locus-tag	class	description
CSW12_RS00020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CSW12_RS00025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSW12_RS00030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSW12_RS00040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSW12_RS00055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CSW12_RS00065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSW12_RS00075	COG0151	Belongs to the GarS family
CSW12_RS00085	COG0583	DNA-binding transcription factor activity
CSW12_RS00110	COG0210	DNA helicase
CSW12_RS00120	COG4851	CamS sex pheromone cAM373 precursor
CSW12_RS00140	COG1335	isochorismatase
CSW12_RS00155	COG2011	ABC-type metal ion transport system permease component
CSW12_RS00160	COG1464	Belongs to the NlpA lipoprotein family
CSW12_RS00175	COG1396	sequence-specific DNA binding
CSW12_RS00205	COG1484	DNA-dependent DNA replication
CSW12_RS00225	COG3617	BRO family, N-terminal domain
CSW12_RS00245	COG0582	viral genome integration into host DNA
CSW12_RS00365	COG3547	Transposase (IS116 IS110 IS902 family)
CSW12_RS00435	COG1597	lipid kinase activity
CSW12_RS00445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSW12_RS00455	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS00460	COG2076	Multidrug Resistance protein
CSW12_RS00470	COG2309	aminopeptidase activity
CSW12_RS00485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS00495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW12_RS00510	COG4807	Protein conserved in bacteria
CSW12_RS00535	COG1757	Na H antiporter
CSW12_RS00540	COG1473	amidohydrolase
CSW12_RS00555	COG0450	alkyl hydroperoxide reductase
CSW12_RS00575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS00580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS00585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS00595	COG0492	ferredoxin-NADP+ reductase activity
CSW12_RS00610	COG0166	Belongs to the GPI family
CSW12_RS00635	COG5002	protein histidine kinase activity
CSW12_RS00655	COG3541	Predicted nucleotidyltransferase
CSW12_RS00660	COG2814	Major facilitator Superfamily
CSW12_RS00665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_RS00665	COG0723	plastoquinol--plastocyanin reductase activity
CSW12_RS00675	COG0765	amino acid transport
CSW12_RS00680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_RS00690	COG0840	transmembrane signaling receptor activity
CSW12_RS00715	COG0549	Belongs to the carbamate kinase family
CSW12_RS00720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW12_RS00735	COG0277	FAD linked oxidase domain protein
CSW12_RS00740	COG0366	Alpha amylase catalytic
CSW12_RS00745	COG1263	PTS System
CSW12_RS00745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_RS00745	COG2190	(PTS) system
CSW12_RS00780	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CSW12_RS00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_RS00805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_RS00810	COG1116	anion transmembrane transporter activity
CSW12_RS00815	COG0488	(ABC) transporter
CSW12_RS00865	COG2270	Major facilitator Superfamily
CSW12_RS00895	COG2310	stress, protein
CSW12_RS00900	COG2310	stress, protein
CSW12_RS00905	COG2310	stress, protein
CSW12_RS00910	COG0861	Integral membrane protein TerC family
CSW12_RS00920	COG3853	Toxic anion resistance protein (TelA)
CSW12_RS00935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSW12_RS00945	COG1295	ribonuclease BN
CSW12_RS00955	COG2217	Heavy metal translocating P-type atpase
CSW12_RS00960	COG0697	spore germination
CSW12_RS00980	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS00995	COG3871	stress protein (general stress protein 26)
CSW12_RS01010	COG0535	radical SAM domain protein
CSW12_RS01030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CSW12_RS01035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CSW12_RS01050	COG3829	transcription factor binding
CSW12_RS01060	COG0833	amino acid
CSW12_RS01070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW12_RS01105	COG1263	PTS System
CSW12_RS01105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_RS01110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_RS01125	COG1216	Glycosyl transferase, family 2
CSW12_RS01135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CSW12_RS01135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW12_RS01140	COG0463	Glycosyl transferase, family 2
CSW12_RS01155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CSW12_RS01175	COG1228	amidohydrolase
CSW12_RS01180	COG1090	epimerase
CSW12_RS01210	COG1988	membrane-bound metal-dependent
CSW12_RS01215	COG1194	a g-specific adenine glycosylase
CSW12_RS01235	COG3557	Belongs to the UPF0374 family
CSW12_RS01240	COG1132	(ABC) transporter
CSW12_RS01245	COG4129	membrane
CSW12_RS01250	COG0069	glutamate synthase activity
CSW12_RS01250	COG0067	glutamate synthase
CSW12_RS01250	COG0070	glutamate synthase
CSW12_RS01260	COG4555	ABC transporter
CSW12_RS01280	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSW12_RS01285	COG0735	belongs to the Fur family
CSW12_RS01410	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CSW12_RS01435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSW12_RS01440	COG1716	ATPase activity
CSW12_RS01440	COG5001	Diguanylate cyclase
CSW12_RS01450	COG2766	serine protein kinase
CSW12_RS01480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW12_RS01490	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSW12_RS01495	COG2268	Band 7 protein
CSW12_RS01505	COG3290	protein histidine kinase activity
CSW12_RS01510	COG4565	transcriptional regulatory protein
CSW12_RS01515	COG2851	Citrate transporter
CSW12_RS01540	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CSW12_RS01545	COG3842	ATPase activity
CSW12_RS01550	COG1175	transmembrane transport
CSW12_RS01555	COG0395	ABC-type sugar transport system, permease component
CSW12_RS01565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSW12_RS01570	COG0745	RESPONSE REGULATOR receiver
CSW12_RS01575	COG5002	protein histidine kinase activity
CSW12_RS01585	COG4990	cell redox homeostasis
CSW12_RS01595	COG3290	protein histidine kinase activity
CSW12_RS01600	COG4565	transcriptional regulatory protein
CSW12_RS01605	COG3493	citrate carrier protein
CSW12_RS01610	COG0281	malic enzyme
CSW12_RS01620	COG0697	spore germination
CSW12_RS01625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS01635	COG5002	protein histidine kinase activity
CSW12_RS01640	COG0745	RESPONSE REGULATOR receiver
CSW12_RS01655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSW12_RS01665	COG3383	formate dehydrogenase (NAD+) activity
CSW12_RS01670	COG2427	Protein of unknown function (DUF1641)
CSW12_RS01685	COG0531	amino acid
CSW12_RS01690	COG0640	Transcriptional regulator
CSW12_RS01695	COG2217	Heavy metal translocating P-type atpase
CSW12_RS01700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CSW12_RS01715	COG3227	Zinc metalloprotease (Elastase)
CSW12_RS01735	COG2720	vancomycin resistance protein
CSW12_RS01740	COG1316	TRANSCRIPTIONal
CSW12_RS01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS01750	COG0346	lactoylglutathione lyase activity
CSW12_RS01755	COG1253	flavin adenine dinucleotide binding
CSW12_RS01760	COG1027	Aspartate ammonia-lyase
CSW12_RS01765	COG1620	l-lactate permease
CSW12_RS01780	COG3104	oligopeptide transport
CSW12_RS01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS01795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS01805	COG2226	methyltransferase
CSW12_RS01815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW12_RS01825	COG4548	von Willebrand factor, type A
CSW12_RS01830	COG0714	Associated with various cellular activities
CSW12_RS01850	COG0531	amino acid
CSW12_RS01855	COG2188	Transcriptional regulator
CSW12_RS01860	COG1263	PTS System
CSW12_RS01860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_RS01865	COG0366	Alpha amylase catalytic
CSW12_RS01880	COG0697	spore germination
CSW12_RS01885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSW12_RS01890	COG1115	amino acid carrier protein
CSW12_RS01895	COG1126	abc transporter atp-binding protein
CSW12_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_RS01905	COG0765	amino acid transport
CSW12_RS01910	COG0765	amino acid transport
CSW12_RS01915	COG0833	amino acid
CSW12_RS01930	COG1595	DNA-templated transcription, initiation
CSW12_RS01940	COG2378	regulation of single-species biofilm formation
CSW12_RS01945	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CSW12_RS01955	COG5002	protein histidine kinase activity
CSW12_RS01970	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_RS01995	COG0601	transmembrane transport
CSW12_RS02000	COG4608	Belongs to the ABC transporter superfamily
CSW12_RS02010	COG2271	Major facilitator Superfamily
CSW12_RS02015	COG1846	Transcriptional regulator
CSW12_RS02020	COG0477	Major facilitator Superfamily
CSW12_RS02025	COG1609	Transcriptional regulator
CSW12_RS02030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSW12_RS02045	COG4974	Belongs to the 'phage' integrase family
CSW12_RS02250	COG4824	toxin secretion phage lysis holin
CSW12_RS02255	COG1388	LysM domain
CSW12_RS02255	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS02255	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_RS02300	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW12_RS02305	COG1879	ABC-type sugar transport system periplasmic component
CSW12_RS02435	COG0582	viral genome integration into host DNA
CSW12_RS02470	COG0740	serine-type endopeptidase activity
CSW12_RS02540	COG4824	toxin secretion phage lysis holin
CSW12_RS02615	COG0840	transmembrane signaling receptor activity
CSW12_RS02620	COG3584	3D domain protein
CSW12_RS02620	COG1388	LysM domain
CSW12_RS02625	COG1476	TRANSCRIPTIONal
CSW12_RS02645	COG3104	oligopeptide transport
CSW12_RS02650	COG1114	Component of the transport system for branched-chain amino acids
CSW12_RS02665	COG1113	amino acid transport
CSW12_RS02670	COG2252	PERMEase
CSW12_RS02685	COG2153	protein acetylation
CSW12_RS02695	COG0569	domain protein
CSW12_RS02695	COG0475	glutathione-regulated potassium exporter activity
CSW12_RS02710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSW12_RS02715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSW12_RS02720	COG0833	amino acid
CSW12_RS02725	COG4990	cell redox homeostasis
CSW12_RS02740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_RS02745	COG0697	spore germination
CSW12_RS02750	COG0531	amino acid
CSW12_RS02765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CSW12_RS02770	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CSW12_RS02775	COG1918	ferrous iron import across plasma membrane
CSW12_RS02775	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CSW12_RS02780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSW12_RS02785	COG0573	inorganic phosphate transmembrane transporter activity
CSW12_RS02790	COG0581	inorganic phosphate transmembrane transporter activity
CSW12_RS02800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSW12_RS02925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CSW12_RS02950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSW12_RS02955	COG1116	anion transmembrane transporter activity
CSW12_RS02960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_RS02965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_RS02970	COG0352	thiamine-phosphate diphosphorylase activity
CSW12_RS02975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_RS02980	COG2104	thiamine diphosphate biosynthetic process
CSW12_RS02990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_RS02995	COG0351	phosphomethylpyrimidine kinase
CSW12_RS03040	COG2205	protein histidine kinase activity
CSW12_RS03045	COG2814	Major facilitator Superfamily
CSW12_RS03050	COG1846	Transcriptional regulator
CSW12_RS03065	COG2252	PERMEase
CSW12_RS03070	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS03130	COG0778	Nitroreductase
CSW12_RS03135	COG2719	SpoVR family
CSW12_RS03175	COG1401	restriction endodeoxyribonuclease activity
CSW12_RS03175	COG1401	restriction endodeoxyribonuclease activity
CSW12_RS03190	COG1414	Transcriptional regulator
CSW12_RS03210	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSW12_RS03215	COG1937	Protein conserved in bacteria
CSW12_RS03220	COG0425	Belongs to the sulfur carrier protein TusA family
CSW12_RS03220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS03225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS03225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS03230	COG0425	Belongs to the sulfur carrier protein TusA family
CSW12_RS03235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS03245	COG2210	Belongs to the sulfur carrier protein TusA family
CSW12_RS03250	COG0730	response to heat
CSW12_RS03260	COG1316	TRANSCRIPTIONal
CSW12_RS03265	COG0604	alcohol dehydrogenase
CSW12_RS03270	COG1283	sodium-dependent phosphate transmembrane transporter activity
CSW12_RS03290	COG3711	transcriptional antiterminator
CSW12_RS03290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW12_RS03295	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW12_RS03300	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW12_RS03320	COG3584	3D domain protein
CSW12_RS03320	COG1388	LysM domain
CSW12_RS03325	COG0577	efflux transmembrane transporter activity
CSW12_RS03330	COG1136	(ABC) transporter
CSW12_RS03340	COG5522	Integral membrane protein (intg_mem_TP0381)
CSW12_RS03355	COG0577	efflux transmembrane transporter activity
CSW12_RS03360	COG1114	Component of the transport system for branched-chain amino acids
CSW12_RS03365	COG3546	catalase activity
CSW12_RS03400	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS03435	COG0531	amino acid
CSW12_RS03440	COG0475	glutathione-regulated potassium exporter activity
CSW12_RS03450	COG1737	Transcriptional regulator
CSW12_RS03460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_RS03460	COG1263	PTS System
CSW12_RS03470	COG2259	Doxx family
CSW12_RS03490	COG1522	sequence-specific DNA binding
CSW12_RS03495	COG0165	Argininosuccinate lyase
CSW12_RS03495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CSW12_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS03520	COG1309	transcriptional regulator
CSW12_RS03525	COG2814	Major facilitator Superfamily
CSW12_RS03530	COG1733	regulation of RNA biosynthetic process
CSW12_RS03550	COG0693	protein deglycase activity
CSW12_RS03555	COG0753	catalase activity
CSW12_RS03555	COG0693	protein deglycase activity
CSW12_RS03565	COG0531	amino acid
CSW12_RS03580	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS03600	COG1132	(ABC) transporter
CSW12_RS03605	COG1132	(ABC) transporter
CSW12_RS03615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_RS03620	COG0765	amino acid transport
CSW12_RS03625	COG1126	abc transporter atp-binding protein
CSW12_RS03640	COG0189	ligase activity
CSW12_RS03660	COG4585	Histidine kinase
CSW12_RS03665	COG2197	response regulator
CSW12_RS03685	COG0028	Belongs to the TPP enzyme family
CSW12_RS03690	COG3527	Alpha-acetolactate decarboxylase
CSW12_RS03705	COG0561	phosphatase activity
CSW12_RS03715	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS03715	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_RS03720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSW12_RS03740	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_RS03745	COG2244	polysaccharide biosynthetic process
CSW12_RS03775	COG1024	Enoyl-CoA hydratase
CSW12_RS03835	COG0601	transmembrane transport
CSW12_RS03840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_RS03845	COG0444	Belongs to the ABC transporter superfamily
CSW12_RS03850	COG4608	Belongs to the ABC transporter superfamily
CSW12_RS03860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS03890	COG0477	Major facilitator Superfamily
CSW12_RS03895	COG3290	protein histidine kinase activity
CSW12_RS03900	COG4565	transcriptional regulatory protein
CSW12_RS03905	COG3181	Tripartite tricarboxylate transporter family receptor
CSW12_RS03910	COG0494	nUDIX hydrolase
CSW12_RS03915	COG0513	Belongs to the DEAD box helicase family
CSW12_RS03925	COG1061	Type III restriction enzyme res subunit
CSW12_RS03940	COG0789	Transcriptional regulator
CSW12_RS03940	COG4978	Transcriptional regulator
CSW12_RS03960	COG0305	Participates in initiation and elongation during chromosome replication
CSW12_RS03995	COG0477	Major facilitator Superfamily
CSW12_RS04050	COG1073	alpha beta
CSW12_RS04095	COG1183	phosphatidylcholine synthase activity
CSW12_RS04110	COG2814	Major facilitator Superfamily
CSW12_RS04115	COG0640	Transcriptional regulator
CSW12_RS04130	COG2376	Dihydroxyacetone kinase
CSW12_RS04160	COG2376	Dihydroxyacetone kinase
CSW12_RS04205	COG0457	Tetratricopeptide repeat
CSW12_RS04215	COG2373	Large extracellular alpha-helical protein
CSW12_RS04260	COG3237	CsbD-like
CSW12_RS04295	COG1191	sigma factor activity
CSW12_RS04305	COG2208	phosphoserine phosphatase activity
CSW12_RS04315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW12_RS04320	COG5002	protein histidine kinase activity
CSW12_RS04320	COG2205	protein histidine kinase activity
CSW12_RS04320	COG0784	Response regulator, receiver
CSW12_RS04360	COG0604	alcohol dehydrogenase
CSW12_RS04360	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS04360	COG3321	synthase
CSW12_RS04365	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CSW12_RS04385	COG0420	3'-5' exonuclease activity
CSW12_RS04390	COG4717	serine-type aminopeptidase activity
CSW12_RS04405	COG1280	lysine exporter protein (LysE YggA)
CSW12_RS04410	COG0346	lactoylglutathione lyase activity
CSW12_RS04415	COG0346	lactoylglutathione lyase activity
CSW12_RS04420	COG0457	Tetratricopeptide repeat
CSW12_RS04430	COG2267	carboxylic ester hydrolase activity
CSW12_RS04445	COG2140	Oxalate decarboxylase
CSW12_RS04450	COG3620	sequence-specific DNA binding
CSW12_RS04455	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CSW12_RS04460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CSW12_RS04470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CSW12_RS04495	COG3973	AAA domain
CSW12_RS04530	COG4980	gas vesicle protein
CSW12_RS04535	COG0537	adenosine 5'-monophosphoramidase activity
CSW12_RS04545	COG1131	(ABC) transporter
CSW12_RS04550	COG4473	ABC transporter
CSW12_RS04565	COG1309	transcriptional regulator
CSW12_RS04575	COG3402	PFAM membrane-flanked domain
CSW12_RS04580	COG3428	Bacterial PH domain
CSW12_RS04640	COG0697	spore germination
CSW12_RS04645	COG3402	PFAM membrane-flanked domain
CSW12_RS04650	COG3428	Bacterial PH domain
CSW12_RS04655	COG2329	Antibiotic biosynthesis monooxygenase
CSW12_RS04660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_RS04675	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CSW12_RS04715	COG1309	transcriptional regulator
CSW12_RS04720	COG1511	domain protein
CSW12_RS04745	COG1609	Transcriptional regulator
CSW12_RS04755	COG1234	tRNA 3'-trailer cleavage
CSW12_RS04760	COG0095	Lipoate-protein ligase
CSW12_RS04770	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_RS04780	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSW12_RS04790	COG4208	sulfate ABC transporter
CSW12_RS04810	COG1408	metallophosphoesterase
CSW12_RS04825	COG1078	dGTPase activity
CSW12_RS04835	COG1595	DNA-templated transcription, initiation
CSW12_RS04840	COG3708	Transcriptional regulator
CSW12_RS04840	COG2207	Transcriptional regulator
CSW12_RS04855	COG2205	protein histidine kinase activity
CSW12_RS04860	COG0745	RESPONSE REGULATOR receiver
CSW12_RS04880	COG0501	Belongs to the peptidase M48B family
CSW12_RS04885	COG0840	transmembrane signaling receptor activity
CSW12_RS04895	COG3693	PFAM glycoside hydrolase, family 10
CSW12_RS04905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSW12_RS04915	COG2224	Isocitrate lyase
CSW12_RS04930	COG1278	Cold shock
CSW12_RS04945	COG4903	ComK protein
CSW12_RS04955	COG0398	Pfam SNARE associated Golgi protein
CSW12_RS05015	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSW12_RS05040	COG0367	asparagine synthase
CSW12_RS05055	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSW12_RS05250	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS05265	COG0367	asparagine synthase
CSW12_RS05280	COG0753	catalase activity
CSW12_RS05285	COG0004	ammonium transporteR
CSW12_RS05315	COG2996	Protein conserved in bacteria
CSW12_RS05350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS05365	COG0561	phosphatase activity
CSW12_RS05390	COG2267	carboxylic ester hydrolase activity
CSW12_RS05405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW12_RS05410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CSW12_RS05415	COG5504	Zn-dependent protease
CSW12_RS05425	COG0180	Tryptophanyl-tRNA synthetase
CSW12_RS05440	COG4166	transmembrane transport
CSW12_RS05445	COG0601	transmembrane transport
CSW12_RS05450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_RS05455	COG0444	Belongs to the ABC transporter superfamily
CSW12_RS05460	COG4608	Belongs to the ABC transporter superfamily
CSW12_RS05465	COG0534	Mate efflux family protein
CSW12_RS05470	COG4166	transmembrane transport
CSW12_RS05490	COG0861	Integral membrane protein TerC family
CSW12_RS05500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_RS05510	COG1164	Oligoendopeptidase f
CSW12_RS05525	COG2346	COG2346, Truncated hemoglobins
CSW12_RS05530	COG4116	CYTH
CSW12_RS05540	COG2357	RelA SpoT domain protein
CSW12_RS05550	COG0564	pseudouridine synthase activity
CSW12_RS05565	COG0772	Belongs to the SEDS family
CSW12_RS05570	COG1216	Glycosyl transferase, family 2
CSW12_RS05590	COG0463	Glycosyl transferase, family 2
CSW12_RS05590	COG0457	Tetratricopeptide repeat
CSW12_RS05610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CSW12_RS05625	COG1091	dTDP-4-dehydrorhamnose reductase activity
CSW12_RS05670	COG2153	protein acetylation
CSW12_RS05680	COG2382	esterase
CSW12_RS05705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_RS05720	COG0512	Glutamine amidotransferase of anthranilate synthase
CSW12_RS05720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSW12_RS05755	COG1620	l-lactate permease
CSW12_RS05770	COG5634	Uncharacterized conserved protein (DUF2278)
CSW12_RS05815	COG2226	methyltransferase
CSW12_RS05835	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW12_RS05845	COG1476	TRANSCRIPTIONal
CSW12_RS05890	COG4152	abc transporter atp-binding protein
CSW12_RS05895	COG1668	transmembrane transport
CSW12_RS05925	COG1686	Belongs to the peptidase S11 family
CSW12_RS05930	COG0681	Belongs to the peptidase S26 family
CSW12_RS05965	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS05975	COG1176	ABC-type spermidine putrescine transport system, permease component I
CSW12_RS05980	COG1177	transmembrane transport
CSW12_RS05995	COG2409	Drug exporters of the RND superfamily
CSW12_RS06005	COG0564	pseudouridine synthase activity
CSW12_RS06015	COG2340	Cysteine-rich secretory protein family
CSW12_RS06020	COG0247	lactate metabolic process
CSW12_RS06025	COG0277	FAD linked oxidase domain protein
CSW12_RS06030	COG3835	regulator
CSW12_RS06040	COG0745	RESPONSE REGULATOR receiver
CSW12_RS06045	COG5002	protein histidine kinase activity
CSW12_RS06050	COG2186	Transcriptional regulator
CSW12_RS06070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CSW12_RS06080	COG2116	formate transmembrane transporter activity
CSW12_RS06085	COG0861	Integral membrane protein TerC family
CSW12_RS06090	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW12_RS06100	COG2030	dehydratase
CSW12_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS06125	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSW12_RS06135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW12_RS06155	COG1840	ABC-type Fe3 transport system, periplasmic component
CSW12_RS06160	COG3842	ATPase activity
CSW12_RS06185	COG1349	DNA-binding transcription factor activity
CSW12_RS06200	COG0235	Class ii aldolase
CSW12_RS06210	COG2861	carbohydrate metabolic process
CSW12_RS06220	COG3852	Histidine kinase
CSW12_RS06225	COG1846	Transcriptional regulator
CSW12_RS06235	COG2318	DinB family
CSW12_RS06245	COG5002	protein histidine kinase activity
CSW12_RS06255	COG0720	synthase
CSW12_RS06270	COG4873	Protein conserved in bacteria
CSW12_RS06305	COG1780	Probably involved in ribonucleotide reductase function
CSW12_RS06310	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSW12_RS06325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSW12_RS06330	COG1725	Transcriptional regulator
CSW12_RS06335	COG1131	(ABC) transporter
CSW12_RS06345	COG1131	(ABC) transporter
CSW12_RS06365	COG1522	sequence-specific DNA binding
CSW12_RS06375	COG1335	isochorismatase
CSW12_RS06385	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW12_RS06390	COG2070	2-Nitropropane dioxygenase
CSW12_RS06395	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CSW12_RS06405	COG1696	Membrane protein involved in D-alanine export
CSW12_RS06430	COG0716	FMN binding
CSW12_RS06505	COG1846	Transcriptional regulator
CSW12_RS06515	COG1301	dicarboxylic acid transport
CSW12_RS06520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSW12_RS06525	COG4709	membrane
CSW12_RS06530	COG3874	Sporulation protein YtfJ
CSW12_RS06560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_RS06565	COG0028	Belongs to the TPP enzyme family
CSW12_RS06570	COG0440	acetolactate synthase activity
CSW12_RS06645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSW12_RS06660	COG1183	phosphatidylcholine synthase activity
CSW12_RS06665	COG1368	sulfuric ester hydrolase activity
CSW12_RS06675	COG0019	diaminopimelate decarboxylase activity
CSW12_RS06695	COG0529	Catalyzes the synthesis of activated sulfate
CSW12_RS06700	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSW12_RS06720	COG1648	precorrin-2 dehydrogenase activity
CSW12_RS06735	COG0733	neurotransmitter:sodium symporter activity
CSW12_RS06755	COG1757	Na H antiporter
CSW12_RS06770	COG4758	membrane
CSW12_RS06775	COG4585	Histidine kinase
CSW12_RS06780	COG2197	response regulator
CSW12_RS06795	COG1114	Component of the transport system for branched-chain amino acids
CSW12_RS06850	COG0730	response to heat
CSW12_RS06855	COG0306	phosphate transporter
CSW12_RS06860	COG1392	Phosphate transport regulator
CSW12_RS06865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_RS06880	COG3852	Histidine kinase
CSW12_RS06885	COG1801	Protein of unknown function DUF72
CSW12_RS06895	COG0582	viral genome integration into host DNA
CSW12_RS06900	COG5002	protein histidine kinase activity
CSW12_RS06915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CSW12_RS06915	COG0392	lysyltransferase activity
CSW12_RS06930	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSW12_RS06935	COG1686	Belongs to the peptidase S11 family
CSW12_RS06940	COG2715	membrane protein required for spore maturation
CSW12_RS06945	COG0700	Nucleoside recognition
CSW12_RS06950	COG1187	pseudouridine synthase activity
CSW12_RS06960	COG1333	cytochrome c biogenesis protein
CSW12_RS06965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSW12_RS06970	COG0745	RESPONSE REGULATOR receiver
CSW12_RS06975	COG5002	protein histidine kinase activity
CSW12_RS06980	COG2096	Adenosyltransferase
CSW12_RS06995	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CSW12_RS07005	COG1141	Ferredoxin
CSW12_RS07015	COG0514	ATP-dependent DNA helicase (RecQ)
CSW12_RS07020	COG1266	CAAX protease self-immunity
CSW12_RS07030	COG1408	metallophosphoesterase
CSW12_RS07035	COG0789	Transcriptional regulator
CSW12_RS07045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSW12_RS07065	COG0492	ferredoxin-NADP+ reductase activity
CSW12_RS07070	COG0252	asparaginase activity
CSW12_RS07145	COG1609	Transcriptional regulator
CSW12_RS07150	COG2056	Na+-H+ antiporter family
CSW12_RS07155	COG0596	Alpha beta hydrolase
CSW12_RS07165	COG0737	Belongs to the 5'-nucleotidase family
CSW12_RS07165	COG1525	nuclease
CSW12_RS07165	COG4085	toxin activity
CSW12_RS07180	COG0456	acetyltransferase
CSW12_RS07180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSW12_RS07185	COG0656	L-ascorbic acid biosynthetic process
CSW12_RS07190	COG0667	Aldo Keto reductase
CSW12_RS07210	COG1300	Membrane
CSW12_RS07215	COG0735	belongs to the Fur family
CSW12_RS07225	COG4974	Belongs to the 'phage' integrase family
CSW12_RS07250	COG0598	Magnesium transport protein CorA
CSW12_RS07265	COG1846	Transcriptional regulator
CSW12_RS07280	COG1131	(ABC) transporter
CSW12_RS07285	COG1725	Transcriptional regulator
CSW12_RS07295	COG1686	Belongs to the peptidase S11 family
CSW12_RS07315	COG0733	neurotransmitter:sodium symporter activity
CSW12_RS07340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW12_RS07355	COG0697	spore germination
CSW12_RS07360	COG0561	phosphatase activity
CSW12_RS07365	COG4086	secreted protein
CSW12_RS07370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSW12_RS07375	COG0456	acetyltransferase
CSW12_RS07380	COG1547	Domain of unknown function (DUF309)
CSW12_RS07410	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CSW12_RS07420	COG2188	Transcriptional regulator
CSW12_RS07430	COG3711	transcriptional antiterminator
CSW12_RS07435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CSW12_RS07435	COG1263	PTS System
CSW12_RS07435	COG2190	(PTS) system
CSW12_RS07460	COG0778	Nitroreductase
CSW12_RS07465	COG2199	diguanylate cyclase activity
CSW12_RS07475	COG2084	Dehydrogenase
CSW12_RS07510	COG0436	Aminotransferase
CSW12_RS07515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSW12_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS07540	COG1695	Transcriptional regulator
CSW12_RS07575	COG0183	Belongs to the thiolase family
CSW12_RS07590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW12_RS07650	COG3842	ATPase activity
CSW12_RS07655	COG0366	Alpha amylase catalytic
CSW12_RS07665	COG2182	Extracellular solute-binding protein
CSW12_RS07670	COG1175	transmembrane transport
CSW12_RS07675	COG3833	ABC-type maltose transport systems, permease component
CSW12_RS07680	COG1609	Transcriptional regulator
CSW12_RS07685	COG0436	Aminotransferase
CSW12_RS07695	COG2205	protein histidine kinase activity
CSW12_RS07710	COG3209	COG3209 Rhs family protein
CSW12_RS07730	COG2814	Major facilitator Superfamily
CSW12_RS07775	COG1408	metallophosphoesterase
CSW12_RS07780	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS07785	COG2200	EAL domain
CSW12_RS07800	COG4703	Protein of unknown function (DUF1797)
CSW12_RS07810	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CSW12_RS07820	COG0517	IMP dehydrogenase activity
CSW12_RS07825	COG0583	DNA-binding transcription factor activity
CSW12_RS07845	COG0569	domain protein
CSW12_RS07850	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CSW12_RS07865	COG0561	phosphatase activity
CSW12_RS07880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSW12_RS07885	COG0022	dehydrogenase e1 component
CSW12_RS07935	COG1982	Orn Lys Arg decarboxylase major
CSW12_RS07955	COG0483	inositol monophosphate 1-phosphatase activity
CSW12_RS07965	COG1217	gtp-binding protein TYPA
CSW12_RS07980	COG4896	Protein conserved in bacteria
CSW12_RS07990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CSW12_RS07995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CSW12_RS08005	COG0772	Belongs to the SEDS family
CSW12_RS08015	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CSW12_RS08050	COG3336	cytochrome c oxidase
CSW12_RS08065	COG2340	Cysteine-rich secretory protein family
CSW12_RS08080	COG0406	alpha-ribazole phosphatase activity
CSW12_RS08085	COG3679	Belongs to the UPF0342 family
CSW12_RS08100	COG0742	ribosomal rna small subunit methyltransferase
CSW12_RS08110	COG3314	Sporulation integral membrane protein YlbJ
CSW12_RS08115	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSW12_RS08120	COG3480	Lon protease (S16) C-terminal proteolytic domain
CSW12_RS08130	COG1399	metal-binding, possibly nucleic acid-binding protein
CSW12_RS08135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CSW12_RS08155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSW12_RS08175	COG0768	penicillin binding
CSW12_RS08180	COG0768	penicillin binding
CSW12_RS08200	COG0772	Belongs to the SEDS family
CSW12_RS08220	COG0849	cell division
CSW12_RS08225	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSW12_RS08235	COG1191	sigma factor activity
CSW12_RS08240	COG1191	sigma factor activity
CSW12_RS08245	COG1873	PFAM PRC-barrel domain
CSW12_RS08255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CSW12_RS08265	COG0762	integral membrane protein
CSW12_RS08270	COG2302	S4 RNA-binding domain
CSW12_RS08275	COG3599	regulation of cell shape
CSW12_RS08295	COG0564	pseudouridine synthase activity
CSW12_RS08355	COG3069	C4-dicarboxylate transmembrane transporter activity
CSW12_RS08375	COG0006	proline dipeptidase activity
CSW12_RS08400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CSW12_RS08405	COG1561	YicC-like family, N-terminal region
CSW12_RS08425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSW12_RS08430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSW12_RS08445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CSW12_RS08445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CSW12_RS08455	COG0631	protein serine/threonine phosphatase activity
CSW12_RS08460	COG2815	serine threonine protein kinase
CSW12_RS08460	COG0515	serine threonine protein kinase
CSW12_RS08470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSW12_RS08475	COG1564	THIamine pyrophosphokinase
CSW12_RS08490	COG1302	Protein conserved in bacteria
CSW12_RS08495	COG1461	Dihydroxyacetone kinase
CSW12_RS08500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSW12_RS08515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSW12_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS08525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSW12_RS08535	COG1196	nuclear chromosome segregation
CSW12_RS08540	COG0552	protein localization to endoplasmic reticulum
CSW12_RS08550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSW12_RS08560	COG1837	Belongs to the UPF0109 family
CSW12_RS08600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CSW12_RS08605	COG0758	DNA mediated transformation
CSW12_RS08610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW12_RS08620	COG4974	Belongs to the 'phage' integrase family
CSW12_RS08665	COG4589	Belongs to the CDS family
CSW12_RS08675	COG0750	zinc metalloprotease
CSW12_RS08700	COG0195	Participates in both transcription termination and antitermination
CSW12_RS08705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CSW12_RS08710	COG1358	cellular component organization or biogenesis
CSW12_RS08720	COG1550	Protein conserved in bacteria
CSW12_RS08725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CSW12_RS08735	COG0196	riboflavin kinase activity
CSW12_RS08750	COG0726	polysaccharide deacetylase
CSW12_RS08755	COG0612	Peptidase, M16
CSW12_RS08760	COG1873	PFAM PRC-barrel domain
CSW12_RS08765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW12_RS08770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSW12_RS08775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSW12_RS08780	COG0527	aspartate kinase activity
CSW12_RS08790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CSW12_RS08795	COG0740	serine-type endopeptidase activity
CSW12_RS08815	COG2188	Transcriptional regulator
CSW12_RS08820	COG1744	ABC transporter substrate-binding protein PnrA-like
CSW12_RS08825	COG3845	ABC transporter
CSW12_RS08830	COG4603	Belongs to the binding-protein-dependent transport system permease family
CSW12_RS08835	COG1079	Belongs to the binding-protein-dependent transport system permease family
CSW12_RS08840	COG0612	Peptidase, M16
CSW12_RS08845	COG0612	Peptidase, M16
CSW12_RS08850	COG0300	oxidoreductase activity
CSW12_RS08865	COG1426	Protein conserved in bacteria
CSW12_RS08870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSW12_RS08895	COG1692	metallophosphoesterase
CSW12_RS08900	COG2359	stage V sporulation protein S
CSW12_RS08910	COG0674	pyruvate-flavodoxin oxidoreductase activity
CSW12_RS08910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CSW12_RS08915	COG1013	pyruvate-flavodoxin oxidoreductase activity
CSW12_RS08925	COG4550	Control of competence regulator ComK, YlbF/YmcA
CSW12_RS08950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSW12_RS08955	COG1368	sulfuric ester hydrolase activity
CSW12_RS08970	COG3773	Cell wall hydrolase
CSW12_RS08975	COG1404	Belongs to the peptidase S8 family
CSW12_RS08985	COG2723	6-phospho-beta-galactosidase activity
CSW12_RS08990	COG2188	Transcriptional regulator
CSW12_RS09000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS09010	COG1346	cytolysis
CSW12_RS09030	COG1086	Polysaccharide biosynthesis protein
CSW12_RS09050	COG3300	MHYT domain
CSW12_RS09050	COG5001	Diguanylate cyclase
CSW12_RS09055	COG2267	carboxylic ester hydrolase activity
CSW12_RS09070	COG2364	Membrane
CSW12_RS09080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CSW12_RS09085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSW12_RS09090	COG2169	Transcriptional regulator
CSW12_RS09095	COG0708	Exodeoxyribonuclease III
CSW12_RS09100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS09105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS09110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS09115	COG1120	ATPase activity
CSW12_RS09120	COG2819	hydrolase of the alpha beta superfamily
CSW12_RS09130	COG1937	Protein conserved in bacteria
CSW12_RS09135	COG2608	mercury ion transmembrane transporter activity
CSW12_RS09140	COG2217	Heavy metal translocating P-type atpase
CSW12_RS09155	COG2116	formate transmembrane transporter activity
CSW12_RS09160	COG1408	metallophosphoesterase
CSW12_RS09175	COG1113	amino acid transport
CSW12_RS09190	COG2322	membrane
CSW12_RS09195	COG1979	alcohol dehydrogenase
CSW12_RS09200	COG1349	DNA-binding transcription factor activity
CSW12_RS09205	COG1105	Belongs to the carbohydrate kinase PfkB family
CSW12_RS09210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW12_RS09210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW12_RS09210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSW12_RS09220	COG1388	LysM domain
CSW12_RS09220	COG3584	3D domain protein
CSW12_RS09250	COG0464	growth
CSW12_RS09255	COG2860	membrane
CSW12_RS09260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSW12_RS09265	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CSW12_RS09270	COG0789	Transcriptional regulator
CSW12_RS09275	COG0174	glutamine synthetase
CSW12_RS09280	COG1695	Transcriptional regulator
CSW12_RS09300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CSW12_RS09310	COG0737	Belongs to the 5'-nucleotidase family
CSW12_RS09315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_RS09350	COG1132	(ABC) transporter
CSW12_RS09355	COG1132	(ABC) transporter
CSW12_RS09380	COG0730	response to heat
CSW12_RS09395	COG1346	cytolysis
CSW12_RS09405	COG0583	DNA-binding transcription factor activity
CSW12_RS09420	COG1131	(ABC) transporter
CSW12_RS09430	COG1473	amidohydrolase
CSW12_RS09445	COG0785	Cytochrome C biogenesis protein
CSW12_RS09450	COG4846	Membrane protein involved in cytochrome C biogenesis
CSW12_RS09480	COG2226	methyltransferase
CSW12_RS09505	COG0010	Belongs to the arginase family
CSW12_RS09510	COG1329	Transcriptional regulator
CSW12_RS09515	COG1902	pentaerythritol trinitrate reductase activity
CSW12_RS09520	COG0069	glutamate synthase activity
CSW12_RS09530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_RS09535	COG0346	lactoylglutathione lyase activity
CSW12_RS09540	COG0400	carboxylic ester hydrolase activity
CSW12_RS09545	COG5002	protein histidine kinase activity
CSW12_RS09560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS09600	COG1396	sequence-specific DNA binding
CSW12_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_RS09610	COG1268	BioY protein
CSW12_RS09615	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_RS09620	COG0183	Belongs to the thiolase family
CSW12_RS09635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CSW12_RS09645	COG2211	Major facilitator Superfamily
CSW12_RS09675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CSW12_RS09680	COG2274	protein secretion by the type I secretion system
CSW12_RS09690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_RS09715	COG0824	Thioesterase
CSW12_RS09720	COG4841	protein insertion into membrane
CSW12_RS09740	COG0745	RESPONSE REGULATOR receiver
CSW12_RS09745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW12_RS09750	COG1832	CoA-binding protein
CSW12_RS09760	COG0187	DNA topoisomerase II activity
CSW12_RS09765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSW12_RS09770	COG0673	inositol 2-dehydrogenase activity
CSW12_RS09790	COG1131	(ABC) transporter
CSW12_RS09800	COG1595	DNA-templated transcription, initiation
CSW12_RS09810	COG1316	TRANSCRIPTIONal
CSW12_RS09815	COG4166	transmembrane transport
CSW12_RS09820	COG4166	transmembrane transport
CSW12_RS09825	COG4166	transmembrane transport
CSW12_RS09830	COG2226	methyltransferase
CSW12_RS09865	COG0531	amino acid
CSW12_RS09880	COG0697	spore germination
CSW12_RS09890	COG3383	formate dehydrogenase (NAD+) activity
CSW12_RS09895	COG2427	Protein of unknown function (DUF1641)
CSW12_RS09900	COG5609	conserved protein (DUF2294)
CSW12_RS09905	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSW12_RS09920	COG2116	formate transmembrane transporter activity
CSW12_RS09925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_RS09930	COG0303	'Molybdopterin
CSW12_RS09935	COG0314	molybdopterin synthase activity
CSW12_RS09945	COG0489	protein tyrosine kinase activity
CSW12_RS09960	COG3326	Membrane
CSW12_RS09965	COG2962	Rard protein
CSW12_RS09970	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CSW12_RS09975	COG1657	PFAM Prenyltransferase squalene oxidase
CSW12_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS09990	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS10000	COG4145	pantothenate transmembrane transporter activity
CSW12_RS10015	COG0165	Argininosuccinate lyase
CSW12_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS10055	COG0716	FMN binding
CSW12_RS10090	COG2720	vancomycin resistance protein
CSW12_RS10095	COG2514	catechol 2,3-dioxygenase activity
CSW12_RS10110	COG1285	pathogenesis
CSW12_RS10120	COG3852	Histidine kinase
CSW12_RS10160	COG1876	peptidase activity
CSW12_RS10175	COG1309	transcriptional regulator
CSW12_RS10210	COG1404	Belongs to the peptidase S8 family
CSW12_RS10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSW12_RS10270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSW12_RS10290	COG0697	spore germination
CSW12_RS10310	COG3397	chitin binding
CSW12_RS10315	COG0823	Involved in the tonB-independent uptake of proteins
CSW12_RS10335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS10335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS10350	COG1183	phosphatidylcholine synthase activity
CSW12_RS10375	COG0277	FAD linked oxidase domain protein
CSW12_RS10380	COG0385	Bile acid
CSW12_RS10390	COG0457	Tetratricopeptide repeat
CSW12_RS10405	COG0604	alcohol dehydrogenase
CSW12_RS10410	COG0640	Transcriptional regulator
CSW12_RS10420	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_RS10445	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_RS10480	COG1164	Oligoendopeptidase f
CSW12_RS10485	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CSW12_RS10500	COG1193	negative regulation of DNA recombination
CSW12_RS10520	COG0583	DNA-binding transcription factor activity
CSW12_RS10535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS10560	COG3739	integral membrane protein
CSW12_RS10565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS10570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS10575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS10590	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW12_RS10595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CSW12_RS10635	COG2814	Major facilitator Superfamily
CSW12_RS10640	COG1113	amino acid transport
CSW12_RS10650	COG0604	alcohol dehydrogenase
CSW12_RS10685	COG2072	flavoprotein involved in K transport
CSW12_RS10730	COG1151	hydroxylamine reductase activity
CSW12_RS10780	COG1280	lysine exporter protein (LysE YggA)
CSW12_RS10790	COG1191	sigma factor activity
CSW12_RS10800	COG0726	polysaccharide deacetylase
CSW12_RS10810	COG1733	regulation of RNA biosynthetic process
CSW12_RS10815	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW12_RS10820	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_RS10835	COG0367	asparagine synthase
CSW12_RS10890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS10915	COG0673	inositol 2-dehydrogenase activity
CSW12_RS10920	COG2188	Transcriptional regulator
CSW12_RS10950	COG0814	amino acid
CSW12_RS10965	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_RS10970	COG2824	Alkylphosphonate utilization operon protein PhnA
CSW12_RS11005	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSW12_RS11010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CSW12_RS11015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSW12_RS11020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CSW12_RS11050	COG2706	6-phosphogluconolactonase activity
CSW12_RS11055	COG3813	Protein conserved in bacteria
CSW12_RS11060	COG1357	PFAM Pentapeptide repeats (8 copies)
CSW12_RS11065	COG0697	spore germination
CSW12_RS11090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSW12_RS11100	COG0789	Transcriptional regulator
CSW12_RS11105	COG1253	flavin adenine dinucleotide binding
CSW12_RS11135	COG0477	Major facilitator Superfamily
CSW12_RS11145	COG0500	methyltransferase
CSW12_RS11175	COG0628	permease
CSW12_RS11190	COG0110	maltose O-acetyltransferase activity
CSW12_RS11195	COG0738	Major facilitator superfamily
CSW12_RS11200	COG1940	carbohydrate kinase activity
CSW12_RS11205	COG0346	lactoylglutathione lyase activity
CSW12_RS11235	COG2365	Tyrosine phosphatase family
CSW12_RS11240	COG1011	Hydrolase
CSW12_RS11265	COG1131	(ABC) transporter
CSW12_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS11300	COG0469	pyruvate kinase activity
CSW12_RS11310	COG0778	Nitroreductase
CSW12_RS11315	COG1733	regulation of RNA biosynthetic process
CSW12_RS11335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSW12_RS11345	COG3620	sequence-specific DNA binding
CSW12_RS11355	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSW12_RS11370	COG2356	endonuclease I
CSW12_RS11375	COG1288	antiporter activity
CSW12_RS11430	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW12_RS11440	COG2031	fatty acid transporter
CSW12_RS11455	COG1131	(ABC) transporter
CSW12_RS11460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CSW12_RS11470	COG2814	Major facilitator Superfamily
CSW12_RS11475	COG1846	Transcriptional regulator
CSW12_RS11490	COG0477	Major facilitator Superfamily
CSW12_RS11500	COG2843	Capsule synthesis protein
CSW12_RS11505	COG1876	peptidase activity
CSW12_RS11525	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_RS11525	COG5632	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS11560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS11560	COG2207	Transcriptional regulator
CSW12_RS11570	COG0662	Cupin 2, conserved barrel domain protein
CSW12_RS11590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSW12_RS11610	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW12_RS11620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS11630	COG3850	Histidine kinase
CSW12_RS11630	COG5002	protein histidine kinase activity
CSW12_RS11650	COG0577	efflux transmembrane transporter activity
CSW12_RS11670	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSW12_RS11680	COG1690	Belongs to the RtcB family
CSW12_RS11690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CSW12_RS11715	COG2814	Major facilitator Superfamily
CSW12_RS11770	COG1595	DNA-templated transcription, initiation
CSW12_RS11780	COG0768	penicillin binding
CSW12_RS11800	COG2040	homocysteine
CSW12_RS11805	COG0833	amino acid
CSW12_RS11820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_RS11820	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSW12_RS11870	COG3850	Histidine kinase
CSW12_RS11870	COG5002	protein histidine kinase activity
CSW12_RS11875	COG0745	RESPONSE REGULATOR receiver
CSW12_RS11935	COG0346	lactoylglutathione lyase activity
CSW12_RS11950	COG1522	sequence-specific DNA binding
CSW12_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS11960	COG1309	transcriptional regulator
CSW12_RS11965	COG3320	Male sterility
CSW12_RS11965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSW12_RS11970	COG0640	Transcriptional regulator
CSW12_RS11975	COG0346	lactoylglutathione lyase activity
CSW12_RS11980	COG0798	PFAM Bile acid sodium symporter
CSW12_RS11990	COG1575	Belongs to the MenA family. Type 1 subfamily
CSW12_RS11995	COG0456	acetyltransferase
CSW12_RS12020	COG2814	Major facilitator Superfamily
CSW12_RS12025	COG5609	conserved protein (DUF2294)
CSW12_RS12030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSW12_RS12040	COG0288	reversible hydration of carbon dioxide
CSW12_RS12045	COG0657	acetylesterase activity
CSW12_RS12055	COG2814	Major facilitator Superfamily
CSW12_RS12065	COG0415	Belongs to the DNA photolyase family
CSW12_RS12085	COG1073	alpha beta
CSW12_RS12105	COG0598	Magnesium transport protein CorA
CSW12_RS12110	COG1846	Transcriptional regulator
CSW12_RS12145	COG1335	isochorismatase
CSW12_RS12150	COG2267	carboxylic ester hydrolase activity
CSW12_RS12160	COG0737	Belongs to the 5'-nucleotidase family
CSW12_RS12175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSW12_RS12185	COG1063	alcohol dehydrogenase
CSW12_RS12205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS12210	COG0574	Belongs to the PEP-utilizing enzyme family
CSW12_RS12210	COG3848	Pyruvate phosphate dikinase
CSW12_RS12230	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CSW12_RS12250	COG3314	Sporulation integral membrane protein YlbJ
CSW12_RS12265	COG1960	acyl-CoA dehydrogenase activity
CSW12_RS12275	COG0640	Transcriptional regulator
CSW12_RS12290	COG1414	Transcriptional regulator
CSW12_RS12295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CSW12_RS12300	COG1984	allophanate hydrolase subunit 2
CSW12_RS12330	COG0768	penicillin binding
CSW12_RS12370	COG0577	efflux transmembrane transporter activity
CSW12_RS12370	COG1136	(ABC) transporter
CSW12_RS12380	COG0745	RESPONSE REGULATOR receiver
CSW12_RS12395	COG4335	DNA alkylation repair
CSW12_RS12405	COG0833	amino acid
CSW12_RS12420	COG0730	response to heat
CSW12_RS12440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSW12_RS12440	COG0456	acetyltransferase
CSW12_RS12460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS12465	COG0697	spore germination
CSW12_RS12480	COG0456	acetyltransferase
CSW12_RS12485	COG4977	sequence-specific DNA binding
CSW12_RS12510	COG3831	ATPase activity
CSW12_RS12510	COG4884	unkown
CSW12_RS12535	COG1846	Transcriptional regulator
CSW12_RS12540	COG0778	Nitroreductase
CSW12_RS12550	COG0714	Associated with various cellular activities
CSW12_RS12590	COG0753	catalase activity
CSW12_RS12615	COG0714	Associated with various cellular activities
CSW12_RS12640	COG0346	lactoylglutathione lyase activity
CSW12_RS12645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS12670	COG3655	Transcriptional regulator
CSW12_RS12680	COG1785	Belongs to the alkaline phosphatase family
CSW12_RS12685	COG2720	vancomycin resistance protein
CSW12_RS12695	COG3239	Fatty acid desaturase
CSW12_RS12715	COG0833	amino acid
CSW12_RS12725	COG1414	Transcriptional regulator
CSW12_RS12730	COG4187	Peptidase family M20/M25/M40
CSW12_RS12735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_RS12755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS12770	COG2329	Antibiotic biosynthesis monooxygenase
CSW12_RS12795	COG1070	Carbohydrate kinase
CSW12_RS12800	COG2390	Transcriptional regulator
CSW12_RS12810	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW12_RS12815	COG1172	Belongs to the binding-protein-dependent transport system permease family
CSW12_RS12820	COG1879	ABC-type sugar transport system periplasmic component
CSW12_RS12845	COG0277	FAD linked oxidase domain protein
CSW12_RS12860	COG3584	3D domain protein
CSW12_RS12860	COG1388	LysM domain
CSW12_RS12900	COG1605	Chorismate mutase
CSW12_RS12900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSW12_RS12920	COG0287	Prephenate dehydrogenase
CSW12_RS12935	COG1309	transcriptional regulator
CSW12_RS12940	COG1033	growth of symbiont in host cell
CSW12_RS12940	COG2409	Drug exporters of the RND superfamily
CSW12_RS12945	COG0488	(ABC) transporter
CSW12_RS12950	COG1368	sulfuric ester hydrolase activity
CSW12_RS12955	COG0861	Integral membrane protein TerC family
CSW12_RS12975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS12980	COG0346	lactoylglutathione lyase activity
CSW12_RS12985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_RS12990	COG4912	Dna alkylation repair
CSW12_RS13010	COG2318	DinB family
CSW12_RS13040	COG2746	aminoglycoside 3-N-acetyltransferase activity
CSW12_RS13070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_RS13075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_RS13095	COG0628	permease
CSW12_RS13155	COG1131	(ABC) transporter
CSW12_RS13170	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CSW12_RS13180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CSW12_RS13185	COG0436	Aminotransferase
CSW12_RS13225	COG2226	methyltransferase
CSW12_RS13240	COG2261	transglycosylase associated protein
CSW12_RS13265	COG0477	Major facilitator Superfamily
CSW12_RS13265	COG2814	Major facilitator Superfamily
CSW12_RS13270	COG4533	DNA binding
CSW12_RS13275	COG0789	Transcriptional regulator
CSW12_RS13280	COG1664	Polymer-forming cytoskeletal
CSW12_RS13290	COG2814	Major facilitator Superfamily
CSW12_RS13330	COG1307	EDD domain protein, DegV family
CSW12_RS13335	COG1164	Oligoendopeptidase f
CSW12_RS13370	COG0745	RESPONSE REGULATOR receiver
CSW12_RS13375	COG3850	Histidine kinase
CSW12_RS13375	COG5002	protein histidine kinase activity
CSW12_RS13420	COG0667	Aldo Keto reductase
CSW12_RS13435	COG4948	Mandelate Racemase Muconate Lactonizing
CSW12_RS13445	COG4166	transmembrane transport
CSW12_RS13450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CSW12_RS13460	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS13505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_RS13510	COG3938	Belongs to the proline racemase family
CSW12_RS13520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSW12_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS13530	COG1115	amino acid carrier protein
CSW12_RS13535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSW12_RS13550	COG3397	chitin binding
CSW12_RS13575	COG4637	Psort location Cytoplasmic, score
CSW12_RS13610	COG0514	ATP-dependent DNA helicase (RecQ)
CSW12_RS13615	COG2105	PFAM AIG2 family protein
CSW12_RS13625	COG3973	AAA domain
CSW12_RS13670	COG2315	Protein conserved in bacteria
CSW12_RS13680	COG2205	protein histidine kinase activity
CSW12_RS13700	COG3397	chitin binding
CSW12_RS13705	COG2153	protein acetylation
CSW12_RS13735	COG0517	IMP dehydrogenase activity
CSW12_RS13735	COG4175	Glycine betaine
CSW12_RS13740	COG4176	ABC-type proline glycine betaine transport system permease component
CSW12_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS13795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSW12_RS13800	COG0022	dehydrogenase e1 component
CSW12_RS13805	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW12_RS13810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW12_RS13825	COG1959	2 iron, 2 sulfur cluster binding
CSW12_RS13840	COG1349	DNA-binding transcription factor activity
CSW12_RS13860	COG3284	Transcriptional regulator
CSW12_RS13945	COG2959	enzyme of heme biosynthesis
CSW12_RS13960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS13990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSW12_RS14000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS14005	COG0697	spore germination
CSW12_RS14010	COG0201	protein transport
CSW12_RS14025	COG0737	Belongs to the 5'-nucleotidase family
CSW12_RS14030	COG3227	Zinc metalloprotease (Elastase)
CSW12_RS14035	COG1523	belongs to the glycosyl hydrolase 13 family
CSW12_RS14050	COG0076	glutamate decarboxylase activity
CSW12_RS14055	COG0657	acetylesterase activity
CSW12_RS14060	COG1073	alpha beta
CSW12_RS14065	COG0577	efflux transmembrane transporter activity
CSW12_RS14070	COG1136	(ABC) transporter
CSW12_RS14085	COG5002	protein histidine kinase activity
CSW12_RS14090	COG0745	RESPONSE REGULATOR receiver
CSW12_RS14095	COG1011	Hydrolase
CSW12_RS14125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSW12_RS14170	COG0322	excinuclease ABC activity
CSW12_RS14210	COG4667	esterase of the alpha-beta hydrolase superfamily
CSW12_RS14235	COG3878	Protein conserved in bacteria
CSW12_RS14260	COG0592	DNA-directed DNA polymerase activity
CSW12_RS14275	COG2223	nitrite transmembrane transporter activity
CSW12_RS14285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_RS14320	COG0697	spore germination
CSW12_RS14325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS14345	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_RS14370	COG0789	Transcriptional regulator
CSW12_RS14370	COG4978	Transcriptional regulator
CSW12_RS14375	COG2814	Major facilitator Superfamily
CSW12_RS14425	COG0768	penicillin binding
CSW12_RS14430	COG0671	phosphoesterase, PA-phosphatase related
CSW12_RS14435	COG0604	alcohol dehydrogenase
CSW12_RS14440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSW12_RS14510	COG0582	viral genome integration into host DNA
CSW12_RS14515	COG2205	protein histidine kinase activity
CSW12_RS14540	COG1794	racemase activity, acting on amino acids and derivatives
CSW12_RS14545	COG1819	glycosyl
CSW12_RS14560	COG0768	penicillin binding
CSW12_RS14565	COG5002	protein histidine kinase activity
CSW12_RS14570	COG0561	phosphatase activity
CSW12_RS14610	COG2124	cytochrome p450
CSW12_RS14675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSW12_RS14685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS14690	COG0460	homoserine dehydrogenase
CSW12_RS14710	COG0577	efflux transmembrane transporter activity
CSW12_RS14715	COG1136	(ABC) transporter
CSW12_RS14730	COG0488	(ABC) transporter
CSW12_RS14745	COG2205	protein histidine kinase activity
CSW12_RS14750	COG0745	RESPONSE REGULATOR receiver
CSW12_RS14760	COG3773	Cell wall hydrolase
CSW12_RS14765	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CSW12_RS14775	COG3386	PFAM SMP-30 Gluconolaconase
CSW12_RS14785	COG0693	protein deglycase activity
CSW12_RS14790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CSW12_RS14795	COG2323	membrane
CSW12_RS14805	COG1063	alcohol dehydrogenase
CSW12_RS14820	COG2368	4-hydroxyphenylacetate
CSW12_RS14830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS14865	COG2226	methyltransferase
CSW12_RS14870	COG1733	regulation of RNA biosynthetic process
CSW12_RS14875	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS14915	COG2207	Transcriptional regulator
CSW12_RS14920	COG3227	Zinc metalloprotease (Elastase)
CSW12_RS14935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSW12_RS14960	COG1686	Belongs to the peptidase S11 family
CSW12_RS14985	COG0572	uridine kinase
CSW12_RS15005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW12_RS15010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSW12_RS15015	COG1024	Enoyl-CoA hydratase
CSW12_RS15020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSW12_RS15025	COG0511	ligase activity, forming carbon-carbon bonds
CSW12_RS15030	COG0439	Biotin carboxylase
CSW12_RS15035	COG1960	acyl-CoA dehydrogenase activity
CSW12_RS15050	COG1309	transcriptional regulator
CSW12_RS15060	COG1131	(ABC) transporter
CSW12_RS15070	COG1408	metallophosphoesterase
CSW12_RS15075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS15080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS15090	COG0768	penicillin binding
CSW12_RS15095	COG0768	penicillin binding
CSW12_RS15105	COG1595	DNA-templated transcription, initiation
CSW12_RS15110	COG0768	penicillin binding
CSW12_RS15120	COG2239	Acts as a magnesium transporter
CSW12_RS15145	COG1533	DNA photolyase activity
CSW12_RS15165	COG0814	amino acid
CSW12_RS15170	COG1760	l-serine dehydratase
CSW12_RS15175	COG1760	l-serine dehydratase
CSW12_RS15250	COG1404	Belongs to the peptidase S8 family
CSW12_RS15260	COG4585	Histidine kinase
CSW12_RS15285	COG0640	Transcriptional regulator
CSW12_RS15300	COG1846	Transcriptional regulator
CSW12_RS15320	COG1309	transcriptional regulator
CSW12_RS15345	COG1396	sequence-specific DNA binding
CSW12_RS15365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS15370	COG0741	lytic transglycosylase activity
CSW12_RS15400	COG5002	protein histidine kinase activity
CSW12_RS15425	COG2207	Transcriptional regulator
CSW12_RS15450	COG0322	excinuclease ABC activity
CSW12_RS15455	COG0531	amino acid
CSW12_RS15460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_RS15470	COG0531	amino acid
CSW12_RS15475	COG0697	spore germination
CSW12_RS15485	COG0784	Response regulator, receiver
CSW12_RS15490	COG4191	Histidine kinase
CSW12_RS15500	COG1115	amino acid carrier protein
CSW12_RS15515	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CSW12_RS15540	COG2814	Major facilitator Superfamily
CSW12_RS15555	COG1686	Belongs to the peptidase S11 family
CSW12_RS15560	COG0110	maltose O-acetyltransferase activity
CSW12_RS15565	COG0730	response to heat
CSW12_RS15575	COG2002	toxin-antitoxin pair type II binding
CSW12_RS15605	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW12_RS15665	COG1846	Transcriptional regulator
CSW12_RS15670	COG3961	Belongs to the TPP enzyme family
CSW12_RS15675	COG2226	methyltransferase
CSW12_RS15685	COG0500	methyltransferase
CSW12_RS15685	COG3615	Tellurite resistance protein tehB
CSW12_RS15700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS15715	COG1846	Transcriptional regulator
CSW12_RS15735	COG2971	BadF BadG BcrA BcrD
CSW12_RS15760	COG1649	PFAM Uncharacterised BCR, COG1649
CSW12_RS15790	COG1595	DNA-templated transcription, initiation
CSW12_RS15795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW12_RS15830	COG1396	sequence-specific DNA binding
CSW12_RS15865	COG1132	(ABC) transporter
CSW12_RS15870	COG1132	(ABC) transporter
CSW12_RS15885	COG2258	MOSC domain
CSW12_RS15890	COG0583	DNA-binding transcription factor activity
CSW12_RS15910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CSW12_RS15915	COG0583	DNA-binding transcription factor activity
CSW12_RS15945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS15955	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CSW12_RS15980	COG1247	-acetyltransferase
CSW12_RS16015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS16070	COG0028	Belongs to the TPP enzyme family
CSW12_RS16085	COG2814	Major facilitator Superfamily
CSW12_RS16095	COG1136	(ABC) transporter
CSW12_RS16100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSW12_RS16105	COG1187	pseudouridine synthase activity
CSW12_RS16125	COG1115	amino acid carrier protein
CSW12_RS16135	COG2318	DinB family
CSW12_RS16145	COG0776	regulation of translation
CSW12_RS16160	COG2814	Major facilitator Superfamily
CSW12_RS16165	COG3251	PFAM MbtH domain protein
CSW12_RS16170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSW12_RS16175	COG1535	isochorismatase
CSW12_RS16175	COG3433	isochorismatase activity
CSW12_RS16180	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSW12_RS16185	COG1169	isochorismate synthase
CSW12_RS16190	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS16200	COG2223	nitrite transmembrane transporter activity
CSW12_RS16235	COG0419	ATPase involved in DNA repair
CSW12_RS16240	COG0420	3'-5' exonuclease activity
CSW12_RS16255	COG1024	Enoyl-CoA hydratase
CSW12_RS16260	COG1280	lysine exporter protein (LysE YggA)
CSW12_RS16270	COG2084	Dehydrogenase
CSW12_RS16275	COG1960	acyl-CoA dehydrogenase activity
CSW12_RS16280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CSW12_RS16285	COG2079	MmgE PrpD family protein
CSW12_RS16290	COG0372	Belongs to the citrate synthase family
CSW12_RS16295	COG4841	protein insertion into membrane
CSW12_RS16300	COG2814	Major facilitator Superfamily
CSW12_RS16310	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSW12_RS16310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_RS16330	COG0300	oxidoreductase activity
CSW12_RS16420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_RS16425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSW12_RS16430	COG0671	phosphoesterase, PA-phosphatase related
CSW12_RS16440	COG0515	serine threonine protein kinase
CSW12_RS16440	COG4991	sh3 domain protein
CSW12_RS16440	COG3064	Membrane
CSW12_RS16475	COG1509	lysine 2,3-aminomutase activity
CSW12_RS16485	COG3829	transcription factor binding
CSW12_RS16490	COG0456	acetyltransferase
CSW12_RS16495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW12_RS16500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSW12_RS16505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSW12_RS16510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW12_RS16525	COG5506	Protein of unknown function (DUF1694)
CSW12_RS16530	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS16535	COG1253	flavin adenine dinucleotide binding
CSW12_RS16570	COG1174	glycine betaine transport
CSW12_RS16575	COG1125	glycine betaine transport
CSW12_RS16575	COG0517	IMP dehydrogenase activity
CSW12_RS16610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CSW12_RS16635	COG1064	alcohol dehydrogenase
CSW12_RS16640	COG0384	phenazine biosynthesis protein PhzF
CSW12_RS16645	COG1737	Transcriptional regulator
CSW12_RS16650	COG2197	response regulator
CSW12_RS16655	COG2203	Gaf domain
CSW12_RS16655	COG4585	Histidine kinase
CSW12_RS16660	COG0668	transmembrane transport
CSW12_RS16730	COG1396	sequence-specific DNA binding
CSW12_RS16765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_RS16770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS16775	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS16790	COG0367	asparagine synthase
CSW12_RS16795	COG0071	Belongs to the small heat shock protein (HSP20) family
CSW12_RS16800	COG1999	signal sequence binding
CSW12_RS16810	COG1307	EDD domain protein, DegV family
CSW12_RS16825	COG0805	protein transport
CSW12_RS16835	COG1272	protein, Hemolysin III
CSW12_RS16840	COG0204	Acyl-transferase
CSW12_RS16850	COG0768	penicillin binding
CSW12_RS16865	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSW12_RS16880	COG0546	phosphoglycolate phosphatase activity
CSW12_RS16890	COG4473	ABC transporter
CSW12_RS16895	COG1131	(ABC) transporter
CSW12_RS16905	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CSW12_RS16910	COG3655	Transcriptional regulator
CSW12_RS16920	COG0456	acetyltransferase
CSW12_RS16930	COG1794	racemase activity, acting on amino acids and derivatives
CSW12_RS16940	COG2610	gluconate transmembrane transporter activity
CSW12_RS16965	COG0733	neurotransmitter:sodium symporter activity
CSW12_RS17015	COG1674	ftsk spoiiie
CSW12_RS17035	COG0017	Asparaginyl-tRNA synthetase
CSW12_RS17045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSW12_RS17085	COG0018	arginyl-trna synthetase
CSW12_RS17090	COG2136	Putative SAM-dependent methyltransferase
CSW12_RS17090	COG2521	methyltransferase
CSW12_RS17110	COG1413	lyase activity
CSW12_RS17125	COG0629	single-stranded DNA binding
CSW12_RS17140	COG0488	(ABC) transporter
CSW12_RS17145	COG1418	mRNA catabolic process
CSW12_RS17160	COG2359	stage V sporulation protein S
CSW12_RS17195	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CSW12_RS17200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSW12_RS17205	COG2146	nitrite reductase [NAD(P)H] activity
CSW12_RS17210	COG1587	Uroporphyrinogen-III synthase
CSW12_RS17210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSW12_RS17220	COG1648	precorrin-2 dehydrogenase activity
CSW12_RS17240	COG2223	nitrite transmembrane transporter activity
CSW12_RS17250	COG0314	molybdopterin synthase activity
CSW12_RS17255	COG0303	'Molybdopterin
CSW12_RS17260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_RS17265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSW12_RS17270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW12_RS17275	COG2181	nitrate reductase activity
CSW12_RS17280	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CSW12_RS17285	COG1140	nitrate reductase beta subunit
CSW12_RS17290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CSW12_RS17295	COG0714	Associated with various cellular activities
CSW12_RS17300	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CSW12_RS17305	COG1305	Transglutaminase-like
CSW12_RS17310	COG0386	Belongs to the glutathione peroxidase family
CSW12_RS17320	COG0426	domain, Protein
CSW12_RS17320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSW12_RS17335	COG1595	DNA-templated transcription, initiation
CSW12_RS17340	COG0604	alcohol dehydrogenase
CSW12_RS17350	COG0346	lactoylglutathione lyase activity
CSW12_RS17375	COG2226	methyltransferase
CSW12_RS17400	COG3874	Sporulation protein YtfJ
CSW12_RS17435	COG0456	acetyltransferase
CSW12_RS17465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS17470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS17475	COG1819	glycosyl
CSW12_RS17490	COG4106	trans-aconitate 2-methyltransferase activity
CSW12_RS17495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSW12_RS17505	COG2814	Major facilitator Superfamily
CSW12_RS17510	COG1846	Transcriptional regulator
CSW12_RS17525	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS17540	COG2211	Major facilitator Superfamily
CSW12_RS17555	COG1876	peptidase activity
CSW12_RS17570	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS17590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW12_RS17595	COG1114	Component of the transport system for branched-chain amino acids
CSW12_RS17620	COG1253	flavin adenine dinucleotide binding
CSW12_RS17625	COG2839	Protein conserved in bacteria
CSW12_RS17630	COG0702	epimerase
CSW12_RS17645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_RS17655	COG1607	acyl-coa hydrolase
CSW12_RS17660	COG3689	TIGRFAM TIGR03943 family protein
CSW12_RS17665	COG0701	Predicted permease
CSW12_RS17675	COG2244	polysaccharide biosynthetic process
CSW12_RS17680	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS17685	COG1051	belongs to the nudix hydrolase family
CSW12_RS17690	COG5337	Spore coat protein CotH
CSW12_RS17715	COG4166	transmembrane transport
CSW12_RS17725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSW12_RS17735	COG0702	epimerase
CSW12_RS17740	COG0803	Belongs to the bacterial solute-binding protein 9 family
CSW12_RS17745	COG0456	acetyltransferase
CSW12_RS17750	COG0523	cobalamin synthesis protein
CSW12_RS17755	COG4989	oxidoreductase activity
CSW12_RS17760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS17765	COG1231	oxidoreductase activity
CSW12_RS17790	COG0783	Belongs to the Dps family
CSW12_RS17795	COG3949	Membrane
CSW12_RS17815	COG0840	transmembrane signaling receptor activity
CSW12_RS17840	COG2814	Major facilitator Superfamily
CSW12_RS17845	COG0667	Aldo Keto reductase
CSW12_RS17850	COG0640	Transcriptional regulator
CSW12_RS17855	COG1404	Belongs to the peptidase S8 family
CSW12_RS17860	COG2002	toxin-antitoxin pair type II binding
CSW12_RS17865	COG0577	efflux transmembrane transporter activity
CSW12_RS17900	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSW12_RS17910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS17915	COG1279	arginine transmembrane transporter activity
CSW12_RS17920	COG2814	Major facilitator Superfamily
CSW12_RS17930	COG1082	Xylose isomerase domain protein TIM barrel
CSW12_RS17940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSW12_RS17960	COG1247	-acetyltransferase
CSW12_RS17965	COG1285	pathogenesis
CSW12_RS17980	COG5002	protein histidine kinase activity
CSW12_RS17985	COG0745	RESPONSE REGULATOR receiver
CSW12_RS17995	COG1316	TRANSCRIPTIONal
CSW12_RS18020	COG0460	homoserine dehydrogenase
CSW12_RS18050	COG4122	O-methyltransferase activity
CSW12_RS18055	COG0300	oxidoreductase activity
CSW12_RS18060	COG5002	protein histidine kinase activity
CSW12_RS18065	COG0745	RESPONSE REGULATOR receiver
CSW12_RS18080	COG0791	NLP P60 protein
CSW12_RS18080	COG1388	LysM domain
CSW12_RS18095	COG1686	Belongs to the peptidase S11 family
CSW12_RS18130	COG1216	Glycosyl transferase, family 2
CSW12_RS18140	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CSW12_RS18145	COG4988	ABC transporter
CSW12_RS18150	COG1294	oxidase, subunit
CSW12_RS18155	COG1271	oxidase subunit
CSW12_RS18175	COG1942	4-Oxalocrotonate Tautomerase
CSW12_RS18185	COG0583	DNA-binding transcription factor activity
CSW12_RS18205	COG0411	ABC transporter
CSW12_RS18215	COG0523	cobalamin synthesis protein
CSW12_RS18225	COG1231	oxidoreductase activity
CSW12_RS18235	COG0628	permease
CSW12_RS18250	COG0778	Nitroreductase
CSW12_RS18255	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSW12_RS18260	COG1959	2 iron, 2 sulfur cluster binding
CSW12_RS18265	COG0583	DNA-binding transcription factor activity
CSW12_RS18270	COG0697	spore germination
CSW12_RS18275	COG4549	nuclear export factor GLE1
CSW12_RS18280	COG1276	copper resistance
CSW12_RS18280	COG2372	response to copper ion
CSW12_RS18295	COG1114	Component of the transport system for branched-chain amino acids
CSW12_RS18315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW12_RS18330	COG2132	Multicopper oxidase
CSW12_RS18340	COG0006	proline dipeptidase activity
CSW12_RS18350	COG4846	Membrane protein involved in cytochrome C biogenesis
CSW12_RS18360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CSW12_RS18365	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS18375	COG2390	Transcriptional regulator
CSW12_RS18380	COG1309	transcriptional regulator
CSW12_RS18400	COG0456	acetyltransferase
CSW12_RS18415	COG2309	aminopeptidase activity
CSW12_RS18450	COG0531	amino acid
CSW12_RS18455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CSW12_RS18470	COG1914	H( )-stimulated, divalent metal cation uptake system
CSW12_RS18475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS18520	COG4166	transmembrane transport
CSW12_RS18525	COG1309	transcriptional regulator
CSW12_RS18530	COG2814	Major facilitator Superfamily
CSW12_RS18550	COG0427	acetyl-CoA hydrolase
CSW12_RS18555	COG3279	Response regulator of the LytR AlgR family
CSW12_RS18565	COG3384	dioxygenase
CSW12_RS18570	COG2814	Major facilitator Superfamily
CSW12_RS18590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSW12_RS18610	COG0028	Belongs to the TPP enzyme family
CSW12_RS18615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_RS18625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW12_RS18655	COG2323	membrane
CSW12_RS18660	COG5566	PFAM Mor transcription activator
CSW12_RS18675	COG0733	neurotransmitter:sodium symporter activity
CSW12_RS18695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_RS18700	COG2223	nitrite transmembrane transporter activity
CSW12_RS18705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSW12_RS18715	COG0477	Major facilitator Superfamily
CSW12_RS18725	COG1695	Transcriptional regulator
CSW12_RS18795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW12_RS18800	COG0784	Response regulator, receiver
CSW12_RS18805	COG4191	Histidine kinase
CSW12_RS18810	COG0281	malic enzyme
CSW12_RS18815	COG1027	Aspartate ammonia-lyase
CSW12_RS18825	COG0528	UMP kinase activity
CSW12_RS18830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_RS18845	COG1131	(ABC) transporter
CSW12_RS18885	COG2733	membrane
CSW12_RS18905	COG0457	Tetratricopeptide repeat
CSW12_RS18920	COG0785	Cytochrome C biogenesis protein
CSW12_RS18940	COG3340	Belongs to the peptidase S51 family
CSW12_RS18945	COG0534	Mate efflux family protein
CSW12_RS18975	COG0789	Transcriptional regulator
CSW12_RS18980	COG1757	Na H antiporter
CSW12_RS18995	COG0701	Predicted permease
CSW12_RS19005	COG0523	cobalamin synthesis protein
CSW12_RS19015	COG0697	spore germination
CSW12_RS19020	COG1802	Transcriptional regulator
CSW12_RS19050	COG0367	asparagine synthase
CSW12_RS19135	COG3842	ATPase activity
CSW12_RS19140	COG0583	DNA-binding transcription factor activity
CSW12_RS19165	COG2329	Antibiotic biosynthesis monooxygenase
CSW12_RS19205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSW12_RS19210	COG4786	Flagellar basal body rod
CSW12_RS19215	COG1419	protein localization to endoplasmic reticulum
CSW12_RS19220	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSW12_RS19225	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CSW12_RS19235	COG1987	bacterial-type flagellum assembly
CSW12_RS19240	COG1338	Plays a role in the flagellum-specific transport system
CSW12_RS19250	COG1776	CheC inhibitor of MCP methylation
CSW12_RS19250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_RS19255	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_RS19265	COG0741	lytic transglycosylase activity
CSW12_RS19270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_RS19275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_RS19280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_RS19285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_RS19295	COG0784	Response regulator, receiver
CSW12_RS19295	COG0835	chemotaxis
CSW12_RS19330	COG1157	protein secretion by the type III secretion system
CSW12_RS19340	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_RS19345	COG1766	The M ring may be actively involved in energy transduction
CSW12_RS19355	COG1558	bacterial-type flagellum-dependent cell motility
CSW12_RS19360	COG1815	bacterial-type flagellum-dependent cell motility
CSW12_RS19375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CSW12_RS19380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CSW12_RS19405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CSW12_RS19420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CSW12_RS19420	COG1776	CheC inhibitor of MCP methylation
CSW12_RS19425	COG0643	Histidine kinase
CSW12_RS19425	COG2198	Histidine kinase
CSW12_RS19430	COG2201	protein-glutamate methylesterase activity
CSW12_RS19435	COG1360	Flagellar Motor Protein
CSW12_RS19440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSW12_RS19450	COG1923	regulation of RNA biosynthetic process
CSW12_RS19500	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CSW12_RS19505	COG2323	membrane
CSW12_RS19515	COG4978	Transcriptional regulator
CSW12_RS19515	COG0789	Transcriptional regulator
CSW12_RS19520	COG0475	glutathione-regulated potassium exporter activity
CSW12_RS19530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW12_RS19535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSW12_RS19555	COG1280	lysine exporter protein (LysE YggA)
CSW12_RS19560	COG3403	YqcI/YcgG family
CSW12_RS19595	COG0328	RNA-DNA hybrid ribonuclease activity
CSW12_RS19615	COG0454	-acetyltransferase
CSW12_RS19630	COG0438	transferase activity, transferring glycosyl groups
CSW12_RS19635	COG1215	transferase activity, transferring glycosyl groups
CSW12_RS19650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSW12_RS19675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW12_RS19725	COG0456	acetyltransferase
CSW12_RS19735	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSW12_RS19745	COG2311	Membrane
CSW12_RS19750	COG2233	PERMEase
CSW12_RS19760	COG0024	Methionine aminopeptidase
CSW12_RS19770	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CSW12_RS19775	COG1199	ATP-dependent helicase activity
CSW12_RS19785	COG0116	Belongs to the methyltransferase superfamily
CSW12_RS19845	COG4499	WXG100 protein secretion system (Wss), protein YukC
CSW12_RS19845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_RS19855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSW12_RS19860	COG3935	DnaD domain protein
CSW12_RS19880	COG1199	ATP-dependent helicase activity
CSW12_RS19880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSW12_RS19920	COG0438	transferase activity, transferring glycosyl groups
CSW12_RS19940	COG1694	Mazg nucleotide pyrophosphohydrolase
CSW12_RS19950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS19960	COG2738	Putative neutral zinc metallopeptidase
CSW12_RS19975	COG4347	Protein of unknown function (DUF1405)
CSW12_RS19980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CSW12_RS19980	COG2010	Cytochrome c
CSW12_RS19985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CSW12_RS20005	COG0457	Tetratricopeptide repeat
CSW12_RS20030	COG0142	geranyltranstransferase activity
CSW12_RS20040	COG0142	geranyltranstransferase activity
CSW12_RS20055	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CSW12_RS20075	COG0456	acetyltransferase
CSW12_RS20080	COG1073	alpha beta
CSW12_RS20095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSW12_RS20095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSW12_RS20100	COG0307	riboflavin synthase, alpha
CSW12_RS20130	COG2226	methyltransferase
CSW12_RS20130	COG1073	alpha beta
CSW12_RS20145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CSW12_RS20160	COG1757	Na H antiporter
CSW12_RS20165	COG0737	Belongs to the 5'-nucleotidase family
CSW12_RS20175	COG1522	sequence-specific DNA binding
CSW12_RS20220	COG0300	oxidoreductase activity
CSW12_RS20225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS20230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_RS20235	COG1760	l-serine dehydratase
CSW12_RS20240	COG1760	l-serine dehydratase
CSW12_RS20275	COG1285	pathogenesis
CSW12_RS20295	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSW12_RS20300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS20315	COG1376	ErfK ybiS ycfS ynhG family protein
CSW12_RS20320	COG4129	membrane
CSW12_RS20325	COG1126	abc transporter atp-binding protein
CSW12_RS20330	COG0765	amino acid transport
CSW12_RS20335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSW12_RS20355	COG2323	membrane
CSW12_RS20360	COG0772	Belongs to the SEDS family
CSW12_RS20370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSW12_RS20375	COG0022	dehydrogenase e1 component
CSW12_RS20380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSW12_RS20385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSW12_RS20400	COG0280	phosphate acetyltransferase
CSW12_RS20410	COG3829	transcription factor binding
CSW12_RS20410	COG3290	protein histidine kinase activity
CSW12_RS20420	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_RS20425	COG3093	addiction module antidote protein HigA
CSW12_RS20450	COG0750	zinc metalloprotease
CSW12_RS20455	COG0497	DNA recombination
CSW12_RS20465	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CSW12_RS20475	COG0142	geranyltranstransferase activity
CSW12_RS20500	COG1302	Protein conserved in bacteria
CSW12_RS20505	COG0439	Biotin carboxylase
CSW12_RS20510	COG0511	ligase activity, forming carbon-carbon bonds
CSW12_RS20555	COG3854	ATPases associated with a variety of cellular activities
CSW12_RS20580	COG0006	proline dipeptidase activity
CSW12_RS20595	COG3872	metal-dependent enzyme
CSW12_RS20605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSW12_RS20640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS20650	COG1609	Transcriptional regulator
CSW12_RS20660	COG2076	Multidrug Resistance protein
CSW12_RS20665	COG2076	Multidrug Resistance protein
CSW12_RS20700	COG1131	(ABC) transporter
CSW12_RS20705	COG1725	Transcriptional regulator
CSW12_RS20740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW12_RS20815	COG1459	type II secretion system
CSW12_RS20820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSW12_RS20880	COG1410	methionine synthase
CSW12_RS20880	COG0646	methionine synthase
CSW12_RS20885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSW12_RS20885	COG0646	methionine synthase
CSW12_RS20890	COG0626	cystathionine gamma-synthase activity
CSW12_RS20895	COG0626	cystathionine gamma-synthase activity
CSW12_RS20915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS20925	COG1940	carbohydrate kinase activity
CSW12_RS20930	COG4483	Protein conserved in bacteria
CSW12_RS20935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSW12_RS20940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CSW12_RS20945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSW12_RS20950	COG0704	Plays a role in the regulation of phosphate uptake
CSW12_RS20960	COG0573	inorganic phosphate transmembrane transporter activity
CSW12_RS20965	COG0573	inorganic phosphate transmembrane transporter activity
CSW12_RS20970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSW12_RS20975	COG0768	penicillin binding
CSW12_RS20980	COG0477	Major facilitator Superfamily
CSW12_RS20985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSW12_RS20995	COG5521	maltodextrose utilization protein MalA
CSW12_RS21010	COG0735	belongs to the Fur family
CSW12_RS21015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSW12_RS21020	COG1121	(ABC) transporter
CSW12_RS21025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS21055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSW12_RS21060	COG2384	SAM-dependent methyltransferase
CSW12_RS21070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CSW12_RS21075	COG0358	DNA primase activity
CSW12_RS21095	COG0517	IMP dehydrogenase activity
CSW12_RS21110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSW12_RS21115	COG0295	cytidine deaminase activity
CSW12_RS21120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CSW12_RS21130	COG1480	7TM receptor with intracellular HD hydrolase
CSW12_RS21135	COG1702	phosphate starvation-inducible protein PhoH
CSW12_RS21155	COG1610	YqeY-like protein
CSW12_RS21160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CSW12_RS21170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CSW12_RS21175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSW12_RS21205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSW12_RS21210	COG1733	regulation of RNA biosynthetic process
CSW12_RS21235	COG1466	dna polymerase III delta subunit
CSW12_RS21245	COG2333	competence protein COMEC
CSW12_RS21245	COG0658	competence protein
CSW12_RS21250	COG2131	deaminase
CSW12_RS21270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CSW12_RS21275	COG2226	methyltransferase
CSW12_RS21280	COG0799	negative regulation of ribosome biogenesis
CSW12_RS21285	COG1713	HD superfamily hydrolase involved in NAD metabolism
CSW12_RS21295	COG1534	Rna-binding protein
CSW12_RS21305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CSW12_RS21310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CSW12_RS21345	COG0778	Nitroreductase
CSW12_RS21350	COG2357	RelA SpoT domain protein
CSW12_RS21360	COG1785	Belongs to the alkaline phosphatase family
CSW12_RS21375	COG2267	carboxylic ester hydrolase activity
CSW12_RS21410	COG1404	Belongs to the peptidase S8 family
CSW12_RS21415	COG3186	Phenylalanine-4-hydroxylase
CSW12_RS21425	COG2514	catechol 2,3-dioxygenase activity
CSW12_RS21430	COG2259	Doxx family
CSW12_RS21475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS21490	COG1012	belongs to the aldehyde dehydrogenase family
CSW12_RS21490	COG1454	alcohol dehydrogenase
CSW12_RS21495	COG0626	cystathionine gamma-synthase activity
CSW12_RS21500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_RS21525	COG0768	penicillin binding
CSW12_RS21540	COG0826	peptidase U32
CSW12_RS21545	COG0826	peptidase U32
CSW12_RS21550	COG4122	O-methyltransferase activity
CSW12_RS21555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSW12_RS21570	COG4472	Bacterial protein of unknown function (DUF965)
CSW12_RS21585	COG0628	permease
CSW12_RS21605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSW12_RS21620	COG1104	cysteine desulfurase activity
CSW12_RS21625	COG1959	2 iron, 2 sulfur cluster binding
CSW12_RS21630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSW12_RS21650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSW12_RS21675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSW12_RS21685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSW12_RS21685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CSW12_RS21690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CSW12_RS21695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW12_RS21695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSW12_RS21705	COG2244	polysaccharide biosynthetic process
CSW12_RS21710	COG2323	membrane
CSW12_RS21720	COG1862	Preprotein translocase
CSW12_RS21750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CSW12_RS21780	COG0157	Belongs to the NadC ModD family
CSW12_RS21785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CSW12_RS21790	COG1104	cysteine desulfurase activity
CSW12_RS21795	COG1827	regulation of RNA biosynthetic process
CSW12_RS21800	COG2258	MOSC domain
CSW12_RS21805	COG0077	Prephenate dehydratase
CSW12_RS21810	COG0577	efflux transmembrane transporter activity
CSW12_RS21815	COG0577	efflux transmembrane transporter activity
CSW12_RS21820	COG1136	(ABC) transporter
CSW12_RS21825	COG5002	protein histidine kinase activity
CSW12_RS21830	COG0745	RESPONSE REGULATOR receiver
CSW12_RS21840	COG3290	protein histidine kinase activity
CSW12_RS21850	COG2868	ribosomal protein
CSW12_RS21860	COG1530	ribonuclease E activity
CSW12_RS21865	COG1994	Peptidase M50
CSW12_RS21870	COG0739	heme binding
CSW12_RS21875	COG2894	cell division
CSW12_RS21895	COG1077	Cell shape determining protein MreB Mrl
CSW12_RS21920	COG0285	dihydrofolate synthase activity
CSW12_RS21935	COG1388	LysM domain
CSW12_RS21945	COG0113	porphobilinogen synthase activity
CSW12_RS21950	COG1587	Uroporphyrinogen-III synthase
CSW12_RS21960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CSW12_RS21970	COG1846	Transcriptional regulator
CSW12_RS21980	COG1764	response to oxidative stress
CSW12_RS21995	COG1067	ATP-dependent peptidase activity
CSW12_RS21995	COG0470	DNA polymerase III
CSW12_RS22050	COG0622	Phosphoesterase
CSW12_RS22065	COG5401	PFAM Sporulation and spore germination
CSW12_RS22085	COG1309	transcriptional regulator
CSW12_RS22095	COG2197	response regulator
CSW12_RS22105	COG0402	S-adenosylhomocysteine deaminase activity
CSW12_RS22110	COG1983	PspC domain protein
CSW12_RS22115	COG1396	sequence-specific DNA binding
CSW12_RS22120	COG0697	spore germination
CSW12_RS22130	COG1959	2 iron, 2 sulfur cluster binding
CSW12_RS22135	COG1668	transmembrane transport
CSW12_RS22140	COG4152	abc transporter atp-binding protein
CSW12_RS22145	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSW12_RS22150	COG1360	Flagellar Motor Protein
CSW12_RS22155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CSW12_RS22165	COG1876	peptidase activity
CSW12_RS22170	COG0824	Thioesterase
CSW12_RS22175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSW12_RS22180	COG1053	succinate dehydrogenase
CSW12_RS22185	COG2009	succinate dehydrogenase
CSW12_RS22190	COG1719	4-vinyl reductase, 4VR
CSW12_RS22200	COG3118	belongs to the thioredoxin family
CSW12_RS22205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CSW12_RS22210	COG2086	electron transfer activity
CSW12_RS22215	COG1024	Enoyl-CoA hydratase
CSW12_RS22220	COG1309	transcriptional regulator
CSW12_RS22225	COG0318	PFAM AMP-dependent synthetase and ligase
CSW12_RS22255	COG2318	DinB family
CSW12_RS22285	COG1131	(ABC) transporter
CSW12_RS22290	COG2205	protein histidine kinase activity
CSW12_RS22295	COG0745	RESPONSE REGULATOR receiver
CSW12_RS22305	COG4895	conserved protein (DUF2196)
CSW12_RS22310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CSW12_RS22320	COG4509	Sortase family
CSW12_RS22325	COG1120	ATPase activity
CSW12_RS22340	COG5386	Cell surface protein
CSW12_RS22350	COG5386	Cell surface protein
CSW12_RS22355	COG1114	Component of the transport system for branched-chain amino acids
CSW12_RS22360	COG1187	pseudouridine synthase activity
CSW12_RS22375	COG1796	DNA polymerase
CSW12_RS22375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CSW12_RS22380	COG1286	toxin biosynthetic process
CSW12_RS22420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CSW12_RS22425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSW12_RS22435	COG1418	mRNA catabolic process
CSW12_RS22455	COG2814	Major facilitator Superfamily
CSW12_RS22460	COG1566	PFAM secretion protein HlyD family protein
CSW12_RS22465	COG1309	transcriptional regulator
CSW12_RS22470	COG1363	Peptidase, m42
CSW12_RS22495	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CSW12_RS22510	COG1484	DNA-dependent DNA replication
CSW12_RS22515	COG3611	Membrane attachment protein
CSW12_RS22525	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CSW12_RS22535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW12_RS22540	COG0237	dephospho-CoA kinase activity
CSW12_RS22545	COG1971	Probably functions as a manganese efflux pump
CSW12_RS22555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW12_RS22555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CSW12_RS22560	COG5002	protein histidine kinase activity
CSW12_RS22565	COG0745	RESPONSE REGULATOR receiver
CSW12_RS22590	COG0538	isocitrate dehydrogenase activity
CSW12_RS22595	COG0372	Belongs to the citrate synthase family
CSW12_RS22610	COG0628	permease
CSW12_RS22615	COG3030	protein affecting phage T7 exclusion by the F plasmid
CSW12_RS22640	COG1725	Transcriptional regulator
CSW12_RS22645	COG0281	malic enzyme
CSW12_RS22650	COG0587	DNA-directed DNA polymerase activity
CSW12_RS22665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CSW12_RS22680	COG4109	DRTGG domain
CSW12_RS22695	COG0006	proline dipeptidase activity
CSW12_RS22725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS22730	COG0662	Cupin 2, conserved barrel domain protein
CSW12_RS22745	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS22750	COG0589	response to stress
CSW12_RS22795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS22820	COG0827	DNA restriction-modification system
CSW12_RS22825	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CSW12_RS22830	COG3874	Sporulation protein YtfJ
CSW12_RS22850	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CSW12_RS22870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW12_RS22885	COG1104	cysteine desulfurase activity
CSW12_RS22895	COG0583	DNA-binding transcription factor activity
CSW12_RS22900	COG0697	spore germination
CSW12_RS22905	COG1309	transcriptional regulator
CSW12_RS22910	COG1956	GAF domain-containing protein
CSW12_RS22915	COG0626	cystathionine gamma-synthase activity
CSW12_RS22955	COG1595	DNA-templated transcription, initiation
CSW12_RS22965	COG0110	maltose O-acetyltransferase activity
CSW12_RS22970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSW12_RS22975	COG0454	-acetyltransferase
CSW12_RS22980	COG0517	IMP dehydrogenase activity
CSW12_RS22985	COG0123	including yeast histone deacetylase and acetoin utilization protein
CSW12_RS23000	COG0745	RESPONSE REGULATOR receiver
CSW12_RS23005	COG5002	protein histidine kinase activity
CSW12_RS23010	COG0666	response to abiotic stimulus
CSW12_RS23040	COG1609	Transcriptional regulator
CSW12_RS23055	COG1605	Chorismate mutase
CSW12_RS23055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSW12_RS23060	COG1605	Chorismate mutase
CSW12_RS23060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CSW12_RS23065	COG4851	CamS sex pheromone cAM373 precursor
CSW12_RS23070	COG3118	belongs to the thioredoxin family
CSW12_RS23080	COG2309	aminopeptidase activity
CSW12_RS23100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS23105	COG0697	spore germination
CSW12_RS23110	COG0789	Transcriptional regulator
CSW12_RS23125	COG1674	ftsk spoiiie
CSW12_RS23130	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS23140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSW12_RS23150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_RS23155	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CSW12_RS23160	COG1363	Peptidase, m42
CSW12_RS23170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS23190	COG0510	thiamine kinase activity
CSW12_RS23195	COG1523	belongs to the glycosyl hydrolase 13 family
CSW12_RS23205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CSW12_RS23210	COG1349	DNA-binding transcription factor activity
CSW12_RS23215	COG1187	pseudouridine synthase activity
CSW12_RS23220	COG2244	polysaccharide biosynthetic process
CSW12_RS23225	COG2081	HI0933 family
CSW12_RS23230	COG2814	Major facilitator Superfamily
CSW12_RS23240	COG3832	glyoxalase III activity
CSW12_RS23265	COG1329	Transcriptional regulator
CSW12_RS23290	COG0314	molybdopterin synthase activity
CSW12_RS23295	COG1763	Mo-molybdopterin cofactor biosynthetic process
CSW12_RS23300	COG0303	'Molybdopterin
CSW12_RS23310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CSW12_RS23315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSW12_RS23340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS23350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSW12_RS23390	COG2814	Major facilitator Superfamily
CSW12_RS23395	COG0475	glutathione-regulated potassium exporter activity
CSW12_RS23400	COG0490	domain, Protein
CSW12_RS23405	COG0582	viral genome integration into host DNA
CSW12_RS23420	COG1136	(ABC) transporter
CSW12_RS23440	COG1242	4 iron, 4 sulfur cluster binding
CSW12_RS23445	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CSW12_RS23455	COG1794	racemase activity, acting on amino acids and derivatives
CSW12_RS23480	COG2267	carboxylic ester hydrolase activity
CSW12_RS23485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSW12_RS23490	COG0671	phosphoesterase, PA-phosphatase related
CSW12_RS23495	COG0438	transferase activity, transferring glycosyl groups
CSW12_RS23600	COG5002	protein histidine kinase activity
CSW12_RS23605	COG3852	Histidine kinase
CSW12_RS23610	COG2267	carboxylic ester hydrolase activity
CSW12_RS23615	COG1368	sulfuric ester hydrolase activity
CSW12_RS23630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSW12_RS23635	COG1116	anion transmembrane transporter activity
CSW12_RS23640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSW12_RS23665	COG0494	nUDIX hydrolase
CSW12_RS23695	COG1854	S-ribosylhomocysteine lyase activity
CSW12_RS23705	COG0288	reversible hydration of carbon dioxide
CSW12_RS23710	COG1271	oxidase subunit
CSW12_RS23715	COG1294	oxidase, subunit
CSW12_RS23735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS23760	COG1842	Phage shock protein A
CSW12_RS23785	COG3859	Proton-coupled thiamine transporter YuaJ
CSW12_RS23790	COG5002	protein histidine kinase activity
CSW12_RS23795	COG0745	RESPONSE REGULATOR receiver
CSW12_RS23820	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CSW12_RS23825	COG1597	lipid kinase activity
CSW12_RS23855	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS23865	COG0577	efflux transmembrane transporter activity
CSW12_RS23870	COG1136	(ABC) transporter
CSW12_RS23875	COG2207	Transcriptional regulator
CSW12_RS23875	COG3708	Transcriptional regulator
CSW12_RS23885	COG5658	integral membrane protein
CSW12_RS23890	COG0640	Transcriptional regulator
CSW12_RS23895	COG0745	RESPONSE REGULATOR receiver
CSW12_RS23900	COG2205	protein histidine kinase activity
CSW12_RS23915	COG0577	efflux transmembrane transporter activity
CSW12_RS23920	COG0577	efflux transmembrane transporter activity
CSW12_RS23925	COG1136	(ABC) transporter
CSW12_RS23930	COG0577	efflux transmembrane transporter activity
CSW12_RS23945	COG2188	Transcriptional regulator
CSW12_RS23965	COG3964	amidohydrolase
CSW12_RS23995	COG4948	Mandelate Racemase Muconate Lactonizing
CSW12_RS24015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CSW12_RS24020	COG0596	Alpha beta hydrolase
CSW12_RS24030	COG1169	isochorismate synthase
CSW12_RS24035	COG1575	Belongs to the MenA family. Type 1 subfamily
CSW12_RS24040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSW12_RS24045	COG1278	Cold shock
CSW12_RS24075	COG0058	SHG alpha-glucan phosphorylase activity
CSW12_RS24085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CSW12_RS24105	COG1404	Belongs to the peptidase S8 family
CSW12_RS24120	COG1309	transcriptional regulator
CSW12_RS24260	COG1285	pathogenesis
CSW12_RS24265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSW12_RS24285	COG2155	Conserved Protein
CSW12_RS24290	COG1098	S1 RNA binding domain
CSW12_RS24295	COG0436	Aminotransferase
CSW12_RS24300	COG1522	sequence-specific DNA binding
CSW12_RS24305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CSW12_RS24310	COG2267	carboxylic ester hydrolase activity
CSW12_RS24320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CSW12_RS24335	COG5018	Exonuclease
CSW12_RS24340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW12_RS24365	COG2050	protein possibly involved in aromatic compounds catabolism
CSW12_RS24375	COG1268	BioY protein
CSW12_RS24380	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSW12_RS24385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSW12_RS24400	COG3584	3D domain protein
CSW12_RS24415	COG1252	NADH dehydrogenase
CSW12_RS24430	COG3708	Transcriptional regulator
CSW12_RS24445	COG1683	Conserved Protein
CSW12_RS24455	COG4122	O-methyltransferase activity
CSW12_RS24480	COG0316	Belongs to the HesB IscA family
CSW12_RS24495	COG1252	NADH dehydrogenase
CSW12_RS24505	COG2274	protein secretion by the type I secretion system
CSW12_RS24510	COG0390	transport system, permease component
CSW12_RS24520	COG2824	Alkylphosphonate utilization operon protein PhnA
CSW12_RS24545	COG4837	Protein of unknown function (DUF1462)
CSW12_RS24550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CSW12_RS24560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSW12_RS24565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSW12_RS24585	COG1358	cellular component organization or biogenesis
CSW12_RS24595	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSW12_RS24600	COG0647	UMP catabolic process
CSW12_RS24610	COG2445	Protein of unknown function DUF86
CSW12_RS24615	COG1494	fructose-1,6-bisphosphatase
CSW12_RS24635	COG4470	Protein conserved in bacteria
CSW12_RS24645	COG0789	Transcriptional regulator
CSW12_RS24650	COG4377	Putative membrane peptidase family (DUF2324)
CSW12_RS24675	COG0739	heme binding
CSW12_RS24685	COG3377	Domain of unknown function (DUF1805)
CSW12_RS24700	COG0719	Fe-S assembly protein
CSW12_RS24705	COG0822	iron-sulfur transferase activity
CSW12_RS24710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSW12_RS24715	COG0719	Fe-S assembly protein
CSW12_RS24720	COG0396	ATPase activity
CSW12_RS24725	COG1464	Belongs to the NlpA lipoprotein family
CSW12_RS24730	COG1464	Belongs to the NlpA lipoprotein family
CSW12_RS24735	COG2011	ABC-type metal ion transport system permease component
CSW12_RS24750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CSW12_RS24755	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CSW12_RS24770	COG1393	Belongs to the ArsC family
CSW12_RS24790	COG0039	L-malate dehydrogenase activity
CSW12_RS24810	COG1309	transcriptional regulator
CSW12_RS24815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSW12_RS24820	COG1960	acyl-CoA dehydrogenase activity
CSW12_RS24825	COG0183	Belongs to the thiolase family
CSW12_RS24830	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSW12_RS24830	COG1024	Enoyl-CoA hydratase
CSW12_RS24840	COG1686	Belongs to the peptidase S11 family
CSW12_RS24855	COG0011	TIGRFAM Protein of
CSW12_RS24860	COG0840	transmembrane signaling receptor activity
CSW12_RS24875	COG2814	Major facilitator Superfamily
CSW12_RS24880	COG0531	amino acid
CSW12_RS24905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS24945	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS24955	COG1376	ErfK ybiS ycfS ynhG family protein
CSW12_RS24960	COG0745	RESPONSE REGULATOR receiver
CSW12_RS24965	COG5002	protein histidine kinase activity
CSW12_RS24995	COG0840	transmembrane signaling receptor activity
CSW12_RS25000	COG2151	metal-sulfur cluster biosynthetic enzyme
CSW12_RS25005	COG3227	Zinc metalloprotease (Elastase)
CSW12_RS25025	COG0586	Pfam SNARE associated Golgi protein
CSW12_RS25030	COG0475	glutathione-regulated potassium exporter activity
CSW12_RS25035	COG0490	domain, Protein
CSW12_RS25045	COG1115	amino acid carrier protein
CSW12_RS25050	COG0783	Belongs to the Dps family
CSW12_RS25065	COG1611	Belongs to the LOG family
CSW12_RS25075	COG1528	Iron-storage protein
CSW12_RS25085	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS25090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS25095	COG1115	amino acid carrier protein
CSW12_RS25100	COG1115	amino acid carrier protein
CSW12_RS25105	COG2910	NAD(P)H-binding
CSW12_RS25130	COG0656	L-ascorbic acid biosynthetic process
CSW12_RS25135	COG2814	Major facilitator Superfamily
CSW12_RS25145	COG1733	regulation of RNA biosynthetic process
CSW12_RS25155	COG1252	NADH dehydrogenase
CSW12_RS25210	COG0488	(ABC) transporter
CSW12_RS25215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CSW12_RS25230	COG1335	isochorismatase
CSW12_RS25245	COG1522	sequence-specific DNA binding
CSW12_RS25250	COG0288	reversible hydration of carbon dioxide
CSW12_RS25255	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CSW12_RS25260	COG2233	PERMEase
CSW12_RS25310	COG0557	exoribonuclease II activity
CSW12_RS25315	COG1647	Serine aminopeptidase, S33
CSW12_RS25320	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSW12_RS25325	COG1346	cytolysis
CSW12_RS25360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSW12_RS25375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CSW12_RS25390	COG4152	abc transporter atp-binding protein
CSW12_RS25395	COG4585	Histidine kinase
CSW12_RS25425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CSW12_RS25440	COG2323	membrane
CSW12_RS25455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSW12_RS25465	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CSW12_RS25475	COG1051	belongs to the nudix hydrolase family
CSW12_RS25485	COG0492	ferredoxin-NADP+ reductase activity
CSW12_RS25490	COG0457	Tetratricopeptide repeat
CSW12_RS25495	COG0110	maltose O-acetyltransferase activity
CSW12_RS25515	COG1950	PFAM Membrane protein of
CSW12_RS25520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSW12_RS25540	COG0789	Transcriptional regulator
CSW12_RS25570	COG0583	DNA-binding transcription factor activity
CSW12_RS25580	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSW12_RS25585	COG0488	(ABC) transporter
CSW12_RS25595	COG1132	(ABC) transporter
CSW12_RS25600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW12_RS25605	COG0793	Belongs to the peptidase S41A family
CSW12_RS25605	COG3409	Peptidoglycan-binding domain 1 protein
CSW12_RS25610	COG2177	Part of the ABC transporter FtsEX involved in
CSW12_RS25615	COG2884	Cell division ATP-binding protein ftsE
CSW12_RS25645	COG1131	(ABC) transporter
CSW12_RS25675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CSW12_RS25680	COG1278	Cold shock
CSW12_RS25685	COG1040	competence protein
CSW12_RS25695	COG0791	NLP P60 protein
CSW12_RS25695	COG1388	LysM domain
CSW12_RS25700	COG1733	regulation of RNA biosynthetic process
CSW12_RS25710	COG1307	EDD domain protein, DegV family
CSW12_RS25715	COG1739	Uncharacterized protein family UPF0029
CSW12_RS25720	COG1316	TRANSCRIPTIONal
CSW12_RS25725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CSW12_RS25735	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSW12_RS25745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CSW12_RS25745	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CSW12_RS25765	COG1486	melibiose metabolic process
CSW12_RS25770	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW12_RS25775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW12_RS25795	COG1447	Phosphotransferase system cellobiose-specific component IIA
CSW12_RS25805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CSW12_RS25810	COG1301	dicarboxylic acid transport
CSW12_RS25825	COG1511	domain protein
CSW12_RS25830	COG0583	DNA-binding transcription factor activity
CSW12_RS25835	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CSW12_RS25840	COG1271	oxidase subunit
CSW12_RS25845	COG1294	oxidase, subunit
CSW12_RS25850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CSW12_RS25880	COG1620	l-lactate permease
CSW12_RS25895	COG2389	metal-binding protein
CSW12_RS25910	COG1368	sulfuric ester hydrolase activity
CSW12_RS25925	COG0791	NLP P60 protein
CSW12_RS25925	COG1388	LysM domain
CSW12_RS25930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CSW12_RS25940	COG1215	transferase activity, transferring glycosyl groups
CSW12_RS25950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW12_RS25960	COG3584	3D domain protein
CSW12_RS25960	COG1388	LysM domain
CSW12_RS25985	COG4715	Zinc finger, swim domain protein
CSW12_RS25990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CSW12_RS26030	COG0577	efflux transmembrane transporter activity
CSW12_RS26035	COG1136	(ABC) transporter
CSW12_RS26055	COG2271	Major facilitator Superfamily
CSW12_RS26070	COG5002	protein histidine kinase activity
CSW12_RS26075	COG0745	RESPONSE REGULATOR receiver
CSW12_RS26080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSW12_RS26100	COG1216	Glycosyl transferase, family 2
CSW12_RS26100	COG1442	glycosyl transferase family 8
CSW12_RS26110	COG0438	transferase activity, transferring glycosyl groups
CSW12_RS26115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSW12_RS26125	COG1181	Belongs to the D-alanine--D-alanine ligase family
CSW12_RS26135	COG1086	Polysaccharide biosynthesis protein
CSW12_RS26140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSW12_RS26145	COG4464	protein tyrosine phosphatase activity
CSW12_RS26150	COG0489	protein tyrosine kinase activity
CSW12_RS26155	COG3944	biosynthesis protein
CSW12_RS26160	COG0489	protein tyrosine kinase activity
CSW12_RS26175	COG1609	Transcriptional regulator
CSW12_RS26185	COG0739	heme binding
CSW12_RS26200	COG3279	Response regulator of the LytR AlgR family
CSW12_RS26205	COG2385	sporulation resulting in formation of a cellular spore
CSW12_RS26220	COG4836	Membrane
CSW12_RS26225	COG1007	ATP synthesis coupled electron transport
CSW12_RS26230	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSW12_RS26235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSW12_RS26245	COG0839	Belongs to the complex I subunit 6 family
CSW12_RS26265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSW12_RS26280	COG5001	Diguanylate cyclase
CSW12_RS26280	COG3300	MHYT domain
CSW12_RS26335	COG0356	it plays a direct role in the translocation of protons across the membrane
CSW12_RS26375	COG0698	ribose 5-phosphate isomerase
CSW12_RS26390	COG2190	(PTS) system
CSW12_RS26395	COG2259	Doxx family
CSW12_RS26400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSW12_RS26415	COG0009	L-threonylcarbamoyladenylate synthase
CSW12_RS26455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CSW12_RS26460	COG1494	fructose-1,6-bisphosphatase
CSW12_RS26480	COG4821	SIS domain
CSW12_RS26500	COG1960	acyl-CoA dehydrogenase activity
CSW12_RS26505	COG1960	acyl-CoA dehydrogenase activity
CSW12_RS26510	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSW12_RS26515	COG0183	Belongs to the thiolase family
CSW12_RS26520	COG0247	lactate metabolic process
CSW12_RS26520	COG2181	nitrate reductase activity
CSW12_RS26525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSW12_RS26535	COG3300	MHYT domain
CSW12_RS26535	COG5001	Diguanylate cyclase
CSW12_RS26550	COG3227	Zinc metalloprotease (Elastase)
CSW12_RS26555	COG2197	response regulator
CSW12_RS26560	COG4585	Histidine kinase
CSW12_RS26565	COG0842	Transport permease protein
CSW12_RS26570	COG1131	(ABC) transporter
CSW12_RS26575	COG0024	Methionine aminopeptidase
CSW12_RS26585	COG2234	aminopeptidase activity
CSW12_RS26595	COG1595	DNA-templated transcription, initiation
CSW12_RS26605	COG4506	Protein conserved in bacteria
CSW12_RS26610	COG1619	proteins homologs of microcin C7 resistance protein MccF
CSW12_RS26640	COG2814	Major facilitator Superfamily
CSW12_RS26645	COG0789	Transcriptional regulator
CSW12_RS26650	COG0584	glycerophosphoryl diester phosphodiesterase
CSW12_RS26655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSW12_RS26665	COG1994	Peptidase M50
CSW12_RS26675	COG1078	dGTPase activity
CSW12_RS26680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CSW12_RS26685	COG1120	ATPase activity
CSW12_RS26690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS26695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSW12_RS26715	COG0280	phosphate acetyltransferase
CSW12_RS26730	COG3773	Cell wall hydrolase
CSW12_RS26740	COG2363	Small membrane protein
CSW12_RS26755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSW12_RS26760	COG2233	PERMEase
CSW12_RS26765	COG0561	phosphatase activity
CSW12_RS26770	COG2814	Major facilitator Superfamily
CSW12_RS26780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CSW12_RS26785	COG1131	(ABC) transporter
CSW12_RS26790	COG2755	lipolytic protein G-D-S-L family
CSW12_RS26795	COG1609	Transcriptional regulator
CSW12_RS26805	COG0460	homoserine dehydrogenase
CSW12_RS26815	COG2873	o-acetylhomoserine
CSW12_RS26825	COG1011	Hydrolase
CSW12_RS26830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSW12_RS26840	COG2197	response regulator
CSW12_RS26845	COG4585	Histidine kinase
CSW12_RS26845	COG2203	Gaf domain
CSW12_RS26850	COG0351	phosphomethylpyrimidine kinase
CSW12_RS26855	COG3706	GGDEF domain
CSW12_RS26860	COG2879	small protein
CSW12_RS26865	COG1966	Carbon starvation protein
CSW12_RS26870	COG3279	Response regulator of the LytR AlgR family
CSW12_RS26875	COG0477	Major facilitator Superfamily
CSW12_RS26885	COG0438	transferase activity, transferring glycosyl groups
CSW12_RS26900	COG0840	transmembrane signaling receptor activity
CSW12_RS26910	COG1607	acyl-coa hydrolase
CSW12_RS26920	COG1216	Glycosyl transferase, family 2
CSW12_RS26930	COG0488	(ABC) transporter
CSW12_RS26945	COG0463	Glycosyl transferase, family 2
CSW12_RS26950	COG1309	transcriptional regulator
CSW12_RS26955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSW12_RS26960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW12_RS26960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CSW12_RS26965	COG0628	permease
CSW12_RS26985	COG3275	phosphorelay sensor kinase activity
CSW12_RS26990	COG2814	Major facilitator Superfamily
CSW12_RS26995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSW12_RS27000	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CSW12_RS27030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSW12_RS27035	COG2801	Transposase and inactivated derivatives
CSW12_RS27040	COG2801	Transposase and inactivated derivatives
CSW12_RS27060	COG1695	Transcriptional regulator
CSW12_RS27065	COG1132	(ABC) transporter
CSW12_RS27070	COG0515	serine threonine protein kinase
CSW12_RS27100	COG1272	protein, Hemolysin III
CSW12_RS27125	COG1164	Oligoendopeptidase f
CSW12_RS27135	COG5002	protein histidine kinase activity
CSW12_RS27150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSW12_RS27155	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CSW12_RS27160	COG4853	Protein conserved in bacteria
CSW12_RS27170	COG5002	protein histidine kinase activity
CSW12_RS27175	COG0745	RESPONSE REGULATOR receiver
CSW12_RS27205	COG0305	Participates in initiation and elongation during chromosome replication
CSW12_RS27215	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CSW12_RS27220	COG4241	membrane
CSW12_RS27230	COG0629	single-stranded DNA binding
CSW12_RS27240	COG0012	GTP binding
CSW12_RS27245	COG4481	Protein conserved in bacteria
CSW12_RS27250	COG0668	transmembrane transport
CSW12_RS27260	COG1475	DNA binding
CSW12_RS27265	COG1192	Involved in chromosome partitioning
CSW12_RS27290	COG1847	R3H domain protein
CSW12_RS27305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CSW12_RS27315	COG0592	DNA-directed DNA polymerase activity
CSW12_RS27320	COG2501	S4 domain
CSW12_RS27330	COG0187	DNA topoisomerase II activity
CSW12_RS27335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CSW12_RS27370	COG0516	GMP reductase activity
CSW12_RS27370	COG0517	IMP dehydrogenase activity
CSW12_RS27375	COG1686	Belongs to the peptidase S11 family
CSW12_RS27405	COG1428	Deoxynucleoside kinase
CSW12_RS27410	COG1428	Deoxynucleoside kinase
CSW12_RS27415	COG1335	isochorismatase
CSW12_RS27425	COG0590	tRNA wobble adenosine to inosine editing
CSW12_RS27435	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSW12_RS27490	COG1982	Orn Lys Arg decarboxylase major
CSW12_RS27500	COG0470	DNA polymerase III
CSW12_RS27505	COG1774	PSP1 C-terminal conserved region
CSW12_RS27515	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CSW12_RS27525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CSW12_RS27530	COG2002	toxin-antitoxin pair type II binding
CSW12_RS27540	COG0084	hydrolase, TatD family'
CSW12_RS27560	COG4466	Protein conserved in bacteria
CSW12_RS27575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CSW12_RS27580	COG0251	oxidation-reduction process
CSW12_RS27610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSW12_RS27615	COG2002	toxin-antitoxin pair type II binding
CSW12_RS27620	COG2244	polysaccharide biosynthetic process
CSW12_RS27625	COG3956	TIGRFAM MazG family protein
CSW12_RS27630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSW12_RS27650	COG1098	S1 RNA binding domain
CSW12_RS27665	COG2208	phosphoserine phosphatase activity
CSW12_RS27675	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CSW12_RS27680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSW12_RS27695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSW12_RS27700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSW12_RS27705	COG0512	Glutamine amidotransferase of anthranilate synthase
CSW12_RS27710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSW12_RS27715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSW12_RS27720	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CSW12_RS27725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSW12_RS27730	COG1396	sequence-specific DNA binding
CSW12_RS27735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSW12_RS27825	COG3880	PFAM UvrB UvrC protein
CSW12_RS27835	COG0542	response to heat
CSW12_RS27840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CSW12_RS27850	COG4956	integral membrane protein (PIN domain superfamily)
CSW12_RS27870	COG1045	serine acetyltransferase
CSW12_RS27885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSW12_RS27890	COG3688	RNA-binding protein containing a PIN domain
CSW12_RS27905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CSW12_RS27910	COG0250	Participates in transcription elongation, termination and antitermination
CSW12_RS27915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CSW12_RS27930	COG0222	ribosome binding
CSW12_RS27935	COG2813	Specifically methylates the guanine in position
CSW12_RS27945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CSW12_RS27950	COG1358	cellular component organization or biogenesis
CSW12_RS27955	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CSW12_RS27980	COG0051	transcription antitermination factor activity, RNA binding
CSW12_RS27985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CSW12_RS28025	COG0255	Belongs to the universal ribosomal protein uL29 family
CSW12_RS28085	COG0201	protein transport
CSW12_RS28095	COG0024	Methionine aminopeptidase
CSW12_RS28105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CSW12_RS28140	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CSW12_RS28165	COG0860	N-Acetylmuramoyl-L-alanine amidase
CSW12_RS28170	COG0489	protein tyrosine kinase activity
CSW12_RS28180	COG2194	sulfuric ester hydrolase activity
CSW12_RS28185	COG0726	polysaccharide deacetylase
CSW12_RS28270	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CSW12_RS28275	COG4856	YbbR-like protein
CSW12_RS28315	COG1028	Short-chain dehydrogenase reductase Sdr
CSW12_RS28320	COG2011	ABC-type metal ion transport system permease component
CSW12_RS28325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSW12_RS28330	COG1464	Belongs to the NlpA lipoprotein family
CSW12_RS28335	COG0604	alcohol dehydrogenase
CSW12_RS28345	COG0277	FAD linked oxidase domain protein
CSW12_RS28350	COG2271	Major facilitator Superfamily
CSW12_RS28360	COG2814	Major facilitator Superfamily
CSW12_RS28380	COG0601	transmembrane transport
CSW12_RS28385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_RS28390	COG0444	Belongs to the ABC transporter superfamily
CSW12_RS28395	COG4608	Belongs to the ABC transporter superfamily
CSW12_RS28400	COG4166	transmembrane transport
CSW12_RS28415	COG4166	transmembrane transport
CSW12_RS28420	COG4166	transmembrane transport
CSW12_RS28425	COG0656	L-ascorbic acid biosynthetic process
CSW12_RS28450	COG4149	molybdate abc transporter
CSW12_RS28455	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSW12_RS28460	COG1910	domain protein
CSW12_RS28475	COG0697	spore germination
CSW12_RS28490	COG0204	Acyl-transferase
CSW12_RS28505	COG1609	Transcriptional regulator
CSW12_RS28515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CSW12_RS28535	COG5298	Protein conserved in bacteria
CSW12_RS28565	COG0488	(ABC) transporter
CSW12_RS28580	COG0747	negative chemotaxis
CSW12_RS28585	COG0601	transmembrane transport
CSW12_RS28590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSW12_RS28595	COG0444	Belongs to the ABC transporter superfamily
CSW12_RS28600	COG4608	Belongs to the ABC transporter superfamily
CSW12_RS28605	COG0561	phosphatase activity
CSW12_RS28635	COG3185	4-Hydroxyphenylpyruvate dioxygenase
CSW12_RS28640	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSW12_RS28650	COG0531	amino acid
CSW12_RS28655	COG2814	Major facilitator Superfamily
CSW12_RS28665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSW12_RS28680	COG0705	Rhomboid family
CSW12_RS28690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSW12_RS28695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSW12_RS28700	COG0864	Transcriptional regulator
CSW12_RS28705	COG2337	Toxic component of a toxin-antitoxin (TA) module
CSW12_RS28710	COG2183	response to ionizing radiation
CSW12_RS28810	COG0802	atpase or kinase
CSW12_RS28815	COG1214	PFAM Peptidase M22, glycoprotease
CSW12_RS28820	COG0456	acetyltransferase
CSW12_RS28830	COG0488	(ABC) transporter
CSW12_RS28845	COG1266	CAAX protease self-immunity
CSW12_RS28865	COG2252	PERMEase
CSW12_RS28875	COG5002	protein histidine kinase activity
CSW12_RS28905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSW12_RS28925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSW12_RS28930	COG0506	proline dehydrogenase activity
CSW12_RS28980	COG1215	transferase activity, transferring glycosyl groups
CSW12_RS29000	COG0697	spore germination
CSW12_RS29055	COG1215	transferase activity, transferring glycosyl groups
CSW12_RS29145	COG2801	Transposase and inactivated derivatives
CSW12_RS29400	COG3209	COG3209 Rhs family protein
CSW12_RS29405	COG0582	viral genome integration into host DNA
CSW12_RS29420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS29455	COG1136	(ABC) transporter
CSW12_RS29525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CSW12_RS29540	COG4644	lycopene metabolic process
CSW12_RS29575	COG2801	Transposase and inactivated derivatives
CSW12_RS29675	COG2801	Transposase and inactivated derivatives
CSW12_RS29740	COG1396	sequence-specific DNA binding
CSW12_RS29770	COG0457	Tetratricopeptide repeat
CSW12_RS29875	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSW12_RS29915	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_RS29920	COG0288	reversible hydration of carbon dioxide
CSW12_RS29940	COG2755	lipolytic protein G-D-S-L family
CSW12_RS29940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CSW12_RS30035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CSW12_RS30060	COG4644	lycopene metabolic process
CSW12_RS30085	COG0270	DNA (cytosine-5-)-methyltransferase activity
CSW12_RS30115	COG2002	toxin-antitoxin pair type II binding
CSW12_RS30120	COG1923	regulation of RNA biosynthetic process
CSW12_RS30190	COG1215	transferase activity, transferring glycosyl groups
CSW12_RS30235	COG0697	spore germination
CSW12_RS30245	COG4644	lycopene metabolic process
CSW12_RS30360	COG1923	regulation of RNA biosynthetic process
CSW12_RS30365	COG2002	toxin-antitoxin pair type II binding
CSW12_RS30455	COG0741	lytic transglycosylase activity
CSW12_RS30455	COG0791	NLP P60 protein
CSW12_RS30505	COG1396	sequence-specific DNA binding
CSW12_RS30525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSW12_RS30565	COG3344	reverse transcriptase
CSW12_RS30620	COG1785	Belongs to the alkaline phosphatase family
CSW12_RS30655	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CSW12_RS30670	COG2755	lipolytic protein G-D-S-L family
CSW12_RS30670	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CSW12_RS30695	COG0288	reversible hydration of carbon dioxide
CSW12_RS30700	COG0659	secondary active sulfate transmembrane transporter activity
CSW12_RS30815	COG1073	alpha beta
CSW12_RS30825	COG0745	RESPONSE REGULATOR receiver
CSW12_RS30875	COG1396	sequence-specific DNA binding
CSW12_RS30945	COG3505	Type IV secretory pathway VirD4
CSW12_RS30980	COG3883	PFAM NLP P60 protein
CSW12_RS30980	COG0791	NLP P60 protein
CSW12_RS31050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CSW12_RS31070	COG2002	toxin-antitoxin pair type II binding
CSW12_RS31085	COG0328	RNA-DNA hybrid ribonuclease activity
CSW12_RS31085	COG3341	Caulimovirus viroplasmin
CSW12_RS31165	COG3344	reverse transcriptase
CSW12_RS31200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII