locus-tag	class	description
FORC48_RS00010	COG0592	DNA-directed DNA polymerase activity
FORC48_RS00015	COG2501	S4 domain
FORC48_RS00025	COG0187	DNA topoisomerase II activity
FORC48_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC48_RS00065	COG0517	IMP dehydrogenase activity
FORC48_RS00065	COG0516	GMP reductase activity
FORC48_RS00070	COG1686	Belongs to the peptidase S11 family
FORC48_RS00100	COG1428	Deoxynucleoside kinase
FORC48_RS00105	COG1428	Deoxynucleoside kinase
FORC48_RS00110	COG1335	isochorismatase
FORC48_RS00120	COG0590	tRNA wobble adenosine to inosine editing
FORC48_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FORC48_RS00185	COG1982	Orn Lys Arg decarboxylase major
FORC48_RS00195	COG0470	DNA polymerase III
FORC48_RS00200	COG1774	PSP1 C-terminal conserved region
FORC48_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC48_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC48_RS00225	COG2002	toxin-antitoxin pair type II binding
FORC48_RS00235	COG0084	hydrolase, TatD family'
FORC48_RS00255	COG4466	Protein conserved in bacteria
FORC48_RS00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC48_RS00275	COG0251	oxidation-reduction process
FORC48_RS00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC48_RS00310	COG2002	toxin-antitoxin pair type II binding
FORC48_RS00315	COG2244	polysaccharide biosynthetic process
FORC48_RS00320	COG3956	TIGRFAM MazG family protein
FORC48_RS00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC48_RS00345	COG1098	S1 RNA binding domain
FORC48_RS00360	COG2208	phosphoserine phosphatase activity
FORC48_RS00370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC48_RS00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC48_RS00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC48_RS00400	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC48_RS00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC48_RS00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC48_RS00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC48_RS00425	COG1396	sequence-specific DNA binding
FORC48_RS00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC48_RS00520	COG3880	PFAM UvrB UvrC protein
FORC48_RS00530	COG0542	response to heat
FORC48_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC48_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
FORC48_RS00565	COG1045	serine acetyltransferase
FORC48_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC48_RS00585	COG3688	RNA-binding protein containing a PIN domain
FORC48_RS00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC48_RS00605	COG0250	Participates in transcription elongation, termination and antitermination
FORC48_RS00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC48_RS00630	COG2813	Specifically methylates the guanine in position
FORC48_RS00645	COG1358	cellular component organization or biogenesis
FORC48_RS00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FORC48_RS00720	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC48_RS00780	COG0201	protein transport
FORC48_RS00790	COG0024	Methionine aminopeptidase
FORC48_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FORC48_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FORC48_RS00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS00865	COG0489	protein tyrosine kinase activity
FORC48_RS00875	COG2194	sulfuric ester hydrolase activity
FORC48_RS00880	COG0726	polysaccharide deacetylase
FORC48_RS00960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FORC48_RS00965	COG4856	YbbR-like protein
FORC48_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS01020	COG2011	ABC-type metal ion transport system permease component
FORC48_RS01025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC48_RS01030	COG1464	Belongs to the NlpA lipoprotein family
FORC48_RS01035	COG0604	alcohol dehydrogenase
FORC48_RS01045	COG0277	FAD linked oxidase domain protein
FORC48_RS01050	COG2271	Major facilitator Superfamily
FORC48_RS01060	COG2814	Major facilitator Superfamily
FORC48_RS01075	COG0601	transmembrane transport
FORC48_RS01080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_RS01085	COG0444	Belongs to the ABC transporter superfamily
FORC48_RS01090	COG4608	Belongs to the ABC transporter superfamily
FORC48_RS01095	COG4166	transmembrane transport
FORC48_RS01105	COG2207	Transcriptional regulator
FORC48_RS01120	COG4166	transmembrane transport
FORC48_RS01125	COG4166	transmembrane transport
FORC48_RS01130	COG0656	L-ascorbic acid biosynthetic process
FORC48_RS01150	COG4149	molybdate abc transporter
FORC48_RS01155	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC48_RS01160	COG1910	domain protein
FORC48_RS01180	COG0697	spore germination
FORC48_RS01200	COG0204	Acyl-transferase
FORC48_RS01215	COG1609	Transcriptional regulator
FORC48_RS01225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS01245	COG5298	Protein conserved in bacteria
FORC48_RS01270	COG0488	(ABC) transporter
FORC48_RS01285	COG0747	negative chemotaxis
FORC48_RS01290	COG0601	transmembrane transport
FORC48_RS01295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_RS01300	COG0444	Belongs to the ABC transporter superfamily
FORC48_RS01305	COG4608	Belongs to the ABC transporter superfamily
FORC48_RS01310	COG0561	phosphatase activity
FORC48_RS01340	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FORC48_RS01345	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC48_RS01360	COG0531	amino acid
FORC48_RS01365	COG2814	Major facilitator Superfamily
FORC48_RS01375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC48_RS01385	COG4294	response to UV
FORC48_RS01390	COG0705	Rhomboid family
FORC48_RS01400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC48_RS01405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC48_RS01410	COG0864	Transcriptional regulator
FORC48_RS01415	COG2337	Toxic component of a toxin-antitoxin (TA) module
FORC48_RS01420	COG2183	response to ionizing radiation
FORC48_RS01520	COG0802	atpase or kinase
FORC48_RS01525	COG1214	PFAM Peptidase M22, glycoprotease
FORC48_RS01530	COG0456	acetyltransferase
FORC48_RS01540	COG0488	(ABC) transporter
FORC48_RS01555	COG1266	CAAX protease self-immunity
FORC48_RS01575	COG2252	PERMEase
FORC48_RS01585	COG5002	protein histidine kinase activity
FORC48_RS01610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC48_RS01655	COG2205	protein histidine kinase activity
FORC48_RS01660	COG0745	RESPONSE REGULATOR receiver
FORC48_RS01700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_RS01710	COG0463	Glycosyl transferase, family 2
FORC48_RS01710	COG1216	Glycosyl transferase, family 2
FORC48_RS01730	COG0697	spore germination
FORC48_RS01760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC48_RS01765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC48_RS01770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC48_RS01780	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC48_RS01795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC48_RS01805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC48_RS01815	COG0151	Belongs to the GarS family
FORC48_RS01845	COG0210	DNA helicase
FORC48_RS01855	COG4851	CamS sex pheromone cAM373 precursor
FORC48_RS01870	COG1335	isochorismatase
FORC48_RS01880	COG2011	ABC-type metal ion transport system permease component
FORC48_RS01885	COG1464	Belongs to the NlpA lipoprotein family
FORC48_RS01900	COG0003	Pfam Anion-transporting ATPase
FORC48_RS01905	COG1846	Transcriptional regulator
FORC48_RS01910	COG4682	membrane
FORC48_RS01930	COG1597	lipid kinase activity
FORC48_RS01940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC48_RS01950	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS01955	COG2076	Multidrug Resistance protein
FORC48_RS01965	COG2309	aminopeptidase activity
FORC48_RS01980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS01990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC48_RS01995	COG4807	Protein conserved in bacteria
FORC48_RS02020	COG1757	Na H antiporter
FORC48_RS02025	COG1473	amidohydrolase
FORC48_RS02040	COG0450	alkyl hydroperoxide reductase
FORC48_RS02060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS02065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS02070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS02080	COG0492	ferredoxin-NADP+ reductase activity
FORC48_RS02095	COG0166	Belongs to the GPI family
FORC48_RS02120	COG5002	protein histidine kinase activity
FORC48_RS02140	COG3541	Predicted nucleotidyltransferase
FORC48_RS02145	COG2814	Major facilitator Superfamily
FORC48_RS02150	COG0723	plastoquinol--plastocyanin reductase activity
FORC48_RS02150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_RS02160	COG0765	amino acid transport
FORC48_RS02165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_RS02180	COG0840	transmembrane signaling receptor activity
FORC48_RS02205	COG0549	Belongs to the carbamate kinase family
FORC48_RS02210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_RS02220	COG0277	FAD linked oxidase domain protein
FORC48_RS02225	COG0366	Alpha amylase catalytic
FORC48_RS02230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_RS02230	COG2190	(PTS) system
FORC48_RS02230	COG1263	PTS System
FORC48_RS02260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC48_RS02280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_RS02285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_RS02290	COG1116	anion transmembrane transporter activity
FORC48_RS02295	COG0488	(ABC) transporter
FORC48_RS02345	COG2270	Major facilitator Superfamily
FORC48_RS02375	COG2310	stress, protein
FORC48_RS02380	COG2310	stress, protein
FORC48_RS02385	COG2310	stress, protein
FORC48_RS02390	COG0861	Integral membrane protein TerC family
FORC48_RS02400	COG3853	Toxic anion resistance protein (TelA)
FORC48_RS02415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC48_RS02425	COG1295	ribonuclease BN
FORC48_RS02435	COG2217	Heavy metal translocating P-type atpase
FORC48_RS02440	COG0697	spore germination
FORC48_RS02450	COG0681	Belongs to the peptidase S26 family
FORC48_RS02460	COG0586	Pfam SNARE associated Golgi protein
FORC48_RS02475	COG3871	stress protein (general stress protein 26)
FORC48_RS02480	COG0387	Pfam Sodium calcium exchanger
FORC48_RS02490	COG0535	radical SAM domain protein
FORC48_RS02510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC48_RS02515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC48_RS02530	COG3829	transcription factor binding
FORC48_RS02540	COG0833	amino acid
FORC48_RS02545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC48_RS02580	COG1263	PTS System
FORC48_RS02580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_RS02585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_RS02600	COG0463	Glycosyl transferase, family 2
FORC48_RS02610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC48_RS02610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_RS02630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC48_RS02650	COG1228	amidohydrolase
FORC48_RS02655	COG1090	epimerase
FORC48_RS02685	COG1988	membrane-bound metal-dependent
FORC48_RS02690	COG1194	a g-specific adenine glycosylase
FORC48_RS02715	COG1132	(ABC) transporter
FORC48_RS02720	COG4129	membrane
FORC48_RS02725	COG0070	glutamate synthase
FORC48_RS02725	COG0067	glutamate synthase
FORC48_RS02725	COG0069	glutamate synthase activity
FORC48_RS02735	COG4555	ABC transporter
FORC48_RS02755	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC48_RS02760	COG0735	belongs to the Fur family
FORC48_RS02885	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC48_RS02910	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC48_RS02925	COG2766	serine protein kinase
FORC48_RS02950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC48_RS02960	COG1585	Membrane protein implicated in regulation of membrane protease activity
FORC48_RS02965	COG2268	Band 7 protein
FORC48_RS02975	COG3290	protein histidine kinase activity
FORC48_RS02980	COG4565	transcriptional regulatory protein
FORC48_RS02985	COG2851	Citrate transporter
FORC48_RS03010	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC48_RS03015	COG3842	ATPase activity
FORC48_RS03020	COG1175	transmembrane transport
FORC48_RS03025	COG0395	ABC-type sugar transport system, permease component
FORC48_RS03035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC48_RS03040	COG0745	RESPONSE REGULATOR receiver
FORC48_RS03045	COG5002	protein histidine kinase activity
FORC48_RS03045	COG3850	Histidine kinase
FORC48_RS03055	COG4990	cell redox homeostasis
FORC48_RS03065	COG3290	protein histidine kinase activity
FORC48_RS03070	COG4565	transcriptional regulatory protein
FORC48_RS03075	COG3493	citrate carrier protein
FORC48_RS03080	COG0281	malic enzyme
FORC48_RS03090	COG0697	spore germination
FORC48_RS03095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS03105	COG5002	protein histidine kinase activity
FORC48_RS03120	COG0454	-acetyltransferase
FORC48_RS03120	COG0456	acetyltransferase
FORC48_RS03125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC48_RS03130	COG3383	formate dehydrogenase (NAD+) activity
FORC48_RS03135	COG2427	Protein of unknown function (DUF1641)
FORC48_RS03150	COG0531	amino acid
FORC48_RS03160	COG0640	Transcriptional regulator
FORC48_RS03165	COG2217	Heavy metal translocating P-type atpase
FORC48_RS03170	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC48_RS03180	COG3227	Zinc metalloprotease (Elastase)
FORC48_RS03200	COG2720	vancomycin resistance protein
FORC48_RS03205	COG1316	TRANSCRIPTIONal
FORC48_RS03210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS03215	COG0346	lactoylglutathione lyase activity
FORC48_RS03220	COG1253	flavin adenine dinucleotide binding
FORC48_RS03225	COG1027	Aspartate ammonia-lyase
FORC48_RS03230	COG1620	l-lactate permease
FORC48_RS03245	COG3104	oligopeptide transport
FORC48_RS03250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS03255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS03270	COG2226	methyltransferase
FORC48_RS03280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_RS03290	COG4548	von Willebrand factor, type A
FORC48_RS03295	COG0714	Associated with various cellular activities
FORC48_RS03320	COG0531	amino acid
FORC48_RS03325	COG2188	Transcriptional regulator
FORC48_RS03330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_RS03330	COG1263	PTS System
FORC48_RS03335	COG0366	Alpha amylase catalytic
FORC48_RS03350	COG0697	spore germination
FORC48_RS03355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC48_RS03370	COG1126	abc transporter atp-binding protein
FORC48_RS03375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_RS03380	COG0765	amino acid transport
FORC48_RS03385	COG0765	amino acid transport
FORC48_RS03390	COG0833	amino acid
FORC48_RS03415	COG2378	regulation of single-species biofilm formation
FORC48_RS03420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC48_RS03425	COG5002	protein histidine kinase activity
FORC48_RS03450	COG0659	secondary active sulfate transmembrane transporter activity
FORC48_RS03465	COG2271	Major facilitator Superfamily
FORC48_RS03470	COG1846	Transcriptional regulator
FORC48_RS03475	COG0477	Major facilitator Superfamily
FORC48_RS03480	COG1609	Transcriptional regulator
FORC48_RS03485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC48_RS03500	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC48_RS03505	COG1879	ABC-type sugar transport system periplasmic component
FORC48_RS03535	COG1063	alcohol dehydrogenase
FORC48_RS03585	COG0840	transmembrane signaling receptor activity
FORC48_RS03590	COG1388	LysM domain
FORC48_RS03590	COG3584	3D domain protein
FORC48_RS03595	COG1476	TRANSCRIPTIONal
FORC48_RS03615	COG3104	oligopeptide transport
FORC48_RS03620	COG1114	Component of the transport system for branched-chain amino acids
FORC48_RS03635	COG1113	amino acid transport
FORC48_RS03640	COG2252	PERMEase
FORC48_RS03665	COG2153	protein acetylation
FORC48_RS03675	COG0569	domain protein
FORC48_RS03675	COG0475	glutathione-regulated potassium exporter activity
FORC48_RS03685	COG1845	cytochrome c oxidase, subunit III
FORC48_RS03690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC48_RS03700	COG0833	amino acid
FORC48_RS03705	COG4990	cell redox homeostasis
FORC48_RS03720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_RS03725	COG0697	spore germination
FORC48_RS03730	COG0531	amino acid
FORC48_RS03745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC48_RS03750	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC48_RS03755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FORC48_RS03755	COG1918	ferrous iron import across plasma membrane
FORC48_RS03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC48_RS03765	COG0573	inorganic phosphate transmembrane transporter activity
FORC48_RS03770	COG0581	inorganic phosphate transmembrane transporter activity
FORC48_RS03775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC48_RS03895	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FORC48_RS03920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC48_RS03925	COG1116	anion transmembrane transporter activity
FORC48_RS03930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_RS03935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_RS03940	COG0352	thiamine-phosphate diphosphorylase activity
FORC48_RS03945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_RS03950	COG2104	thiamine diphosphate biosynthetic process
FORC48_RS03960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_RS03965	COG0351	phosphomethylpyrimidine kinase
FORC48_RS04010	COG2205	protein histidine kinase activity
FORC48_RS04015	COG2814	Major facilitator Superfamily
FORC48_RS04020	COG1846	Transcriptional regulator
FORC48_RS04030	COG2252	PERMEase
FORC48_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS04050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC48_RS04055	COG1621	beta-fructofuranosidase activity
FORC48_RS04060	COG1263	PTS System
FORC48_RS04060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_RS04065	COG1609	Transcriptional regulator
FORC48_RS04115	COG0778	Nitroreductase
FORC48_RS04120	COG2719	SpoVR family
FORC48_RS04130	COG3591	Belongs to the peptidase S1B family
FORC48_RS04160	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC48_RS04165	COG1937	Protein conserved in bacteria
FORC48_RS04170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS04170	COG0425	Belongs to the sulfur carrier protein TusA family
FORC48_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS04175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS04180	COG0425	Belongs to the sulfur carrier protein TusA family
FORC48_RS04185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS04185	COG0425	Belongs to the sulfur carrier protein TusA family
FORC48_RS04190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS04195	COG2210	Belongs to the sulfur carrier protein TusA family
FORC48_RS04200	COG0730	response to heat
FORC48_RS04210	COG1316	TRANSCRIPTIONal
FORC48_RS04215	COG0604	alcohol dehydrogenase
FORC48_RS04220	COG1283	sodium-dependent phosphate transmembrane transporter activity
FORC48_RS04235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC48_RS04235	COG3711	transcriptional antiterminator
FORC48_RS04240	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC48_RS04245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC48_RS04270	COG3584	3D domain protein
FORC48_RS04270	COG1388	LysM domain
FORC48_RS04275	COG0577	efflux transmembrane transporter activity
FORC48_RS04280	COG1136	(ABC) transporter
FORC48_RS04290	COG5522	Integral membrane protein (intg_mem_TP0381)
FORC48_RS04305	COG1114	Component of the transport system for branched-chain amino acids
FORC48_RS04310	COG3546	catalase activity
FORC48_RS04345	COG0586	Pfam SNARE associated Golgi protein
FORC48_RS04380	COG0531	amino acid
FORC48_RS04385	COG0475	glutathione-regulated potassium exporter activity
FORC48_RS04395	COG1737	Transcriptional regulator
FORC48_RS04405	COG1263	PTS System
FORC48_RS04405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_RS04415	COG2259	Doxx family
FORC48_RS04435	COG1522	sequence-specific DNA binding
FORC48_RS04445	COG0300	oxidoreductase activity
FORC48_RS04465	COG1309	transcriptional regulator
FORC48_RS04470	COG2814	Major facilitator Superfamily
FORC48_RS04475	COG1733	regulation of RNA biosynthetic process
FORC48_RS04490	COG4533	DNA binding
FORC48_RS04495	COG2211	Major facilitator Superfamily
FORC48_RS04505	COG0693	protein deglycase activity
FORC48_RS04510	COG0753	catalase activity
FORC48_RS04510	COG0693	protein deglycase activity
FORC48_RS04520	COG0531	amino acid
FORC48_RS04525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC48_RS04535	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS04555	COG1132	(ABC) transporter
FORC48_RS04560	COG1132	(ABC) transporter
FORC48_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_RS04575	COG0765	amino acid transport
FORC48_RS04580	COG1126	abc transporter atp-binding protein
FORC48_RS04595	COG0189	ligase activity
FORC48_RS04630	COG0028	Belongs to the TPP enzyme family
FORC48_RS04635	COG3527	Alpha-acetolactate decarboxylase
FORC48_RS04645	COG0561	phosphatase activity
FORC48_RS04655	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_RS04655	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS04660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC48_RS04670	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_RS04685	COG0659	secondary active sulfate transmembrane transporter activity
FORC48_RS04690	COG2244	polysaccharide biosynthetic process
FORC48_RS04710	COG1024	Enoyl-CoA hydratase
FORC48_RS04730	COG1363	Peptidase, m42
FORC48_RS04765	COG0601	transmembrane transport
FORC48_RS04770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_RS04775	COG0444	Belongs to the ABC transporter superfamily
FORC48_RS04780	COG4608	Belongs to the ABC transporter superfamily
FORC48_RS04805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS04820	COG1136	(ABC) transporter
FORC48_RS04820	COG0577	efflux transmembrane transporter activity
FORC48_RS04885	COG0477	Major facilitator Superfamily
FORC48_RS04890	COG3290	protein histidine kinase activity
FORC48_RS04895	COG4565	transcriptional regulatory protein
FORC48_RS04900	COG3181	Tripartite tricarboxylate transporter family receptor
FORC48_RS04945	COG1475	DNA binding
FORC48_RS04955	COG0305	Participates in initiation and elongation during chromosome replication
FORC48_RS04990	COG0477	Major facilitator Superfamily
FORC48_RS05005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS05035	COG1073	alpha beta
FORC48_RS05085	COG1183	phosphatidylcholine synthase activity
FORC48_RS05100	COG2376	Dihydroxyacetone kinase
FORC48_RS05110	COG2376	Dihydroxyacetone kinase
FORC48_RS05150	COG1388	LysM domain
FORC48_RS05150	COG3584	3D domain protein
FORC48_RS05155	COG1388	LysM domain
FORC48_RS05155	COG0791	NLP P60 protein
FORC48_RS05160	COG2373	Large extracellular alpha-helical protein
FORC48_RS05180	COG0596	Alpha beta hydrolase
FORC48_RS05250	COG1191	sigma factor activity
FORC48_RS05260	COG2208	phosphoserine phosphatase activity
FORC48_RS05265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC48_RS05270	COG2205	protein histidine kinase activity
FORC48_RS05270	COG0784	Response regulator, receiver
FORC48_RS05270	COG5002	protein histidine kinase activity
FORC48_RS05315	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FORC48_RS05335	COG0420	3'-5' exonuclease activity
FORC48_RS05340	COG4717	serine-type aminopeptidase activity
FORC48_RS05350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_RS05370	COG0346	lactoylglutathione lyase activity
FORC48_RS05375	COG0346	lactoylglutathione lyase activity
FORC48_RS05380	COG0457	Tetratricopeptide repeat
FORC48_RS05390	COG2267	carboxylic ester hydrolase activity
FORC48_RS05410	COG2140	Oxalate decarboxylase
FORC48_RS05415	COG3620	sequence-specific DNA binding
FORC48_RS05420	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FORC48_RS05425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC48_RS05435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC48_RS05440	COG1695	Transcriptional regulator
FORC48_RS05455	COG1595	DNA-templated transcription, initiation
FORC48_RS05480	COG3973	AAA domain
FORC48_RS05515	COG4980	gas vesicle protein
FORC48_RS05520	COG0537	adenosine 5'-monophosphoramidase activity
FORC48_RS05530	COG1131	(ABC) transporter
FORC48_RS05535	COG4473	ABC transporter
FORC48_RS05560	COG3402	PFAM membrane-flanked domain
FORC48_RS05565	COG3428	Bacterial PH domain
FORC48_RS05610	COG0697	spore germination
FORC48_RS05615	COG3402	PFAM membrane-flanked domain
FORC48_RS05620	COG3428	Bacterial PH domain
FORC48_RS05625	COG2329	Antibiotic biosynthesis monooxygenase
FORC48_RS05630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_RS05645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FORC48_RS05680	COG1309	transcriptional regulator
FORC48_RS05685	COG1511	domain protein
FORC48_RS05685	COG1511	domain protein
FORC48_RS05695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS05700	COG1609	Transcriptional regulator
FORC48_RS05710	COG1234	tRNA 3'-trailer cleavage
FORC48_RS05715	COG0095	Lipoate-protein ligase
FORC48_RS05725	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_RS05735	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FORC48_RS05745	COG4208	sulfate ABC transporter
FORC48_RS05760	COG3209	COG3209 Rhs family protein
FORC48_RS05865	COG1073	alpha beta
FORC48_RS05870	COG1408	metallophosphoesterase
FORC48_RS05875	COG1078	dGTPase activity
FORC48_RS05885	COG1595	DNA-templated transcription, initiation
FORC48_RS05890	COG2207	Transcriptional regulator
FORC48_RS05890	COG3708	Transcriptional regulator
FORC48_RS05905	COG2205	protein histidine kinase activity
FORC48_RS05910	COG0745	RESPONSE REGULATOR receiver
FORC48_RS05930	COG0501	Belongs to the peptidase M48B family
FORC48_RS05935	COG0840	transmembrane signaling receptor activity
FORC48_RS05940	COG3693	PFAM glycoside hydrolase, family 10
FORC48_RS05950	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC48_RS05955	COG2224	Isocitrate lyase
FORC48_RS05970	COG1278	Cold shock
FORC48_RS05990	COG0398	Pfam SNARE associated Golgi protein
FORC48_RS06050	COG0179	Fumarylacetoacetate (FAA) hydrolase
FORC48_RS06075	COG0367	asparagine synthase
FORC48_RS06085	COG0753	catalase activity
FORC48_RS06090	COG0004	ammonium transporteR
FORC48_RS06115	COG2996	Protein conserved in bacteria
FORC48_RS06130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS06145	COG0561	phosphatase activity
FORC48_RS06170	COG2267	carboxylic ester hydrolase activity
FORC48_RS06190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC48_RS06195	COG5504	Zn-dependent protease
FORC48_RS06215	COG0180	Tryptophanyl-tRNA synthetase
FORC48_RS06230	COG4166	transmembrane transport
FORC48_RS06235	COG0601	transmembrane transport
FORC48_RS06240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC48_RS06245	COG0444	Belongs to the ABC transporter superfamily
FORC48_RS06250	COG4608	Belongs to the ABC transporter superfamily
FORC48_RS06255	COG0534	Mate efflux family protein
FORC48_RS06260	COG4166	transmembrane transport
FORC48_RS06280	COG0861	Integral membrane protein TerC family
FORC48_RS06300	COG1164	Oligoendopeptidase f
FORC48_RS06315	COG2346	COG2346, Truncated hemoglobins
FORC48_RS06320	COG4116	CYTH
FORC48_RS06330	COG2357	RelA SpoT domain protein
FORC48_RS06340	COG0564	pseudouridine synthase activity
FORC48_RS06355	COG0772	Belongs to the SEDS family
FORC48_RS06360	COG1216	Glycosyl transferase, family 2
FORC48_RS06380	COG0457	Tetratricopeptide repeat
FORC48_RS06380	COG0463	Glycosyl transferase, family 2
FORC48_RS06400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FORC48_RS06415	COG1091	dTDP-4-dehydrorhamnose reductase activity
FORC48_RS06460	COG2153	protein acetylation
FORC48_RS06470	COG2382	esterase
FORC48_RS06495	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_RS06510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC48_RS06510	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC48_RS06545	COG1620	l-lactate permease
FORC48_RS06550	COG5634	Uncharacterized conserved protein (DUF2278)
FORC48_RS06605	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC48_RS06615	COG1476	TRANSCRIPTIONal
FORC48_RS06675	COG1686	Belongs to the peptidase S11 family
FORC48_RS06680	COG0681	Belongs to the peptidase S26 family
FORC48_RS06715	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS06725	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC48_RS06730	COG1177	transmembrane transport
FORC48_RS06745	COG2409	Drug exporters of the RND superfamily
FORC48_RS06755	COG0564	pseudouridine synthase activity
FORC48_RS06765	COG2340	Cysteine-rich secretory protein family
FORC48_RS06770	COG0247	lactate metabolic process
FORC48_RS06775	COG0277	FAD linked oxidase domain protein
FORC48_RS06780	COG3835	regulator
FORC48_RS06790	COG0745	RESPONSE REGULATOR receiver
FORC48_RS06795	COG5002	protein histidine kinase activity
FORC48_RS06800	COG2186	Transcriptional regulator
FORC48_RS06820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FORC48_RS06830	COG2116	formate transmembrane transporter activity
FORC48_RS06835	COG0861	Integral membrane protein TerC family
FORC48_RS06840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC48_RS06850	COG2030	dehydratase
FORC48_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS06875	COG3243	poly(R)-hydroxyalkanoic acid synthase
FORC48_RS06885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC48_RS06905	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC48_RS06910	COG3842	ATPase activity
FORC48_RS06935	COG1349	DNA-binding transcription factor activity
FORC48_RS06950	COG0235	Class ii aldolase
FORC48_RS06960	COG2861	carbohydrate metabolic process
FORC48_RS06970	COG3852	Histidine kinase
FORC48_RS06975	COG1846	Transcriptional regulator
FORC48_RS06985	COG2318	DinB family
FORC48_RS06995	COG5002	protein histidine kinase activity
FORC48_RS07005	COG0720	synthase
FORC48_RS07020	COG4873	Protein conserved in bacteria
FORC48_RS07060	COG1780	Probably involved in ribonucleotide reductase function
FORC48_RS07065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC48_RS07070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC48_RS07075	COG1725	Transcriptional regulator
FORC48_RS07080	COG1131	(ABC) transporter
FORC48_RS07090	COG1131	(ABC) transporter
FORC48_RS07095	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC48_RS07100	COG1266	CAAX protease self-immunity
FORC48_RS07110	COG1522	sequence-specific DNA binding
FORC48_RS07120	COG1335	isochorismatase
FORC48_RS07130	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC48_RS07135	COG2070	2-Nitropropane dioxygenase
FORC48_RS07140	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC48_RS07150	COG1696	Membrane protein involved in D-alanine export
FORC48_RS07175	COG0716	FMN binding
FORC48_RS07235	COG1846	Transcriptional regulator
FORC48_RS07245	COG1301	dicarboxylic acid transport
FORC48_RS07250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC48_RS07255	COG4709	membrane
FORC48_RS07260	COG3874	Sporulation protein YtfJ
FORC48_RS07290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_RS07295	COG0028	Belongs to the TPP enzyme family
FORC48_RS07300	COG0440	acetolactate synthase activity
FORC48_RS07375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC48_RS07390	COG1183	phosphatidylcholine synthase activity
FORC48_RS07395	COG1368	sulfuric ester hydrolase activity
FORC48_RS07405	COG0019	diaminopimelate decarboxylase activity
FORC48_RS07425	COG0529	Catalyzes the synthesis of activated sulfate
FORC48_RS07430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC48_RS07450	COG1648	precorrin-2 dehydrogenase activity
FORC48_RS07460	COG0733	neurotransmitter:sodium symporter activity
FORC48_RS07480	COG1757	Na H antiporter
FORC48_RS07495	COG4758	membrane
FORC48_RS07500	COG4585	Histidine kinase
FORC48_RS07505	COG2197	response regulator
FORC48_RS07515	COG1114	Component of the transport system for branched-chain amino acids
FORC48_RS07570	COG0730	response to heat
FORC48_RS07575	COG0306	phosphate transporter
FORC48_RS07580	COG1392	Phosphate transport regulator
FORC48_RS07585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_RS07600	COG3852	Histidine kinase
FORC48_RS07605	COG1801	Protein of unknown function DUF72
FORC48_RS07615	COG0582	viral genome integration into host DNA
FORC48_RS07620	COG5002	protein histidine kinase activity
FORC48_RS07635	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FORC48_RS07635	COG0392	lysyltransferase activity
FORC48_RS07650	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC48_RS07655	COG1686	Belongs to the peptidase S11 family
FORC48_RS07660	COG2715	membrane protein required for spore maturation
FORC48_RS07665	COG0700	Nucleoside recognition
FORC48_RS07670	COG1187	pseudouridine synthase activity
FORC48_RS07680	COG1333	cytochrome c biogenesis protein
FORC48_RS07685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC48_RS07690	COG0745	RESPONSE REGULATOR receiver
FORC48_RS07695	COG5002	protein histidine kinase activity
FORC48_RS07700	COG2096	Adenosyltransferase
FORC48_RS07715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FORC48_RS07720	COG1141	Ferredoxin
FORC48_RS07730	COG0514	ATP-dependent DNA helicase (RecQ)
FORC48_RS07735	COG1266	CAAX protease self-immunity
FORC48_RS07745	COG1408	metallophosphoesterase
FORC48_RS07750	COG0789	Transcriptional regulator
FORC48_RS07760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FORC48_RS07780	COG0492	ferredoxin-NADP+ reductase activity
FORC48_RS07785	COG0252	asparaginase activity
FORC48_RS07855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC48_RS07870	COG0142	geranyltranstransferase activity
FORC48_RS07880	COG0142	geranyltranstransferase activity
FORC48_RS07905	COG0457	Tetratricopeptide repeat
FORC48_RS07925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC48_RS07930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC48_RS07930	COG2010	Cytochrome c
FORC48_RS07935	COG4347	Protein of unknown function (DUF1405)
FORC48_RS07950	COG2738	Putative neutral zinc metallopeptidase
FORC48_RS07960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS07965	COG1694	Mazg nucleotide pyrophosphohydrolase
FORC48_RS07985	COG0438	transferase activity, transferring glycosyl groups
FORC48_RS08025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC48_RS08025	COG1199	ATP-dependent helicase activity
FORC48_RS08045	COG3935	DnaD domain protein
FORC48_RS08050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC48_RS08060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_RS08060	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC48_RS08120	COG0116	Belongs to the methyltransferase superfamily
FORC48_RS08140	COG0457	Tetratricopeptide repeat
FORC48_RS08160	COG1199	ATP-dependent helicase activity
FORC48_RS08165	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC48_RS08175	COG0024	Methionine aminopeptidase
FORC48_RS08185	COG2233	PERMEase
FORC48_RS08190	COG2311	Membrane
FORC48_RS08200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC48_RS08210	COG0456	acetyltransferase
FORC48_RS08245	COG0754	glutathionylspermidine amidase activity
FORC48_RS08260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC48_RS08275	COG3944	biosynthesis protein
FORC48_RS08285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC48_RS08300	COG1215	transferase activity, transferring glycosyl groups
FORC48_RS08305	COG0438	transferase activity, transferring glycosyl groups
FORC48_RS08320	COG0454	-acetyltransferase
FORC48_RS08340	COG0328	RNA-DNA hybrid ribonuclease activity
FORC48_RS08375	COG3403	YqcI/YcgG family
FORC48_RS08380	COG1280	lysine exporter protein (LysE YggA)
FORC48_RS08400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_RS08405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC48_RS08415	COG0475	glutathione-regulated potassium exporter activity
FORC48_RS08420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC48_RS08425	COG0789	Transcriptional regulator
FORC48_RS08425	COG4978	Transcriptional regulator
FORC48_RS08435	COG2323	membrane
FORC48_RS08440	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC48_RS08475	COG1923	regulation of RNA biosynthetic process
FORC48_RS08485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC48_RS08490	COG1360	Flagellar Motor Protein
FORC48_RS08495	COG2201	protein-glutamate methylesterase activity
FORC48_RS08500	COG2198	Histidine kinase
FORC48_RS08500	COG0643	Histidine kinase
FORC48_RS08505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_RS08505	COG1776	CheC inhibitor of MCP methylation
FORC48_RS08520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC48_RS08540	COG1256	bacterial-type flagellum assembly
FORC48_RS08545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC48_RS08565	COG1815	bacterial-type flagellum-dependent cell motility
FORC48_RS08570	COG1558	bacterial-type flagellum-dependent cell motility
FORC48_RS08580	COG1766	The M ring may be actively involved in energy transduction
FORC48_RS08585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_RS08595	COG1157	protein secretion by the type III secretion system
FORC48_RS08615	COG1749	Flagellar hook protein flgE
FORC48_RS08630	COG0784	Response regulator, receiver
FORC48_RS08630	COG0835	chemotaxis
FORC48_RS08640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC48_RS08645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC48_RS08650	COG0741	lytic transglycosylase activity
FORC48_RS08660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_RS08665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC48_RS08665	COG1776	CheC inhibitor of MCP methylation
FORC48_RS08675	COG1338	Plays a role in the flagellum-specific transport system
FORC48_RS08680	COG1987	bacterial-type flagellum assembly
FORC48_RS08690	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC48_RS08695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC48_RS08700	COG1419	protein localization to endoplasmic reticulum
FORC48_RS08705	COG4786	Flagellar basal body rod
FORC48_RS08710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC48_RS08745	COG2329	Antibiotic biosynthesis monooxygenase
FORC48_RS08770	COG0583	DNA-binding transcription factor activity
FORC48_RS08790	COG1234	tRNA 3'-trailer cleavage
FORC48_RS08820	COG0406	alpha-ribazole phosphatase activity
FORC48_RS08850	COG0367	asparagine synthase
FORC48_RS08880	COG1802	Transcriptional regulator
FORC48_RS08885	COG0697	spore germination
FORC48_RS08895	COG0523	cobalamin synthesis protein
FORC48_RS08905	COG0701	Predicted permease
FORC48_RS08920	COG1757	Na H antiporter
FORC48_RS08925	COG0789	Transcriptional regulator
FORC48_RS08950	COG0534	Mate efflux family protein
FORC48_RS08955	COG3340	Belongs to the peptidase S51 family
FORC48_RS08975	COG0785	Cytochrome C biogenesis protein
FORC48_RS08980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_RS09000	COG2733	membrane
FORC48_RS09040	COG1131	(ABC) transporter
FORC48_RS09060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC48_RS09065	COG0528	UMP kinase activity
FORC48_RS09075	COG1027	Aspartate ammonia-lyase
FORC48_RS09080	COG0281	malic enzyme
FORC48_RS09085	COG4191	Histidine kinase
FORC48_RS09090	COG0784	Response regulator, receiver
FORC48_RS09095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC48_RS09115	COG3620	sequence-specific DNA binding
FORC48_RS09155	COG2814	Major facilitator Superfamily
FORC48_RS09180	COG0477	Major facilitator Superfamily
FORC48_RS09195	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC48_RS09200	COG2223	nitrite transmembrane transporter activity
FORC48_RS09205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC48_RS09225	COG0733	neurotransmitter:sodium symporter activity
FORC48_RS09235	COG5566	PFAM Mor transcription activator
FORC48_RS09240	COG2323	membrane
FORC48_RS09270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC48_RS09280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_RS09285	COG0028	Belongs to the TPP enzyme family
FORC48_RS09305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FORC48_RS09330	COG2814	Major facilitator Superfamily
FORC48_RS09335	COG3384	dioxygenase
FORC48_RS09345	COG3279	Response regulator of the LytR AlgR family
FORC48_RS09350	COG0427	acetyl-CoA hydrolase
FORC48_RS09370	COG4166	transmembrane transport
FORC48_RS09375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS09395	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC48_RS09410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC48_RS09415	COG0531	amino acid
FORC48_RS09450	COG2309	aminopeptidase activity
FORC48_RS09465	COG0456	acetyltransferase
FORC48_RS09480	COG1266	CAAX protease self-immunity
FORC48_RS09485	COG1309	transcriptional regulator
FORC48_RS09490	COG2390	Transcriptional regulator
FORC48_RS09500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS09505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC48_RS09515	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC48_RS09535	COG0583	DNA-binding transcription factor activity
FORC48_RS09550	COG0006	proline dipeptidase activity
FORC48_RS09560	COG2132	Multicopper oxidase
FORC48_RS09575	COG1309	transcriptional regulator
FORC48_RS09580	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FORC48_RS09640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC48_RS09660	COG1114	Component of the transport system for branched-chain amino acids
FORC48_RS09665	COG1910	domain protein
FORC48_RS09685	COG2318	DinB family
FORC48_RS09690	COG4122	O-methyltransferase activity
FORC48_RS09695	COG1280	lysine exporter protein (LysE YggA)
FORC48_RS09700	COG3403	YqcI/YcgG family
FORC48_RS09715	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC48_RS09720	COG0561	phosphatase activity
FORC48_RS09725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC48_RS09735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC48_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS09750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS09765	COG1276	copper resistance
FORC48_RS09765	COG2372	response to copper ion
FORC48_RS09770	COG4549	nuclear export factor GLE1
FORC48_RS09775	COG0697	spore germination
FORC48_RS09780	COG0583	DNA-binding transcription factor activity
FORC48_RS09785	COG1959	2 iron, 2 sulfur cluster binding
FORC48_RS09790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FORC48_RS09795	COG0778	Nitroreductase
FORC48_RS09810	COG0628	permease
FORC48_RS09820	COG1231	oxidoreductase activity
FORC48_RS09830	COG0523	cobalamin synthesis protein
FORC48_RS09840	COG0411	ABC transporter
FORC48_RS09860	COG0583	DNA-binding transcription factor activity
FORC48_RS09890	COG1271	oxidase subunit
FORC48_RS09895	COG1294	oxidase, subunit
FORC48_RS09900	COG4988	ABC transporter
FORC48_RS09905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC48_RS09915	COG1216	Glycosyl transferase, family 2
FORC48_RS09955	COG1686	Belongs to the peptidase S11 family
FORC48_RS09970	COG0791	NLP P60 protein
FORC48_RS09970	COG1388	LysM domain
FORC48_RS09980	COG1132	(ABC) transporter
FORC48_RS09985	COG0745	RESPONSE REGULATOR receiver
FORC48_RS09990	COG5002	protein histidine kinase activity
FORC48_RS09995	COG0300	oxidoreductase activity
FORC48_RS10025	COG0460	homoserine dehydrogenase
FORC48_RS10050	COG1316	TRANSCRIPTIONal
FORC48_RS10060	COG0745	RESPONSE REGULATOR receiver
FORC48_RS10065	COG5002	protein histidine kinase activity
FORC48_RS10080	COG1285	pathogenesis
FORC48_RS10085	COG1247	-acetyltransferase
FORC48_RS10105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC48_RS10115	COG1082	Xylose isomerase domain protein TIM barrel
FORC48_RS10125	COG2814	Major facilitator Superfamily
FORC48_RS10130	COG1279	arginine transmembrane transporter activity
FORC48_RS10135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS10145	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC48_RS10180	COG0577	efflux transmembrane transporter activity
FORC48_RS10185	COG2002	toxin-antitoxin pair type II binding
FORC48_RS10190	COG1404	Belongs to the peptidase S8 family
FORC48_RS10195	COG0640	Transcriptional regulator
FORC48_RS10200	COG0667	Aldo Keto reductase
FORC48_RS10205	COG2814	Major facilitator Superfamily
FORC48_RS10215	COG3152	Membrane
FORC48_RS10240	COG0840	transmembrane signaling receptor activity
FORC48_RS10260	COG3949	Membrane
FORC48_RS10265	COG0783	Belongs to the Dps family
FORC48_RS10280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC48_RS10290	COG1231	oxidoreductase activity
FORC48_RS10295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS10300	COG4989	oxidoreductase activity
FORC48_RS10305	COG0523	cobalamin synthesis protein
FORC48_RS10310	COG0456	acetyltransferase
FORC48_RS10315	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC48_RS10325	COG0702	epimerase
FORC48_RS10335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC48_RS10345	COG4166	transmembrane transport
FORC48_RS10370	COG5337	Spore coat protein CotH
FORC48_RS10375	COG1051	belongs to the nudix hydrolase family
FORC48_RS10380	COG0586	Pfam SNARE associated Golgi protein
FORC48_RS10385	COG2244	polysaccharide biosynthetic process
FORC48_RS10395	COG0701	Predicted permease
FORC48_RS10400	COG3689	TIGRFAM TIGR03943 family protein
FORC48_RS10405	COG1607	acyl-coa hydrolase
FORC48_RS10415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC48_RS10430	COG0702	epimerase
FORC48_RS10435	COG2839	Protein conserved in bacteria
FORC48_RS10440	COG1253	flavin adenine dinucleotide binding
FORC48_RS10455	COG1114	Component of the transport system for branched-chain amino acids
FORC48_RS10460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC48_RS10480	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS10490	COG1876	peptidase activity
FORC48_RS10500	COG0154	amidase activity
FORC48_RS10505	COG2211	Major facilitator Superfamily
FORC48_RS10530	COG0561	phosphatase activity
FORC48_RS10545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC48_RS10565	COG1819	glycosyl
FORC48_RS10570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS10575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS10605	COG0456	acetyltransferase
FORC48_RS10640	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC48_RS10725	COG3874	Sporulation protein YtfJ
FORC48_RS10750	COG2226	methyltransferase
FORC48_RS10775	COG0346	lactoylglutathione lyase activity
FORC48_RS10785	COG0604	alcohol dehydrogenase
FORC48_RS10790	COG1595	DNA-templated transcription, initiation
FORC48_RS10815	COG0386	Belongs to the glutathione peroxidase family
FORC48_RS10820	COG1305	Transglutaminase-like
FORC48_RS10825	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FORC48_RS10830	COG0714	Associated with various cellular activities
FORC48_RS10835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FORC48_RS10840	COG1140	nitrate reductase beta subunit
FORC48_RS10845	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FORC48_RS10850	COG2181	nitrate reductase activity
FORC48_RS10855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_RS10860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC48_RS10865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_RS10870	COG0303	'Molybdopterin
FORC48_RS10875	COG0314	molybdopterin synthase activity
FORC48_RS10885	COG2223	nitrite transmembrane transporter activity
FORC48_RS10910	COG1648	precorrin-2 dehydrogenase activity
FORC48_RS10920	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC48_RS10920	COG1587	Uroporphyrinogen-III synthase
FORC48_RS10925	COG2146	nitrite reductase [NAD(P)H] activity
FORC48_RS10930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC48_RS10970	COG2359	stage V sporulation protein S
FORC48_RS10985	COG2801	Transposase and inactivated derivatives
FORC48_RS11000	COG0457	Tetratricopeptide repeat
FORC48_RS11015	COG1418	mRNA catabolic process
FORC48_RS11020	COG0488	(ABC) transporter
FORC48_RS11035	COG0629	single-stranded DNA binding
FORC48_RS11050	COG1413	lyase activity
FORC48_RS11065	COG2136	Putative SAM-dependent methyltransferase
FORC48_RS11065	COG2521	methyltransferase
FORC48_RS11070	COG0018	arginyl-trna synthetase
FORC48_RS11130	COG0017	Asparaginyl-tRNA synthetase
FORC48_RS11135	COG0733	neurotransmitter:sodium symporter activity
FORC48_RS11160	COG2610	gluconate transmembrane transporter activity
FORC48_RS11170	COG1794	racemase activity, acting on amino acids and derivatives
FORC48_RS11180	COG0456	acetyltransferase
FORC48_RS11190	COG3655	Transcriptional regulator
FORC48_RS11195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC48_RS11205	COG1131	(ABC) transporter
FORC48_RS11210	COG4473	ABC transporter
FORC48_RS11220	COG0546	phosphoglycolate phosphatase activity
FORC48_RS11235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_RS11250	COG0768	penicillin binding
FORC48_RS11260	COG0204	Acyl-transferase
FORC48_RS11265	COG1272	protein, Hemolysin III
FORC48_RS11275	COG0805	protein transport
FORC48_RS11285	COG1307	EDD domain protein, DegV family
FORC48_RS11295	COG1999	signal sequence binding
FORC48_RS11300	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC48_RS11305	COG0367	asparagine synthase
FORC48_RS11320	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS11325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS11330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC48_RS11350	COG1335	isochorismatase
FORC48_RS11365	COG0668	transmembrane transport
FORC48_RS11370	COG4585	Histidine kinase
FORC48_RS11370	COG2203	Gaf domain
FORC48_RS11375	COG2197	response regulator
FORC48_RS11380	COG1737	Transcriptional regulator
FORC48_RS11385	COG0384	phenazine biosynthesis protein PhzF
FORC48_RS11390	COG1064	alcohol dehydrogenase
FORC48_RS11400	COG2801	Transposase and inactivated derivatives
FORC48_RS11425	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC48_RS11460	COG1125	glycine betaine transport
FORC48_RS11460	COG0517	IMP dehydrogenase activity
FORC48_RS11465	COG1174	glycine betaine transport
FORC48_RS11500	COG1253	flavin adenine dinucleotide binding
FORC48_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS11510	COG5506	Protein of unknown function (DUF1694)
FORC48_RS11530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC48_RS11535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FORC48_RS11540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FORC48_RS11545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC48_RS11550	COG0456	acetyltransferase
FORC48_RS11555	COG3829	transcription factor binding
FORC48_RS11560	COG1509	lysine 2,3-aminomutase activity
FORC48_RS11595	COG0515	serine threonine protein kinase
FORC48_RS11595	COG3064	Membrane
FORC48_RS11595	COG4991	sh3 domain protein
FORC48_RS11605	COG0671	phosphoesterase, PA-phosphatase related
FORC48_RS11610	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC48_RS11615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_RS11690	COG0300	oxidoreductase activity
FORC48_RS11710	COG4499	WXG100 protein secretion system (Wss), protein YukC
FORC48_RS11710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_RS11720	COG2814	Major facilitator Superfamily
FORC48_RS11725	COG4841	protein insertion into membrane
FORC48_RS11730	COG0372	Belongs to the citrate synthase family
FORC48_RS11735	COG2079	MmgE PrpD family protein
FORC48_RS11740	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC48_RS11745	COG1960	acyl-CoA dehydrogenase activity
FORC48_RS11750	COG2084	Dehydrogenase
FORC48_RS11760	COG1280	lysine exporter protein (LysE YggA)
FORC48_RS11765	COG1024	Enoyl-CoA hydratase
FORC48_RS11780	COG0420	3'-5' exonuclease activity
FORC48_RS11785	COG0419	ATPase involved in DNA repair
FORC48_RS11820	COG2223	nitrite transmembrane transporter activity
FORC48_RS11830	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS11835	COG1169	isochorismate synthase
FORC48_RS11840	COG1021	2,3-dihydroxybenzoate-AMP ligase
FORC48_RS11845	COG3433	isochorismatase activity
FORC48_RS11845	COG1535	isochorismatase
FORC48_RS11850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FORC48_RS11855	COG3251	PFAM MbtH domain protein
FORC48_RS11860	COG2814	Major facilitator Superfamily
FORC48_RS11875	COG0776	regulation of translation
FORC48_RS11885	COG2318	DinB family
FORC48_RS11895	COG1115	amino acid carrier protein
FORC48_RS11925	COG1187	pseudouridine synthase activity
FORC48_RS11930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC48_RS11935	COG1136	(ABC) transporter
FORC48_RS11950	COG2814	Major facilitator Superfamily
FORC48_RS11965	COG0028	Belongs to the TPP enzyme family
FORC48_RS12005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_RS12025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS12055	COG1247	-acetyltransferase
FORC48_RS12080	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FORC48_RS12095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS12125	COG0583	DNA-binding transcription factor activity
FORC48_RS12130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC48_RS12150	COG0583	DNA-binding transcription factor activity
FORC48_RS12155	COG2258	MOSC domain
FORC48_RS12170	COG1132	(ABC) transporter
FORC48_RS12175	COG1132	(ABC) transporter
FORC48_RS12215	COG1396	sequence-specific DNA binding
FORC48_RS12245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC48_RS12250	COG1595	DNA-templated transcription, initiation
FORC48_RS12275	COG1649	PFAM Uncharacterised BCR, COG1649
FORC48_RS12300	COG2971	BadF BadG BcrA BcrD
FORC48_RS12320	COG1846	Transcriptional regulator
FORC48_RS12335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS12355	COG1309	transcriptional regulator
FORC48_RS12375	COG3615	Tellurite resistance protein tehB
FORC48_RS12375	COG0500	methyltransferase
FORC48_RS12385	COG2226	methyltransferase
FORC48_RS12390	COG3961	Belongs to the TPP enzyme family
FORC48_RS12395	COG1846	Transcriptional regulator
FORC48_RS12430	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC48_RS12460	COG2002	toxin-antitoxin pair type II binding
FORC48_RS12470	COG0730	response to heat
FORC48_RS12480	COG1686	Belongs to the peptidase S11 family
FORC48_RS12490	COG2814	Major facilitator Superfamily
FORC48_RS12535	COG2312	Erythromycin esterase
FORC48_RS12540	COG2312	Erythromycin esterase
FORC48_RS12550	COG0741	lytic transglycosylase activity
FORC48_RS12555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS12620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_RS12625	COG0768	penicillin binding
FORC48_RS12630	COG1595	DNA-templated transcription, initiation
FORC48_RS12640	COG0768	penicillin binding
FORC48_RS12645	COG0768	penicillin binding
FORC48_RS12655	COG1408	metallophosphoesterase
FORC48_RS12665	COG1131	(ABC) transporter
FORC48_RS12675	COG1309	transcriptional regulator
FORC48_RS12690	COG1960	acyl-CoA dehydrogenase activity
FORC48_RS12695	COG0439	Biotin carboxylase
FORC48_RS12700	COG0511	ligase activity, forming carbon-carbon bonds
FORC48_RS12705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC48_RS12710	COG1024	Enoyl-CoA hydratase
FORC48_RS12715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC48_RS12720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC48_RS12755	COG1686	Belongs to the peptidase S11 family
FORC48_RS12785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC48_RS12800	COG3227	Zinc metalloprotease (Elastase)
FORC48_RS12805	COG2207	Transcriptional regulator
FORC48_RS12835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC48_RS12845	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS12850	COG1733	regulation of RNA biosynthetic process
FORC48_RS12870	COG1942	4-Oxalocrotonate Tautomerase
FORC48_RS12875	COG0583	DNA-binding transcription factor activity
FORC48_RS12900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS12905	COG2368	4-hydroxyphenylacetate
FORC48_RS12920	COG1063	alcohol dehydrogenase
FORC48_RS12930	COG2323	membrane
FORC48_RS12945	COG3386	PFAM SMP-30 Gluconolaconase
FORC48_RS12960	COG3773	Cell wall hydrolase
FORC48_RS12970	COG0745	RESPONSE REGULATOR receiver
FORC48_RS12975	COG2205	protein histidine kinase activity
FORC48_RS12985	COG0488	(ABC) transporter
FORC48_RS13000	COG0825	malonyl-CoA metabolic process
FORC48_RS13010	COG1136	(ABC) transporter
FORC48_RS13015	COG0577	efflux transmembrane transporter activity
FORC48_RS13035	COG0460	homoserine dehydrogenase
FORC48_RS13040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS13050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC48_RS13080	COG0582	viral genome integration into host DNA
FORC48_RS13220	COG0582	viral genome integration into host DNA
FORC48_RS13340	COG4824	toxin secretion phage lysis holin
FORC48_RS13400	COG2124	cytochrome p450
FORC48_RS13440	COG0561	phosphatase activity
FORC48_RS13450	COG5002	protein histidine kinase activity
FORC48_RS13455	COG0768	penicillin binding
FORC48_RS13465	COG1819	glycosyl
FORC48_RS13470	COG1794	racemase activity, acting on amino acids and derivatives
FORC48_RS13495	COG2205	protein histidine kinase activity
FORC48_RS13500	COG0582	viral genome integration into host DNA
FORC48_RS13545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC48_RS13550	COG0604	alcohol dehydrogenase
FORC48_RS13555	COG0671	phosphoesterase, PA-phosphatase related
FORC48_RS13560	COG0768	penicillin binding
FORC48_RS13610	COG2814	Major facilitator Superfamily
FORC48_RS13615	COG0789	Transcriptional regulator
FORC48_RS13615	COG4978	Transcriptional regulator
FORC48_RS13640	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_RS13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS13665	COG0697	spore germination
FORC48_RS13700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_RS13710	COG2223	nitrite transmembrane transporter activity
FORC48_RS13725	COG0592	DNA-directed DNA polymerase activity
FORC48_RS13745	COG3878	Protein conserved in bacteria
FORC48_RS13755	COG3507	Belongs to the glycosyl hydrolase 43 family
FORC48_RS13755	COG3693	PFAM glycoside hydrolase, family 10
FORC48_RS13755	COG2382	esterase
FORC48_RS13775	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC48_RS13815	COG0322	excinuclease ABC activity
FORC48_RS13855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_RS13890	COG1011	Hydrolase
FORC48_RS13895	COG0745	RESPONSE REGULATOR receiver
FORC48_RS13900	COG5002	protein histidine kinase activity
FORC48_RS13915	COG1136	(ABC) transporter
FORC48_RS13920	COG0577	efflux transmembrane transporter activity
FORC48_RS13925	COG1073	alpha beta
FORC48_RS13930	COG0657	acetylesterase activity
FORC48_RS13935	COG0076	glutamate decarboxylase activity
FORC48_RS13950	COG1523	belongs to the glycosyl hydrolase 13 family
FORC48_RS13955	COG3227	Zinc metalloprotease (Elastase)
FORC48_RS13960	COG0737	Belongs to the 5'-nucleotidase family
FORC48_RS13975	COG0201	protein transport
FORC48_RS13980	COG0697	spore germination
FORC48_RS13985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS13995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC48_RS14025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS14040	COG2959	enzyme of heme biosynthesis
FORC48_RS14080	COG1309	transcriptional regulator
FORC48_RS14105	COG3284	Transcriptional regulator
FORC48_RS14125	COG1349	DNA-binding transcription factor activity
FORC48_RS14140	COG1959	2 iron, 2 sulfur cluster binding
FORC48_RS14155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC48_RS14160	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC48_RS14165	COG0022	dehydrogenase e1 component
FORC48_RS14170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC48_RS14180	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS14185	COG0456	acetyltransferase
FORC48_RS14185	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC48_RS14225	COG4176	ABC-type proline glycine betaine transport system permease component
FORC48_RS14230	COG4175	Glycine betaine
FORC48_RS14230	COG0517	IMP dehydrogenase activity
FORC48_RS14260	COG2153	protein acetylation
FORC48_RS14265	COG3397	chitin binding
FORC48_RS14270	COG1819	glycosyl
FORC48_RS14285	COG2205	protein histidine kinase activity
FORC48_RS14290	COG2226	methyltransferase
FORC48_RS14295	COG2315	Protein conserved in bacteria
FORC48_RS14340	COG3973	AAA domain
FORC48_RS14355	COG0514	ATP-dependent DNA helicase (RecQ)
FORC48_RS14390	COG4637	Psort location Cytoplasmic, score
FORC48_RS14405	COG3397	chitin binding
FORC48_RS14420	COG1162	GTPase activity
FORC48_RS14425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC48_RS14430	COG1115	amino acid carrier protein
FORC48_RS14435	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS14440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC48_RS14450	COG3938	Belongs to the proline racemase family
FORC48_RS14455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC48_RS14500	COG1078	dGTPase activity
FORC48_RS14505	COG0586	Pfam SNARE associated Golgi protein
FORC48_RS14515	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FORC48_RS14525	COG4166	transmembrane transport
FORC48_RS14535	COG4948	Mandelate Racemase Muconate Lactonizing
FORC48_RS14550	COG0667	Aldo Keto reductase
FORC48_RS14595	COG3850	Histidine kinase
FORC48_RS14595	COG5002	protein histidine kinase activity
FORC48_RS14600	COG0745	RESPONSE REGULATOR receiver
FORC48_RS14635	COG1164	Oligoendopeptidase f
FORC48_RS14640	COG1307	EDD domain protein, DegV family
FORC48_RS14680	COG2814	Major facilitator Superfamily
FORC48_RS14690	COG1664	Polymer-forming cytoskeletal
FORC48_RS14695	COG0789	Transcriptional regulator
FORC48_RS14700	COG4533	DNA binding
FORC48_RS14705	COG0477	Major facilitator Superfamily
FORC48_RS14705	COG2814	Major facilitator Superfamily
FORC48_RS14725	COG2261	transglycosylase associated protein
FORC48_RS14740	COG2226	methyltransferase
FORC48_RS14780	COG0436	Aminotransferase
FORC48_RS14785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC48_RS14795	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FORC48_RS14840	COG0628	permease
FORC48_RS14855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FORC48_RS14860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_RS14865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_RS14905	COG2746	aminoglycoside 3-N-acetyltransferase activity
FORC48_RS14915	COG0697	spore germination
FORC48_RS14925	COG2318	DinB family
FORC48_RS14945	COG4912	Dna alkylation repair
FORC48_RS14950	COG0346	lactoylglutathione lyase activity
FORC48_RS14970	COG0861	Integral membrane protein TerC family
FORC48_RS14975	COG1368	sulfuric ester hydrolase activity
FORC48_RS14980	COG0488	(ABC) transporter
FORC48_RS14985	COG2409	Drug exporters of the RND superfamily
FORC48_RS14985	COG1033	growth of symbiont in host cell
FORC48_RS14990	COG1309	transcriptional regulator
FORC48_RS15005	COG0287	Prephenate dehydrogenase
FORC48_RS15025	COG1605	Chorismate mutase
FORC48_RS15025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC48_RS15070	COG3584	3D domain protein
FORC48_RS15070	COG1388	LysM domain
FORC48_RS15080	COG0346	lactoylglutathione lyase activity
FORC48_RS15085	COG0277	FAD linked oxidase domain protein
FORC48_RS15115	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC48_RS15120	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC48_RS15130	COG2390	Transcriptional regulator
FORC48_RS15135	COG1070	Carbohydrate kinase
FORC48_RS15160	COG2329	Antibiotic biosynthesis monooxygenase
FORC48_RS15180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS15200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_RS15205	COG4187	Peptidase family M20/M25/M40
FORC48_RS15210	COG1414	Transcriptional regulator
FORC48_RS15220	COG0833	amino acid
FORC48_RS15230	COG3239	Fatty acid desaturase
FORC48_RS15240	COG2720	vancomycin resistance protein
FORC48_RS15245	COG1785	Belongs to the alkaline phosphatase family
FORC48_RS15255	COG3655	Transcriptional regulator
FORC48_RS15275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS15280	COG0346	lactoylglutathione lyase activity
FORC48_RS15305	COG0714	Associated with various cellular activities
FORC48_RS15330	COG0463	Glycosyl transferase, family 2
FORC48_RS15360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC48_RS15365	COG0753	catalase activity
FORC48_RS15405	COG0714	Associated with various cellular activities
FORC48_RS15450	COG2801	Transposase and inactivated derivatives
FORC48_RS15460	COG0778	Nitroreductase
FORC48_RS15465	COG1846	Transcriptional regulator
FORC48_RS15490	COG4884	unkown
FORC48_RS15490	COG3831	ATPase activity
FORC48_RS15495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_RS15515	COG0456	acetyltransferase
FORC48_RS15530	COG0697	spore germination
FORC48_RS15535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS15585	COG0730	response to heat
FORC48_RS15595	COG0833	amino acid
FORC48_RS15605	COG4335	DNA alkylation repair
FORC48_RS15650	COG0768	penicillin binding
FORC48_RS15680	COG1984	allophanate hydrolase subunit 2
FORC48_RS15685	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC48_RS15690	COG1414	Transcriptional regulator
FORC48_RS15705	COG0640	Transcriptional regulator
FORC48_RS15715	COG1960	acyl-CoA dehydrogenase activity
FORC48_RS15730	COG3314	Sporulation integral membrane protein YlbJ
FORC48_RS15750	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FORC48_RS15775	COG0574	Belongs to the PEP-utilizing enzyme family
FORC48_RS15775	COG3848	Pyruvate phosphate dikinase
FORC48_RS15780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS15800	COG1063	alcohol dehydrogenase
FORC48_RS15805	COG1027	Aspartate ammonia-lyase
FORC48_RS15810	COG0252	asparaginase activity
FORC48_RS15815	COG1396	sequence-specific DNA binding
FORC48_RS15850	COG5002	protein histidine kinase activity
FORC48_RS15875	COG2207	Transcriptional regulator
FORC48_RS15895	COG0322	excinuclease ABC activity
FORC48_RS15900	COG0531	amino acid
FORC48_RS15905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_RS15915	COG0281	malic enzyme
FORC48_RS15930	COG0531	amino acid
FORC48_RS15935	COG0697	spore germination
FORC48_RS15945	COG0784	Response regulator, receiver
FORC48_RS15950	COG4191	Histidine kinase
FORC48_RS15960	COG1115	amino acid carrier protein
FORC48_RS15985	COG0737	Belongs to the 5'-nucleotidase family
FORC48_RS15990	COG2267	carboxylic ester hydrolase activity
FORC48_RS15995	COG1335	isochorismatase
FORC48_RS16015	COG0583	DNA-binding transcription factor activity
FORC48_RS16025	COG0598	Magnesium transport protein CorA
FORC48_RS16045	COG1073	alpha beta
FORC48_RS16065	COG0415	Belongs to the DNA photolyase family
FORC48_RS16075	COG2814	Major facilitator Superfamily
FORC48_RS16085	COG0657	acetylesterase activity
FORC48_RS16090	COG0288	reversible hydration of carbon dioxide
FORC48_RS16100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC48_RS16105	COG5609	conserved protein (DUF2294)
FORC48_RS16110	COG2814	Major facilitator Superfamily
FORC48_RS16120	COG2814	Major facilitator Superfamily
FORC48_RS16125	COG0583	DNA-binding transcription factor activity
FORC48_RS16140	COG2801	Transposase and inactivated derivatives
FORC48_RS16145	COG5294	Protein conserved in bacteria
FORC48_RS16155	COG0456	acetyltransferase
FORC48_RS16160	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC48_RS16170	COG0798	PFAM Bile acid sodium symporter
FORC48_RS16175	COG0346	lactoylglutathione lyase activity
FORC48_RS16180	COG0640	Transcriptional regulator
FORC48_RS16195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC48_RS16195	COG3320	Male sterility
FORC48_RS16215	COG0346	lactoylglutathione lyase activity
FORC48_RS16235	COG0745	RESPONSE REGULATOR receiver
FORC48_RS16240	COG5002	protein histidine kinase activity
FORC48_RS16240	COG3850	Histidine kinase
FORC48_RS16285	COG0277	FAD linked oxidase domain protein
FORC48_RS16300	COG1136	(ABC) transporter
FORC48_RS16340	COG2814	Major facilitator Superfamily
FORC48_RS16360	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FORC48_RS16380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC48_RS16400	COG0577	efflux transmembrane transporter activity
FORC48_RS16420	COG5002	protein histidine kinase activity
FORC48_RS16420	COG3850	Histidine kinase
FORC48_RS16430	COG2364	Membrane
FORC48_RS16435	COG1846	Transcriptional regulator
FORC48_RS16440	COG0456	acetyltransferase
FORC48_RS16445	COG2808	Putative FMN-binding domain
FORC48_RS16450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS16485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC48_RS16530	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_RS16530	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS16585	COG5444	nuclease activity
FORC48_RS16630	COG5444	nuclease activity
FORC48_RS16685	COG1876	peptidase activity
FORC48_RS16690	COG2843	Capsule synthesis protein
FORC48_RS16700	COG0477	Major facilitator Superfamily
FORC48_RS16715	COG1846	Transcriptional regulator
FORC48_RS16720	COG2814	Major facilitator Superfamily
FORC48_RS16735	COG2031	fatty acid transporter
FORC48_RS16745	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC48_RS16800	COG1288	antiporter activity
FORC48_RS16805	COG2356	endonuclease I
FORC48_RS16825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC48_RS16845	COG1733	regulation of RNA biosynthetic process
FORC48_RS16850	COG0778	Nitroreductase
FORC48_RS16860	COG0469	pyruvate kinase activity
FORC48_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS16895	COG1131	(ABC) transporter
FORC48_RS16920	COG1011	Hydrolase
FORC48_RS16925	COG2365	Tyrosine phosphatase family
FORC48_RS16960	COG0628	permease
FORC48_RS16990	COG0500	methyltransferase
FORC48_RS17000	COG0477	Major facilitator Superfamily
FORC48_RS17030	COG1253	flavin adenine dinucleotide binding
FORC48_RS17035	COG0789	Transcriptional regulator
FORC48_RS17045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC48_RS17075	COG0697	spore germination
FORC48_RS17085	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC48_RS17090	COG3813	Protein conserved in bacteria
FORC48_RS17095	COG2706	6-phosphogluconolactonase activity
FORC48_RS17100	COG1070	Carbohydrate kinase
FORC48_RS17110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC48_RS17115	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FORC48_RS17120	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC48_RS17125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC48_RS17170	COG0814	amino acid
FORC48_RS17205	COG2188	Transcriptional regulator
FORC48_RS17210	COG0673	inositol 2-dehydrogenase activity
FORC48_RS17230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS17255	COG0384	phenazine biosynthesis protein PhzF
FORC48_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS17280	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_RS17285	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC48_RS17290	COG1733	regulation of RNA biosynthetic process
FORC48_RS17315	COG1191	sigma factor activity
FORC48_RS17340	COG1280	lysine exporter protein (LysE YggA)
FORC48_RS17385	COG1151	hydroxylamine reductase activity
FORC48_RS17400	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_RS17400	COG3757	hydrolase, family 25
FORC48_RS17435	COG2072	flavoprotein involved in K transport
FORC48_RS17475	COG1113	amino acid transport
FORC48_RS17480	COG2814	Major facilitator Superfamily
FORC48_RS17520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FORC48_RS17525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC48_RS17535	COG1247	-acetyltransferase
FORC48_RS17540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS17545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS17550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS17555	COG3739	integral membrane protein
FORC48_RS17575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS17590	COG0583	DNA-binding transcription factor activity
FORC48_RS17620	COG1193	negative regulation of DNA recombination
FORC48_RS17630	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC48_RS17635	COG1164	Oligoendopeptidase f
FORC48_RS17655	COG3781	membrane
FORC48_RS17670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FORC48_RS17695	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_RS17705	COG0640	Transcriptional regulator
FORC48_RS17710	COG0604	alcohol dehydrogenase
FORC48_RS17725	COG0457	Tetratricopeptide repeat
FORC48_RS17740	COG0277	FAD linked oxidase domain protein
FORC48_RS17760	COG1183	phosphatidylcholine synthase activity
FORC48_RS17775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS17775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS17780	COG1252	NADH dehydrogenase
FORC48_RS17795	COG0823	Involved in the tonB-independent uptake of proteins
FORC48_RS17800	COG3397	chitin binding
FORC48_RS17810	COG0697	spore germination
FORC48_RS17830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC48_RS17840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC48_RS17850	COG0457	Tetratricopeptide repeat
FORC48_RS17915	COG0488	(ABC) transporter
FORC48_RS17945	COG3852	Histidine kinase
FORC48_RS17955	COG1285	pathogenesis
FORC48_RS17965	COG2514	catechol 2,3-dioxygenase activity
FORC48_RS17970	COG2720	vancomycin resistance protein
FORC48_RS18010	COG0716	FMN binding
FORC48_RS18020	COG0494	nUDIX hydrolase
FORC48_RS18040	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS18050	COG0165	Argininosuccinate lyase
FORC48_RS18065	COG4145	pantothenate transmembrane transporter activity
FORC48_RS18075	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS18090	COG1657	PFAM Prenyltransferase squalene oxidase
FORC48_RS18095	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FORC48_RS18100	COG2962	Rard protein
FORC48_RS18105	COG3326	Membrane
FORC48_RS18120	COG0489	protein tyrosine kinase activity
FORC48_RS18130	COG0314	molybdopterin synthase activity
FORC48_RS18135	COG0303	'Molybdopterin
FORC48_RS18140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_RS18145	COG2116	formate transmembrane transporter activity
FORC48_RS18160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC48_RS18165	COG5609	conserved protein (DUF2294)
FORC48_RS18170	COG2427	Protein of unknown function (DUF1641)
FORC48_RS18175	COG3383	formate dehydrogenase (NAD+) activity
FORC48_RS18185	COG0697	spore germination
FORC48_RS18200	COG0531	amino acid
FORC48_RS18235	COG2226	methyltransferase
FORC48_RS18240	COG4166	transmembrane transport
FORC48_RS18245	COG4166	transmembrane transport
FORC48_RS18250	COG4166	transmembrane transport
FORC48_RS18255	COG1301	dicarboxylic acid transport
FORC48_RS18260	COG1316	TRANSCRIPTIONal
FORC48_RS18270	COG1595	DNA-templated transcription, initiation
FORC48_RS18280	COG1131	(ABC) transporter
FORC48_RS18290	COG0673	inositol 2-dehydrogenase activity
FORC48_RS18295	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC48_RS18300	COG0187	DNA topoisomerase II activity
FORC48_RS18310	COG1832	CoA-binding protein
FORC48_RS18315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC48_RS18320	COG0745	RESPONSE REGULATOR receiver
FORC48_RS18340	COG4841	protein insertion into membrane
FORC48_RS18345	COG0824	Thioesterase
FORC48_RS18375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_RS18390	COG1132	(ABC) transporter
FORC48_RS18395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FORC48_RS18425	COG2211	Major facilitator Superfamily
FORC48_RS18435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC48_RS18450	COG0183	Belongs to the thiolase family
FORC48_RS18455	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_RS18460	COG1268	BioY protein
FORC48_RS18465	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_RS18510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS18525	COG5002	protein histidine kinase activity
FORC48_RS18530	COG0400	carboxylic ester hydrolase activity
FORC48_RS18535	COG0346	lactoylglutathione lyase activity
FORC48_RS18540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC48_RS18550	COG0069	glutamate synthase activity
FORC48_RS18555	COG1902	pentaerythritol trinitrate reductase activity
FORC48_RS18560	COG1329	Transcriptional regulator
FORC48_RS18565	COG0010	Belongs to the arginase family
FORC48_RS18620	COG4846	Membrane protein involved in cytochrome C biogenesis
FORC48_RS18625	COG0785	Cytochrome C biogenesis protein
FORC48_RS18640	COG1473	amidohydrolase
FORC48_RS18650	COG1131	(ABC) transporter
FORC48_RS18665	COG0583	DNA-binding transcription factor activity
FORC48_RS18675	COG1346	cytolysis
FORC48_RS18690	COG0730	response to heat
FORC48_RS18715	COG1132	(ABC) transporter
FORC48_RS18720	COG1132	(ABC) transporter
FORC48_RS18745	COG3639	organic phosphonate transmembrane transporter activity
FORC48_RS18760	COG0737	Belongs to the 5'-nucleotidase family
FORC48_RS18770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FORC48_RS18790	COG1695	Transcriptional regulator
FORC48_RS18800	COG0739	heme binding
FORC48_RS18805	COG0741	lytic transglycosylase activity
FORC48_RS18835	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC48_RS18870	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS18890	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_RS18890	COG1388	LysM domain
FORC48_RS18890	COG5632	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS18895	COG4824	toxin secretion phage lysis holin
FORC48_RS19050	COG1595	DNA-templated transcription, initiation
FORC48_RS19085	COG0270	DNA (cytosine-5-)-methyltransferase activity
FORC48_RS19170	COG1396	sequence-specific DNA binding
FORC48_RS19190	COG0174	glutamine synthetase
FORC48_RS19195	COG0789	Transcriptional regulator
FORC48_RS19200	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FORC48_RS19205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC48_RS19210	COG2860	membrane
FORC48_RS19215	COG0464	growth
FORC48_RS19245	COG3584	3D domain protein
FORC48_RS19245	COG1388	LysM domain
FORC48_RS19255	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC48_RS19255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC48_RS19255	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC48_RS19260	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC48_RS19265	COG1349	DNA-binding transcription factor activity
FORC48_RS19270	COG1979	alcohol dehydrogenase
FORC48_RS19275	COG2322	membrane
FORC48_RS19290	COG1113	amino acid transport
FORC48_RS19305	COG1408	metallophosphoesterase
FORC48_RS19310	COG2116	formate transmembrane transporter activity
FORC48_RS19325	COG2217	Heavy metal translocating P-type atpase
FORC48_RS19330	COG2608	mercury ion transmembrane transporter activity
FORC48_RS19335	COG1937	Protein conserved in bacteria
FORC48_RS19345	COG2819	hydrolase of the alpha beta superfamily
FORC48_RS19350	COG1120	ATPase activity
FORC48_RS19355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS19360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS19365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS19375	COG0708	Exodeoxyribonuclease III
FORC48_RS19380	COG2169	Transcriptional regulator
FORC48_RS19385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC48_RS19390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC48_RS19400	COG2364	Membrane
FORC48_RS19415	COG2267	carboxylic ester hydrolase activity
FORC48_RS19420	COG3300	MHYT domain
FORC48_RS19420	COG5001	Diguanylate cyclase
FORC48_RS19460	COG1346	cytolysis
FORC48_RS19470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC48_RS19480	COG2188	Transcriptional regulator
FORC48_RS19485	COG2723	6-phospho-beta-galactosidase activity
FORC48_RS19495	COG1404	Belongs to the peptidase S8 family
FORC48_RS19500	COG3773	Cell wall hydrolase
FORC48_RS19515	COG1368	sulfuric ester hydrolase activity
FORC48_RS19520	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FORC48_RS19545	COG4550	Control of competence regulator ComK, YlbF/YmcA
FORC48_RS19555	COG1013	pyruvate-flavodoxin oxidoreductase activity
FORC48_RS19560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FORC48_RS19560	COG0674	pyruvate-flavodoxin oxidoreductase activity
FORC48_RS19570	COG2359	stage V sporulation protein S
FORC48_RS19575	COG1692	metallophosphoesterase
FORC48_RS19595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC48_RS19600	COG1426	Protein conserved in bacteria
FORC48_RS19615	COG0300	oxidoreductase activity
FORC48_RS19620	COG0612	Peptidase, M16
FORC48_RS19625	COG0612	Peptidase, M16
FORC48_RS19630	COG1079	Belongs to the binding-protein-dependent transport system permease family
FORC48_RS19635	COG4603	Belongs to the binding-protein-dependent transport system permease family
FORC48_RS19640	COG3845	ABC transporter
FORC48_RS19645	COG1744	ABC transporter substrate-binding protein PnrA-like
FORC48_RS19650	COG2188	Transcriptional regulator
FORC48_RS19670	COG0740	serine-type endopeptidase activity
FORC48_RS19675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC48_RS19685	COG0527	aspartate kinase activity
FORC48_RS19690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC48_RS19695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC48_RS19700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC48_RS19705	COG1873	PFAM PRC-barrel domain
FORC48_RS19710	COG0612	Peptidase, M16
FORC48_RS19715	COG0726	polysaccharide deacetylase
FORC48_RS19730	COG0196	riboflavin kinase activity
FORC48_RS19740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC48_RS19745	COG1550	Protein conserved in bacteria
FORC48_RS19755	COG1358	cellular component organization or biogenesis
FORC48_RS19760	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FORC48_RS19765	COG0195	Participates in both transcription termination and antitermination
FORC48_RS19785	COG0750	zinc metalloprotease
FORC48_RS19795	COG4589	Belongs to the CDS family
FORC48_RS19840	COG4974	Belongs to the 'phage' integrase family
FORC48_RS19850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC48_RS19855	COG0758	DNA mediated transformation
FORC48_RS19860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FORC48_RS19900	COG1837	Belongs to the UPF0109 family
FORC48_RS19910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC48_RS19920	COG0552	protein localization to endoplasmic reticulum
FORC48_RS19925	COG1196	nuclear chromosome segregation
FORC48_RS19935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC48_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS19945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FORC48_RS19960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC48_RS19965	COG1461	Dihydroxyacetone kinase
FORC48_RS19970	COG1302	Protein conserved in bacteria
FORC48_RS19985	COG1564	THIamine pyrophosphokinase
FORC48_RS19990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC48_RS20000	COG2815	serine threonine protein kinase
FORC48_RS20000	COG0515	serine threonine protein kinase
FORC48_RS20005	COG0631	protein serine/threonine phosphatase activity
FORC48_RS20015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC48_RS20015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC48_RS20030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC48_RS20035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC48_RS20055	COG1561	YicC-like family, N-terminal region
FORC48_RS20060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FORC48_RS20070	COG0006	proline dipeptidase activity
FORC48_RS20085	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC48_RS20145	COG0564	pseudouridine synthase activity
FORC48_RS20165	COG3599	regulation of cell shape
FORC48_RS20170	COG2302	S4 RNA-binding domain
FORC48_RS20175	COG0762	integral membrane protein
FORC48_RS20185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC48_RS20195	COG1873	PFAM PRC-barrel domain
FORC48_RS20200	COG1191	sigma factor activity
FORC48_RS20205	COG1191	sigma factor activity
FORC48_RS20215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC48_RS20220	COG0849	cell division
FORC48_RS20240	COG0772	Belongs to the SEDS family
FORC48_RS20260	COG0768	penicillin binding
FORC48_RS20265	COG0768	penicillin binding
FORC48_RS20285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC48_RS20300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FORC48_RS20305	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC48_RS20315	COG3480	Lon protease (S16) C-terminal proteolytic domain
FORC48_RS20320	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC48_RS20325	COG3314	Sporulation integral membrane protein YlbJ
FORC48_RS20335	COG0742	ribosomal rna small subunit methyltransferase
FORC48_RS20350	COG3679	Belongs to the UPF0342 family
FORC48_RS20355	COG0406	alpha-ribazole phosphatase activity
FORC48_RS20370	COG2340	Cysteine-rich secretory protein family
FORC48_RS20385	COG3336	cytochrome c oxidase
FORC48_RS20420	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FORC48_RS20430	COG0772	Belongs to the SEDS family
FORC48_RS20440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FORC48_RS20445	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC48_RS20455	COG4896	Protein conserved in bacteria
FORC48_RS20470	COG1217	gtp-binding protein TYPA
FORC48_RS20480	COG0483	inositol monophosphate 1-phosphatase activity
FORC48_RS20500	COG1982	Orn Lys Arg decarboxylase major
FORC48_RS20550	COG0022	dehydrogenase e1 component
FORC48_RS20555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC48_RS20570	COG0561	phosphatase activity
FORC48_RS20585	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FORC48_RS20590	COG0569	domain protein
FORC48_RS20610	COG0583	DNA-binding transcription factor activity
FORC48_RS20615	COG0517	IMP dehydrogenase activity
FORC48_RS20625	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FORC48_RS20635	COG4703	Protein of unknown function (DUF1797)
FORC48_RS20650	COG2200	EAL domain
FORC48_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS20660	COG1408	metallophosphoesterase
FORC48_RS20705	COG2814	Major facilitator Superfamily
FORC48_RS20725	COG3209	COG3209 Rhs family protein
FORC48_RS20740	COG2205	protein histidine kinase activity
FORC48_RS20750	COG0436	Aminotransferase
FORC48_RS20755	COG1609	Transcriptional regulator
FORC48_RS20760	COG3833	ABC-type maltose transport systems, permease component
FORC48_RS20765	COG1175	transmembrane transport
FORC48_RS20770	COG2182	Extracellular solute-binding protein
FORC48_RS20780	COG0366	Alpha amylase catalytic
FORC48_RS20785	COG3842	ATPase activity
FORC48_RS20825	COG0183	Belongs to the thiolase family
FORC48_RS20860	COG1695	Transcriptional regulator
FORC48_RS20865	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS20885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC48_RS20890	COG0436	Aminotransferase
FORC48_RS20925	COG2084	Dehydrogenase
FORC48_RS20935	COG2199	diguanylate cyclase activity
FORC48_RS20940	COG0778	Nitroreductase
FORC48_RS20965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC48_RS20965	COG2190	(PTS) system
FORC48_RS20965	COG1263	PTS System
FORC48_RS20970	COG3711	transcriptional antiterminator
FORC48_RS20980	COG2188	Transcriptional regulator
FORC48_RS20990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC48_RS21020	COG1547	Domain of unknown function (DUF309)
FORC48_RS21025	COG0456	acetyltransferase
FORC48_RS21030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC48_RS21035	COG4086	secreted protein
FORC48_RS21040	COG0561	phosphatase activity
FORC48_RS21045	COG0697	spore germination
FORC48_RS21060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC48_RS21085	COG0733	neurotransmitter:sodium symporter activity
FORC48_RS21105	COG1686	Belongs to the peptidase S11 family
FORC48_RS21115	COG1725	Transcriptional regulator
FORC48_RS21120	COG1131	(ABC) transporter
FORC48_RS21140	COG1846	Transcriptional regulator
FORC48_RS21155	COG0598	Magnesium transport protein CorA
FORC48_RS21180	COG4974	Belongs to the 'phage' integrase family
FORC48_RS21190	COG0735	belongs to the Fur family
FORC48_RS21195	COG1300	Membrane
FORC48_RS21215	COG0667	Aldo Keto reductase
FORC48_RS21220	COG0656	L-ascorbic acid biosynthetic process
FORC48_RS21225	COG0456	acetyltransferase
FORC48_RS21225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FORC48_RS21235	COG0737	Belongs to the 5'-nucleotidase family
FORC48_RS21235	COG4085	toxin activity
FORC48_RS21235	COG1525	nuclease
FORC48_RS21245	COG0596	Alpha beta hydrolase
FORC48_RS21250	COG2056	Na+-H+ antiporter family
FORC48_RS21255	COG1609	Transcriptional regulator
FORC48_RS21260	COG0456	acetyltransferase
FORC48_RS21265	COG1073	alpha beta
FORC48_RS21280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC48_RS21280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC48_RS21285	COG0307	riboflavin synthase, alpha
FORC48_RS21315	COG1073	alpha beta
FORC48_RS21315	COG2226	methyltransferase
FORC48_RS21330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC48_RS21345	COG1757	Na H antiporter
FORC48_RS21350	COG0737	Belongs to the 5'-nucleotidase family
FORC48_RS21360	COG1522	sequence-specific DNA binding
FORC48_RS21405	COG0300	oxidoreductase activity
FORC48_RS21410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS21415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_RS21420	COG1760	l-serine dehydratase
FORC48_RS21425	COG1760	l-serine dehydratase
FORC48_RS21455	COG1285	pathogenesis
FORC48_RS21465	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC48_RS21470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS21485	COG1376	ErfK ybiS ycfS ynhG family protein
FORC48_RS21490	COG4129	membrane
FORC48_RS21495	COG1126	abc transporter atp-binding protein
FORC48_RS21500	COG0765	amino acid transport
FORC48_RS21505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC48_RS21525	COG2323	membrane
FORC48_RS21530	COG0772	Belongs to the SEDS family
FORC48_RS21540	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC48_RS21545	COG0022	dehydrogenase e1 component
FORC48_RS21550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FORC48_RS21555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC48_RS21570	COG0280	phosphate acetyltransferase
FORC48_RS21580	COG3290	protein histidine kinase activity
FORC48_RS21580	COG3829	transcription factor binding
FORC48_RS21590	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_RS21595	COG3093	addiction module antidote protein HigA
FORC48_RS21615	COG0750	zinc metalloprotease
FORC48_RS21620	COG0497	DNA recombination
FORC48_RS21630	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FORC48_RS21640	COG0142	geranyltranstransferase activity
FORC48_RS21665	COG1302	Protein conserved in bacteria
FORC48_RS21670	COG0439	Biotin carboxylase
FORC48_RS21675	COG0511	ligase activity, forming carbon-carbon bonds
FORC48_RS21720	COG3854	ATPases associated with a variety of cellular activities
FORC48_RS21745	COG0006	proline dipeptidase activity
FORC48_RS21760	COG3872	metal-dependent enzyme
FORC48_RS21770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC48_RS21785	COG1695	Transcriptional regulator
FORC48_RS21805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS21815	COG1609	Transcriptional regulator
FORC48_RS21825	COG2076	Multidrug Resistance protein
FORC48_RS21830	COG2076	Multidrug Resistance protein
FORC48_RS21865	COG1131	(ABC) transporter
FORC48_RS21870	COG1725	Transcriptional regulator
FORC48_RS21905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC48_RS21975	COG1459	type II secretion system
FORC48_RS21980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC48_RS22035	COG0646	methionine synthase
FORC48_RS22035	COG1410	methionine synthase
FORC48_RS22040	COG0646	methionine synthase
FORC48_RS22040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC48_RS22050	COG0626	cystathionine gamma-synthase activity
FORC48_RS22070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS22080	COG1940	carbohydrate kinase activity
FORC48_RS22085	COG4483	Protein conserved in bacteria
FORC48_RS22090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FORC48_RS22095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FORC48_RS22100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC48_RS22105	COG0704	Plays a role in the regulation of phosphate uptake
FORC48_RS22115	COG0573	inorganic phosphate transmembrane transporter activity
FORC48_RS22120	COG0573	inorganic phosphate transmembrane transporter activity
FORC48_RS22125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC48_RS22130	COG0768	penicillin binding
FORC48_RS22135	COG0477	Major facilitator Superfamily
FORC48_RS22140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FORC48_RS22150	COG5521	maltodextrose utilization protein MalA
FORC48_RS22165	COG0735	belongs to the Fur family
FORC48_RS22170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC48_RS22175	COG1121	(ABC) transporter
FORC48_RS22180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS22210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC48_RS22215	COG2384	SAM-dependent methyltransferase
FORC48_RS22225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC48_RS22230	COG0358	DNA primase activity
FORC48_RS22250	COG0517	IMP dehydrogenase activity
FORC48_RS22265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC48_RS22270	COG0295	cytidine deaminase activity
FORC48_RS22275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC48_RS22285	COG1480	7TM receptor with intracellular HD hydrolase
FORC48_RS22290	COG1702	phosphate starvation-inducible protein PhoH
FORC48_RS22310	COG1610	YqeY-like protein
FORC48_RS22315	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC48_RS22325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC48_RS22330	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC48_RS22360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC48_RS22365	COG1733	regulation of RNA biosynthetic process
FORC48_RS22390	COG1466	dna polymerase III delta subunit
FORC48_RS22400	COG0658	competence protein
FORC48_RS22400	COG2333	competence protein COMEC
FORC48_RS22405	COG2131	deaminase
FORC48_RS22410	COG1596	polysaccharide export
FORC48_RS22410	COG1555	photosystem II stabilization
FORC48_RS22415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC48_RS22420	COG2226	methyltransferase
FORC48_RS22425	COG0799	negative regulation of ribosome biogenesis
FORC48_RS22430	COG1713	HD superfamily hydrolase involved in NAD metabolism
FORC48_RS22440	COG1534	Rna-binding protein
FORC48_RS22450	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC48_RS22455	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FORC48_RS22490	COG0778	Nitroreductase
FORC48_RS22495	COG2357	RelA SpoT domain protein
FORC48_RS22505	COG1785	Belongs to the alkaline phosphatase family
FORC48_RS22515	COG2267	carboxylic ester hydrolase activity
FORC48_RS22550	COG1404	Belongs to the peptidase S8 family
FORC48_RS22555	COG3186	Phenylalanine-4-hydroxylase
FORC48_RS22565	COG2514	catechol 2,3-dioxygenase activity
FORC48_RS22570	COG2259	Doxx family
FORC48_RS22610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS22625	COG1454	alcohol dehydrogenase
FORC48_RS22625	COG1012	belongs to the aldehyde dehydrogenase family
FORC48_RS22630	COG0626	cystathionine gamma-synthase activity
FORC48_RS22635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC48_RS22680	COG0826	peptidase U32
FORC48_RS22685	COG0826	peptidase U32
FORC48_RS22690	COG4122	O-methyltransferase activity
FORC48_RS22695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC48_RS22725	COG0628	permease
FORC48_RS22745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC48_RS22760	COG1104	cysteine desulfurase activity
FORC48_RS22765	COG1959	2 iron, 2 sulfur cluster binding
FORC48_RS22770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC48_RS22790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC48_RS22815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC48_RS22825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FORC48_RS22825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC48_RS22830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FORC48_RS22835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC48_RS22835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC48_RS22845	COG2244	polysaccharide biosynthetic process
FORC48_RS22850	COG2323	membrane
FORC48_RS22860	COG1862	Preprotein translocase
FORC48_RS22890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC48_RS22920	COG0157	Belongs to the NadC ModD family
FORC48_RS22925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC48_RS22930	COG1104	cysteine desulfurase activity
FORC48_RS22935	COG1827	regulation of RNA biosynthetic process
FORC48_RS22940	COG2258	MOSC domain
FORC48_RS22945	COG0077	Prephenate dehydratase
FORC48_RS22950	COG0577	efflux transmembrane transporter activity
FORC48_RS22955	COG0577	efflux transmembrane transporter activity
FORC48_RS22960	COG1136	(ABC) transporter
FORC48_RS22965	COG5002	protein histidine kinase activity
FORC48_RS22970	COG0745	RESPONSE REGULATOR receiver
FORC48_RS22980	COG3290	protein histidine kinase activity
FORC48_RS22990	COG2868	ribosomal protein
FORC48_RS23000	COG1530	ribonuclease E activity
FORC48_RS23005	COG1994	Peptidase M50
FORC48_RS23010	COG0739	heme binding
FORC48_RS23015	COG2894	cell division
FORC48_RS23035	COG1077	Cell shape determining protein MreB Mrl
FORC48_RS23055	COG0285	dihydrofolate synthase activity
FORC48_RS23070	COG1388	LysM domain
FORC48_RS23080	COG0113	porphobilinogen synthase activity
FORC48_RS23085	COG1587	Uroporphyrinogen-III synthase
FORC48_RS23095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC48_RS23105	COG1846	Transcriptional regulator
FORC48_RS23110	COG1764	response to oxidative stress
FORC48_RS23125	COG0470	DNA polymerase III
FORC48_RS23125	COG1067	ATP-dependent peptidase activity
FORC48_RS23180	COG0622	Phosphoesterase
FORC48_RS23195	COG5401	PFAM Sporulation and spore germination
FORC48_RS23215	COG1309	transcriptional regulator
FORC48_RS23225	COG2197	response regulator
FORC48_RS23230	COG2233	PERMEase
FORC48_RS23235	COG0402	S-adenosylhomocysteine deaminase activity
FORC48_RS23240	COG1983	PspC domain protein
FORC48_RS23245	COG1396	sequence-specific DNA binding
FORC48_RS23250	COG0697	spore germination
FORC48_RS23260	COG1959	2 iron, 2 sulfur cluster binding
FORC48_RS23265	COG1668	transmembrane transport
FORC48_RS23270	COG4152	abc transporter atp-binding protein
FORC48_RS23275	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FORC48_RS23280	COG1360	Flagellar Motor Protein
FORC48_RS23285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC48_RS23295	COG1876	peptidase activity
FORC48_RS23300	COG0824	Thioesterase
FORC48_RS23305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC48_RS23310	COG1053	succinate dehydrogenase
FORC48_RS23315	COG2009	succinate dehydrogenase
FORC48_RS23320	COG1719	4-vinyl reductase, 4VR
FORC48_RS23330	COG3118	belongs to the thioredoxin family
FORC48_RS23335	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FORC48_RS23340	COG2086	electron transfer activity
FORC48_RS23345	COG1024	Enoyl-CoA hydratase
FORC48_RS23350	COG1309	transcriptional regulator
FORC48_RS23355	COG0318	PFAM AMP-dependent synthetase and ligase
FORC48_RS23385	COG2318	DinB family
FORC48_RS23415	COG1131	(ABC) transporter
FORC48_RS23420	COG2205	protein histidine kinase activity
FORC48_RS23425	COG0745	RESPONSE REGULATOR receiver
FORC48_RS23435	COG4895	conserved protein (DUF2196)
FORC48_RS23440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC48_RS23450	COG4509	Sortase family
FORC48_RS23455	COG1120	ATPase activity
FORC48_RS23470	COG5386	Cell surface protein
FORC48_RS23480	COG5386	Cell surface protein
FORC48_RS23485	COG1114	Component of the transport system for branched-chain amino acids
FORC48_RS23490	COG1187	pseudouridine synthase activity
FORC48_RS23505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC48_RS23505	COG1796	DNA polymerase
FORC48_RS23510	COG1286	toxin biosynthetic process
FORC48_RS23555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC48_RS23565	COG1418	mRNA catabolic process
FORC48_RS23585	COG2814	Major facilitator Superfamily
FORC48_RS23590	COG1566	PFAM secretion protein HlyD family protein
FORC48_RS23595	COG1309	transcriptional regulator
FORC48_RS23600	COG1363	Peptidase, m42
FORC48_RS23625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC48_RS23640	COG1484	DNA-dependent DNA replication
FORC48_RS23645	COG3611	Membrane attachment protein
FORC48_RS23655	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FORC48_RS23665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC48_RS23675	COG1971	Probably functions as a manganese efflux pump
FORC48_RS23685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC48_RS23685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC48_RS23690	COG5002	protein histidine kinase activity
FORC48_RS23695	COG0745	RESPONSE REGULATOR receiver
FORC48_RS23720	COG0538	isocitrate dehydrogenase activity
FORC48_RS23725	COG0372	Belongs to the citrate synthase family
FORC48_RS23740	COG0628	permease
FORC48_RS23745	COG3030	protein affecting phage T7 exclusion by the F plasmid
FORC48_RS23770	COG1725	Transcriptional regulator
FORC48_RS23775	COG0281	malic enzyme
FORC48_RS23780	COG0587	DNA-directed DNA polymerase activity
FORC48_RS23795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FORC48_RS23810	COG4109	DRTGG domain
FORC48_RS23825	COG0006	proline dipeptidase activity
FORC48_RS23860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS23865	COG0662	Cupin 2, conserved barrel domain protein
FORC48_RS23880	COG1028	Short-chain dehydrogenase reductase Sdr
FORC48_RS23885	COG0589	response to stress
FORC48_RS23930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS23955	COG0827	DNA restriction-modification system
FORC48_RS23960	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FORC48_RS23965	COG3874	Sporulation protein YtfJ
FORC48_RS23980	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FORC48_RS23990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC48_RS24005	COG1104	cysteine desulfurase activity
FORC48_RS24015	COG0583	DNA-binding transcription factor activity
FORC48_RS24020	COG0697	spore germination
FORC48_RS24025	COG1309	transcriptional regulator
FORC48_RS24030	COG1956	GAF domain-containing protein
FORC48_RS24035	COG0626	cystathionine gamma-synthase activity
FORC48_RS24090	COG0110	maltose O-acetyltransferase activity
FORC48_RS24095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC48_RS24100	COG0454	-acetyltransferase
FORC48_RS24105	COG0517	IMP dehydrogenase activity
FORC48_RS24110	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC48_RS24125	COG0745	RESPONSE REGULATOR receiver
FORC48_RS24130	COG5002	protein histidine kinase activity
FORC48_RS24135	COG0666	response to abiotic stimulus
FORC48_RS24170	COG1609	Transcriptional regulator
FORC48_RS24185	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FORC48_RS24185	COG1605	Chorismate mutase
FORC48_RS24190	COG4851	CamS sex pheromone cAM373 precursor
FORC48_RS24195	COG3118	belongs to the thioredoxin family
FORC48_RS24205	COG2309	aminopeptidase activity
FORC48_RS24220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS24235	COG1674	ftsk spoiiie
FORC48_RS24240	COG1388	LysM domain
FORC48_RS24240	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC48_RS24250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC48_RS24260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_RS24265	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC48_RS24270	COG1363	Peptidase, m42
FORC48_RS24280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS24295	COG0510	thiamine kinase activity
FORC48_RS24300	COG1523	belongs to the glycosyl hydrolase 13 family
FORC48_RS24315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC48_RS24320	COG1349	DNA-binding transcription factor activity
FORC48_RS24325	COG1187	pseudouridine synthase activity
FORC48_RS24330	COG2244	polysaccharide biosynthetic process
FORC48_RS24335	COG2081	HI0933 family
FORC48_RS24345	COG2814	Major facilitator Superfamily
FORC48_RS24355	COG3832	glyoxalase III activity
FORC48_RS24380	COG1329	Transcriptional regulator
FORC48_RS24405	COG0314	molybdopterin synthase activity
FORC48_RS24410	COG1763	Mo-molybdopterin cofactor biosynthetic process
FORC48_RS24415	COG0303	'Molybdopterin
FORC48_RS24425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC48_RS24430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FORC48_RS24455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC48_RS24465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FORC48_RS24505	COG2814	Major facilitator Superfamily
FORC48_RS24510	COG0475	glutathione-regulated potassium exporter activity
FORC48_RS24515	COG0490	domain, Protein
FORC48_RS24520	COG0582	viral genome integration into host DNA
FORC48_RS24530	COG1136	(ABC) transporter
FORC48_RS24550	COG1242	4 iron, 4 sulfur cluster binding
FORC48_RS24555	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FORC48_RS24560	COG1794	racemase activity, acting on amino acids and derivatives
FORC48_RS24575	COG2267	carboxylic ester hydrolase activity
FORC48_RS24580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC48_RS24585	COG0671	phosphoesterase, PA-phosphatase related
FORC48_RS24590	COG0438	transferase activity, transferring glycosyl groups
FORC48_RS24615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS24665	COG5002	protein histidine kinase activity
FORC48_RS24670	COG3852	Histidine kinase
FORC48_RS24675	COG0753	catalase activity
FORC48_RS24685	COG2267	carboxylic ester hydrolase activity
FORC48_RS24710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC48_RS24715	COG1116	anion transmembrane transporter activity
FORC48_RS24720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC48_RS24745	COG0494	nUDIX hydrolase
FORC48_RS24780	COG1854	S-ribosylhomocysteine lyase activity
FORC48_RS24790	COG0288	reversible hydration of carbon dioxide
FORC48_RS24795	COG1271	oxidase subunit
FORC48_RS24800	COG1294	oxidase, subunit
FORC48_RS24815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS24840	COG1842	Phage shock protein A
FORC48_RS24870	COG5002	protein histidine kinase activity
FORC48_RS24875	COG0745	RESPONSE REGULATOR receiver
FORC48_RS24900	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FORC48_RS24905	COG1597	lipid kinase activity
FORC48_RS24950	COG0586	Pfam SNARE associated Golgi protein
FORC48_RS24960	COG0577	efflux transmembrane transporter activity
FORC48_RS24965	COG1136	(ABC) transporter
FORC48_RS24970	COG3708	Transcriptional regulator
FORC48_RS24970	COG2207	Transcriptional regulator
FORC48_RS24990	COG5658	integral membrane protein
FORC48_RS24995	COG0640	Transcriptional regulator
FORC48_RS25000	COG0745	RESPONSE REGULATOR receiver
FORC48_RS25005	COG2205	protein histidine kinase activity
FORC48_RS25010	COG0577	efflux transmembrane transporter activity
FORC48_RS25015	COG0577	efflux transmembrane transporter activity
FORC48_RS25020	COG1136	(ABC) transporter
FORC48_RS25025	COG0577	efflux transmembrane transporter activity
FORC48_RS25050	COG2188	Transcriptional regulator
FORC48_RS25070	COG3964	amidohydrolase
FORC48_RS25090	COG4948	Mandelate Racemase Muconate Lactonizing
FORC48_RS25105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC48_RS25110	COG0596	Alpha beta hydrolase
FORC48_RS25120	COG1169	isochorismate synthase
FORC48_RS25125	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC48_RS25130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC48_RS25160	COG0058	SHG alpha-glucan phosphorylase activity
FORC48_RS25170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC48_RS25190	COG1404	Belongs to the peptidase S8 family
FORC48_RS25295	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC48_RS25335	COG1285	pathogenesis
FORC48_RS25340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC48_RS25360	COG2155	Conserved Protein
FORC48_RS25365	COG1098	S1 RNA binding domain
FORC48_RS25370	COG0436	Aminotransferase
FORC48_RS25375	COG1522	sequence-specific DNA binding
FORC48_RS25380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC48_RS25385	COG2267	carboxylic ester hydrolase activity
FORC48_RS25395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FORC48_RS25415	COG5018	Exonuclease
FORC48_RS25420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC48_RS25445	COG2050	protein possibly involved in aromatic compounds catabolism
FORC48_RS25455	COG1268	BioY protein
FORC48_RS25465	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC48_RS25470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC48_RS25490	COG2076	Multidrug Resistance protein
FORC48_RS25495	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC48_RS25505	COG3584	3D domain protein
FORC48_RS25520	COG1252	NADH dehydrogenase
FORC48_RS25535	COG3708	Transcriptional regulator
FORC48_RS25550	COG1683	Conserved Protein
FORC48_RS25570	COG0316	Belongs to the HesB IscA family
FORC48_RS25585	COG1252	NADH dehydrogenase
FORC48_RS25595	COG2274	protein secretion by the type I secretion system
FORC48_RS25600	COG0390	transport system, permease component
FORC48_RS25605	COG2824	Alkylphosphonate utilization operon protein PhnA
FORC48_RS25630	COG4837	Protein of unknown function (DUF1462)
FORC48_RS25635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC48_RS25645	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC48_RS25650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC48_RS25670	COG1358	cellular component organization or biogenesis
FORC48_RS25680	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC48_RS25685	COG0647	UMP catabolic process
FORC48_RS25695	COG2445	Protein of unknown function DUF86
FORC48_RS25700	COG1494	fructose-1,6-bisphosphatase
FORC48_RS25725	COG4470	Protein conserved in bacteria
FORC48_RS25735	COG0789	Transcriptional regulator
FORC48_RS25740	COG4377	Putative membrane peptidase family (DUF2324)
FORC48_RS25765	COG0739	heme binding
FORC48_RS25775	COG3377	Domain of unknown function (DUF1805)
FORC48_RS25780	COG0737	Belongs to the 5'-nucleotidase family
FORC48_RS25785	COG0719	Fe-S assembly protein
FORC48_RS25790	COG0822	iron-sulfur transferase activity
FORC48_RS25795	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC48_RS25800	COG0719	Fe-S assembly protein
FORC48_RS25805	COG0396	ATPase activity
FORC48_RS25810	COG1464	Belongs to the NlpA lipoprotein family
FORC48_RS25815	COG1464	Belongs to the NlpA lipoprotein family
FORC48_RS25820	COG2011	ABC-type metal ion transport system permease component
FORC48_RS25840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC48_RS25845	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FORC48_RS25855	COG1393	Belongs to the ArsC family
FORC48_RS25895	COG1309	transcriptional regulator
FORC48_RS25900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC48_RS25905	COG1960	acyl-CoA dehydrogenase activity
FORC48_RS25915	COG0183	Belongs to the thiolase family
FORC48_RS25920	COG1024	Enoyl-CoA hydratase
FORC48_RS25920	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC48_RS25935	COG1686	Belongs to the peptidase S11 family
FORC48_RS25950	COG0011	TIGRFAM Protein of
FORC48_RS25955	COG0840	transmembrane signaling receptor activity
FORC48_RS25970	COG2814	Major facilitator Superfamily
FORC48_RS25975	COG0531	amino acid
FORC48_RS26000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FORC48_RS26040	COG0586	Pfam SNARE associated Golgi protein
FORC48_RS26050	COG1376	ErfK ybiS ycfS ynhG family protein
FORC48_RS26055	COG0745	RESPONSE REGULATOR receiver
FORC48_RS26060	COG5002	protein histidine kinase activity
FORC48_RS26090	COG0840	transmembrane signaling receptor activity
FORC48_RS26095	COG2151	metal-sulfur cluster biosynthetic enzyme
FORC48_RS26100	COG3227	Zinc metalloprotease (Elastase)
FORC48_RS26105	COG1741	Belongs to the pirin family
FORC48_RS26120	COG0475	glutathione-regulated potassium exporter activity
FORC48_RS26125	COG0490	domain, Protein
FORC48_RS26135	COG1115	amino acid carrier protein
FORC48_RS26140	COG0783	Belongs to the Dps family
FORC48_RS26155	COG1611	Belongs to the LOG family
FORC48_RS26165	COG1528	Iron-storage protein
FORC48_RS26175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS26180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS26185	COG1115	amino acid carrier protein
FORC48_RS26190	COG1115	amino acid carrier protein
FORC48_RS26195	COG2910	NAD(P)H-binding
FORC48_RS26215	COG0656	L-ascorbic acid biosynthetic process
FORC48_RS26220	COG2814	Major facilitator Superfamily
FORC48_RS26225	COG1733	regulation of RNA biosynthetic process
FORC48_RS26235	COG1252	NADH dehydrogenase
FORC48_RS26290	COG0488	(ABC) transporter
FORC48_RS26295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC48_RS26370	COG0557	exoribonuclease II activity
FORC48_RS26375	COG1647	Serine aminopeptidase, S33
FORC48_RS26380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC48_RS26385	COG1346	cytolysis
FORC48_RS26420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC48_RS26435	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FORC48_RS26440	COG1668	transmembrane transport
FORC48_RS26445	COG4152	abc transporter atp-binding protein
FORC48_RS26450	COG4585	Histidine kinase
FORC48_RS26480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC48_RS26495	COG2323	membrane
FORC48_RS26510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC48_RS26520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC48_RS26530	COG1051	belongs to the nudix hydrolase family
FORC48_RS26540	COG0492	ferredoxin-NADP+ reductase activity
FORC48_RS26545	COG0457	Tetratricopeptide repeat
FORC48_RS26550	COG0110	maltose O-acetyltransferase activity
FORC48_RS26570	COG1950	PFAM Membrane protein of
FORC48_RS26580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC48_RS26585	COG0556	nucleotide-excision repair
FORC48_RS26600	COG0789	Transcriptional regulator
FORC48_RS26620	COG0583	DNA-binding transcription factor activity
FORC48_RS26630	COG0655	NAD(P)H dehydrogenase (quinone) activity
FORC48_RS26635	COG0488	(ABC) transporter
FORC48_RS26645	COG1132	(ABC) transporter
FORC48_RS26655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC48_RS26660	COG3409	Peptidoglycan-binding domain 1 protein
FORC48_RS26660	COG0793	Belongs to the peptidase S41A family
FORC48_RS26665	COG2177	Part of the ABC transporter FtsEX involved in
FORC48_RS26670	COG2884	Cell division ATP-binding protein ftsE
FORC48_RS26690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FORC48_RS26705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC48_RS26710	COG1278	Cold shock
FORC48_RS26715	COG1040	competence protein
FORC48_RS26720	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FORC48_RS26725	COG0791	NLP P60 protein
FORC48_RS26725	COG1388	LysM domain
FORC48_RS26730	COG1733	regulation of RNA biosynthetic process
FORC48_RS26740	COG1307	EDD domain protein, DegV family
FORC48_RS26745	COG1739	Uncharacterized protein family UPF0029
FORC48_RS26750	COG1316	TRANSCRIPTIONal
FORC48_RS26755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC48_RS26760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC48_RS26765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC48_RS26775	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FORC48_RS26775	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC48_RS26795	COG1486	melibiose metabolic process
FORC48_RS26800	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC48_RS26805	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC48_RS26825	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC48_RS26835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC48_RS26840	COG1301	dicarboxylic acid transport
FORC48_RS26855	COG1511	domain protein
FORC48_RS26860	COG0583	DNA-binding transcription factor activity
FORC48_RS26865	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC48_RS26875	COG1271	oxidase subunit
FORC48_RS26880	COG1294	oxidase, subunit
FORC48_RS26885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FORC48_RS26920	COG1620	l-lactate permease
FORC48_RS26930	COG2389	metal-binding protein
FORC48_RS26945	COG1368	sulfuric ester hydrolase activity
FORC48_RS26960	COG0791	NLP P60 protein
FORC48_RS26960	COG1388	LysM domain
FORC48_RS26965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC48_RS26975	COG1215	transferase activity, transferring glycosyl groups
FORC48_RS26985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC48_RS26995	COG1388	LysM domain
FORC48_RS26995	COG3584	3D domain protein
FORC48_RS27020	COG4715	Zinc finger, swim domain protein
FORC48_RS27025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC48_RS27065	COG0577	efflux transmembrane transporter activity
FORC48_RS27070	COG1136	(ABC) transporter
FORC48_RS27090	COG2271	Major facilitator Superfamily
FORC48_RS27105	COG5002	protein histidine kinase activity
FORC48_RS27110	COG0745	RESPONSE REGULATOR receiver
FORC48_RS27120	COG1316	TRANSCRIPTIONal
FORC48_RS27130	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FORC48_RS27160	COG0438	transferase activity, transferring glycosyl groups
FORC48_RS27175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC48_RS27185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC48_RS27190	COG1086	Polysaccharide biosynthesis protein
FORC48_RS27195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FORC48_RS27200	COG4464	protein tyrosine phosphatase activity
FORC48_RS27205	COG0489	protein tyrosine kinase activity
FORC48_RS27210	COG3944	biosynthesis protein
FORC48_RS27215	COG0489	protein tyrosine kinase activity
FORC48_RS27230	COG1609	Transcriptional regulator
FORC48_RS27240	COG0739	heme binding
FORC48_RS27255	COG3279	Response regulator of the LytR AlgR family
FORC48_RS27260	COG2385	sporulation resulting in formation of a cellular spore
FORC48_RS27275	COG4836	Membrane
FORC48_RS27280	COG1007	ATP synthesis coupled electron transport
FORC48_RS27285	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC48_RS27290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FORC48_RS27300	COG0839	Belongs to the complex I subunit 6 family
FORC48_RS27320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FORC48_RS27335	COG5001	Diguanylate cyclase
FORC48_RS27335	COG3300	MHYT domain
FORC48_RS27390	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC48_RS27425	COG0698	ribose 5-phosphate isomerase
FORC48_RS27445	COG2259	Doxx family
FORC48_RS27450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FORC48_RS27470	COG0009	L-threonylcarbamoyladenylate synthase
FORC48_RS27505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC48_RS27510	COG1494	fructose-1,6-bisphosphatase
FORC48_RS27535	COG4821	SIS domain
FORC48_RS27545	COG3343	RNA polymerase activity
FORC48_RS27555	COG1960	acyl-CoA dehydrogenase activity
FORC48_RS27560	COG1960	acyl-CoA dehydrogenase activity
FORC48_RS27565	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC48_RS27570	COG0183	Belongs to the thiolase family
FORC48_RS27575	COG0247	lactate metabolic process
FORC48_RS27575	COG2181	nitrate reductase activity
FORC48_RS27580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC48_RS27590	COG5001	Diguanylate cyclase
FORC48_RS27590	COG3300	MHYT domain
FORC48_RS27605	COG3227	Zinc metalloprotease (Elastase)
FORC48_RS27610	COG2197	response regulator
FORC48_RS27615	COG4585	Histidine kinase
FORC48_RS27620	COG0842	Transport permease protein
FORC48_RS27625	COG1131	(ABC) transporter
FORC48_RS27630	COG0024	Methionine aminopeptidase
FORC48_RS27640	COG2234	aminopeptidase activity
FORC48_RS27660	COG1595	DNA-templated transcription, initiation
FORC48_RS27675	COG4506	Protein conserved in bacteria
FORC48_RS27680	COG1619	proteins homologs of microcin C7 resistance protein MccF
FORC48_RS27720	COG2814	Major facilitator Superfamily
FORC48_RS27725	COG0789	Transcriptional regulator
FORC48_RS27730	COG0584	glycerophosphoryl diester phosphodiesterase
FORC48_RS27735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC48_RS27745	COG1994	Peptidase M50
FORC48_RS27755	COG1078	dGTPase activity
FORC48_RS27760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC48_RS27765	COG1120	ATPase activity
FORC48_RS27770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS27775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC48_RS27795	COG0280	phosphate acetyltransferase
FORC48_RS27810	COG3773	Cell wall hydrolase
FORC48_RS27820	COG2363	Small membrane protein
FORC48_RS27830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC48_RS27835	COG2233	PERMEase
FORC48_RS27840	COG0561	phosphatase activity
FORC48_RS27845	COG2814	Major facilitator Superfamily
FORC48_RS27855	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FORC48_RS27860	COG1131	(ABC) transporter
FORC48_RS27865	COG2755	lipolytic protein G-D-S-L family
FORC48_RS27870	COG1609	Transcriptional regulator
FORC48_RS27880	COG0460	homoserine dehydrogenase
FORC48_RS27890	COG2873	o-acetylhomoserine
FORC48_RS27900	COG1011	Hydrolase
FORC48_RS27905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC48_RS27915	COG2197	response regulator
FORC48_RS27920	COG2203	Gaf domain
FORC48_RS27920	COG4585	Histidine kinase
FORC48_RS27925	COG0351	phosphomethylpyrimidine kinase
FORC48_RS27930	COG3706	GGDEF domain
FORC48_RS27935	COG2879	small protein
FORC48_RS27940	COG1966	Carbon starvation protein
FORC48_RS27945	COG3279	Response regulator of the LytR AlgR family
FORC48_RS27950	COG0477	Major facilitator Superfamily
FORC48_RS27960	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FORC48_RS27965	COG0438	transferase activity, transferring glycosyl groups
FORC48_RS27980	COG0840	transmembrane signaling receptor activity
FORC48_RS27990	COG1607	acyl-coa hydrolase
FORC48_RS27995	COG1216	Glycosyl transferase, family 2
FORC48_RS28005	COG1216	Glycosyl transferase, family 2
FORC48_RS28015	COG4485	Bacterial membrane protein, YfhO
FORC48_RS28020	COG0463	Glycosyl transferase, family 2
FORC48_RS28025	COG0488	(ABC) transporter
FORC48_RS28030	COG1309	transcriptional regulator
FORC48_RS28035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC48_RS28040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC48_RS28040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC48_RS28045	COG0628	permease
FORC48_RS28065	COG3275	phosphorelay sensor kinase activity
FORC48_RS28070	COG2814	Major facilitator Superfamily
FORC48_RS28075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC48_RS28080	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FORC48_RS28110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC48_RS28135	COG1164	Oligoendopeptidase f
FORC48_RS28145	COG5002	protein histidine kinase activity
FORC48_RS28160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC48_RS28165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FORC48_RS28170	COG4853	Protein conserved in bacteria
FORC48_RS28180	COG5002	protein histidine kinase activity
FORC48_RS28185	COG0745	RESPONSE REGULATOR receiver
FORC48_RS28215	COG0305	Participates in initiation and elongation during chromosome replication
FORC48_RS28225	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FORC48_RS28250	COG0012	GTP binding
FORC48_RS28255	COG4481	Protein conserved in bacteria
FORC48_RS28260	COG0668	transmembrane transport
FORC48_RS28270	COG1475	DNA binding
FORC48_RS28275	COG1192	Involved in chromosome partitioning
FORC48_RS28300	COG1847	R3H domain protein
FORC48_RS28315	COG0230	Belongs to the bacterial ribosomal protein bL34 family