locus-tag class description FOC92_RS00010 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC92_RS00015 ENOG4107QKG PfaD family FOC92_RS00020 ENOG4108151 Beta-lactamase domain protein FOC92_RS00045 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC92_RS00125 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC92_RS00150 ENOG41067FT ParB-like nuclease domain FOC92_RS00180 ENOG4105TRI Hydrolase FOC92_RS00220 ENOG4105IBP Cyclic peptide transporter FOC92_RS00225 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC92_RS00230 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS00245 ENOG4105X96 Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity) FOC92_RS00250 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC92_RS00265 ENOG4105C1G acyl-Coa dehydrogenase FOC92_RS00275 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS00285 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS00285 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS00300 ENOG4107SDT Homocitrate synthase FOC92_RS00320 ENOG4105CUZ uba thif-type nad fad binding protein FOC92_RS00350 ENOG4107QJQ Mate efflux family protein FOC92_RS00355 ENOG4108WC5 Alpha Beta Hydrolase Fold protein FOC92_RS00360 ENOG41087PP glycosyltransferase MGT family FOC92_RS00365 ENOG4105KNA -acetyltransferase FOC92_RS00380 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) FOC92_RS00385 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) FOC92_RS00395 ENOG41080TC multidrug resistance protein FOC92_RS00420 ENOG4107SET aldo keto reductase FOC92_RS00440 ENOG4105CFF transcriptional regulator FOC92_RS00480 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FOC92_RS00495 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation FOC92_RS00535 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC92_RS00590 ENOG4105K70 DNA-binding protein FOC92_RS00610 ENOG4107JM4 Tetratricopeptide repeat FOC92_RS00615 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC92_RS00690 ENOG4105CAQ asparagine synthetase FOC92_RS00695 ENOG4108RZE Tetr family transcriptional regulator FOC92_RS00785 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC92_RS00800 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase FOC92_RS00805 ENOG4105DR5 peptidase FOC92_RS00810 ENOG41065S2 pneumococcal vaccine antigen FOC92_RS00900 ENOG4105E4C Lytic transglycosylase catalytic FOC92_RS00910 ENOG41069ER domain protein FOC92_RS00920 ENOG4107JM4 Tetratricopeptide repeat FOC92_RS00985 ENOG4105CJW magnesium transporter FOC92_RS01135 ENOG4105DQ6 Transposase FOC92_RS01205 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC92_RS01235 ENOG4105D7V transposase FOC92_RS01255 ENOG4105KRN Transcriptional regulator, abrb family FOC92_RS01320 ENOG4105D7V transposase FOC92_RS01345 ENOG4108IQI permease FOC92_RS01350 ENOG4108J5H Homocysteine s-methyltransferase FOC92_RS01360 ENOG4105BZU Histidine kinase FOC92_RS01365 ENOG4105C19 ABC transporter FOC92_RS01375 ENOG4105DNP FAD linked oxidase domain protein FOC92_RS01415 ENOG4105BZ4 penicillin-binding protein FOC92_RS01425 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC92_RS01445 ENOG4105DVH amino acid FOC92_RS01460 ENOG4105MZU cell filamentation protein FOC92_RS01465 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC92_RS01480 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC92_RS01490 ENOG4106A3M Cytochrome p-450 FOC92_RS01510 ENOG4107RA9 decarboxylase FOC92_RS01555 ENOG4107SCK Monooxygenase FOC92_RS01560 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC92_RS01565 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC92_RS01570 ENOG4107QHE Choloylglycine hydrolase FOC92_RS01580 ENOG4108NHD germination protein FOC92_RS01590 ENOG4105VEQ Cold shock protein FOC92_RS01610 ENOG4108VJ1 Transcriptional regulator (CarD family FOC92_RS01640 ENOG4105DRR Transcriptional regulator, GntR family FOC92_RS01665 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) FOC92_RS01675 ENOG4108JJA ABC, transporter FOC92_RS01705 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS01745 ENOG4105PF9 Transcriptional regulator FOC92_RS01750 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS01755 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS01760 ENOG4107SQU synthase FOC92_RS01765 ENOG4107SQU synthase FOC92_RS01770 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS01775 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS01780 ENOG4107SQU synthase FOC92_RS01785 ENOG4105C0W non-ribosomal peptide synthetase FOC92_RS01800 ENOG4108KS4 Spore coat protein FOC92_RS01805 ENOG4107SBE Glycosyl transferase (Group 1 FOC92_RS01825 ENOG4107SBE Glycosyl transferase (Group 1 FOC92_RS01830 ENOG4108IAJ Nad-dependent epimerase dehydratase FOC92_RS02060 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC92_RS02095 ENOG4105F6J Alpha beta hydrolase fold FOC92_RS02105 ENOG4105F6J Alpha beta hydrolase fold FOC92_RS02130 ENOG4105XT2 Transcriptional regulator FOC92_RS02155 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) FOC92_RS02165 ENOG4107RSM transcriptional regulator FOC92_RS02170 ENOG4107AYK membrAne FOC92_RS02175 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC92_RS02185 ENOG4105K70 DNA-binding protein FOC92_RS02205 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC92_RS02240 ENOG4108W2Y isochorismatase FOC92_RS02260 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) FOC92_RS02270 ENOG4105ST3 Transcriptional regulator FOC92_RS02360 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC92_RS02365 ENOG4108BUD transposase FOC92_RS02375 ENOG4105C19 ABC transporter FOC92_RS02390 ENOG41081I9 integral membrane protein FOC92_RS02405 ENOG4108BUD transposase FOC92_RS02415 ENOG410780I phosphoprotein phosphatase activity FOC92_RS02495 ENOG4105NA0 Transcriptional regulator FOC92_RS02500 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC92_RS02545 ENOG4107SWG transcriptional regulator MERR family FOC92_RS02550 ENOG4105KNA -acetyltransferase FOC92_RS02560 ENOG4105CE7 Amidase, hydantoinase carbamoylase family FOC92_RS02570 ENOG4105G9B Transcriptional regulator FOC92_RS02680 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) FOC92_RS02695 ENOG4105BZ1 (ABC) transporter FOC92_RS02705 ENOG4108WUH Transcriptional regulator, TetR family FOC92_RS02725 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS02735 ENOG4107RN3 metallophosphoesterase FOC92_RS02770 ENOG4108VHC Short-chain dehydrogenase reductase Sdr FOC92_RS02775 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS02860 ENOG4105D7V transposase FOC92_RS02895 ENOG4108IAJ Nad-dependent epimerase dehydratase FOC92_RS02900 ENOG4107QQG Dehydrogenase FOC92_RS02960 ENOG4105CK5 oxidoreductase FOC92_RS02965 ENOG4105CK5 oxidoreductase FOC92_RS02985 ENOG4105CNU cell division protein FtsK FOC92_RS03145 ENOG4105CID antiterminator FOC92_RS03150 ENOG4105C5Y PTS System FOC92_RS03155 ENOG4105CS2 ec 3.2.1.21 FOC92_RS03255 ENOG4105EKQ RNA-directed DNA polymerase FOC92_RS03295 ENOG4105D7V transposase FOC92_RS03320 ENOG4105WKZ CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity) FOC92_RS03335 ENOG4105DHF Membrane FOC92_RS03405 ENOG4105CSH Transporter FOC92_RS03415 ENOG4105CKK Glycosyl transferase, family 2 FOC92_RS03440 ENOG4105C8Y Acetylornithine aminotransferase FOC92_RS03485 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC92_RS03570 ENOG4108TVJ Nitroreductase FOC92_RS03575 ENOG4105FS7 Transcriptional regulator FOC92_RS03615 ENOG4108S5C Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell (By similarity) FOC92_RS03620 ENOG4108XET gCN5-related N-acetyltransferase FOC92_RS03635 ENOG4108PCN EamA-like transporter family FOC92_RS03680 ENOG410635A Membrane FOC92_RS03690 ENOG4108IQI permease FOC92_RS03700 ENOG4105F1N DNA alkylation repair FOC92_RS03735 ENOG4107RF6 penicillin-binding protein FOC92_RS03740 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) FOC92_RS03760 ENOG4105E7W lamb ycsf family protein FOC92_RS03770 ENOG4105P4J Allophanate hydrolase, subunit 1 FOC92_RS03775 ENOG4107258 Transcriptional regulator FOC92_RS03785 ENOG4106N3A copper homeostasis protein cutc FOC92_RS03790 ENOG4108ZHR arsR family transcriptional regulator FOC92_RS03800 ENOG4105FDT acyl-CoA dehydrogenase FOC92_RS03815 ENOG4105DWD nucleoside recognition domain protein FOC92_RS03850 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) FOC92_RS03875 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC92_RS03900 ENOG4105E2A Dehydrogenase FOC92_RS03910 ENOG4108IJ0 Aspartate ammonia-lyase FOC92_RS03915 ENOG4105HDK L-asparaginase FOC92_RS03920 ENOG4108IMY Transcriptional regulator FOC92_RS03945 ENOG4108B31 Spore germination protein FOC92_RS03955 ENOG4105BZU Histidine kinase FOC92_RS03980 ENOG41075H3 AraC family transcriptional regulator FOC92_RS03990 ENOG4105YWU small acid-soluble spore protein FOC92_RS03995 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC92_RS04000 ENOG4105CUB amino acid FOC92_RS04005 ENOG4105II7 pyrroline-5-carboxylate reductase FOC92_RS04010 ENOG4108NHD germination protein FOC92_RS04015 ENOG4108Q8B Spore germination protein FOC92_RS04065 ENOG4105CGH 5'-nucleotidase FOC92_RS04075 ENOG4105CHJ isochorismatase hydrolase FOC92_RS04100 ENOG4105EQ0 Major Facilitator superfamily FOC92_RS04155 ENOG4105F6J Alpha beta hydrolase fold FOC92_RS04170 ENOG4108606 TspO/MBR family FOC92_RS04175 ENOG4105CVP deoxyribo-dipyrimidine photolyase FOC92_RS04190 ENOG4108TWJ NADH dehydrogenase subunit 5 FOC92_RS04195 ENOG4105GPN Uncharacterized conserved protein (DUF2294) FOC92_RS04200 ENOG4105F27 Major Facilitator FOC92_RS04205 ENOG4106P55 Transcriptional regulator FOC92_RS04220 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOC92_RS04225 ENOG4105BZU Histidine kinase FOC92_RS04230 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS04255 ENOG4108VJ1 Transcriptional regulator (CarD family FOC92_RS04270 ENOG4105FR1 rard protein FOC92_RS04305 ENOG41062ES Transcriptional regulator FOC92_RS04310 ENOG4105C57 major facilitator superfamily FOC92_RS04325 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC92_RS04330 ENOG4105ECQ AraC Family Transcriptional Regulator FOC92_RS04335 ENOG4105Z7P Acetyltransferase (GNAT) family FOC92_RS04345 ENOG4105D6J arsenicaL-resistance protein FOC92_RS04350 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC92_RS04355 ENOG41085FC arsR family transcriptional regulator FOC92_RS04380 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC92_RS04405 ENOG4107P5I polyketide synthase FOC92_RS04410 ENOG4108IG5 Transcriptional regulator FOC92_RS04415 ENOG4108JGH Tetr family transcriptional regulator FOC92_RS04420 ENOG4105EQ0 Major Facilitator superfamily FOC92_RS04440 ENOG4105F27 Major Facilitator FOC92_RS04445 ENOG4105M4P Tetr family transcriptional regulator FOC92_RS04450 ENOG4105CYX Short-chain dehydrogenase reductase Sdr FOC92_RS04455 ENOG4108YXU transcriptional regulator AsnC family FOC92_RS04550 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) FOC92_RS04555 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS04570 ENOG4105K6H D-cysteine desulfhydrase FOC92_RS04580 ENOG4105E0Y RtcB Protein FOC92_RS04590 ENOG4105JQZ Methyltransferase FOC92_RS04610 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) FOC92_RS04630 ENOG4105BZU Histidine kinase FOC92_RS04640 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC92_RS04675 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) FOC92_RS04710 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC92_RS04830 ENOG4108VXD carboxy-peptidase FOC92_RS04835 ENOG4105PNM synthesis protein FOC92_RS04845 ENOG4108ISG Major Facilitator FOC92_RS04860 ENOG4107MII Sugar-specific transcriptional regulator TrmB FOC92_RS04865 ENOG4105CZM Major Facilitator FOC92_RS04880 ENOG4105CRW Short chain fatty acid transporter FOC92_RS04890 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC92_RS04950 ENOG4108K8S endonuclease I FOC92_RS04970 ENOG4108Z66 YbaK ebsC protein FOC92_RS04975 ENOG4105CUT histidyl-tRNA synthetase FOC92_RS04990 ENOG4105KVH Transcriptional regulator FOC92_RS04995 ENOG4108RCM Nitroreductase FOC92_RS05025 ENOG4108PSK reductase FOC92_RS05140 ENOG4105EV4 Multidrug resistance protein mdtH FOC92_RS05170 ENOG4105C37 (CBS) domain FOC92_RS05185 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FOC92_RS05190 ENOG4105FAW cDP-glucose 4,6-dehydratase FOC92_RS05220 ENOG4105DDN Pentapeptide repeat-containing protein FOC92_RS05225 ENOG4105XDF Protein of unknown function (DUF1272) FOC92_RS05230 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) FOC92_RS05235 ENOG4105CMG Carbohydrate kinase FOC92_RS05240 ENOG4105C6Z Gluconate FOC92_RS05245 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC92_RS05255 ENOG4105CV1 Transketolase (EC 2.2.1.1) FOC92_RS05260 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase FOC92_RS05285 ENOG4105C8Q Methyl-accepting chemotaxis FOC92_RS05290 ENOG4108UX3 '-nucleotidase FOC92_RS05295 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC92_RS05300 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) FOC92_RS05305 ENOG4105KVH Transcriptional regulator FOC92_RS05330 ENOG4105C44 Serine transporter FOC92_RS05360 ENOG4108TZY GntR Family Transcriptional Regulator FOC92_RS05365 ENOG4105D9R oxidoreductase FOC92_RS05405 ENOG4105JAB phenazine biosynthesis protein, phzf family FOC92_RS05415 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein FOC92_RS05420 ENOG4105KVH Transcriptional regulator FOC92_RS05475 ENOG410829K Lysine exporter protein (Lyse ygga) FOC92_RS05495 ENOG4105KAF membrAne FOC92_RS05525 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) FOC92_RS05550 ENOG4105H3G oxidoreductase FOC92_RS05620 ENOG4108TN2 lmbE family FOC92_RS05630 ENOG4107R3E Citrate transporter FOC92_RS05640 ENOG4105WCN acetyltransferase FOC92_RS05645 ENOG4108MES Periplasmic binding protein FOC92_RS05650 ENOG4105EHG Permease protein FOC92_RS05655 ENOG4105DQ5 transport system permease protein FOC92_RS05680 ENOG41068WN FOC92_RS05685 ENOG4107CUJ Protein of unknown function (DUF2690) FOC92_RS05695 ENOG4107V2S Transcriptional regulator FOC92_RS05705 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC92_RS05720 ENOG4105C98 muts2 protein FOC92_RS05730 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase FOC92_RS05735 ENOG4105DPN Oligoendopeptidase f FOC92_RS05740 ENOG4108A04 Beta-lactamase FOC92_RS05765 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC92_RS05775 ENOG41082BM Transcriptional regulator, arsr family FOC92_RS05780 ENOG4105CIS alcohol dehydrogenase FOC92_RS05805 ENOG4105CQB FAD linked oxidase domain protein FOC92_RS05830 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC92_RS05835 ENOG4107TPS domain protein FOC92_RS05840 ENOG4105CEP NADH dehydrogenase FOC92_RS05850 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C FOC92_RS05855 ENOG4108M1A Chitin-binding protein FOC92_RS05865 ENOG4105E1K spore germination protein FOC92_RS05885 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase FOC92_RS05895 ENOG4108IAJ Nad-dependent epimerase dehydratase FOC92_RS05900 ENOG4105FAW cDP-glucose 4,6-dehydratase FOC92_RS05905 ENOG4105D7V transposase FOC92_RS05965 ENOG4105BZU Histidine kinase FOC92_RS05970 ENOG4105C5H ABC transporter FOC92_RS05980 ENOG4107DUR UPF0457 protein FOC92_RS06000 ENOG4105BZU Histidine kinase FOC92_RS06010 ENOG4105KT7 mgtC SapB transporter FOC92_RS06020 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC92_RS06025 ENOG41073R8 VanW family FOC92_RS06035 ENOG4108R1P FOC92_RS06050 ENOG4105VEQ Cold shock protein FOC92_RS06075 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) FOC92_RS06095 ENOG410904N short-chain dehydrogenase reductase FOC92_RS06105 ENOG4106IQC argininosuccinate lyase FOC92_RS06120 ENOG4108IA2 Sodium pantothenate symporter FOC92_RS06130 ENOG4105C26 Dehydrogenase FOC92_RS06135 ENOG4105CHR reductase FOC92_RS06145 ENOG4105EWU Squalene--hopene cyclase FOC92_RS06155 ENOG4105FR1 rard protein FOC92_RS06160 ENOG410696E Membrane FOC92_RS06175 ENOG4105D1F ATP-binding protein FOC92_RS06185 ENOG4108ZAF Molybdopterin FOC92_RS06190 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC92_RS06195 ENOG4105D06 uba thif-type nad fad binding protein FOC92_RS06200 ENOG4105TMB Formate nitrite transporter FOC92_RS06210 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC92_RS06215 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) FOC92_RS06225 ENOG4108JB9 formate dehydrogenase FOC92_RS06230 ENOG4105E1K spore germination protein FOC92_RS06245 ENOG4105CUB amino acid FOC92_RS06300 ENOG4108KGH TRANSCRIPTIONal FOC92_RS06310 ENOG4105EMN RNA polymerase sigma factor FOC92_RS06320 ENOG4105CIG ABC transporter FOC92_RS06340 ENOG4105D9R oxidoreductase FOC92_RS06350 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC92_RS06355 ENOG4105K4P CoA-binding domain protein FOC92_RS06360 ENOG4105C0H protease FOC92_RS06365 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS06375 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase FOC92_RS06385 ENOG4105W8X HesB YadR YfhF-family protein FOC92_RS06415 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC92_RS06420 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC92_RS06435 ENOG4105BZ1 (ABC) transporter FOC92_RS06440 ENOG4108I0Z Aconitate hydratase FOC92_RS06470 ENOG4105E5W Transporter FOC92_RS06480 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC92_RS06500 ENOG4107F3J Amp-dependent synthetase and ligase FOC92_RS06505 ENOG4107ZYJ bioY protein FOC92_RS06510 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS06515 ENOG4108IMY Transcriptional regulator FOC92_RS06540 ENOG4105D9G High-affinity FOC92_RS06545 ENOG4105IW1 AmiS UreI transporter FOC92_RS06560 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) FOC92_RS06600 ENOG4107AYK membrAne FOC92_RS06610 ENOG4105BZU Histidine kinase FOC92_RS06615 ENOG4105FBA Phospholipase Carboxylesterase FOC92_RS06620 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase FOC92_RS06630 ENOG4105CBC glutamate synthase FOC92_RS06635 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase FOC92_RS06640 ENOG4108VJ1 Transcriptional regulator (CarD family FOC92_RS06645 ENOG4108903 Formimidoylglutamase FOC92_RS06655 ENOG4105CGP Urocanate hydratase FOC92_RS06670 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) FOC92_RS06675 ENOG4108Z0Z intracellular protease Pfpi family FOC92_RS06700 ENOG4107QIV Cytochrome c biogenesis protein FOC92_RS06720 ENOG4105CJ1 ABC, transporter FOC92_RS06735 ENOG4107RSM transcriptional regulator FOC92_RS06745 ENOG41067MG lrgb family FOC92_RS06785 ENOG4105BZ1 (ABC) transporter FOC92_RS06790 ENOG4105BZ1 (ABC) transporter FOC92_RS06825 ENOG4108HW3 (ABC) transporter FOC92_RS06830 ENOG4105CGH 5'-nucleotidase FOC92_RS06840 ENOG4108SVB resolvase FOC92_RS06860 ENOG4105K7K Transcriptional regulator FOC92_RS06865 ENOG4105C5F glutamine synthetase FOC92_RS06870 ENOG4105KV4 Transcriptional regulator FOC92_RS06875 ENOG4105CXI aluminum resistance protein FOC92_RS06880 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC92_RS06885 ENOG4105EN6 Membrane FOC92_RS06895 ENOG4106F1P AAA ATPase, central domain protein FOC92_RS06925 ENOG41069ER domain protein FOC92_RS06930 ENOG4105DM4 PTS System FOC92_RS06935 ENOG4105DE4 1-phosphofructokinase FOC92_RS06940 ENOG4105E98 transcriptional regulator DeoR family FOC92_RS06945 ENOG4107QW4 alcohol dehydrogenase FOC92_RS06950 ENOG4108SJC Membrane FOC92_RS06960 ENOG4105C85 amino acid FOC92_RS06975 ENOG4105TMB Formate nitrite transporter FOC92_RS06980 ENOG4105K70 DNA-binding protein FOC92_RS06990 ENOG4105C59 p-type ATPase FOC92_RS06995 ENOG410681U heavy metal transport detoxification protein FOC92_RS07000 ENOG4105VPX protein, conserved in bacteria FOC92_RS07010 ENOG4105NIV Esterase FOC92_RS07015 ENOG4105E0A ABC, transporter FOC92_RS07045 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC92_RS07050 ENOG4105D03 DNA-3-methyladenine glycosylase II FOC92_RS07075 ENOG4105BZU Histidine kinase FOC92_RS07095 ENOG4105C5E polysaccharide biosynthesis protein FOC92_RS07115 ENOG41067MG lrgb family FOC92_RS07135 ENOG4108S3Y transcriptional regulator FOC92_RS07140 ENOG4105CS2 ec 3.2.1.21 FOC92_RS07145 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C FOC92_RS07155 ENOG4105F0V Cell wall hydrolase FOC92_RS07165 ENOG4105E0M Sulfatase FOC92_RS07170 ENOG410890F Dynamin family FOC92_RS07205 ENOG4105DQU oxidoreductase, subunit beta FOC92_RS07210 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein FOC92_RS07215 ENOG4108IGT Dipeptidase FOC92_RS07220 ENOG4105MCT stage V sporulation protein S FOC92_RS07225 ENOG4105D48 metallophosphoesterase FOC92_RS07255 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase FOC92_RS07270 ENOG4105XZV Protein of unknown function (DUF3243) FOC92_RS07275 ENOG4108RKS Short-chain dehydrogenase reductase Sdr FOC92_RS07295 ENOG4105UIB (ABC) transporter FOC92_RS07300 ENOG4108JQ9 ABC transporter FOC92_RS07305 ENOG4105DIH basic membrane FOC92_RS07310 ENOG4105FDP GntR family transcriptional regulator FOC92_RS07315 ENOG4105CNU cell division protein FtsK FOC92_RS07325 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit FOC92_RS07335 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC92_RS07345 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC92_RS07350 ENOG4108S0H Dipicolinic acid synthetase, b subunit FOC92_RS07355 ENOG4105E35 Dipicolinate synthase subunit A FOC92_RS07365 ENOG4105C1V Peptidase, M16 FOC92_RS07385 ENOG4105DTN riboflavin biosynthesis protein ribF FOC92_RS07400 ENOG4105W7A Protein of unknown function (DUF503) FOC92_RS07410 ENOG4105VHM ribosomal protein FOC92_RS07415 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination FOC92_RS07420 ENOG4105CHV Transcription elongation factor NusA FOC92_RS07430 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) FOC92_RS07440 ENOG4105DZP Membrane-associated zinc metalloprotease FOC92_RS07445 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) FOC92_RS07450 ENOG4105KNE Phosphatidate cytidylyltransferase FOC92_RS07455 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) FOC92_RS07465 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC92_RS07495 ENOG4108HE4 integrase family FOC92_RS07505 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) FOC92_RS07510 ENOG4105C79 DNA protecting protein DprA FOC92_RS07515 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha FOC92_RS07530 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) FOC92_RS07555 ENOG4105VB6 UPF0109 protein FOC92_RS07575 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) FOC92_RS07580 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) FOC92_RS07595 ENOG4105CHR reductase FOC92_RS07600 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase FOC92_RS07615 ENOG4105CB5 ATP-dependent DNA helicase recG FOC92_RS07620 ENOG4105DP4 dak2 domain fusion protein ylov FOC92_RS07625 ENOG4108ZAA Alkaline-shock protein FOC92_RS07640 ENOG4105FJ0 thiamine FOC92_RS07645 ENOG4105DJV ribulose-phosphate 3-epimerase FOC92_RS07650 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC92_RS07655 ENOG4105D9P serine threonine protein kinase FOC92_RS07660 ENOG4108ZF3 Phosphatase FOC92_RS07670 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B FOC92_RS07685 ENOG4105C25 Primosomal protein n' FOC92_RS07690 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase FOC92_RS07710 ENOG4105DSJ YicC domain protein FOC92_RS07730 ENOG4105DC7 peptidase M24 FOC92_RS07765 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) FOC92_RS07770 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain FOC92_RS07780 ENOG4105CD3 dihydroorotase FOC92_RS07800 ENOG4105C34 Pseudouridine synthase FOC92_RS07825 ENOG4105DBK s4 domain protein FOC92_RS07830 ENOG41067XK integral membrane protein FOC92_RS07840 ENOG4105DFA alanine racemase domain protein FOC92_RS07845 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase FOC92_RS07850 ENOG4105WR5 sporulation protein, YlmC YmxH family FOC92_RS07860 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS07870 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) FOC92_RS07875 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) FOC92_RS07885 ENOG4105D4A Cell wall formation (By similarity) FOC92_RS07890 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FOC92_RS07895 ENOG4105CNI cell division protein FtsW FOC92_RS07910 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) FOC92_RS07915 ENOG4105CJN penicillin-binding protein FOC92_RS07920 ENOG4105CJN penicillin-binding protein FOC92_RS07935 ENOG41074B2 UPF0747 protein FOC92_RS07960 ENOG4105KNH Nucleic acid-binding protein FOC92_RS07970 ENOG41063PX domain protein FOC92_RS07975 ENOG4105D78 K07001 NTE family protein FOC92_RS07980 ENOG4105H20 Sporulation integral membrane protein YlbJ FOC92_RS07990 ENOG4106H78 methyltransferase FOC92_RS08010 ENOG4107TB6 phosphoglycerate mutase FOC92_RS08025 ENOG4106UY4 Inherit from COG: Scp-like extracellular FOC92_RS08075 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) FOC92_RS08080 ENOG4105CNI cell division protein FtsW FOC92_RS08095 ENOG4108IAB Phoh family FOC92_RS08115 ENOG4105QA2 FOC92_RS08120 ENOG4105CI3 gtp-binding protein typa FOC92_RS08130 ENOG4105ECY inositol monophosphatase FOC92_RS08150 ENOG4105CXN decarboxylase FOC92_RS08200 ENOG4105CPP Dehydrogenase, E1 component FOC92_RS08215 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) FOC92_RS08220 ENOG4108X4Q Hydrolase FOC92_RS08230 ENOG4105CN5 Metallo-Beta-Lactamase FOC92_RS08235 ENOG4107ZYR domain protein FOC92_RS08270 ENOG4108XRC Protein of unknown function (DUF458) FOC92_RS08280 ENOG4107IN1 Protein of unknown function (DUF1797) FOC92_RS08295 ENOG4105EPM Diguanylate phosphodiesterase FOC92_RS08300 ENOG4105K6S Short-chain dehydrogenase reductase Sdr FOC92_RS08315 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) FOC92_RS08325 ENOG4105UIN FOC92_RS08360 ENOG4107QYE Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) FOC92_RS08380 ENOG4108HGU Histidine kinase FOC92_RS08390 ENOG4105CHM Aminotransferase FOC92_RS08395 ENOG4105FKQ transcriptional regulator FOC92_RS08400 ENOG4105EG2 ABC transporter, permease FOC92_RS08410 ENOG4107FKK extracellular solute-binding protein family 1 FOC92_RS08420 ENOG4105CG3 alpha amylase, catalytic region FOC92_RS08465 ENOG4105CHU acetyl-coa acetyltransferase FOC92_RS08495 ENOG4105K7K Transcriptional regulator FOC92_RS08500 ENOG4105DTD Dehydrogenase FOC92_RS08520 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase FOC92_RS08545 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) FOC92_RS08560 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC92_RS08570 ENOG4105BZU Histidine kinase FOC92_RS08590 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) FOC92_RS08605 ENOG4105CID antiterminator FOC92_RS08625 ENOG4105CE4 GlcNAc 6-P deacetylase FOC92_RS08660 ENOG4107ZE5 PPIases accelerate the folding of proteins FOC92_RS08665 ENOG4105PTM secreted protein FOC92_RS08670 ENOG4105J7I hydrolase FOC92_RS08680 ENOG4105G6R Stage v sporulation protein ae FOC92_RS08690 ENOG4105CZ3 stage V sporulation protein ad FOC92_RS08695 ENOG41090VF Stage v sporulation protein ac FOC92_RS08715 ENOG4105C8J )-transporter FOC92_RS08720 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS08730 ENOG41082AN stage II sporulation protein FOC92_RS08735 ENOG4105DZ1 carboxypeptidase FOC92_RS08740 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS08745 ENOG4105DVE abc transporter atp-binding protein FOC92_RS08775 ENOG4105D7N magnesium and cobalt transport protein CorA FOC92_RS08800 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) FOC92_RS08810 ENOG4105I3K Ferric uptake regulator, Fur family FOC92_RS08815 ENOG4105MZ9 stage II sporulation protein m FOC92_RS08835 ENOG4105CPC Aldo Keto reductase FOC92_RS08845 ENOG4105RHY Pfam:UPF0157 FOC92_RS08865 ENOG4107SKW Inherit from COG: Alpha beta hydrolase FOC92_RS08875 ENOG4105ETE Transcriptional regulator (LacI family FOC92_RS08880 ENOG4108YM7 Gcn5-related n-acetyltransferase FOC92_RS08900 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) FOC92_RS08905 ENOG4108R6K riboflavin synthase, subunit alpha FOC92_RS08930 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC92_RS08935 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC92_RS08950 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC92_RS08960 ENOG4105DFD Na H antiporter FOC92_RS08965 ENOG4105CGH 5'-nucleotidase FOC92_RS08990 ENOG4105DBV ornithine carbamoyltransferase FOC92_RS09005 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) FOC92_RS09020 ENOG4108IXY short-chain dehydrogenase reductase FOC92_RS09025 ENOG41069FQ Metallo-beta-lactamase superfamily FOC92_RS09030 ENOG4105II7 pyrroline-5-carboxylate reductase FOC92_RS09035 ENOG4105EJQ L-serine dehydratase FOC92_RS09050 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) FOC92_RS09065 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic FOC92_RS09080 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) FOC92_RS09085 ENOG4105D9U N-acetyltransferase FOC92_RS09100 ENOG4108VZI ErfK ybiS ycfS ynhG family protein FOC92_RS09105 ENOG4108QEG Membrane FOC92_RS09110 ENOG4105CDA abc transporter atp-binding protein FOC92_RS09115 ENOG4105E5Q amino acid AbC transporter FOC92_RS09120 ENOG4108HW3 (ABC) transporter FOC92_RS09130 ENOG4105G7B Protein of unknown function (DUF2992) FOC92_RS09140 ENOG4108QY0 Membrane FOC92_RS09150 ENOG4105C7S Dehydrogenase FOC92_RS09155 ENOG4105CPP Dehydrogenase, E1 component FOC92_RS09175 ENOG4107RDP Dehydrogenase FOC92_RS09185 ENOG4108JUB Transcriptional regulator FOC92_RS09195 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC92_RS09210 ENOG4107QQR Sporulation FOC92_RS09215 ENOG4105S1Z Stage IV sporulation protein B FOC92_RS09220 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) FOC92_RS09225 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) FOC92_RS09230 ENOG4105DX0 Hemolysin A FOC92_RS09240 ENOG4105CTB Polyprenyl synthetase FOC92_RS09255 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) FOC92_RS09265 ENOG4108ZSR alkaline shock protein FOC92_RS09270 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC92_RS09295 ENOG410644B Stage III sporulation protein af FOC92_RS09305 ENOG4105KQ4 Stage iii sporulation protein ad FOC92_RS09310 ENOG4108CQH stage III sporulation protein AC FOC92_RS09315 ENOG4105KR5 Stage iii sporulation protein FOC92_RS09320 ENOG4105CD2 stage iii sporulation protein aa FOC92_RS09345 ENOG4105DC7 peptidase M24 FOC92_RS09350 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) FOC92_RS09360 ENOG4105CBJ Metal-dependent enzyme FOC92_RS09370 ENOG4107YBY Hydrolase FOC92_RS09400 ENOG41082GG biotin lipoate A B protein ligase FOC92_RS09405 ENOG4105WZW rhodanese family FOC92_RS09430 ENOG41080TC multidrug resistance protein FOC92_RS09460 ENOG4105CJ1 ABC, transporter FOC92_RS09465 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS09495 ENOG4105C0D helicase FOC92_RS09615 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) FOC92_RS09620 ENOG4105C3R Methionine synthase FOC92_RS09630 ENOG4105C28 cystathionine FOC92_RS09635 ENOG4105C28 cystathionine FOC92_RS09655 ENOG4105C5X domain protein FOC92_RS09665 ENOG4105DKQ ROK family FOC92_RS09675 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase FOC92_RS09690 ENOG4108UTW Plays a role in the regulation of phosphate uptake FOC92_RS09695 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS09700 ENOG4105C8U phosphate abc transporter FOC92_RS09705 ENOG4105C8U phosphate abc transporter FOC92_RS09715 ENOG4107RF6 penicillin-binding protein FOC92_RS09725 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC92_RS09750 ENOG4105N80 Ferric uptake regulator, Fur family FOC92_RS09760 ENOG4105FDK ABC transporter FOC92_RS09765 ENOG4108JYZ YitT family FOC92_RS09770 ENOG41069ZM Protein of unknown function (DUF2624) FOC92_RS09795 ENOG4105EGD dinuclear metal center protein, YbgI family FOC92_RS09810 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS09815 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) FOC92_RS09845 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) FOC92_RS09850 ENOG4105KG3 cytidine deaminase FOC92_RS09855 ENOG4107YR5 Diacylglycerol kinase FOC92_RS09865 ENOG4105CTJ Metal Dependent Phosphohydrolase FOC92_RS09870 ENOG4105C9A Phoh family FOC92_RS09880 ENOG41068P3 sporulation protein YqfC FOC92_RS09885 ENOG4105KTH gatB Yqey FOC92_RS09895 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) FOC92_RS09900 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) FOC92_RS09930 ENOG4105CSA Coproporphyrinogen iii oxidase FOC92_RS09935 ENOG4105KVH Transcriptional regulator FOC92_RS09960 ENOG4105TQK DNA polymerase iii, delta' subunit FOC92_RS09970 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 FOC92_RS09975 ENOG4108UK2 deaminase FOC92_RS09980 ENOG4105KQC Competence protein FOC92_RS09990 ENOG4105DXX methyltransferase FOC92_RS10000 ENOG4108WF2 Metal Dependent Phosphohydrolase FOC92_RS10010 ENOG410812S Rna-binding protein FOC92_RS10020 ENOG4105CQW ribosome biogenesis GTPase YqeH FOC92_RS10025 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase FOC92_RS10040 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS10060 ENOG4108TVJ Nitroreductase FOC92_RS10075 ENOG4105G6Z alkaline phosphatase FOC92_RS10080 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FOC92_RS10085 ENOG4108MUZ hydrolase FOC92_RS10115 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC92_RS10120 ENOG4105MIR Phenylalanine 4-monooxygenase FOC92_RS10130 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase FOC92_RS10170 ENOG4105S6R Iron-hydroxamate transporter permease subunit FOC92_RS10175 ENOG4108V5C ABC transporter FOC92_RS10185 ENOG4105C0A alcohol dehydrogenase FOC92_RS10190 ENOG4105C28 cystathionine FOC92_RS10220 ENOG4107XRG penicillin-binding protein FOC92_RS10230 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) FOC92_RS10240 ENOG4105CFP Peptidase U32 FOC92_RS10245 ENOG4105XYU peptidase (U32 family) FOC92_RS10255 ENOG4105HHA aminodeoxychorismate lyase FOC92_RS10275 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC92_RS10285 ENOG4105C02 permease FOC92_RS10300 ENOG41060CR FOC92_RS10305 ENOG4105C7H Helicase, RecD TraA family FOC92_RS10315 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) FOC92_RS10320 ENOG4105C3J Cysteine desulfurase FOC92_RS10330 ENOG4105D1H recombination factor protein RarA FOC92_RS10335 ENOG4108VCI transcription factor, rsfa family FOC92_RS10340 ENOG4105CUZ uba thif-type nad fad binding protein FOC92_RS10350 ENOG4105CUT histidyl-tRNA synthetase FOC92_RS10360 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) FOC92_RS10365 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) FOC92_RS10375 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) FOC92_RS10380 ENOG41076HS cation diffusion facilitator family transporter FOC92_RS10385 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) FOC92_RS10395 ENOG4105CKP Polysaccharide Biosynthesis Protein FOC92_RS10400 ENOG4108QG2 Membrane FOC92_RS10410 ENOG4105VIE preprotein translocase, subunit YajC FOC92_RS10425 ENOG41061AI Protein of unknown function (DUF2905) FOC92_RS10440 ENOG4108HUF Transporter FOC92_RS10470 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) FOC92_RS10475 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase FOC92_RS10480 ENOG4108IYU L-aspartate oxidase FOC92_RS10495 ENOG4108RPX mosc domain containing protein FOC92_RS10500 ENOG4105CQC Prephenate dehydratase FOC92_RS10515 ENOG4105C19 ABC transporter FOC92_RS10520 ENOG4105EWM Histidine kinase FOC92_RS10530 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control FOC92_RS10545 ENOG4105X36 (ribosomal) protein FOC92_RS10555 ENOG4105C03 ribonuclease FOC92_RS10570 ENOG4107QMS site-determining protein FOC92_RS10590 ENOG4105DFF Rod shape-determining protein mreb FOC92_RS10610 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase FOC92_RS10615 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) FOC92_RS10625 ENOG41068KH stage VI sporulation protein D FOC92_RS10635 ENOG4105D52 delta-aminolevulinic acid dehydratase FOC92_RS10660 ENOG4105K56 Transcriptional regulator FOC92_RS10680 ENOG4108IUQ atp-dependent protease FOC92_RS10705 ENOG4108QCI YvbH-like oligomerisation region FOC92_RS10725 ENOG4105M59 Phosphodiesterase, mj0936 family FOC92_RS10740 ENOG4108XJQ germination protein FOC92_RS10755 ENOG4105PFC Transcriptional regulator FOC92_RS10765 ENOG4105DZC cytosine deaminase FOC92_RS10770 ENOG41067S9 phage shock protein C, PspC FOC92_RS10775 ENOG4108JCI Transcriptional regulator FOC92_RS10785 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) FOC92_RS10790 ENOG4108Z40 Transcriptional regulator FOC92_RS10795 ENOG4105RHA ABC transporter, permease FOC92_RS10800 ENOG4108IUX (ABC) transporter FOC92_RS10805 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family FOC92_RS10810 ENOG4105ER2 Ompa motb domain protein FOC92_RS10815 ENOG4105E14 MotA TolQ exbB proton channel FOC92_RS10820 ENOG4108VXD carboxy-peptidase FOC92_RS10830 ENOG4105E33 succinate dehydrogenase FOC92_RS10840 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit FOC92_RS10850 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) FOC92_RS10855 ENOG4105K63 Thioredoxin FOC92_RS10860 ENOG4105C10 Electron transfer flavoprotein FOC92_RS10865 ENOG4105BZJ Electron transfer flavoprotein FOC92_RS10870 ENOG41060WC Enoyl-CoA hydratase FOC92_RS10875 ENOG4107Z3H Transcriptional regulator, TetR family FOC92_RS10880 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS10945 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS10960 ENOG4105DR4 Methyltransferase FOC92_RS10970 ENOG4105KFN sortase, SrtB family FOC92_RS10975 ENOG4105E0A ABC, transporter FOC92_RS10990 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) FOC92_RS11000 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) FOC92_RS11010 ENOG4105FE9 pseudouridine synthase FOC92_RS11020 ENOG4105DCG PHP domain protein FOC92_RS11035 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) FOC92_RS11055 ENOG4105C5S asparaginyl-tRNA synthetase FOC92_RS11060 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) FOC92_RS11070 ENOG4108RWN rrna methyltransferase FOC92_RS11100 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS11105 ENOG4105CW7 secretion protein, HlyD family FOC92_RS11110 ENOG4108JGH Tetr family transcriptional regulator FOC92_RS11115 ENOG4105CN9 Peptidase m42 family protein FOC92_RS11135 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) FOC92_RS11140 ENOG4105C22 threonyL-tRNA synthetase FOC92_RS11145 ENOG4108TDW sporulation protein YtxC FOC92_RS11175 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase FOC92_RS11180 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) FOC92_RS11190 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) FOC92_RS11195 ENOG4105C2M dna polymerase I FOC92_RS11200 ENOG4105BZU Histidine kinase FOC92_RS11205 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS11225 ENOG4108HMX isocitrate dehydrogenase (NADP) FOC92_RS11230 ENOG4105BZN citrate synthase FOC92_RS11240 ENOG4108REF Sporulation integral membrane protein ytvi FOC92_RS11245 ENOG4105FS0 cytoplasmic membrane protein FOC92_RS11270 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS11275 ENOG4105C6K Malic enzyme FOC92_RS11280 ENOG4105C0B DNA polymerase III (alpha subunit) FOC92_RS11285 ENOG4105VV2 FOC92_RS11295 ENOG4105SFS phosphoesterase RecJ domain protein FOC92_RS11320 ENOG4105E8R UPF0173 metal-dependent hydrolase FOC92_RS11325 ENOG4105DC7 peptidase M24 FOC92_RS11365 ENOG41082W1 Cupin 2, conserved barrel domain protein FOC92_RS11385 ENOG4107YZX Universal stress protein FOC92_RS11420 ENOG4108JYZ YitT family FOC92_RS11440 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) FOC92_RS11450 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) FOC92_RS11455 ENOG4105KBJ sporulation protein ytfj FOC92_RS11470 ENOG4105EFZ amidohydrolase FOC92_RS11480 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC92_RS11505 ENOG4105RQF LysR family Transcriptional regulator FOC92_RS11515 ENOG4105U5Y Transcriptional regulator FOC92_RS11525 ENOG4105C28 cystathionine FOC92_RS11680 ENOG4105EMN RNA polymerase sigma factor FOC92_RS11690 ENOG4108UW5 maltose o-acetyltransferase FOC92_RS11700 ENOG4105F1V Acetoin utilization protein FOC92_RS11705 ENOG4105W87 Cbs domain FOC92_RS11710 ENOG4105DGU Histone deacetylase FOC92_RS11725 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS11730 ENOG4105BZU Histidine kinase FOC92_RS11735 ENOG4107SNB ankyrin repeat protein YahD FOC92_RS11740 ENOG4105EP9 oxidoreductase FOC92_RS11760 ENOG4105ETE Transcriptional regulator (LacI family FOC92_RS11765 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC92_RS11785 ENOG4105C88 aminopeptidase FOC92_RS11820 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase FOC92_RS11830 ENOG4108VDD TRNA binding domain protein FOC92_RS11860 ENOG4105C8F Beta-lactamase domain protein FOC92_RS11875 ENOG4108V15 phosphotransferase enzyme family FOC92_RS11880 ENOG4108IUM Glycogen debranching enzyme FOC92_RS11890 ENOG4107QSE Dipeptidase FOC92_RS11895 ENOG4105YW5 deoR family transcriptional regulator FOC92_RS11910 ENOG4105CBX hi0933 family FOC92_RS11945 ENOG4108VJ1 Transcriptional regulator (CarD family FOC92_RS11950 ENOG4107EXU Short-chain dehydrogenase reductase Sdr FOC92_RS11955 ENOG4105CSC Glucose uptake protein FOC92_RS11970 ENOG4108ZAF Molybdopterin FOC92_RS11975 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein FOC92_RS11980 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC92_RS11990 ENOG4105D06 uba thif-type nad fad binding protein FOC92_RS11995 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC92_RS12015 ENOG41085GJ domain protein FOC92_RS12025 ENOG4105DWV Homoserine O-trans-acetylase FOC92_RS12035 ENOG4108B31 Spore germination protein FOC92_RS12065 ENOG4105C8T Leucyl-tRNA synthetase FOC92_RS12070 ENOG410605W Major Facilitator FOC92_RS12075 ENOG4107S91 Sodium hydrogen exchanger FOC92_RS12080 ENOG4105NCW Trka-c domain protein FOC92_RS12095 ENOG4105C19 ABC transporter FOC92_RS12115 ENOG4105N5T Radical SAM Protein FOC92_RS12125 ENOG4105DA5 (ABC) transporter FOC92_RS12150 ENOG4105E8V Alpha Beta Hydrolase Fold protein FOC92_RS12155 ENOG4108Z0R Transferase FOC92_RS12160 ENOG4105YVM Phosphoesterase, PA-phosphatase related FOC92_RS12165 ENOG4105BZF Glycosyl transferase (Group 1 FOC92_RS12175 ENOG4105EPU Molybdenum cofactor synthesis domain protein FOC92_RS12185 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC92_RS12225 ENOG4105BZU Histidine kinase FOC92_RS12230 ENOG4105BZU Histidine kinase FOC92_RS12235 ENOG4107S9D Alpha beta hydrolase FOC92_RS12240 ENOG4107T7U Sulfatase FOC92_RS12265 ENOG4105D2X ABC transporter substrate-binding protein FOC92_RS12275 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component FOC92_RS12340 ENOG4108V2W Carbonate dehydratase FOC92_RS12345 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC92_RS12350 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC92_RS12385 ENOG41087YS Phage shock protein A FOC92_RS12415 ENOG4105BZU Histidine kinase FOC92_RS12420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS12445 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC92_RS12450 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) FOC92_RS12480 ENOG4107ZTW SNARE associated Golgi FOC92_RS12495 ENOG4105C19 ABC transporter FOC92_RS12500 ENOG41086D8 Transcriptional regulator FOC92_RS12520 ENOG41082BM Transcriptional regulator, arsr family FOC92_RS12570 ENOG4105C6Z Gluconate FOC92_RS12595 ENOG41069H0 dihydroorotase EC 3.5.2.3 FOC92_RS12615 ENOG4105DTQ mandelate racemase muconate lactonizing FOC92_RS12625 ENOG4108IPT Naphthoate synthase FOC92_RS12630 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) FOC92_RS12640 ENOG4105E4F Isochorismate synthase FOC92_RS12645 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase FOC92_RS12655 ENOG4105VEQ Cold shock protein FOC92_RS12690 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) FOC92_RS12805 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation FOC92_RS12840 ENOG4105KT7 mgtC SapB transporter FOC92_RS12845 ENOG4107PBV potassium channel FOC92_RS12860 ENOG4105WG9 Conserved Protein FOC92_RS12870 ENOG4105CHM Aminotransferase FOC92_RS12875 ENOG4108ZB6 transcriptional regulator AsnC family FOC92_RS12880 ENOG4105C5I Dehydrogenase FOC92_RS12885 ENOG4108MUZ hydrolase FOC92_RS12895 ENOG4105C87 Aminotransferase class I and II FOC92_RS12910 ENOG4105Y38 Kinase-associated protein B FOC92_RS12920 ENOG4107R3E Citrate transporter FOC92_RS12940 ENOG4105KA0 thioesterase Superfamily protein FOC92_RS12955 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC92_RS12975 ENOG41069ER domain protein FOC92_RS12990 ENOG4105CEP NADH dehydrogenase FOC92_RS13020 ENOG4105EWC Purine nucleoside phosphorylase FOC92_RS13035 ENOG4108YX9 iron--sulfur cluster insertion protein erpA FOC92_RS13060 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS13065 ENOG4105C4B ABC transporter, permease FOC92_RS13070 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA FOC92_RS13105 ENOG41083MR nifu domain-containing protein FOC92_RS13120 ENOG4108W5N phosphatidylglycerophosphatase a FOC92_RS13140 ENOG4105DAX Pfam:DUF2983 FOC92_RS13150 ENOG4105DYS nad(p)h dehydrogenase (quinone) FOC92_RS13155 ENOG4105D4U had-superfamily hydrolase, subfamily iia FOC92_RS13170 ENOG4105CBT Fructose-1,6-bisphosphatase FOC92_RS13185 ENOG4105MMD transcriptional regulator FOC92_RS13190 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FOC92_RS13195 ENOG4107TXC Transcriptional regulator FOC92_RS13200 ENOG41090T1 Membrane FOC92_RS13225 ENOG4105FAA peptidase M23 FOC92_RS13230 ENOG4108YTE sporulation protein YunB FOC92_RS13235 ENOG4105KZD Domain of unknown function (DUF1805) FOC92_RS13240 ENOG4107R8B 5'-nucleotidase FOC92_RS13245 ENOG4105DIW FeS assembly protein SUFB FOC92_RS13250 ENOG4108UNV SUF system FeS assembly protein, NifU family FOC92_RS13255 ENOG4105C9B Cysteine desulfurase FOC92_RS13260 ENOG4105JRK feS assembly protein SufD FOC92_RS13265 ENOG4105C3K feS assembly ATPase SufC FOC92_RS13270 ENOG4105D01 (LipO)protein FOC92_RS13275 ENOG4105D01 (LipO)protein FOC92_RS13280 ENOG4108UMI ABC transporter, permease FOC92_RS13285 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS13310 ENOG41080E8 Transcriptional regulator, Spx MgsR family FOC92_RS13330 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FOC92_RS13355 ENOG4108W8B Beta-lactamase domain protein FOC92_RS13360 ENOG4105C1G acyl-Coa dehydrogenase FOC92_RS13365 ENOG4105CHU acetyl-coa acetyltransferase FOC92_RS13380 ENOG4105DZ1 carboxypeptidase FOC92_RS13400 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC92_RS13415 ENOG4108SUT Major Facilitator Superfamily FOC92_RS13420 ENOG4107R7I amino acid FOC92_RS13435 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC92_RS13445 ENOG4107AYK membrAne FOC92_RS13480 ENOG4107ZTW SNARE associated Golgi FOC92_RS13490 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC92_RS13495 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS13500 ENOG4105BZU Histidine kinase FOC92_RS13515 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FOC92_RS13530 ENOG4105C8Q Methyl-accepting chemotaxis FOC92_RS13535 ENOG4105VG1 fes assembly suf system protein FOC92_RS13540 ENOG4105D4Y metalloprotease FOC92_RS13565 ENOG4107T5V SNARE associated Golgi FOC92_RS13570 ENOG4107S91 Sodium hydrogen exchanger FOC92_RS13575 ENOG4105NCW Trka-c domain protein FOC92_RS13585 ENOG4108RMU ferritin dps family protein FOC92_RS13600 ENOG4108URH decarboxylase FOC92_RS13610 ENOG41090A1 ferritin FOC92_RS13615 ENOG4105DHF Membrane FOC92_RS13620 ENOG4105D9N nucleoside FOC92_RS13625 ENOG4105D9N nucleoside FOC92_RS13640 ENOG4108RYK Nad-dependent epimerase dehydratase FOC92_RS13655 ENOG4105CV8 reductase FOC92_RS13660 ENOG4105F27 Major Facilitator FOC92_RS13665 ENOG4105KVH Transcriptional regulator FOC92_RS13680 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) FOC92_RS13685 ENOG4105D4A Cell wall formation (By similarity) FOC92_RS13695 ENOG4105C8Q Methyl-accepting chemotaxis FOC92_RS13705 ENOG4105WMR Protein CrcB homolog FOC92_RS13710 ENOG4105WMR Protein CrcB homolog FOC92_RS13730 ENOG4105C5H ABC transporter FOC92_RS13735 ENOG4108MK9 spermidine N(1)-acetyltransferase FOC92_RS13760 ENOG4108V2W Carbonate dehydratase FOC92_RS13765 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) FOC92_RS13780 ENOG4108IPW abc transporter atp-binding protein FOC92_RS13785 ENOG4105CM4 permease protein FOC92_RS13800 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS13840 ENOG4107RBB ABC transporter, permease FOC92_RS13845 ENOG4105C19 ABC transporter FOC92_RS13895 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) FOC92_RS13905 ENOG4105XZU Preprotein translocase, subunit SecG FOC92_RS13910 ENOG41067MG lrgb family FOC92_RS13960 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS13980 ENOG41090VF Stage v sporulation protein ac FOC92_RS13985 ENOG4105CZ3 stage V sporulation protein ad FOC92_RS14000 ENOG4108QY0 Membrane FOC92_RS14010 ENOG4105KRI phosphocarrier protein (HPr FOC92_RS14020 ENOG4105CHW UPF0052 protein FOC92_RS14030 ENOG4108Z4K mutator MutT protein FOC92_RS14040 ENOG4105C3M thioredoxin reductase FOC92_RS14050 ENOG4108S4C acetyltransferase FOC92_RS14070 ENOG41086DT Membrane protein of unknown function FOC92_RS14080 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC92_RS14085 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) FOC92_RS14100 ENOG4107TXC Transcriptional regulator FOC92_RS14120 ENOG4105DUM transcriptional regulator, lysR family FOC92_RS14130 ENOG4108WS4 fmn reductase FOC92_RS14145 ENOG4105BZ1 (ABC) transporter FOC92_RS14155 ENOG4105CN1 protease FOC92_RS14160 ENOG4105CRP Part of the ABC transporter FtsEX involved in FOC92_RS14165 ENOG4105CAK Cell division ATP-binding protein ftsE FOC92_RS14190 ENOG4108RDQ ABC transporter FOC92_RS14220 ENOG4105MS2 ribosomal subunit Interface protein FOC92_RS14225 ENOG4105VEQ Cold shock protein FOC92_RS14230 ENOG41081UC Inherit from COG: Competence protein FOC92_RS14245 ENOG4105KVH Transcriptional regulator FOC92_RS14255 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein FOC92_RS14260 ENOG4108KGH TRANSCRIPTIONal FOC92_RS14265 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase FOC92_RS14275 ENOG4105ESV Glycosyl transferase, family 4 FOC92_RS14285 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family FOC92_RS14305 ENOG4105F8D glycoside hydrolase family 4 FOC92_RS14310 ENOG4105VCP PTS System FOC92_RS14315 ENOG4105CK1 PTS System FOC92_RS14325 ENOG4105VCP PTS System FOC92_RS14335 ENOG4105VZJ PTS System FOC92_RS14355 ENOG4105ECB domain protein FOC92_RS14360 ENOG4107RSM transcriptional regulator FOC92_RS14395 ENOG4105DAA L-lactate FOC92_RS14405 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) FOC92_RS14415 ENOG4105E0M Sulfatase FOC92_RS14440 ENOG4107R8N Glycosyl transferase, family 2 FOC92_RS14445 ENOG4105C94 Transporter FOC92_RS14450 ENOG41069ER domain protein FOC92_RS14475 ENOG4105KBK Zinc finger, swim domain protein FOC92_RS14480 ENOG4105C0D helicase FOC92_RS14510 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS14520 ENOG4107RBB ABC transporter, permease FOC92_RS14525 ENOG4105C19 ABC transporter FOC92_RS14545 ENOG4105CXY transporter FOC92_RS14560 ENOG4105BZU Histidine kinase FOC92_RS14565 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS14575 ENOG4108KGH TRANSCRIPTIONal FOC92_RS14580 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC92_RS14590 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC92_RS14595 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC92_RS14605 ENOG4105CPK Glycosyl transferase (Group 1 FOC92_RS14610 ENOG4107EF8 Glycosyl transferase (Group 1 FOC92_RS14645 ENOG4107U9V N5-(Carboxyethyl)ornithine synthase FOC92_RS14655 ENOG4108PTS heparinase ii FOC92_RS14665 ENOG4105D3Q Sugar transferase FOC92_RS14670 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase FOC92_RS14675 ENOG4108RB3 Capsular polysaccharide biosynthesis protein FOC92_RS14680 ENOG4107YJ4 chain length determinant protein FOC92_RS14685 ENOG4105HTX biosynthesis protein FOC92_RS14690 ENOG4107YJ4 chain length determinant protein FOC92_RS14705 ENOG4105MT0 Sporulation transcriptional regulator spoiiid FOC92_RS14715 ENOG4105FRN stage II sporulation protein FOC92_RS14730 ENOG4105DY9 regulatoR FOC92_RS14750 ENOG4106778 Protein of unknown function (DUF1146) FOC92_RS14755 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC92_RS14760 ENOG4105C8S subunit m FOC92_RS14765 ENOG4105D65 subunit l FOC92_RS14790 ENOG4105CQV NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) FOC92_RS14795 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC92_RS14805 ENOG4105KWU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain FOC92_RS14810 ENOG4105BZU Histidine kinase FOC92_RS14860 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) FOC92_RS14865 ENOG41062M3 atp synthase FOC92_RS14885 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) FOC92_RS14890 ENOG4108UIC UPF0340 protein FOC92_RS14895 ENOG4108YZG isomerase FOC92_RS14910 ENOG4108VGI doxx family FOC92_RS14915 ENOG4107XC4 flavin reductase domain protein, FMN-binding FOC92_RS14930 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC92_RS14940 ENOG4108ZXQ stage ii sporulation protein r FOC92_RS14945 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) FOC92_RS14950 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) FOC92_RS14955 ENOG4107104 thymidine kinase FOC92_RS14965 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) FOC92_RS14970 ENOG4105CBT Fructose-1,6-bisphosphatase FOC92_RS14975 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) FOC92_RS14995 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) FOC92_RS15010 ENOG4105C1G acyl-Coa dehydrogenase FOC92_RS15015 ENOG4105C1G acyl-Coa dehydrogenase FOC92_RS15020 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase FOC92_RS15030 ENOG4105DF6 Fe-S oxidoreductase FOC92_RS15045 ENOG4105BZU Histidine kinase FOC92_RS15060 ENOG4105D4Y metalloprotease FOC92_RS15070 ENOG4105BZU Histidine kinase FOC92_RS15075 ENOG4105KCT ABC transporter FOC92_RS15080 ENOG4108M15 ABC transporter FOC92_RS15085 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) FOC92_RS15095 ENOG4105IIU Aminopeptidase FOC92_RS15115 ENOG4105JVQ RNA Polymerase FOC92_RS15125 ENOG410684U Domain of unknown function (DUF1934) FOC92_RS15145 ENOG4105CYW agmatinase FOC92_RS15155 ENOG4105DXB Major Facilitator superfamily FOC92_RS15160 ENOG4107SWG transcriptional regulator MERR family FOC92_RS15165 ENOG4108QXE glycerophosphoryl diester phosphodiesterase FOC92_RS15170 ENOG4105BZ4 penicillin-binding protein FOC92_RS15175 ENOG4108XFG YwhD family FOC92_RS15180 ENOG4108Z4T Peptidase M50 FOC92_RS15185 ENOG41069HH 4-oxalocrotonate tautomerase FOC92_RS15190 ENOG4105DCI Phosphohydrolase FOC92_RS15195 ENOG4108MES Periplasmic binding protein FOC92_RS15200 ENOG4105E0A ABC, transporter FOC92_RS15205 ENOG4105EHG Permease protein FOC92_RS15210 ENOG4105DQ5 transport system permease protein FOC92_RS15220 ENOG4108VCI transcription factor, rsfa family FOC92_RS15225 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) FOC92_RS15230 ENOG4108IJ2 phosphate acetyltransferase FOC92_RS15245 ENOG4108VKI Cell wall hydrolase FOC92_RS15265 ENOG4107SVH Potassium channel protein FOC92_RS15275 ENOG410667J hydrolase FOC92_RS15280 ENOG4105VCH membrane FOC92_RS15290 ENOG4108TU7 Inherit from COG: (ABC) transporter FOC92_RS15295 ENOG4105CJ1 ABC, transporter FOC92_RS15300 ENOG41090WU lipolytic protein G-D-S-L family FOC92_RS15315 ENOG4105D6E homoserine dehydrogenase FOC92_RS15340 ENOG4108Y4K DNA-binding transcriptional activator FOC92_RS15350 ENOG4105WH1 Two component transcriptional regulator luxr family FOC92_RS15355 ENOG4105BZU Histidine kinase FOC92_RS15360 ENOG4105DWF phosphomethylpyrimidine kinase FOC92_RS15365 ENOG4105BZU Histidine kinase FOC92_RS15370 ENOG4105VCD cytoplasmic protein FOC92_RS15375 ENOG4105D22 carbon starvation protein FOC92_RS15380 ENOG4105DY9 regulatoR FOC92_RS15385 ENOG41079KZ Major Facilitator Superfamily FOC92_RS15395 ENOG4105CG5 Glycosyl transferase (Group 1 FOC92_RS15405 ENOG4105EN6 Membrane FOC92_RS15410 ENOG4106YBV Methyl-accepting chemotaxis FOC92_RS15420 ENOG4108S4H thioesterase Superfamily protein FOC92_RS15425 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) FOC92_RS15440 ENOG4105K64 Glycosyl transferase, family 2 FOC92_RS15450 ENOG4105EJV Membrane FOC92_RS15455 ENOG4105CKK Glycosyl transferase, family 2 FOC92_RS15460 ENOG4105C5H ABC transporter FOC92_RS15465 ENOG41067SE Tetr family transcriptional regulator FOC92_RS15475 ENOG4105E0X reductase FOC92_RS15480 ENOG4106F5Q Membrane FOC92_RS15495 ENOG4108NEV two component transcriptional regulator, LytTR family FOC92_RS15500 ENOG4108HRK Histidine kinase FOC92_RS15505 ENOG4107RGD Major Facilitator superfamily FOC92_RS15520 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC92_RS15530 ENOG4105IW1 AmiS UreI transporter FOC92_RS15535 ENOG4105CMR udp-glucose 4-epimerase FOC92_RS15540 ENOG4108UT2 hemolysin iii FOC92_RS15550 ENOG4105C1J atp-dependent rna helicase FOC92_RS15555 ENOG4107SJ1 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity) FOC92_RS15575 ENOG4105BZU Histidine kinase FOC92_RS15590 ENOG4105C0H protease FOC92_RS15595 ENOG4105Q2H domain protein FOC92_RS15610 ENOG4105BZU Histidine kinase FOC92_RS15615 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS15640 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis FOC92_RS15645 ENOG4105CDU Replicative dna helicase FOC92_RS15655 ENOG4105BZR domain protein FOC92_RS15660 ENOG4108XMW Membrane FOC92_RS15670 ENOG4108UUM single-stranded DNA-binding protein FOC92_RS15680 ENOG4105C3G gtp-binding protein FOC92_RS15685 ENOG4105VDK protein, conserved in bacteria FOC92_RS15690 ENOG4105D8X mechanosensitive ion channel FOC92_RS15695 ENOG4108ZDA Sporulation protein YyaC FOC92_RS15700 ENOG4105FA0 parb-like partition protein FOC92_RS15705 ENOG4107QJE Chromosome Partitioning Protein FOC92_RS15725 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) FOC92_RS15735 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins FOC92_RS15755 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC92_RS15760 ENOG410848D S4 domain protein YaaA FOC92_RS15775 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) FOC92_RS15810 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) FOC92_RS15845 ENOG4105ZMH deoxynucleoside kinase FOC92_RS15855 ENOG4105GTG Isochorismatase FOC92_RS15860 ENOG4108Z6B deaminase FOC92_RS15870 ENOG4105C6E dna polymerase iii FOC92_RS15890 ENOG41067KS pro-sigma K processing FOC92_RS15925 ENOG4105CXN decarboxylase FOC92_RS15935 ENOG4105FA2 dna polymerase iii FOC92_RS15940 ENOG4105MA4 psp1 domain protein FOC92_RS15950 ENOG41060K3 Methyltransferase FOC92_RS15960 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) FOC92_RS15965 ENOG4105KRN Transcriptional regulator, abrb family FOC92_RS15970 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) FOC92_RS15975 ENOG4105F8V Hydrolase, tatD family FOC92_RS15980 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) FOC92_RS15990 ENOG4105XFA sporulation peptidase YabG FOC92_RS15995 ENOG4105W42 Veg protein FOC92_RS16010 ENOG4105DFT pur operon repressor FOC92_RS16015 ENOG4105KME endoribonuclease L-psp FOC92_RS16035 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) FOC92_RS16045 ENOG4108JA2 transcriptioN-repair coupling factor FOC92_RS16050 ENOG4108M14 stage v sporulation protein t FOC92_RS16060 ENOG4108IY2 MazG family FOC92_RS16065 ENOG41082I2 s4 domain protein FOC92_RS16070 ENOG4105VYY sporulation protein yabp FOC92_RS16085 ENOG41060GV RNA binding s1 domain protein FOC92_RS16105 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) FOC92_RS16110 ENOG4108UGV hypoxanthine phosphoribosyltransferase FOC92_RS16115 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) FOC92_RS16130 ENOG4105C6T cysteine synthase FOC92_RS16135 ENOG4105CRQ synthase (Component I) FOC92_RS16140 ENOG4105DDQ anthranilate synthase FOC92_RS16145 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 FOC92_RS16150 ENOG4105EEI dihydropteroate synthase FOC92_RS16155 ENOG4105KRF dihydroneopterin aldolase FOC92_RS16160 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FOC92_RS16170 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) FOC92_RS16260 ENOG4108Z0C Uvrb UvrC protein FOC92_RS16275 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) FOC92_RS16285 ENOG4105CTP PilT protein domain protein FOC92_RS16290 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) FOC92_RS16305 ENOG4105D7W serine acetyltransferase FOC92_RS16320 ENOG4105C2N RNA methyltransferase TrmH family group 3 FOC92_RS16325 ENOG4105M0M Tetracycline resistance protein FOC92_RS16330 ENOG4105QIV RNA polymerase FOC92_RS16345 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) FOC92_RS16370 ENOG4107Y49 methyltransferase FOC92_RS16385 ENOG4105XPM ribosomal protein FOC92_RS16515 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC92_RS16525 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC92_RS16560 ENOG4108JJB ABC transporter FOC92_RS16565 ENOG4108JJB ABC transporter FOC92_RS16570 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) FOC92_RS16575 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FOC92_RS16600 ENOG4105D1F ATP-binding protein FOC92_RS16615 ENOG4108NMV polysaccharide deacetylase FOC92_RS16695 ENOG4105C8B TIGR00159 family FOC92_RS16700 ENOG4107U5W ybbr family FOC92_RS16715 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) FOC92_RS16740 ENOG4108PSK reductase FOC92_RS16745 ENOG4108UMI ABC transporter, permease FOC92_RS16750 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS16755 ENOG4105D01 (LipO)protein FOC92_RS16760 ENOG4105CB2 alcohol dehydrogenase FOC92_RS16770 ENOG4105IQ5 FAD linked oxidase domain protein FOC92_RS16785 ENOG4105C2C drug resistance transporter, Bcr CflA FOC92_RS16800 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC92_RS16805 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC92_RS16810 ENOG4105C3U ABC transporter FOC92_RS16815 ENOG4108JQ7 (ABC) transporter FOC92_RS16845 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC92_RS16850 ENOG4108J59 Extracellular solute-binding protein, family 5 FOC92_RS16870 ENOG4105E0C molybdate abc transporter FOC92_RS16875 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC92_RS16880 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family FOC92_RS16890 ENOG4105EGI Transcriptional regulator FOC92_RS16910 ENOG4105F6E Acyl-transferase FOC92_RS16930 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) FOC92_RS16945 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) FOC92_RS16965 ENOG4105C5H ABC transporter FOC92_RS16975 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein FOC92_RS16985 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC92_RS16990 ENOG4105C3U ABC transporter FOC92_RS16995 ENOG4108JQ7 (ABC) transporter FOC92_RS17000 ENOG410667J hydrolase FOC92_RS17030 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase FOC92_RS17035 ENOG4105ERH Fumarylacetoacetate hydrolase FOC92_RS17045 ENOG4105CUB amino acid FOC92_RS17050 ENOG4108SC4 )-transporter FOC92_RS17055 ENOG4105CPF Cell wall formation (By similarity) FOC92_RS17060 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) FOC92_RS17085 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein FOC92_RS17090 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC92_RS17100 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) FOC92_RS17205 ENOG4105K8N protein family UPF0079, ATPase FOC92_RS17210 ENOG41072GX Peptidase M22 Glycoprotease FOC92_RS17215 ENOG410801F ribosomal-protein-alanine acetyltransferase FOC92_RS17220 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) FOC92_RS17225 ENOG4105C5H ABC transporter FOC92_RS17240 ENOG4108TYN CAAX amino terminal protease family protein FOC92_RS17260 ENOG4105C7N Xanthine uracil vitamin C permease FOC92_RS17270 ENOG4105BZU Histidine kinase FOC92_RS17295 ENOG4107ZXU DSBA oxidoreductase FOC92_RS17340 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS17380 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) FOC92_RS17390 ENOG4108SHN Glycosyl transferase, family 2 FOC92_RS17410 ENOG4105SX7 Transporter FOC92_RS17435 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) FOC92_RS17440 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit FOC92_RS17445 ENOG4105C83 adenylosuccinate lyase FOC92_RS17455 ENOG4105VR9 phosphoribosylformylglycinamidine synthase FOC92_RS17480 ENOG4108V3E phosphoribosylglycinamide formyltransferase FOC92_RS17490 ENOG4105C12 Phosphoribosylglycinamide synthetase FOC92_RS17515 ENOG4105C4R Atp-dependent dna helicase FOC92_RS17520 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) FOC92_RS17540 ENOG4108W2Y isochorismatase FOC92_RS17545 ENOG4108IDU Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS17550 ENOG4108UMI ABC transporter, permease FOC92_RS17555 ENOG4105D01 (LipO)protein FOC92_RS17575 ENOG410834F Transcriptional regulator FOC92_RS17580 ENOG4107I77 yiaA/B two helix domain FOC92_RS17600 ENOG4105CBD Diacylglycerol kinase FOC92_RS17605 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) FOC92_RS17610 ENOG4108JPW Aminotransferase FOC92_RS17620 ENOG4105C26 Dehydrogenase FOC92_RS17625 ENOG4105KPY Small multidrug resistance protein FOC92_RS17655 ENOG4105D9N nucleoside FOC92_RS17660 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC92_RS17680 ENOG4108W15 Protein of unknown function (DUF1456) FOC92_RS17695 ENOG4105DTQ mandelate racemase muconate lactonizing FOC92_RS17705 ENOG4105DFD Na H antiporter FOC92_RS17725 ENOG4105D3R alkyl hydroperoxide reductase FOC92_RS17745 ENOG4105EHG Permease protein FOC92_RS17750 ENOG4105DQ5 transport system permease protein FOC92_RS17755 ENOG4108V5C ABC transporter FOC92_RS17775 ENOG4106UIA FOC92_RS17780 ENOG4106UIA FOC92_RS17795 ENOG4105BZU Histidine kinase FOC92_RS17815 ENOG410756H nucleotidyltransferase FOC92_RS17820 ENOG4105D2S major facilitator superfamily FOC92_RS17835 ENOG4105E5Q amino acid AbC transporter FOC92_RS17840 ENOG4105EAB amino acid AbC transporter FOC92_RS17850 ENOG4105C8Q Methyl-accepting chemotaxis FOC92_RS17865 ENOG4105DBV ornithine carbamoyltransferase FOC92_RS17875 ENOG4105C5B carbamate kinase FOC92_RS17880 ENOG4108W63 CRP FNR family transcriptional regulator FOC92_RS17890 ENOG4105DNP FAD linked oxidase domain protein FOC92_RS17900 ENOG4105CI1 PTS System FOC92_RS17915 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC92_RS17930 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter FOC92_RS17950 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC92_RS17990 ENOG41062JF Transcriptional regulator FOC92_RS18005 ENOG4105DEU major facilitator superfamily FOC92_RS18020 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) FOC92_RS18035 ENOG4108N0M stress protein FOC92_RS18040 ENOG4106FN3 tellurium resistance protein FOC92_RS18045 ENOG4106FN3 tellurium resistance protein FOC92_RS18050 ENOG4107TS3 membrane protein, TerC FOC92_RS18055 ENOG4108TTB tellurium resistance protein FOC92_RS18075 ENOG4105KJF protein tyrosine phosphatase FOC92_RS18085 ENOG4107U9T Pfam:Ribonuclease_BN FOC92_RS18090 ENOG4105C59 p-type ATPase FOC92_RS18095 ENOG4108IPJ Membrane FOC92_RS18115 ENOG4107ZTW SNARE associated Golgi FOC92_RS18130 ENOG410606W general stress protein FOC92_RS18135 ENOG4105UPD Calcium Proton FOC92_RS18170 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) FOC92_RS18175 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) FOC92_RS18185 ENOG4108JUB Transcriptional regulator FOC92_RS18195 ENOG4108IQI permease FOC92_RS18235 ENOG4108A04 Beta-lactamase FOC92_RS18250 ENOG4105CKK Glycosyl transferase, family 2 FOC92_RS18255 ENOG4107QQG Dehydrogenase FOC92_RS18260 ENOG4105C3I Nad-dependent epimerase dehydratase FOC92_RS18280 ENOG4105F1A Pyruvate formate-lyase FOC92_RS18285 ENOG4108QBV Monogalactosyldiacylglycerol synthase FOC92_RS18300 ENOG4105CI2 imidazolone-5-propionate hydrolase FOC92_RS18305 ENOG4105ECP epimerase FOC92_RS18335 ENOG41067AE Membrane-bound metal-dependent hydrolase FOC92_RS18340 ENOG4105CEN a g-specific adenine glycosylase FOC92_RS18345 ENOG4106BXE FOC92_RS18365 ENOG4105BZ1 (ABC) transporter FOC92_RS18370 ENOG4107NBY Membrane FOC92_RS18375 ENOG4105CBC glutamate synthase FOC92_RS18385 ENOG4108IUW ABC transporter FOC92_RS18405 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC92_RS18410 ENOG4105G5W regulator Fur family FOC92_RS18530 ENOG4108JQC penicillin-binding protein 1A FOC92_RS18535 ENOG4108R9S DSBA oxidoreductase FOC92_RS18545 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) FOC92_RS18555 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) FOC92_RS18565 ENOG4105CYN Serine protein kinase FOC92_RS18585 ENOG4105C94 Transporter FOC92_RS18600 ENOG4105DZ6 Band 7 protein FOC92_RS18610 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism FOC92_RS18615 ENOG4108V9W transcriptional regulatory protein FOC92_RS18620 ENOG4105D4T Citrate transporter FOC92_RS18645 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC92_RS18650 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS18655 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component FOC92_RS18660 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component FOC92_RS18665 ENOG4105BZ7 extracellular solute-binding protein family 1 FOC92_RS18670 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) FOC92_RS18675 ENOG4108STX response regulator FOC92_RS18680 ENOG41062D9 Histidine kinase FOC92_RS18705 ENOG4108MRH transcriptional regulatory protein FOC92_RS18715 ENOG4105C6K Malic enzyme FOC92_RS18725 ENOG4108UZ3 Transporter FOC92_RS18730 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS18740 ENOG4105BZU Histidine kinase FOC92_RS18745 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS18750 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC92_RS18755 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) FOC92_RS18760 ENOG4108JB9 formate dehydrogenase FOC92_RS18780 ENOG4105CUB amino acid FOC92_RS18795 ENOG4105C59 p-type ATPase FOC92_RS18800 ENOG4105DAP Nicotinate phosphoribosyltransferase FOC92_RS18835 ENOG41073R8 VanW family FOC92_RS18840 ENOG4108KGH TRANSCRIPTIONal FOC92_RS18845 ENOG4105D9N nucleoside FOC92_RS18850 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase FOC92_RS18855 ENOG4105C37 (CBS) domain FOC92_RS18860 ENOG4108IJ0 Aspartate ammonia-lyase FOC92_RS18865 ENOG4105DAA L-lactate FOC92_RS18880 ENOG4105DUX Transporter FOC92_RS18885 ENOG4108MES Periplasmic binding protein FOC92_RS18890 ENOG4105DQ5 transport system permease protein FOC92_RS18895 ENOG4108IHU transport system permease protein FOC92_RS18900 ENOG4105E0A ABC, transporter FOC92_RS18905 ENOG4105DMQ Methyltransferase FOC92_RS18910 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) FOC92_RS18915 ENOG4105EXW epimerase dehydratase FOC92_RS18925 ENOG4107T89 von Willebrand factor, type A FOC92_RS18930 ENOG4105GMT ATPase associated with various cellular activities aaa_5 FOC92_RS18935 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC92_RS18945 ENOG4105BZU Histidine kinase FOC92_RS18955 ENOG4105D5Q Arginine ornithine antiporter FOC92_RS18960 ENOG4107414 GntR family transcriptional regulator FOC92_RS18965 ENOG4105C5Y PTS System FOC92_RS18970 ENOG4105CG3 alpha amylase, catalytic region FOC92_RS18985 ENOG4105E1K spore germination protein FOC92_RS18990 ENOG4105CRN Aminoglycoside phosphotransferase FOC92_RS19000 ENOG4105CDA abc transporter atp-binding protein FOC92_RS19005 ENOG4105CT1 (ABC) transporter FOC92_RS19010 ENOG4105EAD ABC transporter FOC92_RS19015 ENOG4105DRP amino acid AbC transporter FOC92_RS19020 ENOG4108IQI permease FOC92_RS19035 ENOG4105GFR rna polymerase sigma factor FOC92_RS19045 ENOG4105D29 Helix-turn-helix type 11 domain protein FOC92_RS19050 ENOG4105NAE bifunctional deaminase-reductase domain protein FOC92_RS19055 ENOG4105BZU Histidine kinase FOC92_RS19060 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS19070 ENOG4105CHH sulfate transporter FOC92_RS19075 ENOG41068KF Universal stress protein FOC92_RS19085 ENOG4105CXY transporter FOC92_RS19090 ENOG41067TZ transcriptional regulator, MarR family FOC92_RS19095 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS19100 ENOG4105ETE Transcriptional regulator (LacI family FOC92_RS19105 ENOG4108RVA ribokinase FOC92_RS19115 ENOG4105C2J ABC transporter FOC92_RS19120 ENOG4105CNN ABC, transporter FOC92_RS19125 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator FOC92_RS19130 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) FOC92_RS19170 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) FOC92_RS19200 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC92_RS19205 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer FOC92_RS19210 ENOG41069ER domain protein FOC92_RS19215 ENOG4105VZ8 Transcriptional regulator FOC92_RS19220 ENOG4107D63 FOC92_RS19235 ENOG4105DUX Transporter FOC92_RS19255 ENOG4105C85 amino acid FOC92_RS19260 ENOG4105C7N Xanthine uracil vitamin C permease FOC92_RS19275 ENOG4105MA6 gCN5-related N-acetyltransferase FOC92_RS19295 ENOG4105CCU oxidase (Subunit III) FOC92_RS19300 ENOG4105BZ9 Cytochrome C oxidase, subunit I FOC92_RS19305 ENOG4105E2S oxidase) subunit II FOC92_RS19330 ENOG4105E1V na solute symporter FOC92_RS19345 ENOG4108NHD germination protein FOC92_RS19355 ENOG4105CE1 Ferrous iron transport protein b FOC92_RS19360 ENOG4105CE1 Ferrous iron transport protein b FOC92_RS19365 ENOG4105CE1 Ferrous iron transport protein b FOC92_RS19370 ENOG4105CVA phosphate FOC92_RS19375 ENOG4105C8U phosphate abc transporter FOC92_RS19500 ENOG41080XQ Signal transduction protein with cbs domains FOC92_RS19520 ENOG4105ETU transcriptional activator (TenA FOC92_RS19530 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component FOC92_RS19540 ENOG4108VEU Thiamine monophosphate synthase FOC92_RS19545 ENOG41080HI glycine oxidase FOC92_RS19560 ENOG4105D06 uba thif-type nad fad binding protein FOC92_RS19565 ENOG4105DWF phosphomethylpyrimidine kinase FOC92_RS19615 ENOG4108INS Transcriptional regulator FOC92_RS19640 ENOG4105C19 ABC transporter FOC92_RS19650 ENOG4105C7N Xanthine uracil vitamin C permease FOC92_RS19660 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein FOC92_RS19675 ENOG4105K63 Thioredoxin FOC92_RS19695 ENOG4108B31 Spore germination protein FOC92_RS19715 ENOG4107Y03 Nitroreductase FOC92_RS19720 ENOG4105ED1 spovr family FOC92_RS19730 ENOG4108TCS Glutamyl endopeptidase FOC92_RS19735 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase FOC92_RS19740 ENOG4105XTG Pfam:DUF156 FOC92_RS19745 ENOG4105VFE sira family FOC92_RS19750 ENOG4107TPS domain protein FOC92_RS19755 ENOG4105VFE sira family FOC92_RS19760 ENOG4105VFE sira family FOC92_RS19770 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase FOC92_RS19775 ENOG41087NI Sulfite exporter TauE/SafE FOC92_RS19785 ENOG4108KGH TRANSCRIPTIONal FOC92_RS19810 ENOG4105EMD TRANSCRIPTIONal FOC92_RS19815 ENOG4105VCP PTS System FOC92_RS19820 ENOG4105VZJ PTS System FOC92_RS19845 ENOG41069ER domain protein FOC92_RS19850 ENOG4107RBB ABC transporter, permease FOC92_RS19855 ENOG4105C19 ABC transporter FOC92_RS19885 ENOG4105WEF catalase FOC92_RS19920 ENOG4107T5V SNARE associated Golgi FOC92_RS19955 ENOG4105CUB amino acid FOC92_RS19960 ENOG4107RWR Sodium hydrogen exchanger FOC92_RS19970 ENOG4106KNT transcriptional regulator FOC92_RS20010 ENOG4108YXU transcriptional regulator AsnC family FOC92_RS20015 ENOG4105CH7 arginosuccinase FOC92_RS20020 ENOG4105UBK short-chain dehydrogenase reductase FOC92_RS20065 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC92_RS20070 ENOG4105E5W Transporter FOC92_RS20085 ENOG4107RKG DJ-1/PfpI family FOC92_RS20090 ENOG4105CH6 catalase FOC92_RS20100 ENOG4105D5Q Arginine ornithine antiporter FOC92_RS20105 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) FOC92_RS20115 ENOG4105C26 Dehydrogenase FOC92_RS20120 ENOG4105BZ1 (ABC) transporter FOC92_RS20125 ENOG4105BZ1 (ABC) transporter FOC92_RS20135 ENOG4105DRP amino acid AbC transporter FOC92_RS20140 ENOG4105CDA abc transporter atp-binding protein FOC92_RS20155 ENOG410839P FOC92_RS20165 ENOG4108UH6 UPF0754 membrane protein FOC92_RS20180 ENOG4105BZU Histidine kinase FOC92_RS20185 ENOG4105WH1 Two component transcriptional regulator luxr family FOC92_RS20235 ENOG4107FQX Alpha-acetolactate decarboxylase FOC92_RS20245 ENOG4108VX5 3-methyladenine DNA glycosylase FOC92_RS20260 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase FOC92_RS20265 ENOG4105D4P Coproporphyrinogen iii oxidase FOC92_RS20270 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS20285 ENOG4105CHH sulfate transporter FOC92_RS20310 ENOG4105CGU Enoyl-CoA hydratase FOC92_RS20330 ENOG4105DER m42 family FOC92_RS20375 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC92_RS20385 ENOG4108JQ7 (ABC) transporter FOC92_RS20400 ENOG4105IGJ Zn-dependent Hydrolase of the beta-lactamase fold protein FOC92_RS20460 ENOG4108IBT Inherit from COG: transposase FOC92_RS20515 ENOG4105CSH Transporter FOC92_RS20525 ENOG4108MRH transcriptional regulatory protein FOC92_RS20545 ENOG4107SCJ type I restriction enzyme EcoKI subunit R FOC92_RS20590 ENOG4105CDU Replicative dna helicase FOC92_RS20615 ENOG4108Z86 Glutamine amidotransferase FOC92_RS20635 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS20655 ENOG4105D9U N-acetyltransferase FOC92_RS20710 ENOG4105F6J Alpha beta hydrolase fold FOC92_RS20760 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC92_RS20775 ENOG4108NIW Leucine export protein LeuE FOC92_RS20780 ENOG4105CMT Dihydroxyacetone kinase FOC92_RS20790 ENOG4105CMT Dihydroxyacetone kinase FOC92_RS20885 ENOG4105WN5 stage II sporulation protein FOC92_RS20895 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS20905 ENOG4108MJI response regulator FOC92_RS20910 ENOG4105BZU Histidine kinase FOC92_RS20915 ENOG4105BZU Histidine kinase FOC92_RS20955 ENOG4105D7V transposase FOC92_RS20965 ENOG4107QHE Choloylglycine hydrolase FOC92_RS20985 ENOG4107VRP DNA repair exonuclease FOC92_RS20990 ENOG4106D4I domain protein FOC92_RS21000 ENOG4105ED2 Beta-lactamase FOC92_RS21035 ENOG4108MUZ hydrolase FOC92_RS21055 ENOG4105F0F Oxalate decarboxylase FOC92_RS21065 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator FOC92_RS21080 ENOG4105C6V Glycerol-3-phosphate dehydrogenase FOC92_RS21100 ENOG4105DU6 RNA polymerase FOC92_RS21110 ENOG4105CNI cell division protein FtsW FOC92_RS21115 ENOG4105EEM helicase FOC92_RS21120 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC92_RS21145 ENOG4105K59 histidine triad (HIT) protein FOC92_RS21180 ENOG410905X membrane-flanked domain protein FOC92_RS21185 ENOG4105CKV Membrane FOC92_RS21225 ENOG410905X membrane-flanked domain protein FOC92_RS21235 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation FOC92_RS21240 ENOG4105BZ4 penicillin-binding protein FOC92_RS21250 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FOC92_RS21255 ENOG4105C1Q protoporphyrinogen oxidase FOC92_RS21280 ENOG4105NA0 Transcriptional regulator FOC92_RS21295 ENOG4105ECB domain protein FOC92_RS21295 ENOG4105ECB domain protein FOC92_RS21325 ENOG4106AXD FOC92_RS21330 ENOG4108RQ5 Beta-lactamase domain-containing protein FOC92_RS21335 ENOG4105DF9 Lipoate-protein, ligase FOC92_RS21345 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS21355 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein FOC92_RS21360 ENOG4108I5D sulfate abc transporter FOC92_RS21365 ENOG4105ECW sulfate abc transporter FOC92_RS21370 ENOG4108IJ6 ABC transporter FOC92_RS21385 ENOG4107RN3 metallophosphoesterase FOC92_RS21390 ENOG4107TVP HD domain protein FOC92_RS21400 ENOG4108AEY RNA polymerase sigma factor FOC92_RS21405 ENOG41086D8 Transcriptional regulator FOC92_RS21420 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS21440 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 FOC92_RS21445 ENOG4105C8Q Methyl-accepting chemotaxis FOC92_RS21450 ENOG4105D9F endo-1,4-beta-xylanase (EC 3.2.1.8) FOC92_RS21460 ENOG4107QP3 malate synthase g FOC92_RS21560 ENOG4105ERH Fumarylacetoacetate hydrolase FOC92_RS21570 ENOG4105C8Y Acetylornithine aminotransferase FOC92_RS21585 ENOG4105CAQ asparagine synthetase FOC92_RS21590 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) FOC92_RS21595 ENOG4105CH6 catalase FOC92_RS21600 ENOG4105BZU Histidine kinase FOC92_RS21620 ENOG4105QNR S1 RNA binding domain protein FOC92_RS21625 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC92_RS21635 ENOG4107AYK membrAne FOC92_RS21640 ENOG41073B9 FOC92_RS21650 ENOG4108KP7 hydrolase FOC92_RS21660 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit FOC92_RS21685 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) FOC92_RS21690 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) FOC92_RS21705 ENOG4105C31 Tryptophanyl-tRNA synthetase FOC92_RS21720 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component FOC92_RS21725 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component FOC92_RS21735 ENOG4108JQ7 (ABC) transporter FOC92_RS21740 ENOG4105UQX Mate efflux family protein FOC92_RS21760 ENOG4108ZCF integral membrane protein FOC92_RS21770 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC92_RS21780 ENOG4105DPN Oligoendopeptidase f FOC92_RS21795 ENOG4108Z18 K06886 hemoglobin FOC92_RS21800 ENOG4105MIX Adenylate cyclase FOC92_RS21815 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) FOC92_RS21820 ENOG4105EMS pseudouridine synthase FOC92_RS21840 ENOG4105K64 Glycosyl transferase, family 2 FOC92_RS21860 ENOG4107TVC Glycosyl transferase, family 2 FOC92_RS21880 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) FOC92_RS21885 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase FOC92_RS21895 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase FOC92_RS21970 ENOG4105CK7 Sodium proline symporter FOC92_RS21980 ENOG4105DDQ anthranilate synthase FOC92_RS21990 ENOG4105DK0 Indole-3-glycerol phosphate synthase FOC92_RS22060 ENOG41089UC methyltransferase, type 11 FOC92_RS22080 ENOG4105C7S Dehydrogenase FOC92_RS22085 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 FOC92_RS22120 ENOG4108IUX (ABC) transporter FOC92_RS22125 ENOG4105RHA ABC transporter, permease FOC92_RS22150 ENOG4105DZ1 carboxypeptidase FOC92_RS22155 ENOG4105VFR signal peptidase FOC92_RS22190 ENOG4105C26 Dehydrogenase FOC92_RS22195 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS22200 ENOG4105F38 ABC transporter, permease FOC92_RS22205 ENOG4105D38 putrescine abc transporter FOC92_RS22210 ENOG4108HM4 ABC transporter FOC92_RS22220 ENOG4105EYF MMPL domain protein FOC92_RS22230 ENOG4108YBP pseudouridine synthase FOC92_RS22240 ENOG4105K4I Scp-like extracellular FOC92_RS22245 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) FOC92_RS22250 ENOG4105CQB FAD linked oxidase domain protein FOC92_RS22265 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS22270 ENOG4105BZU Histidine kinase FOC92_RS22275 ENOG4105JXH GntR family transcriptional regulator FOC92_RS22295 ENOG4106A3R peptidase FOC92_RS22305 ENOG4108QTI )-transporter FOC92_RS22310 ENOG4107TS3 membrane protein, TerC FOC92_RS22315 ENOG4105CZN Potassium uptake protein FOC92_RS22320 ENOG410681C small acid-soluble spore protein FOC92_RS22325 ENOG4108Z7G MaoC domain protein dehydratase FOC92_RS22345 ENOG4105CHR reductase FOC92_RS22375 ENOG4105C4Y ABC transporter FOC92_RS22380 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) FOC92_RS22385 ENOG4107RCV ABC transporter, permease FOC92_RS22405 ENOG4105E98 transcriptional regulator DeoR family FOC92_RS22415 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) FOC92_RS22425 ENOG4105PXI polysaccharide deacetylase FOC92_RS22435 ENOG4105BZU Histidine kinase FOC92_RS22440 ENOG41090MY MarR family Transcriptional regulator FOC92_RS22450 ENOG4106DF1 FOC92_RS22455 ENOG4105BZU Histidine kinase FOC92_RS22460 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) FOC92_RS22465 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase FOC92_RS22470 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) FOC92_RS22510 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) FOC92_RS22515 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC92_RS22520 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) FOC92_RS22525 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS22530 ENOG4105CZV ABC transporter FOC92_RS22540 ENOG4105CJ1 ABC, transporter FOC92_RS22580 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A FOC92_RS22585 ENOG4105EA8 2-Nitropropane dioxygenase FOC92_RS22590 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC92_RS22600 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein FOC92_RS22625 ENOG4105NQC Flavodoxin FOC92_RS22695 ENOG4105CZN Potassium uptake protein FOC92_RS22700 ENOG41063Y9 FOC92_RS22705 ENOG4105KBJ sporulation protein ytfj FOC92_RS22725 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC92_RS22730 ENOG4105C7K acetolactate synthase FOC92_RS22735 ENOG4108ZP8 Acetolactate synthase small subunit FOC92_RS22740 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FOC92_RS22755 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) FOC92_RS22770 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) FOC92_RS22775 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) FOC92_RS22780 ENOG4105ECC imidazole-glycerol-phosphate dehydratase FOC92_RS22785 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) FOC92_RS22790 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase FOC92_RS22795 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) FOC92_RS22810 ENOG4107RVV histidinol phosphate phosphatase, hisj family FOC92_RS22825 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase FOC92_RS22830 ENOG4105E0M Sulfatase FOC92_RS22840 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) FOC92_RS22855 ENOG4107S4M Sulfate adenylate transferase FOC92_RS22860 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) FOC92_RS22865 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) FOC92_RS22875 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC92_RS22880 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC92_RS22885 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC92_RS22890 ENOG4105C8J )-transporter FOC92_RS22920 ENOG4105DFD Na H antiporter FOC92_RS22940 ENOG4105ENE Histidine kinase FOC92_RS22945 ENOG4105WH1 Two component transcriptional regulator luxr family FOC92_RS22965 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC92_RS22990 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) FOC92_RS23010 ENOG4105CJ3 phosphate transporter FOC92_RS23015 ENOG4107GRR phosphate transport regulator FOC92_RS23020 ENOG4105BZ4 penicillin-binding protein FOC92_RS23035 ENOG4105BZU Histidine kinase FOC92_RS23040 ENOG4105I3N Conserved Protein FOC92_RS23055 ENOG4105BZU Histidine kinase FOC92_RS23085 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) FOC92_RS23090 ENOG4105DZ1 carboxypeptidase FOC92_RS23095 ENOG4108JIC nucleoside recognition domain protein FOC92_RS23105 ENOG4105FE9 pseudouridine synthase FOC92_RS23110 ENOG4105KJP alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC92_RS23115 ENOG4107TWT Cytochrome c biogenesis protein FOC92_RS23120 ENOG4105CRE cytochrome C FOC92_RS23125 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS23130 ENOG4105BZU Histidine kinase FOC92_RS23135 ENOG4108WBT adenosyltransferase FOC92_RS23150 ENOG4108SAX Membrane FOC92_RS23165 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC92_RS23170 ENOG4105I7S Abortive infection protein FOC92_RS23180 ENOG4107RGJ metallophosphoesterase FOC92_RS23185 ENOG4108XDN Transcriptional regulator FOC92_RS23190 ENOG4108S6Z Negative regulator of genetic competence FOC92_RS23215 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase FOC92_RS23220 ENOG4107RB3 L-asparaginase FOC92_RS23240 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) FOC92_RS23255 ENOG4105S2F FOC92_RS23260 ENOG41065D1 FOC92_RS23290 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) FOC92_RS23305 ENOG4105XXQ heptaprenyl diphosphate synthase component I FOC92_RS23315 ENOG4105EAH synthase FOC92_RS23320 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) FOC92_RS23325 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FOC92_RS23340 ENOG41068YB TPR repeat-containing protein FOC92_RS23355 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) FOC92_RS23360 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) FOC92_RS23395 ENOG4108JYZ YitT family FOC92_RS23400 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase FOC92_RS23415 ENOG4105FJR Lmbe family FOC92_RS23420 ENOG4105CPK Glycosyl transferase (Group 1 FOC92_RS23440 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) FOC92_RS23455 ENOG4105DVT helicase FOC92_RS23460 ENOG4105YAC FOC92_RS23480 ENOG4105CSM endonuclease III FOC92_RS23490 ENOG4105BZ4 penicillin-binding protein FOC92_RS23545 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) FOC92_RS23555 ENOG4105DVT helicase FOC92_RS23560 ENOG4105CTD carboxy-peptidase FOC92_RS23570 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) FOC92_RS23580 ENOG4105C2W permease FOC92_RS23585 ENOG4105DHF Membrane FOC92_RS23595 ENOG410890F Dynamin family FOC92_RS23605 ENOG4108W0I acetyltransferase FOC92_RS23615 ENOG4105KHC sulfurtransferase FOC92_RS23670 ENOG4105HTX biosynthesis protein FOC92_RS23700 ENOG4105CPK Glycosyl transferase (Group 1 FOC92_RS23715 ENOG4108SZE gCN5-related N-acetyltransferase FOC92_RS23735 ENOG41081VK Ribonuclease FOC92_RS23800 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC92_RS23810 ENOG4107RWR Sodium hydrogen exchanger FOC92_RS23815 ENOG4105CN5 Metallo-Beta-Lactamase FOC92_RS23820 ENOG4108Z5V transcriptional regulator, merr family FOC92_RS23830 ENOG4105H67 Protein of unknown function (DUF421) FOC92_RS23835 ENOG41080C8 DUF218 domain FOC92_RS23875 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) FOC92_RS23885 ENOG4107R0U MotA TolQ exbB proton channel FOC92_RS23890 ENOG4105ER2 Ompa motb domain protein FOC92_RS23895 ENOG4107YTP response regulator receiver protein FOC92_RS23900 ENOG4105CBS Chea signal transduction histidine kinase FOC92_RS23905 ENOG4105DD5 Flagellar motor switch protein FOC92_RS23920 ENOG4105BZU Histidine kinase FOC92_RS23940 ENOG4105E1Q flagellar hook-associated protein FOC92_RS23945 ENOG4105DTJ flagellar hook-associated protein FOC92_RS23950 ENOG4105DTS flagellar hook-associated FOC92_RS23965 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) FOC92_RS23970 ENOG4108ZC9 flagellar basal-body rod protein flgc FOC92_RS23980 ENOG4107U2N Flagellar M-ring protein FOC92_RS23985 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC92_RS24015 ENOG4105BZE flagellar hook protein, FlgE FOC92_RS24030 ENOG4107R88 Chemotaxis protein (CheV) FOC92_RS24040 ENOG4105I03 Flagellin FOC92_RS24045 ENOG4105I03 Flagellin FOC92_RS24050 ENOG4105E4C Lytic transglycosylase catalytic FOC92_RS24060 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) FOC92_RS24065 ENOG4105DD5 Flagellar motor switch protein FOC92_RS24075 ENOG4105CN7 Flagellar biosynthetic protein FliP FOC92_RS24080 ENOG4105VS8 Flagellar biosynthetic protein fliq FOC92_RS24090 ENOG4105D00 flagellar biosynthetic protein flhB FOC92_RS24095 ENOG4105D7B Flagellar biosynthesis protein flha FOC92_RS24100 ENOG4105FZW flagellar biosynthesis regulator FlhF FOC92_RS24105 ENOG4105KTQ flagellar basal-body rod protein FOC92_RS24110 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) FOC92_RS24145 ENOG4105KAC Antibiotic biosynthesis monooxygenase FOC92_RS24180 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein FOC92_RS24185 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component FOC92_RS24220 ENOG4105CVJ phosphoglycerate mutase FOC92_RS24230 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) FOC92_RS24250 ENOG4105CAQ asparagine synthetase FOC92_RS24270 ENOG4105PGM cation diffusion facilitator family transporter FOC92_RS24280 ENOG4105DRR Transcriptional regulator, GntR family FOC92_RS24285 ENOG4108UZ3 Transporter FOC92_RS24295 ENOG4105CKI cobalamin synthesis protein FOC92_RS24300 ENOG4108PJD permease FOC92_RS24315 ENOG4105DFD Na H antiporter FOC92_RS24320 ENOG4105VUF Transcriptional regulator FOC92_RS24330 ENOG4105C9Q fumarate hydratase class II FOC92_RS24350 ENOG4107QJQ Mate efflux family protein FOC92_RS24355 ENOG4105EC3 peptidase S51, dipeptidase E FOC92_RS24380 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen FOC92_RS24565 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) FOC92_RS24605 ENOG4105K63 Thioredoxin FOC92_RS24630 ENOG4105C2M dna polymerase I FOC92_RS24690 ENOG4106BRA Membrane FOC92_RS24725 ENOG4105CJ1 ABC, transporter FOC92_RS24750 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) FOC92_RS24760 ENOG4108IJ0 Aspartate ammonia-lyase FOC92_RS24765 ENOG4105C6K Malic enzyme FOC92_RS24815 ENOG4105FVX FOC92_RS24830 ENOG4105CSR polyphosphate kinase 2 FOC92_RS24835 ENOG4105U3E Transcriptional regulator FOC92_RS24845 ENOG4105DXI Major Facilitator superfamily FOC92_RS24855 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) FOC92_RS24860 ENOG4105EU0 Major facilitator Superfamily FOC92_RS24865 ENOG4105C6T cysteine synthase FOC92_RS24885 ENOG4105C8J )-transporter FOC92_RS24890 ENOG4105X5K response regulator receiver protein FOC92_RS24895 ENOG4105H67 Protein of unknown function (DUF421) FOC92_RS24915 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) FOC92_RS24920 ENOG4105CHR reductase FOC92_RS24925 ENOG4105CM2 brancheD-chain amino acid aminotransferase FOC92_RS24930 ENOG4105C7K acetolactate synthase FOC92_RS24940 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase FOC92_RS24945 ENOG4105C01 Dihydroxy-acid dehydratase FOC92_RS24950 ENOG4105C7B Threonine dehydratase FOC92_RS24975 ENOG4105C6X Major Facilitator FOC92_RS24980 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b FOC92_RS24990 ENOG4105DY9 regulatoR FOC92_RS24995 ENOG4105CYC Transferase FOC92_RS25000 ENOG4105K5X acetyltransferase FOC92_RS25020 ENOG41068WN FOC92_RS25040 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) FOC92_RS25055 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) FOC92_RS25060 ENOG4105C0X amino acid FOC92_RS25085 ENOG4105K8R UPF0145 protein FOC92_RS25100 ENOG4107RHR regulatoR FOC92_RS25110 ENOG4105D9N nucleoside FOC92_RS25115 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) FOC92_RS25135 ENOG4108IBT Inherit from COG: transposase FOC92_RS25165 ENOG4107RAQ aminopeptidase FOC92_RS25175 ENOG4107R16 Multicopper oxidase FOC92_RS25215 ENOG4108T5E Copper resistance protein FOC92_RS25220 ENOG4105KTB nuclear export factor GLE1 FOC92_RS25225 ENOG4107RT3 EamA-like transporter family FOC92_RS25230 ENOG4105GZI Transcriptional regulator FOC92_RS25235 ENOG4108Z40 Transcriptional regulator FOC92_RS25240 ENOG4107ZXU DSBA oxidoreductase FOC92_RS25245 ENOG4108TVJ Nitroreductase FOC92_RS25250 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) FOC92_RS25255 ENOG4106F5Q Membrane FOC92_RS25260 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) FOC92_RS25275 ENOG4105CKI cobalamin synthesis protein FOC92_RS25285 ENOG4105C0Z ABC transporter FOC92_RS25290 ENOG4108IV0 ABC, transporter FOC92_RS25295 ENOG4105C32 Amino acid ABC transporter (Permease) FOC92_RS25305 ENOG4105SKE transcriptional Regulator LysR family FOC92_RS25325 ENOG4105C4M (Ubiquinol oxidase) subunit I FOC92_RS25330 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii FOC92_RS25335 ENOG4108JJ9 ABC, transporter FOC92_RS25340 ENOG4108JJ8 (ABC) transporter FOC92_RS25350 ENOG4105K64 Glycosyl transferase, family 2 FOC92_RS25360 ENOG4108UT6 Transferase hexapeptide repeat containing protein FOC92_RS25415 ENOG4105BZ1 (ABC) transporter FOC92_RS25420 ENOG4105EFI regulatoR FOC92_RS25425 ENOG4105BZU Histidine kinase FOC92_RS25435 ENOG41075D4 Aminoglycoside 6-adenylyltransferase FOC92_RS25460 ENOG4105D6E homoserine dehydrogenase FOC92_RS25470 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) FOC92_RS25485 ENOG4108KGH TRANSCRIPTIONal FOC92_RS25495 ENOG4105DPZ Two component transcriptional regulator (Winged helix family FOC92_RS25500 ENOG4105BZU Histidine kinase FOC92_RS25515 ENOG4105KT7 mgtC SapB transporter FOC92_RS25530 ENOG4105DUU IucA IucC family protein FOC92_RS25535 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS25550 ENOG4108WBH protein TIM barrel FOC92_RS25555 ENOG4105YWU small acid-soluble spore protein FOC92_RS25565 ENOG4108ZUB Lysine exporter protein (Lyse ygga) FOC92_RS25570 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS25620 ENOG4105KRN Transcriptional regulator, abrb family FOC92_RS25630 ENOG4105YVS arsR family transcriptional regulator FOC92_RS25635 ENOG4105CPC Aldo Keto reductase FOC92_RS25640 ENOG4107XZQ multidrug resistance protein FOC92_RS25665 ENOG4105C8Q Methyl-accepting chemotaxis FOC92_RS25680 ENOG4108K88 Membrane FOC92_RS25685 ENOG4108WPJ Ferritin-like domain FOC92_RS25700 ENOG4105DEN Luciferase family FOC92_RS25715 ENOG4105VMI -acetyltransferase FOC92_RS25720 ENOG4107QM2 Aldo Keto reductase FOC92_RS25725 ENOG4105CKI cobalamin synthesis protein FOC92_RS25735 ENOG4105DSE periplasmic solute binding protein FOC92_RS25745 ENOG4105K4T epimerase FOC92_RS25755 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) FOC92_RS25800 ENOG4107T5V SNARE associated Golgi FOC92_RS25815 ENOG4108PJD permease FOC92_RS25825 ENOG4108S4H thioesterase Superfamily protein FOC92_RS25835 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) FOC92_RS25855 ENOG4105SXS Protein of unknown function (DUF456) FOC92_RS25860 ENOG4105C37 (CBS) domain FOC92_RS25880 ENOG4108Z7R Chaperone CsaA FOC92_RS25900 ENOG4108ZRV stage ii sporulation protein p FOC92_RS25910 ENOG4108VXD carboxy-peptidase FOC92_RS25940 ENOG4108ZRV stage ii sporulation protein p FOC92_RS25950 ENOG4108X4Q Hydrolase FOC92_RS25965 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) FOC92_RS25980 ENOG41087PP glycosyltransferase MGT family FOC92_RS25985 ENOG4108JYZ YitT family FOC92_RS25990 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS26020 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) FOC92_RS26055 ENOG4108MGT Required for secretion of EsxA and EsxB FOC92_RS26140 ENOG4105D7V transposase FOC92_RS26145 ENOG4105KBJ sporulation protein ytfj FOC92_RS26170 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) FOC92_RS26190 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FOC92_RS26200 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein FOC92_RS26205 ENOG4105EMN RNA polymerase sigma factor FOC92_RS26220 ENOG4105CNW domain protein FOC92_RS26230 ENOG4108V06 Glutathione peroxidase FOC92_RS26245 ENOG4105C7R Atpase associated with various cellular activities aaa_3 FOC92_RS26255 ENOG4108IUE nitrate reductase beta subunit FOC92_RS26260 ENOG4105R3A Nitrate reductase FOC92_RS26270 ENOG4107V6Q Cyclic nucleotide-binding domain FOC92_RS26275 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) FOC92_RS26280 ENOG4105D06 uba thif-type nad fad binding protein FOC92_RS26285 ENOG4105CVM Molybdenum cofactor synthesis domain protein FOC92_RS26290 ENOG4108ZAF Molybdopterin FOC92_RS26295 ENOG41067WU Molybdopterin converting factor (Subunit 1) FOC92_RS26320 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein FOC92_RS26325 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein FOC92_RS26330 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) FOC92_RS26335 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit FOC92_RS26340 ENOG4108IFG nitrite reductase, (NAD(P)H) FOC92_RS26345 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) FOC92_RS26380 ENOG4105MCT stage V sporulation protein S FOC92_RS26420 ENOG4105C5H ABC transporter FOC92_RS26435 ENOG4108UUM single-stranded DNA-binding protein FOC92_RS26460 ENOG4107YX5 Pfam:DUF548 FOC92_RS26465 ENOG4105C75 arginyL-tRNA synthetase FOC92_RS26490 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) FOC92_RS26515 ENOG4105C5S asparaginyl-tRNA synthetase FOC92_RS26520 ENOG4105C8J )-transporter FOC92_RS26540 ENOG4107XGZ Hydrolase FOC92_RS26545 ENOG4105CY2 Citrate transporter FOC92_RS26565 ENOG4105KD7 acetyltransferase FOC92_RS26575 ENOG4105VMP Transcriptional regulator FOC92_RS26580 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase FOC92_RS26605 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 FOC92_RS26620 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) FOC92_RS26625 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) FOC92_RS26635 ENOG4107RVG penicillin-binding protein FOC92_RS26640 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) FOC92_RS26645 ENOG4105E9Q Acyl-transferase FOC92_RS26650 ENOG4108UT2 hemolysin iii FOC92_RS26660 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) FOC92_RS26670 ENOG4108RCR degv family FOC92_RS26680 ENOG4108KF3 Electron transport protein SCO1 SenC FOC92_RS26685 ENOG4107Y70 Heat shock protein FOC92_RS26690 ENOG4105CAQ asparagine synthetase FOC92_RS26710 ENOG4108MES Periplasmic binding protein FOC92_RS26715 ENOG4105F0I Aminotransferase FOC92_RS26750 ENOG4105D8X mechanosensitive ion channel FOC92_RS26755 ENOG4105BZU Histidine kinase FOC92_RS26760 ENOG4105WH1 Two component transcriptional regulator luxr family FOC92_RS26765 ENOG4106KNT transcriptional regulator FOC92_RS26770 ENOG4107ZY0 Phenazine biosynthesis-like protein FOC92_RS26790 ENOG4105CMG Carbohydrate kinase FOC92_RS26795 ENOG4105C6Z Gluconate FOC92_RS26805 ENOG4108YV3 Protein of unknown function (DUF2711) FOC92_RS26835 ENOG4108IJ8 ABC transporter FOC92_RS26840 ENOG4105E90 ABC transporter FOC92_RS26875 ENOG4105C37 (CBS) domain FOC92_RS26900 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) FOC92_RS26915 ENOG4107S4Y M20 DapE family protein YgeY FOC92_RS26920 ENOG4108TSC N-acetyltransferase FOC92_RS26925 ENOG4108JUB Transcriptional regulator FOC92_RS26930 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein FOC92_RS26975 ENOG410841Q phosphoesterase PA-phosphatase related protein FOC92_RS26985 ENOG4105SZ6 Thioredoxin FOC92_RS27020 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC92_RS27085 ENOG4105BZ4 penicillin-binding protein FOC92_RS27095 ENOG4105CZM Major Facilitator FOC92_RS27100 ENOG4105W8X HesB YadR YfhF-family protein FOC92_RS27110 ENOG4105DXD 2-methylcitrate dehydratase FOC92_RS27115 ENOG4105CR4 methylisocitrate lyase FOC92_RS27120 ENOG4105C1G acyl-Coa dehydrogenase FOC92_RS27125 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase FOC92_RS27135 ENOG4105N14 lysine exporter protein LysE YggA FOC92_RS27140 ENOG4105E39 Enoyl-CoA hydratase FOC92_RS27155 ENOG4107RFY SbcCD D subunit FOC92_RS27160 ENOG4105EYH Exonuclease FOC92_RS27180 ENOG4105FCD Major Facilitator FOC92_RS27185 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase FOC92_RS27190 ENOG4105E4F Isochorismate synthase FOC92_RS27195 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase FOC92_RS27200 ENOG4105WQI isochorismatase FOC92_RS27205 ENOG4105CEY Amp-dependent synthetase and ligase FOC92_RS27210 ENOG4105WQT MbtH domain protein FOC92_RS27215 ENOG4105C0R drug resistance transporter emrb qaca subfamily FOC92_RS27230 ENOG4105K70 DNA-binding protein FOC92_RS27250 ENOG4105BZG amino acid carrier protein FOC92_RS27270 ENOG4105FE9 pseudouridine synthase FOC92_RS27275 ENOG4105C22 threonyL-tRNA synthetase FOC92_RS27280 ENOG4105C19 ABC transporter FOC92_RS27320 ENOG41081I9 integral membrane protein FOC92_RS27345 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC92_RS27355 ENOG4105EYF MMPL domain protein FOC92_RS27385 ENOG4105WCN acetyltransferase FOC92_RS27410 ENOG4105C1Q protoporphyrinogen oxidase FOC92_RS27420 ENOG41068WN FOC92_RS27450 ENOG4107V2S Transcriptional regulator FOC92_RS27455 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) FOC92_RS27475 ENOG4105DND Transcriptional regulator FOC92_RS27480 ENOG4108RPX mosc domain containing protein FOC92_RS27495 ENOG4105BZ1 (ABC) transporter FOC92_RS27500 ENOG4105BZ1 (ABC) transporter FOC92_RS27525 ENOG4108JCI Transcriptional regulator FOC92_RS27560 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) FOC92_RS27590 ENOG4105F32 YngK protein FOC92_RS27615 ENOG4105RD7 BadF BadG BcrA BcrD FOC92_RS27620 ENOG4105R9Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) FOC92_RS27625 ENOG4107STF Involved in phosphonate degradation (By similarity) FOC92_RS27635 ENOG4108INS Transcriptional regulator FOC92_RS27650 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) FOC92_RS27660 ENOG4105C1J atp-dependent rna helicase FOC92_RS27670 ENOG4108RZE Tetr family transcriptional regulator FOC92_RS27695 ENOG41088CC tellurite resistance protein tehB FOC92_RS27705 ENOG4108I0C methyltransferase FOC92_RS27710 ENOG4107RA9 decarboxylase FOC92_RS27715 ENOG4105K56 Transcriptional regulator FOC92_RS27720 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) FOC92_RS27745 ENOG4105CIN aminoacyl-histidine dipeptidase FOC92_RS27770 ENOG4105KRN Transcriptional regulator, abrb family FOC92_RS27780 ENOG4105EJ9 Membrane FOC92_RS27785 ENOG4105EQK -acetyltransferase FOC92_RS27825 ENOG4105W8Z 4'-phosphopantetheinyl transferase FOC92_RS27835 ENOG4105CHR reductase FOC92_RS27900 ENOG4108IMY Transcriptional regulator FOC92_RS27920 ENOG4108RZE Tetr family transcriptional regulator FOC92_RS27925 ENOG4105CAQ asparagine synthetase FOC92_RS27930 ENOG4108XG2 Histidine kinase FOC92_RS27940 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin FOC92_RS27965 ENOG4105EJQ L-serine dehydratase FOC92_RS27970 ENOG4105C44 Serine transporter FOC92_RS27990 ENOG4105F6S Spore photoproduct lyase FOC92_RS28000 ENOG4105CVK Glutamate decarboxylase FOC92_RS28010 ENOG4107QHE Choloylglycine hydrolase FOC92_RS28035 ENOG4107RVG penicillin-binding protein FOC92_RS28050 ENOG4107RF6 penicillin-binding protein FOC92_RS28055 ENOG4107RF6 penicillin-binding protein FOC92_RS28065 ENOG4105DIN metallophosphoesterase FOC92_RS28075 ENOG4105CJ1 ABC, transporter FOC92_RS28085 ENOG4107Z3H Transcriptional regulator, TetR family FOC92_RS28100 ENOG4105C1G acyl-Coa dehydrogenase FOC92_RS28105 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase FOC92_RS28110 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit FOC92_RS28115 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase FOC92_RS28120 ENOG4105E39 Enoyl-CoA hydratase FOC92_RS28125 ENOG4107QX3 carboxylase FOC92_RS28130 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) FOC92_RS28160 ENOG4105DBI uridine monophosphokinase FOC92_RS28180 ENOG4105DZ1 carboxypeptidase FOC92_RS28195 ENOG4105T9C HD domain FOC92_RS28205 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) FOC92_RS28225 ENOG41075H3 AraC family transcriptional regulator FOC92_RS28255 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) FOC92_RS28280 ENOG4107Y80 Major Facilitator superfamily FOC92_RS28290 ENOG4105KVH Transcriptional regulator FOC92_RS28295 ENOG41089UC methyltransferase, type 11 FOC92_RS28340 ENOG4105EFA 4-hydroxyphenylacetate FOC92_RS28355 ENOG4105CPQ Dehydrogenase FOC92_RS28365 ENOG410900G Protein of unknown function (DUF421) FOC92_RS28370 ENOG4108V4B ThiJ pfpI FOC92_RS28380 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein FOC92_RS28450 ENOG4105D6E homoserine dehydrogenase FOC92_RS28460 ENOG4105CPF Cell wall formation (By similarity) FOC92_RS28465 ENOG4105ETU transcriptional activator (TenA FOC92_RS28490 ENOG4105VTR Integrase FOC92_RS28515 ENOG4108IMY Transcriptional regulator FOC92_RS28545 ENOG4108NF7 phage-type endonuclease FOC92_RS28555 ENOG4108PNI recT protein FOC92_RS28580 ENOG4108SXZ UPF0302 protein FOC92_RS28610 ENOG4105KNA -acetyltransferase FOC92_RS28705 ENOG4108TFU terminase (Small subunit) FOC92_RS28800 ENOG4105XSJ toxin secretion phage lysis holin FOC92_RS28930 ENOG410667J hydrolase FOC92_RS28935 ENOG4105BZU Histidine kinase FOC92_RS28940 ENOG4107RF6 penicillin-binding protein FOC92_RS28965 ENOG4108JJB ABC transporter FOC92_RS28980 ENOG4108HGU Histidine kinase FOC92_RS29055 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS29060 ENOG4105GR3 Histidine kinase FOC92_RS29065 ENOG4105CB2 alcohol dehydrogenase FOC92_RS29070 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase FOC92_RS29075 ENOG4105CJN penicillin-binding protein FOC92_RS29120 ENOG4107SWG transcriptional regulator MERR family FOC92_RS29125 ENOG4108Z6Z Transcriptional regulator FOC92_RS29145 ENOG4107TXC Transcriptional regulator FOC92_RS29150 ENOG4105F27 Major Facilitator FOC92_RS29170 ENOG4107VXM glycerophosphoryl diester phosphodiesterase FOC92_RS29190 ENOG4107Y9U Membrane FOC92_RS29210 ENOG4105EGD dinuclear metal center protein, YbgI family FOC92_RS29235 ENOG4105FCD Major Facilitator FOC92_RS29250 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) FOC92_RS29285 ENOG4108XI2 Domain of unknown function (DUF1963) FOC92_RS29305 ENOG4108NRW Phospholipase, patatin family FOC92_RS29310 ENOG4105KWG Pfam:DUF1696 FOC92_RS29335 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) FOC92_RS29345 ENOG4105PKS Excinuclease abc c subunit domain protein FOC92_RS29385 ENOG4107VFR oxidoreductase FOC92_RS29420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS29425 ENOG4105BZU Histidine kinase FOC92_RS29445 ENOG4107WD8 ABC transporter, permease FOC92_RS29460 ENOG4105DY8 decarboxylase FOC92_RS29475 ENOG4108IUM Glycogen debranching enzyme FOC92_RS29485 ENOG4105CGH 5'-nucleotidase FOC92_RS29500 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) FOC92_RS29505 ENOG4105FDR Membrane FOC92_RS29510 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family FOC92_RS29560 ENOG4105MSI germination protein ypeb FOC92_RS29590 ENOG4107VWA Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity) FOC92_RS29595 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) FOC92_RS29600 ENOG4107Z3H Transcriptional regulator, TetR family FOC92_RS29630 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family FOC92_RS29645 ENOG4105E98 transcriptional regulator DeoR family FOC92_RS29660 ENOG41062ES Transcriptional regulator FOC92_RS29680 ENOG4107QKR Dehydrogenase FOC92_RS29690 ENOG4107RUY (E1 component), alpha subunit FOC92_RS29700 ENOG4105JHE Major Facilitator Superfamily FOC92_RS29710 ENOG4105E1F short-chain dehydrogenase reductase FOC92_RS29715 ENOG4105RHY Pfam:UPF0157 FOC92_RS29755 ENOG4107SQ8 Glycine betaine FOC92_RS29760 ENOG4108IJ7 Glycine betaine FOC92_RS29785 ENOG4105E66 phosphoriboisomerase A FOC92_RS29790 ENOG41082BV acetyltransferase FOC92_RS29795 ENOG4108M1A Chitin-binding protein FOC92_RS29825 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) FOC92_RS29830 ENOG4105MSB protein, conserved in bacteria FOC92_RS29855 ENOG4108Z7F N-acetyltransferase FOC92_RS29875 ENOG4105KEG ribosomal-protein-alanine acetyltransferase FOC92_RS29880 ENOG4105EEM helicase FOC92_RS29890 ENOG41066HZ AIG2-like family FOC92_RS29895 ENOG4105C9U ATP-dependent DNA helicase RecQ FOC92_RS29950 ENOG4108M1A Chitin-binding protein FOC92_RS29965 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) FOC92_RS29975 ENOG4105BZG amino acid carrier protein FOC92_RS29980 ENOG4105C26 Dehydrogenase FOC92_RS29985 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) FOC92_RS29995 ENOG4105CTU Proline racemase FOC92_RS30000 ENOG41080HI glycine oxidase FOC92_RS30010 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein FOC92_RS30045 ENOG4105DCI Phosphohydrolase FOC92_RS30050 ENOG4107T5V SNARE associated Golgi FOC92_RS30060 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD FOC92_RS30080 ENOG4105DTQ mandelate racemase muconate lactonizing FOC92_RS30095 ENOG4107SET aldo keto reductase FOC92_RS30130 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) FOC92_RS30135 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) FOC92_RS30140 ENOG4105BZU Histidine kinase FOC92_RS30145 ENOG4105CK6 Two component transcriptional regulator (Winged helix family FOC92_RS30165 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 FOC92_RS30180 ENOG4105DPN Oligoendopeptidase f FOC92_RS30185 ENOG4105EPR degv family FOC92_RS30245 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) FOC92_RS30250 ENOG4106K7D Major facilitator family transporter FOC92_RS30275 ENOG4107BMA Transglycosylase associated protein FOC92_RS30290 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) FOC92_RS30325 ENOG4105CHM Aminotransferase FOC92_RS30355 ENOG4105DVE abc transporter atp-binding protein FOC92_RS30405 ENOG4105C02 permease FOC92_RS30415 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) FOC92_RS30420 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component FOC92_RS30425 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein FOC92_RS30430 ENOG4105D7T ABC transporter FOC92_RS30455 ENOG4108AQF aminoglycoside N(3)-acetyltransferase FOC92_RS30505 ENOG4107VC0 DNA alkylation repair enzyme FOC92_RS30510 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase FOC92_RS30525 ENOG4108ZCF integral membrane protein FOC92_RS30530 ENOG4105E0M Sulfatase FOC92_RS30535 ENOG4105C5H ABC transporter FOC92_RS30540 ENOG4105EYF MMPL domain protein FOC92_RS30545 ENOG41082JN Transcriptional regulator FOC92_RS30570 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase FOC92_RS30575 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase FOC92_RS30595 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) FOC92_RS30620 ENOG41069ER domain protein FOC92_RS30630 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase FOC92_RS30635 ENOG4105DNP FAD linked oxidase domain protein FOC92_RS30665 ENOG4105D4B ABC, transporter FOC92_RS30675 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane FOC92_RS30685 ENOG4105DKT Transcriptional regulator FOC92_RS30700 ENOG41061GT Aldolase FOC92_RS30710 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) FOC92_RS30745 ENOG4105II7 pyrroline-5-carboxylate reductase FOC92_RS30755 ENOG4107258 Transcriptional regulator FOC92_RS30770 ENOG4105ECK Fatty Acid Desaturase FOC92_RS30780 ENOG4107RBI VanW family FOC92_RS30785 ENOG4105G6Z alkaline phosphatase FOC92_RS30795 ENOG4105VMP Transcriptional regulator FOC92_RS30815 ENOG41068WN FOC92_RS30840 ENOG4105C7R Atpase associated with various cellular activities aaa_3