locus-tag	class	description
FOC75_RS00055	COG4653	Phage capsid family
FOC75_RS00060	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FOC75_RS00065	COG2369	cell adhesion
FOC75_RS00070	COG5518	Phage portal protein
FOC75_RS00080	COG5484	DNA packaging
FOC75_RS00110	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FOC75_RS00210	COG0305	Participates in initiation and elongation during chromosome replication
FOC75_RS00230	COG3723	Recombinational DNA repair protein, rece pathway
FOC75_RS00235	COG5377	YqaJ viral recombinase family
FOC75_RS00260	COG1396	sequence-specific DNA binding
FOC75_RS00295	COG1192	Involved in chromosome partitioning
FOC75_RS00335	COG0322	excinuclease ABC activity
FOC75_RS00350	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS00395	COG1228	amidohydrolase
FOC75_RS00400	COG1090	epimerase
FOC75_RS00430	COG1988	membrane-bound metal-dependent
FOC75_RS00435	COG1194	a g-specific adenine glycosylase
FOC75_RS00460	COG1132	(ABC) transporter
FOC75_RS00465	COG4129	membrane
FOC75_RS00470	COG0067	glutamate synthase
FOC75_RS00470	COG0069	glutamate synthase activity
FOC75_RS00470	COG0070	glutamate synthase
FOC75_RS00480	COG4555	ABC transporter
FOC75_RS00500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC75_RS00505	COG0735	belongs to the Fur family
FOC75_RS00620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC75_RS00625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOC75_RS00635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC75_RS00645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOC75_RS00655	COG2766	serine protein kinase
FOC75_RS00685	COG1396	sequence-specific DNA binding
FOC75_RS00720	COG0305	Participates in initiation and elongation during chromosome replication
FOC75_RS00745	COG0756	dUTP diphosphatase activity
FOC75_RS00790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC75_RS00795	COG0582	viral genome integration into host DNA
FOC75_RS00820	COG4626	Terminase
FOC75_RS00820	COG1802	Transcriptional regulator
FOC75_RS00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOC75_RS00950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC75_RS00960	COG1585	Membrane protein implicated in regulation of membrane protease activity
FOC75_RS00965	COG2268	Band 7 protein
FOC75_RS00975	COG3290	protein histidine kinase activity
FOC75_RS00980	COG4565	transcriptional regulatory protein
FOC75_RS00985	COG2851	Citrate transporter
FOC75_RS01005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC75_RS01010	COG3842	ATPase activity
FOC75_RS01015	COG1175	transmembrane transport
FOC75_RS01020	COG0395	ABC-type sugar transport system, permease component
FOC75_RS01030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOC75_RS01035	COG0745	RESPONSE REGULATOR receiver
FOC75_RS01040	COG5002	protein histidine kinase activity
FOC75_RS01050	COG4990	cell redox homeostasis
FOC75_RS01060	COG3290	protein histidine kinase activity
FOC75_RS01065	COG4565	transcriptional regulatory protein
FOC75_RS01070	COG3493	citrate carrier protein
FOC75_RS01075	COG0281	malic enzyme
FOC75_RS01090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS01100	COG5002	protein histidine kinase activity
FOC75_RS01105	COG0745	RESPONSE REGULATOR receiver
FOC75_RS01110	COG0454	-acetyltransferase
FOC75_RS01110	COG0456	acetyltransferase
FOC75_RS01115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC75_RS01120	COG3383	formate dehydrogenase (NAD+) activity
FOC75_RS01125	COG2427	Protein of unknown function (DUF1641)
FOC75_RS01140	COG0531	amino acid
FOC75_RS01145	COG0640	Transcriptional regulator
FOC75_RS01150	COG2217	Heavy metal translocating P-type atpase
FOC75_RS01155	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC75_RS01170	COG3227	Zinc metalloprotease (Elastase)
FOC75_RS01190	COG2720	vancomycin resistance protein
FOC75_RS01195	COG1316	TRANSCRIPTIONal
FOC75_RS01200	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS01205	COG0346	lactoylglutathione lyase activity
FOC75_RS01210	COG1253	flavin adenine dinucleotide binding
FOC75_RS01215	COG1027	Aspartate ammonia-lyase
FOC75_RS01220	COG1620	l-lactate permease
FOC75_RS01235	COG3104	oligopeptide transport
FOC75_RS01240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS01245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS01250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS01265	COG0156	8-amino-7-oxononanoate synthase activity
FOC75_RS01270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC75_RS01280	COG4548	von Willebrand factor, type A
FOC75_RS01285	COG0714	Associated with various cellular activities
FOC75_RS01290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC75_RS01310	COG0531	amino acid
FOC75_RS01315	COG2188	Transcriptional regulator
FOC75_RS01320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC75_RS01320	COG1263	PTS System
FOC75_RS01325	COG0366	Alpha amylase catalytic
FOC75_RS01340	COG0697	spore germination
FOC75_RS01350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC75_RS01355	COG1115	amino acid carrier protein
FOC75_RS01360	COG1126	abc transporter atp-binding protein
FOC75_RS01365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC75_RS01370	COG0765	amino acid transport
FOC75_RS01375	COG0765	amino acid transport
FOC75_RS01380	COG0833	amino acid
FOC75_RS01395	COG1595	DNA-templated transcription, initiation
FOC75_RS01405	COG2378	regulation of single-species biofilm formation
FOC75_RS01410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FOC75_RS01415	COG5002	protein histidine kinase activity
FOC75_RS01430	COG0659	secondary active sulfate transmembrane transporter activity
FOC75_RS01445	COG0747	negative chemotaxis
FOC75_RS01455	COG0601	transmembrane transport
FOC75_RS01460	COG4608	Belongs to the ABC transporter superfamily
FOC75_RS01470	COG2271	Major facilitator Superfamily
FOC75_RS01475	COG1846	Transcriptional regulator
FOC75_RS01480	COG0477	Major facilitator Superfamily
FOC75_RS01485	COG1609	Transcriptional regulator
FOC75_RS01490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC75_RS01505	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC75_RS01510	COG1879	ABC-type sugar transport system periplasmic component
FOC75_RS01530	COG1063	alcohol dehydrogenase
FOC75_RS01545	COG3568	Endonuclease Exonuclease Phosphatase
FOC75_RS01575	COG0840	transmembrane signaling receptor activity
FOC75_RS01580	COG3583	domain protein
FOC75_RS01580	COG3584	3D domain protein
FOC75_RS01585	COG1476	TRANSCRIPTIONal
FOC75_RS01600	COG3104	oligopeptide transport
FOC75_RS01605	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS01620	COG1113	amino acid transport
FOC75_RS01625	COG2252	PERMEase
FOC75_RS01640	COG2153	protein acetylation
FOC75_RS01650	COG0569	domain protein
FOC75_RS01650	COG0475	glutathione-regulated potassium exporter activity
FOC75_RS01665	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOC75_RS01670	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOC75_RS01675	COG0833	amino acid
FOC75_RS01680	COG4990	cell redox homeostasis
FOC75_RS01695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC75_RS01700	COG0697	spore germination
FOC75_RS01705	COG0531	amino acid
FOC75_RS01715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC75_RS01720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC75_RS01725	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC75_RS01725	COG1918	ferrous iron import across plasma membrane
FOC75_RS01730	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC75_RS01735	COG0573	inorganic phosphate transmembrane transporter activity
FOC75_RS01740	COG0581	inorganic phosphate transmembrane transporter activity
FOC75_RS01745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC75_RS01865	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FOC75_RS01885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC75_RS01890	COG1116	anion transmembrane transporter activity
FOC75_RS01895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC75_RS01900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC75_RS01905	COG0352	thiamine-phosphate diphosphorylase activity
FOC75_RS01910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC75_RS01915	COG2104	thiamine diphosphate biosynthetic process
FOC75_RS01925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC75_RS01930	COG0351	phosphomethylpyrimidine kinase
FOC75_RS01970	COG2205	protein histidine kinase activity
FOC75_RS01975	COG2814	Major facilitator Superfamily
FOC75_RS01980	COG1846	Transcriptional regulator
FOC75_RS01995	COG2252	PERMEase
FOC75_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS02005	COG1376	ErfK ybiS ycfS ynhG family protein
FOC75_RS02020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC75_RS02060	COG0778	Nitroreductase
FOC75_RS02065	COG2719	SpoVR family
FOC75_RS02075	COG3591	Belongs to the peptidase S1B family
FOC75_RS02085	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC75_RS02090	COG1937	Protein conserved in bacteria
FOC75_RS02095	COG0425	Belongs to the sulfur carrier protein TusA family
FOC75_RS02095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC75_RS02100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS02100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC75_RS02105	COG0425	Belongs to the sulfur carrier protein TusA family
FOC75_RS02110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC75_RS02120	COG2210	Belongs to the sulfur carrier protein TusA family
FOC75_RS02125	COG0730	response to heat
FOC75_RS02135	COG1316	TRANSCRIPTIONal
FOC75_RS02140	COG0604	alcohol dehydrogenase
FOC75_RS02145	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC75_RS02160	COG3711	transcriptional antiterminator
FOC75_RS02160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC75_RS02165	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC75_RS02170	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC75_RS02190	COG1388	LysM domain
FOC75_RS02190	COG3584	3D domain protein
FOC75_RS02195	COG0577	efflux transmembrane transporter activity
FOC75_RS02200	COG1136	(ABC) transporter
FOC75_RS02210	COG5522	Integral membrane protein (intg_mem_TP0381)
FOC75_RS02225	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS02230	COG3546	catalase activity
FOC75_RS02265	COG0586	Pfam SNARE associated Golgi protein
FOC75_RS02300	COG0531	amino acid
FOC75_RS02305	COG0475	glutathione-regulated potassium exporter activity
FOC75_RS02315	COG1737	Transcriptional regulator
FOC75_RS02325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC75_RS02325	COG1263	PTS System
FOC75_RS02335	COG2259	Doxx family
FOC75_RS02355	COG1522	sequence-specific DNA binding
FOC75_RS02370	COG2076	Multidrug Resistance protein
FOC75_RS02375	COG1309	transcriptional regulator
FOC75_RS02380	COG2814	Major facilitator Superfamily
FOC75_RS02385	COG1733	regulation of RNA biosynthetic process
FOC75_RS02395	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC75_RS02405	COG4533	DNA binding
FOC75_RS02410	COG2211	Major facilitator Superfamily
FOC75_RS02420	COG0693	protein deglycase activity
FOC75_RS02425	COG0753	catalase activity
FOC75_RS02425	COG0693	protein deglycase activity
FOC75_RS02435	COG0531	amino acid
FOC75_RS02440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC75_RS02450	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS02455	COG1132	(ABC) transporter
FOC75_RS02460	COG1132	(ABC) transporter
FOC75_RS02465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC75_RS02470	COG0765	amino acid transport
FOC75_RS02475	COG1126	abc transporter atp-binding protein
FOC75_RS02490	COG0189	ligase activity
FOC75_RS02520	COG0028	Belongs to the TPP enzyme family
FOC75_RS02525	COG3527	Alpha-acetolactate decarboxylase
FOC75_RS02535	COG0561	phosphatase activity
FOC75_RS02545	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS02545	COG3409	Peptidoglycan-binding domain 1 protein
FOC75_RS02550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC75_RS02565	COG0659	secondary active sulfate transmembrane transporter activity
FOC75_RS02585	COG0653	protein targeting
FOC75_RS02590	COG2244	polysaccharide biosynthetic process
FOC75_RS02600	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS02620	COG1696	Membrane protein involved in D-alanine export
FOC75_RS02635	COG1024	Enoyl-CoA hydratase
FOC75_RS02655	COG1363	Peptidase, m42
FOC75_RS02675	COG3938	Belongs to the proline racemase family
FOC75_RS02715	COG0601	transmembrane transport
FOC75_RS02720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC75_RS02725	COG0444	Belongs to the ABC transporter superfamily
FOC75_RS02730	COG4608	Belongs to the ABC transporter superfamily
FOC75_RS02745	COG0477	Major facilitator Superfamily
FOC75_RS02750	COG3290	protein histidine kinase activity
FOC75_RS02755	COG4565	transcriptional regulatory protein
FOC75_RS02760	COG3181	Tripartite tricarboxylate transporter family receptor
FOC75_RS02765	COG0494	nUDIX hydrolase
FOC75_RS02825	COG0305	Participates in initiation and elongation during chromosome replication
FOC75_RS02845	COG0477	Major facilitator Superfamily
FOC75_RS02920	COG1183	phosphatidylcholine synthase activity
FOC75_RS02950	COG2376	Dihydroxyacetone kinase
FOC75_RS02960	COG2376	Dihydroxyacetone kinase
FOC75_RS02975	COG3437	response regulator, receiver
FOC75_RS02975	COG2770	Histidine kinase
FOC75_RS03025	COG3237	CsbD-like
FOC75_RS03050	COG1191	sigma factor activity
FOC75_RS03060	COG2208	phosphoserine phosphatase activity
FOC75_RS03065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC75_RS03070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC75_RS03070	COG2198	Histidine kinase
FOC75_RS03070	COG0784	Response regulator, receiver
FOC75_RS03070	COG2205	protein histidine kinase activity
FOC75_RS03130	COG0420	3'-5' exonuclease activity
FOC75_RS03135	COG4717	serine-type aminopeptidase activity
FOC75_RS03155	COG5444	nuclease activity
FOC75_RS03170	COG0346	lactoylglutathione lyase activity
FOC75_RS03175	COG0346	lactoylglutathione lyase activity
FOC75_RS03180	COG0457	Tetratricopeptide repeat
FOC75_RS03190	COG2267	carboxylic ester hydrolase activity
FOC75_RS03210	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FOC75_RS03215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC75_RS03225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FOC75_RS03250	COG0772	Belongs to the SEDS family
FOC75_RS03265	COG0477	Major facilitator Superfamily
FOC75_RS03270	COG0477	Major facilitator Superfamily
FOC75_RS03280	COG3973	AAA domain
FOC75_RS03285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC75_RS03305	COG4980	gas vesicle protein
FOC75_RS03310	COG0537	adenosine 5'-monophosphoramidase activity
FOC75_RS03315	COG1131	(ABC) transporter
FOC75_RS03320	COG4473	ABC transporter
FOC75_RS03375	COG1309	transcriptional regulator
FOC75_RS03385	COG3402	PFAM membrane-flanked domain
FOC75_RS03390	COG3428	Bacterial PH domain
FOC75_RS03430	COG3402	PFAM membrane-flanked domain
FOC75_RS03435	COG3428	Bacterial PH domain
FOC75_RS03440	COG2329	Antibiotic biosynthesis monooxygenase
FOC75_RS03445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC75_RS03490	COG1309	transcriptional regulator
FOC75_RS03495	COG1511	domain protein
FOC75_RS03515	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FOC75_RS03525	COG2378	regulation of single-species biofilm formation
FOC75_RS03530	COG1609	Transcriptional regulator
FOC75_RS03540	COG1234	tRNA 3'-trailer cleavage
FOC75_RS03545	COG0095	Lipoate-protein ligase
FOC75_RS03555	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS03600	COG3209	COG3209 Rhs family protein
FOC75_RS03615	COG3209	COG3209 Rhs family protein
FOC75_RS03655	COG1408	metallophosphoesterase
FOC75_RS03665	COG1078	dGTPase activity
FOC75_RS03675	COG1595	DNA-templated transcription, initiation
FOC75_RS03680	COG3708	Transcriptional regulator
FOC75_RS03680	COG2207	Transcriptional regulator
FOC75_RS03695	COG2205	protein histidine kinase activity
FOC75_RS03700	COG0745	RESPONSE REGULATOR receiver
FOC75_RS03725	COG0501	Belongs to the peptidase M48B family
FOC75_RS03730	COG0697	spore germination
FOC75_RS03750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOC75_RS03755	COG2224	Isocitrate lyase
FOC75_RS03780	COG4903	ComK protein
FOC75_RS03785	COG0398	Pfam SNARE associated Golgi protein
FOC75_RS03845	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC75_RS03870	COG0367	asparagine synthase
FOC75_RS03880	COG0753	catalase activity
FOC75_RS03885	COG0004	ammonium transporteR
FOC75_RS03905	COG2996	Protein conserved in bacteria
FOC75_RS03915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC75_RS03925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS03940	COG0561	phosphatase activity
FOC75_RS03950	COG0542	response to heat
FOC75_RS03960	COG2267	carboxylic ester hydrolase activity
FOC75_RS03975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS03980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC75_RS03985	COG5504	Zn-dependent protease
FOC75_RS03995	COG0180	Tryptophanyl-tRNA synthetase
FOC75_RS04005	COG4166	transmembrane transport
FOC75_RS04010	COG0601	transmembrane transport
FOC75_RS04015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC75_RS04020	COG0444	Belongs to the ABC transporter superfamily
FOC75_RS04025	COG4608	Belongs to the ABC transporter superfamily
FOC75_RS04030	COG0534	Mate efflux family protein
FOC75_RS04035	COG4166	transmembrane transport
FOC75_RS04050	COG0861	Integral membrane protein TerC family
FOC75_RS04055	COG4862	establishment of competence for transformation
FOC75_RS04060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC75_RS04070	COG1164	Oligoendopeptidase f
FOC75_RS04085	COG2346	COG2346, Truncated hemoglobins
FOC75_RS04090	COG4116	CYTH
FOC75_RS04100	COG2357	RelA SpoT domain protein
FOC75_RS04110	COG0564	pseudouridine synthase activity
FOC75_RS04125	COG0772	Belongs to the SEDS family
FOC75_RS04130	COG0463	Glycosyl transferase, family 2
FOC75_RS04130	COG1216	Glycosyl transferase, family 2
FOC75_RS04150	COG0457	Tetratricopeptide repeat
FOC75_RS04150	COG0463	Glycosyl transferase, family 2
FOC75_RS04170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC75_RS04185	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC75_RS04230	COG2153	protein acetylation
FOC75_RS04240	COG2382	esterase
FOC75_RS04255	COG5492	domain, Protein
FOC75_RS04260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC75_RS04270	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC75_RS04270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC75_RS04305	COG1620	l-lactate permease
FOC75_RS04310	COG5634	Uncharacterized conserved protein (DUF2278)
FOC75_RS04375	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC75_RS04385	COG1476	TRANSCRIPTIONal
FOC75_RS04520	COG4695	Portal protein
FOC75_RS04540	COG4974	Belongs to the 'phage' integrase family
FOC75_RS04555	COG2226	methyltransferase
FOC75_RS04565	COG1686	Belongs to the peptidase S11 family
FOC75_RS04570	COG0681	Belongs to the peptidase S26 family
FOC75_RS04605	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS04615	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC75_RS04620	COG1177	transmembrane transport
FOC75_RS04625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FOC75_RS04635	COG2409	Drug exporters of the RND superfamily
FOC75_RS04645	COG0564	pseudouridine synthase activity
FOC75_RS04655	COG2340	Cysteine-rich secretory protein family
FOC75_RS04660	COG0247	lactate metabolic process
FOC75_RS04665	COG0277	FAD linked oxidase domain protein
FOC75_RS04670	COG3835	regulator
FOC75_RS04680	COG0745	RESPONSE REGULATOR receiver
FOC75_RS04685	COG5002	protein histidine kinase activity
FOC75_RS04690	COG2186	Transcriptional regulator
FOC75_RS04710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOC75_RS04720	COG2116	formate transmembrane transporter activity
FOC75_RS04725	COG0861	Integral membrane protein TerC family
FOC75_RS04730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC75_RS04740	COG2030	dehydratase
FOC75_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS04765	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOC75_RS04775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC75_RS04790	COG1840	ABC-type Fe3 transport system, periplasmic component
FOC75_RS04795	COG3842	ATPase activity
FOC75_RS04820	COG1349	DNA-binding transcription factor activity
FOC75_RS04830	COG0235	Class ii aldolase
FOC75_RS04840	COG2861	carbohydrate metabolic process
FOC75_RS04850	COG3852	Histidine kinase
FOC75_RS04855	COG1846	Transcriptional regulator
FOC75_RS04865	COG2318	DinB family
FOC75_RS04870	COG5002	protein histidine kinase activity
FOC75_RS04880	COG0720	synthase
FOC75_RS04895	COG4873	Protein conserved in bacteria
FOC75_RS04925	COG1780	Probably involved in ribonucleotide reductase function
FOC75_RS04945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC75_RS04950	COG1725	Transcriptional regulator
FOC75_RS04955	COG1131	(ABC) transporter
FOC75_RS04965	COG1131	(ABC) transporter
FOC75_RS04970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC75_RS04975	COG1266	CAAX protease self-immunity
FOC75_RS04985	COG1522	sequence-specific DNA binding
FOC75_RS04995	COG1335	isochorismatase
FOC75_RS05005	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC75_RS05010	COG2070	2-Nitropropane dioxygenase
FOC75_RS05015	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC75_RS05025	COG1696	Membrane protein involved in D-alanine export
FOC75_RS05050	COG0716	FMN binding
FOC75_RS05085	COG0534	Mate efflux family protein
FOC75_RS05090	COG1968	undecaprenyl-diphosphatase activity
FOC75_RS05105	COG1846	Transcriptional regulator
FOC75_RS05115	COG1301	dicarboxylic acid transport
FOC75_RS05120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC75_RS05125	COG4709	membrane
FOC75_RS05130	COG3874	Sporulation protein YtfJ
FOC75_RS05150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC75_RS05155	COG0028	Belongs to the TPP enzyme family
FOC75_RS05160	COG0440	acetolactate synthase activity
FOC75_RS05235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC75_RS05250	COG1183	phosphatidylcholine synthase activity
FOC75_RS05255	COG1368	sulfuric ester hydrolase activity
FOC75_RS05265	COG0019	diaminopimelate decarboxylase activity
FOC75_RS05285	COG0529	Catalyzes the synthesis of activated sulfate
FOC75_RS05290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC75_RS05310	COG1648	precorrin-2 dehydrogenase activity
FOC75_RS05315	COG0733	neurotransmitter:sodium symporter activity
FOC75_RS05335	COG1757	Na H antiporter
FOC75_RS05350	COG4758	membrane
FOC75_RS05355	COG4585	Histidine kinase
FOC75_RS05360	COG2197	response regulator
FOC75_RS05370	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS05380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOC75_RS05420	COG0730	response to heat
FOC75_RS05425	COG0306	phosphate transporter
FOC75_RS05430	COG1392	Phosphate transport regulator
FOC75_RS05435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC75_RS05450	COG3852	Histidine kinase
FOC75_RS05455	COG1801	Protein of unknown function DUF72
FOC75_RS05465	COG0582	viral genome integration into host DNA
FOC75_RS05470	COG5002	protein histidine kinase activity
FOC75_RS05490	COG0392	lysyltransferase activity
FOC75_RS05490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FOC75_RS05505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC75_RS05510	COG1686	Belongs to the peptidase S11 family
FOC75_RS05515	COG2715	membrane protein required for spore maturation
FOC75_RS05520	COG0700	Nucleoside recognition
FOC75_RS05525	COG1187	pseudouridine synthase activity
FOC75_RS05535	COG1333	cytochrome c biogenesis protein
FOC75_RS05540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC75_RS05545	COG0745	RESPONSE REGULATOR receiver
FOC75_RS05550	COG5002	protein histidine kinase activity
FOC75_RS05555	COG2096	Adenosyltransferase
FOC75_RS05560	COG4942	peptidase
FOC75_RS05570	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FOC75_RS05575	COG1141	Ferredoxin
FOC75_RS05585	COG0514	ATP-dependent DNA helicase (RecQ)
FOC75_RS05590	COG1266	CAAX protease self-immunity
FOC75_RS05600	COG1408	metallophosphoesterase
FOC75_RS05610	COG4862	establishment of competence for transformation
FOC75_RS05615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC75_RS05635	COG0492	ferredoxin-NADP+ reductase activity
FOC75_RS05710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC75_RS05725	COG0142	geranyltranstransferase activity
FOC75_RS05735	COG0142	geranyltranstransferase activity
FOC75_RS05755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC75_RS05760	COG0457	Tetratricopeptide repeat
FOC75_RS05780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOC75_RS05790	COG4347	Protein of unknown function (DUF1405)
FOC75_RS05805	COG2738	Putative neutral zinc metallopeptidase
FOC75_RS05815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS05820	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC75_RS05835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC75_RS05840	COG0438	transferase activity, transferring glycosyl groups
FOC75_RS05875	COG1199	ATP-dependent helicase activity
FOC75_RS05875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOC75_RS05895	COG3935	DnaD domain protein
FOC75_RS05900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOC75_RS05910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC75_RS05910	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC75_RS05970	COG0116	Belongs to the methyltransferase superfamily
FOC75_RS05980	COG1199	ATP-dependent helicase activity
FOC75_RS05985	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FOC75_RS05995	COG3173	Aminoglycoside phosphotransferase
FOC75_RS06000	COG0024	Methionine aminopeptidase
FOC75_RS06010	COG2233	PERMEase
FOC75_RS06015	COG2311	Membrane
FOC75_RS06020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC75_RS06030	COG0456	acetyltransferase
FOC75_RS06065	COG0754	glutathionylspermidine amidase activity
FOC75_RS06080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC75_RS06105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC75_RS06120	COG1215	transferase activity, transferring glycosyl groups
FOC75_RS06125	COG0438	transferase activity, transferring glycosyl groups
FOC75_RS06140	COG0454	-acetyltransferase
FOC75_RS06160	COG0328	RNA-DNA hybrid ribonuclease activity
FOC75_RS06195	COG3403	YqcI/YcgG family
FOC75_RS06200	COG1280	lysine exporter protein (LysE YggA)
FOC75_RS06215	COG3162	membrane
FOC75_RS06220	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC75_RS06225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC75_RS06235	COG0475	glutathione-regulated potassium exporter activity
FOC75_RS06240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC75_RS06245	COG0789	Transcriptional regulator
FOC75_RS06245	COG4978	Transcriptional regulator
FOC75_RS06255	COG2323	membrane
FOC75_RS06260	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FOC75_RS06315	COG1923	regulation of RNA biosynthetic process
FOC75_RS06325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC75_RS06330	COG1360	Flagellar Motor Protein
FOC75_RS06335	COG2201	protein-glutamate methylesterase activity
FOC75_RS06340	COG2198	Histidine kinase
FOC75_RS06340	COG0643	Histidine kinase
FOC75_RS06345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC75_RS06345	COG1776	CheC inhibitor of MCP methylation
FOC75_RS06360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOC75_RS06380	COG1256	bacterial-type flagellum assembly
FOC75_RS06385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC75_RS06390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOC75_RS06405	COG1815	bacterial-type flagellum-dependent cell motility
FOC75_RS06410	COG1558	bacterial-type flagellum-dependent cell motility
FOC75_RS06420	COG1766	The M ring may be actively involved in energy transduction
FOC75_RS06425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC75_RS06435	COG1157	protein secretion by the type III secretion system
FOC75_RS06470	COG0784	Response regulator, receiver
FOC75_RS06470	COG0835	chemotaxis
FOC75_RS06480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC75_RS06485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FOC75_RS06490	COG0741	lytic transglycosylase activity
FOC75_RS06500	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC75_RS06505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOC75_RS06505	COG1776	CheC inhibitor of MCP methylation
FOC75_RS06515	COG1338	Plays a role in the flagellum-specific transport system
FOC75_RS06520	COG1987	bacterial-type flagellum assembly
FOC75_RS06530	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC75_RS06535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOC75_RS06540	COG1419	protein localization to endoplasmic reticulum
FOC75_RS06545	COG4786	Flagellar basal body rod
FOC75_RS06550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC75_RS06585	COG2329	Antibiotic biosynthesis monooxygenase
FOC75_RS06610	COG0583	DNA-binding transcription factor activity
FOC75_RS06615	COG3842	ATPase activity
FOC75_RS06630	COG1234	tRNA 3'-trailer cleavage
FOC75_RS06660	COG1686	Belongs to the peptidase S11 family
FOC75_RS06670	COG0406	alpha-ribazole phosphatase activity
FOC75_RS06690	COG1846	Transcriptional regulator
FOC75_RS06700	COG0367	asparagine synthase
FOC75_RS06730	COG1802	Transcriptional regulator
FOC75_RS06735	COG0697	spore germination
FOC75_RS06740	COG0523	cobalamin synthesis protein
FOC75_RS06745	COG0701	Predicted permease
FOC75_RS06755	COG0438	transferase activity, transferring glycosyl groups
FOC75_RS06755	COG1216	Glycosyl transferase, family 2
FOC75_RS06760	COG1757	Na H antiporter
FOC75_RS06765	COG0789	Transcriptional regulator
FOC75_RS06775	COG0114	fumarate hydratase activity
FOC75_RS06795	COG0534	Mate efflux family protein
FOC75_RS06800	COG3340	Belongs to the peptidase S51 family
FOC75_RS06820	COG0785	Cytochrome C biogenesis protein
FOC75_RS06850	COG2733	membrane
FOC75_RS06885	COG1131	(ABC) transporter
FOC75_RS06900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC75_RS06905	COG0528	UMP kinase activity
FOC75_RS06915	COG1027	Aspartate ammonia-lyase
FOC75_RS06920	COG0281	malic enzyme
FOC75_RS06925	COG4191	Histidine kinase
FOC75_RS06930	COG0784	Response regulator, receiver
FOC75_RS06935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC75_RS06990	COG1051	belongs to the nudix hydrolase family
FOC75_RS06995	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS07005	COG2814	Major facilitator Superfamily
FOC75_RS07020	COG1966	Carbon starvation protein
FOC75_RS07030	COG0477	Major facilitator Superfamily
FOC75_RS07035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS07045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC75_RS07050	COG4166	transmembrane transport
FOC75_RS07055	COG2223	nitrite transmembrane transporter activity
FOC75_RS07060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC75_RS07075	COG2244	polysaccharide biosynthetic process
FOC75_RS07080	COG0733	neurotransmitter:sodium symporter activity
FOC75_RS07090	COG5566	PFAM Mor transcription activator
FOC75_RS07095	COG2323	membrane
FOC75_RS07110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC75_RS07120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC75_RS07125	COG0028	Belongs to the TPP enzyme family
FOC75_RS07130	COG0440	acetolactate synthase activity
FOC75_RS07135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC75_RS07145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOC75_RS07170	COG2814	Major facilitator Superfamily
FOC75_RS07175	COG3384	dioxygenase
FOC75_RS07185	COG3279	Response regulator of the LytR AlgR family
FOC75_RS07190	COG0427	acetyl-CoA hydrolase
FOC75_RS07210	COG4166	transmembrane transport
FOC75_RS07240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS07260	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC75_RS07275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC75_RS07280	COG0531	amino acid
FOC75_RS07305	COG2390	Transcriptional regulator
FOC75_RS07315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS07320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOC75_RS07330	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC75_RS07355	COG0006	proline dipeptidase activity
FOC75_RS07360	COG2132	Multicopper oxidase
FOC75_RS07390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC75_RS07395	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS07405	COG2372	response to copper ion
FOC75_RS07405	COG1276	copper resistance
FOC75_RS07410	COG4549	nuclear export factor GLE1
FOC75_RS07415	COG0697	spore germination
FOC75_RS07420	COG0583	DNA-binding transcription factor activity
FOC75_RS07425	COG1959	2 iron, 2 sulfur cluster binding
FOC75_RS07430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC75_RS07435	COG0778	Nitroreductase
FOC75_RS07450	COG0628	permease
FOC75_RS07460	COG1231	oxidoreductase activity
FOC75_RS07465	COG0523	cobalamin synthesis protein
FOC75_RS07480	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS07485	COG2030	dehydratase
FOC75_RS07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS07500	COG0411	ABC transporter
FOC75_RS07520	COG0583	DNA-binding transcription factor activity
FOC75_RS07550	COG1271	oxidase subunit
FOC75_RS07555	COG1294	oxidase, subunit
FOC75_RS07560	COG4988	ABC transporter
FOC75_RS07565	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOC75_RS07585	COG1686	Belongs to the peptidase S11 family
FOC75_RS07600	COG1388	LysM domain
FOC75_RS07600	COG0791	NLP P60 protein
FOC75_RS07610	COG1132	(ABC) transporter
FOC75_RS07615	COG0745	RESPONSE REGULATOR receiver
FOC75_RS07620	COG5002	protein histidine kinase activity
FOC75_RS07630	COG0300	oxidoreductase activity
FOC75_RS07650	COG5658	integral membrane protein
FOC75_RS07665	COG0460	homoserine dehydrogenase
FOC75_RS07690	COG1316	TRANSCRIPTIONal
FOC75_RS07700	COG0745	RESPONSE REGULATOR receiver
FOC75_RS07705	COG5002	protein histidine kinase activity
FOC75_RS07720	COG1285	pathogenesis
FOC75_RS07725	COG1247	-acetyltransferase
FOC75_RS07735	COG4264	IucA IucC family
FOC75_RS07740	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS07755	COG1082	Xylose isomerase domain protein TIM barrel
FOC75_RS07765	COG2814	Major facilitator Superfamily
FOC75_RS07770	COG1279	arginine transmembrane transporter activity
FOC75_RS07780	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC75_RS07815	COG0577	efflux transmembrane transporter activity
FOC75_RS07820	COG2002	toxin-antitoxin pair type II binding
FOC75_RS07825	COG1404	Belongs to the peptidase S8 family
FOC75_RS07830	COG0640	Transcriptional regulator
FOC75_RS07835	COG0667	Aldo Keto reductase
FOC75_RS07840	COG2814	Major facilitator Superfamily
FOC75_RS07865	COG0840	transmembrane signaling receptor activity
FOC75_RS07880	COG3949	Membrane
FOC75_RS07885	COG0783	Belongs to the Dps family
FOC75_RS07900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC75_RS07910	COG1231	oxidoreductase activity
FOC75_RS07920	COG4989	oxidoreductase activity
FOC75_RS07925	COG0523	cobalamin synthesis protein
FOC75_RS07930	COG0456	acetyltransferase
FOC75_RS07985	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC75_RS07985	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC75_RS07995	COG0702	epimerase
FOC75_RS08005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC75_RS08015	COG4166	transmembrane transport
FOC75_RS08030	COG0406	alpha-ribazole phosphatase activity
FOC75_RS08040	COG5337	Spore coat protein CotH
FOC75_RS08045	COG1051	belongs to the nudix hydrolase family
FOC75_RS08050	COG0586	Pfam SNARE associated Golgi protein
FOC75_RS08055	COG2244	polysaccharide biosynthetic process
FOC75_RS08065	COG0701	Predicted permease
FOC75_RS08070	COG3689	TIGRFAM TIGR03943 family protein
FOC75_RS08075	COG1607	acyl-coa hydrolase
FOC75_RS08085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC75_RS08100	COG0702	epimerase
FOC75_RS08105	COG2839	Protein conserved in bacteria
FOC75_RS08110	COG1253	flavin adenine dinucleotide binding
FOC75_RS08125	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS08130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC75_RS08150	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS08160	COG1876	peptidase activity
FOC75_RS08170	COG0154	amidase activity
FOC75_RS08175	COG2211	Major facilitator Superfamily
FOC75_RS08195	COG0561	phosphatase activity
FOC75_RS08205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC75_RS08210	COG4106	trans-aconitate 2-methyltransferase activity
FOC75_RS08225	COG1819	glycosyl
FOC75_RS08230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS08235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS08265	COG0456	acetyltransferase
FOC75_RS08325	COG3344	reverse transcriptase
FOC75_RS08335	COG3874	Sporulation protein YtfJ
FOC75_RS08360	COG2226	methyltransferase
FOC75_RS08385	COG0346	lactoylglutathione lyase activity
FOC75_RS08395	COG0604	alcohol dehydrogenase
FOC75_RS08400	COG1595	DNA-templated transcription, initiation
FOC75_RS08415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOC75_RS08435	COG0386	Belongs to the glutathione peroxidase family
FOC75_RS08440	COG1305	Transglutaminase-like
FOC75_RS08445	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FOC75_RS08450	COG0714	Associated with various cellular activities
FOC75_RS08455	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FOC75_RS08460	COG1140	nitrate reductase beta subunit
FOC75_RS08465	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FOC75_RS08470	COG2181	nitrate reductase activity
FOC75_RS08480	COG1959	2 iron, 2 sulfur cluster binding
FOC75_RS08485	COG3118	belongs to the thioredoxin family
FOC75_RS08490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC75_RS08495	COG4918	Iron-sulphur cluster biosynthesis
FOC75_RS08500	COG1764	response to oxidative stress
FOC75_RS08505	COG1335	isochorismatase
FOC75_RS08515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC75_RS08520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC75_RS08525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC75_RS08530	COG0303	'Molybdopterin
FOC75_RS08535	COG0314	molybdopterin synthase activity
FOC75_RS08545	COG2223	nitrite transmembrane transporter activity
FOC75_RS08555	COG1648	precorrin-2 dehydrogenase activity
FOC75_RS08565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOC75_RS08565	COG1587	Uroporphyrinogen-III synthase
FOC75_RS08570	COG2146	nitrite reductase [NAD(P)H] activity
FOC75_RS08575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOC75_RS08580	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC75_RS08615	COG2359	stage V sporulation protein S
FOC75_RS08640	COG1418	mRNA catabolic process
FOC75_RS08645	COG0488	(ABC) transporter
FOC75_RS08660	COG0629	single-stranded DNA binding
FOC75_RS08665	COG3344	reverse transcriptase
FOC75_RS08670	COG1413	lyase activity
FOC75_RS08700	COG0018	arginyl-trna synthetase
FOC75_RS08720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC75_RS08740	COG0017	Asparaginyl-tRNA synthetase
FOC75_RS08760	COG1674	ftsk spoiiie
FOC75_RS08805	COG1929	Belongs to the glycerate kinase type-1 family
FOC75_RS08810	COG0471	metal ion transport
FOC75_RS08815	COG0745	RESPONSE REGULATOR receiver
FOC75_RS08820	COG3850	Histidine kinase
FOC75_RS08820	COG5002	protein histidine kinase activity
FOC75_RS08835	COG0733	neurotransmitter:sodium symporter activity
FOC75_RS08860	COG2610	gluconate transmembrane transporter activity
FOC75_RS08865	COG1454	alcohol dehydrogenase
FOC75_RS08880	COG0456	acetyltransferase
FOC75_RS08885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC75_RS08895	COG1131	(ABC) transporter
FOC75_RS08900	COG4473	ABC transporter
FOC75_RS08910	COG0546	phosphoglycolate phosphatase activity
FOC75_RS08930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC75_RS08945	COG0768	penicillin binding
FOC75_RS08955	COG0204	Acyl-transferase
FOC75_RS08960	COG1272	protein, Hemolysin III
FOC75_RS08970	COG0805	protein transport
FOC75_RS08980	COG1307	EDD domain protein, DegV family
FOC75_RS08985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC75_RS08990	COG1999	signal sequence binding
FOC75_RS08995	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC75_RS09000	COG0367	asparagine synthase
FOC75_RS09015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS09020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC75_RS09040	COG1335	isochorismatase
FOC75_RS09045	COG1051	belongs to the nudix hydrolase family
FOC75_RS09050	COG0071	Belongs to the small heat shock protein (HSP20) family
FOC75_RS09055	COG0668	transmembrane transport
FOC75_RS09060	COG4585	Histidine kinase
FOC75_RS09060	COG2203	Gaf domain
FOC75_RS09065	COG2197	response regulator
FOC75_RS09075	COG1064	alcohol dehydrogenase
FOC75_RS09100	COG1070	Carbohydrate kinase
FOC75_RS09105	COG1070	Carbohydrate kinase
FOC75_RS09135	COG0517	IMP dehydrogenase activity
FOC75_RS09135	COG1125	glycine betaine transport
FOC75_RS09140	COG1174	glycine betaine transport
FOC75_RS09175	COG1253	flavin adenine dinucleotide binding
FOC75_RS09180	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS09185	COG5506	Protein of unknown function (DUF1694)
FOC75_RS09200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC75_RS09205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FOC75_RS09210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOC75_RS09215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC75_RS09220	COG0456	acetyltransferase
FOC75_RS09225	COG3829	transcription factor binding
FOC75_RS09230	COG1509	lysine 2,3-aminomutase activity
FOC75_RS09270	COG4326	sporulation control protein
FOC75_RS09275	COG0671	phosphoesterase, PA-phosphatase related
FOC75_RS09280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC75_RS09285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC75_RS09315	COG1715	Restriction endonuclease
FOC75_RS09315	COG1787	Restriction endonuclease
FOC75_RS09405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC75_RS09445	COG4499	WXG100 protein secretion system (Wss), protein YukC
FOC75_RS09445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC75_RS09455	COG4841	protein insertion into membrane
FOC75_RS09460	COG0372	Belongs to the citrate synthase family
FOC75_RS09465	COG2079	MmgE PrpD family protein
FOC75_RS09470	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOC75_RS09475	COG1960	acyl-CoA dehydrogenase activity
FOC75_RS09480	COG2084	Dehydrogenase
FOC75_RS09490	COG1280	lysine exporter protein (LysE YggA)
FOC75_RS09495	COG1024	Enoyl-CoA hydratase
FOC75_RS09510	COG0420	3'-5' exonuclease activity
FOC75_RS09515	COG0419	ATPase involved in DNA repair
FOC75_RS09535	COG2223	nitrite transmembrane transporter activity
FOC75_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS09545	COG1169	isochorismate synthase
FOC75_RS09550	COG1021	2,3-dihydroxybenzoate-AMP ligase
FOC75_RS09555	COG1535	isochorismatase
FOC75_RS09555	COG3433	isochorismatase activity
FOC75_RS09560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOC75_RS09565	COG3251	PFAM MbtH domain protein
FOC75_RS09570	COG2814	Major facilitator Superfamily
FOC75_RS09585	COG0776	regulation of translation
FOC75_RS09595	COG2318	DinB family
FOC75_RS09605	COG1115	amino acid carrier protein
FOC75_RS09620	COG2329	Antibiotic biosynthesis monooxygenase
FOC75_RS09625	COG1187	pseudouridine synthase activity
FOC75_RS09630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC75_RS09635	COG1136	(ABC) transporter
FOC75_RS09645	COG0596	Alpha beta hydrolase
FOC75_RS09665	COG2226	methyltransferase
FOC75_RS09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS09735	COG1247	-acetyltransferase
FOC75_RS09775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS09785	COG1278	Cold shock
FOC75_RS09800	COG0010	Belongs to the arginase family
FOC75_RS09805	COG0561	phosphatase activity
FOC75_RS09850	COG0583	DNA-binding transcription factor activity
FOC75_RS09855	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC75_RS09870	COG0583	DNA-binding transcription factor activity
FOC75_RS09875	COG2258	MOSC domain
FOC75_RS09890	COG1132	(ABC) transporter
FOC75_RS09895	COG1132	(ABC) transporter
FOC75_RS09915	COG1396	sequence-specific DNA binding
FOC75_RS09945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC75_RS09955	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FOC75_RS09960	COG1595	DNA-templated transcription, initiation
FOC75_RS09985	COG1649	PFAM Uncharacterised BCR, COG1649
FOC75_RS10010	COG2971	BadF BadG BcrA BcrD
FOC75_RS10020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOC75_RS10055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS10085	COG1309	transcriptional regulator
FOC75_RS10100	COG1136	(ABC) transporter
FOC75_RS10100	COG0577	efflux transmembrane transporter activity
FOC75_RS10105	COG3615	Tellurite resistance protein tehB
FOC75_RS10105	COG0500	methyltransferase
FOC75_RS10120	COG3961	Belongs to the TPP enzyme family
FOC75_RS10125	COG1846	Transcriptional regulator
FOC75_RS10160	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC75_RS10175	COG1595	DNA-templated transcription, initiation
FOC75_RS10195	COG2367	Beta-lactamase
FOC75_RS10200	COG0671	phosphoesterase, PA-phosphatase related
FOC75_RS10205	COG1609	Transcriptional regulator
FOC75_RS10210	COG2814	Major facilitator Superfamily
FOC75_RS10215	COG0673	inositol 2-dehydrogenase activity
FOC75_RS10245	COG3718	enzyme involved in inositol metabolism
FOC75_RS10260	COG0737	Belongs to the 5'-nucleotidase family
FOC75_RS10270	COG0457	Tetratricopeptide repeat
FOC75_RS10275	COG1476	TRANSCRIPTIONal
FOC75_RS10290	COG1876	peptidase activity
FOC75_RS10310	COG1309	transcriptional regulator
FOC75_RS10345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC75_RS10360	COG1131	(ABC) transporter
FOC75_RS10370	COG1309	transcriptional regulator
FOC75_RS10385	COG1960	acyl-CoA dehydrogenase activity
FOC75_RS10390	COG0439	Biotin carboxylase
FOC75_RS10395	COG0511	ligase activity, forming carbon-carbon bonds
FOC75_RS10400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC75_RS10405	COG1024	Enoyl-CoA hydratase
FOC75_RS10410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC75_RS10415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC75_RS10425	COG1247	-acetyltransferase
FOC75_RS10430	COG0572	uridine kinase
FOC75_RS10440	COG2318	DinB family
FOC75_RS10445	COG1686	Belongs to the peptidase S11 family
FOC75_RS10470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC75_RS10490	COG3227	Zinc metalloprotease (Elastase)
FOC75_RS10530	COG2814	Major facilitator Superfamily
FOC75_RS10550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC75_RS10570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS10585	COG1063	alcohol dehydrogenase
FOC75_RS10605	COG3386	PFAM SMP-30 Gluconolaconase
FOC75_RS10615	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FOC75_RS10620	COG3773	Cell wall hydrolase
FOC75_RS10630	COG0745	RESPONSE REGULATOR receiver
FOC75_RS10635	COG2205	protein histidine kinase activity
FOC75_RS10660	COG1136	(ABC) transporter
FOC75_RS10665	COG0577	efflux transmembrane transporter activity
FOC75_RS10685	COG0460	homoserine dehydrogenase
FOC75_RS10690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS10700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FOC75_RS10735	COG0582	viral genome integration into host DNA
FOC75_RS10780	COG1484	DNA-dependent DNA replication
FOC75_RS10825	COG0662	Cupin 2, conserved barrel domain protein
FOC75_RS10870	COG0582	viral genome integration into host DNA
FOC75_RS10975	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS11020	COG2124	cytochrome p450
FOC75_RS11055	COG0561	phosphatase activity
FOC75_RS11060	COG5002	protein histidine kinase activity
FOC75_RS11070	COG1819	glycosyl
FOC75_RS11075	COG1794	racemase activity, acting on amino acids and derivatives
FOC75_RS11100	COG2205	protein histidine kinase activity
FOC75_RS11115	COG0604	alcohol dehydrogenase
FOC75_RS11120	COG0671	phosphoesterase, PA-phosphatase related
FOC75_RS11135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC75_RS11170	COG0693	protein deglycase activity
FOC75_RS11200	COG2814	Major facilitator Superfamily
FOC75_RS11215	COG0584	glycerophosphoryl diester phosphodiesterase
FOC75_RS11230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS11235	COG0697	spore germination
FOC75_RS11275	COG2223	nitrite transmembrane transporter activity
FOC75_RS11295	COG0592	DNA-directed DNA polymerase activity
FOC75_RS11300	COG1051	belongs to the nudix hydrolase family
FOC75_RS11335	COG3878	Protein conserved in bacteria
FOC75_RS11355	COG4667	esterase of the alpha-beta hydrolase superfamily
FOC75_RS11380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC75_RS11395	COG0322	excinuclease ABC activity
FOC75_RS11435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC75_RS11460	COG1011	Hydrolase
FOC75_RS11475	COG1073	alpha beta
FOC75_RS11485	COG0076	glutamate decarboxylase activity
FOC75_RS11500	COG1523	belongs to the glycosyl hydrolase 13 family
FOC75_RS11505	COG3227	Zinc metalloprotease (Elastase)
FOC75_RS11525	COG0201	protein transport
FOC75_RS11535	COG0697	spore germination
FOC75_RS11540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS11575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS11590	COG2959	enzyme of heme biosynthesis
FOC75_RS11625	COG1309	transcriptional regulator
FOC75_RS11645	COG3284	Transcriptional regulator
FOC75_RS11665	COG1349	DNA-binding transcription factor activity
FOC75_RS11685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC75_RS11690	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC75_RS11695	COG0022	dehydrogenase e1 component
FOC75_RS11700	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC75_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS11715	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC75_RS11715	COG0456	acetyltransferase
FOC75_RS11755	COG4176	ABC-type proline glycine betaine transport system permease component
FOC75_RS11760	COG0517	IMP dehydrogenase activity
FOC75_RS11760	COG4175	Glycine betaine
FOC75_RS11785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC75_RS11790	COG2153	protein acetylation
FOC75_RS11795	COG3397	chitin binding
FOC75_RS11800	COG1819	glycosyl
FOC75_RS11815	COG2205	protein histidine kinase activity
FOC75_RS11820	COG2226	methyltransferase
FOC75_RS11845	COG2333	competence protein COMEC
FOC75_RS11845	COG0658	competence protein
FOC75_RS11895	COG3973	AAA domain
FOC75_RS11910	COG2105	PFAM AIG2 family protein
FOC75_RS11915	COG0514	ATP-dependent DNA helicase (RecQ)
FOC75_RS11935	COG4637	Psort location Cytoplasmic, score
FOC75_RS11960	COG3397	chitin binding
FOC75_RS11975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOC75_RS11980	COG1115	amino acid carrier protein
FOC75_RS11985	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS11990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC75_RS12000	COG3938	Belongs to the proline racemase family
FOC75_RS12005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC75_RS12045	COG0586	Pfam SNARE associated Golgi protein
FOC75_RS12060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FOC75_RS12065	COG0519	Catalyzes the synthesis of GMP from XMP
FOC75_RS12070	COG4166	transmembrane transport
FOC75_RS12080	COG4948	Mandelate Racemase Muconate Lactonizing
FOC75_RS12125	COG2936	dipeptidyl-peptidase activity
FOC75_RS12130	COG5002	protein histidine kinase activity
FOC75_RS12135	COG0745	RESPONSE REGULATOR receiver
FOC75_RS12170	COG1164	Oligoendopeptidase f
FOC75_RS12180	COG1307	EDD domain protein, DegV family
FOC75_RS12200	COG2814	Major facilitator Superfamily
FOC75_RS12210	COG1664	Polymer-forming cytoskeletal
FOC75_RS12215	COG0789	Transcriptional regulator
FOC75_RS12220	COG4533	DNA binding
FOC75_RS12225	COG0477	Major facilitator Superfamily
FOC75_RS12225	COG2814	Major facilitator Superfamily
FOC75_RS12245	COG2261	transglycosylase associated protein
FOC75_RS12260	COG2226	methyltransferase
FOC75_RS12300	COG0436	Aminotransferase
FOC75_RS12305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC75_RS12315	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FOC75_RS12330	COG1131	(ABC) transporter
FOC75_RS12380	COG0628	permease
FOC75_RS12390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC75_RS12395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC75_RS12400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC75_RS12445	COG2746	aminoglycoside 3-N-acetyltransferase activity
FOC75_RS12470	COG0697	spore germination
FOC75_RS12475	COG2318	DinB family
FOC75_RS12495	COG4912	Dna alkylation repair
FOC75_RS12515	COG0861	Integral membrane protein TerC family
FOC75_RS12520	COG1368	sulfuric ester hydrolase activity
FOC75_RS12525	COG0488	(ABC) transporter
FOC75_RS12535	COG1033	growth of symbiont in host cell
FOC75_RS12535	COG2409	Drug exporters of the RND superfamily
FOC75_RS12540	COG1309	transcriptional regulator
FOC75_RS12555	COG0287	Prephenate dehydrogenase
FOC75_RS12560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC75_RS12570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC75_RS12570	COG1605	Chorismate mutase
FOC75_RS12605	COG3584	3D domain protein
FOC75_RS12605	COG1388	LysM domain
FOC75_RS12615	COG2610	gluconate transmembrane transporter activity
FOC75_RS12620	COG1024	Enoyl-CoA hydratase
FOC75_RS12630	COG3290	protein histidine kinase activity
FOC75_RS12630	COG3829	transcription factor binding
FOC75_RS12645	COG1879	ABC-type sugar transport system periplasmic component
FOC75_RS12655	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOC75_RS12665	COG2390	Transcriptional regulator
FOC75_RS12670	COG1070	Carbohydrate kinase
FOC75_RS12705	COG2329	Antibiotic biosynthesis monooxygenase
FOC75_RS12725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS12735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC75_RS12740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC75_RS12765	COG4187	Peptidase family M20/M25/M40
FOC75_RS12770	COG1414	Transcriptional regulator
FOC75_RS12775	COG0833	amino acid
FOC75_RS12780	COG1690	Belongs to the RtcB family
FOC75_RS12785	COG3239	Fatty acid desaturase
FOC75_RS12790	COG1785	Belongs to the alkaline phosphatase family
FOC75_RS12800	COG3655	Transcriptional regulator
FOC75_RS12815	COG4377	Putative membrane peptidase family (DUF2324)
FOC75_RS12825	COG3279	Response regulator of the LytR AlgR family
FOC75_RS12835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS12840	COG0346	lactoylglutathione lyase activity
FOC75_RS12860	COG0714	Associated with various cellular activities
FOC75_RS12885	COG0463	Glycosyl transferase, family 2
FOC75_RS12905	COG0463	Glycosyl transferase, family 2
FOC75_RS12915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC75_RS12920	COG0753	catalase activity
FOC75_RS12930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC75_RS12960	COG0778	Nitroreductase
FOC75_RS12965	COG1846	Transcriptional regulator
FOC75_RS12985	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC75_RS12995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOC75_RS13000	COG0824	Thioesterase
FOC75_RS13005	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS13010	COG0183	Belongs to the thiolase family
FOC75_RS13015	COG1024	Enoyl-CoA hydratase
FOC75_RS13020	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC75_RS13025	COG2723	6-phospho-beta-galactosidase activity
FOC75_RS13030	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC75_RS13035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC75_RS13050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC75_RS13060	COG2508	Transcriptional regulator
FOC75_RS13065	COG2814	Major facilitator Superfamily
FOC75_RS13070	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC75_RS13100	COG1725	Transcriptional regulator
FOC75_RS13110	COG1136	(ABC) transporter
FOC75_RS13135	COG2207	Transcriptional regulator
FOC75_RS13140	COG0456	acetyltransferase
FOC75_RS13160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS13205	COG0730	response to heat
FOC75_RS13215	COG0833	amino acid
FOC75_RS13225	COG4335	DNA alkylation repair
FOC75_RS13265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC75_RS13295	COG1984	allophanate hydrolase subunit 2
FOC75_RS13300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOC75_RS13305	COG1414	Transcriptional regulator
FOC75_RS13320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS13325	COG0640	Transcriptional regulator
FOC75_RS13335	COG1960	acyl-CoA dehydrogenase activity
FOC75_RS13365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FOC75_RS13380	COG0574	Belongs to the PEP-utilizing enzyme family
FOC75_RS13380	COG3848	Pyruvate phosphate dikinase
FOC75_RS13385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS13400	COG5577	PFAM Coat F domain
FOC75_RS13405	COG3403	YqcI/YcgG family
FOC75_RS13410	COG1280	lysine exporter protein (LysE YggA)
FOC75_RS13415	COG1113	amino acid transport
FOC75_RS13445	COG1063	alcohol dehydrogenase
FOC75_RS13455	COG1027	Aspartate ammonia-lyase
FOC75_RS13460	COG0252	asparaginase activity
FOC75_RS13465	COG1396	sequence-specific DNA binding
FOC75_RS13475	COG0322	excinuclease ABC activity
FOC75_RS13480	COG0531	amino acid
FOC75_RS13485	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS13490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC75_RS13510	COG0531	amino acid
FOC75_RS13515	COG0697	spore germination
FOC75_RS13520	COG0784	Response regulator, receiver
FOC75_RS13525	COG4191	Histidine kinase
FOC75_RS13530	COG2066	Belongs to the glutaminase family
FOC75_RS13535	COG1115	amino acid carrier protein
FOC75_RS13545	COG0737	Belongs to the 5'-nucleotidase family
FOC75_RS13550	COG0753	catalase activity
FOC75_RS13555	COG2267	carboxylic ester hydrolase activity
FOC75_RS13560	COG1335	isochorismatase
FOC75_RS13580	COG0583	DNA-binding transcription factor activity
FOC75_RS13585	COG1846	Transcriptional regulator
FOC75_RS13590	COG0598	Magnesium transport protein CorA
FOC75_RS13625	COG0415	Belongs to the DNA photolyase family
FOC75_RS13630	COG0288	reversible hydration of carbon dioxide
FOC75_RS13640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC75_RS13645	COG5609	conserved protein (DUF2294)
FOC75_RS13660	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC75_RS13665	COG2267	carboxylic ester hydrolase activity
FOC75_RS13670	COG4641	Protein conserved in bacteria
FOC75_RS13675	COG1136	(ABC) transporter
FOC75_RS13700	COG0798	PFAM Bile acid sodium symporter
FOC75_RS13705	COG0640	Transcriptional regulator
FOC75_RS13725	COG5002	protein histidine kinase activity
FOC75_RS13730	COG0745	RESPONSE REGULATOR receiver
FOC75_RS13735	COG0456	acetyltransferase
FOC75_RS13745	COG3320	Male sterility
FOC75_RS13745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC75_RS13750	COG1309	transcriptional regulator
FOC75_RS13760	COG1522	sequence-specific DNA binding
FOC75_RS13775	COG0346	lactoylglutathione lyase activity
FOC75_RS13795	COG2169	Transcriptional regulator
FOC75_RS13850	COG2814	Major facilitator Superfamily
FOC75_RS13875	COG0745	RESPONSE REGULATOR receiver
FOC75_RS13880	COG5002	protein histidine kinase activity
FOC75_RS13880	COG3850	Histidine kinase
FOC75_RS13905	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FOC75_RS13930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS13935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC75_RS13945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS13965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FOC75_RS13980	COG1136	(ABC) transporter
FOC75_RS13985	COG0577	efflux transmembrane transporter activity
FOC75_RS14000	COG5002	protein histidine kinase activity
FOC75_RS14000	COG3850	Histidine kinase
FOC75_RS14010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS14015	COG2271	Major facilitator Superfamily
FOC75_RS14020	COG1556	Lactate utilization protein
FOC75_RS14025	COG1139	Iron-sulfur cluster binding protein
FOC75_RS14035	COG0583	DNA-binding transcription factor activity
FOC75_RS14045	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC75_RS14065	COG0738	Major facilitator superfamily
FOC75_RS14070	COG0673	inositol 2-dehydrogenase activity
FOC75_RS14075	COG0561	phosphatase activity
FOC75_RS14080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC75_RS14085	COG1609	Transcriptional regulator
FOC75_RS14090	COG0457	Tetratricopeptide repeat
FOC75_RS14110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC75_RS14135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS14145	COG0814	amino acid
FOC75_RS14150	COG1760	l-serine dehydratase
FOC75_RS14155	COG1760	l-serine dehydratase
FOC75_RS14165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC75_RS14170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOC75_RS14180	COG1335	isochorismatase
FOC75_RS14185	COG1522	sequence-specific DNA binding
FOC75_RS14190	COG0531	amino acid
FOC75_RS14205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC75_RS14225	COG1595	DNA-templated transcription, initiation
FOC75_RS14240	COG0662	Cupin 2, conserved barrel domain protein
FOC75_RS14245	COG2207	Transcriptional regulator
FOC75_RS14245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS14265	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS14265	COG3409	Peptidoglycan-binding domain 1 protein
FOC75_RS14305	COG0477	Major facilitator Superfamily
FOC75_RS14315	COG1846	Transcriptional regulator
FOC75_RS14320	COG2814	Major facilitator Superfamily
FOC75_RS14335	COG2076	Multidrug Resistance protein
FOC75_RS14340	COG1309	transcriptional regulator
FOC75_RS14350	COG2031	fatty acid transporter
FOC75_RS14360	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC75_RS14395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC75_RS14410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOC75_RS14415	COG1288	antiporter activity
FOC75_RS14430	COG2814	Major facilitator Superfamily
FOC75_RS14435	COG1309	transcriptional regulator
FOC75_RS14450	COG3344	reverse transcriptase
FOC75_RS14455	COG0537	adenosine 5'-monophosphoramidase activity
FOC75_RS14460	COG1051	belongs to the nudix hydrolase family
FOC75_RS14465	COG3344	reverse transcriptase
FOC75_RS14470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC75_RS14490	COG1733	regulation of RNA biosynthetic process
FOC75_RS14495	COG0778	Nitroreductase
FOC75_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS14525	COG1131	(ABC) transporter
FOC75_RS14550	COG1011	Hydrolase
FOC75_RS14585	COG0346	lactoylglutathione lyase activity
FOC75_RS14590	COG1940	carbohydrate kinase activity
FOC75_RS14595	COG0738	Major facilitator superfamily
FOC75_RS14600	COG0110	maltose O-acetyltransferase activity
FOC75_RS14610	COG0577	efflux transmembrane transporter activity
FOC75_RS14610	COG1136	(ABC) transporter
FOC75_RS14630	COG0628	permease
FOC75_RS14650	COG2226	methyltransferase
FOC75_RS14660	COG0477	Major facilitator Superfamily
FOC75_RS14690	COG1253	flavin adenine dinucleotide binding
FOC75_RS14695	COG0789	Transcriptional regulator
FOC75_RS14700	COG0697	spore germination
FOC75_RS14705	COG1357	PFAM Pentapeptide repeats (8 copies)
FOC75_RS14710	COG3813	Protein conserved in bacteria
FOC75_RS14715	COG2706	6-phosphogluconolactonase activity
FOC75_RS14720	COG1070	Carbohydrate kinase
FOC75_RS14730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC75_RS14735	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOC75_RS14745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC75_RS14760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOC75_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS14820	COG0814	amino acid
FOC75_RS14850	COG1393	Belongs to the ArsC family
FOC75_RS14860	COG2188	Transcriptional regulator
FOC75_RS14865	COG0673	inositol 2-dehydrogenase activity
FOC75_RS14870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOC75_RS14875	COG1733	regulation of RNA biosynthetic process
FOC75_RS14880	COG1733	regulation of RNA biosynthetic process
FOC75_RS14895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS14915	COG0384	phenazine biosynthesis protein PhzF
FOC75_RS14940	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS14945	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC75_RS14950	COG1733	regulation of RNA biosynthetic process
FOC75_RS14970	COG1191	sigma factor activity
FOC75_RS14985	COG1309	transcriptional regulator
FOC75_RS15005	COG3152	Membrane
FOC75_RS15030	COG1151	hydroxylamine reductase activity
FOC75_RS15040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS15080	COG2072	flavoprotein involved in K transport
FOC75_RS15115	COG0604	alcohol dehydrogenase
FOC75_RS15120	COG1113	amino acid transport
FOC75_RS15125	COG2814	Major facilitator Superfamily
FOC75_RS15155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC75_RS15160	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC75_RS15175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS15180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS15185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS15190	COG3739	integral membrane protein
FOC75_RS15195	COG0384	phenazine biosynthesis protein PhzF
FOC75_RS15230	COG0583	DNA-binding transcription factor activity
FOC75_RS15250	COG1193	negative regulation of DNA recombination
FOC75_RS15265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FOC75_RS15270	COG1164	Oligoendopeptidase f
FOC75_RS15275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC75_RS15305	COG0584	glycerophosphoryl diester phosphodiesterase
FOC75_RS15330	COG0640	Transcriptional regulator
FOC75_RS15335	COG0604	alcohol dehydrogenase
FOC75_RS15345	COG0457	Tetratricopeptide repeat
FOC75_RS15355	COG2808	Putative FMN-binding domain
FOC75_RS15360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC75_RS15370	COG0385	Bile acid
FOC75_RS15410	COG1216	Glycosyl transferase, family 2
FOC75_RS15415	COG1024	Enoyl-CoA hydratase
FOC75_RS15425	COG1285	pathogenesis
FOC75_RS15440	COG2514	catechol 2,3-dioxygenase activity
FOC75_RS15445	COG2720	vancomycin resistance protein
FOC75_RS15485	COG0716	FMN binding
FOC75_RS15495	COG1051	belongs to the nudix hydrolase family
FOC75_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS15525	COG0165	Argininosuccinate lyase
FOC75_RS15540	COG4145	pantothenate transmembrane transporter activity
FOC75_RS15550	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS15555	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS15565	COG1657	PFAM Prenyltransferase squalene oxidase
FOC75_RS15570	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FOC75_RS15575	COG2962	Rard protein
FOC75_RS15595	COG0489	protein tyrosine kinase activity
FOC75_RS15605	COG0314	molybdopterin synthase activity
FOC75_RS15610	COG0303	'Molybdopterin
FOC75_RS15615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC75_RS15620	COG2116	formate transmembrane transporter activity
FOC75_RS15630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FOC75_RS15635	COG5609	conserved protein (DUF2294)
FOC75_RS15640	COG2427	Protein of unknown function (DUF1641)
FOC75_RS15645	COG3383	formate dehydrogenase (NAD+) activity
FOC75_RS15650	COG0697	spore germination
FOC75_RS15690	COG2226	methyltransferase
FOC75_RS15695	COG4166	transmembrane transport
FOC75_RS15705	COG4166	transmembrane transport
FOC75_RS15710	COG4166	transmembrane transport
FOC75_RS15715	COG1301	dicarboxylic acid transport
FOC75_RS15720	COG1316	TRANSCRIPTIONal
FOC75_RS15730	COG1595	DNA-templated transcription, initiation
FOC75_RS15750	COG1131	(ABC) transporter
FOC75_RS15760	COG0673	inositol 2-dehydrogenase activity
FOC75_RS15765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC75_RS15770	COG0187	DNA topoisomerase II activity
FOC75_RS15775	COG1832	CoA-binding protein
FOC75_RS15780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC75_RS15785	COG0745	RESPONSE REGULATOR receiver
FOC75_RS15805	COG4841	protein insertion into membrane
FOC75_RS15810	COG0824	Thioesterase
FOC75_RS15840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC75_RS15850	COG2274	protein secretion by the type I secretion system
FOC75_RS15855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOC75_RS15895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC75_RS15910	COG0183	Belongs to the thiolase family
FOC75_RS15915	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS15920	COG1268	BioY protein
FOC75_RS15925	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS15980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS15990	COG5002	protein histidine kinase activity
FOC75_RS15995	COG0400	carboxylic ester hydrolase activity
FOC75_RS16000	COG0346	lactoylglutathione lyase activity
FOC75_RS16005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC75_RS16010	COG0069	glutamate synthase activity
FOC75_RS16015	COG1902	pentaerythritol trinitrate reductase activity
FOC75_RS16020	COG1329	Transcriptional regulator
FOC75_RS16025	COG0010	Belongs to the arginase family
FOC75_RS16085	COG4846	Membrane protein involved in cytochrome C biogenesis
FOC75_RS16090	COG0785	Cytochrome C biogenesis protein
FOC75_RS16100	COG1473	amidohydrolase
FOC75_RS16110	COG1131	(ABC) transporter
FOC75_RS16120	COG0583	DNA-binding transcription factor activity
FOC75_RS16130	COG1346	cytolysis
FOC75_RS16145	COG0730	response to heat
FOC75_RS16155	COG5632	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS16155	COG3409	Peptidoglycan-binding domain 1 protein
FOC75_RS16170	COG1132	(ABC) transporter
FOC75_RS16175	COG1132	(ABC) transporter
FOC75_RS16205	COG3639	organic phosphonate transmembrane transporter activity
FOC75_RS16210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOC75_RS16220	COG0737	Belongs to the 5'-nucleotidase family
FOC75_RS16230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC75_RS16250	COG1695	Transcriptional regulator
FOC75_RS16265	COG5444	nuclease activity
FOC75_RS16280	COG0174	glutamine synthetase
FOC75_RS16285	COG0789	Transcriptional regulator
FOC75_RS16290	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FOC75_RS16295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC75_RS16300	COG2860	membrane
FOC75_RS16305	COG0464	growth
FOC75_RS16335	COG1388	LysM domain
FOC75_RS16335	COG3584	3D domain protein
FOC75_RS16340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC75_RS16340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FOC75_RS16340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC75_RS16345	COG1105	Belongs to the carbohydrate kinase PfkB family
FOC75_RS16350	COG1349	DNA-binding transcription factor activity
FOC75_RS16355	COG1979	alcohol dehydrogenase
FOC75_RS16360	COG2322	membrane
FOC75_RS16370	COG1113	amino acid transport
FOC75_RS16385	COG1408	metallophosphoesterase
FOC75_RS16390	COG2116	formate transmembrane transporter activity
FOC75_RS16405	COG2217	Heavy metal translocating P-type atpase
FOC75_RS16410	COG2608	mercury ion transmembrane transporter activity
FOC75_RS16415	COG1937	Protein conserved in bacteria
FOC75_RS16425	COG2819	hydrolase of the alpha beta superfamily
FOC75_RS16430	COG1120	ATPase activity
FOC75_RS16435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS16440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS16445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS16450	COG0708	Exodeoxyribonuclease III
FOC75_RS16455	COG2169	Transcriptional regulator
FOC75_RS16460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC75_RS16465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC75_RS16475	COG2364	Membrane
FOC75_RS16490	COG2267	carboxylic ester hydrolase activity
FOC75_RS16495	COG0346	lactoylglutathione lyase activity
FOC75_RS16500	COG5001	Diguanylate cyclase
FOC75_RS16500	COG3300	MHYT domain
FOC75_RS16515	COG1346	cytolysis
FOC75_RS16520	COG1380	Effector of murein hydrolase LrgA
FOC75_RS16525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS16530	COG0596	Alpha beta hydrolase
FOC75_RS16530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC75_RS16535	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FOC75_RS16555	COG1404	Belongs to the peptidase S8 family
FOC75_RS16560	COG3773	Cell wall hydrolase
FOC75_RS16565	COG0562	UDP-galactopyranose mutase
FOC75_RS16570	COG1368	sulfuric ester hydrolase activity
FOC75_RS16575	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FOC75_RS16585	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FOC75_RS16605	COG4550	Control of competence regulator ComK, YlbF/YmcA
FOC75_RS16615	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC75_RS16620	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC75_RS16620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC75_RS16630	COG2359	stage V sporulation protein S
FOC75_RS16635	COG1692	metallophosphoesterase
FOC75_RS16660	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC75_RS16665	COG1426	Protein conserved in bacteria
FOC75_RS16680	COG0300	oxidoreductase activity
FOC75_RS16685	COG0612	Peptidase, M16
FOC75_RS16690	COG0612	Peptidase, M16
FOC75_RS16715	COG2188	Transcriptional regulator
FOC75_RS16720	COG1674	ftsk spoiiie
FOC75_RS16730	COG0740	serine-type endopeptidase activity
FOC75_RS16735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC75_RS16745	COG0527	aspartate kinase activity
FOC75_RS16750	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC75_RS16755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC75_RS16760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC75_RS16765	COG1873	PFAM PRC-barrel domain
FOC75_RS16770	COG0612	Peptidase, M16
FOC75_RS16775	COG0726	polysaccharide deacetylase
FOC75_RS16790	COG0196	riboflavin kinase activity
FOC75_RS16795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC75_RS16805	COG1550	Protein conserved in bacteria
FOC75_RS16815	COG1358	cellular component organization or biogenesis
FOC75_RS16820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FOC75_RS16825	COG0195	Participates in both transcription termination and antitermination
FOC75_RS16845	COG0750	zinc metalloprotease
FOC75_RS16855	COG4589	Belongs to the CDS family
FOC75_RS16870	COG0528	UMP kinase activity
FOC75_RS16900	COG4974	Belongs to the 'phage' integrase family
FOC75_RS16910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC75_RS16915	COG0758	DNA mediated transformation
FOC75_RS16920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC75_RS16960	COG1837	Belongs to the UPF0109 family
FOC75_RS16970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC75_RS16980	COG0552	protein localization to endoplasmic reticulum
FOC75_RS16985	COG1196	nuclear chromosome segregation
FOC75_RS16995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC75_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS17005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC75_RS17020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC75_RS17025	COG1461	Dihydroxyacetone kinase
FOC75_RS17030	COG1302	Protein conserved in bacteria
FOC75_RS17045	COG1564	THIamine pyrophosphokinase
FOC75_RS17050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC75_RS17055	COG1162	GTPase activity
FOC75_RS17060	COG0515	serine threonine protein kinase
FOC75_RS17060	COG2815	serine threonine protein kinase
FOC75_RS17065	COG0631	protein serine/threonine phosphatase activity
FOC75_RS17075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC75_RS17075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC75_RS17085	COG0242	peptide deformylase activity
FOC75_RS17090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC75_RS17095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOC75_RS17115	COG1561	YicC-like family, N-terminal region
FOC75_RS17120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC75_RS17130	COG0006	proline dipeptidase activity
FOC75_RS17145	COG3069	C4-dicarboxylate transmembrane transporter activity
FOC75_RS17210	COG0564	pseudouridine synthase activity
FOC75_RS17230	COG3599	regulation of cell shape
FOC75_RS17235	COG2302	S4 RNA-binding domain
FOC75_RS17240	COG0762	integral membrane protein
FOC75_RS17250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC75_RS17260	COG1873	PFAM PRC-barrel domain
FOC75_RS17265	COG1191	sigma factor activity
FOC75_RS17270	COG1191	sigma factor activity
FOC75_RS17280	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC75_RS17285	COG0849	cell division
FOC75_RS17290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOC75_RS17295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC75_RS17305	COG0772	Belongs to the SEDS family
FOC75_RS17320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC75_RS17325	COG0768	penicillin binding
FOC75_RS17335	COG4839	cell division protein FtsL
FOC75_RS17350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC75_RS17365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOC75_RS17370	COG1399	metal-binding, possibly nucleic acid-binding protein
FOC75_RS17380	COG3480	Lon protease (S16) C-terminal proteolytic domain
FOC75_RS17385	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC75_RS17390	COG3314	Sporulation integral membrane protein YlbJ
FOC75_RS17400	COG0742	ribosomal rna small subunit methyltransferase
FOC75_RS17415	COG3679	Belongs to the UPF0342 family
FOC75_RS17420	COG0406	alpha-ribazole phosphatase activity
FOC75_RS17435	COG2340	Cysteine-rich secretory protein family
FOC75_RS17450	COG3344	reverse transcriptase
FOC75_RS17460	COG3336	cytochrome c oxidase
FOC75_RS17495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FOC75_RS17500	COG0772	Belongs to the SEDS family
FOC75_RS17510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOC75_RS17515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC75_RS17525	COG4896	Protein conserved in bacteria
FOC75_RS17550	COG0483	inositol monophosphate 1-phosphatase activity
FOC75_RS17570	COG1982	Orn Lys Arg decarboxylase major
FOC75_RS17620	COG0022	dehydrogenase e1 component
FOC75_RS17625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC75_RS17635	COG0242	peptide deformylase activity
FOC75_RS17640	COG0561	phosphatase activity
FOC75_RS17650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FOC75_RS17655	COG0569	domain protein
FOC75_RS17675	COG0583	DNA-binding transcription factor activity
FOC75_RS17680	COG0517	IMP dehydrogenase activity
FOC75_RS17690	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FOC75_RS17700	COG4703	Protein of unknown function (DUF1797)
FOC75_RS17715	COG2200	EAL domain
FOC75_RS17720	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS17725	COG1408	metallophosphoesterase
FOC75_RS17735	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC75_RS17770	COG2814	Major facilitator Superfamily
FOC75_RS17790	COG3209	COG3209 Rhs family protein
FOC75_RS17800	COG2205	protein histidine kinase activity
FOC75_RS17810	COG0436	Aminotransferase
FOC75_RS17815	COG1609	Transcriptional regulator
FOC75_RS17820	COG3833	ABC-type maltose transport systems, permease component
FOC75_RS17825	COG1175	transmembrane transport
FOC75_RS17830	COG2182	Extracellular solute-binding protein
FOC75_RS17840	COG0366	Alpha amylase catalytic
FOC75_RS17845	COG3842	ATPase activity
FOC75_RS17885	COG0183	Belongs to the thiolase family
FOC75_RS17920	COG1695	Transcriptional regulator
FOC75_RS17925	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS17945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC75_RS17950	COG0436	Aminotransferase
FOC75_RS17985	COG2084	Dehydrogenase
FOC75_RS17990	COG3706	GGDEF domain
FOC75_RS17995	COG0778	Nitroreductase
FOC75_RS18020	COG2190	(PTS) system
FOC75_RS18020	COG1263	PTS System
FOC75_RS18020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC75_RS18025	COG3711	transcriptional antiterminator
FOC75_RS18035	COG2188	Transcriptional regulator
FOC75_RS18045	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC75_RS18070	COG1547	Domain of unknown function (DUF309)
FOC75_RS18075	COG0456	acetyltransferase
FOC75_RS18080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC75_RS18085	COG4086	secreted protein
FOC75_RS18090	COG0561	phosphatase activity
FOC75_RS18095	COG0697	spore germination
FOC75_RS18110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS18135	COG0733	neurotransmitter:sodium symporter activity
FOC75_RS18155	COG1686	Belongs to the peptidase S11 family
FOC75_RS18160	COG1725	Transcriptional regulator
FOC75_RS18165	COG1131	(ABC) transporter
FOC75_RS18180	COG1846	Transcriptional regulator
FOC75_RS18195	COG0598	Magnesium transport protein CorA
FOC75_RS18220	COG4974	Belongs to the 'phage' integrase family
FOC75_RS18230	COG0735	belongs to the Fur family
FOC75_RS18235	COG1300	Membrane
FOC75_RS18255	COG0667	Aldo Keto reductase
FOC75_RS18260	COG0656	L-ascorbic acid biosynthetic process
FOC75_RS18265	COG0456	acetyltransferase
FOC75_RS18265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FOC75_RS18275	COG0737	Belongs to the 5'-nucleotidase family
FOC75_RS18275	COG1525	nuclease
FOC75_RS18275	COG4085	toxin activity
FOC75_RS18285	COG0596	Alpha beta hydrolase
FOC75_RS18290	COG2056	Na+-H+ antiporter family
FOC75_RS18295	COG1609	Transcriptional regulator
FOC75_RS18300	COG0456	acetyltransferase
FOC75_RS18305	COG1073	alpha beta
FOC75_RS18320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC75_RS18320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC75_RS18325	COG0307	riboflavin synthase, alpha
FOC75_RS18350	COG4106	trans-aconitate 2-methyltransferase activity
FOC75_RS18355	COG2226	methyltransferase
FOC75_RS18355	COG1073	alpha beta
FOC75_RS18370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC75_RS18385	COG0737	Belongs to the 5'-nucleotidase family
FOC75_RS18395	COG1522	sequence-specific DNA binding
FOC75_RS18415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC75_RS18425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOC75_RS18440	COG0300	oxidoreductase activity
FOC75_RS18445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS18450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC75_RS18455	COG1760	l-serine dehydratase
FOC75_RS18460	COG1760	l-serine dehydratase
FOC75_RS18480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC75_RS18490	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC75_RS18495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS18510	COG1376	ErfK ybiS ycfS ynhG family protein
FOC75_RS18515	COG4129	membrane
FOC75_RS18520	COG1126	abc transporter atp-binding protein
FOC75_RS18525	COG0765	amino acid transport
FOC75_RS18530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC75_RS18545	COG2816	NAD+ diphosphatase activity
FOC75_RS18550	COG0772	Belongs to the SEDS family
FOC75_RS18555	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC75_RS18560	COG0022	dehydrogenase e1 component
FOC75_RS18565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOC75_RS18570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC75_RS18585	COG0280	phosphate acetyltransferase
FOC75_RS18590	COG3290	protein histidine kinase activity
FOC75_RS18590	COG3829	transcription factor binding
FOC75_RS18600	COG0584	glycerophosphoryl diester phosphodiesterase
FOC75_RS18605	COG3093	addiction module antidote protein HigA
FOC75_RS18615	COG0745	RESPONSE REGULATOR receiver
FOC75_RS18620	COG0750	zinc metalloprotease
FOC75_RS18625	COG0497	DNA recombination
FOC75_RS18635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FOC75_RS18645	COG0142	geranyltranstransferase activity
FOC75_RS18670	COG1302	Protein conserved in bacteria
FOC75_RS18675	COG0439	Biotin carboxylase
FOC75_RS18680	COG0511	ligase activity, forming carbon-carbon bonds
FOC75_RS18725	COG3854	ATPases associated with a variety of cellular activities
FOC75_RS18750	COG0006	proline dipeptidase activity
FOC75_RS18765	COG3872	metal-dependent enzyme
FOC75_RS18775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC75_RS18795	COG0095	Lipoate-protein ligase
FOC75_RS18800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC75_RS18805	COG1609	Transcriptional regulator
FOC75_RS18815	COG2076	Multidrug Resistance protein
FOC75_RS18820	COG2076	Multidrug Resistance protein
FOC75_RS18855	COG1131	(ABC) transporter
FOC75_RS18860	COG1725	Transcriptional regulator
FOC75_RS18890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC75_RS18945	COG4970	Tfp pilus assembly protein FimT
FOC75_RS18955	COG1459	type II secretion system
FOC75_RS19070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOC75_RS19115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC75_RS19120	COG1410	methionine synthase
FOC75_RS19120	COG0646	methionine synthase
FOC75_RS19125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC75_RS19125	COG0646	methionine synthase
FOC75_RS19130	COG0626	cystathionine gamma-synthase activity
FOC75_RS19135	COG0626	cystathionine gamma-synthase activity
FOC75_RS19155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS19165	COG1940	carbohydrate kinase activity
FOC75_RS19170	COG4483	Protein conserved in bacteria
FOC75_RS19175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC75_RS19180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC75_RS19185	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC75_RS19190	COG0704	Plays a role in the regulation of phosphate uptake
FOC75_RS19200	COG0581	inorganic phosphate transmembrane transporter activity
FOC75_RS19205	COG0573	inorganic phosphate transmembrane transporter activity
FOC75_RS19210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC75_RS19220	COG0477	Major facilitator Superfamily
FOC75_RS19225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC75_RS19250	COG0735	belongs to the Fur family
FOC75_RS19255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC75_RS19260	COG1121	(ABC) transporter
FOC75_RS19265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS19295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC75_RS19300	COG2384	SAM-dependent methyltransferase
FOC75_RS19305	COG2010	Cytochrome c
FOC75_RS19310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC75_RS19315	COG0358	DNA primase activity
FOC75_RS19330	COG0517	IMP dehydrogenase activity
FOC75_RS19345	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC75_RS19350	COG0295	cytidine deaminase activity
FOC75_RS19355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOC75_RS19365	COG1480	7TM receptor with intracellular HD hydrolase
FOC75_RS19370	COG1702	phosphate starvation-inducible protein PhoH
FOC75_RS19385	COG1610	YqeY-like protein
FOC75_RS19390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC75_RS19395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC75_RS19400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOC75_RS19430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC75_RS19435	COG1733	regulation of RNA biosynthetic process
FOC75_RS19460	COG1466	dna polymerase III delta subunit
FOC75_RS19470	COG2333	competence protein COMEC
FOC75_RS19470	COG0658	competence protein
FOC75_RS19475	COG2131	deaminase
FOC75_RS19480	COG1596	polysaccharide export
FOC75_RS19480	COG1555	photosystem II stabilization
FOC75_RS19485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC75_RS19490	COG2226	methyltransferase
FOC75_RS19495	COG0799	negative regulation of ribosome biogenesis
FOC75_RS19500	COG1713	HD superfamily hydrolase involved in NAD metabolism
FOC75_RS19510	COG1534	Rna-binding protein
FOC75_RS19520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FOC75_RS19525	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FOC75_RS19550	COG1595	DNA-templated transcription, initiation
FOC75_RS19560	COG0778	Nitroreductase
FOC75_RS19565	COG2357	RelA SpoT domain protein
FOC75_RS19575	COG1785	Belongs to the alkaline phosphatase family
FOC75_RS19585	COG2267	carboxylic ester hydrolase activity
FOC75_RS19620	COG1404	Belongs to the peptidase S8 family
FOC75_RS19625	COG3186	Phenylalanine-4-hydroxylase
FOC75_RS19635	COG2514	catechol 2,3-dioxygenase activity
FOC75_RS19640	COG2259	Doxx family
FOC75_RS19680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS19690	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS19690	COG1454	alcohol dehydrogenase
FOC75_RS19695	COG0626	cystathionine gamma-synthase activity
FOC75_RS19700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC75_RS19725	COG0768	penicillin binding
FOC75_RS19750	COG4122	O-methyltransferase activity
FOC75_RS19755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC75_RS19785	COG0628	permease
FOC75_RS19805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC75_RS19820	COG1104	cysteine desulfurase activity
FOC75_RS19825	COG1959	2 iron, 2 sulfur cluster binding
FOC75_RS19830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC75_RS19840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC75_RS19870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC75_RS19880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC75_RS19880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC75_RS19885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC75_RS19890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC75_RS19890	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC75_RS19900	COG2244	polysaccharide biosynthetic process
FOC75_RS19905	COG2323	membrane
FOC75_RS19915	COG1862	Preprotein translocase
FOC75_RS19945	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FOC75_RS19975	COG0157	Belongs to the NadC ModD family
FOC75_RS19980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC75_RS19985	COG1104	cysteine desulfurase activity
FOC75_RS19990	COG1827	regulation of RNA biosynthetic process
FOC75_RS19995	COG2258	MOSC domain
FOC75_RS20000	COG0077	Prephenate dehydratase
FOC75_RS20005	COG0577	efflux transmembrane transporter activity
FOC75_RS20010	COG0577	efflux transmembrane transporter activity
FOC75_RS20015	COG1136	(ABC) transporter
FOC75_RS20020	COG5002	protein histidine kinase activity
FOC75_RS20025	COG0745	RESPONSE REGULATOR receiver
FOC75_RS20035	COG3290	protein histidine kinase activity
FOC75_RS20045	COG2868	ribosomal protein
FOC75_RS20055	COG1530	ribonuclease E activity
FOC75_RS20060	COG1994	Peptidase M50
FOC75_RS20065	COG0739	heme binding
FOC75_RS20070	COG2894	cell division
FOC75_RS20090	COG1077	Cell shape determining protein MreB Mrl
FOC75_RS20110	COG0285	dihydrofolate synthase activity
FOC75_RS20125	COG1388	LysM domain
FOC75_RS20135	COG0113	porphobilinogen synthase activity
FOC75_RS20140	COG1587	Uroporphyrinogen-III synthase
FOC75_RS20150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC75_RS20160	COG1846	Transcriptional regulator
FOC75_RS20165	COG1764	response to oxidative stress
FOC75_RS20180	COG0470	DNA polymerase III
FOC75_RS20180	COG1067	ATP-dependent peptidase activity
FOC75_RS20230	COG0622	Phosphoesterase
FOC75_RS20245	COG5401	PFAM Sporulation and spore germination
FOC75_RS20265	COG1309	transcriptional regulator
FOC75_RS20280	COG2197	response regulator
FOC75_RS20315	COG2226	methyltransferase
FOC75_RS20320	COG1595	DNA-templated transcription, initiation
FOC75_RS20345	COG0640	Transcriptional regulator
FOC75_RS20360	COG0798	PFAM Bile acid sodium symporter
FOC75_RS20385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC75_RS20385	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC75_RS20410	COG2197	response regulator
FOC75_RS20415	COG2233	PERMEase
FOC75_RS20425	COG0402	S-adenosylhomocysteine deaminase activity
FOC75_RS20430	COG0402	S-adenosylhomocysteine deaminase activity
FOC75_RS20450	COG0444	Belongs to the ABC transporter superfamily
FOC75_RS20455	COG4608	Belongs to the ABC transporter superfamily
FOC75_RS20460	COG3275	phosphorelay sensor kinase activity
FOC75_RS20465	COG3279	Response regulator of the LytR AlgR family
FOC75_RS20475	COG1983	PspC domain protein
FOC75_RS20480	COG1396	sequence-specific DNA binding
FOC75_RS20485	COG0697	spore germination
FOC75_RS20495	COG1959	2 iron, 2 sulfur cluster binding
FOC75_RS20500	COG1668	transmembrane transport
FOC75_RS20505	COG4152	abc transporter atp-binding protein
FOC75_RS20510	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FOC75_RS20515	COG1360	Flagellar Motor Protein
FOC75_RS20520	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOC75_RS20525	COG1876	peptidase activity
FOC75_RS20530	COG0824	Thioesterase
FOC75_RS20535	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC75_RS20540	COG1053	succinate dehydrogenase
FOC75_RS20545	COG2009	succinate dehydrogenase
FOC75_RS20550	COG1719	4-vinyl reductase, 4VR
FOC75_RS20560	COG3118	belongs to the thioredoxin family
FOC75_RS20565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC75_RS20570	COG2086	electron transfer activity
FOC75_RS20575	COG1024	Enoyl-CoA hydratase
FOC75_RS20580	COG1309	transcriptional regulator
FOC75_RS20585	COG0318	PFAM AMP-dependent synthetase and ligase
FOC75_RS20605	COG2318	DinB family
FOC75_RS20630	COG1131	(ABC) transporter
FOC75_RS20635	COG2205	protein histidine kinase activity
FOC75_RS20640	COG0745	RESPONSE REGULATOR receiver
FOC75_RS20650	COG4895	conserved protein (DUF2196)
FOC75_RS20655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC75_RS20670	COG4509	Sortase family
FOC75_RS20675	COG1120	ATPase activity
FOC75_RS20690	COG5386	Cell surface protein
FOC75_RS20700	COG5386	Cell surface protein
FOC75_RS20705	COG1114	Component of the transport system for branched-chain amino acids
FOC75_RS20710	COG1187	pseudouridine synthase activity
FOC75_RS20720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOC75_RS20720	COG1796	DNA polymerase
FOC75_RS20725	COG1286	toxin biosynthetic process
FOC75_RS20770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC75_RS20780	COG1418	mRNA catabolic process
FOC75_RS20805	COG2814	Major facilitator Superfamily
FOC75_RS20810	COG1566	PFAM secretion protein HlyD family protein
FOC75_RS20815	COG1309	transcriptional regulator
FOC75_RS20820	COG1363	Peptidase, m42
FOC75_RS20845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC75_RS20855	COG1484	DNA-dependent DNA replication
FOC75_RS20860	COG3611	Membrane attachment protein
FOC75_RS20870	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOC75_RS20875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC75_RS20880	COG0237	dephospho-CoA kinase activity
FOC75_RS20885	COG1971	Probably functions as a manganese efflux pump
FOC75_RS20895	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC75_RS20895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC75_RS20900	COG5002	protein histidine kinase activity
FOC75_RS20905	COG0745	RESPONSE REGULATOR receiver
FOC75_RS20925	COG0538	isocitrate dehydrogenase activity
FOC75_RS20930	COG0372	Belongs to the citrate synthase family
FOC75_RS20940	COG0628	permease
FOC75_RS20945	COG3030	protein affecting phage T7 exclusion by the F plasmid
FOC75_RS20970	COG1725	Transcriptional regulator
FOC75_RS20975	COG0281	malic enzyme
FOC75_RS20980	COG0587	DNA-directed DNA polymerase activity
FOC75_RS20995	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC75_RS21015	COG4109	DRTGG domain
FOC75_RS21030	COG0006	proline dipeptidase activity
FOC75_RS21075	COG0662	Cupin 2, conserved barrel domain protein
FOC75_RS21085	COG1476	TRANSCRIPTIONal
FOC75_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS21105	COG0589	response to stress
FOC75_RS21145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS21170	COG0827	DNA restriction-modification system
FOC75_RS21175	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC75_RS21180	COG3874	Sporulation protein YtfJ
FOC75_RS21195	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FOC75_RS21205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC75_RS21220	COG1104	cysteine desulfurase activity
FOC75_RS21230	COG0583	DNA-binding transcription factor activity
FOC75_RS21235	COG0697	spore germination
FOC75_RS21240	COG1309	transcriptional regulator
FOC75_RS21245	COG1956	GAF domain-containing protein
FOC75_RS21250	COG0626	cystathionine gamma-synthase activity
FOC75_RS21280	COG1595	DNA-templated transcription, initiation
FOC75_RS21290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC75_RS21295	COG0454	-acetyltransferase
FOC75_RS21300	COG0517	IMP dehydrogenase activity
FOC75_RS21305	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOC75_RS21310	COG2267	carboxylic ester hydrolase activity
FOC75_RS21320	COG0745	RESPONSE REGULATOR receiver
FOC75_RS21330	COG0666	response to abiotic stimulus
FOC75_RS21365	COG1609	Transcriptional regulator
FOC75_RS21370	COG4851	CamS sex pheromone cAM373 precursor
FOC75_RS21375	COG3118	belongs to the thioredoxin family
FOC75_RS21385	COG2309	aminopeptidase activity
FOC75_RS21410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS21425	COG1674	ftsk spoiiie
FOC75_RS21435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC75_RS21445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC75_RS21450	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FOC75_RS21455	COG1363	Peptidase, m42
FOC75_RS21465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS21480	COG0510	thiamine kinase activity
FOC75_RS21485	COG1523	belongs to the glycosyl hydrolase 13 family
FOC75_RS21495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC75_RS21500	COG1349	DNA-binding transcription factor activity
FOC75_RS21505	COG1187	pseudouridine synthase activity
FOC75_RS21510	COG2244	polysaccharide biosynthetic process
FOC75_RS21515	COG2081	HI0933 family
FOC75_RS21520	COG2814	Major facilitator Superfamily
FOC75_RS21530	COG3832	glyoxalase III activity
FOC75_RS21550	COG1329	Transcriptional regulator
FOC75_RS21575	COG0314	molybdopterin synthase activity
FOC75_RS21580	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOC75_RS21585	COG0303	'Molybdopterin
FOC75_RS21595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC75_RS21600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC75_RS21620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOC75_RS21630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOC75_RS21670	COG2814	Major facilitator Superfamily
FOC75_RS21675	COG0475	glutathione-regulated potassium exporter activity
FOC75_RS21680	COG0490	domain, Protein
FOC75_RS21685	COG0582	viral genome integration into host DNA
FOC75_RS21695	COG1136	(ABC) transporter
FOC75_RS21715	COG1242	4 iron, 4 sulfur cluster binding
FOC75_RS21720	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FOC75_RS21735	COG1794	racemase activity, acting on amino acids and derivatives
FOC75_RS21755	COG2267	carboxylic ester hydrolase activity
FOC75_RS21760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC75_RS21765	COG0671	phosphoesterase, PA-phosphatase related
FOC75_RS21770	COG0438	transferase activity, transferring glycosyl groups
FOC75_RS21780	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOC75_RS21835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC75_RS21840	COG5002	protein histidine kinase activity
FOC75_RS21845	COG4191	Histidine kinase
FOC75_RS21850	COG2267	carboxylic ester hydrolase activity
FOC75_RS21855	COG1368	sulfuric ester hydrolase activity
FOC75_RS21870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOC75_RS21875	COG1116	anion transmembrane transporter activity
FOC75_RS21880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC75_RS21895	COG0546	phosphoglycolate phosphatase activity
FOC75_RS21905	COG0494	nUDIX hydrolase
FOC75_RS21940	COG0288	reversible hydration of carbon dioxide
FOC75_RS21945	COG1271	oxidase subunit
FOC75_RS21950	COG1294	oxidase, subunit
FOC75_RS21970	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS21995	COG1842	Phage shock protein A
FOC75_RS22035	COG5002	protein histidine kinase activity
FOC75_RS22040	COG0745	RESPONSE REGULATOR receiver
FOC75_RS22070	COG1597	lipid kinase activity
FOC75_RS22095	COG0586	Pfam SNARE associated Golgi protein
FOC75_RS22105	COG0577	efflux transmembrane transporter activity
FOC75_RS22110	COG1136	(ABC) transporter
FOC75_RS22115	COG3708	Transcriptional regulator
FOC75_RS22115	COG2207	Transcriptional regulator
FOC75_RS22120	COG0745	RESPONSE REGULATOR receiver
FOC75_RS22125	COG2205	protein histidine kinase activity
FOC75_RS22130	COG0577	efflux transmembrane transporter activity
FOC75_RS22135	COG0577	efflux transmembrane transporter activity
FOC75_RS22140	COG1136	(ABC) transporter
FOC75_RS22145	COG0577	efflux transmembrane transporter activity
FOC75_RS22160	COG2188	Transcriptional regulator
FOC75_RS22180	COG3964	amidohydrolase
FOC75_RS22210	COG4948	Mandelate Racemase Muconate Lactonizing
FOC75_RS22220	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC75_RS22225	COG0596	Alpha beta hydrolase
FOC75_RS22235	COG1169	isochorismate synthase
FOC75_RS22240	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC75_RS22245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOC75_RS22265	COG0058	SHG alpha-glucan phosphorylase activity
FOC75_RS22275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOC75_RS22310	COG1595	DNA-templated transcription, initiation
FOC75_RS22405	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC75_RS22440	COG1285	pathogenesis
FOC75_RS22445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC75_RS22460	COG2155	Conserved Protein
FOC75_RS22465	COG1098	S1 RNA binding domain
FOC75_RS22470	COG0436	Aminotransferase
FOC75_RS22475	COG1522	sequence-specific DNA binding
FOC75_RS22480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC75_RS22485	COG2267	carboxylic ester hydrolase activity
FOC75_RS22495	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC75_RS22515	COG5018	Exonuclease
FOC75_RS22520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC75_RS22540	COG2050	protein possibly involved in aromatic compounds catabolism
FOC75_RS22550	COG1268	BioY protein
FOC75_RS22555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOC75_RS22560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC75_RS22575	COG3584	3D domain protein
FOC75_RS22595	COG1252	NADH dehydrogenase
FOC75_RS22610	COG3708	Transcriptional regulator
FOC75_RS22625	COG1683	Conserved Protein
FOC75_RS22635	COG0316	Belongs to the HesB IscA family
FOC75_RS22650	COG1252	NADH dehydrogenase
FOC75_RS22660	COG2274	protein secretion by the type I secretion system
FOC75_RS22665	COG0390	transport system, permease component
FOC75_RS22670	COG2824	Alkylphosphonate utilization operon protein PhnA
FOC75_RS22690	COG4837	Protein of unknown function (DUF1462)
FOC75_RS22695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FOC75_RS22705	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FOC75_RS22710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC75_RS22720	COG2249	NAD(P)H dehydrogenase (quinone) activity
FOC75_RS22730	COG0647	UMP catabolic process
FOC75_RS22740	COG2445	Protein of unknown function DUF86
FOC75_RS22745	COG1494	fructose-1,6-bisphosphatase
FOC75_RS22760	COG4470	Protein conserved in bacteria
FOC75_RS22770	COG0789	Transcriptional regulator
FOC75_RS22775	COG4377	Putative membrane peptidase family (DUF2324)
FOC75_RS22800	COG0739	heme binding
FOC75_RS22810	COG3377	Domain of unknown function (DUF1805)
FOC75_RS22815	COG0737	Belongs to the 5'-nucleotidase family
FOC75_RS22820	COG0719	Fe-S assembly protein
FOC75_RS22825	COG0822	iron-sulfur transferase activity
FOC75_RS22830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC75_RS22835	COG0719	Fe-S assembly protein
FOC75_RS22840	COG0396	ATPase activity
FOC75_RS22845	COG1464	Belongs to the NlpA lipoprotein family
FOC75_RS22850	COG1464	Belongs to the NlpA lipoprotein family
FOC75_RS22855	COG2011	ABC-type metal ion transport system permease component
FOC75_RS22870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC75_RS22875	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC75_RS22885	COG1393	Belongs to the ArsC family
FOC75_RS22955	COG1396	sequence-specific DNA binding
FOC75_RS22960	COG1309	transcriptional regulator
FOC75_RS22965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC75_RS22970	COG1960	acyl-CoA dehydrogenase activity
FOC75_RS22980	COG0183	Belongs to the thiolase family
FOC75_RS22985	COG1024	Enoyl-CoA hydratase
FOC75_RS22985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC75_RS22995	COG1686	Belongs to the peptidase S11 family
FOC75_RS23010	COG0011	TIGRFAM Protein of
FOC75_RS23015	COG0840	transmembrane signaling receptor activity
FOC75_RS23035	COG2814	Major facilitator Superfamily
FOC75_RS23040	COG0531	amino acid
FOC75_RS23050	COG0706	membrane insertase activity
FOC75_RS23060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS23095	COG0586	Pfam SNARE associated Golgi protein
FOC75_RS23105	COG1376	ErfK ybiS ycfS ynhG family protein
FOC75_RS23110	COG0745	RESPONSE REGULATOR receiver
FOC75_RS23115	COG5002	protein histidine kinase activity
FOC75_RS23140	COG0840	transmembrane signaling receptor activity
FOC75_RS23145	COG2151	metal-sulfur cluster biosynthetic enzyme
FOC75_RS23150	COG3227	Zinc metalloprotease (Elastase)
FOC75_RS23155	COG1741	Belongs to the pirin family
FOC75_RS23170	COG0475	glutathione-regulated potassium exporter activity
FOC75_RS23175	COG0490	domain, Protein
FOC75_RS23180	COG1115	amino acid carrier protein
FOC75_RS23185	COG0783	Belongs to the Dps family
FOC75_RS23200	COG1611	Belongs to the LOG family
FOC75_RS23220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS23225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS23230	COG1115	amino acid carrier protein
FOC75_RS23235	COG2910	NAD(P)H-binding
FOC75_RS23255	COG0656	L-ascorbic acid biosynthetic process
FOC75_RS23260	COG2814	Major facilitator Superfamily
FOC75_RS23265	COG1733	regulation of RNA biosynthetic process
FOC75_RS23275	COG1252	NADH dehydrogenase
FOC75_RS23280	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC75_RS23285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC75_RS23310	COG0840	transmembrane signaling receptor activity
FOC75_RS23310	COG3290	protein histidine kinase activity
FOC75_RS23340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC75_RS23400	COG0557	exoribonuclease II activity
FOC75_RS23405	COG1647	Serine aminopeptidase, S33
FOC75_RS23410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC75_RS23415	COG1346	cytolysis
FOC75_RS23450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC75_RS23465	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOC75_RS23490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS23505	COG2323	membrane
FOC75_RS23515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOC75_RS23525	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FOC75_RS23535	COG1051	belongs to the nudix hydrolase family
FOC75_RS23545	COG0492	ferredoxin-NADP+ reductase activity
FOC75_RS23550	COG0457	Tetratricopeptide repeat
FOC75_RS23555	COG0110	maltose O-acetyltransferase activity
FOC75_RS23575	COG1950	PFAM Membrane protein of
FOC75_RS23585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOC75_RS23590	COG0556	nucleotide-excision repair
FOC75_RS23605	COG0789	Transcriptional regulator
FOC75_RS23635	COG2855	membrane
FOC75_RS23640	COG0583	DNA-binding transcription factor activity
FOC75_RS23650	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC75_RS23665	COG1132	(ABC) transporter
FOC75_RS23670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC75_RS23675	COG3409	Peptidoglycan-binding domain 1 protein
FOC75_RS23675	COG0793	Belongs to the peptidase S41A family
FOC75_RS23680	COG2177	Part of the ABC transporter FtsEX involved in
FOC75_RS23685	COG2884	Cell division ATP-binding protein ftsE
FOC75_RS23705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC75_RS23710	COG1278	Cold shock
FOC75_RS23715	COG1040	competence protein
FOC75_RS23720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FOC75_RS23725	COG1388	LysM domain
FOC75_RS23725	COG0791	NLP P60 protein
FOC75_RS23730	COG1733	regulation of RNA biosynthetic process
FOC75_RS23735	COG1307	EDD domain protein, DegV family
FOC75_RS23740	COG1739	Uncharacterized protein family UPF0029
FOC75_RS23745	COG1316	TRANSCRIPTIONal
FOC75_RS23750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC75_RS23755	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC75_RS23760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC75_RS23770	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FOC75_RS23770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FOC75_RS23790	COG1486	melibiose metabolic process
FOC75_RS23795	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC75_RS23800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC75_RS23810	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOC75_RS23820	COG1447	Phosphotransferase system cellobiose-specific component IIA
FOC75_RS23830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FOC75_RS23835	COG1301	dicarboxylic acid transport
FOC75_RS23845	COG0346	lactoylglutathione lyase activity
FOC75_RS23850	COG1511	domain protein
FOC75_RS23855	COG0583	DNA-binding transcription factor activity
FOC75_RS23860	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOC75_RS23870	COG1271	oxidase subunit
FOC75_RS23875	COG1294	oxidase, subunit
FOC75_RS23880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOC75_RS23910	COG1620	l-lactate permease
FOC75_RS23920	COG2389	metal-binding protein
FOC75_RS23930	COG1368	sulfuric ester hydrolase activity
FOC75_RS23940	COG1388	LysM domain
FOC75_RS23940	COG0791	NLP P60 protein
FOC75_RS23945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS23955	COG1215	transferase activity, transferring glycosyl groups
FOC75_RS23960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC75_RS23965	COG3584	3D domain protein
FOC75_RS23965	COG1388	LysM domain
FOC75_RS23990	COG4715	Zinc finger, swim domain protein
FOC75_RS23995	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOC75_RS24040	COG0577	efflux transmembrane transporter activity
FOC75_RS24045	COG1136	(ABC) transporter
FOC75_RS24070	COG5002	protein histidine kinase activity
FOC75_RS24075	COG0745	RESPONSE REGULATOR receiver
FOC75_RS24080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC75_RS24095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC75_RS24100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC75_RS24100	COG1215	transferase activity, transferring glycosyl groups
FOC75_RS24105	COG1134	teichoic acid transport
FOC75_RS24110	COG1682	transport, permease protein
FOC75_RS24115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC75_RS24120	COG0463	Glycosyl transferase, family 2
FOC75_RS24120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC75_RS24125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FOC75_RS24130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC75_RS24140	COG1609	Transcriptional regulator
FOC75_RS24145	COG1649	PFAM Uncharacterised BCR, COG1649
FOC75_RS24145	COG0726	polysaccharide deacetylase
FOC75_RS24155	COG0739	heme binding
FOC75_RS24170	COG3279	Response regulator of the LytR AlgR family
FOC75_RS24175	COG2385	sporulation resulting in formation of a cellular spore
FOC75_RS24190	COG4836	Membrane
FOC75_RS24195	COG1007	ATP synthesis coupled electron transport
FOC75_RS24200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC75_RS24205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC75_RS24215	COG0839	Belongs to the complex I subunit 6 family
FOC75_RS24235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC75_RS24250	COG5001	Diguanylate cyclase
FOC75_RS24250	COG3300	MHYT domain
FOC75_RS24300	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC75_RS24335	COG0698	ribose 5-phosphate isomerase
FOC75_RS24345	COG2190	(PTS) system
FOC75_RS24350	COG2259	Doxx family
FOC75_RS24355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOC75_RS24370	COG0009	L-threonylcarbamoyladenylate synthase
FOC75_RS24385	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC75_RS24405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOC75_RS24410	COG1494	fructose-1,6-bisphosphatase
FOC75_RS24430	COG4821	SIS domain
FOC75_RS24450	COG1960	acyl-CoA dehydrogenase activity
FOC75_RS24455	COG1960	acyl-CoA dehydrogenase activity
FOC75_RS24460	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOC75_RS24465	COG0183	Belongs to the thiolase family
FOC75_RS24470	COG0247	lactate metabolic process
FOC75_RS24470	COG2181	nitrate reductase activity
FOC75_RS24475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC75_RS24485	COG3300	MHYT domain
FOC75_RS24485	COG5001	Diguanylate cyclase
FOC75_RS24515	COG0024	Methionine aminopeptidase
FOC75_RS24525	COG2234	aminopeptidase activity
FOC75_RS24545	COG1595	DNA-templated transcription, initiation
FOC75_RS24555	COG4506	Protein conserved in bacteria
FOC75_RS24560	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC75_RS24575	COG0010	Belongs to the arginase family
FOC75_RS24585	COG2814	Major facilitator Superfamily
FOC75_RS24590	COG0789	Transcriptional regulator
FOC75_RS24595	COG0584	glycerophosphoryl diester phosphodiesterase
FOC75_RS24600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC75_RS24610	COG1994	Peptidase M50
FOC75_RS24620	COG1078	dGTPase activity
FOC75_RS24625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS24630	COG1120	ATPase activity
FOC75_RS24635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS24640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS24660	COG0095	Lipoate-protein ligase
FOC75_RS24670	COG0280	phosphate acetyltransferase
FOC75_RS24685	COG3773	Cell wall hydrolase
FOC75_RS24695	COG2363	Small membrane protein
FOC75_RS24705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC75_RS24710	COG2233	PERMEase
FOC75_RS24715	COG0561	phosphatase activity
FOC75_RS24720	COG2814	Major facilitator Superfamily
FOC75_RS24730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FOC75_RS24735	COG1131	(ABC) transporter
FOC75_RS24740	COG2755	lipolytic protein G-D-S-L family
FOC75_RS24745	COG1609	Transcriptional regulator
FOC75_RS24755	COG0460	homoserine dehydrogenase
FOC75_RS24765	COG2873	o-acetylhomoserine
FOC75_RS24775	COG1011	Hydrolase
FOC75_RS24780	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC75_RS24790	COG2197	response regulator
FOC75_RS24795	COG4585	Histidine kinase
FOC75_RS24795	COG2203	Gaf domain
FOC75_RS24800	COG0351	phosphomethylpyrimidine kinase
FOC75_RS24805	COG3706	GGDEF domain
FOC75_RS24810	COG2879	small protein
FOC75_RS24815	COG1966	Carbon starvation protein
FOC75_RS24820	COG3279	Response regulator of the LytR AlgR family
FOC75_RS24825	COG0477	Major facilitator Superfamily
FOC75_RS24850	COG0840	transmembrane signaling receptor activity
FOC75_RS24860	COG1607	acyl-coa hydrolase
FOC75_RS24875	COG0488	(ABC) transporter
FOC75_RS24895	COG0463	Glycosyl transferase, family 2
FOC75_RS24900	COG1309	transcriptional regulator
FOC75_RS24905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC75_RS24910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC75_RS24910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC75_RS24915	COG0628	permease
FOC75_RS24930	COG3279	Response regulator of the LytR AlgR family
FOC75_RS24935	COG3275	phosphorelay sensor kinase activity
FOC75_RS24940	COG2814	Major facilitator Superfamily
FOC75_RS24945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOC75_RS24950	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FOC75_RS24955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOC75_RS24975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC75_RS24980	COG1272	protein, Hemolysin III
FOC75_RS25005	COG1164	Oligoendopeptidase f
FOC75_RS25025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC75_RS25030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC75_RS25035	COG4853	Protein conserved in bacteria
FOC75_RS25040	COG4863	YycH protein
FOC75_RS25045	COG5002	protein histidine kinase activity
FOC75_RS25050	COG0745	RESPONSE REGULATOR receiver
FOC75_RS25080	COG0305	Participates in initiation and elongation during chromosome replication
FOC75_RS25090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FOC75_RS25095	COG4241	membrane
FOC75_RS25105	COG0629	single-stranded DNA binding
FOC75_RS25115	COG0012	GTP binding
FOC75_RS25120	COG4481	Protein conserved in bacteria
FOC75_RS25125	COG0668	transmembrane transport
FOC75_RS25135	COG1475	DNA binding
FOC75_RS25140	COG1192	Involved in chromosome partitioning
FOC75_RS25165	COG1847	R3H domain protein
FOC75_RS25170	COG0706	membrane insertase activity
FOC75_RS25180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC75_RS25190	COG0592	DNA-directed DNA polymerase activity
FOC75_RS25195	COG2501	S4 domain
FOC75_RS25205	COG0187	DNA topoisomerase II activity
FOC75_RS25210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FOC75_RS25245	COG0516	GMP reductase activity
FOC75_RS25245	COG0517	IMP dehydrogenase activity
FOC75_RS25250	COG1686	Belongs to the peptidase S11 family
FOC75_RS25280	COG1428	Deoxynucleoside kinase
FOC75_RS25285	COG1428	Deoxynucleoside kinase
FOC75_RS25290	COG1335	isochorismatase
FOC75_RS25295	COG0590	tRNA wobble adenosine to inosine editing
FOC75_RS25305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC75_RS25360	COG1982	Orn Lys Arg decarboxylase major
FOC75_RS25370	COG0470	DNA polymerase III
FOC75_RS25375	COG1774	PSP1 C-terminal conserved region
FOC75_RS25385	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC75_RS25395	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC75_RS25400	COG2002	toxin-antitoxin pair type II binding
FOC75_RS25405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC75_RS25405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC75_RS25410	COG0084	hydrolase, TatD family'
FOC75_RS25415	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FOC75_RS25430	COG4466	Protein conserved in bacteria
FOC75_RS25445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC75_RS25450	COG0251	oxidation-reduction process
FOC75_RS25480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC75_RS25485	COG2002	toxin-antitoxin pair type II binding
FOC75_RS25490	COG2244	polysaccharide biosynthetic process
FOC75_RS25495	COG3956	TIGRFAM MazG family protein
FOC75_RS25500	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC75_RS25520	COG1098	S1 RNA binding domain
FOC75_RS25535	COG2208	phosphoserine phosphatase activity
FOC75_RS25550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC75_RS25565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC75_RS25570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC75_RS25575	COG0512	Glutamine amidotransferase of anthranilate synthase
FOC75_RS25580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC75_RS25585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC75_RS25590	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC75_RS25595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC75_RS25600	COG1396	sequence-specific DNA binding
FOC75_RS25605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC75_RS25695	COG3880	PFAM UvrB UvrC protein
FOC75_RS25705	COG0542	response to heat
FOC75_RS25710	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC75_RS25720	COG4956	integral membrane protein (PIN domain superfamily)
FOC75_RS25740	COG1045	serine acetyltransferase
FOC75_RS25755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC75_RS25760	COG3688	RNA-binding protein containing a PIN domain
FOC75_RS25775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC75_RS25780	COG0250	Participates in transcription elongation, termination and antitermination
FOC75_RS25785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC75_RS25805	COG2813	Specifically methylates the guanine in position
FOC75_RS25820	COG1358	cellular component organization or biogenesis
FOC75_RS25890	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC75_RS25950	COG0201	protein transport
FOC75_RS25960	COG0024	Methionine aminopeptidase
FOC75_RS25970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC75_RS26005	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOC75_RS26030	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS26035	COG0489	protein tyrosine kinase activity
FOC75_RS26045	COG2194	sulfuric ester hydrolase activity
FOC75_RS26050	COG0726	polysaccharide deacetylase
FOC75_RS26130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC75_RS26135	COG4856	YbbR-like protein
FOC75_RS26160	COG0596	Alpha beta hydrolase
FOC75_RS26180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC75_RS26185	COG0823	Involved in the tonB-independent uptake of proteins
FOC75_RS26185	COG4946	Tricorn protease homolog
FOC75_RS26185	COG1506	peptidase
FOC75_RS26215	COG1028	Short-chain dehydrogenase reductase Sdr
FOC75_RS26220	COG2011	ABC-type metal ion transport system permease component
FOC75_RS26225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC75_RS26230	COG1464	Belongs to the NlpA lipoprotein family
FOC75_RS26235	COG0604	alcohol dehydrogenase
FOC75_RS26245	COG0277	FAD linked oxidase domain protein
FOC75_RS26250	COG2271	Major facilitator Superfamily
FOC75_RS26260	COG2814	Major facilitator Superfamily
FOC75_RS26275	COG0601	transmembrane transport
FOC75_RS26280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC75_RS26285	COG0444	Belongs to the ABC transporter superfamily
FOC75_RS26290	COG4608	Belongs to the ABC transporter superfamily
FOC75_RS26295	COG4166	transmembrane transport
FOC75_RS26305	COG2207	Transcriptional regulator
FOC75_RS26315	COG1309	transcriptional regulator
FOC75_RS26325	COG4166	transmembrane transport
FOC75_RS26330	COG4166	transmembrane transport
FOC75_RS26335	COG0656	L-ascorbic acid biosynthetic process
FOC75_RS26340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC75_RS26355	COG4149	molybdate abc transporter
FOC75_RS26360	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOC75_RS26365	COG1910	domain protein
FOC75_RS26380	COG0697	spore germination
FOC75_RS26395	COG0204	Acyl-transferase
FOC75_RS26405	COG1609	Transcriptional regulator
FOC75_RS26415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC75_RS26425	COG0084	hydrolase, TatD family'
FOC75_RS26430	COG5298	Protein conserved in bacteria
FOC75_RS26455	COG0488	(ABC) transporter
FOC75_RS26460	COG4585	Histidine kinase
FOC75_RS26465	COG2197	response regulator
FOC75_RS26470	COG1131	(ABC) transporter
FOC75_RS26475	COG1511	domain protein
FOC75_RS26475	COG0842	Transport permease protein
FOC75_RS26480	COG0842	Transport permease protein
FOC75_RS26495	COG0747	negative chemotaxis
FOC75_RS26500	COG0601	transmembrane transport
FOC75_RS26505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOC75_RS26510	COG0444	Belongs to the ABC transporter superfamily
FOC75_RS26515	COG4608	Belongs to the ABC transporter superfamily
FOC75_RS26520	COG0561	phosphatase activity
FOC75_RS26550	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FOC75_RS26555	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC75_RS26565	COG2814	Major facilitator Superfamily
FOC75_RS26575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC75_RS26585	COG4294	response to UV
FOC75_RS26590	COG0457	Tetratricopeptide repeat
FOC75_RS26590	COG0705	Rhomboid family
FOC75_RS26600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOC75_RS26605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC75_RS26610	COG0864	Transcriptional regulator
FOC75_RS26615	COG2337	Toxic component of a toxin-antitoxin (TA) module
FOC75_RS26620	COG2183	response to ionizing radiation
FOC75_RS26715	COG0802	atpase or kinase
FOC75_RS26720	COG1214	PFAM Peptidase M22, glycoprotease
FOC75_RS26725	COG0456	acetyltransferase
FOC75_RS26735	COG0488	(ABC) transporter
FOC75_RS26750	COG1266	CAAX protease self-immunity
FOC75_RS26770	COG2252	PERMEase
FOC75_RS26780	COG5002	protein histidine kinase activity
FOC75_RS26805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOC75_RS26845	COG2205	protein histidine kinase activity
FOC75_RS26850	COG0745	RESPONSE REGULATOR receiver
FOC75_RS26870	COG0697	spore germination
FOC75_RS26895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC75_RS26900	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOC75_RS26905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FOC75_RS26915	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOC75_RS26930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC75_RS26940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC75_RS26950	COG0151	Belongs to the GarS family
FOC75_RS26975	COG0210	DNA helicase
FOC75_RS26985	COG4851	CamS sex pheromone cAM373 precursor
FOC75_RS27005	COG1335	isochorismatase
FOC75_RS27010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOC75_RS27015	COG2011	ABC-type metal ion transport system permease component
FOC75_RS27020	COG1464	Belongs to the NlpA lipoprotein family
FOC75_RS27035	COG0003	Pfam Anion-transporting ATPase
FOC75_RS27040	COG1846	Transcriptional regulator
FOC75_RS27045	COG4682	membrane
FOC75_RS27065	COG1597	lipid kinase activity
FOC75_RS27070	COG0546	phosphoglycolate phosphatase activity
FOC75_RS27075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOC75_RS27085	COG1012	belongs to the aldehyde dehydrogenase family
FOC75_RS27090	COG2076	Multidrug Resistance protein
FOC75_RS27095	COG2309	aminopeptidase activity
FOC75_RS27110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FOC75_RS27115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC75_RS27120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC75_RS27130	COG4807	Protein conserved in bacteria
FOC75_RS27160	COG1473	amidohydrolase
FOC75_RS27175	COG0450	alkyl hydroperoxide reductase
FOC75_RS27195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS27200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC75_RS27205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC75_RS27220	COG0166	Belongs to the GPI family
FOC75_RS27255	COG5002	protein histidine kinase activity
FOC75_RS27275	COG3541	Predicted nucleotidyltransferase
FOC75_RS27280	COG2814	Major facilitator Superfamily
FOC75_RS27285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC75_RS27285	COG0723	plastoquinol--plastocyanin reductase activity
FOC75_RS27295	COG0765	amino acid transport
FOC75_RS27300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC75_RS27310	COG0840	transmembrane signaling receptor activity
FOC75_RS27350	COG0366	Alpha amylase catalytic
FOC75_RS27355	COG1263	PTS System
FOC75_RS27355	COG2190	(PTS) system
FOC75_RS27355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC75_RS27385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC75_RS27400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOC75_RS27410	COG1116	anion transmembrane transporter activity
FOC75_RS27415	COG0488	(ABC) transporter
FOC75_RS27465	COG2270	Major facilitator Superfamily
FOC75_RS27495	COG2310	stress, protein
FOC75_RS27500	COG2310	stress, protein
FOC75_RS27505	COG2310	stress, protein
FOC75_RS27510	COG0861	Integral membrane protein TerC family
FOC75_RS27520	COG3853	Toxic anion resistance protein (TelA)
FOC75_RS27535	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC75_RS27545	COG1295	ribonuclease BN
FOC75_RS27550	COG2217	Heavy metal translocating P-type atpase
FOC75_RS27555	COG0697	spore germination
FOC75_RS27580	COG0586	Pfam SNARE associated Golgi protein
FOC75_RS27595	COG3871	stress protein (general stress protein 26)
FOC75_RS27600	COG0387	Pfam Sodium calcium exchanger
FOC75_RS27610	COG0535	radical SAM domain protein
FOC75_RS27630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FOC75_RS27635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC75_RS27650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC75_RS27680	COG1263	PTS System
FOC75_RS27680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FOC75_RS27685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FOC75_RS27700	COG0463	Glycosyl transferase, family 2
FOC75_RS27710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC75_RS27710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC75_RS27730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC75_RS27825	COG3118	belongs to the thioredoxin family
FOC75_RS27845	COG1126	abc transporter atp-binding protein
FOC75_RS27850	COG2304	oxidoreductase activity
FOC75_RS27855	COG2132	Multicopper oxidase
FOC75_RS27860	COG0745	RESPONSE REGULATOR receiver
FOC75_RS27865	COG5002	protein histidine kinase activity
FOC75_RS27875	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS27930	COG2918	glutathione biosynthetic process
FOC75_RS27930	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOC75_RS27940	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FOC75_RS27950	COG1733	regulation of RNA biosynthetic process
FOC75_RS27965	COG0697	spore germination
FOC75_RS27990	COG2323	membrane
FOC75_RS28005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC75_RS28040	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC75_RS28080	COG3708	Transcriptional regulator
FOC75_RS28080	COG2207	Transcriptional regulator
FOC75_RS28100	COG1335	isochorismatase
FOC75_RS28130	COG0546	phosphoglycolate phosphatase activity
FOC75_RS28170	COG3344	reverse transcriptase
FOC75_RS28190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC75_RS28240	COG1780	Probably involved in ribonucleotide reductase function
FOC75_RS28395	COG1466	dna polymerase III delta subunit
FOC75_RS28405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC75_RS28420	COG3344	reverse transcriptase
FOC75_RS28450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC75_RS28545	COG3344	reverse transcriptase
FOC75_RS28565	COG0791	NLP P60 protein
FOC75_RS28565	COG0741	lytic transglycosylase activity
FOC75_RS28600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC75_RS28670	COG2318	DinB family
FOC75_RS28830	COG1674	ftsk spoiiie
FOC75_RS28875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC75_RS28885	COG0210	DNA helicase
FOC75_RS28890	COG0470	DNA polymerase III
FOC75_RS28910	COG2304	oxidoreductase activity
FOC75_RS28915	COG2002	toxin-antitoxin pair type II binding
FOC75_RS28985	COG0798	PFAM Bile acid sodium symporter
FOC75_RS28990	COG0640	Transcriptional regulator
FOC75_RS29005	COG0523	cobalamin synthesis protein
FOC75_RS29010	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC75_RS29020	COG3620	sequence-specific DNA binding
FOC75_RS29025	COG0306	phosphate transporter
FOC75_RS29030	COG0640	Transcriptional regulator
FOC75_RS29045	COG1846	Transcriptional regulator
FOC75_RS29085	COG2217	Heavy metal translocating P-type atpase
FOC75_RS29090	COG1937	Protein conserved in bacteria
FOC75_RS29095	COG0803	Belongs to the bacterial solute-binding protein 9 family
FOC75_RS29095	COG3443	Belongs to the bacterial solute-binding protein 9 family
FOC75_RS29115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins