locus-tag	class	description
L6483_RS00010	COG0592	DNA-directed DNA polymerase activity
L6483_RS00015	COG2501	S4 domain
L6483_RS00025	COG0187	DNA topoisomerase II activity
L6483_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L6483_RS00065	COG0516	GMP reductase activity
L6483_RS00065	COG0517	IMP dehydrogenase activity
L6483_RS00070	COG1686	Belongs to the peptidase S11 family
L6483_RS00100	COG1428	Deoxynucleoside kinase
L6483_RS00105	COG1428	Deoxynucleoside kinase
L6483_RS00110	COG1335	isochorismatase
L6483_RS00115	COG0590	tRNA wobble adenosine to inosine editing
L6483_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L6483_RS00180	COG1982	Orn Lys Arg decarboxylase major
L6483_RS00190	COG0470	DNA polymerase III
L6483_RS00195	COG1774	PSP1 C-terminal conserved region
L6483_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L6483_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L6483_RS00220	COG2002	toxin-antitoxin pair type II binding
L6483_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6483_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6483_RS00230	COG0084	hydrolase, TatD family'
L6483_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L6483_RS00250	COG4466	Protein conserved in bacteria
L6483_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L6483_RS00270	COG0251	oxidation-reduction process
L6483_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L6483_RS00305	COG2002	toxin-antitoxin pair type II binding
L6483_RS00310	COG2244	polysaccharide biosynthetic process
L6483_RS00315	COG3956	TIGRFAM MazG family protein
L6483_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L6483_RS00340	COG1098	S1 RNA binding domain
L6483_RS00355	COG2208	phosphoserine phosphatase activity
L6483_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L6483_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L6483_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6483_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L6483_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
L6483_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6483_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L6483_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L6483_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L6483_RS00420	COG1396	sequence-specific DNA binding
L6483_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L6483_RS00515	COG3880	PFAM UvrB UvrC protein
L6483_RS00525	COG0542	response to heat
L6483_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L6483_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
L6483_RS00560	COG1045	serine acetyltransferase
L6483_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L6483_RS00580	COG3688	RNA-binding protein containing a PIN domain
L6483_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L6483_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
L6483_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L6483_RS00625	COG2813	Specifically methylates the guanine in position
L6483_RS00640	COG1358	cellular component organization or biogenesis
L6483_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
L6483_RS00770	COG0201	protein transport
L6483_RS00780	COG0024	Methionine aminopeptidase
L6483_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L6483_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
L6483_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L6483_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6483_RS00855	COG0489	protein tyrosine kinase activity
L6483_RS00865	COG2194	sulfuric ester hydrolase activity
L6483_RS00870	COG0726	polysaccharide deacetylase
L6483_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L6483_RS00955	COG4856	YbbR-like protein
L6483_RS00975	COG0596	Alpha beta hydrolase
L6483_RS00995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L6483_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS01030	COG2011	ABC-type metal ion transport system permease component
L6483_RS01040	COG1464	Belongs to the NlpA lipoprotein family
L6483_RS01045	COG0604	alcohol dehydrogenase
L6483_RS01055	COG0277	FAD linked oxidase domain protein
L6483_RS01060	COG2271	Major facilitator Superfamily
L6483_RS01070	COG2814	Major facilitator Superfamily
L6483_RS01085	COG0601	transmembrane transport
L6483_RS01090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6483_RS01095	COG0444	Belongs to the ABC transporter superfamily
L6483_RS01100	COG4608	Belongs to the ABC transporter superfamily
L6483_RS01105	COG4166	transmembrane transport
L6483_RS01115	COG2207	Transcriptional regulator
L6483_RS01125	COG1309	transcriptional regulator
L6483_RS01135	COG4166	transmembrane transport
L6483_RS01140	COG4166	transmembrane transport
L6483_RS01145	COG0656	L-ascorbic acid biosynthetic process
L6483_RS01150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6483_RS01165	COG4149	molybdate abc transporter
L6483_RS01170	COG0725	ABC transporter, periplasmic molybdate-binding protein
L6483_RS01175	COG1910	domain protein
L6483_RS01190	COG0697	spore germination
L6483_RS01205	COG0204	Acyl-transferase
L6483_RS01215	COG1609	Transcriptional regulator
L6483_RS01225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS01235	COG0084	hydrolase, TatD family'
L6483_RS01245	COG5298	Protein conserved in bacteria
L6483_RS01270	COG0488	(ABC) transporter
L6483_RS01275	COG4585	Histidine kinase
L6483_RS01280	COG2197	response regulator
L6483_RS01285	COG1131	(ABC) transporter
L6483_RS01290	COG0842	Transport permease protein
L6483_RS01290	COG1511	domain protein
L6483_RS01295	COG0842	Transport permease protein
L6483_RS01310	COG0747	negative chemotaxis
L6483_RS01315	COG0601	transmembrane transport
L6483_RS01320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6483_RS01325	COG0444	Belongs to the ABC transporter superfamily
L6483_RS01330	COG4608	Belongs to the ABC transporter superfamily
L6483_RS01335	COG0561	phosphatase activity
L6483_RS01365	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L6483_RS01370	COG0179	Fumarylacetoacetate (FAA) hydrolase
L6483_RS01380	COG2814	Major facilitator Superfamily
L6483_RS01390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L6483_RS01400	COG4294	response to UV
L6483_RS01405	COG0457	Tetratricopeptide repeat
L6483_RS01405	COG0705	Rhomboid family
L6483_RS01415	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L6483_RS01420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L6483_RS01425	COG0864	Transcriptional regulator
L6483_RS01430	COG2337	Toxic component of a toxin-antitoxin (TA) module
L6483_RS01435	COG2183	response to ionizing radiation
L6483_RS01530	COG0802	atpase or kinase
L6483_RS01535	COG1214	PFAM Peptidase M22, glycoprotease
L6483_RS01540	COG0456	acetyltransferase
L6483_RS01550	COG0488	(ABC) transporter
L6483_RS01565	COG1266	CAAX protease self-immunity
L6483_RS01585	COG2252	PERMEase
L6483_RS01595	COG5002	protein histidine kinase activity
L6483_RS01620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L6483_RS01695	COG2205	protein histidine kinase activity
L6483_RS01700	COG0745	RESPONSE REGULATOR receiver
L6483_RS01720	COG0697	spore germination
L6483_RS01745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L6483_RS01750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L6483_RS01755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L6483_RS01765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L6483_RS01780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L6483_RS01790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L6483_RS01800	COG0151	Belongs to the GarS family
L6483_RS01825	COG0210	DNA helicase
L6483_RS01835	COG4851	CamS sex pheromone cAM373 precursor
L6483_RS01855	COG1335	isochorismatase
L6483_RS01860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L6483_RS01870	COG1464	Belongs to the NlpA lipoprotein family
L6483_RS01885	COG0003	Pfam Anion-transporting ATPase
L6483_RS01890	COG1846	Transcriptional regulator
L6483_RS01895	COG4682	membrane
L6483_RS01915	COG1597	lipid kinase activity
L6483_RS01920	COG0546	phosphoglycolate phosphatase activity
L6483_RS01925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L6483_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
L6483_RS01940	COG2076	Multidrug Resistance protein
L6483_RS01950	COG2309	aminopeptidase activity
L6483_RS01965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS01970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L6483_RS01975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L6483_RS01985	COG4807	Protein conserved in bacteria
L6483_RS02010	COG1757	Na H antiporter
L6483_RS02015	COG1473	amidohydrolase
L6483_RS02030	COG0450	alkyl hydroperoxide reductase
L6483_RS02050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS02055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS02060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6483_RS02075	COG0166	Belongs to the GPI family
L6483_RS02120	COG3541	Predicted nucleotidyltransferase
L6483_RS02130	COG0723	plastoquinol--plastocyanin reductase activity
L6483_RS02130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6483_RS02155	COG0765	amino acid transport
L6483_RS02160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6483_RS02170	COG0840	transmembrane signaling receptor activity
L6483_RS02175	COG0840	transmembrane signaling receptor activity
L6483_RS02200	COG0366	Alpha amylase catalytic
L6483_RS02205	COG1263	PTS System
L6483_RS02205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS02205	COG2190	(PTS) system
L6483_RS02235	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
L6483_RS02250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6483_RS02260	COG1116	anion transmembrane transporter activity
L6483_RS02265	COG0488	(ABC) transporter
L6483_RS02315	COG2270	Major facilitator Superfamily
L6483_RS02345	COG2310	stress, protein
L6483_RS02350	COG2310	stress, protein
L6483_RS02355	COG2310	stress, protein
L6483_RS02360	COG0861	Integral membrane protein TerC family
L6483_RS02370	COG3853	Toxic anion resistance protein (TelA)
L6483_RS02385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L6483_RS02395	COG1295	ribonuclease BN
L6483_RS02400	COG2217	Heavy metal translocating P-type atpase
L6483_RS02405	COG0697	spore germination
L6483_RS02415	COG0681	Belongs to the peptidase S26 family
L6483_RS02425	COG0586	Pfam SNARE associated Golgi protein
L6483_RS02440	COG3871	stress protein (general stress protein 26)
L6483_RS02445	COG0387	Pfam Sodium calcium exchanger
L6483_RS02455	COG0535	radical SAM domain protein
L6483_RS02475	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L6483_RS02480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L6483_RS02485	COG0101	tRNA pseudouridine synthase activity
L6483_RS02505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6483_RS02535	COG1263	PTS System
L6483_RS02535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS02540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6483_RS02560	COG0463	Glycosyl transferase, family 2
L6483_RS02570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L6483_RS02585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L6483_RS02605	COG1228	amidohydrolase
L6483_RS02610	COG1090	epimerase
L6483_RS02640	COG1988	membrane-bound metal-dependent
L6483_RS02645	COG1194	a g-specific adenine glycosylase
L6483_RS02670	COG1132	(ABC) transporter
L6483_RS02675	COG4129	membrane
L6483_RS02680	COG0067	glutamate synthase
L6483_RS02680	COG0069	glutamate synthase activity
L6483_RS02680	COG0070	glutamate synthase
L6483_RS02690	COG4555	ABC transporter
L6483_RS02710	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L6483_RS02715	COG0735	belongs to the Fur family
L6483_RS02830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
L6483_RS02835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L6483_RS02845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L6483_RS02855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L6483_RS02860	COG1716	ATPase activity
L6483_RS02860	COG5001	Diguanylate cyclase
L6483_RS02865	COG2766	serine protein kinase
L6483_RS02885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6483_RS02895	COG1585	Membrane protein implicated in regulation of membrane protease activity
L6483_RS02900	COG2268	Band 7 protein
L6483_RS02910	COG3290	protein histidine kinase activity
L6483_RS02915	COG4565	transcriptional regulatory protein
L6483_RS02920	COG2851	Citrate transporter
L6483_RS02940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L6483_RS02945	COG3842	ATPase activity
L6483_RS02950	COG1175	transmembrane transport
L6483_RS02955	COG0395	ABC-type sugar transport system, permease component
L6483_RS02970	COG0745	RESPONSE REGULATOR receiver
L6483_RS02975	COG5002	protein histidine kinase activity
L6483_RS02985	COG4990	cell redox homeostasis
L6483_RS02995	COG0697	spore germination
L6483_RS03000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS03010	COG5002	protein histidine kinase activity
L6483_RS03015	COG0745	RESPONSE REGULATOR receiver
L6483_RS03020	COG0454	-acetyltransferase
L6483_RS03020	COG0456	acetyltransferase
L6483_RS03025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L6483_RS03030	COG3383	formate dehydrogenase (NAD+) activity
L6483_RS03035	COG2427	Protein of unknown function (DUF1641)
L6483_RS03050	COG0531	amino acid
L6483_RS03055	COG0640	Transcriptional regulator
L6483_RS03060	COG2217	Heavy metal translocating P-type atpase
L6483_RS03065	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L6483_RS03080	COG3227	Zinc metalloprotease (Elastase)
L6483_RS03100	COG2720	vancomycin resistance protein
L6483_RS03105	COG1316	TRANSCRIPTIONal
L6483_RS03110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS03115	COG0346	lactoylglutathione lyase activity
L6483_RS03120	COG1253	flavin adenine dinucleotide binding
L6483_RS03125	COG1027	Aspartate ammonia-lyase
L6483_RS03130	COG1620	l-lactate permease
L6483_RS03145	COG3104	oligopeptide transport
L6483_RS03150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6483_RS03155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS03160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS03170	COG2226	methyltransferase
L6483_RS03175	COG0156	8-amino-7-oxononanoate synthase activity
L6483_RS03180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L6483_RS03185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L6483_RS03195	COG4548	von Willebrand factor, type A
L6483_RS03200	COG0714	Associated with various cellular activities
L6483_RS03205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6483_RS03220	COG0531	amino acid
L6483_RS03225	COG2188	Transcriptional regulator
L6483_RS03230	COG1263	PTS System
L6483_RS03230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS03235	COG0366	Alpha amylase catalytic
L6483_RS03250	COG0697	spore germination
L6483_RS03260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6483_RS03265	COG1115	amino acid carrier protein
L6483_RS03270	COG1126	abc transporter atp-binding protein
L6483_RS03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6483_RS03280	COG0765	amino acid transport
L6483_RS03285	COG0765	amino acid transport
L6483_RS03290	COG0833	amino acid
L6483_RS03315	COG2378	regulation of single-species biofilm formation
L6483_RS03320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L6483_RS03325	COG5002	protein histidine kinase activity
L6483_RS03340	COG0659	secondary active sulfate transmembrane transporter activity
L6483_RS03355	COG4166	transmembrane transport
L6483_RS03365	COG0601	transmembrane transport
L6483_RS03370	COG4608	Belongs to the ABC transporter superfamily
L6483_RS03380	COG2271	Major facilitator Superfamily
L6483_RS03385	COG1846	Transcriptional regulator
L6483_RS03390	COG0477	Major facilitator Superfamily
L6483_RS03395	COG1609	Transcriptional regulator
L6483_RS03400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L6483_RS03415	COG1172	Belongs to the binding-protein-dependent transport system permease family
L6483_RS03420	COG1879	ABC-type sugar transport system periplasmic component
L6483_RS03445	COG1063	alcohol dehydrogenase
L6483_RS03460	COG3568	Endonuclease Exonuclease Phosphatase
L6483_RS03490	COG0840	transmembrane signaling receptor activity
L6483_RS03495	COG3584	3D domain protein
L6483_RS03495	COG1388	LysM domain
L6483_RS03500	COG1476	TRANSCRIPTIONal
L6483_RS03515	COG3104	oligopeptide transport
L6483_RS03520	COG1114	Component of the transport system for branched-chain amino acids
L6483_RS03525	COG1464	Belongs to the NlpA lipoprotein family
L6483_RS03530	COG1960	acyl-CoA dehydrogenase activity
L6483_RS03535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L6483_RS03540	COG2011	ABC-type metal ion transport system permease component
L6483_RS03555	COG1113	amino acid transport
L6483_RS03560	COG2252	PERMEase
L6483_RS03575	COG2153	protein acetylation
L6483_RS03585	COG0475	glutathione-regulated potassium exporter activity
L6483_RS03585	COG0569	domain protein
L6483_RS03600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L6483_RS03605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L6483_RS03610	COG4990	cell redox homeostasis
L6483_RS03625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6483_RS03630	COG0697	spore germination
L6483_RS03635	COG0531	amino acid
L6483_RS03645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6483_RS03650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6483_RS03655	COG1918	ferrous iron import across plasma membrane
L6483_RS03655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L6483_RS03660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L6483_RS03665	COG0573	inorganic phosphate transmembrane transporter activity
L6483_RS03670	COG0581	inorganic phosphate transmembrane transporter activity
L6483_RS03675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L6483_RS03795	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
L6483_RS03815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L6483_RS03820	COG1116	anion transmembrane transporter activity
L6483_RS03825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6483_RS03830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6483_RS03835	COG0352	thiamine-phosphate diphosphorylase activity
L6483_RS03840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6483_RS03845	COG2104	thiamine diphosphate biosynthetic process
L6483_RS03855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6483_RS03860	COG0351	phosphomethylpyrimidine kinase
L6483_RS03900	COG2205	protein histidine kinase activity
L6483_RS03905	COG2814	Major facilitator Superfamily
L6483_RS03910	COG1846	Transcriptional regulator
L6483_RS03930	COG1136	(ABC) transporter
L6483_RS03940	COG2252	PERMEase
L6483_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS03965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6483_RS04005	COG0778	Nitroreductase
L6483_RS04010	COG2719	SpoVR family
L6483_RS04020	COG3591	Belongs to the peptidase S1B family
L6483_RS04030	COG0446	pyridine nucleotide-disulphide oxidoreductase
L6483_RS04035	COG1937	Protein conserved in bacteria
L6483_RS04040	COG0425	Belongs to the sulfur carrier protein TusA family
L6483_RS04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6483_RS04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS04045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6483_RS04050	COG0425	Belongs to the sulfur carrier protein TusA family
L6483_RS04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6483_RS04065	COG2210	Belongs to the sulfur carrier protein TusA family
L6483_RS04070	COG0730	response to heat
L6483_RS04085	COG0604	alcohol dehydrogenase
L6483_RS04090	COG1283	sodium-dependent phosphate transmembrane transporter activity
L6483_RS04105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6483_RS04105	COG3711	transcriptional antiterminator
L6483_RS04110	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6483_RS04115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6483_RS04135	COG3584	3D domain protein
L6483_RS04135	COG1388	LysM domain
L6483_RS04140	COG0577	efflux transmembrane transporter activity
L6483_RS04145	COG1136	(ABC) transporter
L6483_RS04155	COG5522	Integral membrane protein (intg_mem_TP0381)
L6483_RS04170	COG0577	efflux transmembrane transporter activity
L6483_RS04175	COG1114	Component of the transport system for branched-chain amino acids
L6483_RS04180	COG3546	catalase activity
L6483_RS04215	COG0586	Pfam SNARE associated Golgi protein
L6483_RS04250	COG0531	amino acid
L6483_RS04255	COG0475	glutathione-regulated potassium exporter activity
L6483_RS04265	COG1737	Transcriptional regulator
L6483_RS04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS04275	COG1263	PTS System
L6483_RS04285	COG2259	Doxx family
L6483_RS04300	COG1522	sequence-specific DNA binding
L6483_RS04315	COG2076	Multidrug Resistance protein
L6483_RS04320	COG1309	transcriptional regulator
L6483_RS04325	COG2814	Major facilitator Superfamily
L6483_RS04330	COG0657	acetylesterase activity
L6483_RS04340	COG2124	cytochrome p450
L6483_RS04350	COG1063	alcohol dehydrogenase
L6483_RS04355	COG4533	DNA binding
L6483_RS04360	COG2211	Major facilitator Superfamily
L6483_RS04370	COG0693	protein deglycase activity
L6483_RS04375	COG0753	catalase activity
L6483_RS04385	COG0531	amino acid
L6483_RS04390	COG1012	belongs to the aldehyde dehydrogenase family
L6483_RS04395	COG1132	(ABC) transporter
L6483_RS04400	COG1132	(ABC) transporter
L6483_RS04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6483_RS04410	COG0765	amino acid transport
L6483_RS04415	COG1126	abc transporter atp-binding protein
L6483_RS04430	COG0189	ligase activity
L6483_RS04460	COG0028	Belongs to the TPP enzyme family
L6483_RS04465	COG3527	Alpha-acetolactate decarboxylase
L6483_RS04475	COG0561	phosphatase activity
L6483_RS04480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L6483_RS04495	COG0659	secondary active sulfate transmembrane transporter activity
L6483_RS04515	COG2244	polysaccharide biosynthetic process
L6483_RS04530	COG4193	domain, Protein
L6483_RS04530	COG5263	repeat protein
L6483_RS04545	COG1024	Enoyl-CoA hydratase
L6483_RS04565	COG1363	Peptidase, m42
L6483_RS04695	COG1649	PFAM Uncharacterised BCR, COG1649
L6483_RS04730	COG0601	transmembrane transport
L6483_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6483_RS04740	COG0444	Belongs to the ABC transporter superfamily
L6483_RS04745	COG4608	Belongs to the ABC transporter superfamily
L6483_RS04775	COG0477	Major facilitator Superfamily
L6483_RS04780	COG3290	protein histidine kinase activity
L6483_RS04785	COG4565	transcriptional regulatory protein
L6483_RS04790	COG3181	Tripartite tricarboxylate transporter family receptor
L6483_RS04805	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
L6483_RS04840	COG4978	Transcriptional regulator
L6483_RS04840	COG0789	Transcriptional regulator
L6483_RS04885	COG0305	Participates in initiation and elongation during chromosome replication
L6483_RS04935	COG0477	Major facilitator Superfamily
L6483_RS05010	COG1404	Belongs to the peptidase S8 family
L6483_RS05075	COG3711	transcriptional antiterminator
L6483_RS05080	COG1263	PTS System
L6483_RS05080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS05080	COG2190	(PTS) system
L6483_RS05085	COG2723	6-phospho-beta-galactosidase activity
L6483_RS05105	COG0367	asparagine synthase
L6483_RS05120	COG1132	(ABC) transporter
L6483_RS05130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L6483_RS05130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L6483_RS05165	COG0577	efflux transmembrane transporter activity
L6483_RS05165	COG1136	(ABC) transporter
L6483_RS05190	COG1183	phosphatidylcholine synthase activity
L6483_RS05205	COG2376	Dihydroxyacetone kinase
L6483_RS05215	COG2376	Dihydroxyacetone kinase
L6483_RS05305	COG3237	CsbD-like
L6483_RS05330	COG1191	sigma factor activity
L6483_RS05340	COG2208	phosphoserine phosphatase activity
L6483_RS05345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L6483_RS05350	COG0784	Response regulator, receiver
L6483_RS05350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6483_RS05350	COG2205	protein histidine kinase activity
L6483_RS05350	COG2198	Histidine kinase
L6483_RS05390	COG2205	protein histidine kinase activity
L6483_RS05430	COG0420	3'-5' exonuclease activity
L6483_RS05435	COG4717	serine-type aminopeptidase activity
L6483_RS05450	COG0346	lactoylglutathione lyase activity
L6483_RS05455	COG0346	lactoylglutathione lyase activity
L6483_RS05470	COG2267	carboxylic ester hydrolase activity
L6483_RS05500	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L6483_RS05505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L6483_RS05515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L6483_RS05560	COG0477	Major facilitator Superfamily
L6483_RS05565	COG0477	Major facilitator Superfamily
L6483_RS05575	COG3973	AAA domain
L6483_RS05580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6483_RS05600	COG4980	gas vesicle protein
L6483_RS05605	COG0537	adenosine 5'-monophosphoramidase activity
L6483_RS05610	COG1131	(ABC) transporter
L6483_RS05615	COG4473	ABC transporter
L6483_RS05630	COG1309	transcriptional regulator
L6483_RS05640	COG3402	PFAM membrane-flanked domain
L6483_RS05645	COG3428	Bacterial PH domain
L6483_RS05675	COG3402	PFAM membrane-flanked domain
L6483_RS05680	COG3428	Bacterial PH domain
L6483_RS05685	COG2329	Antibiotic biosynthesis monooxygenase
L6483_RS05690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6483_RS05705	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L6483_RS05730	COG1309	transcriptional regulator
L6483_RS05735	COG1511	domain protein
L6483_RS05765	COG2378	regulation of single-species biofilm formation
L6483_RS05770	COG1609	Transcriptional regulator
L6483_RS05780	COG1234	tRNA 3'-trailer cleavage
L6483_RS05785	COG0095	Lipoate-protein ligase
L6483_RS05790	COG3328	transposase activity
L6483_RS05795	COG2205	protein histidine kinase activity
L6483_RS05800	COG0745	RESPONSE REGULATOR receiver
L6483_RS05825	COG0501	Belongs to the peptidase M48B family
L6483_RS05830	COG0697	spore germination
L6483_RS05850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L6483_RS05855	COG2224	Isocitrate lyase
L6483_RS05865	COG1278	Cold shock
L6483_RS05880	COG4903	ComK protein
L6483_RS05890	COG4585	Histidine kinase
L6483_RS05895	COG2197	response regulator
L6483_RS05905	COG0398	Pfam SNARE associated Golgi protein
L6483_RS05980	COG0179	Fumarylacetoacetate (FAA) hydrolase
L6483_RS06005	COG0367	asparagine synthase
L6483_RS06010	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
L6483_RS06015	COG0753	catalase activity
L6483_RS06025	COG0004	ammonium transporteR
L6483_RS06045	COG2996	Protein conserved in bacteria
L6483_RS06050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6483_RS06060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS06075	COG0561	phosphatase activity
L6483_RS06085	COG0542	response to heat
L6483_RS06095	COG2267	carboxylic ester hydrolase activity
L6483_RS06110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6483_RS06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L6483_RS06120	COG5504	Zn-dependent protease
L6483_RS06130	COG0180	Tryptophanyl-tRNA synthetase
L6483_RS06140	COG4166	transmembrane transport
L6483_RS06145	COG0601	transmembrane transport
L6483_RS06150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L6483_RS06155	COG0444	Belongs to the ABC transporter superfamily
L6483_RS06160	COG4608	Belongs to the ABC transporter superfamily
L6483_RS06165	COG0534	Mate efflux family protein
L6483_RS06170	COG4166	transmembrane transport
L6483_RS06185	COG0861	Integral membrane protein TerC family
L6483_RS06190	COG4862	establishment of competence for transformation
L6483_RS06195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6483_RS06205	COG1164	Oligoendopeptidase f
L6483_RS06220	COG2346	COG2346, Truncated hemoglobins
L6483_RS06225	COG4116	CYTH
L6483_RS06235	COG2357	RelA SpoT domain protein
L6483_RS06245	COG0564	pseudouridine synthase activity
L6483_RS06260	COG0772	Belongs to the SEDS family
L6483_RS06265	COG1216	Glycosyl transferase, family 2
L6483_RS06285	COG0463	Glycosyl transferase, family 2
L6483_RS06285	COG0457	Tetratricopeptide repeat
L6483_RS06305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L6483_RS06320	COG1091	dTDP-4-dehydrorhamnose reductase activity
L6483_RS06365	COG2153	protein acetylation
L6483_RS06375	COG2382	esterase
L6483_RS06390	COG5492	domain, Protein
L6483_RS06395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6483_RS06405	COG0512	Glutamine amidotransferase of anthranilate synthase
L6483_RS06405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L6483_RS06440	COG1620	l-lactate permease
L6483_RS06445	COG5634	Uncharacterized conserved protein (DUF2278)
L6483_RS06510	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6483_RS06520	COG1476	TRANSCRIPTIONal
L6483_RS06565	COG2226	methyltransferase
L6483_RS06575	COG1686	Belongs to the peptidase S11 family
L6483_RS06580	COG0681	Belongs to the peptidase S26 family
L6483_RS06600	COG1396	sequence-specific DNA binding
L6483_RS06615	COG1012	belongs to the aldehyde dehydrogenase family
L6483_RS06625	COG1176	ABC-type spermidine putrescine transport system, permease component I
L6483_RS06630	COG1177	transmembrane transport
L6483_RS06635	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
L6483_RS06645	COG2409	Drug exporters of the RND superfamily
L6483_RS06655	COG0564	pseudouridine synthase activity
L6483_RS06665	COG2340	Cysteine-rich secretory protein family
L6483_RS06670	COG0247	lactate metabolic process
L6483_RS06675	COG0277	FAD linked oxidase domain protein
L6483_RS06680	COG3835	regulator
L6483_RS06690	COG0745	RESPONSE REGULATOR receiver
L6483_RS06695	COG5002	protein histidine kinase activity
L6483_RS06700	COG2186	Transcriptional regulator
L6483_RS06720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L6483_RS06730	COG2116	formate transmembrane transporter activity
L6483_RS06735	COG0861	Integral membrane protein TerC family
L6483_RS06740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6483_RS06750	COG2030	dehydratase
L6483_RS06770	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS06775	COG3243	poly(R)-hydroxyalkanoic acid synthase
L6483_RS06780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6483_RS06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6483_RS06800	COG1840	ABC-type Fe3 transport system, periplasmic component
L6483_RS06805	COG3842	ATPase activity
L6483_RS06830	COG1349	DNA-binding transcription factor activity
L6483_RS06840	COG0235	Class ii aldolase
L6483_RS06850	COG2861	carbohydrate metabolic process
L6483_RS06860	COG3852	Histidine kinase
L6483_RS06875	COG2318	DinB family
L6483_RS06885	COG5002	protein histidine kinase activity
L6483_RS06895	COG0720	synthase
L6483_RS06910	COG4873	Protein conserved in bacteria
L6483_RS06940	COG1780	Probably involved in ribonucleotide reductase function
L6483_RS06950	COG1403	HNH endonuclease
L6483_RS06960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L6483_RS06965	COG1725	Transcriptional regulator
L6483_RS06970	COG1131	(ABC) transporter
L6483_RS06980	COG1131	(ABC) transporter
L6483_RS06985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6483_RS07000	COG1522	sequence-specific DNA binding
L6483_RS07010	COG1335	isochorismatase
L6483_RS07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6483_RS07025	COG2070	2-Nitropropane dioxygenase
L6483_RS07030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L6483_RS07040	COG1696	Membrane protein involved in D-alanine export
L6483_RS07065	COG0716	FMN binding
L6483_RS07080	COG3173	Aminoglycoside phosphotransferase
L6483_RS07100	COG0534	Mate efflux family protein
L6483_RS07105	COG1968	undecaprenyl-diphosphatase activity
L6483_RS07120	COG1846	Transcriptional regulator
L6483_RS07130	COG1301	dicarboxylic acid transport
L6483_RS07135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L6483_RS07140	COG4709	membrane
L6483_RS07145	COG3874	Sporulation protein YtfJ
L6483_RS07165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6483_RS07170	COG0028	Belongs to the TPP enzyme family
L6483_RS07175	COG0440	acetolactate synthase activity
L6483_RS07250	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L6483_RS07265	COG1183	phosphatidylcholine synthase activity
L6483_RS07270	COG1368	sulfuric ester hydrolase activity
L6483_RS07280	COG0019	diaminopimelate decarboxylase activity
L6483_RS07300	COG0529	Catalyzes the synthesis of activated sulfate
L6483_RS07305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L6483_RS07325	COG1648	precorrin-2 dehydrogenase activity
L6483_RS07330	COG0733	neurotransmitter:sodium symporter activity
L6483_RS07350	COG1757	Na H antiporter
L6483_RS07365	COG4758	membrane
L6483_RS07370	COG4585	Histidine kinase
L6483_RS07375	COG2197	response regulator
L6483_RS07385	COG1114	Component of the transport system for branched-chain amino acids
L6483_RS07395	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L6483_RS07435	COG0730	response to heat
L6483_RS07440	COG0306	phosphate transporter
L6483_RS07445	COG1392	Phosphate transport regulator
L6483_RS07450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6483_RS07465	COG3852	Histidine kinase
L6483_RS07470	COG1801	Protein of unknown function DUF72
L6483_RS07485	COG0582	viral genome integration into host DNA
L6483_RS07490	COG5002	protein histidine kinase activity
L6483_RS07510	COG0392	lysyltransferase activity
L6483_RS07510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L6483_RS07525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6483_RS07530	COG1686	Belongs to the peptidase S11 family
L6483_RS07535	COG2715	membrane protein required for spore maturation
L6483_RS07540	COG0700	Nucleoside recognition
L6483_RS07545	COG1187	pseudouridine synthase activity
L6483_RS07555	COG1333	cytochrome c biogenesis protein
L6483_RS07560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L6483_RS07565	COG0745	RESPONSE REGULATOR receiver
L6483_RS07570	COG5002	protein histidine kinase activity
L6483_RS07575	COG2096	Adenosyltransferase
L6483_RS07580	COG4942	peptidase
L6483_RS07590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L6483_RS07595	COG1141	Ferredoxin
L6483_RS07605	COG0514	ATP-dependent DNA helicase (RecQ)
L6483_RS07610	COG1266	CAAX protease self-immunity
L6483_RS07620	COG1408	metallophosphoesterase
L6483_RS07630	COG4862	establishment of competence for transformation
L6483_RS07635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L6483_RS07655	COG0492	ferredoxin-NADP+ reductase activity
L6483_RS07660	COG0252	asparaginase activity
L6483_RS07730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6483_RS07745	COG0142	geranyltranstransferase activity
L6483_RS07755	COG0142	geranyltranstransferase activity
L6483_RS07780	COG0457	Tetratricopeptide repeat
L6483_RS07800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L6483_RS07810	COG4347	Protein of unknown function (DUF1405)
L6483_RS07825	COG2738	Putative neutral zinc metallopeptidase
L6483_RS07835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS07840	COG1694	Mazg nucleotide pyrophosphohydrolase
L6483_RS07855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L6483_RS07860	COG0438	transferase activity, transferring glycosyl groups
L6483_RS07895	COG1199	ATP-dependent helicase activity
L6483_RS07895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L6483_RS07915	COG3935	DnaD domain protein
L6483_RS07920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L6483_RS07930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6483_RS07930	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6483_RS07990	COG0116	Belongs to the methyltransferase superfamily
L6483_RS08000	COG1199	ATP-dependent helicase activity
L6483_RS08005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L6483_RS08015	COG3173	Aminoglycoside phosphotransferase
L6483_RS08020	COG0024	Methionine aminopeptidase
L6483_RS08030	COG2233	PERMEase
L6483_RS08035	COG2311	Membrane
L6483_RS08040	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6483_RS08050	COG0456	acetyltransferase
L6483_RS08090	COG0754	glutathionylspermidine amidase activity
L6483_RS08105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6483_RS08120	COG0454	-acetyltransferase
L6483_RS08140	COG0328	RNA-DNA hybrid ribonuclease activity
L6483_RS08175	COG3403	YqcI/YcgG family
L6483_RS08180	COG1280	lysine exporter protein (LysE YggA)
L6483_RS08195	COG3162	membrane
L6483_RS08200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6483_RS08205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6483_RS08215	COG0475	glutathione-regulated potassium exporter activity
L6483_RS08220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6483_RS08225	COG0789	Transcriptional regulator
L6483_RS08225	COG4978	Transcriptional regulator
L6483_RS08235	COG2323	membrane
L6483_RS08240	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L6483_RS08275	COG2814	Major facilitator Superfamily
L6483_RS08305	COG1923	regulation of RNA biosynthetic process
L6483_RS08315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L6483_RS08320	COG1360	Flagellar Motor Protein
L6483_RS08325	COG2201	protein-glutamate methylesterase activity
L6483_RS08330	COG2198	Histidine kinase
L6483_RS08330	COG0643	Histidine kinase
L6483_RS08335	COG1776	CheC inhibitor of MCP methylation
L6483_RS08335	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6483_RS08350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L6483_RS08370	COG1256	bacterial-type flagellum assembly
L6483_RS08375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L6483_RS08380	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
L6483_RS08395	COG1815	bacterial-type flagellum-dependent cell motility
L6483_RS08400	COG1558	bacterial-type flagellum-dependent cell motility
L6483_RS08410	COG1766	The M ring may be actively involved in energy transduction
L6483_RS08415	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6483_RS08425	COG1157	protein secretion by the type III secretion system
L6483_RS08460	COG0835	chemotaxis
L6483_RS08460	COG0784	Response regulator, receiver
L6483_RS08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L6483_RS08480	COG0741	lytic transglycosylase activity
L6483_RS08490	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6483_RS08495	COG1776	CheC inhibitor of MCP methylation
L6483_RS08495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L6483_RS08505	COG1338	Plays a role in the flagellum-specific transport system
L6483_RS08510	COG1987	bacterial-type flagellum assembly
L6483_RS08520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L6483_RS08525	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L6483_RS08530	COG1419	protein localization to endoplasmic reticulum
L6483_RS08535	COG4786	Flagellar basal body rod
L6483_RS08540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L6483_RS08565	COG1309	transcriptional regulator
L6483_RS08585	COG2329	Antibiotic biosynthesis monooxygenase
L6483_RS08600	COG3764	Sortase (surface protein transpeptidase)
L6483_RS08605	COG3764	Sortase (surface protein transpeptidase)
L6483_RS08630	COG0583	DNA-binding transcription factor activity
L6483_RS08635	COG3842	ATPase activity
L6483_RS08640	COG0725	ABC transporter, periplasmic molybdate-binding protein
L6483_RS08650	COG1234	tRNA 3'-trailer cleavage
L6483_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS08680	COG0406	alpha-ribazole phosphatase activity
L6483_RS08700	COG1846	Transcriptional regulator
L6483_RS08710	COG0367	asparagine synthase
L6483_RS08740	COG1802	Transcriptional regulator
L6483_RS08745	COG0697	spore germination
L6483_RS08750	COG0523	cobalamin synthesis protein
L6483_RS08755	COG0701	Predicted permease
L6483_RS08770	COG1757	Na H antiporter
L6483_RS08775	COG0114	fumarate hydratase activity
L6483_RS08790	COG0534	Mate efflux family protein
L6483_RS08795	COG3340	Belongs to the peptidase S51 family
L6483_RS08815	COG0785	Cytochrome C biogenesis protein
L6483_RS08850	COG2733	membrane
L6483_RS08885	COG1131	(ABC) transporter
L6483_RS08900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6483_RS08925	COG0528	UMP kinase activity
L6483_RS08935	COG1027	Aspartate ammonia-lyase
L6483_RS08940	COG0281	malic enzyme
L6483_RS08945	COG4191	Histidine kinase
L6483_RS08950	COG0784	Response regulator, receiver
L6483_RS08960	COG1361	Conserved repeat domain
L6483_RS08965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6483_RS09020	COG2814	Major facilitator Superfamily
L6483_RS09035	COG1966	Carbon starvation protein
L6483_RS09045	COG1695	Transcriptional regulator
L6483_RS09055	COG0477	Major facilitator Superfamily
L6483_RS09060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6483_RS09065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L6483_RS09070	COG4166	transmembrane transport
L6483_RS09075	COG2223	nitrite transmembrane transporter activity
L6483_RS09080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6483_RS09095	COG2244	polysaccharide biosynthetic process
L6483_RS09100	COG0733	neurotransmitter:sodium symporter activity
L6483_RS09110	COG5566	PFAM Mor transcription activator
L6483_RS09115	COG2323	membrane
L6483_RS09130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6483_RS09140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6483_RS09145	COG0028	Belongs to the TPP enzyme family
L6483_RS09155	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
L6483_RS09165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L6483_RS09190	COG2814	Major facilitator Superfamily
L6483_RS09195	COG3384	dioxygenase
L6483_RS09205	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L6483_RS09215	COG0427	acetyl-CoA hydrolase
L6483_RS09235	COG1073	alpha beta
L6483_RS09240	COG4166	transmembrane transport
L6483_RS09265	COG0535	radical SAM domain protein
L6483_RS09270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS09295	COG1914	H( )-stimulated, divalent metal cation uptake system
L6483_RS09310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L6483_RS09315	COG0531	amino acid
L6483_RS09350	COG0714	Associated with various cellular activities
L6483_RS09360	COG3552	Protein containing von Willebrand factor type A (VWA) domain
L6483_RS09385	COG2390	Transcriptional regulator
L6483_RS09395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS09400	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L6483_RS09430	COG0006	proline dipeptidase activity
L6483_RS09435	COG2132	Multicopper oxidase
L6483_RS09450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L6483_RS09480	COG1114	Component of the transport system for branched-chain amino acids
L6483_RS09490	COG1276	copper resistance
L6483_RS09490	COG2372	response to copper ion
L6483_RS09495	COG4549	nuclear export factor GLE1
L6483_RS09505	COG0697	spore germination
L6483_RS09510	COG0583	DNA-binding transcription factor activity
L6483_RS09515	COG1959	2 iron, 2 sulfur cluster binding
L6483_RS09520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L6483_RS09525	COG0778	Nitroreductase
L6483_RS09535	COG0628	permease
L6483_RS09545	COG1231	oxidoreductase activity
L6483_RS09550	COG0523	cobalamin synthesis protein
L6483_RS09560	COG0318	PFAM AMP-dependent synthetase and ligase
L6483_RS09565	COG2030	dehydratase
L6483_RS09570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6483_RS09580	COG0411	ABC transporter
L6483_RS09600	COG0583	DNA-binding transcription factor activity
L6483_RS09630	COG1271	oxidase subunit
L6483_RS09635	COG1294	oxidase, subunit
L6483_RS09640	COG4988	ABC transporter
L6483_RS09645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L6483_RS09665	COG1686	Belongs to the peptidase S11 family
L6483_RS09680	COG0791	NLP P60 protein
L6483_RS09680	COG1388	LysM domain
L6483_RS09690	COG1132	(ABC) transporter
L6483_RS09695	COG0745	RESPONSE REGULATOR receiver
L6483_RS09700	COG5002	protein histidine kinase activity
L6483_RS09705	COG2205	protein histidine kinase activity
L6483_RS09710	COG0745	RESPONSE REGULATOR receiver
L6483_RS09735	COG0300	oxidoreductase activity
L6483_RS09740	COG4122	O-methyltransferase activity
L6483_RS09755	COG5658	integral membrane protein
L6483_RS09770	COG0460	homoserine dehydrogenase
L6483_RS09795	COG1316	TRANSCRIPTIONal
L6483_RS09805	COG0745	RESPONSE REGULATOR receiver
L6483_RS09810	COG5002	protein histidine kinase activity
L6483_RS09825	COG1285	pathogenesis
L6483_RS09830	COG1247	-acetyltransferase
L6483_RS09850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6483_RS09860	COG1082	Xylose isomerase domain protein TIM barrel
L6483_RS09870	COG2814	Major facilitator Superfamily
L6483_RS09875	COG1279	arginine transmembrane transporter activity
L6483_RS09885	COG1752	Esterase of the alpha-beta hydrolase superfamily
L6483_RS09920	COG0577	efflux transmembrane transporter activity
L6483_RS09925	COG2002	toxin-antitoxin pair type II binding
L6483_RS09930	COG1404	Belongs to the peptidase S8 family
L6483_RS09935	COG0640	Transcriptional regulator
L6483_RS09940	COG0667	Aldo Keto reductase
L6483_RS09945	COG2814	Major facilitator Superfamily
L6483_RS09970	COG0840	transmembrane signaling receptor activity
L6483_RS09985	COG3949	Membrane
L6483_RS09990	COG0783	Belongs to the Dps family
L6483_RS10005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6483_RS10015	COG1231	oxidoreductase activity
L6483_RS10025	COG4989	oxidoreductase activity
L6483_RS10030	COG0523	cobalamin synthesis protein
L6483_RS10035	COG0456	acetyltransferase
L6483_RS10040	COG0803	Belongs to the bacterial solute-binding protein 9 family
L6483_RS10040	COG3443	Belongs to the bacterial solute-binding protein 9 family
L6483_RS10050	COG0702	epimerase
L6483_RS10060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L6483_RS10070	COG4166	transmembrane transport
L6483_RS10085	COG0406	alpha-ribazole phosphatase activity
L6483_RS10095	COG5337	Spore coat protein CotH
L6483_RS10100	COG1051	belongs to the nudix hydrolase family
L6483_RS10105	COG0586	Pfam SNARE associated Golgi protein
L6483_RS10110	COG2244	polysaccharide biosynthetic process
L6483_RS10120	COG0701	Predicted permease
L6483_RS10125	COG3689	TIGRFAM TIGR03943 family protein
L6483_RS10130	COG1607	acyl-coa hydrolase
L6483_RS10140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6483_RS10155	COG0702	epimerase
L6483_RS10160	COG2839	Protein conserved in bacteria
L6483_RS10165	COG1253	flavin adenine dinucleotide binding
L6483_RS10180	COG1114	Component of the transport system for branched-chain amino acids
L6483_RS10185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6483_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6483_RS10215	COG1876	peptidase activity
L6483_RS10225	COG0154	amidase activity
L6483_RS10230	COG2211	Major facilitator Superfamily
L6483_RS10245	COG2368	4-hydroxyphenylacetate
L6483_RS10255	COG0196	riboflavin kinase activity
L6483_RS10270	COG0251	oxidation-reduction process
L6483_RS10280	COG3971	2-oxopent-4-enoate hydratase activity
L6483_RS10300	COG1942	4-Oxalocrotonate Tautomerase
L6483_RS10320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L6483_RS10325	COG4106	trans-aconitate 2-methyltransferase activity
L6483_RS10340	COG1819	glycosyl
L6483_RS10345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS10350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS10380	COG0456	acetyltransferase
L6483_RS10420	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6483_RS10520	COG3874	Sporulation protein YtfJ
L6483_RS10545	COG2226	methyltransferase
L6483_RS10570	COG0346	lactoylglutathione lyase activity
L6483_RS10580	COG0604	alcohol dehydrogenase
L6483_RS10585	COG1595	DNA-templated transcription, initiation
L6483_RS10615	COG0386	Belongs to the glutathione peroxidase family
L6483_RS10620	COG1305	Transglutaminase-like
L6483_RS10625	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L6483_RS10630	COG0714	Associated with various cellular activities
L6483_RS10645	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
L6483_RS10650	COG1140	nitrate reductase beta subunit
L6483_RS10655	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L6483_RS10660	COG2181	nitrate reductase activity
L6483_RS10665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L6483_RS10670	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L6483_RS10675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6483_RS10680	COG0303	'Molybdopterin
L6483_RS10685	COG0314	molybdopterin synthase activity
L6483_RS10695	COG2223	nitrite transmembrane transporter activity
L6483_RS10705	COG1648	precorrin-2 dehydrogenase activity
L6483_RS10715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L6483_RS10715	COG1587	Uroporphyrinogen-III synthase
L6483_RS10720	COG2146	nitrite reductase [NAD(P)H] activity
L6483_RS10725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L6483_RS10730	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L6483_RS10765	COG2359	stage V sporulation protein S
L6483_RS10790	COG1418	mRNA catabolic process
L6483_RS10795	COG0488	(ABC) transporter
L6483_RS10810	COG0629	single-stranded DNA binding
L6483_RS10825	COG1413	lyase activity
L6483_RS10840	COG2136	Putative SAM-dependent methyltransferase
L6483_RS10840	COG2521	methyltransferase
L6483_RS10890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L6483_RS10895	COG0017	Asparaginyl-tRNA synthetase
L6483_RS10900	COG1929	Belongs to the glycerate kinase type-1 family
L6483_RS10905	COG0471	metal ion transport
L6483_RS10910	COG0745	RESPONSE REGULATOR receiver
L6483_RS10930	COG0733	neurotransmitter:sodium symporter activity
L6483_RS10955	COG2610	gluconate transmembrane transporter activity
L6483_RS10960	COG1454	alcohol dehydrogenase
L6483_RS10965	COG1794	racemase activity, acting on amino acids and derivatives
L6483_RS10975	COG0456	acetyltransferase
L6483_RS10980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L6483_RS10990	COG1131	(ABC) transporter
L6483_RS10995	COG4473	ABC transporter
L6483_RS11005	COG0546	phosphoglycolate phosphatase activity
L6483_RS11025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6483_RS11030	COG3250	beta-galactosidase activity
L6483_RS11045	COG0768	penicillin binding
L6483_RS11055	COG0204	Acyl-transferase
L6483_RS11060	COG1272	protein, Hemolysin III
L6483_RS11070	COG0805	protein transport
L6483_RS11080	COG1307	EDD domain protein, DegV family
L6483_RS11090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L6483_RS11095	COG1999	signal sequence binding
L6483_RS11100	COG0071	Belongs to the small heat shock protein (HSP20) family
L6483_RS11105	COG0367	asparagine synthase
L6483_RS11125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6483_RS11130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L6483_RS11150	COG1335	isochorismatase
L6483_RS11155	COG0071	Belongs to the small heat shock protein (HSP20) family
L6483_RS11160	COG0668	transmembrane transport
L6483_RS11165	COG2203	Gaf domain
L6483_RS11165	COG4585	Histidine kinase
L6483_RS11170	COG2197	response regulator
L6483_RS11180	COG1064	alcohol dehydrogenase
L6483_RS11235	COG1125	glycine betaine transport
L6483_RS11235	COG0517	IMP dehydrogenase activity
L6483_RS11240	COG1174	glycine betaine transport
L6483_RS11280	COG1253	flavin adenine dinucleotide binding
L6483_RS11285	COG1012	belongs to the aldehyde dehydrogenase family
L6483_RS11290	COG5506	Protein of unknown function (DUF1694)
L6483_RS11305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6483_RS11310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L6483_RS11315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L6483_RS11320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6483_RS11325	COG0456	acetyltransferase
L6483_RS11330	COG3829	transcription factor binding
L6483_RS11335	COG1509	lysine 2,3-aminomutase activity
L6483_RS11370	COG4991	sh3 domain protein
L6483_RS11370	COG3064	Membrane
L6483_RS11370	COG0515	serine threonine protein kinase
L6483_RS11375	COG4326	sporulation control protein
L6483_RS11380	COG0671	phosphoesterase, PA-phosphatase related
L6483_RS11405	COG0456	acetyltransferase
L6483_RS11405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6483_RS11425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L6483_RS11430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6483_RS11475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L6483_RS11505	COG0300	oxidoreductase activity
L6483_RS11525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6483_RS11525	COG4499	WXG100 protein secretion system (Wss), protein YukC
L6483_RS11540	COG4841	protein insertion into membrane
L6483_RS11545	COG0372	Belongs to the citrate synthase family
L6483_RS11550	COG2079	MmgE PrpD family protein
L6483_RS11555	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L6483_RS11560	COG1960	acyl-CoA dehydrogenase activity
L6483_RS11575	COG1280	lysine exporter protein (LysE YggA)
L6483_RS11580	COG1024	Enoyl-CoA hydratase
L6483_RS11595	COG0420	3'-5' exonuclease activity
L6483_RS11620	COG2223	nitrite transmembrane transporter activity
L6483_RS11625	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS11630	COG1169	isochorismate synthase
L6483_RS11635	COG1021	2,3-dihydroxybenzoate-AMP ligase
L6483_RS11640	COG1535	isochorismatase
L6483_RS11640	COG3433	isochorismatase activity
L6483_RS11645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L6483_RS11650	COG3251	PFAM MbtH domain protein
L6483_RS11655	COG2814	Major facilitator Superfamily
L6483_RS11670	COG0776	regulation of translation
L6483_RS11680	COG2318	DinB family
L6483_RS11690	COG1115	amino acid carrier protein
L6483_RS11705	COG2329	Antibiotic biosynthesis monooxygenase
L6483_RS11710	COG1187	pseudouridine synthase activity
L6483_RS11715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L6483_RS11720	COG1136	(ABC) transporter
L6483_RS11735	COG2814	Major facilitator Superfamily
L6483_RS11795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS11830	COG1247	-acetyltransferase
L6483_RS11860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L6483_RS11870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS11880	COG1278	Cold shock
L6483_RS11895	COG0010	Belongs to the arginase family
L6483_RS11905	COG1846	Transcriptional regulator
L6483_RS11910	COG2814	Major facilitator Superfamily
L6483_RS11915	COG0583	DNA-binding transcription factor activity
L6483_RS11920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L6483_RS11935	COG0583	DNA-binding transcription factor activity
L6483_RS11940	COG2258	MOSC domain
L6483_RS11955	COG1132	(ABC) transporter
L6483_RS11960	COG1132	(ABC) transporter
L6483_RS11980	COG1396	sequence-specific DNA binding
L6483_RS12010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L6483_RS12020	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
L6483_RS12025	COG1595	DNA-templated transcription, initiation
L6483_RS12050	COG1649	PFAM Uncharacterised BCR, COG1649
L6483_RS12075	COG2971	BadF BadG BcrA BcrD
L6483_RS12085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L6483_RS12135	COG1309	transcriptional regulator
L6483_RS12150	COG0577	efflux transmembrane transporter activity
L6483_RS12150	COG1136	(ABC) transporter
L6483_RS12200	COG1846	Transcriptional regulator
L6483_RS12230	COG2195	Cleaves the N-terminal amino acid of tripeptides
L6483_RS12240	COG0110	maltose O-acetyltransferase activity
L6483_RS12245	COG1686	Belongs to the peptidase S11 family
L6483_RS12255	COG0768	penicillin binding
L6483_RS12260	COG1595	DNA-templated transcription, initiation
L6483_RS12270	COG0768	penicillin binding
L6483_RS12275	COG0768	penicillin binding
L6483_RS12280	COG2367	Beta-lactamase
L6483_RS12295	COG1131	(ABC) transporter
L6483_RS12305	COG1309	transcriptional regulator
L6483_RS12320	COG1960	acyl-CoA dehydrogenase activity
L6483_RS12325	COG0439	Biotin carboxylase
L6483_RS12330	COG0511	ligase activity, forming carbon-carbon bonds
L6483_RS12335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L6483_RS12340	COG1024	Enoyl-CoA hydratase
L6483_RS12345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L6483_RS12350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6483_RS12360	COG1247	-acetyltransferase
L6483_RS12365	COG0572	uridine kinase
L6483_RS12375	COG1686	Belongs to the peptidase S11 family
L6483_RS12400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L6483_RS12420	COG3227	Zinc metalloprotease (Elastase)
L6483_RS12435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L6483_RS12465	COG2814	Major facilitator Superfamily
L6483_RS12475	COG2226	methyltransferase
L6483_RS12510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS12555	COG3386	PFAM SMP-30 Gluconolaconase
L6483_RS12565	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L6483_RS12570	COG3773	Cell wall hydrolase
L6483_RS12580	COG0745	RESPONSE REGULATOR receiver
L6483_RS12585	COG2205	protein histidine kinase activity
L6483_RS12595	COG0488	(ABC) transporter
L6483_RS12605	COG1136	(ABC) transporter
L6483_RS12610	COG0577	efflux transmembrane transporter activity
L6483_RS12635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS12645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L6483_RS12750	COG2124	cytochrome p450
L6483_RS12785	COG0561	phosphatase activity
L6483_RS12790	COG5002	protein histidine kinase activity
L6483_RS12800	COG1819	glycosyl
L6483_RS12805	COG1794	racemase activity, acting on amino acids and derivatives
L6483_RS12840	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6483_RS12845	COG0604	alcohol dehydrogenase
L6483_RS12850	COG0671	phosphoesterase, PA-phosphatase related
L6483_RS12855	COG0768	penicillin binding
L6483_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS12875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6483_RS12915	COG0693	protein deglycase activity
L6483_RS12940	COG2814	Major facilitator Superfamily
L6483_RS12955	COG0584	glycerophosphoryl diester phosphodiesterase
L6483_RS12975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS12980	COG0697	spore germination
L6483_RS13000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6483_RS13010	COG2223	nitrite transmembrane transporter activity
L6483_RS13025	COG2816	NAD+ diphosphatase activity
L6483_RS13030	COG0592	DNA-directed DNA polymerase activity
L6483_RS13035	COG1051	belongs to the nudix hydrolase family
L6483_RS13065	COG3878	Protein conserved in bacteria
L6483_RS13090	COG4667	esterase of the alpha-beta hydrolase superfamily
L6483_RS13115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L6483_RS13130	COG0322	excinuclease ABC activity
L6483_RS13170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6483_RS13195	COG1011	Hydrolase
L6483_RS13215	COG1523	belongs to the glycosyl hydrolase 13 family
L6483_RS13220	COG3227	Zinc metalloprotease (Elastase)
L6483_RS13240	COG0201	protein transport
L6483_RS13250	COG0697	spore germination
L6483_RS13255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS13290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS13305	COG2959	enzyme of heme biosynthesis
L6483_RS13335	COG3844	kynureninase activity
L6483_RS13340	COG1309	transcriptional regulator
L6483_RS13370	COG3284	Transcriptional regulator
L6483_RS13390	COG1349	DNA-binding transcription factor activity
L6483_RS13400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L6483_RS13405	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6483_RS13410	COG0022	dehydrogenase e1 component
L6483_RS13415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6483_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS13440	COG1051	belongs to the nudix hydrolase family
L6483_RS13460	COG4176	ABC-type proline glycine betaine transport system permease component
L6483_RS13465	COG0517	IMP dehydrogenase activity
L6483_RS13465	COG4175	Glycine betaine
L6483_RS13490	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
L6483_RS13495	COG2153	protein acetylation
L6483_RS13500	COG3397	chitin binding
L6483_RS13515	COG2205	protein histidine kinase activity
L6483_RS13520	COG2226	methyltransferase
L6483_RS13525	COG2315	Protein conserved in bacteria
L6483_RS13530	COG2153	protein acetylation
L6483_RS13585	COG3973	AAA domain
L6483_RS13605	COG0514	ATP-dependent DNA helicase (RecQ)
L6483_RS13625	COG4637	Psort location Cytoplasmic, score
L6483_RS13650	COG3397	chitin binding
L6483_RS13665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L6483_RS13670	COG1115	amino acid carrier protein
L6483_RS13675	COG1012	belongs to the aldehyde dehydrogenase family
L6483_RS13680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L6483_RS13690	COG3938	Belongs to the proline racemase family
L6483_RS13695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L6483_RS13735	COG0586	Pfam SNARE associated Golgi protein
L6483_RS13750	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L6483_RS13755	COG0519	Catalyzes the synthesis of GMP from XMP
L6483_RS13760	COG4166	transmembrane transport
L6483_RS13770	COG4948	Mandelate Racemase Muconate Lactonizing
L6483_RS13810	COG2936	dipeptidyl-peptidase activity
L6483_RS13815	COG5002	protein histidine kinase activity
L6483_RS13820	COG0745	RESPONSE REGULATOR receiver
L6483_RS13855	COG1164	Oligoendopeptidase f
L6483_RS13860	COG0531	amino acid
L6483_RS13865	COG1522	sequence-specific DNA binding
L6483_RS13870	COG1307	EDD domain protein, DegV family
L6483_RS13910	COG2814	Major facilitator Superfamily
L6483_RS13920	COG1664	Polymer-forming cytoskeletal
L6483_RS13925	COG0789	Transcriptional regulator
L6483_RS13930	COG4533	DNA binding
L6483_RS13935	COG2814	Major facilitator Superfamily
L6483_RS13935	COG0477	Major facilitator Superfamily
L6483_RS13955	COG2261	transglycosylase associated protein
L6483_RS14005	COG0436	Aminotransferase
L6483_RS14010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L6483_RS14015	COG5146	pantothenate kinase activity
L6483_RS14020	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
L6483_RS14035	COG1131	(ABC) transporter
L6483_RS14085	COG0628	permease
L6483_RS14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6483_RS14105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6483_RS14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6483_RS14125	COG2816	NAD+ diphosphatase activity
L6483_RS14145	COG2746	aminoglycoside 3-N-acetyltransferase activity
L6483_RS14170	COG0697	spore germination
L6483_RS14175	COG2318	DinB family
L6483_RS14180	COG0454	-acetyltransferase
L6483_RS14195	COG4912	Dna alkylation repair
L6483_RS14215	COG0861	Integral membrane protein TerC family
L6483_RS14220	COG1368	sulfuric ester hydrolase activity
L6483_RS14225	COG0488	(ABC) transporter
L6483_RS14235	COG1033	growth of symbiont in host cell
L6483_RS14235	COG2409	Drug exporters of the RND superfamily
L6483_RS14240	COG1309	transcriptional regulator
L6483_RS14260	COG0287	Prephenate dehydrogenase
L6483_RS14265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
L6483_RS14275	COG1605	Chorismate mutase
L6483_RS14275	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L6483_RS14310	COG3584	3D domain protein
L6483_RS14310	COG1388	LysM domain
L6483_RS14320	COG1595	DNA-templated transcription, initiation
L6483_RS14345	COG1879	ABC-type sugar transport system periplasmic component
L6483_RS14355	COG1172	Belongs to the binding-protein-dependent transport system permease family
L6483_RS14400	COG2390	Transcriptional regulator
L6483_RS14405	COG1070	Carbohydrate kinase
L6483_RS14435	COG2329	Antibiotic biosynthesis monooxygenase
L6483_RS14455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS14470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6483_RS14475	COG4187	Peptidase family M20/M25/M40
L6483_RS14480	COG1414	Transcriptional regulator
L6483_RS14485	COG0833	amino acid
L6483_RS14490	COG1690	Belongs to the RtcB family
L6483_RS14495	COG3239	Fatty acid desaturase
L6483_RS14500	COG1785	Belongs to the alkaline phosphatase family
L6483_RS14510	COG3655	Transcriptional regulator
L6483_RS14525	COG4377	Putative membrane peptidase family (DUF2324)
L6483_RS14535	COG3279	Response regulator of the LytR AlgR family
L6483_RS14545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS14550	COG0346	lactoylglutathione lyase activity
L6483_RS14575	COG0714	Associated with various cellular activities
L6483_RS14600	COG0463	Glycosyl transferase, family 2
L6483_RS14620	COG0463	Glycosyl transferase, family 2
L6483_RS14635	COG0753	catalase activity
L6483_RS14645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L6483_RS14655	COG1280	lysine exporter protein (LysE YggA)
L6483_RS14680	COG0714	Associated with various cellular activities
L6483_RS14800	COG0778	Nitroreductase
L6483_RS14805	COG1846	Transcriptional regulator
L6483_RS14840	COG1725	Transcriptional regulator
L6483_RS14860	COG0577	efflux transmembrane transporter activity
L6483_RS14860	COG1136	(ABC) transporter
L6483_RS14885	COG2207	Transcriptional regulator
L6483_RS14890	COG0456	acetyltransferase
L6483_RS14905	COG0697	spore germination
L6483_RS14910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS14955	COG0730	response to heat
L6483_RS14965	COG0833	amino acid
L6483_RS14975	COG4335	DNA alkylation repair
L6483_RS15010	COG0768	penicillin binding
L6483_RS15045	COG1984	allophanate hydrolase subunit 2
L6483_RS15050	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L6483_RS15055	COG1414	Transcriptional regulator
L6483_RS15075	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6483_RS15080	COG0640	Transcriptional regulator
L6483_RS15090	COG1960	acyl-CoA dehydrogenase activity
L6483_RS15105	COG3314	Sporulation integral membrane protein YlbJ
L6483_RS15130	COG0574	Belongs to the PEP-utilizing enzyme family
L6483_RS15130	COG3848	Pyruvate phosphate dikinase
L6483_RS15135	COG1819	glycosyl
L6483_RS15140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS15155	COG5577	PFAM Coat F domain
L6483_RS15160	COG3403	YqcI/YcgG family
L6483_RS15165	COG1280	lysine exporter protein (LysE YggA)
L6483_RS15170	COG1113	amino acid transport
L6483_RS15200	COG1063	alcohol dehydrogenase
L6483_RS15235	COG4974	Belongs to the 'phage' integrase family
L6483_RS15315	COG0753	catalase activity
L6483_RS15320	COG0598	Magnesium transport protein CorA
L6483_RS15360	COG0415	Belongs to the DNA photolyase family
L6483_RS15365	COG0288	reversible hydration of carbon dioxide
L6483_RS15375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L6483_RS15380	COG5609	conserved protein (DUF2294)
L6483_RS15395	COG0714	Associated with various cellular activities
L6483_RS15405	COG1575	Belongs to the MenA family. Type 1 subfamily
L6483_RS15415	COG0803	Belongs to the bacterial solute-binding protein 9 family
L6483_RS15420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L6483_RS15425	COG1121	(ABC) transporter
L6483_RS15440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS15450	COG0798	PFAM Bile acid sodium symporter
L6483_RS15455	COG0346	lactoylglutathione lyase activity
L6483_RS15460	COG0640	Transcriptional regulator
L6483_RS15470	COG0456	acetyltransferase
L6483_RS15480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6483_RS15480	COG3320	Male sterility
L6483_RS15485	COG1309	transcriptional regulator
L6483_RS15490	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS15495	COG1522	sequence-specific DNA binding
L6483_RS15510	COG0346	lactoylglutathione lyase activity
L6483_RS15550	COG2814	Major facilitator Superfamily
L6483_RS15575	COG0745	RESPONSE REGULATOR receiver
L6483_RS15580	COG5002	protein histidine kinase activity
L6483_RS15580	COG3850	Histidine kinase
L6483_RS15605	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L6483_RS15625	COG1476	TRANSCRIPTIONal
L6483_RS15650	COG0789	Transcriptional regulator
L6483_RS15655	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L6483_RS15670	COG1136	(ABC) transporter
L6483_RS15675	COG0577	efflux transmembrane transporter activity
L6483_RS15690	COG5002	protein histidine kinase activity
L6483_RS15690	COG3850	Histidine kinase
L6483_RS15700	COG2364	Membrane
L6483_RS15705	COG1846	Transcriptional regulator
L6483_RS15710	COG0456	acetyltransferase
L6483_RS15715	COG2808	Putative FMN-binding domain
L6483_RS15720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS15725	COG2271	Major facilitator Superfamily
L6483_RS15730	COG1556	Lactate utilization protein
L6483_RS15735	COG1139	Iron-sulfur cluster binding protein
L6483_RS15745	COG0583	DNA-binding transcription factor activity
L6483_RS15765	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6483_RS15780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L6483_RS15800	COG1595	DNA-templated transcription, initiation
L6483_RS15815	COG0662	Cupin 2, conserved barrel domain protein
L6483_RS15820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6483_RS15820	COG2207	Transcriptional regulator
L6483_RS15835	COG3409	Peptidoglycan-binding domain 1 protein
L6483_RS15835	COG5632	N-Acetylmuramoyl-L-alanine amidase
L6483_RS16135	COG4282	regulation of fungal-type cell wall biogenesis
L6483_RS16250	COG2373	Large extracellular alpha-helical protein
L6483_RS16270	COG0477	Major facilitator Superfamily
L6483_RS16280	COG1846	Transcriptional regulator
L6483_RS16285	COG2814	Major facilitator Superfamily
L6483_RS16295	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6483_RS16300	COG1131	(ABC) transporter
L6483_RS16320	COG2076	Multidrug Resistance protein
L6483_RS16325	COG1309	transcriptional regulator
L6483_RS16335	COG1476	TRANSCRIPTIONal
L6483_RS16350	COG2031	fatty acid transporter
L6483_RS16360	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6483_RS16395	COG1122	ATPase activity
L6483_RS16405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L6483_RS16420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L6483_RS16425	COG1288	antiporter activity
L6483_RS16435	COG3409	Peptidoglycan-binding domain 1 protein
L6483_RS16435	COG5632	N-Acetylmuramoyl-L-alanine amidase
L6483_RS16445	COG3620	sequence-specific DNA binding
L6483_RS16455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L6483_RS16475	COG1733	regulation of RNA biosynthetic process
L6483_RS16480	COG0778	Nitroreductase
L6483_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS16510	COG1131	(ABC) transporter
L6483_RS16535	COG1011	Hydrolase
L6483_RS16545	COG2365	Tyrosine phosphatase family
L6483_RS16570	COG0346	lactoylglutathione lyase activity
L6483_RS16575	COG1940	carbohydrate kinase activity
L6483_RS16585	COG0110	maltose O-acetyltransferase activity
L6483_RS16595	COG1136	(ABC) transporter
L6483_RS16595	COG0577	efflux transmembrane transporter activity
L6483_RS16615	COG0628	permease
L6483_RS16635	COG2226	methyltransferase
L6483_RS16645	COG0477	Major facilitator Superfamily
L6483_RS16675	COG1253	flavin adenine dinucleotide binding
L6483_RS16680	COG0789	Transcriptional regulator
L6483_RS16690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L6483_RS16720	COG0697	spore germination
L6483_RS16725	COG1357	PFAM Pentapeptide repeats (8 copies)
L6483_RS16730	COG3813	Protein conserved in bacteria
L6483_RS16740	COG2706	6-phosphogluconolactonase activity
L6483_RS16755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L6483_RS16760	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L6483_RS16770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L6483_RS16785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L6483_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS16845	COG0814	amino acid
L6483_RS16875	COG1393	Belongs to the ArsC family
L6483_RS16880	COG1733	regulation of RNA biosynthetic process
L6483_RS16885	COG2188	Transcriptional regulator
L6483_RS16890	COG0673	inositol 2-dehydrogenase activity
L6483_RS16900	COG1733	regulation of RNA biosynthetic process
L6483_RS16905	COG1733	regulation of RNA biosynthetic process
L6483_RS16925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS16970	COG0318	PFAM AMP-dependent synthetase and ligase
L6483_RS16975	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6483_RS16980	COG1733	regulation of RNA biosynthetic process
L6483_RS17010	COG1191	sigma factor activity
L6483_RS17030	COG1309	transcriptional regulator
L6483_RS17050	COG3152	Membrane
L6483_RS17075	COG1151	hydroxylamine reductase activity
L6483_RS17085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS17090	COG3757	hydrolase, family 25
L6483_RS17090	COG3409	Peptidoglycan-binding domain 1 protein
L6483_RS17125	COG2072	flavoprotein involved in K transport
L6483_RS17160	COG1113	amino acid transport
L6483_RS17165	COG2814	Major facilitator Superfamily
L6483_RS17195	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L6483_RS17200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6483_RS17220	COG3739	integral membrane protein
L6483_RS17225	COG0384	phenazine biosynthesis protein PhzF
L6483_RS17255	COG0583	DNA-binding transcription factor activity
L6483_RS17275	COG1193	negative regulation of DNA recombination
L6483_RS17290	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L6483_RS17295	COG1164	Oligoendopeptidase f
L6483_RS17305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L6483_RS17330	COG0584	glycerophosphoryl diester phosphodiesterase
L6483_RS17360	COG0604	alcohol dehydrogenase
L6483_RS17370	COG0457	Tetratricopeptide repeat
L6483_RS17380	COG2808	Putative FMN-binding domain
L6483_RS17390	COG0456	acetyltransferase
L6483_RS17390	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6483_RS17400	COG0385	Bile acid
L6483_RS17405	COG0277	FAD linked oxidase domain protein
L6483_RS17435	COG1216	Glycosyl transferase, family 2
L6483_RS17440	COG1024	Enoyl-CoA hydratase
L6483_RS17450	COG1285	pathogenesis
L6483_RS17465	COG2514	catechol 2,3-dioxygenase activity
L6483_RS17470	COG2720	vancomycin resistance protein
L6483_RS17510	COG0716	FMN binding
L6483_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS17550	COG0165	Argininosuccinate lyase
L6483_RS17565	COG4145	pantothenate transmembrane transporter activity
L6483_RS17615	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS17625	COG1657	PFAM Prenyltransferase squalene oxidase
L6483_RS17630	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L6483_RS17635	COG2962	Rard protein
L6483_RS17640	COG3326	Membrane
L6483_RS17655	COG0489	protein tyrosine kinase activity
L6483_RS17665	COG0314	molybdopterin synthase activity
L6483_RS17670	COG0303	'Molybdopterin
L6483_RS17675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6483_RS17680	COG2116	formate transmembrane transporter activity
L6483_RS17690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L6483_RS17695	COG5609	conserved protein (DUF2294)
L6483_RS17700	COG2427	Protein of unknown function (DUF1641)
L6483_RS17705	COG3383	formate dehydrogenase (NAD+) activity
L6483_RS17710	COG0697	spore germination
L6483_RS17750	COG2226	methyltransferase
L6483_RS17755	COG4166	transmembrane transport
L6483_RS17765	COG4166	transmembrane transport
L6483_RS17770	COG4166	transmembrane transport
L6483_RS17775	COG1301	dicarboxylic acid transport
L6483_RS17780	COG1316	TRANSCRIPTIONal
L6483_RS17790	COG1595	DNA-templated transcription, initiation
L6483_RS17805	COG1131	(ABC) transporter
L6483_RS17830	COG0673	inositol 2-dehydrogenase activity
L6483_RS17835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L6483_RS17840	COG0187	DNA topoisomerase II activity
L6483_RS17845	COG1832	CoA-binding protein
L6483_RS17850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6483_RS17855	COG0745	RESPONSE REGULATOR receiver
L6483_RS17875	COG4841	protein insertion into membrane
L6483_RS17880	COG0824	Thioesterase
L6483_RS17910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6483_RS17920	COG1132	(ABC) transporter
L6483_RS17925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L6483_RS17965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L6483_RS17980	COG0183	Belongs to the thiolase family
L6483_RS17985	COG0318	PFAM AMP-dependent synthetase and ligase
L6483_RS17990	COG1268	BioY protein
L6483_RS17995	COG0318	PFAM AMP-dependent synthetase and ligase
L6483_RS18055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS18070	COG0400	carboxylic ester hydrolase activity
L6483_RS18075	COG0346	lactoylglutathione lyase activity
L6483_RS18080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L6483_RS18085	COG0069	glutamate synthase activity
L6483_RS18090	COG1902	pentaerythritol trinitrate reductase activity
L6483_RS18095	COG1329	Transcriptional regulator
L6483_RS18100	COG0010	Belongs to the arginase family
L6483_RS18125	COG2226	methyltransferase
L6483_RS18160	COG3344	reverse transcriptase
L6483_RS18170	COG4846	Membrane protein involved in cytochrome C biogenesis
L6483_RS18175	COG0785	Cytochrome C biogenesis protein
L6483_RS18185	COG1473	amidohydrolase
L6483_RS18195	COG1131	(ABC) transporter
L6483_RS18205	COG0583	DNA-binding transcription factor activity
L6483_RS18215	COG1346	cytolysis
L6483_RS18230	COG0730	response to heat
L6483_RS18255	COG1132	(ABC) transporter
L6483_RS18260	COG1132	(ABC) transporter
L6483_RS18290	COG3639	organic phosphonate transmembrane transporter activity
L6483_RS18295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
L6483_RS18300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6483_RS18305	COG0737	Belongs to the 5'-nucleotidase family
L6483_RS18315	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6483_RS18335	COG1695	Transcriptional regulator
L6483_RS18340	COG0174	glutamine synthetase
L6483_RS18345	COG0789	Transcriptional regulator
L6483_RS18350	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L6483_RS18355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L6483_RS18360	COG2860	membrane
L6483_RS18365	COG0464	growth
L6483_RS18400	COG1388	LysM domain
L6483_RS18400	COG3584	3D domain protein
L6483_RS18405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6483_RS18405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L6483_RS18405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L6483_RS18410	COG1105	Belongs to the carbohydrate kinase PfkB family
L6483_RS18415	COG1349	DNA-binding transcription factor activity
L6483_RS18420	COG1979	alcohol dehydrogenase
L6483_RS18425	COG2322	membrane
L6483_RS18435	COG1113	amino acid transport
L6483_RS18445	COG1408	metallophosphoesterase
L6483_RS18450	COG2116	formate transmembrane transporter activity
L6483_RS18460	COG2217	Heavy metal translocating P-type atpase
L6483_RS18465	COG2608	mercury ion transmembrane transporter activity
L6483_RS18470	COG1937	Protein conserved in bacteria
L6483_RS18510	COG2819	hydrolase of the alpha beta superfamily
L6483_RS18515	COG1120	ATPase activity
L6483_RS18520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS18525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS18530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6483_RS18535	COG0708	Exodeoxyribonuclease III
L6483_RS18540	COG2169	Transcriptional regulator
L6483_RS18545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L6483_RS18550	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L6483_RS18560	COG2364	Membrane
L6483_RS18575	COG2267	carboxylic ester hydrolase activity
L6483_RS18580	COG0346	lactoylglutathione lyase activity
L6483_RS18585	COG5001	Diguanylate cyclase
L6483_RS18585	COG3300	MHYT domain
L6483_RS18605	COG1380	Effector of murein hydrolase LrgA
L6483_RS18610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L6483_RS18630	COG1404	Belongs to the peptidase S8 family
L6483_RS18635	COG3773	Cell wall hydrolase
L6483_RS18640	COG0562	UDP-galactopyranose mutase
L6483_RS18645	COG1368	sulfuric ester hydrolase activity
L6483_RS18650	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L6483_RS18670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L6483_RS18675	COG2814	Major facilitator Superfamily
L6483_RS18685	COG0640	Transcriptional regulator
L6483_RS18705	COG4550	Control of competence regulator ComK, YlbF/YmcA
L6483_RS18715	COG1013	pyruvate-flavodoxin oxidoreductase activity
L6483_RS18720	COG0674	pyruvate-flavodoxin oxidoreductase activity
L6483_RS18720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L6483_RS18730	COG2359	stage V sporulation protein S
L6483_RS18735	COG1692	metallophosphoesterase
L6483_RS18770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L6483_RS18775	COG1426	Protein conserved in bacteria
L6483_RS18790	COG0300	oxidoreductase activity
L6483_RS18795	COG0612	Peptidase, M16
L6483_RS18800	COG0612	Peptidase, M16
L6483_RS18805	COG1079	Belongs to the binding-protein-dependent transport system permease family
L6483_RS18810	COG4603	Belongs to the binding-protein-dependent transport system permease family
L6483_RS18815	COG3845	ABC transporter
L6483_RS18820	COG1744	ABC transporter substrate-binding protein PnrA-like
L6483_RS18825	COG2188	Transcriptional regulator
L6483_RS18830	COG1674	ftsk spoiiie
L6483_RS18840	COG0740	serine-type endopeptidase activity
L6483_RS18845	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6483_RS18855	COG0527	aspartate kinase activity
L6483_RS18860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L6483_RS18865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L6483_RS18870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L6483_RS18875	COG1873	PFAM PRC-barrel domain
L6483_RS18880	COG0612	Peptidase, M16
L6483_RS18885	COG0726	polysaccharide deacetylase
L6483_RS18900	COG0196	riboflavin kinase activity
L6483_RS18915	COG1550	Protein conserved in bacteria
L6483_RS18925	COG1358	cellular component organization or biogenesis
L6483_RS18930	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L6483_RS18935	COG0195	Participates in both transcription termination and antitermination
L6483_RS18965	COG0750	zinc metalloprotease
L6483_RS18975	COG4589	Belongs to the CDS family
L6483_RS18990	COG0528	UMP kinase activity
L6483_RS19020	COG4974	Belongs to the 'phage' integrase family
L6483_RS19030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L6483_RS19035	COG0758	DNA mediated transformation
L6483_RS19040	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L6483_RS19080	COG1837	Belongs to the UPF0109 family
L6483_RS19090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L6483_RS19100	COG0552	protein localization to endoplasmic reticulum
L6483_RS19105	COG1196	nuclear chromosome segregation
L6483_RS19115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L6483_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS19125	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L6483_RS19140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L6483_RS19145	COG1461	Dihydroxyacetone kinase
L6483_RS19150	COG1302	Protein conserved in bacteria
L6483_RS19165	COG1564	THIamine pyrophosphokinase
L6483_RS19170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L6483_RS19175	COG1162	GTPase activity
L6483_RS19180	COG2815	serine threonine protein kinase
L6483_RS19180	COG0515	serine threonine protein kinase
L6483_RS19185	COG0631	protein serine/threonine phosphatase activity
L6483_RS19195	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L6483_RS19195	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L6483_RS19205	COG0242	peptide deformylase activity
L6483_RS19210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L6483_RS19215	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L6483_RS19235	COG1561	YicC-like family, N-terminal region
L6483_RS19240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L6483_RS19250	COG0006	proline dipeptidase activity
L6483_RS19270	COG3069	C4-dicarboxylate transmembrane transporter activity
L6483_RS19330	COG0564	pseudouridine synthase activity
L6483_RS19350	COG3599	regulation of cell shape
L6483_RS19355	COG2302	S4 RNA-binding domain
L6483_RS19360	COG0762	integral membrane protein
L6483_RS19370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L6483_RS19375	COG1496	oxidoreductase activity
L6483_RS19380	COG1873	PFAM PRC-barrel domain
L6483_RS19385	COG1191	sigma factor activity
L6483_RS19390	COG1191	sigma factor activity
L6483_RS19400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L6483_RS19405	COG0849	cell division
L6483_RS19410	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L6483_RS19425	COG0772	Belongs to the SEDS family
L6483_RS19440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L6483_RS19445	COG0768	penicillin binding
L6483_RS19450	COG0768	penicillin binding
L6483_RS19455	COG4839	cell division protein FtsL
L6483_RS19470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L6483_RS19485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L6483_RS19490	COG1399	metal-binding, possibly nucleic acid-binding protein
L6483_RS19500	COG3480	Lon protease (S16) C-terminal proteolytic domain
L6483_RS19505	COG1752	Esterase of the alpha-beta hydrolase superfamily
L6483_RS19510	COG3314	Sporulation integral membrane protein YlbJ
L6483_RS19520	COG0742	ribosomal rna small subunit methyltransferase
L6483_RS19535	COG3679	Belongs to the UPF0342 family
L6483_RS19540	COG0406	alpha-ribazole phosphatase activity
L6483_RS19555	COG2340	Cysteine-rich secretory protein family
L6483_RS19570	COG3336	cytochrome c oxidase
L6483_RS19605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L6483_RS19610	COG0772	Belongs to the SEDS family
L6483_RS19620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L6483_RS19625	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L6483_RS19635	COG4896	Protein conserved in bacteria
L6483_RS19650	COG1217	gtp-binding protein TYPA
L6483_RS19660	COG0483	inositol monophosphate 1-phosphatase activity
L6483_RS19680	COG1982	Orn Lys Arg decarboxylase major
L6483_RS19730	COG0022	dehydrogenase e1 component
L6483_RS19735	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6483_RS19745	COG0242	peptide deformylase activity
L6483_RS19750	COG0561	phosphatase activity
L6483_RS19760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L6483_RS19765	COG0569	domain protein
L6483_RS19785	COG0583	DNA-binding transcription factor activity
L6483_RS19790	COG0517	IMP dehydrogenase activity
L6483_RS19800	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
L6483_RS19810	COG4703	Protein of unknown function (DUF1797)
L6483_RS19825	COG2200	EAL domain
L6483_RS19830	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS19835	COG1408	metallophosphoesterase
L6483_RS19845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
L6483_RS19880	COG2814	Major facilitator Superfamily
L6483_RS19900	COG3209	COG3209 Rhs family protein
L6483_RS19910	COG2205	protein histidine kinase activity
L6483_RS19920	COG0436	Aminotransferase
L6483_RS19925	COG1609	Transcriptional regulator
L6483_RS19930	COG3833	ABC-type maltose transport systems, permease component
L6483_RS19935	COG1175	transmembrane transport
L6483_RS19940	COG2182	Extracellular solute-binding protein
L6483_RS19950	COG0366	Alpha amylase catalytic
L6483_RS19955	COG3842	ATPase activity
L6483_RS19995	COG0183	Belongs to the thiolase family
L6483_RS20035	COG1695	Transcriptional regulator
L6483_RS20040	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS20060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L6483_RS20065	COG0436	Aminotransferase
L6483_RS20100	COG2084	Dehydrogenase
L6483_RS20105	COG2199	diguanylate cyclase activity
L6483_RS20110	COG0778	Nitroreductase
L6483_RS20135	COG1263	PTS System
L6483_RS20135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS20135	COG2190	(PTS) system
L6483_RS20140	COG3711	transcriptional antiterminator
L6483_RS20150	COG2188	Transcriptional regulator
L6483_RS20160	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L6483_RS20185	COG1547	Domain of unknown function (DUF309)
L6483_RS20190	COG0456	acetyltransferase
L6483_RS20200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L6483_RS20205	COG4086	secreted protein
L6483_RS20210	COG0561	phosphatase activity
L6483_RS20215	COG0697	spore germination
L6483_RS20230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6483_RS20255	COG0733	neurotransmitter:sodium symporter activity
L6483_RS20275	COG1686	Belongs to the peptidase S11 family
L6483_RS20280	COG1725	Transcriptional regulator
L6483_RS20285	COG1131	(ABC) transporter
L6483_RS20305	COG1846	Transcriptional regulator
L6483_RS20320	COG0598	Magnesium transport protein CorA
L6483_RS20345	COG4974	Belongs to the 'phage' integrase family
L6483_RS20355	COG0735	belongs to the Fur family
L6483_RS20360	COG1300	Membrane
L6483_RS20380	COG0667	Aldo Keto reductase
L6483_RS20385	COG0656	L-ascorbic acid biosynthetic process
L6483_RS20390	COG0456	acetyltransferase
L6483_RS20390	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L6483_RS20400	COG4085	toxin activity
L6483_RS20400	COG0737	Belongs to the 5'-nucleotidase family
L6483_RS20400	COG1525	nuclease
L6483_RS20410	COG0596	Alpha beta hydrolase
L6483_RS20415	COG2056	Na+-H+ antiporter family
L6483_RS20420	COG1609	Transcriptional regulator
L6483_RS20425	COG0454	-acetyltransferase
L6483_RS20430	COG1073	alpha beta
L6483_RS20445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L6483_RS20445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L6483_RS20450	COG0307	riboflavin synthase, alpha
L6483_RS20475	COG4106	trans-aconitate 2-methyltransferase activity
L6483_RS20480	COG1073	alpha beta
L6483_RS20480	COG2226	methyltransferase
L6483_RS20495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L6483_RS20505	COG1757	Na H antiporter
L6483_RS20510	COG0737	Belongs to the 5'-nucleotidase family
L6483_RS20520	COG1522	sequence-specific DNA binding
L6483_RS20540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L6483_RS20565	COG0300	oxidoreductase activity
L6483_RS20570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS20575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6483_RS20580	COG1760	l-serine dehydratase
L6483_RS20585	COG1760	l-serine dehydratase
L6483_RS20605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L6483_RS20615	COG2195	Cleaves the N-terminal amino acid of tripeptides
L6483_RS20620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS20635	COG1376	ErfK ybiS ycfS ynhG family protein
L6483_RS20640	COG4129	membrane
L6483_RS20645	COG1126	abc transporter atp-binding protein
L6483_RS20650	COG0765	amino acid transport
L6483_RS20655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L6483_RS20665	COG2816	NAD+ diphosphatase activity
L6483_RS20670	COG0772	Belongs to the SEDS family
L6483_RS20675	COG0508	dehydrogenase complex catalyzes the overall conversion of
L6483_RS20680	COG0022	dehydrogenase e1 component
L6483_RS20685	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L6483_RS20690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L6483_RS20705	COG0280	phosphate acetyltransferase
L6483_RS20710	COG3829	transcription factor binding
L6483_RS20710	COG3290	protein histidine kinase activity
L6483_RS20720	COG0584	glycerophosphoryl diester phosphodiesterase
L6483_RS20725	COG3093	addiction module antidote protein HigA
L6483_RS20735	COG0745	RESPONSE REGULATOR receiver
L6483_RS20740	COG0750	zinc metalloprotease
L6483_RS20745	COG0497	DNA recombination
L6483_RS20755	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L6483_RS20765	COG0142	geranyltranstransferase activity
L6483_RS20790	COG1302	Protein conserved in bacteria
L6483_RS20795	COG0439	Biotin carboxylase
L6483_RS20800	COG0511	ligase activity, forming carbon-carbon bonds
L6483_RS20845	COG3854	ATPases associated with a variety of cellular activities
L6483_RS20870	COG0006	proline dipeptidase activity
L6483_RS20885	COG3872	metal-dependent enzyme
L6483_RS20895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L6483_RS20930	COG0095	Lipoate-protein ligase
L6483_RS20935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6483_RS20940	COG1609	Transcriptional regulator
L6483_RS20950	COG2076	Multidrug Resistance protein
L6483_RS20955	COG2076	Multidrug Resistance protein
L6483_RS20990	COG1131	(ABC) transporter
L6483_RS20995	COG1725	Transcriptional regulator
L6483_RS21025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6483_RS21080	COG4970	Tfp pilus assembly protein FimT
L6483_RS21090	COG1459	type II secretion system
L6483_RS21095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L6483_RS21145	COG1410	methionine synthase
L6483_RS21145	COG0646	methionine synthase
L6483_RS21150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L6483_RS21150	COG0646	methionine synthase
L6483_RS21155	COG0626	cystathionine gamma-synthase activity
L6483_RS21160	COG0626	cystathionine gamma-synthase activity
L6483_RS21180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS21190	COG1940	carbohydrate kinase activity
L6483_RS21195	COG4483	Protein conserved in bacteria
L6483_RS21200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L6483_RS21205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L6483_RS21210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L6483_RS21215	COG0704	Plays a role in the regulation of phosphate uptake
L6483_RS21225	COG0581	inorganic phosphate transmembrane transporter activity
L6483_RS21230	COG0573	inorganic phosphate transmembrane transporter activity
L6483_RS21235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L6483_RS21245	COG0768	penicillin binding
L6483_RS21250	COG0477	Major facilitator Superfamily
L6483_RS21255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6483_RS21280	COG0735	belongs to the Fur family
L6483_RS21285	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L6483_RS21290	COG1121	(ABC) transporter
L6483_RS21295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS21325	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L6483_RS21330	COG2384	SAM-dependent methyltransferase
L6483_RS21335	COG2010	Cytochrome c
L6483_RS21340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L6483_RS21345	COG0358	DNA primase activity
L6483_RS21355	COG0517	IMP dehydrogenase activity
L6483_RS21370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L6483_RS21375	COG0295	cytidine deaminase activity
L6483_RS21380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L6483_RS21390	COG1480	7TM receptor with intracellular HD hydrolase
L6483_RS21395	COG1702	phosphate starvation-inducible protein PhoH
L6483_RS21410	COG1610	YqeY-like protein
L6483_RS21415	COG0828	Belongs to the bacterial ribosomal protein bS21 family
L6483_RS21420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L6483_RS21425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L6483_RS21455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L6483_RS21460	COG1733	regulation of RNA biosynthetic process
L6483_RS21485	COG1466	dna polymerase III delta subunit
L6483_RS21495	COG0658	competence protein
L6483_RS21495	COG2333	competence protein COMEC
L6483_RS21500	COG2131	deaminase
L6483_RS21505	COG1555	photosystem II stabilization
L6483_RS21505	COG1596	polysaccharide export
L6483_RS21510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L6483_RS21515	COG2226	methyltransferase
L6483_RS21520	COG0799	negative regulation of ribosome biogenesis
L6483_RS21525	COG1713	HD superfamily hydrolase involved in NAD metabolism
L6483_RS21535	COG1534	Rna-binding protein
L6483_RS21545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L6483_RS21550	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L6483_RS21575	COG1595	DNA-templated transcription, initiation
L6483_RS21585	COG0778	Nitroreductase
L6483_RS21590	COG2357	RelA SpoT domain protein
L6483_RS21600	COG1785	Belongs to the alkaline phosphatase family
L6483_RS21610	COG2267	carboxylic ester hydrolase activity
L6483_RS21645	COG1404	Belongs to the peptidase S8 family
L6483_RS21650	COG3186	Phenylalanine-4-hydroxylase
L6483_RS21660	COG2514	catechol 2,3-dioxygenase activity
L6483_RS21665	COG2259	Doxx family
L6483_RS21705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L6483_RS21715	COG1454	alcohol dehydrogenase
L6483_RS21715	COG1012	belongs to the aldehyde dehydrogenase family
L6483_RS21720	COG0626	cystathionine gamma-synthase activity
L6483_RS21725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L6483_RS21750	COG0768	penicillin binding
L6483_RS21765	COG0826	peptidase U32
L6483_RS21770	COG0826	peptidase U32
L6483_RS21775	COG4122	O-methyltransferase activity
L6483_RS21780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L6483_RS21810	COG0628	permease
L6483_RS21830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L6483_RS21845	COG1104	cysteine desulfurase activity
L6483_RS21850	COG1959	2 iron, 2 sulfur cluster binding
L6483_RS21855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L6483_RS21865	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L6483_RS21905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L6483_RS21915	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L6483_RS21915	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L6483_RS21920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L6483_RS21925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L6483_RS21925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L6483_RS21935	COG2244	polysaccharide biosynthetic process
L6483_RS21940	COG2323	membrane
L6483_RS21950	COG1862	Preprotein translocase
L6483_RS21980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L6483_RS21990	COG0697	spore germination
L6483_RS21995	COG0640	Transcriptional regulator
L6483_RS22020	COG0157	Belongs to the NadC ModD family
L6483_RS22025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L6483_RS22030	COG1104	cysteine desulfurase activity
L6483_RS22035	COG1827	regulation of RNA biosynthetic process
L6483_RS22040	COG2258	MOSC domain
L6483_RS22045	COG0077	Prephenate dehydratase
L6483_RS22050	COG0577	efflux transmembrane transporter activity
L6483_RS22055	COG0577	efflux transmembrane transporter activity
L6483_RS22060	COG1136	(ABC) transporter
L6483_RS22065	COG5002	protein histidine kinase activity
L6483_RS22070	COG0745	RESPONSE REGULATOR receiver
L6483_RS22080	COG3290	protein histidine kinase activity
L6483_RS22090	COG2868	ribosomal protein
L6483_RS22095	COG0261	This protein binds to 23S rRNA in the presence of protein L20
L6483_RS22100	COG1530	ribonuclease E activity
L6483_RS22105	COG1994	Peptidase M50
L6483_RS22110	COG0739	heme binding
L6483_RS22115	COG2894	cell division
L6483_RS22135	COG1077	Cell shape determining protein MreB Mrl
L6483_RS22175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L6483_RS22175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L6483_RS22300	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
L6483_RS22340	COG0285	dihydrofolate synthase activity
L6483_RS22355	COG1388	LysM domain
L6483_RS22365	COG0113	porphobilinogen synthase activity
L6483_RS22370	COG1587	Uroporphyrinogen-III synthase
L6483_RS22380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L6483_RS22390	COG1846	Transcriptional regulator
L6483_RS22395	COG1764	response to oxidative stress
L6483_RS22410	COG0470	DNA polymerase III
L6483_RS22410	COG1067	ATP-dependent peptidase activity
L6483_RS22460	COG0622	Phosphoesterase
L6483_RS22475	COG5401	PFAM Sporulation and spore germination
L6483_RS22490	COG2197	response regulator
L6483_RS22495	COG2233	PERMEase
L6483_RS22500	COG0402	S-adenosylhomocysteine deaminase activity
L6483_RS22505	COG1983	PspC domain protein
L6483_RS22510	COG1396	sequence-specific DNA binding
L6483_RS22515	COG0697	spore germination
L6483_RS22525	COG1959	2 iron, 2 sulfur cluster binding
L6483_RS22530	COG1668	transmembrane transport
L6483_RS22535	COG4152	abc transporter atp-binding protein
L6483_RS22540	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
L6483_RS22545	COG1360	Flagellar Motor Protein
L6483_RS22550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L6483_RS22555	COG1876	peptidase activity
L6483_RS22560	COG0824	Thioesterase
L6483_RS22565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L6483_RS22570	COG1053	succinate dehydrogenase
L6483_RS22575	COG2009	succinate dehydrogenase
L6483_RS22580	COG1719	4-vinyl reductase, 4VR
L6483_RS22590	COG3118	belongs to the thioredoxin family
L6483_RS22595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L6483_RS22600	COG2086	electron transfer activity
L6483_RS22605	COG1024	Enoyl-CoA hydratase
L6483_RS22610	COG1309	transcriptional regulator
L6483_RS22615	COG0318	PFAM AMP-dependent synthetase and ligase
L6483_RS22635	COG2318	DinB family
L6483_RS22660	COG1131	(ABC) transporter
L6483_RS22665	COG2205	protein histidine kinase activity
L6483_RS22670	COG0745	RESPONSE REGULATOR receiver
L6483_RS22680	COG4895	conserved protein (DUF2196)
L6483_RS22685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L6483_RS22700	COG4509	Sortase family
L6483_RS22705	COG1120	ATPase activity
L6483_RS22720	COG5386	Cell surface protein
L6483_RS22725	COG5386	Cell surface protein
L6483_RS22730	COG1114	Component of the transport system for branched-chain amino acids
L6483_RS22735	COG1187	pseudouridine synthase activity
L6483_RS22745	COG1796	DNA polymerase
L6483_RS22745	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L6483_RS22750	COG1286	toxin biosynthetic process
L6483_RS22795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L6483_RS22805	COG1418	mRNA catabolic process
L6483_RS22815	COG2814	Major facilitator Superfamily
L6483_RS22820	COG1566	PFAM secretion protein HlyD family protein
L6483_RS22825	COG1309	transcriptional regulator
L6483_RS22830	COG1363	Peptidase, m42
L6483_RS22855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L6483_RS22865	COG1484	DNA-dependent DNA replication
L6483_RS22870	COG3611	Membrane attachment protein
L6483_RS22880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
L6483_RS22885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L6483_RS22890	COG0237	dephospho-CoA kinase activity
L6483_RS22895	COG1971	Probably functions as a manganese efflux pump
L6483_RS22905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6483_RS22905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L6483_RS22910	COG5002	protein histidine kinase activity
L6483_RS22915	COG0745	RESPONSE REGULATOR receiver
L6483_RS22935	COG0538	isocitrate dehydrogenase activity
L6483_RS22940	COG0372	Belongs to the citrate synthase family
L6483_RS22950	COG0628	permease
L6483_RS22955	COG3030	protein affecting phage T7 exclusion by the F plasmid
L6483_RS22980	COG1725	Transcriptional regulator
L6483_RS22985	COG0281	malic enzyme
L6483_RS22990	COG0587	DNA-directed DNA polymerase activity
L6483_RS23005	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L6483_RS23020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6483_RS23030	COG4109	DRTGG domain
L6483_RS23045	COG0006	proline dipeptidase activity
L6483_RS23080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS23085	COG0662	Cupin 2, conserved barrel domain protein
L6483_RS23100	COG1028	Short-chain dehydrogenase reductase Sdr
L6483_RS23105	COG0589	response to stress
L6483_RS23145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS23160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L6483_RS23165	COG0827	DNA restriction-modification system
L6483_RS23170	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L6483_RS23180	COG3874	Sporulation protein YtfJ
L6483_RS23195	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L6483_RS23205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6483_RS23220	COG1104	cysteine desulfurase activity
L6483_RS23230	COG0583	DNA-binding transcription factor activity
L6483_RS23235	COG0697	spore germination
L6483_RS23240	COG1309	transcriptional regulator
L6483_RS23245	COG1956	GAF domain-containing protein
L6483_RS23250	COG0626	cystathionine gamma-synthase activity
L6483_RS23295	COG1595	DNA-templated transcription, initiation
L6483_RS23305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L6483_RS23310	COG0454	-acetyltransferase
L6483_RS23315	COG0517	IMP dehydrogenase activity
L6483_RS23320	COG0123	including yeast histone deacetylase and acetoin utilization protein
L6483_RS23325	COG2267	carboxylic ester hydrolase activity
L6483_RS23335	COG0745	RESPONSE REGULATOR receiver
L6483_RS23345	COG0666	response to abiotic stimulus
L6483_RS23350	COG2972	Histidine kinase
L6483_RS23350	COG0745	RESPONSE REGULATOR receiver
L6483_RS23405	COG1609	Transcriptional regulator
L6483_RS23410	COG4851	CamS sex pheromone cAM373 precursor
L6483_RS23415	COG3118	belongs to the thioredoxin family
L6483_RS23425	COG2309	aminopeptidase activity
L6483_RS23435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS23440	COG0697	spore germination
L6483_RS23445	COG0789	Transcriptional regulator
L6483_RS23450	COG1695	Transcriptional regulator
L6483_RS23470	COG1674	ftsk spoiiie
L6483_RS23470	COG1674	ftsk spoiiie
L6483_RS23480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6483_RS23490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6483_RS23495	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
L6483_RS23500	COG1363	Peptidase, m42
L6483_RS23510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS23525	COG0510	thiamine kinase activity
L6483_RS23530	COG1523	belongs to the glycosyl hydrolase 13 family
L6483_RS23540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L6483_RS23545	COG1349	DNA-binding transcription factor activity
L6483_RS23550	COG1187	pseudouridine synthase activity
L6483_RS23555	COG2244	polysaccharide biosynthetic process
L6483_RS23560	COG2081	HI0933 family
L6483_RS23570	COG2814	Major facilitator Superfamily
L6483_RS23580	COG3832	glyoxalase III activity
L6483_RS23600	COG1329	Transcriptional regulator
L6483_RS23625	COG0314	molybdopterin synthase activity
L6483_RS23640	COG1763	Mo-molybdopterin cofactor biosynthetic process
L6483_RS23645	COG0303	'Molybdopterin
L6483_RS23655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L6483_RS23660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L6483_RS23690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L6483_RS23700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L6483_RS23745	COG2814	Major facilitator Superfamily
L6483_RS23755	COG0475	glutathione-regulated potassium exporter activity
L6483_RS23760	COG0490	domain, Protein
L6483_RS23765	COG0582	viral genome integration into host DNA
L6483_RS23775	COG1136	(ABC) transporter
L6483_RS23795	COG1242	4 iron, 4 sulfur cluster binding
L6483_RS23800	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L6483_RS23805	COG3328	transposase activity
L6483_RS23820	COG1794	racemase activity, acting on amino acids and derivatives
L6483_RS23845	COG2267	carboxylic ester hydrolase activity
L6483_RS23850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L6483_RS23855	COG0671	phosphoesterase, PA-phosphatase related
L6483_RS23860	COG0438	transferase activity, transferring glycosyl groups
L6483_RS23870	COG0521	Mo-molybdopterin cofactor biosynthetic process
L6483_RS23935	COG5002	protein histidine kinase activity
L6483_RS23945	COG2267	carboxylic ester hydrolase activity
L6483_RS23950	COG1368	sulfuric ester hydrolase activity
L6483_RS23965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L6483_RS23970	COG1116	anion transmembrane transporter activity
L6483_RS23975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L6483_RS24000	COG0494	nUDIX hydrolase
L6483_RS24030	COG0288	reversible hydration of carbon dioxide
L6483_RS24035	COG1271	oxidase subunit
L6483_RS24040	COG1294	oxidase, subunit
L6483_RS24060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS24085	COG1842	Phage shock protein A
L6483_RS24120	COG0745	RESPONSE REGULATOR receiver
L6483_RS24150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L6483_RS24155	COG1597	lipid kinase activity
L6483_RS24180	COG0586	Pfam SNARE associated Golgi protein
L6483_RS24190	COG4977	sequence-specific DNA binding
L6483_RS24200	COG0577	efflux transmembrane transporter activity
L6483_RS24205	COG1136	(ABC) transporter
L6483_RS24210	COG3708	Transcriptional regulator
L6483_RS24210	COG2207	Transcriptional regulator
L6483_RS24225	COG0745	RESPONSE REGULATOR receiver
L6483_RS24230	COG2205	protein histidine kinase activity
L6483_RS24235	COG0577	efflux transmembrane transporter activity
L6483_RS24240	COG0577	efflux transmembrane transporter activity
L6483_RS24245	COG1136	(ABC) transporter
L6483_RS24250	COG0577	efflux transmembrane transporter activity
L6483_RS24275	COG2188	Transcriptional regulator
L6483_RS24295	COG3964	amidohydrolase
L6483_RS24320	COG4948	Mandelate Racemase Muconate Lactonizing
L6483_RS24330	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L6483_RS24335	COG0596	Alpha beta hydrolase
L6483_RS24345	COG1169	isochorismate synthase
L6483_RS24350	COG1575	Belongs to the MenA family. Type 1 subfamily
L6483_RS24355	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L6483_RS24470	COG0058	SHG alpha-glucan phosphorylase activity
L6483_RS24480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L6483_RS24500	COG1404	Belongs to the peptidase S8 family
L6483_RS24515	COG1595	DNA-templated transcription, initiation
L6483_RS24610	COG0544	peptidyl-prolyl cis-trans isomerase activity
L6483_RS24645	COG1285	pathogenesis
L6483_RS24650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L6483_RS24665	COG2155	Conserved Protein
L6483_RS24670	COG1098	S1 RNA binding domain
L6483_RS24675	COG0436	Aminotransferase
L6483_RS24680	COG1522	sequence-specific DNA binding
L6483_RS24685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L6483_RS24690	COG2267	carboxylic ester hydrolase activity
L6483_RS24700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L6483_RS24720	COG5018	Exonuclease
L6483_RS24725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6483_RS24750	COG2050	protein possibly involved in aromatic compounds catabolism
L6483_RS24760	COG1268	BioY protein
L6483_RS24765	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L6483_RS24770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L6483_RS24785	COG3584	3D domain protein
L6483_RS24800	COG1252	NADH dehydrogenase
L6483_RS24810	COG3708	Transcriptional regulator
L6483_RS24825	COG1683	Conserved Protein
L6483_RS24835	COG0316	Belongs to the HesB IscA family
L6483_RS24850	COG1252	NADH dehydrogenase
L6483_RS24860	COG2274	protein secretion by the type I secretion system
L6483_RS24865	COG0390	transport system, permease component
L6483_RS24875	COG2824	Alkylphosphonate utilization operon protein PhnA
L6483_RS24895	COG4837	Protein of unknown function (DUF1462)
L6483_RS24900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L6483_RS24910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L6483_RS24915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L6483_RS24925	COG2249	NAD(P)H dehydrogenase (quinone) activity
L6483_RS24930	COG0647	UMP catabolic process
L6483_RS24940	COG2445	Protein of unknown function DUF86
L6483_RS24945	COG1494	fructose-1,6-bisphosphatase
L6483_RS24960	COG4470	Protein conserved in bacteria
L6483_RS24970	COG0789	Transcriptional regulator
L6483_RS24975	COG4377	Putative membrane peptidase family (DUF2324)
L6483_RS25000	COG0739	heme binding
L6483_RS25010	COG3377	Domain of unknown function (DUF1805)
L6483_RS25015	COG0737	Belongs to the 5'-nucleotidase family
L6483_RS25020	COG0719	Fe-S assembly protein
L6483_RS25025	COG0822	iron-sulfur transferase activity
L6483_RS25030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L6483_RS25035	COG0719	Fe-S assembly protein
L6483_RS25040	COG0396	ATPase activity
L6483_RS25045	COG1464	Belongs to the NlpA lipoprotein family
L6483_RS25050	COG1464	Belongs to the NlpA lipoprotein family
L6483_RS25055	COG2011	ABC-type metal ion transport system permease component
L6483_RS25070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L6483_RS25075	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L6483_RS25085	COG1393	Belongs to the ArsC family
L6483_RS25150	COG1396	sequence-specific DNA binding
L6483_RS25160	COG1309	transcriptional regulator
L6483_RS25165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L6483_RS25170	COG1960	acyl-CoA dehydrogenase activity
L6483_RS25175	COG0183	Belongs to the thiolase family
L6483_RS25180	COG1024	Enoyl-CoA hydratase
L6483_RS25180	COG1250	3-hydroxyacyl-CoA dehydrogenase
L6483_RS25190	COG1686	Belongs to the peptidase S11 family
L6483_RS25205	COG0011	TIGRFAM Protein of
L6483_RS25210	COG0840	transmembrane signaling receptor activity
L6483_RS25225	COG2814	Major facilitator Superfamily
L6483_RS25230	COG0531	amino acid
L6483_RS25255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L6483_RS25300	COG0586	Pfam SNARE associated Golgi protein
L6483_RS25310	COG1376	ErfK ybiS ycfS ynhG family protein
L6483_RS25315	COG0745	RESPONSE REGULATOR receiver
L6483_RS25320	COG5002	protein histidine kinase activity
L6483_RS25345	COG0840	transmembrane signaling receptor activity
L6483_RS25350	COG2151	metal-sulfur cluster biosynthetic enzyme
L6483_RS25355	COG3227	Zinc metalloprotease (Elastase)
L6483_RS25360	COG1741	Belongs to the pirin family
L6483_RS25375	COG0475	glutathione-regulated potassium exporter activity
L6483_RS25380	COG0490	domain, Protein
L6483_RS25385	COG1115	amino acid carrier protein
L6483_RS25390	COG0783	Belongs to the Dps family
L6483_RS25405	COG1611	Belongs to the LOG family
L6483_RS25420	COG2311	Membrane
L6483_RS25425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS25430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS25435	COG1115	amino acid carrier protein
L6483_RS25440	COG1115	amino acid carrier protein
L6483_RS25445	COG2910	NAD(P)H-binding
L6483_RS25470	COG0656	L-ascorbic acid biosynthetic process
L6483_RS25475	COG2814	Major facilitator Superfamily
L6483_RS25480	COG1733	regulation of RNA biosynthetic process
L6483_RS25490	COG1252	NADH dehydrogenase
L6483_RS25500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L6483_RS25515	COG3290	protein histidine kinase activity
L6483_RS25515	COG0840	transmembrane signaling receptor activity
L6483_RS25550	COG0488	(ABC) transporter
L6483_RS25555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L6483_RS25565	COG2814	Major facilitator Superfamily
L6483_RS25615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L6483_RS25620	COG0697	spore germination
L6483_RS25640	COG0557	exoribonuclease II activity
L6483_RS25645	COG1647	Serine aminopeptidase, S33
L6483_RS25650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L6483_RS25655	COG1346	cytolysis
L6483_RS25690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L6483_RS25705	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L6483_RS25730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6483_RS25745	COG2323	membrane
L6483_RS25755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L6483_RS25765	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L6483_RS25775	COG1051	belongs to the nudix hydrolase family
L6483_RS25785	COG0492	ferredoxin-NADP+ reductase activity
L6483_RS25790	COG0457	Tetratricopeptide repeat
L6483_RS25795	COG0110	maltose O-acetyltransferase activity
L6483_RS25815	COG1950	PFAM Membrane protein of
L6483_RS25825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L6483_RS25830	COG0556	nucleotide-excision repair
L6483_RS25845	COG0789	Transcriptional regulator
L6483_RS25870	COG2855	membrane
L6483_RS25875	COG0583	DNA-binding transcription factor activity
L6483_RS25885	COG0655	NAD(P)H dehydrogenase (quinone) activity
L6483_RS25890	COG0488	(ABC) transporter
L6483_RS25900	COG1132	(ABC) transporter
L6483_RS25910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6483_RS25915	COG0793	Belongs to the peptidase S41A family
L6483_RS25915	COG3409	Peptidoglycan-binding domain 1 protein
L6483_RS25920	COG2177	Part of the ABC transporter FtsEX involved in
L6483_RS25925	COG2884	Cell division ATP-binding protein ftsE
L6483_RS25945	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L6483_RS25950	COG1278	Cold shock
L6483_RS25955	COG1040	competence protein
L6483_RS25960	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L6483_RS25970	COG1733	regulation of RNA biosynthetic process
L6483_RS25975	COG1307	EDD domain protein, DegV family
L6483_RS25980	COG1739	Uncharacterized protein family UPF0029
L6483_RS25985	COG1316	TRANSCRIPTIONal
L6483_RS25990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L6483_RS25995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L6483_RS26000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L6483_RS26010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L6483_RS26010	COG3933	PFAM sigma-54 factor interaction domain-containing protein
L6483_RS26030	COG1486	melibiose metabolic process
L6483_RS26035	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6483_RS26040	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6483_RS26050	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L6483_RS26070	COG1447	Phosphotransferase system cellobiose-specific component IIA
L6483_RS26080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L6483_RS26085	COG1301	dicarboxylic acid transport
L6483_RS26095	COG0346	lactoylglutathione lyase activity
L6483_RS26115	COG1511	domain protein
L6483_RS26120	COG0583	DNA-binding transcription factor activity
L6483_RS26125	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
L6483_RS26135	COG1271	oxidase subunit
L6483_RS26140	COG1294	oxidase, subunit
L6483_RS26145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L6483_RS26180	COG1620	l-lactate permease
L6483_RS26190	COG2389	metal-binding protein
L6483_RS26200	COG1368	sulfuric ester hydrolase activity
L6483_RS26210	COG0791	NLP P60 protein
L6483_RS26210	COG1388	LysM domain
L6483_RS26215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L6483_RS26225	COG1215	transferase activity, transferring glycosyl groups
L6483_RS26235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6483_RS26240	COG3584	3D domain protein
L6483_RS26240	COG1388	LysM domain
L6483_RS26250	COG4715	Zinc finger, swim domain protein
L6483_RS26255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L6483_RS26300	COG0577	efflux transmembrane transporter activity
L6483_RS26305	COG1136	(ABC) transporter
L6483_RS26340	COG5002	protein histidine kinase activity
L6483_RS26345	COG0745	RESPONSE REGULATOR receiver
L6483_RS26350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L6483_RS26370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L6483_RS26380	COG0438	transferase activity, transferring glycosyl groups
L6483_RS26400	COG0438	transferase activity, transferring glycosyl groups
L6483_RS26405	COG0438	transferase activity, transferring glycosyl groups
L6483_RS26410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L6483_RS26415	COG0151	Belongs to the GarS family
L6483_RS26425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L6483_RS26435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L6483_RS26440	COG4464	protein tyrosine phosphatase activity
L6483_RS26445	COG0489	protein tyrosine kinase activity
L6483_RS26450	COG3944	biosynthesis protein
L6483_RS26455	COG0489	protein tyrosine kinase activity
L6483_RS26470	COG1609	Transcriptional regulator
L6483_RS26480	COG0739	heme binding
L6483_RS26495	COG3279	Response regulator of the LytR AlgR family
L6483_RS26500	COG2385	sporulation resulting in formation of a cellular spore
L6483_RS26515	COG4836	Membrane
L6483_RS26520	COG1007	ATP synthesis coupled electron transport
L6483_RS26530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L6483_RS26540	COG0839	Belongs to the complex I subunit 6 family
L6483_RS26560	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L6483_RS26575	COG5001	Diguanylate cyclase
L6483_RS26575	COG3300	MHYT domain
L6483_RS26625	COG0356	it plays a direct role in the translocation of protons across the membrane
L6483_RS26660	COG0698	ribose 5-phosphate isomerase
L6483_RS26670	COG2190	(PTS) system
L6483_RS26675	COG2259	Doxx family
L6483_RS26680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L6483_RS26700	COG0009	L-threonylcarbamoyladenylate synthase
L6483_RS26715	COG2890	protein-(glutamine-N5) methyltransferase activity
L6483_RS26735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L6483_RS26740	COG1494	fructose-1,6-bisphosphatase
L6483_RS26760	COG4821	SIS domain
L6483_RS26780	COG1960	acyl-CoA dehydrogenase activity
L6483_RS26785	COG1960	acyl-CoA dehydrogenase activity
L6483_RS26790	COG1250	3-hydroxyacyl-CoA dehydrogenase
L6483_RS26795	COG0183	Belongs to the thiolase family
L6483_RS26800	COG0247	lactate metabolic process
L6483_RS26800	COG2181	nitrate reductase activity
L6483_RS26805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L6483_RS26815	COG5001	Diguanylate cyclase
L6483_RS26815	COG3300	MHYT domain
L6483_RS26835	COG2197	response regulator
L6483_RS26840	COG4585	Histidine kinase
L6483_RS26845	COG0842	Transport permease protein
L6483_RS26850	COG1131	(ABC) transporter
L6483_RS26855	COG0024	Methionine aminopeptidase
L6483_RS26880	COG1595	DNA-templated transcription, initiation
L6483_RS26890	COG4506	Protein conserved in bacteria
L6483_RS26895	COG1619	proteins homologs of microcin C7 resistance protein MccF
L6483_RS26910	COG0010	Belongs to the arginase family
L6483_RS26920	COG2814	Major facilitator Superfamily
L6483_RS26925	COG0789	Transcriptional regulator
L6483_RS26930	COG0584	glycerophosphoryl diester phosphodiesterase
L6483_RS26935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L6483_RS26945	COG1994	Peptidase M50
L6483_RS26955	COG1078	dGTPase activity
L6483_RS26960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L6483_RS26965	COG1120	ATPase activity
L6483_RS26970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS26975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L6483_RS26995	COG0095	Lipoate-protein ligase
L6483_RS27000	COG0280	phosphate acetyltransferase
L6483_RS27015	COG3773	Cell wall hydrolase
L6483_RS27025	COG2363	Small membrane protein
L6483_RS27035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L6483_RS27040	COG2233	PERMEase
L6483_RS27045	COG0561	phosphatase activity
L6483_RS27050	COG2814	Major facilitator Superfamily
L6483_RS27060	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L6483_RS27065	COG1131	(ABC) transporter
L6483_RS27070	COG2755	lipolytic protein G-D-S-L family
L6483_RS27075	COG1609	Transcriptional regulator
L6483_RS27085	COG0460	homoserine dehydrogenase
L6483_RS27095	COG2873	o-acetylhomoserine
L6483_RS27100	COG1011	Hydrolase
L6483_RS27105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L6483_RS27115	COG2197	response regulator
L6483_RS27120	COG4585	Histidine kinase
L6483_RS27120	COG2203	Gaf domain
L6483_RS27125	COG0351	phosphomethylpyrimidine kinase
L6483_RS27130	COG3706	GGDEF domain
L6483_RS27135	COG2879	small protein
L6483_RS27140	COG1966	Carbon starvation protein
L6483_RS27145	COG3279	Response regulator of the LytR AlgR family
L6483_RS27150	COG0477	Major facilitator Superfamily
L6483_RS27175	COG0840	transmembrane signaling receptor activity
L6483_RS27185	COG1607	acyl-coa hydrolase
L6483_RS27190	COG1216	Glycosyl transferase, family 2
L6483_RS27200	COG0488	(ABC) transporter
L6483_RS27220	COG0463	Glycosyl transferase, family 2
L6483_RS27225	COG1309	transcriptional regulator
L6483_RS27230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L6483_RS27235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6483_RS27235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L6483_RS27240	COG0628	permease
L6483_RS27255	COG3279	Response regulator of the LytR AlgR family
L6483_RS27260	COG3275	phosphorelay sensor kinase activity
L6483_RS27265	COG2814	Major facilitator Superfamily
L6483_RS27270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L6483_RS27275	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
L6483_RS27280	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L6483_RS27330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L6483_RS27335	COG1272	protein, Hemolysin III
L6483_RS27365	COG1164	Oligoendopeptidase f
L6483_RS27375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L6483_RS27405	COG4974	Belongs to the 'phage' integrase family
L6483_RS27470	COG1196	nuclear chromosome segregation
L6483_RS27490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L6483_RS27495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L6483_RS27500	COG4853	Protein conserved in bacteria
L6483_RS27505	COG4863	YycH protein
L6483_RS27510	COG5002	protein histidine kinase activity
L6483_RS27515	COG0745	RESPONSE REGULATOR receiver
L6483_RS27545	COG0305	Participates in initiation and elongation during chromosome replication
L6483_RS27555	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L6483_RS27560	COG4241	membrane
L6483_RS27570	COG0629	single-stranded DNA binding
L6483_RS27580	COG0012	GTP binding
L6483_RS27585	COG4481	Protein conserved in bacteria
L6483_RS27590	COG0668	transmembrane transport
L6483_RS27600	COG1475	DNA binding
L6483_RS27605	COG1192	Involved in chromosome partitioning
L6483_RS27630	COG1847	R3H domain protein
L6483_RS27635	COG0706	membrane insertase activity
L6483_RS27645	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L6483_RS27980	COG1609	Transcriptional regulator
L6483_RS27985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L6483_RS27985	COG1263	PTS System
L6483_RS27990	COG1621	beta-fructofuranosidase activity
L6483_RS27995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L6483_RS28025	COG2311	Membrane
L6483_RS28055	COG0776	regulation of translation
L6483_RS28095	COG2002	toxin-antitoxin pair type II binding
L6483_RS28130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L6483_RS28200	COG0789	Transcriptional regulator
L6483_RS28255	COG0697	spore germination
L6483_RS28280	COG2323	membrane
L6483_RS28295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L6483_RS28335	COG0860	N-Acetylmuramoyl-L-alanine amidase
L6483_RS28350	COG3708	Transcriptional regulator
L6483_RS28350	COG2207	Transcriptional regulator
L6483_RS28390	COG1733	regulation of RNA biosynthetic process
L6483_RS28400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L6483_RS28410	COG1181	Belongs to the D-alanine--D-alanine ligase family
L6483_RS28410	COG2918	glutathione biosynthetic process
L6483_RS28440	COG1335	isochorismatase
L6483_RS28445	COG4990	cell redox homeostasis
L6483_RS28450	COG0745	RESPONSE REGULATOR receiver
L6483_RS28485	COG4974	Belongs to the 'phage' integrase family
L6483_RS28500	COG0457	Tetratricopeptide repeat
L6483_RS28620	COG3344	reverse transcriptase
L6483_RS28640	COG3344	reverse transcriptase
L6483_RS28700	COG1396	sequence-specific DNA binding
L6483_RS28735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L6483_RS28740	COG0582	viral genome integration into host DNA
L6483_RS28770	COG2003	Belongs to the UPF0758 family
L6483_RS28785	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L6483_RS28850	COG3397	chitin binding
L6483_RS28885	COG0791	NLP P60 protein
L6483_RS28885	COG1388	LysM domain
L6483_RS28885	COG3103	Sh3 type 3 domain protein
L6483_RS28930	COG0640	Transcriptional regulator