locus-tag	class	description
F3L01_RS00010	COG0592	DNA-directed DNA polymerase activity
F3L01_RS00015	COG2501	S4 domain
F3L01_RS00025	COG0187	DNA topoisomerase II activity
F3L01_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3L01_RS00065	COG0517	IMP dehydrogenase activity
F3L01_RS00065	COG0516	GMP reductase activity
F3L01_RS00070	COG1686	Belongs to the peptidase S11 family
F3L01_RS00100	COG1428	Deoxynucleoside kinase
F3L01_RS00105	COG1428	Deoxynucleoside kinase
F3L01_RS00110	COG1335	isochorismatase
F3L01_RS00115	COG0590	tRNA wobble adenosine to inosine editing
F3L01_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3L01_RS00180	COG1982	Orn Lys Arg decarboxylase major
F3L01_RS00190	COG0470	DNA polymerase III
F3L01_RS00195	COG1774	PSP1 C-terminal conserved region
F3L01_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F3L01_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3L01_RS00220	COG2002	toxin-antitoxin pair type II binding
F3L01_RS00230	COG0084	hydrolase, TatD family'
F3L01_RS00250	COG4466	Protein conserved in bacteria
F3L01_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3L01_RS00270	COG0251	oxidation-reduction process
F3L01_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3L01_RS00305	COG2002	toxin-antitoxin pair type II binding
F3L01_RS00310	COG2244	polysaccharide biosynthetic process
F3L01_RS00315	COG3956	TIGRFAM MazG family protein
F3L01_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F3L01_RS00340	COG1098	S1 RNA binding domain
F3L01_RS00355	COG2208	phosphoserine phosphatase activity
F3L01_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3L01_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3L01_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3L01_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
F3L01_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3L01_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3L01_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3L01_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3L01_RS00420	COG1396	sequence-specific DNA binding
F3L01_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3L01_RS00515	COG3880	PFAM UvrB UvrC protein
F3L01_RS00525	COG0542	response to heat
F3L01_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F3L01_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
F3L01_RS00560	COG1045	serine acetyltransferase
F3L01_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3L01_RS00580	COG3688	RNA-binding protein containing a PIN domain
F3L01_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3L01_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
F3L01_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F3L01_RS00625	COG2813	Specifically methylates the guanine in position
F3L01_RS00640	COG1358	cellular component organization or biogenesis
F3L01_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F3L01_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
F3L01_RS00770	COG0201	protein transport
F3L01_RS00780	COG0024	Methionine aminopeptidase
F3L01_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F3L01_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3L01_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS00855	COG0489	protein tyrosine kinase activity
F3L01_RS00865	COG2194	sulfuric ester hydrolase activity
F3L01_RS00870	COG0726	polysaccharide deacetylase
F3L01_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
F3L01_RS00955	COG4856	YbbR-like protein
F3L01_RS00995	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS01000	COG2011	ABC-type metal ion transport system permease component
F3L01_RS01010	COG1464	Belongs to the NlpA lipoprotein family
F3L01_RS01015	COG0604	alcohol dehydrogenase
F3L01_RS01025	COG0277	FAD linked oxidase domain protein
F3L01_RS01030	COG2271	Major facilitator Superfamily
F3L01_RS01040	COG2814	Major facilitator Superfamily
F3L01_RS01060	COG0601	transmembrane transport
F3L01_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3L01_RS01070	COG0444	Belongs to the ABC transporter superfamily
F3L01_RS01075	COG4608	Belongs to the ABC transporter superfamily
F3L01_RS01080	COG4166	transmembrane transport
F3L01_RS01090	COG2207	Transcriptional regulator
F3L01_RS01105	COG4166	transmembrane transport
F3L01_RS01110	COG4166	transmembrane transport
F3L01_RS01115	COG0656	L-ascorbic acid biosynthetic process
F3L01_RS01130	COG4149	molybdate abc transporter
F3L01_RS01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3L01_RS01140	COG1910	domain protein
F3L01_RS01155	COG0697	spore germination
F3L01_RS01170	COG0204	Acyl-transferase
F3L01_RS01180	COG1609	Transcriptional regulator
F3L01_RS01190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS01225	COG0488	(ABC) transporter
F3L01_RS01235	COG0747	negative chemotaxis
F3L01_RS01240	COG0601	transmembrane transport
F3L01_RS01250	COG0444	Belongs to the ABC transporter superfamily
F3L01_RS01255	COG4608	Belongs to the ABC transporter superfamily
F3L01_RS01260	COG0561	phosphatase activity
F3L01_RS01285	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F3L01_RS01290	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3L01_RS01300	COG0531	amino acid
F3L01_RS01305	COG2814	Major facilitator Superfamily
F3L01_RS01315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3L01_RS01325	COG4294	response to UV
F3L01_RS01330	COG0705	Rhomboid family
F3L01_RS01340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3L01_RS01345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3L01_RS01350	COG0864	Transcriptional regulator
F3L01_RS01355	COG2337	Toxic component of a toxin-antitoxin (TA) module
F3L01_RS01360	COG2183	response to ionizing radiation
F3L01_RS01460	COG0802	atpase or kinase
F3L01_RS01465	COG1214	PFAM Peptidase M22, glycoprotease
F3L01_RS01470	COG0456	acetyltransferase
F3L01_RS01480	COG0488	(ABC) transporter
F3L01_RS01495	COG1266	CAAX protease self-immunity
F3L01_RS01515	COG2252	PERMEase
F3L01_RS01525	COG5002	protein histidine kinase activity
F3L01_RS01550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F3L01_RS01590	COG2205	protein histidine kinase activity
F3L01_RS01595	COG0745	RESPONSE REGULATOR receiver
F3L01_RS01625	COG2226	methyltransferase
F3L01_RS01635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3L01_RS01645	COG1215	transferase activity, transferring glycosyl groups
F3L01_RS01665	COG0697	spore germination
F3L01_RS01690	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3L01_RS01695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3L01_RS01700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3L01_RS01710	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3L01_RS01725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3L01_RS01735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3L01_RS01745	COG0151	Belongs to the GarS family
F3L01_RS01770	COG0210	DNA helicase
F3L01_RS01780	COG4851	CamS sex pheromone cAM373 precursor
F3L01_RS01795	COG1335	isochorismatase
F3L01_RS01805	COG2011	ABC-type metal ion transport system permease component
F3L01_RS01810	COG1464	Belongs to the NlpA lipoprotein family
F3L01_RS01825	COG0003	Pfam Anion-transporting ATPase
F3L01_RS01830	COG1846	Transcriptional regulator
F3L01_RS01835	COG4682	membrane
F3L01_RS01855	COG1597	lipid kinase activity
F3L01_RS01865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3L01_RS01875	COG1012	belongs to the aldehyde dehydrogenase family
F3L01_RS01880	COG2076	Multidrug Resistance protein
F3L01_RS01890	COG2309	aminopeptidase activity
F3L01_RS01910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS01920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3L01_RS01925	COG4807	Protein conserved in bacteria
F3L01_RS01955	COG1473	amidohydrolase
F3L01_RS01970	COG0450	alkyl hydroperoxide reductase
F3L01_RS01990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS01995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS02000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS02005	COG0492	ferredoxin-NADP+ reductase activity
F3L01_RS02015	COG0166	Belongs to the GPI family
F3L01_RS02040	COG5002	protein histidine kinase activity
F3L01_RS02060	COG3541	Predicted nucleotidyltransferase
F3L01_RS02065	COG2814	Major facilitator Superfamily
F3L01_RS02070	COG0723	plastoquinol--plastocyanin reductase activity
F3L01_RS02070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3L01_RS02080	COG0765	amino acid transport
F3L01_RS02085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3L01_RS02090	COG1126	abc transporter atp-binding protein
F3L01_RS02095	COG0840	transmembrane signaling receptor activity
F3L01_RS02120	COG0549	Belongs to the carbamate kinase family
F3L01_RS02125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3L01_RS02135	COG0277	FAD linked oxidase domain protein
F3L01_RS02140	COG0366	Alpha amylase catalytic
F3L01_RS02145	COG1263	PTS System
F3L01_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3L01_RS02145	COG2190	(PTS) system
F3L01_RS02175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F3L01_RS02195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3L01_RS02200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3L01_RS02205	COG1116	anion transmembrane transporter activity
F3L01_RS02255	COG2270	Major facilitator Superfamily
F3L01_RS02285	COG2310	stress, protein
F3L01_RS02290	COG2310	stress, protein
F3L01_RS02295	COG2310	stress, protein
F3L01_RS02300	COG0861	Integral membrane protein TerC family
F3L01_RS02310	COG3853	Toxic anion resistance protein (TelA)
F3L01_RS02325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3L01_RS02335	COG1295	ribonuclease BN
F3L01_RS02340	COG2217	Heavy metal translocating P-type atpase
F3L01_RS02345	COG0697	spore germination
F3L01_RS02365	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS02380	COG3871	stress protein (general stress protein 26)
F3L01_RS02385	COG0387	Pfam Sodium calcium exchanger
F3L01_RS02395	COG0535	radical SAM domain protein
F3L01_RS02415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F3L01_RS02420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3L01_RS02435	COG3829	transcription factor binding
F3L01_RS02445	COG0833	amino acid
F3L01_RS02450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3L01_RS02480	COG1263	PTS System
F3L01_RS02480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3L01_RS02485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3L01_RS02500	COG0463	Glycosyl transferase, family 2
F3L01_RS02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3L01_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3L01_RS02530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3L01_RS02550	COG1228	amidohydrolase
F3L01_RS02555	COG1090	epimerase
F3L01_RS02585	COG1988	membrane-bound metal-dependent
F3L01_RS02590	COG1194	a g-specific adenine glycosylase
F3L01_RS02615	COG1132	(ABC) transporter
F3L01_RS02620	COG4129	membrane
F3L01_RS02625	COG0067	glutamate synthase
F3L01_RS02625	COG0069	glutamate synthase activity
F3L01_RS02625	COG0070	glutamate synthase
F3L01_RS02635	COG4555	ABC transporter
F3L01_RS02655	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3L01_RS02660	COG0735	belongs to the Fur family
F3L01_RS02780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3L01_RS02805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3L01_RS02815	COG2766	serine protein kinase
F3L01_RS02835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3L01_RS02845	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3L01_RS02850	COG2268	Band 7 protein
F3L01_RS02860	COG3290	protein histidine kinase activity
F3L01_RS02865	COG4565	transcriptional regulatory protein
F3L01_RS02870	COG2851	Citrate transporter
F3L01_RS02895	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
F3L01_RS02900	COG3842	ATPase activity
F3L01_RS02905	COG1175	transmembrane transport
F3L01_RS02910	COG0395	ABC-type sugar transport system, permease component
F3L01_RS02920	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3L01_RS02925	COG0745	RESPONSE REGULATOR receiver
F3L01_RS02930	COG3850	Histidine kinase
F3L01_RS02930	COG5002	protein histidine kinase activity
F3L01_RS02940	COG4990	cell redox homeostasis
F3L01_RS02950	COG3290	protein histidine kinase activity
F3L01_RS02955	COG4565	transcriptional regulatory protein
F3L01_RS02960	COG3493	citrate carrier protein
F3L01_RS02965	COG0281	malic enzyme
F3L01_RS02975	COG0697	spore germination
F3L01_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS02990	COG5002	protein histidine kinase activity
F3L01_RS03005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3L01_RS03010	COG3383	formate dehydrogenase (NAD+) activity
F3L01_RS03015	COG2427	Protein of unknown function (DUF1641)
F3L01_RS03040	COG0640	Transcriptional regulator
F3L01_RS03045	COG2217	Heavy metal translocating P-type atpase
F3L01_RS03065	COG3227	Zinc metalloprotease (Elastase)
F3L01_RS03085	COG2720	vancomycin resistance protein
F3L01_RS03090	COG1316	TRANSCRIPTIONal
F3L01_RS03095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS03100	COG0346	lactoylglutathione lyase activity
F3L01_RS03105	COG1253	flavin adenine dinucleotide binding
F3L01_RS03110	COG1027	Aspartate ammonia-lyase
F3L01_RS03115	COG1620	l-lactate permease
F3L01_RS03130	COG3104	oligopeptide transport
F3L01_RS03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS03165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3L01_RS03175	COG4548	von Willebrand factor, type A
F3L01_RS03180	COG0714	Associated with various cellular activities
F3L01_RS03200	COG0531	amino acid
F3L01_RS03205	COG2188	Transcriptional regulator
F3L01_RS03210	COG1263	PTS System
F3L01_RS03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3L01_RS03215	COG0366	Alpha amylase catalytic
F3L01_RS03230	COG0697	spore germination
F3L01_RS03235	COG4585	Histidine kinase
F3L01_RS03240	COG2197	response regulator
F3L01_RS03245	COG1404	Belongs to the peptidase S8 family
F3L01_RS03255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3L01_RS03260	COG1115	amino acid carrier protein
F3L01_RS03265	COG1126	abc transporter atp-binding protein
F3L01_RS03270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3L01_RS03275	COG0765	amino acid transport
F3L01_RS03280	COG0765	amino acid transport
F3L01_RS03285	COG0833	amino acid
F3L01_RS03310	COG2378	regulation of single-species biofilm formation
F3L01_RS03315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3L01_RS03320	COG5002	protein histidine kinase activity
F3L01_RS03335	COG0659	secondary active sulfate transmembrane transporter activity
F3L01_RS03350	COG2271	Major facilitator Superfamily
F3L01_RS03355	COG1846	Transcriptional regulator
F3L01_RS03360	COG0477	Major facilitator Superfamily
F3L01_RS03365	COG1609	Transcriptional regulator
F3L01_RS03370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3L01_RS03385	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3L01_RS03390	COG1879	ABC-type sugar transport system periplasmic component
F3L01_RS03410	COG1063	alcohol dehydrogenase
F3L01_RS03460	COG0840	transmembrane signaling receptor activity
F3L01_RS03465	COG3583	domain protein
F3L01_RS03465	COG3584	3D domain protein
F3L01_RS03470	COG1476	TRANSCRIPTIONal
F3L01_RS03490	COG3104	oligopeptide transport
F3L01_RS03495	COG1114	Component of the transport system for branched-chain amino acids
F3L01_RS03510	COG1113	amino acid transport
F3L01_RS03515	COG2252	PERMEase
F3L01_RS03530	COG2153	protein acetylation
F3L01_RS03540	COG0569	domain protein
F3L01_RS03540	COG0475	glutathione-regulated potassium exporter activity
F3L01_RS03565	COG0833	amino acid
F3L01_RS03570	COG4990	cell redox homeostasis
F3L01_RS03585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3L01_RS03590	COG0697	spore germination
F3L01_RS03595	COG0531	amino acid
F3L01_RS03605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F3L01_RS03610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F3L01_RS03615	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F3L01_RS03615	COG1918	ferrous iron import across plasma membrane
F3L01_RS03620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3L01_RS03625	COG0573	inorganic phosphate transmembrane transporter activity
F3L01_RS03630	COG0581	inorganic phosphate transmembrane transporter activity
F3L01_RS03635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3L01_RS03755	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F3L01_RS03775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F3L01_RS03780	COG1116	anion transmembrane transporter activity
F3L01_RS03785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3L01_RS03790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3L01_RS03795	COG0352	thiamine-phosphate diphosphorylase activity
F3L01_RS03800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3L01_RS03805	COG2104	thiamine diphosphate biosynthetic process
F3L01_RS03815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3L01_RS03820	COG0351	phosphomethylpyrimidine kinase
F3L01_RS03860	COG2205	protein histidine kinase activity
F3L01_RS03865	COG2814	Major facilitator Superfamily
F3L01_RS03870	COG1846	Transcriptional regulator
F3L01_RS03880	COG2252	PERMEase
F3L01_RS03885	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS03900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3L01_RS03905	COG1621	beta-fructofuranosidase activity
F3L01_RS03910	COG1263	PTS System
F3L01_RS03910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3L01_RS03915	COG1609	Transcriptional regulator
F3L01_RS03965	COG0778	Nitroreductase
F3L01_RS03985	COG2719	SpoVR family
F3L01_RS03995	COG1414	Transcriptional regulator
F3L01_RS04010	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3L01_RS04015	COG1937	Protein conserved in bacteria
F3L01_RS04020	COG0425	Belongs to the sulfur carrier protein TusA family
F3L01_RS04020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS04025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS04030	COG0425	Belongs to the sulfur carrier protein TusA family
F3L01_RS04035	COG0425	Belongs to the sulfur carrier protein TusA family
F3L01_RS04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS04045	COG2210	Belongs to the sulfur carrier protein TusA family
F3L01_RS04050	COG0730	response to heat
F3L01_RS04060	COG1316	TRANSCRIPTIONal
F3L01_RS04065	COG0604	alcohol dehydrogenase
F3L01_RS04070	COG1283	sodium-dependent phosphate transmembrane transporter activity
F3L01_RS04085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3L01_RS04085	COG3711	transcriptional antiterminator
F3L01_RS04090	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3L01_RS04095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3L01_RS04115	COG1388	LysM domain
F3L01_RS04115	COG3584	3D domain protein
F3L01_RS04120	COG0577	efflux transmembrane transporter activity
F3L01_RS04125	COG1136	(ABC) transporter
F3L01_RS04135	COG5522	Integral membrane protein (intg_mem_TP0381)
F3L01_RS04150	COG1114	Component of the transport system for branched-chain amino acids
F3L01_RS04155	COG3546	catalase activity
F3L01_RS04190	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS04225	COG0531	amino acid
F3L01_RS04230	COG0475	glutathione-regulated potassium exporter activity
F3L01_RS04240	COG1737	Transcriptional regulator
F3L01_RS04250	COG1263	PTS System
F3L01_RS04250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3L01_RS04260	COG2259	Doxx family
F3L01_RS04280	COG1522	sequence-specific DNA binding
F3L01_RS04285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F3L01_RS04285	COG0165	Argininosuccinate lyase
F3L01_RS04290	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS04310	COG1309	transcriptional regulator
F3L01_RS04315	COG2814	Major facilitator Superfamily
F3L01_RS04320	COG1733	regulation of RNA biosynthetic process
F3L01_RS04330	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3L01_RS04335	COG4533	DNA binding
F3L01_RS04340	COG2211	Major facilitator Superfamily
F3L01_RS04355	COG0693	protein deglycase activity
F3L01_RS04360	COG0753	catalase activity
F3L01_RS04360	COG0693	protein deglycase activity
F3L01_RS04385	COG1012	belongs to the aldehyde dehydrogenase family
F3L01_RS04390	COG1132	(ABC) transporter
F3L01_RS04395	COG1132	(ABC) transporter
F3L01_RS04400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3L01_RS04405	COG0765	amino acid transport
F3L01_RS04410	COG1126	abc transporter atp-binding protein
F3L01_RS04425	COG0189	ligase activity
F3L01_RS04445	COG4585	Histidine kinase
F3L01_RS04450	COG2197	response regulator
F3L01_RS04455	COG0028	Belongs to the TPP enzyme family
F3L01_RS04460	COG3527	Alpha-acetolactate decarboxylase
F3L01_RS04470	COG0561	phosphatase activity
F3L01_RS04480	COG3409	Peptidoglycan-binding domain 1 protein
F3L01_RS04480	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS04485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3L01_RS04490	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS04505	COG0659	secondary active sulfate transmembrane transporter activity
F3L01_RS04510	COG2244	polysaccharide biosynthetic process
F3L01_RS04530	COG1024	Enoyl-CoA hydratase
F3L01_RS04550	COG1363	Peptidase, m42
F3L01_RS04585	COG0601	transmembrane transport
F3L01_RS04590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3L01_RS04595	COG0444	Belongs to the ABC transporter superfamily
F3L01_RS04600	COG4608	Belongs to the ABC transporter superfamily
F3L01_RS04610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS04800	COG0477	Major facilitator Superfamily
F3L01_RS04805	COG3290	protein histidine kinase activity
F3L01_RS04810	COG4565	transcriptional regulatory protein
F3L01_RS04815	COG3181	Tripartite tricarboxylate transporter family receptor
F3L01_RS04855	COG0789	Transcriptional regulator
F3L01_RS04855	COG4978	Transcriptional regulator
F3L01_RS04870	COG0305	Participates in initiation and elongation during chromosome replication
F3L01_RS04905	COG0477	Major facilitator Superfamily
F3L01_RS04920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS04940	COG1073	alpha beta
F3L01_RS04970	COG1183	phosphatidylcholine synthase activity
F3L01_RS04985	COG2376	Dihydroxyacetone kinase
F3L01_RS04995	COG2376	Dihydroxyacetone kinase
F3L01_RS05025	COG2373	Large extracellular alpha-helical protein
F3L01_RS05045	COG0596	Alpha beta hydrolase
F3L01_RS05095	COG1191	sigma factor activity
F3L01_RS05105	COG2208	phosphoserine phosphatase activity
F3L01_RS05110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3L01_RS05115	COG0784	Response regulator, receiver
F3L01_RS05115	COG2205	protein histidine kinase activity
F3L01_RS05115	COG5002	protein histidine kinase activity
F3L01_RS05160	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
F3L01_RS05180	COG0420	3'-5' exonuclease activity
F3L01_RS05185	COG4717	serine-type aminopeptidase activity
F3L01_RS05195	COG0346	lactoylglutathione lyase activity
F3L01_RS05200	COG0346	lactoylglutathione lyase activity
F3L01_RS05205	COG0457	Tetratricopeptide repeat
F3L01_RS05215	COG2267	carboxylic ester hydrolase activity
F3L01_RS05240	COG2140	Oxalate decarboxylase
F3L01_RS05245	COG3620	sequence-specific DNA binding
F3L01_RS05250	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
F3L01_RS05255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3L01_RS05265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3L01_RS05270	COG1695	Transcriptional regulator
F3L01_RS05285	COG1595	DNA-templated transcription, initiation
F3L01_RS05310	COG3973	AAA domain
F3L01_RS05340	COG4980	gas vesicle protein
F3L01_RS05345	COG0537	adenosine 5'-monophosphoramidase activity
F3L01_RS05350	COG1131	(ABC) transporter
F3L01_RS05355	COG4473	ABC transporter
F3L01_RS05380	COG3402	PFAM membrane-flanked domain
F3L01_RS05385	COG3428	Bacterial PH domain
F3L01_RS05415	COG0697	spore germination
F3L01_RS05420	COG3402	PFAM membrane-flanked domain
F3L01_RS05425	COG3428	Bacterial PH domain
F3L01_RS05430	COG2329	Antibiotic biosynthesis monooxygenase
F3L01_RS05435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3L01_RS05485	COG1309	transcriptional regulator
F3L01_RS05490	COG1511	domain protein
F3L01_RS05510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS05515	COG1609	Transcriptional regulator
F3L01_RS05525	COG1234	tRNA 3'-trailer cleavage
F3L01_RS05530	COG0095	Lipoate-protein ligase
F3L01_RS05540	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS05550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3L01_RS05560	COG4208	sulfate ABC transporter
F3L01_RS05635	COG1408	metallophosphoesterase
F3L01_RS05640	COG1078	dGTPase activity
F3L01_RS05650	COG1595	DNA-templated transcription, initiation
F3L01_RS05655	COG2207	Transcriptional regulator
F3L01_RS05655	COG3708	Transcriptional regulator
F3L01_RS05665	COG2205	protein histidine kinase activity
F3L01_RS05670	COG0745	RESPONSE REGULATOR receiver
F3L01_RS05685	COG0501	Belongs to the peptidase M48B family
F3L01_RS05690	COG0840	transmembrane signaling receptor activity
F3L01_RS05695	COG3693	PFAM glycoside hydrolase, family 10
F3L01_RS05705	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3L01_RS05710	COG2224	Isocitrate lyase
F3L01_RS05745	COG0398	Pfam SNARE associated Golgi protein
F3L01_RS05765	COG0202	RNA polymerase activity
F3L01_RS05805	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3L01_RS05840	COG0753	catalase activity
F3L01_RS05845	COG0004	ammonium transporteR
F3L01_RS05865	COG2996	Protein conserved in bacteria
F3L01_RS05870	COG3209	COG3209 Rhs family protein
F3L01_RS05890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS05905	COG0561	phosphatase activity
F3L01_RS05925	COG2267	carboxylic ester hydrolase activity
F3L01_RS05945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3L01_RS05950	COG5504	Zn-dependent protease
F3L01_RS05960	COG0180	Tryptophanyl-tRNA synthetase
F3L01_RS05975	COG0601	transmembrane transport
F3L01_RS05980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3L01_RS05985	COG0444	Belongs to the ABC transporter superfamily
F3L01_RS05990	COG4608	Belongs to the ABC transporter superfamily
F3L01_RS05995	COG0534	Mate efflux family protein
F3L01_RS06000	COG4166	transmembrane transport
F3L01_RS06015	COG0861	Integral membrane protein TerC family
F3L01_RS06035	COG1164	Oligoendopeptidase f
F3L01_RS06050	COG2346	COG2346, Truncated hemoglobins
F3L01_RS06055	COG4116	CYTH
F3L01_RS06065	COG2357	RelA SpoT domain protein
F3L01_RS06075	COG0564	pseudouridine synthase activity
F3L01_RS06090	COG0772	Belongs to the SEDS family
F3L01_RS06095	COG1216	Glycosyl transferase, family 2
F3L01_RS06115	COG0463	Glycosyl transferase, family 2
F3L01_RS06115	COG0457	Tetratricopeptide repeat
F3L01_RS06135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F3L01_RS06150	COG1091	dTDP-4-dehydrorhamnose reductase activity
F3L01_RS06195	COG2153	protein acetylation
F3L01_RS06205	COG2382	esterase
F3L01_RS06225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3L01_RS06235	COG0512	Glutamine amidotransferase of anthranilate synthase
F3L01_RS06235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3L01_RS06270	COG1620	l-lactate permease
F3L01_RS06275	COG5634	Uncharacterized conserved protein (DUF2278)
F3L01_RS06325	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3L01_RS06360	COG4152	abc transporter atp-binding protein
F3L01_RS06365	COG1668	transmembrane transport
F3L01_RS06395	COG1686	Belongs to the peptidase S11 family
F3L01_RS06400	COG0681	Belongs to the peptidase S26 family
F3L01_RS06435	COG1012	belongs to the aldehyde dehydrogenase family
F3L01_RS06445	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3L01_RS06450	COG1177	transmembrane transport
F3L01_RS06465	COG2409	Drug exporters of the RND superfamily
F3L01_RS06475	COG0564	pseudouridine synthase activity
F3L01_RS06485	COG2340	Cysteine-rich secretory protein family
F3L01_RS06490	COG0247	lactate metabolic process
F3L01_RS06495	COG0277	FAD linked oxidase domain protein
F3L01_RS06500	COG3835	regulator
F3L01_RS06510	COG0745	RESPONSE REGULATOR receiver
F3L01_RS06515	COG5002	protein histidine kinase activity
F3L01_RS06520	COG2186	Transcriptional regulator
F3L01_RS06540	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F3L01_RS06550	COG2116	formate transmembrane transporter activity
F3L01_RS06555	COG0861	Integral membrane protein TerC family
F3L01_RS06560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3L01_RS06570	COG2030	dehydratase
F3L01_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS06595	COG3243	poly(R)-hydroxyalkanoic acid synthase
F3L01_RS06605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3L01_RS06620	COG1840	ABC-type Fe3 transport system, periplasmic component
F3L01_RS06625	COG3842	ATPase activity
F3L01_RS06650	COG1349	DNA-binding transcription factor activity
F3L01_RS06660	COG0235	Class ii aldolase
F3L01_RS06670	COG2861	carbohydrate metabolic process
F3L01_RS06680	COG3852	Histidine kinase
F3L01_RS06685	COG1846	Transcriptional regulator
F3L01_RS06695	COG2318	DinB family
F3L01_RS06700	COG5002	protein histidine kinase activity
F3L01_RS06710	COG0720	synthase
F3L01_RS06725	COG4873	Protein conserved in bacteria
F3L01_RS06755	COG1780	Probably involved in ribonucleotide reductase function
F3L01_RS06760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3L01_RS06765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3L01_RS06770	COG1725	Transcriptional regulator
F3L01_RS06775	COG1131	(ABC) transporter
F3L01_RS06785	COG1131	(ABC) transporter
F3L01_RS06805	COG1522	sequence-specific DNA binding
F3L01_RS06815	COG1335	isochorismatase
F3L01_RS06825	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3L01_RS06830	COG2070	2-Nitropropane dioxygenase
F3L01_RS06835	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
F3L01_RS06845	COG1696	Membrane protein involved in D-alanine export
F3L01_RS06870	COG0716	FMN binding
F3L01_RS06925	COG1846	Transcriptional regulator
F3L01_RS06935	COG1301	dicarboxylic acid transport
F3L01_RS06940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3L01_RS06945	COG4709	membrane
F3L01_RS06950	COG3874	Sporulation protein YtfJ
F3L01_RS06970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3L01_RS06975	COG0028	Belongs to the TPP enzyme family
F3L01_RS06980	COG0440	acetolactate synthase activity
F3L01_RS07070	COG1183	phosphatidylcholine synthase activity
F3L01_RS07075	COG1368	sulfuric ester hydrolase activity
F3L01_RS07085	COG0019	diaminopimelate decarboxylase activity
F3L01_RS07105	COG0529	Catalyzes the synthesis of activated sulfate
F3L01_RS07110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3L01_RS07130	COG1648	precorrin-2 dehydrogenase activity
F3L01_RS07135	COG0733	neurotransmitter:sodium symporter activity
F3L01_RS07160	COG1757	Na H antiporter
F3L01_RS07175	COG4758	membrane
F3L01_RS07180	COG4585	Histidine kinase
F3L01_RS07185	COG2197	response regulator
F3L01_RS07195	COG1114	Component of the transport system for branched-chain amino acids
F3L01_RS07245	COG0730	response to heat
F3L01_RS07250	COG0306	phosphate transporter
F3L01_RS07255	COG1392	Phosphate transport regulator
F3L01_RS07260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3L01_RS07275	COG3852	Histidine kinase
F3L01_RS07280	COG1801	Protein of unknown function DUF72
F3L01_RS07290	COG0582	viral genome integration into host DNA
F3L01_RS07295	COG5002	protein histidine kinase activity
F3L01_RS07310	COG0392	lysyltransferase activity
F3L01_RS07310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F3L01_RS07325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3L01_RS07330	COG1686	Belongs to the peptidase S11 family
F3L01_RS07335	COG2715	membrane protein required for spore maturation
F3L01_RS07340	COG0700	Nucleoside recognition
F3L01_RS07345	COG1187	pseudouridine synthase activity
F3L01_RS07355	COG1333	cytochrome c biogenesis protein
F3L01_RS07360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3L01_RS07365	COG0745	RESPONSE REGULATOR receiver
F3L01_RS07370	COG5002	protein histidine kinase activity
F3L01_RS07375	COG2096	Adenosyltransferase
F3L01_RS07390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
F3L01_RS07395	COG1141	Ferredoxin
F3L01_RS07405	COG0514	ATP-dependent DNA helicase (RecQ)
F3L01_RS07410	COG1266	CAAX protease self-immunity
F3L01_RS07420	COG1408	metallophosphoesterase
F3L01_RS07425	COG0789	Transcriptional regulator
F3L01_RS07435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3L01_RS07455	COG0492	ferredoxin-NADP+ reductase activity
F3L01_RS07460	COG0252	asparaginase activity
F3L01_RS07530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F3L01_RS07545	COG0142	geranyltranstransferase activity
F3L01_RS07555	COG0142	geranyltranstransferase activity
F3L01_RS07580	COG0457	Tetratricopeptide repeat
F3L01_RS07600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3L01_RS07605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3L01_RS07605	COG2010	Cytochrome c
F3L01_RS07610	COG4347	Protein of unknown function (DUF1405)
F3L01_RS07625	COG2738	Putative neutral zinc metallopeptidase
F3L01_RS07635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS07640	COG1694	Mazg nucleotide pyrophosphohydrolase
F3L01_RS07660	COG0438	transferase activity, transferring glycosyl groups
F3L01_RS07695	COG1199	ATP-dependent helicase activity
F3L01_RS07695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3L01_RS07715	COG3935	DnaD domain protein
F3L01_RS07720	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3L01_RS07730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3L01_RS07730	COG4499	WXG100 protein secretion system (Wss), protein YukC
F3L01_RS07785	COG0116	Belongs to the methyltransferase superfamily
F3L01_RS07805	COG0457	Tetratricopeptide repeat
F3L01_RS07825	COG1199	ATP-dependent helicase activity
F3L01_RS07830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F3L01_RS07840	COG0024	Methionine aminopeptidase
F3L01_RS07850	COG2233	PERMEase
F3L01_RS07855	COG2311	Membrane
F3L01_RS07860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F3L01_RS07870	COG0456	acetyltransferase
F3L01_RS07920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3L01_RS07935	COG3944	biosynthesis protein
F3L01_RS07945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3L01_RS07960	COG1215	transferase activity, transferring glycosyl groups
F3L01_RS07965	COG0438	transferase activity, transferring glycosyl groups
F3L01_RS07980	COG0454	-acetyltransferase
F3L01_RS08000	COG0328	RNA-DNA hybrid ribonuclease activity
F3L01_RS08035	COG3403	YqcI/YcgG family
F3L01_RS08040	COG1280	lysine exporter protein (LysE YggA)
F3L01_RS08060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3L01_RS08065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3L01_RS08075	COG0475	glutathione-regulated potassium exporter activity
F3L01_RS08080	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F3L01_RS08085	COG0789	Transcriptional regulator
F3L01_RS08085	COG4978	Transcriptional regulator
F3L01_RS08095	COG2323	membrane
F3L01_RS08100	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F3L01_RS08135	COG1923	regulation of RNA biosynthetic process
F3L01_RS08145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3L01_RS08150	COG1360	Flagellar Motor Protein
F3L01_RS08155	COG2201	protein-glutamate methylesterase activity
F3L01_RS08160	COG2198	Histidine kinase
F3L01_RS08160	COG0643	Histidine kinase
F3L01_RS08165	COG1776	CheC inhibitor of MCP methylation
F3L01_RS08165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3L01_RS08180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3L01_RS08200	COG1256	bacterial-type flagellum assembly
F3L01_RS08205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3L01_RS08210	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F3L01_RS08225	COG1815	bacterial-type flagellum-dependent cell motility
F3L01_RS08230	COG1558	bacterial-type flagellum-dependent cell motility
F3L01_RS08245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3L01_RS08255	COG1157	protein secretion by the type III secretion system
F3L01_RS08290	COG0784	Response regulator, receiver
F3L01_RS08290	COG0835	chemotaxis
F3L01_RS08300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3L01_RS08305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3L01_RS08310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3L01_RS08315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3L01_RS08320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3L01_RS08325	COG0741	lytic transglycosylase activity
F3L01_RS08335	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3L01_RS08340	COG1776	CheC inhibitor of MCP methylation
F3L01_RS08340	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3L01_RS08350	COG1338	Plays a role in the flagellum-specific transport system
F3L01_RS08355	COG1987	bacterial-type flagellum assembly
F3L01_RS08365	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3L01_RS08370	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3L01_RS08380	COG1419	protein localization to endoplasmic reticulum
F3L01_RS08385	COG4786	Flagellar basal body rod
F3L01_RS08390	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3L01_RS08425	COG2329	Antibiotic biosynthesis monooxygenase
F3L01_RS08450	COG0583	DNA-binding transcription factor activity
F3L01_RS08500	COG0406	alpha-ribazole phosphatase activity
F3L01_RS08530	COG0367	asparagine synthase
F3L01_RS08560	COG1802	Transcriptional regulator
F3L01_RS08575	COG0523	cobalamin synthesis protein
F3L01_RS08580	COG0701	Predicted permease
F3L01_RS08595	COG1757	Na H antiporter
F3L01_RS08600	COG0789	Transcriptional regulator
F3L01_RS08625	COG0534	Mate efflux family protein
F3L01_RS08630	COG3340	Belongs to the peptidase S51 family
F3L01_RS08655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3L01_RS08670	COG0457	Tetratricopeptide repeat
F3L01_RS08690	COG2733	membrane
F3L01_RS08725	COG1131	(ABC) transporter
F3L01_RS08740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3L01_RS08745	COG0528	UMP kinase activity
F3L01_RS08760	COG1027	Aspartate ammonia-lyase
F3L01_RS08765	COG0281	malic enzyme
F3L01_RS08770	COG4191	Histidine kinase
F3L01_RS08775	COG0784	Response regulator, receiver
F3L01_RS08780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F3L01_RS08825	COG2814	Major facilitator Superfamily
F3L01_RS08840	COG1695	Transcriptional regulator
F3L01_RS08855	COG0477	Major facilitator Superfamily
F3L01_RS08865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3L01_RS08870	COG2223	nitrite transmembrane transporter activity
F3L01_RS08875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3L01_RS08895	COG0733	neurotransmitter:sodium symporter activity
F3L01_RS08905	COG5566	PFAM Mor transcription activator
F3L01_RS08910	COG2323	membrane
F3L01_RS08930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3L01_RS08940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3L01_RS08945	COG0028	Belongs to the TPP enzyme family
F3L01_RS08965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3L01_RS08995	COG3384	dioxygenase
F3L01_RS09005	COG3279	Response regulator of the LytR AlgR family
F3L01_RS09010	COG0427	acetyl-CoA hydrolase
F3L01_RS09030	COG4166	transmembrane transport
F3L01_RS09055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS09075	COG1914	H( )-stimulated, divalent metal cation uptake system
F3L01_RS09090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3L01_RS09095	COG0531	amino acid
F3L01_RS09130	COG1309	transcriptional regulator
F3L01_RS09135	COG2390	Transcriptional regulator
F3L01_RS09145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS09150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F3L01_RS09185	COG4846	Membrane protein involved in cytochrome C biogenesis
F3L01_RS09195	COG0006	proline dipeptidase activity
F3L01_RS09205	COG2132	Multicopper oxidase
F3L01_RS09235	COG1114	Component of the transport system for branched-chain amino acids
F3L01_RS09245	COG2372	response to copper ion
F3L01_RS09245	COG1276	copper resistance
F3L01_RS09250	COG4549	nuclear export factor GLE1
F3L01_RS09255	COG0697	spore germination
F3L01_RS09260	COG0583	DNA-binding transcription factor activity
F3L01_RS09265	COG1959	2 iron, 2 sulfur cluster binding
F3L01_RS09270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F3L01_RS09275	COG0778	Nitroreductase
F3L01_RS09285	COG0628	permease
F3L01_RS09295	COG1231	oxidoreductase activity
F3L01_RS09300	COG0523	cobalamin synthesis protein
F3L01_RS09310	COG0411	ABC transporter
F3L01_RS09330	COG0583	DNA-binding transcription factor activity
F3L01_RS09360	COG1271	oxidase subunit
F3L01_RS09365	COG1294	oxidase, subunit
F3L01_RS09370	COG4988	ABC transporter
F3L01_RS09375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3L01_RS09385	COG1216	Glycosyl transferase, family 2
F3L01_RS09425	COG1686	Belongs to the peptidase S11 family
F3L01_RS09440	COG0791	NLP P60 protein
F3L01_RS09440	COG1388	LysM domain
F3L01_RS09450	COG1132	(ABC) transporter
F3L01_RS09455	COG0745	RESPONSE REGULATOR receiver
F3L01_RS09460	COG5002	protein histidine kinase activity
F3L01_RS09470	COG0300	oxidoreductase activity
F3L01_RS09500	COG0460	homoserine dehydrogenase
F3L01_RS09525	COG1316	TRANSCRIPTIONal
F3L01_RS09535	COG0745	RESPONSE REGULATOR receiver
F3L01_RS09540	COG5002	protein histidine kinase activity
F3L01_RS09555	COG1285	pathogenesis
F3L01_RS09560	COG1247	-acetyltransferase
F3L01_RS09570	COG4264	IucA IucC family
F3L01_RS09575	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS09590	COG1082	Xylose isomerase domain protein TIM barrel
F3L01_RS09600	COG2814	Major facilitator Superfamily
F3L01_RS09605	COG1279	arginine transmembrane transporter activity
F3L01_RS09610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS09620	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3L01_RS09655	COG0577	efflux transmembrane transporter activity
F3L01_RS09660	COG2002	toxin-antitoxin pair type II binding
F3L01_RS09665	COG1404	Belongs to the peptidase S8 family
F3L01_RS09670	COG0640	Transcriptional regulator
F3L01_RS09675	COG0667	Aldo Keto reductase
F3L01_RS09680	COG2814	Major facilitator Superfamily
F3L01_RS09685	COG3152	Membrane
F3L01_RS09710	COG0840	transmembrane signaling receptor activity
F3L01_RS09725	COG3949	Membrane
F3L01_RS09730	COG0783	Belongs to the Dps family
F3L01_RS09745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3L01_RS09755	COG1231	oxidoreductase activity
F3L01_RS09760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS09765	COG4989	oxidoreductase activity
F3L01_RS09770	COG0523	cobalamin synthesis protein
F3L01_RS09775	COG0456	acetyltransferase
F3L01_RS09780	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3L01_RS09790	COG0702	epimerase
F3L01_RS09800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3L01_RS09810	COG4166	transmembrane transport
F3L01_RS09840	COG1051	belongs to the nudix hydrolase family
F3L01_RS09845	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS09860	COG0701	Predicted permease
F3L01_RS09865	COG3689	TIGRFAM TIGR03943 family protein
F3L01_RS09880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3L01_RS09895	COG0702	epimerase
F3L01_RS09900	COG2839	Protein conserved in bacteria
F3L01_RS09905	COG1253	flavin adenine dinucleotide binding
F3L01_RS09920	COG1114	Component of the transport system for branched-chain amino acids
F3L01_RS09925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3L01_RS09945	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS09955	COG1876	peptidase activity
F3L01_RS09965	COG0154	amidase activity
F3L01_RS09970	COG2211	Major facilitator Superfamily
F3L01_RS10015	COG0798	PFAM Bile acid sodium symporter
F3L01_RS10020	COG0640	Transcriptional regulator
F3L01_RS10090	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS10100	COG0561	phosphatase activity
F3L01_RS10115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3L01_RS10130	COG1819	glycosyl
F3L01_RS10135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS10140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS10170	COG0456	acetyltransferase
F3L01_RS10205	COG4499	WXG100 protein secretion system (Wss), protein YukC
F3L01_RS10280	COG3874	Sporulation protein YtfJ
F3L01_RS10305	COG2226	methyltransferase
F3L01_RS10325	COG1082	Xylose isomerase domain protein TIM barrel
F3L01_RS10330	COG0346	lactoylglutathione lyase activity
F3L01_RS10340	COG0604	alcohol dehydrogenase
F3L01_RS10345	COG1595	DNA-templated transcription, initiation
F3L01_RS10355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F3L01_RS10365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3L01_RS10365	COG0426	domain, Protein
F3L01_RS10375	COG0386	Belongs to the glutathione peroxidase family
F3L01_RS10385	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
F3L01_RS10395	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F3L01_RS10400	COG1140	nitrate reductase beta subunit
F3L01_RS10405	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F3L01_RS10410	COG2181	nitrate reductase activity
F3L01_RS10415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3L01_RS10420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3L01_RS10425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3L01_RS10430	COG0303	'Molybdopterin
F3L01_RS10435	COG0314	molybdopterin synthase activity
F3L01_RS10445	COG2223	nitrite transmembrane transporter activity
F3L01_RS10465	COG1648	precorrin-2 dehydrogenase activity
F3L01_RS10475	COG1587	Uroporphyrinogen-III synthase
F3L01_RS10475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3L01_RS10480	COG2146	nitrite reductase [NAD(P)H] activity
F3L01_RS10485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3L01_RS10490	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
F3L01_RS10525	COG2359	stage V sporulation protein S
F3L01_RS10550	COG0457	Tetratricopeptide repeat
F3L01_RS10565	COG1418	mRNA catabolic process
F3L01_RS10585	COG0629	single-stranded DNA binding
F3L01_RS10605	COG2521	methyltransferase
F3L01_RS10605	COG2136	Putative SAM-dependent methyltransferase
F3L01_RS10610	COG0018	arginyl-trna synthetase
F3L01_RS10650	COG0017	Asparaginyl-tRNA synthetase
F3L01_RS10655	COG0733	neurotransmitter:sodium symporter activity
F3L01_RS10680	COG2610	gluconate transmembrane transporter activity
F3L01_RS10690	COG1794	racemase activity, acting on amino acids and derivatives
F3L01_RS10700	COG0456	acetyltransferase
F3L01_RS10710	COG3655	Transcriptional regulator
F3L01_RS10715	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F3L01_RS10725	COG1131	(ABC) transporter
F3L01_RS10730	COG4473	ABC transporter
F3L01_RS10740	COG0546	phosphoglycolate phosphatase activity
F3L01_RS10755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3L01_RS10780	COG0768	penicillin binding
F3L01_RS10790	COG0204	Acyl-transferase
F3L01_RS10795	COG1272	protein, Hemolysin III
F3L01_RS10805	COG0805	protein transport
F3L01_RS10815	COG1307	EDD domain protein, DegV family
F3L01_RS10825	COG1999	signal sequence binding
F3L01_RS10830	COG0071	Belongs to the small heat shock protein (HSP20) family
F3L01_RS10835	COG0367	asparagine synthase
F3L01_RS10860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3L01_RS10880	COG1335	isochorismatase
F3L01_RS10890	COG0668	transmembrane transport
F3L01_RS10895	COG4585	Histidine kinase
F3L01_RS10895	COG2203	Gaf domain
F3L01_RS10905	COG1737	Transcriptional regulator
F3L01_RS10940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F3L01_RS10980	COG1174	glycine betaine transport
F3L01_RS11015	COG1253	flavin adenine dinucleotide binding
F3L01_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
F3L01_RS11025	COG5506	Protein of unknown function (DUF1694)
F3L01_RS11040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3L01_RS11045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3L01_RS11050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3L01_RS11055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3L01_RS11060	COG0456	acetyltransferase
F3L01_RS11065	COG3829	transcription factor binding
F3L01_RS11070	COG1509	lysine 2,3-aminomutase activity
F3L01_RS11105	COG0515	serine threonine protein kinase
F3L01_RS11105	COG3064	Membrane
F3L01_RS11105	COG4991	sh3 domain protein
F3L01_RS11115	COG0671	phosphoesterase, PA-phosphatase related
F3L01_RS11120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3L01_RS11125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3L01_RS11210	COG0300	oxidoreductase activity
F3L01_RS11230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3L01_RS11230	COG4499	WXG100 protein secretion system (Wss), protein YukC
F3L01_RS11240	COG2814	Major facilitator Superfamily
F3L01_RS11245	COG4841	protein insertion into membrane
F3L01_RS11255	COG2079	MmgE PrpD family protein
F3L01_RS11260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F3L01_RS11265	COG1960	acyl-CoA dehydrogenase activity
F3L01_RS11270	COG2084	Dehydrogenase
F3L01_RS11280	COG1280	lysine exporter protein (LysE YggA)
F3L01_RS11285	COG1024	Enoyl-CoA hydratase
F3L01_RS11300	COG0420	3'-5' exonuclease activity
F3L01_RS11305	COG0419	ATPase involved in DNA repair
F3L01_RS11330	COG2223	nitrite transmembrane transporter activity
F3L01_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS11340	COG1169	isochorismate synthase
F3L01_RS11345	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3L01_RS11350	COG1535	isochorismatase
F3L01_RS11350	COG3433	isochorismatase activity
F3L01_RS11355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3L01_RS11360	COG3251	PFAM MbtH domain protein
F3L01_RS11365	COG2814	Major facilitator Superfamily
F3L01_RS11380	COG0776	regulation of translation
F3L01_RS11390	COG2318	DinB family
F3L01_RS11400	COG1115	amino acid carrier protein
F3L01_RS11420	COG1187	pseudouridine synthase activity
F3L01_RS11430	COG1136	(ABC) transporter
F3L01_RS11455	COG0028	Belongs to the TPP enzyme family
F3L01_RS11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS11590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS11650	COG2258	MOSC domain
F3L01_RS11670	COG1132	(ABC) transporter
F3L01_RS11700	COG1396	sequence-specific DNA binding
F3L01_RS11730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3L01_RS11735	COG1595	DNA-templated transcription, initiation
F3L01_RS11760	COG1649	PFAM Uncharacterised BCR, COG1649
F3L01_RS11785	COG2971	BadF BadG BcrA BcrD
F3L01_RS11795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F3L01_RS11805	COG1846	Transcriptional regulator
F3L01_RS11825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS11845	COG1309	transcriptional regulator
F3L01_RS11895	COG0582	viral genome integration into host DNA
F3L01_RS11950	COG0500	methyltransferase
F3L01_RS11950	COG3615	Tellurite resistance protein tehB
F3L01_RS11960	COG2226	methyltransferase
F3L01_RS11965	COG3961	Belongs to the TPP enzyme family
F3L01_RS11970	COG1846	Transcriptional regulator
F3L01_RS12000	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3L01_RS12025	COG2002	toxin-antitoxin pair type II binding
F3L01_RS12035	COG0730	response to heat
F3L01_RS12040	COG0110	maltose O-acetyltransferase activity
F3L01_RS12045	COG1686	Belongs to the peptidase S11 family
F3L01_RS12060	COG2814	Major facilitator Superfamily
F3L01_RS12095	COG2312	Erythromycin esterase
F3L01_RS12100	COG0741	lytic transglycosylase activity
F3L01_RS12105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS12170	COG0577	efflux transmembrane transporter activity
F3L01_RS12175	COG1136	(ABC) transporter
F3L01_RS12210	COG0768	penicillin binding
F3L01_RS12225	COG1408	metallophosphoesterase
F3L01_RS12235	COG1131	(ABC) transporter
F3L01_RS12245	COG1309	transcriptional regulator
F3L01_RS12260	COG1960	acyl-CoA dehydrogenase activity
F3L01_RS12265	COG0439	Biotin carboxylase
F3L01_RS12270	COG0511	ligase activity, forming carbon-carbon bonds
F3L01_RS12275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3L01_RS12280	COG1024	Enoyl-CoA hydratase
F3L01_RS12285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3L01_RS12290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3L01_RS12335	COG1686	Belongs to the peptidase S11 family
F3L01_RS12360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3L01_RS12380	COG2207	Transcriptional regulator
F3L01_RS12410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3L01_RS12440	COG1942	4-Oxalocrotonate Tautomerase
F3L01_RS12445	COG0583	DNA-binding transcription factor activity
F3L01_RS12470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS12480	COG2368	4-hydroxyphenylacetate
F3L01_RS12495	COG1063	alcohol dehydrogenase
F3L01_RS12505	COG2323	membrane
F3L01_RS12510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3L01_RS12520	COG3386	PFAM SMP-30 Gluconolaconase
F3L01_RS12535	COG3773	Cell wall hydrolase
F3L01_RS12540	COG0596	Alpha beta hydrolase
F3L01_RS12550	COG0745	RESPONSE REGULATOR receiver
F3L01_RS12555	COG2205	protein histidine kinase activity
F3L01_RS12575	COG1136	(ABC) transporter
F3L01_RS12580	COG0577	efflux transmembrane transporter activity
F3L01_RS12600	COG0460	homoserine dehydrogenase
F3L01_RS12605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS12615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F3L01_RS12670	COG2124	cytochrome p450
F3L01_RS12705	COG0561	phosphatase activity
F3L01_RS12710	COG5002	protein histidine kinase activity
F3L01_RS12725	COG1819	glycosyl
F3L01_RS12730	COG1794	racemase activity, acting on amino acids and derivatives
F3L01_RS12760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3L01_RS12775	COG3708	Transcriptional regulator
F3L01_RS12775	COG2207	Transcriptional regulator
F3L01_RS12810	COG1335	isochorismatase
F3L01_RS12830	COG0546	phosphoglycolate phosphatase activity
F3L01_RS12840	COG0519	Catalyzes the synthesis of GMP from XMP
F3L01_RS12900	COG2205	protein histidine kinase activity
F3L01_RS12915	COG0604	alcohol dehydrogenase
F3L01_RS12920	COG0671	phosphoesterase, PA-phosphatase related
F3L01_RS12980	COG2814	Major facilitator Superfamily
F3L01_RS12995	COG0584	glycerophosphoryl diester phosphodiesterase
F3L01_RS13015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS13020	COG0697	spore germination
F3L01_RS13065	COG2223	nitrite transmembrane transporter activity
F3L01_RS13085	COG0592	DNA-directed DNA polymerase activity
F3L01_RS13105	COG0251	oxidation-reduction process
F3L01_RS13110	COG3878	Protein conserved in bacteria
F3L01_RS13130	COG4667	esterase of the alpha-beta hydrolase superfamily
F3L01_RS13170	COG0322	excinuclease ABC activity
F3L01_RS13200	COG1131	(ABC) transporter
F3L01_RS13220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3L01_RS13255	COG1011	Hydrolase
F3L01_RS13270	COG1073	alpha beta
F3L01_RS13275	COG1523	belongs to the glycosyl hydrolase 13 family
F3L01_RS13280	COG3227	Zinc metalloprotease (Elastase)
F3L01_RS13285	COG0737	Belongs to the 5'-nucleotidase family
F3L01_RS13300	COG0201	protein transport
F3L01_RS13305	COG0697	spore germination
F3L01_RS13310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS13315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3L01_RS13345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS13400	COG1309	transcriptional regulator
F3L01_RS13420	COG3284	Transcriptional regulator
F3L01_RS13435	COG1349	DNA-binding transcription factor activity
F3L01_RS13450	COG1959	2 iron, 2 sulfur cluster binding
F3L01_RS13465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3L01_RS13470	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3L01_RS13480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3L01_RS13495	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS13525	COG4176	ABC-type proline glycine betaine transport system permease component
F3L01_RS13530	COG0517	IMP dehydrogenase activity
F3L01_RS13530	COG4175	Glycine betaine
F3L01_RS13560	COG2153	protein acetylation
F3L01_RS13565	COG3397	chitin binding
F3L01_RS13570	COG1819	glycosyl
F3L01_RS13590	COG2205	protein histidine kinase activity
F3L01_RS13595	COG2226	methyltransferase
F3L01_RS13600	COG2315	Protein conserved in bacteria
F3L01_RS13645	COG3973	AAA domain
F3L01_RS13670	COG0514	ATP-dependent DNA helicase (RecQ)
F3L01_RS13705	COG4637	Psort location Cytoplasmic, score
F3L01_RS13720	COG3397	chitin binding
F3L01_RS13735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3L01_RS13740	COG1115	amino acid carrier protein
F3L01_RS13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3L01_RS13760	COG3938	Belongs to the proline racemase family
F3L01_RS13765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3L01_RS13805	COG1078	dGTPase activity
F3L01_RS13810	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS13830	COG4166	transmembrane transport
F3L01_RS13840	COG4948	Mandelate Racemase Muconate Lactonizing
F3L01_RS13855	COG0667	Aldo Keto reductase
F3L01_RS13900	COG5002	protein histidine kinase activity
F3L01_RS13900	COG3850	Histidine kinase
F3L01_RS13905	COG0745	RESPONSE REGULATOR receiver
F3L01_RS13950	COG1307	EDD domain protein, DegV family
F3L01_RS13990	COG2814	Major facilitator Superfamily
F3L01_RS14000	COG1664	Polymer-forming cytoskeletal
F3L01_RS14005	COG0789	Transcriptional regulator
F3L01_RS14010	COG4533	DNA binding
F3L01_RS14015	COG0477	Major facilitator Superfamily
F3L01_RS14015	COG2814	Major facilitator Superfamily
F3L01_RS14035	COG2261	transglycosylase associated protein
F3L01_RS14050	COG2226	methyltransferase
F3L01_RS14085	COG0436	Aminotransferase
F3L01_RS14090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3L01_RS14100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3L01_RS14140	COG0628	permease
F3L01_RS14150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3L01_RS14155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3L01_RS14160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3L01_RS14200	COG2746	aminoglycoside 3-N-acetyltransferase activity
F3L01_RS14210	COG0697	spore germination
F3L01_RS14215	COG2318	DinB family
F3L01_RS14235	COG4912	Dna alkylation repair
F3L01_RS14240	COG0346	lactoylglutathione lyase activity
F3L01_RS14245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS14260	COG0861	Integral membrane protein TerC family
F3L01_RS14265	COG1368	sulfuric ester hydrolase activity
F3L01_RS14270	COG0488	(ABC) transporter
F3L01_RS14310	COG0582	viral genome integration into host DNA
F3L01_RS14345	COG4974	Belongs to the 'phage' integrase family
F3L01_RS14355	COG2409	Drug exporters of the RND superfamily
F3L01_RS14355	COG1033	growth of symbiont in host cell
F3L01_RS14360	COG1309	transcriptional regulator
F3L01_RS14375	COG0287	Prephenate dehydrogenase
F3L01_RS14390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
F3L01_RS14390	COG1605	Chorismate mutase
F3L01_RS14435	COG1388	LysM domain
F3L01_RS14435	COG3584	3D domain protein
F3L01_RS14445	COG0346	lactoylglutathione lyase activity
F3L01_RS14450	COG0277	FAD linked oxidase domain protein
F3L01_RS14475	COG1879	ABC-type sugar transport system periplasmic component
F3L01_RS14480	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3L01_RS14485	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3L01_RS14495	COG2390	Transcriptional regulator
F3L01_RS14500	COG1070	Carbohydrate kinase
F3L01_RS14525	COG2329	Antibiotic biosynthesis monooxygenase
F3L01_RS14545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS14560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3L01_RS14565	COG4187	Peptidase family M20/M25/M40
F3L01_RS14570	COG1414	Transcriptional regulator
F3L01_RS14575	COG0833	amino acid
F3L01_RS14585	COG3239	Fatty acid desaturase
F3L01_RS14595	COG2720	vancomycin resistance protein
F3L01_RS14600	COG1785	Belongs to the alkaline phosphatase family
F3L01_RS14610	COG3655	Transcriptional regulator
F3L01_RS14630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS14635	COG0346	lactoylglutathione lyase activity
F3L01_RS14655	COG0714	Associated with various cellular activities
F3L01_RS14680	COG0463	Glycosyl transferase, family 2
F3L01_RS14715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3L01_RS14720	COG0753	catalase activity
F3L01_RS14760	COG0714	Associated with various cellular activities
F3L01_RS14855	COG0778	Nitroreductase
F3L01_RS14860	COG1846	Transcriptional regulator
F3L01_RS14880	COG4884	unkown
F3L01_RS14880	COG3831	ATPase activity
F3L01_RS14890	COG1136	(ABC) transporter
F3L01_RS14920	COG0456	acetyltransferase
F3L01_RS14940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS14955	COG0642	Histidine kinase
F3L01_RS14960	COG0745	RESPONSE REGULATOR receiver
F3L01_RS14965	COG0596	Alpha beta hydrolase
F3L01_RS14995	COG0730	response to heat
F3L01_RS15005	COG0833	amino acid
F3L01_RS15015	COG4335	DNA alkylation repair
F3L01_RS15080	COG1984	allophanate hydrolase subunit 2
F3L01_RS15085	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3L01_RS15090	COG1414	Transcriptional regulator
F3L01_RS15105	COG0640	Transcriptional regulator
F3L01_RS15115	COG1960	acyl-CoA dehydrogenase activity
F3L01_RS15150	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
F3L01_RS15175	COG3848	Pyruvate phosphate dikinase
F3L01_RS15175	COG0574	Belongs to the PEP-utilizing enzyme family
F3L01_RS15180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS15200	COG1063	alcohol dehydrogenase
F3L01_RS15210	COG1027	Aspartate ammonia-lyase
F3L01_RS15215	COG0252	asparaginase activity
F3L01_RS15220	COG1396	sequence-specific DNA binding
F3L01_RS15255	COG5002	protein histidine kinase activity
F3L01_RS15280	COG2207	Transcriptional regulator
F3L01_RS15300	COG0531	amino acid
F3L01_RS15305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3L01_RS15315	COG0531	amino acid
F3L01_RS15320	COG0697	spore germination
F3L01_RS15325	COG0784	Response regulator, receiver
F3L01_RS15330	COG4191	Histidine kinase
F3L01_RS15375	COG0737	Belongs to the 5'-nucleotidase family
F3L01_RS15385	COG1335	isochorismatase
F3L01_RS15405	COG0583	DNA-binding transcription factor activity
F3L01_RS15410	COG1846	Transcriptional regulator
F3L01_RS15415	COG0598	Magnesium transport protein CorA
F3L01_RS15435	COG1073	alpha beta
F3L01_RS15455	COG0415	Belongs to the DNA photolyase family
F3L01_RS15470	COG0288	reversible hydration of carbon dioxide
F3L01_RS15480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3L01_RS15485	COG5609	conserved protein (DUF2294)
F3L01_RS15495	COG0456	acetyltransferase
F3L01_RS15500	COG1575	Belongs to the MenA family. Type 1 subfamily
F3L01_RS15525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS15535	COG0798	PFAM Bile acid sodium symporter
F3L01_RS15540	COG0640	Transcriptional regulator
F3L01_RS15550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3L01_RS15555	COG3320	Male sterility
F3L01_RS15555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3L01_RS15560	COG1309	transcriptional regulator
F3L01_RS15565	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS15570	COG1522	sequence-specific DNA binding
F3L01_RS15595	COG0346	lactoylglutathione lyase activity
F3L01_RS15720	COG2814	Major facilitator Superfamily
F3L01_RS15740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F3L01_RS15750	COG1690	Belongs to the RtcB family
F3L01_RS15760	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
F3L01_RS15775	COG0577	efflux transmembrane transporter activity
F3L01_RS15795	COG3850	Histidine kinase
F3L01_RS15795	COG5002	protein histidine kinase activity
F3L01_RS15805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS15835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3L01_RS15855	COG0662	Cupin 2, conserved barrel domain protein
F3L01_RS15860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS15860	COG2207	Transcriptional regulator
F3L01_RS15880	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS15880	COG3409	Peptidoglycan-binding domain 1 protein
F3L01_RS16050	COG4282	regulation of fungal-type cell wall biogenesis
F3L01_RS16085	COG1876	peptidase activity
F3L01_RS16090	COG2843	Capsule synthesis protein
F3L01_RS16100	COG0477	Major facilitator Superfamily
F3L01_RS16115	COG1846	Transcriptional regulator
F3L01_RS16120	COG2814	Major facilitator Superfamily
F3L01_RS16130	COG2031	fatty acid transporter
F3L01_RS16140	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3L01_RS16195	COG1288	antiporter activity
F3L01_RS16200	COG2356	endonuclease I
F3L01_RS16225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3L01_RS16245	COG1733	regulation of RNA biosynthetic process
F3L01_RS16250	COG0778	Nitroreductase
F3L01_RS16280	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS16290	COG1131	(ABC) transporter
F3L01_RS16315	COG1011	Hydrolase
F3L01_RS16360	COG0628	permease
F3L01_RS16415	COG1253	flavin adenine dinucleotide binding
F3L01_RS16420	COG0789	Transcriptional regulator
F3L01_RS16430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3L01_RS16460	COG0697	spore germination
F3L01_RS16470	COG1357	PFAM Pentapeptide repeats (8 copies)
F3L01_RS16475	COG3813	Protein conserved in bacteria
F3L01_RS16480	COG2706	6-phosphogluconolactonase activity
F3L01_RS16485	COG1070	Carbohydrate kinase
F3L01_RS16500	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F3L01_RS16505	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3L01_RS16510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3L01_RS16515	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3L01_RS16520	COG0604	alcohol dehydrogenase
F3L01_RS16525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3L01_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS16555	COG0840	transmembrane signaling receptor activity
F3L01_RS16565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3L01_RS16565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3L01_RS16570	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3L01_RS16570	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3L01_RS16575	COG1733	regulation of RNA biosynthetic process
F3L01_RS16590	COG0656	L-ascorbic acid biosynthetic process
F3L01_RS16595	COG2814	Major facilitator Superfamily
F3L01_RS16620	COG0814	amino acid
F3L01_RS16650	COG1733	regulation of RNA biosynthetic process
F3L01_RS16655	COG2188	Transcriptional regulator
F3L01_RS16660	COG0673	inositol 2-dehydrogenase activity
F3L01_RS16665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3L01_RS16670	COG1733	regulation of RNA biosynthetic process
F3L01_RS16675	COG1733	regulation of RNA biosynthetic process
F3L01_RS16695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS16715	COG0384	phenazine biosynthesis protein PhzF
F3L01_RS16720	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS16725	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3L01_RS16730	COG1733	regulation of RNA biosynthetic process
F3L01_RS16750	COG0726	polysaccharide deacetylase
F3L01_RS16760	COG1191	sigma factor activity
F3L01_RS16770	COG1280	lysine exporter protein (LysE YggA)
F3L01_RS16830	COG1151	hydroxylamine reductase activity
F3L01_RS16840	COG3409	Peptidoglycan-binding domain 1 protein
F3L01_RS16840	COG3757	hydrolase, family 25
F3L01_RS16870	COG2072	flavoprotein involved in K transport
F3L01_RS16905	COG1113	amino acid transport
F3L01_RS16910	COG2814	Major facilitator Superfamily
F3L01_RS16940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3L01_RS16945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3L01_RS16960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS16965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS16970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS16975	COG3739	integral membrane protein
F3L01_RS17005	COG0583	DNA-binding transcription factor activity
F3L01_RS17025	COG1193	negative regulation of DNA recombination
F3L01_RS17040	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F3L01_RS17045	COG1164	Oligoendopeptidase f
F3L01_RS17050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3L01_RS17075	COG0584	glycerophosphoryl diester phosphodiesterase
F3L01_RS17085	COG0640	Transcriptional regulator
F3L01_RS17090	COG0604	alcohol dehydrogenase
F3L01_RS17100	COG0457	Tetratricopeptide repeat
F3L01_RS17110	COG2808	Putative FMN-binding domain
F3L01_RS17130	COG0277	FAD linked oxidase domain protein
F3L01_RS17155	COG1183	phosphatidylcholine synthase activity
F3L01_RS17160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS17160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS17165	COG1252	NADH dehydrogenase
F3L01_RS17175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3L01_RS17185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3L01_RS17195	COG0457	Tetratricopeptide repeat
F3L01_RS17275	COG3852	Histidine kinase
F3L01_RS17285	COG1285	pathogenesis
F3L01_RS17295	COG2514	catechol 2,3-dioxygenase activity
F3L01_RS17300	COG2720	vancomycin resistance protein
F3L01_RS17335	COG0716	FMN binding
F3L01_RS17345	COG0494	nUDIX hydrolase
F3L01_RS17365	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS17375	COG0165	Argininosuccinate lyase
F3L01_RS17390	COG4145	pantothenate transmembrane transporter activity
F3L01_RS17440	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS17450	COG1657	PFAM Prenyltransferase squalene oxidase
F3L01_RS17455	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
F3L01_RS17460	COG2962	Rard protein
F3L01_RS17465	COG3326	Membrane
F3L01_RS17480	COG0489	protein tyrosine kinase activity
F3L01_RS17490	COG0314	molybdopterin synthase activity
F3L01_RS17495	COG0303	'Molybdopterin
F3L01_RS17500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3L01_RS17505	COG2116	formate transmembrane transporter activity
F3L01_RS17515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3L01_RS17520	COG5609	conserved protein (DUF2294)
F3L01_RS17525	COG2427	Protein of unknown function (DUF1641)
F3L01_RS17530	COG3383	formate dehydrogenase (NAD+) activity
F3L01_RS17535	COG0697	spore germination
F3L01_RS17550	COG0531	amino acid
F3L01_RS17585	COG2226	methyltransferase
F3L01_RS17590	COG4166	transmembrane transport
F3L01_RS17595	COG4166	transmembrane transport
F3L01_RS17600	COG4166	transmembrane transport
F3L01_RS17610	COG1316	TRANSCRIPTIONal
F3L01_RS17620	COG1595	DNA-templated transcription, initiation
F3L01_RS17630	COG1131	(ABC) transporter
F3L01_RS17640	COG0673	inositol 2-dehydrogenase activity
F3L01_RS17645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3L01_RS17650	COG0187	DNA topoisomerase II activity
F3L01_RS17655	COG1832	CoA-binding protein
F3L01_RS17660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3L01_RS17665	COG0745	RESPONSE REGULATOR receiver
F3L01_RS17685	COG4841	protein insertion into membrane
F3L01_RS17690	COG0824	Thioesterase
F3L01_RS17725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3L01_RS17735	COG2274	protein secretion by the type I secretion system
F3L01_RS17740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3L01_RS17770	COG2211	Major facilitator Superfamily
F3L01_RS17780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3L01_RS17795	COG0183	Belongs to the thiolase family
F3L01_RS17800	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS17805	COG1268	BioY protein
F3L01_RS17810	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS17815	COG1396	sequence-specific DNA binding
F3L01_RS17855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS17865	COG5002	protein histidine kinase activity
F3L01_RS17870	COG0400	carboxylic ester hydrolase activity
F3L01_RS17880	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3L01_RS17885	COG0069	glutamate synthase activity
F3L01_RS17890	COG1902	pentaerythritol trinitrate reductase activity
F3L01_RS17895	COG1329	Transcriptional regulator
F3L01_RS17950	COG4846	Membrane protein involved in cytochrome C biogenesis
F3L01_RS17955	COG0785	Cytochrome C biogenesis protein
F3L01_RS17965	COG1473	amidohydrolase
F3L01_RS17975	COG1131	(ABC) transporter
F3L01_RS17990	COG0583	DNA-binding transcription factor activity
F3L01_RS18000	COG1346	cytolysis
F3L01_RS18015	COG0730	response to heat
F3L01_RS18040	COG1132	(ABC) transporter
F3L01_RS18045	COG1132	(ABC) transporter
F3L01_RS18080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3L01_RS18095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3L01_RS18115	COG1695	Transcriptional regulator
F3L01_RS18120	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS18140	COG0741	lytic transglycosylase activity
F3L01_RS18140	COG0739	heme binding
F3L01_RS18140	COG1196	nuclear chromosome segregation
F3L01_RS18145	COG0741	lytic transglycosylase activity
F3L01_RS18175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3L01_RS18220	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS18220	COG1388	LysM domain
F3L01_RS18220	COG3409	Peptidoglycan-binding domain 1 protein
F3L01_RS18225	COG4824	toxin secretion phage lysis holin
F3L01_RS18370	COG1595	DNA-templated transcription, initiation
F3L01_RS18480	COG1396	sequence-specific DNA binding
F3L01_RS18500	COG0174	glutamine synthetase
F3L01_RS18505	COG0789	Transcriptional regulator
F3L01_RS18510	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
F3L01_RS18515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3L01_RS18520	COG2860	membrane
F3L01_RS18530	COG0464	growth
F3L01_RS18560	COG3584	3D domain protein
F3L01_RS18560	COG1388	LysM domain
F3L01_RS18570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3L01_RS18570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3L01_RS18570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3L01_RS18575	COG1105	Belongs to the carbohydrate kinase PfkB family
F3L01_RS18580	COG1349	DNA-binding transcription factor activity
F3L01_RS18585	COG1979	alcohol dehydrogenase
F3L01_RS18590	COG2322	membrane
F3L01_RS18600	COG1113	amino acid transport
F3L01_RS18610	COG1408	metallophosphoesterase
F3L01_RS18615	COG2116	formate transmembrane transporter activity
F3L01_RS18630	COG2217	Heavy metal translocating P-type atpase
F3L01_RS18635	COG2608	mercury ion transmembrane transporter activity
F3L01_RS18640	COG1937	Protein conserved in bacteria
F3L01_RS18650	COG2819	hydrolase of the alpha beta superfamily
F3L01_RS18655	COG1120	ATPase activity
F3L01_RS18660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS18665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS18670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS18675	COG0708	Exodeoxyribonuclease III
F3L01_RS18680	COG2169	Transcriptional regulator
F3L01_RS18685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3L01_RS18690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F3L01_RS18710	COG2267	carboxylic ester hydrolase activity
F3L01_RS18715	COG3300	MHYT domain
F3L01_RS18715	COG5001	Diguanylate cyclase
F3L01_RS18735	COG1086	Polysaccharide biosynthesis protein
F3L01_RS18755	COG1346	cytolysis
F3L01_RS18765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3L01_RS18775	COG2188	Transcriptional regulator
F3L01_RS18780	COG2723	6-phospho-beta-galactosidase activity
F3L01_RS18790	COG1404	Belongs to the peptidase S8 family
F3L01_RS18795	COG3773	Cell wall hydrolase
F3L01_RS18805	COG1368	sulfuric ester hydrolase activity
F3L01_RS18810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F3L01_RS18835	COG4550	Control of competence regulator ComK, YlbF/YmcA
F3L01_RS18845	COG1013	pyruvate-flavodoxin oxidoreductase activity
F3L01_RS18850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F3L01_RS18850	COG0674	pyruvate-flavodoxin oxidoreductase activity
F3L01_RS18860	COG2359	stage V sporulation protein S
F3L01_RS18865	COG1692	metallophosphoesterase
F3L01_RS18885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3L01_RS18890	COG1426	Protein conserved in bacteria
F3L01_RS18905	COG0300	oxidoreductase activity
F3L01_RS18910	COG0612	Peptidase, M16
F3L01_RS18915	COG0612	Peptidase, M16
F3L01_RS18940	COG2188	Transcriptional regulator
F3L01_RS18945	COG1674	ftsk spoiiie
F3L01_RS18955	COG0740	serine-type endopeptidase activity
F3L01_RS18960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F3L01_RS18970	COG0527	aspartate kinase activity
F3L01_RS18975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3L01_RS18980	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3L01_RS18985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3L01_RS18990	COG1873	PFAM PRC-barrel domain
F3L01_RS18995	COG0612	Peptidase, M16
F3L01_RS19000	COG0726	polysaccharide deacetylase
F3L01_RS19015	COG0196	riboflavin kinase activity
F3L01_RS19025	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F3L01_RS19030	COG1550	Protein conserved in bacteria
F3L01_RS19040	COG1358	cellular component organization or biogenesis
F3L01_RS19045	COG2740	Nucleic-acid-binding protein implicated in transcription termination
F3L01_RS19050	COG0195	Participates in both transcription termination and antitermination
F3L01_RS19070	COG0750	zinc metalloprotease
F3L01_RS19080	COG4589	Belongs to the CDS family
F3L01_RS19125	COG4974	Belongs to the 'phage' integrase family
F3L01_RS19135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3L01_RS19140	COG0758	DNA mediated transformation
F3L01_RS19145	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3L01_RS19185	COG1837	Belongs to the UPF0109 family
F3L01_RS19195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3L01_RS19205	COG0552	protein localization to endoplasmic reticulum
F3L01_RS19210	COG1196	nuclear chromosome segregation
F3L01_RS19220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3L01_RS19225	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS19230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3L01_RS19245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3L01_RS19250	COG1461	Dihydroxyacetone kinase
F3L01_RS19255	COG1302	Protein conserved in bacteria
F3L01_RS19270	COG1564	THIamine pyrophosphokinase
F3L01_RS19275	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3L01_RS19285	COG2815	serine threonine protein kinase
F3L01_RS19285	COG0515	serine threonine protein kinase
F3L01_RS19290	COG0631	protein serine/threonine phosphatase activity
F3L01_RS19300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3L01_RS19300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3L01_RS19315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3L01_RS19320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3L01_RS19340	COG1561	YicC-like family, N-terminal region
F3L01_RS19360	COG0006	proline dipeptidase activity
F3L01_RS19380	COG3069	C4-dicarboxylate transmembrane transporter activity
F3L01_RS19445	COG0564	pseudouridine synthase activity
F3L01_RS19465	COG3599	regulation of cell shape
F3L01_RS19470	COG2302	S4 RNA-binding domain
F3L01_RS19475	COG0762	integral membrane protein
F3L01_RS19485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3L01_RS19495	COG1873	PFAM PRC-barrel domain
F3L01_RS19500	COG1191	sigma factor activity
F3L01_RS19505	COG1191	sigma factor activity
F3L01_RS19515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3L01_RS19520	COG0849	cell division
F3L01_RS19540	COG0772	Belongs to the SEDS family
F3L01_RS19560	COG0768	penicillin binding
F3L01_RS19585	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3L01_RS19600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F3L01_RS19605	COG1399	metal-binding, possibly nucleic acid-binding protein
F3L01_RS19640	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3L01_RS19640	COG1388	LysM domain
F3L01_RS19640	COG3409	Peptidoglycan-binding domain 1 protein
F3L01_RS19645	COG4824	toxin secretion phage lysis holin
F3L01_RS19715	COG0740	serine-type endopeptidase activity
F3L01_RS19725	COG4626	Terminase
F3L01_RS19725	COG1802	Transcriptional regulator
F3L01_RS19760	COG0582	viral genome integration into host DNA
F3L01_RS19820	COG2002	toxin-antitoxin pair type II binding
F3L01_RS19850	COG1396	sequence-specific DNA binding
F3L01_RS19865	COG1395	domain, Protein
F3L01_RS19885	COG0582	viral genome integration into host DNA
F3L01_RS19895	COG3480	Lon protease (S16) C-terminal proteolytic domain
F3L01_RS19900	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3L01_RS19905	COG3314	Sporulation integral membrane protein YlbJ
F3L01_RS19915	COG0742	ribosomal rna small subunit methyltransferase
F3L01_RS19930	COG3679	Belongs to the UPF0342 family
F3L01_RS19935	COG0406	alpha-ribazole phosphatase activity
F3L01_RS19950	COG2340	Cysteine-rich secretory protein family
F3L01_RS19965	COG3336	cytochrome c oxidase
F3L01_RS20000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F3L01_RS20005	COG0772	Belongs to the SEDS family
F3L01_RS20015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3L01_RS20020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F3L01_RS20030	COG4896	Protein conserved in bacteria
F3L01_RS20055	COG0483	inositol monophosphate 1-phosphatase activity
F3L01_RS20075	COG1982	Orn Lys Arg decarboxylase major
F3L01_RS20125	COG0022	dehydrogenase e1 component
F3L01_RS20130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3L01_RS20145	COG0561	phosphatase activity
F3L01_RS20155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F3L01_RS20160	COG0569	domain protein
F3L01_RS20180	COG0583	DNA-binding transcription factor activity
F3L01_RS20185	COG0517	IMP dehydrogenase activity
F3L01_RS20195	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
F3L01_RS20205	COG4703	Protein of unknown function (DUF1797)
F3L01_RS20220	COG2200	EAL domain
F3L01_RS20225	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS20230	COG1408	metallophosphoesterase
F3L01_RS20275	COG2814	Major facilitator Superfamily
F3L01_RS20295	COG3209	COG3209 Rhs family protein
F3L01_RS20315	COG2205	protein histidine kinase activity
F3L01_RS20325	COG0436	Aminotransferase
F3L01_RS20330	COG1609	Transcriptional regulator
F3L01_RS20335	COG3833	ABC-type maltose transport systems, permease component
F3L01_RS20340	COG1175	transmembrane transport
F3L01_RS20345	COG2182	Extracellular solute-binding protein
F3L01_RS20355	COG0366	Alpha amylase catalytic
F3L01_RS20360	COG3842	ATPase activity
F3L01_RS20400	COG0183	Belongs to the thiolase family
F3L01_RS20430	COG1695	Transcriptional regulator
F3L01_RS20435	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS20455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3L01_RS20460	COG0436	Aminotransferase
F3L01_RS20495	COG2084	Dehydrogenase
F3L01_RS20505	COG2199	diguanylate cyclase activity
F3L01_RS20505	COG2203	Gaf domain
F3L01_RS20510	COG0778	Nitroreductase
F3L01_RS20535	COG2190	(PTS) system
F3L01_RS20535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3L01_RS20535	COG1263	PTS System
F3L01_RS20540	COG3711	transcriptional antiterminator
F3L01_RS20550	COG2188	Transcriptional regulator
F3L01_RS20560	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3L01_RS20585	COG1547	Domain of unknown function (DUF309)
F3L01_RS20590	COG0456	acetyltransferase
F3L01_RS20595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F3L01_RS20600	COG4086	secreted protein
F3L01_RS20605	COG0561	phosphatase activity
F3L01_RS20610	COG0697	spore germination
F3L01_RS20625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3L01_RS20650	COG0733	neurotransmitter:sodium symporter activity
F3L01_RS20670	COG1686	Belongs to the peptidase S11 family
F3L01_RS20675	COG1725	Transcriptional regulator
F3L01_RS20680	COG1131	(ABC) transporter
F3L01_RS20700	COG1846	Transcriptional regulator
F3L01_RS20715	COG0598	Magnesium transport protein CorA
F3L01_RS20740	COG4974	Belongs to the 'phage' integrase family
F3L01_RS20750	COG0735	belongs to the Fur family
F3L01_RS20755	COG1300	Membrane
F3L01_RS20775	COG0667	Aldo Keto reductase
F3L01_RS20780	COG0656	L-ascorbic acid biosynthetic process
F3L01_RS20785	COG0456	acetyltransferase
F3L01_RS20785	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3L01_RS20795	COG0737	Belongs to the 5'-nucleotidase family
F3L01_RS20795	COG1525	nuclease
F3L01_RS20795	COG4085	toxin activity
F3L01_RS20805	COG0596	Alpha beta hydrolase
F3L01_RS20810	COG2056	Na+-H+ antiporter family
F3L01_RS20815	COG1609	Transcriptional regulator
F3L01_RS20820	COG0456	acetyltransferase
F3L01_RS20825	COG1073	alpha beta
F3L01_RS20840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3L01_RS20840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3L01_RS20845	COG0307	riboflavin synthase, alpha
F3L01_RS20875	COG1073	alpha beta
F3L01_RS20875	COG2226	methyltransferase
F3L01_RS20890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3L01_RS20905	COG0737	Belongs to the 5'-nucleotidase family
F3L01_RS20915	COG1522	sequence-specific DNA binding
F3L01_RS20960	COG0300	oxidoreductase activity
F3L01_RS20965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS20970	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3L01_RS20975	COG1760	l-serine dehydratase
F3L01_RS20980	COG1760	l-serine dehydratase
F3L01_RS21005	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3L01_RS21010	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS21025	COG1376	ErfK ybiS ycfS ynhG family protein
F3L01_RS21030	COG4129	membrane
F3L01_RS21035	COG1126	abc transporter atp-binding protein
F3L01_RS21040	COG0765	amino acid transport
F3L01_RS21045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3L01_RS21065	COG2323	membrane
F3L01_RS21070	COG0772	Belongs to the SEDS family
F3L01_RS21075	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3L01_RS21080	COG0022	dehydrogenase e1 component
F3L01_RS21085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3L01_RS21090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3L01_RS21105	COG0280	phosphate acetyltransferase
F3L01_RS21110	COG3829	transcription factor binding
F3L01_RS21110	COG3290	protein histidine kinase activity
F3L01_RS21120	COG0584	glycerophosphoryl diester phosphodiesterase
F3L01_RS21125	COG3093	addiction module antidote protein HigA
F3L01_RS21140	COG0750	zinc metalloprotease
F3L01_RS21145	COG0497	DNA recombination
F3L01_RS21155	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
F3L01_RS21165	COG0142	geranyltranstransferase activity
F3L01_RS21190	COG1302	Protein conserved in bacteria
F3L01_RS21195	COG0439	Biotin carboxylase
F3L01_RS21200	COG0511	ligase activity, forming carbon-carbon bonds
F3L01_RS21245	COG3854	ATPases associated with a variety of cellular activities
F3L01_RS21270	COG0006	proline dipeptidase activity
F3L01_RS21285	COG3872	metal-dependent enzyme
F3L01_RS21295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3L01_RS21330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS21340	COG1609	Transcriptional regulator
F3L01_RS21350	COG2076	Multidrug Resistance protein
F3L01_RS21355	COG2076	Multidrug Resistance protein
F3L01_RS21395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F3L01_RS21435	COG2169	Transcriptional regulator
F3L01_RS21470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3L01_RS21475	COG2169	Transcriptional regulator
F3L01_RS21500	COG2264	protein methyltransferase activity
F3L01_RS21550	COG1459	type II secretion system
F3L01_RS21555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3L01_RS21610	COG1410	methionine synthase
F3L01_RS21610	COG0646	methionine synthase
F3L01_RS21615	COG0646	methionine synthase
F3L01_RS21615	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3L01_RS21620	COG0626	cystathionine gamma-synthase activity
F3L01_RS21625	COG0626	cystathionine gamma-synthase activity
F3L01_RS21645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS21655	COG1940	carbohydrate kinase activity
F3L01_RS21660	COG4483	Protein conserved in bacteria
F3L01_RS21665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F3L01_RS21670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F3L01_RS21675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3L01_RS21680	COG0704	Plays a role in the regulation of phosphate uptake
F3L01_RS21690	COG0573	inorganic phosphate transmembrane transporter activity
F3L01_RS21695	COG0573	inorganic phosphate transmembrane transporter activity
F3L01_RS21700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3L01_RS21710	COG0477	Major facilitator Superfamily
F3L01_RS21715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3L01_RS21725	COG5521	maltodextrose utilization protein MalA
F3L01_RS21740	COG0735	belongs to the Fur family
F3L01_RS21745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3L01_RS21750	COG1121	(ABC) transporter
F3L01_RS21755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS21785	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F3L01_RS21790	COG2384	SAM-dependent methyltransferase
F3L01_RS21800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3L01_RS21805	COG0358	DNA primase activity
F3L01_RS21820	COG0517	IMP dehydrogenase activity
F3L01_RS21835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3L01_RS21840	COG0295	cytidine deaminase activity
F3L01_RS21845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F3L01_RS21855	COG1480	7TM receptor with intracellular HD hydrolase
F3L01_RS21860	COG1702	phosphate starvation-inducible protein PhoH
F3L01_RS21875	COG1610	YqeY-like protein
F3L01_RS21880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3L01_RS21885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3L01_RS21890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3L01_RS21920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3L01_RS21925	COG1733	regulation of RNA biosynthetic process
F3L01_RS21950	COG1466	dna polymerase III delta subunit
F3L01_RS21960	COG2333	competence protein COMEC
F3L01_RS21960	COG0658	competence protein
F3L01_RS21965	COG2131	deaminase
F3L01_RS21970	COG1596	polysaccharide export
F3L01_RS21970	COG1555	photosystem II stabilization
F3L01_RS21975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3L01_RS21980	COG2226	methyltransferase
F3L01_RS21985	COG0799	negative regulation of ribosome biogenesis
F3L01_RS21990	COG1713	HD superfamily hydrolase involved in NAD metabolism
F3L01_RS22000	COG1534	Rna-binding protein
F3L01_RS22010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F3L01_RS22015	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
F3L01_RS22050	COG0778	Nitroreductase
F3L01_RS22055	COG2357	RelA SpoT domain protein
F3L01_RS22065	COG1785	Belongs to the alkaline phosphatase family
F3L01_RS22075	COG2267	carboxylic ester hydrolase activity
F3L01_RS22115	COG1404	Belongs to the peptidase S8 family
F3L01_RS22120	COG3186	Phenylalanine-4-hydroxylase
F3L01_RS22130	COG2514	catechol 2,3-dioxygenase activity
F3L01_RS22135	COG2259	Doxx family
F3L01_RS22175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS22185	COG1012	belongs to the aldehyde dehydrogenase family
F3L01_RS22185	COG1454	alcohol dehydrogenase
F3L01_RS22190	COG0626	cystathionine gamma-synthase activity
F3L01_RS22195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3L01_RS22220	COG0768	penicillin binding
F3L01_RS22250	COG4122	O-methyltransferase activity
F3L01_RS22255	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3L01_RS22285	COG0628	permease
F3L01_RS22305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3L01_RS22320	COG1104	cysteine desulfurase activity
F3L01_RS22325	COG1959	2 iron, 2 sulfur cluster binding
F3L01_RS22330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3L01_RS22340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F3L01_RS22365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3L01_RS22375	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
F3L01_RS22375	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3L01_RS22380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3L01_RS22385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3L01_RS22385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3L01_RS22395	COG2244	polysaccharide biosynthetic process
F3L01_RS22400	COG2323	membrane
F3L01_RS22410	COG1862	Preprotein translocase
F3L01_RS22440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F3L01_RS22470	COG0157	Belongs to the NadC ModD family
F3L01_RS22475	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3L01_RS22480	COG1104	cysteine desulfurase activity
F3L01_RS22485	COG1827	regulation of RNA biosynthetic process
F3L01_RS22490	COG2258	MOSC domain
F3L01_RS22495	COG0077	Prephenate dehydratase
F3L01_RS22500	COG0577	efflux transmembrane transporter activity
F3L01_RS22505	COG0577	efflux transmembrane transporter activity
F3L01_RS22510	COG1136	(ABC) transporter
F3L01_RS22515	COG5002	protein histidine kinase activity
F3L01_RS22520	COG0745	RESPONSE REGULATOR receiver
F3L01_RS22530	COG3290	protein histidine kinase activity
F3L01_RS22540	COG2868	ribosomal protein
F3L01_RS22550	COG1530	ribonuclease E activity
F3L01_RS22555	COG1994	Peptidase M50
F3L01_RS22560	COG0739	heme binding
F3L01_RS22565	COG2894	cell division
F3L01_RS22585	COG1077	Cell shape determining protein MreB Mrl
F3L01_RS22605	COG0285	dihydrofolate synthase activity
F3L01_RS22620	COG1388	LysM domain
F3L01_RS22630	COG0113	porphobilinogen synthase activity
F3L01_RS22635	COG1587	Uroporphyrinogen-III synthase
F3L01_RS22645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3L01_RS22655	COG1846	Transcriptional regulator
F3L01_RS22660	COG1764	response to oxidative stress
F3L01_RS22675	COG0470	DNA polymerase III
F3L01_RS22675	COG1067	ATP-dependent peptidase activity
F3L01_RS22720	COG0622	Phosphoesterase
F3L01_RS22735	COG5401	PFAM Sporulation and spore germination
F3L01_RS22755	COG1309	transcriptional regulator
F3L01_RS22765	COG2197	response regulator
F3L01_RS22770	COG2233	PERMEase
F3L01_RS22775	COG0402	S-adenosylhomocysteine deaminase activity
F3L01_RS22780	COG1983	PspC domain protein
F3L01_RS22785	COG1396	sequence-specific DNA binding
F3L01_RS22790	COG0697	spore germination
F3L01_RS22800	COG1959	2 iron, 2 sulfur cluster binding
F3L01_RS22805	COG1668	transmembrane transport
F3L01_RS22810	COG4152	abc transporter atp-binding protein
F3L01_RS22815	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
F3L01_RS22820	COG1360	Flagellar Motor Protein
F3L01_RS22825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3L01_RS22830	COG1876	peptidase activity
F3L01_RS22835	COG0824	Thioesterase
F3L01_RS22840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3L01_RS22845	COG1053	succinate dehydrogenase
F3L01_RS22850	COG2009	succinate dehydrogenase
F3L01_RS22855	COG1719	4-vinyl reductase, 4VR
F3L01_RS22865	COG3118	belongs to the thioredoxin family
F3L01_RS22870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F3L01_RS22875	COG2086	electron transfer activity
F3L01_RS22880	COG1024	Enoyl-CoA hydratase
F3L01_RS22885	COG1309	transcriptional regulator
F3L01_RS22890	COG0318	PFAM AMP-dependent synthetase and ligase
F3L01_RS22920	COG2318	DinB family
F3L01_RS22945	COG1131	(ABC) transporter
F3L01_RS22950	COG2205	protein histidine kinase activity
F3L01_RS22955	COG0745	RESPONSE REGULATOR receiver
F3L01_RS22965	COG4895	conserved protein (DUF2196)
F3L01_RS22970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F3L01_RS22980	COG4509	Sortase family
F3L01_RS22985	COG1120	ATPase activity
F3L01_RS23000	COG5386	Cell surface protein
F3L01_RS23010	COG5386	Cell surface protein
F3L01_RS23015	COG1114	Component of the transport system for branched-chain amino acids
F3L01_RS23020	COG1187	pseudouridine synthase activity
F3L01_RS23030	COG1796	DNA polymerase
F3L01_RS23030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F3L01_RS23035	COG1286	toxin biosynthetic process
F3L01_RS23080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3L01_RS23090	COG1418	mRNA catabolic process
F3L01_RS23110	COG2814	Major facilitator Superfamily
F3L01_RS23115	COG1566	PFAM secretion protein HlyD family protein
F3L01_RS23120	COG1309	transcriptional regulator
F3L01_RS23125	COG1363	Peptidase, m42
F3L01_RS23150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F3L01_RS23170	COG1484	DNA-dependent DNA replication
F3L01_RS23175	COG3611	Membrane attachment protein
F3L01_RS23185	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F3L01_RS23190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3L01_RS23200	COG1971	Probably functions as a manganese efflux pump
F3L01_RS23210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3L01_RS23210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3L01_RS23215	COG5002	protein histidine kinase activity
F3L01_RS23220	COG0745	RESPONSE REGULATOR receiver
F3L01_RS23240	COG0538	isocitrate dehydrogenase activity
F3L01_RS23245	COG0372	Belongs to the citrate synthase family
F3L01_RS23255	COG0628	permease
F3L01_RS23260	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3L01_RS23285	COG1725	Transcriptional regulator
F3L01_RS23290	COG0281	malic enzyme
F3L01_RS23295	COG0587	DNA-directed DNA polymerase activity
F3L01_RS23310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F3L01_RS23325	COG4109	DRTGG domain
F3L01_RS23340	COG0006	proline dipeptidase activity
F3L01_RS23375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS23380	COG0662	Cupin 2, conserved barrel domain protein
F3L01_RS23395	COG1028	Short-chain dehydrogenase reductase Sdr
F3L01_RS23400	COG0589	response to stress
F3L01_RS23440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS23465	COG0827	DNA restriction-modification system
F3L01_RS23470	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F3L01_RS23475	COG3874	Sporulation protein YtfJ
F3L01_RS23490	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F3L01_RS23500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3L01_RS23515	COG1104	cysteine desulfurase activity
F3L01_RS23525	COG0583	DNA-binding transcription factor activity
F3L01_RS23530	COG0697	spore germination
F3L01_RS23535	COG1309	transcriptional regulator
F3L01_RS23540	COG1956	GAF domain-containing protein
F3L01_RS23545	COG0626	cystathionine gamma-synthase activity
F3L01_RS23615	COG0110	maltose O-acetyltransferase activity
F3L01_RS23620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3L01_RS23625	COG0454	-acetyltransferase
F3L01_RS23630	COG0517	IMP dehydrogenase activity
F3L01_RS23635	COG0123	including yeast histone deacetylase and acetoin utilization protein
F3L01_RS23650	COG0745	RESPONSE REGULATOR receiver
F3L01_RS23660	COG0666	response to abiotic stimulus
F3L01_RS23685	COG1609	Transcriptional regulator
F3L01_RS23690	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
F3L01_RS23690	COG1605	Chorismate mutase
F3L01_RS23695	COG4851	CamS sex pheromone cAM373 precursor
F3L01_RS23700	COG3118	belongs to the thioredoxin family
F3L01_RS23710	COG2309	aminopeptidase activity
F3L01_RS23735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS23765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3L01_RS23775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3L01_RS23780	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
F3L01_RS23785	COG1363	Peptidase, m42
F3L01_RS23795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS23810	COG0510	thiamine kinase activity
F3L01_RS23815	COG1523	belongs to the glycosyl hydrolase 13 family
F3L01_RS23825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3L01_RS23830	COG1349	DNA-binding transcription factor activity
F3L01_RS23835	COG1187	pseudouridine synthase activity
F3L01_RS23840	COG2244	polysaccharide biosynthetic process
F3L01_RS23845	COG2081	HI0933 family
F3L01_RS23850	COG2814	Major facilitator Superfamily
F3L01_RS23860	COG3832	glyoxalase III activity
F3L01_RS23880	COG1329	Transcriptional regulator
F3L01_RS23905	COG0314	molybdopterin synthase activity
F3L01_RS23910	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3L01_RS23915	COG0303	'Molybdopterin
F3L01_RS23925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F3L01_RS23930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3L01_RS23950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3L01_RS23960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3L01_RS24000	COG2814	Major facilitator Superfamily
F3L01_RS24005	COG0475	glutathione-regulated potassium exporter activity
F3L01_RS24010	COG0490	domain, Protein
F3L01_RS24015	COG0582	viral genome integration into host DNA
F3L01_RS24025	COG1136	(ABC) transporter
F3L01_RS24045	COG1242	4 iron, 4 sulfur cluster binding
F3L01_RS24050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F3L01_RS24065	COG1794	racemase activity, acting on amino acids and derivatives
F3L01_RS24085	COG2267	carboxylic ester hydrolase activity
F3L01_RS24090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3L01_RS24095	COG0671	phosphoesterase, PA-phosphatase related
F3L01_RS24100	COG0438	transferase activity, transferring glycosyl groups
F3L01_RS24120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS24165	COG5002	protein histidine kinase activity
F3L01_RS24170	COG3852	Histidine kinase
F3L01_RS24185	COG2267	carboxylic ester hydrolase activity
F3L01_RS24190	COG1368	sulfuric ester hydrolase activity
F3L01_RS24205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3L01_RS24210	COG1116	anion transmembrane transporter activity
F3L01_RS24215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3L01_RS24240	COG0494	nUDIX hydrolase
F3L01_RS24270	COG1854	S-ribosylhomocysteine lyase activity
F3L01_RS24280	COG0288	reversible hydration of carbon dioxide
F3L01_RS24285	COG1271	oxidase subunit
F3L01_RS24290	COG1294	oxidase, subunit
F3L01_RS24305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS24325	COG1842	Phage shock protein A
F3L01_RS24355	COG5002	protein histidine kinase activity
F3L01_RS24360	COG0745	RESPONSE REGULATOR receiver
F3L01_RS24390	COG1597	lipid kinase activity
F3L01_RS24430	COG0577	efflux transmembrane transporter activity
F3L01_RS24435	COG1136	(ABC) transporter
F3L01_RS24450	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS24460	COG0577	efflux transmembrane transporter activity
F3L01_RS24465	COG1136	(ABC) transporter
F3L01_RS24470	COG2207	Transcriptional regulator
F3L01_RS24470	COG3708	Transcriptional regulator
F3L01_RS24475	COG5658	integral membrane protein
F3L01_RS24480	COG0640	Transcriptional regulator
F3L01_RS24485	COG0745	RESPONSE REGULATOR receiver
F3L01_RS24490	COG2205	protein histidine kinase activity
F3L01_RS24495	COG0577	efflux transmembrane transporter activity
F3L01_RS24500	COG0577	efflux transmembrane transporter activity
F3L01_RS24505	COG1136	(ABC) transporter
F3L01_RS24510	COG0577	efflux transmembrane transporter activity
F3L01_RS24535	COG2188	Transcriptional regulator
F3L01_RS24555	COG3964	amidohydrolase
F3L01_RS24575	COG4948	Mandelate Racemase Muconate Lactonizing
F3L01_RS24585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F3L01_RS24590	COG0596	Alpha beta hydrolase
F3L01_RS24600	COG1169	isochorismate synthase
F3L01_RS24605	COG1575	Belongs to the MenA family. Type 1 subfamily
F3L01_RS24610	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3L01_RS24635	COG0058	SHG alpha-glucan phosphorylase activity
F3L01_RS24645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F3L01_RS24665	COG1404	Belongs to the peptidase S8 family
F3L01_RS24765	COG0544	peptidyl-prolyl cis-trans isomerase activity
F3L01_RS24800	COG1285	pathogenesis
F3L01_RS24805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3L01_RS24820	COG2155	Conserved Protein
F3L01_RS24825	COG1098	S1 RNA binding domain
F3L01_RS24830	COG0436	Aminotransferase
F3L01_RS24835	COG1522	sequence-specific DNA binding
F3L01_RS24840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3L01_RS24845	COG2267	carboxylic ester hydrolase activity
F3L01_RS24855	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F3L01_RS24875	COG5018	Exonuclease
F3L01_RS24880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3L01_RS24900	COG2050	protein possibly involved in aromatic compounds catabolism
F3L01_RS24910	COG1268	BioY protein
F3L01_RS24915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3L01_RS24920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3L01_RS24935	COG3584	3D domain protein
F3L01_RS24950	COG1252	NADH dehydrogenase
F3L01_RS24965	COG3708	Transcriptional regulator
F3L01_RS24980	COG1683	Conserved Protein
F3L01_RS25000	COG0316	Belongs to the HesB IscA family
F3L01_RS25015	COG1252	NADH dehydrogenase
F3L01_RS25025	COG2274	protein secretion by the type I secretion system
F3L01_RS25030	COG0390	transport system, permease component
F3L01_RS25035	COG2824	Alkylphosphonate utilization operon protein PhnA
F3L01_RS25080	COG4837	Protein of unknown function (DUF1462)
F3L01_RS25085	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F3L01_RS25095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3L01_RS25100	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F3L01_RS25120	COG1358	cellular component organization or biogenesis
F3L01_RS25130	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3L01_RS25140	COG0647	UMP catabolic process
F3L01_RS25150	COG2445	Protein of unknown function DUF86
F3L01_RS25155	COG1494	fructose-1,6-bisphosphatase
F3L01_RS25175	COG4470	Protein conserved in bacteria
F3L01_RS25185	COG0789	Transcriptional regulator
F3L01_RS25190	COG4377	Putative membrane peptidase family (DUF2324)
F3L01_RS25215	COG0739	heme binding
F3L01_RS25225	COG3377	Domain of unknown function (DUF1805)
F3L01_RS25230	COG0737	Belongs to the 5'-nucleotidase family
F3L01_RS25235	COG0719	Fe-S assembly protein
F3L01_RS25240	COG0822	iron-sulfur transferase activity
F3L01_RS25245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3L01_RS25250	COG0719	Fe-S assembly protein
F3L01_RS25255	COG0396	ATPase activity
F3L01_RS25260	COG1464	Belongs to the NlpA lipoprotein family
F3L01_RS25265	COG1464	Belongs to the NlpA lipoprotein family
F3L01_RS25270	COG2011	ABC-type metal ion transport system permease component
F3L01_RS25285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3L01_RS25290	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
F3L01_RS25300	COG1393	Belongs to the ArsC family
F3L01_RS25340	COG1309	transcriptional regulator
F3L01_RS25345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3L01_RS25350	COG1960	acyl-CoA dehydrogenase activity
F3L01_RS25355	COG0183	Belongs to the thiolase family
F3L01_RS25360	COG1024	Enoyl-CoA hydratase
F3L01_RS25360	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3L01_RS25370	COG1686	Belongs to the peptidase S11 family
F3L01_RS25385	COG0011	TIGRFAM Protein of
F3L01_RS25390	COG0840	transmembrane signaling receptor activity
F3L01_RS25405	COG2814	Major facilitator Superfamily
F3L01_RS25410	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F3L01_RS25420	COG0531	amino acid
F3L01_RS25450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3L01_RS25485	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS25495	COG1376	ErfK ybiS ycfS ynhG family protein
F3L01_RS25500	COG0745	RESPONSE REGULATOR receiver
F3L01_RS25505	COG5002	protein histidine kinase activity
F3L01_RS25540	COG0840	transmembrane signaling receptor activity
F3L01_RS25545	COG2151	metal-sulfur cluster biosynthetic enzyme
F3L01_RS25550	COG3227	Zinc metalloprotease (Elastase)
F3L01_RS25555	COG1741	Belongs to the pirin family
F3L01_RS25570	COG0586	Pfam SNARE associated Golgi protein
F3L01_RS25575	COG0475	glutathione-regulated potassium exporter activity
F3L01_RS25580	COG0490	domain, Protein
F3L01_RS25585	COG1115	amino acid carrier protein
F3L01_RS25590	COG0783	Belongs to the Dps family
F3L01_RS25605	COG1611	Belongs to the LOG family
F3L01_RS25615	COG1528	Iron-storage protein
F3L01_RS25625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS25630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS25635	COG1115	amino acid carrier protein
F3L01_RS25640	COG1115	amino acid carrier protein
F3L01_RS25645	COG2910	NAD(P)H-binding
F3L01_RS25660	COG0656	L-ascorbic acid biosynthetic process
F3L01_RS25665	COG2814	Major facilitator Superfamily
F3L01_RS25670	COG1733	regulation of RNA biosynthetic process
F3L01_RS25680	COG1252	NADH dehydrogenase
F3L01_RS25685	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F3L01_RS25725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3L01_RS25800	COG5002	protein histidine kinase activity
F3L01_RS25805	COG0745	RESPONSE REGULATOR receiver
F3L01_RS25810	COG1136	(ABC) transporter
F3L01_RS25815	COG0577	efflux transmembrane transporter activity
F3L01_RS25835	COG1136	(ABC) transporter
F3L01_RS25870	COG0557	exoribonuclease II activity
F3L01_RS25875	COG1647	Serine aminopeptidase, S33
F3L01_RS25880	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3L01_RS25885	COG1346	cytolysis
F3L01_RS25920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3L01_RS25935	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F3L01_RS26190	COG0582	viral genome integration into host DNA
F3L01_RS26215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3L01_RS26230	COG2323	membrane
F3L01_RS26240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3L01_RS26250	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F3L01_RS26260	COG1051	belongs to the nudix hydrolase family
F3L01_RS26270	COG0492	ferredoxin-NADP+ reductase activity
F3L01_RS26275	COG0457	Tetratricopeptide repeat
F3L01_RS26280	COG0110	maltose O-acetyltransferase activity
F3L01_RS26300	COG1950	PFAM Membrane protein of
F3L01_RS26305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3L01_RS26310	COG0556	nucleotide-excision repair
F3L01_RS26325	COG0789	Transcriptional regulator
F3L01_RS26345	COG0583	DNA-binding transcription factor activity
F3L01_RS26355	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3L01_RS26370	COG1132	(ABC) transporter
F3L01_RS26375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3L01_RS26380	COG3409	Peptidoglycan-binding domain 1 protein
F3L01_RS26380	COG0793	Belongs to the peptidase S41A family
F3L01_RS26385	COG2177	Part of the ABC transporter FtsEX involved in
F3L01_RS26390	COG2884	Cell division ATP-binding protein ftsE
F3L01_RS26415	COG1131	(ABC) transporter
F3L01_RS26445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3L01_RS26450	COG1278	Cold shock
F3L01_RS26455	COG1040	competence protein
F3L01_RS26460	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
F3L01_RS26465	COG0791	NLP P60 protein
F3L01_RS26470	COG1733	regulation of RNA biosynthetic process
F3L01_RS26475	COG1307	EDD domain protein, DegV family
F3L01_RS26480	COG1739	Uncharacterized protein family UPF0029
F3L01_RS26485	COG1316	TRANSCRIPTIONal
F3L01_RS26490	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F3L01_RS26495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3L01_RS26500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3L01_RS26510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
F3L01_RS26510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F3L01_RS26530	COG1486	melibiose metabolic process
F3L01_RS26535	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3L01_RS26540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3L01_RS26560	COG1447	Phosphotransferase system cellobiose-specific component IIA
F3L01_RS26570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F3L01_RS26575	COG1301	dicarboxylic acid transport
F3L01_RS26590	COG1511	domain protein
F3L01_RS26595	COG0583	DNA-binding transcription factor activity
F3L01_RS26600	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F3L01_RS26610	COG1271	oxidase subunit
F3L01_RS26615	COG1294	oxidase, subunit
F3L01_RS26620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F3L01_RS26630	COG1620	l-lactate permease
F3L01_RS26640	COG2389	metal-binding protein
F3L01_RS26650	COG1368	sulfuric ester hydrolase activity
F3L01_RS26660	COG1388	LysM domain
F3L01_RS26660	COG0791	NLP P60 protein
F3L01_RS26665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F3L01_RS26675	COG1215	transferase activity, transferring glycosyl groups
F3L01_RS26680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3L01_RS26685	COG3584	3D domain protein
F3L01_RS26685	COG1388	LysM domain
F3L01_RS26710	COG4715	Zinc finger, swim domain protein
F3L01_RS26715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F3L01_RS26755	COG0577	efflux transmembrane transporter activity
F3L01_RS26760	COG1136	(ABC) transporter
F3L01_RS26785	COG5002	protein histidine kinase activity
F3L01_RS26790	COG0745	RESPONSE REGULATOR receiver
F3L01_RS26795	COG1482	cell wall glycoprotein biosynthetic process
F3L01_RS26800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3L01_RS26800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3L01_RS26800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3L01_RS26805	COG3711	transcriptional antiterminator
F3L01_RS26805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3L01_RS26810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3L01_RS26825	COG1482	cell wall glycoprotein biosynthetic process
F3L01_RS26830	COG0662	Cupin 2, conserved barrel domain protein
F3L01_RS26830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3L01_RS26845	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3L01_RS26875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3L01_RS26880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3L01_RS26885	COG4464	protein tyrosine phosphatase activity
F3L01_RS26890	COG0489	protein tyrosine kinase activity
F3L01_RS26895	COG3944	biosynthesis protein
F3L01_RS26900	COG0489	protein tyrosine kinase activity
F3L01_RS26915	COG1609	Transcriptional regulator
F3L01_RS26925	COG0739	heme binding
F3L01_RS26940	COG3279	Response regulator of the LytR AlgR family
F3L01_RS26955	COG2385	sporulation resulting in formation of a cellular spore
F3L01_RS26970	COG4836	Membrane
F3L01_RS26975	COG1007	ATP synthesis coupled electron transport
F3L01_RS26980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3L01_RS26985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3L01_RS26995	COG0839	Belongs to the complex I subunit 6 family
F3L01_RS27015	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3L01_RS27030	COG5001	Diguanylate cyclase
F3L01_RS27030	COG3300	MHYT domain
F3L01_RS27080	COG0356	it plays a direct role in the translocation of protons across the membrane
F3L01_RS27115	COG0698	ribose 5-phosphate isomerase
F3L01_RS27130	COG2259	Doxx family
F3L01_RS27135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3L01_RS27150	COG0009	L-threonylcarbamoyladenylate synthase
F3L01_RS27185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3L01_RS27190	COG1494	fructose-1,6-bisphosphatase
F3L01_RS27210	COG4821	SIS domain
F3L01_RS27230	COG1960	acyl-CoA dehydrogenase activity
F3L01_RS27235	COG1960	acyl-CoA dehydrogenase activity
F3L01_RS27240	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3L01_RS27245	COG0183	Belongs to the thiolase family
F3L01_RS27250	COG0247	lactate metabolic process
F3L01_RS27250	COG2181	nitrate reductase activity
F3L01_RS27255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3L01_RS27265	COG3300	MHYT domain
F3L01_RS27265	COG5001	Diguanylate cyclase
F3L01_RS27280	COG3227	Zinc metalloprotease (Elastase)
F3L01_RS27285	COG2197	response regulator
F3L01_RS27290	COG4585	Histidine kinase
F3L01_RS27295	COG0842	Transport permease protein
F3L01_RS27300	COG1131	(ABC) transporter
F3L01_RS27305	COG0024	Methionine aminopeptidase
F3L01_RS27315	COG2234	aminopeptidase activity
F3L01_RS27335	COG1595	DNA-templated transcription, initiation
F3L01_RS27345	COG4506	Protein conserved in bacteria
F3L01_RS27350	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3L01_RS27375	COG2814	Major facilitator Superfamily
F3L01_RS27380	COG0789	Transcriptional regulator
F3L01_RS27385	COG0584	glycerophosphoryl diester phosphodiesterase
F3L01_RS27390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3L01_RS27400	COG1994	Peptidase M50
F3L01_RS27410	COG1078	dGTPase activity
F3L01_RS27415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3L01_RS27420	COG1120	ATPase activity
F3L01_RS27425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS27430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3L01_RS27450	COG0280	phosphate acetyltransferase
F3L01_RS27465	COG3773	Cell wall hydrolase
F3L01_RS27475	COG2363	Small membrane protein
F3L01_RS27485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3L01_RS27490	COG2233	PERMEase
F3L01_RS27495	COG0561	phosphatase activity
F3L01_RS27500	COG2814	Major facilitator Superfamily
F3L01_RS27510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F3L01_RS27515	COG1131	(ABC) transporter
F3L01_RS27520	COG2755	lipolytic protein G-D-S-L family
F3L01_RS27525	COG1609	Transcriptional regulator
F3L01_RS27535	COG0460	homoserine dehydrogenase
F3L01_RS27545	COG2873	o-acetylhomoserine
F3L01_RS27555	COG1011	Hydrolase
F3L01_RS27560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3L01_RS27570	COG2197	response regulator
F3L01_RS27575	COG4585	Histidine kinase
F3L01_RS27575	COG2203	Gaf domain
F3L01_RS27580	COG0351	phosphomethylpyrimidine kinase
F3L01_RS27585	COG3706	GGDEF domain
F3L01_RS27590	COG2879	small protein
F3L01_RS27595	COG1966	Carbon starvation protein
F3L01_RS27600	COG3279	Response regulator of the LytR AlgR family
F3L01_RS27605	COG0477	Major facilitator Superfamily
F3L01_RS27615	COG0438	transferase activity, transferring glycosyl groups
F3L01_RS27630	COG0840	transmembrane signaling receptor activity
F3L01_RS27640	COG1607	acyl-coa hydrolase
F3L01_RS27645	COG1216	Glycosyl transferase, family 2
F3L01_RS27660	COG1216	Glycosyl transferase, family 2
F3L01_RS27675	COG0463	Glycosyl transferase, family 2
F3L01_RS27680	COG0488	(ABC) transporter
F3L01_RS27685	COG1309	transcriptional regulator
F3L01_RS27690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3L01_RS27695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3L01_RS27695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3L01_RS27700	COG0628	permease
F3L01_RS27725	COG2814	Major facilitator Superfamily
F3L01_RS27730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3L01_RS27735	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
F3L01_RS27755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3L01_RS27760	COG1272	protein, Hemolysin III
F3L01_RS27780	COG1164	Oligoendopeptidase f
F3L01_RS27845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3L01_RS27850	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3L01_RS27855	COG4853	Protein conserved in bacteria
F3L01_RS27865	COG5002	protein histidine kinase activity
F3L01_RS27870	COG0745	RESPONSE REGULATOR receiver
F3L01_RS27900	COG0305	Participates in initiation and elongation during chromosome replication
F3L01_RS27910	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
F3L01_RS27915	COG4241	membrane
F3L01_RS27935	COG0012	GTP binding
F3L01_RS27940	COG4481	Protein conserved in bacteria
F3L01_RS27945	COG0668	transmembrane transport
F3L01_RS27955	COG1475	DNA binding
F3L01_RS27960	COG1192	Involved in chromosome partitioning
F3L01_RS27985	COG1847	R3H domain protein
F3L01_RS28000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F3L01_RS28100	COG1476	TRANSCRIPTIONal
F3L01_RS28105	COG2197	response regulator
F3L01_RS28115	COG1073	alpha beta
F3L01_RS28195	COG0484	heat shock protein binding
F3L01_RS28200	COG2918	glutathione biosynthetic process
F3L01_RS28200	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3L01_RS28210	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3L01_RS28220	COG1733	regulation of RNA biosynthetic process
F3L01_RS28235	COG0697	spore germination
F3L01_RS28260	COG2323	membrane
F3L01_RS28275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3L01_RS28360	COG0537	adenosine 5'-monophosphoramidase activity
F3L01_RS28385	COG3708	Transcriptional regulator
F3L01_RS28385	COG2207	Transcriptional regulator
F3L01_RS28430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3L01_RS28435	COG3209	COG3209 Rhs family protein
F3L01_RS28705	COG1923	regulation of RNA biosynthetic process
F3L01_RS28755	COG3209	COG3209 Rhs family protein
F3L01_RS28790	COG0582	viral genome integration into host DNA