locus-tag class description FOC91_RS00100 ENOG4105D7V transposase FOC91_RS00130 ENOG4105CNU cell division protein FtsK FOC91_RS00135 ENOG4105EKQ RNA-directed DNA polymerase FOC91_RS00190 ENOG4105EKQ RNA-directed DNA polymerase FOC91_RS00250 ENOG4105EKQ RNA-directed DNA polymerase FOC91_RS00410 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC91_RS00450 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC91_RS00570 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC91_RS00585 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC91_RS00625 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC91_RS00640 ENOG4105KRN Transcriptional regulator, abrb family FOC91_RS00695 ENOG4105K70 DNA-binding protein FOC91_RS00725 ENOG4105DHF Membrane FOC91_RS00755 ENOG41086D8 Transcriptional regulator FOC91_RS00925 ENOG4105C3M thioredoxin reductase FOC91_RS00945 ENOG4105D6J arsenicaL-resistance protein FOC91_RS00950 ENOG41082YX Transcriptional regulator, arsr family FOC91_RS00985 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC91_RS01000 ENOG4105CHH sulfate transporter FOC91_RS01020 ENOG4105CHH sulfate transporter FOC91_RS01025 ENOG4107YZX Universal stress protein FOC91_RS01030 ENOG4105CN5 Metallo-Beta-Lactamase FOC91_RS01040 ENOG4105H3G oxidoreductase FOC91_RS01045 ENOG4105CAY ferredoxin--nadp reductase FOC91_RS01050 ENOG41085FC arsR family transcriptional regulator FOC91_RS01165 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS01215 ENOG4105CFF transcriptional regulator FOC91_RS01285 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC91_RS01360 ENOG4105CAR Terminase, large subunit FOC91_RS01435 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS01485 ENOG4105CFF transcriptional regulator FOC91_RS01520 ENOG4106032 Glutathionylspermidine synthase FOC91_RS01550 ENOG4105KHC sulfurtransferase FOC91_RS01560 ENOG4108W0I acetyltransferase FOC91_RS01570 ENOG410890F Dynamin family FOC91_RS01575 ENOG4105DHF Membrane FOC91_RS01580 ENOG4105C2W permease FOC91_RS01590 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC91_RS01605 ENOG4105CTD carboxy-peptidase FOC91_RS01610 ENOG4105DVT helicase FOC91_RS01620 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC91_RS01680 ENOG4105BZ4 penicillin-binding protein FOC91_RS01690 ENOG4105CSM endonuclease III FOC91_RS01710 ENOG4105YAC FOC91_RS01715 ENOG4105DVT helicase FOC91_RS01750 ENOG4105CPK Glycosyl transferase (Group 1 FOC91_RS01755 ENOG4105FJR Lmbe family FOC91_RS01770 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC91_RS01775 ENOG4108JYZ YitT family FOC91_RS01805 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit FOC91_RS01810 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC91_RS01815 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC91_RS01830 ENOG41068YB TPR repeat-containing protein FOC91_RS01835 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC91_RS01855 ENOG4105EAH synthase FOC91_RS01865 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC91_RS01880 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC91_RS01910 ENOG41065D1 FOC91_RS01915 ENOG4105S2F FOC91_RS01950 ENOG4105HDK L-asparaginase FOC91_RS01955 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC91_RS01980 ENOG4108S6Z Negative regulator of genetic competence FOC91_RS01985 ENOG4107X2D transcriptional regulator, merr family FOC91_RS01990 ENOG4107RGJ metallophosphoesterase FOC91_RS02000 ENOG4105I7S Abortive infection protein FOC91_RS02005 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC91_RS02020 ENOG4108SAX Membrane FOC91_RS02030 ENOG41063SB peptidase FOC91_RS02035 ENOG4108WBT adenosyltransferase FOC91_RS02040 ENOG4105BZU Histidine kinase FOC91_RS02045 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS02050 ENOG4105CRE cytochrome C FOC91_RS02055 ENOG4107TWT Cytochrome c biogenesis protein FOC91_RS02065 ENOG4105FE9 pseudouridine synthase FOC91_RS02075 ENOG4108JIC nucleoside recognition domain protein FOC91_RS02080 ENOG4105DZ1 carboxypeptidase FOC91_RS02085 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC91_RS02120 ENOG4105BZU Histidine kinase FOC91_RS02135 ENOG4105I3N Conserved Protein FOC91_RS02140 ENOG4105BZU Histidine kinase FOC91_RS02155 ENOG4105BZ4 penicillin-binding protein FOC91_RS02160 ENOG4107GRR phosphate transport regulator FOC91_RS02165 ENOG4105CJ3 phosphate transporter FOC91_RS02210 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) FOC91_RS02230 ENOG4105WH1 Two component transcriptional regulator luxr family FOC91_RS02235 ENOG4105ENE Histidine kinase FOC91_RS02255 ENOG4105DFD Na H antiporter FOC91_RS02275 ENOG4105C8J )-transporter FOC91_RS02280 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC91_RS02285 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC91_RS02290 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC91_RS02300 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC91_RS02305 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC91_RS02325 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC91_RS02335 ENOG4105E0M Sulfatase FOC91_RS02340 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC91_RS02345 ENOG4105C5I Dehydrogenase FOC91_RS02355 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC91_RS02430 ENOG4108ZP8 Acetolactate synthase small subunit FOC91_RS02435 ENOG4105C7K acetolactate synthase FOC91_RS02440 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC91_RS02465 ENOG4105KBJ sporulation protein ytfj FOC91_RS02470 ENOG41063Y9 FOC91_RS02475 ENOG4105CZN Potassium uptake protein FOC91_RS02505 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC91_RS02510 ENOG4107QMU Mate efflux family protein FOC91_RS02545 ENOG4105NQC Flavodoxin FOC91_RS02570 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC91_RS02580 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC91_RS02585 ENOG4105EA8 2-Nitropropane dioxygenase FOC91_RS02590 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC91_RS02630 ENOG4105CJ1 ABC, transporter FOC91_RS02640 ENOG4105CZV ABC transporter FOC91_RS02645 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS02650 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC91_RS02660 ENOG41079K6 HNH endonuclease FOC91_RS02665 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC91_RS02670 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC91_RS02710 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC91_RS02715 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC91_RS02725 ENOG4105BZU Histidine kinase FOC91_RS02730 ENOG4106DF1 FOC91_RS02740 ENOG41090MY MarR family Transcriptional regulator FOC91_RS02745 ENOG4105BZU Histidine kinase FOC91_RS02755 ENOG4105PXI polysaccharide deacetylase FOC91_RS02765 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FOC91_RS02775 ENOG4105E98 transcriptional regulator DeoR family FOC91_RS02795 ENOG4107RCV ABC transporter, permease FOC91_RS02800 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC91_RS02805 ENOG4105C4Y ABC transporter FOC91_RS02825 ENOG4105MWK D-amino acid dehydrogenase, small subunit FOC91_RS02835 ENOG4105CHR reductase FOC91_RS02855 ENOG4108Z7G MaoC domain protein dehydratase FOC91_RS02860 ENOG410681C small acid-soluble spore protein FOC91_RS02865 ENOG4105CZN Potassium uptake protein FOC91_RS02870 ENOG4107TS3 membrane protein, TerC FOC91_RS02875 ENOG4108QTI )-transporter FOC91_RS02885 ENOG4106A3R peptidase FOC91_RS02905 ENOG4105JXH GntR family transcriptional regulator FOC91_RS02910 ENOG4105BZU Histidine kinase FOC91_RS02915 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS02930 ENOG4105CQB FAD linked oxidase domain protein FOC91_RS02935 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC91_RS02940 ENOG4105K4I Scp-like extracellular FOC91_RS02950 ENOG4108YBP pseudouridine synthase FOC91_RS02960 ENOG4105EYF MMPL domain protein FOC91_RS02970 ENOG4107RUE extracellular solute-binding protein family 1 FOC91_RS02975 ENOG4105D38 putrescine abc transporter FOC91_RS02980 ENOG4105F38 ABC transporter, permease FOC91_RS02990 ENOG4105C26 Dehydrogenase FOC91_RS03025 ENOG4105VFR signal peptidase FOC91_RS03030 ENOG4105DZ1 carboxypeptidase FOC91_RS03055 ENOG41069I7 FOC91_RS03120 ENOG4105VZ8 Transcriptional regulator FOC91_RS03130 ENOG4105C7S Dehydrogenase FOC91_RS03150 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC91_RS03230 ENOG4105DDQ anthranilate synthase FOC91_RS03240 ENOG4105CK7 Sodium proline symporter FOC91_RS03335 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC91_RS03340 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC91_RS03360 ENOG4107TVC Glycosyl transferase, family 2 FOC91_RS03380 ENOG4105K64 Glycosyl transferase, family 2 FOC91_RS03400 ENOG4105EMS pseudouridine synthase FOC91_RS03420 ENOG4105MIX Adenylate cyclase FOC91_RS03425 ENOG4108Z18 K06886 hemoglobin FOC91_RS03440 ENOG4105DPN Oligoendopeptidase f FOC91_RS03450 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC91_RS03460 ENOG4108ZCF integral membrane protein FOC91_RS03480 ENOG4105UQX Mate efflux family protein FOC91_RS03485 ENOG4108JQ7 (ABC) transporter FOC91_RS03495 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC91_RS03500 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC91_RS03515 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC91_RS03530 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC91_RS03535 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC91_RS03560 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOC91_RS03570 ENOG4108KP7 hydrolase FOC91_RS03580 ENOG41073B9 FOC91_RS03585 ENOG4107AYK membrAne FOC91_RS03595 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC91_RS03605 ENOG4105QNR S1 RNA binding domain protein FOC91_RS03625 ENOG4105BZU Histidine kinase FOC91_RS03630 ENOG4105CH6 catalase FOC91_RS03635 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FOC91_RS03640 ENOG4105CAQ asparagine synthetase FOC91_RS03665 ENOG4105ERH Fumarylacetoacetate hydrolase FOC91_RS03730 ENOG4105XVF Competence transcription factor FOC91_RS03760 ENOG4107QP3 malate synthase g FOC91_RS03785 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC91_RS03810 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS03820 ENOG41086D8 Transcriptional regulator FOC91_RS03825 ENOG4108AEY RNA polymerase sigma factor FOC91_RS03835 ENOG4107TVP HD domain protein FOC91_RS03845 ENOG4107RN3 metallophosphoesterase FOC91_RS03850 ENOG4105ENX hydrolase FOC91_RS03910 ENOG4105CEY Amp-dependent synthetase and ligase FOC91_RS03920 ENOG4105DF9 Lipoate-protein, ligase FOC91_RS03925 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC91_RS03930 ENOG4106AXD FOC91_RS03960 ENOG4105ECB domain protein FOC91_RS03975 ENOG4105NA0 Transcriptional regulator FOC91_RS04000 ENOG4105C1Q protoporphyrinogen oxidase FOC91_RS04015 ENOG4105BZ4 penicillin-binding protein FOC91_RS04020 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC91_RS04025 ENOG4105CKV Membrane FOC91_RS04030 ENOG410905X membrane-flanked domain protein FOC91_RS04080 ENOG4105CKV Membrane FOC91_RS04085 ENOG410905X membrane-flanked domain protein FOC91_RS04170 ENOG4105K59 histidine triad (HIT) protein FOC91_RS04195 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC91_RS04200 ENOG4105EEM helicase FOC91_RS04210 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC91_RS04215 ENOG4105C57 major facilitator superfamily FOC91_RS04240 ENOG4105EMN RNA polymerase sigma factor FOC91_RS04260 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC91_RS04275 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC91_RS04295 ENOG4108MUZ hydrolase FOC91_RS04350 ENOG4106D4I domain protein FOC91_RS04355 ENOG4107VRP DNA repair exonuclease FOC91_RS04380 ENOG4108VB1 regulatoR FOC91_RS04385 ENOG4105ENE Histidine kinase FOC91_RS04425 ENOG4105BZU Histidine kinase FOC91_RS04430 ENOG4105BZU Histidine kinase FOC91_RS04435 ENOG4108MJI response regulator FOC91_RS04445 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS04455 ENOG4105WN5 stage II sporulation protein FOC91_RS04520 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC91_RS04530 ENOG410780I phosphoprotein phosphatase activity FOC91_RS04545 ENOG410847I Transcriptional regulator, BadM Rrf2 family FOC91_RS04550 ENOG4107YCK Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FOC91_RS04555 ENOG4105CMT Dihydroxyacetone kinase FOC91_RS04565 ENOG4105CMT Dihydroxyacetone kinase FOC91_RS04570 ENOG4108NIW Leucine export protein LeuE FOC91_RS04625 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC91_RS04640 ENOG4108IG5 Transcriptional regulator FOC91_RS04645 ENOG4107P5I polyketide synthase FOC91_RS04730 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 FOC91_RS04740 ENOG4105CDU Replicative dna helicase FOC91_RS04800 ENOG4108MRH transcriptional regulatory protein FOC91_RS04810 ENOG4105CSH Transporter FOC91_RS04830 ENOG4105CTU Proline racemase FOC91_RS04850 ENOG4105DER m42 family FOC91_RS04870 ENOG4105CGU Enoyl-CoA hydratase FOC91_RS04880 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC91_RS04890 ENOG4106AKK s-layer domain-containing protein FOC91_RS04935 ENOG4105CHH sulfate transporter FOC91_RS04950 ENOG4105D4P Coproporphyrinogen iii oxidase FOC91_RS04955 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC91_RS04970 ENOG4107FQX Alpha-acetolactate decarboxylase FOC91_RS05020 ENOG4105BZU Histidine kinase FOC91_RS05045 ENOG410839P FOC91_RS05060 ENOG4105CDA abc transporter atp-binding protein FOC91_RS05065 ENOG4105DRP amino acid AbC transporter FOC91_RS05075 ENOG4105BZ1 (ABC) transporter FOC91_RS05080 ENOG4105BZ1 (ABC) transporter FOC91_RS05085 ENOG4105C26 Dehydrogenase FOC91_RS05095 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC91_RS05100 ENOG4105D5Q Arginine ornithine antiporter FOC91_RS05110 ENOG4105CH6 catalase FOC91_RS05115 ENOG4107RKG DJ-1/PfpI family FOC91_RS05125 ENOG4105E5W Transporter FOC91_RS05130 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC91_RS05145 ENOG4105KPY Small multidrug resistance protein FOC91_RS05160 ENOG4108YXU transcriptional regulator AsnC family FOC91_RS05205 ENOG4106KNT transcriptional regulator FOC91_RS05215 ENOG4107RWR Sodium hydrogen exchanger FOC91_RS05220 ENOG4105CUB amino acid FOC91_RS05255 ENOG4107T5V SNARE associated Golgi FOC91_RS05290 ENOG4105WEF catalase FOC91_RS05325 ENOG4105C19 ABC transporter FOC91_RS05330 ENOG4107RBB ABC transporter, permease FOC91_RS05335 ENOG41069ER domain protein FOC91_RS05355 ENOG4105VZJ PTS System FOC91_RS05360 ENOG4105VCP PTS System FOC91_RS05365 ENOG4105EMD TRANSCRIPTIONal FOC91_RS05390 ENOG4108KGH TRANSCRIPTIONal FOC91_RS05400 ENOG41087NI Sulfite exporter TauE/SafE FOC91_RS05405 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC91_RS05415 ENOG41085GJ domain protein FOC91_RS05420 ENOG4105VFE sira family FOC91_RS05425 ENOG4107TPS domain protein FOC91_RS05430 ENOG4105VFE sira family FOC91_RS05435 ENOG4105XTG Pfam:DUF156 FOC91_RS05440 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC91_RS05485 ENOG4105ED1 spovr family FOC91_RS05490 ENOG4107Y03 Nitroreductase FOC91_RS05510 ENOG4108B31 Spore germination protein FOC91_RS05545 ENOG4105C5Y PTS System FOC91_RS05565 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC91_RS05575 ENOG4105C7N Xanthine uracil vitamin C permease FOC91_RS05585 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC91_RS05610 ENOG4108INS Transcriptional regulator FOC91_RS05660 ENOG4105DWF phosphomethylpyrimidine kinase FOC91_RS05665 ENOG4105D06 uba thif-type nad fad binding protein FOC91_RS05680 ENOG41080HI glycine oxidase FOC91_RS05685 ENOG4108VEU Thiamine monophosphate synthase FOC91_RS05695 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC91_RS05705 ENOG4105ETU transcriptional activator (TenA FOC91_RS05725 ENOG41080XQ Signal transduction protein with cbs domains FOC91_RS05855 ENOG4105E2Z phosphate ABC transporter (Permease FOC91_RS05860 ENOG4105C8U phosphate abc transporter FOC91_RS05865 ENOG4105CVA phosphate FOC91_RS05870 ENOG4105CE1 Ferrous iron transport protein b FOC91_RS05875 ENOG4105CE1 Ferrous iron transport protein b FOC91_RS05880 ENOG4105CE1 Ferrous iron transport protein b FOC91_RS05885 ENOG4108NHD germination protein FOC91_RS05900 ENOG4105E1V na solute symporter FOC91_RS05905 ENOG4106CAD Protein of unknown function (DUF3311) FOC91_RS05920 ENOG4105E2S oxidase) subunit II FOC91_RS05925 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC91_RS05950 ENOG4105MA6 gCN5-related N-acetyltransferase FOC91_RS05965 ENOG4105C7N Xanthine uracil vitamin C permease FOC91_RS05970 ENOG4105C85 amino acid FOC91_RS05990 ENOG4105DUX Transporter FOC91_RS06000 ENOG4107D63 FOC91_RS06005 ENOG4105VZ8 Transcriptional regulator FOC91_RS06010 ENOG41069ER domain protein FOC91_RS06015 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC91_RS06080 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC91_RS06085 ENOG4105CNN ABC, transporter FOC91_RS06100 ENOG4108RVA ribokinase FOC91_RS06105 ENOG4105ETE Transcriptional regulator (LacI family FOC91_RS06110 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC91_RS06115 ENOG41067TZ transcriptional regulator, MarR family FOC91_RS06120 ENOG4105CXY transporter FOC91_RS06130 ENOG4108JQ7 (ABC) transporter FOC91_RS06135 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC91_RS06145 ENOG4105DEF Extracellular solute-binding protein, family 5 FOC91_RS06155 ENOG41068KF Universal stress protein FOC91_RS06160 ENOG4105CHH sulfate transporter FOC91_RS06170 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS06175 ENOG4105BZU Histidine kinase FOC91_RS06180 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC91_RS06185 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC91_RS06210 ENOG4108IQI permease FOC91_RS06215 ENOG4105DRP amino acid AbC transporter FOC91_RS06220 ENOG4105EAD ABC transporter FOC91_RS06225 ENOG4105CT1 (ABC) transporter FOC91_RS06230 ENOG4105CDA abc transporter atp-binding protein FOC91_RS06235 ENOG4105BZG amino acid carrier protein FOC91_RS06240 ENOG4105CRN Aminoglycoside phosphotransferase FOC91_RS06255 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC91_RS06260 ENOG4105WH1 Two component transcriptional regulator luxr family FOC91_RS06265 ENOG4108XG2 Histidine kinase FOC91_RS06270 ENOG4105E1K spore germination protein FOC91_RS06285 ENOG4105CG3 alpha amylase, catalytic region FOC91_RS06290 ENOG4105C5Y PTS System FOC91_RS06295 ENOG4107414 GntR family transcriptional regulator FOC91_RS06300 ENOG4105D5Q Arginine ornithine antiporter FOC91_RS06305 ENOG4105BZU Histidine kinase FOC91_RS06315 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC91_RS06320 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC91_RS06325 ENOG4107T89 von Willebrand factor, type A FOC91_RS06335 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) FOC91_RS06340 ENOG4105EXW epimerase dehydratase FOC91_RS06350 ENOG4105DMQ Methyltransferase FOC91_RS06355 ENOG4105E0A ABC, transporter FOC91_RS06360 ENOG4108IHU transport system permease protein FOC91_RS06365 ENOG4105DQ5 transport system permease protein FOC91_RS06370 ENOG4108MES Periplasmic binding protein FOC91_RS06375 ENOG4105DUX Transporter FOC91_RS06390 ENOG4105DAA L-lactate FOC91_RS06395 ENOG4108IJ0 Aspartate ammonia-lyase FOC91_RS06400 ENOG4105C37 (CBS) domain FOC91_RS06405 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC91_RS06410 ENOG4105D9N nucleoside FOC91_RS06415 ENOG4108KGH TRANSCRIPTIONal FOC91_RS06420 ENOG41073R8 VanW family FOC91_RS06455 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC91_RS06460 ENOG4105C59 p-type ATPase FOC91_RS06470 ENOG4105CUB amino acid FOC91_RS06490 ENOG4108JB9 formate dehydrogenase FOC91_RS06495 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC91_RS06500 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC91_RS06505 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS06510 ENOG4105BZU Histidine kinase FOC91_RS06520 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS06525 ENOG4108UZ3 Transporter FOC91_RS06535 ENOG4105C6K Malic enzyme FOC91_RS06545 ENOG4108MRH transcriptional regulatory protein FOC91_RS06570 ENOG4105US7 Histidine kinase FOC91_RS06575 ENOG4108STX response regulator FOC91_RS06580 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOC91_RS06585 ENOG4105BZ7 extracellular solute-binding protein family 1 FOC91_RS06590 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOC91_RS06595 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FOC91_RS06600 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC91_RS06605 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC91_RS06625 ENOG4105D4T Citrate transporter FOC91_RS06630 ENOG4108V9W transcriptional regulatory protein FOC91_RS06635 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC91_RS06645 ENOG4105DZ6 Band 7 protein FOC91_RS06660 ENOG4105C94 Transporter FOC91_RS06680 ENOG4105CYN Serine protein kinase FOC91_RS06690 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC91_RS06700 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC91_RS06710 ENOG4107ZQN disulfide bond FOC91_RS06715 ENOG4108JQC penicillin-binding protein 1A FOC91_RS06745 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC91_RS06880 ENOG4105G5W regulator Fur family FOC91_RS06885 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC91_RS06905 ENOG4108IUW ABC transporter FOC91_RS06915 ENOG4105CBC glutamate synthase FOC91_RS06920 ENOG4107NBY Membrane FOC91_RS06925 ENOG4105BZ1 (ABC) transporter FOC91_RS06945 ENOG4106BXE FOC91_RS06950 ENOG4105CEN a g-specific adenine glycosylase FOC91_RS06955 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC91_RS06985 ENOG4105ECP epimerase FOC91_RS06990 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC91_RS07010 ENOG4105F1A Pyruvate formate-lyase FOC91_RS07030 ENOG4105C3I Nad-dependent epimerase dehydratase FOC91_RS07035 ENOG4107QQG Dehydrogenase FOC91_RS07040 ENOG4105CKK Glycosyl transferase, family 2 FOC91_RS07055 ENOG4108A04 Beta-lactamase FOC91_RS07150 ENOG4105UPD Calcium Proton FOC91_RS07155 ENOG410606W general stress protein FOC91_RS07170 ENOG4107ZTW SNARE associated Golgi FOC91_RS07190 ENOG4108IPJ Membrane FOC91_RS07195 ENOG4105C59 p-type ATPase FOC91_RS07200 ENOG4107U9T Pfam:Ribonuclease_BN FOC91_RS07210 ENOG4105KJF protein tyrosine phosphatase FOC91_RS07230 ENOG4108TTB tellurium resistance protein FOC91_RS07235 ENOG4107TS3 membrane protein, TerC FOC91_RS07240 ENOG4106FN3 tellurium resistance protein FOC91_RS07245 ENOG4106FN3 tellurium resistance protein FOC91_RS07250 ENOG4108N0M stress protein FOC91_RS07280 ENOG4105DEU major facilitator superfamily FOC91_RS07300 ENOG41062JF Transcriptional regulator FOC91_RS07330 ENOG4105C5H ABC transporter FOC91_RS07350 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC91_RS07365 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC91_RS07395 ENOG4105CI1 PTS System FOC91_RS07405 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC91_RS07410 ENOG4105C8Q Methyl-accepting chemotaxis FOC91_RS07420 ENOG4105EAB amino acid AbC transporter FOC91_RS07425 ENOG4105E5Q amino acid AbC transporter FOC91_RS07430 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase FOC91_RS07440 ENOG4107QJZ Glycosyl transferase, family 2 FOC91_RS07455 ENOG4105D2S major facilitator superfamily FOC91_RS07460 ENOG410756H nucleotidyltransferase FOC91_RS07480 ENOG4105BZU Histidine kinase FOC91_RS07500 ENOG4106UIA FOC91_RS07505 ENOG4106UIA FOC91_RS07525 ENOG4108V5C ABC transporter FOC91_RS07530 ENOG4105DQ5 transport system permease protein FOC91_RS07535 ENOG4105EHG Permease protein FOC91_RS07560 ENOG4105D3R alkyl hydroperoxide reductase FOC91_RS07580 ENOG4105DFD Na H antiporter FOC91_RS07590 ENOG4105DTQ mandelate racemase muconate lactonizing FOC91_RS07605 ENOG4108W15 Protein of unknown function (DUF1456) FOC91_RS07610 ENOG4105BZU Histidine kinase FOC91_RS07620 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC91_RS07625 ENOG4105D9N nucleoside FOC91_RS07645 ENOG4105KPY Small multidrug resistance protein FOC91_RS07650 ENOG4105C26 Dehydrogenase FOC91_RS07660 ENOG4108JPW Aminotransferase FOC91_RS07665 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC91_RS07670 ENOG4105CBD Diacylglycerol kinase FOC91_RS07690 ENOG4107I77 yiaA/B two helix domain FOC91_RS07695 ENOG410834F Transcriptional regulator FOC91_RS07715 ENOG4105D01 (LipO)protein FOC91_RS07720 ENOG4108UMI ABC transporter, permease FOC91_RS07725 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC91_RS07730 ENOG4108W2Y isochorismatase FOC91_RS07760 ENOG4105C4R Atp-dependent dna helicase FOC91_RS07785 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC91_RS07795 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC91_RS07820 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC91_RS07830 ENOG4105C83 adenylosuccinate lyase FOC91_RS07835 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC91_RS07840 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC91_RS07865 ENOG4105SX7 Transporter FOC91_RS07885 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS07960 ENOG4107ZXU DSBA oxidoreductase FOC91_RS07985 ENOG4105BZU Histidine kinase FOC91_RS07995 ENOG4105C7N Xanthine uracil vitamin C permease FOC91_RS08010 ENOG4107EV6 Inherit from COG: YD repeat protein FOC91_RS08025 ENOG4108TYN CAAX amino terminal protease family protein FOC91_RS08040 ENOG4105C5H ABC transporter FOC91_RS08050 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC91_RS08055 ENOG41072GX Peptidase M22 Glycoprotease FOC91_RS08060 ENOG4105K8N protein family UPF0079, ATPase FOC91_RS08160 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC91_RS08170 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC91_RS08175 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC91_RS08185 ENOG4107ZXI Rhomboid family FOC91_RS08200 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC91_RS08205 ENOG4105CPF Cell wall formation (By similarity) FOC91_RS08210 ENOG4108SC4 )-transporter FOC91_RS08220 ENOG4105ERH Fumarylacetoacetate hydrolase FOC91_RS08225 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC91_RS08255 ENOG410667J hydrolase FOC91_RS08260 ENOG4108JQ7 (ABC) transporter FOC91_RS08265 ENOG4105C3U ABC transporter FOC91_RS08270 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC91_RS08280 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FOC91_RS08295 ENOG4105C5H ABC transporter FOC91_RS08320 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC91_RS08330 ENOG4108RE7 deoxyribonuclease FOC91_RS08340 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC91_RS08360 ENOG4105F6E Acyl-transferase FOC91_RS08390 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC91_RS08395 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC91_RS08400 ENOG4105E0C molybdate abc transporter FOC91_RS08410 ENOG4107XDY Nicotinamide Mononucleotide Transporter FOC91_RS08415 ENOG4105II7 pyrroline-5-carboxylate reductase FOC91_RS08425 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC91_RS08430 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC91_RS08460 ENOG4108JQ7 (ABC) transporter FOC91_RS08465 ENOG4105C3U ABC transporter FOC91_RS08470 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC91_RS08475 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC91_RS08490 ENOG4105C2C drug resistance transporter, Bcr CflA FOC91_RS08505 ENOG4105IQ5 FAD linked oxidase domain protein FOC91_RS08520 ENOG4105D01 (LipO)protein FOC91_RS08525 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC91_RS08530 ENOG4108UMI ABC transporter, permease FOC91_RS08570 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) FOC91_RS08580 ENOG4105CMG Carbohydrate kinase FOC91_RS08615 ENOG4107U5W ybbr family FOC91_RS08620 ENOG4105C8B TIGR00159 family FOC91_RS08700 ENOG4108NMV polysaccharide deacetylase FOC91_RS08715 ENOG4105D1F ATP-binding protein FOC91_RS08745 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC91_RS08790 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC91_RS08800 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC91_RS08930 ENOG4105XPM ribosomal protein FOC91_RS08945 ENOG4107Y49 methyltransferase FOC91_RS08970 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC91_RS08985 ENOG4105QIV RNA polymerase FOC91_RS08990 ENOG4105M0M Tetracycline resistance protein FOC91_RS08995 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC91_RS09010 ENOG4105D7W serine acetyltransferase FOC91_RS09030 ENOG4105CTP PilT protein domain protein FOC91_RS09040 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC91_RS09055 ENOG4108Z0C Uvrb UvrC protein FOC91_RS09145 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC91_RS09155 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC91_RS09160 ENOG4105KRF dihydroneopterin aldolase FOC91_RS09165 ENOG4105EEI dihydropteroate synthase FOC91_RS09170 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC91_RS09175 ENOG4105DDQ anthranilate synthase FOC91_RS09180 ENOG4105CRQ synthase (Component I) FOC91_RS09185 ENOG4105C6T cysteine synthase FOC91_RS09200 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC91_RS09205 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC91_RS09230 ENOG41060GV RNA binding s1 domain protein FOC91_RS09245 ENOG4105VYY sporulation protein yabp FOC91_RS09250 ENOG41082I2 s4 domain protein FOC91_RS09255 ENOG4108IY2 MazG family FOC91_RS09265 ENOG4108M14 stage v sporulation protein t FOC91_RS09270 ENOG4108JA2 transcriptioN-repair coupling factor FOC91_RS09300 ENOG4105KME endoribonuclease L-psp FOC91_RS09305 ENOG4105DFT pur operon repressor FOC91_RS09320 ENOG4105W42 Veg protein FOC91_RS09325 ENOG4105XFA sporulation peptidase YabG FOC91_RS09335 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC91_RS09340 ENOG4105F8V Hydrolase, tatD family FOC91_RS09350 ENOG4105KRN Transcriptional regulator, abrb family FOC91_RS09355 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC91_RS09365 ENOG41060K3 Methyltransferase FOC91_RS09375 ENOG4105MA4 psp1 domain protein FOC91_RS09380 ENOG4105FA2 dna polymerase iii FOC91_RS09390 ENOG4105CXN decarboxylase FOC91_RS09425 ENOG41067KS pro-sigma K processing FOC91_RS09445 ENOG4105C6E dna polymerase iii FOC91_RS09455 ENOG4108Z6B deaminase FOC91_RS09460 ENOG4105GTG Isochorismatase FOC91_RS09470 ENOG4105ZMH deoxynucleoside kinase FOC91_RS09505 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC91_RS09540 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC91_RS09555 ENOG410848D S4 domain protein YaaA FOC91_RS09560 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC91_RS09580 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC91_RS09610 ENOG4107QJE Chromosome Partitioning Protein FOC91_RS09615 ENOG4105FA0 parb-like partition protein FOC91_RS09620 ENOG4108ZDA Sporulation protein YyaC FOC91_RS09625 ENOG4105D8X mechanosensitive ion channel FOC91_RS09630 ENOG4105VDK protein, conserved in bacteria FOC91_RS09635 ENOG4105C3G gtp-binding protein FOC91_RS09645 ENOG4108UUM single-stranded DNA-binding protein FOC91_RS09655 ENOG4108XMW Membrane FOC91_RS09660 ENOG4105BZR domain protein FOC91_RS09670 ENOG4105CDU Replicative dna helicase FOC91_RS09700 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS09705 ENOG4105BZU Histidine kinase FOC91_RS09720 ENOG4105Q2H domain protein FOC91_RS09725 ENOG4105C0H protease FOC91_RS09745 ENOG4105DPN Oligoendopeptidase f FOC91_RS09760 ENOG4105C1J atp-dependent rna helicase FOC91_RS09770 ENOG4108UT2 hemolysin iii FOC91_RS09775 ENOG4105CMR udp-glucose 4-epimerase FOC91_RS09785 ENOG4105IW1 AmiS UreI transporter FOC91_RS09795 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC91_RS09810 ENOG4107RGD Major Facilitator superfamily FOC91_RS09815 ENOG4108HRK Histidine kinase FOC91_RS09820 ENOG4105DY9 regulatoR FOC91_RS09835 ENOG4106F5Q Membrane FOC91_RS09840 ENOG4105E0X reductase FOC91_RS09850 ENOG41067SE Tetr family transcriptional regulator FOC91_RS09855 ENOG4105CKK Glycosyl transferase, family 2 FOC91_RS09875 ENOG4105C5H ABC transporter FOC91_RS09880 ENOG4105JEU Glycosyl transferase, family 2 FOC91_RS09890 ENOG4108S4H thioesterase Superfamily protein FOC91_RS09900 ENOG4106YBV Methyl-accepting chemotaxis FOC91_RS09905 ENOG4105EN6 Membrane FOC91_RS09925 ENOG41079KZ Major Facilitator Superfamily FOC91_RS09930 ENOG4105DY9 regulatoR FOC91_RS09935 ENOG4105D22 carbon starvation protein FOC91_RS09940 ENOG4105VCD cytoplasmic protein FOC91_RS09945 ENOG4105BZU Histidine kinase FOC91_RS09950 ENOG4105DWF phosphomethylpyrimidine kinase FOC91_RS09955 ENOG4105BZU Histidine kinase FOC91_RS09960 ENOG4105WH1 Two component transcriptional regulator luxr family FOC91_RS09970 ENOG4108Y4K DNA-binding transcriptional activator FOC91_RS09975 ENOG4105D7V transposase FOC91_RS10000 ENOG4105D6E homoserine dehydrogenase FOC91_RS10015 ENOG41090WU lipolytic protein G-D-S-L family FOC91_RS10020 ENOG4105CJ1 ABC, transporter FOC91_RS10025 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC91_RS10035 ENOG4105VCH membrane FOC91_RS10040 ENOG410667J hydrolase FOC91_RS10050 ENOG4107SVH Potassium channel protein FOC91_RS10070 ENOG4108VKI Cell wall hydrolase FOC91_RS10085 ENOG4108IJ2 phosphate acetyltransferase FOC91_RS10100 ENOG4108VCI transcription factor, rsfa family FOC91_RS10110 ENOG4105DQ5 transport system permease protein FOC91_RS10115 ENOG4105EHG Permease protein FOC91_RS10120 ENOG4105E0A ABC, transporter FOC91_RS10125 ENOG4108MES Periplasmic binding protein FOC91_RS10130 ENOG4105DCI Phosphohydrolase FOC91_RS10135 ENOG41069HH 4-oxalocrotonate tautomerase FOC91_RS10140 ENOG4108Z4T Peptidase M50 FOC91_RS10145 ENOG4108XFG YwhD family FOC91_RS10150 ENOG4105BZ4 penicillin-binding protein FOC91_RS10155 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC91_RS10160 ENOG4107SWG transcriptional regulator MERR family FOC91_RS10165 ENOG4105DXB Major Facilitator superfamily FOC91_RS10175 ENOG4105CYW agmatinase FOC91_RS10195 ENOG410684U Domain of unknown function (DUF1934) FOC91_RS10205 ENOG4105EMN RNA polymerase sigma factor FOC91_RS10225 ENOG4105IIU Aminopeptidase FOC91_RS10235 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC91_RS10240 ENOG4108M15 ABC transporter FOC91_RS10245 ENOG4105KCT ABC transporter FOC91_RS10250 ENOG4105BZU Histidine kinase FOC91_RS10275 ENOG4105BZU Histidine kinase FOC91_RS10290 ENOG4105DF6 Fe-S oxidoreductase FOC91_RS10300 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC91_RS10305 ENOG4105C1G acyl-Coa dehydrogenase FOC91_RS10310 ENOG4105C1G acyl-Coa dehydrogenase FOC91_RS10350 ENOG4105CBT Fructose-1,6-bisphosphatase FOC91_RS10355 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC91_RS10375 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC91_RS10380 ENOG4108ZXQ stage ii sporulation protein r FOC91_RS10390 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC91_RS10410 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC91_RS10415 ENOG4108VGI doxx family FOC91_RS10430 ENOG4108YZG isomerase FOC91_RS10460 ENOG41062M3 atp synthase FOC91_RS10465 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC91_RS10515 ENOG4105BZU Histidine kinase FOC91_RS10530 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC91_RS10535 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC91_RS10560 ENOG4105D65 subunit l FOC91_RS10565 ENOG4105C8S subunit m FOC91_RS10570 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC91_RS10575 ENOG4106778 Protein of unknown function (DUF1146) FOC91_RS10595 ENOG4105DY9 regulatoR FOC91_RS10610 ENOG4105FRN stage II sporulation protein FOC91_RS10620 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC91_RS10635 ENOG4107YJ4 chain length determinant protein FOC91_RS10640 ENOG4105HTX biosynthesis protein FOC91_RS10645 ENOG4107YJ4 chain length determinant protein FOC91_RS10650 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FOC91_RS10655 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC91_RS10665 ENOG4105C30 Nad-dependent epimerase dehydratase FOC91_RS10670 ENOG4105C0K Gdp-mannose 4,6-dehydratase FOC91_RS10690 ENOG4105CPK Glycosyl transferase (Group 1 FOC91_RS10695 ENOG4107XB0 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase FOC91_RS10700 ENOG4108UHC Glycosyl transferase, wecb taga cpsf family FOC91_RS10705 ENOG4105CJT Mannose-1-phosphate guanylyltransferase FOC91_RS10715 ENOG4105DG6 mannose-6-phosphate isomerase FOC91_RS10720 ENOG4108KGH TRANSCRIPTIONal FOC91_RS10730 ENOG4105CMR udp-glucose 4-epimerase FOC91_RS10740 ENOG4105DM4 PTS System FOC91_RS10745 ENOG4105DG6 mannose-6-phosphate isomerase FOC91_RS10750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS10770 ENOG4105CXY transporter FOC91_RS10790 ENOG4105C19 ABC transporter FOC91_RS10795 ENOG4107RBB ABC transporter, permease FOC91_RS10810 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS10840 ENOG4105C0D helicase FOC91_RS10845 ENOG4105KBK Zinc finger, swim domain protein FOC91_RS10870 ENOG41069ER domain protein FOC91_RS10875 ENOG4105C94 Transporter FOC91_RS10880 ENOG4107R8N Glycosyl transferase, family 2 FOC91_RS10905 ENOG4105E0M Sulfatase FOC91_RS10915 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC91_RS10925 ENOG4105D7V transposase FOC91_RS10930 ENOG4105DAA L-lactate FOC91_RS10965 ENOG4107RSM transcriptional regulator FOC91_RS10970 ENOG4105ECB domain protein FOC91_RS10990 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC91_RS11005 ENOG4105VZJ PTS System FOC91_RS11015 ENOG4105VCP PTS System FOC91_RS11035 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) FOC91_RS11045 ENOG4105CK1 PTS System FOC91_RS11050 ENOG4105VCP PTS System FOC91_RS11055 ENOG4105F8D glycoside hydrolase family 4 FOC91_RS11075 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC91_RS11085 ENOG4105ESV Glycosyl transferase, family 4 FOC91_RS11090 ENOG4105C6Y Udp-glucose 6-dehydrogenase FOC91_RS11095 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC91_RS11100 ENOG4108KGH TRANSCRIPTIONal FOC91_RS11105 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC91_RS11115 ENOG4105KVH Transcriptional regulator FOC91_RS11130 ENOG41081UC Inherit from COG: Competence protein FOC91_RS11135 ENOG4105VEQ Cold shock protein FOC91_RS11140 ENOG4105MS2 ribosomal subunit Interface protein FOC91_RS11160 ENOG4105CAK Cell division ATP-binding protein ftsE FOC91_RS11165 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC91_RS11170 ENOG4105CN1 protease FOC91_RS11180 ENOG4105BZ1 (ABC) transporter FOC91_RS11190 ENOG4105C5H ABC transporter FOC91_RS11195 ENOG4108WS4 fmn reductase FOC91_RS11205 ENOG4105DUM transcriptional regulator, lysR family FOC91_RS11210 ENOG4105HMI Membrane FOC91_RS11235 ENOG4107TXC Transcriptional regulator FOC91_RS11250 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC91_RS11255 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC91_RS11265 ENOG41086DT Membrane protein of unknown function FOC91_RS11285 ENOG4108S4C acetyltransferase FOC91_RS11295 ENOG4105C3M thioredoxin reductase FOC91_RS11305 ENOG4108Z4K mutator MutT protein FOC91_RS11315 ENOG4105CHW UPF0052 protein FOC91_RS11325 ENOG4105KRI phosphocarrier protein (HPr FOC91_RS11335 ENOG4105H67 Protein of unknown function (DUF421) FOC91_RS11350 ENOG4105CZ3 stage V sporulation protein ad FOC91_RS11355 ENOG41090VF Stage v sporulation protein ac FOC91_RS11375 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS11425 ENOG41067MG lrgb family FOC91_RS11430 ENOG4105XZU Preprotein translocase, subunit SecG FOC91_RS11440 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC91_RS11455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS11470 ENOG4105CM4 permease protein FOC91_RS11475 ENOG4108IPW abc transporter atp-binding protein FOC91_RS11495 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC91_RS11500 ENOG4105C5H ABC transporter FOC91_RS11525 ENOG4105WMR Protein CrcB homolog FOC91_RS11535 ENOG4105C8Q Methyl-accepting chemotaxis FOC91_RS11550 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FOC91_RS11565 ENOG4105KVH Transcriptional regulator FOC91_RS11570 ENOG4105F27 Major Facilitator FOC91_RS11575 ENOG4105CV8 reductase FOC91_RS11590 ENOG4108RYK Nad-dependent epimerase dehydratase FOC91_RS11605 ENOG4105D9N nucleoside FOC91_RS11610 ENOG4105D9N nucleoside FOC91_RS11630 ENOG4108URH decarboxylase FOC91_RS11645 ENOG4108RMU ferritin dps family protein FOC91_RS11655 ENOG4105NCW Trka-c domain protein FOC91_RS11660 ENOG4107S91 Sodium hydrogen exchanger FOC91_RS11680 ENOG4105D4Y metalloprotease FOC91_RS11685 ENOG4105VG1 fes assembly suf system protein FOC91_RS11690 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC91_RS11695 ENOG4105C8Q Methyl-accepting chemotaxis FOC91_RS11715 ENOG4105BZU Histidine kinase FOC91_RS11720 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS11725 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC91_RS11735 ENOG4107ZTW SNARE associated Golgi FOC91_RS11770 ENOG4107AYK membrAne FOC91_RS11780 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC91_RS11795 ENOG4107R7I amino acid FOC91_RS11800 ENOG4108SUT Major Facilitator Superfamily FOC91_RS11820 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC91_RS11840 ENOG4105DZ1 carboxypeptidase FOC91_RS11855 ENOG4105CHU acetyl-coa acetyltransferase FOC91_RS11860 ENOG4105C1G acyl-Coa dehydrogenase FOC91_RS11885 ENOG4108IUW ABC transporter FOC91_RS11895 ENOG4108W8B Beta-lactamase domain protein FOC91_RS11920 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FOC91_RS11965 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC91_RS11995 ENOG4108UMI ABC transporter, permease FOC91_RS12000 ENOG4105D01 (LipO)protein FOC91_RS12005 ENOG4105D01 (LipO)protein FOC91_RS12010 ENOG4105C3K feS assembly ATPase SufC FOC91_RS12015 ENOG4105JRK feS assembly protein SufD FOC91_RS12020 ENOG4105C9B Cysteine desulfurase FOC91_RS12025 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC91_RS12030 ENOG4105DIW FeS assembly protein SUFB FOC91_RS12045 ENOG4107R8B 5'-nucleotidase FOC91_RS12050 ENOG4105KZD Domain of unknown function (DUF1805) FOC91_RS12060 ENOG4105FAA peptidase M23 FOC91_RS12085 ENOG41090T1 Membrane FOC91_RS12090 ENOG4107TXC Transcriptional regulator FOC91_RS12095 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC91_RS12100 ENOG4105MMD transcriptional regulator FOC91_RS12115 ENOG4105CBT Fructose-1,6-bisphosphatase FOC91_RS12130 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC91_RS12135 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC91_RS12140 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC91_RS12155 ENOG4108W5N phosphatidylglycerophosphatase a FOC91_RS12170 ENOG41083MR nifu domain-containing protein FOC91_RS12195 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC91_RS12200 ENOG4105C4B ABC transporter, permease FOC91_RS12205 ENOG4108JJA ABC, transporter FOC91_RS12230 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC91_RS12245 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) FOC91_RS12470 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC91_RS12495 ENOG4105EWC Purine nucleoside phosphorylase FOC91_RS12525 ENOG4105CEP NADH dehydrogenase FOC91_RS12540 ENOG41069ER domain protein FOC91_RS12560 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC91_RS12575 ENOG4105KA0 thioesterase Superfamily protein FOC91_RS12595 ENOG4107R3E Citrate transporter FOC91_RS12605 ENOG4105Y38 Kinase-associated protein B FOC91_RS12620 ENOG4105C87 Aminotransferase class I and II FOC91_RS12630 ENOG4108MUZ hydrolase FOC91_RS12635 ENOG4105C5I Dehydrogenase FOC91_RS12640 ENOG4108ZB6 transcriptional regulator AsnC family FOC91_RS12645 ENOG4105CHM Aminotransferase FOC91_RS12655 ENOG4105WG9 Conserved Protein FOC91_RS12670 ENOG4107PBV potassium channel FOC91_RS12675 ENOG4105KT7 mgtC SapB transporter FOC91_RS12710 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC91_RS12810 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC91_RS12855 ENOG4105VEQ Cold shock protein FOC91_RS12865 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC91_RS12870 ENOG4105E4F Isochorismate synthase FOC91_RS12880 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC91_RS12885 ENOG4108IPT Naphthoate synthase FOC91_RS12895 ENOG4105DTQ mandelate racemase muconate lactonizing FOC91_RS12915 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC91_RS12940 ENOG4105C6Z Gluconate FOC91_RS12980 ENOG41086D8 Transcriptional regulator FOC91_RS12985 ENOG4105C19 ABC transporter FOC91_RS13000 ENOG4107ZTW SNARE associated Golgi FOC91_RS13020 ENOG4105D7V transposase FOC91_RS13030 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC91_RS13035 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC91_RS13060 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS13065 ENOG4105BZU Histidine kinase FOC91_RS13070 ENOG4105N67 Proton-coupled thiamine transporter YuaJ FOC91_RS13135 ENOG41087YS Phage shock protein A FOC91_RS13180 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC91_RS13185 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC91_RS13190 ENOG4108V2W Carbonate dehydratase FOC91_RS13245 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC91_RS13255 ENOG4105D2X ABC transporter substrate-binding protein FOC91_RS13270 ENOG4107T7U Sulfatase FOC91_RS13275 ENOG4107S9D Alpha beta hydrolase FOC91_RS13280 ENOG4105BZU Histidine kinase FOC91_RS13285 ENOG4105BZU Histidine kinase FOC91_RS13295 ENOG4105E98 transcriptional regulator DeoR family FOC91_RS13300 ENOG4107XGZ Hydrolase FOC91_RS13365 ENOG4108RIR Molybdenum cofactor biosynthesis protein FOC91_RS13375 ENOG4105BZF Glycosyl transferase (Group 1 FOC91_RS13380 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC91_RS13385 ENOG4108Z0R Transferase FOC91_RS13390 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC91_RS13435 ENOG4105CIG ABC transporter FOC91_RS13445 ENOG4105N5T Radical SAM Protein FOC91_RS13465 ENOG4105C19 ABC transporter FOC91_RS13480 ENOG4105NCW Trka-c domain protein FOC91_RS13485 ENOG4107S91 Sodium hydrogen exchanger FOC91_RS13490 ENOG410605W Major Facilitator FOC91_RS13525 ENOG4108B31 Spore germination protein FOC91_RS13535 ENOG4105DWV Homoserine O-trans-acetylase FOC91_RS13545 ENOG41085GJ domain protein FOC91_RS13565 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC91_RS13570 ENOG4105D06 uba thif-type nad fad binding protein FOC91_RS13580 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC91_RS13585 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC91_RS13590 ENOG4108ZAF Molybdopterin FOC91_RS13610 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC91_RS13615 ENOG4108VJ1 Transcriptional regulator (CarD family FOC91_RS13650 ENOG4105CBX hi0933 family FOC91_RS13665 ENOG4105YW5 deoR family transcriptional regulator FOC91_RS13670 ENOG4107QSE Dipeptidase FOC91_RS13680 ENOG4108IUM Glycogen debranching enzyme FOC91_RS13685 ENOG4108V15 phosphotransferase enzyme family FOC91_RS13700 ENOG4105C8F Beta-lactamase domain protein FOC91_RS13730 ENOG4108VDD TRNA binding domain protein FOC91_RS13760 ENOG4105K7K Transcriptional regulator FOC91_RS13805 ENOG4105C88 aminopeptidase FOC91_RS13825 ENOG4105ETE Transcriptional regulator (LacI family FOC91_RS13855 ENOG4105EP9 oxidoreductase FOC91_RS13860 ENOG4107SNB ankyrin repeat protein YahD FOC91_RS13865 ENOG4105BZU Histidine kinase FOC91_RS13870 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS13885 ENOG4105DGU Histone deacetylase FOC91_RS13890 ENOG4105W87 Cbs domain FOC91_RS13895 ENOG4105F1V Acetoin utilization protein FOC91_RS13910 ENOG4105EMN RNA polymerase sigma factor FOC91_RS13940 ENOG4105C28 cystathionine FOC91_RS13950 ENOG4105U5Y Transcriptional regulator FOC91_RS13960 ENOG4106KR7 LysR family Transcriptional regulator FOC91_RS13985 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC91_RS13995 ENOG4105EFZ amidohydrolase FOC91_RS14010 ENOG4105KBJ sporulation protein ytfj FOC91_RS14015 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC91_RS14025 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FOC91_RS14045 ENOG4108JYZ YitT family FOC91_RS14085 ENOG4107YZX Universal stress protein FOC91_RS14105 ENOG4105VZ8 Transcriptional regulator FOC91_RS14115 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC91_RS14160 ENOG4105DC7 peptidase M24 FOC91_RS14195 ENOG4105SFS phosphoesterase RecJ domain protein FOC91_RS14205 ENOG4105VV2 FOC91_RS14210 ENOG4105C0B DNA polymerase III (alpha subunit) FOC91_RS14215 ENOG4105C6K Malic enzyme FOC91_RS14220 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS14245 ENOG4105FS0 cytoplasmic membrane protein FOC91_RS14250 ENOG4108REF Sporulation integral membrane protein ytvi FOC91_RS14260 ENOG4105BZN citrate synthase FOC91_RS14265 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC91_RS14285 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS14290 ENOG4105BZU Histidine kinase FOC91_RS14295 ENOG4105C2M dna polymerase I FOC91_RS14310 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FOC91_RS14315 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC91_RS14340 ENOG4108TDW sporulation protein YtxC FOC91_RS14345 ENOG4105C22 threonyL-tRNA synthetase FOC91_RS14370 ENOG4105CN9 Peptidase m42 family protein FOC91_RS14375 ENOG4108JGH Tetr family transcriptional regulator FOC91_RS14380 ENOG4105CW7 secretion protein, HlyD family FOC91_RS14385 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC91_RS14430 ENOG4108RWN rrna methyltransferase FOC91_RS14480 ENOG4105DCG PHP domain protein FOC91_RS14490 ENOG4105FE9 pseudouridine synthase FOC91_RS14500 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC91_RS14505 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC91_RS14520 ENOG4105E0A ABC, transporter FOC91_RS14525 ENOG4105KFN sortase, SrtB family FOC91_RS14540 ENOG4105DR4 Methyltransferase FOC91_RS14555 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS14595 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC91_RS14600 ENOG4105J76 Periplasmic binding protein FOC91_RS14610 ENOG4105CEY Amp-dependent synthetase and ligase FOC91_RS14615 ENOG4107Z3H Transcriptional regulator, TetR family FOC91_RS14620 ENOG41060WC Enoyl-CoA hydratase FOC91_RS14625 ENOG4105BZJ Electron transfer flavoprotein FOC91_RS14630 ENOG4105C10 Electron transfer flavoprotein FOC91_RS14635 ENOG4105K63 Thioredoxin FOC91_RS14650 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC91_RS14660 ENOG4105E33 succinate dehydrogenase FOC91_RS14670 ENOG4108VXD carboxy-peptidase FOC91_RS14675 ENOG4105E14 MotA TolQ exbB proton channel FOC91_RS14680 ENOG4105ER2 Ompa motb domain protein FOC91_RS14685 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC91_RS14690 ENOG4108IUX (ABC) transporter FOC91_RS14695 ENOG4105RHA ABC transporter, permease FOC91_RS14700 ENOG4108Z40 Transcriptional regulator FOC91_RS14705 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC91_RS14715 ENOG4108JCI Transcriptional regulator FOC91_RS14725 ENOG4105DZC cytosine deaminase FOC91_RS14735 ENOG4105PFC Transcriptional regulator FOC91_RS14750 ENOG4105KBX Transcriptional regulator, TetR family FOC91_RS14760 ENOG4108PCX Major Facilitator FOC91_RS14770 ENOG4108XJQ germination protein FOC91_RS14785 ENOG4105M59 Phosphodiesterase, mj0936 family FOC91_RS14800 ENOG4108QCI YvbH-like oligomerisation region FOC91_RS14830 ENOG4108IUQ atp-dependent protease FOC91_RS14850 ENOG4105K56 Transcriptional regulator FOC91_RS14875 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC91_RS14885 ENOG41068KH stage VI sporulation protein D FOC91_RS14900 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC91_RS14920 ENOG4105DFF Rod shape-determining protein mreb FOC91_RS14940 ENOG4107QMS site-determining protein FOC91_RS14955 ENOG4105C03 ribonuclease FOC91_RS14965 ENOG4105X36 (ribosomal) protein FOC91_RS14990 ENOG4105EWM Histidine kinase FOC91_RS15010 ENOG4105CQC Prephenate dehydratase FOC91_RS15015 ENOG4108RPX mosc domain containing protein FOC91_RS15030 ENOG4108IYU L-aspartate oxidase FOC91_RS15035 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC91_RS15060 ENOG41082BM Transcriptional regulator, arsr family FOC91_RS15065 ENOG4108IPJ Membrane FOC91_RS15075 ENOG4108HUF Transporter FOC91_RS15090 ENOG41061AI Protein of unknown function (DUF2905) FOC91_RS15105 ENOG4105VIE preprotein translocase, subunit YajC FOC91_RS15115 ENOG4108QG2 Membrane FOC91_RS15120 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC91_RS15130 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC91_RS15135 ENOG41076HS cation diffusion facilitator family transporter FOC91_RS15140 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC91_RS15150 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC91_RS15175 ENOG4105CUZ uba thif-type nad fad binding protein FOC91_RS15180 ENOG4108VCI transcription factor, rsfa family FOC91_RS15185 ENOG4105D1H recombination factor protein RarA FOC91_RS15195 ENOG4105C3J Cysteine desulfurase FOC91_RS15210 ENOG4105C7H Helicase, RecD TraA family FOC91_RS15215 ENOG41060CR FOC91_RS15230 ENOG4105C02 permease FOC91_RS15260 ENOG4105HHA aminodeoxychorismate lyase FOC91_RS15270 ENOG4105XYU peptidase (U32 family) FOC91_RS15275 ENOG4105CFP Peptidase U32 FOC91_RS15290 ENOG4107XRG penicillin-binding protein FOC91_RS15320 ENOG4105C28 cystathionine FOC91_RS15325 ENOG4105C0A alcohol dehydrogenase FOC91_RS15335 ENOG4108V5C ABC transporter FOC91_RS15340 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC91_RS15380 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC91_RS15390 ENOG4105MIR Phenylalanine 4-monooxygenase FOC91_RS15395 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC91_RS15430 ENOG4108MUZ hydrolase FOC91_RS15440 ENOG4105G6Z alkaline phosphatase FOC91_RS15455 ENOG4108TVJ Nitroreductase FOC91_RS15475 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS15490 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC91_RS15495 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC91_RS15505 ENOG410812S Rna-binding protein FOC91_RS15515 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC91_RS15525 ENOG4105DXX methyltransferase FOC91_RS15535 ENOG4105KQC Competence protein FOC91_RS15540 ENOG4108UK2 deaminase FOC91_RS15545 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC91_RS15555 ENOG4105TQK DNA polymerase iii, delta' subunit FOC91_RS15580 ENOG4105KVH Transcriptional regulator FOC91_RS15585 ENOG4105CSA Coproporphyrinogen iii oxidase FOC91_RS15615 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC91_RS15620 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC91_RS15630 ENOG4105KTH gatB Yqey FOC91_RS15635 ENOG41068P3 sporulation protein YqfC FOC91_RS15645 ENOG4105C9A Phoh family FOC91_RS15650 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC91_RS15660 ENOG4107YR5 Diacylglycerol kinase FOC91_RS15665 ENOG4105KG3 cytidine deaminase FOC91_RS15670 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC91_RS15695 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC91_RS15700 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS15715 ENOG4105EGD dinuclear metal center protein, YbgI family FOC91_RS15740 ENOG41069ZM Protein of unknown function (DUF2624) FOC91_RS15745 ENOG4108JYZ YitT family FOC91_RS15750 ENOG4105FDK ABC transporter FOC91_RS15760 ENOG4105N80 Ferric uptake regulator, Fur family FOC91_RS15785 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC91_RS15795 ENOG4107RF6 penicillin-binding protein FOC91_RS15800 ENOG4105PWN phosphate abc transporter FOC91_RS15805 ENOG4105C8U phosphate abc transporter FOC91_RS15810 ENOG4105E2Z phosphate ABC transporter (Permease FOC91_RS15820 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC91_RS15835 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC91_RS15845 ENOG4105DKQ ROK family FOC91_RS15855 ENOG4105C5X domain protein FOC91_RS15875 ENOG4105C28 cystathionine FOC91_RS15880 ENOG4105C28 cystathionine FOC91_RS15890 ENOG4105C3R Methionine synthase FOC91_RS16010 ENOG4105C0D helicase FOC91_RS16040 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS16045 ENOG4105CJ1 ABC, transporter FOC91_RS16080 ENOG41080TC multidrug resistance protein FOC91_RS16100 ENOG4105WZW rhodanese family FOC91_RS16105 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) FOC91_RS16120 ENOG4105K7K Transcriptional regulator FOC91_RS16135 ENOG4107YBY Hydrolase FOC91_RS16145 ENOG4105CBJ Metal-dependent enzyme FOC91_RS16160 ENOG4105DC7 peptidase M24 FOC91_RS16185 ENOG4105CD2 stage iii sporulation protein aa FOC91_RS16190 ENOG4105KR5 Stage iii sporulation protein FOC91_RS16195 ENOG4108CQH stage III sporulation protein AC FOC91_RS16200 ENOG4105KQ4 Stage iii sporulation protein ad FOC91_RS16210 ENOG410644B Stage III sporulation protein af FOC91_RS16235 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC91_RS16240 ENOG4108ZSR alkaline shock protein FOC91_RS16265 ENOG4105CTB Polyprenyl synthetase FOC91_RS16275 ENOG4105DX0 Hemolysin A FOC91_RS16285 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC91_RS16290 ENOG4105S1Z Stage IV sporulation protein B FOC91_RS16295 ENOG4107QQR Sporulation FOC91_RS16310 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC91_RS16320 ENOG4108JUB Transcriptional regulator FOC91_RS16330 ENOG4107RDP Dehydrogenase FOC91_RS16350 ENOG4105CPP Dehydrogenase, E1 component FOC91_RS16355 ENOG4105C7S Dehydrogenase FOC91_RS16365 ENOG4105E09 nadh pyrophosphatase FOC91_RS16370 ENOG4105G7B Protein of unknown function (DUF2992) FOC91_RS16380 ENOG4108HW3 (ABC) transporter FOC91_RS16385 ENOG4105E5Q amino acid AbC transporter FOC91_RS16390 ENOG4105CDA abc transporter atp-binding protein FOC91_RS16395 ENOG4108QEG Membrane FOC91_RS16400 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC91_RS16415 ENOG4105D9U N-acetyltransferase FOC91_RS16420 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC91_RS16430 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC91_RS16455 ENOG4105EJQ L-serine dehydratase FOC91_RS16460 ENOG4105II7 pyrroline-5-carboxylate reductase FOC91_RS16465 ENOG41069FQ Metallo-beta-lactamase superfamily FOC91_RS16470 ENOG4108IXY short-chain dehydrogenase reductase FOC91_RS16485 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FOC91_RS16525 ENOG4105CGH 5'-nucleotidase FOC91_RS16530 ENOG4105DFD Na H antiporter FOC91_RS16540 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC91_RS16555 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC91_RS16560 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC91_RS16585 ENOG4108R6K riboflavin synthase, subunit alpha FOC91_RS16590 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC91_RS16610 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC91_RS16615 ENOG4105ETE Transcriptional regulator (LacI family FOC91_RS16625 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC91_RS16645 ENOG4105RHY Pfam:UPF0157 FOC91_RS16655 ENOG4105CPC Aldo Keto reductase FOC91_RS16675 ENOG4105MZ9 stage II sporulation protein m FOC91_RS16680 ENOG4105I3K Ferric uptake regulator, Fur family FOC91_RS16690 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC91_RS16715 ENOG4105D7N magnesium and cobalt transport protein CorA FOC91_RS16745 ENOG4105DVE abc transporter atp-binding protein FOC91_RS16750 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS16755 ENOG4105DZ1 carboxypeptidase FOC91_RS16760 ENOG41082AN stage II sporulation protein FOC91_RS16770 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS16775 ENOG4105C8J )-transporter FOC91_RS16795 ENOG41090VF Stage v sporulation protein ac FOC91_RS16800 ENOG4105CZ3 stage V sporulation protein ad FOC91_RS16810 ENOG4105G6R Stage v sporulation protein ae FOC91_RS16820 ENOG4105J7I hydrolase FOC91_RS16825 ENOG4105PTM secreted protein FOC91_RS16830 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC91_RS16865 ENOG4105CE4 GlcNAc 6-P deacetylase FOC91_RS16885 ENOG4105CID antiterminator FOC91_RS16900 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC91_RS16920 ENOG4105BZU Histidine kinase FOC91_RS16925 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC91_RS16965 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC91_RS16985 ENOG4105DTD Dehydrogenase FOC91_RS16990 ENOG4105K7K Transcriptional regulator FOC91_RS17020 ENOG4105CHU acetyl-coa acetyltransferase FOC91_RS17070 ENOG4105CG3 alpha amylase, catalytic region FOC91_RS17080 ENOG4107FKK extracellular solute-binding protein family 1 FOC91_RS17090 ENOG4105EG2 ABC transporter, permease FOC91_RS17095 ENOG4105FKQ transcriptional regulator FOC91_RS17100 ENOG4105CHM Aminotransferase FOC91_RS17110 ENOG4108HGU Histidine kinase FOC91_RS17165 ENOG4105UIN FOC91_RS17175 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC91_RS17190 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC91_RS17195 ENOG4105EPM Diguanylate phosphodiesterase FOC91_RS17210 ENOG4107IN1 Protein of unknown function (DUF1797) FOC91_RS17220 ENOG4108XRC Protein of unknown function (DUF458) FOC91_RS17255 ENOG4107ZYR domain protein FOC91_RS17260 ENOG4105CN5 Metallo-Beta-Lactamase FOC91_RS17270 ENOG4108X4Q Hydrolase FOC91_RS17275 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC91_RS17290 ENOG4105CPP Dehydrogenase, E1 component FOC91_RS17340 ENOG4105CXN decarboxylase FOC91_RS17360 ENOG4105ECY inositol monophosphatase FOC91_RS17370 ENOG4105CI3 gtp-binding protein typa FOC91_RS17375 ENOG4105QA2 FOC91_RS17395 ENOG4108IAB Phoh family FOC91_RS17410 ENOG4105CNI cell division protein FtsW FOC91_RS17415 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC91_RS17465 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC91_RS17480 ENOG4107TB6 phosphoglycerate mutase FOC91_RS17500 ENOG4106H78 methyltransferase FOC91_RS17510 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC91_RS17515 ENOG4105D78 K07001 NTE family protein FOC91_RS17520 ENOG41063PX domain protein FOC91_RS17530 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) FOC91_RS17560 ENOG4108IMY Transcriptional regulator FOC91_RS17705 ENOG4105CAR Terminase, large subunit FOC91_RS17715 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) FOC91_RS17790 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC91_RS17800 ENOG41086D8 Transcriptional regulator FOC91_RS17830 ENOG4105KNH Nucleic acid-binding protein FOC91_RS17865 ENOG41068DC Essential cell division protein (By similarity) FOC91_RS17870 ENOG4105CJN penicillin-binding protein FOC91_RS17875 ENOG4105CJN penicillin-binding protein FOC91_RS17880 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC91_RS17895 ENOG4105CNI cell division protein FtsW FOC91_RS17905 ENOG4105D4A Cell wall formation (By similarity) FOC91_RS17910 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) FOC91_RS17915 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC91_RS17920 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC91_RS17930 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC91_RS17940 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC91_RS17945 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC91_RS17950 ENOG4105DFA alanine racemase domain protein FOC91_RS17960 ENOG41067XK integral membrane protein FOC91_RS17965 ENOG4105DBK s4 domain protein FOC91_RS17990 ENOG4105C34 Pseudouridine synthase FOC91_RS18070 ENOG4105DC7 peptidase M24 FOC91_RS18085 ENOG4105DSJ YicC domain protein FOC91_RS18105 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC91_RS18110 ENOG4105C25 Primosomal protein n' FOC91_RS18115 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC91_RS18125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC91_RS18135 ENOG4108ZF3 Phosphatase FOC91_RS18140 ENOG4105D9P serine threonine protein kinase FOC91_RS18145 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC91_RS18150 ENOG4105DJV ribulose-phosphate 3-epimerase FOC91_RS18155 ENOG4105FJ0 thiamine FOC91_RS18170 ENOG4108ZAA Alkaline-shock protein FOC91_RS18175 ENOG4105DP4 dak2 domain fusion protein ylov FOC91_RS18180 ENOG4105CB5 ATP-dependent DNA helicase recG FOC91_RS18195 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC91_RS18200 ENOG4105CHR reductase FOC91_RS18215 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC91_RS18220 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC91_RS18240 ENOG4105VB6 UPF0109 protein FOC91_RS18265 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC91_RS18280 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC91_RS18285 ENOG4105C79 DNA protecting protein DprA FOC91_RS18290 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC91_RS18300 ENOG4108HE4 integrase family FOC91_RS18345 ENOG4105KNE Phosphatidate cytidylyltransferase FOC91_RS18355 ENOG4105DZP Membrane-associated zinc metalloprotease FOC91_RS18370 ENOG4105EKQ RNA-directed DNA polymerase FOC91_RS18375 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC91_RS18385 ENOG4105CHV Transcription elongation factor NusA FOC91_RS18390 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC91_RS18395 ENOG4105VHM ribosomal protein FOC91_RS18405 ENOG4105W7A Protein of unknown function (DUF503) FOC91_RS18420 ENOG4105DTN riboflavin biosynthesis protein ribF FOC91_RS18440 ENOG4105C1V Peptidase, M16 FOC91_RS18450 ENOG4105E35 Dipicolinate synthase subunit A FOC91_RS18455 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC91_RS18460 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC91_RS18470 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC91_RS18480 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC91_RS18490 ENOG4107QZI cell division protein FtsK FOC91_RS18495 ENOG4105FDP GntR family transcriptional regulator FOC91_RS18500 ENOG4105DIH basic membrane FOC91_RS18505 ENOG4108JQ9 ABC transporter FOC91_RS18510 ENOG4105UIB (ABC) transporter FOC91_RS18530 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC91_RS18535 ENOG4105XZV Protein of unknown function (DUF3243) FOC91_RS18550 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC91_RS18575 ENOG4105D48 metallophosphoesterase FOC91_RS18580 ENOG4105MCT stage V sporulation protein S FOC91_RS18585 ENOG4108IGT Dipeptidase FOC91_RS18590 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC91_RS18595 ENOG4105DQU oxidoreductase, subunit beta FOC91_RS18625 ENOG4107QHE Choloylglycine hydrolase FOC91_RS18635 ENOG410890F Dynamin family FOC91_RS18640 ENOG4105E0M Sulfatase FOC91_RS18650 ENOG4105F0V Cell wall hydrolase FOC91_RS18740 ENOG4105BZU Histidine kinase FOC91_RS18745 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC91_RS18775 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC91_RS18780 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC91_RS18790 ENOG4105CGK Exodeoxyribonuclease III FOC91_RS18810 ENOG4105E0A ABC, transporter FOC91_RS18815 ENOG4105NIV Esterase FOC91_RS18835 ENOG4105VPX protein, conserved in bacteria FOC91_RS18840 ENOG410681U heavy metal transport detoxification protein FOC91_RS18845 ENOG4105C59 p-type ATPase FOC91_RS18850 ENOG4105K70 DNA-binding protein FOC91_RS18855 ENOG4105TMB Formate nitrite transporter FOC91_RS18875 ENOG4105C85 amino acid FOC91_RS18885 ENOG4108SJC Membrane FOC91_RS18890 ENOG4107QW4 alcohol dehydrogenase FOC91_RS18895 ENOG4105E98 transcriptional regulator DeoR family FOC91_RS18900 ENOG4105DE4 1-phosphofructokinase FOC91_RS18905 ENOG4105DM4 PTS System FOC91_RS18910 ENOG41069ER domain protein FOC91_RS18940 ENOG4106F1P AAA ATPase, central domain protein FOC91_RS18945 ENOG4105EN6 Membrane FOC91_RS18950 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC91_RS18955 ENOG4105CXI aluminum resistance protein FOC91_RS18960 ENOG4105KV4 Transcriptional regulator FOC91_RS18965 ENOG4105C5F glutamine synthetase FOC91_RS18975 ENOG4105K7K Transcriptional regulator FOC91_RS18995 ENOG4108SVB resolvase FOC91_RS19005 ENOG4105CGH 5'-nucleotidase FOC91_RS19045 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC91_RS19115 ENOG4105T6C Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps FOC91_RS19135 ENOG4105BZ1 (ABC) transporter FOC91_RS19140 ENOG4105BZ1 (ABC) transporter FOC91_RS19155 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC91_RS19180 ENOG41067MG lrgb family FOC91_RS19190 ENOG4107RSM transcriptional regulator FOC91_RS19200 ENOG4105CJ1 ABC, transporter FOC91_RS19220 ENOG4107QIV Cytochrome c biogenesis protein FOC91_RS19235 ENOG4105EKQ RNA-directed DNA polymerase FOC91_RS19275 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) FOC91_RS19300 ENOG4108903 Formimidoylglutamase FOC91_RS19305 ENOG4108VJ1 Transcriptional regulator (CarD family FOC91_RS19310 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC91_RS19315 ENOG4105CBC glutamate synthase FOC91_RS19320 ENOG4105CK7 Sodium proline symporter FOC91_RS19325 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC91_RS19330 ENOG4105FBA Phospholipase Carboxylesterase FOC91_RS19335 ENOG4105BZU Histidine kinase FOC91_RS19345 ENOG4107AYK membrAne FOC91_RS19395 ENOG4108IMY Transcriptional regulator FOC91_RS19405 ENOG4105CEY Amp-dependent synthetase and ligase FOC91_RS19410 ENOG4107ZYJ bioY protein FOC91_RS19415 ENOG4107F3J Amp-dependent synthetase and ligase FOC91_RS19435 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC91_RS19475 ENOG4108I0Z Aconitate hydratase FOC91_RS19480 ENOG4108JJA ABC, transporter FOC91_RS19490 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC91_RS19495 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC91_RS19525 ENOG4105W8X HesB YadR YfhF-family protein FOC91_RS19535 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC91_RS19540 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) FOC91_RS19545 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS19550 ENOG4105C0H protease FOC91_RS19555 ENOG4105K4P CoA-binding domain protein FOC91_RS19560 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC91_RS19570 ENOG4105D9R oxidoreductase FOC91_RS19580 ENOG4105CIG ABC transporter FOC91_RS19600 ENOG4105EMN RNA polymerase sigma factor FOC91_RS19610 ENOG4108KGH TRANSCRIPTIONal FOC91_RS19615 ENOG4107QJT sodium dicarboxylate symporter FOC91_RS19680 ENOG4105E1K spore germination protein FOC91_RS19685 ENOG4108JB9 formate dehydrogenase FOC91_RS19695 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC91_RS19700 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC91_RS19710 ENOG4105TMB Formate nitrite transporter FOC91_RS19715 ENOG4105D06 uba thif-type nad fad binding protein FOC91_RS19720 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC91_RS19725 ENOG4108ZAF Molybdopterin FOC91_RS19735 ENOG4105D1F ATP-binding protein FOC91_RS19750 ENOG410696E Membrane FOC91_RS19755 ENOG4105FR1 rard protein FOC91_RS19765 ENOG4105EWU Squalene--hopene cyclase FOC91_RS19775 ENOG4105CHR reductase FOC91_RS19780 ENOG4105C26 Dehydrogenase FOC91_RS19790 ENOG4108IA2 Sodium pantothenate symporter FOC91_RS19805 ENOG4106IQC argininosuccinate lyase FOC91_RS19815 ENOG410904N short-chain dehydrogenase reductase FOC91_RS19855 ENOG4105VEQ Cold shock protein FOC91_RS19870 ENOG4108R1P FOC91_RS19880 ENOG41073R8 VanW family FOC91_RS19885 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC91_RS19900 ENOG4105KT7 mgtC SapB transporter FOC91_RS19910 ENOG4105E39 Enoyl-CoA hydratase FOC91_RS19915 ENOG4105K64 Glycosyl transferase, family 2 FOC91_RS19925 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC91_RS19950 ENOG4105CQB FAD linked oxidase domain protein FOC91_RS19955 ENOG4105C09 Bile acid FOC91_RS19990 ENOG4105CIS alcohol dehydrogenase FOC91_RS19995 ENOG41082BM Transcriptional regulator, arsr family FOC91_RS20020 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC91_RS20050 ENOG4108A04 Beta-lactamase FOC91_RS20055 ENOG4105DPN Oligoendopeptidase f FOC91_RS20060 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOC91_RS20065 ENOG4105E5K Alpha-amylase FOC91_RS20080 ENOG4105C98 muts2 protein FOC91_RS20100 ENOG4107V2S Transcriptional regulator FOC91_RS20120 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC91_RS20125 ENOG4105NX3 Membrane FOC91_RS20130 ENOG4105DQ5 transport system permease protein FOC91_RS20135 ENOG4105EHG Permease protein FOC91_RS20140 ENOG4108MES Periplasmic binding protein FOC91_RS20155 ENOG4107R3E Citrate transporter FOC91_RS20165 ENOG4108TN2 lmbE family FOC91_RS20195 ENOG4105CIS alcohol dehydrogenase FOC91_RS20235 ENOG4105H3G oxidoreductase FOC91_RS20270 ENOG4107YXZ hydrolase, family 25 FOC91_RS20285 ENOG4105D7V transposase FOC91_RS20290 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC91_RS20365 ENOG4105KVH Transcriptional regulator FOC91_RS20370 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FOC91_RS20390 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC91_RS20425 ENOG4105D9R oxidoreductase FOC91_RS20430 ENOG4108TZY GntR Family Transcriptional Regulator FOC91_RS20465 ENOG4105C44 Serine transporter FOC91_RS20500 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC91_RS20505 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC91_RS20520 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC91_RS20525 ENOG4105C6Z Gluconate FOC91_RS20530 ENOG4105CMG Carbohydrate kinase FOC91_RS20535 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC91_RS20540 ENOG4105XDF Protein of unknown function (DUF1272) FOC91_RS20545 ENOG4105DDN Pentapeptide repeat-containing protein FOC91_RS20560 ENOG4105C37 (CBS) domain FOC91_RS20590 ENOG4105EV4 Multidrug resistance protein mdtH FOC91_RS20600 ENOG4105DMQ Methyltransferase FOC91_RS20640 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC91_RS20650 ENOG4108UW5 maltose o-acetyltransferase FOC91_RS20655 ENOG4105DKQ ROK family FOC91_RS20660 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC91_RS20700 ENOG4105D7V transposase FOC91_RS20750 ENOG4105CJ1 ABC, transporter FOC91_RS20760 ENOG4108PSK reductase FOC91_RS20780 ENOG4105CA9 Pyruvate kinase FOC91_RS20790 ENOG4108RCM Nitroreductase FOC91_RS20795 ENOG4105KVH Transcriptional regulator FOC91_RS20815 ENOG4105WH1 Two component transcriptional regulator luxr family FOC91_RS20825 ENOG4108Z66 YbaK ebsC protein FOC91_RS20830 ENOG4108K8S endonuclease I FOC91_RS20855 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC91_RS20890 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC91_RS20900 ENOG4105CRW Short chain fatty acid transporter FOC91_RS20910 ENOG4107AUC FOC91_RS20915 ENOG4105KBX Transcriptional regulator, TetR family FOC91_RS20920 ENOG4105KPY Small multidrug resistance protein FOC91_RS20925 ENOG4105RXJ FOC91_RS20935 ENOG41069JR FOC91_RS20940 ENOG4105DA5 (ABC) transporter FOC91_RS20955 ENOG4105CZM Major Facilitator FOC91_RS20960 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC91_RS20970 ENOG4108ISG Major Facilitator FOC91_RS21015 ENOG4108IG5 Transcriptional regulator FOC91_RS21025 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC91_RS21040 ENOG4108IBT Inherit from COG: transposase FOC91_RS21055 ENOG410874W AraC family transcriptional regulator FOC91_RS21060 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC91_RS21075 ENOG4108AEY RNA polymerase sigma factor FOC91_RS21095 ENOG4108JQ1 Dehydrogenase FOC91_RS21110 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC91_RS21130 ENOG4106P55 Transcriptional regulator FOC91_RS21140 ENOG4107QR9 Iron-sulfur cluster binding protein FOC91_RS21145 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) FOC91_RS21150 ENOG4105DJB Major Facilitator Superfamily FOC91_RS21155 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC91_RS21165 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 FOC91_RS21170 ENOG4108U05 Transcriptional regulator FOC91_RS21185 ENOG4105BZU Histidine kinase FOC91_RS21200 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC91_RS21220 ENOG4105JQZ Methyltransferase FOC91_RS21225 ENOG4105W1Y Transcriptional regulator FOC91_RS21235 ENOG4105C88 aminopeptidase FOC91_RS21250 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC91_RS21260 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase FOC91_RS21265 ENOG4108NNI Beta-lactamase domain-containing protein FOC91_RS21290 ENOG4105K6H D-cysteine desulfhydrase FOC91_RS21315 ENOG41062D9 Histidine kinase FOC91_RS21320 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS21335 ENOG4105IIP Membrane FOC91_RS21345 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC91_RS21350 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC91_RS21405 ENOG4105F7F Chaperone FOC91_RS21420 ENOG41085FC arsR family transcriptional regulator FOC91_RS21425 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC91_RS21430 ENOG4105D6J arsenicaL-resistance protein FOC91_RS21460 ENOG4105DIK (ABC) transporter FOC91_RS21465 ENOG4105CC5 ABC transporter FOC91_RS21470 ENOG4105DSE periplasmic solute binding protein FOC91_RS21475 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) FOC91_RS21480 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC91_RS21490 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC91_RS21505 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC91_RS21510 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC91_RS21540 ENOG4108606 TspO/MBR family FOC91_RS21560 ENOG4105YA8 Transcriptional regulator FOC91_RS21565 ENOG4106A3M Cytochrome p-450 FOC91_RS21610 ENOG41061CK Antibiotic biosynthesis monooxygenase FOC91_RS21615 ENOG4105CGH 5'-nucleotidase FOC91_RS21630 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC91_RS21645 ENOG4105E2A Dehydrogenase FOC91_RS21710 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC91_RS21735 ENOG4105DWD nucleoside recognition domain protein FOC91_RS21750 ENOG4105FDT acyl-CoA dehydrogenase FOC91_RS21760 ENOG4108ZHR arsR family transcriptional regulator FOC91_RS21765 ENOG4108ZRV stage ii sporulation protein p FOC91_RS21770 ENOG4106N3A copper homeostasis protein cutc FOC91_RS21780 ENOG4107258 Transcriptional regulator FOC91_RS21785 ENOG4105P4J Allophanate hydrolase, subunit 1 FOC91_RS21820 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FOC91_RS21825 ENOG4107RF6 penicillin-binding protein FOC91_RS21855 ENOG4105F1N DNA alkylation repair FOC91_RS21865 ENOG4108IQI permease FOC91_RS21875 ENOG410635A Membrane FOC91_RS21960 ENOG4108XET gCN5-related N-acetyltransferase FOC91_RS21990 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) FOC91_RS22005 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS22040 ENOG4105FS7 Transcriptional regulator FOC91_RS22045 ENOG4108TVJ Nitroreductase FOC91_RS22085 ENOG4105CH6 catalase FOC91_RS22090 ENOG4105C8Y Acetylornithine aminotransferase FOC91_RS22100 ENOG4105CKK Glycosyl transferase, family 2 FOC91_RS22125 ENOG4105CSH Transporter FOC91_RS22140 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC91_RS22165 ENOG41068WN FOC91_RS22190 ENOG4108WCX response regulator FOC91_RS22200 ENOG41090T1 Membrane FOC91_RS22215 ENOG4105VMP Transcriptional regulator FOC91_RS22225 ENOG4105G6Z alkaline phosphatase FOC91_RS22230 ENOG4105ECK Fatty Acid Desaturase FOC91_RS22235 ENOG4105E0Y RtcB Protein FOC91_RS22245 ENOG4107258 Transcriptional regulator FOC91_RS22255 ENOG4105II7 pyrroline-5-carboxylate reductase FOC91_RS22260 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) FOC91_RS22290 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC91_RS22315 ENOG41061GT Aldolase FOC91_RS22325 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) FOC91_RS22330 ENOG4105DKT Transcriptional regulator FOC91_RS22340 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC91_RS22350 ENOG4105D4B ABC, transporter FOC91_RS22365 ENOG4108JUB Transcriptional regulator FOC91_RS22370 ENOG4105J5T Amp-dependent synthetase and ligase FOC91_RS22375 ENOG4105E39 Enoyl-CoA hydratase FOC91_RS22380 ENOG4105CY2 Citrate transporter FOC91_RS22390 ENOG41069ER domain protein FOC91_RS22405 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FOC91_RS22425 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC91_RS22435 ENOG4105CIH Imidazole acetol-phosphate transaminase FOC91_RS22455 ENOG41082JN Transcriptional regulator FOC91_RS22460 ENOG4105EYF MMPL domain protein FOC91_RS22470 ENOG4105C5H ABC transporter FOC91_RS22475 ENOG4105E0M Sulfatase FOC91_RS22480 ENOG4108ZCF integral membrane protein FOC91_RS22550 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC91_RS22570 ENOG4105E09 nadh pyrophosphatase FOC91_RS22585 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC91_RS22590 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC91_RS22595 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC91_RS22605 ENOG4105C02 permease FOC91_RS22650 ENOG4105DVE abc transporter atp-binding protein FOC91_RS22665 ENOG4108ZMI UPF0477 protein FOC91_RS22680 ENOG4105CHM Aminotransferase FOC91_RS22710 ENOG41089UC methyltransferase, type 11 FOC91_RS22725 ENOG4107BMA Transglycosylase associated protein FOC91_RS22745 ENOG4106K7D Major facilitator family transporter FOC91_RS22750 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC91_RS22805 ENOG4105EPR degv family FOC91_RS22815 ENOG4105DVH amino acid FOC91_RS22820 ENOG4105DPN Oligoendopeptidase f FOC91_RS22850 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS22855 ENOG4105BZU Histidine kinase FOC91_RS22860 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC91_RS22905 ENOG4105DTQ mandelate racemase muconate lactonizing FOC91_RS22920 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) FOC91_RS22925 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC91_RS22940 ENOG4107T5V SNARE associated Golgi FOC91_RS22970 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein FOC91_RS22980 ENOG41080HI glycine oxidase FOC91_RS22985 ENOG4105CTU Proline racemase FOC91_RS22990 ENOG4105CTU Proline racemase FOC91_RS22995 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC91_RS23000 ENOG4105C26 Dehydrogenase FOC91_RS23005 ENOG4105BZG amino acid carrier protein FOC91_RS23025 ENOG4108M1A Chitin-binding protein FOC91_RS23075 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC91_RS23095 ENOG4105EEM helicase FOC91_RS23115 ENOG4108Z7F N-acetyltransferase FOC91_RS23145 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC91_RS23150 ENOG4107YB6 acetyltransferase, (GNAT) family FOC91_RS23155 ENOG4105MSB protein, conserved in bacteria FOC91_RS23160 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC91_RS23175 ENOG4108M1A Chitin-binding protein FOC91_RS23180 ENOG41082BV acetyltransferase FOC91_RS23210 ENOG4108IJ7 Glycine betaine FOC91_RS23215 ENOG4107SQ8 Glycine betaine FOC91_RS23240 ENOG4108TIT dATP pyrophosphohydrolase FOC91_RS23250 ENOG4105DBI uridine monophosphokinase FOC91_RS23255 ENOG4105RHY Pfam:UPF0157 FOC91_RS23260 ENOG4105E1F short-chain dehydrogenase reductase FOC91_RS23270 ENOG4107RUY (E1 component), alpha subunit FOC91_RS23280 ENOG4107QKR Dehydrogenase FOC91_RS23300 ENOG41062ES Transcriptional regulator FOC91_RS23320 ENOG4105E98 transcriptional regulator DeoR family FOC91_RS23325 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC91_RS23340 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC91_RS23375 ENOG4107Z3H Transcriptional regulator, TetR family FOC91_RS23410 ENOG4105MSI germination protein ypeb FOC91_RS23465 ENOG4105FDR Membrane FOC91_RS23475 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC91_RS23480 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) FOC91_RS23505 ENOG4108IUM Glycogen debranching enzyme FOC91_RS23525 ENOG4105PAD Hydrolase FOC91_RS23550 ENOG4107VFR oxidoreductase FOC91_RS23585 ENOG4105PKS Excinuclease abc c subunit domain protein FOC91_RS23620 ENOG4105KWG Pfam:DUF1696 FOC91_RS23625 ENOG4108NRW Phospholipase, patatin family FOC91_RS23645 ENOG4108XI2 Domain of unknown function (DUF1963) FOC91_RS23655 ENOG4107TB6 phosphoglycerate mutase FOC91_RS23680 ENOG4108Z4K mutator MutT protein FOC91_RS23685 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC91_RS23690 ENOG4105E09 nadh pyrophosphatase FOC91_RS23695 ENOG4105FCD Major Facilitator FOC91_RS23730 ENOG4107Y9U Membrane FOC91_RS23755 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC91_RS23770 ENOG4107Y80 Major Facilitator superfamily FOC91_RS23790 ENOG4108V4B ThiJ pfpI FOC91_RS23825 ENOG4105FQP Beta-lactamase FOC91_RS23835 ENOG4105CHR reductase FOC91_RS23840 ENOG4108IG5 Transcriptional regulator FOC91_RS23845 ENOG4105CJN penicillin-binding protein FOC91_RS23850 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC91_RS23855 ENOG4105CB2 alcohol dehydrogenase FOC91_RS23860 ENOG4105RHY Pfam:UPF0157 FOC91_RS23870 ENOG4108HGU Histidine kinase FOC91_RS23905 ENOG4107RF6 penicillin-binding protein FOC91_RS23910 ENOG4105BZU Histidine kinase FOC91_RS23915 ENOG410667J hydrolase FOC91_RS24025 ENOG4105ETU transcriptional activator (TenA FOC91_RS24110 ENOG4105DK7 lysyl-tRNA synthetase FOC91_RS24120 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FOC91_RS24140 ENOG4105CPQ Dehydrogenase FOC91_RS24180 ENOG4105CUV Homoserine Kinase FOC91_RS24200 ENOG4107Y80 Major Facilitator superfamily FOC91_RS24225 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC91_RS24225 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC91_RS24265 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC91_RS24275 ENOG4105T9C HD domain FOC91_RS24305 ENOG4105DBI uridine monophosphokinase FOC91_RS24310 ENOG4105WCN acetyltransferase FOC91_RS24320 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC91_RS24325 ENOG4107QX3 carboxylase FOC91_RS24330 ENOG4105E39 Enoyl-CoA hydratase FOC91_RS24335 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC91_RS24340 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC91_RS24345 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC91_RS24350 ENOG4105C1G acyl-Coa dehydrogenase FOC91_RS24375 ENOG4105D7V transposase FOC91_RS24380 ENOG4107RGJ metallophosphoesterase FOC91_RS24390 ENOG4107RF6 penicillin-binding protein FOC91_RS24395 ENOG4107RF6 penicillin-binding protein FOC91_RS24405 ENOG4105EMN RNA polymerase sigma factor FOC91_RS24420 ENOG4105CIN aminoacyl-histidine dipeptidase FOC91_RS24455 ENOG41090HR transcriptional regulator FOC91_RS24555 ENOG41088CC tellurite resistance protein tehB FOC91_RS24575 ENOG4108RZE Tetr family transcriptional regulator FOC91_RS24590 ENOG4105C1J atp-dependent rna helicase FOC91_RS24605 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC91_RS24640 ENOG4107STF Involved in phosphonate degradation (By similarity) FOC91_RS24650 ENOG4105RD7 BadF BadG BcrA BcrD FOC91_RS24675 ENOG4105F32 YngK protein FOC91_RS24700 ENOG4108KPJ rna polymerase sigma factor FOC91_RS24705 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B FOC91_RS24715 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC91_RS24745 ENOG4108JCI Transcriptional regulator FOC91_RS24765 ENOG4105BZ1 (ABC) transporter FOC91_RS24770 ENOG4105BZ1 (ABC) transporter FOC91_RS24785 ENOG4108RPX mosc domain containing protein FOC91_RS24790 ENOG4105DND Transcriptional regulator FOC91_RS24805 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC91_RS24810 ENOG4107V2S Transcriptional regulator FOC91_RS25035 ENOG4107QPV Serine Threonine protein kinase FOC91_RS25050 ENOG4105KRN Transcriptional regulator, abrb family FOC91_RS25125 ENOG4105C2M dna polymerase I FOC91_RS25130 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC91_RS25245 ENOG4105VEQ Cold shock protein FOC91_RS25255 ENOG41068WN FOC91_RS25260 ENOG41089UC methyltransferase, type 11 FOC91_RS25270 ENOG4105C1Q protoporphyrinogen oxidase FOC91_RS25300 ENOG4105WCN acetyltransferase FOC91_RS25325 ENOG4105EYF MMPL domain protein FOC91_RS25335 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC91_RS25350 ENOG41081I9 integral membrane protein FOC91_RS25380 ENOG4108D32 Methyltransferase FOC91_RS25410 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC91_RS25420 ENOG4105C19 ABC transporter FOC91_RS25430 ENOG4105C22 threonyL-tRNA synthetase FOC91_RS25435 ENOG4105FE9 pseudouridine synthase FOC91_RS25455 ENOG4105BZG amino acid carrier protein FOC91_RS25475 ENOG4105K70 DNA-binding protein FOC91_RS25490 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC91_RS25495 ENOG4105WQT MbtH domain protein FOC91_RS25500 ENOG4105CEY Amp-dependent synthetase and ligase FOC91_RS25505 ENOG4105WQI isochorismatase FOC91_RS25510 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC91_RS25515 ENOG4105E4F Isochorismate synthase FOC91_RS25520 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC91_RS25525 ENOG4105FCD Major Facilitator FOC91_RS25550 ENOG4107RFY SbcCD D subunit FOC91_RS25565 ENOG4105E39 Enoyl-CoA hydratase FOC91_RS25570 ENOG4105N14 lysine exporter protein LysE YggA FOC91_RS25580 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC91_RS25585 ENOG4105C1G acyl-Coa dehydrogenase FOC91_RS25590 ENOG4105CR4 methylisocitrate lyase FOC91_RS25595 ENOG4105DXD 2-methylcitrate dehydratase FOC91_RS25605 ENOG4105W8X HesB YadR YfhF-family protein FOC91_RS25610 ENOG4105CZM Major Facilitator FOC91_RS25620 ENOG4105BZ4 penicillin-binding protein FOC91_RS25670 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC91_RS25730 ENOG4105SZ6 Thioredoxin FOC91_RS25740 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC91_RS25745 ENOG4108N23 SpoOM-related protein FOC91_RS25785 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC91_RS25790 ENOG4108JUB Transcriptional regulator FOC91_RS25795 ENOG4108TSC N-acetyltransferase FOC91_RS25800 ENOG4107S4Y M20 DapE family protein YgeY FOC91_RS25815 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC91_RS25840 ENOG4105C37 (CBS) domain FOC91_RS25875 ENOG4105E90 ABC transporter FOC91_RS25880 ENOG4108IJ8 ABC transporter FOC91_RS25910 ENOG4105CMG Carbohydrate kinase FOC91_RS25915 ENOG4105CMG Carbohydrate kinase FOC91_RS25950 ENOG4105WH1 Two component transcriptional regulator luxr family FOC91_RS25955 ENOG4105BZU Histidine kinase FOC91_RS25960 ENOG4105D8X mechanosensitive ion channel FOC91_RS25995 ENOG4105F0I Aminotransferase FOC91_RS26000 ENOG4108MES Periplasmic binding protein FOC91_RS26020 ENOG4105CAQ asparagine synthetase FOC91_RS26025 ENOG4107Y70 Heat shock protein FOC91_RS26030 ENOG4108KF3 Electron transport protein SCO1 SenC FOC91_RS26035 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC91_RS26040 ENOG4108RCR degv family FOC91_RS26050 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC91_RS26060 ENOG4108UT2 hemolysin iii FOC91_RS26065 ENOG4105E9Q Acyl-transferase FOC91_RS26075 ENOG4107RVG penicillin-binding protein FOC91_RS26095 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC91_RS26115 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC91_RS26140 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOC91_RS26145 ENOG4105KD7 acetyltransferase FOC91_RS26160 ENOG4105C0A alcohol dehydrogenase FOC91_RS26165 ENOG4105CY2 Citrate transporter FOC91_RS26170 ENOG4107XGZ Hydrolase FOC91_RS26190 ENOG4105C8J )-transporter FOC91_RS26205 ENOG41062D9 Histidine kinase FOC91_RS26210 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC91_RS26215 ENOG4107QPK )-transporter FOC91_RS26220 ENOG4105BZW Glycerate kinase FOC91_RS26340 ENOG4107EV6 Inherit from COG: YD repeat protein FOC91_RS26365 ENOG4105EC2 ftsk spoIIIe FOC91_RS26385 ENOG4105C5S asparaginyl-tRNA synthetase FOC91_RS26430 ENOG4107YX5 Pfam:DUF548 FOC91_RS26460 ENOG4108UUM single-stranded DNA-binding protein FOC91_RS26475 ENOG4105C5H ABC transporter FOC91_RS26540 ENOG4105MCT stage V sporulation protein S FOC91_RS26575 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC91_RS26580 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC91_RS26585 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC91_RS26590 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC91_RS26595 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC91_RS26600 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC91_RS26620 ENOG4108ZAF Molybdopterin FOC91_RS26625 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC91_RS26630 ENOG4105D06 uba thif-type nad fad binding protein FOC91_RS26635 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC91_RS26640 ENOG4107V6Q Cyclic nucleotide-binding domain FOC91_RS26650 ENOG4105R3A Nitrate reductase FOC91_RS26655 ENOG4108IUE nitrate reductase beta subunit FOC91_RS26675 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC91_RS26690 ENOG4108V06 Glutathione peroxidase FOC91_RS26700 ENOG4105CNW domain protein FOC91_RS26715 ENOG4105EMN RNA polymerase sigma factor FOC91_RS26720 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC91_RS26730 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC91_RS26755 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC91_RS26780 ENOG4105KBJ sporulation protein ytfj FOC91_RS26860 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC91_RS26890 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS26895 ENOG4108JYZ YitT family FOC91_RS26900 ENOG41087PP glycosyltransferase MGT family FOC91_RS26920 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC91_RS26930 ENOG4108X4Q Hydrolase FOC91_RS26940 ENOG41069HH 4-oxalocrotonate tautomerase FOC91_RS26960 ENOG4105IKQ hydratase FOC91_RS26970 ENOG4105KME endoribonuclease L-psp FOC91_RS26985 ENOG4105U1N riboflavin FOC91_RS26995 ENOG4105EFA 4-hydroxyphenylacetate FOC91_RS27015 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC91_RS27025 ENOG4108VXD carboxy-peptidase FOC91_RS27035 ENOG4108ZRV stage ii sporulation protein p FOC91_RS27055 ENOG4108Z7R Chaperone CsaA FOC91_RS27075 ENOG4105C37 (CBS) domain FOC91_RS27080 ENOG4105SXS Protein of unknown function (DUF456) FOC91_RS27100 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC91_RS27110 ENOG4108S4H thioesterase Superfamily protein FOC91_RS27120 ENOG4108PJD permease FOC91_RS27135 ENOG4107T5V SNARE associated Golgi FOC91_RS27155 ENOG4105CVJ phosphoglycerate mutase FOC91_RS27180 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC91_RS27190 ENOG4105K4T epimerase FOC91_RS27200 ENOG4105DSE periplasmic solute binding protein FOC91_RS27205 ENOG4108IBT Inherit from COG: transposase FOC91_RS27225 ENOG4105CKI cobalamin synthesis protein FOC91_RS27230 ENOG4107QM2 Aldo Keto reductase FOC91_RS27250 ENOG4105DEN Luciferase family FOC91_RS27265 ENOG4108WPJ Ferritin-like domain FOC91_RS27270 ENOG4108K88 Membrane FOC91_RS27285 ENOG4105C8Q Methyl-accepting chemotaxis FOC91_RS27310 ENOG4107XZQ multidrug resistance protein FOC91_RS27315 ENOG4107SET aldo keto reductase FOC91_RS27320 ENOG4105YVS arsR family transcriptional regulator FOC91_RS27330 ENOG4105KRN Transcriptional regulator, abrb family FOC91_RS27380 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC91_RS27385 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC91_RS27395 ENOG4105YWU small acid-soluble spore protein FOC91_RS27400 ENOG4108WBH protein TIM barrel FOC91_RS27415 ENOG4105CEY Amp-dependent synthetase and ligase FOC91_RS27420 ENOG4105DUU IucA IucC family protein FOC91_RS27430 ENOG4105VRR gCN5-related N-acetyltransferase FOC91_RS27435 ENOG4105KT7 mgtC SapB transporter FOC91_RS27450 ENOG4105BZU Histidine kinase FOC91_RS27455 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS27465 ENOG4108KGH TRANSCRIPTIONal FOC91_RS27490 ENOG4105D6E homoserine dehydrogenase FOC91_RS27515 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC91_RS27535 ENOG4105BZU Histidine kinase FOC91_RS27540 ENOG4105EFI regulatoR FOC91_RS27545 ENOG4105BZ1 (ABC) transporter FOC91_RS27590 ENOG4108JJ8 (ABC) transporter FOC91_RS27595 ENOG4108JJ9 ABC, transporter FOC91_RS27600 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC91_RS27605 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC91_RS27635 ENOG4105EGI Transcriptional regulator FOC91_RS27645 ENOG4105C32 Amino acid ABC transporter (Permease) FOC91_RS27650 ENOG4108IV0 ABC, transporter FOC91_RS27655 ENOG4105C0Z ABC transporter FOC91_RS27665 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC91_RS27670 ENOG4108Z7G MaoC domain protein dehydratase FOC91_RS27690 ENOG4105CKI cobalamin synthesis protein FOC91_RS27705 ENOG4106F5Q Membrane FOC91_RS27710 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC91_RS27715 ENOG4108TVJ Nitroreductase FOC91_RS27720 ENOG4107ZXU DSBA oxidoreductase FOC91_RS27725 ENOG4108Z40 Transcriptional regulator FOC91_RS27730 ENOG4105GZI Transcriptional regulator FOC91_RS27735 ENOG4107RT3 EamA-like transporter family FOC91_RS27745 ENOG4105KTB nuclear export factor GLE1 FOC91_RS27750 ENOG4108T5E Copper resistance protein FOC91_RS27820 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC91_RS27825 ENOG4105DY8 decarboxylase FOC91_RS27890 ENOG4107R16 Multicopper oxidase FOC91_RS27895 ENOG4107RAQ aminopeptidase FOC91_RS27925 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC91_RS27930 ENOG4105D9N nucleoside FOC91_RS27940 ENOG4107RHR regulatoR FOC91_RS27950 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC91_RS27995 ENOG4105C0X amino acid FOC91_RS28000 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FOC91_RS28015 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC91_RS28040 ENOG41068WN FOC91_RS28085 ENOG4108IBT Inherit from COG: transposase FOC91_RS28105 ENOG4105CYC Transferase FOC91_RS28110 ENOG4105DY9 regulatoR FOC91_RS28130 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC91_RS28135 ENOG4105C6X Major Facilitator FOC91_RS28160 ENOG4105C7B Threonine dehydratase FOC91_RS28170 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FOC91_RS28180 ENOG4105C7K acetolactate synthase FOC91_RS28185 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC91_RS28190 ENOG4105CHR reductase FOC91_RS28195 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC91_RS28210 ENOG4106KE4 Dehydrogenase FOC91_RS28225 ENOG4105H67 Protein of unknown function (DUF421) FOC91_RS28230 ENOG4105X5K response regulator receiver protein FOC91_RS28240 ENOG4105C8J )-transporter FOC91_RS28260 ENOG4105C6T cysteine synthase FOC91_RS28265 ENOG4105EU0 Major facilitator Superfamily FOC91_RS28275 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC91_RS28290 ENOG4105DXI Major Facilitator superfamily FOC91_RS28295 ENOG4105CSR polyphosphate kinase 2 FOC91_RS28345 ENOG4105FVX FOC91_RS28410 ENOG4105C6K Malic enzyme FOC91_RS28415 ENOG4108IJ0 Aspartate ammonia-lyase FOC91_RS28425 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC91_RS28445 ENOG4105CJ1 ABC, transporter FOC91_RS28480 ENOG4106BRA Membrane FOC91_RS28510 ENOG4107QIV Cytochrome c biogenesis protein FOC91_RS28530 ENOG4105EC3 peptidase S51, dipeptidase E FOC91_RS28535 ENOG4107QJQ Mate efflux family protein FOC91_RS28550 ENOG4105C9Q fumarate hydratase class II FOC91_RS28555 ENOG4105DFD Na H antiporter FOC91_RS28570 ENOG4108PJD permease FOC91_RS28575 ENOG4105CKI cobalamin synthesis protein FOC91_RS28580 ENOG4108UZ3 Transporter FOC91_RS28585 ENOG4105DRR Transcriptional regulator, GntR family FOC91_RS28595 ENOG4105PGM cation diffusion facilitator family transporter FOC91_RS28615 ENOG4105CAQ asparagine synthetase FOC91_RS28625 ENOG4105K56 Transcriptional regulator FOC91_RS28640 ENOG4105CVJ phosphoglycerate mutase FOC91_RS28690 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr FOC91_RS28705 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FOC91_RS28710 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC91_RS28720 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC91_RS28750 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC91_RS28780 ENOG41062JF Transcriptional regulator FOC91_RS28805 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC91_RS28810 ENOG4105KTQ flagellar basal-body rod protein FOC91_RS28815 ENOG4105FZW flagellar biosynthesis regulator FlhF FOC91_RS28820 ENOG4105D7B Flagellar biosynthesis protein flha FOC91_RS28825 ENOG4105D00 flagellar biosynthetic protein flhB FOC91_RS28835 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC91_RS28840 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC91_RS28850 ENOG4105DD5 Flagellar motor switch protein FOC91_RS28855 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC91_RS28865 ENOG4105E4C Lytic transglycosylase catalytic FOC91_RS28870 ENOG4105I03 Flagellin FOC91_RS28875 ENOG4105I03 Flagellin FOC91_RS28885 ENOG4107R88 Chemotaxis protein (CheV) FOC91_RS28900 ENOG4105BZE flagellar hook protein, FlgE FOC91_RS28930 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC91_RS28935 ENOG4107U2N Flagellar M-ring protein FOC91_RS28945 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC91_RS28950 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC91_RS28965 ENOG4105DTS flagellar hook-associated FOC91_RS28970 ENOG4105DTJ flagellar hook-associated protein FOC91_RS28975 ENOG4105E1Q flagellar hook-associated protein FOC91_RS28995 ENOG4105BZU Histidine kinase FOC91_RS29010 ENOG4105DD5 Flagellar motor switch protein FOC91_RS29015 ENOG4105CBS Chea signal transduction histidine kinase FOC91_RS29020 ENOG4107YTP response regulator receiver protein FOC91_RS29025 ENOG4105ER2 Ompa motb domain protein FOC91_RS29030 ENOG4107R0U MotA TolQ exbB proton channel FOC91_RS29040 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC91_RS29095 ENOG41080C8 DUF218 domain FOC91_RS29100 ENOG4105H67 Protein of unknown function (DUF421) FOC91_RS29110 ENOG4108Z5V transcriptional regulator, merr family FOC91_RS29115 ENOG4105CN5 Metallo-Beta-Lactamase FOC91_RS29120 ENOG4107RWR Sodium hydrogen exchanger FOC91_RS29130 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC91_RS29195 ENOG41081VK Ribonuclease FOC91_RS29215 ENOG4108SZE gCN5-related N-acetyltransferase FOC91_RS29285 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase