locus-tag	class	description
FORC5_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC5_RS00015	COG2501	S4 domain
FORC5_RS00025	COG0187	DNA topoisomerase II activity
FORC5_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC5_RS00065	COG0517	IMP dehydrogenase activity
FORC5_RS00065	COG0516	GMP reductase activity
FORC5_RS00070	COG1686	Belongs to the peptidase S11 family
FORC5_RS00100	COG1428	Deoxynucleoside kinase
FORC5_RS00105	COG1428	Deoxynucleoside kinase
FORC5_RS00110	COG1335	isochorismatase
FORC5_RS00120	COG0590	tRNA wobble adenosine to inosine editing
FORC5_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC5_RS00180	COG1982	Orn Lys Arg decarboxylase major
FORC5_RS00190	COG0470	DNA polymerase III
FORC5_RS00195	COG1774	PSP1 C-terminal conserved region
FORC5_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC5_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC5_RS00220	COG2002	toxin-antitoxin pair type II binding
FORC5_RS00230	COG0084	hydrolase, TatD family'
FORC5_RS00250	COG4466	Protein conserved in bacteria
FORC5_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC5_RS00270	COG0251	oxidation-reduction process
FORC5_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC5_RS00305	COG2002	toxin-antitoxin pair type II binding
FORC5_RS00310	COG2244	polysaccharide biosynthetic process
FORC5_RS00315	COG3956	TIGRFAM MazG family protein
FORC5_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC5_RS00340	COG1098	S1 RNA binding domain
FORC5_RS00355	COG2208	phosphoserine phosphatase activity
FORC5_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC5_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC5_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC5_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC5_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC5_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC5_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC5_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC5_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC5_RS00420	COG1396	sequence-specific DNA binding
FORC5_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC5_RS00515	COG3880	PFAM UvrB UvrC protein
FORC5_RS00525	COG0542	response to heat
FORC5_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC5_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
FORC5_RS00560	COG1045	serine acetyltransferase
FORC5_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC5_RS00580	COG3688	RNA-binding protein containing a PIN domain
FORC5_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC5_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
FORC5_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC5_RS00625	COG2813	Specifically methylates the guanine in position
FORC5_RS00640	COG1358	cellular component organization or biogenesis
FORC5_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC5_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC5_RS00770	COG0201	protein transport
FORC5_RS00780	COG0024	Methionine aminopeptidase
FORC5_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC5_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FORC5_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS00855	COG0489	protein tyrosine kinase activity
FORC5_RS00865	COG2194	sulfuric ester hydrolase activity
FORC5_RS00870	COG0726	polysaccharide deacetylase
FORC5_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FORC5_RS00955	COG4856	YbbR-like protein
FORC5_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS01010	COG2011	ABC-type metal ion transport system permease component
FORC5_RS01015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC5_RS01020	COG1464	Belongs to the NlpA lipoprotein family
FORC5_RS01025	COG0604	alcohol dehydrogenase
FORC5_RS01035	COG0277	FAD linked oxidase domain protein
FORC5_RS01040	COG2271	Major facilitator Superfamily
FORC5_RS01050	COG2814	Major facilitator Superfamily
FORC5_RS01065	COG0601	transmembrane transport
FORC5_RS01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC5_RS01075	COG0444	Belongs to the ABC transporter superfamily
FORC5_RS01080	COG4608	Belongs to the ABC transporter superfamily
FORC5_RS01085	COG4166	transmembrane transport
FORC5_RS01095	COG2207	Transcriptional regulator
FORC5_RS01110	COG4166	transmembrane transport
FORC5_RS01115	COG4166	transmembrane transport
FORC5_RS01120	COG0656	L-ascorbic acid biosynthetic process
FORC5_RS01135	COG4149	molybdate abc transporter
FORC5_RS01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC5_RS01145	COG1910	domain protein
FORC5_RS01165	COG0697	spore germination
FORC5_RS01180	COG0204	Acyl-transferase
FORC5_RS01190	COG1609	Transcriptional regulator
FORC5_RS01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS01220	COG5298	Protein conserved in bacteria
FORC5_RS01245	COG0488	(ABC) transporter
FORC5_RS01255	COG0747	negative chemotaxis
FORC5_RS01260	COG0601	transmembrane transport
FORC5_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC5_RS01270	COG0444	Belongs to the ABC transporter superfamily
FORC5_RS01275	COG4608	Belongs to the ABC transporter superfamily
FORC5_RS01280	COG0561	phosphatase activity
FORC5_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FORC5_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC5_RS01325	COG0531	amino acid
FORC5_RS01330	COG2814	Major facilitator Superfamily
FORC5_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC5_RS01350	COG4294	response to UV
FORC5_RS01355	COG0705	Rhomboid family
FORC5_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC5_RS01370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC5_RS01375	COG0864	Transcriptional regulator
FORC5_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
FORC5_RS01385	COG2183	response to ionizing radiation
FORC5_RS01485	COG0802	atpase or kinase
FORC5_RS01490	COG1214	PFAM Peptidase M22, glycoprotease
FORC5_RS01495	COG0456	acetyltransferase
FORC5_RS01505	COG0488	(ABC) transporter
FORC5_RS01520	COG1266	CAAX protease self-immunity
FORC5_RS01540	COG2252	PERMEase
FORC5_RS01550	COG5002	protein histidine kinase activity
FORC5_RS01575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC5_RS01615	COG2205	protein histidine kinase activity
FORC5_RS01620	COG0745	RESPONSE REGULATOR receiver
FORC5_RS01660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC5_RS01670	COG1216	Glycosyl transferase, family 2
FORC5_RS01670	COG0463	Glycosyl transferase, family 2
FORC5_RS01690	COG0697	spore germination
FORC5_RS01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC5_RS01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC5_RS01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC5_RS01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC5_RS01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC5_RS01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC5_RS01775	COG0151	Belongs to the GarS family
FORC5_RS01805	COG0210	DNA helicase
FORC5_RS01815	COG4851	CamS sex pheromone cAM373 precursor
FORC5_RS01830	COG1335	isochorismatase
FORC5_RS01840	COG2011	ABC-type metal ion transport system permease component
FORC5_RS01845	COG1464	Belongs to the NlpA lipoprotein family
FORC5_RS01860	COG0003	Pfam Anion-transporting ATPase
FORC5_RS01865	COG1846	Transcriptional regulator
FORC5_RS01870	COG4682	membrane
FORC5_RS01890	COG1597	lipid kinase activity
FORC5_RS01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC5_RS01910	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS01915	COG2076	Multidrug Resistance protein
FORC5_RS01925	COG2309	aminopeptidase activity
FORC5_RS01940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC5_RS01955	COG4807	Protein conserved in bacteria
FORC5_RS01980	COG1757	Na H antiporter
FORC5_RS01985	COG1473	amidohydrolase
FORC5_RS02000	COG0450	alkyl hydroperoxide reductase
FORC5_RS02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS02030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS02040	COG0492	ferredoxin-NADP+ reductase activity
FORC5_RS02055	COG0166	Belongs to the GPI family
FORC5_RS02080	COG5002	protein histidine kinase activity
FORC5_RS02100	COG3541	Predicted nucleotidyltransferase
FORC5_RS02105	COG2814	Major facilitator Superfamily
FORC5_RS02110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC5_RS02110	COG0723	plastoquinol--plastocyanin reductase activity
FORC5_RS02120	COG0765	amino acid transport
FORC5_RS02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC5_RS02135	COG0840	transmembrane signaling receptor activity
FORC5_RS02160	COG0549	Belongs to the carbamate kinase family
FORC5_RS02165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC5_RS02175	COG0277	FAD linked oxidase domain protein
FORC5_RS02180	COG0366	Alpha amylase catalytic
FORC5_RS02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC5_RS02185	COG2190	(PTS) system
FORC5_RS02185	COG1263	PTS System
FORC5_RS02215	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC5_RS02235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC5_RS02240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC5_RS02245	COG1116	anion transmembrane transporter activity
FORC5_RS02290	COG2270	Major facilitator Superfamily
FORC5_RS02320	COG2310	stress, protein
FORC5_RS02325	COG2310	stress, protein
FORC5_RS02330	COG2310	stress, protein
FORC5_RS02335	COG0861	Integral membrane protein TerC family
FORC5_RS02345	COG3853	Toxic anion resistance protein (TelA)
FORC5_RS02360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC5_RS02370	COG1295	ribonuclease BN
FORC5_RS02375	COG2217	Heavy metal translocating P-type atpase
FORC5_RS02380	COG0697	spore germination
FORC5_RS02400	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS02415	COG3871	stress protein (general stress protein 26)
FORC5_RS02420	COG0387	Pfam Sodium calcium exchanger
FORC5_RS02430	COG0535	radical SAM domain protein
FORC5_RS02450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC5_RS02455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC5_RS02470	COG3829	transcription factor binding
FORC5_RS02480	COG0833	amino acid
FORC5_RS02485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC5_RS02520	COG1263	PTS System
FORC5_RS02520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC5_RS02525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC5_RS02540	COG0463	Glycosyl transferase, family 2
FORC5_RS02550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC5_RS02550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC5_RS02570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC5_RS02590	COG1228	amidohydrolase
FORC5_RS02595	COG1090	epimerase
FORC5_RS02625	COG1988	membrane-bound metal-dependent
FORC5_RS02630	COG1194	a g-specific adenine glycosylase
FORC5_RS02655	COG1132	(ABC) transporter
FORC5_RS02660	COG4129	membrane
FORC5_RS02665	COG0067	glutamate synthase
FORC5_RS02665	COG0069	glutamate synthase activity
FORC5_RS02665	COG0070	glutamate synthase
FORC5_RS02675	COG4555	ABC transporter
FORC5_RS02695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC5_RS02700	COG0735	belongs to the Fur family
FORC5_RS02820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC5_RS02845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC5_RS02860	COG2766	serine protein kinase
FORC5_RS02885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC5_RS02895	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC5_RS02900	COG2268	Band 7 protein
FORC5_RS02910	COG3290	protein histidine kinase activity
FORC5_RS02915	COG4565	transcriptional regulatory protein
FORC5_RS02920	COG2851	Citrate transporter
FORC5_RS02945	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC5_RS02950	COG3842	ATPase activity
FORC5_RS02955	COG1175	transmembrane transport
FORC5_RS02960	COG0395	ABC-type sugar transport system, permease component
FORC5_RS02970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC5_RS02975	COG0745	RESPONSE REGULATOR receiver
FORC5_RS02980	COG5002	protein histidine kinase activity
FORC5_RS02990	COG4990	cell redox homeostasis
FORC5_RS03000	COG3290	protein histidine kinase activity
FORC5_RS03005	COG4565	transcriptional regulatory protein
FORC5_RS03010	COG3493	citrate carrier protein
FORC5_RS03015	COG0281	malic enzyme
FORC5_RS03025	COG0697	spore germination
FORC5_RS03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS03040	COG5002	protein histidine kinase activity
FORC5_RS03055	COG0454	-acetyltransferase
FORC5_RS03055	COG0456	acetyltransferase
FORC5_RS03060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC5_RS03065	COG3383	formate dehydrogenase (NAD+) activity
FORC5_RS03070	COG2427	Protein of unknown function (DUF1641)
FORC5_RS03085	COG0531	amino acid
FORC5_RS03095	COG0640	Transcriptional regulator
FORC5_RS03100	COG2217	Heavy metal translocating P-type atpase
FORC5_RS03105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC5_RS03115	COG3227	Zinc metalloprotease (Elastase)
FORC5_RS03135	COG2720	vancomycin resistance protein
FORC5_RS03140	COG1316	TRANSCRIPTIONal
FORC5_RS03145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS03150	COG0346	lactoylglutathione lyase activity
FORC5_RS03155	COG1253	flavin adenine dinucleotide binding
FORC5_RS03160	COG1027	Aspartate ammonia-lyase
FORC5_RS03165	COG1620	l-lactate permease
FORC5_RS03180	COG3104	oligopeptide transport
FORC5_RS03185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS03190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS03195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS03205	COG2226	methyltransferase
FORC5_RS03215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC5_RS03225	COG4548	von Willebrand factor, type A
FORC5_RS03230	COG0714	Associated with various cellular activities
FORC5_RS03250	COG0531	amino acid
FORC5_RS03255	COG2188	Transcriptional regulator
FORC5_RS03260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC5_RS03260	COG1263	PTS System
FORC5_RS03265	COG0366	Alpha amylase catalytic
FORC5_RS03280	COG0697	spore germination
FORC5_RS03285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC5_RS03290	COG1115	amino acid carrier protein
FORC5_RS03300	COG1126	abc transporter atp-binding protein
FORC5_RS03305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC5_RS03310	COG0765	amino acid transport
FORC5_RS03315	COG0765	amino acid transport
FORC5_RS03320	COG0833	amino acid
FORC5_RS03335	COG2378	regulation of single-species biofilm formation
FORC5_RS03340	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC5_RS03345	COG5002	protein histidine kinase activity
FORC5_RS03370	COG0659	secondary active sulfate transmembrane transporter activity
FORC5_RS03385	COG2271	Major facilitator Superfamily
FORC5_RS03390	COG1846	Transcriptional regulator
FORC5_RS03395	COG0477	Major facilitator Superfamily
FORC5_RS03400	COG1609	Transcriptional regulator
FORC5_RS03405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC5_RS03420	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC5_RS03425	COG1879	ABC-type sugar transport system periplasmic component
FORC5_RS03445	COG1063	alcohol dehydrogenase
FORC5_RS03495	COG0840	transmembrane signaling receptor activity
FORC5_RS03500	COG1388	LysM domain
FORC5_RS03500	COG3584	3D domain protein
FORC5_RS03505	COG1476	TRANSCRIPTIONal
FORC5_RS03525	COG3104	oligopeptide transport
FORC5_RS03530	COG1114	Component of the transport system for branched-chain amino acids
FORC5_RS03545	COG1113	amino acid transport
FORC5_RS03550	COG2252	PERMEase
FORC5_RS03575	COG2153	protein acetylation
FORC5_RS03585	COG0569	domain protein
FORC5_RS03585	COG0475	glutathione-regulated potassium exporter activity
FORC5_RS03595	COG1845	cytochrome c oxidase, subunit III
FORC5_RS03600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC5_RS03610	COG0833	amino acid
FORC5_RS03615	COG4990	cell redox homeostasis
FORC5_RS03630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC5_RS03635	COG0697	spore germination
FORC5_RS03640	COG0531	amino acid
FORC5_RS03655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC5_RS03660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC5_RS03665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC5_RS03665	COG1918	ferrous iron import across plasma membrane
FORC5_RS03670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC5_RS03675	COG0573	inorganic phosphate transmembrane transporter activity
FORC5_RS03680	COG0581	inorganic phosphate transmembrane transporter activity
FORC5_RS03685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC5_RS03805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FORC5_RS03830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC5_RS03835	COG1116	anion transmembrane transporter activity
FORC5_RS03840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC5_RS03845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC5_RS03850	COG0352	thiamine-phosphate diphosphorylase activity
FORC5_RS03855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC5_RS03860	COG2104	thiamine diphosphate biosynthetic process
FORC5_RS03870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC5_RS03875	COG0351	phosphomethylpyrimidine kinase
FORC5_RS03915	COG2205	protein histidine kinase activity
FORC5_RS03920	COG2814	Major facilitator Superfamily
FORC5_RS03925	COG1846	Transcriptional regulator
FORC5_RS03935	COG2252	PERMEase
FORC5_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS03955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC5_RS03960	COG1621	beta-fructofuranosidase activity
FORC5_RS03965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC5_RS03965	COG1263	PTS System
FORC5_RS03970	COG1609	Transcriptional regulator
FORC5_RS04020	COG0778	Nitroreductase
FORC5_RS04025	COG2719	SpoVR family
FORC5_RS04035	COG3591	Belongs to the peptidase S1B family
FORC5_RS04060	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC5_RS04065	COG1937	Protein conserved in bacteria
FORC5_RS04070	COG0425	Belongs to the sulfur carrier protein TusA family
FORC5_RS04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS04075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS04075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS04080	COG0425	Belongs to the sulfur carrier protein TusA family
FORC5_RS04085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS04085	COG0425	Belongs to the sulfur carrier protein TusA family
FORC5_RS04090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS04095	COG2210	Belongs to the sulfur carrier protein TusA family
FORC5_RS04100	COG0730	response to heat
FORC5_RS04110	COG1316	TRANSCRIPTIONal
FORC5_RS04115	COG0604	alcohol dehydrogenase
FORC5_RS04120	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC5_RS04135	COG3711	transcriptional antiterminator
FORC5_RS04135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC5_RS04140	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC5_RS04145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC5_RS04170	COG3584	3D domain protein
FORC5_RS04170	COG1388	LysM domain
FORC5_RS04175	COG0577	efflux transmembrane transporter activity
FORC5_RS04180	COG1136	(ABC) transporter
FORC5_RS04190	COG5522	Integral membrane protein (intg_mem_TP0381)
FORC5_RS04205	COG1114	Component of the transport system for branched-chain amino acids
FORC5_RS04210	COG3546	catalase activity
FORC5_RS04245	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS04280	COG0531	amino acid
FORC5_RS04285	COG0475	glutathione-regulated potassium exporter activity
FORC5_RS04295	COG1737	Transcriptional regulator
FORC5_RS04305	COG1263	PTS System
FORC5_RS04305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC5_RS04315	COG2259	Doxx family
FORC5_RS04335	COG1522	sequence-specific DNA binding
FORC5_RS04340	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC5_RS04340	COG0165	Argininosuccinate lyase
FORC5_RS04345	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS04365	COG1309	transcriptional regulator
FORC5_RS04370	COG2814	Major facilitator Superfamily
FORC5_RS04375	COG1733	regulation of RNA biosynthetic process
FORC5_RS04390	COG4533	DNA binding
FORC5_RS04395	COG2211	Major facilitator Superfamily
FORC5_RS04405	COG0693	protein deglycase activity
FORC5_RS04410	COG0753	catalase activity
FORC5_RS04410	COG0693	protein deglycase activity
FORC5_RS04420	COG0531	amino acid
FORC5_RS04425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC5_RS04435	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS04445	COG1132	(ABC) transporter
FORC5_RS04450	COG1132	(ABC) transporter
FORC5_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC5_RS04460	COG0765	amino acid transport
FORC5_RS04465	COG1126	abc transporter atp-binding protein
FORC5_RS04480	COG0189	ligase activity
FORC5_RS04515	COG0028	Belongs to the TPP enzyme family
FORC5_RS04520	COG3527	Alpha-acetolactate decarboxylase
FORC5_RS04530	COG0561	phosphatase activity
FORC5_RS04545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC5_RS04565	COG0659	secondary active sulfate transmembrane transporter activity
FORC5_RS04570	COG2244	polysaccharide biosynthetic process
FORC5_RS04590	COG1024	Enoyl-CoA hydratase
FORC5_RS04610	COG1363	Peptidase, m42
FORC5_RS04645	COG0601	transmembrane transport
FORC5_RS04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC5_RS04655	COG0444	Belongs to the ABC transporter superfamily
FORC5_RS04660	COG4608	Belongs to the ABC transporter superfamily
FORC5_RS04670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS04685	COG0577	efflux transmembrane transporter activity
FORC5_RS04685	COG1136	(ABC) transporter
FORC5_RS04735	COG0477	Major facilitator Superfamily
FORC5_RS04740	COG3290	protein histidine kinase activity
FORC5_RS04745	COG4565	transcriptional regulatory protein
FORC5_RS04750	COG3181	Tripartite tricarboxylate transporter family receptor
FORC5_RS04785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FORC5_RS04805	COG0789	Transcriptional regulator
FORC5_RS04805	COG4978	Transcriptional regulator
FORC5_RS04820	COG0305	Participates in initiation and elongation during chromosome replication
FORC5_RS04850	COG0477	Major facilitator Superfamily
FORC5_RS04860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS04870	COG1073	alpha beta
FORC5_RS04915	COG1183	phosphatidylcholine synthase activity
FORC5_RS04930	COG2376	Dihydroxyacetone kinase
FORC5_RS04980	COG1388	LysM domain
FORC5_RS04980	COG3584	3D domain protein
FORC5_RS04985	COG0791	NLP P60 protein
FORC5_RS04985	COG1388	LysM domain
FORC5_RS04990	COG2373	Large extracellular alpha-helical protein
FORC5_RS05010	COG0596	Alpha beta hydrolase
FORC5_RS05060	COG1191	sigma factor activity
FORC5_RS05070	COG2208	phosphoserine phosphatase activity
FORC5_RS05075	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC5_RS05080	COG5002	protein histidine kinase activity
FORC5_RS05080	COG2205	protein histidine kinase activity
FORC5_RS05080	COG0784	Response regulator, receiver
FORC5_RS05120	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FORC5_RS05140	COG0420	3'-5' exonuclease activity
FORC5_RS05145	COG4717	serine-type aminopeptidase activity
FORC5_RS05155	COG0346	lactoylglutathione lyase activity
FORC5_RS05160	COG0346	lactoylglutathione lyase activity
FORC5_RS05165	COG0457	Tetratricopeptide repeat
FORC5_RS05175	COG2267	carboxylic ester hydrolase activity
FORC5_RS05195	COG2140	Oxalate decarboxylase
FORC5_RS05205	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC5_RS05210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC5_RS05220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC5_RS05225	COG1695	Transcriptional regulator
FORC5_RS05255	COG3973	AAA domain
FORC5_RS05290	COG4980	gas vesicle protein
FORC5_RS05295	COG0537	adenosine 5'-monophosphoramidase activity
FORC5_RS05300	COG1131	(ABC) transporter
FORC5_RS05305	COG4473	ABC transporter
FORC5_RS05325	COG3402	PFAM membrane-flanked domain
FORC5_RS05330	COG3428	Bacterial PH domain
FORC5_RS05365	COG0697	spore germination
FORC5_RS05370	COG3402	PFAM membrane-flanked domain
FORC5_RS05375	COG3428	Bacterial PH domain
FORC5_RS05380	COG2329	Antibiotic biosynthesis monooxygenase
FORC5_RS05385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC5_RS05400	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FORC5_RS05435	COG1309	transcriptional regulator
FORC5_RS05440	COG1511	domain protein
FORC5_RS05470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS05475	COG1609	Transcriptional regulator
FORC5_RS05485	COG1234	tRNA 3'-trailer cleavage
FORC5_RS05490	COG0095	Lipoate-protein ligase
FORC5_RS05500	COG0318	PFAM AMP-dependent synthetase and ligase
FORC5_RS05510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC5_RS05520	COG4208	sulfate ABC transporter
FORC5_RS05655	COG1073	alpha beta
FORC5_RS05660	COG1408	metallophosphoesterase
FORC5_RS05665	COG1078	dGTPase activity
FORC5_RS05675	COG1595	DNA-templated transcription, initiation
FORC5_RS05680	COG2207	Transcriptional regulator
FORC5_RS05680	COG3708	Transcriptional regulator
FORC5_RS05690	COG2205	protein histidine kinase activity
FORC5_RS05695	COG0745	RESPONSE REGULATOR receiver
FORC5_RS05715	COG0501	Belongs to the peptidase M48B family
FORC5_RS05720	COG0840	transmembrane signaling receptor activity
FORC5_RS05725	COG3693	PFAM glycoside hydrolase, family 10
FORC5_RS05735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC5_RS05740	COG2224	Isocitrate lyase
FORC5_RS05755	COG1278	Cold shock
FORC5_RS05775	COG0398	Pfam SNARE associated Golgi protein
FORC5_RS05835	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC5_RS05860	COG0367	asparagine synthase
FORC5_RS05870	COG0753	catalase activity
FORC5_RS05875	COG0004	ammonium transporteR
FORC5_RS05895	COG2996	Protein conserved in bacteria
FORC5_RS05910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS05925	COG0561	phosphatase activity
FORC5_RS05950	COG2267	carboxylic ester hydrolase activity
FORC5_RS05970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC5_RS05975	COG5504	Zn-dependent protease
FORC5_RS05985	COG0180	Tryptophanyl-tRNA synthetase
FORC5_RS05995	COG4166	transmembrane transport
FORC5_RS06000	COG0601	transmembrane transport
FORC5_RS06005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC5_RS06010	COG0444	Belongs to the ABC transporter superfamily
FORC5_RS06015	COG4608	Belongs to the ABC transporter superfamily
FORC5_RS06020	COG0534	Mate efflux family protein
FORC5_RS06025	COG4166	transmembrane transport
FORC5_RS06045	COG0861	Integral membrane protein TerC family
FORC5_RS06065	COG1164	Oligoendopeptidase f
FORC5_RS06080	COG2346	COG2346, Truncated hemoglobins
FORC5_RS06085	COG4116	CYTH
FORC5_RS06095	COG2357	RelA SpoT domain protein
FORC5_RS06105	COG0564	pseudouridine synthase activity
FORC5_RS06120	COG0772	Belongs to the SEDS family
FORC5_RS06125	COG1216	Glycosyl transferase, family 2
FORC5_RS06145	COG0457	Tetratricopeptide repeat
FORC5_RS06145	COG0463	Glycosyl transferase, family 2
FORC5_RS06165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC5_RS06180	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC5_RS06225	COG2153	protein acetylation
FORC5_RS06235	COG2382	esterase
FORC5_RS06250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC5_RS06265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC5_RS06265	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC5_RS06300	COG1620	l-lactate permease
FORC5_RS06305	COG5634	Uncharacterized conserved protein (DUF2278)
FORC5_RS06355	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC5_RS06365	COG1476	TRANSCRIPTIONal
FORC5_RS06510	COG0758	DNA mediated transformation
FORC5_RS06520	COG4974	Belongs to the 'phage' integrase family
FORC5_RS06545	COG1686	Belongs to the peptidase S11 family
FORC5_RS06550	COG0681	Belongs to the peptidase S26 family
FORC5_RS06585	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS06595	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC5_RS06600	COG1177	transmembrane transport
FORC5_RS06615	COG2409	Drug exporters of the RND superfamily
FORC5_RS06625	COG0564	pseudouridine synthase activity
FORC5_RS06635	COG2340	Cysteine-rich secretory protein family
FORC5_RS06640	COG0247	lactate metabolic process
FORC5_RS06645	COG0277	FAD linked oxidase domain protein
FORC5_RS06650	COG3835	regulator
FORC5_RS06660	COG0745	RESPONSE REGULATOR receiver
FORC5_RS06665	COG5002	protein histidine kinase activity
FORC5_RS06670	COG2186	Transcriptional regulator
FORC5_RS06690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC5_RS06700	COG2116	formate transmembrane transporter activity
FORC5_RS06705	COG0861	Integral membrane protein TerC family
FORC5_RS06710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC5_RS06720	COG2030	dehydratase
FORC5_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS06745	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC5_RS06755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC5_RS06770	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC5_RS06775	COG3842	ATPase activity
FORC5_RS06800	COG1349	DNA-binding transcription factor activity
FORC5_RS06815	COG0235	Class ii aldolase
FORC5_RS06825	COG2861	carbohydrate metabolic process
FORC5_RS06835	COG3852	Histidine kinase
FORC5_RS06840	COG1846	Transcriptional regulator
FORC5_RS06850	COG2318	DinB family
FORC5_RS06860	COG5002	protein histidine kinase activity
FORC5_RS06870	COG0720	synthase
FORC5_RS06885	COG4873	Protein conserved in bacteria
FORC5_RS06925	COG1780	Probably involved in ribonucleotide reductase function
FORC5_RS06930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC5_RS06935	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC5_RS06940	COG1725	Transcriptional regulator
FORC5_RS06945	COG1131	(ABC) transporter
FORC5_RS06955	COG1131	(ABC) transporter
FORC5_RS06960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC5_RS06965	COG1266	CAAX protease self-immunity
FORC5_RS06975	COG1522	sequence-specific DNA binding
FORC5_RS06985	COG1335	isochorismatase
FORC5_RS06995	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC5_RS07000	COG2070	2-Nitropropane dioxygenase
FORC5_RS07005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC5_RS07015	COG1696	Membrane protein involved in D-alanine export
FORC5_RS07040	COG0716	FMN binding
FORC5_RS07095	COG1846	Transcriptional regulator
FORC5_RS07105	COG1301	dicarboxylic acid transport
FORC5_RS07110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC5_RS07115	COG4709	membrane
FORC5_RS07120	COG3874	Sporulation protein YtfJ
FORC5_RS07150	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC5_RS07155	COG0028	Belongs to the TPP enzyme family
FORC5_RS07160	COG0440	acetolactate synthase activity
FORC5_RS07235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC5_RS07250	COG1183	phosphatidylcholine synthase activity
FORC5_RS07255	COG1368	sulfuric ester hydrolase activity
FORC5_RS07265	COG0019	diaminopimelate decarboxylase activity
FORC5_RS07285	COG0529	Catalyzes the synthesis of activated sulfate
FORC5_RS07290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC5_RS07310	COG1648	precorrin-2 dehydrogenase activity
FORC5_RS07320	COG0733	neurotransmitter:sodium symporter activity
FORC5_RS07340	COG1757	Na H antiporter
FORC5_RS07355	COG4758	membrane
FORC5_RS07360	COG4585	Histidine kinase
FORC5_RS07365	COG2197	response regulator
FORC5_RS07375	COG1114	Component of the transport system for branched-chain amino acids
FORC5_RS07430	COG0730	response to heat
FORC5_RS07435	COG0306	phosphate transporter
FORC5_RS07440	COG1392	Phosphate transport regulator
FORC5_RS07445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC5_RS07460	COG3852	Histidine kinase
FORC5_RS07465	COG1801	Protein of unknown function DUF72
FORC5_RS07475	COG0582	viral genome integration into host DNA
FORC5_RS07480	COG5002	protein histidine kinase activity
FORC5_RS07495	COG0392	lysyltransferase activity
FORC5_RS07495	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FORC5_RS07510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC5_RS07515	COG1686	Belongs to the peptidase S11 family
FORC5_RS07520	COG2715	membrane protein required for spore maturation
FORC5_RS07525	COG0700	Nucleoside recognition
FORC5_RS07530	COG1187	pseudouridine synthase activity
FORC5_RS07540	COG1333	cytochrome c biogenesis protein
FORC5_RS07545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC5_RS07550	COG0745	RESPONSE REGULATOR receiver
FORC5_RS07555	COG5002	protein histidine kinase activity
FORC5_RS07560	COG2096	Adenosyltransferase
FORC5_RS07575	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FORC5_RS07580	COG1141	Ferredoxin
FORC5_RS07590	COG0514	ATP-dependent DNA helicase (RecQ)
FORC5_RS07595	COG1266	CAAX protease self-immunity
FORC5_RS07605	COG1408	metallophosphoesterase
FORC5_RS07610	COG0789	Transcriptional regulator
FORC5_RS07620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC5_RS07640	COG0492	ferredoxin-NADP+ reductase activity
FORC5_RS07645	COG0252	asparaginase activity
FORC5_RS07715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC5_RS07730	COG0142	geranyltranstransferase activity
FORC5_RS07740	COG0142	geranyltranstransferase activity
FORC5_RS07765	COG0457	Tetratricopeptide repeat
FORC5_RS07785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC5_RS07790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC5_RS07790	COG2010	Cytochrome c
FORC5_RS07795	COG4347	Protein of unknown function (DUF1405)
FORC5_RS07810	COG2738	Putative neutral zinc metallopeptidase
FORC5_RS07820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS07825	COG1694	Mazg nucleotide pyrophosphohydrolase
FORC5_RS07845	COG0438	transferase activity, transferring glycosyl groups
FORC5_RS07885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC5_RS07885	COG1199	ATP-dependent helicase activity
FORC5_RS07905	COG3935	DnaD domain protein
FORC5_RS07910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC5_RS07920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC5_RS07920	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC5_RS07970	COG0116	Belongs to the methyltransferase superfamily
FORC5_RS07985	COG0457	Tetratricopeptide repeat
FORC5_RS08005	COG1199	ATP-dependent helicase activity
FORC5_RS08010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC5_RS08020	COG0024	Methionine aminopeptidase
FORC5_RS08030	COG2233	PERMEase
FORC5_RS08035	COG2311	Membrane
FORC5_RS08040	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC5_RS08050	COG0456	acetyltransferase
FORC5_RS08075	COG0754	glutathionylspermidine amidase activity
FORC5_RS08090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC5_RS08105	COG3944	biosynthesis protein
FORC5_RS08115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC5_RS08130	COG1215	transferase activity, transferring glycosyl groups
FORC5_RS08135	COG0438	transferase activity, transferring glycosyl groups
FORC5_RS08150	COG0454	-acetyltransferase
FORC5_RS08170	COG0328	RNA-DNA hybrid ribonuclease activity
FORC5_RS08205	COG3403	YqcI/YcgG family
FORC5_RS08210	COG1280	lysine exporter protein (LysE YggA)
FORC5_RS08230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC5_RS08235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC5_RS08245	COG0475	glutathione-regulated potassium exporter activity
FORC5_RS08250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC5_RS08255	COG4978	Transcriptional regulator
FORC5_RS08255	COG0789	Transcriptional regulator
FORC5_RS08265	COG2323	membrane
FORC5_RS08270	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC5_RS08310	COG1923	regulation of RNA biosynthetic process
FORC5_RS08320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC5_RS08325	COG1360	Flagellar Motor Protein
FORC5_RS08330	COG2201	protein-glutamate methylesterase activity
FORC5_RS08335	COG2198	Histidine kinase
FORC5_RS08335	COG0643	Histidine kinase
FORC5_RS08340	COG1776	CheC inhibitor of MCP methylation
FORC5_RS08340	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC5_RS08355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC5_RS08375	COG1256	bacterial-type flagellum assembly
FORC5_RS08380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC5_RS08385	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC5_RS08400	COG1815	bacterial-type flagellum-dependent cell motility
FORC5_RS08405	COG1558	bacterial-type flagellum-dependent cell motility
FORC5_RS08415	COG1766	The M ring may be actively involved in energy transduction
FORC5_RS08420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC5_RS08430	COG1157	protein secretion by the type III secretion system
FORC5_RS08450	COG1749	Flagellar hook protein flgE
FORC5_RS08465	COG0835	chemotaxis
FORC5_RS08465	COG0784	Response regulator, receiver
FORC5_RS08475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC5_RS08480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC5_RS08485	COG0741	lytic transglycosylase activity
FORC5_RS08495	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC5_RS08500	COG1776	CheC inhibitor of MCP methylation
FORC5_RS08500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC5_RS08510	COG1338	Plays a role in the flagellum-specific transport system
FORC5_RS08515	COG1987	bacterial-type flagellum assembly
FORC5_RS08525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC5_RS08530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC5_RS08535	COG1419	protein localization to endoplasmic reticulum
FORC5_RS08540	COG4786	Flagellar basal body rod
FORC5_RS08545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC5_RS08580	COG2329	Antibiotic biosynthesis monooxygenase
FORC5_RS08605	COG0583	DNA-binding transcription factor activity
FORC5_RS08650	COG0406	alpha-ribazole phosphatase activity
FORC5_RS08680	COG0367	asparagine synthase
FORC5_RS08710	COG1802	Transcriptional regulator
FORC5_RS08715	COG0697	spore germination
FORC5_RS08725	COG0523	cobalamin synthesis protein
FORC5_RS08730	COG0701	Predicted permease
FORC5_RS08745	COG1757	Na H antiporter
FORC5_RS08750	COG0789	Transcriptional regulator
FORC5_RS08780	COG0534	Mate efflux family protein
FORC5_RS08785	COG3340	Belongs to the peptidase S51 family
FORC5_RS08805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC5_RS09050	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC5_RS09050	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC5_RS09075	COG1484	DNA-dependent DNA replication
FORC5_RS09115	COG2733	membrane
FORC5_RS09150	COG1131	(ABC) transporter
FORC5_RS09170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC5_RS09175	COG0528	UMP kinase activity
FORC5_RS09185	COG1027	Aspartate ammonia-lyase
FORC5_RS09190	COG0281	malic enzyme
FORC5_RS09195	COG4191	Histidine kinase
FORC5_RS09200	COG0784	Response regulator, receiver
FORC5_RS09205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC5_RS09225	COG3620	sequence-specific DNA binding
FORC5_RS09265	COG2814	Major facilitator Superfamily
FORC5_RS09290	COG0477	Major facilitator Superfamily
FORC5_RS09305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC5_RS09310	COG2223	nitrite transmembrane transporter activity
FORC5_RS09315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC5_RS09335	COG0733	neurotransmitter:sodium symporter activity
FORC5_RS09345	COG5566	PFAM Mor transcription activator
FORC5_RS09350	COG2323	membrane
FORC5_RS09370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC5_RS09380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC5_RS09385	COG0028	Belongs to the TPP enzyme family
FORC5_RS09405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC5_RS09430	COG2814	Major facilitator Superfamily
FORC5_RS09435	COG3384	dioxygenase
FORC5_RS09445	COG3279	Response regulator of the LytR AlgR family
FORC5_RS09450	COG0427	acetyl-CoA hydrolase
FORC5_RS09470	COG4166	transmembrane transport
FORC5_RS09475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS09495	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC5_RS09510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC5_RS09520	COG0531	amino acid
FORC5_RS09550	COG2309	aminopeptidase activity
FORC5_RS09565	COG0456	acetyltransferase
FORC5_RS09575	COG1266	CAAX protease self-immunity
FORC5_RS09580	COG1309	transcriptional regulator
FORC5_RS09585	COG2390	Transcriptional regulator
FORC5_RS09595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS09600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC5_RS09640	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC5_RS09660	COG0583	DNA-binding transcription factor activity
FORC5_RS09675	COG0006	proline dipeptidase activity
FORC5_RS09685	COG2132	Multicopper oxidase
FORC5_RS09695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC5_RS09715	COG1114	Component of the transport system for branched-chain amino acids
FORC5_RS09725	COG2372	response to copper ion
FORC5_RS09725	COG1276	copper resistance
FORC5_RS09730	COG4549	nuclear export factor GLE1
FORC5_RS09735	COG0697	spore germination
FORC5_RS09740	COG0583	DNA-binding transcription factor activity
FORC5_RS09745	COG1959	2 iron, 2 sulfur cluster binding
FORC5_RS09750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC5_RS09755	COG0778	Nitroreductase
FORC5_RS09770	COG0628	permease
FORC5_RS09780	COG1231	oxidoreductase activity
FORC5_RS09785	COG0523	cobalamin synthesis protein
FORC5_RS09795	COG0411	ABC transporter
FORC5_RS09815	COG0583	DNA-binding transcription factor activity
FORC5_RS09845	COG1271	oxidase subunit
FORC5_RS09850	COG1294	oxidase, subunit
FORC5_RS09855	COG4988	ABC transporter
FORC5_RS09860	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC5_RS09870	COG1216	Glycosyl transferase, family 2
FORC5_RS09910	COG1686	Belongs to the peptidase S11 family
FORC5_RS09925	COG0791	NLP P60 protein
FORC5_RS09925	COG1388	LysM domain
FORC5_RS09935	COG1132	(ABC) transporter
FORC5_RS09940	COG0745	RESPONSE REGULATOR receiver
FORC5_RS09945	COG5002	protein histidine kinase activity
FORC5_RS09950	COG0300	oxidoreductase activity
FORC5_RS09980	COG0460	homoserine dehydrogenase
FORC5_RS10005	COG1316	TRANSCRIPTIONal
FORC5_RS10015	COG0745	RESPONSE REGULATOR receiver
FORC5_RS10020	COG5002	protein histidine kinase activity
FORC5_RS10035	COG1285	pathogenesis
FORC5_RS10040	COG1247	-acetyltransferase
FORC5_RS10060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC5_RS10070	COG1082	Xylose isomerase domain protein TIM barrel
FORC5_RS10080	COG2814	Major facilitator Superfamily
FORC5_RS10085	COG1279	arginine transmembrane transporter activity
FORC5_RS10090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS10100	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC5_RS10135	COG0577	efflux transmembrane transporter activity
FORC5_RS10140	COG2002	toxin-antitoxin pair type II binding
FORC5_RS10145	COG1404	Belongs to the peptidase S8 family
FORC5_RS10150	COG0640	Transcriptional regulator
FORC5_RS10155	COG0667	Aldo Keto reductase
FORC5_RS10160	COG2814	Major facilitator Superfamily
FORC5_RS10170	COG3152	Membrane
FORC5_RS10195	COG0840	transmembrane signaling receptor activity
FORC5_RS10215	COG3949	Membrane
FORC5_RS10220	COG0783	Belongs to the Dps family
FORC5_RS10235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC5_RS10245	COG1231	oxidoreductase activity
FORC5_RS10250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS10255	COG4989	oxidoreductase activity
FORC5_RS10260	COG0523	cobalamin synthesis protein
FORC5_RS10265	COG0456	acetyltransferase
FORC5_RS10270	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC5_RS10280	COG0702	epimerase
FORC5_RS10290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC5_RS10300	COG4166	transmembrane transport
FORC5_RS10325	COG5337	Spore coat protein CotH
FORC5_RS10330	COG1051	belongs to the nudix hydrolase family
FORC5_RS10335	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS10340	COG2244	polysaccharide biosynthetic process
FORC5_RS10350	COG0701	Predicted permease
FORC5_RS10355	COG3689	TIGRFAM TIGR03943 family protein
FORC5_RS10360	COG1607	acyl-coa hydrolase
FORC5_RS10365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC5_RS10380	COG0702	epimerase
FORC5_RS10385	COG2839	Protein conserved in bacteria
FORC5_RS10390	COG1253	flavin adenine dinucleotide binding
FORC5_RS10405	COG1114	Component of the transport system for branched-chain amino acids
FORC5_RS10410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC5_RS10430	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS10440	COG1876	peptidase activity
FORC5_RS10450	COG0154	amidase activity
FORC5_RS10455	COG2211	Major facilitator Superfamily
FORC5_RS10480	COG0561	phosphatase activity
FORC5_RS10495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC5_RS10510	COG1819	glycosyl
FORC5_RS10515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS10520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS10550	COG0456	acetyltransferase
FORC5_RS10585	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC5_RS10675	COG3874	Sporulation protein YtfJ
FORC5_RS10700	COG2226	methyltransferase
FORC5_RS10725	COG0346	lactoylglutathione lyase activity
FORC5_RS10735	COG0604	alcohol dehydrogenase
FORC5_RS10740	COG1595	DNA-templated transcription, initiation
FORC5_RS10765	COG0386	Belongs to the glutathione peroxidase family
FORC5_RS10770	COG1305	Transglutaminase-like
FORC5_RS10775	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FORC5_RS10780	COG0714	Associated with various cellular activities
FORC5_RS10785	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FORC5_RS10790	COG1140	nitrate reductase beta subunit
FORC5_RS10795	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FORC5_RS10800	COG2181	nitrate reductase activity
FORC5_RS10805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC5_RS10810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC5_RS10815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC5_RS10820	COG0303	'Molybdopterin
FORC5_RS10825	COG0314	molybdopterin synthase activity
FORC5_RS10835	COG2223	nitrite transmembrane transporter activity
FORC5_RS10850	COG1648	precorrin-2 dehydrogenase activity
FORC5_RS10860	COG1587	Uroporphyrinogen-III synthase
FORC5_RS10860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC5_RS10865	COG2146	nitrite reductase [NAD(P)H] activity
FORC5_RS10870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC5_RS10875	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FORC5_RS10910	COG2359	stage V sporulation protein S
FORC5_RS10930	COG2801	Transposase and inactivated derivatives
FORC5_RS10945	COG0457	Tetratricopeptide repeat
FORC5_RS10960	COG1418	mRNA catabolic process
FORC5_RS10965	COG0488	(ABC) transporter
FORC5_RS10980	COG0629	single-stranded DNA binding
FORC5_RS10985	COG1413	lyase activity
FORC5_RS11000	COG2136	Putative SAM-dependent methyltransferase
FORC5_RS11000	COG2521	methyltransferase
FORC5_RS11005	COG0018	arginyl-trna synthetase
FORC5_RS11055	COG0017	Asparaginyl-tRNA synthetase
FORC5_RS11060	COG0733	neurotransmitter:sodium symporter activity
FORC5_RS11085	COG2610	gluconate transmembrane transporter activity
FORC5_RS11095	COG1794	racemase activity, acting on amino acids and derivatives
FORC5_RS11105	COG0456	acetyltransferase
FORC5_RS11115	COG3655	Transcriptional regulator
FORC5_RS11120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC5_RS11130	COG1131	(ABC) transporter
FORC5_RS11135	COG4473	ABC transporter
FORC5_RS11145	COG0546	phosphoglycolate phosphatase activity
FORC5_RS11160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC5_RS11175	COG0768	penicillin binding
FORC5_RS11185	COG0204	Acyl-transferase
FORC5_RS11190	COG1272	protein, Hemolysin III
FORC5_RS11200	COG0805	protein transport
FORC5_RS11210	COG1307	EDD domain protein, DegV family
FORC5_RS11220	COG1999	signal sequence binding
FORC5_RS11225	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC5_RS11230	COG0367	asparagine synthase
FORC5_RS11245	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS11250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS11255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC5_RS11275	COG1335	isochorismatase
FORC5_RS11285	COG0668	transmembrane transport
FORC5_RS11290	COG2203	Gaf domain
FORC5_RS11290	COG4585	Histidine kinase
FORC5_RS11295	COG2197	response regulator
FORC5_RS11300	COG1737	Transcriptional regulator
FORC5_RS11305	COG0384	phenazine biosynthesis protein PhzF
FORC5_RS11310	COG1064	alcohol dehydrogenase
FORC5_RS11315	COG2801	Transposase and inactivated derivatives
FORC5_RS11345	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC5_RS11380	COG0517	IMP dehydrogenase activity
FORC5_RS11380	COG1125	glycine betaine transport
FORC5_RS11385	COG1174	glycine betaine transport
FORC5_RS11420	COG1253	flavin adenine dinucleotide binding
FORC5_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS11430	COG5506	Protein of unknown function (DUF1694)
FORC5_RS11445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC5_RS11450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORC5_RS11455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FORC5_RS11460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC5_RS11465	COG0456	acetyltransferase
FORC5_RS11470	COG3829	transcription factor binding
FORC5_RS11475	COG1509	lysine 2,3-aminomutase activity
FORC5_RS11510	COG0515	serine threonine protein kinase
FORC5_RS11510	COG3064	Membrane
FORC5_RS11510	COG4991	sh3 domain protein
FORC5_RS11520	COG0671	phosphoesterase, PA-phosphatase related
FORC5_RS11525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC5_RS11530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC5_RS11600	COG0300	oxidoreductase activity
FORC5_RS11620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC5_RS11620	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC5_RS11630	COG2814	Major facilitator Superfamily
FORC5_RS11635	COG4841	protein insertion into membrane
FORC5_RS11640	COG0372	Belongs to the citrate synthase family
FORC5_RS11645	COG2079	MmgE PrpD family protein
FORC5_RS11650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC5_RS11655	COG1960	acyl-CoA dehydrogenase activity
FORC5_RS11660	COG2084	Dehydrogenase
FORC5_RS11670	COG1280	lysine exporter protein (LysE YggA)
FORC5_RS11675	COG1024	Enoyl-CoA hydratase
FORC5_RS11690	COG0420	3'-5' exonuclease activity
FORC5_RS11695	COG0419	ATPase involved in DNA repair
FORC5_RS11725	COG2223	nitrite transmembrane transporter activity
FORC5_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS11735	COG1169	isochorismate synthase
FORC5_RS11740	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC5_RS11745	COG3433	isochorismatase activity
FORC5_RS11745	COG1535	isochorismatase
FORC5_RS11750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC5_RS11755	COG3251	PFAM MbtH domain protein
FORC5_RS11760	COG2814	Major facilitator Superfamily
FORC5_RS11775	COG0776	regulation of translation
FORC5_RS11785	COG2318	DinB family
FORC5_RS11795	COG1115	amino acid carrier protein
FORC5_RS11820	COG1187	pseudouridine synthase activity
FORC5_RS11825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC5_RS11830	COG1136	(ABC) transporter
FORC5_RS11860	COG0028	Belongs to the TPP enzyme family
FORC5_RS11900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC5_RS11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS11950	COG1247	-acetyltransferase
FORC5_RS11975	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FORC5_RS11985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS12015	COG0583	DNA-binding transcription factor activity
FORC5_RS12020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC5_RS12040	COG0583	DNA-binding transcription factor activity
FORC5_RS12045	COG2258	MOSC domain
FORC5_RS12060	COG1132	(ABC) transporter
FORC5_RS12065	COG1132	(ABC) transporter
FORC5_RS12100	COG1396	sequence-specific DNA binding
FORC5_RS12130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC5_RS12135	COG1595	DNA-templated transcription, initiation
FORC5_RS12160	COG1649	PFAM Uncharacterised BCR, COG1649
FORC5_RS12185	COG2971	BadF BadG BcrA BcrD
FORC5_RS12205	COG1846	Transcriptional regulator
FORC5_RS12220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS12245	COG1309	transcriptional regulator
FORC5_RS12265	COG0500	methyltransferase
FORC5_RS12265	COG3615	Tellurite resistance protein tehB
FORC5_RS12275	COG2226	methyltransferase
FORC5_RS12280	COG3961	Belongs to the TPP enzyme family
FORC5_RS12285	COG1846	Transcriptional regulator
FORC5_RS12315	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC5_RS12345	COG2002	toxin-antitoxin pair type II binding
FORC5_RS12355	COG0730	response to heat
FORC5_RS12360	COG0110	maltose O-acetyltransferase activity
FORC5_RS12365	COG1686	Belongs to the peptidase S11 family
FORC5_RS12375	COG2814	Major facilitator Superfamily
FORC5_RS12420	COG2312	Erythromycin esterase
FORC5_RS12425	COG2312	Erythromycin esterase
FORC5_RS12430	COG0741	lytic transglycosylase activity
FORC5_RS12435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS12485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC5_RS12490	COG0768	penicillin binding
FORC5_RS12495	COG1595	DNA-templated transcription, initiation
FORC5_RS12505	COG0768	penicillin binding
FORC5_RS12510	COG0768	penicillin binding
FORC5_RS12520	COG1408	metallophosphoesterase
FORC5_RS12530	COG1131	(ABC) transporter
FORC5_RS12540	COG1309	transcriptional regulator
FORC5_RS12555	COG1960	acyl-CoA dehydrogenase activity
FORC5_RS12560	COG0439	Biotin carboxylase
FORC5_RS12565	COG0511	ligase activity, forming carbon-carbon bonds
FORC5_RS12570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC5_RS12575	COG1024	Enoyl-CoA hydratase
FORC5_RS12580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC5_RS12585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC5_RS12605	COG0572	uridine kinase
FORC5_RS12620	COG1686	Belongs to the peptidase S11 family
FORC5_RS12645	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC5_RS12660	COG3227	Zinc metalloprotease (Elastase)
FORC5_RS12665	COG2207	Transcriptional regulator
FORC5_RS12695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC5_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS12710	COG1733	regulation of RNA biosynthetic process
FORC5_RS12730	COG1942	4-Oxalocrotonate Tautomerase
FORC5_RS12735	COG0583	DNA-binding transcription factor activity
FORC5_RS12755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS12765	COG2368	4-hydroxyphenylacetate
FORC5_RS12780	COG1063	alcohol dehydrogenase
FORC5_RS12790	COG2323	membrane
FORC5_RS12795	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC5_RS12820	COG3773	Cell wall hydrolase
FORC5_RS12830	COG0745	RESPONSE REGULATOR receiver
FORC5_RS12835	COG2205	protein histidine kinase activity
FORC5_RS12845	COG0488	(ABC) transporter
FORC5_RS12865	COG0825	malonyl-CoA metabolic process
FORC5_RS12875	COG1136	(ABC) transporter
FORC5_RS12880	COG0577	efflux transmembrane transporter activity
FORC5_RS12900	COG0460	homoserine dehydrogenase
FORC5_RS12905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS12915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC5_RS12940	COG0582	viral genome integration into host DNA
FORC5_RS12960	COG1396	sequence-specific DNA binding
FORC5_RS12985	COG2002	toxin-antitoxin pair type II binding
FORC5_RS13020	COG0662	Cupin 2, conserved barrel domain protein
FORC5_RS13050	COG0582	viral genome integration into host DNA
FORC5_RS13180	COG4824	toxin secretion phage lysis holin
FORC5_RS13185	COG3409	Peptidoglycan-binding domain 1 protein
FORC5_RS13185	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS13185	COG1388	LysM domain
FORC5_RS13240	COG2124	cytochrome p450
FORC5_RS13275	COG0561	phosphatase activity
FORC5_RS13280	COG5002	protein histidine kinase activity
FORC5_RS13285	COG0768	penicillin binding
FORC5_RS13295	COG1819	glycosyl
FORC5_RS13300	COG1794	racemase activity, acting on amino acids and derivatives
FORC5_RS13320	COG2205	protein histidine kinase activity
FORC5_RS13360	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC5_RS13365	COG0604	alcohol dehydrogenase
FORC5_RS13370	COG0671	phosphoesterase, PA-phosphatase related
FORC5_RS13375	COG0768	penicillin binding
FORC5_RS13430	COG2814	Major facilitator Superfamily
FORC5_RS13435	COG0789	Transcriptional regulator
FORC5_RS13435	COG4978	Transcriptional regulator
FORC5_RS13455	COG0584	glycerophosphoryl diester phosphodiesterase
FORC5_RS13475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS13480	COG0697	spore germination
FORC5_RS13515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC5_RS13525	COG2223	nitrite transmembrane transporter activity
FORC5_RS13540	COG0592	DNA-directed DNA polymerase activity
FORC5_RS13560	COG3878	Protein conserved in bacteria
FORC5_RS13570	COG3693	PFAM glycoside hydrolase, family 10
FORC5_RS13570	COG2382	esterase
FORC5_RS13570	COG3507	Belongs to the glycosyl hydrolase 43 family
FORC5_RS13585	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC5_RS13625	COG0322	excinuclease ABC activity
FORC5_RS13665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC5_RS13695	COG0745	RESPONSE REGULATOR receiver
FORC5_RS13700	COG5002	protein histidine kinase activity
FORC5_RS13715	COG1136	(ABC) transporter
FORC5_RS13720	COG0577	efflux transmembrane transporter activity
FORC5_RS13725	COG1073	alpha beta
FORC5_RS13730	COG0657	acetylesterase activity
FORC5_RS13735	COG0076	glutamate decarboxylase activity
FORC5_RS13750	COG1523	belongs to the glycosyl hydrolase 13 family
FORC5_RS13755	COG3227	Zinc metalloprotease (Elastase)
FORC5_RS13760	COG0737	Belongs to the 5'-nucleotidase family
FORC5_RS13775	COG0201	protein transport
FORC5_RS13780	COG0697	spore germination
FORC5_RS13785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS13795	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC5_RS13825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS13840	COG2959	enzyme of heme biosynthesis
FORC5_RS13880	COG1309	transcriptional regulator
FORC5_RS13910	COG3284	Transcriptional regulator
FORC5_RS13930	COG1349	DNA-binding transcription factor activity
FORC5_RS13945	COG1959	2 iron, 2 sulfur cluster binding
FORC5_RS13960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC5_RS13965	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC5_RS13970	COG0022	dehydrogenase e1 component
FORC5_RS13975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC5_RS13985	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS13990	COG0456	acetyltransferase
FORC5_RS13990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC5_RS14030	COG4176	ABC-type proline glycine betaine transport system permease component
FORC5_RS14035	COG0517	IMP dehydrogenase activity
FORC5_RS14035	COG4175	Glycine betaine
FORC5_RS14070	COG3397	chitin binding
FORC5_RS14075	COG1819	glycosyl
FORC5_RS14090	COG2205	protein histidine kinase activity
FORC5_RS14095	COG2226	methyltransferase
FORC5_RS14100	COG2315	Protein conserved in bacteria
FORC5_RS14140	COG3973	AAA domain
FORC5_RS14155	COG0514	ATP-dependent DNA helicase (RecQ)
FORC5_RS14190	COG4637	Psort location Cytoplasmic, score
FORC5_RS14205	COG3397	chitin binding
FORC5_RS14220	COG1162	GTPase activity
FORC5_RS14225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC5_RS14230	COG1115	amino acid carrier protein
FORC5_RS14235	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS14240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC5_RS14250	COG3938	Belongs to the proline racemase family
FORC5_RS14255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC5_RS14300	COG1078	dGTPase activity
FORC5_RS14305	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS14315	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC5_RS14325	COG4166	transmembrane transport
FORC5_RS14335	COG4948	Mandelate Racemase Muconate Lactonizing
FORC5_RS14350	COG0667	Aldo Keto reductase
FORC5_RS14395	COG3850	Histidine kinase
FORC5_RS14395	COG5002	protein histidine kinase activity
FORC5_RS14400	COG0745	RESPONSE REGULATOR receiver
FORC5_RS14435	COG1164	Oligoendopeptidase f
FORC5_RS14440	COG1307	EDD domain protein, DegV family
FORC5_RS14480	COG2814	Major facilitator Superfamily
FORC5_RS14490	COG1664	Polymer-forming cytoskeletal
FORC5_RS14495	COG0789	Transcriptional regulator
FORC5_RS14500	COG4533	DNA binding
FORC5_RS14505	COG2814	Major facilitator Superfamily
FORC5_RS14505	COG0477	Major facilitator Superfamily
FORC5_RS14525	COG2261	transglycosylase associated protein
FORC5_RS14540	COG2226	methyltransferase
FORC5_RS14575	COG0436	Aminotransferase
FORC5_RS14580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC5_RS14590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FORC5_RS14605	COG1131	(ABC) transporter
FORC5_RS14660	COG0628	permease
FORC5_RS14675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC5_RS14680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC5_RS14685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC5_RS14725	COG2746	aminoglycoside 3-N-acetyltransferase activity
FORC5_RS14735	COG0697	spore germination
FORC5_RS14740	COG2318	DinB family
FORC5_RS14760	COG4912	Dna alkylation repair
FORC5_RS14765	COG0346	lactoylglutathione lyase activity
FORC5_RS14780	COG0861	Integral membrane protein TerC family
FORC5_RS14785	COG1368	sulfuric ester hydrolase activity
FORC5_RS14790	COG0488	(ABC) transporter
FORC5_RS14795	COG1033	growth of symbiont in host cell
FORC5_RS14795	COG2409	Drug exporters of the RND superfamily
FORC5_RS14800	COG1309	transcriptional regulator
FORC5_RS14815	COG0287	Prephenate dehydrogenase
FORC5_RS14830	COG1605	Chorismate mutase
FORC5_RS14830	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC5_RS14875	COG3584	3D domain protein
FORC5_RS14875	COG1388	LysM domain
FORC5_RS14885	COG0346	lactoylglutathione lyase activity
FORC5_RS14900	COG1309	transcriptional regulator
FORC5_RS14910	COG1595	DNA-templated transcription, initiation
FORC5_RS14935	COG1879	ABC-type sugar transport system periplasmic component
FORC5_RS14940	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC5_RS14945	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC5_RS14955	COG2390	Transcriptional regulator
FORC5_RS14960	COG1070	Carbohydrate kinase
FORC5_RS14985	COG2329	Antibiotic biosynthesis monooxygenase
FORC5_RS15005	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS15020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC5_RS15025	COG4187	Peptidase family M20/M25/M40
FORC5_RS15030	COG1414	Transcriptional regulator
FORC5_RS15035	COG0833	amino acid
FORC5_RS15045	COG3239	Fatty acid desaturase
FORC5_RS15055	COG2720	vancomycin resistance protein
FORC5_RS15060	COG1785	Belongs to the alkaline phosphatase family
FORC5_RS15070	COG3655	Transcriptional regulator
FORC5_RS15090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS15095	COG0346	lactoylglutathione lyase activity
FORC5_RS15120	COG0714	Associated with various cellular activities
FORC5_RS15145	COG0463	Glycosyl transferase, family 2
FORC5_RS15175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC5_RS15180	COG0753	catalase activity
FORC5_RS15220	COG0714	Associated with various cellular activities
FORC5_RS15280	COG2801	Transposase and inactivated derivatives
FORC5_RS15295	COG0778	Nitroreductase
FORC5_RS15300	COG1846	Transcriptional regulator
FORC5_RS15320	COG4884	unkown
FORC5_RS15320	COG3831	ATPase activity
FORC5_RS15345	COG0456	acetyltransferase
FORC5_RS15360	COG0697	spore germination
FORC5_RS15365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS15415	COG0730	response to heat
FORC5_RS15425	COG0833	amino acid
FORC5_RS15435	COG4335	DNA alkylation repair
FORC5_RS15445	COG5002	protein histidine kinase activity
FORC5_RS15450	COG0745	RESPONSE REGULATOR receiver
FORC5_RS15460	COG1136	(ABC) transporter
FORC5_RS15460	COG0577	efflux transmembrane transporter activity
FORC5_RS15500	COG0768	penicillin binding
FORC5_RS15530	COG1984	allophanate hydrolase subunit 2
FORC5_RS15535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC5_RS15540	COG1414	Transcriptional regulator
FORC5_RS15555	COG0640	Transcriptional regulator
FORC5_RS15565	COG1960	acyl-CoA dehydrogenase activity
FORC5_RS15580	COG3314	Sporulation integral membrane protein YlbJ
FORC5_RS15600	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FORC5_RS15625	COG0574	Belongs to the PEP-utilizing enzyme family
FORC5_RS15625	COG3848	Pyruvate phosphate dikinase
FORC5_RS15630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS15650	COG1063	alcohol dehydrogenase
FORC5_RS15655	COG1027	Aspartate ammonia-lyase
FORC5_RS15660	COG0252	asparaginase activity
FORC5_RS15665	COG1396	sequence-specific DNA binding
FORC5_RS15690	COG5002	protein histidine kinase activity
FORC5_RS15715	COG2207	Transcriptional regulator
FORC5_RS15725	COG0322	excinuclease ABC activity
FORC5_RS15730	COG0531	amino acid
FORC5_RS15735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC5_RS15745	COG0531	amino acid
FORC5_RS15750	COG0697	spore germination
FORC5_RS15755	COG0784	Response regulator, receiver
FORC5_RS15760	COG4191	Histidine kinase
FORC5_RS15770	COG1115	amino acid carrier protein
FORC5_RS15795	COG0737	Belongs to the 5'-nucleotidase family
FORC5_RS15800	COG2267	carboxylic ester hydrolase activity
FORC5_RS15805	COG1335	isochorismatase
FORC5_RS15825	COG0583	DNA-binding transcription factor activity
FORC5_RS15835	COG0598	Magnesium transport protein CorA
FORC5_RS15855	COG1073	alpha beta
FORC5_RS15875	COG0415	Belongs to the DNA photolyase family
FORC5_RS15885	COG2814	Major facilitator Superfamily
FORC5_RS15895	COG0657	acetylesterase activity
FORC5_RS15900	COG0288	reversible hydration of carbon dioxide
FORC5_RS15910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC5_RS15915	COG5609	conserved protein (DUF2294)
FORC5_RS15925	COG0456	acetyltransferase
FORC5_RS15930	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC5_RS15940	COG0798	PFAM Bile acid sodium symporter
FORC5_RS15945	COG0346	lactoylglutathione lyase activity
FORC5_RS15950	COG0640	Transcriptional regulator
FORC5_RS15960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC5_RS15960	COG3320	Male sterility
FORC5_RS15965	COG1309	transcriptional regulator
FORC5_RS15980	COG0346	lactoylglutathione lyase activity
FORC5_RS16005	COG0745	RESPONSE REGULATOR receiver
FORC5_RS16010	COG5002	protein histidine kinase activity
FORC5_RS16010	COG3850	Histidine kinase
FORC5_RS16045	COG0277	FAD linked oxidase domain protein
FORC5_RS16055	COG1136	(ABC) transporter
FORC5_RS16090	COG2814	Major facilitator Superfamily
FORC5_RS16110	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC5_RS16130	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC5_RS16150	COG0577	efflux transmembrane transporter activity
FORC5_RS16170	COG5002	protein histidine kinase activity
FORC5_RS16170	COG3850	Histidine kinase
FORC5_RS16180	COG2364	Membrane
FORC5_RS16185	COG1846	Transcriptional regulator
FORC5_RS16190	COG0456	acetyltransferase
FORC5_RS16195	COG2808	Putative FMN-binding domain
FORC5_RS16200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS16230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC5_RS16270	COG3409	Peptidoglycan-binding domain 1 protein
FORC5_RS16270	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS16320	COG5444	nuclease activity
FORC5_RS16405	COG1876	peptidase activity
FORC5_RS16410	COG2843	Capsule synthesis protein
FORC5_RS16420	COG0477	Major facilitator Superfamily
FORC5_RS16435	COG1846	Transcriptional regulator
FORC5_RS16440	COG2814	Major facilitator Superfamily
FORC5_RS16455	COG2031	fatty acid transporter
FORC5_RS16465	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC5_RS16520	COG1288	antiporter activity
FORC5_RS16525	COG2356	endonuclease I
FORC5_RS16545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC5_RS16565	COG1733	regulation of RNA biosynthetic process
FORC5_RS16570	COG0778	Nitroreductase
FORC5_RS16580	COG0469	pyruvate kinase activity
FORC5_RS16600	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS16610	COG1131	(ABC) transporter
FORC5_RS16635	COG1011	Hydrolase
FORC5_RS16640	COG2365	Tyrosine phosphatase family
FORC5_RS16675	COG0628	permease
FORC5_RS16705	COG0500	methyltransferase
FORC5_RS16745	COG1253	flavin adenine dinucleotide binding
FORC5_RS16750	COG0789	Transcriptional regulator
FORC5_RS16760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC5_RS16790	COG0697	spore germination
FORC5_RS16800	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC5_RS16805	COG3813	Protein conserved in bacteria
FORC5_RS16810	COG2706	6-phosphogluconolactonase activity
FORC5_RS16815	COG1070	Carbohydrate kinase
FORC5_RS16825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC5_RS16830	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC5_RS16835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC5_RS16840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC5_RS16875	COG0814	amino acid
FORC5_RS16900	COG2188	Transcriptional regulator
FORC5_RS16905	COG0673	inositol 2-dehydrogenase activity
FORC5_RS16925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS16950	COG0384	phenazine biosynthesis protein PhzF
FORC5_RS16960	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS16975	COG0318	PFAM AMP-dependent synthetase and ligase
FORC5_RS16980	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC5_RS16985	COG1733	regulation of RNA biosynthetic process
FORC5_RS17010	COG1191	sigma factor activity
FORC5_RS17065	COG3209	COG3209 Rhs family protein
FORC5_RS17075	COG1151	hydroxylamine reductase activity
FORC5_RS17105	COG2072	flavoprotein involved in K transport
FORC5_RS17140	COG1113	amino acid transport
FORC5_RS17145	COG2814	Major facilitator Superfamily
FORC5_RS17180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FORC5_RS17185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC5_RS17195	COG1247	-acetyltransferase
FORC5_RS17200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS17205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS17210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS17235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS17250	COG0583	DNA-binding transcription factor activity
FORC5_RS17280	COG1193	negative regulation of DNA recombination
FORC5_RS17290	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC5_RS17295	COG1164	Oligoendopeptidase f
FORC5_RS17325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC5_RS17350	COG0584	glycerophosphoryl diester phosphodiesterase
FORC5_RS17365	COG0640	Transcriptional regulator
FORC5_RS17370	COG0604	alcohol dehydrogenase
FORC5_RS17385	COG0457	Tetratricopeptide repeat
FORC5_RS17395	COG0277	FAD linked oxidase domain protein
FORC5_RS17415	COG1183	phosphatidylcholine synthase activity
FORC5_RS17425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS17425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS17430	COG1252	NADH dehydrogenase
FORC5_RS17440	COG0823	Involved in the tonB-independent uptake of proteins
FORC5_RS17445	COG3397	chitin binding
FORC5_RS17455	COG0697	spore germination
FORC5_RS17475	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC5_RS17485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC5_RS17495	COG0457	Tetratricopeptide repeat
FORC5_RS17555	COG0488	(ABC) transporter
FORC5_RS17585	COG3852	Histidine kinase
FORC5_RS17595	COG1285	pathogenesis
FORC5_RS17605	COG2514	catechol 2,3-dioxygenase activity
FORC5_RS17610	COG2720	vancomycin resistance protein
FORC5_RS17650	COG0716	FMN binding
FORC5_RS17660	COG0494	nUDIX hydrolase
FORC5_RS17680	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS17690	COG0165	Argininosuccinate lyase
FORC5_RS17705	COG4145	pantothenate transmembrane transporter activity
FORC5_RS17715	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS17720	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS17730	COG1657	PFAM Prenyltransferase squalene oxidase
FORC5_RS17735	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FORC5_RS17740	COG2962	Rard protein
FORC5_RS17745	COG3326	Membrane
FORC5_RS17760	COG0489	protein tyrosine kinase activity
FORC5_RS17770	COG0314	molybdopterin synthase activity
FORC5_RS17775	COG0303	'Molybdopterin
FORC5_RS17780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC5_RS17785	COG2116	formate transmembrane transporter activity
FORC5_RS17795	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC5_RS17800	COG5609	conserved protein (DUF2294)
FORC5_RS17805	COG2427	Protein of unknown function (DUF1641)
FORC5_RS17810	COG3383	formate dehydrogenase (NAD+) activity
FORC5_RS17820	COG0697	spore germination
FORC5_RS17835	COG0531	amino acid
FORC5_RS17870	COG2226	methyltransferase
FORC5_RS17875	COG4166	transmembrane transport
FORC5_RS17880	COG4166	transmembrane transport
FORC5_RS17885	COG4166	transmembrane transport
FORC5_RS17890	COG1301	dicarboxylic acid transport
FORC5_RS17895	COG1316	TRANSCRIPTIONal
FORC5_RS17905	COG1595	DNA-templated transcription, initiation
FORC5_RS17915	COG1131	(ABC) transporter
FORC5_RS17925	COG0673	inositol 2-dehydrogenase activity
FORC5_RS17930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC5_RS17935	COG0187	DNA topoisomerase II activity
FORC5_RS17945	COG1832	CoA-binding protein
FORC5_RS17950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC5_RS17955	COG0745	RESPONSE REGULATOR receiver
FORC5_RS17975	COG4841	protein insertion into membrane
FORC5_RS17980	COG0824	Thioesterase
FORC5_RS18010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC5_RS18025	COG1122	ATPase activity
FORC5_RS18030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC5_RS18060	COG2211	Major facilitator Superfamily
FORC5_RS18070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC5_RS18085	COG0183	Belongs to the thiolase family
FORC5_RS18090	COG0318	PFAM AMP-dependent synthetase and ligase
FORC5_RS18095	COG1268	BioY protein
FORC5_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
FORC5_RS18140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS18150	COG5002	protein histidine kinase activity
FORC5_RS18155	COG0400	carboxylic ester hydrolase activity
FORC5_RS18160	COG0346	lactoylglutathione lyase activity
FORC5_RS18165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC5_RS18175	COG0069	glutamate synthase activity
FORC5_RS18180	COG1902	pentaerythritol trinitrate reductase activity
FORC5_RS18185	COG1329	Transcriptional regulator
FORC5_RS18190	COG0010	Belongs to the arginase family
FORC5_RS18245	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC5_RS18250	COG0785	Cytochrome C biogenesis protein
FORC5_RS18260	COG1473	amidohydrolase
FORC5_RS18270	COG1131	(ABC) transporter
FORC5_RS18285	COG0583	DNA-binding transcription factor activity
FORC5_RS18295	COG1346	cytolysis
FORC5_RS18310	COG0730	response to heat
FORC5_RS18335	COG1132	(ABC) transporter
FORC5_RS18340	COG1132	(ABC) transporter
FORC5_RS18365	COG3639	organic phosphonate transmembrane transporter activity
FORC5_RS18375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC5_RS18380	COG0737	Belongs to the 5'-nucleotidase family
FORC5_RS18390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC5_RS18410	COG1695	Transcriptional regulator
FORC5_RS18420	COG1388	LysM domain
FORC5_RS18420	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS18420	COG3409	Peptidoglycan-binding domain 1 protein
FORC5_RS18425	COG0739	heme binding
FORC5_RS18430	COG0741	lytic transglycosylase activity
FORC5_RS18460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC5_RS18465	COG0174	glutamine synthetase
FORC5_RS18470	COG0789	Transcriptional regulator
FORC5_RS18475	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FORC5_RS18480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC5_RS18485	COG2860	membrane
FORC5_RS18495	COG0464	growth
FORC5_RS18525	COG1388	LysM domain
FORC5_RS18525	COG3584	3D domain protein
FORC5_RS18530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC5_RS18530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC5_RS18530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC5_RS18535	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC5_RS18540	COG1349	DNA-binding transcription factor activity
FORC5_RS18545	COG1979	alcohol dehydrogenase
FORC5_RS18550	COG2322	membrane
FORC5_RS18565	COG1113	amino acid transport
FORC5_RS18575	COG1408	metallophosphoesterase
FORC5_RS18580	COG2116	formate transmembrane transporter activity
FORC5_RS18595	COG2217	Heavy metal translocating P-type atpase
FORC5_RS18600	COG2608	mercury ion transmembrane transporter activity
FORC5_RS18605	COG1937	Protein conserved in bacteria
FORC5_RS18615	COG2819	hydrolase of the alpha beta superfamily
FORC5_RS18620	COG1120	ATPase activity
FORC5_RS18625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS18630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS18635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS18640	COG2169	Transcriptional regulator
FORC5_RS18645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC5_RS18650	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC5_RS18660	COG2364	Membrane
FORC5_RS18675	COG2267	carboxylic ester hydrolase activity
FORC5_RS18680	COG5001	Diguanylate cyclase
FORC5_RS18680	COG3300	MHYT domain
FORC5_RS18720	COG1346	cytolysis
FORC5_RS18730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC5_RS18740	COG2188	Transcriptional regulator
FORC5_RS18745	COG2723	6-phospho-beta-galactosidase activity
FORC5_RS18755	COG1404	Belongs to the peptidase S8 family
FORC5_RS18760	COG3773	Cell wall hydrolase
FORC5_RS18770	COG1368	sulfuric ester hydrolase activity
FORC5_RS18775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC5_RS18800	COG4550	Control of competence regulator ComK, YlbF/YmcA
FORC5_RS18810	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC5_RS18815	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC5_RS18815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC5_RS18825	COG2359	stage V sporulation protein S
FORC5_RS18830	COG1692	metallophosphoesterase
FORC5_RS18850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC5_RS18855	COG1426	Protein conserved in bacteria
FORC5_RS18870	COG0300	oxidoreductase activity
FORC5_RS18875	COG0612	Peptidase, M16
FORC5_RS18880	COG0612	Peptidase, M16
FORC5_RS18885	COG1079	Belongs to the binding-protein-dependent transport system permease family
FORC5_RS18890	COG4603	Belongs to the binding-protein-dependent transport system permease family
FORC5_RS18895	COG3845	ABC transporter
FORC5_RS18900	COG1744	ABC transporter substrate-binding protein PnrA-like
FORC5_RS18905	COG2188	Transcriptional regulator
FORC5_RS18920	COG0740	serine-type endopeptidase activity
FORC5_RS18925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC5_RS18940	COG0527	aspartate kinase activity
FORC5_RS18945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC5_RS18950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC5_RS18955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC5_RS18960	COG1873	PFAM PRC-barrel domain
FORC5_RS18965	COG0612	Peptidase, M16
FORC5_RS18970	COG0726	polysaccharide deacetylase
FORC5_RS18985	COG0196	riboflavin kinase activity
FORC5_RS18995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC5_RS19000	COG1550	Protein conserved in bacteria
FORC5_RS19010	COG1358	cellular component organization or biogenesis
FORC5_RS19015	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FORC5_RS19020	COG0195	Participates in both transcription termination and antitermination
FORC5_RS19040	COG0750	zinc metalloprotease
FORC5_RS19050	COG4589	Belongs to the CDS family
FORC5_RS19095	COG4974	Belongs to the 'phage' integrase family
FORC5_RS19105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC5_RS19110	COG0758	DNA mediated transformation
FORC5_RS19115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC5_RS19155	COG1837	Belongs to the UPF0109 family
FORC5_RS19165	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC5_RS19175	COG0552	protein localization to endoplasmic reticulum
FORC5_RS19180	COG1196	nuclear chromosome segregation
FORC5_RS19190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC5_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS19200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC5_RS19215	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC5_RS19220	COG1461	Dihydroxyacetone kinase
FORC5_RS19225	COG1302	Protein conserved in bacteria
FORC5_RS19240	COG1564	THIamine pyrophosphokinase
FORC5_RS19245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC5_RS19255	COG2815	serine threonine protein kinase
FORC5_RS19255	COG0515	serine threonine protein kinase
FORC5_RS19260	COG0631	protein serine/threonine phosphatase activity
FORC5_RS19270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC5_RS19270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC5_RS19285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC5_RS19290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC5_RS19310	COG1561	YicC-like family, N-terminal region
FORC5_RS19315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC5_RS19325	COG0006	proline dipeptidase activity
FORC5_RS19340	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC5_RS19400	COG0564	pseudouridine synthase activity
FORC5_RS19420	COG3599	regulation of cell shape
FORC5_RS19425	COG2302	S4 RNA-binding domain
FORC5_RS19430	COG0762	integral membrane protein
FORC5_RS19440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC5_RS19450	COG1873	PFAM PRC-barrel domain
FORC5_RS19455	COG1191	sigma factor activity
FORC5_RS19460	COG1191	sigma factor activity
FORC5_RS19470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC5_RS19475	COG0849	cell division
FORC5_RS19495	COG0772	Belongs to the SEDS family
FORC5_RS19515	COG0768	penicillin binding
FORC5_RS19520	COG0768	penicillin binding
FORC5_RS19540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC5_RS19555	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC5_RS19560	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC5_RS19570	COG3480	Lon protease (S16) C-terminal proteolytic domain
FORC5_RS19575	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC5_RS19580	COG3314	Sporulation integral membrane protein YlbJ
FORC5_RS19590	COG0742	ribosomal rna small subunit methyltransferase
FORC5_RS19605	COG3679	Belongs to the UPF0342 family
FORC5_RS19610	COG0406	alpha-ribazole phosphatase activity
FORC5_RS19625	COG2340	Cysteine-rich secretory protein family
FORC5_RS19640	COG3336	cytochrome c oxidase
FORC5_RS19675	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FORC5_RS19680	COG0772	Belongs to the SEDS family
FORC5_RS19690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FORC5_RS19695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC5_RS19705	COG4896	Protein conserved in bacteria
FORC5_RS19720	COG1217	gtp-binding protein TYPA
FORC5_RS19730	COG0483	inositol monophosphate 1-phosphatase activity
FORC5_RS19750	COG1982	Orn Lys Arg decarboxylase major
FORC5_RS19800	COG0022	dehydrogenase e1 component
FORC5_RS19805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC5_RS19820	COG0561	phosphatase activity
FORC5_RS19830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC5_RS19835	COG0569	domain protein
FORC5_RS19855	COG0583	DNA-binding transcription factor activity
FORC5_RS19860	COG0517	IMP dehydrogenase activity
FORC5_RS19870	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FORC5_RS19880	COG4703	Protein of unknown function (DUF1797)
FORC5_RS19895	COG2200	EAL domain
FORC5_RS19900	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS19905	COG1408	metallophosphoesterase
FORC5_RS19950	COG2814	Major facilitator Superfamily
FORC5_RS19975	COG3209	COG3209 Rhs family protein
FORC5_RS19985	COG2205	protein histidine kinase activity
FORC5_RS19995	COG0436	Aminotransferase
FORC5_RS20000	COG1609	Transcriptional regulator
FORC5_RS20005	COG3833	ABC-type maltose transport systems, permease component
FORC5_RS20010	COG1175	transmembrane transport
FORC5_RS20015	COG2182	Extracellular solute-binding protein
FORC5_RS20025	COG0366	Alpha amylase catalytic
FORC5_RS20030	COG3842	ATPase activity
FORC5_RS20070	COG0183	Belongs to the thiolase family
FORC5_RS20105	COG1695	Transcriptional regulator
FORC5_RS20110	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS20130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC5_RS20135	COG0436	Aminotransferase
FORC5_RS20170	COG2084	Dehydrogenase
FORC5_RS20180	COG2199	diguanylate cyclase activity
FORC5_RS20185	COG0778	Nitroreductase
FORC5_RS20210	COG1263	PTS System
FORC5_RS20210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC5_RS20210	COG2190	(PTS) system
FORC5_RS20215	COG3711	transcriptional antiterminator
FORC5_RS20225	COG2188	Transcriptional regulator
FORC5_RS20235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC5_RS20265	COG1547	Domain of unknown function (DUF309)
FORC5_RS20270	COG0456	acetyltransferase
FORC5_RS20275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC5_RS20280	COG4086	secreted protein
FORC5_RS20285	COG0561	phosphatase activity
FORC5_RS20290	COG0697	spore germination
FORC5_RS20305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC5_RS20330	COG0733	neurotransmitter:sodium symporter activity
FORC5_RS20350	COG1686	Belongs to the peptidase S11 family
FORC5_RS20355	COG1725	Transcriptional regulator
FORC5_RS20360	COG1131	(ABC) transporter
FORC5_RS20380	COG1846	Transcriptional regulator
FORC5_RS20395	COG0598	Magnesium transport protein CorA
FORC5_RS20420	COG4974	Belongs to the 'phage' integrase family
FORC5_RS20430	COG0735	belongs to the Fur family
FORC5_RS20435	COG1300	Membrane
FORC5_RS20455	COG0667	Aldo Keto reductase
FORC5_RS20460	COG0656	L-ascorbic acid biosynthetic process
FORC5_RS20465	COG0456	acetyltransferase
FORC5_RS20465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC5_RS20475	COG0737	Belongs to the 5'-nucleotidase family
FORC5_RS20475	COG4085	toxin activity
FORC5_RS20475	COG1525	nuclease
FORC5_RS20485	COG0596	Alpha beta hydrolase
FORC5_RS20490	COG2056	Na+-H+ antiporter family
FORC5_RS20495	COG1609	Transcriptional regulator
FORC5_RS20500	COG0456	acetyltransferase
FORC5_RS20505	COG1073	alpha beta
FORC5_RS20520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC5_RS20520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC5_RS20525	COG0307	riboflavin synthase, alpha
FORC5_RS20555	COG1073	alpha beta
FORC5_RS20555	COG2226	methyltransferase
FORC5_RS20570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC5_RS20580	COG1757	Na H antiporter
FORC5_RS20585	COG0737	Belongs to the 5'-nucleotidase family
FORC5_RS20595	COG1522	sequence-specific DNA binding
FORC5_RS20640	COG0300	oxidoreductase activity
FORC5_RS20645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS20650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC5_RS20655	COG1760	l-serine dehydratase
FORC5_RS20660	COG1760	l-serine dehydratase
FORC5_RS20690	COG1285	pathogenesis
FORC5_RS20700	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC5_RS20705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS20720	COG1376	ErfK ybiS ycfS ynhG family protein
FORC5_RS20725	COG4129	membrane
FORC5_RS20730	COG1126	abc transporter atp-binding protein
FORC5_RS20735	COG0765	amino acid transport
FORC5_RS20740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC5_RS20755	COG2816	NAD+ diphosphatase activity
FORC5_RS20760	COG2323	membrane
FORC5_RS20765	COG0772	Belongs to the SEDS family
FORC5_RS20775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC5_RS20780	COG0022	dehydrogenase e1 component
FORC5_RS20785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC5_RS20790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC5_RS20805	COG0280	phosphate acetyltransferase
FORC5_RS20815	COG3829	transcription factor binding
FORC5_RS20815	COG3290	protein histidine kinase activity
FORC5_RS20825	COG0584	glycerophosphoryl diester phosphodiesterase
FORC5_RS20830	COG3093	addiction module antidote protein HigA
FORC5_RS20850	COG0750	zinc metalloprotease
FORC5_RS20855	COG0497	DNA recombination
FORC5_RS20865	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FORC5_RS20875	COG0142	geranyltranstransferase activity
FORC5_RS20900	COG1302	Protein conserved in bacteria
FORC5_RS20905	COG0439	Biotin carboxylase
FORC5_RS20910	COG0511	ligase activity, forming carbon-carbon bonds
FORC5_RS20955	COG3854	ATPases associated with a variety of cellular activities
FORC5_RS20980	COG0006	proline dipeptidase activity
FORC5_RS20995	COG3872	metal-dependent enzyme
FORC5_RS21005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC5_RS21020	COG1695	Transcriptional regulator
FORC5_RS21040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS21050	COG1609	Transcriptional regulator
FORC5_RS21060	COG2076	Multidrug Resistance protein
FORC5_RS21065	COG2076	Multidrug Resistance protein
FORC5_RS21100	COG1131	(ABC) transporter
FORC5_RS21105	COG1725	Transcriptional regulator
FORC5_RS21135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC5_RS21200	COG1459	type II secretion system
FORC5_RS21205	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC5_RS21260	COG0646	methionine synthase
FORC5_RS21260	COG1410	methionine synthase
FORC5_RS21265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC5_RS21265	COG0646	methionine synthase
FORC5_RS21270	COG0626	cystathionine gamma-synthase activity
FORC5_RS21275	COG0626	cystathionine gamma-synthase activity
FORC5_RS21295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS21305	COG1940	carbohydrate kinase activity
FORC5_RS21310	COG4483	Protein conserved in bacteria
FORC5_RS21315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC5_RS21320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC5_RS21325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC5_RS21330	COG0704	Plays a role in the regulation of phosphate uptake
FORC5_RS21340	COG0573	inorganic phosphate transmembrane transporter activity
FORC5_RS21345	COG0573	inorganic phosphate transmembrane transporter activity
FORC5_RS21350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC5_RS21355	COG0768	penicillin binding
FORC5_RS21360	COG0477	Major facilitator Superfamily
FORC5_RS21365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC5_RS21375	COG5521	maltodextrose utilization protein MalA
FORC5_RS21390	COG0735	belongs to the Fur family
FORC5_RS21395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC5_RS21400	COG1121	(ABC) transporter
FORC5_RS21405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS21435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC5_RS21440	COG2384	SAM-dependent methyltransferase
FORC5_RS21450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC5_RS21455	COG0358	DNA primase activity
FORC5_RS21470	COG0517	IMP dehydrogenase activity
FORC5_RS21485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC5_RS21490	COG0295	cytidine deaminase activity
FORC5_RS21495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC5_RS21505	COG1480	7TM receptor with intracellular HD hydrolase
FORC5_RS21510	COG1702	phosphate starvation-inducible protein PhoH
FORC5_RS21530	COG1610	YqeY-like protein
FORC5_RS21535	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC5_RS21540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC5_RS21545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC5_RS21575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC5_RS21580	COG1733	regulation of RNA biosynthetic process
FORC5_RS21605	COG1466	dna polymerase III delta subunit
FORC5_RS21615	COG0658	competence protein
FORC5_RS21615	COG2333	competence protein COMEC
FORC5_RS21620	COG2131	deaminase
FORC5_RS21625	COG1596	polysaccharide export
FORC5_RS21625	COG1555	photosystem II stabilization
FORC5_RS21630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC5_RS21635	COG2226	methyltransferase
FORC5_RS21640	COG0799	negative regulation of ribosome biogenesis
FORC5_RS21645	COG1713	HD superfamily hydrolase involved in NAD metabolism
FORC5_RS21655	COG1534	Rna-binding protein
FORC5_RS21665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC5_RS21670	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FORC5_RS21705	COG0778	Nitroreductase
FORC5_RS21710	COG2357	RelA SpoT domain protein
FORC5_RS21720	COG1785	Belongs to the alkaline phosphatase family
FORC5_RS21730	COG2267	carboxylic ester hydrolase activity
FORC5_RS21765	COG1404	Belongs to the peptidase S8 family
FORC5_RS21770	COG3186	Phenylalanine-4-hydroxylase
FORC5_RS21780	COG2514	catechol 2,3-dioxygenase activity
FORC5_RS21785	COG2259	Doxx family
FORC5_RS21825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS21835	COG1454	alcohol dehydrogenase
FORC5_RS21835	COG1012	belongs to the aldehyde dehydrogenase family
FORC5_RS21840	COG0626	cystathionine gamma-synthase activity
FORC5_RS21845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC5_RS21870	COG0768	penicillin binding
FORC5_RS21890	COG0826	peptidase U32
FORC5_RS21895	COG0826	peptidase U32
FORC5_RS21900	COG4122	O-methyltransferase activity
FORC5_RS21905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC5_RS21935	COG0628	permease
FORC5_RS21955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC5_RS21970	COG1104	cysteine desulfurase activity
FORC5_RS21975	COG1959	2 iron, 2 sulfur cluster binding
FORC5_RS21980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC5_RS21995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC5_RS22020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC5_RS22030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC5_RS22030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FORC5_RS22035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC5_RS22040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC5_RS22040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC5_RS22050	COG2244	polysaccharide biosynthetic process
FORC5_RS22055	COG2323	membrane
FORC5_RS22065	COG1862	Preprotein translocase
FORC5_RS22095	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC5_RS22125	COG0157	Belongs to the NadC ModD family
FORC5_RS22130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC5_RS22135	COG1104	cysteine desulfurase activity
FORC5_RS22140	COG1827	regulation of RNA biosynthetic process
FORC5_RS22145	COG2258	MOSC domain
FORC5_RS22150	COG0077	Prephenate dehydratase
FORC5_RS22155	COG0577	efflux transmembrane transporter activity
FORC5_RS22160	COG0577	efflux transmembrane transporter activity
FORC5_RS22165	COG1136	(ABC) transporter
FORC5_RS22170	COG5002	protein histidine kinase activity
FORC5_RS22175	COG0745	RESPONSE REGULATOR receiver
FORC5_RS22185	COG3290	protein histidine kinase activity
FORC5_RS22195	COG2868	ribosomal protein
FORC5_RS22205	COG1530	ribonuclease E activity
FORC5_RS22210	COG1994	Peptidase M50
FORC5_RS22215	COG0739	heme binding
FORC5_RS22220	COG2894	cell division
FORC5_RS22240	COG1077	Cell shape determining protein MreB Mrl
FORC5_RS22260	COG0285	dihydrofolate synthase activity
FORC5_RS22275	COG1388	LysM domain
FORC5_RS22285	COG0113	porphobilinogen synthase activity
FORC5_RS22290	COG1587	Uroporphyrinogen-III synthase
FORC5_RS22300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC5_RS22310	COG1846	Transcriptional regulator
FORC5_RS22315	COG1764	response to oxidative stress
FORC5_RS22330	COG1067	ATP-dependent peptidase activity
FORC5_RS22330	COG0470	DNA polymerase III
FORC5_RS22380	COG0622	Phosphoesterase
FORC5_RS22395	COG5401	PFAM Sporulation and spore germination
FORC5_RS22415	COG1309	transcriptional regulator
FORC5_RS22425	COG2197	response regulator
FORC5_RS22430	COG2233	PERMEase
FORC5_RS22435	COG0402	S-adenosylhomocysteine deaminase activity
FORC5_RS22440	COG1983	PspC domain protein
FORC5_RS22445	COG1396	sequence-specific DNA binding
FORC5_RS22450	COG0697	spore germination
FORC5_RS22460	COG1959	2 iron, 2 sulfur cluster binding
FORC5_RS22465	COG1668	transmembrane transport
FORC5_RS22470	COG4152	abc transporter atp-binding protein
FORC5_RS22475	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FORC5_RS22480	COG1360	Flagellar Motor Protein
FORC5_RS22485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC5_RS22490	COG1876	peptidase activity
FORC5_RS22495	COG0824	Thioesterase
FORC5_RS22500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC5_RS22505	COG1053	succinate dehydrogenase
FORC5_RS22510	COG2009	succinate dehydrogenase
FORC5_RS22515	COG1719	4-vinyl reductase, 4VR
FORC5_RS22525	COG3118	belongs to the thioredoxin family
FORC5_RS22530	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FORC5_RS22535	COG2086	electron transfer activity
FORC5_RS22540	COG1024	Enoyl-CoA hydratase
FORC5_RS22545	COG1309	transcriptional regulator
FORC5_RS22550	COG0318	PFAM AMP-dependent synthetase and ligase
FORC5_RS22575	COG2318	DinB family
FORC5_RS22605	COG1131	(ABC) transporter
FORC5_RS22610	COG2205	protein histidine kinase activity
FORC5_RS22615	COG0745	RESPONSE REGULATOR receiver
FORC5_RS22625	COG4895	conserved protein (DUF2196)
FORC5_RS22630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC5_RS22640	COG4509	Sortase family
FORC5_RS22645	COG1120	ATPase activity
FORC5_RS22660	COG5386	Cell surface protein
FORC5_RS22670	COG5386	Cell surface protein
FORC5_RS22675	COG1114	Component of the transport system for branched-chain amino acids
FORC5_RS22680	COG1187	pseudouridine synthase activity
FORC5_RS22695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC5_RS22695	COG1796	DNA polymerase
FORC5_RS22700	COG1286	toxin biosynthetic process
FORC5_RS22740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC5_RS22750	COG1418	mRNA catabolic process
FORC5_RS22760	COG2814	Major facilitator Superfamily
FORC5_RS22765	COG1566	PFAM secretion protein HlyD family protein
FORC5_RS22770	COG1309	transcriptional regulator
FORC5_RS22775	COG1363	Peptidase, m42
FORC5_RS22800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC5_RS22815	COG1484	DNA-dependent DNA replication
FORC5_RS22820	COG3611	Membrane attachment protein
FORC5_RS22830	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC5_RS22835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC5_RS22845	COG1971	Probably functions as a manganese efflux pump
FORC5_RS22855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC5_RS22855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC5_RS22860	COG5002	protein histidine kinase activity
FORC5_RS22865	COG0745	RESPONSE REGULATOR receiver
FORC5_RS22880	COG0538	isocitrate dehydrogenase activity
FORC5_RS22885	COG0372	Belongs to the citrate synthase family
FORC5_RS22900	COG0628	permease
FORC5_RS22905	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC5_RS22930	COG1725	Transcriptional regulator
FORC5_RS22935	COG0281	malic enzyme
FORC5_RS22940	COG0587	DNA-directed DNA polymerase activity
FORC5_RS22955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC5_RS22970	COG4109	DRTGG domain
FORC5_RS22985	COG0006	proline dipeptidase activity
FORC5_RS23015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS23020	COG0662	Cupin 2, conserved barrel domain protein
FORC5_RS23035	COG1028	Short-chain dehydrogenase reductase Sdr
FORC5_RS23040	COG0589	response to stress
FORC5_RS23080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS23105	COG0827	DNA restriction-modification system
FORC5_RS23110	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC5_RS23115	COG3874	Sporulation protein YtfJ
FORC5_RS23130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FORC5_RS23140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC5_RS23155	COG1104	cysteine desulfurase activity
FORC5_RS23165	COG0583	DNA-binding transcription factor activity
FORC5_RS23170	COG0697	spore germination
FORC5_RS23175	COG1309	transcriptional regulator
FORC5_RS23180	COG1956	GAF domain-containing protein
FORC5_RS23185	COG0626	cystathionine gamma-synthase activity
FORC5_RS23240	COG0110	maltose O-acetyltransferase activity
FORC5_RS23245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC5_RS23250	COG0454	-acetyltransferase
FORC5_RS23255	COG0517	IMP dehydrogenase activity
FORC5_RS23260	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC5_RS23275	COG0745	RESPONSE REGULATOR receiver
FORC5_RS23280	COG5002	protein histidine kinase activity
FORC5_RS23285	COG0666	response to abiotic stimulus
FORC5_RS23320	COG1609	Transcriptional regulator
FORC5_RS23330	COG1605	Chorismate mutase
FORC5_RS23330	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC5_RS23335	COG4851	CamS sex pheromone cAM373 precursor
FORC5_RS23350	COG2309	aminopeptidase activity
FORC5_RS23370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS23385	COG1674	ftsk spoiiie
FORC5_RS23390	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS23390	COG1388	LysM domain
FORC5_RS23400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC5_RS23410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC5_RS23415	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC5_RS23420	COG1363	Peptidase, m42
FORC5_RS23430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS23445	COG0510	thiamine kinase activity
FORC5_RS23450	COG1523	belongs to the glycosyl hydrolase 13 family
FORC5_RS23460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC5_RS23465	COG1349	DNA-binding transcription factor activity
FORC5_RS23470	COG1187	pseudouridine synthase activity
FORC5_RS23475	COG2244	polysaccharide biosynthetic process
FORC5_RS23480	COG2081	HI0933 family
FORC5_RS23485	COG2814	Major facilitator Superfamily
FORC5_RS23495	COG3832	glyoxalase III activity
FORC5_RS23520	COG1329	Transcriptional regulator
FORC5_RS23545	COG0314	molybdopterin synthase activity
FORC5_RS23550	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC5_RS23555	COG0303	'Molybdopterin
FORC5_RS23565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC5_RS23570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC5_RS23590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC5_RS23600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC5_RS23640	COG2814	Major facilitator Superfamily
FORC5_RS23645	COG0475	glutathione-regulated potassium exporter activity
FORC5_RS23650	COG0490	domain, Protein
FORC5_RS23655	COG0582	viral genome integration into host DNA
FORC5_RS23665	COG1136	(ABC) transporter
FORC5_RS23685	COG1242	4 iron, 4 sulfur cluster binding
FORC5_RS23690	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FORC5_RS23695	COG1794	racemase activity, acting on amino acids and derivatives
FORC5_RS23710	COG2267	carboxylic ester hydrolase activity
FORC5_RS23715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC5_RS23720	COG0671	phosphoesterase, PA-phosphatase related
FORC5_RS23725	COG0438	transferase activity, transferring glycosyl groups
FORC5_RS23745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS23790	COG5002	protein histidine kinase activity
FORC5_RS23795	COG3852	Histidine kinase
FORC5_RS23800	COG0753	catalase activity
FORC5_RS23810	COG2267	carboxylic ester hydrolase activity
FORC5_RS23815	COG1368	sulfuric ester hydrolase activity
FORC5_RS23835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC5_RS23840	COG1116	anion transmembrane transporter activity
FORC5_RS23845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC5_RS23870	COG0494	nUDIX hydrolase
FORC5_RS23905	COG1854	S-ribosylhomocysteine lyase activity
FORC5_RS23915	COG0288	reversible hydration of carbon dioxide
FORC5_RS23920	COG1271	oxidase subunit
FORC5_RS23925	COG1294	oxidase, subunit
FORC5_RS23940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS23965	COG1842	Phage shock protein A
FORC5_RS23995	COG5002	protein histidine kinase activity
FORC5_RS24000	COG0745	RESPONSE REGULATOR receiver
FORC5_RS24025	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC5_RS24030	COG1597	lipid kinase activity
FORC5_RS24075	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS24085	COG0577	efflux transmembrane transporter activity
FORC5_RS24090	COG1136	(ABC) transporter
FORC5_RS24095	COG2207	Transcriptional regulator
FORC5_RS24095	COG3708	Transcriptional regulator
FORC5_RS24105	COG1131	(ABC) transporter
FORC5_RS24110	COG5658	integral membrane protein
FORC5_RS24115	COG0640	Transcriptional regulator
FORC5_RS24120	COG0745	RESPONSE REGULATOR receiver
FORC5_RS24125	COG2205	protein histidine kinase activity
FORC5_RS24130	COG0577	efflux transmembrane transporter activity
FORC5_RS24135	COG0577	efflux transmembrane transporter activity
FORC5_RS24140	COG1136	(ABC) transporter
FORC5_RS24145	COG0577	efflux transmembrane transporter activity
FORC5_RS24170	COG2188	Transcriptional regulator
FORC5_RS24190	COG3964	amidohydrolase
FORC5_RS24210	COG4948	Mandelate Racemase Muconate Lactonizing
FORC5_RS24225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC5_RS24230	COG0596	Alpha beta hydrolase
FORC5_RS24240	COG1169	isochorismate synthase
FORC5_RS24245	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC5_RS24250	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC5_RS24280	COG0058	SHG alpha-glucan phosphorylase activity
FORC5_RS24290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC5_RS24310	COG1404	Belongs to the peptidase S8 family
FORC5_RS24410	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC5_RS24445	COG1285	pathogenesis
FORC5_RS24450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC5_RS24470	COG2155	Conserved Protein
FORC5_RS24475	COG1098	S1 RNA binding domain
FORC5_RS24480	COG0436	Aminotransferase
FORC5_RS24485	COG1522	sequence-specific DNA binding
FORC5_RS24490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC5_RS24495	COG2267	carboxylic ester hydrolase activity
FORC5_RS24505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC5_RS24525	COG5018	Exonuclease
FORC5_RS24530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC5_RS24550	COG2050	protein possibly involved in aromatic compounds catabolism
FORC5_RS24560	COG1268	BioY protein
FORC5_RS24565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC5_RS24570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC5_RS24590	COG2076	Multidrug Resistance protein
FORC5_RS24595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC5_RS24605	COG3584	3D domain protein
FORC5_RS24620	COG1252	NADH dehydrogenase
FORC5_RS24635	COG3708	Transcriptional regulator
FORC5_RS24650	COG1683	Conserved Protein
FORC5_RS24670	COG0316	Belongs to the HesB IscA family
FORC5_RS24685	COG1252	NADH dehydrogenase
FORC5_RS24695	COG2274	protein secretion by the type I secretion system
FORC5_RS24700	COG0390	transport system, permease component
FORC5_RS24705	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC5_RS24750	COG4837	Protein of unknown function (DUF1462)
FORC5_RS24755	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC5_RS24765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC5_RS24770	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC5_RS24790	COG1358	cellular component organization or biogenesis
FORC5_RS24805	COG1136	(ABC) transporter
FORC5_RS24805	COG0577	efflux transmembrane transporter activity
FORC5_RS24810	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC5_RS24820	COG0647	UMP catabolic process
FORC5_RS24830	COG2445	Protein of unknown function DUF86
FORC5_RS24835	COG1494	fructose-1,6-bisphosphatase
FORC5_RS24860	COG4470	Protein conserved in bacteria
FORC5_RS24870	COG0789	Transcriptional regulator
FORC5_RS24875	COG4377	Putative membrane peptidase family (DUF2324)
FORC5_RS24900	COG0739	heme binding
FORC5_RS24910	COG3377	Domain of unknown function (DUF1805)
FORC5_RS24915	COG0737	Belongs to the 5'-nucleotidase family
FORC5_RS24920	COG0719	Fe-S assembly protein
FORC5_RS24925	COG0822	iron-sulfur transferase activity
FORC5_RS24930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC5_RS24935	COG0719	Fe-S assembly protein
FORC5_RS24940	COG0396	ATPase activity
FORC5_RS24945	COG1464	Belongs to the NlpA lipoprotein family
FORC5_RS24950	COG1464	Belongs to the NlpA lipoprotein family
FORC5_RS24955	COG2011	ABC-type metal ion transport system permease component
FORC5_RS24970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC5_RS24975	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FORC5_RS24985	COG1393	Belongs to the ArsC family
FORC5_RS25005	COG0039	L-malate dehydrogenase activity
FORC5_RS25025	COG1309	transcriptional regulator
FORC5_RS25030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC5_RS25035	COG1960	acyl-CoA dehydrogenase activity
FORC5_RS25040	COG0183	Belongs to the thiolase family
FORC5_RS25045	COG1024	Enoyl-CoA hydratase
FORC5_RS25045	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC5_RS25055	COG1686	Belongs to the peptidase S11 family
FORC5_RS25070	COG0011	TIGRFAM Protein of
FORC5_RS25075	COG0840	transmembrane signaling receptor activity
FORC5_RS25090	COG2814	Major facilitator Superfamily
FORC5_RS25095	COG0531	amino acid
FORC5_RS25120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC5_RS25155	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS25165	COG1376	ErfK ybiS ycfS ynhG family protein
FORC5_RS25170	COG0745	RESPONSE REGULATOR receiver
FORC5_RS25175	COG5002	protein histidine kinase activity
FORC5_RS25205	COG0840	transmembrane signaling receptor activity
FORC5_RS25210	COG2151	metal-sulfur cluster biosynthetic enzyme
FORC5_RS25215	COG3227	Zinc metalloprotease (Elastase)
FORC5_RS25235	COG0586	Pfam SNARE associated Golgi protein
FORC5_RS25240	COG0475	glutathione-regulated potassium exporter activity
FORC5_RS25245	COG0490	domain, Protein
FORC5_RS25255	COG1115	amino acid carrier protein
FORC5_RS25260	COG0783	Belongs to the Dps family
FORC5_RS25275	COG1611	Belongs to the LOG family
FORC5_RS25285	COG1528	Iron-storage protein
FORC5_RS25295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS25300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS25305	COG1115	amino acid carrier protein
FORC5_RS25310	COG1115	amino acid carrier protein
FORC5_RS25315	COG2910	NAD(P)H-binding
FORC5_RS25330	COG0656	L-ascorbic acid biosynthetic process
FORC5_RS25335	COG2814	Major facilitator Superfamily
FORC5_RS25340	COG1733	regulation of RNA biosynthetic process
FORC5_RS25350	COG1252	NADH dehydrogenase
FORC5_RS25405	COG0488	(ABC) transporter
FORC5_RS25410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC5_RS25480	COG0557	exoribonuclease II activity
FORC5_RS25485	COG1647	Serine aminopeptidase, S33
FORC5_RS25490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC5_RS25495	COG1346	cytolysis
FORC5_RS25530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC5_RS25545	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC5_RS25550	COG1668	transmembrane transport
FORC5_RS25555	COG4152	abc transporter atp-binding protein
FORC5_RS25560	COG4585	Histidine kinase
FORC5_RS25590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC5_RS25605	COG2323	membrane
FORC5_RS25620	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC5_RS25630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC5_RS25640	COG1051	belongs to the nudix hydrolase family
FORC5_RS25650	COG0492	ferredoxin-NADP+ reductase activity
FORC5_RS25655	COG0457	Tetratricopeptide repeat
FORC5_RS25660	COG0110	maltose O-acetyltransferase activity
FORC5_RS25680	COG1950	PFAM Membrane protein of
FORC5_RS25690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC5_RS25695	COG0556	nucleotide-excision repair
FORC5_RS25710	COG0789	Transcriptional regulator
FORC5_RS25735	COG0583	DNA-binding transcription factor activity
FORC5_RS25745	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC5_RS25750	COG0488	(ABC) transporter
FORC5_RS25760	COG1132	(ABC) transporter
FORC5_RS25765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC5_RS25770	COG0793	Belongs to the peptidase S41A family
FORC5_RS25770	COG3409	Peptidoglycan-binding domain 1 protein
FORC5_RS25775	COG2177	Part of the ABC transporter FtsEX involved in
FORC5_RS25780	COG2884	Cell division ATP-binding protein ftsE
FORC5_RS25795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC5_RS25805	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC5_RS25810	COG1278	Cold shock
FORC5_RS25815	COG1040	competence protein
FORC5_RS25820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FORC5_RS25825	COG1388	LysM domain
FORC5_RS25825	COG0791	NLP P60 protein
FORC5_RS25830	COG1733	regulation of RNA biosynthetic process
FORC5_RS25835	COG1307	EDD domain protein, DegV family
FORC5_RS25840	COG1739	Uncharacterized protein family UPF0029
FORC5_RS25845	COG1316	TRANSCRIPTIONal
FORC5_RS25850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC5_RS25855	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC5_RS25860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC5_RS25870	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC5_RS25870	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FORC5_RS25890	COG1486	melibiose metabolic process
FORC5_RS25895	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC5_RS25900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC5_RS25920	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC5_RS25930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC5_RS25935	COG1301	dicarboxylic acid transport
FORC5_RS25950	COG1511	domain protein
FORC5_RS25955	COG0583	DNA-binding transcription factor activity
FORC5_RS25960	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC5_RS25970	COG1271	oxidase subunit
FORC5_RS25975	COG1294	oxidase, subunit
FORC5_RS25980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC5_RS26000	COG1620	l-lactate permease
FORC5_RS26010	COG2389	metal-binding protein
FORC5_RS26020	COG1368	sulfuric ester hydrolase activity
FORC5_RS26030	COG1388	LysM domain
FORC5_RS26030	COG0791	NLP P60 protein
FORC5_RS26035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC5_RS26045	COG1215	transferase activity, transferring glycosyl groups
FORC5_RS26055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC5_RS26060	COG3584	3D domain protein
FORC5_RS26060	COG1388	LysM domain
FORC5_RS26085	COG4715	Zinc finger, swim domain protein
FORC5_RS26090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC5_RS26130	COG0577	efflux transmembrane transporter activity
FORC5_RS26135	COG1136	(ABC) transporter
FORC5_RS26160	COG5002	protein histidine kinase activity
FORC5_RS26165	COG0745	RESPONSE REGULATOR receiver
FORC5_RS26170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC5_RS26190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC5_RS26195	COG2244	polysaccharide biosynthetic process
FORC5_RS26215	COG0438	transferase activity, transferring glycosyl groups
FORC5_RS26220	COG0438	transferase activity, transferring glycosyl groups
FORC5_RS26235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC5_RS26240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC5_RS26245	COG1086	Polysaccharide biosynthesis protein
FORC5_RS26250	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC5_RS26255	COG4464	protein tyrosine phosphatase activity
FORC5_RS26260	COG0489	protein tyrosine kinase activity
FORC5_RS26265	COG3944	biosynthesis protein
FORC5_RS26270	COG0489	protein tyrosine kinase activity
FORC5_RS26285	COG1609	Transcriptional regulator
FORC5_RS26295	COG0739	heme binding
FORC5_RS26310	COG3279	Response regulator of the LytR AlgR family
FORC5_RS26315	COG2385	sporulation resulting in formation of a cellular spore
FORC5_RS26330	COG4836	Membrane
FORC5_RS26335	COG1007	ATP synthesis coupled electron transport
FORC5_RS26340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC5_RS26345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC5_RS26355	COG0839	Belongs to the complex I subunit 6 family
FORC5_RS26375	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC5_RS26390	COG5001	Diguanylate cyclase
FORC5_RS26390	COG3300	MHYT domain
FORC5_RS26440	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC5_RS26475	COG0698	ribose 5-phosphate isomerase
FORC5_RS26490	COG2259	Doxx family
FORC5_RS26495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC5_RS26510	COG0009	L-threonylcarbamoyladenylate synthase
FORC5_RS26545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC5_RS26550	COG1494	fructose-1,6-bisphosphatase
FORC5_RS26570	COG4821	SIS domain
FORC5_RS26580	COG3343	RNA polymerase activity
FORC5_RS26590	COG1960	acyl-CoA dehydrogenase activity
FORC5_RS26595	COG1960	acyl-CoA dehydrogenase activity
FORC5_RS26600	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC5_RS26605	COG0183	Belongs to the thiolase family
FORC5_RS26610	COG2181	nitrate reductase activity
FORC5_RS26610	COG0247	lactate metabolic process
FORC5_RS26615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC5_RS26625	COG5001	Diguanylate cyclase
FORC5_RS26625	COG3300	MHYT domain
FORC5_RS26640	COG3227	Zinc metalloprotease (Elastase)
FORC5_RS26645	COG2197	response regulator
FORC5_RS26650	COG4585	Histidine kinase
FORC5_RS26655	COG0842	Transport permease protein
FORC5_RS26660	COG1131	(ABC) transporter
FORC5_RS26665	COG0024	Methionine aminopeptidase
FORC5_RS26675	COG2234	aminopeptidase activity
FORC5_RS26685	COG1595	DNA-templated transcription, initiation
FORC5_RS26695	COG4506	Protein conserved in bacteria
FORC5_RS26700	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC5_RS26725	COG2814	Major facilitator Superfamily
FORC5_RS26730	COG0789	Transcriptional regulator
FORC5_RS26735	COG0584	glycerophosphoryl diester phosphodiesterase
FORC5_RS26740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC5_RS26750	COG1994	Peptidase M50
FORC5_RS26760	COG1078	dGTPase activity
FORC5_RS26765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC5_RS26770	COG1120	ATPase activity
FORC5_RS26775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS26780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC5_RS26800	COG0280	phosphate acetyltransferase
FORC5_RS26815	COG3773	Cell wall hydrolase
FORC5_RS26825	COG2363	Small membrane protein
FORC5_RS26835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC5_RS26840	COG2233	PERMEase
FORC5_RS26845	COG0561	phosphatase activity
FORC5_RS26850	COG2814	Major facilitator Superfamily
FORC5_RS26860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC5_RS26865	COG1131	(ABC) transporter
FORC5_RS26870	COG2755	lipolytic protein G-D-S-L family
FORC5_RS26875	COG1609	Transcriptional regulator
FORC5_RS26885	COG0460	homoserine dehydrogenase
FORC5_RS26895	COG2873	o-acetylhomoserine
FORC5_RS26905	COG1011	Hydrolase
FORC5_RS26910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC5_RS26920	COG2197	response regulator
FORC5_RS26925	COG4585	Histidine kinase
FORC5_RS26925	COG2203	Gaf domain
FORC5_RS26930	COG0351	phosphomethylpyrimidine kinase
FORC5_RS26935	COG3706	GGDEF domain
FORC5_RS26940	COG2879	small protein
FORC5_RS26945	COG1966	Carbon starvation protein
FORC5_RS26950	COG3279	Response regulator of the LytR AlgR family
FORC5_RS26955	COG0477	Major facilitator Superfamily
FORC5_RS26960	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC5_RS26965	COG0438	transferase activity, transferring glycosyl groups
FORC5_RS26980	COG0840	transmembrane signaling receptor activity
FORC5_RS26990	COG1607	acyl-coa hydrolase
FORC5_RS26995	COG1216	Glycosyl transferase, family 2
FORC5_RS27005	COG1216	Glycosyl transferase, family 2
FORC5_RS27015	COG4485	Bacterial membrane protein, YfhO
FORC5_RS27020	COG0463	Glycosyl transferase, family 2
FORC5_RS27025	COG0488	(ABC) transporter
FORC5_RS27030	COG1309	transcriptional regulator
FORC5_RS27035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC5_RS27040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC5_RS27040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC5_RS27045	COG0628	permease
FORC5_RS27065	COG3275	phosphorelay sensor kinase activity
FORC5_RS27070	COG2814	Major facilitator Superfamily
FORC5_RS27075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC5_RS27080	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FORC5_RS27100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC5_RS27105	COG1272	protein, Hemolysin III
FORC5_RS27125	COG1164	Oligoendopeptidase f
FORC5_RS27135	COG5002	protein histidine kinase activity
FORC5_RS27150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC5_RS27155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC5_RS27160	COG4853	Protein conserved in bacteria
FORC5_RS27170	COG5002	protein histidine kinase activity
FORC5_RS27175	COG0745	RESPONSE REGULATOR receiver
FORC5_RS27205	COG0305	Participates in initiation and elongation during chromosome replication
FORC5_RS27215	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FORC5_RS27240	COG0012	GTP binding
FORC5_RS27245	COG4481	Protein conserved in bacteria
FORC5_RS27250	COG0668	transmembrane transport
FORC5_RS27260	COG1475	DNA binding
FORC5_RS27265	COG1192	Involved in chromosome partitioning
FORC5_RS27290	COG1847	R3H domain protein
FORC5_RS27305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FORC5_RS27350	COG2814	Major facilitator Superfamily
FORC5_RS27435	COG0488	(ABC) transporter
FORC5_RS27490	COG3409	Peptidoglycan-binding domain 1 protein
FORC5_RS27490	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC5_RS27520	COG2376	Dihydroxyacetone kinase
FORC5_RS27880	COG0582	viral genome integration into host DNA
FORC5_RS27980	COG0277	FAD linked oxidase domain protein