locus-tag	class	description
FORC21_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC21_RS00015	COG2501	S4 domain
FORC21_RS00025	COG0187	DNA topoisomerase II activity
FORC21_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC21_RS00065	COG0516	GMP reductase activity
FORC21_RS00065	COG0517	IMP dehydrogenase activity
FORC21_RS00070	COG1686	Belongs to the peptidase S11 family
FORC21_RS00100	COG1428	Deoxynucleoside kinase
FORC21_RS00105	COG1428	Deoxynucleoside kinase
FORC21_RS00110	COG1335	isochorismatase
FORC21_RS00120	COG0590	tRNA wobble adenosine to inosine editing
FORC21_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC21_RS00185	COG1982	Orn Lys Arg decarboxylase major
FORC21_RS00195	COG0470	DNA polymerase III
FORC21_RS00200	COG1774	PSP1 C-terminal conserved region
FORC21_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC21_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC21_RS00225	COG2002	toxin-antitoxin pair type II binding
FORC21_RS00235	COG0084	hydrolase, TatD family'
FORC21_RS00255	COG4466	Protein conserved in bacteria
FORC21_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC21_RS00280	COG0251	oxidation-reduction process
FORC21_RS00310	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC21_RS00315	COG2002	toxin-antitoxin pair type II binding
FORC21_RS00320	COG2244	polysaccharide biosynthetic process
FORC21_RS00325	COG3956	TIGRFAM MazG family protein
FORC21_RS00330	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC21_RS00350	COG1098	S1 RNA binding domain
FORC21_RS00365	COG2208	phosphoserine phosphatase activity
FORC21_RS00375	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC21_RS00380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC21_RS00395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC21_RS00400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC21_RS00405	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC21_RS00410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_RS00415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC21_RS00420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC21_RS00425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC21_RS00430	COG1396	sequence-specific DNA binding
FORC21_RS00435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC21_RS00525	COG3880	PFAM UvrB UvrC protein
FORC21_RS00535	COG0542	response to heat
FORC21_RS00540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC21_RS00550	COG4956	integral membrane protein (PIN domain superfamily)
FORC21_RS00570	COG1045	serine acetyltransferase
FORC21_RS00585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC21_RS00590	COG3688	RNA-binding protein containing a PIN domain
FORC21_RS00605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC21_RS00610	COG0250	Participates in transcription elongation, termination and antitermination
FORC21_RS00615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC21_RS00635	COG2813	Specifically methylates the guanine in position
FORC21_RS00650	COG1358	cellular component organization or biogenesis
FORC21_RS00655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC21_RS00725	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC21_RS00785	COG0201	protein transport
FORC21_RS00795	COG0024	Methionine aminopeptidase
FORC21_RS00805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC21_RS00840	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FORC21_RS00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS00870	COG0489	protein tyrosine kinase activity
FORC21_RS00880	COG2194	sulfuric ester hydrolase activity
FORC21_RS00885	COG0726	polysaccharide deacetylase
FORC21_RS00965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FORC21_RS00970	COG4856	YbbR-like protein
FORC21_RS01010	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS01015	COG2011	ABC-type metal ion transport system permease component
FORC21_RS01020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC21_RS01025	COG1464	Belongs to the NlpA lipoprotein family
FORC21_RS01030	COG0604	alcohol dehydrogenase
FORC21_RS01040	COG0277	FAD linked oxidase domain protein
FORC21_RS01045	COG2271	Major facilitator Superfamily
FORC21_RS01055	COG2814	Major facilitator Superfamily
FORC21_RS01070	COG0601	transmembrane transport
FORC21_RS01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_RS01080	COG0444	Belongs to the ABC transporter superfamily
FORC21_RS01085	COG4608	Belongs to the ABC transporter superfamily
FORC21_RS01100	COG2207	Transcriptional regulator
FORC21_RS01115	COG4166	transmembrane transport
FORC21_RS01120	COG4166	transmembrane transport
FORC21_RS01125	COG0656	L-ascorbic acid biosynthetic process
FORC21_RS01150	COG4149	molybdate abc transporter
FORC21_RS01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC21_RS01160	COG1910	domain protein
FORC21_RS01180	COG0697	spore germination
FORC21_RS01195	COG0204	Acyl-transferase
FORC21_RS01210	COG1609	Transcriptional regulator
FORC21_RS01220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS01240	COG5298	Protein conserved in bacteria
FORC21_RS01270	COG0488	(ABC) transporter
FORC21_RS01285	COG0747	negative chemotaxis
FORC21_RS01290	COG0601	transmembrane transport
FORC21_RS01295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_RS01300	COG0444	Belongs to the ABC transporter superfamily
FORC21_RS01305	COG4608	Belongs to the ABC transporter superfamily
FORC21_RS01310	COG0561	phosphatase activity
FORC21_RS01340	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FORC21_RS01345	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC21_RS01360	COG0531	amino acid
FORC21_RS01365	COG2814	Major facilitator Superfamily
FORC21_RS01375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC21_RS01385	COG4294	response to UV
FORC21_RS01390	COG0705	Rhomboid family
FORC21_RS01400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC21_RS01405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC21_RS01410	COG0864	Transcriptional regulator
FORC21_RS01415	COG2337	Toxic component of a toxin-antitoxin (TA) module
FORC21_RS01420	COG2183	response to ionizing radiation
FORC21_RS01520	COG0802	atpase or kinase
FORC21_RS01525	COG1214	PFAM Peptidase M22, glycoprotease
FORC21_RS01530	COG0456	acetyltransferase
FORC21_RS01540	COG0488	(ABC) transporter
FORC21_RS01555	COG1266	CAAX protease self-immunity
FORC21_RS01575	COG2252	PERMEase
FORC21_RS01585	COG5002	protein histidine kinase activity
FORC21_RS01615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC21_RS01660	COG2205	protein histidine kinase activity
FORC21_RS01665	COG0745	RESPONSE REGULATOR receiver
FORC21_RS01695	COG2226	methyltransferase
FORC21_RS01705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC21_RS01715	COG1215	transferase activity, transferring glycosyl groups
FORC21_RS01735	COG0697	spore germination
FORC21_RS01765	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC21_RS01770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC21_RS01775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC21_RS01785	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC21_RS01800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC21_RS01810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC21_RS01820	COG0151	Belongs to the GarS family
FORC21_RS01850	COG0210	DNA helicase
FORC21_RS01860	COG4851	CamS sex pheromone cAM373 precursor
FORC21_RS01875	COG1335	isochorismatase
FORC21_RS01885	COG2011	ABC-type metal ion transport system permease component
FORC21_RS01890	COG1464	Belongs to the NlpA lipoprotein family
FORC21_RS01905	COG0003	Pfam Anion-transporting ATPase
FORC21_RS01910	COG1846	Transcriptional regulator
FORC21_RS01915	COG4682	membrane
FORC21_RS01935	COG1597	lipid kinase activity
FORC21_RS01945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC21_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS01960	COG2076	Multidrug Resistance protein
FORC21_RS01970	COG2309	aminopeptidase activity
FORC21_RS01985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS01995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC21_RS02010	COG4807	Protein conserved in bacteria
FORC21_RS02035	COG1757	Na H antiporter
FORC21_RS02040	COG1473	amidohydrolase
FORC21_RS02055	COG0450	alkyl hydroperoxide reductase
FORC21_RS02075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS02080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS02085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS02095	COG0492	ferredoxin-NADP+ reductase activity
FORC21_RS02110	COG0166	Belongs to the GPI family
FORC21_RS02135	COG5002	protein histidine kinase activity
FORC21_RS02155	COG3541	Predicted nucleotidyltransferase
FORC21_RS02165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_RS02165	COG0723	plastoquinol--plastocyanin reductase activity
FORC21_RS02175	COG0765	amino acid transport
FORC21_RS02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_RS02185	COG1126	abc transporter atp-binding protein
FORC21_RS02190	COG0840	transmembrane signaling receptor activity
FORC21_RS02215	COG0549	Belongs to the carbamate kinase family
FORC21_RS02220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_RS02230	COG0277	FAD linked oxidase domain protein
FORC21_RS02235	COG0366	Alpha amylase catalytic
FORC21_RS02240	COG1263	PTS System
FORC21_RS02240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_RS02240	COG2190	(PTS) system
FORC21_RS02270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC21_RS02290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_RS02295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_RS02300	COG1116	anion transmembrane transporter activity
FORC21_RS02305	COG0488	(ABC) transporter
FORC21_RS02360	COG2270	Major facilitator Superfamily
FORC21_RS02390	COG2310	stress, protein
FORC21_RS02395	COG2310	stress, protein
FORC21_RS02400	COG2310	stress, protein
FORC21_RS02405	COG0861	Integral membrane protein TerC family
FORC21_RS02415	COG3853	Toxic anion resistance protein (TelA)
FORC21_RS02430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC21_RS02440	COG1295	ribonuclease BN
FORC21_RS02450	COG2217	Heavy metal translocating P-type atpase
FORC21_RS02455	COG0697	spore germination
FORC21_RS02465	COG0681	Belongs to the peptidase S26 family
FORC21_RS02475	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS02490	COG3871	stress protein (general stress protein 26)
FORC21_RS02495	COG0387	Pfam Sodium calcium exchanger
FORC21_RS02505	COG0535	radical SAM domain protein
FORC21_RS02525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC21_RS02530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC21_RS02545	COG3829	transcription factor binding
FORC21_RS02555	COG0833	amino acid
FORC21_RS02560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC21_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_RS02595	COG1263	PTS System
FORC21_RS02600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_RS02615	COG0463	Glycosyl transferase, family 2
FORC21_RS02625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC21_RS02625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC21_RS02645	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC21_RS02665	COG1228	amidohydrolase
FORC21_RS02670	COG1090	epimerase
FORC21_RS02700	COG1988	membrane-bound metal-dependent
FORC21_RS02705	COG1194	a g-specific adenine glycosylase
FORC21_RS02730	COG1132	(ABC) transporter
FORC21_RS02735	COG4129	membrane
FORC21_RS02740	COG0069	glutamate synthase activity
FORC21_RS02740	COG0067	glutamate synthase
FORC21_RS02740	COG0070	glutamate synthase
FORC21_RS02750	COG4555	ABC transporter
FORC21_RS02770	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC21_RS02775	COG0735	belongs to the Fur family
FORC21_RS02900	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC21_RS02925	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC21_RS02940	COG2766	serine protein kinase
FORC21_RS02965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC21_RS02975	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC21_RS02980	COG2268	Band 7 protein
FORC21_RS02990	COG3290	protein histidine kinase activity
FORC21_RS02995	COG4565	transcriptional regulatory protein
FORC21_RS03000	COG2851	Citrate transporter
FORC21_RS03025	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC21_RS03030	COG3842	ATPase activity
FORC21_RS03035	COG1175	transmembrane transport
FORC21_RS03040	COG0395	ABC-type sugar transport system, permease component
FORC21_RS03050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC21_RS03055	COG0745	RESPONSE REGULATOR receiver
FORC21_RS03060	COG5002	protein histidine kinase activity
FORC21_RS03070	COG4990	cell redox homeostasis
FORC21_RS03080	COG3290	protein histidine kinase activity
FORC21_RS03085	COG4565	transcriptional regulatory protein
FORC21_RS03090	COG3493	citrate carrier protein
FORC21_RS03095	COG0281	malic enzyme
FORC21_RS03105	COG0697	spore germination
FORC21_RS03110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS03120	COG5002	protein histidine kinase activity
FORC21_RS03140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC21_RS03145	COG3383	formate dehydrogenase (NAD+) activity
FORC21_RS03150	COG2427	Protein of unknown function (DUF1641)
FORC21_RS03165	COG0531	amino acid
FORC21_RS03170	COG0640	Transcriptional regulator
FORC21_RS03175	COG2217	Heavy metal translocating P-type atpase
FORC21_RS03180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC21_RS03190	COG3227	Zinc metalloprotease (Elastase)
FORC21_RS03210	COG2720	vancomycin resistance protein
FORC21_RS03215	COG1316	TRANSCRIPTIONal
FORC21_RS03220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS03225	COG0346	lactoylglutathione lyase activity
FORC21_RS03230	COG1253	flavin adenine dinucleotide binding
FORC21_RS03235	COG1027	Aspartate ammonia-lyase
FORC21_RS03240	COG1620	l-lactate permease
FORC21_RS03255	COG3104	oligopeptide transport
FORC21_RS03260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS03270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS03290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC21_RS03300	COG4548	von Willebrand factor, type A
FORC21_RS03305	COG0714	Associated with various cellular activities
FORC21_RS03330	COG0531	amino acid
FORC21_RS03335	COG2188	Transcriptional regulator
FORC21_RS03340	COG1263	PTS System
FORC21_RS03340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_RS03345	COG0366	Alpha amylase catalytic
FORC21_RS03360	COG0697	spore germination
FORC21_RS03370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC21_RS03375	COG1115	amino acid carrier protein
FORC21_RS03385	COG1126	abc transporter atp-binding protein
FORC21_RS03390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_RS03395	COG0765	amino acid transport
FORC21_RS03400	COG0765	amino acid transport
FORC21_RS03405	COG0833	amino acid
FORC21_RS03430	COG2378	regulation of single-species biofilm formation
FORC21_RS03435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC21_RS03440	COG5002	protein histidine kinase activity
FORC21_RS03465	COG0659	secondary active sulfate transmembrane transporter activity
FORC21_RS03480	COG2271	Major facilitator Superfamily
FORC21_RS03485	COG1846	Transcriptional regulator
FORC21_RS03490	COG0477	Major facilitator Superfamily
FORC21_RS03495	COG1609	Transcriptional regulator
FORC21_RS03500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC21_RS03515	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_RS03520	COG1879	ABC-type sugar transport system periplasmic component
FORC21_RS03545	COG1063	alcohol dehydrogenase
FORC21_RS03595	COG0840	transmembrane signaling receptor activity
FORC21_RS03600	COG3584	3D domain protein
FORC21_RS03600	COG1388	LysM domain
FORC21_RS03605	COG1476	TRANSCRIPTIONal
FORC21_RS03625	COG3104	oligopeptide transport
FORC21_RS03630	COG1114	Component of the transport system for branched-chain amino acids
FORC21_RS03645	COG1113	amino acid transport
FORC21_RS03650	COG2252	PERMEase
FORC21_RS03665	COG2153	protein acetylation
FORC21_RS03675	COG0569	domain protein
FORC21_RS03675	COG0475	glutathione-regulated potassium exporter activity
FORC21_RS03690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC21_RS03700	COG0833	amino acid
FORC21_RS03705	COG4990	cell redox homeostasis
FORC21_RS03720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_RS03725	COG0697	spore germination
FORC21_RS03730	COG0531	amino acid
FORC21_RS03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC21_RS03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC21_RS03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC21_RS03755	COG1918	ferrous iron import across plasma membrane
FORC21_RS03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC21_RS03765	COG0573	inorganic phosphate transmembrane transporter activity
FORC21_RS03770	COG0581	inorganic phosphate transmembrane transporter activity
FORC21_RS03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC21_RS03900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FORC21_RS03925	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC21_RS03930	COG1116	anion transmembrane transporter activity
FORC21_RS03935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_RS03940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_RS03945	COG0352	thiamine-phosphate diphosphorylase activity
FORC21_RS03950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_RS03955	COG2104	thiamine diphosphate biosynthetic process
FORC21_RS03965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_RS03970	COG0351	phosphomethylpyrimidine kinase
FORC21_RS04010	COG2205	protein histidine kinase activity
FORC21_RS04015	COG2814	Major facilitator Superfamily
FORC21_RS04020	COG1846	Transcriptional regulator
FORC21_RS04045	COG1136	(ABC) transporter
FORC21_RS04065	COG1129	ABC transporter
FORC21_RS04075	COG2252	PERMEase
FORC21_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS04095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC21_RS04100	COG1621	beta-fructofuranosidase activity
FORC21_RS04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_RS04105	COG1263	PTS System
FORC21_RS04110	COG1609	Transcriptional regulator
FORC21_RS04160	COG0778	Nitroreductase
FORC21_RS04165	COG2719	SpoVR family
FORC21_RS04175	COG1414	Transcriptional regulator
FORC21_RS04190	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC21_RS04195	COG1937	Protein conserved in bacteria
FORC21_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_RS04200	COG0425	Belongs to the sulfur carrier protein TusA family
FORC21_RS04205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_RS04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
FORC21_RS04215	COG0425	Belongs to the sulfur carrier protein TusA family
FORC21_RS04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_RS04220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_RS04230	COG0730	response to heat
FORC21_RS04240	COG1316	TRANSCRIPTIONal
FORC21_RS04245	COG0604	alcohol dehydrogenase
FORC21_RS04250	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC21_RS04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC21_RS04270	COG3711	transcriptional antiterminator
FORC21_RS04275	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC21_RS04280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC21_RS04300	COG1388	LysM domain
FORC21_RS04300	COG3584	3D domain protein
FORC21_RS04305	COG0577	efflux transmembrane transporter activity
FORC21_RS04310	COG1136	(ABC) transporter
FORC21_RS04320	COG5522	Integral membrane protein (intg_mem_TP0381)
FORC21_RS04335	COG1114	Component of the transport system for branched-chain amino acids
FORC21_RS04340	COG3546	catalase activity
FORC21_RS04375	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS04410	COG0531	amino acid
FORC21_RS04415	COG0475	glutathione-regulated potassium exporter activity
FORC21_RS04425	COG1737	Transcriptional regulator
FORC21_RS04435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_RS04435	COG1263	PTS System
FORC21_RS04445	COG2259	Doxx family
FORC21_RS04465	COG1522	sequence-specific DNA binding
FORC21_RS04470	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC21_RS04470	COG0165	Argininosuccinate lyase
FORC21_RS04475	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS04495	COG1309	transcriptional regulator
FORC21_RS04500	COG2814	Major facilitator Superfamily
FORC21_RS04505	COG1733	regulation of RNA biosynthetic process
FORC21_RS04515	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_RS04520	COG4533	DNA binding
FORC21_RS04525	COG2211	Major facilitator Superfamily
FORC21_RS04535	COG0693	protein deglycase activity
FORC21_RS04540	COG0753	catalase activity
FORC21_RS04540	COG0693	protein deglycase activity
FORC21_RS04550	COG0531	amino acid
FORC21_RS04555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC21_RS04565	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS04585	COG1132	(ABC) transporter
FORC21_RS04590	COG1132	(ABC) transporter
FORC21_RS04600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_RS04605	COG0765	amino acid transport
FORC21_RS04610	COG1126	abc transporter atp-binding protein
FORC21_RS04625	COG0189	ligase activity
FORC21_RS04645	COG4585	Histidine kinase
FORC21_RS04650	COG2197	response regulator
FORC21_RS04655	COG0028	Belongs to the TPP enzyme family
FORC21_RS04660	COG3527	Alpha-acetolactate decarboxylase
FORC21_RS04675	COG0561	phosphatase activity
FORC21_RS04685	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_RS04685	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS04690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC21_RS04700	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_RS04715	COG0659	secondary active sulfate transmembrane transporter activity
FORC21_RS04720	COG2244	polysaccharide biosynthetic process
FORC21_RS04740	COG1024	Enoyl-CoA hydratase
FORC21_RS04760	COG1363	Peptidase, m42
FORC21_RS04795	COG0601	transmembrane transport
FORC21_RS04800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_RS04805	COG0444	Belongs to the ABC transporter superfamily
FORC21_RS04810	COG4608	Belongs to the ABC transporter superfamily
FORC21_RS04820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS04840	COG0457	Tetratricopeptide repeat
FORC21_RS05075	COG0477	Major facilitator Superfamily
FORC21_RS05080	COG3290	protein histidine kinase activity
FORC21_RS05085	COG4565	transcriptional regulatory protein
FORC21_RS05090	COG3181	Tripartite tricarboxylate transporter family receptor
FORC21_RS05095	COG0494	nUDIX hydrolase
FORC21_RS05105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FORC21_RS05140	COG0305	Participates in initiation and elongation during chromosome replication
FORC21_RS05165	COG0477	Major facilitator Superfamily
FORC21_RS05180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS05190	COG3344	reverse transcriptase
FORC21_RS05210	COG1073	alpha beta
FORC21_RS05260	COG1183	phosphatidylcholine synthase activity
FORC21_RS05275	COG2376	Dihydroxyacetone kinase
FORC21_RS05285	COG2376	Dihydroxyacetone kinase
FORC21_RS05330	COG1388	LysM domain
FORC21_RS05330	COG3584	3D domain protein
FORC21_RS05335	COG0791	NLP P60 protein
FORC21_RS05335	COG1388	LysM domain
FORC21_RS05345	COG2373	Large extracellular alpha-helical protein
FORC21_RS05365	COG0596	Alpha beta hydrolase
FORC21_RS05435	COG1191	sigma factor activity
FORC21_RS05445	COG2208	phosphoserine phosphatase activity
FORC21_RS05450	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC21_RS05455	COG0784	Response regulator, receiver
FORC21_RS05455	COG5002	protein histidine kinase activity
FORC21_RS05455	COG2205	protein histidine kinase activity
FORC21_RS05500	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FORC21_RS05520	COG0420	3'-5' exonuclease activity
FORC21_RS05525	COG4717	serine-type aminopeptidase activity
FORC21_RS05535	COG0346	lactoylglutathione lyase activity
FORC21_RS05540	COG0346	lactoylglutathione lyase activity
FORC21_RS05545	COG0457	Tetratricopeptide repeat
FORC21_RS05555	COG2267	carboxylic ester hydrolase activity
FORC21_RS05580	COG2140	Oxalate decarboxylase
FORC21_RS05585	COG3620	sequence-specific DNA binding
FORC21_RS05590	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC21_RS05595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC21_RS05605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC21_RS05610	COG1695	Transcriptional regulator
FORC21_RS05625	COG1595	DNA-templated transcription, initiation
FORC21_RS05640	COG3973	AAA domain
FORC21_RS05650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC21_RS05675	COG4980	gas vesicle protein
FORC21_RS05680	COG0537	adenosine 5'-monophosphoramidase activity
FORC21_RS05690	COG1131	(ABC) transporter
FORC21_RS05695	COG4473	ABC transporter
FORC21_RS05720	COG3402	PFAM membrane-flanked domain
FORC21_RS05725	COG3428	Bacterial PH domain
FORC21_RS05755	COG0697	spore germination
FORC21_RS05760	COG3402	PFAM membrane-flanked domain
FORC21_RS05765	COG3428	Bacterial PH domain
FORC21_RS05775	COG2329	Antibiotic biosynthesis monooxygenase
FORC21_RS05780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_RS05795	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FORC21_RS05830	COG1309	transcriptional regulator
FORC21_RS05835	COG1511	domain protein
FORC21_RS05855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS05860	COG1609	Transcriptional regulator
FORC21_RS05870	COG1234	tRNA 3'-trailer cleavage
FORC21_RS05875	COG0095	Lipoate-protein ligase
FORC21_RS05885	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_RS05895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC21_RS05905	COG4208	sulfate ABC transporter
FORC21_RS06055	COG1073	alpha beta
FORC21_RS06060	COG1408	metallophosphoesterase
FORC21_RS06065	COG1078	dGTPase activity
FORC21_RS06075	COG1595	DNA-templated transcription, initiation
FORC21_RS06080	COG2207	Transcriptional regulator
FORC21_RS06080	COG3708	Transcriptional regulator
FORC21_RS06085	COG2205	protein histidine kinase activity
FORC21_RS06090	COG0745	RESPONSE REGULATOR receiver
FORC21_RS06110	COG0501	Belongs to the peptidase M48B family
FORC21_RS06115	COG0840	transmembrane signaling receptor activity
FORC21_RS06120	COG3693	PFAM glycoside hydrolase, family 10
FORC21_RS06130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC21_RS06135	COG2224	Isocitrate lyase
FORC21_RS06175	COG0398	Pfam SNARE associated Golgi protein
FORC21_RS06235	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC21_RS06260	COG0367	asparagine synthase
FORC21_RS06270	COG0753	catalase activity
FORC21_RS06275	COG0004	ammonium transporteR
FORC21_RS06300	COG2996	Protein conserved in bacteria
FORC21_RS06365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS06380	COG0561	phosphatase activity
FORC21_RS06405	COG2267	carboxylic ester hydrolase activity
FORC21_RS06425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC21_RS06430	COG5504	Zn-dependent protease
FORC21_RS06440	COG0180	Tryptophanyl-tRNA synthetase
FORC21_RS06455	COG4166	transmembrane transport
FORC21_RS06460	COG0601	transmembrane transport
FORC21_RS06465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC21_RS06470	COG0444	Belongs to the ABC transporter superfamily
FORC21_RS06475	COG4608	Belongs to the ABC transporter superfamily
FORC21_RS06480	COG0534	Mate efflux family protein
FORC21_RS06485	COG4166	transmembrane transport
FORC21_RS06505	COG0861	Integral membrane protein TerC family
FORC21_RS06525	COG1164	Oligoendopeptidase f
FORC21_RS06540	COG2346	COG2346, Truncated hemoglobins
FORC21_RS06545	COG4116	CYTH
FORC21_RS06555	COG2357	RelA SpoT domain protein
FORC21_RS06565	COG0564	pseudouridine synthase activity
FORC21_RS06580	COG0772	Belongs to the SEDS family
FORC21_RS06585	COG1216	Glycosyl transferase, family 2
FORC21_RS06605	COG0463	Glycosyl transferase, family 2
FORC21_RS06605	COG0457	Tetratricopeptide repeat
FORC21_RS06625	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC21_RS06640	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC21_RS06685	COG2153	protein acetylation
FORC21_RS06695	COG2382	esterase
FORC21_RS06720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_RS06735	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC21_RS06735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC21_RS06770	COG1620	l-lactate permease
FORC21_RS06775	COG5634	Uncharacterized conserved protein (DUF2278)
FORC21_RS06830	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC21_RS06840	COG1476	TRANSCRIPTIONal
FORC21_RS06880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_RS06895	COG4152	abc transporter atp-binding protein
FORC21_RS06900	COG1668	transmembrane transport
FORC21_RS06930	COG1686	Belongs to the peptidase S11 family
FORC21_RS06935	COG0681	Belongs to the peptidase S26 family
FORC21_RS06970	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS06980	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC21_RS06985	COG1177	transmembrane transport
FORC21_RS07000	COG2409	Drug exporters of the RND superfamily
FORC21_RS07010	COG0564	pseudouridine synthase activity
FORC21_RS07020	COG2340	Cysteine-rich secretory protein family
FORC21_RS07025	COG0247	lactate metabolic process
FORC21_RS07030	COG0277	FAD linked oxidase domain protein
FORC21_RS07035	COG3835	regulator
FORC21_RS07045	COG0745	RESPONSE REGULATOR receiver
FORC21_RS07050	COG5002	protein histidine kinase activity
FORC21_RS07055	COG2186	Transcriptional regulator
FORC21_RS07075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC21_RS07085	COG2116	formate transmembrane transporter activity
FORC21_RS07090	COG0861	Integral membrane protein TerC family
FORC21_RS07095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC21_RS07105	COG2030	dehydratase
FORC21_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS07130	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC21_RS07140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC21_RS07160	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC21_RS07165	COG3842	ATPase activity
FORC21_RS07190	COG1349	DNA-binding transcription factor activity
FORC21_RS07205	COG0235	Class ii aldolase
FORC21_RS07215	COG2861	carbohydrate metabolic process
FORC21_RS07225	COG3852	Histidine kinase
FORC21_RS07230	COG1846	Transcriptional regulator
FORC21_RS07240	COG2318	DinB family
FORC21_RS07250	COG5002	protein histidine kinase activity
FORC21_RS07260	COG0720	synthase
FORC21_RS07275	COG4873	Protein conserved in bacteria
FORC21_RS07315	COG1780	Probably involved in ribonucleotide reductase function
FORC21_RS07320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC21_RS07325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC21_RS07330	COG1725	Transcriptional regulator
FORC21_RS07335	COG1131	(ABC) transporter
FORC21_RS07345	COG1131	(ABC) transporter
FORC21_RS07365	COG1522	sequence-specific DNA binding
FORC21_RS07375	COG1335	isochorismatase
FORC21_RS07385	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC21_RS07390	COG2070	2-Nitropropane dioxygenase
FORC21_RS07395	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC21_RS07405	COG1696	Membrane protein involved in D-alanine export
FORC21_RS07430	COG0716	FMN binding
FORC21_RS07445	COG3173	Aminoglycoside phosphotransferase
FORC21_RS07490	COG1846	Transcriptional regulator
FORC21_RS07500	COG1301	dicarboxylic acid transport
FORC21_RS07505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC21_RS07510	COG4709	membrane
FORC21_RS07515	COG3874	Sporulation protein YtfJ
FORC21_RS07545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_RS07550	COG0028	Belongs to the TPP enzyme family
FORC21_RS07555	COG0440	acetolactate synthase activity
FORC21_RS07630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC21_RS07645	COG1183	phosphatidylcholine synthase activity
FORC21_RS07660	COG0019	diaminopimelate decarboxylase activity
FORC21_RS07680	COG0529	Catalyzes the synthesis of activated sulfate
FORC21_RS07685	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC21_RS07705	COG1648	precorrin-2 dehydrogenase activity
FORC21_RS07715	COG0733	neurotransmitter:sodium symporter activity
FORC21_RS07735	COG1757	Na H antiporter
FORC21_RS07750	COG4758	membrane
FORC21_RS07755	COG4585	Histidine kinase
FORC21_RS07760	COG2197	response regulator
FORC21_RS07770	COG1114	Component of the transport system for branched-chain amino acids
FORC21_RS07825	COG0730	response to heat
FORC21_RS07830	COG0306	phosphate transporter
FORC21_RS07835	COG1392	Phosphate transport regulator
FORC21_RS07840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_RS07855	COG3852	Histidine kinase
FORC21_RS07860	COG1801	Protein of unknown function DUF72
FORC21_RS07870	COG0582	viral genome integration into host DNA
FORC21_RS07875	COG5002	protein histidine kinase activity
FORC21_RS07905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC21_RS07910	COG1686	Belongs to the peptidase S11 family
FORC21_RS07915	COG2715	membrane protein required for spore maturation
FORC21_RS07920	COG0700	Nucleoside recognition
FORC21_RS07925	COG1187	pseudouridine synthase activity
FORC21_RS07935	COG1333	cytochrome c biogenesis protein
FORC21_RS07940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC21_RS07945	COG0745	RESPONSE REGULATOR receiver
FORC21_RS07950	COG5002	protein histidine kinase activity
FORC21_RS07955	COG2096	Adenosyltransferase
FORC21_RS07970	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FORC21_RS07975	COG1141	Ferredoxin
FORC21_RS07985	COG0514	ATP-dependent DNA helicase (RecQ)
FORC21_RS07990	COG1266	CAAX protease self-immunity
FORC21_RS08000	COG1408	metallophosphoesterase
FORC21_RS08005	COG0789	Transcriptional regulator
FORC21_RS08015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC21_RS08035	COG0492	ferredoxin-NADP+ reductase activity
FORC21_RS08040	COG0252	asparaginase activity
FORC21_RS08110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC21_RS08125	COG0142	geranyltranstransferase activity
FORC21_RS08135	COG0142	geranyltranstransferase activity
FORC21_RS08160	COG0457	Tetratricopeptide repeat
FORC21_RS08180	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC21_RS08185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC21_RS08185	COG2010	Cytochrome c
FORC21_RS08190	COG4347	Protein of unknown function (DUF1405)
FORC21_RS08205	COG2738	Putative neutral zinc metallopeptidase
FORC21_RS08215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS08225	COG1694	Mazg nucleotide pyrophosphohydrolase
FORC21_RS08245	COG0438	transferase activity, transferring glycosyl groups
FORC21_RS08285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC21_RS08285	COG1199	ATP-dependent helicase activity
FORC21_RS08305	COG3935	DnaD domain protein
FORC21_RS08310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC21_RS08320	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC21_RS08320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_RS08380	COG0116	Belongs to the methyltransferase superfamily
FORC21_RS08390	COG1199	ATP-dependent helicase activity
FORC21_RS08395	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC21_RS08405	COG0024	Methionine aminopeptidase
FORC21_RS08415	COG2233	PERMEase
FORC21_RS08420	COG2311	Membrane
FORC21_RS08430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC21_RS08440	COG0456	acetyltransferase
FORC21_RS08490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC21_RS08505	COG3944	biosynthesis protein
FORC21_RS08515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC21_RS08530	COG1215	transferase activity, transferring glycosyl groups
FORC21_RS08535	COG0438	transferase activity, transferring glycosyl groups
FORC21_RS08550	COG0454	-acetyltransferase
FORC21_RS08570	COG0328	RNA-DNA hybrid ribonuclease activity
FORC21_RS08605	COG3403	YqcI/YcgG family
FORC21_RS08610	COG1280	lysine exporter protein (LysE YggA)
FORC21_RS08630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_RS08635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_RS08645	COG0475	glutathione-regulated potassium exporter activity
FORC21_RS08650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC21_RS08655	COG0789	Transcriptional regulator
FORC21_RS08655	COG4978	Transcriptional regulator
FORC21_RS08665	COG2323	membrane
FORC21_RS08670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC21_RS08705	COG1923	regulation of RNA biosynthetic process
FORC21_RS08715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC21_RS08720	COG1360	Flagellar Motor Protein
FORC21_RS08725	COG2201	protein-glutamate methylesterase activity
FORC21_RS08730	COG2198	Histidine kinase
FORC21_RS08730	COG0643	Histidine kinase
FORC21_RS08735	COG1776	CheC inhibitor of MCP methylation
FORC21_RS08735	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_RS08750	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC21_RS08770	COG1256	bacterial-type flagellum assembly
FORC21_RS08775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC21_RS08795	COG1815	bacterial-type flagellum-dependent cell motility
FORC21_RS08800	COG1558	bacterial-type flagellum-dependent cell motility
FORC21_RS08810	COG1766	The M ring may be actively involved in energy transduction
FORC21_RS08815	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_RS08825	COG1157	protein secretion by the type III secretion system
FORC21_RS08845	COG1749	Flagellar hook protein flgE
FORC21_RS08860	COG0784	Response regulator, receiver
FORC21_RS08860	COG0835	chemotaxis
FORC21_RS08870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC21_RS08880	COG0741	lytic transglycosylase activity
FORC21_RS08890	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_RS08895	COG1776	CheC inhibitor of MCP methylation
FORC21_RS08895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC21_RS08905	COG1338	Plays a role in the flagellum-specific transport system
FORC21_RS08910	COG1987	bacterial-type flagellum assembly
FORC21_RS08920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC21_RS08925	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC21_RS08930	COG1419	protein localization to endoplasmic reticulum
FORC21_RS08935	COG4786	Flagellar basal body rod
FORC21_RS08940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC21_RS08975	COG2329	Antibiotic biosynthesis monooxygenase
FORC21_RS09000	COG0583	DNA-binding transcription factor activity
FORC21_RS09005	COG3842	ATPase activity
FORC21_RS09015	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC21_RS09055	COG0406	alpha-ribazole phosphatase activity
FORC21_RS09085	COG0367	asparagine synthase
FORC21_RS09115	COG1802	Transcriptional regulator
FORC21_RS09120	COG0697	spore germination
FORC21_RS09130	COG0523	cobalamin synthesis protein
FORC21_RS09135	COG0701	Predicted permease
FORC21_RS09150	COG1757	Na H antiporter
FORC21_RS09155	COG0789	Transcriptional regulator
FORC21_RS09180	COG0534	Mate efflux family protein
FORC21_RS09185	COG3340	Belongs to the peptidase S51 family
FORC21_RS09205	COG0785	Cytochrome C biogenesis protein
FORC21_RS09210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_RS09220	COG0457	Tetratricopeptide repeat
FORC21_RS09240	COG2733	membrane
FORC21_RS09280	COG1131	(ABC) transporter
FORC21_RS09295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC21_RS09300	COG0528	UMP kinase activity
FORC21_RS09320	COG1027	Aspartate ammonia-lyase
FORC21_RS09325	COG0281	malic enzyme
FORC21_RS09330	COG4191	Histidine kinase
FORC21_RS09335	COG0784	Response regulator, receiver
FORC21_RS09340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC21_RS09395	COG2814	Major facilitator Superfamily
FORC21_RS09410	COG1695	Transcriptional regulator
FORC21_RS09420	COG0477	Major facilitator Superfamily
FORC21_RS09435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC21_RS09440	COG2223	nitrite transmembrane transporter activity
FORC21_RS09445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC21_RS09465	COG0733	neurotransmitter:sodium symporter activity
FORC21_RS09475	COG5566	PFAM Mor transcription activator
FORC21_RS09480	COG2323	membrane
FORC21_RS09510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC21_RS09520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_RS09525	COG0028	Belongs to the TPP enzyme family
FORC21_RS09545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC21_RS09570	COG2814	Major facilitator Superfamily
FORC21_RS09575	COG3384	dioxygenase
FORC21_RS09585	COG3279	Response regulator of the LytR AlgR family
FORC21_RS09590	COG0427	acetyl-CoA hydrolase
FORC21_RS09610	COG4166	transmembrane transport
FORC21_RS09640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS09660	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC21_RS09675	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC21_RS09680	COG0531	amino acid
FORC21_RS09710	COG2309	aminopeptidase activity
FORC21_RS09725	COG0456	acetyltransferase
FORC21_RS09745	COG1309	transcriptional regulator
FORC21_RS09750	COG2390	Transcriptional regulator
FORC21_RS09760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS09765	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC21_RS09775	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC21_RS09785	COG0006	proline dipeptidase activity
FORC21_RS09795	COG2132	Multicopper oxidase
FORC21_RS09810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC21_RS09830	COG1114	Component of the transport system for branched-chain amino acids
FORC21_RS09840	COG1276	copper resistance
FORC21_RS09840	COG2372	response to copper ion
FORC21_RS09845	COG4549	nuclear export factor GLE1
FORC21_RS09850	COG0697	spore germination
FORC21_RS09855	COG0583	DNA-binding transcription factor activity
FORC21_RS09860	COG1959	2 iron, 2 sulfur cluster binding
FORC21_RS09865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC21_RS09870	COG0778	Nitroreductase
FORC21_RS09885	COG0628	permease
FORC21_RS09895	COG1231	oxidoreductase activity
FORC21_RS09905	COG0523	cobalamin synthesis protein
FORC21_RS09915	COG0411	ABC transporter
FORC21_RS09935	COG0583	DNA-binding transcription factor activity
FORC21_RS09965	COG1271	oxidase subunit
FORC21_RS09970	COG1294	oxidase, subunit
FORC21_RS09975	COG4988	ABC transporter
FORC21_RS09980	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC21_RS09990	COG1216	Glycosyl transferase, family 2
FORC21_RS10030	COG1686	Belongs to the peptidase S11 family
FORC21_RS10045	COG1388	LysM domain
FORC21_RS10045	COG0791	NLP P60 protein
FORC21_RS10055	COG1132	(ABC) transporter
FORC21_RS10060	COG0745	RESPONSE REGULATOR receiver
FORC21_RS10065	COG5002	protein histidine kinase activity
FORC21_RS10075	COG0300	oxidoreductase activity
FORC21_RS10105	COG0460	homoserine dehydrogenase
FORC21_RS10130	COG1316	TRANSCRIPTIONal
FORC21_RS10140	COG0745	RESPONSE REGULATOR receiver
FORC21_RS10145	COG5002	protein histidine kinase activity
FORC21_RS10160	COG1285	pathogenesis
FORC21_RS10165	COG1247	-acetyltransferase
FORC21_RS10185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC21_RS10195	COG1082	Xylose isomerase domain protein TIM barrel
FORC21_RS10205	COG2814	Major facilitator Superfamily
FORC21_RS10210	COG1279	arginine transmembrane transporter activity
FORC21_RS10215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS10225	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC21_RS10260	COG0577	efflux transmembrane transporter activity
FORC21_RS10265	COG2002	toxin-antitoxin pair type II binding
FORC21_RS10270	COG1404	Belongs to the peptidase S8 family
FORC21_RS10275	COG0640	Transcriptional regulator
FORC21_RS10280	COG0667	Aldo Keto reductase
FORC21_RS10285	COG2814	Major facilitator Superfamily
FORC21_RS10295	COG3152	Membrane
FORC21_RS10320	COG0840	transmembrane signaling receptor activity
FORC21_RS10340	COG3949	Membrane
FORC21_RS10345	COG0783	Belongs to the Dps family
FORC21_RS10360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC21_RS10370	COG1231	oxidoreductase activity
FORC21_RS10375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS10380	COG4989	oxidoreductase activity
FORC21_RS10385	COG0523	cobalamin synthesis protein
FORC21_RS10390	COG0456	acetyltransferase
FORC21_RS10395	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC21_RS10405	COG0702	epimerase
FORC21_RS10415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC21_RS10425	COG4166	transmembrane transport
FORC21_RS10450	COG5337	Spore coat protein CotH
FORC21_RS10455	COG1051	belongs to the nudix hydrolase family
FORC21_RS10460	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS10465	COG2244	polysaccharide biosynthetic process
FORC21_RS10475	COG0701	Predicted permease
FORC21_RS10480	COG3689	TIGRFAM TIGR03943 family protein
FORC21_RS10485	COG1607	acyl-coa hydrolase
FORC21_RS10495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC21_RS10510	COG0702	epimerase
FORC21_RS10515	COG2839	Protein conserved in bacteria
FORC21_RS10520	COG1253	flavin adenine dinucleotide binding
FORC21_RS10535	COG1114	Component of the transport system for branched-chain amino acids
FORC21_RS10540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC21_RS10560	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS10570	COG1876	peptidase activity
FORC21_RS10580	COG0154	amidase activity
FORC21_RS10585	COG2211	Major facilitator Superfamily
FORC21_RS10610	COG0561	phosphatase activity
FORC21_RS10625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC21_RS10640	COG1819	glycosyl
FORC21_RS10645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS10650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS10680	COG0456	acetyltransferase
FORC21_RS10715	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC21_RS10845	COG3874	Sporulation protein YtfJ
FORC21_RS10870	COG2226	methyltransferase
FORC21_RS10895	COG0346	lactoylglutathione lyase activity
FORC21_RS10905	COG0604	alcohol dehydrogenase
FORC21_RS10910	COG1595	DNA-templated transcription, initiation
FORC21_RS10920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC21_RS10930	COG0426	domain, Protein
FORC21_RS10930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC21_RS10940	COG0386	Belongs to the glutathione peroxidase family
FORC21_RS10945	COG1305	Transglutaminase-like
FORC21_RS10950	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FORC21_RS10955	COG0714	Associated with various cellular activities
FORC21_RS10960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FORC21_RS10965	COG1140	nitrate reductase beta subunit
FORC21_RS10970	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FORC21_RS10975	COG2181	nitrate reductase activity
FORC21_RS10980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_RS10985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC21_RS10990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_RS10995	COG0303	'Molybdopterin
FORC21_RS11000	COG0314	molybdopterin synthase activity
FORC21_RS11010	COG2223	nitrite transmembrane transporter activity
FORC21_RS11035	COG1648	precorrin-2 dehydrogenase activity
FORC21_RS11045	COG1587	Uroporphyrinogen-III synthase
FORC21_RS11045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC21_RS11050	COG2146	nitrite reductase [NAD(P)H] activity
FORC21_RS11055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC21_RS11060	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FORC21_RS11095	COG2359	stage V sporulation protein S
FORC21_RS11125	COG4974	Belongs to the 'phage' integrase family
FORC21_RS11150	COG0457	Tetratricopeptide repeat
FORC21_RS11170	COG1418	mRNA catabolic process
FORC21_RS11175	COG0488	(ABC) transporter
FORC21_RS11190	COG0629	single-stranded DNA binding
FORC21_RS11195	COG1413	lyase activity
FORC21_RS11210	COG2136	Putative SAM-dependent methyltransferase
FORC21_RS11210	COG2521	methyltransferase
FORC21_RS11215	COG0018	arginyl-trna synthetase
FORC21_RS11260	COG0017	Asparaginyl-tRNA synthetase
FORC21_RS11265	COG1929	Belongs to the glycerate kinase type-1 family
FORC21_RS11275	COG0745	RESPONSE REGULATOR receiver
FORC21_RS11280	COG3850	Histidine kinase
FORC21_RS11280	COG5002	protein histidine kinase activity
FORC21_RS11295	COG0733	neurotransmitter:sodium symporter activity
FORC21_RS11320	COG2610	gluconate transmembrane transporter activity
FORC21_RS11330	COG1794	racemase activity, acting on amino acids and derivatives
FORC21_RS11340	COG0456	acetyltransferase
FORC21_RS11350	COG3655	Transcriptional regulator
FORC21_RS11355	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC21_RS11365	COG1131	(ABC) transporter
FORC21_RS11370	COG4473	ABC transporter
FORC21_RS11380	COG0546	phosphoglycolate phosphatase activity
FORC21_RS11395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_RS11410	COG0768	penicillin binding
FORC21_RS11420	COG0204	Acyl-transferase
FORC21_RS11425	COG1272	protein, Hemolysin III
FORC21_RS11435	COG0805	protein transport
FORC21_RS11445	COG1307	EDD domain protein, DegV family
FORC21_RS11455	COG1999	signal sequence binding
FORC21_RS11460	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC21_RS11465	COG0367	asparagine synthase
FORC21_RS11480	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS11485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS11490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC21_RS11510	COG1335	isochorismatase
FORC21_RS11525	COG0668	transmembrane transport
FORC21_RS11530	COG4585	Histidine kinase
FORC21_RS11530	COG2203	Gaf domain
FORC21_RS11535	COG2197	response regulator
FORC21_RS11540	COG1737	Transcriptional regulator
FORC21_RS11545	COG0384	phenazine biosynthesis protein PhzF
FORC21_RS11550	COG1064	alcohol dehydrogenase
FORC21_RS11575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC21_RS11610	COG0517	IMP dehydrogenase activity
FORC21_RS11610	COG1125	glycine betaine transport
FORC21_RS11615	COG1174	glycine betaine transport
FORC21_RS11650	COG1253	flavin adenine dinucleotide binding
FORC21_RS11655	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS11660	COG5506	Protein of unknown function (DUF1694)
FORC21_RS11680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_RS11685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORC21_RS11690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FORC21_RS11695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC21_RS11700	COG0456	acetyltransferase
FORC21_RS11705	COG3829	transcription factor binding
FORC21_RS11710	COG1509	lysine 2,3-aminomutase activity
FORC21_RS11745	COG0515	serine threonine protein kinase
FORC21_RS11745	COG4991	sh3 domain protein
FORC21_RS11745	COG3064	Membrane
FORC21_RS11755	COG0671	phosphoesterase, PA-phosphatase related
FORC21_RS11760	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC21_RS11765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_RS11850	COG0300	oxidoreductase activity
FORC21_RS11870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_RS11870	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC21_RS11880	COG2814	Major facilitator Superfamily
FORC21_RS11885	COG4841	protein insertion into membrane
FORC21_RS11890	COG0372	Belongs to the citrate synthase family
FORC21_RS11895	COG2079	MmgE PrpD family protein
FORC21_RS11900	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC21_RS11905	COG1960	acyl-CoA dehydrogenase activity
FORC21_RS11910	COG2084	Dehydrogenase
FORC21_RS11920	COG1280	lysine exporter protein (LysE YggA)
FORC21_RS11925	COG1024	Enoyl-CoA hydratase
FORC21_RS11940	COG0420	3'-5' exonuclease activity
FORC21_RS11945	COG0419	ATPase involved in DNA repair
FORC21_RS11975	COG2223	nitrite transmembrane transporter activity
FORC21_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS11990	COG1169	isochorismate synthase
FORC21_RS11995	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC21_RS12000	COG1535	isochorismatase
FORC21_RS12000	COG3433	isochorismatase activity
FORC21_RS12005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC21_RS12010	COG3251	PFAM MbtH domain protein
FORC21_RS12015	COG2814	Major facilitator Superfamily
FORC21_RS12030	COG0776	regulation of translation
FORC21_RS12040	COG2318	DinB family
FORC21_RS12050	COG1115	amino acid carrier protein
FORC21_RS12070	COG1187	pseudouridine synthase activity
FORC21_RS12075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC21_RS12080	COG1136	(ABC) transporter
FORC21_RS12125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_RS12145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS12175	COG1247	-acetyltransferase
FORC21_RS12200	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FORC21_RS12210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS12240	COG0583	DNA-binding transcription factor activity
FORC21_RS12245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC21_RS12260	COG0583	DNA-binding transcription factor activity
FORC21_RS12265	COG2258	MOSC domain
FORC21_RS12280	COG1132	(ABC) transporter
FORC21_RS12285	COG1132	(ABC) transporter
FORC21_RS12315	COG1396	sequence-specific DNA binding
FORC21_RS12345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC21_RS12350	COG1595	DNA-templated transcription, initiation
FORC21_RS12380	COG1649	PFAM Uncharacterised BCR, COG1649
FORC21_RS12405	COG2971	BadF BadG BcrA BcrD
FORC21_RS12415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC21_RS12425	COG1846	Transcriptional regulator
FORC21_RS12450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS12485	COG1309	transcriptional regulator
FORC21_RS12505	COG3615	Tellurite resistance protein tehB
FORC21_RS12505	COG0500	methyltransferase
FORC21_RS12520	COG3961	Belongs to the TPP enzyme family
FORC21_RS12525	COG1846	Transcriptional regulator
FORC21_RS12560	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC21_RS12585	COG2002	toxin-antitoxin pair type II binding
FORC21_RS12595	COG0730	response to heat
FORC21_RS12600	COG0110	maltose O-acetyltransferase activity
FORC21_RS12605	COG1686	Belongs to the peptidase S11 family
FORC21_RS12620	COG2814	Major facilitator Superfamily
FORC21_RS12655	COG2312	Erythromycin esterase
FORC21_RS12665	COG0741	lytic transglycosylase activity
FORC21_RS12670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS12715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_RS12720	COG0768	penicillin binding
FORC21_RS12725	COG1595	DNA-templated transcription, initiation
FORC21_RS12735	COG0768	penicillin binding
FORC21_RS12740	COG0768	penicillin binding
FORC21_RS12750	COG1408	metallophosphoesterase
FORC21_RS12760	COG1131	(ABC) transporter
FORC21_RS12770	COG1309	transcriptional regulator
FORC21_RS12785	COG1960	acyl-CoA dehydrogenase activity
FORC21_RS12790	COG0439	Biotin carboxylase
FORC21_RS12795	COG0511	ligase activity, forming carbon-carbon bonds
FORC21_RS12800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC21_RS12805	COG1024	Enoyl-CoA hydratase
FORC21_RS12810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC21_RS12815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC21_RS12845	COG1686	Belongs to the peptidase S11 family
FORC21_RS12875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC21_RS12890	COG3227	Zinc metalloprotease (Elastase)
FORC21_RS12895	COG2207	Transcriptional regulator
FORC21_RS12925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC21_RS12935	COG2814	Major facilitator Superfamily
FORC21_RS12940	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS12945	COG1733	regulation of RNA biosynthetic process
FORC21_RS12990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS13015	COG1063	alcohol dehydrogenase
FORC21_RS13025	COG2323	membrane
FORC21_RS13030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC21_RS13040	COG3386	PFAM SMP-30 Gluconolaconase
FORC21_RS13050	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FORC21_RS13055	COG3773	Cell wall hydrolase
FORC21_RS13065	COG0745	RESPONSE REGULATOR receiver
FORC21_RS13070	COG2205	protein histidine kinase activity
FORC21_RS13080	COG0488	(ABC) transporter
FORC21_RS13090	COG1136	(ABC) transporter
FORC21_RS13095	COG0577	efflux transmembrane transporter activity
FORC21_RS13115	COG0460	homoserine dehydrogenase
FORC21_RS13120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS13130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC21_RS13190	COG2124	cytochrome p450
FORC21_RS13215	COG2124	cytochrome p450
FORC21_RS13240	COG0561	phosphatase activity
FORC21_RS13245	COG5002	protein histidine kinase activity
FORC21_RS13250	COG0768	penicillin binding
FORC21_RS13260	COG1819	glycosyl
FORC21_RS13265	COG1794	racemase activity, acting on amino acids and derivatives
FORC21_RS13290	COG2205	protein histidine kinase activity
FORC21_RS13350	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC21_RS13355	COG0604	alcohol dehydrogenase
FORC21_RS13360	COG0671	phosphoesterase, PA-phosphatase related
FORC21_RS13365	COG0768	penicillin binding
FORC21_RS13420	COG2814	Major facilitator Superfamily
FORC21_RS13440	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_RS13460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS13465	COG0697	spore germination
FORC21_RS13500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_RS13510	COG2223	nitrite transmembrane transporter activity
FORC21_RS13530	COG0592	DNA-directed DNA polymerase activity
FORC21_RS13550	COG0251	oxidation-reduction process
FORC21_RS13555	COG3878	Protein conserved in bacteria
FORC21_RS13580	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC21_RS13620	COG0322	excinuclease ABC activity
FORC21_RS13650	COG1131	(ABC) transporter
FORC21_RS13670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_RS13705	COG1011	Hydrolase
FORC21_RS13720	COG1073	alpha beta
FORC21_RS13725	COG1523	belongs to the glycosyl hydrolase 13 family
FORC21_RS13730	COG3227	Zinc metalloprotease (Elastase)
FORC21_RS13735	COG0737	Belongs to the 5'-nucleotidase family
FORC21_RS13760	COG0201	protein transport
FORC21_RS13765	COG0697	spore germination
FORC21_RS13770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS13775	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC21_RS13805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS13820	COG2959	enzyme of heme biosynthesis
FORC21_RS13860	COG1309	transcriptional regulator
FORC21_RS13890	COG3284	Transcriptional regulator
FORC21_RS13910	COG1349	DNA-binding transcription factor activity
FORC21_RS13930	COG1959	2 iron, 2 sulfur cluster binding
FORC21_RS13945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC21_RS13950	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC21_RS13955	COG0022	dehydrogenase e1 component
FORC21_RS13960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC21_RS13970	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS14005	COG4176	ABC-type proline glycine betaine transport system permease component
FORC21_RS14010	COG0517	IMP dehydrogenase activity
FORC21_RS14010	COG4175	Glycine betaine
FORC21_RS14040	COG2153	protein acetylation
FORC21_RS14045	COG3397	chitin binding
FORC21_RS14050	COG1819	glycosyl
FORC21_RS14070	COG2205	protein histidine kinase activity
FORC21_RS14075	COG2226	methyltransferase
FORC21_RS14080	COG2315	Protein conserved in bacteria
FORC21_RS14120	COG3973	AAA domain
FORC21_RS14135	COG0514	ATP-dependent DNA helicase (RecQ)
FORC21_RS14170	COG4637	Psort location Cytoplasmic, score
FORC21_RS14185	COG3397	chitin binding
FORC21_RS14200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC21_RS14205	COG1115	amino acid carrier protein
FORC21_RS14210	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS14215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC21_RS14225	COG3938	Belongs to the proline racemase family
FORC21_RS14230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC21_RS14270	COG1078	dGTPase activity
FORC21_RS14275	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS14285	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC21_RS14295	COG4166	transmembrane transport
FORC21_RS14305	COG4948	Mandelate Racemase Muconate Lactonizing
FORC21_RS14320	COG0667	Aldo Keto reductase
FORC21_RS14365	COG5002	protein histidine kinase activity
FORC21_RS14365	COG3850	Histidine kinase
FORC21_RS14370	COG0745	RESPONSE REGULATOR receiver
FORC21_RS14410	COG1164	Oligoendopeptidase f
FORC21_RS14415	COG1307	EDD domain protein, DegV family
FORC21_RS14455	COG2814	Major facilitator Superfamily
FORC21_RS14465	COG1664	Polymer-forming cytoskeletal
FORC21_RS14470	COG0789	Transcriptional regulator
FORC21_RS14475	COG4533	DNA binding
FORC21_RS14480	COG0477	Major facilitator Superfamily
FORC21_RS14480	COG2814	Major facilitator Superfamily
FORC21_RS14500	COG2261	transglycosylase associated protein
FORC21_RS14515	COG2226	methyltransferase
FORC21_RS14555	COG0436	Aminotransferase
FORC21_RS14560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC21_RS14615	COG0628	permease
FORC21_RS14630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC21_RS14635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_RS14640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_RS14680	COG2746	aminoglycoside 3-N-acetyltransferase activity
FORC21_RS14690	COG0697	spore germination
FORC21_RS14700	COG2318	DinB family
FORC21_RS14720	COG4912	Dna alkylation repair
FORC21_RS14725	COG0346	lactoylglutathione lyase activity
FORC21_RS14730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS14745	COG0861	Integral membrane protein TerC family
FORC21_RS14750	COG1368	sulfuric ester hydrolase activity
FORC21_RS14755	COG0488	(ABC) transporter
FORC21_RS14760	COG1033	growth of symbiont in host cell
FORC21_RS14760	COG2409	Drug exporters of the RND superfamily
FORC21_RS14765	COG1309	transcriptional regulator
FORC21_RS14780	COG0287	Prephenate dehydrogenase
FORC21_RS14800	COG1605	Chorismate mutase
FORC21_RS14800	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC21_RS14850	COG3584	3D domain protein
FORC21_RS14850	COG1388	LysM domain
FORC21_RS14860	COG0346	lactoylglutathione lyase activity
FORC21_RS14875	COG1309	transcriptional regulator
FORC21_RS14890	COG1879	ABC-type sugar transport system periplasmic component
FORC21_RS14895	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_RS14900	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_RS14910	COG2390	Transcriptional regulator
FORC21_RS14915	COG1070	Carbohydrate kinase
FORC21_RS14935	COG2329	Antibiotic biosynthesis monooxygenase
FORC21_RS14955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS14975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_RS14980	COG4187	Peptidase family M20/M25/M40
FORC21_RS14985	COG1414	Transcriptional regulator
FORC21_RS14995	COG0833	amino acid
FORC21_RS15010	COG3239	Fatty acid desaturase
FORC21_RS15020	COG2720	vancomycin resistance protein
FORC21_RS15025	COG1785	Belongs to the alkaline phosphatase family
FORC21_RS15035	COG3655	Transcriptional regulator
FORC21_RS15055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS15060	COG0346	lactoylglutathione lyase activity
FORC21_RS15085	COG0714	Associated with various cellular activities
FORC21_RS15110	COG0463	Glycosyl transferase, family 2
FORC21_RS15140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC21_RS15145	COG0753	catalase activity
FORC21_RS15185	COG0714	Associated with various cellular activities
FORC21_RS15310	COG0778	Nitroreductase
FORC21_RS15315	COG1846	Transcriptional regulator
FORC21_RS15340	COG4884	unkown
FORC21_RS15340	COG3831	ATPase activity
FORC21_RS15355	COG1136	(ABC) transporter
FORC21_RS15385	COG0456	acetyltransferase
FORC21_RS15400	COG0697	spore germination
FORC21_RS15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS15450	COG0730	response to heat
FORC21_RS15460	COG0833	amino acid
FORC21_RS15470	COG4335	DNA alkylation repair
FORC21_RS15510	COG0768	penicillin binding
FORC21_RS15540	COG1984	allophanate hydrolase subunit 2
FORC21_RS15545	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC21_RS15550	COG1414	Transcriptional regulator
FORC21_RS15560	COG3142	Participates in the control of copper homeostasis
FORC21_RS15565	COG0640	Transcriptional regulator
FORC21_RS15575	COG1960	acyl-CoA dehydrogenase activity
FORC21_RS15590	COG3314	Sporulation integral membrane protein YlbJ
FORC21_RS15635	COG3848	Pyruvate phosphate dikinase
FORC21_RS15635	COG0574	Belongs to the PEP-utilizing enzyme family
FORC21_RS15640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS15660	COG1063	alcohol dehydrogenase
FORC21_RS15670	COG1027	Aspartate ammonia-lyase
FORC21_RS15675	COG0252	asparaginase activity
FORC21_RS15680	COG1396	sequence-specific DNA binding
FORC21_RS15715	COG5002	protein histidine kinase activity
FORC21_RS15740	COG2207	Transcriptional regulator
FORC21_RS15760	COG0322	excinuclease ABC activity
FORC21_RS15765	COG0531	amino acid
FORC21_RS15780	COG0531	amino acid
FORC21_RS15785	COG0697	spore germination
FORC21_RS15800	COG0784	Response regulator, receiver
FORC21_RS15805	COG4191	Histidine kinase
FORC21_RS15810	COG2066	Belongs to the glutaminase family
FORC21_RS15815	COG1115	amino acid carrier protein
FORC21_RS15830	COG2124	cytochrome p450
FORC21_RS15845	COG0737	Belongs to the 5'-nucleotidase family
FORC21_RS15850	COG2267	carboxylic ester hydrolase activity
FORC21_RS15855	COG1335	isochorismatase
FORC21_RS15875	COG0583	DNA-binding transcription factor activity
FORC21_RS15880	COG1846	Transcriptional regulator
FORC21_RS15885	COG0598	Magnesium transport protein CorA
FORC21_RS15905	COG1073	alpha beta
FORC21_RS15925	COG0415	Belongs to the DNA photolyase family
FORC21_RS15940	COG0288	reversible hydration of carbon dioxide
FORC21_RS15950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC21_RS15955	COG5609	conserved protein (DUF2294)
FORC21_RS15970	COG0697	spore germination
FORC21_RS15980	COG0456	acetyltransferase
FORC21_RS15985	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC21_RS16010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS16020	COG3347	Dehydrogenase
FORC21_RS16030	COG1070	Carbohydrate kinase
FORC21_RS16035	COG0235	Class ii aldolase
FORC21_RS16045	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC21_RS16055	COG4154	Belongs to the RbsD FucU family
FORC21_RS16070	COG0798	PFAM Bile acid sodium symporter
FORC21_RS16075	COG0346	lactoylglutathione lyase activity
FORC21_RS16080	COG0640	Transcriptional regulator
FORC21_RS16095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC21_RS16100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC21_RS16100	COG3320	Male sterility
FORC21_RS16105	COG1309	transcriptional regulator
FORC21_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS16115	COG1522	sequence-specific DNA binding
FORC21_RS16140	COG0346	lactoylglutathione lyase activity
FORC21_RS16190	COG1309	transcriptional regulator
FORC21_RS16245	COG0745	RESPONSE REGULATOR receiver
FORC21_RS16250	COG5002	protein histidine kinase activity
FORC21_RS16250	COG3850	Histidine kinase
FORC21_RS16305	COG2814	Major facilitator Superfamily
FORC21_RS16330	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC21_RS16350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC21_RS16370	COG0577	efflux transmembrane transporter activity
FORC21_RS16390	COG3850	Histidine kinase
FORC21_RS16390	COG5002	protein histidine kinase activity
FORC21_RS16400	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS16425	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC21_RS16445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC21_RS16465	COG0662	Cupin 2, conserved barrel domain protein
FORC21_RS16475	COG2207	Transcriptional regulator
FORC21_RS16475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS16495	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_RS16495	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS16765	COG2849	repeat protein
FORC21_RS16770	COG5444	nuclease activity
FORC21_RS16795	COG1876	peptidase activity
FORC21_RS16800	COG2843	Capsule synthesis protein
FORC21_RS16810	COG0477	Major facilitator Superfamily
FORC21_RS16825	COG1846	Transcriptional regulator
FORC21_RS16830	COG2814	Major facilitator Superfamily
FORC21_RS16840	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC21_RS16845	COG1131	(ABC) transporter
FORC21_RS16865	COG2031	fatty acid transporter
FORC21_RS16875	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_RS16930	COG1288	antiporter activity
FORC21_RS16935	COG2356	endonuclease I
FORC21_RS16975	COG1733	regulation of RNA biosynthetic process
FORC21_RS16980	COG0778	Nitroreductase
FORC21_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS17025	COG1131	(ABC) transporter
FORC21_RS17055	COG1011	Hydrolase
FORC21_RS17065	COG2365	Tyrosine phosphatase family
FORC21_RS17100	COG0628	permease
FORC21_RS17160	COG1253	flavin adenine dinucleotide binding
FORC21_RS17165	COG0789	Transcriptional regulator
FORC21_RS17170	COG0697	spore germination
FORC21_RS17180	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC21_RS17185	COG3813	Protein conserved in bacteria
FORC21_RS17190	COG2706	6-phosphogluconolactonase activity
FORC21_RS17195	COG1070	Carbohydrate kinase
FORC21_RS17210	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC21_RS17215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC21_RS17220	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC21_RS17235	COG0604	alcohol dehydrogenase
FORC21_RS17240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC21_RS17250	COG0604	alcohol dehydrogenase
FORC21_RS17250	COG3321	synthase
FORC21_RS17260	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS17275	COG0840	transmembrane signaling receptor activity
FORC21_RS17285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_RS17285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_RS17290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC21_RS17290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC21_RS17295	COG1733	regulation of RNA biosynthetic process
FORC21_RS17310	COG0656	L-ascorbic acid biosynthetic process
FORC21_RS17315	COG2814	Major facilitator Superfamily
FORC21_RS17345	COG0814	amino acid
FORC21_RS17380	COG1733	regulation of RNA biosynthetic process
FORC21_RS17385	COG2188	Transcriptional regulator
FORC21_RS17395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC21_RS17400	COG1733	regulation of RNA biosynthetic process
FORC21_RS17405	COG1733	regulation of RNA biosynthetic process
FORC21_RS17425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS17445	COG0384	phenazine biosynthesis protein PhzF
FORC21_RS17450	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_RS17455	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_RS17460	COG1733	regulation of RNA biosynthetic process
FORC21_RS17475	COG0726	polysaccharide deacetylase
FORC21_RS17485	COG1191	sigma factor activity
FORC21_RS17570	COG1151	hydroxylamine reductase activity
FORC21_RS17600	COG2072	flavoprotein involved in K transport
FORC21_RS17640	COG1113	amino acid transport
FORC21_RS17645	COG2814	Major facilitator Superfamily
FORC21_RS17680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FORC21_RS17685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC21_RS17700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS17705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS17710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS17715	COG3739	integral membrane protein
FORC21_RS17745	COG0583	DNA-binding transcription factor activity
FORC21_RS17765	COG1193	negative regulation of DNA recombination
FORC21_RS17780	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC21_RS17785	COG1164	Oligoendopeptidase f
FORC21_RS17810	COG3781	membrane
FORC21_RS17825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC21_RS17850	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_RS17860	COG0640	Transcriptional regulator
FORC21_RS17865	COG0604	alcohol dehydrogenase
FORC21_RS17875	COG0457	Tetratricopeptide repeat
FORC21_RS17885	COG2808	Putative FMN-binding domain
FORC21_RS17890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC21_RS17905	COG0277	FAD linked oxidase domain protein
FORC21_RS17935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_RS17935	COG2198	Histidine kinase
FORC21_RS17935	COG2205	protein histidine kinase activity
FORC21_RS17935	COG0784	Response regulator, receiver
FORC21_RS17945	COG1285	pathogenesis
FORC21_RS17955	COG2514	catechol 2,3-dioxygenase activity
FORC21_RS17960	COG2720	vancomycin resistance protein
FORC21_RS18000	COG0716	FMN binding
FORC21_RS18010	COG0494	nUDIX hydrolase
FORC21_RS18030	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS18040	COG0165	Argininosuccinate lyase
FORC21_RS18055	COG4145	pantothenate transmembrane transporter activity
FORC21_RS18065	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS18080	COG1657	PFAM Prenyltransferase squalene oxidase
FORC21_RS18085	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FORC21_RS18090	COG2962	Rard protein
FORC21_RS18095	COG3326	Membrane
FORC21_RS18110	COG0489	protein tyrosine kinase activity
FORC21_RS18120	COG0314	molybdopterin synthase activity
FORC21_RS18125	COG0303	'Molybdopterin
FORC21_RS18130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_RS18135	COG2116	formate transmembrane transporter activity
FORC21_RS18150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC21_RS18155	COG5609	conserved protein (DUF2294)
FORC21_RS18160	COG2427	Protein of unknown function (DUF1641)
FORC21_RS18165	COG3383	formate dehydrogenase (NAD+) activity
FORC21_RS18175	COG0697	spore germination
FORC21_RS18190	COG0531	amino acid
FORC21_RS18225	COG2226	methyltransferase
FORC21_RS18230	COG4166	transmembrane transport
FORC21_RS18235	COG4166	transmembrane transport
FORC21_RS18240	COG4166	transmembrane transport
FORC21_RS18245	COG1301	dicarboxylic acid transport
FORC21_RS18250	COG1316	TRANSCRIPTIONal
FORC21_RS18260	COG1595	DNA-templated transcription, initiation
FORC21_RS18270	COG1131	(ABC) transporter
FORC21_RS18305	COG0673	inositol 2-dehydrogenase activity
FORC21_RS18310	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC21_RS18315	COG0187	DNA topoisomerase II activity
FORC21_RS18325	COG1832	CoA-binding protein
FORC21_RS18330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC21_RS18335	COG0745	RESPONSE REGULATOR receiver
FORC21_RS18355	COG4841	protein insertion into membrane
FORC21_RS18360	COG0824	Thioesterase
FORC21_RS18385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_RS18400	COG1132	(ABC) transporter
FORC21_RS18405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC21_RS18435	COG2211	Major facilitator Superfamily
FORC21_RS18445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC21_RS18460	COG0183	Belongs to the thiolase family
FORC21_RS18465	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_RS18470	COG1268	BioY protein
FORC21_RS18475	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_RS18480	COG1396	sequence-specific DNA binding
FORC21_RS18515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS18530	COG5002	protein histidine kinase activity
FORC21_RS18535	COG0400	carboxylic ester hydrolase activity
FORC21_RS18540	COG0346	lactoylglutathione lyase activity
FORC21_RS18545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC21_RS18555	COG0069	glutamate synthase activity
FORC21_RS18560	COG1902	pentaerythritol trinitrate reductase activity
FORC21_RS18565	COG1329	Transcriptional regulator
FORC21_RS18570	COG0010	Belongs to the arginase family
FORC21_RS18625	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC21_RS18630	COG0785	Cytochrome C biogenesis protein
FORC21_RS18645	COG1473	amidohydrolase
FORC21_RS18655	COG1131	(ABC) transporter
FORC21_RS18670	COG0583	DNA-binding transcription factor activity
FORC21_RS18680	COG1346	cytolysis
FORC21_RS18695	COG0730	response to heat
FORC21_RS18720	COG1132	(ABC) transporter
FORC21_RS18725	COG1132	(ABC) transporter
FORC21_RS18740	COG0457	Tetratricopeptide repeat
FORC21_RS18820	COG3763	UPF0154 protein
FORC21_RS18840	COG3639	organic phosphonate transmembrane transporter activity
FORC21_RS18850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_RS18855	COG0737	Belongs to the 5'-nucleotidase family
FORC21_RS18865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC21_RS18885	COG1695	Transcriptional regulator
FORC21_RS18895	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_RS18895	COG1388	LysM domain
FORC21_RS18895	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS18900	COG0739	heme binding
FORC21_RS18905	COG0741	lytic transglycosylase activity
FORC21_RS18935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC21_RS18940	COG0174	glutamine synthetase
FORC21_RS18945	COG0789	Transcriptional regulator
FORC21_RS18950	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FORC21_RS18955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC21_RS18960	COG2860	membrane
FORC21_RS18965	COG0464	growth
FORC21_RS18995	COG1388	LysM domain
FORC21_RS18995	COG3584	3D domain protein
FORC21_RS19005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC21_RS19005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC21_RS19005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC21_RS19010	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC21_RS19015	COG1349	DNA-binding transcription factor activity
FORC21_RS19020	COG1979	alcohol dehydrogenase
FORC21_RS19025	COG2322	membrane
FORC21_RS19040	COG1113	amino acid transport
FORC21_RS19055	COG1408	metallophosphoesterase
FORC21_RS19060	COG2116	formate transmembrane transporter activity
FORC21_RS19075	COG2217	Heavy metal translocating P-type atpase
FORC21_RS19080	COG2608	mercury ion transmembrane transporter activity
FORC21_RS19085	COG1937	Protein conserved in bacteria
FORC21_RS19095	COG2819	hydrolase of the alpha beta superfamily
FORC21_RS19100	COG1120	ATPase activity
FORC21_RS19105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS19110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS19115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS19125	COG0708	Exodeoxyribonuclease III
FORC21_RS19130	COG2169	Transcriptional regulator
FORC21_RS19135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC21_RS19140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC21_RS19160	COG2267	carboxylic ester hydrolase activity
FORC21_RS19165	COG3300	MHYT domain
FORC21_RS19165	COG5001	Diguanylate cyclase
FORC21_RS19185	COG1086	Polysaccharide biosynthesis protein
FORC21_RS19205	COG1346	cytolysis
FORC21_RS19215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC21_RS19225	COG2188	Transcriptional regulator
FORC21_RS19230	COG2723	6-phospho-beta-galactosidase activity
FORC21_RS19240	COG1404	Belongs to the peptidase S8 family
FORC21_RS19245	COG3773	Cell wall hydrolase
FORC21_RS19260	COG1368	sulfuric ester hydrolase activity
FORC21_RS19265	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC21_RS19290	COG4550	Control of competence regulator ComK, YlbF/YmcA
FORC21_RS19300	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC21_RS19305	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC21_RS19305	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC21_RS19315	COG2359	stage V sporulation protein S
FORC21_RS19320	COG1692	metallophosphoesterase
FORC21_RS19340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC21_RS19345	COG1426	Protein conserved in bacteria
FORC21_RS19360	COG0300	oxidoreductase activity
FORC21_RS19365	COG0612	Peptidase, M16
FORC21_RS19370	COG0612	Peptidase, M16
FORC21_RS19375	COG1079	Belongs to the binding-protein-dependent transport system permease family
FORC21_RS19380	COG4603	Belongs to the binding-protein-dependent transport system permease family
FORC21_RS19385	COG3845	ABC transporter
FORC21_RS19390	COG1744	ABC transporter substrate-binding protein PnrA-like
FORC21_RS19395	COG2188	Transcriptional regulator
FORC21_RS19415	COG0740	serine-type endopeptidase activity
FORC21_RS19420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC21_RS19430	COG0527	aspartate kinase activity
FORC21_RS19435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC21_RS19440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC21_RS19445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC21_RS19450	COG1873	PFAM PRC-barrel domain
FORC21_RS19455	COG0612	Peptidase, M16
FORC21_RS19460	COG0726	polysaccharide deacetylase
FORC21_RS19475	COG0196	riboflavin kinase activity
FORC21_RS19485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC21_RS19490	COG1550	Protein conserved in bacteria
FORC21_RS19500	COG1358	cellular component organization or biogenesis
FORC21_RS19505	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FORC21_RS19510	COG0195	Participates in both transcription termination and antitermination
FORC21_RS19530	COG0750	zinc metalloprotease
FORC21_RS19540	COG4589	Belongs to the CDS family
FORC21_RS19585	COG4974	Belongs to the 'phage' integrase family
FORC21_RS19595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC21_RS19600	COG0758	DNA mediated transformation
FORC21_RS19605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC21_RS19645	COG1837	Belongs to the UPF0109 family
FORC21_RS19655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC21_RS19665	COG0552	protein localization to endoplasmic reticulum
FORC21_RS19670	COG1196	nuclear chromosome segregation
FORC21_RS19680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC21_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS19690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC21_RS19705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC21_RS19710	COG1461	Dihydroxyacetone kinase
FORC21_RS19715	COG1302	Protein conserved in bacteria
FORC21_RS19730	COG1564	THIamine pyrophosphokinase
FORC21_RS19735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC21_RS19745	COG0515	serine threonine protein kinase
FORC21_RS19745	COG2815	serine threonine protein kinase
FORC21_RS19750	COG0631	protein serine/threonine phosphatase activity
FORC21_RS19760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC21_RS19760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC21_RS19765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC21_RS19765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC21_RS19780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC21_RS19785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC21_RS19805	COG1561	YicC-like family, N-terminal region
FORC21_RS19810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC21_RS19820	COG0006	proline dipeptidase activity
FORC21_RS19835	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC21_RS19900	COG0564	pseudouridine synthase activity
FORC21_RS19920	COG3599	regulation of cell shape
FORC21_RS19925	COG2302	S4 RNA-binding domain
FORC21_RS19930	COG0762	integral membrane protein
FORC21_RS19935	COG1799	cell septum assembly
FORC21_RS19940	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC21_RS19950	COG1873	PFAM PRC-barrel domain
FORC21_RS19955	COG1191	sigma factor activity
FORC21_RS19960	COG1191	sigma factor activity
FORC21_RS19970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC21_RS19975	COG0849	cell division
FORC21_RS19995	COG0772	Belongs to the SEDS family
FORC21_RS20015	COG0768	penicillin binding
FORC21_RS20020	COG0768	penicillin binding
FORC21_RS20040	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC21_RS20055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC21_RS20060	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC21_RS20070	COG3480	Lon protease (S16) C-terminal proteolytic domain
FORC21_RS20075	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC21_RS20080	COG3314	Sporulation integral membrane protein YlbJ
FORC21_RS20090	COG0742	ribosomal rna small subunit methyltransferase
FORC21_RS20105	COG3679	Belongs to the UPF0342 family
FORC21_RS20110	COG0406	alpha-ribazole phosphatase activity
FORC21_RS20125	COG2340	Cysteine-rich secretory protein family
FORC21_RS20140	COG3344	reverse transcriptase
FORC21_RS20150	COG3336	cytochrome c oxidase
FORC21_RS20185	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FORC21_RS20195	COG0772	Belongs to the SEDS family
FORC21_RS20205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FORC21_RS20210	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC21_RS20220	COG4896	Protein conserved in bacteria
FORC21_RS20235	COG1217	gtp-binding protein TYPA
FORC21_RS20245	COG0483	inositol monophosphate 1-phosphatase activity
FORC21_RS20265	COG1982	Orn Lys Arg decarboxylase major
FORC21_RS20315	COG0022	dehydrogenase e1 component
FORC21_RS20320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC21_RS20335	COG0561	phosphatase activity
FORC21_RS20350	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC21_RS20355	COG0569	domain protein
FORC21_RS20375	COG0583	DNA-binding transcription factor activity
FORC21_RS20380	COG0517	IMP dehydrogenase activity
FORC21_RS20390	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FORC21_RS20400	COG4703	Protein of unknown function (DUF1797)
FORC21_RS20415	COG2200	EAL domain
FORC21_RS20420	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS20425	COG1408	metallophosphoesterase
FORC21_RS20470	COG2814	Major facilitator Superfamily
FORC21_RS20490	COG3209	COG3209 Rhs family protein
FORC21_RS20505	COG2205	protein histidine kinase activity
FORC21_RS20515	COG0436	Aminotransferase
FORC21_RS20520	COG1609	Transcriptional regulator
FORC21_RS20525	COG3833	ABC-type maltose transport systems, permease component
FORC21_RS20530	COG1175	transmembrane transport
FORC21_RS20535	COG2182	Extracellular solute-binding protein
FORC21_RS20545	COG0366	Alpha amylase catalytic
FORC21_RS20550	COG3842	ATPase activity
FORC21_RS20590	COG0183	Belongs to the thiolase family
FORC21_RS20625	COG1695	Transcriptional regulator
FORC21_RS20630	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS20650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC21_RS20655	COG0436	Aminotransferase
FORC21_RS20690	COG2084	Dehydrogenase
FORC21_RS20700	COG2199	diguanylate cyclase activity
FORC21_RS20705	COG0778	Nitroreductase
FORC21_RS20730	COG1263	PTS System
FORC21_RS20730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC21_RS20730	COG2190	(PTS) system
FORC21_RS20735	COG3711	transcriptional antiterminator
FORC21_RS20745	COG2188	Transcriptional regulator
FORC21_RS20755	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC21_RS20785	COG1547	Domain of unknown function (DUF309)
FORC21_RS20790	COG0456	acetyltransferase
FORC21_RS20795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC21_RS20800	COG4086	secreted protein
FORC21_RS20805	COG0561	phosphatase activity
FORC21_RS20810	COG0697	spore germination
FORC21_RS20825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC21_RS20850	COG0733	neurotransmitter:sodium symporter activity
FORC21_RS20870	COG1686	Belongs to the peptidase S11 family
FORC21_RS20880	COG1725	Transcriptional regulator
FORC21_RS20885	COG1131	(ABC) transporter
FORC21_RS20905	COG1846	Transcriptional regulator
FORC21_RS20920	COG0598	Magnesium transport protein CorA
FORC21_RS20945	COG4974	Belongs to the 'phage' integrase family
FORC21_RS20955	COG0735	belongs to the Fur family
FORC21_RS20960	COG1300	Membrane
FORC21_RS20980	COG0667	Aldo Keto reductase
FORC21_RS20985	COG0656	L-ascorbic acid biosynthetic process
FORC21_RS20990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC21_RS20990	COG0456	acetyltransferase
FORC21_RS21000	COG0737	Belongs to the 5'-nucleotidase family
FORC21_RS21000	COG1525	nuclease
FORC21_RS21000	COG4085	toxin activity
FORC21_RS21010	COG0596	Alpha beta hydrolase
FORC21_RS21015	COG2056	Na+-H+ antiporter family
FORC21_RS21020	COG1609	Transcriptional regulator
FORC21_RS21025	COG0456	acetyltransferase
FORC21_RS21030	COG1073	alpha beta
FORC21_RS21045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_RS21045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC21_RS21050	COG0307	riboflavin synthase, alpha
FORC21_RS21080	COG2226	methyltransferase
FORC21_RS21080	COG1073	alpha beta
FORC21_RS21095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC21_RS21110	COG1757	Na H antiporter
FORC21_RS21115	COG0737	Belongs to the 5'-nucleotidase family
FORC21_RS21125	COG1522	sequence-specific DNA binding
FORC21_RS21170	COG0300	oxidoreductase activity
FORC21_RS21180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_RS21185	COG1760	l-serine dehydratase
FORC21_RS21190	COG1760	l-serine dehydratase
FORC21_RS21225	COG1285	pathogenesis
FORC21_RS21235	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC21_RS21240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS21255	COG1376	ErfK ybiS ycfS ynhG family protein
FORC21_RS21260	COG4129	membrane
FORC21_RS21265	COG1126	abc transporter atp-binding protein
FORC21_RS21270	COG0765	amino acid transport
FORC21_RS21275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC21_RS21295	COG2323	membrane
FORC21_RS21300	COG0772	Belongs to the SEDS family
FORC21_RS21310	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC21_RS21315	COG0022	dehydrogenase e1 component
FORC21_RS21320	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC21_RS21325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC21_RS21340	COG0280	phosphate acetyltransferase
FORC21_RS21350	COG3290	protein histidine kinase activity
FORC21_RS21350	COG3829	transcription factor binding
FORC21_RS21360	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_RS21365	COG3093	addiction module antidote protein HigA
FORC21_RS21385	COG0750	zinc metalloprotease
FORC21_RS21390	COG0497	DNA recombination
FORC21_RS21400	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FORC21_RS21410	COG0142	geranyltranstransferase activity
FORC21_RS21435	COG1302	Protein conserved in bacteria
FORC21_RS21440	COG0439	Biotin carboxylase
FORC21_RS21445	COG0511	ligase activity, forming carbon-carbon bonds
FORC21_RS21490	COG3854	ATPases associated with a variety of cellular activities
FORC21_RS21515	COG0006	proline dipeptidase activity
FORC21_RS21530	COG3872	metal-dependent enzyme
FORC21_RS21540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC21_RS21575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_RS21585	COG1609	Transcriptional regulator
FORC21_RS21595	COG2076	Multidrug Resistance protein
FORC21_RS21600	COG2076	Multidrug Resistance protein
FORC21_RS21640	COG1131	(ABC) transporter
FORC21_RS21645	COG1725	Transcriptional regulator
FORC21_RS21680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC21_RS21725	COG2169	Transcriptional regulator
FORC21_RS21730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC21_RS21760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC21_RS21765	COG2169	Transcriptional regulator
FORC21_RS21790	COG2264	protein methyltransferase activity
FORC21_RS21840	COG1459	type II secretion system
FORC21_RS21845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC21_RS21900	COG1410	methionine synthase
FORC21_RS21900	COG0646	methionine synthase
FORC21_RS21905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC21_RS21905	COG0646	methionine synthase
FORC21_RS21910	COG0626	cystathionine gamma-synthase activity
FORC21_RS21915	COG0626	cystathionine gamma-synthase activity
FORC21_RS21935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS21945	COG1940	carbohydrate kinase activity
FORC21_RS21950	COG4483	Protein conserved in bacteria
FORC21_RS21955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC21_RS21960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC21_RS21965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC21_RS21970	COG0704	Plays a role in the regulation of phosphate uptake
FORC21_RS21980	COG0573	inorganic phosphate transmembrane transporter activity
FORC21_RS21985	COG0573	inorganic phosphate transmembrane transporter activity
FORC21_RS21990	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC21_RS21995	COG0768	penicillin binding
FORC21_RS22000	COG0477	Major facilitator Superfamily
FORC21_RS22005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC21_RS22015	COG5521	maltodextrose utilization protein MalA
FORC21_RS22030	COG0735	belongs to the Fur family
FORC21_RS22035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC21_RS22040	COG1121	(ABC) transporter
FORC21_RS22045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS22075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC21_RS22080	COG2384	SAM-dependent methyltransferase
FORC21_RS22090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC21_RS22095	COG0358	DNA primase activity
FORC21_RS22115	COG0517	IMP dehydrogenase activity
FORC21_RS22130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC21_RS22135	COG0295	cytidine deaminase activity
FORC21_RS22140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC21_RS22150	COG1480	7TM receptor with intracellular HD hydrolase
FORC21_RS22155	COG1702	phosphate starvation-inducible protein PhoH
FORC21_RS22175	COG1610	YqeY-like protein
FORC21_RS22180	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC21_RS22190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC21_RS22195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC21_RS22225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC21_RS22230	COG1733	regulation of RNA biosynthetic process
FORC21_RS22255	COG1466	dna polymerase III delta subunit
FORC21_RS22265	COG0658	competence protein
FORC21_RS22265	COG2333	competence protein COMEC
FORC21_RS22270	COG2131	deaminase
FORC21_RS22275	COG1596	polysaccharide export
FORC21_RS22275	COG1555	photosystem II stabilization
FORC21_RS22280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC21_RS22285	COG2226	methyltransferase
FORC21_RS22290	COG0799	negative regulation of ribosome biogenesis
FORC21_RS22295	COG1713	HD superfamily hydrolase involved in NAD metabolism
FORC21_RS22305	COG1534	Rna-binding protein
FORC21_RS22315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC21_RS22320	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FORC21_RS22355	COG0778	Nitroreductase
FORC21_RS22360	COG2357	RelA SpoT domain protein
FORC21_RS22370	COG1785	Belongs to the alkaline phosphatase family
FORC21_RS22380	COG2267	carboxylic ester hydrolase activity
FORC21_RS22415	COG1404	Belongs to the peptidase S8 family
FORC21_RS22420	COG3186	Phenylalanine-4-hydroxylase
FORC21_RS22430	COG2514	catechol 2,3-dioxygenase activity
FORC21_RS22435	COG2259	Doxx family
FORC21_RS22475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS22490	COG1454	alcohol dehydrogenase
FORC21_RS22490	COG1012	belongs to the aldehyde dehydrogenase family
FORC21_RS22495	COG0626	cystathionine gamma-synthase activity
FORC21_RS22500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC21_RS22525	COG0768	penicillin binding
FORC21_RS22545	COG0826	peptidase U32
FORC21_RS22550	COG0826	peptidase U32
FORC21_RS22555	COG4122	O-methyltransferase activity
FORC21_RS22560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC21_RS22590	COG0628	permease
FORC21_RS22610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC21_RS22625	COG1104	cysteine desulfurase activity
FORC21_RS22630	COG1959	2 iron, 2 sulfur cluster binding
FORC21_RS22635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC21_RS22650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC21_RS22675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC21_RS22685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC21_RS22685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FORC21_RS22690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC21_RS22695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC21_RS22695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC21_RS22705	COG2244	polysaccharide biosynthetic process
FORC21_RS22710	COG2323	membrane
FORC21_RS22720	COG1862	Preprotein translocase
FORC21_RS22750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC21_RS22780	COG0157	Belongs to the NadC ModD family
FORC21_RS22785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC21_RS22790	COG1104	cysteine desulfurase activity
FORC21_RS22795	COG1827	regulation of RNA biosynthetic process
FORC21_RS22800	COG2258	MOSC domain
FORC21_RS22805	COG0077	Prephenate dehydratase
FORC21_RS22810	COG0577	efflux transmembrane transporter activity
FORC21_RS22815	COG0577	efflux transmembrane transporter activity
FORC21_RS22820	COG1136	(ABC) transporter
FORC21_RS22825	COG5002	protein histidine kinase activity
FORC21_RS22830	COG0745	RESPONSE REGULATOR receiver
FORC21_RS22840	COG3290	protein histidine kinase activity
FORC21_RS22850	COG2868	ribosomal protein
FORC21_RS22860	COG1530	ribonuclease E activity
FORC21_RS22865	COG1994	Peptidase M50
FORC21_RS22870	COG0739	heme binding
FORC21_RS22875	COG2894	cell division
FORC21_RS22895	COG1077	Cell shape determining protein MreB Mrl
FORC21_RS22915	COG0285	dihydrofolate synthase activity
FORC21_RS22930	COG1388	LysM domain
FORC21_RS22940	COG0113	porphobilinogen synthase activity
FORC21_RS22945	COG1587	Uroporphyrinogen-III synthase
FORC21_RS22955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC21_RS22985	COG0470	DNA polymerase III
FORC21_RS22985	COG1067	ATP-dependent peptidase activity
FORC21_RS23035	COG0622	Phosphoesterase
FORC21_RS23050	COG5401	PFAM Sporulation and spore germination
FORC21_RS23070	COG1309	transcriptional regulator
FORC21_RS23080	COG2197	response regulator
FORC21_RS23205	COG3621	Patatin-like phospholipase
FORC21_RS23220	COG2197	response regulator
FORC21_RS23225	COG2233	PERMEase
FORC21_RS23230	COG0402	S-adenosylhomocysteine deaminase activity
FORC21_RS23235	COG1983	PspC domain protein
FORC21_RS23240	COG1396	sequence-specific DNA binding
FORC21_RS23245	COG0697	spore germination
FORC21_RS23255	COG1959	2 iron, 2 sulfur cluster binding
FORC21_RS23260	COG1668	transmembrane transport
FORC21_RS23265	COG4152	abc transporter atp-binding protein
FORC21_RS23270	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FORC21_RS23275	COG1360	Flagellar Motor Protein
FORC21_RS23280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC21_RS23285	COG1876	peptidase activity
FORC21_RS23290	COG0824	Thioesterase
FORC21_RS23295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC21_RS23300	COG1053	succinate dehydrogenase
FORC21_RS23305	COG2009	succinate dehydrogenase
FORC21_RS23310	COG1719	4-vinyl reductase, 4VR
FORC21_RS23320	COG3118	belongs to the thioredoxin family
FORC21_RS23325	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FORC21_RS23330	COG2086	electron transfer activity
FORC21_RS23335	COG1024	Enoyl-CoA hydratase
FORC21_RS23340	COG1309	transcriptional regulator
FORC21_RS23345	COG0318	PFAM AMP-dependent synthetase and ligase
FORC21_RS23375	COG2318	DinB family
FORC21_RS23400	COG1131	(ABC) transporter
FORC21_RS23405	COG2205	protein histidine kinase activity
FORC21_RS23410	COG0745	RESPONSE REGULATOR receiver
FORC21_RS23420	COG4895	conserved protein (DUF2196)
FORC21_RS23425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC21_RS23440	COG4509	Sortase family
FORC21_RS23445	COG1120	ATPase activity
FORC21_RS23460	COG5386	Cell surface protein
FORC21_RS23470	COG5386	Cell surface protein
FORC21_RS23475	COG1114	Component of the transport system for branched-chain amino acids
FORC21_RS23480	COG1187	pseudouridine synthase activity
FORC21_RS23495	COG1796	DNA polymerase
FORC21_RS23495	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC21_RS23500	COG1286	toxin biosynthetic process
FORC21_RS23540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC21_RS23550	COG1418	mRNA catabolic process
FORC21_RS23560	COG2814	Major facilitator Superfamily
FORC21_RS23565	COG1566	PFAM secretion protein HlyD family protein
FORC21_RS23570	COG1309	transcriptional regulator
FORC21_RS23575	COG1363	Peptidase, m42
FORC21_RS23600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC21_RS23615	COG1484	DNA-dependent DNA replication
FORC21_RS23620	COG3611	Membrane attachment protein
FORC21_RS23630	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC21_RS23640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC21_RS23650	COG1971	Probably functions as a manganese efflux pump
FORC21_RS23660	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC21_RS23660	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC21_RS23665	COG5002	protein histidine kinase activity
FORC21_RS23670	COG0745	RESPONSE REGULATOR receiver
FORC21_RS23695	COG0538	isocitrate dehydrogenase activity
FORC21_RS23700	COG0372	Belongs to the citrate synthase family
FORC21_RS23715	COG0628	permease
FORC21_RS23720	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC21_RS23745	COG1725	Transcriptional regulator
FORC21_RS23750	COG0281	malic enzyme
FORC21_RS23755	COG0587	DNA-directed DNA polymerase activity
FORC21_RS23770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC21_RS23785	COG4109	DRTGG domain
FORC21_RS23800	COG0006	proline dipeptidase activity
FORC21_RS23835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS23840	COG0662	Cupin 2, conserved barrel domain protein
FORC21_RS23855	COG1028	Short-chain dehydrogenase reductase Sdr
FORC21_RS23860	COG0589	response to stress
FORC21_RS23910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS23935	COG0827	DNA restriction-modification system
FORC21_RS23940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC21_RS23950	COG3874	Sporulation protein YtfJ
FORC21_RS23965	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FORC21_RS23975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC21_RS23990	COG1104	cysteine desulfurase activity
FORC21_RS24000	COG0583	DNA-binding transcription factor activity
FORC21_RS24005	COG0697	spore germination
FORC21_RS24010	COG1309	transcriptional regulator
FORC21_RS24015	COG1956	GAF domain-containing protein
FORC21_RS24020	COG0626	cystathionine gamma-synthase activity
FORC21_RS24060	COG0110	maltose O-acetyltransferase activity
FORC21_RS24065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC21_RS24070	COG0454	-acetyltransferase
FORC21_RS24075	COG0517	IMP dehydrogenase activity
FORC21_RS24080	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC21_RS24095	COG0745	RESPONSE REGULATOR receiver
FORC21_RS24105	COG0666	response to abiotic stimulus
FORC21_RS24140	COG1609	Transcriptional regulator
FORC21_RS24155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC21_RS24155	COG1605	Chorismate mutase
FORC21_RS24160	COG4851	CamS sex pheromone cAM373 precursor
FORC21_RS24165	COG3118	belongs to the thioredoxin family
FORC21_RS24175	COG2309	aminopeptidase activity
FORC21_RS24200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS24215	COG1674	ftsk spoiiie
FORC21_RS24220	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC21_RS24220	COG1388	LysM domain
FORC21_RS24235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC21_RS24245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_RS24250	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC21_RS24255	COG1363	Peptidase, m42
FORC21_RS24265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS24280	COG0510	thiamine kinase activity
FORC21_RS24285	COG1523	belongs to the glycosyl hydrolase 13 family
FORC21_RS24300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC21_RS24305	COG1349	DNA-binding transcription factor activity
FORC21_RS24310	COG1187	pseudouridine synthase activity
FORC21_RS24315	COG2244	polysaccharide biosynthetic process
FORC21_RS24320	COG2081	HI0933 family
FORC21_RS24330	COG2814	Major facilitator Superfamily
FORC21_RS24340	COG3832	glyoxalase III activity
FORC21_RS24365	COG1329	Transcriptional regulator
FORC21_RS24390	COG0314	molybdopterin synthase activity
FORC21_RS24395	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC21_RS24400	COG0303	'Molybdopterin
FORC21_RS24410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC21_RS24415	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC21_RS24440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC21_RS24450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC21_RS24490	COG2814	Major facilitator Superfamily
FORC21_RS24495	COG0475	glutathione-regulated potassium exporter activity
FORC21_RS24500	COG0490	domain, Protein
FORC21_RS24505	COG0582	viral genome integration into host DNA
FORC21_RS24515	COG1136	(ABC) transporter
FORC21_RS24535	COG1242	4 iron, 4 sulfur cluster binding
FORC21_RS24540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FORC21_RS24555	COG1794	racemase activity, acting on amino acids and derivatives
FORC21_RS24570	COG2267	carboxylic ester hydrolase activity
FORC21_RS24575	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC21_RS24580	COG0671	phosphoesterase, PA-phosphatase related
FORC21_RS24585	COG0438	transferase activity, transferring glycosyl groups
FORC21_RS24605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS24665	COG5002	protein histidine kinase activity
FORC21_RS24670	COG3852	Histidine kinase
FORC21_RS24680	COG2267	carboxylic ester hydrolase activity
FORC21_RS24685	COG1368	sulfuric ester hydrolase activity
FORC21_RS24700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC21_RS24705	COG1116	anion transmembrane transporter activity
FORC21_RS24710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC21_RS24735	COG0494	nUDIX hydrolase
FORC21_RS24770	COG1854	S-ribosylhomocysteine lyase activity
FORC21_RS24780	COG0288	reversible hydration of carbon dioxide
FORC21_RS24785	COG1271	oxidase subunit
FORC21_RS24790	COG1294	oxidase, subunit
FORC21_RS24805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS24830	COG1842	Phage shock protein A
FORC21_RS24860	COG5002	protein histidine kinase activity
FORC21_RS24865	COG0745	RESPONSE REGULATOR receiver
FORC21_RS24890	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC21_RS24895	COG1597	lipid kinase activity
FORC21_RS24935	COG0577	efflux transmembrane transporter activity
FORC21_RS24940	COG1136	(ABC) transporter
FORC21_RS24955	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS24965	COG0577	efflux transmembrane transporter activity
FORC21_RS24970	COG1136	(ABC) transporter
FORC21_RS24975	COG3708	Transcriptional regulator
FORC21_RS24975	COG2207	Transcriptional regulator
FORC21_RS24980	COG5658	integral membrane protein
FORC21_RS24985	COG0640	Transcriptional regulator
FORC21_RS24990	COG0745	RESPONSE REGULATOR receiver
FORC21_RS24995	COG2205	protein histidine kinase activity
FORC21_RS25000	COG0577	efflux transmembrane transporter activity
FORC21_RS25005	COG0577	efflux transmembrane transporter activity
FORC21_RS25010	COG1136	(ABC) transporter
FORC21_RS25015	COG0577	efflux transmembrane transporter activity
FORC21_RS25040	COG2188	Transcriptional regulator
FORC21_RS25060	COG3964	amidohydrolase
FORC21_RS25085	COG4948	Mandelate Racemase Muconate Lactonizing
FORC21_RS25095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC21_RS25100	COG0596	Alpha beta hydrolase
FORC21_RS25110	COG1169	isochorismate synthase
FORC21_RS25115	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC21_RS25120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC21_RS25150	COG0058	SHG alpha-glucan phosphorylase activity
FORC21_RS25160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC21_RS25180	COG1404	Belongs to the peptidase S8 family
FORC21_RS25285	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC21_RS25325	COG1285	pathogenesis
FORC21_RS25330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC21_RS25350	COG2155	Conserved Protein
FORC21_RS25355	COG1098	S1 RNA binding domain
FORC21_RS25360	COG0436	Aminotransferase
FORC21_RS25365	COG1522	sequence-specific DNA binding
FORC21_RS25370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC21_RS25375	COG2267	carboxylic ester hydrolase activity
FORC21_RS25385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC21_RS25405	COG5018	Exonuclease
FORC21_RS25410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC21_RS25435	COG2050	protein possibly involved in aromatic compounds catabolism
FORC21_RS25445	COG1268	BioY protein
FORC21_RS25450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC21_RS25455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC21_RS25475	COG2076	Multidrug Resistance protein
FORC21_RS25480	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC21_RS25490	COG3584	3D domain protein
FORC21_RS25505	COG1252	NADH dehydrogenase
FORC21_RS25520	COG3708	Transcriptional regulator
FORC21_RS25535	COG1683	Conserved Protein
FORC21_RS25555	COG0316	Belongs to the HesB IscA family
FORC21_RS25570	COG1252	NADH dehydrogenase
FORC21_RS25585	COG0390	transport system, permease component
FORC21_RS25590	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC21_RS25630	COG4837	Protein of unknown function (DUF1462)
FORC21_RS25635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC21_RS25645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC21_RS25650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC21_RS25665	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC21_RS25675	COG0647	UMP catabolic process
FORC21_RS25685	COG2445	Protein of unknown function DUF86
FORC21_RS25690	COG1494	fructose-1,6-bisphosphatase
FORC21_RS25710	COG4470	Protein conserved in bacteria
FORC21_RS25720	COG0789	Transcriptional regulator
FORC21_RS25725	COG4377	Putative membrane peptidase family (DUF2324)
FORC21_RS25750	COG0739	heme binding
FORC21_RS25760	COG3377	Domain of unknown function (DUF1805)
FORC21_RS25765	COG0737	Belongs to the 5'-nucleotidase family
FORC21_RS25770	COG0719	Fe-S assembly protein
FORC21_RS25775	COG0822	iron-sulfur transferase activity
FORC21_RS25780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC21_RS25785	COG0719	Fe-S assembly protein
FORC21_RS25790	COG0396	ATPase activity
FORC21_RS25795	COG1464	Belongs to the NlpA lipoprotein family
FORC21_RS25800	COG1464	Belongs to the NlpA lipoprotein family
FORC21_RS25805	COG2011	ABC-type metal ion transport system permease component
FORC21_RS25820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC21_RS25825	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FORC21_RS25885	COG1309	transcriptional regulator
FORC21_RS25890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC21_RS25895	COG1960	acyl-CoA dehydrogenase activity
FORC21_RS25900	COG0183	Belongs to the thiolase family
FORC21_RS25905	COG1024	Enoyl-CoA hydratase
FORC21_RS25905	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC21_RS25915	COG1686	Belongs to the peptidase S11 family
FORC21_RS25930	COG0011	TIGRFAM Protein of
FORC21_RS25935	COG0840	transmembrane signaling receptor activity
FORC21_RS25950	COG2814	Major facilitator Superfamily
FORC21_RS25955	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FORC21_RS25965	COG0531	amino acid
FORC21_RS26000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC21_RS26045	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS26055	COG1376	ErfK ybiS ycfS ynhG family protein
FORC21_RS26060	COG0745	RESPONSE REGULATOR receiver
FORC21_RS26065	COG5002	protein histidine kinase activity
FORC21_RS26105	COG0840	transmembrane signaling receptor activity
FORC21_RS26110	COG2151	metal-sulfur cluster biosynthetic enzyme
FORC21_RS26115	COG3227	Zinc metalloprotease (Elastase)
FORC21_RS26120	COG1741	Belongs to the pirin family
FORC21_RS26135	COG0586	Pfam SNARE associated Golgi protein
FORC21_RS26140	COG0475	glutathione-regulated potassium exporter activity
FORC21_RS26145	COG0490	domain, Protein
FORC21_RS26155	COG1115	amino acid carrier protein
FORC21_RS26170	COG0783	Belongs to the Dps family
FORC21_RS26190	COG1611	Belongs to the LOG family
FORC21_RS26200	COG1528	Iron-storage protein
FORC21_RS26210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS26215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS26220	COG1115	amino acid carrier protein
FORC21_RS26225	COG1115	amino acid carrier protein
FORC21_RS26230	COG2910	NAD(P)H-binding
FORC21_RS26250	COG0656	L-ascorbic acid biosynthetic process
FORC21_RS26255	COG2814	Major facilitator Superfamily
FORC21_RS26260	COG1733	regulation of RNA biosynthetic process
FORC21_RS26270	COG1252	NADH dehydrogenase
FORC21_RS26275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC21_RS26325	COG0488	(ABC) transporter
FORC21_RS26330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC21_RS26415	COG0557	exoribonuclease II activity
FORC21_RS26420	COG1647	Serine aminopeptidase, S33
FORC21_RS26425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC21_RS26430	COG1346	cytolysis
FORC21_RS26465	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC21_RS26480	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC21_RS26490	COG1668	transmembrane transport
FORC21_RS26495	COG4152	abc transporter atp-binding protein
FORC21_RS26500	COG4585	Histidine kinase
FORC21_RS26530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC21_RS26545	COG2323	membrane
FORC21_RS26555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC21_RS26565	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC21_RS26575	COG1051	belongs to the nudix hydrolase family
FORC21_RS26585	COG0492	ferredoxin-NADP+ reductase activity
FORC21_RS26590	COG0457	Tetratricopeptide repeat
FORC21_RS26595	COG0110	maltose O-acetyltransferase activity
FORC21_RS26615	COG1950	PFAM Membrane protein of
FORC21_RS26620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC21_RS26625	COG0556	nucleotide-excision repair
FORC21_RS26640	COG0789	Transcriptional regulator
FORC21_RS26660	COG0583	DNA-binding transcription factor activity
FORC21_RS26670	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC21_RS26675	COG0488	(ABC) transporter
FORC21_RS26685	COG1132	(ABC) transporter
FORC21_RS26695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC21_RS26700	COG0793	Belongs to the peptidase S41A family
FORC21_RS26700	COG3409	Peptidoglycan-binding domain 1 protein
FORC21_RS26705	COG2177	Part of the ABC transporter FtsEX involved in
FORC21_RS26710	COG2884	Cell division ATP-binding protein ftsE
FORC21_RS26730	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC21_RS26750	COG1131	(ABC) transporter
FORC21_RS26780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC21_RS26785	COG1278	Cold shock
FORC21_RS26790	COG1040	competence protein
FORC21_RS26795	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FORC21_RS26800	COG0791	NLP P60 protein
FORC21_RS26805	COG1733	regulation of RNA biosynthetic process
FORC21_RS26815	COG1307	EDD domain protein, DegV family
FORC21_RS26820	COG1739	Uncharacterized protein family UPF0029
FORC21_RS26825	COG1316	TRANSCRIPTIONal
FORC21_RS26830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC21_RS26835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC21_RS26840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC21_RS26850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC21_RS26850	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FORC21_RS26870	COG1486	melibiose metabolic process
FORC21_RS26875	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC21_RS26880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC21_RS26900	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC21_RS26910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC21_RS26915	COG1301	dicarboxylic acid transport
FORC21_RS26950	COG1511	domain protein
FORC21_RS26955	COG0583	DNA-binding transcription factor activity
FORC21_RS26960	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC21_RS26970	COG1271	oxidase subunit
FORC21_RS26975	COG1294	oxidase, subunit
FORC21_RS26980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC21_RS26990	COG1620	l-lactate permease
FORC21_RS27000	COG2389	metal-binding protein
FORC21_RS27015	COG1368	sulfuric ester hydrolase activity
FORC21_RS27030	COG1388	LysM domain
FORC21_RS27030	COG0791	NLP P60 protein
FORC21_RS27035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC21_RS27045	COG1215	transferase activity, transferring glycosyl groups
FORC21_RS27055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC21_RS27065	COG3584	3D domain protein
FORC21_RS27065	COG1388	LysM domain
FORC21_RS27090	COG4715	Zinc finger, swim domain protein
FORC21_RS27095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC21_RS27135	COG0577	efflux transmembrane transporter activity
FORC21_RS27140	COG1136	(ABC) transporter
FORC21_RS27165	COG5002	protein histidine kinase activity
FORC21_RS27170	COG0745	RESPONSE REGULATOR receiver
FORC21_RS27175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC21_RS27190	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC21_RS27205	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC21_RS27210	COG0438	transferase activity, transferring glycosyl groups
FORC21_RS27220	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FORC21_RS27225	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC21_RS27240	COG1215	transferase activity, transferring glycosyl groups
FORC21_RS27245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC21_RS27250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC21_RS27255	COG4464	protein tyrosine phosphatase activity
FORC21_RS27260	COG0489	protein tyrosine kinase activity
FORC21_RS27265	COG3944	biosynthesis protein
FORC21_RS27270	COG0489	protein tyrosine kinase activity
FORC21_RS27285	COG1609	Transcriptional regulator
FORC21_RS27295	COG0739	heme binding
FORC21_RS27310	COG4555	ABC transporter
FORC21_RS27315	COG2385	sporulation resulting in formation of a cellular spore
FORC21_RS27330	COG4836	Membrane
FORC21_RS27335	COG1007	ATP synthesis coupled electron transport
FORC21_RS27340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC21_RS27345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC21_RS27355	COG0839	Belongs to the complex I subunit 6 family
FORC21_RS27375	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC21_RS27390	COG5001	Diguanylate cyclase
FORC21_RS27390	COG3300	MHYT domain
FORC21_RS27440	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC21_RS27475	COG0698	ribose 5-phosphate isomerase
FORC21_RS27495	COG2259	Doxx family
FORC21_RS27500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC21_RS27515	COG0009	L-threonylcarbamoyladenylate synthase
FORC21_RS27555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC21_RS27560	COG1494	fructose-1,6-bisphosphatase
FORC21_RS27585	COG4821	SIS domain
FORC21_RS27605	COG1960	acyl-CoA dehydrogenase activity
FORC21_RS27610	COG1960	acyl-CoA dehydrogenase activity
FORC21_RS27615	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC21_RS27620	COG0183	Belongs to the thiolase family
FORC21_RS27625	COG0247	lactate metabolic process
FORC21_RS27625	COG2181	nitrate reductase activity
FORC21_RS27630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC21_RS27640	COG5001	Diguanylate cyclase
FORC21_RS27640	COG3300	MHYT domain
FORC21_RS27655	COG3227	Zinc metalloprotease (Elastase)
FORC21_RS27660	COG2197	response regulator
FORC21_RS27665	COG4585	Histidine kinase
FORC21_RS27670	COG0842	Transport permease protein
FORC21_RS27675	COG1131	(ABC) transporter
FORC21_RS27680	COG0024	Methionine aminopeptidase
FORC21_RS27690	COG2234	aminopeptidase activity
FORC21_RS27710	COG1595	DNA-templated transcription, initiation
FORC21_RS27725	COG4506	Protein conserved in bacteria
FORC21_RS27730	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC21_RS27765	COG2814	Major facilitator Superfamily
FORC21_RS27770	COG0789	Transcriptional regulator
FORC21_RS27775	COG0584	glycerophosphoryl diester phosphodiesterase
FORC21_RS27780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC21_RS27790	COG1994	Peptidase M50
FORC21_RS27800	COG1078	dGTPase activity
FORC21_RS27805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC21_RS27810	COG1120	ATPase activity
FORC21_RS27815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS27820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC21_RS27840	COG0280	phosphate acetyltransferase
FORC21_RS27855	COG3773	Cell wall hydrolase
FORC21_RS27865	COG2363	Small membrane protein
FORC21_RS27875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC21_RS27880	COG2233	PERMEase
FORC21_RS27885	COG0561	phosphatase activity
FORC21_RS27890	COG2814	Major facilitator Superfamily
FORC21_RS27900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC21_RS27905	COG1131	(ABC) transporter
FORC21_RS27910	COG2755	lipolytic protein G-D-S-L family
FORC21_RS27915	COG1609	Transcriptional regulator
FORC21_RS27925	COG0460	homoserine dehydrogenase
FORC21_RS27935	COG2873	o-acetylhomoserine
FORC21_RS27945	COG1011	Hydrolase
FORC21_RS27950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC21_RS27965	COG2203	Gaf domain
FORC21_RS27965	COG4585	Histidine kinase
FORC21_RS27970	COG0351	phosphomethylpyrimidine kinase
FORC21_RS27975	COG3706	GGDEF domain
FORC21_RS27980	COG2879	small protein
FORC21_RS27985	COG1966	Carbon starvation protein
FORC21_RS27990	COG3279	Response regulator of the LytR AlgR family
FORC21_RS27995	COG0477	Major facilitator Superfamily
FORC21_RS28010	COG0438	transferase activity, transferring glycosyl groups
FORC21_RS28025	COG0840	transmembrane signaling receptor activity
FORC21_RS28035	COG1607	acyl-coa hydrolase
FORC21_RS28040	COG1216	Glycosyl transferase, family 2
FORC21_RS28050	COG1216	Glycosyl transferase, family 2
FORC21_RS28060	COG4485	Bacterial membrane protein, YfhO
FORC21_RS28065	COG0463	Glycosyl transferase, family 2
FORC21_RS28070	COG0488	(ABC) transporter
FORC21_RS28075	COG1309	transcriptional regulator
FORC21_RS28080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC21_RS28085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC21_RS28085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC21_RS28090	COG0628	permease
FORC21_RS28110	COG3275	phosphorelay sensor kinase activity
FORC21_RS28115	COG2814	Major facilitator Superfamily
FORC21_RS28120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC21_RS28125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FORC21_RS28155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC21_RS28160	COG1272	protein, Hemolysin III
FORC21_RS28180	COG1164	Oligoendopeptidase f
FORC21_RS28190	COG5002	protein histidine kinase activity
FORC21_RS28205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC21_RS28210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC21_RS28215	COG4853	Protein conserved in bacteria
FORC21_RS28225	COG5002	protein histidine kinase activity
FORC21_RS28230	COG0745	RESPONSE REGULATOR receiver
FORC21_RS28260	COG0305	Participates in initiation and elongation during chromosome replication
FORC21_RS28270	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FORC21_RS28275	COG4241	membrane
FORC21_RS28295	COG0012	GTP binding
FORC21_RS28300	COG4481	Protein conserved in bacteria
FORC21_RS28305	COG0668	transmembrane transport
FORC21_RS28315	COG1475	DNA binding
FORC21_RS28320	COG1192	Involved in chromosome partitioning
FORC21_RS28345	COG1847	R3H domain protein
FORC21_RS28360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC21_RS28390	COG0187	DNA topoisomerase II activity
FORC21_RS28395	COG0187	DNA topoisomerase II activity
FORC21_RS28630	COG1774	PSP1 C-terminal conserved region