_RS27870	COG2962	Rard protein
FOC74_RS27875	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC74_RS27880	COG1657	PFAM Prenyltransferase squalene oxidase
FOC74_RS27890	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS27895	COG1012	belongs to the aldehyde dehydrogenase family
FOC74_RS27905	COG4145	pantothenate transmembrane transporter activity
FOC74_RS27920	COG0165	Argininosuccinate lyase
FOC74_RS27930	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS27950	COG1051	belongs to the nudix hydrolase family
FOC74_RS27960	COG0716	FMN binding
FOC74_RS28000	COG2720	vancomycin resistance protein
FOC74_RS28005	COG2514	catechol 2,3-dioxygenase activity
FOC74_RS28020	COG1285	pathogenesis
FOC74_RS28030	COG1024	Enoyl-CoA hydratase
FOC74_RS28035	COG1216	Glycosyl transferase, family 2
FOC74_RS28075	COG0385	Bile acid
FOC74_RS28085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC74_RS28090	COG2808	Putative FMN-binding domain
FOC74_RS28100	COG0457	Tetratricopeptide repeat
FOC74_RS28110	COG0604	alcohol dehydrogenase
FOC74_RS28115	COG0640	Transcriptional regulator
FOC74_RS28140	COG0584	glycerophosphoryl diester phosphodiesterase
FOC74_RS28170	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC74_RS28175	COG1164	Oligoendopeptidase f
FOC74_RS28180	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOC74_RS28195	COG1193	negative regulation of DNA recombination
FOC74_RS28215	COG0583	DNA-binding transcription factor activity
FOC74_RS28250	COG0384	phenazine biosynthesis protein PhzF
FOC74_RS28255	COG3739	integral membrane protein
FOC74_RS28260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS28265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC74_RS28270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC74_RS28285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC74_RS28290	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC74_RS28320	COG2814	Major facilitator Superfamily
FOC74_RS28325	COG1113	amino acid transport
FOC74_RS28330	COG0604	alcohol dehydrogenase
FOC74_RS28365	COG2072	flavoprotein involved in K transport
FOC74_RS28405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS28415	COG1151	hydroxylamine reductase activity
FOC74_RS28440	COG3152	Membrane
FOC74_RS28460	COG1309	transcriptional regulator
FOC74_RS28475	COG1191	sigma factor activity
FOC74_RS28495	COG1733	regulation of RNA biosynthetic process
FOC74_RS28500	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC74_RS28505	COG0318	PFAM AMP-dependent synthetase and ligase
FOC74_RS28530	COG0384	phenazine biosynthesis protein PhzF
FOC74_RS28550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC74_RS28565	COG1733	regulation of RNA biosynthetic process
FOC74_RS28570	COG1733	regulation of RNA biosynthetic process
FOC74_RS28575	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC74_RS28580	COG0673	inositol 2-dehydrogenase activity
FOC74_RS28585	COG2188	Transcriptional regulator
FOC74_RS28595	COG1393	Belongs to the ArsC family
FOC74_RS28625	COG0814	amino acid
FOC74_RS28665	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS28685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC74_RS28700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC74_RS28710	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC74_RS28715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC74_RS28725	COG1070	Carbohydrate kinase
FOC74_RS28730	COG2706	6-phosphogluconolactonase activity
FOC74_RS28735	COG3813	Protein conserved in bacteria
FOC74_RS28740	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC74_RS28745	COG0697	spore germination
FOC74_RS28750	COG0789	Transcriptional regulator
FOC74_RS28755	COG1253	flavin adenine dinucleotide binding
FOC74_RS28785	COG0477	Major facilitator Superfamily
FOC74_RS28795	COG2226	methyltransferase
FOC74_RS28815	COG0628	permease
FOC74_RS28835	COG1136	(ABC) transporter
FOC74_RS28835	COG0577	efflux transmembrane transporter activity
FOC74_RS28845	COG0110	maltose O-acetyltransferase activity
FOC74_RS28850	COG0738	Major facilitator superfamily
FOC74_RS28855	COG1940	carbohydrate kinase activity
FOC74_RS28860	COG0346	lactoylglutathione lyase activity
FOC74_RS28895	COG1011	Hydrolase
FOC74_RS28920	COG1131	(ABC) transporter
FOC74_RS28930	COG1028	Short-chain dehydrogenase reductase Sdr
FOC74_RS28950	COG0778	Nitroreductase
FOC74_RS28955	COG1733	regulation of RNA biosynthetic process
FOC74_RS28975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC74_RS28980	COG3344	reverse transcriptase
FOC74_RS28985	COG1051	belongs to the nudix hydrolase family
FOC74_RS28990	COG0537	adenosine 5'-monophosphoramidase activity
FOC74_RS28995	COG3344	reverse transcriptase
FOC74_RS29010	COG1309	transcriptional regulator
FOC74_RS29015	COG2814	Major facilitator Superfamily
FOC74_RS29030	COG1288	antiporter activity
FOC74_RS29035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC74_RS29050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC74_RS29085	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC74_RS29095	COG2031	fatty acid transporter
FOC74_RS29105	COG1309	transcriptional regulator
FOC74_RS29110	COG2076	Multidrug Resistance protein
FOC74_RS29125	COG2814	Major facilitator Superfamily
FOC74_RS29130	COG1846	Transcriptional regulator
FOC74_RS29140	COG0477	Major facilitator Superfamily