locus-tag class description FOC75_RS00035 ENOG41060SN FOC75_RS00065 ENOG4106CGH Phage Mu protein F like protein FOC75_RS00070 ENOG4108MDF Phage Portal Protein FOC75_RS00110 ENOG4105QBX endodeoxyribonuclease RusA FOC75_RS00210 ENOG4105CDU Replicative dna helicase FOC75_RS00230 ENOG4108PNI recT protein FOC75_RS00235 ENOG4108NF7 phage-type endonuclease FOC75_RS00295 ENOG4107QJE Chromosome Partitioning Protein FOC75_RS00335 ENOG4105PKS Excinuclease abc c subunit domain protein FOC75_RS00350 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC75_RS00395 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC75_RS00400 ENOG4105ECP epimerase FOC75_RS00430 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC75_RS00435 ENOG4105CEN a g-specific adenine glycosylase FOC75_RS00440 ENOG4106BXE FOC75_RS00460 ENOG4105BZ1 (ABC) transporter FOC75_RS00465 ENOG4107NBY Membrane FOC75_RS00470 ENOG4105CBC glutamate synthase FOC75_RS00480 ENOG4108IUW ABC transporter FOC75_RS00500 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC75_RS00505 ENOG4105G5W regulator Fur family FOC75_RS00620 ENOG4108JQC penicillin-binding protein 1A FOC75_RS00625 ENOG4107ZQN disulfide bond FOC75_RS00635 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC75_RS00645 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC75_RS00650 ENOG4105BZU Histidine kinase FOC75_RS00655 ENOG4105CYN Serine protein kinase FOC75_RS00685 ENOG4108IMY Transcriptional regulator FOC75_RS00720 ENOG4105CDU Replicative dna helicase FOC75_RS00745 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) FOC75_RS00790 ENOG410682Q Phage transcriptional regulator, ArpU FOC75_RS00820 ENOG4105CAR Terminase, large subunit FOC75_RS00920 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOC75_RS00950 ENOG4105C94 Transporter FOC75_RS00965 ENOG4105DZ6 Band 7 protein FOC75_RS00975 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC75_RS00980 ENOG4108V9W transcriptional regulatory protein FOC75_RS00985 ENOG4105D4T Citrate transporter FOC75_RS01005 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC75_RS01010 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC75_RS01015 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FOC75_RS01020 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOC75_RS01025 ENOG4105BZ7 extracellular solute-binding protein family 1 FOC75_RS01030 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOC75_RS01035 ENOG4108STX response regulator FOC75_RS01040 ENOG4105US7 Histidine kinase FOC75_RS01065 ENOG4108MRH transcriptional regulatory protein FOC75_RS01075 ENOG4105C6K Malic enzyme FOC75_RS01085 ENOG4108UZ3 Transporter FOC75_RS01090 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS01100 ENOG4105BZU Histidine kinase FOC75_RS01105 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS01110 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC75_RS01115 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC75_RS01120 ENOG4108JB9 formate dehydrogenase FOC75_RS01140 ENOG4105CUB amino acid FOC75_RS01150 ENOG4105C59 p-type ATPase FOC75_RS01155 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC75_RS01190 ENOG41073R8 VanW family FOC75_RS01195 ENOG4108KGH TRANSCRIPTIONal FOC75_RS01200 ENOG4105D9N nucleoside FOC75_RS01205 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC75_RS01210 ENOG4105C37 (CBS) domain FOC75_RS01215 ENOG4108IJ0 Aspartate ammonia-lyase FOC75_RS01220 ENOG4105DAA L-lactate FOC75_RS01235 ENOG4105DUX Transporter FOC75_RS01240 ENOG4108MES Periplasmic binding protein FOC75_RS01245 ENOG4105DQ5 transport system permease protein FOC75_RS01250 ENOG4108IHU transport system permease protein FOC75_RS01255 ENOG4105E0A ABC, transporter FOC75_RS01270 ENOG4105EXW epimerase dehydratase FOC75_RS01280 ENOG4107T89 von Willebrand factor, type A FOC75_RS01285 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC75_RS01290 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC75_RS01305 ENOG4105BZU Histidine kinase FOC75_RS01310 ENOG4105D5Q Arginine ornithine antiporter FOC75_RS01315 ENOG4107414 GntR family transcriptional regulator FOC75_RS01320 ENOG4105C5Y PTS System FOC75_RS01325 ENOG4105CG3 alpha amylase, catalytic region FOC75_RS01340 ENOG4105E1K spore germination protein FOC75_RS01350 ENOG4105CRN Aminoglycoside phosphotransferase FOC75_RS01355 ENOG4105BZG amino acid carrier protein FOC75_RS01360 ENOG4105CDA abc transporter atp-binding protein FOC75_RS01365 ENOG4105CT1 (ABC) transporter FOC75_RS01370 ENOG4105EAD ABC transporter FOC75_RS01375 ENOG4105DRP amino acid AbC transporter FOC75_RS01380 ENOG4108IQI permease FOC75_RS01395 ENOG4105GFR rna polymerase sigma factor FOC75_RS01405 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC75_RS01410 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC75_RS01415 ENOG4105BZU Histidine kinase FOC75_RS01420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS01430 ENOG4105CHH sulfate transporter FOC75_RS01435 ENOG41068KF Universal stress protein FOC75_RS01445 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC75_RS01455 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC75_RS01460 ENOG4108JQ7 (ABC) transporter FOC75_RS01470 ENOG4105CXY transporter FOC75_RS01475 ENOG41067TZ transcriptional regulator, MarR family FOC75_RS01480 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC75_RS01485 ENOG4105ETE Transcriptional regulator (LacI family FOC75_RS01490 ENOG4108RVA ribokinase FOC75_RS01505 ENOG4105CNN ABC, transporter FOC75_RS01510 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC75_RS01575 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC75_RS01580 ENOG41069ER domain protein FOC75_RS01585 ENOG4105VZ8 Transcriptional regulator FOC75_RS01590 ENOG4107D63 FOC75_RS01600 ENOG4105DUX Transporter FOC75_RS01620 ENOG4105C85 amino acid FOC75_RS01625 ENOG4105C7N Xanthine uracil vitamin C permease FOC75_RS01640 ENOG4105MA6 gCN5-related N-acetyltransferase FOC75_RS01665 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC75_RS01670 ENOG4105E2S oxidase) subunit II FOC75_RS01675 ENOG4108IQI permease FOC75_RS01690 ENOG4106CAD Protein of unknown function (DUF3311) FOC75_RS01695 ENOG4105E1V na solute symporter FOC75_RS01710 ENOG4108NHD germination protein FOC75_RS01715 ENOG4105CE1 Ferrous iron transport protein b FOC75_RS01720 ENOG4105CE1 Ferrous iron transport protein b FOC75_RS01725 ENOG4105CE1 Ferrous iron transport protein b FOC75_RS01730 ENOG4105CVA phosphate FOC75_RS01735 ENOG4105C8U phosphate abc transporter FOC75_RS01740 ENOG4105E2Z phosphate ABC transporter (Permease FOC75_RS01865 ENOG41080XQ Signal transduction protein with cbs domains FOC75_RS01885 ENOG4105ETU transcriptional activator (TenA FOC75_RS01895 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC75_RS01905 ENOG4108VEU Thiamine monophosphate synthase FOC75_RS01910 ENOG41080HI glycine oxidase FOC75_RS01925 ENOG4105D06 uba thif-type nad fad binding protein FOC75_RS01930 ENOG4105DWF phosphomethylpyrimidine kinase FOC75_RS01980 ENOG4108INS Transcriptional regulator FOC75_RS01995 ENOG4105C7N Xanthine uracil vitamin C permease FOC75_RS02005 ENOG4108PXI ErfK YbiS YcfS YnhG FOC75_RS02040 ENOG4108B31 Spore germination protein FOC75_RS02060 ENOG4107Y03 Nitroreductase FOC75_RS02065 ENOG4105ED1 spovr family FOC75_RS02075 ENOG4108TCS Glutamyl endopeptidase FOC75_RS02085 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC75_RS02090 ENOG4105XTG Pfam:DUF156 FOC75_RS02095 ENOG4105VFE sira family FOC75_RS02100 ENOG4107TPS domain protein FOC75_RS02105 ENOG4105VFE sira family FOC75_RS02110 ENOG41085GJ domain protein FOC75_RS02120 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC75_RS02125 ENOG41087NI Sulfite exporter TauE/SafE FOC75_RS02135 ENOG4108KGH TRANSCRIPTIONal FOC75_RS02160 ENOG4105EMD TRANSCRIPTIONal FOC75_RS02165 ENOG4105VCP PTS System FOC75_RS02170 ENOG4105VZJ PTS System FOC75_RS02190 ENOG41069ER domain protein FOC75_RS02195 ENOG4107RBB ABC transporter, permease FOC75_RS02200 ENOG4105C19 ABC transporter FOC75_RS02230 ENOG4105WEF catalase FOC75_RS02265 ENOG4107T5V SNARE associated Golgi FOC75_RS02300 ENOG4105CUB amino acid FOC75_RS02305 ENOG4107RWR Sodium hydrogen exchanger FOC75_RS02315 ENOG4106KNT transcriptional regulator FOC75_RS02355 ENOG4108YXU transcriptional regulator AsnC family FOC75_RS02370 ENOG4105KPY Small multidrug resistance protein FOC75_RS02395 ENOG4105NF4 modulator of drug activity FOC75_RS02405 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC75_RS02410 ENOG4105E5W Transporter FOC75_RS02420 ENOG4107RKG DJ-1/PfpI family FOC75_RS02425 ENOG4105CH6 catalase FOC75_RS02435 ENOG4105D5Q Arginine ornithine antiporter FOC75_RS02440 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC75_RS02450 ENOG4105C26 Dehydrogenase FOC75_RS02455 ENOG4105BZ1 (ABC) transporter FOC75_RS02460 ENOG4105BZ1 (ABC) transporter FOC75_RS02470 ENOG4105DRP amino acid AbC transporter FOC75_RS02475 ENOG4105CDA abc transporter atp-binding protein FOC75_RS02490 ENOG410839P FOC75_RS02525 ENOG4107FQX Alpha-acetolactate decarboxylase FOC75_RS02545 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC75_RS02550 ENOG4105D4P Coproporphyrinogen iii oxidase FOC75_RS02565 ENOG4105CHH sulfate transporter FOC75_RS02615 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC75_RS02620 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC75_RS02635 ENOG4105CGU Enoyl-CoA hydratase FOC75_RS02655 ENOG4105DER m42 family FOC75_RS02675 ENOG4105CTU Proline racemase FOC75_RS02720 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC75_RS02730 ENOG4108JQ7 (ABC) transporter FOC75_RS02745 ENOG4105CSH Transporter FOC75_RS02755 ENOG4108MRH transcriptional regulatory protein FOC75_RS02765 ENOG4105M6F mutator MutT protein FOC75_RS02825 ENOG4105CDU Replicative dna helicase FOC75_RS02845 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC75_RS02920 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC75_RS02950 ENOG4105CMT Dihydroxyacetone kinase FOC75_RS02960 ENOG4105CMT Dihydroxyacetone kinase FOC75_RS02975 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC75_RS03040 ENOG4105WN5 stage II sporulation protein FOC75_RS03050 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS03060 ENOG4108MJI response regulator FOC75_RS03065 ENOG4105BZU Histidine kinase FOC75_RS03070 ENOG4105BZU Histidine kinase FOC75_RS03130 ENOG4107VRP DNA repair exonuclease FOC75_RS03135 ENOG4106D4I domain protein FOC75_RS03190 ENOG4108MUZ hydrolase FOC75_RS03210 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC75_RS03225 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC75_RS03240 ENOG4105EMN RNA polymerase sigma factor FOC75_RS03250 ENOG4105CNI cell division protein FtsW FOC75_RS03265 ENOG4105C57 major facilitator superfamily FOC75_RS03270 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC75_RS03280 ENOG4105EEM helicase FOC75_RS03285 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC75_RS03310 ENOG4105K59 histidine triad (HIT) protein FOC75_RS03385 ENOG410905X membrane-flanked domain protein FOC75_RS03390 ENOG4105CKV Membrane FOC75_RS03430 ENOG410905X membrane-flanked domain protein FOC75_RS03435 ENOG4105CKV Membrane FOC75_RS03440 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC75_RS03445 ENOG4105BZ4 penicillin-binding protein FOC75_RS03460 ENOG4105C1Q protoporphyrinogen oxidase FOC75_RS03495 ENOG4105ECB domain protein FOC75_RS03515 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) FOC75_RS03525 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC75_RS03535 ENOG4106AXD FOC75_RS03540 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC75_RS03545 ENOG4105DF9 Lipoate-protein, ligase FOC75_RS03555 ENOG4105CEY Amp-dependent synthetase and ligase FOC75_RS03600 ENOG4105CNA YD repeat protein FOC75_RS03615 ENOG4105CNA YD repeat protein FOC75_RS03655 ENOG4107RN3 metallophosphoesterase FOC75_RS03665 ENOG4107TVP HD domain protein FOC75_RS03675 ENOG4108AEY RNA polymerase sigma factor FOC75_RS03680 ENOG41086D8 Transcriptional regulator FOC75_RS03700 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC75_RS03725 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC75_RS03750 ENOG4107QP3 malate synthase g FOC75_RS03780 ENOG4105XVF Competence transcription factor FOC75_RS03845 ENOG4105ERH Fumarylacetoacetate hydrolase FOC75_RS03870 ENOG4105CAQ asparagine synthetase FOC75_RS03875 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FOC75_RS03880 ENOG4105CH6 catalase FOC75_RS03885 ENOG4105BZU Histidine kinase FOC75_RS03905 ENOG4105QNR S1 RNA binding domain protein FOC75_RS03915 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC75_RS03925 ENOG4107AYK membrAne FOC75_RS03930 ENOG41073B9 FOC75_RS03940 ENOG4108KP7 hydrolase FOC75_RS03950 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOC75_RS03975 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC75_RS03980 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC75_RS03995 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC75_RS04010 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC75_RS04015 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC75_RS04025 ENOG4108JQ7 (ABC) transporter FOC75_RS04030 ENOG4105UQX Mate efflux family protein FOC75_RS04050 ENOG4108ZCF integral membrane protein FOC75_RS04060 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC75_RS04070 ENOG4105DPN Oligoendopeptidase f FOC75_RS04085 ENOG4108Z18 K06886 hemoglobin FOC75_RS04090 ENOG4105MIX Adenylate cyclase FOC75_RS04105 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FOC75_RS04110 ENOG4105EMS pseudouridine synthase FOC75_RS04130 ENOG4105K64 Glycosyl transferase, family 2 FOC75_RS04150 ENOG4107TVC Glycosyl transferase, family 2 FOC75_RS04170 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC75_RS04175 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC75_RS04185 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC75_RS04260 ENOG4105CK7 Sodium proline symporter FOC75_RS04270 ENOG4105DDQ anthranilate synthase FOC75_RS04375 ENOG4105C7S Dehydrogenase FOC75_RS04385 ENOG4105VZ8 Transcriptional regulator FOC75_RS04485 ENOG4108NE4 FOC75_RS04520 ENOG4105EFC phage portal protein HK97 family FOC75_RS04540 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC75_RS04555 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) FOC75_RS04565 ENOG4105DZ1 carboxypeptidase FOC75_RS04570 ENOG4105VFR signal peptidase FOC75_RS04605 ENOG4105C26 Dehydrogenase FOC75_RS04615 ENOG4105F38 ABC transporter, permease FOC75_RS04620 ENOG4105D38 putrescine abc transporter FOC75_RS04625 ENOG4107RUE extracellular solute-binding protein family 1 FOC75_RS04635 ENOG4105EYF MMPL domain protein FOC75_RS04645 ENOG4108YBP pseudouridine synthase FOC75_RS04655 ENOG4105K4I Scp-like extracellular FOC75_RS04660 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC75_RS04665 ENOG4105CQB FAD linked oxidase domain protein FOC75_RS04680 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS04685 ENOG4105BZU Histidine kinase FOC75_RS04690 ENOG4105JXH GntR family transcriptional regulator FOC75_RS04710 ENOG4106A3R peptidase FOC75_RS04720 ENOG4108QTI )-transporter FOC75_RS04725 ENOG4107TS3 membrane protein, TerC FOC75_RS04730 ENOG4105CZN Potassium uptake protein FOC75_RS04735 ENOG410681C small acid-soluble spore protein FOC75_RS04740 ENOG4108Z7G MaoC domain protein dehydratase FOC75_RS04760 ENOG4105CHR reductase FOC75_RS04770 ENOG4105MWK D-amino acid dehydrogenase, small subunit FOC75_RS04790 ENOG4105C4Y ABC transporter FOC75_RS04795 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC75_RS04800 ENOG4107RCV ABC transporter, permease FOC75_RS04820 ENOG4105E98 transcriptional regulator DeoR family FOC75_RS04830 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FOC75_RS04840 ENOG4105PXI polysaccharide deacetylase FOC75_RS04850 ENOG4105BZU Histidine kinase FOC75_RS04855 ENOG41090MY MarR family Transcriptional regulator FOC75_RS04865 ENOG4106DF1 FOC75_RS04870 ENOG4105BZU Histidine kinase FOC75_RS04880 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC75_RS04885 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC75_RS04925 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC75_RS04945 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC75_RS04950 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS04955 ENOG4105CZV ABC transporter FOC75_RS04965 ENOG4105CJ1 ABC, transporter FOC75_RS05005 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC75_RS05010 ENOG4105EA8 2-Nitropropane dioxygenase FOC75_RS05015 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC75_RS05025 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC75_RS05050 ENOG4105NQC Flavodoxin FOC75_RS05085 ENOG4107QMU Mate efflux family protein FOC75_RS05090 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC75_RS05120 ENOG4105CZN Potassium uptake protein FOC75_RS05125 ENOG41063Y9 FOC75_RS05130 ENOG4105KBJ sporulation protein ytfj FOC75_RS05150 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC75_RS05155 ENOG4105C7K acetolactate synthase FOC75_RS05160 ENOG4108ZP8 Acetolactate synthase small subunit FOC75_RS05235 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC75_RS05250 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC75_RS05255 ENOG4105E0M Sulfatase FOC75_RS05265 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC75_RS05285 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC75_RS05290 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC75_RS05300 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC75_RS05305 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC75_RS05310 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC75_RS05315 ENOG4105C8J )-transporter FOC75_RS05335 ENOG4105DFD Na H antiporter FOC75_RS05355 ENOG4105ENE Histidine kinase FOC75_RS05360 ENOG4105WH1 Two component transcriptional regulator luxr family FOC75_RS05380 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FOC75_RS05425 ENOG4105CJ3 phosphate transporter FOC75_RS05430 ENOG4107GRR phosphate transport regulator FOC75_RS05435 ENOG4105BZ4 penicillin-binding protein FOC75_RS05450 ENOG4105BZU Histidine kinase FOC75_RS05455 ENOG4105I3N Conserved Protein FOC75_RS05470 ENOG4105BZU Histidine kinase FOC75_RS05505 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC75_RS05510 ENOG4105DZ1 carboxypeptidase FOC75_RS05515 ENOG4108JIC nucleoside recognition domain protein FOC75_RS05525 ENOG4105FE9 pseudouridine synthase FOC75_RS05535 ENOG4107TWT Cytochrome c biogenesis protein FOC75_RS05540 ENOG4105CRE cytochrome C FOC75_RS05545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS05550 ENOG4105BZU Histidine kinase FOC75_RS05555 ENOG4108WBT adenosyltransferase FOC75_RS05560 ENOG41063SB peptidase FOC75_RS05570 ENOG4108SAX Membrane FOC75_RS05585 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC75_RS05590 ENOG4105I7S Abortive infection protein FOC75_RS05600 ENOG4107RGJ metallophosphoesterase FOC75_RS05605 ENOG4107X2D transcriptional regulator, merr family FOC75_RS05610 ENOG4108S6Z Negative regulator of genetic competence FOC75_RS05635 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC75_RS05640 ENOG4105HDK L-asparaginase FOC75_RS05675 ENOG4105S2F FOC75_RS05680 ENOG41065D1 FOC75_RS05710 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC75_RS05725 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC75_RS05735 ENOG4105EAH synthase FOC75_RS05755 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC75_RS05760 ENOG41068YB TPR repeat-containing protein FOC75_RS05775 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC75_RS05780 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC75_RS05785 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit FOC75_RS05815 ENOG4108JYZ YitT family FOC75_RS05820 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC75_RS05835 ENOG4105FJR Lmbe family FOC75_RS05840 ENOG4105CPK Glycosyl transferase (Group 1 FOC75_RS05875 ENOG4105DVT helicase FOC75_RS05880 ENOG4105YAC FOC75_RS05900 ENOG4105CSM endonuclease III FOC75_RS05910 ENOG4105BZ4 penicillin-binding protein FOC75_RS05970 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC75_RS05980 ENOG4105DVT helicase FOC75_RS05985 ENOG4105CTD carboxy-peptidase FOC75_RS06000 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC75_RS06010 ENOG4105C2W permease FOC75_RS06015 ENOG4105DHF Membrane FOC75_RS06020 ENOG410890F Dynamin family FOC75_RS06030 ENOG4108W0I acetyltransferase FOC75_RS06040 ENOG4105KHC sulfurtransferase FOC75_RS06065 ENOG4106032 Glutathionylspermidine synthase FOC75_RS06125 ENOG4105CPK Glycosyl transferase (Group 1 FOC75_RS06140 ENOG4108SZE gCN5-related N-acetyltransferase FOC75_RS06160 ENOG41081VK Ribonuclease FOC75_RS06225 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC75_RS06235 ENOG4107RWR Sodium hydrogen exchanger FOC75_RS06240 ENOG4105CN5 Metallo-Beta-Lactamase FOC75_RS06245 ENOG4108Z5V transcriptional regulator, merr family FOC75_RS06255 ENOG4105H67 Protein of unknown function (DUF421) FOC75_RS06260 ENOG41080C8 DUF218 domain FOC75_RS06315 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC75_RS06325 ENOG4107R0U MotA TolQ exbB proton channel FOC75_RS06330 ENOG4105ER2 Ompa motb domain protein FOC75_RS06335 ENOG4107YTP response regulator receiver protein FOC75_RS06340 ENOG4105CBS Chea signal transduction histidine kinase FOC75_RS06345 ENOG4105DD5 Flagellar motor switch protein FOC75_RS06360 ENOG4105BZU Histidine kinase FOC75_RS06380 ENOG4105E1Q flagellar hook-associated protein FOC75_RS06385 ENOG4105DTJ flagellar hook-associated protein FOC75_RS06390 ENOG4107TPX flagellar hook-associated FOC75_RS06405 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC75_RS06410 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC75_RS06420 ENOG4107U2N Flagellar M-ring protein FOC75_RS06425 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC75_RS06455 ENOG4105BZE flagellar hook protein, FlgE FOC75_RS06470 ENOG4107R88 Chemotaxis protein (CheV) FOC75_RS06480 ENOG4105I03 Flagellin FOC75_RS06485 ENOG4105I03 Flagellin FOC75_RS06490 ENOG4105E4C Lytic transglycosylase catalytic FOC75_RS06500 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC75_RS06505 ENOG4105DD5 Flagellar motor switch protein FOC75_RS06515 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC75_RS06520 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC75_RS06530 ENOG4105D00 flagellar biosynthetic protein flhB FOC75_RS06535 ENOG4105D7B Flagellar biosynthesis protein flha FOC75_RS06540 ENOG4105FZW flagellar biosynthesis regulator FlhF FOC75_RS06545 ENOG4105KTQ flagellar basal-body rod protein FOC75_RS06550 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC75_RS06585 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC75_RS06615 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC75_RS06625 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC75_RS06630 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FOC75_RS06670 ENOG4105CVJ phosphoglycerate mutase FOC75_RS06690 ENOG4105K56 Transcriptional regulator FOC75_RS06700 ENOG4105CAQ asparagine synthetase FOC75_RS06720 ENOG4105PGM cation diffusion facilitator family transporter FOC75_RS06730 ENOG4105DRR Transcriptional regulator, GntR family FOC75_RS06735 ENOG4108UZ3 Transporter FOC75_RS06740 ENOG4105CKI cobalamin synthesis protein FOC75_RS06745 ENOG4108PJD permease FOC75_RS06760 ENOG4105DFD Na H antiporter FOC75_RS06765 ENOG4105VUF Transcriptional regulator FOC75_RS06775 ENOG4105C9Q fumarate hydratase class II FOC75_RS06795 ENOG4107QJQ Mate efflux family protein FOC75_RS06800 ENOG4105EC3 peptidase S51, dipeptidase E FOC75_RS06820 ENOG4107QIV Cytochrome c biogenesis protein FOC75_RS06850 ENOG4106BRA Membrane FOC75_RS06885 ENOG4105CJ1 ABC, transporter FOC75_RS06905 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC75_RS06915 ENOG4108IJ0 Aspartate ammonia-lyase FOC75_RS06920 ENOG4105C6K Malic enzyme FOC75_RS06985 ENOG4105FVX FOC75_RS07025 ENOG4105CSR polyphosphate kinase 2 FOC75_RS07030 ENOG4105DXI Major Facilitator superfamily FOC75_RS07045 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC75_RS07055 ENOG4105EU0 Major facilitator Superfamily FOC75_RS07060 ENOG4105C6T cysteine synthase FOC75_RS07080 ENOG4105C8J )-transporter FOC75_RS07090 ENOG4105X5K response regulator receiver protein FOC75_RS07095 ENOG4105H67 Protein of unknown function (DUF421) FOC75_RS07110 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC75_RS07115 ENOG4105CHR reductase FOC75_RS07120 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC75_RS07125 ENOG4105C7K acetolactate synthase FOC75_RS07130 ENOG4108ZP8 Acetolactate synthase small subunit FOC75_RS07135 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FOC75_RS07145 ENOG4105C7B Threonine dehydratase FOC75_RS07170 ENOG4105C6X Major Facilitator FOC75_RS07175 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC75_RS07185 ENOG4105DY9 regulatoR FOC75_RS07190 ENOG4105CYC Transferase FOC75_RS07240 ENOG41068WN FOC75_RS07260 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC75_RS07275 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FOC75_RS07280 ENOG4105C0X amino acid FOC75_RS07305 ENOG4107RHR regulatoR FOC75_RS07315 ENOG4105D9N nucleoside FOC75_RS07320 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC75_RS07355 ENOG4107RAQ aminopeptidase FOC75_RS07360 ENOG4107R16 Multicopper oxidase FOC75_RS07405 ENOG4108T5E Copper resistance protein FOC75_RS07410 ENOG4105KTB nuclear export factor GLE1 FOC75_RS07415 ENOG4107RT3 EamA-like transporter family FOC75_RS07420 ENOG4105GZI Transcriptional regulator FOC75_RS07425 ENOG4108Z40 Transcriptional regulator FOC75_RS07430 ENOG4107ZXU DSBA oxidoreductase FOC75_RS07435 ENOG4108TVJ Nitroreductase FOC75_RS07445 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC75_RS07450 ENOG4106F5Q Membrane FOC75_RS07465 ENOG4105CKI cobalamin synthesis protein FOC75_RS07485 ENOG4108Z7G MaoC domain protein dehydratase FOC75_RS07490 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC75_RS07500 ENOG4105C0Z ABC transporter FOC75_RS07505 ENOG4108IV0 ABC, transporter FOC75_RS07510 ENOG4105C32 Amino acid ABC transporter (Permease) FOC75_RS07520 ENOG4105SKE transcriptional Regulator LysR family FOC75_RS07550 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC75_RS07555 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC75_RS07560 ENOG4108JJ9 ABC, transporter FOC75_RS07565 ENOG4108JJ8 (ABC) transporter FOC75_RS07610 ENOG4105BZ1 (ABC) transporter FOC75_RS07615 ENOG4105EFI regulatoR FOC75_RS07620 ENOG4105BZU Histidine kinase FOC75_RS07640 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC75_RS07650 ENOG4106AKJ FOC75_RS07665 ENOG4105D6E homoserine dehydrogenase FOC75_RS07690 ENOG4108KGH TRANSCRIPTIONal FOC75_RS07700 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC75_RS07705 ENOG4105BZU Histidine kinase FOC75_RS07720 ENOG4105KT7 mgtC SapB transporter FOC75_RS07725 ENOG4105VRR gCN5-related N-acetyltransferase FOC75_RS07735 ENOG4105DUU IucA IucC family protein FOC75_RS07740 ENOG4105CEY Amp-dependent synthetase and ligase FOC75_RS07755 ENOG4108WBH protein TIM barrel FOC75_RS07760 ENOG4105YWU small acid-soluble spore protein FOC75_RS07770 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC75_RS07820 ENOG4105KRN Transcriptional regulator, abrb family FOC75_RS07830 ENOG4105YVS arsR family transcriptional regulator FOC75_RS07835 ENOG4107SET aldo keto reductase FOC75_RS07840 ENOG4107XZQ multidrug resistance protein FOC75_RS07865 ENOG4105C8Q Methyl-accepting chemotaxis FOC75_RS07880 ENOG4108K88 Membrane FOC75_RS07885 ENOG4108WPJ Ferritin-like domain FOC75_RS07900 ENOG4105DEN Luciferase family FOC75_RS07920 ENOG4107QM2 Aldo Keto reductase FOC75_RS07925 ENOG4105CKI cobalamin synthesis protein FOC75_RS07985 ENOG4105DSE periplasmic solute binding protein FOC75_RS07995 ENOG4105K4T epimerase FOC75_RS08005 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC75_RS08030 ENOG4107TB6 phosphoglycerate mutase FOC75_RS08050 ENOG4107T5V SNARE associated Golgi FOC75_RS08065 ENOG4108PJD permease FOC75_RS08075 ENOG4108S4H thioesterase Superfamily protein FOC75_RS08085 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC75_RS08105 ENOG4105SXS Protein of unknown function (DUF456) FOC75_RS08110 ENOG4105C37 (CBS) domain FOC75_RS08130 ENOG4108Z7R Chaperone CsaA FOC75_RS08150 ENOG4108ZRV stage ii sporulation protein p FOC75_RS08160 ENOG4108VXD carboxy-peptidase FOC75_RS08170 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC75_RS08195 ENOG4108X4Q Hydrolase FOC75_RS08205 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC75_RS08225 ENOG41087PP glycosyltransferase MGT family FOC75_RS08230 ENOG4108JYZ YitT family FOC75_RS08235 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS08265 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC75_RS08325 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS08335 ENOG4105KBJ sporulation protein ytfj FOC75_RS08360 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC75_RS08385 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC75_RS08395 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC75_RS08400 ENOG4105EMN RNA polymerase sigma factor FOC75_RS08415 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) FOC75_RS08435 ENOG4108V06 Glutathione peroxidase FOC75_RS08450 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC75_RS08460 ENOG4108IUE nitrate reductase beta subunit FOC75_RS08465 ENOG4105R3A Nitrate reductase FOC75_RS08480 ENOG4108Z40 Transcriptional regulator FOC75_RS08485 ENOG4105K63 Thioredoxin FOC75_RS08490 ENOG4107QN2 dihydrolipoyl dehydrogenase FOC75_RS08495 ENOG4106HZJ FOC75_RS08500 ENOG4108X3M OsmC Ohr family protein FOC75_RS08505 ENOG4105D3W isochorismatase FOC75_RS08515 ENOG4107V6Q Cyclic nucleotide-binding domain FOC75_RS08520 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC75_RS08525 ENOG4105D06 uba thif-type nad fad binding protein FOC75_RS08530 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC75_RS08535 ENOG4108ZAF Molybdopterin FOC75_RS08555 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC75_RS08560 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC75_RS08565 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC75_RS08570 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC75_RS08575 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC75_RS08580 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC75_RS08615 ENOG4105MCT stage V sporulation protein S FOC75_RS08645 ENOG4105C5H ABC transporter FOC75_RS08660 ENOG4108UUM single-stranded DNA-binding protein FOC75_RS08665 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS08690 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS08700 ENOG4105C75 arginyL-tRNA synthetase FOC75_RS08720 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FOC75_RS08740 ENOG4105C5S asparaginyl-tRNA synthetase FOC75_RS08760 ENOG4105EC2 ftsk spoIIIe FOC75_RS08805 ENOG4105BZW Glycerate kinase FOC75_RS08810 ENOG4107QPK )-transporter FOC75_RS08815 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS08820 ENOG41062D9 Histidine kinase FOC75_RS08835 ENOG4105C8J )-transporter FOC75_RS08855 ENOG4107XGZ Hydrolase FOC75_RS08860 ENOG4105CY2 Citrate transporter FOC75_RS08880 ENOG4105KD7 acetyltransferase FOC75_RS08885 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOC75_RS08910 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC75_RS08930 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC75_RS08945 ENOG4107RVG penicillin-binding protein FOC75_RS08955 ENOG4105E9Q Acyl-transferase FOC75_RS08960 ENOG4108UT2 hemolysin iii FOC75_RS08970 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC75_RS08980 ENOG4108RCR degv family FOC75_RS08985 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC75_RS08990 ENOG4108KF3 Electron transport protein SCO1 SenC FOC75_RS08995 ENOG4107Y70 Heat shock protein FOC75_RS09000 ENOG4105CAQ asparagine synthetase FOC75_RS09015 ENOG4108MES Periplasmic binding protein FOC75_RS09020 ENOG4105F0I Aminotransferase FOC75_RS09050 ENOG4107Y70 Heat shock protein FOC75_RS09055 ENOG4105D8X mechanosensitive ion channel FOC75_RS09060 ENOG4105BZU Histidine kinase FOC75_RS09065 ENOG4105WH1 Two component transcriptional regulator luxr family FOC75_RS09100 ENOG4105CMG Carbohydrate kinase FOC75_RS09105 ENOG4105CMG Carbohydrate kinase FOC75_RS09135 ENOG4108IJ8 ABC transporter FOC75_RS09140 ENOG4105E90 ABC transporter FOC75_RS09175 ENOG4105C37 (CBS) domain FOC75_RS09200 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC75_RS09215 ENOG4107S4Y M20 DapE family protein YgeY FOC75_RS09220 ENOG4108TSC N-acetyltransferase FOC75_RS09225 ENOG4108JUB Transcriptional regulator FOC75_RS09230 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC75_RS09270 ENOG4108N23 SpoOM-related protein FOC75_RS09275 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC75_RS09285 ENOG4105SZ6 Thioredoxin FOC75_RS09300 ENOG4108IBT Inherit from COG: transposase FOC75_RS09405 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC75_RS09445 ENOG4105BZ4 penicillin-binding protein FOC75_RS09450 ENOG4105DP8 Major facilitator superfamily MFS_1 FOC75_RS09455 ENOG4105W8X HesB YadR YfhF-family protein FOC75_RS09465 ENOG4105DXD 2-methylcitrate dehydratase FOC75_RS09470 ENOG4105CR4 methylisocitrate lyase FOC75_RS09475 ENOG4105C1G acyl-Coa dehydrogenase FOC75_RS09480 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC75_RS09490 ENOG4105N14 lysine exporter protein LysE YggA FOC75_RS09495 ENOG4105E39 Enoyl-CoA hydratase FOC75_RS09510 ENOG4107RFY SbcCD D subunit FOC75_RS09515 ENOG4105EYH Exonuclease FOC75_RS09535 ENOG4105FCD Major Facilitator FOC75_RS09540 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC75_RS09545 ENOG4105E4F Isochorismate synthase FOC75_RS09550 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC75_RS09555 ENOG4105WQI isochorismatase FOC75_RS09560 ENOG4105CEY Amp-dependent synthetase and ligase FOC75_RS09565 ENOG4105WQT MbtH domain protein FOC75_RS09570 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC75_RS09585 ENOG4105K70 DNA-binding protein FOC75_RS09605 ENOG4105BZG amino acid carrier protein FOC75_RS09625 ENOG4105FE9 pseudouridine synthase FOC75_RS09630 ENOG4105C22 threonyL-tRNA synthetase FOC75_RS09635 ENOG4105C19 ABC transporter FOC75_RS09645 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC75_RS09665 ENOG4108D32 Methyltransferase FOC75_RS09685 ENOG41081I9 integral membrane protein FOC75_RS09700 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC75_RS09710 ENOG4105EYF MMPL domain protein FOC75_RS09735 ENOG4105WCN acetyltransferase FOC75_RS09765 ENOG4105C1Q protoporphyrinogen oxidase FOC75_RS09775 ENOG41068WN FOC75_RS09785 ENOG4105VEQ Cold shock protein FOC75_RS09805 ENOG410667J hydrolase FOC75_RS09850 ENOG4107V2S Transcriptional regulator FOC75_RS09855 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC75_RS09870 ENOG4105DND Transcriptional regulator FOC75_RS09875 ENOG4108RPX mosc domain containing protein FOC75_RS09890 ENOG4105BZ1 (ABC) transporter FOC75_RS09895 ENOG4105BZ1 (ABC) transporter FOC75_RS09915 ENOG4108JCI Transcriptional regulator FOC75_RS09945 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC75_RS09955 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B FOC75_RS09960 ENOG4108KPJ rna polymerase sigma factor FOC75_RS09985 ENOG4105F32 YngK protein FOC75_RS10010 ENOG4105RD7 BadF BadG BcrA BcrD FOC75_RS10020 ENOG4107STF Involved in phosphonate degradation (By similarity) FOC75_RS10055 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC75_RS10070 ENOG4105C1J atp-dependent rna helicase FOC75_RS10085 ENOG4108RZE Tetr family transcriptional regulator FOC75_RS10105 ENOG41088CC tellurite resistance protein tehB FOC75_RS10120 ENOG4107RA9 decarboxylase FOC75_RS10125 ENOG41090HR transcriptional regulator FOC75_RS10160 ENOG4105CIN aminoacyl-histidine dipeptidase FOC75_RS10185 ENOG4107RF6 penicillin-binding protein FOC75_RS10190 ENOG4107RF6 penicillin-binding protein FOC75_RS10200 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC75_RS10205 ENOG4105ETE Transcriptional regulator (LacI family FOC75_RS10210 ENOG4105IE8 Alpha-ketoglutarate permease FOC75_RS10215 ENOG4105CK5 oxidoreductase FOC75_RS10240 ENOG4105D2N Aldolase FOC75_RS10245 ENOG4105DH8 myo-inositol catabolism FOC75_RS10260 ENOG4105CGH 5'-nucleotidase FOC75_RS10275 ENOG4105VZ8 Transcriptional regulator FOC75_RS10290 ENOG4108VXD carboxy-peptidase FOC75_RS10305 ENOG4106UK0 Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity FOC75_RS10310 ENOG41067SE Tetr family transcriptional regulator FOC75_RS10315 ENOG4105C5H ABC transporter FOC75_RS10320 ENOG4105BZU Histidine kinase FOC75_RS10345 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) FOC75_RS10360 ENOG4105CJ1 ABC, transporter FOC75_RS10370 ENOG4107Z3H Transcriptional regulator, TetR family FOC75_RS10385 ENOG4105C1G acyl-Coa dehydrogenase FOC75_RS10390 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC75_RS10395 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC75_RS10400 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC75_RS10405 ENOG4105E39 Enoyl-CoA hydratase FOC75_RS10410 ENOG4107QX3 carboxylase FOC75_RS10415 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC75_RS10425 ENOG4105WCN acetyltransferase FOC75_RS10430 ENOG4105DBI uridine monophosphokinase FOC75_RS10445 ENOG4105DZ1 carboxypeptidase FOC75_RS10460 ENOG4105T9C HD domain FOC75_RS10470 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC75_RS10520 ENOG4105FQP Beta-lactamase FOC75_RS10530 ENOG4107Y80 Major Facilitator superfamily FOC75_RS10550 ENOG4105CUV Homoserine Kinase FOC75_RS10585 ENOG4105CPQ Dehydrogenase FOC75_RS10605 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FOC75_RS10615 ENOG4105DK7 lysyl-tRNA synthetase FOC75_RS10700 ENOG4105ETU transcriptional activator (TenA FOC75_RS10735 ENOG4105VTR Integrase FOC75_RS10825 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein FOC75_RS10975 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC75_RS11055 ENOG410667J hydrolase FOC75_RS11060 ENOG4105BZU Histidine kinase FOC75_RS11065 ENOG4107RF6 penicillin-binding protein FOC75_RS11100 ENOG4108HGU Histidine kinase FOC75_RS11115 ENOG4105CB2 alcohol dehydrogenase FOC75_RS11120 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC75_RS11125 ENOG4105CJN penicillin-binding protein FOC75_RS11135 ENOG4105FQP Beta-lactamase FOC75_RS11170 ENOG4108V4B ThiJ pfpI FOC75_RS11200 ENOG4107Y80 Major Facilitator superfamily FOC75_RS11215 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC75_RS11235 ENOG4107Y9U Membrane FOC75_RS11275 ENOG4105FCD Major Facilitator FOC75_RS11290 ENOG4105E09 nadh pyrophosphatase FOC75_RS11295 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC75_RS11300 ENOG4108Z4K mutator MutT protein FOC75_RS11335 ENOG4108XI2 Domain of unknown function (DUF1963) FOC75_RS11355 ENOG4108NRW Phospholipase, patatin family FOC75_RS11360 ENOG4105KWG Pfam:DUF1696 FOC75_RS11395 ENOG4105PKS Excinuclease abc c subunit domain protein FOC75_RS11435 ENOG4107VFR oxidoreductase FOC75_RS11485 ENOG4105DY8 decarboxylase FOC75_RS11500 ENOG4108IUM Glycogen debranching enzyme FOC75_RS11525 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC75_RS11535 ENOG4105FDR Membrane FOC75_RS11590 ENOG4105MSI germination protein ypeb FOC75_RS11625 ENOG4107Z3H Transcriptional regulator, TetR family FOC75_RS11645 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC75_RS11665 ENOG4105E98 transcriptional regulator DeoR family FOC75_RS11690 ENOG4107QKR Dehydrogenase FOC75_RS11700 ENOG4107RUY (E1 component), alpha subunit FOC75_RS11710 ENOG4105E1F short-chain dehydrogenase reductase FOC75_RS11715 ENOG4105RHY Pfam:UPF0157 FOC75_RS11755 ENOG4107SQ8 Glycine betaine FOC75_RS11760 ENOG4108IJ7 Glycine betaine FOC75_RS11785 ENOG4105E66 phosphoriboisomerase A FOC75_RS11790 ENOG41082BV acetyltransferase FOC75_RS11795 ENOG4108M1A Chitin-binding protein FOC75_RS11800 ENOG41087PP glycosyltransferase MGT family FOC75_RS11820 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC75_RS11845 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC75_RS11875 ENOG4108Z7F N-acetyltransferase FOC75_RS11895 ENOG4105EEM helicase FOC75_RS11915 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC75_RS11960 ENOG4108M1A Chitin-binding protein FOC75_RS11980 ENOG4105BZG amino acid carrier protein FOC75_RS11985 ENOG4105C26 Dehydrogenase FOC75_RS11990 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC75_RS11995 ENOG4105CTU Proline racemase FOC75_RS12000 ENOG4105CTU Proline racemase FOC75_RS12005 ENOG41080HI glycine oxidase FOC75_RS12015 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein FOC75_RS12045 ENOG4107T5V SNARE associated Golgi FOC75_RS12060 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC75_RS12065 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FOC75_RS12080 ENOG4105DTQ mandelate racemase muconate lactonizing FOC75_RS12125 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC75_RS12130 ENOG4105BZU Histidine kinase FOC75_RS12135 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS12170 ENOG4105DPN Oligoendopeptidase f FOC75_RS12180 ENOG4105EPR degv family FOC75_RS12220 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC75_RS12225 ENOG4106K7D Major facilitator family transporter FOC75_RS12245 ENOG4107BMA Transglycosylase associated protein FOC75_RS12260 ENOG41089UC methyltransferase, type 11 FOC75_RS12300 ENOG4105CHM Aminotransferase FOC75_RS12315 ENOG4108ZMI UPF0477 protein FOC75_RS12330 ENOG4105DVE abc transporter atp-binding protein FOC75_RS12380 ENOG4105C02 permease FOC75_RS12390 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC75_RS12395 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC75_RS12400 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC75_RS12425 ENOG4105E09 nadh pyrophosphatase FOC75_RS12445 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC75_RS12495 ENOG4107VC0 DNA alkylation repair enzyme FOC75_RS12515 ENOG4108ZCF integral membrane protein FOC75_RS12520 ENOG4105E0M Sulfatase FOC75_RS12525 ENOG4105C5H ABC transporter FOC75_RS12535 ENOG4105EYF MMPL domain protein FOC75_RS12540 ENOG41082JN Transcriptional regulator FOC75_RS12560 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC75_RS12570 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC75_RS12590 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FOC75_RS12605 ENOG41069ER domain protein FOC75_RS12615 ENOG4105CY2 Citrate transporter FOC75_RS12620 ENOG4105E39 Enoyl-CoA hydratase FOC75_RS12625 ENOG4105J5T Amp-dependent synthetase and ligase FOC75_RS12630 ENOG4108JUB Transcriptional regulator FOC75_RS12645 ENOG4105D4B ABC, transporter FOC75_RS12655 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC75_RS12665 ENOG4105DKT Transcriptional regulator FOC75_RS12670 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) FOC75_RS12680 ENOG41061GT Aldolase FOC75_RS12705 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC75_RS12735 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FOC75_RS12740 ENOG4105II7 pyrroline-5-carboxylate reductase FOC75_RS12770 ENOG4107258 Transcriptional regulator FOC75_RS12780 ENOG4105E0Y RtcB Protein FOC75_RS12785 ENOG4105ECK Fatty Acid Desaturase FOC75_RS12790 ENOG4105G6Z alkaline phosphatase FOC75_RS12800 ENOG4105VMP Transcriptional regulator FOC75_RS12815 ENOG41090T1 Membrane FOC75_RS12825 ENOG4108WCX response regulator FOC75_RS12835 ENOG41068WN FOC75_RS12860 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC75_RS12875 ENOG4105CSH Transporter FOC75_RS12905 ENOG4105CKK Glycosyl transferase, family 2 FOC75_RS12915 ENOG4105C8Y Acetylornithine aminotransferase FOC75_RS12960 ENOG4108TVJ Nitroreductase FOC75_RS12965 ENOG4105FS7 Transcriptional regulator FOC75_RS12985 ENOG4105ERH Fumarylacetoacetate hydrolase FOC75_RS13000 ENOG41082UD thioesterase Superfamily protein FOC75_RS13005 ENOG4105CEY Amp-dependent synthetase and ligase FOC75_RS13010 ENOG4105CHU acetyl-coa acetyltransferase FOC75_RS13015 ENOG4105E39 Enoyl-CoA hydratase FOC75_RS13020 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC75_RS13025 ENOG4105CS2 ec 3.2.1.21 FOC75_RS13030 ENOG4105VCP PTS System FOC75_RS13035 ENOG4108QVC Component IIC FOC75_RS13050 ENOG4105VZJ PTS System FOC75_RS13060 ENOG4105G9B Transcriptional regulator FOC75_RS13065 ENOG4105D2S major facilitator superfamily FOC75_RS13070 ENOG4105EFZ amidohydrolase FOC75_RS13100 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS13110 ENOG4105C19 ABC transporter FOC75_RS13140 ENOG4108XET gCN5-related N-acetyltransferase FOC75_RS13205 ENOG410635A Membrane FOC75_RS13210 ENOG4105KNA -acetyltransferase FOC75_RS13215 ENOG4108IQI permease FOC75_RS13225 ENOG4105F1N DNA alkylation repair FOC75_RS13255 ENOG4107RF6 penicillin-binding protein FOC75_RS13265 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FOC75_RS13300 ENOG4105P4J Allophanate hydrolase, subunit 1 FOC75_RS13305 ENOG4107258 Transcriptional regulator FOC75_RS13315 ENOG4106N3A copper homeostasis protein cutc FOC75_RS13320 ENOG4108ZRV stage ii sporulation protein p FOC75_RS13325 ENOG4108ZHR arsR family transcriptional regulator FOC75_RS13335 ENOG4105FDT acyl-CoA dehydrogenase FOC75_RS13350 ENOG4105DWD nucleoside recognition domain protein FOC75_RS13380 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC75_RS13445 ENOG4105E2A Dehydrogenase FOC75_RS13455 ENOG4108IJ0 Aspartate ammonia-lyase FOC75_RS13460 ENOG4105HDK L-asparaginase FOC75_RS13465 ENOG4108IMY Transcriptional regulator FOC75_RS13475 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC75_RS13480 ENOG4105CUB amino acid FOC75_RS13490 ENOG4105II7 pyrroline-5-carboxylate reductase FOC75_RS13505 ENOG4108NHD germination protein FOC75_RS13510 ENOG4108Q8B Spore germination protein FOC75_RS13530 ENOG4105CSV Glutaminase FOC75_RS13545 ENOG4105CGH 5'-nucleotidase FOC75_RS13550 ENOG4105CH6 catalase FOC75_RS13560 ENOG4105CHJ isochorismatase hydrolase FOC75_RS13585 ENOG41090MY MarR family Transcriptional regulator FOC75_RS13620 ENOG4108606 TspO/MBR family FOC75_RS13625 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOC75_RS13640 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC75_RS13645 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC75_RS13660 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC75_RS13665 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FOC75_RS13700 ENOG4105D6J arsenicaL-resistance protein FOC75_RS13705 ENOG41085FC arsR family transcriptional regulator FOC75_RS13725 ENOG4105BZU Histidine kinase FOC75_RS13730 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS13745 ENOG4107P5I polyketide synthase FOC75_RS13750 ENOG4108IG5 Transcriptional regulator FOC75_RS13755 ENOG4105CHR reductase FOC75_RS13760 ENOG4108YXU transcriptional regulator AsnC family FOC75_RS13845 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC75_RS13850 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC75_RS13860 ENOG4105IIP Membrane FOC75_RS13875 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS13880 ENOG41062D9 Histidine kinase FOC75_RS13905 ENOG4105K6H D-cysteine desulfhydrase FOC75_RS13930 ENOG4108NNI Beta-lactamase domain-containing protein FOC75_RS13935 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FOC75_RS13945 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC75_RS13965 ENOG4105JQZ Methyltransferase FOC75_RS13980 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) FOC75_RS13985 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC75_RS14000 ENOG4105BZU Histidine kinase FOC75_RS14010 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC75_RS14015 ENOG4105DJB Major Facilitator Superfamily FOC75_RS14020 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FOC75_RS14025 ENOG4107QR9 Iron-sulfur cluster binding protein FOC75_RS14035 ENOG4106P55 Transcriptional regulator FOC75_RS14045 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC75_RS14075 ENOG4105TRI Hydrolase FOC75_RS14110 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC75_RS14145 ENOG4105C44 Serine transporter FOC75_RS14150 ENOG4105EJQ L-serine dehydratase FOC75_RS14165 ENOG4108JPW Aminotransferase FOC75_RS14175 ENOG4105C45 hydrogenase expression formation protein (HypE) FOC75_RS14180 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) FOC75_RS14190 ENOG4105DVH amino acid FOC75_RS14205 ENOG4108JQ1 Dehydrogenase FOC75_RS14225 ENOG4108AEY RNA polymerase sigma factor FOC75_RS14240 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC75_RS14245 ENOG410874W AraC family transcriptional regulator FOC75_RS14265 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC75_RS14305 ENOG4108ISG Major Facilitator FOC75_RS14315 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC75_RS14320 ENOG4105CZM Major Facilitator FOC75_RS14330 ENOG4105RXJ FOC75_RS14335 ENOG4105KPY Small multidrug resistance protein FOC75_RS14340 ENOG4105KBX Transcriptional regulator, TetR family FOC75_RS14350 ENOG4105CRW Short chain fatty acid transporter FOC75_RS14360 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC75_RS14395 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC75_RS14430 ENOG4105EQ0 Major Facilitator superfamily FOC75_RS14435 ENOG4108IND Tetr family transcriptional regulator FOC75_RS14450 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS14455 ENOG4105K59 histidine triad (HIT) protein FOC75_RS14460 ENOG4108Z4K mutator MutT protein FOC75_RS14465 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS14470 ENOG4108Z66 YbaK ebsC protein FOC75_RS14490 ENOG4105KVH Transcriptional regulator FOC75_RS14495 ENOG4108RCM Nitroreductase FOC75_RS14515 ENOG4108PSK reductase FOC75_RS14525 ENOG4105CJ1 ABC, transporter FOC75_RS14585 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC75_RS14590 ENOG4105DKQ ROK family FOC75_RS14595 ENOG4106UW1 Major Facilitator superfamily FOC75_RS14600 ENOG4108UW5 maltose o-acetyltransferase FOC75_RS14610 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC75_RS14650 ENOG4105DMQ Methyltransferase FOC75_RS14660 ENOG4105EV4 Multidrug resistance protein mdtH FOC75_RS14690 ENOG4105C37 (CBS) domain FOC75_RS14705 ENOG4105DDN Pentapeptide repeat-containing protein FOC75_RS14710 ENOG4105XDF Protein of unknown function (DUF1272) FOC75_RS14715 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC75_RS14720 ENOG4105CMG Carbohydrate kinase FOC75_RS14725 ENOG4105C6Z Gluconate FOC75_RS14730 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC75_RS14745 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC75_RS14760 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone FOC75_RS14780 ENOG4105EWI Short-chain dehydrogenase reductase Sdr FOC75_RS14785 ENOG4105D4Y metalloprotease FOC75_RS14820 ENOG4105C44 Serine transporter FOC75_RS14860 ENOG4108TZY GntR Family Transcriptional Regulator FOC75_RS14865 ENOG4105D9R oxidoreductase FOC75_RS14870 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase FOC75_RS14875 ENOG4105KVH Transcriptional regulator FOC75_RS14880 ENOG4105KVH Transcriptional regulator FOC75_RS14915 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC75_RS14925 ENOG4105CHR reductase FOC75_RS14935 ENOG4105KNA -acetyltransferase FOC75_RS14945 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FOC75_RS14950 ENOG4105KVH Transcriptional regulator FOC75_RS15005 ENOG4105KAF membrAne FOC75_RS15030 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC75_RS15080 ENOG4105H3G oxidoreductase FOC75_RS15115 ENOG4105CIS alcohol dehydrogenase FOC75_RS15150 ENOG4108TN2 lmbE family FOC75_RS15160 ENOG4107R3E Citrate transporter FOC75_RS15175 ENOG4108MES Periplasmic binding protein FOC75_RS15180 ENOG4105EHG Permease protein FOC75_RS15185 ENOG4105DQ5 transport system permease protein FOC75_RS15190 ENOG4105NX3 Membrane FOC75_RS15195 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC75_RS15220 ENOG4107CUJ Protein of unknown function (DUF2690) FOC75_RS15230 ENOG4107V2S Transcriptional regulator FOC75_RS15250 ENOG4105C98 muts2 protein FOC75_RS15260 ENOG4105E5K Alpha-amylase FOC75_RS15265 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOC75_RS15270 ENOG4105DPN Oligoendopeptidase f FOC75_RS15275 ENOG4108A04 Beta-lactamase FOC75_RS15305 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC75_RS15330 ENOG41082BM Transcriptional regulator, arsr family FOC75_RS15335 ENOG4105CIS alcohol dehydrogenase FOC75_RS15360 ENOG4105RHY Pfam:UPF0157 FOC75_RS15370 ENOG4105C09 Bile acid FOC75_RS15400 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC75_RS15410 ENOG4105K64 Glycosyl transferase, family 2 FOC75_RS15415 ENOG4105E39 Enoyl-CoA hydratase FOC75_RS15425 ENOG4105KT7 mgtC SapB transporter FOC75_RS15440 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC75_RS15445 ENOG41073R8 VanW family FOC75_RS15455 ENOG4108R1P FOC75_RS15475 ENOG4105VEQ Cold shock protein FOC75_RS15495 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC75_RS15515 ENOG410904N short-chain dehydrogenase reductase FOC75_RS15525 ENOG4106IQC argininosuccinate lyase FOC75_RS15540 ENOG4108IA2 Sodium pantothenate symporter FOC75_RS15550 ENOG4105C26 Dehydrogenase FOC75_RS15555 ENOG4105CHR reductase FOC75_RS15565 ENOG4105EWU Squalene--hopene cyclase FOC75_RS15575 ENOG4105FR1 rard protein FOC75_RS15595 ENOG4105D1F ATP-binding protein FOC75_RS15605 ENOG4108ZAF Molybdopterin FOC75_RS15610 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC75_RS15615 ENOG4105D06 uba thif-type nad fad binding protein FOC75_RS15620 ENOG4105TMB Formate nitrite transporter FOC75_RS15630 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC75_RS15635 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC75_RS15645 ENOG4108JB9 formate dehydrogenase FOC75_RS15650 ENOG4105E1K spore germination protein FOC75_RS15715 ENOG4107QJT sodium dicarboxylate symporter FOC75_RS15720 ENOG4108KGH TRANSCRIPTIONal FOC75_RS15730 ENOG4105EMN RNA polymerase sigma factor FOC75_RS15750 ENOG4105CIG ABC transporter FOC75_RS15760 ENOG4105D9R oxidoreductase FOC75_RS15770 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC75_RS15775 ENOG4105K4P CoA-binding domain protein FOC75_RS15780 ENOG4105C0H protease FOC75_RS15785 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS15795 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC75_RS15805 ENOG4105W8X HesB YadR YfhF-family protein FOC75_RS15835 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC75_RS15840 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC75_RS15850 ENOG4108JJA ABC, transporter FOC75_RS15855 ENOG4108I0Z Aconitate hydratase FOC75_RS15895 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC75_RS15915 ENOG4107F3J Amp-dependent synthetase and ligase FOC75_RS15920 ENOG4107ZYJ bioY protein FOC75_RS15925 ENOG4105CEY Amp-dependent synthetase and ligase FOC75_RS15980 ENOG4107AYK membrAne FOC75_RS15990 ENOG4105BZU Histidine kinase FOC75_RS15995 ENOG4105FBA Phospholipase Carboxylesterase FOC75_RS16000 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC75_RS16005 ENOG4105CK7 Sodium proline symporter FOC75_RS16010 ENOG4105CBC glutamate synthase FOC75_RS16015 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC75_RS16020 ENOG4108VJ1 Transcriptional regulator (CarD family FOC75_RS16025 ENOG4108903 Formimidoylglutamase FOC75_RS16090 ENOG4107QIV Cytochrome c biogenesis protein FOC75_RS16110 ENOG4105CJ1 ABC, transporter FOC75_RS16120 ENOG4107RSM transcriptional regulator FOC75_RS16130 ENOG41067MG lrgb family FOC75_RS16155 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC75_RS16170 ENOG4105BZ1 (ABC) transporter FOC75_RS16175 ENOG4105BZ1 (ABC) transporter FOC75_RS16195 ENOG4105D7V transposase FOC75_RS16210 ENOG4105D5T phosphonate abc transporter FOC75_RS16220 ENOG4105CGH 5'-nucleotidase FOC75_RS16230 ENOG4108SVB resolvase FOC75_RS16250 ENOG4105K7K Transcriptional regulator FOC75_RS16280 ENOG4105C5F glutamine synthetase FOC75_RS16285 ENOG4105KV4 Transcriptional regulator FOC75_RS16290 ENOG4105CXI aluminum resistance protein FOC75_RS16295 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC75_RS16300 ENOG4105EN6 Membrane FOC75_RS16305 ENOG4106F1P AAA ATPase, central domain protein FOC75_RS16335 ENOG41069ER domain protein FOC75_RS16340 ENOG4105DM4 PTS System FOC75_RS16345 ENOG4105DE4 1-phosphofructokinase FOC75_RS16350 ENOG4105E98 transcriptional regulator DeoR family FOC75_RS16355 ENOG4107QW4 alcohol dehydrogenase FOC75_RS16360 ENOG4108SJC Membrane FOC75_RS16370 ENOG4105C85 amino acid FOC75_RS16390 ENOG4105TMB Formate nitrite transporter FOC75_RS16395 ENOG4105K70 DNA-binding protein FOC75_RS16405 ENOG4105C59 p-type ATPase FOC75_RS16410 ENOG410681U heavy metal transport detoxification protein FOC75_RS16415 ENOG4105VPX protein, conserved in bacteria FOC75_RS16425 ENOG4105NIV Esterase FOC75_RS16430 ENOG4105E0A ABC, transporter FOC75_RS16450 ENOG4105CGK Exodeoxyribonuclease III FOC75_RS16460 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC75_RS16465 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC75_RS16495 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC75_RS16500 ENOG4105BZU Histidine kinase FOC75_RS16515 ENOG41067MG lrgb family FOC75_RS16530 ENOG4107TTQ Alpha beta hydrolase fold FOC75_RS16535 ENOG4107YEI lmbE family FOC75_RS16560 ENOG4105F0V Cell wall hydrolase FOC75_RS16565 ENOG4107R6R udp-galactopyranose mutase FOC75_RS16570 ENOG4105E0M Sulfatase FOC75_RS16575 ENOG410890F Dynamin family FOC75_RS16585 ENOG4107QHE Choloylglycine hydrolase FOC75_RS16615 ENOG4105DQU oxidoreductase, subunit beta FOC75_RS16620 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC75_RS16625 ENOG4108IGT Dipeptidase FOC75_RS16630 ENOG4105MCT stage V sporulation protein S FOC75_RS16635 ENOG4105D48 metallophosphoesterase FOC75_RS16660 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC75_RS16675 ENOG4105XZV Protein of unknown function (DUF3243) FOC75_RS16680 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC75_RS16700 ENOG4105UIB (ABC) transporter FOC75_RS16705 ENOG4108JQ9 ABC transporter FOC75_RS16710 ENOG4105DIH basic membrane FOC75_RS16715 ENOG4105FDP GntR family transcriptional regulator FOC75_RS16720 ENOG4107QZI cell division protein FtsK FOC75_RS16730 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC75_RS16740 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC75_RS16750 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC75_RS16755 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC75_RS16760 ENOG4105E35 Dipicolinate synthase subunit A FOC75_RS16770 ENOG4105C1V Peptidase, M16 FOC75_RS16790 ENOG4105DTN riboflavin biosynthesis protein ribF FOC75_RS16795 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) FOC75_RS16805 ENOG4105W7A Protein of unknown function (DUF503) FOC75_RS16815 ENOG4105VHM ribosomal protein FOC75_RS16820 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC75_RS16825 ENOG4105CHV Transcription elongation factor NusA FOC75_RS16835 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC75_RS16845 ENOG4105DZP Membrane-associated zinc metalloprotease FOC75_RS16855 ENOG4105KNE Phosphatidate cytidylyltransferase FOC75_RS16900 ENOG4108HE4 integrase family FOC75_RS16910 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC75_RS16915 ENOG4105C79 DNA protecting protein DprA FOC75_RS16920 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC75_RS16935 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC75_RS16960 ENOG4105VB6 UPF0109 protein FOC75_RS16980 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC75_RS16985 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC75_RS17000 ENOG4105CHR reductase FOC75_RS17005 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC75_RS17020 ENOG4105CB5 ATP-dependent DNA helicase recG FOC75_RS17025 ENOG4105DP4 dak2 domain fusion protein ylov FOC75_RS17030 ENOG4108ZAA Alkaline-shock protein FOC75_RS17045 ENOG4105FJ0 thiamine FOC75_RS17050 ENOG4105DJV ribulose-phosphate 3-epimerase FOC75_RS17055 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC75_RS17060 ENOG4105D9P serine threonine protein kinase FOC75_RS17065 ENOG4108ZF3 Phosphatase FOC75_RS17075 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC75_RS17085 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC75_RS17090 ENOG4105C25 Primosomal protein n' FOC75_RS17095 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC75_RS17115 ENOG4105DSJ YicC domain protein FOC75_RS17130 ENOG4105DC7 peptidase M24 FOC75_RS17210 ENOG4105C34 Pseudouridine synthase FOC75_RS17235 ENOG4105DBK s4 domain protein FOC75_RS17240 ENOG41067XK integral membrane protein FOC75_RS17250 ENOG4105DFA alanine racemase domain protein FOC75_RS17255 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC75_RS17260 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC75_RS17270 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS17280 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC75_RS17285 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC75_RS17290 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FOC75_RS17295 ENOG4105D4A Cell wall formation (By similarity) FOC75_RS17305 ENOG4105CNI cell division protein FtsW FOC75_RS17320 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC75_RS17325 ENOG4105CJN penicillin-binding protein FOC75_RS17330 ENOG4105CJN penicillin-binding protein FOC75_RS17335 ENOG41068DC Essential cell division protein (By similarity) FOC75_RS17370 ENOG4105KNH Nucleic acid-binding protein FOC75_RS17380 ENOG41063PX domain protein FOC75_RS17385 ENOG4105D78 K07001 NTE family protein FOC75_RS17390 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC75_RS17400 ENOG4106H78 methyltransferase FOC75_RS17420 ENOG4107TB6 phosphoglycerate mutase FOC75_RS17435 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC75_RS17450 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS17495 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC75_RS17500 ENOG4105CNI cell division protein FtsW FOC75_RS17515 ENOG4108IAB Phoh family FOC75_RS17535 ENOG4105QA2 FOC75_RS17540 ENOG4105CI3 gtp-binding protein typa FOC75_RS17550 ENOG4105ECY inositol monophosphatase FOC75_RS17570 ENOG4105CXN decarboxylase FOC75_RS17620 ENOG4105CPP Dehydrogenase, E1 component FOC75_RS17635 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC75_RS17640 ENOG4108X4Q Hydrolase FOC75_RS17650 ENOG4105CN5 Metallo-Beta-Lactamase FOC75_RS17655 ENOG4107ZYR domain protein FOC75_RS17690 ENOG4108XRC Protein of unknown function (DUF458) FOC75_RS17700 ENOG4107IN1 Protein of unknown function (DUF1797) FOC75_RS17715 ENOG4105EPM Diguanylate phosphodiesterase FOC75_RS17720 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC75_RS17735 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC75_RS17745 ENOG4105UIN FOC75_RS17800 ENOG4108HGU Histidine kinase FOC75_RS17810 ENOG4105CHM Aminotransferase FOC75_RS17815 ENOG4105FKQ transcriptional regulator FOC75_RS17820 ENOG4105EG2 ABC transporter, permease FOC75_RS17830 ENOG4107FKK extracellular solute-binding protein family 1 FOC75_RS17840 ENOG4105CG3 alpha amylase, catalytic region FOC75_RS17885 ENOG4105CHU acetyl-coa acetyltransferase FOC75_RS17925 ENOG4105DTD Dehydrogenase FOC75_RS17945 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC75_RS17985 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC75_RS17990 ENOG4106TD9 Diguanylate cyclase FOC75_RS18010 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC75_RS18025 ENOG4105CID antiterminator FOC75_RS18045 ENOG4105CE4 GlcNAc 6-P deacetylase FOC75_RS18080 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC75_RS18085 ENOG4105PTM secreted protein FOC75_RS18090 ENOG4105J7I hydrolase FOC75_RS18100 ENOG4105G6R Stage v sporulation protein ae FOC75_RS18110 ENOG4105CZ3 stage V sporulation protein ad FOC75_RS18115 ENOG41090VF Stage v sporulation protein ac FOC75_RS18135 ENOG4105C8J )-transporter FOC75_RS18140 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS18150 ENOG41082AN stage II sporulation protein FOC75_RS18155 ENOG4105DZ1 carboxypeptidase FOC75_RS18160 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS18165 ENOG4105DVE abc transporter atp-binding protein FOC75_RS18195 ENOG4105D7N magnesium and cobalt transport protein CorA FOC75_RS18220 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC75_RS18230 ENOG4105I3K Ferric uptake regulator, Fur family FOC75_RS18235 ENOG4105MZ9 stage II sporulation protein m FOC75_RS18255 ENOG4105CPC Aldo Keto reductase FOC75_RS18265 ENOG4105RHY Pfam:UPF0157 FOC75_RS18285 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC75_RS18295 ENOG4105ETE Transcriptional regulator (LacI family FOC75_RS18300 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC75_RS18320 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC75_RS18325 ENOG4108R6K riboflavin synthase, subunit alpha FOC75_RS18350 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC75_RS18355 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC75_RS18370 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC75_RS18380 ENOG4105DFD Na H antiporter FOC75_RS18385 ENOG4105CGH 5'-nucleotidase FOC75_RS18425 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FOC75_RS18440 ENOG4108IXY short-chain dehydrogenase reductase FOC75_RS18445 ENOG41069FQ Metallo-beta-lactamase superfamily FOC75_RS18450 ENOG4105II7 pyrroline-5-carboxylate reductase FOC75_RS18455 ENOG4105EJQ L-serine dehydratase FOC75_RS18480 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC75_RS18490 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC75_RS18495 ENOG4105D9U N-acetyltransferase FOC75_RS18510 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC75_RS18515 ENOG4108QEG Membrane FOC75_RS18520 ENOG4105CDA abc transporter atp-binding protein FOC75_RS18525 ENOG4105E5Q amino acid AbC transporter FOC75_RS18530 ENOG4108HW3 (ABC) transporter FOC75_RS18540 ENOG4105G7B Protein of unknown function (DUF2992) FOC75_RS18545 ENOG4105E09 nadh pyrophosphatase FOC75_RS18555 ENOG4105C7S Dehydrogenase FOC75_RS18560 ENOG4105CPP Dehydrogenase, E1 component FOC75_RS18580 ENOG4107RDP Dehydrogenase FOC75_RS18590 ENOG4108JUB Transcriptional regulator FOC75_RS18600 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC75_RS18615 ENOG4107QQR Sporulation FOC75_RS18620 ENOG4105S1Z Stage IV sporulation protein B FOC75_RS18625 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC75_RS18635 ENOG4105DX0 Hemolysin A FOC75_RS18645 ENOG4105CTB Polyprenyl synthetase FOC75_RS18670 ENOG4108ZSR alkaline shock protein FOC75_RS18675 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC75_RS18700 ENOG410644B Stage III sporulation protein af FOC75_RS18710 ENOG4105KQ4 Stage iii sporulation protein ad FOC75_RS18715 ENOG4108CQH stage III sporulation protein AC FOC75_RS18720 ENOG4105KR5 Stage iii sporulation protein FOC75_RS18725 ENOG4105CD2 stage iii sporulation protein aa FOC75_RS18750 ENOG4105DC7 peptidase M24 FOC75_RS18765 ENOG4105CBJ Metal-dependent enzyme FOC75_RS18775 ENOG4107YBY Hydrolase FOC75_RS18795 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FOC75_RS18800 ENOG4105WZW rhodanese family FOC75_RS18820 ENOG41080TC multidrug resistance protein FOC75_RS18855 ENOG4105CJ1 ABC, transporter FOC75_RS18860 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS18890 ENOG4105C0D helicase FOC75_RS19115 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FOC75_RS19120 ENOG4105C3R Methionine synthase FOC75_RS19130 ENOG4105C28 cystathionine FOC75_RS19135 ENOG4105C28 cystathionine FOC75_RS19155 ENOG4105C5X domain protein FOC75_RS19165 ENOG4105DKQ ROK family FOC75_RS19175 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC75_RS19190 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC75_RS19200 ENOG4105E2Z phosphate ABC transporter (Permease FOC75_RS19205 ENOG4105C8U phosphate abc transporter FOC75_RS19210 ENOG4105PWN phosphate abc transporter FOC75_RS19215 ENOG4107RF6 penicillin-binding protein FOC75_RS19225 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC75_RS19250 ENOG4105N80 Ferric uptake regulator, Fur family FOC75_RS19260 ENOG4105FDK ABC transporter FOC75_RS19265 ENOG4108JYZ YitT family FOC75_RS19270 ENOG41069ZM Protein of unknown function (DUF2624) FOC75_RS19295 ENOG4105EGD dinuclear metal center protein, YbgI family FOC75_RS19310 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS19315 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC75_RS19345 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC75_RS19350 ENOG4105KG3 cytidine deaminase FOC75_RS19355 ENOG4107YR5 Diacylglycerol kinase FOC75_RS19365 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC75_RS19370 ENOG4105C9A Phoh family FOC75_RS19380 ENOG41068P3 sporulation protein YqfC FOC75_RS19385 ENOG4105KTH gatB Yqey FOC75_RS19395 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC75_RS19400 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC75_RS19430 ENOG4105CSA Coproporphyrinogen iii oxidase FOC75_RS19435 ENOG4105KVH Transcriptional regulator FOC75_RS19460 ENOG4105TQK DNA polymerase iii, delta' subunit FOC75_RS19470 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC75_RS19475 ENOG4108UK2 deaminase FOC75_RS19480 ENOG4105KQC Competence protein FOC75_RS19490 ENOG4105DXX methyltransferase FOC75_RS19500 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC75_RS19510 ENOG410812S Rna-binding protein FOC75_RS19520 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC75_RS19525 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC75_RS19540 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS19560 ENOG4108TVJ Nitroreductase FOC75_RS19575 ENOG4105G6Z alkaline phosphatase FOC75_RS19585 ENOG4108MUZ hydrolase FOC75_RS19620 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC75_RS19625 ENOG4105MIR Phenylalanine 4-monooxygenase FOC75_RS19635 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC75_RS19675 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC75_RS19680 ENOG4108V5C ABC transporter FOC75_RS19690 ENOG4105C0A alcohol dehydrogenase FOC75_RS19695 ENOG4105C28 cystathionine FOC75_RS19725 ENOG4107XRG penicillin-binding protein FOC75_RS19740 ENOG4105CFP Peptidase U32 FOC75_RS19745 ENOG4105XYU peptidase (U32 family) FOC75_RS19755 ENOG4105HHA aminodeoxychorismate lyase FOC75_RS19785 ENOG4105C02 permease FOC75_RS19800 ENOG41060CR FOC75_RS19805 ENOG4105C7H Helicase, RecD TraA family FOC75_RS19820 ENOG4105C3J Cysteine desulfurase FOC75_RS19830 ENOG4105D1H recombination factor protein RarA FOC75_RS19835 ENOG4108VCI transcription factor, rsfa family FOC75_RS19840 ENOG4105CUZ uba thif-type nad fad binding protein FOC75_RS19870 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC75_RS19880 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC75_RS19885 ENOG41076HS cation diffusion facilitator family transporter FOC75_RS19890 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC75_RS19900 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC75_RS19905 ENOG4108QG2 Membrane FOC75_RS19915 ENOG4105VIE preprotein translocase, subunit YajC FOC75_RS19930 ENOG41061AI Protein of unknown function (DUF2905) FOC75_RS19945 ENOG4108HUF Transporter FOC75_RS19975 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC75_RS19980 ENOG4108IYU L-aspartate oxidase FOC75_RS19995 ENOG4108RPX mosc domain containing protein FOC75_RS20000 ENOG4105CQC Prephenate dehydratase FOC75_RS20020 ENOG4105EWM Histidine kinase FOC75_RS20045 ENOG4105X36 (ribosomal) protein FOC75_RS20055 ENOG4105C03 ribonuclease FOC75_RS20070 ENOG4107QMS site-determining protein FOC75_RS20090 ENOG4105DFF Rod shape-determining protein mreb FOC75_RS20110 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC75_RS20115 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FOC75_RS20125 ENOG41068KH stage VI sporulation protein D FOC75_RS20135 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC75_RS20160 ENOG4105K56 Transcriptional regulator FOC75_RS20180 ENOG4108IUQ atp-dependent protease FOC75_RS20210 ENOG4108QCI YvbH-like oligomerisation region FOC75_RS20230 ENOG4105M59 Phosphodiesterase, mj0936 family FOC75_RS20245 ENOG4108XJQ germination protein FOC75_RS20255 ENOG4108PCX Major Facilitator FOC75_RS20265 ENOG4105KBX Transcriptional regulator, TetR family FOC75_RS20280 ENOG4105PFC Transcriptional regulator FOC75_RS20315 ENOG41089UC methyltransferase, type 11 FOC75_RS20320 ENOG410904A RNA polymerase FOC75_RS20345 ENOG41082YX Transcriptional regulator, arsr family FOC75_RS20360 ENOG4105D6J arsenicaL-resistance protein FOC75_RS20385 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC75_RS20410 ENOG4105PFC Transcriptional regulator FOC75_RS20425 ENOG4105DZC cytosine deaminase FOC75_RS20430 ENOG4105DZC cytosine deaminase FOC75_RS20435 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC75_RS20440 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC75_RS20455 ENOG4108JQ7 (ABC) transporter FOC75_RS20460 ENOG4108HRK Histidine kinase FOC75_RS20465 ENOG4105DY9 regulatoR FOC75_RS20475 ENOG41067S9 phage shock protein C, PspC FOC75_RS20480 ENOG4108JCI Transcriptional regulator FOC75_RS20490 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC75_RS20495 ENOG4108Z40 Transcriptional regulator FOC75_RS20500 ENOG4105RHA ABC transporter, permease FOC75_RS20505 ENOG4108IUX (ABC) transporter FOC75_RS20510 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC75_RS20515 ENOG4105ER2 Ompa motb domain protein FOC75_RS20520 ENOG4105E14 MotA TolQ exbB proton channel FOC75_RS20525 ENOG4108VXD carboxy-peptidase FOC75_RS20535 ENOG4105E33 succinate dehydrogenase FOC75_RS20545 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC75_RS20560 ENOG4105K63 Thioredoxin FOC75_RS20565 ENOG4105C10 Electron transfer flavoprotein FOC75_RS20570 ENOG4105BZJ Electron transfer flavoprotein FOC75_RS20575 ENOG41060WC Enoyl-CoA hydratase FOC75_RS20580 ENOG4107Z3H Transcriptional regulator, TetR family FOC75_RS20585 ENOG4105CEY Amp-dependent synthetase and ligase FOC75_RS20595 ENOG4105J76 Periplasmic binding protein FOC75_RS20600 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC75_RS20640 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC75_RS20655 ENOG4105DR4 Methyltransferase FOC75_RS20670 ENOG4105KFN sortase, SrtB family FOC75_RS20675 ENOG4105E0A ABC, transporter FOC75_RS20690 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC75_RS20700 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC75_RS20710 ENOG4105FE9 pseudouridine synthase FOC75_RS20720 ENOG4105DCG PHP domain protein FOC75_RS20770 ENOG4108RWN rrna methyltransferase FOC75_RS20805 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC75_RS20810 ENOG4105CW7 secretion protein, HlyD family FOC75_RS20815 ENOG4108JGH Tetr family transcriptional regulator FOC75_RS20820 ENOG4105CN9 Peptidase m42 family protein FOC75_RS20845 ENOG4105C22 threonyL-tRNA synthetase FOC75_RS20850 ENOG4108TDW sporulation protein YtxC FOC75_RS20875 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC75_RS20880 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FOC75_RS20895 ENOG4105C2M dna polymerase I FOC75_RS20900 ENOG4105BZU Histidine kinase FOC75_RS20905 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC75_RS20925 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC75_RS20930 ENOG4105BZN citrate synthase FOC75_RS20940 ENOG4108REF Sporulation integral membrane protein ytvi FOC75_RS20945 ENOG4105FS0 cytoplasmic membrane protein FOC75_RS20970 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS20975 ENOG4105C6K Malic enzyme FOC75_RS20980 ENOG4105C0B DNA polymerase III (alpha subunit) FOC75_RS20985 ENOG4105VV2 FOC75_RS20995 ENOG4105SFS phosphoesterase RecJ domain protein FOC75_RS21030 ENOG4105DC7 peptidase M24 FOC75_RS21075 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC75_RS21085 ENOG4105VZ8 Transcriptional regulator FOC75_RS21105 ENOG4107YZX Universal stress protein FOC75_RS21145 ENOG4108JYZ YitT family FOC75_RS21175 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC75_RS21180 ENOG4105KBJ sporulation protein ytfj FOC75_RS21195 ENOG4105EFZ amidohydrolase FOC75_RS21205 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC75_RS21230 ENOG4106KR7 LysR family Transcriptional regulator FOC75_RS21240 ENOG4105U5Y Transcriptional regulator FOC75_RS21250 ENOG4105C28 cystathionine FOC75_RS21280 ENOG4105EMN RNA polymerase sigma factor FOC75_RS21295 ENOG4105F1V Acetoin utilization protein FOC75_RS21300 ENOG4105W87 Cbs domain FOC75_RS21305 ENOG4105DGU Histone deacetylase FOC75_RS21310 ENOG4106HB6 Alpha beta hydrolase FOC75_RS21320 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC75_RS21330 ENOG4107SNB ankyrin repeat protein YahD FOC75_RS21335 ENOG4105EP9 oxidoreductase FOC75_RS21365 ENOG4105ETE Transcriptional regulator (LacI family FOC75_RS21385 ENOG4105C88 aminopeptidase FOC75_RS21435 ENOG4108VDD TRNA binding domain protein FOC75_RS21465 ENOG4105C8F Beta-lactamase domain protein FOC75_RS21480 ENOG4108V15 phosphotransferase enzyme family FOC75_RS21485 ENOG4108IUM Glycogen debranching enzyme FOC75_RS21495 ENOG4107QSE Dipeptidase FOC75_RS21500 ENOG4105YW5 deoR family transcriptional regulator FOC75_RS21515 ENOG4105CBX hi0933 family FOC75_RS21550 ENOG4108VJ1 Transcriptional regulator (CarD family FOC75_RS21555 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC75_RS21575 ENOG4108ZAF Molybdopterin FOC75_RS21580 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC75_RS21585 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC75_RS21595 ENOG4105D06 uba thif-type nad fad binding protein FOC75_RS21600 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC75_RS21620 ENOG41085GJ domain protein FOC75_RS21630 ENOG4105DWV Homoserine O-trans-acetylase FOC75_RS21640 ENOG4108B31 Spore germination protein FOC75_RS21670 ENOG410605W Major Facilitator FOC75_RS21675 ENOG4107S91 Sodium hydrogen exchanger FOC75_RS21680 ENOG4105NCW Trka-c domain protein FOC75_RS21695 ENOG4105C19 ABC transporter FOC75_RS21715 ENOG4105N5T Radical SAM Protein FOC75_RS21725 ENOG4105CIG ABC transporter FOC75_RS21755 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC75_RS21760 ENOG4108Z0R Transferase FOC75_RS21765 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC75_RS21770 ENOG4105BZF Glycosyl transferase (Group 1 FOC75_RS21780 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOC75_RS21835 ENOG4105EGD dinuclear metal center protein, YbgI family FOC75_RS21840 ENOG4105BZU Histidine kinase FOC75_RS21845 ENOG4105BZU Histidine kinase FOC75_RS21850 ENOG4107S9D Alpha beta hydrolase FOC75_RS21855 ENOG4107T7U Sulfatase FOC75_RS21870 ENOG4105D2X ABC transporter substrate-binding protein FOC75_RS21880 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC75_RS21895 ENOG4107XGZ Hydrolase FOC75_RS21940 ENOG4108V2W Carbonate dehydratase FOC75_RS21945 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC75_RS21950 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC75_RS21995 ENOG41087YS Phage shock protein A FOC75_RS22035 ENOG4105BZU Histidine kinase FOC75_RS22040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS22065 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC75_RS22070 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC75_RS22095 ENOG4107ZTW SNARE associated Golgi FOC75_RS22110 ENOG4105C19 ABC transporter FOC75_RS22115 ENOG41086D8 Transcriptional regulator FOC75_RS22180 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC75_RS22210 ENOG4105DTQ mandelate racemase muconate lactonizing FOC75_RS22220 ENOG4108IPT Naphthoate synthase FOC75_RS22225 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC75_RS22235 ENOG4105E4F Isochorismate synthase FOC75_RS22240 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC75_RS22250 ENOG4105VEQ Cold shock protein FOC75_RS22310 ENOG4105JVQ RNA Polymerase FOC75_RS22405 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC75_RS22440 ENOG4105KT7 mgtC SapB transporter FOC75_RS22445 ENOG4107PBV potassium channel FOC75_RS22460 ENOG4105WG9 Conserved Protein FOC75_RS22470 ENOG4105CHM Aminotransferase FOC75_RS22475 ENOG4108ZB6 transcriptional regulator AsnC family FOC75_RS22480 ENOG4105C5I Dehydrogenase FOC75_RS22485 ENOG4108MUZ hydrolase FOC75_RS22495 ENOG4105C87 Aminotransferase class I and II FOC75_RS22510 ENOG4105Y38 Kinase-associated protein B FOC75_RS22520 ENOG4107R3E Citrate transporter FOC75_RS22540 ENOG4105KA0 thioesterase Superfamily protein FOC75_RS22555 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC75_RS22575 ENOG41069ER domain protein FOC75_RS22595 ENOG4105CEP NADH dehydrogenase FOC75_RS22625 ENOG4105EWC Purine nucleoside phosphorylase FOC75_RS22635 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC75_RS22660 ENOG4108JJA ABC, transporter FOC75_RS22665 ENOG4105C4B ABC transporter, permease FOC75_RS22670 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC75_RS22695 ENOG41083MR nifu domain-containing protein FOC75_RS22710 ENOG4108W5N phosphatidylglycerophosphatase a FOC75_RS22720 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC75_RS22730 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC75_RS22745 ENOG4105CBT Fructose-1,6-bisphosphatase FOC75_RS22760 ENOG4105MMD transcriptional regulator FOC75_RS22765 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC75_RS22770 ENOG4107TXC Transcriptional regulator FOC75_RS22775 ENOG41090T1 Membrane FOC75_RS22800 ENOG4105FAA peptidase M23 FOC75_RS22810 ENOG4105KZD Domain of unknown function (DUF1805) FOC75_RS22815 ENOG4107R8B 5'-nucleotidase FOC75_RS22820 ENOG4105DIW FeS assembly protein SUFB FOC75_RS22825 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC75_RS22830 ENOG4105C9B Cysteine desulfurase FOC75_RS22835 ENOG4105JRK feS assembly protein SufD FOC75_RS22840 ENOG4105C3K feS assembly ATPase SufC FOC75_RS22845 ENOG4105D01 (LipO)protein FOC75_RS22850 ENOG4105D01 (LipO)protein FOC75_RS22855 ENOG4108UMI ABC transporter, permease FOC75_RS22885 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC75_RS22955 ENOG4108IMY Transcriptional regulator FOC75_RS22965 ENOG4108W8B Beta-lactamase domain protein FOC75_RS22970 ENOG4105C1G acyl-Coa dehydrogenase FOC75_RS22980 ENOG4105CHU acetyl-coa acetyltransferase FOC75_RS22995 ENOG4105DZ1 carboxypeptidase FOC75_RS23015 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC75_RS23035 ENOG4108SUT Major Facilitator Superfamily FOC75_RS23040 ENOG4107R7I amino acid FOC75_RS23050 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC75_RS23060 ENOG4107AYK membrAne FOC75_RS23095 ENOG4107ZTW SNARE associated Golgi FOC75_RS23105 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC75_RS23110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS23115 ENOG4105BZU Histidine kinase FOC75_RS23135 ENOG4105C8Q Methyl-accepting chemotaxis FOC75_RS23140 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC75_RS23145 ENOG4105VG1 fes assembly suf system protein FOC75_RS23150 ENOG4105D4Y metalloprotease FOC75_RS23170 ENOG4107S91 Sodium hydrogen exchanger FOC75_RS23175 ENOG4105NCW Trka-c domain protein FOC75_RS23185 ENOG4108RMU ferritin dps family protein FOC75_RS23200 ENOG4108URH decarboxylase FOC75_RS23220 ENOG4105D9N nucleoside FOC75_RS23225 ENOG4105D9N nucleoside FOC75_RS23235 ENOG4108RYK Nad-dependent epimerase dehydratase FOC75_RS23255 ENOG4105CV8 reductase FOC75_RS23260 ENOG4105F27 Major Facilitator FOC75_RS23265 ENOG4105KVH Transcriptional regulator FOC75_RS23280 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FOC75_RS23285 ENOG4105D4A Cell wall formation (By similarity) FOC75_RS23310 ENOG4105C8Q Methyl-accepting chemotaxis FOC75_RS23340 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC75_RS23360 ENOG4108IPW abc transporter atp-binding protein FOC75_RS23365 ENOG4105CM4 permease protein FOC75_RS23380 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS23400 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC75_RS23410 ENOG4105XZU Preprotein translocase, subunit SecG FOC75_RS23415 ENOG41067MG lrgb family FOC75_RS23465 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS23485 ENOG41090VF Stage v sporulation protein ac FOC75_RS23490 ENOG4105CZ3 stage V sporulation protein ad FOC75_RS23505 ENOG4105H67 Protein of unknown function (DUF421) FOC75_RS23515 ENOG4105KRI phosphocarrier protein (HPr FOC75_RS23525 ENOG4105CHW UPF0052 protein FOC75_RS23535 ENOG4108Z4K mutator MutT protein FOC75_RS23545 ENOG4105C3M thioredoxin reductase FOC75_RS23555 ENOG4108S4C acetyltransferase FOC75_RS23575 ENOG41086DT Membrane protein of unknown function FOC75_RS23585 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC75_RS23590 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC75_RS23605 ENOG4107TXC Transcriptional regulator FOC75_RS23635 ENOG4105HMI Membrane FOC75_RS23640 ENOG4105DUM transcriptional regulator, lysR family FOC75_RS23650 ENOG4108WS4 fmn reductase FOC75_RS23665 ENOG4105BZ1 (ABC) transporter FOC75_RS23675 ENOG4105CN1 protease FOC75_RS23680 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC75_RS23685 ENOG4105CAK Cell division ATP-binding protein ftsE FOC75_RS23705 ENOG4105MS2 ribosomal subunit Interface protein FOC75_RS23710 ENOG4105VEQ Cold shock protein FOC75_RS23715 ENOG41081UC Inherit from COG: Competence protein FOC75_RS23730 ENOG4105KVH Transcriptional regulator FOC75_RS23740 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC75_RS23745 ENOG4108KGH TRANSCRIPTIONal FOC75_RS23750 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC75_RS23755 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOC75_RS23760 ENOG4105ESV Glycosyl transferase, family 4 FOC75_RS23770 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC75_RS23790 ENOG4105F8D glycoside hydrolase family 4 FOC75_RS23795 ENOG4105VCP PTS System FOC75_RS23800 ENOG4105CK1 PTS System FOC75_RS23810 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FOC75_RS23820 ENOG4105VCP PTS System FOC75_RS23830 ENOG4105VZJ PTS System FOC75_RS23845 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC75_RS23850 ENOG4105ECB domain protein FOC75_RS23855 ENOG4107RSM transcriptional regulator FOC75_RS23910 ENOG4105DAA L-lactate FOC75_RS23920 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC75_RS23930 ENOG4105E0M Sulfatase FOC75_RS23955 ENOG4107R8N Glycosyl transferase, family 2 FOC75_RS23960 ENOG4105C94 Transporter FOC75_RS23965 ENOG41069ER domain protein FOC75_RS23990 ENOG4105KBK Zinc finger, swim domain protein FOC75_RS23995 ENOG4105C0D helicase FOC75_RS24025 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS24040 ENOG4107RBB ABC transporter, permease FOC75_RS24045 ENOG4105C19 ABC transporter FOC75_RS24055 ENOG4105CXY transporter FOC75_RS24070 ENOG4105BZU Histidine kinase FOC75_RS24075 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS24080 ENOG4105CMR udp-glucose 4-epimerase FOC75_RS24095 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC75_RS24100 ENOG4107VDP teichoic acid biosynthesis FOC75_RS24105 ENOG4105EY8 ABC transporter FOC75_RS24115 ENOG4107SJB teichoic acid biosynthesis FOC75_RS24120 ENOG4107SJB teichoic acid biosynthesis FOC75_RS24125 ENOG4107RZX Teichoic acid biosynthesis protein FOC75_RS24130 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase FOC75_RS24140 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC75_RS24145 ENOG4107BJW polysaccharide deacetylase FOC75_RS24155 ENOG4105FRN stage II sporulation protein FOC75_RS24170 ENOG4105DY9 regulatoR FOC75_RS24190 ENOG4106778 Protein of unknown function (DUF1146) FOC75_RS24195 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC75_RS24200 ENOG4105C8S subunit m FOC75_RS24205 ENOG4105D65 subunit l FOC75_RS24230 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC75_RS24235 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC75_RS24250 ENOG4105BZU Histidine kinase FOC75_RS24300 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC75_RS24305 ENOG41062M3 atp synthase FOC75_RS24335 ENOG4108YZG isomerase FOC75_RS24350 ENOG4108VGI doxx family FOC75_RS24355 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC75_RS24370 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC75_RS24380 ENOG4108ZXQ stage ii sporulation protein r FOC75_RS24385 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC75_RS24405 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC75_RS24410 ENOG4105CBT Fructose-1,6-bisphosphatase FOC75_RS24450 ENOG4105C1G acyl-Coa dehydrogenase FOC75_RS24455 ENOG4105C1G acyl-Coa dehydrogenase FOC75_RS24460 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC75_RS24470 ENOG4105DF6 Fe-S oxidoreductase FOC75_RS24485 ENOG4105BZU Histidine kinase FOC75_RS24515 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC75_RS24525 ENOG4105IIU Aminopeptidase FOC75_RS24545 ENOG4105EMN RNA polymerase sigma factor FOC75_RS24555 ENOG410684U Domain of unknown function (DUF1934) FOC75_RS24575 ENOG4105CYW agmatinase FOC75_RS24585 ENOG4105DXB Major Facilitator superfamily FOC75_RS24590 ENOG4107SWG transcriptional regulator MERR family FOC75_RS24595 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC75_RS24600 ENOG4105BZ4 penicillin-binding protein FOC75_RS24605 ENOG4108XFG YwhD family FOC75_RS24610 ENOG4108Z4T Peptidase M50 FOC75_RS24615 ENOG41069HH 4-oxalocrotonate tautomerase FOC75_RS24620 ENOG4105DCI Phosphohydrolase FOC75_RS24625 ENOG4108MES Periplasmic binding protein FOC75_RS24630 ENOG4105E0A ABC, transporter FOC75_RS24635 ENOG4105EHG Permease protein FOC75_RS24640 ENOG4105DQ5 transport system permease protein FOC75_RS24650 ENOG4108VCI transcription factor, rsfa family FOC75_RS24670 ENOG4108IJ2 phosphate acetyltransferase FOC75_RS24685 ENOG4108VKI Cell wall hydrolase FOC75_RS24705 ENOG4107SVH Potassium channel protein FOC75_RS24715 ENOG410667J hydrolase FOC75_RS24720 ENOG4105VCH membrane FOC75_RS24730 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC75_RS24735 ENOG4105CJ1 ABC, transporter FOC75_RS24740 ENOG41090WU lipolytic protein G-D-S-L family FOC75_RS24755 ENOG4105D6E homoserine dehydrogenase FOC75_RS24780 ENOG4108Y4K DNA-binding transcriptional activator FOC75_RS24790 ENOG4105WH1 Two component transcriptional regulator luxr family FOC75_RS24795 ENOG4105BZU Histidine kinase FOC75_RS24800 ENOG4105DWF phosphomethylpyrimidine kinase FOC75_RS24805 ENOG4105BZU Histidine kinase FOC75_RS24810 ENOG4105VCD cytoplasmic protein FOC75_RS24815 ENOG4105D22 carbon starvation protein FOC75_RS24820 ENOG4105DY9 regulatoR FOC75_RS24825 ENOG41079KZ Major Facilitator Superfamily FOC75_RS24845 ENOG4105EN6 Membrane FOC75_RS24850 ENOG4106YBV Methyl-accepting chemotaxis FOC75_RS24860 ENOG4108S4H thioesterase Superfamily protein FOC75_RS24870 ENOG4105JEU Glycosyl transferase, family 2 FOC75_RS24875 ENOG4105C5H ABC transporter FOC75_RS24895 ENOG4105CKK Glycosyl transferase, family 2 FOC75_RS24900 ENOG41067SE Tetr family transcriptional regulator FOC75_RS24910 ENOG4105E0X reductase FOC75_RS24915 ENOG4106F5Q Membrane FOC75_RS24930 ENOG4105DY9 regulatoR FOC75_RS24935 ENOG4108HRK Histidine kinase FOC75_RS24940 ENOG4107RGD Major Facilitator superfamily FOC75_RS24955 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC75_RS24965 ENOG4105IW1 AmiS UreI transporter FOC75_RS24975 ENOG4105CMR udp-glucose 4-epimerase FOC75_RS24980 ENOG4108UT2 hemolysin iii FOC75_RS24990 ENOG4105C1J atp-dependent rna helicase FOC75_RS25005 ENOG4105DPN Oligoendopeptidase f FOC75_RS25025 ENOG4105C0H protease FOC75_RS25030 ENOG4105Q2H domain protein FOC75_RS25045 ENOG4105BZU Histidine kinase FOC75_RS25050 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS25080 ENOG4105CDU Replicative dna helicase FOC75_RS25090 ENOG4105BZR domain protein FOC75_RS25095 ENOG4108XMW Membrane FOC75_RS25105 ENOG4108UUM single-stranded DNA-binding protein FOC75_RS25115 ENOG4105C3G gtp-binding protein FOC75_RS25120 ENOG4105VDK protein, conserved in bacteria FOC75_RS25125 ENOG4105D8X mechanosensitive ion channel FOC75_RS25130 ENOG4108ZDA Sporulation protein YyaC FOC75_RS25135 ENOG4105FA0 parb-like partition protein FOC75_RS25140 ENOG4107QJE Chromosome Partitioning Protein FOC75_RS25170 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC75_RS25190 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC75_RS25195 ENOG410848D S4 domain protein YaaA FOC75_RS25210 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC75_RS25245 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC75_RS25280 ENOG4105ZMH deoxynucleoside kinase FOC75_RS25290 ENOG4105GTG Isochorismatase FOC75_RS25295 ENOG4108Z6B deaminase FOC75_RS25305 ENOG4105C6E dna polymerase iii FOC75_RS25325 ENOG41067KS pro-sigma K processing FOC75_RS25360 ENOG4105CXN decarboxylase FOC75_RS25370 ENOG4105FA2 dna polymerase iii FOC75_RS25375 ENOG4105MA4 psp1 domain protein FOC75_RS25385 ENOG41060K3 Methyltransferase FOC75_RS25395 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC75_RS25400 ENOG4105KRN Transcriptional regulator, abrb family FOC75_RS25410 ENOG4105F8V Hydrolase, tatD family FOC75_RS25415 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC75_RS25425 ENOG4105XFA sporulation peptidase YabG FOC75_RS25430 ENOG4105W42 Veg protein FOC75_RS25445 ENOG4105DFT pur operon repressor FOC75_RS25450 ENOG4105KME endoribonuclease L-psp FOC75_RS25480 ENOG4108JA2 transcriptioN-repair coupling factor FOC75_RS25485 ENOG4108M14 stage v sporulation protein t FOC75_RS25495 ENOG4108IY2 MazG family FOC75_RS25500 ENOG41082I2 s4 domain protein FOC75_RS25505 ENOG4105VYY sporulation protein yabp FOC75_RS25520 ENOG41060GV RNA binding s1 domain protein FOC75_RS25545 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC75_RS25550 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC75_RS25565 ENOG4105C6T cysteine synthase FOC75_RS25570 ENOG4105CRQ synthase (Component I) FOC75_RS25575 ENOG4105DDQ anthranilate synthase FOC75_RS25580 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC75_RS25585 ENOG4105EEI dihydropteroate synthase FOC75_RS25590 ENOG4105KRF dihydroneopterin aldolase FOC75_RS25595 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC75_RS25605 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC75_RS25695 ENOG4108Z0C Uvrb UvrC protein FOC75_RS25710 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC75_RS25720 ENOG4105CTP PilT protein domain protein FOC75_RS25740 ENOG4105D7W serine acetyltransferase FOC75_RS25755 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC75_RS25760 ENOG4105M0M Tetracycline resistance protein FOC75_RS25765 ENOG4105QIV RNA polymerase FOC75_RS25780 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC75_RS25805 ENOG4107Y49 methyltransferase FOC75_RS25820 ENOG4105XPM ribosomal protein FOC75_RS25950 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC75_RS25960 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC75_RS26005 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC75_RS26035 ENOG4105D1F ATP-binding protein FOC75_RS26050 ENOG4108NMV polysaccharide deacetylase FOC75_RS26130 ENOG4105C8B TIGR00159 family FOC75_RS26135 ENOG4107U5W ybbr family FOC75_RS26160 ENOG4108VQT Alpha beta hydrolase fold protein FOC75_RS26170 ENOG4105CMG Carbohydrate kinase FOC75_RS26180 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOC75_RS26185 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein FOC75_RS26215 ENOG4108PSK reductase FOC75_RS26220 ENOG4108UMI ABC transporter, permease FOC75_RS26225 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC75_RS26230 ENOG4105D01 (LipO)protein FOC75_RS26245 ENOG4105IQ5 FAD linked oxidase domain protein FOC75_RS26260 ENOG4105C2C drug resistance transporter, Bcr CflA FOC75_RS26275 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC75_RS26280 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC75_RS26285 ENOG4105C3U ABC transporter FOC75_RS26290 ENOG4108JQ7 (ABC) transporter FOC75_RS26315 ENOG4105U5Y Transcriptional regulator FOC75_RS26325 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC75_RS26330 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC75_RS26340 ENOG4105II7 pyrroline-5-carboxylate reductase FOC75_RS26345 ENOG4107XDY Nicotinamide Mononucleotide Transporter FOC75_RS26355 ENOG4105E0C molybdate abc transporter FOC75_RS26360 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC75_RS26365 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC75_RS26395 ENOG4105F6E Acyl-transferase FOC75_RS26415 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC75_RS26425 ENOG4108RE7 deoxyribonuclease FOC75_RS26430 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC75_RS26455 ENOG4105C5H ABC transporter FOC75_RS26460 ENOG4105BZU Histidine kinase FOC75_RS26465 ENOG4105WH1 Two component transcriptional regulator luxr family FOC75_RS26470 ENOG4105CJ1 ABC, transporter FOC75_RS26475 ENOG41090VJ ABC-2 type transporter FOC75_RS26480 ENOG4108KYE ABC-2 type transporter FOC75_RS26495 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC75_RS26505 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC75_RS26510 ENOG4105C3U ABC transporter FOC75_RS26515 ENOG4108JQ7 (ABC) transporter FOC75_RS26520 ENOG410667J hydrolase FOC75_RS26550 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC75_RS26555 ENOG4105ERH Fumarylacetoacetate hydrolase FOC75_RS26565 ENOG4108SC4 )-transporter FOC75_RS26570 ENOG4105CPF Cell wall formation (By similarity) FOC75_RS26575 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC75_RS26590 ENOG4107ZXI Rhomboid family FOC75_RS26600 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC75_RS26605 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC75_RS26615 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC75_RS26715 ENOG4105K8N protein family UPF0079, ATPase FOC75_RS26720 ENOG41072GX Peptidase M22 Glycoprotease FOC75_RS26725 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC75_RS26735 ENOG4105C5H ABC transporter FOC75_RS26750 ENOG4108TYN CAAX amino terminal protease family protein FOC75_RS26770 ENOG4105C7N Xanthine uracil vitamin C permease FOC75_RS26780 ENOG4105BZU Histidine kinase FOC75_RS26805 ENOG4107ZXU DSBA oxidoreductase FOC75_RS26850 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC75_RS26870 ENOG4105SX7 Transporter FOC75_RS26895 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC75_RS26900 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC75_RS26905 ENOG4105C83 adenylosuccinate lyase FOC75_RS26915 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC75_RS26940 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC75_RS26950 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC75_RS26975 ENOG4105C4R Atp-dependent dna helicase FOC75_RS27005 ENOG4108W2Y isochorismatase FOC75_RS27010 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC75_RS27015 ENOG4108UMI ABC transporter, permease FOC75_RS27020 ENOG4105D01 (LipO)protein FOC75_RS27040 ENOG410834F Transcriptional regulator FOC75_RS27045 ENOG4107I77 yiaA/B two helix domain FOC75_RS27065 ENOG4105CBD Diacylglycerol kinase FOC75_RS27070 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC75_RS27075 ENOG4108JPW Aminotransferase FOC75_RS27085 ENOG4105C26 Dehydrogenase FOC75_RS27090 ENOG4105KPY Small multidrug resistance protein FOC75_RS27110 ENOG4105D9N nucleoside FOC75_RS27115 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC75_RS27130 ENOG4108W15 Protein of unknown function (DUF1456) FOC75_RS27145 ENOG4105DTQ mandelate racemase muconate lactonizing FOC75_RS27155 ENOG4105DFD Na H antiporter FOC75_RS27175 ENOG4105D3R alkyl hydroperoxide reductase FOC75_RS27195 ENOG4105EHG Permease protein FOC75_RS27200 ENOG4105DQ5 transport system permease protein FOC75_RS27205 ENOG4108V5C ABC transporter FOC75_RS27225 ENOG4106UIA FOC75_RS27230 ENOG4106UIA FOC75_RS27255 ENOG4105BZU Histidine kinase FOC75_RS27275 ENOG410756H nucleotidyltransferase FOC75_RS27280 ENOG4105D2S major facilitator superfamily FOC75_RS27295 ENOG4105E5Q amino acid AbC transporter FOC75_RS27300 ENOG4105EAB amino acid AbC transporter FOC75_RS27310 ENOG4105C8Q Methyl-accepting chemotaxis FOC75_RS27335 ENOG4105C5B carbamate kinase FOC75_RS27355 ENOG4105CI1 PTS System FOC75_RS27385 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC75_RS27400 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC75_RS27415 ENOG4105C5H ABC transporter FOC75_RS27445 ENOG41062JF Transcriptional regulator FOC75_RS27465 ENOG4105DEU major facilitator superfamily FOC75_RS27495 ENOG4108N0M stress protein FOC75_RS27500 ENOG4106FN3 tellurium resistance protein FOC75_RS27505 ENOG4106FN3 tellurium resistance protein FOC75_RS27510 ENOG4107TS3 membrane protein, TerC FOC75_RS27515 ENOG4108TTB tellurium resistance protein FOC75_RS27535 ENOG4105KJF protein tyrosine phosphatase FOC75_RS27545 ENOG4107U9T Pfam:Ribonuclease_BN FOC75_RS27550 ENOG4105C59 p-type ATPase FOC75_RS27555 ENOG4108IPJ Membrane FOC75_RS27580 ENOG4107ZTW SNARE associated Golgi FOC75_RS27595 ENOG410606W general stress protein FOC75_RS27600 ENOG4105UPD Calcium Proton FOC75_RS27635 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC75_RS27685 ENOG4108A04 Beta-lactamase FOC75_RS27700 ENOG4105CKK Glycosyl transferase, family 2 FOC75_RS27705 ENOG4107QQG Dehydrogenase FOC75_RS27710 ENOG4105C3I Nad-dependent epimerase dehydratase FOC75_RS27730 ENOG4105F1A Pyruvate formate-lyase FOC75_RS27825 ENOG4105K63 Thioredoxin FOC75_RS27835 ENOG4105EAB amino acid AbC transporter FOC75_RS27840 ENOG4105E5Q amino acid AbC transporter FOC75_RS27845 ENOG4105CDA abc transporter atp-binding protein FOC75_RS27855 ENOG4107R16 Multicopper oxidase FOC75_RS27860 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC75_RS27865 ENOG4105BZU Histidine kinase FOC75_RS27875 ENOG4108ZRV stage ii sporulation protein p FOC75_RS27930 ENOG4105D9M gamma-glutamylcysteine synthetase FOC75_RS27940 ENOG4105C4W S-formylglutathione hydrolase FOC75_RS27950 ENOG4105KVH Transcriptional regulator FOC75_RS27965 ENOG4105E1K spore germination protein FOC75_RS27970 ENOG4108B31 Spore germination protein FOC75_RS27990 ENOG4108QY0 Membrane FOC75_RS28005 ENOG4105CZ3 stage V sporulation protein ad FOC75_RS28010 ENOG41090VF Stage v sporulation protein ac FOC75_RS28025 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC75_RS28040 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOC75_RS28080 ENOG41086D8 Transcriptional regulator FOC75_RS28100 ENOG4108W2Y isochorismatase FOC75_RS28110 ENOG4108NHD germination protein FOC75_RS28130 ENOG4107XGZ Hydrolase FOC75_RS28140 ENOG4105YWU small acid-soluble spore protein FOC75_RS28160 ENOG4107A6P FOC75_RS28170 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS28190 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC75_RS28195 ENOG41089BK Glutamine amido-transferase FOC75_RS28205 ENOG4106J6E FOC75_RS28240 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC75_RS28325 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS28395 ENOG4105TQK DNA polymerase iii, delta' subunit FOC75_RS28405 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC75_RS28420 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS28475 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS28545 ENOG4105EKQ RNA-directed DNA polymerase FOC75_RS28565 ENOG4105K4H Nlp p60 protein FOC75_RS28600 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC75_RS28700 ENOG4105D7V transposase FOC75_RS28845 ENOG41067QW Transcriptional regulator FOC75_RS28875 ENOG4105C6E dna polymerase iii FOC75_RS28885 ENOG4105ENA helicase FOC75_RS28890 ENOG4105FA2 dna polymerase iii FOC75_RS28910 ENOG4108TF4 von Willebrand factor, type A FOC75_RS28915 ENOG4105KRN Transcriptional regulator, abrb family FOC75_RS28985 ENOG4105D6J arsenicaL-resistance protein FOC75_RS28990 ENOG41082YX Transcriptional regulator, arsr family FOC75_RS29005 ENOG4105CKI cobalamin synthesis protein FOC75_RS29010 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC75_RS29020 ENOG41067QW Transcriptional regulator FOC75_RS29025 ENOG4105CJ3 phosphate transporter FOC75_RS29030 ENOG41085FC arsR family transcriptional regulator FOC75_RS29045 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes FOC75_RS29085 ENOG4105C59 p-type ATPase FOC75_RS29090 ENOG4105VPX protein, conserved in bacteria FOC75_RS29095 ENOG4105DSE periplasmic solute binding protein FOC75_RS29125 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding