locus-tag	class	description
L7754_RS00010	COG0454	-acetyltransferase
L7754_RS00030	COG0328	RNA-DNA hybrid ribonuclease activity
L7754_RS00065	COG3403	YqcI/YcgG family
L7754_RS00070	COG1280	lysine exporter protein (LysE YggA)
L7754_RS00090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L7754_RS00095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L7754_RS00105	COG0475	glutathione-regulated potassium exporter activity
L7754_RS00110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L7754_RS00115	COG4978	Transcriptional regulator
L7754_RS00115	COG0789	Transcriptional regulator
L7754_RS00125	COG2323	membrane
L7754_RS00130	COG1434	Gram-negative-bacterium-type cell wall biogenesis
L7754_RS00165	COG1923	regulation of RNA biosynthetic process
L7754_RS00175	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L7754_RS00180	COG1360	Flagellar Motor Protein
L7754_RS00185	COG2201	protein-glutamate methylesterase activity
L7754_RS00190	COG2198	Histidine kinase
L7754_RS00190	COG0643	Histidine kinase
L7754_RS00195	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L7754_RS00195	COG1776	CheC inhibitor of MCP methylation
L7754_RS00210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L7754_RS00230	COG1256	bacterial-type flagellum assembly
L7754_RS00235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L7754_RS00255	COG1815	bacterial-type flagellum-dependent cell motility
L7754_RS00260	COG1558	bacterial-type flagellum-dependent cell motility
L7754_RS00270	COG1766	The M ring may be actively involved in energy transduction
L7754_RS00275	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L7754_RS00285	COG1157	protein secretion by the type III secretion system
L7754_RS00305	COG1749	Flagellar hook protein flgE
L7754_RS00320	COG0835	chemotaxis
L7754_RS00320	COG0784	Response regulator, receiver
L7754_RS00330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
L7754_RS00340	COG0741	lytic transglycosylase activity
L7754_RS00350	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L7754_RS00355	COG1776	CheC inhibitor of MCP methylation
L7754_RS00355	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
L7754_RS00365	COG1338	Plays a role in the flagellum-specific transport system
L7754_RS00370	COG1987	bacterial-type flagellum assembly
L7754_RS00380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L7754_RS00385	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
L7754_RS00390	COG1419	protein localization to endoplasmic reticulum
L7754_RS00395	COG4786	Flagellar basal body rod
L7754_RS00400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L7754_RS00435	COG2329	Antibiotic biosynthesis monooxygenase
L7754_RS00460	COG0583	DNA-binding transcription factor activity
L7754_RS00470	COG0725	ABC transporter, periplasmic molybdate-binding protein
L7754_RS00510	COG0406	alpha-ribazole phosphatase activity
L7754_RS00540	COG0367	asparagine synthase
L7754_RS00570	COG1802	Transcriptional regulator
L7754_RS00575	COG0697	spore germination
L7754_RS00585	COG0523	cobalamin synthesis protein
L7754_RS00590	COG0701	Predicted permease
L7754_RS00605	COG1757	Na H antiporter
L7754_RS00610	COG0789	Transcriptional regulator
L7754_RS00635	COG0534	Mate efflux family protein
L7754_RS00640	COG3340	Belongs to the peptidase S51 family
L7754_RS00660	COG0785	Cytochrome C biogenesis protein
L7754_RS00665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L7754_RS00680	COG0457	Tetratricopeptide repeat
L7754_RS00700	COG2733	membrane
L7754_RS00735	COG1131	(ABC) transporter
L7754_RS00750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L7754_RS00755	COG0528	UMP kinase activity
L7754_RS00770	COG1027	Aspartate ammonia-lyase
L7754_RS00775	COG0281	malic enzyme
L7754_RS00780	COG4191	Histidine kinase
L7754_RS00785	COG0784	Response regulator, receiver
L7754_RS00790	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L7754_RS00835	COG2814	Major facilitator Superfamily
L7754_RS00850	COG1695	Transcriptional regulator
L7754_RS00860	COG0477	Major facilitator Superfamily
L7754_RS00875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L7754_RS00880	COG2223	nitrite transmembrane transporter activity
L7754_RS00885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L7754_RS00905	COG0733	neurotransmitter:sodium symporter activity
L7754_RS00915	COG5566	PFAM Mor transcription activator
L7754_RS00920	COG2323	membrane
L7754_RS00940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L7754_RS00950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L7754_RS00955	COG0028	Belongs to the TPP enzyme family
L7754_RS00975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L7754_RS01000	COG2814	Major facilitator Superfamily
L7754_RS01005	COG3384	dioxygenase
L7754_RS01015	COG3279	Response regulator of the LytR AlgR family
L7754_RS01020	COG0427	acetyl-CoA hydrolase
L7754_RS01040	COG4166	transmembrane transport
L7754_RS01065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS01085	COG1914	H( )-stimulated, divalent metal cation uptake system
L7754_RS01100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L7754_RS01105	COG0531	amino acid
L7754_RS01130	COG2309	aminopeptidase activity
L7754_RS01145	COG0456	acetyltransferase
L7754_RS01160	COG1309	transcriptional regulator
L7754_RS01165	COG2390	Transcriptional regulator
L7754_RS01175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS01180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L7754_RS01190	COG4846	Membrane protein involved in cytochrome C biogenesis
L7754_RS01200	COG0006	proline dipeptidase activity
L7754_RS01210	COG2132	Multicopper oxidase
L7754_RS01220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L7754_RS01240	COG1114	Component of the transport system for branched-chain amino acids
L7754_RS01250	COG2372	response to copper ion
L7754_RS01250	COG1276	copper resistance
L7754_RS01255	COG4549	nuclear export factor GLE1
L7754_RS01260	COG0697	spore germination
L7754_RS01265	COG0583	DNA-binding transcription factor activity
L7754_RS01270	COG1959	2 iron, 2 sulfur cluster binding
L7754_RS01275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L7754_RS01280	COG0778	Nitroreductase
L7754_RS01290	COG0628	permease
L7754_RS01300	COG1231	oxidoreductase activity
L7754_RS01305	COG0523	cobalamin synthesis protein
L7754_RS01315	COG0411	ABC transporter
L7754_RS01335	COG0583	DNA-binding transcription factor activity
L7754_RS01365	COG1271	oxidase subunit
L7754_RS01370	COG1294	oxidase, subunit
L7754_RS01375	COG4988	ABC transporter
L7754_RS01380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
L7754_RS01390	COG1216	Glycosyl transferase, family 2
L7754_RS01430	COG1686	Belongs to the peptidase S11 family
L7754_RS01445	COG0791	NLP P60 protein
L7754_RS01445	COG1388	LysM domain
L7754_RS01455	COG1132	(ABC) transporter
L7754_RS01460	COG0745	RESPONSE REGULATOR receiver
L7754_RS01465	COG5002	protein histidine kinase activity
L7754_RS01475	COG0300	oxidoreductase activity
L7754_RS01505	COG0460	homoserine dehydrogenase
L7754_RS01530	COG1316	TRANSCRIPTIONal
L7754_RS01540	COG0745	RESPONSE REGULATOR receiver
L7754_RS01545	COG5002	protein histidine kinase activity
L7754_RS01560	COG1285	pathogenesis
L7754_RS01565	COG1247	-acetyltransferase
L7754_RS01585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L7754_RS01595	COG1082	Xylose isomerase domain protein TIM barrel
L7754_RS01605	COG2814	Major facilitator Superfamily
L7754_RS01610	COG1279	arginine transmembrane transporter activity
L7754_RS01615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS01625	COG1752	Esterase of the alpha-beta hydrolase superfamily
L7754_RS01660	COG0577	efflux transmembrane transporter activity
L7754_RS01665	COG2002	toxin-antitoxin pair type II binding
L7754_RS01670	COG1404	Belongs to the peptidase S8 family
L7754_RS01675	COG0640	Transcriptional regulator
L7754_RS01680	COG0667	Aldo Keto reductase
L7754_RS01685	COG2814	Major facilitator Superfamily
L7754_RS01690	COG3152	Membrane
L7754_RS01715	COG0840	transmembrane signaling receptor activity
L7754_RS01730	COG3949	Membrane
L7754_RS01735	COG0783	Belongs to the Dps family
L7754_RS01750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L7754_RS01760	COG1231	oxidoreductase activity
L7754_RS01765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS01770	COG4989	oxidoreductase activity
L7754_RS01775	COG0523	cobalamin synthesis protein
L7754_RS01780	COG0456	acetyltransferase
L7754_RS01785	COG0803	Belongs to the bacterial solute-binding protein 9 family
L7754_RS01795	COG0702	epimerase
L7754_RS01805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L7754_RS01815	COG4166	transmembrane transport
L7754_RS01840	COG5337	Spore coat protein CotH
L7754_RS01845	COG1051	belongs to the nudix hydrolase family
L7754_RS01850	COG0586	Pfam SNARE associated Golgi protein
L7754_RS01855	COG2244	polysaccharide biosynthetic process
L7754_RS01865	COG0701	Predicted permease
L7754_RS01870	COG3689	TIGRFAM TIGR03943 family protein
L7754_RS01880	COG1607	acyl-coa hydrolase
L7754_RS01890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L7754_RS01905	COG0702	epimerase
L7754_RS01910	COG2839	Protein conserved in bacteria
L7754_RS01915	COG1253	flavin adenine dinucleotide binding
L7754_RS01930	COG1114	Component of the transport system for branched-chain amino acids
L7754_RS01935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L7754_RS01955	COG0860	N-Acetylmuramoyl-L-alanine amidase
L7754_RS01965	COG1876	peptidase activity
L7754_RS01975	COG0154	amidase activity
L7754_RS01980	COG2211	Major facilitator Superfamily
L7754_RS01995	COG0860	N-Acetylmuramoyl-L-alanine amidase
L7754_RS02005	COG0561	phosphatase activity
L7754_RS02020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L7754_RS02040	COG1819	glycosyl
L7754_RS02045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS02080	COG0456	acetyltransferase
L7754_RS02115	COG4499	WXG100 protein secretion system (Wss), protein YukC
L7754_RS02235	COG3874	Sporulation protein YtfJ
L7754_RS02260	COG2226	methyltransferase
L7754_RS02285	COG0346	lactoylglutathione lyase activity
L7754_RS02295	COG0604	alcohol dehydrogenase
L7754_RS02300	COG1595	DNA-templated transcription, initiation
L7754_RS02310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L7754_RS02320	COG0426	domain, Protein
L7754_RS02320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L7754_RS02330	COG0386	Belongs to the glutathione peroxidase family
L7754_RS02335	COG1305	Transglutaminase-like
L7754_RS02340	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
L7754_RS02345	COG0714	Associated with various cellular activities
L7754_RS02350	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
L7754_RS02355	COG1140	nitrate reductase beta subunit
L7754_RS02360	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
L7754_RS02365	COG2181	nitrate reductase activity
L7754_RS02370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L7754_RS02375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L7754_RS02380	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L7754_RS02385	COG0303	'Molybdopterin
L7754_RS02390	COG0314	molybdopterin synthase activity
L7754_RS02400	COG2223	nitrite transmembrane transporter activity
L7754_RS02420	COG1648	precorrin-2 dehydrogenase activity
L7754_RS02430	COG1587	Uroporphyrinogen-III synthase
L7754_RS02430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L7754_RS02435	COG2146	nitrite reductase [NAD(P)H] activity
L7754_RS02440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L7754_RS02445	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
L7754_RS02480	COG2359	stage V sporulation protein S
L7754_RS02510	COG4974	Belongs to the 'phage' integrase family
L7754_RS02535	COG0457	Tetratricopeptide repeat
L7754_RS02550	COG1418	mRNA catabolic process
L7754_RS02555	COG0488	(ABC) transporter
L7754_RS02570	COG0629	single-stranded DNA binding
L7754_RS02575	COG1413	lyase activity
L7754_RS02590	COG2521	methyltransferase
L7754_RS02590	COG2136	Putative SAM-dependent methyltransferase
L7754_RS02595	COG0018	arginyl-trna synthetase
L7754_RS02635	COG0017	Asparaginyl-tRNA synthetase
L7754_RS02640	COG1929	Belongs to the glycerate kinase type-1 family
L7754_RS02650	COG0745	RESPONSE REGULATOR receiver
L7754_RS02655	COG5002	protein histidine kinase activity
L7754_RS02655	COG3850	Histidine kinase
L7754_RS02670	COG0733	neurotransmitter:sodium symporter activity
L7754_RS02695	COG2610	gluconate transmembrane transporter activity
L7754_RS02705	COG1794	racemase activity, acting on amino acids and derivatives
L7754_RS02715	COG0456	acetyltransferase
L7754_RS02725	COG3655	Transcriptional regulator
L7754_RS02730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L7754_RS02740	COG1131	(ABC) transporter
L7754_RS02745	COG4473	ABC transporter
L7754_RS02755	COG0546	phosphoglycolate phosphatase activity
L7754_RS02770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L7754_RS02785	COG0768	penicillin binding
L7754_RS02795	COG0204	Acyl-transferase
L7754_RS02800	COG1272	protein, Hemolysin III
L7754_RS02810	COG0805	protein transport
L7754_RS02820	COG1307	EDD domain protein, DegV family
L7754_RS02830	COG1999	signal sequence binding
L7754_RS02835	COG0071	Belongs to the small heat shock protein (HSP20) family
L7754_RS02840	COG0367	asparagine synthase
L7754_RS02855	COG0860	N-Acetylmuramoyl-L-alanine amidase
L7754_RS02860	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS02865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L7754_RS02880	COG1335	isochorismatase
L7754_RS02890	COG0668	transmembrane transport
L7754_RS02895	COG2203	Gaf domain
L7754_RS02895	COG4585	Histidine kinase
L7754_RS02900	COG2197	response regulator
L7754_RS02905	COG1737	Transcriptional regulator
L7754_RS02910	COG0384	phenazine biosynthesis protein PhzF
L7754_RS02915	COG1064	alcohol dehydrogenase
L7754_RS02940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L7754_RS02975	COG1125	glycine betaine transport
L7754_RS02975	COG0517	IMP dehydrogenase activity
L7754_RS02980	COG1174	glycine betaine transport
L7754_RS03015	COG1253	flavin adenine dinucleotide binding
L7754_RS03020	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS03025	COG5506	Protein of unknown function (DUF1694)
L7754_RS03040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L7754_RS03045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L7754_RS03050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L7754_RS03055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L7754_RS03060	COG0456	acetyltransferase
L7754_RS03065	COG3829	transcription factor binding
L7754_RS03070	COG1509	lysine 2,3-aminomutase activity
L7754_RS03105	COG4991	sh3 domain protein
L7754_RS03105	COG0515	serine threonine protein kinase
L7754_RS03105	COG3064	Membrane
L7754_RS03115	COG0671	phosphoesterase, PA-phosphatase related
L7754_RS03120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L7754_RS03125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L7754_RS03210	COG0300	oxidoreductase activity
L7754_RS03230	COG4499	WXG100 protein secretion system (Wss), protein YukC
L7754_RS03230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L7754_RS03240	COG2814	Major facilitator Superfamily
L7754_RS03245	COG4841	protein insertion into membrane
L7754_RS03250	COG0372	Belongs to the citrate synthase family
L7754_RS03255	COG2079	MmgE PrpD family protein
L7754_RS03260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
L7754_RS03265	COG1960	acyl-CoA dehydrogenase activity
L7754_RS03270	COG2084	Dehydrogenase
L7754_RS03280	COG1280	lysine exporter protein (LysE YggA)
L7754_RS03285	COG1024	Enoyl-CoA hydratase
L7754_RS03300	COG0420	3'-5' exonuclease activity
L7754_RS03305	COG0419	ATPase involved in DNA repair
L7754_RS03330	COG2223	nitrite transmembrane transporter activity
L7754_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS03340	COG1169	isochorismate synthase
L7754_RS03345	COG1021	2,3-dihydroxybenzoate-AMP ligase
L7754_RS03350	COG1535	isochorismatase
L7754_RS03350	COG3433	isochorismatase activity
L7754_RS03355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L7754_RS03360	COG3251	PFAM MbtH domain protein
L7754_RS03365	COG2814	Major facilitator Superfamily
L7754_RS03380	COG0776	regulation of translation
L7754_RS03390	COG2318	DinB family
L7754_RS03400	COG1115	amino acid carrier protein
L7754_RS03420	COG1187	pseudouridine synthase activity
L7754_RS03425	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L7754_RS03430	COG1136	(ABC) transporter
L7754_RS03470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L7754_RS03490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS03520	COG1247	-acetyltransferase
L7754_RS03545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L7754_RS03555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS03585	COG0583	DNA-binding transcription factor activity
L7754_RS03590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L7754_RS03610	COG0583	DNA-binding transcription factor activity
L7754_RS03615	COG2258	MOSC domain
L7754_RS03630	COG1132	(ABC) transporter
L7754_RS03635	COG1132	(ABC) transporter
L7754_RS03660	COG1396	sequence-specific DNA binding
L7754_RS03690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L7754_RS03695	COG1595	DNA-templated transcription, initiation
L7754_RS03725	COG1649	PFAM Uncharacterised BCR, COG1649
L7754_RS03750	COG2971	BadF BadG BcrA BcrD
L7754_RS03760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L7754_RS03770	COG1846	Transcriptional regulator
L7754_RS03790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS03810	COG1309	transcriptional regulator
L7754_RS03830	COG3615	Tellurite resistance protein tehB
L7754_RS03830	COG0500	methyltransferase
L7754_RS03840	COG2226	methyltransferase
L7754_RS03845	COG3961	Belongs to the TPP enzyme family
L7754_RS03850	COG1846	Transcriptional regulator
L7754_RS03880	COG2195	Cleaves the N-terminal amino acid of tripeptides
L7754_RS03905	COG2002	toxin-antitoxin pair type II binding
L7754_RS03915	COG0730	response to heat
L7754_RS03920	COG0110	maltose O-acetyltransferase activity
L7754_RS03925	COG1686	Belongs to the peptidase S11 family
L7754_RS03940	COG2814	Major facilitator Superfamily
L7754_RS03975	COG2312	Erythromycin esterase
L7754_RS03985	COG0741	lytic transglycosylase activity
L7754_RS03990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS04030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L7754_RS04035	COG0768	penicillin binding
L7754_RS04040	COG1595	DNA-templated transcription, initiation
L7754_RS04050	COG0768	penicillin binding
L7754_RS04055	COG0768	penicillin binding
L7754_RS04065	COG1408	metallophosphoesterase
L7754_RS04075	COG1131	(ABC) transporter
L7754_RS04085	COG1309	transcriptional regulator
L7754_RS04100	COG1960	acyl-CoA dehydrogenase activity
L7754_RS04105	COG0439	Biotin carboxylase
L7754_RS04110	COG0511	ligase activity, forming carbon-carbon bonds
L7754_RS04115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L7754_RS04120	COG1024	Enoyl-CoA hydratase
L7754_RS04125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L7754_RS04130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L7754_RS04165	COG1686	Belongs to the peptidase S11 family
L7754_RS04190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L7754_RS04205	COG3227	Zinc metalloprotease (Elastase)
L7754_RS04210	COG2207	Transcriptional regulator
L7754_RS04240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L7754_RS04250	COG2814	Major facilitator Superfamily
L7754_RS04255	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS04260	COG1733	regulation of RNA biosynthetic process
L7754_RS04305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS04330	COG1063	alcohol dehydrogenase
L7754_RS04340	COG2323	membrane
L7754_RS04345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L7754_RS04355	COG3386	PFAM SMP-30 Gluconolaconase
L7754_RS04365	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
L7754_RS04370	COG3773	Cell wall hydrolase
L7754_RS04380	COG0745	RESPONSE REGULATOR receiver
L7754_RS04385	COG2205	protein histidine kinase activity
L7754_RS04395	COG0488	(ABC) transporter
L7754_RS04405	COG1136	(ABC) transporter
L7754_RS04410	COG0577	efflux transmembrane transporter activity
L7754_RS04430	COG0460	homoserine dehydrogenase
L7754_RS04435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS04445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L7754_RS04500	COG2124	cytochrome p450
L7754_RS04545	COG0561	phosphatase activity
L7754_RS04550	COG5002	protein histidine kinase activity
L7754_RS04555	COG0768	penicillin binding
L7754_RS04565	COG1819	glycosyl
L7754_RS04570	COG1794	racemase activity, acting on amino acids and derivatives
L7754_RS04595	COG2205	protein histidine kinase activity
L7754_RS04655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L7754_RS04660	COG0604	alcohol dehydrogenase
L7754_RS04665	COG0671	phosphoesterase, PA-phosphatase related
L7754_RS04670	COG0768	penicillin binding
L7754_RS04720	COG2814	Major facilitator Superfamily
L7754_RS04735	COG0584	glycerophosphoryl diester phosphodiesterase
L7754_RS04755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS04760	COG0697	spore germination
L7754_RS04795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L7754_RS04805	COG2223	nitrite transmembrane transporter activity
L7754_RS04825	COG0592	DNA-directed DNA polymerase activity
L7754_RS04845	COG0251	oxidation-reduction process
L7754_RS04850	COG3878	Protein conserved in bacteria
L7754_RS04870	COG4667	esterase of the alpha-beta hydrolase superfamily
L7754_RS04910	COG0322	excinuclease ABC activity
L7754_RS04940	COG1131	(ABC) transporter
L7754_RS04960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L7754_RS04995	COG1011	Hydrolase
L7754_RS05010	COG1073	alpha beta
L7754_RS05015	COG1523	belongs to the glycosyl hydrolase 13 family
L7754_RS05020	COG3227	Zinc metalloprotease (Elastase)
L7754_RS05025	COG0737	Belongs to the 5'-nucleotidase family
L7754_RS05045	COG0201	protein transport
L7754_RS05050	COG0697	spore germination
L7754_RS05055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS05060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L7754_RS05090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS05105	COG2959	enzyme of heme biosynthesis
L7754_RS05145	COG1309	transcriptional regulator
L7754_RS05165	COG3284	Transcriptional regulator
L7754_RS05180	COG1349	DNA-binding transcription factor activity
L7754_RS05195	COG1959	2 iron, 2 sulfur cluster binding
L7754_RS05210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L7754_RS05215	COG0508	dehydrogenase complex catalyzes the overall conversion of
L7754_RS05220	COG0022	dehydrogenase e1 component
L7754_RS05225	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L7754_RS05240	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS05270	COG4176	ABC-type proline glycine betaine transport system permease component
L7754_RS05275	COG0517	IMP dehydrogenase activity
L7754_RS05275	COG4175	Glycine betaine
L7754_RS05305	COG2153	protein acetylation
L7754_RS05310	COG3397	chitin binding
L7754_RS05315	COG1819	glycosyl
L7754_RS05335	COG2205	protein histidine kinase activity
L7754_RS05340	COG2226	methyltransferase
L7754_RS05345	COG2315	Protein conserved in bacteria
L7754_RS05390	COG3973	AAA domain
L7754_RS05405	COG0514	ATP-dependent DNA helicase (RecQ)
L7754_RS05440	COG4637	Psort location Cytoplasmic, score
L7754_RS05455	COG3397	chitin binding
L7754_RS05470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L7754_RS05475	COG1115	amino acid carrier protein
L7754_RS05480	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS05485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L7754_RS05495	COG3938	Belongs to the proline racemase family
L7754_RS05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L7754_RS05540	COG1078	dGTPase activity
L7754_RS05545	COG0586	Pfam SNARE associated Golgi protein
L7754_RS05555	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L7754_RS05565	COG4166	transmembrane transport
L7754_RS05575	COG4948	Mandelate Racemase Muconate Lactonizing
L7754_RS05590	COG0667	Aldo Keto reductase
L7754_RS05635	COG5002	protein histidine kinase activity
L7754_RS05635	COG3850	Histidine kinase
L7754_RS05640	COG0745	RESPONSE REGULATOR receiver
L7754_RS05680	COG1164	Oligoendopeptidase f
L7754_RS05685	COG1307	EDD domain protein, DegV family
L7754_RS05725	COG2814	Major facilitator Superfamily
L7754_RS05735	COG1664	Polymer-forming cytoskeletal
L7754_RS05740	COG0789	Transcriptional regulator
L7754_RS05745	COG4533	DNA binding
L7754_RS05750	COG2814	Major facilitator Superfamily
L7754_RS05750	COG0477	Major facilitator Superfamily
L7754_RS05770	COG2261	transglycosylase associated protein
L7754_RS05785	COG2226	methyltransferase
L7754_RS05820	COG0436	Aminotransferase
L7754_RS05825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
L7754_RS05875	COG0628	permease
L7754_RS05890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L7754_RS05895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L7754_RS05900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L7754_RS05940	COG2746	aminoglycoside 3-N-acetyltransferase activity
L7754_RS05950	COG0697	spore germination
L7754_RS05955	COG2318	DinB family
L7754_RS05975	COG4912	Dna alkylation repair
L7754_RS05980	COG0346	lactoylglutathione lyase activity
L7754_RS05985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS06000	COG0861	Integral membrane protein TerC family
L7754_RS06005	COG1368	sulfuric ester hydrolase activity
L7754_RS06010	COG0488	(ABC) transporter
L7754_RS06015	COG2409	Drug exporters of the RND superfamily
L7754_RS06015	COG1033	growth of symbiont in host cell
L7754_RS06020	COG1309	transcriptional regulator
L7754_RS06035	COG0287	Prephenate dehydrogenase
L7754_RS06050	COG1605	Chorismate mutase
L7754_RS06050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L7754_RS06095	COG1388	LysM domain
L7754_RS06095	COG3584	3D domain protein
L7754_RS06110	COG0346	lactoylglutathione lyase activity
L7754_RS06125	COG1309	transcriptional regulator
L7754_RS06140	COG1879	ABC-type sugar transport system periplasmic component
L7754_RS06145	COG1172	Belongs to the binding-protein-dependent transport system permease family
L7754_RS06150	COG1172	Belongs to the binding-protein-dependent transport system permease family
L7754_RS06160	COG2390	Transcriptional regulator
L7754_RS06165	COG1070	Carbohydrate kinase
L7754_RS06185	COG2329	Antibiotic biosynthesis monooxygenase
L7754_RS06205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS06220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L7754_RS06225	COG4187	Peptidase family M20/M25/M40
L7754_RS06230	COG1414	Transcriptional regulator
L7754_RS06235	COG0833	amino acid
L7754_RS06245	COG3239	Fatty acid desaturase
L7754_RS06255	COG2720	vancomycin resistance protein
L7754_RS06260	COG1785	Belongs to the alkaline phosphatase family
L7754_RS06270	COG3655	Transcriptional regulator
L7754_RS06290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS06295	COG0346	lactoylglutathione lyase activity
L7754_RS06320	COG0714	Associated with various cellular activities
L7754_RS06345	COG0463	Glycosyl transferase, family 2
L7754_RS06375	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L7754_RS06380	COG0753	catalase activity
L7754_RS06420	COG0714	Associated with various cellular activities
L7754_RS06525	COG0778	Nitroreductase
L7754_RS06530	COG1846	Transcriptional regulator
L7754_RS06550	COG3831	ATPase activity
L7754_RS06550	COG4884	unkown
L7754_RS06565	COG1136	(ABC) transporter
L7754_RS06595	COG0456	acetyltransferase
L7754_RS06610	COG0697	spore germination
L7754_RS06615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS06660	COG0730	response to heat
L7754_RS06670	COG0833	amino acid
L7754_RS06680	COG4335	DNA alkylation repair
L7754_RS06715	COG0768	penicillin binding
L7754_RS06745	COG1984	allophanate hydrolase subunit 2
L7754_RS06750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
L7754_RS06755	COG1414	Transcriptional regulator
L7754_RS06765	COG3142	Participates in the control of copper homeostasis
L7754_RS06770	COG0640	Transcriptional regulator
L7754_RS06780	COG1960	acyl-CoA dehydrogenase activity
L7754_RS06795	COG3314	Sporulation integral membrane protein YlbJ
L7754_RS06840	COG0574	Belongs to the PEP-utilizing enzyme family
L7754_RS06840	COG3848	Pyruvate phosphate dikinase
L7754_RS06845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS06865	COG1063	alcohol dehydrogenase
L7754_RS06875	COG1027	Aspartate ammonia-lyase
L7754_RS06880	COG0252	asparaginase activity
L7754_RS06885	COG1396	sequence-specific DNA binding
L7754_RS06915	COG5002	protein histidine kinase activity
L7754_RS06940	COG2207	Transcriptional regulator
L7754_RS06955	COG0322	excinuclease ABC activity
L7754_RS06960	COG0531	amino acid
L7754_RS06975	COG0531	amino acid
L7754_RS06980	COG0697	spore germination
L7754_RS06985	COG0784	Response regulator, receiver
L7754_RS06990	COG4191	Histidine kinase
L7754_RS06995	COG2066	Belongs to the glutaminase family
L7754_RS07000	COG1115	amino acid carrier protein
L7754_RS07010	COG2124	cytochrome p450
L7754_RS07025	COG0737	Belongs to the 5'-nucleotidase family
L7754_RS07030	COG2267	carboxylic ester hydrolase activity
L7754_RS07035	COG1335	isochorismatase
L7754_RS07055	COG0583	DNA-binding transcription factor activity
L7754_RS07060	COG1846	Transcriptional regulator
L7754_RS07065	COG0598	Magnesium transport protein CorA
L7754_RS07085	COG1073	alpha beta
L7754_RS07105	COG0415	Belongs to the DNA photolyase family
L7754_RS07120	COG0288	reversible hydration of carbon dioxide
L7754_RS07130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L7754_RS07135	COG5609	conserved protein (DUF2294)
L7754_RS07150	COG0697	spore germination
L7754_RS07160	COG0456	acetyltransferase
L7754_RS07165	COG1575	Belongs to the MenA family. Type 1 subfamily
L7754_RS07190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS07200	COG3347	Dehydrogenase
L7754_RS07200	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS07210	COG1070	Carbohydrate kinase
L7754_RS07215	COG0235	Class ii aldolase
L7754_RS07225	COG1172	Belongs to the binding-protein-dependent transport system permease family
L7754_RS07235	COG4154	Belongs to the RbsD FucU family
L7754_RS07250	COG0798	PFAM Bile acid sodium symporter
L7754_RS07255	COG0346	lactoylglutathione lyase activity
L7754_RS07260	COG0640	Transcriptional regulator
L7754_RS07270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L7754_RS07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L7754_RS07275	COG3320	Male sterility
L7754_RS07280	COG1309	transcriptional regulator
L7754_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS07290	COG1522	sequence-specific DNA binding
L7754_RS07315	COG0346	lactoylglutathione lyase activity
L7754_RS07355	COG1309	transcriptional regulator
L7754_RS07410	COG0745	RESPONSE REGULATOR receiver
L7754_RS07415	COG5002	protein histidine kinase activity
L7754_RS07415	COG3850	Histidine kinase
L7754_RS07465	COG2814	Major facilitator Superfamily
L7754_RS07485	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L7754_RS07500	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
L7754_RS07520	COG0577	efflux transmembrane transporter activity
L7754_RS07540	COG5002	protein histidine kinase activity
L7754_RS07540	COG3850	Histidine kinase
L7754_RS07550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS07575	COG1619	proteins homologs of microcin C7 resistance protein MccF
L7754_RS07595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L7754_RS07615	COG0662	Cupin 2, conserved barrel domain protein
L7754_RS07620	COG2207	Transcriptional regulator
L7754_RS07620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS07640	COG3409	Peptidoglycan-binding domain 1 protein
L7754_RS07640	COG5632	N-Acetylmuramoyl-L-alanine amidase
L7754_RS07875	COG2849	repeat protein
L7754_RS07880	COG5444	nuclease activity
L7754_RS07905	COG1876	peptidase activity
L7754_RS07910	COG2843	Capsule synthesis protein
L7754_RS07920	COG0477	Major facilitator Superfamily
L7754_RS07935	COG1846	Transcriptional regulator
L7754_RS07940	COG2814	Major facilitator Superfamily
L7754_RS07950	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L7754_RS07955	COG1131	(ABC) transporter
L7754_RS07975	COG2031	fatty acid transporter
L7754_RS07985	COG2249	NAD(P)H dehydrogenase (quinone) activity
L7754_RS08040	COG1288	antiporter activity
L7754_RS08045	COG2356	endonuclease I
L7754_RS08065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L7754_RS08085	COG1733	regulation of RNA biosynthetic process
L7754_RS08090	COG0778	Nitroreductase
L7754_RS08120	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS08130	COG1131	(ABC) transporter
L7754_RS08155	COG1011	Hydrolase
L7754_RS08165	COG2365	Tyrosine phosphatase family
L7754_RS08200	COG0628	permease
L7754_RS08255	COG1253	flavin adenine dinucleotide binding
L7754_RS08260	COG0789	Transcriptional regulator
L7754_RS08265	COG0697	spore germination
L7754_RS08275	COG1357	PFAM Pentapeptide repeats (8 copies)
L7754_RS08280	COG3813	Protein conserved in bacteria
L7754_RS08285	COG2706	6-phosphogluconolactonase activity
L7754_RS08290	COG1070	Carbohydrate kinase
L7754_RS08305	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
L7754_RS08310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L7754_RS08315	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L7754_RS08325	COG0604	alcohol dehydrogenase
L7754_RS08330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L7754_RS08335	COG3321	synthase
L7754_RS08335	COG0604	alcohol dehydrogenase
L7754_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS08355	COG0840	transmembrane signaling receptor activity
L7754_RS08365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L7754_RS08365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L7754_RS08370	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L7754_RS08370	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L7754_RS08375	COG1733	regulation of RNA biosynthetic process
L7754_RS08390	COG0656	L-ascorbic acid biosynthetic process
L7754_RS08395	COG2814	Major facilitator Superfamily
L7754_RS08420	COG0814	amino acid
L7754_RS08450	COG1733	regulation of RNA biosynthetic process
L7754_RS08455	COG2188	Transcriptional regulator
L7754_RS08460	COG0673	inositol 2-dehydrogenase activity
L7754_RS08465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
L7754_RS08470	COG1733	regulation of RNA biosynthetic process
L7754_RS08475	COG1733	regulation of RNA biosynthetic process
L7754_RS08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS08515	COG0384	phenazine biosynthesis protein PhzF
L7754_RS08525	COG0318	PFAM AMP-dependent synthetase and ligase
L7754_RS08530	COG2249	NAD(P)H dehydrogenase (quinone) activity
L7754_RS08535	COG1733	regulation of RNA biosynthetic process
L7754_RS08550	COG0726	polysaccharide deacetylase
L7754_RS08560	COG1191	sigma factor activity
L7754_RS08640	COG1151	hydroxylamine reductase activity
L7754_RS08665	COG2072	flavoprotein involved in K transport
L7754_RS08700	COG1113	amino acid transport
L7754_RS08705	COG2814	Major facilitator Superfamily
L7754_RS08730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
L7754_RS08735	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L7754_RS08750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS08755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS08760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS08765	COG3739	integral membrane protein
L7754_RS08795	COG0583	DNA-binding transcription factor activity
L7754_RS08815	COG1193	negative regulation of DNA recombination
L7754_RS08830	COG2162	N-hydroxyarylamine O-acetyltransferase activity
L7754_RS08835	COG1164	Oligoendopeptidase f
L7754_RS08860	COG3781	membrane
L7754_RS08875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L7754_RS08900	COG0584	glycerophosphoryl diester phosphodiesterase
L7754_RS08910	COG0640	Transcriptional regulator
L7754_RS08915	COG0604	alcohol dehydrogenase
L7754_RS08925	COG0457	Tetratricopeptide repeat
L7754_RS08935	COG2808	Putative FMN-binding domain
L7754_RS08940	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L7754_RS08955	COG0277	FAD linked oxidase domain protein
L7754_RS08995	COG1285	pathogenesis
L7754_RS09005	COG2514	catechol 2,3-dioxygenase activity
L7754_RS09010	COG2720	vancomycin resistance protein
L7754_RS09045	COG0716	FMN binding
L7754_RS09055	COG0494	nUDIX hydrolase
L7754_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS09085	COG0165	Argininosuccinate lyase
L7754_RS09100	COG4145	pantothenate transmembrane transporter activity
L7754_RS09110	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS09125	COG1657	PFAM Prenyltransferase squalene oxidase
L7754_RS09130	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
L7754_RS09135	COG2962	Rard protein
L7754_RS09140	COG3326	Membrane
L7754_RS09155	COG0489	protein tyrosine kinase activity
L7754_RS09165	COG0314	molybdopterin synthase activity
L7754_RS09170	COG0303	'Molybdopterin
L7754_RS09175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L7754_RS09180	COG2116	formate transmembrane transporter activity
L7754_RS09190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L7754_RS09195	COG5609	conserved protein (DUF2294)
L7754_RS09200	COG2427	Protein of unknown function (DUF1641)
L7754_RS09205	COG3383	formate dehydrogenase (NAD+) activity
L7754_RS09210	COG0697	spore germination
L7754_RS09225	COG0531	amino acid
L7754_RS09260	COG2226	methyltransferase
L7754_RS09265	COG4166	transmembrane transport
L7754_RS09270	COG4166	transmembrane transport
L7754_RS09275	COG4166	transmembrane transport
L7754_RS09280	COG1301	dicarboxylic acid transport
L7754_RS09285	COG1316	TRANSCRIPTIONal
L7754_RS09295	COG1595	DNA-templated transcription, initiation
L7754_RS09305	COG1131	(ABC) transporter
L7754_RS09340	COG0673	inositol 2-dehydrogenase activity
L7754_RS09345	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L7754_RS09350	COG0187	DNA topoisomerase II activity
L7754_RS09355	COG1832	CoA-binding protein
L7754_RS09360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L7754_RS09365	COG0745	RESPONSE REGULATOR receiver
L7754_RS09385	COG4841	protein insertion into membrane
L7754_RS09390	COG0824	Thioesterase
L7754_RS09415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L7754_RS09430	COG1132	(ABC) transporter
L7754_RS09435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L7754_RS09465	COG2211	Major facilitator Superfamily
L7754_RS09475	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
L7754_RS09490	COG0183	Belongs to the thiolase family
L7754_RS09495	COG0318	PFAM AMP-dependent synthetase and ligase
L7754_RS09500	COG1268	BioY protein
L7754_RS09505	COG0318	PFAM AMP-dependent synthetase and ligase
L7754_RS09510	COG1396	sequence-specific DNA binding
L7754_RS09545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS09555	COG5002	protein histidine kinase activity
L7754_RS09560	COG0400	carboxylic ester hydrolase activity
L7754_RS09565	COG0346	lactoylglutathione lyase activity
L7754_RS09570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L7754_RS09580	COG0069	glutamate synthase activity
L7754_RS09585	COG1902	pentaerythritol trinitrate reductase activity
L7754_RS09590	COG1329	Transcriptional regulator
L7754_RS09595	COG0010	Belongs to the arginase family
L7754_RS09645	COG4846	Membrane protein involved in cytochrome C biogenesis
L7754_RS09650	COG0785	Cytochrome C biogenesis protein
L7754_RS09660	COG1473	amidohydrolase
L7754_RS09670	COG1131	(ABC) transporter
L7754_RS09685	COG0583	DNA-binding transcription factor activity
L7754_RS09695	COG1346	cytolysis
L7754_RS09710	COG0730	response to heat
L7754_RS09735	COG1132	(ABC) transporter
L7754_RS09740	COG1132	(ABC) transporter
L7754_RS09765	COG3639	organic phosphonate transmembrane transporter activity
L7754_RS09775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L7754_RS09780	COG0737	Belongs to the 5'-nucleotidase family
L7754_RS09790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L7754_RS09810	COG1695	Transcriptional regulator
L7754_RS09820	COG5632	N-Acetylmuramoyl-L-alanine amidase
L7754_RS09820	COG3409	Peptidoglycan-binding domain 1 protein
L7754_RS09820	COG1388	LysM domain
L7754_RS09825	COG0739	heme binding
L7754_RS09830	COG0741	lytic transglycosylase activity
L7754_RS09860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L7754_RS09865	COG0174	glutamine synthetase
L7754_RS09870	COG0789	Transcriptional regulator
L7754_RS09875	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
L7754_RS09880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L7754_RS09885	COG2860	membrane
L7754_RS09895	COG0464	growth
L7754_RS09925	COG1388	LysM domain
L7754_RS09925	COG3584	3D domain protein
L7754_RS09930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L7754_RS09930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L7754_RS09930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L7754_RS09935	COG1105	Belongs to the carbohydrate kinase PfkB family
L7754_RS09940	COG1349	DNA-binding transcription factor activity
L7754_RS09945	COG1979	alcohol dehydrogenase
L7754_RS09950	COG2322	membrane
L7754_RS09960	COG1113	amino acid transport
L7754_RS09970	COG1408	metallophosphoesterase
L7754_RS09975	COG2116	formate transmembrane transporter activity
L7754_RS09990	COG2217	Heavy metal translocating P-type atpase
L7754_RS09995	COG2608	mercury ion transmembrane transporter activity
L7754_RS10000	COG1937	Protein conserved in bacteria
L7754_RS10010	COG2819	hydrolase of the alpha beta superfamily
L7754_RS10015	COG1120	ATPase activity
L7754_RS10020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS10025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS10030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS10035	COG0708	Exodeoxyribonuclease III
L7754_RS10040	COG2169	Transcriptional regulator
L7754_RS10045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L7754_RS10050	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L7754_RS10070	COG2267	carboxylic ester hydrolase activity
L7754_RS10075	COG5001	Diguanylate cyclase
L7754_RS10075	COG3300	MHYT domain
L7754_RS10095	COG1086	Polysaccharide biosynthesis protein
L7754_RS10115	COG1346	cytolysis
L7754_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS10135	COG2188	Transcriptional regulator
L7754_RS10140	COG2723	6-phospho-beta-galactosidase activity
L7754_RS10150	COG1404	Belongs to the peptidase S8 family
L7754_RS10155	COG3773	Cell wall hydrolase
L7754_RS10165	COG1368	sulfuric ester hydrolase activity
L7754_RS10170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L7754_RS10195	COG4550	Control of competence regulator ComK, YlbF/YmcA
L7754_RS10205	COG1013	pyruvate-flavodoxin oxidoreductase activity
L7754_RS10210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
L7754_RS10210	COG0674	pyruvate-flavodoxin oxidoreductase activity
L7754_RS10220	COG2359	stage V sporulation protein S
L7754_RS10225	COG1692	metallophosphoesterase
L7754_RS10245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L7754_RS10250	COG1426	Protein conserved in bacteria
L7754_RS10265	COG0300	oxidoreductase activity
L7754_RS10270	COG0612	Peptidase, M16
L7754_RS10275	COG0612	Peptidase, M16
L7754_RS10280	COG1079	Belongs to the binding-protein-dependent transport system permease family
L7754_RS10285	COG4603	Belongs to the binding-protein-dependent transport system permease family
L7754_RS10290	COG3845	ABC transporter
L7754_RS10295	COG1744	ABC transporter substrate-binding protein PnrA-like
L7754_RS10300	COG2188	Transcriptional regulator
L7754_RS10315	COG0740	serine-type endopeptidase activity
L7754_RS10320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L7754_RS10330	COG0527	aspartate kinase activity
L7754_RS10335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L7754_RS10340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L7754_RS10345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L7754_RS10350	COG1873	PFAM PRC-barrel domain
L7754_RS10355	COG0612	Peptidase, M16
L7754_RS10360	COG0726	polysaccharide deacetylase
L7754_RS10375	COG0196	riboflavin kinase activity
L7754_RS10385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
L7754_RS10390	COG1550	Protein conserved in bacteria
L7754_RS10400	COG1358	cellular component organization or biogenesis
L7754_RS10405	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L7754_RS10410	COG0195	Participates in both transcription termination and antitermination
L7754_RS10430	COG0750	zinc metalloprotease
L7754_RS10440	COG4589	Belongs to the CDS family
L7754_RS10485	COG4974	Belongs to the 'phage' integrase family
L7754_RS10495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L7754_RS10500	COG0758	DNA mediated transformation
L7754_RS10505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
L7754_RS10545	COG1837	Belongs to the UPF0109 family
L7754_RS10555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L7754_RS10565	COG0552	protein localization to endoplasmic reticulum
L7754_RS10570	COG1196	nuclear chromosome segregation
L7754_RS10580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L7754_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS10590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L7754_RS10605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L7754_RS10610	COG1461	Dihydroxyacetone kinase
L7754_RS10615	COG1302	Protein conserved in bacteria
L7754_RS10630	COG1564	THIamine pyrophosphokinase
L7754_RS10635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L7754_RS10645	COG2815	serine threonine protein kinase
L7754_RS10645	COG0515	serine threonine protein kinase
L7754_RS10650	COG0631	protein serine/threonine phosphatase activity
L7754_RS10660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L7754_RS10660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L7754_RS10675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L7754_RS10680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L7754_RS10700	COG1561	YicC-like family, N-terminal region
L7754_RS10705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L7754_RS10715	COG0006	proline dipeptidase activity
L7754_RS10725	COG3069	C4-dicarboxylate transmembrane transporter activity
L7754_RS10790	COG0564	pseudouridine synthase activity
L7754_RS10810	COG3599	regulation of cell shape
L7754_RS10815	COG2302	S4 RNA-binding domain
L7754_RS10820	COG0762	integral membrane protein
L7754_RS10825	COG1799	cell septum assembly
L7754_RS10830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L7754_RS10840	COG1873	PFAM PRC-barrel domain
L7754_RS10845	COG1191	sigma factor activity
L7754_RS10850	COG1191	sigma factor activity
L7754_RS10860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L7754_RS10865	COG0849	cell division
L7754_RS10885	COG0772	Belongs to the SEDS family
L7754_RS10905	COG0768	penicillin binding
L7754_RS10910	COG0768	penicillin binding
L7754_RS10930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
L7754_RS10945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
L7754_RS10950	COG1399	metal-binding, possibly nucleic acid-binding protein
L7754_RS10960	COG3480	Lon protease (S16) C-terminal proteolytic domain
L7754_RS10965	COG1752	Esterase of the alpha-beta hydrolase superfamily
L7754_RS10970	COG3314	Sporulation integral membrane protein YlbJ
L7754_RS10980	COG0742	ribosomal rna small subunit methyltransferase
L7754_RS10995	COG3679	Belongs to the UPF0342 family
L7754_RS11000	COG0406	alpha-ribazole phosphatase activity
L7754_RS11015	COG2340	Cysteine-rich secretory protein family
L7754_RS11030	COG3344	reverse transcriptase
L7754_RS11040	COG3336	cytochrome c oxidase
L7754_RS11075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
L7754_RS11080	COG0772	Belongs to the SEDS family
L7754_RS11090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
L7754_RS11095	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
L7754_RS11105	COG4896	Protein conserved in bacteria
L7754_RS11120	COG1217	gtp-binding protein TYPA
L7754_RS11130	COG0483	inositol monophosphate 1-phosphatase activity
L7754_RS11150	COG1982	Orn Lys Arg decarboxylase major
L7754_RS11200	COG0022	dehydrogenase e1 component
L7754_RS11205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L7754_RS11220	COG0561	phosphatase activity
L7754_RS11230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L7754_RS11235	COG0569	domain protein
L7754_RS11255	COG0583	DNA-binding transcription factor activity
L7754_RS11260	COG0517	IMP dehydrogenase activity
L7754_RS11270	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
L7754_RS11280	COG4703	Protein of unknown function (DUF1797)
L7754_RS11295	COG2200	EAL domain
L7754_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS11305	COG1408	metallophosphoesterase
L7754_RS11350	COG2814	Major facilitator Superfamily
L7754_RS11370	COG3209	COG3209 Rhs family protein
L7754_RS11380	COG2205	protein histidine kinase activity
L7754_RS11390	COG0436	Aminotransferase
L7754_RS11395	COG1609	Transcriptional regulator
L7754_RS11400	COG3833	ABC-type maltose transport systems, permease component
L7754_RS11405	COG1175	transmembrane transport
L7754_RS11410	COG2182	Extracellular solute-binding protein
L7754_RS11420	COG0366	Alpha amylase catalytic
L7754_RS11425	COG3842	ATPase activity
L7754_RS11465	COG0183	Belongs to the thiolase family
L7754_RS11500	COG1695	Transcriptional regulator
L7754_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS11525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L7754_RS11530	COG0436	Aminotransferase
L7754_RS11565	COG2084	Dehydrogenase
L7754_RS11575	COG2199	diguanylate cyclase activity
L7754_RS11580	COG0778	Nitroreductase
L7754_RS11605	COG1263	PTS System
L7754_RS11605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L7754_RS11605	COG2190	(PTS) system
L7754_RS11610	COG3711	transcriptional antiterminator
L7754_RS11620	COG2188	Transcriptional regulator
L7754_RS11635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
L7754_RS11660	COG1547	Domain of unknown function (DUF309)
L7754_RS11665	COG0456	acetyltransferase
L7754_RS11670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L7754_RS11675	COG4086	secreted protein
L7754_RS11680	COG0561	phosphatase activity
L7754_RS11685	COG0697	spore germination
L7754_RS11700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L7754_RS11725	COG0733	neurotransmitter:sodium symporter activity
L7754_RS11745	COG1686	Belongs to the peptidase S11 family
L7754_RS11750	COG1725	Transcriptional regulator
L7754_RS11755	COG1131	(ABC) transporter
L7754_RS11775	COG1846	Transcriptional regulator
L7754_RS11790	COG0598	Magnesium transport protein CorA
L7754_RS11815	COG4974	Belongs to the 'phage' integrase family
L7754_RS11825	COG0735	belongs to the Fur family
L7754_RS11830	COG1300	Membrane
L7754_RS11850	COG0667	Aldo Keto reductase
L7754_RS11855	COG0656	L-ascorbic acid biosynthetic process
L7754_RS11860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L7754_RS11860	COG0456	acetyltransferase
L7754_RS11870	COG1525	nuclease
L7754_RS11870	COG0737	Belongs to the 5'-nucleotidase family
L7754_RS11870	COG4085	toxin activity
L7754_RS11880	COG0596	Alpha beta hydrolase
L7754_RS11885	COG2056	Na+-H+ antiporter family
L7754_RS11890	COG1609	Transcriptional regulator
L7754_RS11895	COG0456	acetyltransferase
L7754_RS11900	COG1073	alpha beta
L7754_RS11915	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L7754_RS11915	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L7754_RS11920	COG0307	riboflavin synthase, alpha
L7754_RS11950	COG1073	alpha beta
L7754_RS11950	COG2226	methyltransferase
L7754_RS11965	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L7754_RS11975	COG1757	Na H antiporter
L7754_RS11980	COG0737	Belongs to the 5'-nucleotidase family
L7754_RS11990	COG1522	sequence-specific DNA binding
L7754_RS12035	COG0300	oxidoreductase activity
L7754_RS12040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS12045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L7754_RS12050	COG1760	l-serine dehydratase
L7754_RS12055	COG1760	l-serine dehydratase
L7754_RS12085	COG1285	pathogenesis
L7754_RS12095	COG2195	Cleaves the N-terminal amino acid of tripeptides
L7754_RS12100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS12115	COG1376	ErfK ybiS ycfS ynhG family protein
L7754_RS12120	COG4129	membrane
L7754_RS12125	COG1126	abc transporter atp-binding protein
L7754_RS12130	COG0765	amino acid transport
L7754_RS12135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L7754_RS12155	COG2323	membrane
L7754_RS12160	COG0772	Belongs to the SEDS family
L7754_RS12165	COG0508	dehydrogenase complex catalyzes the overall conversion of
L7754_RS12170	COG0022	dehydrogenase e1 component
L7754_RS12175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L7754_RS12180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L7754_RS12195	COG0280	phosphate acetyltransferase
L7754_RS12200	COG3829	transcription factor binding
L7754_RS12200	COG3290	protein histidine kinase activity
L7754_RS12210	COG0584	glycerophosphoryl diester phosphodiesterase
L7754_RS12215	COG3093	addiction module antidote protein HigA
L7754_RS12230	COG0750	zinc metalloprotease
L7754_RS12235	COG0497	DNA recombination
L7754_RS12245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L7754_RS12255	COG0142	geranyltranstransferase activity
L7754_RS12280	COG1302	Protein conserved in bacteria
L7754_RS12285	COG0439	Biotin carboxylase
L7754_RS12290	COG0511	ligase activity, forming carbon-carbon bonds
L7754_RS12335	COG3854	ATPases associated with a variety of cellular activities
L7754_RS12360	COG0006	proline dipeptidase activity
L7754_RS12375	COG3872	metal-dependent enzyme
L7754_RS12385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L7754_RS12420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L7754_RS12430	COG1609	Transcriptional regulator
L7754_RS12440	COG2076	Multidrug Resistance protein
L7754_RS12445	COG2076	Multidrug Resistance protein
L7754_RS12480	COG1131	(ABC) transporter
L7754_RS12485	COG1725	Transcriptional regulator
L7754_RS12515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L7754_RS12555	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L7754_RS12585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L7754_RS12590	COG2169	Transcriptional regulator
L7754_RS12615	COG2264	protein methyltransferase activity
L7754_RS12665	COG1459	type II secretion system
L7754_RS12670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L7754_RS12725	COG1410	methionine synthase
L7754_RS12725	COG0646	methionine synthase
L7754_RS12730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L7754_RS12730	COG0646	methionine synthase
L7754_RS12735	COG0626	cystathionine gamma-synthase activity
L7754_RS12740	COG0626	cystathionine gamma-synthase activity
L7754_RS12760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS12770	COG1940	carbohydrate kinase activity
L7754_RS12775	COG4483	Protein conserved in bacteria
L7754_RS12780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L7754_RS12785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L7754_RS12790	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L7754_RS12795	COG0704	Plays a role in the regulation of phosphate uptake
L7754_RS12805	COG0573	inorganic phosphate transmembrane transporter activity
L7754_RS12810	COG0573	inorganic phosphate transmembrane transporter activity
L7754_RS12815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L7754_RS12820	COG0768	penicillin binding
L7754_RS12825	COG0477	Major facilitator Superfamily
L7754_RS12830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L7754_RS12840	COG5521	maltodextrose utilization protein MalA
L7754_RS12855	COG0735	belongs to the Fur family
L7754_RS12860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L7754_RS12865	COG1121	(ABC) transporter
L7754_RS12870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS12900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L7754_RS12905	COG2384	SAM-dependent methyltransferase
L7754_RS12915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L7754_RS12920	COG0358	DNA primase activity
L7754_RS12935	COG0517	IMP dehydrogenase activity
L7754_RS12950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L7754_RS12955	COG0295	cytidine deaminase activity
L7754_RS12960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L7754_RS12970	COG1480	7TM receptor with intracellular HD hydrolase
L7754_RS12975	COG1702	phosphate starvation-inducible protein PhoH
L7754_RS12990	COG1610	YqeY-like protein
L7754_RS12995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
L7754_RS13000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
L7754_RS13005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L7754_RS13035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L7754_RS13040	COG1733	regulation of RNA biosynthetic process
L7754_RS13065	COG1466	dna polymerase III delta subunit
L7754_RS13075	COG0658	competence protein
L7754_RS13075	COG2333	competence protein COMEC
L7754_RS13080	COG2131	deaminase
L7754_RS13085	COG1555	photosystem II stabilization
L7754_RS13085	COG1596	polysaccharide export
L7754_RS13090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L7754_RS13095	COG2226	methyltransferase
L7754_RS13100	COG0799	negative regulation of ribosome biogenesis
L7754_RS13105	COG1713	HD superfamily hydrolase involved in NAD metabolism
L7754_RS13115	COG1534	Rna-binding protein
L7754_RS13125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L7754_RS13130	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
L7754_RS13165	COG0778	Nitroreductase
L7754_RS13170	COG2357	RelA SpoT domain protein
L7754_RS13180	COG1785	Belongs to the alkaline phosphatase family
L7754_RS13190	COG2267	carboxylic ester hydrolase activity
L7754_RS13225	COG1404	Belongs to the peptidase S8 family
L7754_RS13230	COG3186	Phenylalanine-4-hydroxylase
L7754_RS13240	COG2514	catechol 2,3-dioxygenase activity
L7754_RS13245	COG2259	Doxx family
L7754_RS13285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS13295	COG1454	alcohol dehydrogenase
L7754_RS13295	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS13300	COG0626	cystathionine gamma-synthase activity
L7754_RS13305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L7754_RS13330	COG0768	penicillin binding
L7754_RS13350	COG0826	peptidase U32
L7754_RS13355	COG0826	peptidase U32
L7754_RS13360	COG4122	O-methyltransferase activity
L7754_RS13365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L7754_RS13395	COG0628	permease
L7754_RS13415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L7754_RS13430	COG1104	cysteine desulfurase activity
L7754_RS13435	COG1959	2 iron, 2 sulfur cluster binding
L7754_RS13440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L7754_RS13450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L7754_RS13475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L7754_RS13485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L7754_RS13485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L7754_RS13490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L7754_RS13495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L7754_RS13495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L7754_RS13505	COG2244	polysaccharide biosynthetic process
L7754_RS13510	COG2323	membrane
L7754_RS13520	COG1862	Preprotein translocase
L7754_RS13550	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
L7754_RS13580	COG0157	Belongs to the NadC ModD family
L7754_RS13585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
L7754_RS13590	COG1104	cysteine desulfurase activity
L7754_RS13595	COG1827	regulation of RNA biosynthetic process
L7754_RS13600	COG2258	MOSC domain
L7754_RS13605	COG0077	Prephenate dehydratase
L7754_RS13610	COG0577	efflux transmembrane transporter activity
L7754_RS13615	COG0577	efflux transmembrane transporter activity
L7754_RS13620	COG1136	(ABC) transporter
L7754_RS13625	COG5002	protein histidine kinase activity
L7754_RS13630	COG0745	RESPONSE REGULATOR receiver
L7754_RS13640	COG3290	protein histidine kinase activity
L7754_RS13650	COG2868	ribosomal protein
L7754_RS13660	COG1530	ribonuclease E activity
L7754_RS13665	COG1994	Peptidase M50
L7754_RS13670	COG0739	heme binding
L7754_RS13675	COG2894	cell division
L7754_RS13695	COG1077	Cell shape determining protein MreB Mrl
L7754_RS13715	COG0285	dihydrofolate synthase activity
L7754_RS13730	COG1388	LysM domain
L7754_RS13740	COG0113	porphobilinogen synthase activity
L7754_RS13745	COG1587	Uroporphyrinogen-III synthase
L7754_RS13755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L7754_RS13765	COG1846	Transcriptional regulator
L7754_RS13770	COG1764	response to oxidative stress
L7754_RS13785	COG0470	DNA polymerase III
L7754_RS13785	COG1067	ATP-dependent peptidase activity
L7754_RS13830	COG0622	Phosphoesterase
L7754_RS13845	COG5401	PFAM Sporulation and spore germination
L7754_RS13865	COG1309	transcriptional regulator
L7754_RS13885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L7754_RS13915	COG1999	signal sequence binding
L7754_RS13920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L7754_RS13925	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
L7754_RS13990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L7754_RS14015	COG2197	response regulator
L7754_RS14020	COG2233	PERMEase
L7754_RS14025	COG0402	S-adenosylhomocysteine deaminase activity
L7754_RS14030	COG1983	PspC domain protein
L7754_RS14035	COG1396	sequence-specific DNA binding
L7754_RS14040	COG0697	spore germination
L7754_RS14050	COG1959	2 iron, 2 sulfur cluster binding
L7754_RS14055	COG1668	transmembrane transport
L7754_RS14060	COG4152	abc transporter atp-binding protein
L7754_RS14065	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
L7754_RS14070	COG1360	Flagellar Motor Protein
L7754_RS14075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
L7754_RS14080	COG1876	peptidase activity
L7754_RS14085	COG0824	Thioesterase
L7754_RS14090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L7754_RS14095	COG1053	succinate dehydrogenase
L7754_RS14100	COG2009	succinate dehydrogenase
L7754_RS14105	COG1719	4-vinyl reductase, 4VR
L7754_RS14115	COG3118	belongs to the thioredoxin family
L7754_RS14120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
L7754_RS14125	COG2086	electron transfer activity
L7754_RS14130	COG1024	Enoyl-CoA hydratase
L7754_RS14135	COG1309	transcriptional regulator
L7754_RS14140	COG0318	PFAM AMP-dependent synthetase and ligase
L7754_RS14165	COG2318	DinB family
L7754_RS14190	COG1131	(ABC) transporter
L7754_RS14195	COG2205	protein histidine kinase activity
L7754_RS14200	COG0745	RESPONSE REGULATOR receiver
L7754_RS14210	COG4895	conserved protein (DUF2196)
L7754_RS14215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L7754_RS14225	COG4509	Sortase family
L7754_RS14230	COG1120	ATPase activity
L7754_RS14245	COG5386	Cell surface protein
L7754_RS14255	COG5386	Cell surface protein
L7754_RS14260	COG1114	Component of the transport system for branched-chain amino acids
L7754_RS14265	COG1187	pseudouridine synthase activity
L7754_RS14275	COG1796	DNA polymerase
L7754_RS14275	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L7754_RS14280	COG1286	toxin biosynthetic process
L7754_RS14320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L7754_RS14330	COG1418	mRNA catabolic process
L7754_RS14345	COG2814	Major facilitator Superfamily
L7754_RS14350	COG1566	PFAM secretion protein HlyD family protein
L7754_RS14355	COG1309	transcriptional regulator
L7754_RS14360	COG1363	Peptidase, m42
L7754_RS14385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
L7754_RS14400	COG1484	DNA-dependent DNA replication
L7754_RS14405	COG3611	Membrane attachment protein
L7754_RS14415	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
L7754_RS14420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L7754_RS14430	COG1971	Probably functions as a manganese efflux pump
L7754_RS14440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L7754_RS14440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L7754_RS14445	COG5002	protein histidine kinase activity
L7754_RS14450	COG0745	RESPONSE REGULATOR receiver
L7754_RS14470	COG0538	isocitrate dehydrogenase activity
L7754_RS14475	COG0372	Belongs to the citrate synthase family
L7754_RS14485	COG0628	permease
L7754_RS14490	COG3030	protein affecting phage T7 exclusion by the F plasmid
L7754_RS14515	COG1725	Transcriptional regulator
L7754_RS14520	COG0281	malic enzyme
L7754_RS14525	COG0587	DNA-directed DNA polymerase activity
L7754_RS14540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L7754_RS14555	COG4109	DRTGG domain
L7754_RS14570	COG0006	proline dipeptidase activity
L7754_RS14605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS14610	COG0662	Cupin 2, conserved barrel domain protein
L7754_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS14630	COG0589	response to stress
L7754_RS14670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS14695	COG0827	DNA restriction-modification system
L7754_RS14700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L7754_RS14710	COG3874	Sporulation protein YtfJ
L7754_RS14725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
L7754_RS14735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L7754_RS14750	COG1104	cysteine desulfurase activity
L7754_RS14760	COG0583	DNA-binding transcription factor activity
L7754_RS14765	COG0697	spore germination
L7754_RS14770	COG1309	transcriptional regulator
L7754_RS14775	COG1956	GAF domain-containing protein
L7754_RS14780	COG0626	cystathionine gamma-synthase activity
L7754_RS14815	COG0110	maltose O-acetyltransferase activity
L7754_RS14820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L7754_RS14825	COG0454	-acetyltransferase
L7754_RS14830	COG0517	IMP dehydrogenase activity
L7754_RS14835	COG0123	including yeast histone deacetylase and acetoin utilization protein
L7754_RS14850	COG0745	RESPONSE REGULATOR receiver
L7754_RS14860	COG0666	response to abiotic stimulus
L7754_RS14895	COG1609	Transcriptional regulator
L7754_RS14900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
L7754_RS14900	COG1605	Chorismate mutase
L7754_RS14905	COG4851	CamS sex pheromone cAM373 precursor
L7754_RS14910	COG3118	belongs to the thioredoxin family
L7754_RS14920	COG2309	aminopeptidase activity
L7754_RS14945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS14960	COG1674	ftsk spoiiie
L7754_RS14965	COG1388	LysM domain
L7754_RS14965	COG0860	N-Acetylmuramoyl-L-alanine amidase
L7754_RS14975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L7754_RS14985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L7754_RS14990	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
L7754_RS14995	COG1363	Peptidase, m42
L7754_RS15005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS15020	COG0510	thiamine kinase activity
L7754_RS15025	COG1523	belongs to the glycosyl hydrolase 13 family
L7754_RS15035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L7754_RS15040	COG1349	DNA-binding transcription factor activity
L7754_RS15045	COG1187	pseudouridine synthase activity
L7754_RS15050	COG2244	polysaccharide biosynthetic process
L7754_RS15055	COG2081	HI0933 family
L7754_RS15060	COG2814	Major facilitator Superfamily
L7754_RS15070	COG3832	glyoxalase III activity
L7754_RS15090	COG1329	Transcriptional regulator
L7754_RS15115	COG0314	molybdopterin synthase activity
L7754_RS15120	COG1763	Mo-molybdopterin cofactor biosynthetic process
L7754_RS15125	COG0303	'Molybdopterin
L7754_RS15135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L7754_RS15140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L7754_RS15160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L7754_RS15170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L7754_RS15210	COG2814	Major facilitator Superfamily
L7754_RS15215	COG0475	glutathione-regulated potassium exporter activity
L7754_RS15220	COG0490	domain, Protein
L7754_RS15225	COG0582	viral genome integration into host DNA
L7754_RS15235	COG1136	(ABC) transporter
L7754_RS15255	COG1242	4 iron, 4 sulfur cluster binding
L7754_RS15260	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L7754_RS15275	COG1794	racemase activity, acting on amino acids and derivatives
L7754_RS15290	COG2267	carboxylic ester hydrolase activity
L7754_RS15295	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L7754_RS15300	COG0671	phosphoesterase, PA-phosphatase related
L7754_RS15305	COG0438	transferase activity, transferring glycosyl groups
L7754_RS15325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS15370	COG5002	protein histidine kinase activity
L7754_RS15375	COG3852	Histidine kinase
L7754_RS15380	COG0753	catalase activity
L7754_RS15390	COG2267	carboxylic ester hydrolase activity
L7754_RS15395	COG1368	sulfuric ester hydrolase activity
L7754_RS15420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L7754_RS15425	COG1116	anion transmembrane transporter activity
L7754_RS15430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L7754_RS15455	COG0494	nUDIX hydrolase
L7754_RS15485	COG1854	S-ribosylhomocysteine lyase activity
L7754_RS15495	COG0288	reversible hydration of carbon dioxide
L7754_RS15500	COG1271	oxidase subunit
L7754_RS15505	COG1294	oxidase, subunit
L7754_RS15520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS15540	COG1842	Phage shock protein A
L7754_RS15570	COG5002	protein histidine kinase activity
L7754_RS15575	COG0745	RESPONSE REGULATOR receiver
L7754_RS15600	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L7754_RS15605	COG1597	lipid kinase activity
L7754_RS15645	COG0577	efflux transmembrane transporter activity
L7754_RS15650	COG1136	(ABC) transporter
L7754_RS15665	COG0586	Pfam SNARE associated Golgi protein
L7754_RS15675	COG0577	efflux transmembrane transporter activity
L7754_RS15680	COG1136	(ABC) transporter
L7754_RS15685	COG3708	Transcriptional regulator
L7754_RS15685	COG2207	Transcriptional regulator
L7754_RS15690	COG5658	integral membrane protein
L7754_RS15695	COG0640	Transcriptional regulator
L7754_RS15700	COG0745	RESPONSE REGULATOR receiver
L7754_RS15705	COG2205	protein histidine kinase activity
L7754_RS15710	COG0577	efflux transmembrane transporter activity
L7754_RS15715	COG0577	efflux transmembrane transporter activity
L7754_RS15720	COG1136	(ABC) transporter
L7754_RS15725	COG0577	efflux transmembrane transporter activity
L7754_RS15750	COG2188	Transcriptional regulator
L7754_RS15770	COG3964	amidohydrolase
L7754_RS15790	COG4948	Mandelate Racemase Muconate Lactonizing
L7754_RS15800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
L7754_RS15805	COG0596	Alpha beta hydrolase
L7754_RS15815	COG1169	isochorismate synthase
L7754_RS15820	COG1575	Belongs to the MenA family. Type 1 subfamily
L7754_RS15825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L7754_RS15850	COG0058	SHG alpha-glucan phosphorylase activity
L7754_RS15860	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L7754_RS15880	COG1404	Belongs to the peptidase S8 family
L7754_RS15980	COG0544	peptidyl-prolyl cis-trans isomerase activity
L7754_RS16015	COG1285	pathogenesis
L7754_RS16020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L7754_RS16035	COG2155	Conserved Protein
L7754_RS16040	COG1098	S1 RNA binding domain
L7754_RS16045	COG0436	Aminotransferase
L7754_RS16050	COG1522	sequence-specific DNA binding
L7754_RS16055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
L7754_RS16060	COG2267	carboxylic ester hydrolase activity
L7754_RS16070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L7754_RS16090	COG5018	Exonuclease
L7754_RS16095	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L7754_RS16115	COG2050	protein possibly involved in aromatic compounds catabolism
L7754_RS16125	COG1268	BioY protein
L7754_RS16130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L7754_RS16135	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L7754_RS16155	COG2076	Multidrug Resistance protein
L7754_RS16160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L7754_RS16170	COG3584	3D domain protein
L7754_RS16185	COG1252	NADH dehydrogenase
L7754_RS16200	COG3708	Transcriptional regulator
L7754_RS16215	COG1683	Conserved Protein
L7754_RS16240	COG0316	Belongs to the HesB IscA family
L7754_RS16255	COG1252	NADH dehydrogenase
L7754_RS16270	COG0390	transport system, permease component
L7754_RS16275	COG2824	Alkylphosphonate utilization operon protein PhnA
L7754_RS16315	COG4837	Protein of unknown function (DUF1462)
L7754_RS16320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
L7754_RS16330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L7754_RS16335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L7754_RS16345	COG2249	NAD(P)H dehydrogenase (quinone) activity
L7754_RS16355	COG0647	UMP catabolic process
L7754_RS16365	COG2445	Protein of unknown function DUF86
L7754_RS16370	COG1494	fructose-1,6-bisphosphatase
L7754_RS16390	COG4470	Protein conserved in bacteria
L7754_RS16400	COG0789	Transcriptional regulator
L7754_RS16405	COG4377	Putative membrane peptidase family (DUF2324)
L7754_RS16430	COG0739	heme binding
L7754_RS16440	COG3377	Domain of unknown function (DUF1805)
L7754_RS16445	COG0737	Belongs to the 5'-nucleotidase family
L7754_RS16450	COG0719	Fe-S assembly protein
L7754_RS16455	COG0822	iron-sulfur transferase activity
L7754_RS16460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L7754_RS16465	COG0719	Fe-S assembly protein
L7754_RS16470	COG0396	ATPase activity
L7754_RS16475	COG1464	Belongs to the NlpA lipoprotein family
L7754_RS16480	COG1464	Belongs to the NlpA lipoprotein family
L7754_RS16485	COG2011	ABC-type metal ion transport system permease component
L7754_RS16500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L7754_RS16505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L7754_RS16515	COG1393	Belongs to the ArsC family
L7754_RS16555	COG1309	transcriptional regulator
L7754_RS16560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS16565	COG1960	acyl-CoA dehydrogenase activity
L7754_RS16570	COG0183	Belongs to the thiolase family
L7754_RS16575	COG1250	3-hydroxyacyl-CoA dehydrogenase
L7754_RS16575	COG1024	Enoyl-CoA hydratase
L7754_RS16585	COG1686	Belongs to the peptidase S11 family
L7754_RS16600	COG0011	TIGRFAM Protein of
L7754_RS16605	COG0840	transmembrane signaling receptor activity
L7754_RS16620	COG2814	Major facilitator Superfamily
L7754_RS16625	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
L7754_RS16635	COG0531	amino acid
L7754_RS16665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS16705	COG0586	Pfam SNARE associated Golgi protein
L7754_RS16715	COG1376	ErfK ybiS ycfS ynhG family protein
L7754_RS16720	COG0745	RESPONSE REGULATOR receiver
L7754_RS16725	COG5002	protein histidine kinase activity
L7754_RS16765	COG0840	transmembrane signaling receptor activity
L7754_RS16770	COG2151	metal-sulfur cluster biosynthetic enzyme
L7754_RS16775	COG3227	Zinc metalloprotease (Elastase)
L7754_RS16780	COG1741	Belongs to the pirin family
L7754_RS16795	COG0586	Pfam SNARE associated Golgi protein
L7754_RS16800	COG0475	glutathione-regulated potassium exporter activity
L7754_RS16805	COG0490	domain, Protein
L7754_RS16810	COG1115	amino acid carrier protein
L7754_RS16815	COG0783	Belongs to the Dps family
L7754_RS16830	COG1611	Belongs to the LOG family
L7754_RS16840	COG1528	Iron-storage protein
L7754_RS16850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS16855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS16860	COG1115	amino acid carrier protein
L7754_RS16865	COG1115	amino acid carrier protein
L7754_RS16870	COG2910	NAD(P)H-binding
L7754_RS16885	COG0656	L-ascorbic acid biosynthetic process
L7754_RS16890	COG2814	Major facilitator Superfamily
L7754_RS16895	COG1733	regulation of RNA biosynthetic process
L7754_RS16905	COG1252	NADH dehydrogenase
L7754_RS16910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L7754_RS16960	COG0488	(ABC) transporter
L7754_RS16965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS17040	COG0557	exoribonuclease II activity
L7754_RS17045	COG1647	Serine aminopeptidase, S33
L7754_RS17050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L7754_RS17055	COG1346	cytolysis
L7754_RS17090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L7754_RS17105	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
L7754_RS17115	COG1668	transmembrane transport
L7754_RS17120	COG4152	abc transporter atp-binding protein
L7754_RS17125	COG4585	Histidine kinase
L7754_RS17155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
L7754_RS17170	COG2323	membrane
L7754_RS17180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L7754_RS17190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L7754_RS17200	COG1051	belongs to the nudix hydrolase family
L7754_RS17210	COG0492	ferredoxin-NADP+ reductase activity
L7754_RS17215	COG0457	Tetratricopeptide repeat
L7754_RS17220	COG0110	maltose O-acetyltransferase activity
L7754_RS17240	COG1950	PFAM Membrane protein of
L7754_RS17245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L7754_RS17250	COG0556	nucleotide-excision repair
L7754_RS17265	COG0789	Transcriptional regulator
L7754_RS17285	COG0583	DNA-binding transcription factor activity
L7754_RS17295	COG0655	NAD(P)H dehydrogenase (quinone) activity
L7754_RS17300	COG0488	(ABC) transporter
L7754_RS17310	COG1132	(ABC) transporter
L7754_RS17315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L7754_RS17320	COG0793	Belongs to the peptidase S41A family
L7754_RS17320	COG3409	Peptidoglycan-binding domain 1 protein
L7754_RS17325	COG2177	Part of the ABC transporter FtsEX involved in
L7754_RS17330	COG2884	Cell division ATP-binding protein ftsE
L7754_RS17355	COG1131	(ABC) transporter
L7754_RS17385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
L7754_RS17390	COG1278	Cold shock
L7754_RS17395	COG1040	competence protein
L7754_RS17400	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L7754_RS17405	COG0791	NLP P60 protein
L7754_RS17410	COG1733	regulation of RNA biosynthetic process
L7754_RS17415	COG1307	EDD domain protein, DegV family
L7754_RS17420	COG1739	Uncharacterized protein family UPF0029
L7754_RS17425	COG1316	TRANSCRIPTIONal
L7754_RS17430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L7754_RS17435	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
L7754_RS17440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L7754_RS17450	COG3933	PFAM sigma-54 factor interaction domain-containing protein
L7754_RS17450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
L7754_RS17470	COG1486	melibiose metabolic process
L7754_RS17475	COG1447	Phosphotransferase system cellobiose-specific component IIA
L7754_RS17480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L7754_RS17500	COG1447	Phosphotransferase system cellobiose-specific component IIA
L7754_RS17510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L7754_RS17515	COG1301	dicarboxylic acid transport
L7754_RS17545	COG1511	domain protein
L7754_RS17550	COG0583	DNA-binding transcription factor activity
L7754_RS17555	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
L7754_RS17565	COG1271	oxidase subunit
L7754_RS17570	COG1294	oxidase, subunit
L7754_RS17575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
L7754_RS17585	COG1620	l-lactate permease
L7754_RS17595	COG2389	metal-binding protein
L7754_RS17605	COG1368	sulfuric ester hydrolase activity
L7754_RS17615	COG0791	NLP P60 protein
L7754_RS17615	COG1388	LysM domain
L7754_RS17620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS17630	COG1215	transferase activity, transferring glycosyl groups
L7754_RS17635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L7754_RS17640	COG1388	LysM domain
L7754_RS17640	COG3584	3D domain protein
L7754_RS17665	COG4715	Zinc finger, swim domain protein
L7754_RS17670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L7754_RS17710	COG0577	efflux transmembrane transporter activity
L7754_RS17715	COG1136	(ABC) transporter
L7754_RS17740	COG5002	protein histidine kinase activity
L7754_RS17745	COG0745	RESPONSE REGULATOR receiver
L7754_RS17750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L7754_RS17765	COG1091	dTDP-4-dehydrorhamnose reductase activity
L7754_RS17780	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L7754_RS17785	COG0438	transferase activity, transferring glycosyl groups
L7754_RS17795	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
L7754_RS17800	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
L7754_RS17815	COG1215	transferase activity, transferring glycosyl groups
L7754_RS17820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L7754_RS17825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L7754_RS17830	COG4464	protein tyrosine phosphatase activity
L7754_RS17835	COG0489	protein tyrosine kinase activity
L7754_RS17840	COG3944	biosynthesis protein
L7754_RS17845	COG0489	protein tyrosine kinase activity
L7754_RS17860	COG1609	Transcriptional regulator
L7754_RS17870	COG0739	heme binding
L7754_RS17885	COG4555	ABC transporter
L7754_RS17890	COG2385	sporulation resulting in formation of a cellular spore
L7754_RS17905	COG4836	Membrane
L7754_RS17910	COG1007	ATP synthesis coupled electron transport
L7754_RS17915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L7754_RS17920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L7754_RS17930	COG0839	Belongs to the complex I subunit 6 family
L7754_RS17950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L7754_RS17965	COG3300	MHYT domain
L7754_RS17965	COG5001	Diguanylate cyclase
L7754_RS18015	COG0356	it plays a direct role in the translocation of protons across the membrane
L7754_RS18050	COG0698	ribose 5-phosphate isomerase
L7754_RS18065	COG2259	Doxx family
L7754_RS18070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L7754_RS18085	COG0009	L-threonylcarbamoyladenylate synthase
L7754_RS18120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
L7754_RS18125	COG1494	fructose-1,6-bisphosphatase
L7754_RS18145	COG4821	SIS domain
L7754_RS18165	COG1960	acyl-CoA dehydrogenase activity
L7754_RS18170	COG1960	acyl-CoA dehydrogenase activity
L7754_RS18175	COG1250	3-hydroxyacyl-CoA dehydrogenase
L7754_RS18180	COG0183	Belongs to the thiolase family
L7754_RS18185	COG0247	lactate metabolic process
L7754_RS18185	COG2181	nitrate reductase activity
L7754_RS18190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L7754_RS18200	COG3300	MHYT domain
L7754_RS18200	COG5001	Diguanylate cyclase
L7754_RS18215	COG3227	Zinc metalloprotease (Elastase)
L7754_RS18220	COG2197	response regulator
L7754_RS18225	COG4585	Histidine kinase
L7754_RS18230	COG0842	Transport permease protein
L7754_RS18235	COG1131	(ABC) transporter
L7754_RS18240	COG0024	Methionine aminopeptidase
L7754_RS18250	COG2234	aminopeptidase activity
L7754_RS18270	COG1595	DNA-templated transcription, initiation
L7754_RS18280	COG4506	Protein conserved in bacteria
L7754_RS18285	COG1619	proteins homologs of microcin C7 resistance protein MccF
L7754_RS18310	COG2814	Major facilitator Superfamily
L7754_RS18315	COG0789	Transcriptional regulator
L7754_RS18320	COG0584	glycerophosphoryl diester phosphodiesterase
L7754_RS18325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L7754_RS18335	COG1994	Peptidase M50
L7754_RS18345	COG1078	dGTPase activity
L7754_RS18350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS18355	COG1120	ATPase activity
L7754_RS18360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS18385	COG0280	phosphate acetyltransferase
L7754_RS18400	COG3773	Cell wall hydrolase
L7754_RS18410	COG2363	Small membrane protein
L7754_RS18420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L7754_RS18425	COG2233	PERMEase
L7754_RS18430	COG0561	phosphatase activity
L7754_RS18435	COG2814	Major facilitator Superfamily
L7754_RS18445	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
L7754_RS18450	COG1131	(ABC) transporter
L7754_RS18455	COG2755	lipolytic protein G-D-S-L family
L7754_RS18460	COG1609	Transcriptional regulator
L7754_RS18470	COG0460	homoserine dehydrogenase
L7754_RS18480	COG2873	o-acetylhomoserine
L7754_RS18490	COG1011	Hydrolase
L7754_RS18495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L7754_RS18505	COG2197	response regulator
L7754_RS18510	COG2203	Gaf domain
L7754_RS18510	COG4585	Histidine kinase
L7754_RS18515	COG0351	phosphomethylpyrimidine kinase
L7754_RS18520	COG3706	GGDEF domain
L7754_RS18525	COG2879	small protein
L7754_RS18530	COG1966	Carbon starvation protein
L7754_RS18535	COG3279	Response regulator of the LytR AlgR family
L7754_RS18540	COG0477	Major facilitator Superfamily
L7754_RS18550	COG0438	transferase activity, transferring glycosyl groups
L7754_RS18565	COG0840	transmembrane signaling receptor activity
L7754_RS18575	COG1607	acyl-coa hydrolase
L7754_RS18580	COG1216	Glycosyl transferase, family 2
L7754_RS18590	COG1216	Glycosyl transferase, family 2
L7754_RS18600	COG4485	Bacterial membrane protein, YfhO
L7754_RS18605	COG0463	Glycosyl transferase, family 2
L7754_RS18610	COG0488	(ABC) transporter
L7754_RS18615	COG1309	transcriptional regulator
L7754_RS18620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L7754_RS18625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L7754_RS18625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L7754_RS18630	COG0628	permease
L7754_RS18650	COG3275	phosphorelay sensor kinase activity
L7754_RS18655	COG2814	Major facilitator Superfamily
L7754_RS18660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L7754_RS18665	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
L7754_RS18685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L7754_RS18690	COG1272	protein, Hemolysin III
L7754_RS18710	COG1164	Oligoendopeptidase f
L7754_RS18720	COG5002	protein histidine kinase activity
L7754_RS18735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L7754_RS18740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L7754_RS18745	COG4853	Protein conserved in bacteria
L7754_RS18755	COG5002	protein histidine kinase activity
L7754_RS18760	COG0745	RESPONSE REGULATOR receiver
L7754_RS18790	COG0305	Participates in initiation and elongation during chromosome replication
L7754_RS18800	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
L7754_RS18805	COG4241	membrane
L7754_RS18825	COG0012	GTP binding
L7754_RS18830	COG4481	Protein conserved in bacteria
L7754_RS18835	COG0668	transmembrane transport
L7754_RS18845	COG1475	DNA binding
L7754_RS18850	COG1192	Involved in chromosome partitioning
L7754_RS18875	COG1847	R3H domain protein
L7754_RS18890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
L7754_RS18900	COG0592	DNA-directed DNA polymerase activity
L7754_RS18905	COG2501	S4 domain
L7754_RS18915	COG0187	DNA topoisomerase II activity
L7754_RS18920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L7754_RS18955	COG0516	GMP reductase activity
L7754_RS18955	COG0517	IMP dehydrogenase activity
L7754_RS18960	COG1686	Belongs to the peptidase S11 family
L7754_RS18990	COG1428	Deoxynucleoside kinase
L7754_RS18995	COG1428	Deoxynucleoside kinase
L7754_RS19000	COG1335	isochorismatase
L7754_RS19005	COG0590	tRNA wobble adenosine to inosine editing
L7754_RS19015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L7754_RS19070	COG1982	Orn Lys Arg decarboxylase major
L7754_RS19080	COG0470	DNA polymerase III
L7754_RS19085	COG1774	PSP1 C-terminal conserved region
L7754_RS19095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L7754_RS19105	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
L7754_RS19110	COG2002	toxin-antitoxin pair type II binding
L7754_RS19120	COG0084	hydrolase, TatD family'
L7754_RS19140	COG4466	Protein conserved in bacteria
L7754_RS19155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L7754_RS19160	COG0251	oxidation-reduction process
L7754_RS19190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L7754_RS19195	COG2002	toxin-antitoxin pair type II binding
L7754_RS19200	COG2244	polysaccharide biosynthetic process
L7754_RS19205	COG3956	TIGRFAM MazG family protein
L7754_RS19210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L7754_RS19230	COG1098	S1 RNA binding domain
L7754_RS19245	COG2208	phosphoserine phosphatase activity
L7754_RS19255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L7754_RS19260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L7754_RS19275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L7754_RS19280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L7754_RS19285	COG0512	Glutamine amidotransferase of anthranilate synthase
L7754_RS19290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L7754_RS19295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L7754_RS19300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L7754_RS19305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L7754_RS19310	COG1396	sequence-specific DNA binding
L7754_RS19315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L7754_RS19405	COG3880	PFAM UvrB UvrC protein
L7754_RS19415	COG0542	response to heat
L7754_RS19420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L7754_RS19430	COG4956	integral membrane protein (PIN domain superfamily)
L7754_RS19450	COG1045	serine acetyltransferase
L7754_RS19465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L7754_RS19470	COG3688	RNA-binding protein containing a PIN domain
L7754_RS19485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
L7754_RS19490	COG0250	Participates in transcription elongation, termination and antitermination
L7754_RS19495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
L7754_RS19515	COG2813	Specifically methylates the guanine in position
L7754_RS19530	COG1358	cellular component organization or biogenesis
L7754_RS19535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
L7754_RS19600	COG0255	Belongs to the universal ribosomal protein uL29 family
L7754_RS19660	COG0201	protein transport
L7754_RS19670	COG0024	Methionine aminopeptidase
L7754_RS19680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L7754_RS19715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L7754_RS19740	COG0860	N-Acetylmuramoyl-L-alanine amidase
L7754_RS19745	COG0489	protein tyrosine kinase activity
L7754_RS19755	COG2194	sulfuric ester hydrolase activity
L7754_RS19760	COG0726	polysaccharide deacetylase
L7754_RS19840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L7754_RS19845	COG4856	YbbR-like protein
L7754_RS19935	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS19940	COG2011	ABC-type metal ion transport system permease component
L7754_RS19945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L7754_RS19950	COG1464	Belongs to the NlpA lipoprotein family
L7754_RS19955	COG0604	alcohol dehydrogenase
L7754_RS19965	COG0277	FAD linked oxidase domain protein
L7754_RS19970	COG2271	Major facilitator Superfamily
L7754_RS19980	COG2814	Major facilitator Superfamily
L7754_RS19995	COG0601	transmembrane transport
L7754_RS20000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L7754_RS20005	COG0444	Belongs to the ABC transporter superfamily
L7754_RS20010	COG4608	Belongs to the ABC transporter superfamily
L7754_RS20015	COG4166	transmembrane transport
L7754_RS20025	COG2207	Transcriptional regulator
L7754_RS20040	COG4166	transmembrane transport
L7754_RS20045	COG4166	transmembrane transport
L7754_RS20050	COG0656	L-ascorbic acid biosynthetic process
L7754_RS20070	COG4149	molybdate abc transporter
L7754_RS20075	COG0725	ABC transporter, periplasmic molybdate-binding protein
L7754_RS20080	COG1910	domain protein
L7754_RS20095	COG0697	spore germination
L7754_RS20110	COG0204	Acyl-transferase
L7754_RS20120	COG1609	Transcriptional regulator
L7754_RS20130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS20145	COG5298	Protein conserved in bacteria
L7754_RS20170	COG0488	(ABC) transporter
L7754_RS20180	COG0747	negative chemotaxis
L7754_RS20185	COG0601	transmembrane transport
L7754_RS20190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L7754_RS20195	COG0444	Belongs to the ABC transporter superfamily
L7754_RS20200	COG4608	Belongs to the ABC transporter superfamily
L7754_RS20205	COG0561	phosphatase activity
L7754_RS20235	COG3185	4-Hydroxyphenylpyruvate dioxygenase
L7754_RS20240	COG0179	Fumarylacetoacetate (FAA) hydrolase
L7754_RS20250	COG0531	amino acid
L7754_RS20255	COG2814	Major facilitator Superfamily
L7754_RS20265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L7754_RS20275	COG4294	response to UV
L7754_RS20280	COG0705	Rhomboid family
L7754_RS20290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L7754_RS20295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L7754_RS20300	COG0864	Transcriptional regulator
L7754_RS20305	COG2337	Toxic component of a toxin-antitoxin (TA) module
L7754_RS20310	COG2183	response to ionizing radiation
L7754_RS20410	COG0802	atpase or kinase
L7754_RS20415	COG1214	PFAM Peptidase M22, glycoprotease
L7754_RS20420	COG0456	acetyltransferase
L7754_RS20430	COG0488	(ABC) transporter
L7754_RS20445	COG1266	CAAX protease self-immunity
L7754_RS20465	COG2252	PERMEase
L7754_RS20475	COG5002	protein histidine kinase activity
L7754_RS20500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L7754_RS20540	COG2205	protein histidine kinase activity
L7754_RS20545	COG0745	RESPONSE REGULATOR receiver
L7754_RS20575	COG2226	methyltransferase
L7754_RS20585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L7754_RS20595	COG1215	transferase activity, transferring glycosyl groups
L7754_RS20615	COG0697	spore germination
L7754_RS20645	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L7754_RS20650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L7754_RS20655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L7754_RS20665	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L7754_RS20680	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L7754_RS20690	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L7754_RS20700	COG0151	Belongs to the GarS family
L7754_RS20725	COG0210	DNA helicase
L7754_RS20735	COG4851	CamS sex pheromone cAM373 precursor
L7754_RS20750	COG1335	isochorismatase
L7754_RS20760	COG2011	ABC-type metal ion transport system permease component
L7754_RS20765	COG1464	Belongs to the NlpA lipoprotein family
L7754_RS20780	COG0003	Pfam Anion-transporting ATPase
L7754_RS20785	COG1846	Transcriptional regulator
L7754_RS20790	COG4682	membrane
L7754_RS20810	COG1597	lipid kinase activity
L7754_RS20820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L7754_RS20830	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS20835	COG2076	Multidrug Resistance protein
L7754_RS20845	COG2309	aminopeptidase activity
L7754_RS20865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS20875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L7754_RS20890	COG4807	Protein conserved in bacteria
L7754_RS20915	COG1757	Na H antiporter
L7754_RS20920	COG1473	amidohydrolase
L7754_RS20935	COG0450	alkyl hydroperoxide reductase
L7754_RS20955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS20960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS20965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS20970	COG0492	ferredoxin-NADP+ reductase activity
L7754_RS20980	COG0166	Belongs to the GPI family
L7754_RS21005	COG5002	protein histidine kinase activity
L7754_RS21025	COG3541	Predicted nucleotidyltransferase
L7754_RS21030	COG2814	Major facilitator Superfamily
L7754_RS21035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L7754_RS21035	COG0723	plastoquinol--plastocyanin reductase activity
L7754_RS21045	COG0765	amino acid transport
L7754_RS21050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L7754_RS21055	COG1126	abc transporter atp-binding protein
L7754_RS21060	COG0840	transmembrane signaling receptor activity
L7754_RS21085	COG0549	Belongs to the carbamate kinase family
L7754_RS21090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L7754_RS21100	COG0277	FAD linked oxidase domain protein
L7754_RS21105	COG0366	Alpha amylase catalytic
L7754_RS21110	COG1263	PTS System
L7754_RS21110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L7754_RS21110	COG2190	(PTS) system
L7754_RS21140	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
L7754_RS21160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L7754_RS21165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L7754_RS21170	COG1116	anion transmembrane transporter activity
L7754_RS21220	COG2270	Major facilitator Superfamily
L7754_RS21250	COG2310	stress, protein
L7754_RS21255	COG2310	stress, protein
L7754_RS21260	COG2310	stress, protein
L7754_RS21265	COG0861	Integral membrane protein TerC family
L7754_RS21275	COG3853	Toxic anion resistance protein (TelA)
L7754_RS21290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L7754_RS21300	COG1295	ribonuclease BN
L7754_RS21305	COG2217	Heavy metal translocating P-type atpase
L7754_RS21310	COG0697	spore germination
L7754_RS21320	COG0681	Belongs to the peptidase S26 family
L7754_RS21330	COG0586	Pfam SNARE associated Golgi protein
L7754_RS21345	COG3871	stress protein (general stress protein 26)
L7754_RS21350	COG0387	Pfam Sodium calcium exchanger
L7754_RS21360	COG0535	radical SAM domain protein
L7754_RS21380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
L7754_RS21385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L7754_RS21400	COG3829	transcription factor binding
L7754_RS21410	COG0833	amino acid
L7754_RS21415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L7754_RS21445	COG1263	PTS System
L7754_RS21445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L7754_RS21450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L7754_RS21465	COG0463	Glycosyl transferase, family 2
L7754_RS21475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
L7754_RS21475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L7754_RS21495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L7754_RS21515	COG1228	amidohydrolase
L7754_RS21520	COG1090	epimerase
L7754_RS21550	COG1988	membrane-bound metal-dependent
L7754_RS21555	COG1194	a g-specific adenine glycosylase
L7754_RS21580	COG1132	(ABC) transporter
L7754_RS21585	COG4129	membrane
L7754_RS21590	COG0067	glutamate synthase
L7754_RS21590	COG0070	glutamate synthase
L7754_RS21590	COG0069	glutamate synthase activity
L7754_RS21600	COG4555	ABC transporter
L7754_RS21620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L7754_RS21625	COG0735	belongs to the Fur family
L7754_RS21745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
L7754_RS21770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L7754_RS21780	COG2766	serine protein kinase
L7754_RS21800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L7754_RS21810	COG1585	Membrane protein implicated in regulation of membrane protease activity
L7754_RS21815	COG2268	Band 7 protein
L7754_RS21825	COG3290	protein histidine kinase activity
L7754_RS21830	COG4565	transcriptional regulatory protein
L7754_RS21835	COG2851	Citrate transporter
L7754_RS21860	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L7754_RS21865	COG3842	ATPase activity
L7754_RS21870	COG1175	transmembrane transport
L7754_RS21875	COG0395	ABC-type sugar transport system, permease component
L7754_RS21885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L7754_RS21890	COG0745	RESPONSE REGULATOR receiver
L7754_RS21895	COG5002	protein histidine kinase activity
L7754_RS21905	COG4990	cell redox homeostasis
L7754_RS21915	COG3290	protein histidine kinase activity
L7754_RS21920	COG4565	transcriptional regulatory protein
L7754_RS21925	COG3493	citrate carrier protein
L7754_RS21930	COG0281	malic enzyme
L7754_RS21940	COG0697	spore germination
L7754_RS21945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L7754_RS21955	COG5002	protein histidine kinase activity
L7754_RS21970	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L7754_RS21975	COG3383	formate dehydrogenase (NAD+) activity
L7754_RS21980	COG2427	Protein of unknown function (DUF1641)
L7754_RS21995	COG0531	amino acid
L7754_RS22000	COG0640	Transcriptional regulator
L7754_RS22005	COG2217	Heavy metal translocating P-type atpase
L7754_RS22010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L7754_RS22025	COG3227	Zinc metalloprotease (Elastase)
L7754_RS22045	COG2720	vancomycin resistance protein
L7754_RS22050	COG1316	TRANSCRIPTIONal
L7754_RS22055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
L7754_RS22060	COG0346	lactoylglutathione lyase activity
L7754_RS22065	COG1253	flavin adenine dinucleotide binding
L7754_RS22070	COG1027	Aspartate ammonia-lyase
L7754_RS22075	COG1620	l-lactate permease
L7754_RS22090	COG3104	oligopeptide transport
L7754_RS22095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
L7754_RS22100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS22105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L7754_RS22125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L7754_RS22135	COG4548	von Willebrand factor, type A
L7754_RS22140	COG0714	Associated with various cellular activities
L7754_RS22160	COG0531	amino acid
L7754_RS22165	COG2188	Transcriptional regulator
L7754_RS22170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L7754_RS22170	COG1263	PTS System
L7754_RS22175	COG0366	Alpha amylase catalytic
L7754_RS22190	COG0697	spore germination
L7754_RS22200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L7754_RS22205	COG1115	amino acid carrier protein
L7754_RS22210	COG1126	abc transporter atp-binding protein
L7754_RS22215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L7754_RS22220	COG0765	amino acid transport
L7754_RS22225	COG0765	amino acid transport
L7754_RS22230	COG0833	amino acid
L7754_RS22255	COG2378	regulation of single-species biofilm formation
L7754_RS22260	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L7754_RS22265	COG5002	protein histidine kinase activity
L7754_RS22290	COG0659	secondary active sulfate transmembrane transporter activity
L7754_RS22305	COG2271	Major facilitator Superfamily
L7754_RS22310	COG1846	Transcriptional regulator
L7754_RS22315	COG0477	Major facilitator Superfamily
L7754_RS22320	COG1609	Transcriptional regulator
L7754_RS22325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L7754_RS22340	COG1172	Belongs to the binding-protein-dependent transport system permease family
L7754_RS22345	COG1879	ABC-type sugar transport system periplasmic component
L7754_RS22370	COG1063	alcohol dehydrogenase
L7754_RS22420	COG0840	transmembrane signaling receptor activity
L7754_RS22425	COG3584	3D domain protein
L7754_RS22425	COG1388	LysM domain
L7754_RS22430	COG1476	TRANSCRIPTIONal
L7754_RS22450	COG3104	oligopeptide transport
L7754_RS22455	COG1114	Component of the transport system for branched-chain amino acids
L7754_RS22470	COG1113	amino acid transport
L7754_RS22475	COG2252	PERMEase
L7754_RS22490	COG2153	protein acetylation
L7754_RS22500	COG0569	domain protein
L7754_RS22500	COG0475	glutathione-regulated potassium exporter activity
L7754_RS22515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L7754_RS22525	COG0833	amino acid
L7754_RS22530	COG4990	cell redox homeostasis
L7754_RS22545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L7754_RS22550	COG0697	spore germination
L7754_RS22555	COG0531	amino acid
L7754_RS22565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L7754_RS22570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L7754_RS22575	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
L7754_RS22575	COG1918	ferrous iron import across plasma membrane
L7754_RS22580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L7754_RS22585	COG0573	inorganic phosphate transmembrane transporter activity
L7754_RS22590	COG0581	inorganic phosphate transmembrane transporter activity
L7754_RS22600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L7754_RS22720	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
L7754_RS22740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L7754_RS22745	COG1116	anion transmembrane transporter activity
L7754_RS22750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L7754_RS22755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L7754_RS22760	COG0352	thiamine-phosphate diphosphorylase activity
L7754_RS22765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L7754_RS22770	COG2104	thiamine diphosphate biosynthetic process
L7754_RS22780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
L7754_RS22785	COG0351	phosphomethylpyrimidine kinase
L7754_RS22825	COG2205	protein histidine kinase activity
L7754_RS22830	COG2814	Major facilitator Superfamily
L7754_RS22835	COG1846	Transcriptional regulator
L7754_RS22860	COG1136	(ABC) transporter
L7754_RS22875	COG1172	Belongs to the binding-protein-dependent transport system permease family
L7754_RS22880	COG1129	ABC transporter
L7754_RS22890	COG2252	PERMEase
L7754_RS22895	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS22910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L7754_RS22915	COG1621	beta-fructofuranosidase activity
L7754_RS22920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L7754_RS22920	COG1263	PTS System
L7754_RS22925	COG1609	Transcriptional regulator
L7754_RS22975	COG0778	Nitroreductase
L7754_RS22980	COG2719	SpoVR family
L7754_RS22990	COG1414	Transcriptional regulator
L7754_RS23005	COG0446	pyridine nucleotide-disulphide oxidoreductase
L7754_RS23010	COG1937	Protein conserved in bacteria
L7754_RS23015	COG0425	Belongs to the sulfur carrier protein TusA family
L7754_RS23015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L7754_RS23020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L7754_RS23020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS23025	COG0425	Belongs to the sulfur carrier protein TusA family
L7754_RS23030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L7754_RS23030	COG0425	Belongs to the sulfur carrier protein TusA family
L7754_RS23035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L7754_RS23040	COG2210	Belongs to the sulfur carrier protein TusA family
L7754_RS23045	COG0730	response to heat
L7754_RS23055	COG1316	TRANSCRIPTIONal
L7754_RS23060	COG0604	alcohol dehydrogenase
L7754_RS23065	COG1283	sodium-dependent phosphate transmembrane transporter activity
L7754_RS23080	COG3711	transcriptional antiterminator
L7754_RS23080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L7754_RS23085	COG1447	Phosphotransferase system cellobiose-specific component IIA
L7754_RS23090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L7754_RS23110	COG1388	LysM domain
L7754_RS23110	COG3584	3D domain protein
L7754_RS23115	COG0577	efflux transmembrane transporter activity
L7754_RS23120	COG1136	(ABC) transporter
L7754_RS23130	COG5522	Integral membrane protein (intg_mem_TP0381)
L7754_RS23145	COG1114	Component of the transport system for branched-chain amino acids
L7754_RS23150	COG3546	catalase activity
L7754_RS23185	COG0586	Pfam SNARE associated Golgi protein
L7754_RS23225	COG0531	amino acid
L7754_RS23230	COG0475	glutathione-regulated potassium exporter activity
L7754_RS23240	COG1737	Transcriptional regulator
L7754_RS23250	COG1263	PTS System
L7754_RS23250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L7754_RS23260	COG2259	Doxx family
L7754_RS23280	COG1522	sequence-specific DNA binding
L7754_RS23285	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
L7754_RS23285	COG0165	Argininosuccinate lyase
L7754_RS23290	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS23310	COG1309	transcriptional regulator
L7754_RS23315	COG2814	Major facilitator Superfamily
L7754_RS23320	COG1733	regulation of RNA biosynthetic process
L7754_RS23330	COG2249	NAD(P)H dehydrogenase (quinone) activity
L7754_RS23335	COG4533	DNA binding
L7754_RS23340	COG2211	Major facilitator Superfamily
L7754_RS23355	COG0693	protein deglycase activity
L7754_RS23360	COG0693	protein deglycase activity
L7754_RS23360	COG0753	catalase activity
L7754_RS23370	COG0531	amino acid
L7754_RS23375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L7754_RS23385	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS23390	COG1132	(ABC) transporter
L7754_RS23395	COG1132	(ABC) transporter
L7754_RS23400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L7754_RS23405	COG0765	amino acid transport
L7754_RS23410	COG1126	abc transporter atp-binding protein
L7754_RS23425	COG0189	ligase activity
L7754_RS23445	COG4585	Histidine kinase
L7754_RS23450	COG2197	response regulator
L7754_RS23455	COG0028	Belongs to the TPP enzyme family
L7754_RS23460	COG3527	Alpha-acetolactate decarboxylase
L7754_RS23470	COG0561	phosphatase activity
L7754_RS23480	COG3409	Peptidoglycan-binding domain 1 protein
L7754_RS23480	COG5632	N-Acetylmuramoyl-L-alanine amidase
L7754_RS23485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L7754_RS23490	COG0318	PFAM AMP-dependent synthetase and ligase
L7754_RS23505	COG0659	secondary active sulfate transmembrane transporter activity
L7754_RS23510	COG2244	polysaccharide biosynthetic process
L7754_RS23530	COG1024	Enoyl-CoA hydratase
L7754_RS23550	COG1363	Peptidase, m42
L7754_RS23585	COG0601	transmembrane transport
L7754_RS23590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L7754_RS23595	COG0444	Belongs to the ABC transporter superfamily
L7754_RS23600	COG4608	Belongs to the ABC transporter superfamily
L7754_RS23610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L7754_RS23630	COG0457	Tetratricopeptide repeat
L7754_RS23865	COG0477	Major facilitator Superfamily
L7754_RS23870	COG3290	protein histidine kinase activity
L7754_RS23875	COG4565	transcriptional regulatory protein
L7754_RS23880	COG3181	Tripartite tricarboxylate transporter family receptor
L7754_RS23885	COG0494	nUDIX hydrolase
L7754_RS23900	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
L7754_RS23935	COG0305	Participates in initiation and elongation during chromosome replication
L7754_RS23960	COG0477	Major facilitator Superfamily
L7754_RS23975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS23980	COG3344	reverse transcriptase
L7754_RS24005	COG1073	alpha beta
L7754_RS24045	COG1183	phosphatidylcholine synthase activity
L7754_RS24060	COG2376	Dihydroxyacetone kinase
L7754_RS24070	COG2376	Dihydroxyacetone kinase
L7754_RS24110	COG1388	LysM domain
L7754_RS24110	COG3584	3D domain protein
L7754_RS24115	COG0791	NLP P60 protein
L7754_RS24115	COG1388	LysM domain
L7754_RS24125	COG2373	Large extracellular alpha-helical protein
L7754_RS24145	COG0596	Alpha beta hydrolase
L7754_RS24215	COG1191	sigma factor activity
L7754_RS24225	COG2208	phosphoserine phosphatase activity
L7754_RS24230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
L7754_RS24235	COG2205	protein histidine kinase activity
L7754_RS24235	COG0784	Response regulator, receiver
L7754_RS24235	COG5002	protein histidine kinase activity
L7754_RS24280	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
L7754_RS24300	COG0420	3'-5' exonuclease activity
L7754_RS24305	COG4717	serine-type aminopeptidase activity
L7754_RS24315	COG0346	lactoylglutathione lyase activity
L7754_RS24320	COG0346	lactoylglutathione lyase activity
L7754_RS24325	COG0457	Tetratricopeptide repeat
L7754_RS24335	COG2267	carboxylic ester hydrolase activity
L7754_RS24360	COG2140	Oxalate decarboxylase
L7754_RS24365	COG3620	sequence-specific DNA binding
L7754_RS24370	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
L7754_RS24375	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L7754_RS24385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L7754_RS24390	COG1695	Transcriptional regulator
L7754_RS24420	COG3973	AAA domain
L7754_RS24430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L7754_RS24450	COG4980	gas vesicle protein
L7754_RS24455	COG0537	adenosine 5'-monophosphoramidase activity
L7754_RS24460	COG1131	(ABC) transporter
L7754_RS24465	COG4473	ABC transporter
L7754_RS24490	COG3402	PFAM membrane-flanked domain
L7754_RS24495	COG3428	Bacterial PH domain
L7754_RS24525	COG0697	spore germination
L7754_RS24530	COG3402	PFAM membrane-flanked domain
L7754_RS24535	COG3428	Bacterial PH domain
L7754_RS24540	COG2329	Antibiotic biosynthesis monooxygenase
L7754_RS24545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L7754_RS24560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
L7754_RS24595	COG1309	transcriptional regulator
L7754_RS24600	COG1511	domain protein
L7754_RS24620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L7754_RS24625	COG1609	Transcriptional regulator
L7754_RS24635	COG1234	tRNA 3'-trailer cleavage
L7754_RS24640	COG0095	Lipoate-protein ligase
L7754_RS24650	COG0318	PFAM AMP-dependent synthetase and ligase
L7754_RS24660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L7754_RS24670	COG4208	sulfate ABC transporter
L7754_RS24825	COG1073	alpha beta
L7754_RS24830	COG1408	metallophosphoesterase
L7754_RS24835	COG1078	dGTPase activity
L7754_RS24845	COG1595	DNA-templated transcription, initiation
L7754_RS24850	COG2207	Transcriptional regulator
L7754_RS24850	COG3708	Transcriptional regulator
L7754_RS24855	COG2205	protein histidine kinase activity
L7754_RS24860	COG0745	RESPONSE REGULATOR receiver
L7754_RS24880	COG0501	Belongs to the peptidase M48B family
L7754_RS24885	COG0840	transmembrane signaling receptor activity
L7754_RS24890	COG3693	PFAM glycoside hydrolase, family 10
L7754_RS24900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L7754_RS24905	COG2224	Isocitrate lyase
L7754_RS24945	COG0398	Pfam SNARE associated Golgi protein
L7754_RS25005	COG0179	Fumarylacetoacetate (FAA) hydrolase
L7754_RS25030	COG0367	asparagine synthase
L7754_RS25040	COG0753	catalase activity
L7754_RS25045	COG0004	ammonium transporteR
L7754_RS25065	COG2996	Protein conserved in bacteria
L7754_RS25135	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS25150	COG0561	phosphatase activity
L7754_RS25170	COG2267	carboxylic ester hydrolase activity
L7754_RS25190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L7754_RS25195	COG5504	Zn-dependent protease
L7754_RS25205	COG0180	Tryptophanyl-tRNA synthetase
L7754_RS25215	COG4166	transmembrane transport
L7754_RS25220	COG0601	transmembrane transport
L7754_RS25225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L7754_RS25230	COG0444	Belongs to the ABC transporter superfamily
L7754_RS25235	COG4608	Belongs to the ABC transporter superfamily
L7754_RS25240	COG0534	Mate efflux family protein
L7754_RS25245	COG4166	transmembrane transport
L7754_RS25260	COG0861	Integral membrane protein TerC family
L7754_RS25280	COG1164	Oligoendopeptidase f
L7754_RS25295	COG2346	COG2346, Truncated hemoglobins
L7754_RS25300	COG4116	CYTH
L7754_RS25310	COG2357	RelA SpoT domain protein
L7754_RS25320	COG0564	pseudouridine synthase activity
L7754_RS25335	COG0772	Belongs to the SEDS family
L7754_RS25340	COG1216	Glycosyl transferase, family 2
L7754_RS25360	COG0457	Tetratricopeptide repeat
L7754_RS25360	COG0463	Glycosyl transferase, family 2
L7754_RS25380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
L7754_RS25395	COG1091	dTDP-4-dehydrorhamnose reductase activity
L7754_RS25440	COG2153	protein acetylation
L7754_RS25450	COG2382	esterase
L7754_RS25470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L7754_RS25480	COG0512	Glutamine amidotransferase of anthranilate synthase
L7754_RS25480	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L7754_RS25515	COG1620	l-lactate permease
L7754_RS25520	COG5634	Uncharacterized conserved protein (DUF2278)
L7754_RS25570	COG0508	dehydrogenase complex catalyzes the overall conversion of
L7754_RS25580	COG1476	TRANSCRIPTIONal
L7754_RS25635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
L7754_RS25650	COG4152	abc transporter atp-binding protein
L7754_RS25655	COG1668	transmembrane transport
L7754_RS25685	COG1686	Belongs to the peptidase S11 family
L7754_RS25690	COG0681	Belongs to the peptidase S26 family
L7754_RS25725	COG1012	belongs to the aldehyde dehydrogenase family
L7754_RS25735	COG1176	ABC-type spermidine putrescine transport system, permease component I
L7754_RS25740	COG1177	transmembrane transport
L7754_RS25755	COG2409	Drug exporters of the RND superfamily
L7754_RS25765	COG0564	pseudouridine synthase activity
L7754_RS25775	COG2340	Cysteine-rich secretory protein family
L7754_RS25780	COG0247	lactate metabolic process
L7754_RS25785	COG0277	FAD linked oxidase domain protein
L7754_RS25790	COG3835	regulator
L7754_RS25800	COG0745	RESPONSE REGULATOR receiver
L7754_RS25805	COG5002	protein histidine kinase activity
L7754_RS25810	COG2186	Transcriptional regulator
L7754_RS25830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L7754_RS25840	COG2116	formate transmembrane transporter activity
L7754_RS25845	COG0861	Integral membrane protein TerC family
L7754_RS25850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L7754_RS25860	COG2030	dehydratase
L7754_RS25880	COG1028	Short-chain dehydrogenase reductase Sdr
L7754_RS25885	COG3243	poly(R)-hydroxyalkanoic acid synthase
L7754_RS25895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L7754_RS25910	COG1840	ABC-type Fe3 transport system, periplasmic component
L7754_RS25915	COG3842	ATPase activity
L7754_RS25940	COG1349	DNA-binding transcription factor activity
L7754_RS25950	COG0235	Class ii aldolase
L7754_RS25960	COG2861	carbohydrate metabolic process
L7754_RS25970	COG3852	Histidine kinase
L7754_RS25975	COG1846	Transcriptional regulator
L7754_RS25985	COG2318	DinB family
L7754_RS25995	COG5002	protein histidine kinase activity
L7754_RS26005	COG0720	synthase
L7754_RS26020	COG4873	Protein conserved in bacteria
L7754_RS26050	COG1780	Probably involved in ribonucleotide reductase function
L7754_RS26055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L7754_RS26060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L7754_RS26065	COG1725	Transcriptional regulator
L7754_RS26070	COG1131	(ABC) transporter
L7754_RS26080	COG1131	(ABC) transporter
L7754_RS26100	COG1522	sequence-specific DNA binding
L7754_RS26110	COG1335	isochorismatase
L7754_RS26120	COG1619	proteins homologs of microcin C7 resistance protein MccF
L7754_RS26125	COG2070	2-Nitropropane dioxygenase
L7754_RS26130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L7754_RS26140	COG1696	Membrane protein involved in D-alanine export
L7754_RS26165	COG0716	FMN binding
L7754_RS26180	COG3173	Aminoglycoside phosphotransferase
L7754_RS26220	COG1846	Transcriptional regulator
L7754_RS26230	COG1301	dicarboxylic acid transport
L7754_RS26235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L7754_RS26240	COG4709	membrane
L7754_RS26245	COG3874	Sporulation protein YtfJ
L7754_RS26265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L7754_RS26270	COG0028	Belongs to the TPP enzyme family
L7754_RS26275	COG0440	acetolactate synthase activity
L7754_RS26350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
L7754_RS26365	COG1183	phosphatidylcholine synthase activity
L7754_RS26370	COG1368	sulfuric ester hydrolase activity
L7754_RS26380	COG0019	diaminopimelate decarboxylase activity
L7754_RS26400	COG0529	Catalyzes the synthesis of activated sulfate
L7754_RS26405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L7754_RS26425	COG1648	precorrin-2 dehydrogenase activity
L7754_RS26430	COG0733	neurotransmitter:sodium symporter activity
L7754_RS26455	COG1757	Na H antiporter
L7754_RS26470	COG4758	membrane
L7754_RS26475	COG4585	Histidine kinase
L7754_RS26480	COG2197	response regulator
L7754_RS26490	COG1114	Component of the transport system for branched-chain amino acids
L7754_RS26540	COG0730	response to heat
L7754_RS26545	COG0306	phosphate transporter
L7754_RS26550	COG1392	Phosphate transport regulator
L7754_RS26555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L7754_RS26570	COG3852	Histidine kinase
L7754_RS26575	COG1801	Protein of unknown function DUF72
L7754_RS26585	COG0582	viral genome integration into host DNA
L7754_RS26590	COG5002	protein histidine kinase activity
L7754_RS26605	COG0392	lysyltransferase activity
L7754_RS26605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
L7754_RS26620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L7754_RS26625	COG1686	Belongs to the peptidase S11 family
L7754_RS26630	COG2715	membrane protein required for spore maturation
L7754_RS26635	COG0700	Nucleoside recognition
L7754_RS26640	COG1187	pseudouridine synthase activity
L7754_RS26650	COG1333	cytochrome c biogenesis protein
L7754_RS26655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
L7754_RS26660	COG0745	RESPONSE REGULATOR receiver
L7754_RS26665	COG5002	protein histidine kinase activity
L7754_RS26670	COG2096	Adenosyltransferase
L7754_RS26685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L7754_RS26690	COG1141	Ferredoxin
L7754_RS26700	COG0514	ATP-dependent DNA helicase (RecQ)
L7754_RS26705	COG1266	CAAX protease self-immunity
L7754_RS26715	COG1408	metallophosphoesterase
L7754_RS26720	COG0789	Transcriptional regulator
L7754_RS26730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L7754_RS26750	COG0492	ferredoxin-NADP+ reductase activity
L7754_RS26755	COG0252	asparaginase activity
L7754_RS26825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L7754_RS26840	COG0142	geranyltranstransferase activity
L7754_RS26850	COG0142	geranyltranstransferase activity
L7754_RS26875	COG0457	Tetratricopeptide repeat
L7754_RS26895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L7754_RS26900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
L7754_RS26900	COG2010	Cytochrome c
L7754_RS26905	COG4347	Protein of unknown function (DUF1405)
L7754_RS26920	COG2738	Putative neutral zinc metallopeptidase
L7754_RS26930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L7754_RS26935	COG1694	Mazg nucleotide pyrophosphohydrolase
L7754_RS26955	COG0438	transferase activity, transferring glycosyl groups
L7754_RS26990	COG1199	ATP-dependent helicase activity
L7754_RS26990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L7754_RS27010	COG3935	DnaD domain protein
L7754_RS27015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L7754_RS27025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L7754_RS27025	COG4499	WXG100 protein secretion system (Wss), protein YukC
L7754_RS27080	COG0116	Belongs to the methyltransferase superfamily
L7754_RS27090	COG1199	ATP-dependent helicase activity
L7754_RS27095	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
L7754_RS27105	COG0024	Methionine aminopeptidase
L7754_RS27115	COG2233	PERMEase
L7754_RS27120	COG2311	Membrane
L7754_RS27125	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
L7754_RS27135	COG0456	acetyltransferase
L7754_RS27185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L7754_RS27200	COG3944	biosynthesis protein
L7754_RS27210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L7754_RS27225	COG1215	transferase activity, transferring glycosyl groups
L7754_RS27230	COG0438	transferase activity, transferring glycosyl groups
L7754_RS27270	COG2002	toxin-antitoxin pair type II binding
L7754_RS27350	COG0582	viral genome integration into host DNA
L7754_RS27365	COG4626	Terminase
L7754_RS27365	COG1802	Transcriptional regulator
L7754_RS27375	COG0740	serine-type endopeptidase activity
L7754_RS27450	COG5632	N-Acetylmuramoyl-L-alanine amidase
L7754_RS27510	COG1335	isochorismatase
L7754_RS27515	COG4990	cell redox homeostasis
L7754_RS27520	COG0745	RESPONSE REGULATOR receiver
L7754_RS27575	COG0798	PFAM Bile acid sodium symporter
L7754_RS27580	COG0640	Transcriptional regulator
L7754_RS27600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L7754_RS27610	COG3620	sequence-specific DNA binding
L7754_RS27615	COG0306	phosphate transporter
L7754_RS27620	COG0640	Transcriptional regulator
L7754_RS27635	COG1846	Transcriptional regulator
L7754_RS27675	COG2217	Heavy metal translocating P-type atpase
L7754_RS27680	COG1937	Protein conserved in bacteria
L7754_RS27685	COG3443	Belongs to the bacterial solute-binding protein 9 family
L7754_RS27685	COG0803	Belongs to the bacterial solute-binding protein 9 family
L7754_RS27705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L7754_RS27745	COG3118	belongs to the thioredoxin family
L7754_RS27755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L7754_RS27760	COG0765	amino acid transport
L7754_RS27765	COG1126	abc transporter atp-binding protein
L7754_RS27770	COG2304	oxidoreductase activity
L7754_RS27775	COG2132	Multicopper oxidase
L7754_RS27780	COG0745	RESPONSE REGULATOR receiver
L7754_RS27785	COG5002	protein histidine kinase activity
L7754_RS27795	COG0860	N-Acetylmuramoyl-L-alanine amidase
L7754_RS27805	COG4974	Belongs to the 'phage' integrase family
L7754_RS27820	COG0457	Tetratricopeptide repeat
L7754_RS27940	COG3344	reverse transcriptase
L7754_RS27950	COG3344	reverse transcriptase
L7754_RS27970	COG3344	reverse transcriptase
L7754_RS28020	COG1396	sequence-specific DNA binding
L7754_RS28055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L7754_RS28060	COG0582	viral genome integration into host DNA
L7754_RS28090	COG2003	Belongs to the UPF0758 family
L7754_RS28105	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
L7754_RS28170	COG3397	chitin binding
L7754_RS28205	COG0791	NLP P60 protein
L7754_RS28205	COG1388	LysM domain
L7754_RS28205	COG3103	Sh3 type 3 domain protein
L7754_RS28250	COG0640	Transcriptional regulator
L7754_RS28375	COG3344	reverse transcriptase
L7754_RS28510	COG3344	reverse transcriptase
L7754_RS28620	COG4962	Type ii secretion system protein e
L7754_RS28705	COG0640	Transcriptional regulator
L7754_RS28720	COG2072	flavoprotein involved in K transport
L7754_RS28730	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
L7754_RS28735	COG0589	response to stress
L7754_RS28740	COG0659	secondary active sulfate transmembrane transporter activity
L7754_RS28745	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L7754_RS28760	COG0659	secondary active sulfate transmembrane transporter activity
L7754_RS28775	COG2824	Alkylphosphonate utilization operon protein PhnA
L7754_RS28795	COG0640	Transcriptional regulator
L7754_RS28800	COG0798	PFAM Bile acid sodium symporter
L7754_RS28890	COG3344	reverse transcriptase
L7754_RS28975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L7754_RS28990	COG1063	alcohol dehydrogenase
L7754_RS28995	COG1733	regulation of RNA biosynthetic process
L7754_RS29005	COG3791	Glutathione-dependent formaldehyde-activating
L7754_RS29020	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L7754_RS29025	COG1181	Belongs to the D-alanine--D-alanine ligase family
L7754_RS29025	COG2918	glutathione biosynthetic process
L7754_RS29065	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
L7754_RS29110	COG2311	Membrane
L7754_RS29180	COG2002	toxin-antitoxin pair type II binding
L7754_RS29215	COG4974	Belongs to the 'phage' integrase family
L7754_RS29240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L7754_RS29270	COG4166	transmembrane transport
L7754_RS29285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L7754_RS29355	COG0789	Transcriptional regulator